LOCUS       DAZAOD010000001       103047 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000001 DAZAOD010000000
VERSION     DAZAOD010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 103047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 103047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..103047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.001"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..3127)
                     /locus_tag="ACHDPO_000001"
     CDS             complement(<1..3127)
                     /locus_tag="ACHDPO_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367671.1"
                     /translation="MSQWNTIDELRDIFIRKYTDSELSNELEKACSEEYELMRDYNGR
                     QILELLQNVDDAYGDIKSENDASNDEVKVQITYKNNILEVGNTGTSFSKDTIERLCLG
                     RASNKSSQNIGNKGTGFRSLLNDAEWVELYSGEFAIRFSEEFTKKLFEQYVSRDSDKF
                     SELIFEQKKNWKKEDYDLCFPIMNCPQPINKIDSGFDTLIRVKLKETNLSKGTSVSKQ
                     LQQPFYKSLLFLPNITKIVIETTDDEKISEKIVDGNDVLIEKSDVTGQSPSEEYFVFD
                     KESMIGDKVAKIALAVSKDSDYDYSKEKLYCYFPVRNFGTPIHALINAPFITNNSRDD
                     VPDDSEQINKKIFIEVLKFISEVAEKLSKPEYEDIALKMVTPFKENKLWDLDVFDLMN
                     EFLGILSNAQILPTVNWQYISIKDNPKLFLQEFPEELIGETFSTLLQLLETNENDQLV
                     QELANYNEYTGLSFVVDELSDKINILSSSWENRIRTKVFLWWSEQYKSSPIVPKLLKD
                     NSDNWLMKSDKVFLPTDTGVTVLPKELSSWVSLSILKQTYVDELIYQIKTSSSWKNKW
                     EETANAYKAERTGDKRILDAFSEKYLAIEFTEQSSSDLIIGTINRQIDTVEKSISFIN
                     WFYDNYNEKLSAGSELSKVPFNLPNVAGDVQPSNKMYIGKEYGNELGDKLFQDTDYTA
                     LKKIDCSSFAEERDFLSFILRCGVSKYPKIYDNDSLKNDVGFKKFIYNKYKNEIKFTN
                     INYLTSKYISNFEELIDKLDTKDIVNWLNQDEELTDLLSSVKKESSASQQSNWSGLYF
                     NSNEYVKYILNKTAWIKIDGEKYSPRQIVLYEKLQAHVPGLYGVSEQSLMELLGQRIV
                     EQLDFRKNMAMFSDDEIRAILVELPKFDKGEISRRLYNELIRNKKGMNPTYSTEGLSV
                     LAKDGFFYPNKELRYADKRLPKSIEKQMRFIYVPEKASTTTIYEWLGVERFKTNLKLE
                     TFELLEDYSEDFKKEIDDIKTAVLSTIDDNSKNVSSLKRIQIIPCSKISAKDVEQDGQ
                     SIVLEDYYFVES"
     gene            complement(3250..4800)
                     /locus_tag="ACHDPO_000002"
     CDS             complement(3250..4800)
                     /locus_tag="ACHDPO_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3367672.1"
                     /translation="MAGKQVTVIPMKPRQWAAENTEEKPKLKVAAYCRVSTEMEEQAS
                     SYEAQVQHYTDYIQRNPDWELVGIFADEGISGTGTKKRDGFNRMIEACQNGEVEYIIT
                     KSISRFARNTVDCLQYIRQLKELKIAVFFEKENINTMDAKGEVLLTIMASLAQQESQS
                     LSQNTKMGVQYRFQQGQLRINHNHFLGYTKDEDGNLVIEPKEAEVIKRIFREYLEGSS
                     LQEIANGLMADGILTGGKRKLWRGEGVRLILRNEKYMGDALLQKTYTTDFLTKKRVKN
                     DGSYAQQYYVEDSHPAIIPKDIFMQAQQELDRRKSMKNKKSQCFSGKYALSGITVCGD
                     CGNAYRRVHWKNRGTVWRCKSRVDKREHNCTGRTIYETDLHGAVIKAINETLIDRDAF
                     LQQLNDNINSVMTDGLTDRLAELDSQLKELEAEIISLAVGGQGYDELASQIFSLRDER
                     DAVAKQIAANTNLQQRVDEMVVFVKEHDVINEYNEVLVRRLIEKVTIFEKNIVVDFKS
                     GVRVTVEI"
     gene            complement(4802..5167)
                     /locus_tag="ACHDPO_000003"
     CDS             complement(4802..5167)
                     /locus_tag="ACHDPO_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3367673.1"
                     /translation="MDEQQAQQIREFFNIYLEGVGLQEAGKRSGINKPHPFMKRILMN
                     EVYLGNEIYPKIIDEDIFFQADLEQERRIKFFKKRKEIKVPDTKVIPTHFKSGKITEK
                     YSDPFKQAQYAYSKIKEVK"
     gene            complement(5215..6768)
                     /locus_tag="ACHDPO_000004"
     CDS             complement(5215..6768)
                     /locus_tag="ACHDPO_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3367674.1"
                     /translation="MKTIHKLARPELPEASKLKVAAYARVSTSSNEQLASLQTQITHY
                     ENHIKNHEQWDYVGVYYDEGISGTKTVKRDGLKRLIKDAELGKIDLILTKSISRFSRN
                     TVDCLNLVRQLTDIGVTIFFEKENINTGDMESELLLSILSSLAESESYSHSENLKWAI
                     RNRMSKGKFKAYPPYGYKRKGYDFHIVAAEAKVVKQMFQWALDGISTGMIAKRLNDGK
                     QFTKRGANWQATSVRSILKNEVYTGTLTMQQTFVDDQYKRRINKGELPMYQIKNNHEP
                     IVSKEDYDRVQELIRRKAEAKGNTGDGKKYTKRYAFSGNIICDKCGSKFKRVHTYWKG
                     NTKKVQWKCTGHLKNKDSCDALPITDEDLKVAYLTMLNKLIFGHKLVLEPFMKSLNKA
                     GANQEGLEVLADEIDKIQEKLEVLASLTASSILSTKVSLEEQSKLQQERAVAQEKQRL
                     IIESVNGKSTQQIELEALYKFARMAEMLTDWDEDLFKKFTNSITVYNRQEVGFELKCG
                     LLLKERLPE"
     gene            complement(6829..7002)
                     /locus_tag="ACHDPO_000005"
     CDS             complement(6829..7002)
                     /locus_tag="ACHDPO_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HFN3367675.1"
                     /translation="MTNKKTEINYSDEAAYYISQQILLNLLVTGKINLEEYVKIDNKN
                     RETFNPFLSRIMV"
     gene            7297..7602
                     /locus_tag="ACHDPO_000006"
     CDS             7297..7602
                     /locus_tag="ACHDPO_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019299341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367676.1"
                     /translation="MSSFDMEGLEKEYEHFCKSATTKELEEFDESFKQEFEKCFKTIE
                     AEEALYQFLQANINAMNNRMESIESPLFCINYKEQVFQLRNHLILMQNAVNTYLKEN"
     gene            complement(7663..8700)
                     /locus_tag="ACHDPO_000007"
     CDS             complement(7663..8700)
                     /locus_tag="ACHDPO_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014572406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HFN3367677.1"
                     /translation="MVTFKDLLPEPTESQQAFILDHGKTEDDGQLKYADDAKSYGWNM
                     RQYGKLKAGAVVLNRHPGKITKDRKWEIYGGGYVESISEPDEAGNVTAVITHAFTIEP
                     AIKQGDSFIENFDWNTPSKKKRKKPNSWAYFWDQYGMNEITYADFVALIENRHLIPID
                     DTQSLPSELDLTNEEVEEIEQESSKGFTVLVDEVGPNRTNGTQKRKFTGRHTDWERVN
                     KAKQKTGALGEEIVLDFLIQEAEKNKTKLPEHVSKTEGDGHGYDICAFDQSGNEIHIE
                     VKASKTNFSDGFEMSTNEVAASLGDTPYKIYFVHDLDVASKVCKIKIYDGPITEENFT
                     MVPTSYKIFNK"
     gene            complement(8816..9724)
                     /locus_tag="ACHDPO_000008"
     CDS             complement(8816..9724)
                     /locus_tag="ACHDPO_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFN3367678.1"
                     /translation="MGISNLATKYGFQSFSHYSNGRSGAKVDKIVIHHMATTNYDIVP
                     DIWKTREASAHYGIGKNGEIRAYVDEGNTAWHAGNWNANISSIGIEHCNSTGSPNWGI
                     NQATIDASAKLCADIAKRYGLGKLVVNKNIFPHSHFSATSCPGQLLGKLQEIADKANA
                     INNGSSTPSTPASGLYRVRKSWADAKSQIGAYKDLNNAKRAADSHSGYKVFDQNGNQV
                     YPSGSSTSNVKTLVVQVSGLNVRNKPSLSGAVVGSYNKGATWTLPKSEKMTIADGWVW
                     ARCPIGYCAVGKNTGKTESDDYILIS"
     gene            complement(9714..10133)
                     /locus_tag="ACHDPO_000009"
     CDS             complement(9714..10133)
                     /locus_tag="ACHDPO_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin family protein"
                     /protein_id="HFN3367679.1"
                     /translation="MKEVWNWIQLAIAGGGGVIGWYVGGIDGLIYTLVTFVVVDYVTG
                     LLRAINEKKLSSKIGAKGITKKIMIFLLVGVAHMLDVEVIKGGNVLRDAVIFFYISNE
                     GISLLENAVAIGLPVPEKLREILQQLHEKKEETENGN"
     gene            complement(10134..10541)
                     /locus_tag="ACHDPO_000010"
     CDS             complement(10134..10541)
                     /locus_tag="ACHDPO_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HFN3367680.1"
                     /translation="MLKIRNEDLVDVMSFLKGFDLPPKISRVRTKLAKLIQVKVDELY
                     QDEVDLLQKYGKKDEHGNLVQHDGAFSLIPETATEYHKEKADLLNEETHINVDELQDK
                     LPLLVAGFENSEVTISGKDAEMLDLILEQLEDL"
     gene            complement(10528..10695)
                     /locus_tag="ACHDPO_000011"
     CDS             complement(10528..10695)
                     /locus_tag="ACHDPO_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367681.1"
                     /translation="MNEEKEEVIVTEPIEADIPKPMKVGTDMVDLLVMVVDDLCVQIG
                     DLKEKIDNAQN"
     gene            complement(10705..14595)
                     /locus_tag="ACHDPO_000012"
     CDS             complement(10705..14595)
                     /locus_tag="ACHDPO_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFN3367682.1"
                     /translation="MITLYNKTESNFNHNGLAVLDGNILNPVVSEELNGLFSFEFDYP
                     IHAPHSEELLPEMIVKAPVPELSDQLFRIVERDDALGGFLHIVAHHIFYDLATNFIED
                     TYIVNKNGSGALTQLLGATQFMHRFTGTSNISAVNNVRLVRLNPVEVLLDSDLENGFQ
                     SSYGGEIVRDNFTISMLTTRGSNNGVQIRDKKNLTGYKADVDYSGIVTRIMPQGYDGL
                     FLPEKYVDSPNINQYVQPKIKVIKYDNVKVGDEEDEFTQAEAYDELRRLAGLEYSANK
                     VDLPKATYDVEFAPLERTEEYKDFAQLETINLGDTVSVIHAEDGLNITARMVSYKYDP
                     FLKAYISVTLGNITPKFTDVAKDINRVDNKAEQAKDDANYALSSANGKNTNFYGPTTP
                     NNPKLGDVWYKENGDKFEMWVYEIRDGVTQWYPLMTDMTAEEVKQAVEQAQKDANTAT
                     EKANQAFNDAVNALNAAESVGASVETLTTSVEQNTSKISLVASGMSTLEGRVITAEST
                     LTVQAGQIASKASQSTVDNLTGRITTAESTITQNADRFELSLSKTNKAVNVLAGMSIA
                     DLQWAVGGLNTNDGKENTYGGYVRSGFTRVRNGEKYLLQTFVGGKLYSTYATAYLLYY
                     KEDKSFLSYTQFGNTTTPLTVPSSAAFIRIRLTTSDAPETISCYMLKTDVTNGYVDLS
                     EISNVVKLTATTDALLLSVSETKEAIGVPFKVNQWEQGSLSTTDGSEVSATNYLRSEF
                     LDVKVGDKYIGQLRDGTQAAFYYHYYGMDLPYIDFVPTAKQFSETLTAGTYTNATIAS
                     YLVSKNVESMSITSGVTTNPYSNSGDYLVIYKLPLEGKVAPSVISWNGRKDTSDNIVL
                     LYTGGAWEQISTVTSSSNATYSWTLTAEQISGITTDSVYLAFFSVKTGTYAGIYNSSN
                     TPFTLNPSDGSSYHQISYTGSSGAITVPSGTLKMRVRVNTSIKPDEYEGNIYPTTTRQ
                     DYTNANTLYSAILMQKDLINLRVGKGDVINQINISPESILIAGNKVHITGQTTIDSAV
                     ISSAMIQNAAITNAKIADATIQSAKIASIDAAKITTGTLSAARIGANSITADKIAANI
                     LTALTASSSIRITGTTIGYYSGSTLVTEINSQGMTIRRGGTTVGTIGANNISGHSDWR
                     GLVFDLEYGTEYMSWAHKDSSSASVYTQKLSWYARTLQSGMEKGFHFDDDIYLPSMLR
                     IGTQHQISVGGITFSSSLYTKIGSSSGSAGIAFNGSNLMLGDDGKWVDFGVIREICAK
                     LAGRTIALPTGFSSNGTASGWYNPQSFNSMTTYS"
     gene            complement(14592..15284)
                     /locus_tag="ACHDPO_000013"
     CDS             complement(14592..15284)
                     /locus_tag="ACHDPO_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFN3367683.1"
                     /translation="MNAFILDGTINSRTDLGLRITEVPVIPVTERVIDSIEIDGREGD
                     LTILKGWKDVTFGFKVVIWKSDVWTSWQIILPQILNAKTIAFSNEPNVFYPIKYAKAS
                     GLTQILSSMWEFEMELTCSPFRYKTNVATINRTTSGTVNNPGNIYSLPKIKVYGNGTR
                     TLTINGKPIVLNLTNGNLTLDSDLKECFYGDVAANQYMTGDFPEFRVGSNTVTLGTGI
                     TKVEIEPRWRYL"
     gene            complement(15361..15762)
                     /locus_tag="ACHDPO_000014"
     CDS             complement(15361..15762)
                     /locus_tag="ACHDPO_000014"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367684.1"
                     /translation="MLKHKFKAKKPALIGYILLLAIGLFLTAVRWYSGINHGFVFINN
                     QINSHISNFALSFLFYLVIGYLWLLMGTNLRVLTAMGAGLIVANIVCETMMTFLNTPD
                     LIDAIYGISGVLVVYAYLAITKKIGLEETTE"
     gene            complement(15833..18394)
                     /locus_tag="ACHDPO_000015"
     CDS             complement(15833..18394)
                     /locus_tag="ACHDPO_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFN3367685.1"
                     /translation="MADNFGLKIGVEGEKEFKNSLREINQSFKVLGSEMKLVSSEFDK
                     NDKSISSLSARNQVLNKSIDAQKEKITTLENALKNASDSFGENDKRTQNWTVQLNNAK
                     AQLNNMEREVANNEKAIDAMGTEEVDAAKKTDELGNELKDTGDEAEKSGSKFEKFGGV
                     LKGIGVAMGTVALAAGAAAVELGKQVVSAYADYEQLVGGVDTLFKDASSTVQKNADNA
                     FKTAGMSANEYMETVTGFSAALISSLGGDTKKAAGVADQAVTDMSDNANKMGTDIESI
                     QNAYQGFAKQNYGMLDNLKLGFGGTKSEMERLLQEAEKISGVKYDISNFADVTEAIHV
                     IQTEMGITGTTAKEASETISGSIDGMKSAISNLMAGLGNSSADIGMLIGNVVEQFQNV
                     IKNILPVIQNIVSALPAVVDAIIQALGQLLPTLLEAVTSLFSQVLETILGLLPTLIPV
                     VVQAVLTIVQTLIENLPLLIDAAFQLVTTLIQGLGEALPELIPITVQAIITIVNGLIE
                     NLPLLLDAALQLIMGLAQGLITALPILIESLPQIITGIVNFIISAIPQIIQTGIQLLT
                     SLVTALPDIINAIVAAIPVIIQNIINAVIGAIPQLIDAGIQLLVALIGALPQIITTIA
                     NAMPQIINGITGTLVNNIDKIINAGVKLLVALVQNLPAIISAIVKAVPQIITGLANAF
                     GEYVSTMGTIGKNLITGLWNGIADAGSWLRNKISGFFGGVVDNIKDFFGIHSPSTLFR
                     DEIGKYMAQGIGVGFDKEMTGVSKTMQKAIPTKLYMPSFDIDTDIHAAVDSTFSMLDL
                     GAKVDALTNITSEMLPTLLKAMDIKVVLNDGTLVGKLAPEIDKSLATLNRRRVAY"
     gene            complement(18601..18981)
                     /locus_tag="ACHDPO_000016"
     CDS             complement(18601..18981)
                     /locus_tag="ACHDPO_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367686.1"
                     /translation="MSEERSAKISLGGDEYELILTTKATKEIASHYGGLDNLGEKLLK
                     SENFELALDEIIWLITLLANQSIKIYNLKNTEKKDELTTEYVELMTSPLQLAEYKSAI
                     TEAMFKGTARNIESETDSKNKAGE"
     gene            complement(18991..19581)
                     /locus_tag="ACHDPO_000017"
     CDS             complement(18991..19581)
                     /locus_tag="ACHDPO_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFN3367687.1"
                     /translation="MATIGLDKLYYAPITESATTGEETYGTPAMLAKAISAELSVELA
                     EATLYADDGASEVVKEFKNGKLTLGVDDIGRAVAAVLVGATVDQNGVLISTTEDGGTP
                     VAIGFRARKSNGKYKYLWLYRVKFAVPSTSLATKGDDITFSTPTIEGTVMRRNKLDAS
                     GKHPWKAEVDENDTGVEQTTINGWYTSVYEPDFTAD"
     gene            complement(19584..19925)
                     /locus_tag="ACHDPO_000018"
     CDS             complement(19584..19925)
                     /locus_tag="ACHDPO_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009052882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367688.1"
                     /translation="MNILEELNSLFATLHIPVETGEFSDKAPDKYCVLTPLADRFDVY
                     GDNFPTVDVQEVRISLFVKGNYLNTQKQLVQNLLKHEFTITERLFVGFEKDTNYYHVA
                     IDVAKHYEMEV"
     gene            complement(19922..20353)
                     /locus_tag="ACHDPO_000019"
     CDS             complement(19922..20353)
                     /locus_tag="ACHDPO_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003516027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFN3367689.1"
                     /translation="MAKALMKMPEDFLLKVSKLENKTDEIIPKVLESGAEVVEGKVRS
                     NLTAVVGSNTKVPSRSTGELESALGITQARQDKSGNWNIKVGFDEPRIDGSSNAKIAN
                     ILEYGKHGQPAKPFLKPAKSQSRKSCIETMKSKMESEVNGI"
     gene            complement(20346..20684)
                     /locus_tag="ACHDPO_000020"
     CDS             complement(20346..20684)
                     /locus_tag="ACHDPO_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFN3367690.1"
                     /translation="MSFGKMNQRIQIVKVTNQKDSAGFSVKQDEVLAAVHAYKEEKNA
                     TEKWVNMATFSSATCLFRIRYIPNLEVTTEMVVISDQKRYQIVSVENVRNRNMYLEML
                     TTEMEVSADG"
     gene            complement(20681..20992)
                     /locus_tag="ACHDPO_000021"
     CDS             complement(20681..20992)
                     /locus_tag="ACHDPO_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFN3367691.1"
                     /translation="MSDLLNKVKANLILEHNEDDELLERLILTALSYAESYQHIESGY
                     YSEHEMPPTTEQAVIVLASNFYESRDGSTGGFFADNVNASKQVWETVNLLLRLDRRWQ
                     V"
     gene            complement(21003..22214)
                     /locus_tag="ACHDPO_000022"
     CDS             complement(21003..22214)
                     /locus_tag="ACHDPO_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFN3367692.1"
                     /translation="MNKIQELMEKRAQAWNGAKAFVEAKQDKDGLMSEEDAKTYAEME
                     TKVKNFTMEIERMQSMEAMDRELEKPMSQPLTSQPMTTENKMEPKKTGRASAEYKEGV
                     LEALRSNFRHVSNVLQEGVDTAGGYLVPEEYDSRLIDGMTSENIMRTLATTITTSGEH
                     KINIAGSKPAASWIEEGGELSFGDATFDQILLDAHKLHVAIKVTDELLYDNAFNLENY
                     IIDQFTKALANAEEDAFLNGDGVGKPLGIFAATGGGQVAITTNTQSAVTADDVVNLVY
                     ALKRPYRKNAKFIMNDQTISLLRKLKDNNGAYMWQPALVAGEPDRLLGYPVYTSEFVP
                     TVKAGAPVIAFGDFSYYNIGDRGVRSFDQLRELFAGNGMVGFLAKERVDGKLVLPEAV
                     QILKMKASASS"
     gene            complement(22218..22973)
                     /locus_tag="ACHDPO_000023"
     CDS             complement(22218..22973)
                     /locus_tag="ACHDPO_000023"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFN3367693.1"
                     /translation="MKKFWKWKNQTVLNQDNQEEILERTLYLNGPIAEESWFDDEVTP
                     QIFKDELNSGGGNVTVWINSGGGDCVAAASIYNMLADYKGKVTVKIDGIAASAASVIA
                     MAGDKVLMSPVAMVMIHNPSAVAFGEKVDMEKAIAMLDEVKASIINAYERKTNLSRVQ
                     LAHMMDAETWMDANKAVHLGFADEIIGEIDPDIPVNNSMYSEVKVTNSLTSAIAKKCR
                     IEPPEPKEREEINNTIPADSLMSRLNLMKNWRN"
     gene            complement(22873..24201)
                     /locus_tag="ACHDPO_000024"
     CDS             complement(22873..24201)
                     /locus_tag="ACHDPO_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFN3367694.1"
                     /translation="MGIIKSLFKSRDKPTNQTIMNPYRFMFGGSSAGKSVTEQTAMQM
                     TAVYSCVRVLSEAVAGLPLHFYQYRDAGGKDKAMKHSLYFLLHDEPNSEMTSFVFRET
                     LMTHLLLWGNAYAQIIRNGKGEVVALYPLMPDKMTVNRDDNKEIYYLYQADVGQVRLS
                     KADVLHIPGLGFDGLVGYSPIAMAKNAIGLAIATEEYGSKFFANGANPGGVLEHPGTL
                     KDPGKLRESWNATFGGSSNAAKVAVLEEGMKYTPISMSPEQAQFLETRKFQLEEIARI
                     FRVPLHMVGDLDHATFSNVEHLSLDFVKFSLSPWLNRWEQALNKSLLSRDEKEKYFIK
                     FNVDGLLRGDYATRQQGYATGIQNGFLSPDDVRELEDLNPIPGGAGAKYYFNGNMLPI
                     EQAGAAYGVNKEESEEQDEEVLEVEESNGSESRQPRGNPRENPLPQRTNR"
     gene            complement(24267..25001)
                     /locus_tag="ACHDPO_000025"
     CDS             complement(24267..25001)
                     /locus_tag="ACHDPO_000025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367695.1"
                     /translation="MNEYLIQVAPDKISSDPDNTLISRLFYRKWWGKILTEDLTKYAE
                     GIGNYRGETIISFNTIAGATIRLLKCYNQKNFSMPDSHYGRLKVILYSDDITEEMKVK
                     FVKFYDLSHTLANFMPLYVSKPSLNGVKGKGPYHDFPDLFYSDVRDKRYGSSTNADKF
                     IVNNKDYFSKFKDWKSFIELNYLQDFFDDEDYMTFKKLAPSSSFFPYQRKSLTPDEKS
                     KCLEEVNTFLNNAIEIILSRGSRFYI"
     gene            complement(25057..26622)
                     /locus_tag="ACHDPO_000026"
     CDS             complement(25057..26622)
                     /locus_tag="ACHDPO_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFN3367696.1"
                     /translation="MDKDSHYDKSRADYAVAFIELLKHTKGQWFGKPFKLMPWQEKII
                     RDLFGTIKANGYRQFNTAYVEIPKKNGKSELAAAVALLLTCGDGEERAEVYGCAADRA
                     QASIVFDVAVDMIRQNPALSKRVKILTSQKRIIYQPTNSFYQVLSAEAYSKHGLNSSA
                     VVFDELHAQPNRKLFDVMTKGAGDARTQPLFFLITTAGNDTNSICYEQHQKALDIIEG
                     RKHDKTFYPLIYGIKQDDDWTDPEVWKKANPSLGITIAEEKVVAACDSAKQNPAEENS
                     FRQLRLNQWVKQAVRWMPMDKWDACSFNADEESLRGRVCYGGLDLSSTTDLTSFVLVF
                     PPEDEDDKFVILPYYWVPEDTLDLRVKRDHVNYDLWAKQGYIQTTEGNVVHYGFIEKF
                     IEELGEKYNIREIAFDRWGAVQMVQNLEGMGFTVVPFGQGFKDMSPATKELMKLTLEQ
                     KLAHGGHPVLRWNMDNIFVRTDPAGNIKADKEKSTEKIDGAIATIMALDRAIRCGNDN
                     GASVYDDRGLLFL"
     gene            complement(26705..26848)
                     /locus_tag="ACHDPO_000027"
     CDS             complement(26705..26848)
                     /locus_tag="ACHDPO_000027"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367697.1"
                     /translation="MMDYQIYMPDNEDGIEEGYYDWQELVQLLRDNKNNPEAIQFIAD
                     MME"
     gene            complement(26845..27021)
                     /locus_tag="ACHDPO_000028"
     CDS             complement(26845..27021)
                     /locus_tag="ACHDPO_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5049 domain-containing protein"
                     /protein_id="HFN3367698.1"
                     /translation="MNAKIKQQIIEIAESGLTNMFDAIAVQRIAHDRHFYELVIFIEE
                     HKDEYSRFILEGDK"
     gene            complement(27005..27199)
                     /locus_tag="ACHDPO_000029"
     CDS             complement(27005..27199)
                     /locus_tag="ACHDPO_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367699.1"
                     /translation="MKVSKRKIYNIAKNYIVQLPERGDLKAHNSDREDFLDIAVWCLE
                     DALIAAYEAGRKDGQNERKD"
     gene            complement(27201..27578)
                     /locus_tag="ACHDPO_000030"
     CDS             complement(27201..27578)
                     /locus_tag="ACHDPO_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4314 domain-containing protein"
                     /protein_id="HFN3367700.1"
                     /translation="MFPTHEQIEGMKKRYPEGSRVELIKMNDPHAPAKGTQGTVTGVD
                     DIGSILIQWDNGSTLNAVYGEDVVHIIKPDFELVFQNGRREGFETFNDAWQYVTDMIL
                     NHDLVWVDLESKTEDTIYIRKGL"
     gene            complement(27652..28887)
                     /locus_tag="ACHDPO_000031"
     CDS             complement(27652..28887)
                     /locus_tag="ACHDPO_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HFN3367701.1"
                     /translation="MNTTERFEKVDIDKLVPYARNARTHSKDQVKQIQASMREFGFIN
                     PVIVDKDYNLIAGHGRILAAKEEGIKQVPCVFVEHLTEAQKRAYILADNRLAMNAGWD
                     DEMLAVELSDLQGEEFDLDLLGFETDELDKLLNGNDDAQDDDFDVDEELEKPAFSKTG
                     DLWLLGRHRLVCGDSTKPETYEKLMDGKLANLVVTDPPYGVSYQGKAGTIKNDNLKDE
                     AFYNFLYDAFSCMESVMANDASIYVFHADTEGLNFRKAFVDAGFYLSGTCIWKKQSLV
                     LGRSPYQWQHEPVLYGWKKKGKHQWYTGRKESTIWEFDKPKKNGDHPTMKPIPLLAYP
                     ITNSSLSNCIVLDSFGGSGSTLIACEQTDRICHTIELDEKFCDVIVKRYIEQAGSDAD
                     VSVIRDGKTIAFNDLENPE"
     gene            complement(28887..29669)
                     /locus_tag="ACHDPO_000032"
     CDS             complement(28887..29669)
                     /locus_tag="ACHDPO_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014929977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase N-terminal
                     domain-containing protein"
                     /protein_id="HFN3367702.1"
                     /translation="MIEKVNPQHPDKVADRIAGAIVDLAYAEENNPKIAVEVLIGHGI
                     CHVIIETSTALNLNEISQAINRIAGKIKKDVVIVPQDKELADNQATEIRCGDNGIFRG
                     MPLTDEQLQLSKIARDLYQDHPFDGKYILDGERLIICQSHAKTNELKQKYPNATVNPL
                     GDWTGGPDVDTGATNRKLGSDMADGVTGGGIHGKDLSKADVSVNIYAFLKAQETGMPV
                     ELSCAIGDTEIDGVPYSEIVEVARDYVNELGGFEKLAEWGLF"
     gene            complement(29684..30256)
                     /locus_tag="ACHDPO_000033"
     CDS             complement(29684..30256)
                     /locus_tag="ACHDPO_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006702252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFN3367703.1"
                     /translation="MAKDGTQRGGRRPRSGERSQPLVDKVAAGKKASRMEFDLPDVEL
                     LIGEDIGEGVELEGNDYPEPSAYLSAKQKDGTVLGADEIYNSTFQWLKDRGCETLIAP
                     RMVESYAQNFARFVQCENALSQYGLLGKHPTTKAVMASPFVAMSQNFQKQANVTWYEI
                     QQIVKENASVEYTGDPNTDAMERLLRSKNG"
     gene            complement(30390..30755)
                     /locus_tag="ACHDPO_000034"
     CDS             complement(30390..30755)
                     /locus_tag="ACHDPO_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFN3367704.1"
                     /translation="MPMKPANPCKFPGCPNRTHDTYCDEHKTLARKRYEKYERDPAIN
                     KRYGRAWKKIRARYVAAHPLCEMCLKEGRFTSVEIVHHIKELSDGGTHDENNLMSVCK
                     SCHSKIHMTRRNTKDKTIM"
     gene            complement(30923..31351)
                     /locus_tag="ACHDPO_000035"
     CDS             complement(30923..31351)
                     /locus_tag="ACHDPO_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HFN3367705.1"
                     /translation="MTPKEYLKQAYRLNKRIDDRIKEKAELYQLAVTVSSTTFEEKIS
                     SGTRNTEAPFVRNLEKCYQLEAEIDAEIDKFVDLKRQMRGVIDELTNVDEKIVLINRY
                     LLEESWDKIAEDLHADVRTVFRWHSKALENLKLPDEPIVI"
     gene            complement(31348..32700)
                     /locus_tag="ACHDPO_000036"
     CDS             complement(31348..32700)
                     /locus_tag="ACHDPO_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014929979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2-related protein"
                     /protein_id="HFN3367706.1"
                     /translation="MKFVPHNYQKYAIDFIKDHKTAALLLDMGLGKTVTTLTAIKDLM
                     HDDFTIQRVLIIAPLRVTQSTWPTEIQKWDHLKDLSYSVVLGTPSQRMAALQNNANIY
                     LINRENLDWLINKSGFTFDFDMVVIDELSSFKNLKAKRFTSFMKVRHKVDRIVGLTGT
                     PSSNGLMDLFAEFKVLDMGERLGYYISRYRDKYFLPDKQNGMQIYSWKPREDAEQEIY
                     DKISDITISMKSVDFLDMPELVMNEVPVDMGLKEKQKYDEIKADLVLQLKEATIDAAN
                     TAVLSNKLLQMANGAIYDEFNVSHHIHDQKLDALEDLIEGTNGKPILIAYWFQHDLER
                     IKERFNVRQIKTSQDIIDWNEGSIPIAVIHPASAGHGLNLQAGGSTLVWFGLTWSLEL
                     YQQTNARLWRQGQSDTVVIHHIIAKDTIDEDVMLALKRKDKTQSCLIDAVKARLEGSK
                     "
     gene            complement(32700..32984)
                     /locus_tag="ACHDPO_000037"
     CDS             complement(32700..32984)
                     /locus_tag="ACHDPO_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HFN3367707.1"
                     /translation="MREKQVEQALVKAVKRVGGICPKFTSPGLAGVPDRLVLMPNGKL
                     GFVEVKAPGKKPRSLQLFRMKQLTDLGFQCFVLDEIDQIPELLERIGGDV"
     gene            complement(32981..33190)
                     /locus_tag="ACHDPO_000038"
     CDS             complement(32981..33190)
                     /locus_tag="ACHDPO_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367708.1"
                     /translation="MKFKQWLQIGIGKRDLRFDEFYEFAMSDVTYPWKKSFDKQVAHL
                     MIHCAEKEYLEILRDAYFEYLTVWL"
     gene            complement(33328..35571)
                     /locus_tag="ACHDPO_000039"
     CDS             complement(33328..35571)
                     /locus_tag="ACHDPO_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage/plasmid primase, P4 family"
                     /protein_id="HFN3367709.1"
                     /translation="MLKMTLFTSNQVGNSKNGLFPTKQVVTDKETLVATVKLDHVMAE
                     YKGNYRKGDNFIQSDVIPLDCDNDHSDNPDDWVAPFEVAMQFPDVTFAVSYSRNNMKD
                     KGGKSARPRFHVYFPIPATTDKDEYVELKKQIQSEFPYFDNNAMDAARLLFGTPNSEV
                     EIYEGSKLITDFLEDDLFADWDNAQSEISEGSRNSSMSHIAGKLIKRYGATEDTYHKY
                     LEQSQKCNPPLPEEELKAIWNSAVNFGKKVKQQEGYIPPEQYNSDLSLEPTDYSDLGQ
                     ATVLAREYECKLHYSPSTGYLVYNGSYWEESKPKAQGVIHALTERQLEESETEIEKRT
                     KEMVSNGAFDVLASVGPKKAVTMFNTAQRHSFDLYQHAQEYKKFAVKRRDSKYLSSAL
                     TEAKPMLEIEQRLLDVNEFLLNTPTATFDLRTGKSQDHNSEDYITKQTECAPSDANQQ
                     IWLDALNTIFVGDQELIDYVQMIVGLAAIGKVYVEALIISYGEGRNGKSTFWNVISRV
                     LGNYSGSISADILTSQIRRNVKPELAEAKGKRLLIAAELEEGMRLNTSNIKQLCSTDE
                     IAAEKKYKDPFKYVPTHTLVLYTNHLPKVGAIDKGTWRRLIVIPFLATIDGNKDIKNY
                     ADYLFENAGGAILQWILDGAKKVIAADFHLTVPQVVANAISEYKTANDWLGHFLDECC
                     ETAVDFEEKSGELYAEYRAFCTRTGEYIRSSADFYTALEAGGFKRRRTNKGNKIVGLQ
                     LKSEFLE"
     gene            complement(35564..35908)
                     /locus_tag="ACHDPO_000040"
     CDS             complement(35564..35908)
                     /locus_tag="ACHDPO_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4406 domain-containing protein"
                     /protein_id="HFN3367710.1"
                     /translation="MPRRKDYRTSVYVCSPFSGNVVVNHKNTKRYCRIALDRGYMPVA
                     AHLMYPQFMDDATERDVAMHMSLVLMGKCEEVWVVGDTISQGMAVEIEQAEYWKKHIR
                     YFDDEMKEVSNA"
     gene            complement(35901..36671)
                     /locus_tag="ACHDPO_000041"
     CDS             complement(35901..36671)
                     /locus_tag="ACHDPO_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014929981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HFN3367711.1"
                     /translation="MNELKVFENAEFGSVRTVMIGDVPHFVGKDVASILGYTNPQKAL
                     RDHVDEEDKTVNESFSVNGTMAILINESGLYSLIISSKMPNAKKFKRWVTNEVLPSIR
                     QHGVYATEDFITKSIEDPAWAISVLKQLQEKKEMVAMQQQMILEMKPKVSYYDLILQN
                     NSVMSISKISKDYGMSPQAMNKLLHELGIQYKQGKMWLLYQKYANQGYTQSKTHAIDA
                     ERSVMHTYWTQKGRLFLYDLLKSKKNILPVIERGDNNA"
     gene            complement(36882..38819)
                     /locus_tag="ACHDPO_000042"
     CDS             complement(36882..38819)
                     /locus_tag="ACHDPO_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HFN3367712.1"
                     /translation="MKHLSLDLETYSSVDLSKCGVYKYSESPDFEILLFAYSVDGGPV
                     EVVDLKMDETIPAEILTSLSDETVIKHAFNASFERVCLSRFLGLDGFLNPRGWQCTMV
                     WGATLGLPLSLVGVGAVLGLDKQKLTEGKDLIRYFCVPCNPTKVNGGRTRNLPHHAPT
                     KWSAFKTYNSRDVEVEIAIQGKLSNFPVLDSVWKEYWLDQEINDRGIEIDKDFVEAAV
                     QLDELSKAGLNQQLQELTGLENPNSVLQMRGWLLDHGLETESLGKKAVAELLEQPIDE
                     NLKQVLVLRQQLAKSSVKKYQAMQNFACSDNRSRGLFQFYGANRTGRFAGRGIQLQNL
                     PQNHMSDLSEARSLVKQSNFEMLNILYGNVPNVLSELLRTAFVPREGMKFIVSDFSAI
                     EARVIAWLSGEKWRQEVFKNGGDIYCASASQMFGVPVEKHGVNGHLRQKGKIAELALG
                     YGGSVGALKAMDALEMGLTEDELQPLVNSWRDSNINITELWWAVDKAVKTCVKERRST
                     STHGIKFEYKSGFLFIQLLSGRKLVYVKPKIGENKFGGEAVTYEGVGATKKWERLESY
                     GPKFVENIVQAIARDILCFAMENLRKYRIVGHVHDEVIIEVPMESKVEDICQLMSQTP
                     KWAEGLLLNADGYECEFYQKD"
     gene            complement(38880..39422)
                     /locus_tag="ACHDPO_000043"
     CDS             complement(38880..39422)
                     /locus_tag="ACHDPO_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HFN3367713.1"
                     /translation="MSKTSKVITGTNTRLSYFHGWEPASINGGAEKYSTAVLIPKSDK
                     RTIDTIEKAIDAAIEEGLAKFGGKKPNKAEIKLPLRDGDIERDDEAYQGHYFINANST
                     TAPQIVDQHVQPILDRSQVYSGCYARVSINFYAFNANGNRGVAAGLGNIQFVRDGEPL
                     GSQVSASDEFETLADDDFLA"
     gene            complement(39424..40566)
                     /locus_tag="ACHDPO_000044"
     CDS             complement(39424..40566)
                     /locus_tag="ACHDPO_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HFN3367714.1"
                     /translation="MPTQHAVLSASSSNRWIHCPPSVRLSEHFENKSSPYAQQGTDAH
                     TLCEYKLNKFIGNDVTDPTSTLEFYDEEMEQCAESYATFVMEEVAKAKQTTVDSIVIV
                     EQRLDFSRYVPDGFGTGDCLVIADGTLSVIDMKYGLGILVDAYQNPQMMCYALGALEL
                     FDVIYDIQEVKMTIFQPRRENVSTYTLLKEELLQWAKDVLSPAADLAFKGEGEYQCGK
                     WCGFCPAKNSCRARADHNLKLAQYEFKPPELLSDDEIEEIIGKVDDLVSWSNDIKDCA
                     LKLALGGKQWTHHKLVEGRSTRKYSNDNDVAAAVIKAGYDPYDKKLLGVTAMTKALGK
                     EKFNEILGEYIIKPKGKLTLVDGSDKRQAVTVNNLNEEFKPLTEEQ"
     gene            complement(40567..40881)
                     /locus_tag="ACHDPO_000045"
     CDS             complement(40567..40881)
                     /locus_tag="ACHDPO_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010821424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA biogenesis protein rrp5"
                     /protein_id="HFN3367715.1"
                     /translation="MSKTKLFLQVVEDVQALADSLQELAVAMKTNEPEPQVETPEPTM
                     ETKSEVKQPTLEEVRGLLARKSQEGKSTEVKALIEKYGASRLSDVPTENYAALVADAE
                     GL"
     gene            complement(40886..41092)
                     /locus_tag="ACHDPO_000046"
     CDS             complement(40886..41092)
                     /locus_tag="ACHDPO_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010821423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367716.1"
                     /translation="MNLKHKIRVNVTDDTGNKETVLQGGVRHLPRWFARWLFGKGNMD
                     KILVLTPGDTIESVEIREVNKKGA"
     gene            complement(41189..41806)
                     /locus_tag="ACHDPO_000047"
     CDS             complement(41189..41806)
                     /locus_tag="ACHDPO_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010821422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367717.1"
                     /translation="MSRFMKTHQNDRSTYKYVFERTDANGRIQKEVVEIRPGEDGVTE
                     LNIQELHRADDRAIYNFYKNARPERTEEEKEKIKAWKEKFREDFNNEHGYYPMDEYVD
                     GEANDYFKRNYNLSLNEFDDECDEGDNPIQSLVYDAYQDNEEDPRIDRLREVVTQLLP
                     YHQEIYHMLVTENMSQTEVADKLDKKKQSINRTFGIIKDKIKELF"
     gene            42201..43151
                     /locus_tag="ACHDPO_000048"
     CDS             42201..43151
                     /locus_tag="ACHDPO_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-three component system protein"
                     /protein_id="HFN3367718.1"
                     /translation="MEISEITQTLYPFMGSEYVKPQDFLIALLDSVSNDDEATIFGFS
                     DDNLRRFYNGTRPLTQEYAVRVAGKFNIDKCTTFIYERLIDDAPTVLKQQLIDKGVVI
                     PKDTDVSEIVAHLLLDEITSIASQTKVKTKKAKPKLSELELASLRINTNGDFSYNDEV
                     KKFFDDLPVPLDIRAEEMTYVIALFSAYADADGYEVYEHTNDLPNSRLKDFKRQRRNY
                     YKAESIRRGVRDNFTQEEGTEHFEALKEDMYDGIEEVYEEDYDDGVERLKAVLQQSSV
                     ITLNGSILSFIPGLLQNSAKKGICHMLVNDGKIKWVTEDE"
     gene            43144..43590
                     /locus_tag="ACHDPO_000049"
     CDS             43144..43590
                     /locus_tag="ACHDPO_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-three component system middle component 2"
                     /protein_id="HFN3367719.1"
                     /translation="MNSLFNTPFEISVRVMLLLSEFKEPVSADRILITDFITTYGRDF
                     EISDYNLNGDNSYRFSEFIARRELVKDAVKNLVLQHVIQPSQSKEGFKYALSEDGLKL
                     ISQFVSVYAEKYLQIADESVKYIQDKSDVELLRQINQRAKEFKGEQ"
     gene            43593..45425
                     /locus_tag="ACHDPO_000050"
     CDS             43593..45425
                     /locus_tag="ACHDPO_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010821419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3367720.1"
                     /translation="MQNYYIERVTIKGKDREDATVKFTNGLNIISGPSNTGKTSIVTA
                     IDFLYGAKKDAAPFSTDATGYSKVELIIQSTNGKYSLTREFDSNSILVSKITSSGEYV
                     DYEKYNARSGKNPISHFWLQLLGIDDDYQIIKNEDFKRQKLTWRTLAPSTLIPQDRVN
                     TSASVLFPGETTQRTAFLSSLLLLLYGSDFANSEENETKEHKKIRRNSVINYINSSLS
                     ELYENYEVAKSELPEAPSDDFQQIVDGMFAELETIEKQINDALASSKILIKEIYQKEQ
                     YLHETQLLLNRYKQLHYQYQSDIERLTLIVDGERLLNDHNEHDTSHSCPFCNGELSKP
                     VQTTYIDTARSELHSLLSQLSDLTEESHDTEVELQELMEQLDELKTRKKSLDAAINDE
                     LKPKAETLKDRINKIETYRDIKQQLISMEKMQNKLKSDLEKIENEPEDERILYKPKEK
                     FDAEFYKEMSELLDSMLRNMHYKPNEFRNAFFAKDIFDIKINGNLKWTENGHGYTAFI
                     NSVVVMAYRHLLYNHAKYTPSVFIIDSPLLGLDERKKQDGDDNMKEGLFKYFMDHQNE
                     GQLIIVENTTNLPALNYDDKQVNQIVFTEDKNNGRYGYLYDIYN"
     gene            45441..45644
                     /locus_tag="ACHDPO_000051"
     CDS             45441..45644
                     /locus_tag="ACHDPO_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3367721.1"
                     /translation="MKFSYNPLWKLLIDRGLNKAQLRKMTDISSATLSKLNKGENVTT
                     DILLRICEALDCDLSDIVEIVRD"
     gene            complement(45695..46831)
                     /locus_tag="ACHDPO_000052"
     CDS             complement(45695..46831)
                     /locus_tag="ACHDPO_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFN3367722.1"
                     /translation="MANSLDSIFEDDAFDDLTKQVEKKKVVKQDPEVAKFQEIIDFVN
                     ENGREPEKTPEWSSERALWARLSGFRGKPERSEKVKKYDTLGLLEKEFEPDGEFLADS
                     VEIDDELNLDDILGSDDMIDDFSDLLDVSRYRRTVNAADKIGRRKHASHFEKYKSLFD
                     QVHADIASGRRKIIPFEQYDIHENRFYIQNGVMMYIVSISKDTFIADNGKTNARMHVV
                     YENGTENKNLLLQSLASSLYSTERHGRMVTEPVDEETLAESFGEEFTTGYIYVLKSLS
                     TNPDISKWNNLYKIGFTRNDVESRIANAENDVTYLNAPVKVMLSAEVQNVNAQLLERT
                     LHHVFQDKQVVFQDGNFKKATEWYMVPLNDIESKINEVIAGLQK"
     gene            complement(46821..48776)
                     /locus_tag="ACHDPO_000053"
     CDS             complement(46821..48776)
                     /locus_tag="ACHDPO_000053"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010821418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFN3367723.1"
                     /translation="MTSNLFEINFDKNQSKTTNDLGMREMQERVYEKRASQYLLVKSP
                     PASGKSRALMFVGLDKLHNQGIKKVVIAVPERSIGKSFKDTELSKFGFYWDWEVKPSD
                     NLTIGGGEKSKVQHFVKFMNSTDPSDNILIATHATLRFAFEELDDSLFDNTLLAIDEF
                     HHVSRDDKSVLGNALRSIMSNSNAHILAMTGSYFRGDSVQILEPADEDKFDKVTYTYY
                     EQLEGYKYLKSFAMGYSFYRGKYTDALDKVIDVNKKSIIHIPNVNSGESTKDKYAEVD
                     EILDLLTDGGNITQNEDGIYEIERPDGKKLLVADLVNEEGREKVSAYLASITDDIKDL
                     DKLDIIIALGMAKEGFDWPFAEYALTIGYRNSLTEVIQIIGRVTRDSPNKTHAQFTNL
                     IAQPDAQDDEVLFAVNSIMKAISASLLMEQVLAPVYKFKPKDGKPDKPGDLSIRGLKP
                     ADTTERTKKIIENDMEDLKSSILQSQDIQNAIVSGADAKMINKTLIPRVIIDRYPDLT
                     NEELETVRQHTVADINIAAGRTTTSEDGSREIIKMADRFINIDELNIDLIDQVNPFQR
                     AYEVISRDIDAPTLRFIQDYLSSNKYDFTDEQLVAAYQAAKKFRAENGRNPDRNSKDD
                     GEKYLAFALLRLAEIKREREAAKEDGE"
     gene            complement(48769..51486)
                     /locus_tag="ACHDPO_000054"
     CDS             complement(48769..51486)
                     /locus_tag="ACHDPO_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010821417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HFN3367724.1"
                     /translation="MAKNKVLNITEIEDGVKKILSNRGDDFITQFLSLYDIPKTSITR
                     AKSKFDNGEPFVIKNKLHYEEIEGNVVIAIDAIAQSIKEQKSKPRYILVNDYLDIAAI
                     DTKTHETLNIPIEELPANADFFLAWNGIEKADYQAENPADRKAAERFAKLYDVVAKDN
                     PDANEHAFNLFLIRVLFLLFAEDTGIMNKGSFTNVLKTRTAEDGSNFNEVIKELFAIL
                     DINELARNGKDEWLLEFPYVNGKLFGEPHVDLTFSKVSRELLIEAGELLNWNEINPDI
                     LGAMIQSVASAEDRHVAGMHYTSVPNIMKVIKPLFLDDLTESFETLKLRSEENELKDI
                     TEKTRNDNKRTIINDLSALLTRISNIKFLDPASGSGNFLIIAYKEIRRLEIKILQLLG
                     DLQNNDSMPLSVIHLGNFNGIELDDFAHEVARLSLWIAEHQMNKELEEAIPGTIAELL
                     PLKDAGNIVCANSLRIDWNEVLRLKENHEIYIMGNPPYLGKSLQNAEQREDMEKLVGD
                     IRKYKLLDYIFGWFWKAKQYIATSHGSFAFVTTNSICQGEQVSILWPYLLKDEVRISF
                     AYQSFKWNNNAKNNAGVTVVIIGMTNNVNIHPKLYLENGSVMSVSNINAYLANGENVF
                     VNESRNSISNLPSLKFGSMANDGGNLVFSVAEYWNLIQKYPDIKHLFKKYLGSTGLIN
                     GDLRYTLWLTEEDATRYKQNSLIKETIKNVKSYREKSKRKETRALAEKPWSFGEVRYD
                     ETSENSILIPRVSSEKRDYVPMGIVGSDTIISDSAMAIYNAPMWLLGLLESRMHMVWL
                     RSVGGKLETRYRYSAGLVYNTFPIQDLSAQRKNEMTRVMTEILDLREYEGGTLADLYN
                     KDSMPESLRKKHQELDGIVDRAYQQRPFESDEDRLGTLLKLYQEMTIND"
     gene            complement(51487..51708)
                     /locus_tag="ACHDPO_000055"
     CDS             complement(51487..51708)
                     /locus_tag="ACHDPO_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3367725.1"
                     /translation="MSISYNKLWKLLIDLNMNKTQLREISGVSPNVIAKLGKNELVAM
                     ESLLKIAAALNVDVSEIISSDVIDAEDVK"
     gene            complement(51857..52693)
                     /locus_tag="ACHDPO_000056"
     CDS             complement(51857..52693)
                     /locus_tag="ACHDPO_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFN3367726.1"
                     /translation="MKQIFIFSDTQKDNISYFEREPAILVSMSRSDLPYLKEQDFSNY
                     PAVYVLIGGNKRYVGQAAGQSISLRLSQHFLKEYKAWVESVLFFTRADGKMSKADTDY
                     LEKRLIQDFQEKSDYEMMNSTAGNTSYIDKLQKAKSDQLYDTVFEIIDEIANIDLFGT
                     SEDSETQIYEFSSSGQYEIEYDGKKISSKSARGLLVDFVSQLFADGNYNNQLQELIVD
                     ETPSFAIILGRKPSMYNGRPNSARVADGVWVYANFNKKNVRIKIDKLARQLGIPVKIK
                     WN"
     gene            complement(52902..54278)
                     /gene="rlmD"
                     /locus_tag="ACHDPO_000057"
     CDS             complement(52902..54278)
                     /gene="rlmD"
                     /locus_tag="ACHDPO_000057"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFN3367727.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIECV
                     GLLTRVER"
     gene            complement(54389..55444)
                     /locus_tag="ACHDPO_000058"
     CDS             complement(54389..55444)
                     /locus_tag="ACHDPO_000058"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFN3367728.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(55454..56884)
                     /gene="gatB"
                     /locus_tag="ACHDPO_000059"
     CDS             complement(55454..56884)
                     /gene="gatB"
                     /locus_tag="ACHDPO_000059"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFN3367729.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(56881..58353)
                     /gene="gatA"
                     /locus_tag="ACHDPO_000060"
     CDS             complement(56881..58353)
                     /gene="gatA"
                     /locus_tag="ACHDPO_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFN3367730.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(58353..58658)
                     /gene="gatC"
                     /locus_tag="ACHDPO_000061"
     CDS             complement(58353..58658)
                     /gene="gatC"
                     /locus_tag="ACHDPO_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFN3367731.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(58764..60800)
                     /gene="ligA"
                     /locus_tag="ACHDPO_000062"
     CDS             complement(58764..60800)
                     /gene="ligA"
                     /locus_tag="ACHDPO_000062"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFN3367732.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(60817..63051)
                     /gene="pcrA"
                     /locus_tag="ACHDPO_000063"
     CDS             complement(60817..63051)
                     /gene="pcrA"
                     /locus_tag="ACHDPO_000063"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFN3367733.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            63206..64765
                     /locus_tag="ACHDPO_000064"
     CDS             63206..64765
                     /locus_tag="ACHDPO_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFN3367734.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(64876..66807)
                     /locus_tag="ACHDPO_000065"
     CDS             complement(64876..66807)
                     /locus_tag="ACHDPO_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFN3367735.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(66825..67739)
                     /gene="pfkB"
                     /locus_tag="ACHDPO_000066"
     CDS             complement(66825..67739)
                     /gene="pfkB"
                     /locus_tag="ACHDPO_000066"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFN3367736.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(67736..68488)
                     /locus_tag="ACHDPO_000067"
     CDS             complement(67736..68488)
                     /locus_tag="ACHDPO_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFN3367737.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(68647..68856)
                     /locus_tag="ACHDPO_000068"
     CDS             complement(68647..68856)
                     /locus_tag="ACHDPO_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367738.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(68867..70195)
                     /locus_tag="ACHDPO_000069"
     CDS             complement(68867..70195)
                     /locus_tag="ACHDPO_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367739.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            70331..70486
                     /locus_tag="ACHDPO_000070"
     CDS             70331..70486
                     /locus_tag="ACHDPO_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFN3367740.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(70560..71147)
                     /gene="yihA"
                     /locus_tag="ACHDPO_000071"
     CDS             complement(70560..71147)
                     /gene="yihA"
                     /locus_tag="ACHDPO_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFN3367741.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(71230..72480)
                     /gene="clpX"
                     /locus_tag="ACHDPO_000072"
     CDS             complement(71230..72480)
                     /gene="clpX"
                     /locus_tag="ACHDPO_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFN3367742.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(72727..74016)
                     /gene="tig"
                     /locus_tag="ACHDPO_000073"
     CDS             complement(72727..74016)
                     /gene="tig"
                     /locus_tag="ACHDPO_000073"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFN3367743.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(74170..75102)
                     /locus_tag="ACHDPO_000074"
     CDS             complement(74170..75102)
                     /locus_tag="ACHDPO_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367744.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(75259..75918)
                     /locus_tag="ACHDPO_000075"
     CDS             complement(75259..75918)
                     /locus_tag="ACHDPO_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFN3367745.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(75921..76946)
                     /gene="sppA"
                     /locus_tag="ACHDPO_000076"
     CDS             complement(75921..76946)
                     /gene="sppA"
                     /locus_tag="ACHDPO_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFN3367746.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(76959..77249)
                     /locus_tag="ACHDPO_000077"
     CDS             complement(76959..77249)
                     /locus_tag="ACHDPO_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367747.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            77659..79464
                     /gene="glmS"
                     /locus_tag="ACHDPO_000078"
     CDS             77659..79464
                     /gene="glmS"
                     /locus_tag="ACHDPO_000078"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFN3367748.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(79536..80891)
                     /gene="glmM"
                     /locus_tag="ACHDPO_000079"
     CDS             complement(79536..80891)
                     /gene="glmM"
                     /locus_tag="ACHDPO_000079"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFN3367749.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICARYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(80915..82084)
                     /locus_tag="ACHDPO_000080"
     CDS             complement(80915..82084)
                     /locus_tag="ACHDPO_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFN3367750.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(82081..82968)
                     /gene="cdaA"
                     /locus_tag="ACHDPO_000081"
     CDS             complement(82081..82968)
                     /gene="cdaA"
                     /locus_tag="ACHDPO_000081"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFN3367751.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(83157..86837)
                     /gene="nifJ"
                     /locus_tag="ACHDPO_000082"
     CDS             complement(83157..86837)
                     /gene="nifJ"
                     /locus_tag="ACHDPO_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFN3367752.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            87035..87556
                     /locus_tag="ACHDPO_000083"
     CDS             87035..87556
                     /locus_tag="ACHDPO_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFN3367753.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(88255..88820)
                     /locus_tag="ACHDPO_000084"
                     /pseudo
     CDS             complement(88255..88820)
                     /locus_tag="ACHDPO_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(88999..89655)
                     /locus_tag="ACHDPO_000085"
     CDS             complement(88999..89655)
                     /locus_tag="ACHDPO_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367754.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(90223..91158)
                     /gene="whiA"
                     /locus_tag="ACHDPO_000086"
     CDS             complement(90223..91158)
                     /gene="whiA"
                     /locus_tag="ACHDPO_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFN3367755.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(91192..92190)
                     /gene="yvcK"
                     /locus_tag="ACHDPO_000087"
     CDS             complement(91192..92190)
                     /gene="yvcK"
                     /locus_tag="ACHDPO_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFN3367756.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(92187..93071)
                     /gene="rapZ"
                     /locus_tag="ACHDPO_000088"
     CDS             complement(92187..93071)
                     /gene="rapZ"
                     /locus_tag="ACHDPO_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFN3367757.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(93206..93937)
                     /locus_tag="ACHDPO_000089"
     CDS             complement(93206..93937)
                     /locus_tag="ACHDPO_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFN3367758.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(93941..95206)
                     /locus_tag="ACHDPO_000090"
     CDS             complement(93941..95206)
                     /locus_tag="ACHDPO_000090"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFN3367759.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(95469..98285)
                     /gene="uvrA"
                     /locus_tag="ACHDPO_000091"
     CDS             complement(95469..98285)
                     /gene="uvrA"
                     /locus_tag="ACHDPO_000091"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFN3367760.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(98295..100289)
                     /gene="uvrB"
                     /locus_tag="ACHDPO_000092"
     CDS             complement(98295..100289)
                     /gene="uvrB"
                     /locus_tag="ACHDPO_000092"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFN3367761.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            100548..102050
                     /locus_tag="ACHDPO_000093"
     CDS             100548..102050
                     /locus_tag="ACHDPO_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFN3367762.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            102052..102789
                     /locus_tag="ACHDPO_000094"
     CDS             102052..102789
                     /locus_tag="ACHDPO_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFN3367763.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
BASE COUNT        28528 a        22904 c        18251 g        33364 t
ORIGIN      
        1 tactttccac aaaataataa tcttccaaaa cgattgactg accatcttgc tcaacatctt
       61 tagcagatat tttgctgcat ggaataatct gaatacgttt taatgaacta acattcttac
      121 tattgtcatc tatcgtagat aataccgcag ttttgatatc atcaatctct tttttgaaat
      181 cctcagaata atcttccaat aactcaaatg tttccaattt taaatttgtt ttgaagcgtt
      241 caaccccaag ccattcatat atcgtagttg tactagcttt ttcaggcacg taaataaaac
      301 gcatttgttt ttctattgat ttaggcagtc gcttatcagc ataccttaat tctttgtttg
      361 gataaaagaa gccatctttg gctaagactg ataatccttc ggtagaataa gtaggattca
      421 ttcctttttt atttcttata agttcattat ataatctgcg acttatttcg cctttatcga
      481 attttggtaa ctcaactaat atagctctta tttcatcatc cgaaaacatc gccatatttt
      541 ttctgaaatc caactgttca acaatgcgtt gccccaagag ttccattaag ctttgttcag
      601 aaactccata caatcccgga acgtgtgcct ggagcttttc atatagcaca atttgtctcg
      661 ggctatattt ttctccatca atcttaatcc atgcagtttt attcaaaatg tatttcacat
      721 actcatttga attaaagtac aatccactcc agttcgattg ctgacttgca cttgattctt
      781 tttttaccga agataataaa tctgtcaatt cttcgtcttg attgagccaa ttgacaatgt
      841 ctttcgtatc taatttgtct attaattctt caaaattact gatgtactta gaagttaaat
      901 aattaatatt cgtaaatttt atttcattct tatatttgtt ataaataaac tttttaaatc
      961 caacatcatt ttttaaagaa tcgttatcat aaatcttagg atatttggaa acaccacatc
     1021 gaagaataaa tgacagaaaa tctctctcct cagcaaaact agagcaatct atttttttca
     1081 atgccgtgta atctgtatct tgaaaaagct tatctcctaa ttcattgcca tactcttttc
     1141 caatatacat tttattggaa ggttgaacgt caccagcaac gtttggaaga ttaaatggaa
     1201 ctttagacag ctcacttcca gctgatagtt tttcattgta gttatcataa aaccaattaa
     1261 tgaaactgat agatttttca acagtgtcaa tttgtcgatt aatcgttcca atgatcaaat
     1321 ctgaactgct ttgctcagtg aattcaattg caagatattt ttcactgaat gcatctagaa
     1381 tacgtttatc tcctgtacgt tcagctttgt atgcattagc tgtttcttcc catttatttt
     1441 tccaacttga tgaagtctta atctgataaa ttaactcatc aacatatgtt tgtttcaaaa
     1501 tgcttaaact aacccaagaa gacagctctt ttggaagcac agtaacacct gtatcggtcg
     1561 gtaagaatac cttatctgat ttcatcaacc aattgtcact attgtccttt aatagcttag
     1621 ggacaatcgg agaactttta tattgctcac tccaccataa gaacactttt gtccttattc
     1681 tattttccca agaagatgaa agaatgttga ttttatcaga tagttcatct acaacaaacg
     1741 acaggccagt gtattcatta taattagcaa gttcttgtac tagttggtca ttttcgtttg
     1801 tttctaataa ttgcaacaag gtggaaaatg tctcacctat tagctcctca gggaattctt
     1861 gaaggaaaag ttttggatta tctttgatag aaatatattg ccaattgaca gtcggtagta
     1921 tttgggcatt agataaaata cccaagaatt cgttcattaa gtcaaataca tctaagtccc
     1981 atagtttatt ctctttaaaa ggagttacca tttttaatgc tatgtcttca tattcaggct
     2041 tagataattt ttctgctact tcagaaataa atttgagcac ctcaataaat attttcttat
     2101 ttatttgttc actatcatcc gggacgtcat cacgtgaatt atttgttata aacggtgcat
     2161 ttataagtgc atgaattggt gtaccaaaat tacgtactgg aaagtagcaa tatagttttt
     2221 ctttggagta atcgtaatca gaatctttag aaacggctag tgcaatttta gcaactttat
     2281 ctcctatcat agattctttg tcaaaaacaa aatattcttc agacggtgat tgaccagtaa
     2341 catcactttt ttctatcaat acatcatttc catccacaat tttctctgat attttttcat
     2401 catcagttgt ttcaataaca atttttgtta tatttggtaa aaataacagt gacttataaa
     2461 atggctgctg aagttgttta gaaacactcg tgcctttact taaattagtt tcttttagtt
     2521 ttactcgaat taatgtatca aaaccagaat caattttgtt tattggttga ggacagttca
     2581 ttattggaaa acataaatca taatcttctt ttttccaatt tttcttctgc tcaaaaatta
     2641 attcactgaa tttgtcagaa tctcttgata catactgctc aaaaagcttt tttgtgaatt
     2701 cttcactaaa tcgaatagca aattctcccg aatacagttc gacccactca gcatcgttta
     2761 gcaaggaacg aaaaccagtc cccttatttc cgatattttg tgatgattta ttactcgctc
     2821 ttcctaagca caatctttca attgtatctt ttgaaaatga agtgcctgta ttcccaactt
     2881 ccaagatatt atttttatat gttatctgaa ctttcacttc gtcattgcta gcatcatttt
     2941 ctgattttat atctccatag gcatcgtcta cattctgtaa taactctaaa atctgacgcc
     3001 cattataatc acgcatcaat tcatattctt cgctgcaggc cttttcaagt tcattactca
     3061 actcagaatc cgtatattta cgaataaaaa tatcccttaa ttcatcaatg gtattccatt
     3121 ggctcacaga acttcgcccc cagcctattt tttacataat atattatatc atcaatcact
     3181 ttatgaaatc caatcaataa agacgttaat atggctaccc acattaacgt ctagtcctat
     3241 ctattcaaat taaatttcta cagtcactct caccccactt ttgaaatcaa caacaatgtt
     3301 cttttcaaaa atggtgacct tctcaatcaa ccttcgaaca agcacttcat tatactcatt
     3361 gatgacatcg tgttctttta caaagactac catctcatca acccgttgtt gcaaattagt
     3421 attcgctgct atttgttttg caaccgcatc tcgttcatct cttagtgaaa atatttggct
     3481 tgccaattca tcgtaaccct gaccgccaac tgccaggcta ataatttcag cttcaagctc
     3541 tttcaactga ctgtctagtt ctgccaatcg gtcagttaat ccatcagtca taactgagtt
     3601 gatattgtca tttaattgct gaagaaaagc atcacgatcg attaacgttt cattgattgc
     3661 cttgataaca gctccatgca ggtctgtttc gtagattgtt cgacccgtgc aattatgttc
     3721 tcgtttatcc actctggatt tgcatcgcca cacagttcct cgattcttcc aatgaactct
     3781 gcggtaagca ttgccacagt caccgcaaac tgtgatacca gataacgcat acttcccaga
     3841 aaagcactgt gactttttgt ttttcattga tttacgccgg tctagttctt gctgggcttg
     3901 catgaagata tcttttggga taatggccgg atggctatct tcaacataat actgctgagc
     3961 gtaactcccg tcattcttca ctcgtttctt tgtcaagaaa tcggtagtat atgttttttg
     4021 aagcagcgca tcccccatgt acttctcgtt tcgaagaatc aatctgactc cttctcctcg
     4081 ccagagcttt cgcttccctc ccgttaggat gccatcagcc attagaccat tagcaatttc
     4141 ttgcaaggaa ctgccctcaa ggtattcgcg gaagatgcgt ttgatgactt ctgcttcctt
     4201 tggttcaatc accaagttac catcttcgtc cttagtgtac ccaagaaaat gattgtggtt
     4261 gatacgtagc tgtccctgct ggaaacgata ctgtacgccc atcttggtgt tttgacttag
     4321 tgactggctt tcttgctggg ccagacttgc cataatggtc aaaagtacct cacccttcgc
     4381 atccattgta ttgatgtttt ccttttcaaa aaacactgca atcttcagtt cttttaactg
     4441 tcgtatgtat tgcaagcaat caaccgtatt acgggcaaag cgtgaaattg attttgtgat
     4501 gatgtactca acttcgccgt tttgacacgc ctcaatcatc cggttaaaac cgtcacgctt
     4561 tttcgtccca gttcctgaaa tcccttcatc cgcaaatatt cctacaagct cccaatcggg
     4621 atttctttga atgtagtccg tatagtgttg aacctgtgct tcgtaagaac tcgcctgttc
     4681 ctccatttca gtagaaacac gacaataggc tgccactttc aactttggtt tctcttcggt
     4741 attctctgct gcccattgtc taggcttcat tggaataacc gtcacctgtt ttcctgccat
     4801 ttcacttaac ctccttgatt tttgaatatg catattgcgc ttgtttgaat gggtcagaat
     4861 acttttcggt aatcttgcca gatttaaaat gagtgggtat taccttcgta tctggcactt
     4921 tgatctcctt gcgtttttta aagaacttaa ttcttcgttc ttgctccaga tccgcttgga
     4981 agaaaatatc ctcatcaatg atttttggat atatctcatt tcctaagtaa acctcattca
     5041 tcaaaatacg tttcataaag ggatgcggct tgttaatgcc agagcgtttg ccagcttctt
     5101 gtaagccaac accctcaagg taaatattga agaactcacg tatttgttga gcttgctgtt
     5161 catccacgtt gatttctcca ttcttaatga catacccgta tggaattgta ttgttcattc
     5221 tggtaacctc tctttcaaaa gtagtccgca cttaagttca aatccgactt cttggcggtt
     5281 gtaaactgta atgctgtttg tgaacttctt gaataaatct tcatcccagt ccgtcaacat
     5341 ctctgccatc cgcgcgaatt tgtataaggc ttctagttca atttgctgag tgcttttgcc
     5401 gttgactgac tcaatgatga ggcgctgctt ttcttgtgcg acagccctct cttgttgaag
     5461 tttgctttgt tcttctaaag acaccttcgt tgataaaata ctggaagcag tcaaacttgc
     5521 cagaacctca agcttttctt gaatcttgtc gatttcatca gcaagcactt cgagcccttc
     5581 ctgattcgca cctgctttat tcaaagactt cataaaaggt tccagaacca acttgtgtcc
     5641 gaaaatcaac ttattcaaca tggtcaaata agcaaccttc aaatcttcat ccgtaattgg
     5701 taatgcatcg cagctatctt tatttttaag atgccccgta cacttccact gaaccttctt
     5761 cgtattacct ttccaataag tgtgaacccg cttgaatttg ctgccgcatt tatcacagat
     5821 gatgttgcct gaaaatgcgt atcgcttggt gtactttttc ccgtcaccag tattcccttt
     5881 ggcctcagct tttctccgaa tgagttcttg aactcggtcg taatcttctt tagatactat
     5941 gggttcgtga ttgtttttga tctggtacat tggcaattcg cccttgttta tgcgtcgttt
     6001 gtactggtca tcaacaaagg tttgttgcat cgtcaaagtc ccggtataaa cttcattttt
     6061 caaaatactt ctgactgatg ttgcttgcca atttgcccca cgtttagtga attgttttcc
     6121 atcgtttaac cgcttggcaa tcattccagt cgaaatgcca tctaatgccc actggaacat
     6181 ttgtttaaca acttttgctt cagctgcaac gatgtgaaaa tcatagcctt tccgcttgta
     6241 gccatacggc gggtaagctt tgaatttccc tttagacatc cggtttcgaa tcgcccactt
     6301 caagttttct gaatgggaat aggattcact ttctgccaag cttgataaaa ttgaaagcaa
     6361 caactcgctt tccatatcac cagtattaat gttttccttt tcaaaaaaga tggtgacacc
     6421 aatatcagtt agctgccgaa ccagattcaa gcagtcaact gtatttcttg aaaatctgga
     6481 aatagacttt gtcagaatca aatcaatctt tccaagctct gcatccttaa tcaatcgttt
     6541 taaaccatca cgttttacag tcttggttcc agaaatccct tcatcataat aaacaccgac
     6601 atagtcccat tgttcatggt tcttgatgtg attttcatag tgagtaatct gggtttgtaa
     6661 acttgccagc tgttcattac ttgatgttga tacacgagcg tatgctgcca cctttagttt
     6721 ggaagcttcc ggcaactctg gacgtgccaa tttatgtatc gttttcatca gctcaactcc
     6781 tttccattag gtgacatgtt agctctaaag tgccgttata tcaacgtttc agaccattat
     6841 ccttgataaa aaaggattga atgtttcccg gtttttattg tcgattttga cgtattcttc
     6901 caggttgatt ttaccggtaa caagtaagtt cagaaggatc tgctgtgaaa tgtaataggc
     6961 tgcttcatct gaatagttaa tttctgtttt cttgttagtc attgctttcg cctcctcaag
     7021 atacaggcga agaaaatcca tgaaagtaaa cccaatcaca aattttcctt tgcctttcat
     7081 ccatatgcga aagaaataac cgactcgaac ccacaaaacg aaaaaagcct gcaagaatga
     7141 aacgaatcac tcttgcaggc ttctaagttt gtttatatat agtaggaatt attctttgta
     7201 aattttgact ttttacttcc caaacatcaa ataagccttt acaagcttca tccaataaat
     7261 aacaatataa atatcaattg tgggaaggag aaagttatga gtagttttga tatggaaggg
     7321 ttagaaaaag aatatgaaca tttttgcaaa tctgcgacaa caaaggaact ggaggaattt
     7381 gatgaaagct tcaaacaaga atttgaaaag tgctttaaaa ccatagaggc tgaagaagct
     7441 ttataccagt ttttacaagc caatataaac gcgatgaata atcgtatgga atcaatagaa
     7501 tcgcctcttt tctgcatcaa ttacaaagag caggtatttc agttaagaaa tcatttaatc
     7561 ctaatgcaaa atgctgtaaa cacctacctt aaagaaaact agacgaaaaa aaggccccac
     7621 aataaaactt gtgaggctgt tttgaattat aaagacgtca aactacttat tgaaaatttt
     7681 gtagctcgtt ggaaccatcg tgaagttttc ttcagtaatt gggccatcat aaattttgat
     7741 tttgcaaact tttgacgcca catcaaggtc gtgaacaaag taaattttat atggtgtatc
     7801 tccaagggag gcagcaacct cattagtact catttcaaat ccgtcagaga agtttgtttt
     7861 tgaagctttc acttcaatat ggatttcatt acctgattgg tcaaacgcac aaatatcata
     7921 gccatgacca tctccttcag ttttagaaac atgttcagga agttttgttt tgttcttttc
     7981 tgcttcctga atgaggaaat caagtacgat ttcttcgcct agagcacccg ttttttgttt
     8041 tgccttgttg acacgctccc aatcagtatg gcgtccagtg aattttcgtt tctgagtccc
     8101 attcgtgcga tttggtccca cttcatcaac aagaacagta aatccttttg aactttcttg
     8161 ctcaatttct tcaacttcct cgtttgtaag atccagttca gacggcaacg attgtgtatc
     8221 atcgattggg ataagatgac gattttcaat caatgcaaca aaatcggcat aggtaatttc
     8281 attcattcca tactgatccc agaagtaggc ccatgaattc ggctttttac gcttcttttt
     8341 gctaggtgta ttccaatcga agttttcaat aaatgaatca ccttgtttaa ttgccggttc
     8401 gattgtaaat gcgtgtgtaa ttactgccgt aacatttcca gcttcatcag gttcagaaat
     8461 gctctcaacg tatccgcccc cgtaaatttc ccacttacgg tctttagtaa ttttccccgg
     8521 atgacgattc aaaacaaccg cgccggcttt caatttacca tattggcgca tgttccaacc
     8581 gtaactttta gcatcatcag cgtatttcaa ctgaccatca tcttctgttt tcccgtgatc
     8641 taaaatgaaa gcttgttggc tttctgttgg ttctggtaac aaatctttaa acgtaaccat
     8701 atcgatacct ctttctataa ttcaatcgga acaaatttat gttctggttg aattaataat
     8761 aacacgttcg atattttaag tcaacaatcc ggacataatt ttgttccgat taaatttatg
     8821 aaatcaaaat ataatcgtca gattccgtct taccagtatt cttaccgaca gcacaatatc
     8881 caatcgggca acgagcccat acccaaccat ccgcaatcgt catcttctct gacttcggaa
     8941 gcgtccaagt tgcgccttta ttgtatgaac caacaaccgc accacttaaa cttggcttgt
     9001 tgcgaacgtt gagaccactc acttgaacca caagagtttt cacgttggat gttgatgacc
     9061 cagatggata aacttgatta ccgttctggt cgaacacctt ataaccagaa tggctatctg
     9121 cagcccgctt cgcattgttc aagtccttat aggcaccaat ttgtgacttg gcgtcagccc
     9181 atgatttgcg aacacgatac agaccactag ctggcgtgct tggggttgat gaaccattat
     9241 taatcgcatt ggctttatcc gcaatctcct gcagtttacc aagcaactgt cccggacatg
     9301 atgtggccga aaaatgtgag tgagggaaga tattcttgtt caccaccaat ttccctagac
     9361 cataacgttt ggcaatatct gcacacaact ttgcacttgc atcaatagtt gcttgattga
     9421 taccccagtt cggtgatcca gtgctattgc agtgctcaat cccgatactt gagatattgg
     9481 cgttccaatt accagcgtgc caagctgtgt ttccttcgtc cacgtatgct cgaatttctc
     9541 cattttttcc aataccgtag tgtgctgacg cctcacgcgt tttccaaata tcaggaacaa
     9601 tatcatagtt ggtggttgcc atgtgatgaa tcactatctt atctactttg gcaccactac
     9661 gaccattcga gtaatggcta aatgactgaa atccatattt tgttgctaga ttactaattc
     9721 ccattttctg tttcctcctt cttttcgtgt aactgctgca agatttcacg caacttttcc
     9781 ggcactggca gtccaatcgc cacggcattc tccagcagtg aaattccttc gtttgagata
     9841 tagaagaaaa tgaccgcatc acgcagtaca tttccacctt tgatgacttc cacatcaagc
     9901 atatgagcca caccaaccaa aagaaaaatc atgattttct tagtgatgcc ctttgcccca
     9961 atcttgctgg atagtttctt ttcgttgatt gcacgaagca gaccagttac atagtccact
    10021 accacaaaag ttacaagcgt ataaatcaaa ccatcaattc ctcccacata ccatccaatc
    10081 actcctccac cacctgcgat ggcgagttga atccaattcc acacttcttt catttacaaa
    10141 tcctccaatt gttctaaaat taaatcgagc atttcagcat ctttccctga aatggtgact
    10201 tcactatttt caaatccagc aaccaataaa ggcagcttgt cttgaagttc atccacgttg
    10261 atgtgggttt cttcgttgag caagtctgcc ttttctttgt gatattcagt tgcggtttct
    10321 gggatgagtg aaaaggcacc gtcatgttgg accaaattgc cgtgctcatc tttctttccg
    10381 tatttttgaa gcaagtctac ctcgtcttga tagagttcat caaccttcac ctggatgagt
    10441 tttgcaagct tcgttcgcac tcggctaatc tttggtggta agtcaaaacc ttttaagaaa
    10501 ctcatcacgt ccaccaaatc ttcatttcta attttgagca ttatctatct tctcctttaa
    10561 atcaccaatc tggacacaaa gatcatccac gaccatcaca agcaaatcaa ccatatccgt
    10621 cccaactttc attggctttg gaatatctgc ctcgataggt tcagttacta tcacttcttc
    10681 tttttcttcg ttcatggcgg cctcctaact gtatgtggtc attgaattaa acgactgcgg
    10741 attgtaccaa ccactcgctg taccgttgct actgaaaccg gttggtaaag cgattgttcg
    10801 tcccgcaagt ttggcacaga tttcacggat gactccaaag tcaacccact tcccatcatc
    10861 tccgagcatc agattagaac cgttgaatgc aataccagcg ctgccggaac ttgagccaat
    10921 cttagtataa agggaactac taaatgtaat cccaccaaca gatatttgat gttgtgtccc
    10981 tatacgaagc attgatggta aataaatgtc gtcgtcaaag tggaacccct tctccatacc
    11041 agactgcaat gttctcgcat accaagaaag cttctgggtg tagacactcg cagaggagga
    11101 atctttatga gcccatgaca tatactctgt tccatactca agatcaaata ccaatccacg
    11161 ccaatcagag tgaccactga tgttatttgc accaattgtt ccgactgtcg ttccaccacg
    11221 tcgaatggtc attccctgcg agtttatttc agtcacaaga gtgcttcctg aataatatcc
    11281 aatcgtagtt cctgtgattc gaatggacga actcgcagtc aatgctgtta ggatattagc
    11341 agcaatctta tcagccgtaa tcgagttcgc gccaatacgg gctgccgaca aagttcctgt
    11401 ggtaatcttc gccgcatcaa tgcttgcaat ttttgcactt tgaattgtgg catctgcaat
    11461 ctttgcgttt gtgatggccg cattttggat catggcagaa ctaatcactg cactatcaat
    11521 ggttgtttga ccagtgatgt gcaccttgtt tccagcaatc aaaatacttt caggtgagat
    11581 attgatttga ttaatcacgt ctcctttacc aactcgtaaa ttgattaagt ctttctgcat
    11641 gagaattgct gaatataatg tgttggcatt ggtatagtct tgccttgtgg tcgtaggata
    11701 aatatttcct tcatattcat cgggtttgat gctcgtgttc actcggactc gcattttcaa
    11761 tgtgccactc gggactgtaa ttgctccgct cgaaccagta taagagattt gatgataact
    11821 tgaaccatcc gacgggttta gagtaaaagg tgtgttgctt gaattataaa tcccagcata
    11881 tgtgccagtc ttaactgaaa agaaagctag atacacgctg tcagtagtaa tccctgatat
    11941 ctgctcagcc gttaacgtcc aagaataagt ggcattgctg ctacttgtaa cggtcgaaat
    12001 ctgttcccaa gcaccacctg tataaagcaa gacaatatta tctgatgtat ccttgcgacc
    12061 attccacgaa attacactcg gagcgacttt gccttccaat ggcaatttgt aaatgaccag
    12121 ataatctcct gaatttgaat aggggtttgt tgtcacgcca cttgtaatac tcatcgattc
    12181 aacgttctta cttactagat aactcgcaat ggtcgcatta gtataagttc ccgccgttag
    12241 ggtttcacta aattgttttg ccgttgggac aaaatcaatg taaggtaaat ccatgccgta
    12301 gtaatgatag tagaaagcag cttgagttcc gtcacgcagt tgcccgatat acttatctcc
    12361 cactttgaca tcaaggaact cacttcggag ataattggtt gcggacactt ctgaaccgtc
    12421 agtggtactc aaacttcctt gttcccattg attgacttta aatggaacgc cgattgcttc
    12481 tttggtttct gaaacactta acagtaaggc atcagtggtc gctgtaagtt ttacgacgtt
    12541 acttatctcg gataaatcaa catagccatt tgtcacatcc gttttcaaca tatagcaact
    12601 gatggtttct ggtgcatcac tagttgttaa acgaatgcga ataaaagcgg cactgcttgg
    12661 aacagtaagc ggtgtggtgg tgtttccaaa ttgggtgtac gataaaaagg acttatcctc
    12721 tttgtaataa agcagataag ccgttgcgta agtagagtaa agtttcccac ccacaaatgt
    12781 ttgaagtaga tacttttcgc catttctaac tcttgtaaaa cctgagcgaa cgtatccacc
    12841 ataggtattt tcttttccat catttgtatt cagaccacca actgcccact gcaaatctgc
    12901 aatgctcata ccggctaaaa cattgaccgc tttatttgtt ttagaaagag atagctcaaa
    12961 tctatcagca ttttgggtga tggtgctttc tgcagttgta atacgccctg tcagattatc
    13021 aaccgtcgat tgacttgcct tactagcaat ctgcccagct tgcactgtca gagttgattc
    13081 agctgtgatt actcgtcctt caagagttga cataccactc gccactaatg aaatcttgct
    13141 agtattctgt tcaacggatg tagtaagcgt ttcaacactt gcacctacac tttcagctgc
    13201 attcaaagca ttcacagcat cgttaaatgc ttgattggcc ttttcagtgg cagtattggc
    13261 atccttttgt gcttgttcca cggcttgctt tacttcttct gccgtcatat ctgtcataag
    13321 tggataccac tgagtgacgc catcacggat ttcatacacc cacatttcaa acttgtcacc
    13381 attttctttg taccaaacgt caccgagttt cggattattt ggagttgtcg ggccatagaa
    13441 gttggtgttt ttaccatttg ccgaactcaa tgcgtaattg gcatcgtctt tggcttgctc
    13501 cgccttgttg tccacccggt tgatgtcctt cgccacatcc gtgaattttg gcgtgatgtt
    13561 tccgagtgtt actgagatat acgctttcag aaatggatcg tatttgtatg agaccattct
    13621 agctgtgatg ttcaatccat cttcggcatg aataactgaa acagtatcac ccaaattaat
    13681 cgtttcaagc tgtgcaaaat ctttatattc ttcagttcgc tcaagcgggg caaactccac
    13741 atcataggtg gcttttggca aatcgacctt gttagctgag tattctaacc cagccaatct
    13801 gcgaagttca tcataggcct cggcttgagt aaactcatcc tcttcatcac caactttgac
    13861 gttgtcgtac ttgatgactt tgattttagg ctggacgtat tggttgatgt ttggactgtc
    13921 cacgtatttt tcgggaagaa atagtccatc atacccttgt ggcataatgc gagtaacaat
    13981 tccagagtaa tcaacatcag ctttatatcc tgtcagattc ttcttgtctc ggatttgtac
    14041 gccgttgtta ctgccacgag tcgttaacat tgaaatcgtg aagttatcgc gtacaatttc
    14101 accaccataa ctgctttgaa aaccattctc taggtcacta tcaagcaaca cctctacagg
    14161 atttagtcgc accaagcgga cattattgac cgcactgatg tttgatgtac cggtaaaacg
    14221 gtgcatgaat tgagttgcac caagcagttg tgtcaaagct cccgacccgt tcttgttgac
    14281 gatataagta tcttcaataa agtttgtggc taggtcatag aaaatatgat gagctactat
    14341 gtgcaaaaaa ccaccaagtg catcatctcg ttcaacaatc ctgaaaagct ggtcggacag
    14401 ttctggtact ggtgctttca caatcatttc tggcaacaat tcctcactgt gtggagcatg
    14461 aattggataa tcgaattcaa aggaaaagag tccgttcaat tcctcactca ccacggggtt
    14521 cagaatgttg ccatcaagga cagcgagacc gttatgattg aaatttgatt ctgttttgtt
    14581 gtaaagcgta atcataagta tcgccacctc ggttctattt ctactttggt tatacctgta
    14641 ccaagagtca cagtattact gccgactcga aactcaggaa agtcacctgt catgtattga
    14701 ttggctgcca catccccgta aaagcattct ttcaaatccg aatctagtgt caggttgcca
    14761 ttcgtcagat ttaacacgat aggcttgcca tttatcgtga gtgtcctagt tccattgccg
    14821 tagaccttaa tcttcggcaa tgagtaaatg ttgccgggat tattgaccgt tcctgacgtg
    14881 gttcgattga tagtcgctac attggtctta taacgaaaag gcgaacaggt taactccatt
    14941 tcaaactccc acatggaaga taaaatctga gttagtccgc tcgccttagc atacttgatt
    15001 gggtaaaaca cgtttggttc atttgaaaat gcgatagttt tagcgtttag gatttgtggc
    15061 aaaattatct gccagctagt ccaaacatca gatttccaaa tcactacctt aaaaccgaaa
    15121 gtcacatctt tccagccttt cagaatggtc aaatctcctt cacgtccatc aatctcaata
    15181 ctatcaatga cacgttccgt cactggaata actggcactt ccgtaattcg caaacctaaa
    15241 tcagtccgtg aattaattgt tccgtctaaa ataaatgcgt tcaattgacc accgcccatc
    15301 taaataacta aaaaaggacc agacaacaat gtctaatcct aaagtttata atctatcatc
    15361 ctattcggtt gtttcttcca gccctatttt cttggtaatc gctaaatacg cgtatacaac
    15421 cagcacgccg gaaattccat atattgcatc gattagatct ggtgtattca gaaaagtcat
    15481 catcgtttca catacaatat ttgcaacaat cagaccagct cccatcgcag taagaaccct
    15541 taaattcgtt cccataagca accaaagata gcctatcacc aaatagaaaa gaaagcttaa
    15601 tgcgaagttt gaaatgtgag aattaatctg attgttgatg aatacaaaac catgatttat
    15661 gccgctatac catcttactg ccgttaaaaa taatccaata gcaagcagta gaatatatcc
    15721 tatcagtgca ggtttctttg ctttaaattt atgcttcaac atatgattac caccatctct
    15781 tcagtaaaca ctcgttagtt atagtataca gtcaaaatgt gaaaatccaa cactaatatg
    15841 ctacacgtct acgattcaac gtcgccaagc tcttatcaat ttctggagca agtttgccga
    15901 ccaatgttcc atcattcaag acgactttaa tgtccattgc tttaagtagc gttggcaaca
    15961 tttcactcgt gatgtttgtt aaggcatcaa ccttagcacc taaatcaagc atcgagaatg
    16021 tgctatcaac ggcagcgtgg atatcggtat caatatcaaa gcttggcata taaagttttg
    16081 ttggaatagc tttctgcatc gttttagaaa caccagtcat ttccttatca aaacctacgc
    16141 caatcccttg tgccatgtac ttcccgattt catcacgaaa cagtgttgat ggtgaatgaa
    16201 taccaaagaa gtccttgatg ttgtctacta caccgccaaa gaatcctgaa atcttgttgc
    16261 gtaaccaact tccagcatca gcgataccat tccacaatcc tgtaatcaag ttcttcccga
    16321 tagttcccat agttgaaaca tactcaccga aagcattcgc aagccctgtg atgatttgcg
    16381 gtactgcttt gacaatggca gaaatgattg ctggtaagtt ttgaactaat gccacaagca
    16441 acttcacacc agcattgatg attttgtcga tgttgtttac caaagttcct gttattccgt
    16501 tgataatttg cggcatggca ttcgcaatcg ttgtgataat ttgcggtaac gcaccaatca
    16561 atgccacaag taactgaata cctgcgtcaa tcaactgagg gattgcccca atcacggcat
    16621 tgatgatatt ttgaataatc actggaatag ctgcaacaat cgcattgatg atatccggca
    16681 aagctgtcac aagtgatgtc aaaagttgaa taccagtctg aatgatttgt ggaatagcac
    16741 tgataataaa gttcacgatt cctgtaataa tctgtggcag actttcaatc agtattggaa
    16801 gtgctgtgat aagtccttgg gcaagtccca tgataagttg taaagcagca tccaacagta
    16861 atggcaagtt ttcaatcaag ccgttcacaa tcgttatgat tgcctgtact gtaattggaa
    16921 taagttctgg cagcgcttcg cctagtcctt ggataagtgt tgtcacaagt tgaaaggcag
    16981 cgtcaatcag taaaggtaag ttctcaataa gtgtttgaac aatcgttaaa acggcttgaa
    17041 ccaccactgg aataagtgtg ggaagtaagc caagtatcgt ttcaagcact tgtgagaata
    17101 atgaggttac tgcttctaag agtgttggca ataactgccc caatgcttga ataatggcat
    17161 ccaccactgc cggtaaagcc gacacgatat tttgaatgac cggtagaata ttcttgatga
    17221 cgttttgaaa ttgttccacc acattgccaa tcaacatacc aatgtcagcg ctgctgttac
    17281 caagtccagc catcaagttt gagattgcag acttcatacc gtcaatcgaa ccacttatcg
    17341 tctcactcgc ttccttggcg gttgtaccag tgatgcccat ttcggtttga ataacgtgaa
    17401 tcgcttcagt cacatcagcg aagttcgaga tatcatattt gacaccagaa atcttctcag
    17461 cctcttggag caaacgttcc atttcggact tcgtgccccc aaaacctaat ttcaagttgt
    17521 ccagcatccc gtaattttgc ttggcgaaac cttgataggc gttctggatg gactcaatat
    17581 ccgtccccat cttgtttgca ttatcgctca tatcagtaac agcttgatcc gcaactcctg
    17641 cggctttctt ggtatcacca ccgagagatg aaatcaaggc agctgagaaa cctgtgacag
    17701 tttccatgta ttcattggct gacattccgg cagttttgaa agcattgtcg gcattctttt
    17761 gaacggtgga tgacgcatcc ttgaaaagag tatccacccc accgactaat tgttcatagt
    17821 ccgcgtaagc agataccact tgttttccta gctccacggc agcagcgcca gcagcaagtg
    17881 ccactgtacc cattgctacc ccgatacctt ttagaacgcc accgaacttt tcaaatttac
    17941 ttccagactt ttcagcctcg tcacctgtat ccttgagttc gttgccaagc tcatcagttt
    18001 tcttagcagc atcaacttct tcagtaccca tggcgtcaat tgccttctcg ttgttagcaa
    18061 cttcacgctc catattattg agttgggctt ttgcattgtt taattgcact gtccaattct
    18121 gagtacgctt atcgttttca ccaaaactgt cactagcgtt cttcaaagca ttttcaaggg
    18181 tggtgatttt ttctttctgg gcatcaatcg atttgtttaa gacttggttg cgagcagaca
    18241 gtgagctgat gcttttatcg tttttatcaa attcggatga taccagtttc atttctgaac
    18301 ctagcacctt gaatgattgg ttgatttcac gcaacgagtt cttaaactcc ttttcacctt
    18361 caacgccaat ctttaaacca aaattatctg ccaaataaat caccaccttc ccttaaattc
    18421 cactcggtat cacatcatca atgaataact caactttcgg cttgctaatc ccagtaaatt
    18481 gcttatgaca ctcccataaa tccaaaaaca gtccaagcga gcagtaccag aaatcatctg
    18541 acgtcatacc catttgaact gtcccatagt aatacaggcg agtaaatgtt tcttcatcac
    18601 ttactcgcct gctttgtttt ttgaatctgt ttcactttcg atattgcgag ctgtgccctt
    18661 gaacattgct tcagtgattg ctgatttata ttcagccaac tgcaacggac tcgtcatcaa
    18721 ctccacatat tcagtcgtga gttcatcttt cttttctgtg ttcttcaagt tgtaaatctt
    18781 gatggactga ttcgccaaca gcgtaatcaa ccagatgatt tcatcaagcg ccaattcaaa
    18841 gttctcggat ttcaacaatt tctcaccaag gttatcaagc ccaccgtagt gactggcgat
    18901 ttctttcgtg gcttttgttg tcaaaatcag ttcatattca tctccgccaa ggctaatctt
    18961 ggcactgcgt tcttcactca ttgttgcctc ctagtctgct gtgaaatctg gttcataaac
    19021 actcgtgtac catccattga tagttgtttg ttcaactccc gtatcgtttt catcaacttc
    19081 tgctttccat ggatgcttac cactagcatc taacttgtta cgacgcatga ctgtaccctc
    19141 aattgttggt gttgagaatg taatgtcgtc accttttgtt gctaggcttg tgctgggcac
    19201 ggcaaacttc actcggtaca accacaaata tttgtatttg ccattcgatt tacgagcacg
    19261 gaaaccaatc gcaactggtg tgccaccatc ttcggttgtc gaaattaaga caccgttttg
    19321 atccacggtt gcaccaacaa gcactgccgc cacagcacgt ccaatatcat caacaccgag
    19381 cgttaacttt ccatttttaa attctttcac tacttctgat gcaccatcat cggcgtataa
    19441 agttgcttca gcaagttcca ccgaaagctc agctgagatt gctttcgcaa gcatagcggg
    19501 tgtgccgtat gtttcttcgc cagtagttgc cgactctgta atcggtgcat aatataattt
    19561 atccaatcca atcgttgcca ttttcagacc tccatttcat aatgcttggc gacatcaatc
    19621 gccacatgat agtaatttgt atctttttca aatcctacaa ataatcgttc agtaatcgta
    19681 aactcgtgtt tcaacaagtt ctgaaccagt tgtttttgcg tgttcagata gttgcctttc
    19741 acaaacaagg aaatgcgaac ttcctgtaca tcaacggttg gaaagttatc cccgtaaaca
    19801 tcgaacctgt cagcgagtgg tgtcagcaca caatacttgt ctggcgcttt atcactaaac
    19861 tcgcccgttt caacaggaat atgaagtgtg gcaaaaagac tgttcaattc ctctaaaatg
    19921 ttcaaatgcc gtttacctca ctttccattt ttgatttcat tgtttcaatg catgacttgc
    19981 gactttgtga ttttgcaggt ttcaagaatg gctttgctgg ctgaccgtgt tttccatatt
    20041 cgagaatgtt cgcaatctta gcatttgaac tgccatcgat tcgaggctca tcaaaaccaa
    20101 ccttgatgtt ccagttgccg cttttatctt gacgagcttg tgtgatacca agggctgatt
    20161 caagttcacc agttgaacga cttggtactt ttgtatttga gccaacaacg gcagttaagt
    20221 tacttcggac tttgccttcc accacttcag caccactttc taaaaccttg gggatgattt
    20281 catctgtctt gttttctagt tttgaaacct ttaacaagaa atcttctggc atcttcatca
    20341 atgctttagc catccgcact cacctccatt tcagtagtca gcatttcaag gtacatattg
    20401 cgatttcgga cattctccac cgacacaatc tgataccttt tctgatctga aatgacaacc
    20461 atctctgtcg taacctctag attaggaata taacgaatcc gaaacaggca ggtcgctgaa
    20521 ctaaaagtcg ccatgtttac ccatttctca gtcgcattct tttcctcttt gtatgcatgg
    20581 acagctgcaa gaacttcatc ttgtttcact gaaaatccag cgctatcctt ttggttcgtc
    20641 actttaacga tttgtattcg ttgattcatc tttccaaaac tcatacttgc caccgcctat
    20701 cgagcctgag taacagattg accgtttccc agacttgctt actggcattg acgttatccg
    20761 caaagaagcc accagttgaa ccatcacggc tttcgtaaaa gttactggct aacacaataa
    20821 ccgcctgttc agtggttggc ggcatttcat gttctgaata gtagccagac tcaatatgtt
    20881 gatagctctc agcataagaa agagcggtca gaatcaatcg ttccaacagc tcatcatctt
    20941 cgttatgctc aagtatgagg tttgccttga ccttatttag taagtcactc ataggctact
    21001 ccttaagatg aggcagatgc tttcatcttc aagatttgca ctgcttcagg taacacaagt
    21061 ttaccgtcca cacgttcttt agctaagaaa ccaaccatgc cattacctgc aaagagttca
    21121 cgcaactggt cgaatgaacg cacgccacgg tcgccaatgt tatagtagct gaaatcacca
    21181 aaagcaatga ctggcgcacc tgccttaacg gttggaacaa actccgaagt ataaactgga
    21241 taaccgagca gacggtcagg ttcacctgct accaaagctg gctgccacat gtaggcacca
    21301 ttgttgtctt tcaacttacg aagcaagctg atggtttggt cgttcatgat aaacttcgcg
    21361 tttttacgat atggacgttt caaagcatac acaaggttca ccacatcatc tgccgtaact
    21421 gcactttgag tattagttgt aatggcaact tgtccgccac ctgttgctgc aaaaataccg
    21481 agtggtttac caacaccgtc accattcaag aacgcatctt cttccgcgtt tgctaaggct
    21541 ttggtgaatt ggtcgatgat atagttttca aggttaaagg cgttgtcata aagcaattca
    21601 tcagtcacct tgattgccac atgaagtttg tgagcatcaa gcaagatttg atcgaacgtt
    21661 gcatccccaa agctcaactc gccaccttct tcaatccatg aagcggctgg tttagaacct
    21721 gcaatattaa tcttgtgttc accacttgtc gtaattgttg tcgcaagtgt acgcatgatg
    21781 ttttcagaag tcatgccgtc aatcaaacgt gagtcatatt cttctggcac caaataaccg
    21841 cctgccgtat ccacaccttc ttgaagaaca tttgaaacat gtcggaagtt tgagcgcaag
    21901 gcttcaagta caccttcttt atattcagct gaagcacgtc ctgttttctt aggttccatt
    21961 ttattttcag tagtcatagg ttgcgaagtt aatggttggc tcattggctt ttcaagttca
    22021 cgatccatcg cttccattga ctgcatacgt tcaatttcca tcgtaaagtt cttcactttt
    22081 gtttccattt ccgcataagt cttggcatct tcttcagaca tcaagccatc tttatcttgc
    22141 tttgcttcta caaaagcctt tgctccgttc caagcttgtg cacgtttttc catcaattct
    22201 tgaattttgt tcatgggtta gttcctccaa tttttcatta aattaagccg actcattaac
    22261 gaatcggctg ggatagtgtt attaatttct tctcgttcct ttggttcagg tggttcaata
    22321 cgacacttct tagcaatcgc tgaagtcagt gaattagtta ctttgacttc cgagtacatc
    22381 gaattattaa ccggaatatc cgggtcaatc tcaccgatga tttcatcggc aaatcctagg
    22441 tgaacagctt tatttgcgtc catccacgtc tccgcatcca tcatatgtgc cagttgcaca
    22501 cgcgataaat tcgttttacg ttcataggcg ttgataatac ttgctttcac ttcatcaagc
    22561 atggcaatgg ctttctccat atcaactttt tcgccaaacg caaccgctga cggattgtga
    22621 atcatcacca tcgccacagg actcatgagt accttgtcac ctgccattgc aataacactt
    22681 gcggccgaag cggcgatgcc gtcaatcttg actgtgactt tacctttgta gtcagcaagc
    22741 atgttgtaaa tacttgcggc agcgacacaa tcgccaccac ccgaattaat ccagactgta
    22801 acgttacctc cacctgaatt taactcatct ttgaaaatct gcggtgtgac ttcatcatca
    22861 aaccagctct cctcagcgat tggtccgttg aggtagaggg ttctctctag gatttcctct
    22921 tggttgtctt gattcagaac cgtttgattc ttccacttcc aaaacttctt catcttgttc
    22981 ctcgctttct tctttgttta cgccataagc tgccccggct tgttcaattg gcagcatatt
    23041 gccattgaag taatatttcg caccagcacc accagggatt gggttcaagt cctcaagttc
    23101 acgcacatca tcaggagata ggaacccatt ttgaataccg gttgcatagc cttgttgacg
    23161 tgtggcatag tcaccacgca ataagccatc cacattaaac tttatgaaat acttttcttt
    23221 ttcatcgcga cttaacagtg atttattaag tgcttgttcc caacgattga gccatggtga
    23281 taatgagaac ttcacaaaat ccaaactcaa atgttcaacg tttgagaagg tcgcgtggtc
    23341 taagtcgcca accatgtgaa ggggcactcg gaatatccgt gcgatttctt ccagttgaaa
    23401 cttacgtgtt tcaaggaact gggcttgttc tggtgacatg gaaataggcg tatacttcat
    23461 gccttcttca agtactgcaa ccttggccgc atttgaactg ccaccaaatg tcgcattcca
    23521 actttcacga agctttcctg ggtctttcaa agttccagga tgttctagga caccaccagg
    23581 attggcacca ttggcaaaaa atttagaacc atattcctct gttgcaatcg caagcccgat
    23641 agcattctta gccatggcaa ttggtgaata accaaccaag ccatcaaagc caaggccagg
    23701 aatgtgaagc acgtcagctt ttgaaagtct gacttgcccg acatcagctt gatataaata
    23761 atagatttcc ttgttgtcat cgcgattaac cgtcatctta tctggcatta aaggatacaa
    23821 agctacaact tcacctttgc catttcggat aatttgcgca taggcgttac cccaaagtag
    23881 caggtgagtc attaaggttt cacgaaatac aaatgatgtc atttccgaat ttggttcatc
    23941 atgcagcaag aaatacaacg aatgtttcat tgctttatct ttgccgccag catctcggta
    24001 ttggtaaaag tgtaatggca atcctgccac ggcttctgat agcacgcgca cacatgagta
    24061 cacagccgtc atctgcatag ctgtttgttc ggtcacgctt ttaccagctg atgagccgcc
    24121 aaacataaat cggtatggat tcatgatggt ttgatttgtt ggtttatcgc gtgatttgaa
    24181 tagtgatttt attatgccca ttgattgctc ctttcaaaat ttgagtatca aaaaagcacc
    24241 tacgatttgt agatgctgtg ttcacattag atataaaacc gacttcctct tgacaaaatt
    24301 atctcaattg cattatttaa aaaggtattt acttcctcta aacatttcga tttttcgtca
    24361 ggtgttaagg attttctttg ataaggaaag aatgaactac ttggtgcaag ttttttaaac
    24421 gtcatataat cttcatcatc gaagaaatct tgtaaataat ttagttctat aaaacttttc
    24481 caatctttga atttagagaa atagtcttta ttattaacga taaatttatc agcgttagtt
    24541 gatgaaccat atcgtttatc tcttacatca gaataaaata aatcaggaaa gtcatgatac
    24601 ggccctttac ctttaacacc attgagagaa ggttttgata catatagtgg cataaaattt
    24661 gcaagagtat gacttaaatc atagaatttt acaaatttca ctttcatctc ttcggtgata
    24721 tcatcggaat ataaaatgac tttcaaacgc ccataatgac tatctggcat tgaaaagttc
    24781 ttttgattat agcatttcaa taaccgtatc gttgcaccag caattgtgtt gaaagaaata
    24841 atcgtttctc ccctataatt cccaattcct tcagcatact ttgtcaaatc ttcagttaga
    24901 atttttcccc accattttct ataaaacagt ctagaaatta atgtgttgtc cgggtctgaa
    24961 gatattttat ctggtgctac ttgaatcaaa tattcattca tacacataca cctccaaaga
    25021 caattatatc aatggattgt aataaaagct catatttcac agaaacaaca atcccctatc
    25081 atcataaaca ctggcaccat tatcatttcc acaacgaatt gcacgatcca gagccataat
    25141 tgtcgcgatg gcaccatcaa tcttctcagt ggatttttct ttatcagctt tgatattacc
    25201 tgccgggtca gttcggacga aaatgttgtc catattccaa cgaagaaccg gatgaccgcc
    25261 atgggctaat ttctgttcaa gagtcaactt catcaactct ttagtagccg ggctcatatc
    25321 cttgaaacct tgaccgaaag gaactacagt aaatcccata ccttctaagt tttgaaccat
    25381 ttgaactgct ccccaacggt caaaggcaat ctcccggata ttgtatttct cacccagttc
    25441 ctcaataaat ttttcaatga aaccatagtg gactacgttt ccctcagtgg tttgtatgta
    25501 cccctgcttg gcccacaaat cataattcac atggtcgcgt ttaactcgta agtccaaggt
    25561 atcttctggc acccagtaat atggcagtat cacaaacttg tcatcctcat cttcaggtgg
    25621 aaacaccaaa acgaaggatg taaggtcggt cgtgctggaa aggtcgagac ctccgtaaca
    25681 aactcgacct ctcaaacttt cttcatctgc attgaatgaa caagcgtccc atttatccat
    25741 tggcatccaa cgcactgctt gtttcaccca ttggttcagg cgaagctgtc tgaatgagtt
    25801 ttcttcagct ggattttgtt tagccgaatc acaagcagcc accacctttt cttctgcaat
    25861 cgttatccca agtgacggat tggctttctt ccaaacttct ggatcagtcc aatcatcatc
    25921 ttgcttgata ccgtaaatta acggatagaa tgttttatca tgctttcgac cttcaataat
    25981 gtcgagagct ttttgatgct gctcataaca aattgaattg gtatcattcc ctgccgttgt
    26041 aatcaaaaag aatagcggtt gcgttctagc atcccctgcc cctttcgtca tgacatcaaa
    26101 cagctttctg ttaggttgtg cgtgaagctc atcaaataca accgcagaac tgtttaatcc
    26161 gtgtttagag tatgcttcag ctgataatac ttgatagaaa ctattcgttg gctgataaat
    26221 aattcgtttt tgtgaagtca ggattttcac tcgtttgctt aacgctgggt tctggcgaat
    26281 catatcaaca gctacgtcaa atacgattga agcctgcgct cgatcagcag cacagccata
    26341 tacctcagcg cgttcttccc catcaccgca agtcaaaagc aaagccacgg cagccgctaa
    26401 ctcactctta ccattcttct taggtatttc aacataagcc gtattgaatt gtctgtagcc
    26461 atttgcctta atcgttccga ataagtcacg gataatcttt tcttgccaag gcatcagttt
    26521 gaacggtttc ccgaaccact gacctttcgt gtgtttcaac aactcaataa aggccacggc
    26581 ataatctgca cgtgacttat cataatggga gtctttgtcc ataaattcag ttggtttgta
    26641 attatcgatt ggaactcact cccttctacg caaaaagcag ctgttgtcag ctgccttaat
    26701 ctctttattc catcatatcg gcaatgaact gaatggcttc agggttgttc ttgttatccc
    26761 gcagcaattg caccagttct tgccaatcgt agtatccttc ttcaatgcca tcttcattat
    26821 ctggcatgta aatttgataa tccatcattt atcaccctcc aagataaagc ggctgtactc
    26881 atctttgtgt tcttcaatga aaatcaccaa ctcgtaaaag tgccggtcat gtgcaattcg
    26941 ctgcactgca atcgcatcaa acatatttgt cagaccactt tctgcaatct caatgatttg
    27001 ttgcttaatc tttgcgttca ttttgaccgt cctttctgcc tgcctcatag gccgcaatta
    27061 aggcatcttc caaacaccaa accgcaatgt ccaagaagtc ttcacggtcg ctgttgtggg
    27121 ccttcaggtc gccacgttca ggcaactgaa cgatgtaatt ctttgcgatg ttgtaaatct
    27181 tacgtttact cactttcatc ttaaagcccc tttctgatgt agatggtatc ttctgttttt
    27241 gactcaaggt caacccagac caaatcgtgg ttcaatatca tgtccgtcac gtattgccaa
    27301 gcatcattga aggtttcaaa tccttctctt ctaccgtttt gaaagaccaa ttcgaagtct
    27361 ggtttgatga tgtgcaccac atcttcgccg tataccgcgt tcagtgttga accgttgtcc
    27421 cattggataa ggattgaacc aatgtcgtca acaccggtta ctgtgccttg tgtgcccttc
    27481 gctggggcat gtgggtcgtt catcttgatg agttctacac gactaccttc agggtaacgt
    27541 tttttcatac cctcgatttg ttcatgagtt ggaaacataa ctttgtcttc cgtattcttt
    27601 tggtagtcta tatatcactc taaagggatt ttatagcaag tgatacgtta tttattcagg
    27661 attttctagg tcattaaatg cgatagtctt tccatctcga atcactgaaa cgtctgcatc
    27721 gcttccagcc tgctcgatat aacgcttaac aatcacatca cagaactttt catccagttc
    27781 gatcgtatgg caaatccggt cggtctgttc gcaagcaatc aaagttgatc cgctgccacc
    27841 aaaactatcc aacacgatgc agttgctgag tgacgaattg gtaatcggat atgccaacag
    27901 cggaattggt ttcatcgttg ggtggtcacc attcttcttt ggtttatcaa attcccagat
    27961 ggtcgattcc ttacgtccgg tgtaccattg atgtttgcct ttcttcttcc agccatagag
    28021 caccggctca tgctgccatt ggtaaggcga acgaccaagc actagactct gtttcttcca
    28081 gatgcacgta cctgataaat agaaccctgc atccacgaat gcttttctga agttcaagcc
    28141 ttccgtatcc gcatggaaaa cataaatact ggcgtcgttg gccatcacac tttccataca
    28201 agaaaaggca tcatacaaga agttgtaaaa tgcctcgtcc ttcagattat catttttaat
    28261 cgttcccgct ttaccttgat atgagacccc ataaggtgga tctgtcacca caagatttgc
    28321 tagtttgccg tccatgagtt tctcataagt ttcaggtttt gttgagtcac cacaaactaa
    28381 acggtgacga ccaagcaacc acaagtcccc tgttttactg aaggctggct tttcaagttc
    28441 ctcatctaca tcaaagtcat catcttgggc atcatcatta ccgttgagta atttatcaag
    28501 ttcatcagtt tcaaaaccaa gcaaatccaa atcaaactct tcaccttgca ggtctgataa
    28561 ctcaaccgcc aacatttcat catcccaacc ggcgttcatt gctagtcggt tatcagcaag
    28621 tatgtacgca cgcttttgtg cctcggttag gtgttccaca aacacgcacg gtacctgctt
    28681 gataccttct tctttagccg caagaatacg tccgtgacct gcaatcaagt tataatcctt
    28741 atcaacaatc accggattta tgaacccaaa ctcacgcata gaagcttgaa tctgtttcac
    28801 ttgatcctta ctgtgggtac gggcatttct ggcataaggg accagcttat caatatcaac
    28861 tttctcaaaa cgttctgttg tgttcattag aacaaccccc attctgctag tttctcaaac
    28921 ccgccaagct cattcacata atcacgcgca acttccacga tttcagaata aggcacgcca
    28981 tcaatctcag tgtcaccaat cgcacagctt aactcaacgg gcataccagt ttcttgagct
    29041 ttcaagaatg cgtagatgtt cactgacaca tcagcttttg ataagtcttt cccatggata
    29101 ccgccacctg ttactccgtc tgccatatcg gaaccaagct tgcgattagt cgcacctgta
    29161 tccacatccg ggccgccagt ccaatcacct agagggttga ctgtagcgtt tggatatttt
    29221 tgttttaact catttgtctt tgcgtggctc tgacaaatta tcaagcgttc accatcaaga
    29281 atgtactttc catcaaatgg atggtcctga tataagtcac gcgcaatttt tgagagctgt
    29341 aactgttcat cagtcaatgg catcccacga aagattccat tatcgccaca acgaatttca
    29401 gtcgcttgat tgtcagccaa ctctttatct tggggcacaa tcaccacatc ttttttaatt
    29461 ttgcctgcga tacgattaat cgcttggctg atttcattca aatttaaagc agttgaagtt
    29521 tcaataatca catgacagat gccatgacca attaaaacct caactgctat ctttggatta
    29581 ttttcttctg cgtatgccaa gtccacaatg gctccggcaa tacgatctgc aactttatct
    29641 ggatgttgcg gattaacctt ctctatcata aattctgttc ctttcaacca ttcttagaac
    29701 gtaacaatcg ttccatcgca tccgtattcg gatctcctgt gtattccact gatgcattct
    29761 cttttacaat ctgttgaatc tcataccacg tcacatttgc ttgcttttgg aagttctgcg
    29821 acatcgccac aaatggggag gccatgactg ccttggtagt cgggtgtttt ccgagcaaac
    29881 catattgact cagagcattt tcacattgaa caaaacgcgc aaagttctga gcgtaggact
    29941 caaccattcg tggggctatc aacgtttcgc atccgcggtc tttcaaccat tggaacgttg
    30001 agttataaat ttcatcagcg cctagcacag tgccatcctt ctgttttgca gaaaggtaag
    30061 cacttggttc aggataatca ttgccctcaa gctctacacc ctcaccaata tcttcaccaa
    30121 ttaataattc aacatccggt aagtcaaatt ccatccgcga tgctttcttt ccagcagcaa
    30181 ctttatcaac gagtggctgt gagcgttccc ctgaacgagg tcgtctgcca ccgcgttgtg
    30241 ttccatcttt tgccaaaatt tatcacctct ttttcttgtt tggggctatc ccccgtttga
    30301 actgaacttt tttcgcgtaa gggcctagcg cgctgtacag tttagaaggg tttagggata
    30361 attaccgccc ctccccccct tgttattttt cacatgattg ttttatcttt tgtgtttcgt
    30421 cgagtcatgt gaattttcga gtgacatgat ttgcagacac tcatcaaatt attttcatca
    30481 tgcgtaccac catcacttaa ttccttgatg tgatgcacaa tctcaaccga agtaaagcgt
    30541 ccttccttca gacacatctc acatagggga tgtgctgcca cgtaccttgc ccgtattttc
    30601 ttccacgctc tgccgtaacg tttgttgatt gccggatcac gctcgtattt ctcgtaacgt
    30661 ttcctcgcaa gtgttttatg ttcatcacaa taagtatcat gcgtacggtt cggacaacct
    30721 gggaacttac aggggttagc tggtttcatt ggcaagtggg gtcacatcct ttcgggcaaa
    30781 agaaaagccc ttgaaggatt tttcccacaa aggcttcgag tatttgttcg atacttctat
    30841 tgctggtatt gcttgagtat cgtttgtctt ttttgacatc ttaatgatat cactaaaggc
    30901 tactgacatt cactgacaca tttcaaatga ctatgggttc atctggtagc ttcaagttct
    30961 caagagcttt gctatgccaa cgaaagactg tccgcacgtc agcgtgaaga tcttcagcaa
    31021 tcttgtccca gctctcttcc aacaggtatc gattgattaa cacaatcttt tcgtccacgt
    31081 ttgtgagttc atcaatcacg ccacgcattt gtcgtttgag gtctacaaac ttatcaatct
    31141 ctgcatcaat ttcagcttcc aattggtaac acttctcaag gttacgaaca aatggtgcct
    31201 cagtattccg tgtgccactt gaaatctttt cttcgaatgt tgtggaagaa actgtcaccg
    31261 ccagttgata gagctccgcc ttctctttaa tccggtcgtc aattcgttta ttcaaacggt
    31321 acgcttgttt caagtattct tttggtgtca cttgcttccc tccaatctag ctttcactgc
    31381 atcaatcaaa catgattgtg ttttatcttt tcgtttcaaa gccaacatca catcttcatc
    31441 aatcgtatct ttcgcaataa tgtgatgaat gaccacagta tcactttgcc cttgtcgcca
    31501 cagccttgca ttggtttgtt ggtaaagttc caaactccac gtaagaccaa accatacaag
    31561 tgttgaacca ccagcttgta aattcaatcc atgtcctgca ctagccggat gaatgacagc
    31621 gatggggatg ctaccttcgt tccaatcaat aatgtcctga gacgttttga tctgtcgaac
    31681 gttgaatcgt tccttgatac gctccagatc atgctggaac caataggcaa tcagaatcgg
    31741 tttgccattt gtaccttcaa tcaaatcttc caaagcatct aacttctggt catggatgtg
    31801 atgactcaca ttaaactcat catagattgc tccattcgcc atttgtagca gtttattcga
    31861 aagcaccgct gtattggctg catcaatggt ggcttctttc aattgtagca ccaagtctgc
    31921 cttaatttca tcgtactttt gcttttcttt gagtcccata tcaactggca cttcattcat
    31981 cacaagctct ggcatatcca agaaatcgac tgacttcatt gaaatcgtga tatctgaaat
    32041 cttgtcgtag atttcttgtt ctgcatcttc ccttggtttc caagaataaa tctgcatgcc
    32101 attttgcttg tcaggtagaa agtatttatc tcgataacgt gaaatataat agcccaatct
    32161 ctcgcccata tccagaacct tgaactccgc aaacaaatcc atcaaaccat tacttgaagg
    32221 tgttccggtc aatccaacaa ttcggtcaac cttgtgtctg actttcataa agctagtgaa
    32281 ccgtttagct tttaagtttt tgaaggacga cagttcgtca atcaccacca tatcaaaatc
    32341 aaacgtaaaa cccgatttgt taatcagcca gtccaagttc tcacgattga tcagatagat
    32401 gttggcatta ttttgtaatg ctgccattcg ctgacttggt gttccaagaa ccacggaata
    32461 cgataaatct ttcaaatgat cccacttttg aatttcagtt ggccatgttg attgcgtcac
    32521 gcgcaacggt gcaataatta agacacgttg tattgtaaag tcatcatgca tcaagtcttt
    32581 aatagctgtc agcgttgtca ccgttttacc caagcccatg tccaatagaa gggcggcagt
    32641 tttatgatct ttgataaaat caatcgcata tttctggtag ttatgtggta cgaacttcat
    32701 cagacatcac ctcctattct ttctagtaac tcaggtatct gatcaatctc atcaagcacg
    32761 aaacactgaa accctaaatc tgtcagttgt ttcatacgaa aaagctgtaa agaccgtggc
    32821 ttcttccctg gcgccttcac ttcgacaaat ccaagtttcc catttggcat aagtaccaat
    32881 cggtcaggca caccagcaag ccccggtgat gtaaacttcg ggcaaatacc acctaccctt
    32941 ttgacggctt tcactagtgc ttgctcaacc tgcttttctc tcatagccac accgtcaaat
    33001 actcgaaata cgcatcacgc aagatttcca agtattcctt ttctgcgcag tgaatcatca
    33061 gatgtgcgac ttgcttatcg aatgatttct tccaaggata cgtgacatcc gacatggcaa
    33121 actcgtaaaa ctcatcaaat cgtaaatcac gtttaccgat tccaatttgt aaccactgtt
    33181 taaatttcat ttagatattc tccaatctgc aagtatggtg taacccgtga atacgcaata
    33241 cataacttta tataggtggt aattttttat cccttaagaa aagttctata taagacctac
    33301 acaggttaca ctttccttta aaatcaacta ttccaagaac tcggatttga gttgcaaacc
    33361 aacaatcttg tttcctttat tagttcgccg gcgcttaaat ccgcccgcct ccagagccgt
    33421 gtaaaaatcg gctgaactac gaatgtactc accagttcgc gtacaaaacg cacgatactc
    33481 tgcatacaac tcaccagatt tttcttcaaa gtcaacagca gtctcgcagc actcgtctaa
    33541 gaaatggcca agccaatcat tcgccgtctt atattcagaa attgcattag cgacaacttg
    33601 tggaaccgtt aaatgaaagt ctgcggcgat gacttttttc gcaccgtcaa ggatccattg
    33661 caaaatggct ccgccggcat tttcaaaaag gtagtccgca taattcttga tgtccttatt
    33721 gccgtcaatc gtagcaagga atggaatcac aattaaacga cgccaggttc ctttatcaat
    33781 cgctccaact tttgggaggt ggttggtata gagcaccaaa gtatgcgttg ggacatactt
    33841 gaatgggtct ttgtatttct tctcagccgc aatttcatcc gtcgagcaga gctgcttaat
    33901 gttagatgtg ttgagtcgca tcccctcttc aagctcggct gcgatgagta ggcgtttccc
    33961 cttcgcttcc gcaagttcag gtttcacatt gcgtcggatt tgacttgtaa gaatatcagc
    34021 tgagatgctg ccagagtaat taccgagcac acggctgatg acattccaga acgtggactt
    34081 cccgttacgc ccttcaccat acgagatgat aagcgcttca acgtaaactt taccaatagc
    34141 tgcaagtcct acaatcatct ggacataatc aatcaactct tggtcaccta cgaaaatggt
    34201 gttcagagcg tccaaccaaa tctgctgatt ggcgtcactc ggggcacatt ccgtttgctt
    34261 cgtgatgtaa tcttctgagt tgtggtcttg tgatttgcct gttcgcaaat caaaggttgc
    34321 tgttggtgtg ttcagcaaga actcgttcac atctagtaac cgttgctcga tttcaagcat
    34381 gggctttgcc tcggttaatg ctgacgagag atacttgctg tcgcggcgtt tgacagcaaa
    34441 cttcttatac tcttgtgcgt gttggtacaa atcaaaacta tgacgttgcg ctgtgttgaa
    34501 catggtgact gcctttttcg gaccaacact agcaagtaca tcgaacgcgc cattactaac
    34561 catttccttg gtacgcttct caatttcggt ttcagattct tccagttgac gttctgtcaa
    34621 tgcgtggatc acaccttgcg cttttggttt cgactcttcc caatagctgc cgttgtagac
    34681 aaggtaacca gttgacggtg agtaatgaag cttacattca tactcgcgag ctaagaccgt
    34741 tgcttgacct aagtccgagt agtcggttgg ctcaagtgat aaatcagagt tgtactgctc
    34801 tggaggaatg tagccttctt gttgtttcac tttcttccca aagttgaccg cgctattcca
    34861 gatagcttta agctcctcct ccggcagtgg cggattacat ttttgggatt gttcgagata
    34921 cttgtgatac gtatcttccg ttgcaccgta gcgtttgatg agctttcctg cgatgtgact
    34981 catgcttgaa ttacggctgc cttcgctaat ctctgactgc gcattatccc aatcagcaaa
    35041 cagatcatct tcgagaaaat cagtgatcaa cttactacct tcatagattt caacttcaga
    35101 gtttggtgtt ccgaaaagca aacgtgccgc atccatcgca ttgttgtcaa agtatgggaa
    35161 ctcactttga atctgcttct tgagttccac atattcatct ttatcagttg tggcaggaat
    35221 cgggaaatat acgtgaaaac gtggacgtgc tgatttgcca cctttgtctt tcatgttgtt
    35281 acgtgaatag ctgaccgcaa acgtcacatc aggaaactgc atcgccactt cgaaaggggc
    35341 tacccaatca tctggattgt ctgagtggtc attgtcgcaa tcaagtggaa tcacatcaga
    35401 ctggatgaag ttgtcacctt tgcgatagtt gcctttgtac tcagccatca catgatccag
    35461 cttgaccgtg gcaacaagtg tttctttatc tgtcaccact tgcttggttg ggaacaatcc
    35521 attcttggaa ttacccacct gattggatgt gaataacgtc atcttaagca tttgagacct
    35581 ccttcatctc atcatcgaag tacctgatat gtttcttcca atactccgct tgttcaattt
    35641 caactgccat gccttgggag atggtgtcac ccaccaccca gacttcctca catttgccca
    35701 tgagaacaag tgacatgtgc attgccacat cacgctccgt tgcgtcgtcc atgaattgtg
    35761 gatacatcag atgtgccgca actggcatgt agccacggtc aagagcaata cggcagtaac
    35821 gcttagtgtt tttatggttg acgacaacat ttcctgagaa cggcgagcag acatagactg
    35881 atgttctgta atctttacgt ctaggcatta ttatcacctc gctcaatcac tggtaagatg
    35941 ttcttcttcg atttcagcaa gtcgtacaag aacaaacgac ctttctgcgt ccagtaggta
    36001 tgcatcacgc tgcgctctgc atctatcgca tgagtttttg attgtgtgta gccttgattg
    36061 gcatacttct gataaagcaa ccacatcttg ccttgcttgt actgaattcc cagttcatga
    36121 agcaacttgt tcattgcctg tggtgacata ccgtagtcct tcgagatttt agaaatcgac
    36181 atcacagaat tgttttgaag aatcaaatcg tagtagctaa cttttggttt catctccaaa
    36241 atcatttgtt gttgcatcgc caccatttct tttttctctt gtagctgctt caacactgaa
    36301 atggcccatg ctggatcttc gattgacttt gtgatgaaat cttctgtcgc gtacacaccg
    36361 tgttggcgga tagacggcaa gacctcattt gtcacccaac gcttgaattt cttcgcgttc
    36421 ggcatcttgc tagaaatgat gagtgagtac aatccacttt cgttgataag gatagccatt
    36481 gtcccattaa cgctgaacga ttcgttcacc gtcttatctt cctcatcaac atgatctcgt
    36541 aatgcttttt gtggatttgt gtagccaaga attgatgcta catctttacc aacaaagtga
    36601 gggacatcgc caatcatcac cgtgcgtaca gagccaaact ccgcattttc aaaaactttc
    36661 aattcgttca tcttgtgaac ctcctgtaat agaattttca ggagaggcat tttgcccctt
    36721 ctaacttaca ggcgaagaaa atggtcgaaa gtaaactctg actcgaattt atttttgatt
    36781 tttttgcctt cgtctataag cgaagaaaga acccaattcg aaccttattt ttgataaaaa
    36841 aatttgaaaa aaatatggag ccatttctga ctccacattg actaatcctt ttgatagaat
    36901 tcacactcgt atccatcagc gttcagtagc aagccttcag cccacttagg cgtttgactc
    36961 atcaactgac agatgtcttc aaccttcgat tccattggca cttcgataat cacttcgtcg
    37021 tggacgtgcc cgacaatgcg atacttacga agattctcca ttgcgaaaca gagaatgtct
    37081 ctagctattg cctgcacgat gttttcgaca aacttgggac catagctttc aagacgttcc
    37141 catttcttgg tagcaccgac accttcatag gtaacagctt caccgccgaa tttgttctca
    37201 ccaatctttg gttttacata aactaattta cgtcctgaca agagttggat gaacagaaaa
    37261 cccgacttgt attcaaactt gatgccatgc gtcgatgtgc tccgtcgttc tttcacacaa
    37321 gtctttactg ccttatcaac agcccaccaa agctccgtta tgttaatgtt tgagtctcgc
    37381 caagaattaa caagcggctg taattcatcc tcagttagtc ccatttcaag agcatccatt
    37441 gctttcaatg cacccaccga tcctccgtac cctagagcaa gctcagcaat tttccctttt
    37501 tgacgtagat gcccattcac gccatgcttt tcaactggca caccgaacat ctgactggca
    37561 gacgcacagt aaatatcgcc accatttttg aatacttctt gacgccactt ctcacccgac
    37621 agccaagcaa tcacacgtgc ttcaatcgct gagaagtcag atacgataaa tttcatccct
    37681 tcacgtggta caaacgctgt ccggaggagt tctgagagta cgttcgggac attgccgtag
    37741 agaatgttaa gcatttcaaa attgctttgt tttactaaac tacgcgcttc agataaatct
    37801 gacatatggt tctgaggcaa gttttgaagc tggatgccac gtcctgcaaa gcgtccggta
    37861 cggttggctc catagaattg gaataaacca cgagaacgat tatcagaaca cgcaaagttt
    37921 tgcatggctt gatacttttt cacggatgac ttggcgagtt gctgacgtaa gaccaggact
    37981 tgctttaaat tttcatcaat aggttgttcg agtagttcgg ccactgcctt tttaccgagt
    38041 gactcggttt caagtccgtg gtctagtaac catccccgca tttgaagcac gctgtttgga
    38101 ttttctagtc cagttaattc ttgcaattgt tgattcaatc cagcttttga taattcatcc
    38161 aactgaacgg cagcttccac aaagtcctta tcaatctcaa ttcctcggtc gttgatttcc
    38221 tgatccagcc agtattcttt ccaaacagaa tcaagcactg gaaaattgga aagttttcct
    38281 tggatagcta tttcaacttc cacatcacga ctattgtatg tcttaaatgc tgaccattta
    38341 gttggcgcat ggtgtggtaa gttcctcgtg cgtccaccat taactttggt cggattgcat
    38401 ggcacgcaaa agtatcggat gaggtctttt ccttctgtga gcttttgttt atccaaacca
    38461 agaacagcac caactcctac aagtgacaac ggcaaaccta atgtcgcacc ccacaccatt
    38521 gtgcattgcc accctcgtgg attcaaaaag ccatccaacc ccagaaagcg tgacaaacac
    38581 acacgttcaa aactcgcatt gaaggcgtgt ttaatcactg tttcatctga tagcgaagtt
    38641 aatatttcag ccgggatagt ttcgtccatc ttcagatcaa ccacttcgac gggaccacca
    38701 tctacactgt atgcaaatag cagtatttca aaatcggggg actctgaata tttgtagaca
    38761 ccacatttcg ataaatcgac actactatac gtttccaaat ccaatgacaa atgtttcatt
    38821 ttcttcctcc aatcaaacag gcgacagcac ttctgccatg gccgtttttg ttttaatgat
    38881 taagccaaga aatcatcatc cgccaaggtt tcaaactcat cgcttgcaga tacttgtgag
    38941 ccgagtggtt cgccgtcacg tacaaactgg atattcccaa gccctgccgc taccccgcga
    39001 tttccatttg cgttaaaggc atagaaatta atcgacacac gagcgtagca accactatac
    39061 acttgtgaac gatccaagat tggttgaacg tgctgatcca cgatttgtgg tgcagtggtt
    39121 gagttcgcat taatgaagta atggccttgg tatgcttcat cgtcgcgttc gatatcccca
    39181 tcacgtaatg gcagcttgat ttctgctttg tttggtttct tcccaccgaa tttcgcaagt
    39241 ccctcttcga ttgctgcatc gattgctttt tcaatggtat caatcgttct cttatctgat
    39301 tttggaatca agactgctgt tgaatatttc tctgcgcccc cgttgatgga tgctggttcc
    39361 caaccgtgga agtatgagag acgtgtgttt gtaccagtga ttactttgct tgttttagac
    39421 atattattgt tcctccgtta atggtttaaa ttcttcgttt aagttgttta ctgtgaccgc
    39481 ttgtcgttta tctgaaccat cgactagcgt cagcttgcct tttggtttga tgatgtattc
    39541 gcccaagatt tcattgaatt tctctttacc gagtgccttc gtcattgctg tgacaccaag
    39601 taacttttta tcatatgggt cgtatccagc cttgatgacc gccgcagcga catcattgtc
    39661 attagaatac ttacgagtag agcgaccctc gactaatttg tgatgagtcc attgtttgcc
    39721 accgagtgca agtttcaaag cacagtcctt gatatcgtta ctccaagaaa ccaggtcatc
    39781 cactttaccg atgatttctt cgatttcatc atcactaaga agctctggtg gtttgaactc
    39841 atattgcgcc agtttcaagt tatggtctgc tcgtgcacga cagctattct tcgccggaca
    39901 gaatccacac catttcccgc attggtactc accctcacct ttgaaagcta aatctgcggc
    39961 aggcgacaac acatcttttg cccactgaag taattcttct ttcagcagtg tgtacgtact
    40021 cacattctca cgccttggct ggaaaatggt catcttgact tcttgaatgt cataaataac
    40081 atcgaaaagc tccaacgctc ccaaggcata acacatcatc tgtgggttct gatacgcatc
    40141 taccaaaatt cctagaccgt atttcatgtc aataacagat agggttccat ccgcaatgac
    40201 gagacagtcg ccggtcccaa agccgtctgg gacgtacctt gagaagtcga gccgctgttc
    40261 tactattaca atagagtcaa ctgttgtctg tttcgcctta gcgacttctt ccatgacgaa
    40321 ggtcgcataa ctttcagcac actgctccat ctcctcgtcg tagaattcaa gcgtagatgt
    40381 tgggtctgtg acgtcattac caatgaactt attcagtttg tactcacata aggtatgagc
    40441 atcagtgcct tgttgggcat acgggctcga cttgttttca aagtgctctg acaagcgaac
    40501 acttggcgga cagtgaatcc accgattact tgaagatgcg gataggactg cgtgttgtgt
    40561 tggcatctac aatccctccg catctgcaac caaagccgcg tagttttctg tcggcacatc
    40621 actcaagcga ctggcaccat atttctcaat cagtgctttc acttcagttg acttaccttc
    40681 ttgagattta cgtgccaaca aaccacggac ttcttcaagc gtcggttgtt tgacttctga
    40741 ttttgtttcc attgtcggtt ctggtgtttc aacttgtggt tcaggttcat tggttttcat
    40801 cgccacagcc aactcttgta agctatcagc taacgcttgg acgtcctcaa cgacctgaag
    40861 aaatagtttt gttttactca cgtcattacg ctcccttctt gttaacttca cggatttcga
    40921 ctgattcgat tgtgtcccct ggtgtgagca cgagaatttt gtccatgttg cccttaccga
    40981 acagccaccg tgcaaaccag cgaggcaaat gacgcacacc accttgtagg acagtttctt
    41041 tgttacccgt gtcatcagtc acgtttactc ggattttgtg ttttaggttc atgatggtcc
    41101 tccttcatct ttatttgttt aggatctact cccttacaca atacaggcga aggaaaacgg
    41161 ggaaagtaaa ctcccccgta acttttttct aaaataattc tttgatcttg tctttgatga
    41221 ttccaaaggt gcgattgatt gactgttttt tcttgtcaag cttgtccgcc acttcagtct
    41281 gagacatgtt ttcagtgacg agcatgtgat agatttcttg gtggtacggt aataattgcg
    41341 tcacgacttc acgcaaacga tcgatacgag gatcttcttc attatcttgg taagcatcgt
    41401 aaaccaatga ttggatgggg ttgtccccct catcgcattc atcatcaaat tcattgagcg
    41461 acaaattgta gttacgtttg aagtaatcgt tggcttcacc atccacgtat tcgtccattg
    41521 gataatagcc gtgctcatta ttaaagtctt cacggaactt ctctttccaa gccttgatct
    41581 tttctttttc ttcttctgtg cgttcaggac gtgcgttttt ataaaagttg taaatcgcac
    41641 ggtcgtcagc gcgatgcagc tcctgaatgt taagctcagt gacgccgtct tcgcctgggc
    41701 gaatctcaac cacttctttt tggatacgtc cattggcatc agtacgctca aacacgtact
    41761 tgtaagtgct gcggtcgttt tggtgtgttt tcataaatct actcattaga tccctctttc
    41821 ttgcctgaaa gagcttttga gcaaggaaaa caaacaggga ccgtgccaat acgtacaccg
    41881 tccctcatca cgaaaaaaga gcgcaataaa gtaaggcata caatatctga aaaattttct
    41941 ggataaccag ttcttttcag tatttgtaac cttgccctat tgcaactcag gcattgttat
    42001 attttattag taggactatt cgcttttaag ataaattcgt tcactttctt gaaacataat
    42061 gtagtgttta tgaaccataa atgataaaat taaatagtta aactactatg ttttaattat
    42121 agaaaaaggc ctcccttgtt ttcgtcagtc atcggcggca aacggcggtc aacggcggac
    42181 gtaacaaagg aggttgtatt ttggaaataa gtgaaattac tcaaacgctt tatccgttta
    42241 tgggaagcga gtacgtgaag ccacaggatt ttttaattgc tttactggat agtgtttcaa
    42301 atgatgacga ggccaccatt ttcggttttt ctgatgataa cctacgaaga ttttacaatg
    42361 gtactcgacc attaacacaa gagtatgcag ttcgggttgc tggaaaattc aacatcgaca
    42421 aatgcacgac ttttatttat gaacgtctta tagatgatgc tccaaccgtc cttaagcaac
    42481 aattgattga taaaggtgtg gtaatcccca aagatacaga cgtttctgaa atagtggccc
    42541 atcttttact tgatgaaatc acctcaattg cttctcaaac aaaagtaaaa acaaaaaagg
    42601 ccaagccgaa gcttagcgaa ttagagctcg caagtttaag aatcaacact aatggtgatt
    42661 tctcttataa tgatgaagtg aaaaaattct ttgacgattt gccagttccc cttgatatta
    42721 gagctgagga gatgacgtat gtcatagctc ttttttcagc atatgcagat gccgatggat
    42781 acgaagtata cgagcataca aacgacctgc caaattcgcg gctaaaggat ttcaagagac
    42841 agcgaagaaa ttactataaa gctgaaagca tacgtcgtgg ggtccgtgat aactttacac
    42901 aagaggaagg aactgagcac tttgaagctt taaaagaaga tatgtacgac ggcatcgagg
    42961 aagtctatga agaagactac gatgatggcg ttgagagact caaagccgtt ctacagcagt
    43021 cgtctgttat aacattaaac ggatcaatct tatcgtttat accgggattg ctgcaaaatt
    43081 ctgctaaaaa aggcatttgc cacatgctgg ttaatgacgg aaagatcaaa tgggtgactg
    43141 aagatgaata gtttgtttaa tactccattt gaaatttcgg ttcgagtaat gttactgctc
    43201 tctgaattta aagagcctgt cagcgctgat agaattttaa tcacagactt catcaccacg
    43261 tatggtcgcg actttgaaat ttccgattac aacttaaatg gtgataacag ctatagattc
    43321 agtgaattta ttgcgcgacg tgaattagtt aaagatgcag tcaaaaatct tgtactgcaa
    43381 catgttatcc aaccatcgca aagcaaagaa ggttttaagt atgctttatc agaagatggc
    43441 ctaaagttga tatcacaatt cgtatcggta tatgcagaaa aatacttaca aatagctgac
    43501 gaatctgtta aatacattca agataaaagt gacgttgagc ttctgcgaca aataaaccaa
    43561 cgcgcaaagg aatttaaagg agagcaatga taatgcaaaa ttattatatt gaacgtgtta
    43621 ccataaaagg caaagatcgt gaagatgcaa ctgtcaagtt caccaatgga ctaaacataa
    43681 tttctggccc ttcaaatacc ggaaaaacta gcattgttac ggcaatcgat tttctctatg
    43741 gcgcgaaaaa agacgctgct cccttttcaa ccgatgcaac cggatacagt aaagttgaac
    43801 tgattattca atcgactaat ggcaaatatt cattaactag agaatttgat agcaactcca
    43861 ttttggtatc caaaataacg agttcaggtg aatatgtaga ttatgaaaaa tataatgcac
    43921 gatctgggaa aaatccaatt agccattttt ggttacaact tttaggcatc gatgatgatt
    43981 atcagattat caagaatgag gatttcaaac gtcaaaaatt aacttggcgg acattagcgc
    44041 ctagcacact tattccacaa gatagagtca ataccagcgc ctctgttctt tttcctgggg
    44101 aaacaaccca acgcacagct tttttatcat cgttgttact tctgctatac ggttcagatt
    44161 ttgcgaactc ggaagaaaac gaaacaaaag aacataaaaa aattagaagg aactcggtga
    44221 ttaactacat caattcaagc ctttctgaat tatatgaaaa ctacgaagtg gctaaatcag
    44281 aattacctga ggctccctct gatgattttc aacaaattgt cgatggaatg ttcgctgaac
    44341 ttgaaacaat tgaaaagcaa atcaatgatg cgttagccag cagcaaaatc ttgataaaag
    44401 agatttatca aaaggaacag tatcttcatg aaactcaact tcttttgaat aggtacaaac
    44461 agttacatta tcaatatcaa tcggatattg aacgactaac actaatcgta gatggtgagc
    44521 gattattaaa tgatcataat gaacatgata cttcacatag ctgtccattc tgtaacggcg
    44581 aactaagtaa acctgtccaa acaacctaca tcgatactgc taggtcagaa ttacattcat
    44641 tgctctctca attatcagat ttgacggaag aatctcatga taccgaagtt gaactgcaag
    44701 agttaatgga acagcttgat gagcttaaaa caagaaagaa atcgcttgat gcagcaatca
    44761 acgatgaact aaaaccgaaa gctgagacgt taaaggatcg aatcaataaa atcgaaactt
    44821 acagggatat taaacaacag ctaatctcga tggaaaaaat gcaaaataag cttaaaagtg
    44881 atcttgaaaa aatcgagaat gagccagaag acgaacgtat cctttataaa cctaaagaga
    44941 aatttgatgc agaattctac aaagaaatgt ctgagttact ggactccatg ttacgtaata
    45001 tgcattataa acctaatgaa tttcgtaacg catttttcgc caaggatatt ttcgacatca
    45061 aaatcaatgg aaatctaaaa tggaccgaaa acggacatgg atatacagcg tttatcaatt
    45121 cagtagtggt aatggcatat cgacatctct tgtataatca cgctaagtac acaccttctg
    45181 tgttcattat cgattcccct cttcttggat tagatgaacg caaaaaacaa gatggcgatg
    45241 acaatatgaa agaaggactt ttcaaatact ttatggatca tcaaaacgaa ggacaactta
    45301 tcatcgttga gaatacaacg aacttgccag cactaaacta tgatgataaa caagtaaatc
    45361 agattgtctt tactgaagat aaaaacaatg gacgctatgg atatctatac gatatttata
    45421 actagaacag gaatgattac atgaagttta gctacaatcc gctttggaaa ctcctaatcg
    45481 acagaggact gaataaagca caactcagaa aaatgactga tatcagttca gcaacactct
    45541 caaaactaaa taaaggcgaa aatgtaacaa cagatatctt acttcgcatc tgtgaagcac
    45601 ttgattgtga tttatcggat attgttgaaa tcgttcgcga ttaaatatca aaaatgcact
    45661 gtattcgatt catgagtaca gtgcattttc atatttattt ttgtaatcca gcgattactt
    45721 cattgatttt cgattcaata tcattcaatg gaaccatata ccattcagta gcttttttga
    45781 agtttccatc ctgaaagaca acttgtttgt cctggaatac atgatggaga gtgcgctcaa
    45841 gtagctgagc gttgacattt tgtacttcag cagaaagcat gaccttcact ggtgcattta
    45901 agtaggtcac gtcgttttcc gcattggcaa ttctactttc aacatcattt cgagtgaaac
    45961 caatcttata caggttattc cacttgctaa tatccggatt cgtgcttaat gacttcagca
    46021 cgtagatata acctgtcgta aactcttctc caaagctttc agccagtgtt tcctcatcta
    46081 ccggctctgt caccatcctt ccatgacgtt cagtcgagta tagagacgaa gctaaagatt
    46141 gtaacaacag attcttattc tctgtcccat tctcataaac aacatgcatt ctggcatttg
    46201 ttttcccatt atcagcgata aaggtatcct tcgaaatgga aacgatatac atcattacgc
    46261 cgttttggat gtagaatcta ttttcatgaa tatcatactg ctcaaacggg ataatttttc
    46321 gtctgccaga tgcgatatct gcatgcactt gatcgaacaa gctcttatac ttttcaaaat
    46381 gacttgcatg ttttctgcgg ccaattttat ctgcagcgtt cacagttcta cgatagcggg
    46441 aaacatccaa caagtctgaa aaatcatcaa tcatatcatc tgagcctaag atatcatcta
    46501 aattcaactc gtcatcgatt tcaactgaat cagcgagaaa ctctccatcc ggttcgaatt
    46561 ctttctccaa taaaccaaga gtgtcatact tcttaacctt ctcagacctt tcgggttttc
    46621 ctcgaaatcc gctaagacga gcccacaatg cgcgttcact agaccattca ggagtttttt
    46681 ctggctctcg tccgttttca ttcacaaagt ctataatctc ctgaaattta gcaacttctg
    46741 ggtcttgttt tacaactttc tttttttcaa cttgcttggt taaatcatca aaagcgtcat
    46801 cttcaaagat gctatctaaa ctattcgcca tcttctttcg ctgcctctct ttcacgtttt
    46861 atctcagcaa gtcgtagcaa agcaaaggcc aagtattttt caccatcatc tttactattt
    46921 cgatcaggat ttcgaccatt ttctgcacgg aacttcttag cagcttggta ggccgcaacc
    46981 aattgttcgt cagtaaaatc atacttattt gatgacaaat aatcctgaat aaaccgaaga
    47041 gtcggtgcat caatatcacg actaatcact tcatacgcac gttggaacgg attcacttga
    47101 tcgattaaat caatattcaa ttcatcaatg ttaatgaaac gatcggccat cttaataatt
    47161 tcgcggctac catcttctga agttgttgtc cgtccagccg caatatttat atcggcaact
    47221 gtatgttgac gaacggtttc taactcttcg ttcgtcaaat caggataacg atcaatgatg
    47281 acacgtggaa tcaacgtctt attaatcatc ttcgcatcag cacctgaaac aatcgcattt
    47341 tgaatatctt ggctctgtaa aatgctagat ttcaaatctt ccatatcatt ttcgatgatt
    47401 ttctttgtac gttccgtcgt atcagcaggt ttcagtcctc tgattgaaag atcacctggt
    47461 ttgtctggct taccatcttt tggtttaaac ttgtaaactg gcgccaacac ttgttccata
    47521 agtagagatg cagaaattgc cttcataata ctgttaaccg cgaataatac ttcgtcatcc
    47581 tgtgcatctg gctgcgcaat aagatttgta aactgtgcat gagtcttatt ggggctgtca
    47641 cgagttacgc gaccaatgat ttgaatcact tcagttaatg agttacgata accgattgtc
    47701 agtgcatatt ccgcaaatgg ccaatcgaag ccttcttttg ccattccaag tgcaatgatg
    47761 atatcaagct tatcaagatc tttaatgtca tccgtaatac ttgctagata tgctgagact
    47821 ttttcacgtc cttcttcatt cacaaggtcg gccactaata gttttttacc atctggacgt
    47881 tcgatttcat aaataccatc ctcgttctgt gtgatattac caccgtccgt caataaatca
    47941 agtatttcat caacttccgc gtatttatct ttagtagact caccagaatt aacattagga
    48001 atatggataa ttgatttttt gttgacatca attactttat ccaaagcatc tgtatatttt
    48061 ccacgataga aactataccc cattgcaaag gatttcagat atttatatcc ttccagttgc
    48121 tcataataag tgtaagtgac cttatcaaat ttatcttcgt cggctggttc cagaatctga
    48181 acagagtcgc cacggaaata tgaaccagtc attgctaaga tatgcgcatt agagtttgac
    48241 atgatgctac gtaaggcatt acctaacaca gatttatcat cacggctcac atgatggaac
    48301 tcatcaatcg ctaatagcgt attgtcaaat aatgaatcgt ccaactcttc aaaagcaaat
    48361 cgcaacgtag catgtgtggc aatcaggata ttatcacttg ggtcagtcga gttcatgaat
    48421 ttaacaaagt gttgaacctt tgatttttca ccgcccccaa tagttaagtt gtcacttggc
    48481 tttacttccc aatcccaata aaaaccaaac ttcgataatt cagtatcttt aaatgattta
    48541 ccaattgagc gttcaggaac tgcaataacc acttttttaa ttccttgatt atggagttta
    48601 tccaagccaa caaacatcaa tgcacgtgat tttcctgaag ctggtggtga ttttaccaac
    48661 aaatactgtg acgcacgctt ttcataaaca cgttcttgca tttcacgcat accgaggtca
    48721 tttgttgttt ttgattgatt tttatcaaaa ttaatttcaa ataaattact agtcattgat
    48781 tgtcatctcc tgatagagtt ttagtaatgt tccaagtcga tcttcgtcag attcaaacgg
    48841 gcgttgctga taagctctat caacaatccc atccagttcc tggtgtttct tacgtaatga
    48901 ttctggcata ctgtctttat tatacaaatc ggctaacgtg ccgccttcgt attctcgtaa
    48961 atcaagaatt tctgtcatca cgcgagtcat ttcattttta cgctgggcgg ataaatcctg
    49021 aatcggaaaa gtattataga ctaacccggc tgaataacgg taccgagttt ctaatttccc
    49081 accgacagag cgcagccaca ccatatgcat tcgggattct aacagaccaa gcagccacat
    49141 tggagcgtta tagattgcca tagccgaatc tgaaattata gtatcgctcc caactatacc
    49201 cataggaaca taatctcttt tttctgatga cacacgagga attagaatac tattctcact
    49261 ggtttcatca taacgaactt caccaaatga ccatggcttc tcagctagtg ctcgagtttc
    49321 ttttctcttg cttttttccc tataactttt tacatttttt attgtttctt taataagaga
    49381 attttgtttg tatctagttg catcttcctc ggtcaaccat aaagtatatc ttaagtctcc
    49441 atttattaat cctgttgatc ctaaatattt cttaaataaa tgtttaatat ctggatattt
    49501 ttgaatcaaa ttccagtatt ctgccactga aaaaactaga ttaccaccat catttgccat
    49561 actgccaaat ttcaaagagg gtaaatttga aatactattt cttgattcgt tgacaaatac
    49621 attttcacca ttagctaaat atgcattaat atttgaaaca ctcattactg acccattctc
    49681 taaatataac ttaggatgaa tattcacatt atttgtcata ccaataatga caacagtcac
    49741 accggcatta ttctttgcat tgttgttcca cttaaagctc tgatatgcaa atgaaattct
    49801 tacctcatct tttaaaaggt acggccaaag gatactaact tgttcacctt gacaaattga
    49861 attagtagta acaaatgcga acgagccatg agatgttgca atatattgtt tagctttcca
    49921 aaaccaccca aaaatataat caagcaattt atattttcga atatcgccaa caagtttttc
    49981 catatcttca cgttgttcag cattttgaag acttttgccc agatacggtg gatttcccat
    50041 tatatatatt tcatgatttt ctttgagtcg caacacctca ttccaatcaa ttcgaagaga
    50101 attggcacac actatattcc cagcatcttt taacggtaac aactcagcaa tggtacctgg
    50161 tattgcttct tcaagctctt tattcatttg atgttcagca atccataatg aaagtcttgc
    50221 tacttcatgc gcaaaatcat ccaattcaat cccattaaaa ttaccaagat gaatcactga
    50281 tagtggcatg gaatcattat tttgtaagtc gcccaacaat tgcaaaatct taatttcaag
    50341 tctacggatt tccttataag caatgatcag aaaattacca gaaccactgg cgggatccaa
    50401 aaacttaata ttagaaattc gcgtcaacaa agcacttaga tcattgatga ttgttctctt
    50461 attatcgttt cttgtttttt cagtaatgtc cttcagctcg ttttcttcac tgcgaagctt
    50521 taaagtttca aatgactctg tcaaatcatc taagaataac ggcttgatga ctttcatgat
    50581 attcggcacg cttgtataat gcataccggc aacgtgacgg tcttctgctg aagcaactga
    50641 ttgaatcatt gcgccaagga tatcaggatt gatttcattc caattcaata attcccctgc
    50701 ttcaataagc agctctcttg aaacttttga aaaggtcaaa tccacatgtg gctcaccaaa
    50761 cagttttcca ttaacatatg gaaattcaag tagccactca tccttgccat tgcgagctaa
    50821 ctcattaata tccaagattg caaagagttc tttgattact tcgttaaaat tcgaaccatc
    50881 ttcagccgtt cttgttttta gaacatttgt aaaggaaccc ttattcataa ttcctgtatc
    50941 ttctgcaaac aacaagaaca gcactcgaat caagaacaag ttaaatgcat gctcgttggc
    51001 atcaggatta tctttagcca ccacatcata caattttgca aaacgttcag cagcttttcg
    51061 gtcagctgga ttttcagctt gataatcagc cttctcaatg ccattccacg ctaagaaaaa
    51121 gtcagcatta gccggtagct cttcaattgg aatattcaaa gtttcatgag ttttcgtatc
    51181 aattgcagca atatctaaat aatcgtttac caagatatat cgtggtttag atttttgctc
    51241 tttgattgat tgagcaatcg catcaatcgc aatgacaacg ttgccttcaa tttcttcata
    51301 atgaagtttg ttcttaatca caaatggttc accattatcg aattttgatt ttgcacgtgt
    51361 aatcgacgtt ttggggatat cgtacaagga caaaaattga gtgatgaaat catcgcccct
    51421 atttgaaagt atttttttta caccatcttc aatttcagtg atgtttaaaa ctttattttt
    51481 tgccatttat ttaacatcct ccgcatctat aacatctgaa ctaattattt cactaacatc
    51541 aacatttaag gcagcagcaa ttttcaataa tgactccatt gcaaccaact catttttacc
    51601 gagttttgct attacattgg gactgacgcc agatatttca cgaagttgag ttttgttcat
    51661 attcaaatca atcaataact tccacaattt attataagaa attgacatac tacacctcta
    51721 ttctactggt atcttcaatt atatcatcta tgagctatca ttattatacg aaacatgaaa
    51781 tattttcgcg aacgcaaact atttttctaa aataaaagcc ttcagcatag atttactaaa
    51841 ggcgagataa caaatattaa ttccacttta ttttaaccgg aatccccaat tgacgagcta
    51901 gtttatcaat tttgattctg acattctttt tgttgaaatt tgcataaacc catactccat
    51961 cagctaccct ggctgaattt ggtcttccgt tatacatgga tggtttacgt cctaaaatta
    52021 tagcgaacga cggcgtctca tcgacaatta attcttgcag ttgattgttg tagtttccat
    52081 ccgcaaatag ctgagaaaca aaatcaacca ataaacctct agcagatttc gaagatatct
    52141 ttttcccatc atactcaatt tcatattgtc cagatgaact aaattcataa atttgggttt
    52201 cactgtcttc ggaagtacca aacaaatcga tatttgcaat ttcatctata atttcaaaca
    52261 ctgtgtcata tagctgatcc gattttgctt tttgaagttt atcaatatac gaagtattac
    52321 cagcagttga attcatcatt tcatagtcag atttttcttg gaaatcttgg ataagtcgtt
    52381 tttcaagata atctgtatct gcttttgaca ttttcccatc tgctcttgta aagaataaaa
    52441 ctgattcaac ccaagcttta tattccttga gaaagtgttg agataaacga agtgaaattg
    52501 attgccctgc tgcctgaccc acgtaacgct tattaccacc aatcaaaaca taaacagctg
    52561 gataatttga aaaatcctgt tccttcaaat acggcaaatc actacgactc attgaaacca
    52621 agattgctgg ctcgcgttca aaataagaaa tattatcttt ctgtgtatct gaaaatataa
    52681 aaatttgctt cataagtttg tctcccttga aaactcgata atatattata tcacgtaacc
    52741 gttatcaaaa tcatctaacc tatcaagtct acggtgtaac tcctatcaac tcaaagctcc
    52801 atagcatttc catcaactct acgctcaccc aaaaatcgtc atttcaacac gaaaaaagag
    52861 caatccggaa accatcccga atcgctctaa tccttgtcat atcaacgttc cacacgtgta
    52921 agcagtccta cacactcgat gtgatgggtt tgcgggaaaa gatctacagg ctgaactttc
    52981 ttcacggcat aacctgcttc tgcaaataac ttagcatctc ttgcaaaagt tgccggatta
    53041 catgagatat agacgattcg ttctggtgac atttcgattg ctgattcaat aaaatgatga
    53101 tctaatcctt ttcgtggagg gtcaactacg atcacagatg gtttgatccc tttttcttgc
    53161 cattttttca taactttttc tgcttttccg acttcataat gaacattttc gattttatta
    53221 tttaaagcat tgaactgtgc atcttcaatt gcttctggaa taacttccat cccatacacc
    53281 ttatccactc tgtctgctaa agacaagcca atcgtaccta ttcctgaata agcgtcgatc
    53341 acaatgtctt ttttatctaa ctcggcaaac tcgatggctg tttggtacag atactctgct
    53401 tgttgagtat ttacttgata aaatgacttt gctgagattc gataggtttt tcctaatagc
    53461 tgatcttcga tatagtctct gccatataaa actttttctt tgtctcctaa aatcacattt
    53521 gttttttctt cattgatatt ttggatgacc gaaaccactt ctggcaattc ttcatgaata
    53581 gcttcagcaa tttccttgga tttaaagaat ttttctttac gagtaactaa aacgaccatc
    53641 atttcatggg aataatgacc acgacggata atgatgtgac gaagctgtcc ttcatttttt
    53701 tcttcattat atcctcgtac ttggaaccgt tgcaagatat ctctgactac tttgattgct
    53761 tgatcgatga caggatcttg gatataaaaa tcttcgatag ggactagatc atggctattc
    53821 tttttgtaaa aaccggtggc taactgtcca tcgatacggc gaacagggat ctgtgcttta
    53881 ttacggtagc cgaatggttc tgccattccg accgttggaa gtacaggaac ttctggcatc
    53941 ttagcaatct tcgccattac atgctctact tgtttttgtt tgaagacaag ctgttgttca
    54001 tacttcaaat gggctaaagg tgcgatacct atgcgaagta atgcattgtt ttctacaggc
    54061 tgacgatcag gtgattgtgt aataaatgtt tcgacttttc catatccaaa cttattgcct
    54121 gcttttacta ctagtatttc tacttcttct ccagggagtg cattttcgat aaataatgga
    54181 taaccatcga tttttgctac ccccattcct tcataactca agtcgacgat ttcgactgta
    54241 tatcgttcgt ttttctttac tatttgctgt tctgtcatat tttgctcctt taagcctatt
    54301 tttcaatcct actgaactct actataaatc agctaattac acaactaaaa ccggcactga
    54361 ccttactacg ttcagcaccg gcttttgatt aattcttttg attaggtgtt tcgtctgcta
    54421 tttttccgtc accgtcgata tcttcatccg ttaaacgttc gacttctttt acgaattctt
    54481 tgctgacaac ctctaattct tcttcatctg tacctgtgat tgcttcatca ggaatctgat
    54541 cggtattggc aaagaactca atgtgttgat gaagattttg gaaatgcatc ggtgcttccc
    54601 cgccgtattc accatctaag ttgatcatta ctggtcgatt gatatcatct tctgtttcaa
    54661 cgaacaaact gcttgttttg gtatagatta ttcttggatc atcgacatgt cgaccgccat
    54721 tcagcatgag tgctgcaata tgcaagatct caaagatatt tgctgtcttc acaatgatta
    54781 aagaaaactt cccatcatcc aatttggcat ctggcgcgat ctgttcgaat cctccaacag
    54841 agttcgtcag ccctaggaaa aacatcgaag catttccgat atattcccct tcatcatact
    54901 tcaagcgcat tttgattggc tttactcgag ggagcatctc tgctcctttc gcaagataag
    54961 caagataacc aaaaatactc tttagttctg atggaacttc ataagtcaat tctgtcaaat
    55021 agccacctgc agcgatattg atgaagtaac tgttatcaga aaggccgatg tccattttta
    55081 cggtttggtg tttttttatc acttctgctg ctgctttaat attatctcta ggaattttta
    55141 atgctcgagc atagtcgttc gttgtaccag ctgggatgat ggccatttta ggacggtgtt
    55201 caagcggagc gattccatta accacttcgt tgattgtgcc atcgccacca gctgccacta
    55261 ctagatcaaa acctagttct gcgactctac atgcttcatt cttggctgaa tctggttctg
    55321 gtgtagttgc ataggcgctg gcttcaaatc ctgcttcttc taatgcctgt aggatatccg
    55381 ccaaattttt tttcaataat tcttttcccg aggtggggtt ataaattacg cgtgcttttt
    55441 tcattttcag cctctatcgt ttcgctaatt catctttaag tagcttattc acgacaccag
    55501 gatttgcttg tcctttagtt gctttcatga tttgaccgac taggaagcca accgcacgat
    55561 cttttccatt tttgaaatca tcgacagatt gttggttgtt atccaaaatt tcattaatga
    55621 ttggcagtag tttgttcgga tcagataatt gcacccaacc atttttttca actacttctt
    55681 gggcttctcc gccatttgtg atcaattcac ggaagacttt tttggcgatt tttgagctga
    55741 tcgttccatc ggcgatcaaa cgaatcattc ctgctaagtt ctcaggtgtc aattttgtct
    55801 cagctaattc cagtttctca ctgttcaagt aagcagaaac ttcacccatc aaccagttag
    55861 atgcttgctt ggcatctgca ccattttcca aaacagcttc aaaaaaatca gacatttctt
    55921 ttgtaagtgt caataccatt gcgtcatact ctggaagtcc aaactcacgg atatagcgtt
    55981 cgcgacgaga agctggcatc tcaggcaaac tagcttttac tttttgaatc cattcgtcat
    56041 cgatcacgaa tttcgggata tcaggctctg ggaagtaacg ataatcacta gacccttctt
    56101 tgacacgcat caaaactgtt ttattcgttg tttcgtcaaa acggcgtgtt tcttgttgga
    56161 tttctcctcc tgaaagaaga acttttgctt gacgtttttc ttcaaaagct aaaccttttt
    56221 tcacgaaaga taaagagttc aagtttttca attctgcttt cgtaccgaac tcttcttgtc
    56281 cataagggcg aagagaaata ttggcatcac agcgcataga gccttcttcc attttcacat
    56341 cgctgacttc tgtaaattgg ataattgatc gcaatgcttc tagataagcg tatgcttctt
    56401 ctggtgaacg catatcagct tcagaaacga tttcgatcaa aggcgtgcct tgtcggttca
    56461 aatcaacgta agaataaccg ccaataccat gcatgttttt tccagcatct tcttctaaat
    56521 ggacacgttc gatccggatt tttttctttt taccttctac ttcgatttcg atccatccgt
    56581 catgaccgat tggttgatca aattgggaaa tttgatatgc ttttggatta tctgggtaaa
    56641 agtaattttt ccggtcaaaa tgagtatctt tagagatttc acagtttaat gccaaagctg
    56701 ctttcatccc gaattccagc gcagctttat tcattactgg cagcacgcct ggataacccc
    56761 agtcgatcac gtttgtattg ctgtttggtt ctgcaccaaa atgagctggc gctggagaga
    56821 aaatttttga gttggttttt aactcgacgt ggacttctag tccaatgact gtttcaaaat
    56881 tcattcgtct ttccctccta aaatagctgg ttgttgttta tggaattctg ttgcttgttc
    56941 aaacgcatat gccgcttgat acatcgtttt ttcatcaaaa taattaccga tgatctgcaa
    57001 tccaactggt aatccttctg ataaacctgc cggtacagac atacctggaa gtccagccaa
    57061 gttgacaggg atcgttaaga tgtcactcat gtacattgtg attggatcgt taatgttctc
    57121 accgattccg aatgcaactg ttggtgaaga tggcccgatg atcaagtcat aatctgcaaa
    57181 gactttttca aaatctcgtt tgatcaatgt acggacttgt cccgcttttt tgaagtaagc
    57241 gtcataataa ccagcactta aggagaatgt acctaacatg atacggcgtt ttacttcttc
    57301 accgaatcct tctgaacgtg agttgacata tacatcatct aatgatttca cattttctga
    57361 gcgataaccg tagcggatac catcgaatcg ttgcaagttg gaacttgctt ctgatgaggc
    57421 aatgatataa taaacagcca caccgtattt tgaatgaggc aagctgactt cttccacaac
    57481 agcacctaat gaacggaatg tttctgctgc tttcaataca gcttctttta cgccaggggc
    57541 cacaccttcg cctaagtatt ctttaggtaa agcaatcttc attcctttga tgtcgcctgt
    57601 cagtccctct gcaaaatcag gaactgaaac gcctgaagaa gtaccgtctt tttcgtcata
    57661 accgctgata gctgtcaatg ctaatgcatt atctttcacc gtacgggtca ttggtccgat
    57721 ttggtcaaga gatgaagcaa aggcaatcaa accaaaacgt gagacacggc cataagtagg
    57781 tttcatccct acgatgccgt taaaagctgc tggttggcgg atacttcccc cagtatcact
    57841 acctaaagaa actggaattt gtccagctgc aactgctgct gcagaaccac cagaagagcc
    57901 accaggtact tttgttgggt cccaagcatt ttttgttttc ttgaaataag aagtttctgt
    57961 acttccaccc atagcaaatt catccatgtt tagcttacca acagggatca tatctgcttg
    58021 atagatttta tccatgaccg ttgcatcata aattggttca aaattgtaaa ggatcttaga
    58081 tgcagcggtt gtcaagatat cttttgttac gatattatcc ttgataccaa ttggaatacc
    58141 agcaaggacg ttgctttcat caatcccttt ttcatctaaa gcttttgcct gttccaatgc
    58201 tttttcttcg ttcaatgtaa tgaatgcttc gacctcaggc tctgtttctt tgattcgttc
    58261 aaatgttgct tttgtcaaat cttgtacagt gatttctttc gatacaagca tatgatgcag
    58321 ttcttctaga gaacgattgt gtaattctgt cattatgcgc cagcctcccc attatcgatg
    58381 attgcgggta ctttgataaa gccgtcttct gtttccggca catttttcaa taattcatcg
    58441 cggttccatc cagcttgcgc ccgatcttgt cgcatcacgt ttactgtttc aaccacattc
    58501 gacgtaaatg gaacaccttc tgtatctact tcttccagca tttcaaccat atcgatgatt
    58561 ttacctaatt ggtcggtaaa acttgcaagt tcttcatctg cgaacgcaag ttttgctaat
    58621 ttggcaacgt gtttcacttg ttcttcacta atcgccatac taccccttct ttctaaacga
    58681 gttaaaaact ttgctctcta ttttaacaca agagtgccgt gtctgaaatt gtttattgaa
    58741 atttgtctga aaaaactcat ttttcattct tctactgagc gacttttagc caatgcatct
    58801 gccatttgat cttctgtcca aacttcgatt cctaattctt gtgctttggt cagcttgctg
    58861 ccagcatctt ctcctgctac cacgatatcc gtttttttcg atacgctacc agtcactttc
    58921 ccgccaagat tttcgatcgt ctcttttgct tcttcacgag taaatcgtgt tagtttacca
    58981 gtaaggacta ctgttttttc tttaaaagga gactcgactt cttgcaattg ggcatttcga
    59041 agccctttgt attcgaaatt gacgcctgct tgttttaatt cattcatcaa ttcatggact
    59101 tcttcgttac tgaaataagt gactacactg tcggcaatga tatcaccgat cgtatcaagc
    59161 gcaataatcg actcatagtc acttttactc aatgtttcta gatcaccgaa atgttctgct
    59221 aaaatttttg ctgctttcgc tccgacatgt cggattccta acccgaaaat caaccgctcg
    59281 accgaattat ctttgctgtt gtcgattgct gtcaaaatat tatttgctga tttttctttt
    59341 attttgtcca acgtcaataa ctcttcttct gtcaatttgt aaagatcagc aacatctgct
    59401 actagttttt tatcatacat ctgttctagt acgcgcggcc ccaacccatc gatattcatc
    59461 gcatttcttg aaacaaagtg gttcaaacct tctttcattt gagcagggca tttaggattg
    59521 atgcaccgta aggctacttc ttcatccaaa tggacaagtt cacttccaca aactggacaa
    59581 tgtgtaggca attggtattc ttcgctgtct ttaggtcgtt tatctaacac gacttgcgaa
    59641 acttctggga tgatgtctcc cgctttataa atcagaactg tatctttcaa gcggatatcc
    59701 ttcaacttaa tataatcacc gttatgcagg ctggcacggc ttactgtcgt tcctgctact
    59761 cggactggtg tcatgatagc tgttggcgtt actacccctg ttcgaccgac tgtccattcg
    59821 atgttttcga ttagcgtttc aacttcttct ggcggaaact tgtaagctgc tgcccatctc
    59881 ggtgctttga cagtaaaacc aagttgatct tgtagcgaga attcattcac tttgatgacg
    59941 attccatcga tttcataggg caaatccaca cgtttgtcat gatattcttc aatgtatgac
    60001 cacacttcat caatcgaatg acatagacgt ttttcccgat tcgtgtggaa tccaattttt
    60061 tctagctctt ctagcgcatc atactgggtt tttgcttgca taggaccgaa atcagctact
    60121 gtgtataaaa aagtgtccag atttcttttc gctgtgattt tagaatctaa ctgacgcaaa
    60181 gaaccagctg cggcgttccg aggattcgca aagatatctt ttccctctgc ttctctgtct
    60241 tggttcaatt ggacaaatga ccgttttggc atgaaacatt cgcctcttac ttcgatgttc
    60301 attggttctt ttaatttgat tgggaccgac cggacagttt ttaggttttc agtgatgttt
    60361 tctcctacag ttccatcccc gcgagtcgca cctctcacga aatttccatc ttcataacgc
    60421 aaagaaacgg aaagtccatc tatttttagt tcacagcaat agtcaactac acgtcccact
    60481 gctttttgta cacgttgatc aaaagctatc agctcttctt tgctgaaaac gtcgttcaaa
    60541 ctgtaaagcg gaatatcatg agtgactttt tcaaaacctt ctaatacttt tccgcctact
    60601 cgttgagtgg gagaatcaga cgtgatcaaa tcaggatatt gttcctcaat tgctactaat
    60661 tctgcgtatt ctttatcata aacatagtct tccactgttg gtttatcttc tacgtagtat
    60721 tcgcgagacc attggttcag tcttgtacga agttcttctg ctcgtttagc agcttcgtca
    60781 atcgtcattt catgttccat catttaccct ccactactaa gctttttcaa ttggcgcaaa
    60841 ggcagccaaa agacgtttta ctccttgact tgggaaagcc acatctagtt ctagatcctt
    60901 cgacgtcccg cttactcgga cgactgttcc tagaccccat tttttgtgtt tgactttatc
    60961 tccaggtttc cagctgttat tttcccctcc agtagcactt ttagagggaa caaccgctgt
    61021 ctctggctgt ttatagctat atgctgtttt tttagcgaat acaggtgttt ttttaggcgt
    61081 aggacgcatg ccttcgattt ccagtaactc ctgatcgatt tcttctacaa aacgagaagg
    61141 tcggttatat tgcgtccgtc catataatgt tctggagaaa gcatttgtta aatacaacgc
    61201 ttcttctgct cgcgtgatcc ccacatatgc gagacggcgt tcttcttcca gttcgctttc
    61261 ttccatcaat gctcgagata aaggaaaaac cccctcttct agaccaatca ggaatacaac
    61321 tgggaattct aatcctttgg ctgcatgcaa agtcatcaat gtcacttggg aagcatcttc
    61381 ttctaaattg tcaatatcgg aaacaagtgc cagatcattt aagaagaccg ttagtttttc
    61441 ttctggtgca tcagcgtctt cttcattttg ctgttcgaat tgtttgtcga attcttgtgt
    61501 gaccgttaaa aattcctcca agttttcgat gcgtgcttgt gcttctaatg tattttggat
    61561 ttttaagtct tctagatatc cgctacgatc caaaacctct ttcgtcaatt ctgtcactgt
    61621 caagtatggg atcatctgag tgacttcttg gatcatctct ccaaatgcac ctaattgctg
    61681 tcctgctttt ccaccgatat ttgccagatc cacattttgc gctgcttcaa gcagtggcca
    61741 ttcatgaaga gaagcaaaac tgcgtagttt ttcgatagat cctggtccga tgcctcgttt
    61801 gggcgaatta acgatacgct caaaactgat tgaatcttga ggatttgcca gcacattcaa
    61861 atacgctaaa atatctttga tttctttacg atcgtagaac ttgtgccctc caaccatttt
    61921 ataaggaata tttgctttca acagagtttc ttccattaca cgagattgtg cgttcgtccg
    61981 gtacaagatg gcaaagtcgc cgtaattccg atgattgctt cgaatctctt cttgcatccg
    62041 atctacgata aaacgggttt cgtctcgttc attatctgca cggtagtaag tgatcttgtt
    62101 tccttctttg ttttctgtcc acaagttttt tggttttcga ttgctattgt tttcaatgac
    62161 ttggtttgct gcgctaagga tgtttttcgt ggagcgatag ttttgttcta gcaaaattac
    62221 tgcagcatct ggataatctt tttcaaaatc caagatgttc tgcatatctg caccgcgcca
    62281 gccgtaaata ctttgatctg catctcccac gacgcacagg ttcctaaatc tacctgccaa
    62341 taaattgact agcgtatact gtgcgtgatt tgtatcttgg tactcatcta catgaatata
    62401 atggaatttg ttttgataat atgtgagtga atcaggatgt tcttcaaata atcgaatcgt
    62461 attcatgatc aggtcgtcaa agtccataca ttgattatat tgaagctctt tttggtaagc
    62521 agcataacat tttgccgcaa tctcttcgta ataactgcct tgcatttttg caaaatcctg
    62581 aggggtctgc aggctgtttt ttgcttgaga gattgttcct aatatacttc gaggatcata
    62641 ttttttcgga tcaatgttca gttcttttag tatccgtttc atcaaggtca gctgttcaga
    62701 agaatcgatg attgtaaagt tccggttata cccgataaaa tcaacatctc ttcttaaaat
    62761 acgcacacac atcgagtgaa aagtcgatac ccagacatct tcgcctccag atgcgagaat
    62821 cgcattgaca cgttctttca tttcttttgc agccttattg gtaaaagtaa tcgctaggat
    62881 gttccaagga ttgacttctt tttcctcaat caaataggca atgcggtgtg tcagcactct
    62941 cgtctttcca cttcctgcac ctgccattag cagtaatggt ccgtcagtgt gaagaacagc
    63001 ttctttctga cgggggttca tcccgtttaa taattcagct ttggatgaca ttaacaacat
    63061 cctttctttt atcaatcttg ttaattatag cattttcttg gctttcatta aactagctag
    63121 ttcaaaatca tttgtttctt tttatggatt tttccttgtc aattcgttga tttcgcgcta
    63181 aattaaaaga aagcgaggcg tttgaatgga aaaaaaagga aaaatcaaga aattagataa
    63241 gactcagata tattttattc taaaaggaat atttgttgga ctgctgacag gaatcgtcgt
    63301 tagcctgttt cgattatcta tcgaaaagct aagcgattta gttcgaagta tctatgaaat
    63361 gagtcgggaa cagccgattt acttaattgg cctagctatt tgctgcatcc ttgcagcatt
    63421 tttcgtgggt tatctggtca aaaatgaacc ggatatcaag ggaagcggga ttccacaagt
    63481 agagggacag cttcgcgggg aattatcaat gaactggttc tctgttttat ggaaaaagtt
    63541 cattggcggt gtactttcag ttggtgcggg cctttttcta ggtagagaag gaccttctat
    63601 acagcttggc gcatccattg gacaaggagc tggacaattg tttcggagtc catcttcaga
    63661 agaaaagatt ttaatttcta gcggtgcaag tagcggactt gcagcagcat tcaatgctcc
    63721 tatcgcagga ttactctttg ttttagaaga aatccatcac tccttttctc cacttgtttg
    63781 gctgacatca tttgcttcag caatcactgc taacttcgtc tctctttact ttttcggctt
    63841 gagacctgtt ttatatctag gtgaccttcc ttctttgccg ttgaaatatt atggttcctt
    63901 agtgatctta ggagtacttc taggcatctt aggttttatt tatcagaagg tcttgctggc
    63961 tttgccaaaa ttttacaacc gattgccttt accagcttat tttcacgggt tcgttccttt
    64021 cttgctgatt ttgccaattg gttatttatg gcctagtact ctaggcggag gcaatcaaat
    64081 cgttttagct tttggacatg cttccttgcc aatcattatg attatcggtt tgtttgttct
    64141 tcgattcgtt ttttccatga tttcttacgg tggtggtctt ccagggggga ttttccttcc
    64201 gatattgaca ttgggggctt taatcggtag cttttatgga aacattatgg ttgatttcgg
    64261 gatggatcca atctacatca aggattttgt cgttattgcc atggctggtt atttcacagc
    64321 gattggaaaa gcaccgctga cagcaattat tttagtgaca gaaatggttg gctctcttaa
    64381 tcatctgatg cctttaggat tggctgctct tgttgcttat atcgtcaatg accttctcgg
    64441 cggtaatcca atttacgaat cattattgga acgtctactt ggaaatactc agaccgcctc
    64501 actaaaaggt gcaaggacaa cttttgattt tccagtaacg gcagagagtt ctttagacgg
    64561 attaatggta cgagacttca attggcctaa aaatatgctg ctaatctcta tacgcagagg
    64621 aaatcaggaa atcttgactc acggtgatac gatcatgaat gtaggagata ttttggttat
    64681 cttgactgat gaagcaaact tgccaagaat caagcaggaa atcgaggcta aatcttctat
    64741 cacaaatttg aagcaatcat tttaacgaac atggaaaaac tattttacaa caactattca
    64801 tctacactac ttgattctat atgattctat aaaaaaagaa gagactggga aaaaccagcc
    64861 tcttcttttt tatttctatg cttctgctgc tgcaggagct tttctcaata aaccataaat
    64921 cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg ggtgactcag
    64981 taagaataca acgaaaatcc cgccatgagg agccagtaat ttgatcccga aagctccgac
    65041 taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa tcgggtcagc
    65101 tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga tgttcgtcaa
    65161 accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag caacgaaaat
    65221 tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac ttccgccagt
    65281 tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt tgattggacc
    65341 gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag cattcgaacc
    65401 actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag ggacattgac
    65461 cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga ggatcgtttt
    65521 aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata cgatgacata
    65581 accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg tattagctaa
    65641 tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg aagcaataaa
    65701 tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt tgaaccagct
    65761 agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc caataaattg
    65821 gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag gtaacatgtg
    65881 tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat ccgcatttcc
    65941 ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac cactaagggc
    66001 tagattgatc agctcttctg gtttacggat accatcactg acaggacgat tgatcagttc
    66061 ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta caccttctgc
    66121 acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt tcgtttcgac
    66181 tttgatctcc acacccattt ctttcgcttt tttcttcaga gcatcttctg ccatgtaagt
    66241 gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt ctggatgagc
    66301 agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt tttgctcttc
    66361 agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta attttcctac
    66421 gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat gtgtgtcgtt
    66481 tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt ctaaggcttc
    66541 ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa ctgcactgtt
    66601 tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg cttcgcgggc
    66661 tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa acattttttg
    66721 gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga tcatcgcttc
    66781 tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc aatttttgtg
    66841 atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc atcagaaaaa
    66901 gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc tttcgtacgg
    66961 ctgtaagccc caataaagcc ggcaatcatt gaatcccctg cacctactga atttttcaat
    67021 gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa agcaccgtct
    67081 ccagccattg agatcagcac attctgtgcc ccttcagcta gcaatttttt accatacgga
    67141 atgatttctt ctacagattg gaaggttgta ttgtaaagct cagctaattc gtgattgttt
    67201 ggtttgatca acaatggttt cttaacaagt gcatttttta ggtcatcacc tgttgtatca
    67261 atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata aaatcctttt
    67321 cgcaggctag ccggcgcgct tcctgacaat acgacgatat ctccttgtcc tactgttcct
    67381 aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcccaa accgttaatt
    67441 tcagtttcag tatctgattt tagtttgata ttgattcttg tatcttcttt tacggttgtg
    67501 aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc agtgaaccct
    67561 cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg ggaaacattg
    67621 atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc gcctagtttt
    67681 aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt gtaaatcatt
    67741 gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct aatggacaac
    67801 gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac aactggttga
    67861 atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct aaacgtttaa
    67921 cagctgcctc ttctgggtcc ggagtcgtga atccttgttc aagatgggca ccgttcattc
    67981 ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta gatcctaaaa
    68041 cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc tccaaatcaa
    68101 ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt ccttgcagaa
    68161 aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct tcgtcattaa
    68221 tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg agtgattttt
    68281 cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca tgaactcttt
    68341 ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat tcagaagcat
    68401 taaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc aagtctagga
    68461 ttttttgtct acgttcctct gtaagcattt tcacgatcac ctcaatacaa ataatagcat
    68521 attttttttc tactcgcaat ataaatcagt caaaaacgtt cataaaaatt ataaatcagt
    68581 caaaaaaaaa taaaaaacca gtcaaaaaga ctggtttttt atttttttgt ctatcatcaa
    68641 gccgttttat cgttttttat tttcgcttct tgtttttttc atataaacag aagcaggttt
    68701 tctttcctta tgaagaagat aataataaag tcccatcccg ccaaacatga ccaaaaaacc
    68761 gatgactgat cgaataggaa aattaggaac aaaaaagaga cagacggata ataatgatgc
    68821 cggaaccatt attcgataat agagttgttt atccattttc ttcacctcat attttttgta
    68881 aagtaatcaa ttgttctaat tctcggtaat ctaaaaattg cacacgcaga tgctgctcac
    68941 ctttcttgac atcgaattgg atacttcgcc gctttttctt tattcgtttg aaggtaacat
    69001 cagagagtct atgtttgatt tcctttaacg gtaattctga cagggattct gaaggaacat
    69061 agattcttaa ggataaaaga tactcttgat atttttcatc tgttacctct acttctagat
    69121 attccctaat ataataacaa taagcttcga ttccattatc caaagcaaca gtcggatcga
    69181 taactttata gcacatcatg cgcgagcgat tctcgtcaac ccaaggaaaa tacgcctgag
    69241 catttagtgt tccgcgaaca cgcctttctt tataatctcc ttgttgaata tcataacttt
    69301 ttgttacaaa aaatgaagca ttctttttag gaacaggttg catttgtgca ttctgatact
    69361 ggacagattg gatcgtatgg tcagtgtaaa tgtattcaac gaatggcggt ttcaataaac
    69421 cgacaccatt gtcccaagca agatgatcaa acccaagctg gtccctaaaa taggattgaa
    69481 acatttgatt gtttggcttt tgccagttaa aggggtctcg ataaagctgg atacatatga
    69541 cttcgttttc taattccttc actttttcta cttgttggat gtcgagaaaa atcggtttag
    69601 ggatgatttg atgataatag cgactataat acatttccca acacgaagtg aaacataaac
    69661 cttggtaaaa aagatcgtat cctggaaatt ggttgcaatc gactactact tccccgtttt
    69721 gttgtttcat tttaggtaaa tgttcgattt catccttttt ctcaaacaat agccgttgag
    69781 agatctgttt tgtattgtga tagataaact cgctataagc tcgcatatag gcgaacaccc
    69841 catgagcaat catttttttc tgaatgaagt ctcgaatcaa aaattgcttt tctttgaaaa
    69901 cagagataga caatacattt tttatcaata attgattatc ttccaagcga aaactacatt
    69961 cgttctcgtc atttcctaca actaaccaac tttcgtctct taccgatgct agcattattt
    70021 tttcttgaag ctttcgaaga tcatacggat ccgcttgttg tgtgaaagag cggataaatg
    70081 ttggctggat caacagacgt gtcaaaatag cccaatcgct tatttcctgt tttttttctt
    70141 cttcatttaa gtctgtgagc tggatagtca tcaataattt atcttcgcca atcattttct
    70201 cacctcttta aaatcttttt ataatttaat tataaccaac gataaagaaa aactaaaact
    70261 ttatgtctta gaaaccaatt tggacgatta catgatagac taagtaaaaa gaaacaaaga
    70321 ggtgtttaca atggggttga aatttgaacg tacagataat ttagataaac ttttcgaatc
    70381 atttgctgtc gatccggaaa aaacagttgc accaaaagaa gagatcgatc gatttctaaa
    70441 accacagcca caaaatgaaa agaaaaaaga caagaaacaa aagtaagtta agctcaaaaa
    70501 aagacttacc agccaaactt ttatgaaaga gtttgactgg taagtctttt ttattctttt
    70561 tatgattcaa ttgcttgttc gattgctgcc cacgcttctt cttttccctg ttttgtaacg
    70621 gaagaaaaga gaataaacgt gtcattgcga tcaaaatcca acgctttttt gatttcgctc
    70681 tcatgcttgt tccatttacc acgagggatc ttatctgcct tagtggcaac aacaattaca
    70741 gggatatcat aatacttcaa aaattgatac atctggatat cttcttgaga aggcttatga
    70801 cgcaaatcta ctaaagaaac gaccgcacgt agctggtctc tagtcgttaa atatgtctcg
    70861 atcatctttc cccattttgc tcgctcagtt ttggatactt ttgcataccc atatcccgga
    70921 acatcgacaa aatgtaatgc gttctcgatc aaataaaaat tcaatgtctg ggtctttcct
    70981 ggcttaccgg aagtacgggc taaattcttt cgatcaatca atgtgttgat aaaagaagat
    71041 ttccctacat ttgatcgtcc tgccagagct atttctggca attgtgtatc tggatattgt
    71101 tttggtgcca ctgcacttat gataatttca gcttgatgga ctttcatggt ctctctcctt
    71161 aacaaggtga tgaataaagc aagcggctgt cgcaaaagcc aaaatgactt ttacggcagc
    71221 ctcttttcat caacccgctt ttttctctga atctttatag attactgttg gctcaccaga
    71281 caattcagct gcttcttttg tgataatcac tttttcgatg ttttcatttg aagggatatc
    71341 aaacatcaca tccatcatga tttcttcaat gatggaacga agtcctcgag caccggtatt
    71401 gcgttcgatt gcttttttcg caatggctct caacgcttca ggttcgaatt caagttcggt
    71461 attatctaga gaaagaagtt tttgatattg tttgactagc gcatttttcg gctcagtcaa
    71521 gatccgtacc agatcatctg ttgtcaattt ctctaaagct gccataacag gtaatcgtcc
    71581 gataaactca gggatcaatc cgaattttag taaatcttca ggaatgatat gctgcatgac
    71641 actttcgtct tcagaaagtt tttggttttg tgtaccaaat ccaatcgtct tttcgcccat
    71701 acgattcttc acaatcgttt cgatgccatc aaatgcacca cctacgatga acaatatgtt
    71761 cgtcgtatca atctgaataa attcttgatg tggatgttta cgtcctccct gaggtggcac
    71821 gcttgcaaca gttccttcta gaattttcag caaggcttgt tggacacctt cgccggaaac
    71881 gtcacgagta atagatacat tttcgctttt acgcgcaatt ttatcgatct catcaatata
    71941 gatgatccct ttttctgcac gttccacatt gtaatcagca gattgaagca atttaagcaa
    72001 aatgttttct acatcttccc ccacataacc agcttctgtc aaacttgtcg catctgcgat
    72061 tgcaaaaggt acattcaatg tttttgctaa tgtttgtgct aaaaatgttt taccagaccc
    72121 tgtaggtccg atcaagcaga tattgctttt ttgcagttca acatcatctg tgttttcttg
    72181 tgcttgctga ttgacacgtt tatagtgatt gtatacggca acagctaacg agcgttttgc
    72241 gcgatcttgt ccaatcacgt agttattcaa tacttcaaga atttctagtg gtttagggac
    72301 ttcagtgaat tcgcgtacag cttcttcata aaattcttca tcaatgattt ctttacatag
    72361 gtcgatacat tcattacaga tgtagacccc tggaccagct acgatctttt tcacttcttc
    72421 ttgggttttc ccgcaaaaag aacagcgtac ggtctcattg ctacttggat tgtcatacat
    72481 ggtcttcacc ccttaacttg caaaaagtat gcaagaaact atcaaagact ttacagtctt
    72541 ttactatcat aacatagttt agtaaaaaga aaaagtgttt aacaaaggat caactgacct
    72601 atacctttgc attttttact cttaacaaaa aataaggaac tgtgacaaaa tcgtgtcaca
    72661 gtcccttatt tcgaataaac aattttctag aagtagcttc ttcagaaatg atttattact
    72721 tgatttctat tctttcgctt ctgtcgctgt acctgtgatc aattcgattg cttttttcat
    72781 tgtcacatca tgttccagca tatcttctgt caacacgcgt ttgatttgtt cgattggcat
    72841 gttgtatgtt tctgataatt cttggatttc tgcattgatt tcttcttctg ttgcttgaag
    72901 attttcagca gctgcaattg cttcgatcac aagatttgtt cttgtgcgca tttctgcttc
    72961 accttcgaat tgtttatgca agtcttcttc tgtagaacca gttaattgat agtacatttc
    73021 aggagagata ccttgacgtt gcatgttgtt caagaattcg tccattgaac gatgtacttc
    73081 atcatgaacc atcacgtgtg gcaattcaac gatttctgcg ttttcaacag ccatacggat
    73141 cgctgcttca tcttttgcat cgtccgctgc tttttctttt gtttctacta attctttgcg
    73201 atatttttct ttcaattcgt ctaatgttga tacttcgtca tcaacatctt ttgcgaattc
    73261 gtcatctaat tcaggcactt cttttgcttt tacttcatgg attgtcactt tgaagactgc
    73321 ttcttttcca gcaagatctt ctgcttgata atcttctggg aaagttacat ttacatctag
    73381 actttcacct gatttatgac caactaattg atcttcaaaa cctggaatga atgagcctga
    73441 acctaattca agtgagtaat tttcgccttt tccgccatca aacgcttcgc catctacaaa
    73501 gccttcgaag tcgattacta ctgtatcgcc attttcagct gcagcatctt ctttgataac
    73561 taattcagct tgtgcttctt gttcacgttt gatacgtgca tccacgtcag catctgttac
    73621 ttcacggtct tgtttttcaa caactagatc tttatattgt cctaatttta cttctggttt
    73681 cactgttact tcagcagtga ttacccagtc ttgacctttt tccatgcttt caacatcgat
    73741 ttttggttga gaaacaggat cgatgccagc ttctttgaca gcagcttcat aagcttctgg
    73801 taatacagca ttcaatgcat cttcatataa agcttcttca ccgtacatac ggttgaatac
    73861 ttgacgagaa actttccctt tacggaatcc aggtacgttc aagctttttt tcactttatt
    73921 aaacgcagtt gttaatcctt tttggatttc gtcttgcgca atcgtaaatt ttaaaacacc
    73981 atcattcgtg cctttttttt caaatgttgc agtcatttaa ttccctccga gtttagaaat
    74041 tcattttata catcaaaaac gtttcatgca tacctttaaa tagtacacta accctttcaa
    74101 attgtaaaca tattgaatgg atagaatcct tgtttttcat aacattttta tctttttcac
    74161 tgataaaatc taatggaaga agatcatttg ctgcaaaatt ttttctcttt tttttaaaaa
    74221 atcttgtttt tcatcttctg taccttcata catcgttttt cctgtacacg cctctacagt
    74281 cagttgaaac cagcgcttcg ggtcttcgat gtatgtatca tagacaggat aaacaattgc
    74341 agattgcaac gtgaattctt catttaacac ggaactaagc agcgcatctt cattaccgta
    74401 acgatctgaa aatacacata attgctggta acttgcctgc tgctgcggct ttggcagatc
    74461 ttttggtatg actttgacta acttttcttc aatcgtcaaa tagaaaacag gatggcattc
    74521 gttcaattgc ctaagtgtct ccagtaattt tgcccttgct aaaatatgga cctctggcga
    74581 tacaataagt ttactcgctg tttggataaa ctcatgataa ggaagctgtt cgatctcatc
    74641 aatagacgca agctgacgtg caggttccaa cgaaggaagt tcctccgatt tattgtggag
    74701 tgccttgatc ttctgcctct ccatttgtcc ggataattct tctgcaaatt ggattttttc
    74761 aatgacccgc tgctcgaaag cttcataaaa atctgtactt gctatcaatt ttctagcata
    74821 taaaaaatct tgtgtactga ttaacaagtc aaaataaaat tcagcaaact cctcattttg
    74881 aagatactgt ttttcatgca agagtgcttg cttcaatgct tcttttttct cgtccaactc
    74941 gtaaagacaa aaaacaagca ggctattagc ctcaaagctt tctttcaact cgtaagctcg
    75001 ttgaaataat tcttttgcct gctgatattg ctggtttgct agtgcttgtt gtgctactcg
    75061 cattaaattc tcatattttt ctggaaaatc aatcggcttc acgcagtgtc ctcctcttgc
    75121 tcatgttcag ctcatgttca atagtagcaa aacaaaaaaa gcatgacaat taaaaataac
    75181 tgaagcaccc tctaaaagct agattttaga tctgactttt agaaggtgct ttcaactgtt
    75241 actgcttttt attgctcatc agctgttgac ttcctggttg aatgctttga tcagattgat
    75301 cgtaacaaca cttgtattag tgaaaaaatc gcctagatgt tgctttttct gattaaagat
    75361 tgctggaaga taccctaaca tcagcaaagg aaattttaga atgaaccggc aagcaccttc
    75421 tctaactaaa acggttgacc agctaagttc ttcttcatca aagctgatga ctcgaatacc
    75481 aaagatcatt ttcccaatcg tttgaccatg attgaatttc gtcaataaaa taaaatacgc
    75541 tagataaata agtaaggctg tgaatccgta gatactcaga taagaatctg aaaaattaag
    75601 ccaacctaga tttttggcaa taccaagtgt taaacgcgta atagctccga tacacaaaag
    75661 atcgaccaag aaagcaaaca ttcggataaa aaaacctgca tagaaatact taggaaaatc
    75721 atttgctttt ggcggttcat ttcttgtgtc cgtatacttt ttccatttac gttgtttctt
    75781 tttgatttct tcgggcgtca aaggctctct ttcaaaagag ctcagtacct tttgggaaaa
    75841 gttggagtca ggtcctacag caggctgctg ttgcttatct ttttcttgtt ccttattttc
    75901 atttgaaagc tctgacatgc ttactcacct ccgtaataat acattgcttt tggtgattcc
    75961 gctgtcccta gattctcaag aacggataag atctgactag tctcagaagg cttcaatccc
    76021 tggaattctg ctagtttact tcctaaccat gtactagcaa acccagatgg cgtggaagaa
    76081 tattctacta gttccgcatc ttcaagctgt tgttcctttc gcatagcttt taaagcatct
    76141 tcaggaaatc ccaattcatc gactaaacct acttcttttg cttggacacc atcataaatc
    76201 cttccatcag caattttttt gacttcttct tcagatttat tccgtccctc gctgacgatt
    76261 gctacaaaac gactatatgc gctgtcgata tatgcttgaa gcaccgcttc ttcttctttt
    76321 gtctctggtc gcgttcctga acccatatct ttcaacgctc cgcttttaac tgttgtatct
    76381 tccacaccca gtttttctag aagtcctgaa taattcaatc ctgacatgat cacaccaatt
    76441 gagccggtca ctgtttcttc tgttgcaaag attttatctg cttgagcaga aatatagtag
    76501 ccaccgctag ctgccatgtt tttcatgctg acatacattg ggatatcatg ttctttacga
    76561 atcgtatcca atttcttagc gatttccgca ctttcgtaga caccgccacc aggagaattt
    76621 acttctaaaa agataccttt gactgttgga tcttcttcaa tcgccttcag ttgttccata
    76681 aaatttttat gattgtaacc ttcagaagca aataaacctg aagaccctcc cgcagcaatc
    76741 gttccatcta ctgataattt tacgattttt tgcgtactgt ctccctcttc caacacattt
    76801 gaagctagtt cttcatcccc atataaccaa ctgttcaatc cctcaatttg atcgttttcc
    76861 tgaggcttag tcaaactagc tgaaactaac gaaaccacaa ataatcctgc agcaatcaga
    76921 actgctgccc aacgtctctt attcattctt tctcctttct aatacaagtt ttttatgacg
    76981 atcacagttt ctgactgctc agaagtgtcg aaccgctctg ctttttcttc ccgcgcatac
    77041 ccggaaaacg actcttttgt caattcatct tctaccgtaa actcacgagc ttcagcaact
    77101 tccaaggcat caggtgcgat ttcttggatg ctatcccagc cagtatctaa aaatattttc
    77161 gtatcatctg atacaccagc tgatgcttcg aatttggaca attgtttttt taacattccc
    77221 agtgtcatga tctcaatttt tgaatccatt tttactcctc ctctatccga ttactttcta
    77281 ttgtaccgaa ctcctgaaaa agatgataga taaaaaccca ttattttttg acataaaaag
    77341 agcatttgac aaagcatttg atatatacca atttattttt tattcttttt ttgttgacaa
    77401 gaacattcgc aaaaggttat gattttaaat gtttccagat aaaaaacaaa agaggaggat
    77461 agttatacct tttaggatag cgccaggtct gtgtaaacag atgacgagga gagggtttat
    77521 cgaaagattc ggcggatggc cctagggact gcactctaca gaaaatccac aaaaaatatc
    77581 tgcaaagata aaacaaaagg attttcctgc agctggaagc attcatacga attcattata
    77641 gaaagtagga tgttttttat gtgcggaatt gttggaatga ttggattaaa aaatgtaaca
    77701 ccaggattga ttgacggtct agaaaaatta gaataccgtg gttatgattc agctggtatc
    77761 tttgtctcag atggcacaac tgattatctg gtcaaagcac aaggcagaat tcaaaatttg
    77821 aaaaacaaaa taaatattga tactacagga aatataggta ttggtcatac acgctgggca
    77881 actcacgggc aaccttctga agaaaacgcc catccacata cttcccaaag tggacgcttc
    77941 gtgctcgttc acaatggcgt aatcgaaaac tttgaagaac ttaaaattgc ttatttagca
    78001 aatgaccact ttattggtga gaccgatact gagattatcg ctcatctaat tgaaactttc
    78061 gcgaaggata ctacaacgca agaggcgttt ttaaaagctt tgcgggtcat caaaggttct
    78121 tacgctttcg ctttgattga tcggacagca cctgatgtta tttacgtcgc taaaaataaa
    78181 agtccactat taatcggact cggcgatgga ttcaatgtga ttgccagcga tgcaatggct
    78241 atgcttgctc atacgaagga attcgttgag attgaagatg aagagatggt taccgtcaca
    78301 tcagaaaaag ttattattca aaattttgca ggtgacatcg tagaacgttc ttcattcgaa
    78361 gcacaagtag attcttcaga tatcgagaaa ggtacctatc ctttttatat gctgaaagaa
    78421 atcgacgaac agcctattat catgcgtcgt atcgctcaaa aatacgtaac agaagacaat
    78481 cgtgtctctc ttgatcaaaa gctggtcgat acattgtctg atagcgatcg aatctatatc
    78541 gttgcttgcg gaactagtta ccatgcgggg ttagcaggta aacagactct ggaaaaattg
    78601 acacagatcc ctgttgaggt tcatttagcc agtgaatttg gctataacac acctcttctt
    78661 tcaaaaaaac cattctttat tttcttgagt caaagtggcg aaacagcaga tagccgccaa
    78721 gttctggtaa aaatcaaccg tctcggctac ccttcactta cgattacaaa tgttgctggt
    78781 tctactcttt cgcgggaagc atcctttaca ctgctattgc atgctggacc cgaaatcgca
    78841 gtagcatcaa cgaaagctta tactgcacaa atagctgtac taactttatt agccaaagct
    78901 atcggtgata aaaaagaatt tgaaacttct cttgtattcg atatcactca tgaattgagt
    78961 ttagttgcta atgcgatgga atcggtcatc gcccaaaaag attatttaga agagttggca
    79021 gaagtatatc tcagcgatac aagaaatgcc ttttacattg gacgtggcgc tgactacaac
    79081 gtttctcttg aagctgcttt gaaattgaaa gaaatcagtt atatccaggc agaaggtttt
    79141 gccgctggcg aattgaaaca tggaacgatt gctttgatcg aagaaggaac accagtgatt
    79201 ggaatcatca gtgaagaagt gactggtgcg catactcgag gaaacctgaa agaagtcgaa
    79261 agccgtggcg ctaaaacact agttattgtc tcagagggat tagaaaagga aagtgaccag
    79321 ctggtgctac caactgtcca cccttatcta actactctaa ccacagtcgt accgactcaa
    79381 ttacttgcat attacgcaac gctattacgg ggattcgacg ttgacaaacc acgtaattta
    79441 gcgaaatcag tgacagtaga ataataaaag aacaaggacc agtgtcagac atctgacact
    79501 ggtccttgtt cttttatttt ttatgaaaat atctcttaat ccagtccgat ttcttctttg
    79561 actactgccg cgattttatc gacatagtaa ttaactttct catcagtagg cgcttctgcc
    79621 atcactcgaa gtaatggttc tgtaccggaa ggacgaacta ggattcttcc ttctgatccc
    79681 atttcagctt ctgcctcttc aatcactttt ttgattgccg gaacatccat cgcaccgttt
    79741 ttatcactta ctcggatatt cactaatttt tgcggataga ttgttacctc tgctgcaagc
    79801 tctgataatt tcttacctgt ctgtttcatg atattcagta actgaattcc tgaaagcatc
    79861 ccatctccag ttgtgttaaa atctaagaaa atcatgtgcc cagactgctc gccgccaaag
    79921 ttataatcgt ttttgcgcat ttcttctaca acgtaacgat caccaacttg tgtaacgaca
    79981 tctttcaaac cgattccttc caccgctttg tggaatccta agttactcat gacagtcgta
    80041 acgatcgtat cttttttcaa tcgatttttt tctgccaagt atctagcaca gataaacatg
    80101 attttatcac cgtcgacaat gtttccaagt tcatccaccg caataatacg atcgccatcg
    80161 ccatcgaaag ctagtccagc atctgctcct ttttcaacga ccatctcagc taaacgttct
    80221 ggatgggtag agcctacgcc atcattgata tttaacccgt ctggatttgt gcccatggta
    80281 taaaaatctg tttcaagatc ggcaaacaaa cgattaacac ttgttgaagt tgctccgttt
    80341 gctgcatcga cacaaatggt caaaccggaa aggtcaccgt tgatcgtttg tacaaggaat
    80401 tgagaatatt tcaataagcc ttctggaaat tcttctacag ttcccaatcc ttcagctgat
    80461 ggacgaggca attcatccac ttcagcatct aataatgctt caatttctag ctcttggtca
    80521 tctactagtt taaaaccatc tgcaccgaaa aatttgattc cattatcttg tgctggatta
    80581 tgagaagcag aaatcatgac ccctgcgctt gctttttgca aacgtgtcag ataagcaaca
    80641 cctggtgtag agatcacacc tagctggaac acttcgatac ccaccgataa aagtcctgaa
    80701 atcagcgctt cttctaacat ttgacctgag attcttgtat cccgccctac taacacgcgt
    80761 gggcgttttc cttcttcttc atgctggctt aggacataac ctccgcaccg tcccagctta
    80821 aatgcaagtt ctggcgtaag ttccttgttg gcttcaccgc gtacgccgtc tgttccaaaa
    80881 tatttaccca tagttgtaaa attactcctt taacttaatt ttctgaggaa tttgttctgc
    80941 tcatttgtgt tgattcgctt gtttctgatg tttcttctgt acttgtggtc gagctgcttg
    81001 tcccagattc cgaactggaa gaaatggttg ttgtcgatgg ttccgttcct gaatcagcag
    81061 atgaaatact tctactcgta cttgtatttt cttgtgtccg actgctcgtc gaagcagagc
    81121 tactgcttga cgtttgcaac acgggtgtaa tctccacact aactgattcg ggcttgatac
    81181 ttaacccctc ttctactggt atttcaattt tacgagttgt tcgatgattg atacctgaga
    81241 cattgatcgg tacagcaata ctgtcaccga tcgatgcaag caaatcgcta gagccgctta
    81301 cttctgcttc cagttttgaa aaactgaaat catagctttc taccccggca gctggtgttc
    81361 cttgctgtat cccataaagt cgtaccgact tgcttggctt gatcgaatca gctctcactg
    81421 ttacttgcac tggatcagag acgatactta atacttcccc tgctgcattc agcgcctgta
    81481 ttgggacctc actattaatc ccatcatctg tgaccatcga agcgtccaca tcagctacta
    81541 ctcgtttgat ttctgccaat gttttgtcac ctgtagtgat agagactttt ttaggactaa
    81601 cggaagtatc atcaagttca tatccagatg gtgtgaacgt tgaaggaatc aacgtttcca
    81661 catcgaaatc ttttattacc tttttctcaa ccgttactgt aatagtcgat ggttcgatct
    81721 ttgctgtgac agcactgctc aaattttgaa tttttagcgg aacctcatgt gttccttcgc
    81781 ccagcttagt gatatctgct gtgacgcgga acatccgtgt atcttcgttt gcctctgcat
    81841 tcaactgaac tcggtttgca ctggaaagtt tgacagtcac tgcattttca tatccatgga
    81901 tatagtagcg ctttgaatca taagaaatct tgattggcac cccagtaact gtttgattat
    81961 acgcttcatt tccagaaagc gtatttggaa cggactggcc atttgcattg aagtacagcg
    82021 caatactgaa cagcaatgca ataaaactgt aaagaatgct tgtccgtttc tcttttgaga
    82081 tcatttgcga tcccctccct tagtcatacc gtctaggaaa gattgaatca cgtttttctt
    82141 gttttttgtt ttctcttcag caatcagttc tctacgcaaa attgccaaat attcttgctg
    82201 ggataagcca gccatcagtt cattatctaa tgtaatgctg acatccccag tttcttcaga
    82261 gacaacgatg gtaatcgcgt cgctgacttc gcttataccg acagctgccc ggtgtcgagt
    82321 cccgaattct tttggaatca acatactttc tgatagagga agataggcgc ttgctactgc
    82381 gatctttcct tcttttacaa taactgcacc gtcatgcagc ggtgtattag gaataaagat
    82441 attgatcagc agctctccag tgatatctgc atctaatgca attcctgtct caatatactc
    82501 atctaatcca gtatgccgtt cgatagtaat tagcgcaccg atttttcgct tggacatata
    82561 ttggatggct ttgtcaaaag acaagatcat cttctcatct tcctgctgtt cgctttttga
    82621 ttgtttgaaa agcgaactgc gtccaagatg ttccagtcct ctccggattt ccggctgaaa
    82681 aatcacgata gcagctatca ccccgtacgt aatgacttgg ttcatcagcc aagacaaggt
    82741 gtgcagacca atgatttccg ctacgattcg gataacaata aaaatagcta cacctttcag
    82801 aagctgaatc gcttttgtgc ctcgcagcag ttggatcagt ttgtatacaa gataccagac
    82861 aaccagaata tcaagtatgt tcaccaaaaa attcagagag aacaagtcac cggaaaacat
    82921 ttgctgccaa tagtccaaat taaaaagttc cccgatttga aatgacataa aaagcctctc
    82981 ttctcttttg agatttcctc tctagtatat catatgtttt aattttagag gctgatctgc
    83041 tcgtattttt cttgagaaaa acgcataatt ttcaggaaaa ttgcaagtat gcgttttatt
    83101 tttctctgca ataaatattt ttaaacttca gagaattatt cattatattt tttctgttat
    83161 ttttcctttt tttcttttgt agcttgttcc atttttttac gtcgttctgc tctggcagct
    83221 cttctttctt ctgcttcaag gtccgtcgtt ttttcttttc tagtcttaac gggtacatcg
    83281 atagattcct ctggttcaag tcgtttcttg attttttcta attctcccgt cagtgcagca
    83341 tagttgtaaa aacgtgtttt agcgtcttgg atagtctttt caaataaagc ttttgcaaga
    83401 tttggatttg cgttctctag cgaggaaaag cgaacttgtt tcctcatgaa atcaggcata
    83461 gcagagaaat caggtttttt gtagtccaaa gtcattgggt tcttgttttt ttcgaccatt
    83521 gcagggttat atcgatataa tgaccaatag ccagaagaaa cagcttcttt tgcttcttta
    83581 agcgattctt tcattccacc aagcaaacca tgtgtgatac aaggcgtata ggcaatgatt
    83641 aaagaaggtc caggatactt ttctgcttct tcaaaagcct ttatcgtctg catttgattg
    83701 gcacctgaag caatttgcgc cacataaaca tttccatatg tcatcgccat cattcctaga
    83761 tctttctttg aagcatactt tccactagcc gaaaatttag cgattgccga agctggtgtt
    83821 gcttttgagg tttgaccgcc agtattggaa tagacttcgt tatccaaaac aagaatattc
    83881 acgtctgctc cgctggcaag tacatgatcg atcccgccaa aaccaatgtc gtaagcccat
    83941 ccgtctccac caatcatcca ttggctgttt tttacgaata gatcctttct cttgtatata
    84001 tcctccagtt cagggacaat tgatcgttcg ctttcgatcg cagcttgcag ttttgctgct
    84061 ctttgctgcg ttccttcgct ctcaaacatg tgtaccaacc agtcttccat caattctcgt
    84121 agttcttctg atacttttgg caatacttct ttgattgaac ttgccaaagc ctcgcgacga
    84181 gtctgtgccg ctagaagcat accataacca aattcagcat tatcttccaa taaagaattt
    84241 gaccatgcag gcccttgacc acattcattg gtcgtataag gagaagcagg agaagcaccg
    84301 ccccaaatag aagaacagcc tgtcgcattc gcgatcatca ttcgatcacc gaacatttgt
    84361 gtcaataatt ttacataagg tgtttcgcca cagcctgagc aagcgcccga gaattcaaga
    84421 agcggttgat tgaattgtgt agacaagaca gtattctttc ctttgactgg atttgctttt
    84481 tgtcttaatg tcattgcaaa agcccaattc acagcttgtt ctttctgttc ttcataaggc
    84541 ttcatcacta aagctttttc ttttgcggga caagcctcta cacacagacc acaacctgta
    84601 cagtcttcca ctgaaacttg gatacggtat tttacgccgt ctgcgcctcg catttctctc
    84661 acgataaatc cttctggcgc ttcttccatt tcctcttcat ctgctaaaaa tggacggatg
    84721 gcagcatgag gacaaacaaa ggcacattca ttacacatcg tacagcgatc actaatccac
    84781 tcaggtactt ctaaagcgac gccccgcttt tccatagaag ccgttcctaa aggcatttcg
    84841 ccagttgtca ttccatttgc tacaagtgta ccaacagaga gttgatttcc ttcctgtgca
    84901 ttcactggtt caagtatttc ttgtatataa ccagtgttcc ttttattgat tttttcaggc
    84961 atctccaacg ttctccaatg gtctgggatc gcgacttgat gaagcagttc ggtcgtccga
    85021 tcgattgctt gtatgttttt ttctacgata gccattgatt tatgtccata gcttttcagg
    85081 gcttcttctt ttagcagcgg aagcacctca tcaaaaggaa tgatgtcagc taatttaaaa
    85141 aaagccgttt ccattgccgt attgatccgg cgtcccaaac cgacttcttg ggccaatctc
    85201 atggcattga tcgtatagaa tctaatgtta ttttcagcca agtaacgttt taattttaag
    85261 ggcagatgcg tttctaattg ttcgtcgctc caaagagtat tcaataaaaa aatgccacct
    85321 ggcttcaatc ctttgaccaa gtcatagcta tgcaggtaag ctggtgtgtg acaggcaaca
    85381 aggtccgcat gctcgacaag atacgctgaa cgtatcggcg tatctccaaa acgaagatga
    85441 gagacagtca gaccgccaga ttttttcgaa tcataataaa aatagccttg cgcatattta
    85501 tcggtgtgat ctccaataat cttgatagct gatttatttg ctccaactgt tccgtcagat
    85561 ccaaatcccc aaaacttggc ctggaatgtt tgcggttctg tcaaatccag actttccttt
    85621 ggttccaaag attgataagt cacatcatcc acgatcccta tggtaaaccg ttttttgcgt
    85681 atgcttgggt cttttttcaa ttcatcaaaa actgctgaga tttggtcggg agtcacatct
    85741 ttagacccca atccgtagcg accaccaata acagccgggc gaagttcaga atcatataac
    85801 gcactttgaa cgtctaataa gagaggttct ccacctgccc ctggttcttt acttcgatca
    85861 agaacagcaa ttgtttttac tgtatgaggc aacttttgca cgaatgtttc cactggaaaa
    85921 ggacgataaa gatggatatt caaaaaacct gttttccgtc cgtttgcatt caagtaatca
    85981 atcgtttgtt caatcgtctg tgcaactgat cccatagaaa caatgacttc ttccgcatcg
    86041 tctgctccgt aataagtcac caagtcataa gaagttcctc gtaatcggtt gatctctttc
    86101 atatattttt gaacgatttc aggtaattta tcataatagg ggttgatcgt ttcccgttgt
    86161 tgaaaatgga tgtctggatt ctggttcgta ccactaacag tcggatgatt gggattcatc
    86221 cctcgtttac gaaatgaagc taatttctcc tgattgatca gaggagctaa ttcttcatat
    86281 tccaaaactt cgattttttg aatctcgtga ctcgtacgga atccatcaaa gaaattcaaa
    86341 aaaggtactt ctccttcaat agaagcaaga tgggcaacag gtgctaaatc catcacttct
    86401 tgtacactgc tttcagctaa catagcaaat cctgtttgtc ttgcagccat cacgtctccg
    86461 tgatctccga aaatattcaa cgcatttgtc gtcactgccc gactagcaac atggaaaaca
    86521 cttggcagta gttccccagc aatcttgtac atattcggta tcatcaaaag cagcccttga
    86581 gaagcggtat atgtagttgt cagtgcacca gttttcaatg atccatggac cacaccagct
    86641 gctcctgctt cggattgcat ttctactact tttactggtt gaccgaatac attttctttt
    86701 cctgctgctg accattgatc tactaattca gccatggtcg aactgggtgt tattggatat
    86761 attgcagcaa tctcggtaaa tgcataagaa atatatgcgg ctgccgtatt gccatccatt
    86821 gttttcattt ttcgcatgat tcatcatcct tgttcatatt ctctcttatt atctgttcca
    86881 ttataacgta aaacattcca ttttttcttt tatttataaa aatatttcac atatgtctat
    86941 ttgaattggt catctaattt ttagacaaac agtctaaatc gttgcctttt tttgtcagac
    87001 atgtataaac tataagcgaa agaggtgttt taacatggat atatcagtga ttgatgcaac
    87061 gaaaacaaat acacaaaaag gaatccttta tggttcatcg aatgctccta aaaaaatggt
    87121 cgaattcatc aacctatctt gtccgtattg ccgacaatgg tttgaagaat cttatgagct
    87181 attagaagaa gcagtccaaa gcgggcaatt gcagcgagtg atcaaattgt tcgataaaga
    87241 aaaagaaagc ttgcagcgag gaaacgtgat gcaccggtat ctcacaatca gcgatggtca
    87301 aaaagcgatc aaagagatca aacaaatatt cgatactcaa gacgagtgga aacatctttc
    87361 tctccaagaa gtagcggatt ttgcagtaga taaactaaag ctgacagaac aaaaagacga
    87421 acagctgagc caagctgtca tcaacgaagc tgagcaagca catattcgat ttgttccgac
    87481 tgtcatcttg ggtaaagaaa tctttgatga atctatttca atagaggaat taaaagaatt
    87541 gatccaaaca aaataaaaaa ataaggagcg taggacaaaa gtaaagaaca cttttgtctc
    87601 acgctctaaa cacctataaa cggcggaagc agaagcaact ccttcttatt tcttggagtt
    87661 aaacgcttct gtcccagcct ccttattccg aataaatggt gtccaaaagc ttgcatctgc
    87721 cagattatct catttcttat gacaagctga gcaaattatc tccaccaaat aatttattca
    87781 tatttttgac ttgcgcatac taactaattc ttaaattttc atacaaaatt tctcaaattc
    87841 ccttaacgag taatatttat gtacggtgat tcacactagt atcccaatca ctttttaagt
    87901 tatcccgatt tcaattctac ttcaaaaata gttgctttta tgtatgctgt tagttgatta
    87961 gatggtcgtt tgttgagcta ggtcgtttat tttaaacaag ttgtttcttt agcttatacc
    88021 tatctcgtct accaaacgca agatggcaaa cacaaatgca tacgcatctg tatttgccac
    88081 tttgattcgt ataaagctaa caactcctaa ctcctctcat ttaatagttg ctctcttttt
    88141 tattcagata catttttgct gatcacagcc tagtatttca atggttttga acactaaacc
    88201 aaattgttcc attacaacat tcactggctg atgaaatgga ttaatagatt tcgattattc
    88261 aaagcgattt tctattggtg gattgtgttc ccaactaaca agacggattc caaagtcatt
    88321 atataactct tcaagagtta accctttcct gttcccaata gatgtatctc tcccacgctc
    88381 gatataaaat atggagtttc gaatgccaag acctggcaaa tctttccttg ttacagttac
    88441 actgctacta acttccccat ataaaatcca gctcctccaa aatgataata tatttttcga
    88501 ccatcatcta actcatgtaa caataattgt tgtgccctct tgtcactcgc caaatgcaaa
    88561 cgccacgtgc gataccatgc catgctacct gcatctgcag aaaatccatc aaataatgca
    88621 acaattgtat cttctatcac aatcctttcc ccatctactt catattctaa tctaaaatca
    88681 aactcccctc gggtaatcgc aggtcttggt ggcttaggac ccaatattat tctacttaaa
    88741 accgcattcg ttcccagatg aaacacagct ataacaacaa taatgattaa tattttgttt
    88801 ctatttgata aatttctcat tattcgcaaa tcacctctac attctcacat actagttcgt
    88861 aatactcctt taatatcaaa atatctactg atcgtaataa tattcgctat gaattcctac
    88921 tactcgtata agaaaggcca aatcatcagc ttttacttgc tgatgatttg gcttgtttct
    88981 atttatcgta attgttttct aatcaccaaa attgttaaca atcggttcag atatttccca
    89041 attcactagc cttatattat attgatttaa caattcttct tcatttattg tattttgatc
    89101 aagcggacca aattgttcta ataattcttt gtcatgtaaa atatcccttc tagtaatgcc
    89161 tctttccctt tcaatgaaag aagcactagg aaaagtatga ttataaccat tcaacctatc
    89221 tcccatgtaa taattagcag gtcctggaaa ataaaatatt tgcttattat cactaacttc
    89281 taacagcaac actaaatctt ctccgctggc taaacgactt gtccatctac gatatctccc
    89341 tatgccttcg ttcattccaa atccatcaaa ttcaactatt aacgtgtctt ctatcacatg
    89401 taattcttca ttcaattcat actcaagtct aaaaggaaat tctccatatg taatctctgg
    89461 caatggtggt gctggagttc tccaaataaa tacaataact gtgaatagaa aaaatccaac
    89521 gatcgatata aatgttatga gacctgctcg aagtaaaacc cgatataata aaaatgctgt
    89581 atttcgcttt gctatatcta gaaaaataaa aagtactgca atcataatga tagtaaaagt
    89641 tgtaaaaaaa cgcatttttg ccctcccttt ataaacatcg attctcaaat tctaaaccaa
    89701 atcttggtag ttcaagttca ggtataacgt attccaacca tacatctcaa ttactattta
    89761 tgaacttatg attatcactg aataaatcac tccatcccct tgttaaaact tctacattaa
    89821 ttacacctgg ttgttttcga ctagctaatc caatgaactt atcaaccatc cttatccacc
    89881 aaccacgaga atcttgacca gaagtaagaa gagcagttct caaggatgat cgagcagttc
    89941 cttccagttt tttaattaat caggccagtt atagataaat acttgatctt atctatatca
    90001 ggacttctat attaagcaaa aatttatgta caaaactaaa atcttcattc agttgtctcc
    90061 ccgcttttta tacgattgta ttaaaaacaa tagaagcctt tccaaattat gttactccag
    90121 taaagatgga attatagttt gacggaagaa aagcaagtat aacttttaaa aaaaactgat
    90181 acattcgcat ctcctgcttc atgtatcagt tttttctttg gattaaactg cttcttcacg
    90241 cagtttttcc gcaaattcat ttattttgcg aattcggtga ttaattcccg attttgatat
    90301 cgcacctgag ggaatcattt cccctaattc tttcaagctg acctctggat gttgaagccg
    90361 aagttctgcg atttcctgaa gtttttcagg aagggcatgt agaccgacct ttgcttcgat
    90421 caattcgatg ttttcgattt gtttagaagc cgcatcaatc gtcttgttca gatttgctgt
    90481 ctcacaattg actagacgat tgaccgaatt tctcatatcc cgtacgattc gaacatcttc
    90541 aaatcggagc attgagttgg ttgcaccaat caatgttaag aaatcagcaa ttttttctgc
    90601 tccttttaaa taagaaatat agccattgcg ccgttcaagc gttcgagcat gtagaccgta
    90661 ataatttaac atatcgcaaa tgtcttggtt atgctgttca taaatagaaa atatttccaa
    90721 atgataacgg ctcgtttccg gattattgac tgaacctgag gccataaaag caccacgtaa
    90781 gtaagaacgc attttttgcg aatttcccat aatctcgtcc gaaacgtgtc cattgaacat
    90841 cataccatcc atgatatcaa gatccatcaa cacatctttt gtgccttgct tcaaccggac
    90901 gatatagaca ttgttctttt ttaatttcat ttttttacga acgagtagct cacttcgtac
    90961 ctgataatga tctttcaaaa gagaatagat acgtctggca attgcagcat tttctgtttg
    91021 gacgttcaaa ataaactgct ggttcacaat acctaaagag ccgttcattc gcagcaaagc
    91081 agctaattcc gctttcgcat gttctcgatg aacttccaaa ccagttagtt ctttcttcac
    91141 atctgcagca aatgacatcc tattctcctc ctttctccaa caataaattg cttaatattt
    91201 tgaaccgaaa actaaacgga acaattcttc tactactttg tctccatcgt ggaagacacc
    91261 accatctttc aattccaaaa agtcggtgga aatcactcga catccttcat ttctcaatcc
    91321 gttgaagtcg tgtgcgactt gtactagata ctcatcatag atctctgggt ccatataatc
    91381 ttcaggcact ttttccgtat tgaccaatac tgtatcgata aaaggctgat tcaaatgctt
    91441 gtgtaaaaca cgtatatgat cggcatctgt gaaatgttcc gtttcccctt tttgggtcat
    91501 gatattacag atatagacgg tttcagcagt tgtcttgagc attgcttcgc cgatttctgg
    91561 tatcactaaa tttggaagga tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc
    91621 ggcgtccata attgctgaaa cgacttttcg agccgctttg gcttcacttt tatcatttgt
    91681 gttgcagaca tacacacggt caatggtttt acggtcgatc gcgattttag attctcctac
    91741 tgcagtcgtt ccgtctttaa agacagcatg caaggtcaaa ggagtttctg aagaaggata
    91801 aacatgtcca tctacatgca tcatttttgc taataattga atcgcctcat aagtgcttcc
    91861 ccgcatctcg gaaactgcgg caatgatcag attaccgatc gtatgattgg ctaaaaactg
    91921 atcttccttt ttgaaacggt attggaaaat atcttcatag aattgtggca tatccgataa
    91981 cgccactaag acatttctca agtcaccagg aggagccata gcgatcgatt ctctgattgc
    92041 accgctgctt cccccatcat ctgcaacagt cactactgct gtgatatctg ctccttgatt
    92101 tcgcaaactt ttcaggataa ctggcagacc agtgccaccg ccgaccacta cgatctttgg
    92161 ttttcttatc cggtaggttt tcattttcac gaccggttca ccgtctcttt ccttttatcc
    92221 ttgtcccgat gtgtcacatt gactttatag tttttcccta aagcatttgc caaacgttca
    92281 gtcaatgcca cagaacggtg ttgaccgcct gtacagccga ttgcaactgt caagctgctt
    92341 tttccttctt taatgtatcc aggcaataca gtttccagaa gatccaaaaa tttatggtag
    92401 aatgattgcg tttcatcaaa ggacatcaca taatcataga ctggctgatc ttttccggtc
    92461 aatggtctta gttccgggat ataatgaggg ttgggcaaaa aacgcacatc catcacaata
    92521 tccgaatcga tcggcaaccc gtatttaaaa ccaaatgata caaattcgat ccgaaatcct
    92581 tggtctccct ttgatttgaa tgactcattg attttttcac gtaattgtcg tggtgtcaat
    92641 gtcgtcgtat caatgatcac ggaagcttgg gctttcaagt cgtctagtat cgcccgttct
    92701 ttacgtatcc cttcagtgat caaaccgtcc atcgccattg gatgtgctcg tcttgtttct
    92761 ttgtagcgag ccactagttc ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg
    92821 aagttcgtat tttcgatttc gatcagcatg ttttggattt cttcaaagaa ggaacgagaa
    92881 cgtaaatcca ctcctaaagc catttttgtg actttgcctg attctttgat taattcccag
    92941 aattttggaa tcaatcgagg cggcatatta tcgatacaaa aatagcccat atcttcaaaa
    93001 ctttggatag ctactgtttt ccctgcaccg ctcatacctg ttatgatgac taattgcaaa
    93061 ttatctgtca taattacgaa ctcctctcac attgtgcata gtaaaattat atcattccgg
    93121 gcgtatcatt accagttttc tttttctttt acaaaaagat ttggaccaaa tatcttttag
    93181 gatatttgcc ccaaatccaa tttttttact tttccgatgc tgtatccaat gccttgcttc
    93241 tttcagctag cgctcgttca atcgtccgat ctgctaaaat agattgggca tcgatcactg
    93301 gataatggtt atcttcagca aattcatgca tcaatgacaa ttctgtgcaa cctaagataa
    93361 ctttttcaca gtttaggcgc tctaccgctt cttctaagat ttcgtaatat agctcttgat
    93421 tcaaataatc cgattccttg atctcatgat agatcagata attgattttt tcttgaagaa
    93481 cagtatcagg aatcactgtt tcgaatccaa gatttttgac ttcgcgttca tagattccag
    93541 ctttcatact tccttctgtt cctagaatcg ctactctccc tgtcgtatgc tgacggacaa
    93601 gttcatttgc tgcttctctt ggcatatgaa ggataggaat atccgttgcc gcttgtaatt
    93661 cttcaaaaaa gtagtgtgcg gtgttacaag tcaacacaat gaagttcggc tgcaataaat
    93721 tttgtttctc aatatcatcc agcagaaacg gcattggatt ttcttctgat cgatctaaaa
    93781 tataagctgt acgatcagga actgttgcat gattgaataa gacataattc aaatattctt
    93841 gatcttttgt agctttcgtt cggtggttga tcaagcgaac aaaactttct gtcgccatcg
    93901 tgcccattcc gcctaaaata ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa
    93961 aatacttttt gaatcttgga atatagttat ggaacatata tttcatcaac aaccagcgct
    94021 tgattgaccg gtctttttca taaaacacag tagtaccgta acgattttct ttgatcattt
    94081 gctcagctag ttttttgtct tcattttccc gagcatattc taaaaagatt tttttgggca
    94141 cacccatcca taatcttgct ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg
    94201 gtttgttaaa cactcgatct tctgtgacga aacgagccag attcaagccg ttcaatgtca
    94261 caaagaaact gctacgacct tgtctcaaat tgatttcaaa taatttatat tctccatctc
    94321 taggatcata cttcatatcg aaattggcaa agcctgtata ttcgattttt tccaaaaatg
    94381 ccttaatggt ttgatagatt ttttcgttat aatctggcat gatcacaacg taattaccaa
    94441 tcgatgctgg tgtaggatct tctaacagtg gatgaccaag acacatcatc cgaacttgat
    94501 gatcttcatc tacatacgca tttagcacac gcatattact atcatcaccc gggataaaat
    94561 cttgtacaat catttcactt ttataaccgg cttcgtatat ccggcctaaa attaaatcga
    94621 actcttctct agtctctaaa ataaaagctt tttttcttcc ttcaaattgg acagaaagat
    94681 actccacact gtttgcaggt ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca
    94741 aatgtccatt tactaacatt tcttctctga cgatcaatgt tttaggatac ggaagatcat
    94801 attcttcaca aacttcataa aagcttactt tattgatcag tctttcaaat aaagaataat
    94861 caatatatgg acagataaaa tattctgaca gctcttgttt atgttgggag atcaattctg
    94921 catatccatc accacaagca atcaaaagat attttttact cttatcagaa tatctttctt
    94981 ttgccaaacg aagcatcgtc tcgataaaca cagggtcttt atcaaatcct ggaataactt
    95041 ctacattgac aattttactg tagcgggtag gggctaactg atccgaagca tatgcttggc
    95101 agattttgcc gtatgcttca ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc
    95161 ctaataatat agggataaat tcttcatttt caatactgtt catcattatc tctcacttac
    95221 tcataatctc ttgtttttct tttccaacta cacaaggaat atcataccat aaagaaaaaa
    95281 gcaatcaaag gaaactcctc cgattgctca attctttttt gaacggattg aacttatagg
    95341 aagtttttgt ctataccaat cagtgtagaa agaactacca tgtaatgatt ctagaacact
    95401 gatattaata aaacaagcaa aaattcattt ttttatgttt ttttaactat ctcagctatc
    95461 tatcctcttt ataccattat ttttttcaaa tagtgacctg tataactttc ttttacgtta
    95521 atgatttctt ctggtgttcc agtcgcaagg atcgttcctc caccttctcc accttctggt
    95581 cctaaatcaa tgatataatc tgctgttttg attacatcta gattgtgttc aatcactaaa
    95641 actgtgttac cagcatctac taatctttgt aatacatgca acaagcgggc gatgtcatcg
    95701 ctatgaagtc ctgtcgttgg ttcatctagt atatagaaat tctttccatt agagattttg
    95761 tgcaattcac tggcaagttt catccgttgt gcctcaccac cggacaatgt cgttgctggt
    95821 tgccccatcg tcacataacc taagccaaca tcaacaatcg tttgcagttt gcgatgaatc
    95881 tttggaatgt gcttgaagaa ttctacagca tcttctactg tcatttccaa aatatcagca
    95941 atgctttttc ctttgtaatg cacttctaat gtttcagagt tatatcgttt gccatgacat
    96001 acttcacaag gaacatagac atcaggcaaa aagtgcattt cgatcttaat aattccatcc
    96061 ccgcgacaag cttcacaacg accgcctttt acgttgaaac taaaacgccc tttcttataa
    96121 ccccgcattt ttgcctcgtt cgtttgagca aataacccac ggatatcatc aaatacactt
    96181 gtataagtcg ctggattact tctcggcgtc cggccgattg ggctttgatc gatatcgatg
    96241 atcttttcga tactttcgta gccggaaatt gtcttgaatt tacctggctt agcagaattc
    96301 ttatttaatt tttgcgctaa cgatttcttt aagatactat tgaccaatgt actctttcca
    96361 gaaccagaca cacctgtgac tgctacaaat tctcctaatg gaaattcaac actaatattt
    96421 ttcagattgt tttctgaagc accagtgatc ttgattgctt tcccattacc tttacggcgt
    96481 tcttttggta cagggattga ttttttccct gaaagatatt tccctgtcaa agaattttca
    96541 tcattagcta cttcttcagg agtgcctgca gccacgattt gtccgccttg ttctccggcc
    96601 ccaggtccga cgtcaatcag ataatctgct gcccacatcg tatcttcatc atgttcgact
    96661 acaacgaggg tgttgccaag atcacgcatt ttctttaatg agccaatcag tcgatcgttg
    96721 tcgcgttgat gcaatccgat cgatggttca tctaaaatat acaaaactcc agaaagattc
    96781 gatccaattt gtgtagccaa tctgattcgc tgcgcttctc ccccagataa tgttccggaa
    96841 gcgcgactca aagttagata gtctagtccc acattttcca agaatgaaag tctgtcattt
    96901 acttctttta aaatcggttt ggcaattact ttctcttgtt cagataacgt taagtttgag
    96961 aagaaatcta ctgctttttg aatagacaac tcatttgttt gcccgatatt cgttccattg
    97021 atttgaacag atagagcttg gggattcaat cgataacctt tacatgtctg acaagttaat
    97081 tctgtcatat aaagacgcat ttgctcacgc gtgaaatcac tgttcgtatc atgataacga
    97141 cgctcgatat tcttcaatac cccttcgaaa gtcgtttcta catcgcgaac gccaccaaaa
    97201 tcattttcat aatggaaatg gaaaagatca tctgtcccat tcaagatgat atcctgatgc
    97261 tcttccggta attcttcgaa tggtgtatct aaatcgatac cgaaactttc acaagcctgc
    97321 gctaacattt gaggataata ctgagagctg attggattcc atggaacgat agcaccttga
    97381 ctaagtgtct tcgttctatc tggaatcact aaatcttgat cgacttctaa tttgacacct
    97441 aaaccatcac agtctggaca agctccaaaa ggcgcattga atgagaacag tcttggttct
    97501 agttcgccaa cagtaaatcc gcaataagga caggcatagt gttcgctaaa caacatttct
    97561 tcttcaccga tcacgtcaac cagagcatag ccgtctgcca atcgcagagc cgcctctaaa
    97621 gaatcaaata gacgagaacg aatcccttct ttcacaatga tccggtcgat gacgatcgcg
    97681 atatcatgtt ttttgttttt ctccagctca ggcacttcac ttaaatcata gatctcacca
    97741 tcgactcgaa cgcggacgta tccctctttt tggattcgtt cgaatatttt tttatgttgt
    97801 ccttttttct ttaccacgat cggtgccaac acttggatct ttgtgcgctc aggcaaagcc
    97861 attacttgat ctgccatttg atctactgat tgactggtaa tctcgatatg atcgttggga
    97921 caaatcggat gtcctacacg tgcaaacaac aagcgtaaat agtcattgat ttccgtcaca
    97981 gtacctactg tcgaccgagg atttttactt gttgttttct gatcaataga aatcgccgga
    98041 ctcaatccgt cgatgctatc tacgtccggc ttatccattt gtcctaaaaa ctgacgagca
    98101 taagcagaaa ggctctctac gtatctccgc tgcccttcag cgtacagcgt atcaaatgct
    98161 agggaacttt ttccagaacc ggacaaacct gtaacgacca cgaatttatc tcgtggaatc
    98221 gttacatcta tatttttcaa gttatgggca cgtgcaccgt gaatcgtaat tttatcgtta
    98281 gccatgttgt cctcctactt tgaagctttt aattctaaaa tcatatctcg cacattagcg
    98341 gctgtttcaa aatccaatgc tttcgccgca tttttcattt ctttttctaa tttcatcaat
    98401 aacgtatctt tttcttcttt cgtcatttct tcatacgaga cttgtaccgc ttcttttgta
    98461 tcatcttccg attctttcgt aatagaaatc aaatctcgga tttctttaat gatcgttttt
    98521 ggaacgatcc catgttcttc attgtacttc tgctgaatcg tacggcgtct tgatgtttca
    98581 tccatcgcta gacgcataga atctgttact ttgtctgcgt acatgattac tttaccttct
    98641 tcattccgag cagctcgtcc aatcgtttgg actaaggaac gttcactacg taaaaagcct
    98701 tctttatccg catccaagat agcaacaagg gaaacttcag gtacgtctaa tccttcacga
    98761 agcaaattga ttccaactaa cacatcaaat tcacctaatc gaagatctcg aatgatttct
    98821 gttcgttcca gcgttttgat atcactatgc aaatatttga ctttgatccc taattctttg
    98881 aaataatctg tgaggtcttc tgccattttt ttcgtcaatg tcgttacaaa cacccgctgg
    98941 tctttttcga ctcgttcatt tatttcgcct actagatcat cgatttgtcc catgattgga
    99001 cgaacttcga tcactgggtc aagcagccct gtcggacgga tgatttgttg gataacggta
    99061 tctgtttgtt catgttcata tggtcctggc gtcgcagaga cataaatgat ctgattgaca
    99121 tgtttttcaa actcttctaa ccgaagtggc cgattgtcta aagcagatgg caaacggaaa
    99181 ccgtaatcta ctagcatctg ttttctcgct cggtcaccat tatacattcc tctgacttga
    99241 ggcatggtta cgtgcgattc gtccgccacg atcaaaaaat cttcaggaaa gaaatccaat
    99301 agcgtataag gcggttcacc ttctttacgt ccgtccatat gccgagaata attttcaatt
    99361 cccgacgtgt agcccatttc taacatcatt tcaatatcgt aattggttcg ctgttctaaa
    99421 cgttgagctt ccagaagttt gttttcattt cgcaagacag ttaaacgctg ttctaattcc
    99481 gctttgatat tcgctacggc atgctccata tgttcatcat tcgtcacaaa gtgagtcgcc
    99541 gggaagattg ccacgtgttc cgtttctcct aaaacttcac ctgtcagtgc attgacttct
    99601 cggatacgtt cgacctcatc tccaaaaaac tccacacgta aggcacgttc atctcttgaa
    99661 gccggaaaaa tctccacgac atcaccgcgc actcgaaaac gaccgcgctg aaaatctata
    99721 tcatttcttt cgaattggat actgactaag tcacgaatca actgattgcg atctagttct
    99781 gctccctgtc gaatcgaaac tacttgtttt tggtactcaa aaggcgaacc taatccaaaa
    99841 atacatgaaa cggatgcaat gacgatcaca tcatttcttt ctaataatga actagtagcc
    99901 gaatgtcgta atttgtcgat ctcatcattt acacttgaat ctttttcgat atacgtatcg
    99961 cttgaaggca cataagcttc aggctgataa taatcataat aagaaacaaa atattcaaca
   100021 gcattgttag ggaaaaattc cttgaattcc ccgtacagct gaccagccaa tgttttgtta
   100081 tgggcaataa ttagtgttgg tttattcact ttctcaataa gattggaaat cgtatatgtt
   100141 ttccctgttc cagtcgcacc taataagatt tgtgcttttt tcccgccgac tacgccatcc
   100201 actaattggt taatcgcttc aggctgatca ccagccggtt ggtatttcga gacaagctca
   100261 aagtgtcggg aggtatctct ctcaatcatt cttcgtcctc cttttcattc attccttttc
   100321 attttacgac caataaaaag aaaaggaaag caaaggcatt ccttactaaa aaattatacc
   100381 acaccgaaca tactttcgcc acttttttat cttattatgc atgttacgtt ttataacata
   100441 aaatgttaga aactcgcatt tttttcattt tttcgagctt acagtcttgt ctgattcagc
   100501 acttttcgcc tataataata aaatattgga aatttaggag gttgattatg aaaagaaagc
   100561 atttatttca ctcatttgtt ttcttaatga caggacttgt gacacttgcg tttggacatg
   100621 ttgcacaagc tgacaacact acaacggcag agtcaagcac aagcgagaca atgcaaaaaa
   100681 tagagcccaa aaaagacgta tacgtaattg ccagtgactc tgcttttgct ccatttgaat
   100741 ttcaaaacgc aaagggcgag tacgaaggca tcgatgtaaa attgatggaa aacatcgcca
   100801 aactgcaagg atttaacatc cgaatggact accgtggttt ctctgctgct ttgcaagctt
   100861 tggaatcagg acaagcagac ggaatgattg ccggaatgac tgtaacagat gaacgaaaga
   100921 aaagctatga tttttctgat tcttactttg atagcgggat ccaattagct gtcaaaaaag
   100981 gagatacttc gatcaagtct tatgaagatt tgaaaggaaa aacagtcgga gcaaaagttg
   101041 gtaccgaaag tgctgaattt ttaagcgacc atgaatctga atatggctat tctatcaaat
   101101 attttgatgc tgctgatcaa ttgtacgacg ggttaaaagt tggcgcaatc gatgcaatga
   101161 tggatgatta tccggtaatc ggttatgcga tcaaacaagg acaagaattg gaaacaccga
   101221 tcaaaaaaga atctggcgga aaatatgcat ttgccgttaa aaaaggacaa aatcctgagc
   101281 ttcttaatat gttcaatgaa ggattgaaag aattaaaaag aacaggcgaa tacgataaga
   101341 ttattaaaga atatgtagcg gatggttcag aaacttccag tgagtcttcc actgctgatg
   101401 aatcaacatt tcttggactt atccaaaaca actatcaagc attgttgaaa ggactttgga
   101461 gaacaattct cctaactttg atctcctttg ctttggctat agtaatcggt gtgatttttg
   101521 gattattcag tgtagcacca atacgcgctc ttcgcacaat tgctagtatt tatgtcgata
   101581 tcatccgagg aattccaatg atggttcttg cgttctttat tttctttggg ttgcctggta
   101641 tcgttggatt tacgattcct gacttccttg ctggtgttat caccttgact cttaacgcaa
   101701 gtgcttatat cgcagagatt gttcgaggcg ggatcaacgc cgttcctgtc ggacaaatgg
   101761 aagcttccag aagtttaggt ctttcttata atcggacaat gcaaaaaatc attttgccgc
   101821 aagcgatacg catcatgatc ccatcattcg tcaatcagtt cgttatctca ttaaaagaca
   101881 caacgatcat ttccgcaatc ggtgtagtcg aattgctgca aactggtaag atcattgttg
   101941 cacgtacaac acaaagtacg tatgtttact tgatcattgc gatcatgtac ttgattttga
   102001 tcacagcatt gacaaaatta gcaaaagttt tagaaaagaa ggtgaagtaa gatggcagaa
   102061 aaaatcttag ttgagcattt agtcaaaaaa tacggcgata acacagtatt aaacgacatc
   102121 aatgtgtcca tcaacgaagg agatgtcgtc tgtatcattg gcccttcagg ttcaggaaaa
   102181 agtacatttt tgcgttgctt gaatcgttta gaagaacctt ctgacggtga aattattatt
   102241 gacggcgccc acttgatgga taaaagcaca gatatcaact tggtgagaca acatatcgga
   102301 atggtattcc agcactttaa cctattccct catctttcta ttttggaaaa catcatttta
   102361 gcaccgatgg acctgaagaa agaatctaga gaagaagcag agaaaaaagc aatcaaattg
   102421 ctgcagacag ttggtctaga agataaaaaa gatatgtatc ctgaaatgct ttccggtgga
   102481 caaaagcagc gtgtggctat tgctcgtgct ctagcgatga accctgacat catgcttttt
   102541 gatgagccta catctgcact cgaccccgaa atggtcggtg atgtcttgaa cgtcatgaaa
   102601 aagttagcag aacaaggtat gacgatggtt atcgttacgc acgaaatggg cttcgctaaa
   102661 gaagtggcca atcgtgtcat gttcattgac gacggaaact ttttagaaga cggaacgcct
   102721 caacaaatct ttgaaaatcc gcaaaatgaa cggacaaaag atttcttgaa taaagtatta
   102781 aatatttaat aaaaaccaaa aatgcccggt cgcttcatga cgaccgggca tttttagttt
   102841 cttgtttttt cacttaactg taccagccgc atcgcttgtt ctcctgcaca aacaagcaat
   102901 cgctctacct gttccatcgc ataagaaagt accatcggtt cattgacgat atcaagtaca
   102961 tagtcgatac caccttcaga aactatgatg attatcttat tctaaagctg gcttttttgt
   103021 tggtacaaac atgacaacta caaaaaa
//
LOCUS       DAZAOD010000002        82596 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000002 DAZAOD010000000
VERSION     DAZAOD010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 82596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.002"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            17..1648
                     /locus_tag="ACHDPO_000095"
     CDS             17..1648
                     /locus_tag="ACHDPO_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFN3367764.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(1710..2351)
                     /locus_tag="ACHDPO_000096"
     CDS             complement(1710..2351)
                     /locus_tag="ACHDPO_000096"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFN3367765.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    2537..2613
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            2633..2941
                     /gene="rplU"
                     /locus_tag="ACHDPO_000097"
     CDS             2633..2941
                     /gene="rplU"
                     /locus_tag="ACHDPO_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFN3367766.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            2968..3312
                     /locus_tag="ACHDPO_000098"
     CDS             2968..3312
                     /locus_tag="ACHDPO_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFN3367767.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            3325..3618
                     /gene="rpmA"
                     /locus_tag="ACHDPO_000099"
     CDS             3325..3618
                     /gene="rpmA"
                     /locus_tag="ACHDPO_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFN3367768.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            4052..6859
                     /locus_tag="ACHDPO_000100"
     CDS             4052..6859
                     /locus_tag="ACHDPO_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFN3367769.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            7050..7541
                     /locus_tag="ACHDPO_000101"
     CDS             7050..7541
                     /locus_tag="ACHDPO_000101"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFN3367770.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            7644..8633
                     /locus_tag="ACHDPO_000102"
     CDS             7644..8633
                     /locus_tag="ACHDPO_000102"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFN3367771.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            8666..9469
                     /locus_tag="ACHDPO_000103"
     CDS             8666..9469
                     /locus_tag="ACHDPO_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFN3367772.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            9490..10404
                     /locus_tag="ACHDPO_000104"
     CDS             9490..10404
                     /locus_tag="ACHDPO_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFN3367773.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            10487..10861
                     /locus_tag="ACHDPO_000105"
     CDS             10487..10861
                     /locus_tag="ACHDPO_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFN3367774.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            11000..11245
                     /locus_tag="ACHDPO_000106"
     CDS             11000..11245
                     /locus_tag="ACHDPO_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFN3367775.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            11417..12481
                     /locus_tag="ACHDPO_000107"
     CDS             11417..12481
                     /locus_tag="ACHDPO_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFN3367776.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            12727..13152
                     /locus_tag="ACHDPO_000108"
     CDS             12727..13152
                     /locus_tag="ACHDPO_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFN3367777.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            13145..13594
                     /gene="nusB"
                     /locus_tag="ACHDPO_000109"
     CDS             13145..13594
                     /gene="nusB"
                     /locus_tag="ACHDPO_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFN3367778.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            13691..14545
                     /locus_tag="ACHDPO_000110"
     CDS             13691..14545
                     /locus_tag="ACHDPO_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFN3367779.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            14546..15883
                     /gene="xseA"
                     /locus_tag="ACHDPO_000111"
     CDS             14546..15883
                     /gene="xseA"
                     /locus_tag="ACHDPO_000111"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFN3367780.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            15888..16112
                     /locus_tag="ACHDPO_000112"
     CDS             15888..16112
                     /locus_tag="ACHDPO_000112"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFN3367781.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            16114..17004
                     /locus_tag="ACHDPO_000113"
     CDS             16114..17004
                     /locus_tag="ACHDPO_000113"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFN3367782.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            17013..17831
                     /locus_tag="ACHDPO_000114"
     CDS             17013..17831
                     /locus_tag="ACHDPO_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFN3367783.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            17938..18387
                     /locus_tag="ACHDPO_000115"
     CDS             17938..18387
                     /locus_tag="ACHDPO_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFN3367784.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            18405..20087
                     /gene="recN"
                     /locus_tag="ACHDPO_000116"
     CDS             18405..20087
                     /gene="recN"
                     /locus_tag="ACHDPO_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFN3367785.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(20142..20258)
                     /locus_tag="ACHDPO_000117"
     CDS             complement(20142..20258)
                     /locus_tag="ACHDPO_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFN3367786.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(20331..21287)
                     /locus_tag="ACHDPO_000118"
     CDS             complement(20331..21287)
                     /locus_tag="ACHDPO_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFN3367787.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            21458..21826
                     /locus_tag="ACHDPO_000119"
     CDS             21458..21826
                     /locus_tag="ACHDPO_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFN3367788.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            21996..22427
                     /gene="mraZ"
                     /locus_tag="ACHDPO_000120"
     CDS             21996..22427
                     /gene="mraZ"
                     /locus_tag="ACHDPO_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFN3367789.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            22448..23407
                     /gene="rsmH"
                     /locus_tag="ACHDPO_000121"
     CDS             22448..23407
                     /gene="rsmH"
                     /locus_tag="ACHDPO_000121"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFN3367790.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            23412..23813
                     /gene="ftsL"
                     /locus_tag="ACHDPO_000122"
     CDS             23412..23813
                     /gene="ftsL"
                     /locus_tag="ACHDPO_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFN3367791.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            23814..26006
                     /locus_tag="ACHDPO_000123"
     CDS             23814..26006
                     /locus_tag="ACHDPO_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFN3367792.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            26032..26994
                     /gene="mraY"
                     /locus_tag="ACHDPO_000124"
     CDS             26032..26994
                     /gene="mraY"
                     /locus_tag="ACHDPO_000124"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFN3367793.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            27008..28369
                     /gene="murD"
                     /locus_tag="ACHDPO_000125"
     CDS             27008..28369
                     /gene="murD"
                     /locus_tag="ACHDPO_000125"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFN3367794.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            28395..29483
                     /gene="murG"
                     /locus_tag="ACHDPO_000126"
     CDS             28395..29483
                     /gene="murG"
                     /locus_tag="ACHDPO_000126"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFN3367795.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            29498..30718
                     /locus_tag="ACHDPO_000127"
     CDS             29498..30718
                     /locus_tag="ACHDPO_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFN3367796.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            30874..32199
                     /gene="ftsA"
                     /locus_tag="ACHDPO_000128"
     CDS             30874..32199
                     /gene="ftsA"
                     /locus_tag="ACHDPO_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFN3367797.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            32222..33463
                     /gene="ftsZ"
                     /locus_tag="ACHDPO_000129"
     CDS             32222..33463
                     /gene="ftsZ"
                     /locus_tag="ACHDPO_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFN3367798.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            33480..34157
                     /locus_tag="ACHDPO_000130"
     CDS             33480..34157
                     /locus_tag="ACHDPO_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFN3367799.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            34171..34770
                     /locus_tag="ACHDPO_000131"
     CDS             34171..34770
                     /locus_tag="ACHDPO_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFN3367800.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            34851..35072
                     /locus_tag="ACHDPO_000132"
     CDS             34851..35072
                     /locus_tag="ACHDPO_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFN3367801.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            35121..35903
                     /locus_tag="ACHDPO_000133"
     CDS             35121..35903
                     /locus_tag="ACHDPO_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFN3367802.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            35924..36631
                     /locus_tag="ACHDPO_000134"
     CDS             35924..36631
                     /locus_tag="ACHDPO_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFN3367803.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            36893..39691
                     /gene="ileS"
                     /locus_tag="ACHDPO_000135"
     CDS             36893..39691
                     /gene="ileS"
                     /locus_tag="ACHDPO_000135"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFN3367804.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(39740..41266)
                     /gene="zwf"
                     /locus_tag="ACHDPO_000136"
     CDS             complement(39740..41266)
                     /gene="zwf"
                     /locus_tag="ACHDPO_000136"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFN3367805.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(41281..41928)
                     /locus_tag="ACHDPO_000137"
     CDS             complement(41281..41928)
                     /locus_tag="ACHDPO_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFN3367806.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(42112..42441)
                     /locus_tag="ACHDPO_000138"
     CDS             complement(42112..42441)
                     /locus_tag="ACHDPO_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFN3367807.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            42618..43346
                     /gene="sfsA"
                     /locus_tag="ACHDPO_000139"
     CDS             42618..43346
                     /gene="sfsA"
                     /locus_tag="ACHDPO_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFN3367808.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            43362..44375
                     /locus_tag="ACHDPO_000140"
     CDS             43362..44375
                     /locus_tag="ACHDPO_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFN3367809.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            44375..45652
                     /locus_tag="ACHDPO_000141"
     CDS             44375..45652
                     /locus_tag="ACHDPO_000141"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFN3367810.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            45715..48417
                     /locus_tag="ACHDPO_000142"
     CDS             45715..48417
                     /locus_tag="ACHDPO_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFN3367811.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            48569..48886
                     /locus_tag="ACHDPO_000143"
     CDS             48569..48886
                     /locus_tag="ACHDPO_000143"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3367812.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            48916..49236
                     /locus_tag="ACHDPO_000144"
     CDS             48916..49236
                     /locus_tag="ACHDPO_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFN3367813.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            49344..50804
                     /locus_tag="ACHDPO_000145"
     CDS             49344..50804
                     /locus_tag="ACHDPO_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFN3367814.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            50872..51093
                     /locus_tag="ACHDPO_000146"
     CDS             50872..51093
                     /locus_tag="ACHDPO_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367815.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            51124..51306
                     /locus_tag="ACHDPO_000147"
     CDS             51124..51306
                     /locus_tag="ACHDPO_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFN3367816.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            51306..51719
                     /locus_tag="ACHDPO_000148"
     CDS             51306..51719
                     /locus_tag="ACHDPO_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFN3367817.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            51842..53023
                     /locus_tag="ACHDPO_000149"
     CDS             51842..53023
                     /locus_tag="ACHDPO_000149"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3367818.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(53094..53258)
                     /locus_tag="ACHDPO_000150"
     CDS             complement(53094..53258)
                     /locus_tag="ACHDPO_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367819.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            53412..53485
                     /locus_tag="ACHDPO_000151"
     tRNA            53412..53485
                     /locus_tag="ACHDPO_000151"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:53446..53448,aa:Arg,seq:cct)
     gene            complement(53554..54693)
                     /locus_tag="ACHDPO_000152"
     CDS             complement(53554..54693)
                     /locus_tag="ACHDPO_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3367820.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            54865..54999
                     /locus_tag="ACHDPO_000153"
     CDS             54865..54999
                     /locus_tag="ACHDPO_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367821.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(54992..55627)
                     /locus_tag="ACHDPO_000154"
     CDS             complement(54992..55627)
                     /locus_tag="ACHDPO_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367822.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(55740..56375)
                     /locus_tag="ACHDPO_000155"
     CDS             complement(55740..56375)
                     /locus_tag="ACHDPO_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFN3367823.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(56409..56870)
                     /locus_tag="ACHDPO_000156"
     CDS             complement(56409..56870)
                     /locus_tag="ACHDPO_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFN3367824.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(57000..57431)
                     /locus_tag="ACHDPO_000157"
     CDS             complement(57000..57431)
                     /locus_tag="ACHDPO_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFN3367825.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(57449..57769)
                     /locus_tag="ACHDPO_000158"
     CDS             complement(57449..57769)
                     /locus_tag="ACHDPO_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3367826.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            58068..58844
                     /locus_tag="ACHDPO_000159"
     CDS             58068..58844
                     /locus_tag="ACHDPO_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFN3367827.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            58859..59062
                     /locus_tag="ACHDPO_000160"
     CDS             58859..59062
                     /locus_tag="ACHDPO_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3367828.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            59078..59416
                     /locus_tag="ACHDPO_000161"
     CDS             59078..59416
                     /locus_tag="ACHDPO_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFN3367829.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            59403..59582
                     /locus_tag="ACHDPO_000162"
     CDS             59403..59582
                     /locus_tag="ACHDPO_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367830.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(59625..60095)
                     /locus_tag="ACHDPO_000163"
     CDS             complement(59625..60095)
                     /locus_tag="ACHDPO_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367831.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            60182..60880
                     /locus_tag="ACHDPO_000164"
     CDS             60182..60880
                     /locus_tag="ACHDPO_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFN3367832.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            61058..61399
                     /locus_tag="ACHDPO_000165"
     CDS             61058..61399
                     /locus_tag="ACHDPO_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367833.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            61392..62063
                     /locus_tag="ACHDPO_000166"
     CDS             61392..62063
                     /locus_tag="ACHDPO_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFN3367834.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            62069..62761
                     /locus_tag="ACHDPO_000167"
     CDS             62069..62761
                     /locus_tag="ACHDPO_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFN3367835.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            62758..63507
                     /locus_tag="ACHDPO_000168"
     CDS             62758..63507
                     /locus_tag="ACHDPO_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3367836.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            63519..63788
                     /locus_tag="ACHDPO_000169"
     CDS             63519..63788
                     /locus_tag="ACHDPO_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367837.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            63794..63958
                     /locus_tag="ACHDPO_000170"
     CDS             63794..63958
                     /locus_tag="ACHDPO_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367838.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            63951..64250
                     /locus_tag="ACHDPO_000171"
     CDS             63951..64250
                     /locus_tag="ACHDPO_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367839.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            64250..64552
                     /locus_tag="ACHDPO_000172"
     CDS             64250..64552
                     /locus_tag="ACHDPO_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFN3367840.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            64592..64957
                     /locus_tag="ACHDPO_000173"
     CDS             64592..64957
                     /locus_tag="ACHDPO_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367841.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            65447..65587
                     /locus_tag="ACHDPO_000174"
     CDS             65447..65587
                     /locus_tag="ACHDPO_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367842.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            65584..65766
                     /locus_tag="ACHDPO_000175"
     CDS             65584..65766
                     /locus_tag="ACHDPO_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367843.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            65779..65973
                     /locus_tag="ACHDPO_000176"
     CDS             65779..65973
                     /locus_tag="ACHDPO_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367844.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(66006..66218)
                     /locus_tag="ACHDPO_000177"
     CDS             complement(66006..66218)
                     /locus_tag="ACHDPO_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367845.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            66346..66546
                     /locus_tag="ACHDPO_000178"
     CDS             66346..66546
                     /locus_tag="ACHDPO_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367846.1"
                     /translation="MKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDKY
                     LGEGFCGDSLFDDERILKEETE"
     gene            66543..66815
                     /locus_tag="ACHDPO_000179"
     CDS             66543..66815
                     /locus_tag="ACHDPO_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH/PUA domain-containing protein"
                     /protein_id="HFN3367847.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            66816..67001
                     /locus_tag="ACHDPO_000180"
     CDS             66816..67001
                     /locus_tag="ACHDPO_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367848.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            66979..67335
                     /locus_tag="ACHDPO_000181"
     CDS             66979..67335
                     /locus_tag="ACHDPO_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367849.1"
                     /translation="MKKVNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVL
                     KIEQNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIR
                     GGVCEISLVKRLPRTR"
     gene            67295..67771
                     /locus_tag="ACHDPO_000182"
     CDS             67295..67771
                     /locus_tag="ACHDPO_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFN3367850.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(67902..68630)
                     /locus_tag="ACHDPO_000183"
     CDS             complement(67902..68630)
                     /locus_tag="ACHDPO_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HFN3367851.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            68678..68956
                     /locus_tag="ACHDPO_000184"
     CDS             68678..68956
                     /locus_tag="ACHDPO_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367852.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            68958..69344
                     /locus_tag="ACHDPO_000185"
     CDS             68958..69344
                     /locus_tag="ACHDPO_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HFN3367853.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            69341..69721
                     /locus_tag="ACHDPO_000186"
     CDS             69341..69721
                     /locus_tag="ACHDPO_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFN3367854.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            69833..70285
                     /locus_tag="ACHDPO_000187"
     CDS             69833..70285
                     /locus_tag="ACHDPO_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFN3367855.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            70282..72009
                     /locus_tag="ACHDPO_000188"
     CDS             70282..72009
                     /locus_tag="ACHDPO_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFN3367856.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            72073..73260
                     /locus_tag="ACHDPO_000189"
     CDS             72073..73260
                     /locus_tag="ACHDPO_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFN3367857.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            73232..73801
                     /locus_tag="ACHDPO_000190"
     CDS             73232..73801
                     /locus_tag="ACHDPO_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFN3367858.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            73814..75178
                     /locus_tag="ACHDPO_000191"
     CDS             73814..75178
                     /locus_tag="ACHDPO_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFN3367859.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            75180..75458
                     /locus_tag="ACHDPO_000192"
     CDS             75180..75458
                     /locus_tag="ACHDPO_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFN3367860.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            75439..75765
                     /locus_tag="ACHDPO_000193"
     CDS             75439..75765
                     /locus_tag="ACHDPO_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFN3367861.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            75755..76093
                     /locus_tag="ACHDPO_000194"
     CDS             75755..76093
                     /locus_tag="ACHDPO_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367862.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            76083..76448
                     /locus_tag="ACHDPO_000195"
     CDS             76083..76448
                     /locus_tag="ACHDPO_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFN3367863.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            76455..77081
                     /locus_tag="ACHDPO_000196"
     CDS             76455..77081
                     /locus_tag="ACHDPO_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFN3367864.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            77081..77545
                     /locus_tag="ACHDPO_000197"
     CDS             77081..77545
                     /locus_tag="ACHDPO_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367865.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            77740..80049
                     /locus_tag="ACHDPO_000198"
     CDS             77740..80049
                     /locus_tag="ACHDPO_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFN3367866.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            80061..80765
                     /locus_tag="ACHDPO_000199"
     CDS             80061..80765
                     /locus_tag="ACHDPO_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFN3367867.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            80762..>82596
                     /locus_tag="ACHDPO_000200"
     CDS             80762..>82596
                     /locus_tag="ACHDPO_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFN3367868.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT        27826 a        13633 c        17384 g        23753 t
ORIGIN      
        1 aaaaggagtt agataggtgt tcaaaaatta tgtttcctca ctaaaaaaag aattttcagg
       61 ttatgatctt tcaagatttc agaaagatct tttggctggg atcacagtag ctgctgtagc
      121 attgccttta gccttggctt ttggggtatc aagcggagct gatgcggccg caggtttgat
      181 tacggctatc attgccggta tcgttattgg cggtttatca ggcggttttt atcaaatatc
      241 aggtccgaca ggtgcgatgg cagctatctt gatgtctatt gcggcaacaa agggaatgca
      301 aggtgtattg cttgctactt ttttagcggg tctattttta cttgcagcag gacttttccg
      361 attaggaaca ctgacttctt ttatcccagc acccgtaatt acggggttta cttcaggtat
      421 tgctatcatt attgcattag gtcagatcga taatttattt ggtgttcact cggaaggtac
      481 aaacgttatt gaaaaactaa gtagttatca aacgatagga tttccgataa acacagcctc
      541 tttgatcatg ggagggctag tcattttagg gatgtttatc tatccaaaaa aatgggcgaa
      601 acgaatgcct agttcgctgc tggctatcat tttggcaaca gcagttatgc tattgttcca
      661 tttaccagta gcaactgtgg gtaagattcc acaaacattg atcagtagta atcgtttgaa
      721 tatgggagat tttagctttt ctgccttgca acaagtggca gttccagcta ttagcattgc
      781 tttattagga atgattgaaa gcttgctatg tggtgcttcg gctggccgaa tggcaaataa
      841 gcccttagat agcaatcaag aattaatggc gcaaggaatt ggaaatctgt tgcttccttt
      901 ctttggcggg attcctgcta ctgcggccat cgcccgtaca agcgtggcca tcaaatctgg
      961 tgcacaaact agattagctg gtatgataca tgcagttgtc ttactgctct ccatgcttgt
     1021 ttttgcgcca gtgatgtcac agtttccaat gccagcactt gcaggtgttt tgattgtgac
     1081 ggcttggcgt atgaatgaat gggaaacgat caaggagcta tttactaata aatattggtc
     1141 agcagttcta ttgtttatcc ttacgatgat ttgtacagtt atctttgatt taagtattgc
     1201 tatcgtgatc ggggtgatcg gcggctgtgt attttttgtt gtcaaaagcg ctgctatcac
     1261 gatttcatta gaaacgatcg attggcaaag aatggggctg ccagaaacgg aaaagctgaa
     1321 taactggaca gtagtgtata ttagtggtcc actgtttttt atgtcttcag aaaaactcaa
     1381 aaataaattg gaagaactaa atcatcacga tggtgtcatt ttctccatgc gaggcgtacc
     1441 aagtattgat ttgacggcac gtgcagtttt tgatgaattt caagaaaaag cagagcaaag
     1501 aggacaaacg attatctata cttccttgca gccagaagta gaaaaacaac tttctcactt
     1561 gtgggaacat acattcacgc atcaacatca aacagttgct catgcgttga cagctttaca
     1621 tgcgaaatat actgcaatta gccattaaaa caatgaaaaa gaacagacaa gactgtaaac
     1681 tgaagatttt atggtcttgt ctgttctttt taatattgct gtaaaagtga agctagtact
     1741 tgccagtctt gatggataac aggtacaagg gagcgattgt agaaaatagc tgctggatga
     1801 aaaagtggaa gaattcgata gtttttttct gaccattcgt aggcatcctt ttgttctgtt
     1861 aattgtaaga caggccctgt atagagttga ccatgatttt tggtaaccgt atattctttg
     1921 ccaagtaaac gttgaagacc aatgtttcca agtgtcgcaa ttaattttgg ctggaccttc
     1981 atcagttcgt aatccaatat tggtgcatgc gcaaatactt cggaacgagt aggtgtccga
     2041 tttggataaa cagtttctga ctgttgtgtc cgtttattga tccgatgagt cacgcgatac
     2101 gggcggctcc ttacagcact ggtgatatac acctcttctc gtgttaagcc agttgaagaa
     2161 agtgcctgca tcaattcttt tccagcttga ccgctaaaag gaacatgcgt atcaatctct
     2221 gttttccctg gggcttctcc cacgagcatc agtttaggat gaagaggtcc ttgcccagcg
     2281 ataaatcctt ctacaggacg gccgttcatt cttaaagaag cttcttgtat cagttctttt
     2341 gggtattcca tttatgctcc tcctttttct tttattataa gaataaaaga aacacaatgc
     2401 gactatttta tttggtagaa ctgtgaggat agaaaagcag aagtattgct tgaatttttg
     2461 ttttactttt tgattttaaa tttagttgac taacggttgc tgttctggta agctagtact
     2521 gttgtaattg tggactccac agctacaacc gctcagaaca agtaataagc acagcatatg
     2581 ctgtcacttc ggatggcgag tctaagtata tcagaaggag gtgctttata gcatgtacgc
     2641 aattattaaa actggtggta aacaagtaaa agttgaagtg ggacaagcaa tctatgttga
     2701 aaaacttgac gttgaagcag gagaaaaagt tgtttttgac gaagttatct tagtaggcgg
     2761 agaatctaca aaagtaggcg ctccaactgt tgcaggtgca actgttgaag gtactgttga
     2821 aaaacacggc aaacaaaaga aagtcgttac tttcaaatac aaacctaaaa aacattcaca
     2881 ccgtaaacaa ggtcatcgtc aaccatatac aaaagtggtt atcgacgcga tcaacgctta
     2941 atagcgtttg agaaagaagg cctatatatg atcaaaggaa catttaagcg aaatgacgca
     3001 ggtcagatcg tttcattcac tttgaccggg catgctgatg ctggtcctta tggaagtgat
     3061 atcgtttgtg cgggtgtttc tgcgttagcg atcagcactg tcaacgggat tgcctcatta
     3121 gccggttttg agccgattgt tgaaatgaat gaagaagaag gcggttatct ttataccgaa
     3181 gtcacttcag gaatgacaca agaacaaaac aatattgctg agattctatt agaaaatctt
     3241 ttattaggat tacaatcgat agaagctgaa aactcagaat atatccaaat taaaacaatt
     3301 aatgataaat aggaggtgca gaccatgttg ttatctatga atctacaatt atttgcccac
     3361 aaaaaaggtg gcggttctac atctaacggc cgtgactcag aatcaaaacg tctaggtgct
     3421 aaacgtgctg atggacaaac agttacaggt ggatcaattc tttaccgtca acgcggtaca
     3481 aaaatctatc caggtgtaaa cgtgggtatc ggtggagacg acactttatt tgcaaaagtt
     3541 gatggcgtag tacgtttcga acgtaaaggc cgtaacaaaa aacaagtgtc tgtttatcca
     3601 gtagctcaag aagcttaatt gaatcttatg attaaagagg ttgtgacaag acttttgtca
     3661 cagccttttt tgtttataaa aataaaagtt gtagtggagg ctacgaagtt tactttgtct
     3721 ttttacactt aatatttttt tgccaatttg gaatcaggat gttttgataa ctatcgtttt
     3781 caattgatgg aagctatatt gtttgctatc agtgaaataa ttatatggta aacagtgttc
     3841 tttttcttgt ttccattata aaaatcgtat cgggattttt cgttctttta aattgaacat
     3901 ttctatctat ccgcgtgtta tcaacaaaac aaaatcaggt aaatagttga cgaaacagaa
     3961 ataaatacat agtattatgt tttgaagcct aagtacaata gtctatagaa aaggagcgat
     4021 accattggca aaacgcattg accgaattta tatgtatgtc aaagaaaaaa ccgctcattt
     4081 aacaaaggca gaatatgatc aaggagtaac aacacaggaa attgctgaag tgttagggat
     4141 tcagcgaaca aatagcagta aagatctgaa tcagctagtg cgcgaaggaa aactgataaa
     4201 gacagacgga cgaccagtac gttacatata tcaaacactc gttacgcacg taaagccagt
     4261 tacaaaacat gtagtcagtt acaaagaaac gccggtctct gaagaaaaaa atacactcca
     4321 aatagatact aaggatatct ttgcaaaaat cattggagct aacggcagca tgaaaaattc
     4381 agtggaacag gcaaaagctg cgattttgta tccgccaaga ggattaaatt gtttgattac
     4441 aggacctacc ggatcaggaa agacttattt tgcacacgcg atgtatcatt ttgcaaaagc
     4501 gcatcatgta atagatgagg aaacggaact gattgttttc aattgtgctg attatgccaa
     4561 taaccctgag cttttgatga gtcatttatt tgggtacgca aaaggtgctt ttacaggcgc
     4621 agatgaagaa aaaatgggga ttatcgatca agcggatggc ggtatgctgt ttttggatga
     4681 gattcaccgg ttgccgcctg aaggtcaaga aatgatcttt tactttatgg atcatggaac
     4741 ttacagtcgt cttggggaaa caacgaaatc ccatgaagca aatgtacgga tcgtaggtgc
     4801 gaccacagaa gacccaggtt cttctctatt agaaactttt gttcggcgta tcccaatcaa
     4861 tatcaaactt ccggcttttg aaaaacgtcc tgcaaatgag aaagtcgatt tagtaaaaat
     4921 catgattgcc cacgaagcaa accgcacgca gcgaaagatt tctttgacag aagatgtagc
     4981 aaaagcattg atcggcagtg tgacctatgg aaatatagga caattgaagt caaatatcca
     5041 gttagtatgt gcacgaggat ttctaaatca tatgcaatca cccgaaatct cgatcacaat
     5101 cgatgatttg acagaaggga ttcgtagcgg attgattcaa ttagcaagca accgcagtgc
     5161 aatggcagag ctttctaaaa tattggagcc aaagataact gtagcaccaa atgatacgat
     5221 catgaaaatc caatcggact cctatgagtt accttataat ctatatgata tcatcggaga
     5281 taaagcagct ttactgaagt cggatggttt ggatcaagaa gcaatcaatc atttcatttc
     5341 tacagatatc aacatccatc tgaagtcttt ctataaagac catggttttt cttttaatgc
     5401 agacagcaaa ttagcagaat ttgtagatcc gaaaatcata gaagtgacca atcagattta
     5461 tgtaatggtc aaaagatctt taccatatga gtttcagcaa aactttattt atgctatgag
     5521 cttgcatatc agttcttttt tgaaaaaaat caacttagga gaagaacggc atacgaatga
     5581 taacatccgt gagatggctt ttgattttcc agatgaatat gctgttgcga aagaagtgcg
     5641 tagttatatc gaaacgtatt ttcaagtgga gattccagaa agtgaagact attacttgac
     5701 cgttctactc gtctcgttac gggcaaatca agcaagcggc agaatcggtg tagtcgttgc
     5761 agctcacgga aacagcacag caagcagtat ggtccaagtt gtccaacagt tgttagatgc
     5821 agagaacgta cgagcagtag acatgccttt ggatatggat ccgaaaacag cattggaccg
     5881 aattgaacgc aatgtacaag aagtagatga aggaagcggg gtcatactct tagtagatat
     5941 ggggtccctt gcgtcgttta attcgcaaat tcaaagagac actggaattc cagtacgtac
     6001 tgttgatatg gtaacaactt ctctagtttt ggaaactgta cgaaaggtct cagtattagg
     6061 gacagatcta gatatgttgc atgaatcatt gaaaaatttt cgaggttacg cagaaatatc
     6121 ttctgtagaa tctgttcagg aagcaaaacc tattcataag aaaaaagctg ttttggctat
     6181 ctgcgcatct ggcgaaggta cagcacaaag aatcaaagaa ttgatcgaac gagcggtaaa
     6241 caagcgtcaa gaaacagaat tagaagttct agctttgtcg attgtggaag tgaaagaaga
     6301 actgccagtt atccaaaaag aatatcagat catagctact actgggatta ctgatttgaa
     6361 tatccaagcc ccatttattc ctttagaacg ttttattgat caaaatatcg aagtcatttt
     6421 ggatcagttg ctgatggaat cagaattgga ggaaactgaa ttcatctccc tagatgaaga
     6481 gtcagctaaa aatacgtgtg ttgagtttat ctctgataac ttcatcttta ttaatggtag
     6541 taagttaatc gatccaatgt ggcaattttc tacacaaatc tctcagacga cgggaatcgg
     6601 cgatgaagaa tatggattca aaatcaacct agtgatgcac acagcaggaa tgatcgaacg
     6661 tattattcgg aatgaaccat tgactgtgga agaaaacgaa ttgacaaata caacgaatga
     6721 tcctctttat agccaattgg cagcctcagt tgttctgttg gaagatcaga taaaagtaaa
     6781 agtgccgata gaagaaatgt attatctgct acgtctagtc cataatcagt tagataaaaa
     6841 agaatacact gtgccatgaa tacacaaaaa cgatacactt ttatagtgta tcgtttttgt
     6901 gtattggtta agaatccttt aaattcaatt agtgtatcgt aaaaaagttg gcacgctttt
     6961 tgcttatagt agtgtgtgct aggaggtggt tgttcacaca gaaatgatag gggtttctgt
     7021 gaagtagtga ggaagaagga gttttgcaga tggatattcg attggcacgt atagatgatc
     7081 gtttaatcca cgggcaagtc gcaacagttt ggtcgaagca aacaggtgtt gaacgtatca
     7141 ttgtgatcag cgatgtagtc gctcaagata aattgagaaa gtttctacta aaagaagctg
     7201 caccgccggg gatcacagca aatgtaataa ccgtgcagaa aatgattcaa atctatcata
     7261 gtggattatt atcacgagca aaagtgatgc ttttattcac caatccccaa gatgttgaag
     7321 cggttgtccg ctgcggtgta cagttgaagt cgttgaatat cggcggtatg agttttactg
     7381 aaggcaaatc aatgattacc aattttgttt cagtaaatca acaagatatt gattcctttc
     7441 gttacttgaa cagtcaagaa gtggagttag agattcgaaa agtacctgct gacaggaaaa
     7501 tccttttgat ggaactacta gcgaaaatca aaaaggtgta gcaagaatgg ttgttggaaa
     7561 aggtcaaata attctgttgt aatggttagc aattattaat atttttgaat ttgttacaac
     7621 aaaagtaaat aggaggtata aatatggtag ggattatcct agcaagtcat ggacaatttg
     7681 ctgaaggaat cttacaatcc ggttcaatga tctttggcga acaagaaaac gtcaaagccg
     7741 tgattttgaa accaagtgaa ggtccagatg acttgagagc caaattggaa gaagcggttg
     7801 cttcttttga taatcaagac gaagtgttat tcttagttga tttatggggc ggaacaccgt
     7861 tcaatcaatc aaacacatta ttcgaagagc acaaagataa atgggcaatc gtcagcggtt
     7921 tgaatttacc aatgttgatt gaagcctacg catcacgctt ttcaatggaa tctgctcatg
     7981 aaattgcagc acacatcatt gaaacagcaa aagacggtgt aaaagtaaaa ccggaagaat
     8041 tagaaccggc agaagcaccg aaagcagcag ttgaagacgc acaacctaaa ggagcacttc
     8101 cagaaggaac tgtggtcgga gacggaaaaa tcaaatatgt attagcacgt gttgactcac
     8161 gtctgttaca tggacaagtt gcgacagctt ggacaaaagc agtgcaacca aaccgtatta
     8221 tcgttgtttc agatgcagta tcaaaggatg atctgcgtaa gagactaatc gaacaagctg
     8281 ctcctccagg tgtaaaagca aatgttattc ctattagcaa aatgatcgaa gtagcaaaag
     8341 accctcgttt tggaaatacc aaagcattgc ttttatttga aaatcctgaa gacgtattga
     8401 cagctgttga aggtggcgta gacatcaaag aattaaatgt tgggtcaatg gcgcattcgg
     8461 tcggtaaagt cgttgtaagt aaagtattgt ctatgggaca agaagacgtt gaagcgtttg
     8521 agaagcttga acaaaaaggt gtgaaattcg atgtacgtaa agtacctaat gattcacgcg
     8581 ataacatgga tgatattttg aaaaaagcaa aagctgaatt agcaaaagcg taataaataa
     8641 tattaaaatt tataggaggc ttatcatgtc tattatttca ataattttag tcgtattagt
     8701 tgcctttcta gctggtatgg aaggtattct tgatgaattt caatttcatc aaccactagt
     8761 ggcatgtaca ttgatcggtt tagttaccgg taacctcgaa gctggtatcg tacttggcgg
     8821 tacgcttcag atgatcgctt taggttgggc aaatatcggt gccgctgtag caccagatgc
     8881 tgcattagca tcagtagcat cagcaattat tttagtttta ggtggacaag gtgttaaagg
     8941 tgttccttct gcgatcgcga ttgccgttcc tttggctgtt gcagggttgt tcttaacaat
     9001 gatcgtacgt acaatcgctg ttccaatcgt tcatttgatg gatgcggctg ctgaagaagg
     9061 aaacatccgt aaggttgaaa tgtggcacat cattgctgta tgtttacaag gggttcgtat
     9121 cgcggtccca gcagcagcgt tgctatttat cccagcacaa actgtgcaat cattccttga
     9181 atcaatgcca gcatggttaa cagatggtat ggctatcggt gggggaatgg tcgtagctgt
     9241 aggttacgct ttggtaatca acatgatggc tacaaaagaa gtatggccat tcttcgttat
     9301 tggtttcgtt gtagctgcaa tttctcaatt aacattgatt gctctaggtg ctttaggtgt
     9361 tgcattagct cttatttact tgaacctttc taaaatgggt ggttcatcaa ataatggagg
     9421 cggaagcaac tctggtgacc ctttaggcga cattttgaat gactattaat cttgaaggag
     9481 gaaaataaaa tggcagaaga aaaaatcaaa ttatcaaaaa aagatcgttt agctgttgcg
     9541 tggcgctcta ccttcattca aggttcatgg aactacgaac gtatgcaaaa cggtggctgg
     9601 gcattttcta tgattccagc aatcaaaaaa ttatacaaaa caaaagaaga acgttctgca
     9661 gcattaaaac gtcacttgga attctttaat acacacccat acattgcttc tccaatttta
     9721 ggggttacat tggctctgga agaagaacgt gcgaatggcg cgcctgttga tgatgtagcg
     9781 attcaagggg ttaaagtagg tatgatgggt cctttagctg gtgttggtga cccagtgttc
     9841 tggtttacag tacgtccaat gctaggtgca ctaggtgctt cattagctat gggaggaaat
     9901 atccttggac caatcatctt cttcttaggt tggaacatta ttcgttgggc attcatgtgg
     9961 tatacacaag aatttggcta caaagctggt tctaaaatta ctgatgacct ttctggcgga
    10021 ttgttacaag acgtaacaaa aggtgcttca attttaggga tgttcgtatt agctgccctt
    10081 gtacaaagat gggtatcaat caaattctta ccagttgtat caactgtaaa attagataaa
    10141 ggtgcttaca tcgaatggga taaattgcct tcaggtggtg aaggaatcaa gagtgcattt
    10201 gaacaagtta ataatggctt agccctttct cctgaaaagg taacaacatt acaagacaac
    10261 ttagaccaat tgattcctgg tttagctgca ttaggattaa cattgttatg tatgtggttg
    10321 cttaagaaaa aggtttctcc aatcgttatc atccttggtt tattcgtagt cggtgttgtt
    10381 ggacacgtca tcggactttt ataatccata aaaatatagc tcgggcgttg tcccgagctt
    10441 tttttatata gtatactgtt cataaacaaa tatctggagg gagaaaatgg ttcaatcaat
    10501 caatacaaaa gtagacttgg taattgatgc tacttcgttt acgggtctga cagattacgg
    10561 gcaaatcatg ataggtaata atggttttga gttttaccat gcgcgagata gacgcaaata
    10621 tatccaaatt ccatgggaag aagtggatta tgtactagca tcagtcatgc taaagggaaa
    10681 atggattcct cgatatgcca ttcaaacgaa aaaaaatggt acatacacat tttcttccaa
    10741 agaacctaaa aaagtgcttc gtgcgatcag agaatatgta gatgaagata gaatggtaca
    10801 atcattgagt ttctttgatg tagtgaaacg tggtattcgt agtatgttta aacgcaagta
    10861 aaaaataaag aaaacttcta agaggaggtt ttctttattt ttttactttg cagaagaaaa
    10921 tatgaaatag caaaaccaat tatttgtccc ctttaaatcc catatgctaa aattgattag
    10981 caaagaagga ggttatatta tgagttggtt atggacattg attgttggag ccgtgatcgg
    11041 agcaattgca ggtgcgatca ccagtaaagg aaattcgatg ggctgtgtaa cgaatatcat
    11101 tgctggacta gtcggttcaa gtattggaca agcgattttc ggcgaatggg gaccaaaagc
    11161 tgcaggtatg gcacttattc catctatttt aggcgcagtg attttggtag cagttgtctc
    11221 atttttcttt ggaaaacgat cataagtttt tacaaaatag taaactaaaa ggagttgcag
    11281 cgagactgtg actccttttt ggctttattt atttaaaata aaaagaagtt ttccggaaat
    11341 ttttatttaa ctgtcgtgta cgaagaaaag tttgctataa tggaaaaaag cgtgcaaaga
    11401 aagagggagt ttcattatga tgctacgtgt agaaaaattg cgcaaaaaaa tgcaagaaga
    11461 aaatttggat tcatttttgg ttaccagtcc gtacaatctt cgttacttaa cgaactttac
    11521 aggtacgaca ggattagctg ttattacttt ggaaaaagca ttttttatta ctgattttcg
    11581 ttataccgag caggcggcag cgcaggctca agggtttgaa attattaaaa atgtcggacc
    11641 tatttttgat gaggtagcaa acttagtacg caaagaagaa ctgcactcat tagcttttga
    11701 ggaaacaaca gtctcatttt tagaatattc ggttttagaa gaaatcatcg atgcggaatt
    11761 agtacctgtt tcacagatga tcgaagaact cagagaagtg aaagatgaag aagaaatcgc
    11821 tattatcgaa aaagcatgtc atattgcgga tatggcatat gatcacatcc tgaaaatgat
    11881 ccaaccgggc atgactgaga ttgaagtcgc aaatcaacta gacttttata tgcgttctct
    11941 tggcgcttca ggtgtttctt ttgatacgat cgttgctagc ggattgcgtt cggctatgcc
    12001 gcatggtgta gcaagcaaaa aaatcatcga acaaggtgac ttgatcacat tggactttgg
    12061 ttgctattac gaagggtacg tttccgatat gacacgtaca ttcgctattg gtgatcctgg
    12121 ggaaaaatta aaagaaattt atcaaatagt cttagatgct caattagcag ttattgatgc
    12181 tgcaaaacca ggaatgactg gtgtccaatt agatgcagtt gctagagatt atatttcaaa
    12241 acatggttac ggggaagcat ttggacattc tacaggacat gggatcggtt tagagatcca
    12301 cgaaggacca aacgtttctt ctcgtgcaga aaagcaattt gtaccaggaa atgtgatcac
    12361 tgatgaacca gggatctact taccaggaat cggtggagta cgtattgagg atgacttgtt
    12421 gatcacagaa gatggaaatc gtgtgttgac tcgttcacca aaagaattga tcatcttata
    12481 gtttcatcaa tagaagaagt aagcgtaaaa atcagtgttc acagactttg ttatagaaaa
    12541 tcactcgatt taatgataca ctatagaaga acttttaagc tgtaagagat aataaagttg
    12601 ggtgttttct ccaattcata gcagtttgca gctgatcggc ggcagttttc ttaccacgtg
    12661 atcactatgc cgcatcatag agaattcgga tgtatctcgt gcttaggcaa agggaggaat
    12721 aaataaatgg cagatgaaaa aaatttgatt ttaaacgcaa accaagattt aggagagatc
    12781 gtgatcgctc ctgaagtcat cgaagtaatt atcgggattg cagcttctaa agtagaaggc
    12841 gtatacggaa tgcgcggaac ttttgccagc aatgtcactg aattattagg acgtgcagct
    12901 cacggaaaag gtgtttactt agcaaacgag gaagatggct tgaaagtaga tctttactgt
    12961 tatctagaat atggtgtttc agttcctaaa gtagcaatgg aaatgcagga acgggtcagc
    13021 cagcaagtcc ttttcatgac ggatatcgat ttatctgaag tcaatatcca tgtagtagct
    13081 gttgttcctg aaaaattaga acaaccaaca atcgaagaac tttttgaaga cgaagaggaa
    13141 gagaatgaat aaagaattat caagacacga gattcgggaa atggcattgc aggctttatt
    13201 tccattagac ttcaatgcag acctaacaaa agaagatgcg attttcaacg caatcgaatt
    13261 agaccaccgc gacatgatca acgaagatga atcagagttt gttcctgttt atcttgatac
    13321 gctagttggc ggtgtctgtg caaaaaaaga tgaattggat aaagtgattg aaaaacattt
    13381 aaaaaacaat tggcacatca atcggatctc aaaaatggat ttggtgatct tgcgtatcgc
    13441 gatttttgaa atgacttatg tgacagatgt accagcggct gttgctttaa atgaagcaat
    13501 cgagttggca aaaacattta gtgatgaccg ttcacgtaaa ttcgtcaacg gtgttttatc
    13561 caatgtattg aaagaattag aagctggggc gtaagtccta gcttttttct atgaatcatc
    13621 ataaacctgt tataaatcgg gaaaattcta tggtagaatg aaaacacaaa aaatatctgg
    13681 gagtggttag atggcagaat tgattaacgg aaaagaatta gctgaaaaaa tgcaggcaga
    13741 gattgctgaa aaaatccaaa aattgaaaga taatggtatc catcccggat tagtcgtttt
    13801 attggtaggg gaaaatccag ccagccaaat ctatgtaaga aataaagaac gtgtagcaaa
    13861 agaaatcgga atccattcat tggtagagcg ttatcctgag acgatttctg aagacgaact
    13921 acttgcagaa attgaaaaat acaatcaaga tcctagtttt catggtatat tggtccaatt
    13981 accattgcca aagcatatag atgaagaaaa gatcctgtta gctatccgcc ctgaaaaaga
    14041 cgtagacggt tttcatccga tgaatttagg cagactcctt gcgggtaaac cggacaagat
    14101 tccttgtact ccatacggca tcatgaaaat gtttgaagct tattctatcg atccggcggg
    14161 taaacgagca gtagttatcg gacgaagcaa tatcgtcggt aaaccgatgg ctcagctact
    14221 cttgatggca gatgcaactg ttactgttgc tcattctaaa accgaaaatc tggctgaact
    14281 ggcacaagaa gcagatattt tagtcgtagc aataggacgt ggacattttg tcacaaaaga
    14341 attcgtaaaa ccaggtgctg tagtgataga tgtagggatg aatcgtgatg ctaacggtaa
    14401 gctgatcggt gatgtgaaat ttgatgaagt ggagcctatt gcaggctgga tcactcctgt
    14461 gccaaagggt gtagggccaa tgactatcac gatgctgatg tatcaaaccg taaaatctgc
    14521 cgaagctttt ggagcaggtg aatagatggc acaagaatat ttaactgtca ctacattaac
    14581 gaagtatttg aaaagaaaat ttgatgccga tccttattta gaacgcgtat atttaacagg
    14641 cgaaatatcg aatttccgtt tacgtgccaa tgcccatcaa tatttcagct taaaagatga
    14701 ccatgcaaaa atatctgcta ttatgttcaa aggagcattc caaaaattac gattccagcc
    14761 aaaagaagga atgaaagtcc ttgtcgttgg gcgtatttca ttatatgaag cgggaggttc
    14821 ttatcaaatc tatgtagagc acatggagcc tgatggaata ggtgctttat atcaagaatt
    14881 ggaagaacga aaagaaaagc tgatgaagga aggccttttt caagggccta aaaaaatgct
    14941 gccacgtttc ccaaagcgaa tcgcggtcct taccagtcca agcggagcgg ttatccgcga
    15001 tatcatcacg acggtgaaaa gaagatatcc aattgtccaa ttggttttgt tcccaacagt
    15061 tgtacaagga aaccaagcag cggacaatgt tgtcaggaat atccagagag tagaagagat
    15121 gggcaatttc gatacaatga tcatcggtcg tgggggtggt tcgattgagg atttatggcc
    15181 gtttaatgaa gagcgggttg ctcgggcgat ttatcaagct aatacgccgg tgatttcatc
    15241 tgtaggacat gaaacagata ccacgatcgc tgatttagta gcagatgttc gggctgccac
    15301 tccaacagca gctgcagaat tagctgttcc tgttttgtca gaagagttga tgcgcattca
    15361 agaacggcaa gctagattgc agcaggcgtt tgtacgccag atccagcgca aacaagaacg
    15421 gttcgagcgt gctcgacgtt cctatgtatt tcggcagcct gaaagattgt atgaaggtca
    15481 gaccatcaaa ttagaccagt tgaaacagcg attatatcaa gctacacagc aaatttatca
    15541 tgcgaaagaa aaacaaacga tcgcattaag ccaccaattg gaacaagtgg ctccgcttta
    15601 tcgagttaaa gcagctcgcc aagaaactgc ttatctagaa aaacgcttag aagagaaaat
    15661 ccaacaatat atgaaacaac agcagcagcg ttttgctcaa gctgttcaat ctcttgattt
    15721 gttgagtcca ttgaaaatca tgggaagagg ctacagctat acgacgttaa atgatcaagt
    15781 agtaaaaagt gtcaccgaga ttcatcaagg ggatttgctg acgatccatt atcaagatgg
    15841 aatcgttaaa ggacaagtac aagagataga caaaggagaa taaaaatatg gaaaatccaa
    15901 cttttgaaga gtcactgcaa gaattagaaa aaattgtcat gcagttagaa caaggagacg
    15961 ttccattaga atcagctcta gattcgttta aacgaggaat ggaattaagc aaacattgcc
    16021 aagatacatt agctaaagca gaagagacct tgacgaaaat gatgacagaa tcaaatgaag
    16081 aagttgattt tgacggaaac gaggaaagct gagatgagat taactgactt ttcagctatt
    16141 catctacctg ctgtagaaaa agaaatcttg tcttttttag atgagcatac aacggataga
    16201 ggactctatg atgcgatgag ttattcagtg aaagcaggcg ggaaaagaat acgtccctta
    16261 ttacttttaa cggccgttgc ttcctttgat gagcctattg atgttcccgt ctatcaagta
    16321 gcagctgctt tagaaatggt gcatacgtat tccttgatcc acgatgattt gcctgcgatg
    16381 gacaatgatg atcttcgtag aggaaaacct accaatcata aagtattcgg cgaagcatta
    16441 gctatattgg ccggagatgg tttgcttaca ggagcattcc agctaatcag tatggcacac
    16501 ttaggtaatt ctcctaagct tctgctgctt cagcaattag ctgtttgtgc gggatcacaa
    16561 ggtatggttg ctgggcaagc tgcagatatc gagggcgaat cgaaaaagct ttctttagaa
    16621 gaattagcat ttattcatga aagaaagaca gggcatttga ttcgttatgc cttgctggct
    16681 ggtggcatat tagcgaagca acctgaagaa atcttattgc tacttcaacg attagccgaa
    16741 catttaggtt tagcttttca gataagagat gatctactcg atgtgattgg tacaacgaaa
    16801 acattaggga aaacagctgg taaagatgaa cgtatggaaa aaaatactta cccgcgttta
    16861 ttaggcctag aaaagacacg tgaggcgttg gagattgagc tgttatccgc caacaagatc
    16921 atagacaaat tagaagagga cgttttttct tttgatggcg ggctgatgcg ccagatgatc
    16981 aagcaatttg atgtggagaa atgagggaaa gaatggaaaa agaacgcgta gatgtattag
    17041 cggtcaaaca aggattattt gaaacaagag aacaagccaa acgttcagtg atggctggtt
    17101 tgatttacaa cgaaaaaaac gagcggtttg ataaaccggg agaaaaaatt ccagtgagta
    17161 gtgaattaag agtcaaaggt aaaaaacttc cttatgtttc tcgaggggga ttaaaattag
    17221 aaaaagcact caaagcattt gatctatctg ttgaaggaaa aacattgtta gatattggtg
    17281 catccactgg cggatttact gatgcagctt tgcaaaatgg cgcaaaaatg agttatgctt
    17341 tagacgttgg ctacaatcag ctagcttgga aaataagaca agatcctaga gtcgtcgtaa
    17401 tggaaagagt gaattttcgt tatgcaaaac ccgaagactt taccttagga attccagaag
    17461 ttgctgttat cgatgtttct tttatttcac taaaactgat gctgcctcca ttacatgcta
    17521 ttttaaaaga agagggagaa gtgattgctt taatcaaacc ccaattcgaa gcaggcagag
    17581 aagctgtagg gaaaaacgga attgttcgtg accctcagac ccatcaaaaa gttttagaag
    17641 acattttgtc atttgcggca caaggtggat atgatgtgct ggaattaagt tattctccga
    17701 tcacgggggg agaaggaaat atcgagttct tggctcactt gaggaaagta cccgaaagcg
    17761 gaacaatcaa ttcagctatt aatatggcag aagtggtttc aaatgcacac gaacagtttg
    17821 accataaata aattgtaact gtgaaaatca agtgagaagt atgcggattc ttctttatta
    17881 taccaaggaa ataagctatc attgattaag aagaatatgc taaggagcga agacgtaatg
    17941 agaaaaaaag atcggcatcg tttgattact cgattgttga gtgagcaaga tatccgaaag
    18001 caggaagaat ttgttgaaat cctgaaaagc aaaggaatat ctgttactca agctacgatt
    18061 tccagagata taaaggaact gaaactgatc aaggtaccgg cttcagatgg cggctaccgt
    18121 tatagcatac cagctgaaac aaacgaagat gtaaatacta aattggaaaa actattaaaa
    18181 gacgctttcg tggcagttga ccaaatggaa aaatttgtta ttttgaaaac attgccggga
    18241 aatgcttcgg cagcagcaaa tttgattgat aaacgttaca agaaagaatt attttcgatt
    18301 atcaatgatg acgataatgt tttgatgatt acacgaactg aagaccaggc agttttattg
    18361 aagaaagact tcctgcatta cctttaagtt gaggagcgaa tgtgatgcta caagaaatca
    18421 gtattactaa ctttgcgatt attccggaat tgcggctttc ttttcacgaa ggaatgaccg
    18481 cgctgaccgg agagactggt gcgggtaaat ccattattat cgatgcttta ggtctgttag
    18541 caggaggaag aggttcaagc gattatatac gtcaaggagc agaaaaatgt gtgcttgaag
    18601 ggttgtttga actaccaaaa caagaaggat tctctgaact gatggttgaa ttagggatcg
    18661 aaacagatga ggacaatctg attgttcgac gggatatgtc cttaactgga aaaaatgttt
    18721 gtcgagtgaa tggtcatatt atcacattag ctaatctgag aagaatcggc agttatttag
    18781 tagatatcca aggacaaaac gaacatcagg aactgctcca gcctgaatca catcttgctt
    18841 tattggatcg ttttggagat gtagctttcc aacagaagaa aaagagttat cagcaagaat
    18901 atatctctta tcgtgagctg gaaaaaaggg tacgaaaagt gcagcaaaat gaaaaatcct
    18961 atgttcagag aatagatatg ctccatttcc agcaagaaga aatagctgct gctgatttgc
    19021 aagtcggaga agaagagaaa ttaaaagaag aaagagaaaa acttagcaat tatcaaaaaa
    19081 ttgctgatgg attagctgca ggttacggag cactgacgaa taatgaacaa aacagtgtag
    19141 atggtgttgg cttggccgtt tcagaactgc aagggatcgc ccatctagat gtggagtatg
    19201 aagcaattta tgaaaatatc caaagtgctt actatttgct gcaagatgca atcggcgata
    19261 tgagtcgtca gattgattta ttggagttag atgagagtcg tttagaagaa gttacgcaac
    19321 gtttagaatt aatccgacag ttgaaacgta aatacggcga atccattgag tcaatattgg
    19381 cttactatga cgaaatcacc gaagagctag cttcttctga tttttcagaa ggtcaattgg
    19441 acaaaatgaa agaggaacta gagcaaaaag agcttctact tcagcaacaa gccgcagatc
    19501 ttcatgaagc gcgtaaaaaa atcgcaaaag aattggaaaa atccattctg catgaattga
    19561 aaagtctgta tatggaaaac actgagtttg aggtacgttt cttaaaagaa gaaaatagac
    19621 aattgaatca tgatggattt gaccaaatcg aattttacat tacgaccaat ccaggagagc
    19681 cactgaagcc tttggtgaaa gtcgcttctg gtggcgaact gtctcggatg ttgcttgctt
    19741 tgaaaactat tttttcttct gagcaaggtg tgacaagtat tatttttgat gaagtggata
    19801 caggtgtgag cggaagagtt gcacaggcca tcgcagataa aatttctcaa atatcgaaat
    19861 actctcaagt tttgtgcatc actcatctgc ctcaagttgc tgcagtcgcc gactatcaat
    19921 attatattgt gaaagcagtg attgatggac gtacgcaaac ttctgtttca gagttgaaaa
    19981 caaaagaaag agaagaagaa attgcacgta tgctggctgg aagtgagatt acaaaactca
    20041 cactcgaaca tgcaaaagaa ctattgaaac tcgcaaaaag gacctgagcc acctcgcagt
    20101 ggttcaggtc cttttcagca gctgatagct atattttatt tttacatgac actcattaca
    20161 gcagtcaata caacagatcc aatcgttaaa atcagcattg tccaaatgac aaattttgtt
    20221 actttagcaa aagtacttgt ttgttttttt tcacgcattg ttttcaacct cgtcattaat
    20281 tagttgattc aagtgtacaa tcttttttcc atttccacaa gagggctttt ttataaaaac
    20341 ttcccttttt ttaaataata ggtagttacg atacaaataa ataatgttaa tagaactagc
    20401 catataaagg catcatccct ttcagcaata ggtaacttaa tgttcattcc atagatactg
    20461 ccgacgattg tcggtatagt taaaataatc gttaaagaag ttaaaatttt cataatatta
    20521 ttcagattat tcgatacgat tgctgaaaaa gtctgattca tttgttctac tagttttaat
    20581 tgaatgcgag aagtagtcat tgcctgctct gtttccacca atacatcacg taaatgattt
    20641 ttcaaagcat gattttcttg gaaaagttta ttttgcgcta gttctttcaa tgcatctaaa
    20701 ttagcagaag tcgcttctct gaaataaacg aggctttttt ggatatccat gatttgataa
    20761 agttgtttgt tttcagtgga tacttgaagt ttggcttcca aagtatcgca ttgagattga
    20821 agcgtagcta aataactgtt gtaagagagt gtgacctgcc aaatgaattg aaagaagata
    20881 ttgagattag gcgaaatatc actttttgga aaggtctggc taaagacttt ctttaaaaac
    20941 agtggttcat gattcgtaat tgtgataagc ttctttttgg gcgtcaaaat aatagagagc
    21001 gggtatgtat ccacttgaaa ataaccgcta ggacttgttt tagcaaaagg atattgtaac
    21061 aataataacg ctggctttgt caactttgat tgattgaatt cttctgtacg ggaattttct
    21121 gcatcgtcca atatggaagt gatgtaatct gacggaattt caaattgatg tgtcagctga
    21181 tgaatctctt cttgattagg acgttctaca caataccaga tcgtttggtc agtttccttt
    21241 ccggtattac gcagtttctc attatctaat gtaaaatatt tgatcatgat tttcctcctg
    21301 ttgcctgttt cttttattat aacggatagg gaattggaat acatggaatg tgtttgtaag
    21361 atatagaata taactgcata aatttaaata aaatgaaaca gttgtgtaaa gtatatacag
    21421 tatacttgaa gcaacgataa aaaaggagtt tacgttcatg ggcacattca caccacttat
    21481 cttgttttgg tatatttacc cggtaatcgt tttgtttggt tgccaatttc ttgtaaaatt
    21541 attttcgtta aatcgtcgtt ttaaaataaa agcccctgat ttggcgattc cttttttgtg
    21601 gggcggtatg catgcattgt ctagaaatac agggacaatt tctatcttac cgtttttctt
    21661 tatttctgtt ttgctaatgg gaatttgtat tgctgttttc caagcatatt attatgaaga
    21721 aattatttat ccgcgttatt tcaagatgac ttggcgtttg gtttttctgt tgacaatcgt
    21781 cttgtacgct gtcttgatca ttgtgaacat actttcttac ctatgaaaaa aatagaaaag
    21841 ctgtaaaaag tcttttaaaa ggctttttgc agcttgattt ttaaaaaaat gtttatgaat
    21901 aaaaaaagtt gttcccggat ttcccagaaa aggtggtaga aagtggggga ttgtggtaga
    21961 ctaattttag ttagtggagg aatggggggc tttcaatgtt gatgggtgaa ttccaacata
    22021 atattgatgc aaaaggacgt ttaatcgtgc cctcaaaact tcgtgaagaa cttggcgaaa
    22081 agtttgttct gacacgcgga ttggatggct gtcttttcgg ctatccgatg agcgaatggg
    22141 aaaatctgga agctaaactg aacgaaatgc cgttggctaa aaaagacgca cgtacttttg
    22201 tgcgattctt ctattcggct gccactgaat gcgaacttga taaacaagga cgaatcaata
    22261 tacccagcac gttaagaaat tatgcagctt tgacaaaagg ttgcgtagtc atcggtgtat
    22321 ctaaccgaat tgaaatttgg gatgagacac gatggcaaga tttttctgca gcagcagaag
    22381 agaactttga cgaaattgct gaaagtatga ttgatttcgg actataagaa taggaagagg
    22441 ctgactaatg actgaaacat ttcaacacta tacagtcatg ttgaaagaaa cggtagatgg
    22501 attgaacatc aaaccggatg gcgtttatgt agactgtaca ctcggcggtg ccggacatag
    22561 tgaatattta ttaagccaac taagttctaa agggcatctg tatgcgtttg accaagatca
    22621 aaaagcaatc gatcacgcca agctgcgttt agcttcttat gtcgaacaag gtatggtcac
    22681 atttatcaaa gcgaacttca gagaattaga agaacgcttg agtgagcatg tagataaggt
    22741 agacggcatt ttgtatgatc taggggtttc ctctcctcag ctagatgaag cagaacgtgg
    22801 atttagttat catcaagatg caccgttgga tatgcgcatg gatcagtcag ctcctttatc
    22861 cgcttatcac gtaattaatg aatattccta ccatgaatta gtaaagattt tcttccgcta
    22921 tggcgaggag aaattttcca aacaaattgc tcgtgaaatc gaacgagtac gaaaaacaaa
    22981 accaatccaa acaactggtg agcttgtcga aatcattaaa caagtcatcc cagctcccgc
    23041 aagaagaaaa ggcgggcatc ctgcaaaaag aatttttcaa gctgtgcgga ttgcagtaaa
    23101 tgacgaactc ggtgccgaag aggcctcttt agaacaggca atccggttat tgaaagtcaa
    23161 tggaagaatc agcgtaatca cattccattc attggaagac agaattgtca aaagtatgtt
    23221 taaagaatat agtacggtac aagatctacc accgggactt cctgtcatac ctgacgaatt
    23281 ccaaccagaa ctgaaagtca ttactcgtaa accaatcctt ccttcagagg aagagctaac
    23341 agaaaacaat cgatcacgca gtgcaaagtt acgtattgca gaaaaaataa gaatgaaaga
    23401 ggagtagaat gatggcagaa ttaaagaaaa tgcaagatta cgaatatgat ttacctgaat
    23461 tggtggatca gccggaacaa caaatgcctg attcttcttc gaatcaagaa atcattcttc
    23521 cacaatcacc ggcaaaacga ttaaagcaga tttctgcttt ggaaaaaatt gctgtggcaa
    23581 gcgtggcgat tgctattgtt gctttatgtg ttttaacagt tatgctgcgc acaaatatca
    23641 gcggagctga aaaagaaatc acgtcaatac aaacagaaat caatgataaa aagcaagaaa
    23701 aaacgagttt agaacaagaa aaaaacgaac tttctcgtac tgaacggatt aaacaaatcg
    23761 cagaagaaaa aggattgtct attaatgacg acaatttaag gaaagtgaag taaatgagtc
    23821 ttaaaaataa aattcggcgg tttatggaaa agaaaaatct aaatccgatg aacaatcgca
    23881 aaaaagtagg tatcatttta tttgctacga gtattggatt gttcttttta tttgccgtcc
    23941 gtttctcgta tatcgttatt ggaggtcatg ttgctggtac ctcattagct gaaaaaacaa
    24001 aacagttgta ccaaggaagt gaagtagtaa aagcaaaaag aggaacgatt tatgatcgta
    24061 acggtgtggc gctcgcagaa gatgcctcct cttattcaat taaagcgata ctctcaaaaa
    24121 catatacctc tggggataaa aaactgtatg ttgaagaaaa gaattttgat aaaatagcag
    24181 aaatcctgca taagaatctt tctatagaca aaaaagatgc actgaatatt ttagaggacg
    24241 gcgcaaaaaa agagctgtat caagttgaat ttggtagcta tgggaaaaat atctcccaag
    24301 aaaccaagca aaacatcgaa gcggacatga aaaaagaagg tgtcgctggt ctttattttg
    24361 tcgaccatca ggctcggatg tatccaaatg gcgtcttttc ttctcatttt attggatacg
    24421 cagttccaga caaagatgag aatggcttag ttggtaaact aggtttggag tctgcttaca
    24481 atgatatctt gagcggtaaa gatggtaaga ttatttatca aaaagataat tttcaaaatc
    24541 ctctgccagg tacagtggca gaagaagaaa aagctgtcga cggacaagat atctacacga
    24601 ctttagacag cagactacaa agttatttag aaacactgat ggatcaagta aatgaagaat
    24661 atcagccaga agaattgaca gcagtcctga tgaaagcaaa aaccggagaa atcttggcaa
    24721 tgggacaacg acctactttc aatcctgaaa caatggaagg attgactgga aaagatgcta
    24781 tctggcgtaa tttcttggta caagatagtt atgaaccagg atcaaccatg aaagttttca
    24841 ctactgcagc tgctatcgaa gaaggagaat tcaacgagaa tgaaaccttc caatctggaa
    24901 aaatccaagt agaagatgct acgatcaatg accatgactt tggtgaaaaa ggtgtgctga
    24961 ccatgcgtca agctctttca tggtcaagta acgtcgggat ggtcatactg gaacagcgat
    25021 taggcggacg atggtataac tatttacaaa aactgggatt tggacaaagt actcattctg
    25081 gattagatga tgaagtaaac ggtgctttac ctacattaaa tattgtcgac cgagcaatga
    25141 gtgcttatgg acaagcggta ggtgtgacga atttccaaat gatgaaagct ttcacttcta
    25201 ttgcgaataa cggtacaatg attcaacctc gatatatcag caaagtggtg gatccccaaa
    25261 ctggagaaga gcgaacaact caaacagaag ttctagggca acctttttca aaagaaacaa
    25321 cagaaaaagt ccgtgaatat atgagagatg ttgtcgaaag cgaaaactac ggtagtgctt
    25381 atggtgtata tagtgtacct ggatacaatg tatcggcaaa aaacggaaca gcccaaatcg
    25441 cttctgatac agggggatat caaacaggag atacagccta cctgtattcg attgtggaga
    25501 tggttccttc tgaagatcca gactatgtct tgtatctaac aatgaaacac cctaagacat
    25561 atgatcgaat ggcattggct aaaatcgcaa atccattgat gaaacgggca atggatttta
    25621 aagaaactga agaagattca gatacagaaa caaaaacaga aaaagtatcc gtagccgatt
    25681 atcgtaatct tgaagcggac gttgcagcag ctgatgctca aaaaagtgga ctgcaacctg
    25741 tagtgatcgg taatggtaaa aaagtacaaa aacaatctac tgccaacggt gatcagttga
    25801 tctctggaga aaaactgatc ctatatactg gtggtgataa gctgatgcct gacgtaacag
    25861 gatggtcaaa agcagatatc atgaagctgg ggaaaatcct cggtattgaa gttagttttg
    25921 atggagatgg ttattgtgtc aaacaagaac ttgctccata tgaaaaaatc actgaagaca
    25981 aacttagttt tactttagaa gaataagaag agaaatagga gagaaaagag catggaatgg
    26041 acacaagcat tgattcccat tgtcagcagt tgtgcaatga caattgccgc aatgccgcta
    26101 tttattggtt attttcaaat gaaaaagcaa ggtcaggcga ttcgtgagga gggaccaaag
    26161 tggcacaata gcaaagccgg aactcctaca atgggcggct tagtgtttct gatcggctct
    26221 attttgacag gaatttgggt tggagcttgg caaaaacagc taactcctac tcttttcatc
    26281 ttgctttttg tattagcgtt atacggagta atcggctttc ttgatgattt tataaaaata
    26341 ttcaagaaaa gaaacatggg actgaactcg aagcagaaat tgattggaca gattctaggg
    26401 ggaatcatct tttatcttgt ttaccgttct gaaggttatc caggtgtatt gaatttcttc
    26461 ggactagatc tacctttagg aatcatttat ggtattttcg ctctcttctg gcttgttgga
    26521 ttttcaaatg cagtaaatct gacagatggc atcgatggat tagttgctgg cttaggaagt
    26581 atctcttttg cagcttacgg tctaattgct tggcatcagc atcagtatga tgtattaatc
    26641 atttgcttaa gtgttttagg aggtttactg ggtttcttcg tctacaacag aaaacctgcc
    26701 aagattttta tgggagatgt cggttcatta gcgttgggcg gacttttagc ggcaatttct
    26761 ataatgctaa accaagaatg gacattgctt ttgattggtt tgatctatgt tatggaaaca
    26821 gcaagtgtga tgcttcaagt tacttccttt aagcttacag gaaaacgaat ttttaaaatg
    26881 tctccaattc atcatcactt tgaaatgtgc ggatggtcgg agtggaagat tgatacagtt
    26941 ttttggttga tcagcattgt gacttcgttg atcacattat ggatcgtttg gtaggagatg
    27001 acgggaaatg aaaaaaatat caacatatga aaataagaaa gtgcttgtct taggactcgc
    27061 aaaaagcgga gtaagtgcgg ccaaattatt acatgaattg ggcgcacttg tcaccgttaa
    27121 tgatggaaaa ccttttgacg aaaatccgga agcacaagag ctgctttctt tagggataaa
    27181 agtaataaca ggtagtcatc caatcgaatt gttggatgaa gaattttcat tgatggtcaa
    27241 aaatccaggg attccctaca gtcatccttt agtagcaaaa gcccaagaaa tgggtattcc
    27301 ggtaattacg gaagttgagc tagcttacga agtagcggaa tgcccaatta ttgggattac
    27361 aggaacgaac ggaaaaacaa cgacaacaac gatgacagga ctactactga atgcaggagc
    27421 agatcaagga attgcacgtt tagcgggtaa tattgggtat ccagcaagtg gtgtagcgca
    27481 agaagcaaaa tcagaagata aaattgtgat ggaattgtct agcttccaac tcatgggaat
    27541 cacagatttc cgccctcata tagcggtgat taccaatatc tatgaagcac atattgatta
    27601 tcatggtaca agaaaagaat atgtcaaagc taaatggaac cttcaaaaaa acatgacaga
    27661 aaaagattat ctgatcctta actggaatca gtcagaacta caagaattag cgcaaagaac
    27721 aaaagcacgc gtactgcctt tctcgacaaa agaagtgttg gaagacggtg tgtatgctga
    27781 cgattactca atatactata aaaaagaaaa aataatggaa atatctgaac ttggcgtacc
    27841 aggtaagcat aatgtagaaa atgcactagc tgctatttct gtagcaaaat tgtatggtat
    27901 atcaaatgaa gctatacgag aaacgttgca ttttttccat ggcgtaccac atcgtacgca
    27961 atatgtagga gaaatccaag gcagaaaatt ttataatgat tcaaaagcaa ccaatatttt
    28021 agcgactaaa atggctctaa gtggatttga aacgtctaag gtcgtgttat tggctggcgg
    28081 attagacaga ggaaatacat ttgatgaatt aattccttca ttaaaaggaa tcaaagcaat
    28141 ggtcgtattt ggccaaacaa aagaaaagtt gatggatgct ggaaaaaaag caggcatcga
    28201 gacaatagta acagccgatt ctgtagaaca agcagttcct ttagcattag aaaacagtac
    28261 agatggtgat gtagttttat tatcaccagc gaatgccagc tgggatcaat acccaaattt
    28321 tgaaactaga ggaaacagat tcatggaagc tgtgaaccga ttaaaataga aaaagtagaa
    28381 gcgagcgata aaaaatgaaa attttggtta caggcggagg aacaggggga catatttatc
    28441 cagctcttgc ctttgtcaat tatgtaaaga ctcaagaacc gaatgctgaa ttcatgtatg
    28501 tgggagcaaa acgaggtcta gaaaacaaaa tcgtccctga tacaggaatg cctttccata
    28561 ccttggagat tcaaggattt aaacgaaaaa tttccatgca taacatcaag acggtccgat
    28621 tgtttcttaa gagtatccgt caagcaaaaa aaatcctcag tgattttcaa ccagatatcg
    28681 ttatcggtac tggaggatat gtttccggag cggtagtgta cgctgcagcc aaaatgggta
    28741 ttccaacagt tatccatgaa caaaacagtg taccaggtgt taccaataaa tttttaagcc
    28801 gatatgtgga tcggatcgct ctttcattta aagatgcggc ttcctttttt cctgaaaaca
    28861 aagcagttct tgtaggtaat cctcgagcac aagaagtagc agatactaaa aaatcagata
    28921 ttttgaaaac atttgatttg gatccagaaa agaaaacagt cttgattttt ggcggtagtc
    28981 aaggagcact taaaatcaat caagcagtat cagttttttt aagtgaatat attccttctt
    29041 cttaccaagt tttgtatgct tcaggagata gatattatga agagatccta aataaaataa
    29101 atcctgaaat acaaaatatt agtgtccagc cttatatcaa aaatatggca gaggtcatgg
    29161 cttccagtga tctgctggtg gggcgtgctg gtgcaacttc gatcgcagaa ttcacagctc
    29221 tggggttacc ggcagtgttg gttcccagcc catatgttac gaatgatcat cagactaaaa
    29281 atgcaatgag tcttgttcac gcaggagcag caaaaatgat tgcagataat gaactaacag
    29341 gtgaatcact aagtcagaca gtcaacgaaa tcatgggtga tgaagaattg caaaagcaaa
    29401 tgtgccgagc ttctaaagaa caaggaatcc ctgatgcttc aaaacgtctt tatgacttag
    29461 taaaacaaat aatcaaaaaa taaaggcggt ggtcttagtg agtaagaaaa aagaaccaaa
    29521 aaaattgtct catccgtctt ctgatgaaaa caatttgact ccttggcaaa aggctaaccg
    29581 aaaatatctg gcagaacaag agatgaaaaa ccaagagcca aaaaaagaag acataacatt
    29641 agatacaccc ctttcagatt ctgaagaaga aaaaacggtt caagaggaac agcaagaaga
    29701 aagccagtcc gagaaaaaaa tcgaattttt tgaagagatc aagcaaaaga aaaacggtgg
    29761 accatataac ggttcttttt tgaaccggct gcccaattta aaaagtcaac ggcacaaagt
    29821 actatttcgt cggttagctt tgatcatcac tgtattgggt ataccgctga tttttttgat
    29881 ctattatgtt tctccttata gcaaattaca agcagttgca gtatcaggca ataagacagt
    29941 caacagccaa gaaatcatct ctgatacaaa attgtcatta ggagaaaatg tttggggaca
    30001 gtattttcat cgatctactt atatcgatcg ccttaaaaaa gcacagccaa gaatcgaaac
    30061 agcaaatata catttcaaag ggatgaatga attcgatttg gatgtaacag aatataaaga
    30121 gattgctttg atcgcaaaaa acaatcaata ctacccagtg attgaaaatg gaacagtatt
    30181 agatgaaaaa gtagcaaatc ctacaaaaaa tctccctatc ttggaagagt tcaaagactc
    30241 tgcaaaaatc aaagaattaa caaagcaata caatcagtta tcatcagaat tacaaaaagc
    30301 aatttctgaa atcaagtaca cgccaagagc aagcaataaa aatctgatcc aattgaatat
    30361 gaatgacggc aatcaagtta ttgtaaatat caataatctt gcgaaccaaa tgaaatatta
    30421 ttcgcaagta gccaaagata tggatgaaaa aggtgtgatc gacatggaag ttggtatctt
    30481 ctcgcatcct tacggtagca ctcaagaaac ggaagaatcg ggccaatcgg aagaaacaac
    30541 tgaaagtgaa gaaaatgcgg atcaaacaaa cgaatcaagt gaagaggcag aaacgcaaaa
    30601 agcacaaaca cctggatcgt ctagcacaaa cggatcatct gattcaaatg attcaagtga
    30661 aacaagtcaa atagaagata atccaagtac aactccgtca agtttaaatg aaaattgata
    30721 aaacaacttt aaaaagtaag aatgtacttt ctaaaaacca gtaatttatg gtagaattgg
    30781 aagcagtgaa tatatctatt aataagtata ttttaaaacg gacgctagtt gttcgcttgt
    30841 atatggaata gtaagtagga gggaatccca ttcatggcaa aaacaggaat gtatgtaggc
    30901 cttgatattg gaacgacatc tgttaaagtt gtcgtggctg aatatatcga cagccaaatg
    30961 aatattattg gagtaggaaa cgcaaaatca gaagggatta accgaggcat tatcgttgat
    31021 atcgataaaa cggtccaagc gatacaacga gcagtacgac aagcagaaga aaaagcaggt
    31081 atccagatca aaggcgtaag tgtcggtttg ccagcaaaca tgcttgaagt agaaaattgc
    31141 cagggaatga ttgcagttaa cggagattca aaggaaatca ccgatgaaga tgtcagaaat
    31201 gtggcttcag ctgcccttgt tcgttcaata cctcctgaac gtcaaatcgt gtcaatattg
    31261 ccacaagatt ttactgtcga tgggttcgag ggaatcaaag atcctcgtgg aatgatcggc
    31321 gtaagattag aaatgtacgg tctgttgttt acaggaccta aaacgatcat ccataacata
    31381 cgtaaatgcg tggaaaatgc cggattaatc gtcaacgaaa tggtgattac tcctttagcg
    31441 ctgactgaat caattctttc tgacggagaa aaagattttg gtacgatcgt cattgatatg
    31501 ggtggcggcc aaacaacaac ggctgttatg catgataagc aattgaagtt taccaatctt
    31561 gaccaagaag gtggcgaatt tgtcactaaa gatatctcta ttgtattaaa tacgtcattt
    31621 aacaatgcag aagcgttgaa aataaactac ggggatgcat acccagaacg gacatcacca
    31681 gatgaagaat ttccagtaga tgtgattggt cagtcagaac cagtgaaagt cgatgaacgc
    31741 tacttgtcag aaattatttc agctcgaatg gaacagattt tcaacaaagc aaaagatgca
    31801 ttggaccaaa tcgaagcatt agagttgcca ggtggcgtcg tattgacagg cggagctgct
    31861 agtcttcctg gtgttgtgga cttggcacaa gaaatcttcg gcgtaaatgt aaaattgtat
    31921 gttccaaatc acatggggct gagaaacccg gtatttacaa atgtaataag tatcgtggat
    31981 tattcagcaa acttgagtga agtgtatcaa ttggcaaaaa ttgctgttac gggtgaaacc
    32041 tcagcagctc gtcaaatggt agttgaacaa gaaacaacaa acacatatga gagctatgaa
    32101 gcacctgaag aaacaatcta cgatgagccg gaaccaaaag agtccggaga aaatgtaaaa
    32161 aataaaatca agggtttctt tacaaatatt tttgattaat tcatcctggg aggaataaga
    32221 tatggaattc tcaattgata ataatatcaa tgacggcgca gtaatcaaag tcatcggagt
    32281 cggtggtggc ggtggaaatg ctgtaaaccg aatgattgaa gaaaacgtta aaggtgttga
    32341 attcattaca gccaacacag acgtgcaagc attaaaaaat tcaaaagctg aaacagttat
    32401 ccaattaggc cccaaatata ctcgtggttt aggtgctggt tctcagccag aagttggaca
    32461 aaaagcggca gaagaaagtg aacaatcctt acgcgaagct ttagacggtg cagatatgat
    32521 tttcatcact gcaggaatgg gtggaggaac cggtacaggt gctgcaccaa tcgttgcagg
    32581 tatcgcgaaa gaattgggcg cattgactgt tggtgtcgtg acacgtccat tcacttttga
    32641 aggaccgaaa cgtggccgtt ttgctgcaga aggtatcgct cgtttgaaag aaaatgtgga
    32701 tacattatta attatctcaa ataaccgttt attagaagtt gtagataaaa agacaccgat
    32761 gcttgaagct ttccgtgaag cagataatgt tttacgacaa ggtgtacaag gtatctctga
    32821 tttgatcaca gcgccaggtt acgttaacct tgactttgct gacgtgaaaa cagtgatgga
    32881 aaaccaaggt acagcattga tggggatcgg tgtggctagt ggagaagatc gcgtagtaga
    32941 agcaacgaaa aaagcaatct cctctccatt gcttgaaaca tctattgatg gagctgaaca
    33001 agtacttctt aacatcacag gcggtttgga tatgacattg ttcgaagcac aagatgcttc
    33061 agatatcgta gcaaatgcag caactggcga tgtaaatatc attctaggta catctatcaa
    33121 tgaagaaatg ggcgatgaaa tccgtgtgac ggtcatcgca acaggtatcg atgaatcaaa
    33181 aaaggaacgc aagtctagcc gaccagctag acaagcacaa atgcaatcac ctgctcaaaa
    33241 gactgtatta gatatggatc aagctaaacc aacttcttca gaagaagaaa acagttttgg
    33301 cgattgggat atcagacgtg aacaaaatgt tcgtcctaga gttgatgatt ccaattttga
    33361 caatatcgaa aaaaaagaat ttgatacatt caaccgcgaa gaaacaaaat ctcatggcga
    33421 tgatgaatta aatacgccac cgtttttccg tcgtaaaaaa taaaggagag gaagagcaca
    33481 tgattgctga caacttgcag aaaatcaagc aagaaattca ggattcgtgt gctcttgttc
    33541 atcgtgatcc gaaagaagtt acattagtag ctgtaacaaa atctgttgaa tccgctcaag
    33601 ctgaagaatt ggttagagct ggcgttatga attgtgcaga aaaccgagta gataaattat
    33661 tagaaaagaa acaagattta tttgattttc ctgaaataaa gtggcattta attggtaatt
    33721 tacagcgcag aaaggtaaaa ttgattgtaa atgaaattga ttactttcat gcgttggaca
    33781 gtttaagatt agcagaagaa atccagaagc ggttagagaa agaattatcc tgttttattg
    33841 aagtaaatgt ttctggtgag gaatcaaaac atggaatttc accagatgag cttttaccgt
    33901 ttgtggaatc tttagctgcc tgcacaaaaa tcaaggttgt tgggttgatg actatggcgc
    33961 ctaaagaagc ttctgatgag caaatccata aagtgtttgg tacgctgaaa gaattgcgtg
    34021 atcttgttca agcaaaaggt tatgcccatg caccatgtag tgaattaagt atggggatga
    34081 gtcaagactt tcaaattgcg attgaagaag gtgcaacatt tatccgtgta ggaacagcgc
    34141 tattcaaaga cgaataaagg aggaacaaaa atgccgcttt taaacagagg agcaattgct
    34201 aattttttcg gattagctga tgaggaagag tacgaatacc aagattatcc tgaaacaaca
    34261 aaaaaggctg tacagccaac taaaaaaaat acaacacaga atcaatcaac tcattctgta
    34321 tctgctgcga atactcatga aaaacaaaaa acggcgactt cacgtcctgt aacgcatgaa
    34381 agtattcagc cggctgaaaa gaaaaaagta attgaactac atcaatcacc tacaaaaact
    34441 gtagcgaaag aaagaacagc ttcaagaacc tctacacaac ctaaagcaaa tcttgctgga
    34501 aaaatcactg taatggaacc aagagcttat tctgaagcta tggcgattgc taaacgaatc
    34561 attgctggag aagcaacctt agtgaatttt catttagtag aagaaaaaca agcgagaaga
    34621 atcgttgatt ttctaacagg aacagtttat gcactagatg gagatatcaa acgtgttgga
    34681 gatgagattt ttctttgtac accgactggg atggagattg acagttcaac cgctcaatct
    34741 tttgcagatg cgaatttgtt tgatctgtaa gaggaggaac tacgatttat actattgcac
    34801 tattacttca tttacttcaa cgggcagcct atttctatag cattatcttg atggtatatg
    34861 cattgctctc ttggtttcca ggcgggtatc aatcagggct aggacgatta ttagctaaga
    34921 tctgcgaacc gtatatcagt ttgttcgatc gtctgccttt gaggattgga cccttggatt
    34981 tcacaatttt aggggcaatc ctgatcttga acttagccgt acaaggttta gcacagatcg
    35041 ttatatggat aactgtccat ttagtttatt gattgaagca acaaaatctt tattctcaga
    35101 atagatagga ggggaaaatt ttggatgcaa atgtatacca gcactttcgg gcagatgaac
    35161 gtacatttat cgattcggta ggcgattgga ttgaacaggt tcaaggacaa tatgcaccct
    35221 atctgaccga atttcttgac ccaagacaat cctatatttt agaaacactg attcgacaaa
    35281 gcagtgattt gcgtttcatg ttttatggcg gatatgaaca ggcagaaaga aaaagatgtt
    35341 tgattttccc cgattattac gaacctgtag aggaagattt tgaaacagca ttgtatgaaa
    35401 tccattatcc tagcaaattt gccagcctaa gtcatgggaa aatccttgga actttagtgg
    35461 gaacggggat caaacgctct tactttggcg atatcatctc ggacggtgat cgctggcaag
    35521 tatttattgc aaatgaggtg gatcattttg ttgctgcaca agtaacaaag attggaaagg
    35581 ttgctgtacg cttggaacca atcaaataca cagaaatgat tatgccgaaa gatagctgga
    35641 cacaagaaag aggaacagtt agttccatgc gactagacag tgtgatctct gagatttata
    35701 atatttccag acagcggtcc aagcagctga tcgaagctgg taaagtaaaa gtgaactgga
    35761 cagaaaatac aagacctgat tttgtacttg aactattaga tattatttca gtcagaggtt
    35821 atggcagagt ccagatccaa gaacttgagg ggaagacgaa aaaagaaaag tacagggtac
    35881 tgttcggtgt attacgtaaa taaaataaaa aggtggttta ctcatggctt taactccatt
    35941 agatatccaa aataagacat tcccgacaaa aatgcgggga tataatcaag acgaagtaga
    36001 tgatttctta gatttagttg ttcgtgacta tgaggaattg actcaaagaa atcgagaatt
    36061 agaaaaagca gtcaaacatt ctgaagaaaa acttgagtac ttcaatgaat taaaagatgc
    36121 tttgaaccaa tcaatcatcg tagctcaaga tacggctgat aaagtaaaaa caagtgcaag
    36181 caaggaatcc gaagtgatcg ttacttctgc acaaaacaaa gcagatgagt tagttgcgaa
    36241 cgctgaaaaa cgtgcacatc aattaacaac tgatgcagaa gaaaaagcaa gaaaaatctt
    36301 gacagatgca acagaaaaag caagacagct tgcgacagaa actgaagatc ttaagaaaaa
    36361 aacacgagta ttccatcaac gtatcagctt gatgcttgag tctcaattag aacaagtgaa
    36421 aagtccggaa tgggatgaaa ttttacaacc attctccagc tacgtgactg acagccatga
    36481 agtgatcaaa gaagttttag caaaacagct tgacaatgaa aatgatactg atgtaaactc
    36541 agacacagga gtcatagaag cacctatgac ggcatttgat acacaggcta ttgatatctc
    36601 gatcgtgcct ggtgaaaatg aaaacgagta gaacagaaaa gcactttgtt attcttaaag
    36661 cgagccgatg agagtggaag ttcggtaaga cactgcatgg tgaaagatcc tctacttgag
    36721 acctgctttt ccgaaattag agtaagaagc agcggctgac ctcgttattg gtcacagaga
    36781 gtttgcacta gatagatgca actaaatttg ggtggtacca cggcatgttc gtcccttgcg
    36841 gctgaacatg cttttttgtg tccggaaaac aaataaagga gtgtatggtt gaatgaaaat
    36901 gaaagaaacc ttgcaattag gaaaaacaaa attccctatg cgtggtaatt tgccaaaccg
    36961 agaaggcgag tggcaaaaag aatgggaaga aaatcgaatc taccaaaaaa gacaagagtt
    37021 gaacgaagga aaacctagct ttgttcttca tgatggacct ccatatgcca atggtaatat
    37081 ccatttagga cattcattga ataaaatcag taaagacatt atcattcgtt caaaatcaat
    37141 gtctggctat cgtgcaccat atgttccagg atgggataca catggattgc cgattgaaca
    37201 agtattggct aataaaggcg tgaaacgtaa agaaatgtcc atggcagaat acttggaaaa
    37261 atgtcgtgaa tatgcacttt cccaagtaga taagcaacga gcagatttca aacgcctagg
    37321 agttgcagga gattgggaac atccttatgt tacattagat ccttcttatg aagctgcaca
    37381 agtacgcgta tttggtaaaa tggctgaaaa aggctatatt tacaaaggat tgaaaccaat
    37441 ttactggtct ccgtcaagtg agtcttcttt agcggaagct gaaattgaat ataaagatgt
    37501 aaaatctcca tctatttttg tagctttcaa tgtcaaagac ggcaaagata ttcttgatga
    37561 agatacagct tttgtcattt ggacgacaac accatggaca ttgccagcaa accaaggtat
    37621 tgctgtaaat ccaaaattta cgtatgtatt ggtggaagcc gatggccgta agtttgtcgt
    37681 agcgaaagat ttgctagaaa cagtccaatc agaaatcggt tgggaaaatg taacagttct
    37741 aaaagaattt gctggacaag aaatggaata tatgactgca agtcatccat tctatgaacg
    37801 tgaatcactt gtgattttag gcgatcatgt tactttagac gctggtactg gattagtcca
    37861 tactgctcca ggacatgggg aagatgacta tatcgctggt agcaaatata aactatctgt
    37921 agtgtcacct gtagactcaa aaggattgtt tacagaagaa gcacctggat ttgaaggtat
    37981 cttttatgac aaagcaaatc ctatgatcac tgatctatta aaagaaaaag gagctttgct
    38041 gaagctagat ttctttactc atagttatcc tcacgattgg cggacgaaaa agcctgtgat
    38101 ctatcgggca actccacaat ggtttgcatc tatcgataaa ttccgtcaga atattttgga
    38161 tgaagtagaa aaagtagagt gggttatccc atggggtaaa acacgtttgt ataatatgat
    38221 ccgtgaccgc ggcgattggg taatttcccg tcagcgtgca tggggagtac cacttccgat
    38281 tttctatgct gaaaatggag aagcaatcat cacaccagaa acaatcgaac atgtggcaaa
    38341 attatttgct gaacatggat caattatctg gtttgaaaaa gaagcgaaag aacttcttcc
    38401 tgaaggattt acccacccag gttctcctaa tggcgaattt acaaaagaaa aagatatcat
    38461 ggatgtctgg tttgattctg gttcttctca tgaagctgtt ttacgtcagc gaccagaatt
    38521 atcattccca gcagatatgt atttagaagg atcagaccaa tatcgtggct ggttcaactc
    38581 aagtatcacg actagtgtgg ctatcaatgg tgtagcacca tacaaatcag ttatttctca
    38641 aggatttgct ttagatggtg aaggccgtaa gatgagtaaa tctttaggaa acatcattgc
    38701 accagaaaaa gtgatcaaac aatttggtgc agatatcctt cgcttatggg tatctagtgt
    38761 agattatgaa gcagatgttc gtgtttctat ggatatctta agtcaagtgg cagaagtata
    38821 tcgtaaaatc agaaatacga tgcgtttctt attagcgaat acagaagatt tcgatcctaa
    38881 aaaagatact gtttcgtaca atgatttacg ttctgtagac aaatatatga ccgttcgatt
    38941 gaaccaagta atcaaagaaa tccgagaaga agggtacgac aaatataact tcatgcatat
    39001 ttaccgtaca gttatgaact tcttgacggt tgatctatcg tcattctacc tggattttgc
    39061 taaagatgta gtttatattg aagcagaaga tgattatcaa cgtcgttgca tgcaaactgt
    39121 tttctatcaa acagctgtag ctttgacaaa attattgact cctatcattc cgcatacagc
    39181 agaagaaatc tggtcattcc tgaaagaaga agaggagtac gttcagttaa gcgagtttcc
    39241 tggttatgaa gagtttgcaa accaagaaga attgatggat acctggactg ctttcatgga
    39301 cttccgtgat aatgtcttaa aagcattgga agaagcaaga aacagcaaat tgattggtaa
    39361 atctttggaa gcaaaactaa ctgtttatcc aaaacaacaa gttcgtgaaa tgttaaaagc
    39421 tttggatgca gatattgcac aattattgat cgtttcacca gactactttg aagttatggc
    39481 agcagatgaa caagtgccag ataacgctat ggtatttgat gatgttgcta ttacagtgga
    39541 aaaagcagac ggggaaactt gcgatcgctg tcgccaagtt cgtaaagatg taggagtaga
    39601 tgaaaaactt cctcatctat gcggtcgttg tgcaaaaatc gttgaagact tctatcctga
    39661 agctgtagct gaaggattcg aagaaaagta aaagggaaaa gggggtgtga catgttcttt
    39721 gtcacacccc cttttgttat caatcgttta attttccacg ttcacgatac cagttatctg
    39781 gttgccagat ccattcgaat ccgtcttttt caagtagttc gaaagctgct ttaggtccca
    39841 ttgatccagc tttgtagttg ggaaaatccg gttgtgtttg gtcccaagct tttcgaatga
    39901 catccacgat atgccaagat tgagcgactt cttcccaatg agagaagttc gttccatcac
    39961 cattcaacgc atctaatagt aatttttcgt aagcttctgg gctattttca accatttctg
    40021 cactatttct aaattccaat ttgattggtt ccgtttcaaa tccttgccct acttctttcc
    40081 cattcaagga taaagaaaat ccttcagttg gctgaatata gatcgttaga acattaggtg
    40141 gaagtgtcgt atcgtcacat ggttcatcga cagatgtttt gaatacatta acaggaactt
    40201 gtttgaatac gatgttgatc cgagtccctt tttcagtcaa acgtttgcct gtacgtacat
    40261 agaaaggaac acctgaccaa cggaagttat cgatagtgaa tttgcctgcg acgaatgttt
    40321 cagtctctga ttgagcatcc actttgtctt cttcgcgata gcccttgaat tgtacaccat
    40381 ccaattcacc ttgagcatat tgcccgcgaa cgaagttttc taacacttct tcttcgttat
    40441 aaatgcggat agctttcaat gctttgatct tttctgtacg gatttctttt tcggaaaatg
    40501 ctactggcgg ttccattgca agtaatgcta caacctgtaa aatatgattt tgcaccatgt
    40561 ctttaagtgc gccactatga tcgtagtagc ccccgcgatc ttctacaccg aggttttcgc
    40621 caaaagtaat ttggatattg tcgatatagc gattgttcca ttgagcctca aaaatattat
    40681 tggcaaaacg gatagctgag atgttttgga tcatttcttt tcctaaataa tgatcaatcc
    40741 tgaaaatatc ttgttctggg aatacttctc tgatttgctg gttcaattca aaagcagact
    40801 ggtaatcaga accgaacggt ttttctatga tcaaacgatt gaagccattt tttgtcataa
    40861 tattttgtga tttcaaatga gaaacgatcg ttccaaaaaa ttgaggtgcc atagccaaat
    40921 aatagacacg gttaccgttt aattgatagt gtccatctaa tcggtcagac aattctttta
    40981 atgtctgata atgcgttgaa tcatttacat catgggattg atagtaaaaa tggcttgcaa
    41041 aggtagttgc ttcttcatct gaaggattca atgcacggat tgtttctttg acaacttcac
    41101 ggtagtgctc atcgctccag ggacggcgag cggttccgat tacagcaaaa tgctcgccta
    41161 aatttccttt tctgtaaagg cggaacaaag acgggtacaa tttacgctgg gctaggtcac
    41221 ctgtaccgcc gaatatcgta aacaatacat ttttttcatt agacatgtgg atacactcct
    41281 ttatatttta tcgacaaaaa tcgtgctggc cgccttaaag ctgacgggga ttttctttct
    41341 atcattttgg atagtgatcg gtccttcata agctgcgatg tcaacgatct catattcttc
    41401 gttgatattc aggtcaatag tgactaagta atccaacaat tctttttcat caagcactcg
    41461 tgcgatacgc acttttgtac cgacaggata ggactccaat gtttgtcggc gttcttcatg
    41521 gacaacttcc tcttttttag gaatcgatcc tccatgagga caatgttcag gatgattcaa
    41581 atagttttct aaatgatctg caagatgttc cgaagtcaca tgttccaata cttcagcatc
    41641 atcatggact tcattccagc tatagtctaa atgttcaact aaaaaaactt cccataagcg
    41701 atgtttgcga atcagactgc tagctttttg cagtccgctt gcagtcaatt gtacaccttg
    41761 ataaggggaa tgttctacaa gctcttcttt cacaagttta gaaatcattt cactgacaga
    41821 tgcagctgag acatctagac tagatacgat ttgtttattg ttgactttcg ttgtatctcc
    41881 acctagttct aaaatgattt tcaaataatc ttctcgattt ggtgtcatat tcgatcatcc
    41941 tttcatggta aaaaaccatc attagtaagt gtaacaaaaa aaacgttaat tgactatttt
    42001 tctaaataaa aaacaaagga tttttagacg tttttacaac aaaaaacgaa agatgataga
    42061 gaagactcat tctttcgttt ataaaggata tatatataca ttgggaggga tctatttttc
    42121 agataacaac ttatatgaag tgtctgcaga ttcgtcataa agagtttgtt cgggataaga
    42181 aaagataaga taaaaaccat actgatcacg tacgactaaa cgatattcat ctatttctac
    42241 cacagatgtg ccaagagact gaccgttgat caaaaacgtg taatcagatg taatctgtaa
    42301 ttgttgtttt tgctggctat cactaaagaa ccatgtacct tgatactttg agagtccttc
    42361 tgacttttcc gcttgttttt tctttttcaa gtaaataaaa cttgagagaa cggtaatgag
    42421 tgaaccaaga aaatagatca ttttttttat caccaaatca ctcctttatg agaaaataat
    42481 cgcatagaca tattctttct tctttatttc attgtaccga ataaaagcta aaatttctct
    42541 aagactttcg actggttttt ttactgtttt tctacaaatt atgataggat acatagtagg
    42601 aagaaaggtg acataatttg aagtatcagc aagtggaaat agcttttttt attgaccgcc
    42661 cgaatcggtt tatagcacat tgtatgaaaa aagacggaga aataattatt gcgcatgtca
    42721 aaaatacagg tagaggaaaa gaggtcctga taccaggcgc tgaagtggct attgtatttg
    42781 ctcctggacc taaacggaaa accgcctatg atctgattgc tgtaaaaaag aagggtgact
    42841 ggtttaatat cgatagtcaa ttgcctaatc ggctggcaat tgatggtatt ttagacggca
    42901 cgatcctttt accaggatta actggtccat ttacggtata caagcgtgaa gtaacttatc
    42961 ttcactccaa atttgatatt tatttagaga cggtggtcgg acaaaaagca tttgttgaag
    43021 tcaaaggtat gacacttgaa aataaagcga ttggtgcttt tcctgatgcg cccacactca
    43081 gaggattgaa acatatagga gaattaacgt atgccgcaca agatggttat gccgcttatg
    43141 tcttgtttat tgctcagttc gaacatcttc atctggcaac gatccatgaa gaaatgcaac
    43201 cagcactagc tgatatggtt cgacatgcgc agcaaagcgg agttcaaatc ctcgcctata
    43261 attgtcaagt atcggcagat gaggtaactg tcaagcaggc cattccattt gatgtagata
    43321 tcccttttga agatcctata caatagaaag aaggtaaaat aatgatcaac ttaggtatta
    43381 tcggaacaaa ttggattact catcaatttg tccaagcagc tttaagcaca aaaaaatatg
    43441 aattgacagc ggtatattct agacatttgg aaaaagcaca ggaatttggt tctcattatg
    43501 aaggggatat cgaattcgca acagatttga agactttttt caatattact catatggaca
    43561 ccatttatat tgcttctccg aatagtcttc actttagtca agctaagcaa gcaattttgg
    43621 caggaaaaaa tgtgatagtt gaaaagccag ctttttcgac gccaaaagaa atggatgaaa
    43681 tcatccattt ggcaaatgaa cacaatgtgt atttttttga agcagcaaga aatatccatg
    43741 aatcaggttt taaaaagatt gccgattact taccattaaa agacgagata atcggtgcaa
    43801 atttcagcta tatgaaatat tcttcgcgct atgaccaagt attagatgga gaagaaccga
    43861 atatcttctc gactcatttc tcaggtggtg cattgatgga tttaggtgtt taccttgtat
    43921 atgcagctgt tgcttggttt ggaatgccaa aagaagtcca ttatttccca agaaagattt
    43981 ctactggtgt agatggtctt ggatggggga tcttacgtta tgagaatttt gatgtatcga
    44041 tccagccagg taaaatcggt gattcttatt taccgtcaga gatttatttt gactcaggaa
    44101 cgctagtgat gaatggagtc aatgcaattg aacaagcaca atttcatgat cgcgcgcata
    44161 aagaaatcat tgatttggcg gtaacagctg cagaaaatcc aatggcagat gaagcagagg
    44221 attttgccaa tgtcatggct catccgaaag atccagcttg gggattgttg tatgaagagt
    44281 ggatcgagct agctagaaat gtgaaccaag tgatttatga tttaagaaaa aatggcggca
    44341 tcaaattcga tgcagataat gaggaagatt tttaatgaac gaatttgtac aagtatttcc
    44401 cgaaaattgg cagaaaaaat atgaggataa agggtttatc tcaccttctc ttattcaacg
    44461 agcagttttt cagccactaa gtaataaaca aagtatagta gcggtttctc ctacaggttc
    44521 aggtaaaaca ctggcttatc tttggcctct actactaaac gtggaaccag gtgaagcaag
    44581 tgcgttggtc atttttgctt cttctcaaga actagctatt caagtagcag atgttgcacg
    44641 tgaatgggga aaagacaaag agttgaaagt ccaatctttg gtgggcggag ccaacgtcaa
    44701 acgtcagatt gagggtttga aggaaaaacc agaaatcttg attggtacac caggaagaat
    44761 attggaattg atgaaagcaa aaaaaataaa agcacatcaa gtgaaaacaa tggtatttga
    44821 tgaagcagac cagctatttg acgctgggaa cagccaaatc attgatcaaa ttcttcatca
    44881 agctccaaca gagtatcagc tagctttttt ttcagcgaca gcagatcgtt cccttgaaag
    44941 cattgaaaaa atcactggga aaacgtttga gacaattgac gtgacagcag aggacgattc
    45001 tcgaaaagga ctgagacatt actttttacg tgtaccgata cgaaagaaag atgactactt
    45061 gagacgtctc acgcatatag aagattttca tggtctgatt ttctttaatc aactgactga
    45121 attaggcgta atggaagaaa aattgctgta tagaggtgta ccggtaggaa gtctggcctc
    45181 tgatcagaac aagctactcc gaaaagcagc gctagaacaa ttcaaaaaga aaatggtcag
    45241 agcacttttg accacagatg tggcggctag aggtttagat attacaggtc ttccttatgt
    45301 agtgaatgca gaagttccgt taagtgaaga agcttatttg catcgttcgg gaagaactgg
    45361 tcgaatgggt aatgaaggaa tagtaattac actcgtacaa gataataatc taagagattt
    45421 aaaacggctt ttacgtccat caaatataac acttgaagag atttttttat acggaggtaa
    45481 gctgcaaact gagcagccaa ccaaagaaga tgcagctcct gcagtaaata aaaagtatgc
    45541 gaaaactttt tctggaaagg agcagaaccc agaatataac aaagaaaaaa taagaaaaaa
    45601 agttaaaaat aaatcaaaaa aagagagaaa taaaggagca aggcgcaaat aagcgccttt
    45661 ttatgctatg attatgaaaa cgggaacaaa attggttgcc agaggagggg ttatgtgaaa
    45721 gaacgtcaag aagagatctt gcagctattg acagaaaacc aacaaggatt gacagcaagt
    45781 gatgtagctg agcgcttaac tatcgatcga agcaatgcaa gccgatattt aagtgaacta
    45841 tacaaggccc atcatattgt aaaaaccgct ggccgaccag tcgtttactc tttgccaacg
    45901 gaaaagtcaa aatctgatga agtgcatgtc gactcttcta cgcaagtgac ttttgaaaca
    45961 ctcgttggag aaaatgattc tttaaaagtc agcatacagc aggcaaaagc tgcgattctt
    46021 tatccaccgc gggggttgca tacgattatt tttggagaaa ctggtacagg gaagtcgatg
    46081 tttgctgaat gtatgtatca ttttgcaatc gattcagaga tgctttctgc agatgcgcca
    46141 tttgtttctt tcaattgtgc ggattatgct caaaatccgc aactgctctt tggacacatc
    46201 tttgggatca aaaaaggggc ttacacagga gcagctcaag atagtcccgg tctaatagcc
    46261 aaagcagacg gcggtatatt gtttttagat gagatccacc gtttaccgcc ggaagggcag
    46321 gaaatgctgt ttactttcat tgataaaggt atttaccgtc cgcttggaga aagtgcacaa
    46381 gtacatgaag catctgttca gatcattggg gcgacgactg aatcttcaga aagtttctta
    46441 tctacgttca atcgacggat tcctatggca atcaccttgc cgaatcttgc ttcacgttca
    46501 ctggatgagc gttatgaaat catctctctt tttatcaaac aagaagcgaa tcgtttgaat
    46561 caacgtatcg atatcgaaaa agaagcgatt cttgccttca tgctttatga tgcggaagga
    46621 aatatcggtc aagtgaaacg agacttgaaa ctagtctgtg caaaatcttt tttacattac
    46681 cgtactcatc atgagaaaaa gctaatcatt cgaaaagaag aactttccct tcaagtacaa
    46741 aaaggattac tgaaaatcaa ggaaataccg gaacgtctcg accgattcat ggacagcaaa
    46801 agtcagtatt tgacatttga accaggattt gctgatgttg tctggtcaca agatccagaa
    46861 cgaaacatgc aggtctataa cgatattgag gaaaaagtca cttctctttc cgaaaccggt
    46921 gtggagaaca ttgatctaga gaccctcatt tcaaaagatg tggatgctta tttccagaca
    46981 tatgtcaaag aattgactaa aagttcgatt cccaaagatc ttttgccaga tgaaatctgg
    47041 cggttaacca atcaattgta tgatgtggct gaaaaacggt tagaccgtat ttataatgaa
    47101 aaagctcgtt ttgcttttgc tttgcatctg caaagtacat tggatcgtgt gagagaaggt
    47161 catatgatcg tccacccaga tttgaataac gtacggaaaa attttaagag ggaattccag
    47221 gtagcaatcg atctttcaac gatcattgaa gaagaagaac aagttgagat tccttttgat
    47281 gaaatcggct ttattagtat gtttctttct atcaatctag gagaaagtga gcctgttaaa
    47341 gaaaacaaag tagatgttct catattgatg cacggcagac agactgcttc aagcatgttg
    47401 gagatggcac aagaactatt aggaacaaaa gtagggaaag cttttaatat gccactggtt
    47461 atggaagttc aaacaatgta tgaagaagtg ttacaatatg tcaaaaacta tcaagagcat
    47521 ttgacgaatg gcctactctt gttaacagat atgggatcat taaacacctt cagtgatttg
    47581 atttatgaag agactggcat tcggacgaaa gctatcacga tgacaagtac catgattgtg
    47641 atagaagcga tacggatggc aagtgttgga agaagcttag aagatattta tcaaaatatc
    47701 cagctttcct ttgaatcgat cgtacgtgat cagttcaaag cggaaaagtc tgaaacttta
    47761 cagcgtaaaa aagccgtaat cgtgacatgc tttactggtg aaggagtagc tgccaaatta
    47821 tatcagcgta ttatgccagt gattaatcaa aataaggtag aactgatcca gatgcagttt
    47881 ttagaacgtg aatcattcaa aaaacacatc gatgccttat tggaagaata tgagatcaaa
    47941 gcaattgcgg gaacagttga tgttgattat caaaatatcc catttttttc agcctatgac
    48001 gtttttgatg atgaaaaact aaatatttta aagcgtatag ctgatgatga gatcccgaca
    48061 gctaaaattg tcgattcact tgctggatca ttaagcgatg tcttttctat tgatgaactg
    48121 atccgttcat tgcaaaagac agttcagcag atccagaccg atttgtcgat tatcgtggaa
    48181 cctggagtag atactggaat cgttatccat ttagccttca tgttagacgg attgatcaaa
    48241 caagaaagcc atcggcaatt tgagaaactg tctattttct caaaaattta tcgtttggaa
    48301 atggatatcg ttcgggcaaa cttgatggca ctagaacgaa aatatcaggt aaaaattcca
    48361 gaagatgata tcgcatttct tacacaaatg tttcttgaaa ataaaataaa aaaatgaaca
    48421 cactaatcat actgtttaca cactaaacat ctgtgtgcgc actataaaaa agagctaaaa
    48481 agcatgaaaa cgctatttca gctctttttt ttattggcat gcttcttgcg ttatataaaa
    48541 gtgtaaaaaa ataaaaggag tgttaaaaat ggcaaaaaaa acaatcatgt tagtttgttc
    48601 agcagggatg agtacgagtt tattggtcac aaaaatgcaa aaagcagcag aagaaaaagg
    48661 gatggaagcc gatatttttg cggtctctgc ctcagatgca gataataatt tagaatctaa
    48721 gaatgtcgat gtattattat taggtcctca agtacgtttc atgaaagctc aatttgaaca
    48781 aaaacttgcg cctaaaggta ttccattaga tgtcatcaat atgcaagact atggcatgat
    48841 gaacggagaa aaagttcttg cacaagcaga aaatctaatg aaataaatca agtatgcagt
    48901 tgggggtata acaacgtgga agatcaacaa aatctagaag ccatcatggg gttaatcatg
    48961 tttggcggta atgcaaagag cgatgcaatg gaagcgattg cggctgctaa aatcggtgat
    49021 tttgagttag cggataggaa aatcgctgat gcagaagaat cacttataca agcgcatcat
    49081 gcacaaacag acatgttgac acaagaagca caaggaaatc atatgcaagt gacattattg
    49141 actgttcaca gtcaagatca cttaatgaca tctattgcgt ttactgattt agcaaaagaa
    49201 atcatcgaac tttatcgtcg cgtatacagc gaataaatac aacttctttt ttgaacggaa
    49261 gaagaaaaat ttttgaacgg attttttatt ttgttataag gagaactctc tttatataaa
    49321 aaacttatag gaggaagtaa aaaatgaacg gactatcaag ttggatggag aaatacatcc
    49381 tgccggttgc cgcaaaaatc ggagcgcaaa aacatttagt tgctttgcgt gatgctttta
    49441 tcggcatact gcccgcaaca atggcgggat cagtcgctgt aatgatcaat gcaattattc
    49501 gtgatttacc gcaacagttt aacagtacct atgctgacag tttagcagca gacaaaggaa
    49561 tctttgccgt attgaatgtc atcatcggaa tcaatggttt tgtctggaac ggtacactag
    49621 caatcgccgg attgatcttt gccttttctt gggggtataa tcttgcccga gcttatggag
    49681 taaatgatct agctgggggg atcgttggtt tagctacctt gattcaaggt atttcctttg
    49741 gtccagcatt atcagcagca ttagatgtga atgttccttc aaatgtcgca gatgcaatca
    49801 atagttctga gattggtgca acgattgcag atggcacact gtcagttgga ttatggggtt
    49861 ggctaaaact agatcatttg aatggaaacg cttattttac agttatgatc atgggagcta
    49921 tttcagtcat tattttttgt aaattgatgc ttgccaacat tacgatcaaa atgcctgatt
    49981 cagtaccacc agcagtatct aaagcatttg cagccatttt accagcgacg atcgctttat
    50041 acgtcattgc tattatcaat tatatcgtag gtcgtgtagc tgatgggcaa ctgatcattg
    50101 atttggtgca aaaatatatt gcagaaccat tcctaggatt atctcaaggg ttgggagcag
    50161 tattgatcgt cacagtattt gttcaagtat tctggttctt tggtattcat ggatcaaatg
    50221 tattggcacc agtgctagag ggaatctggg gacaagcaca actaatcaat attgatattt
    50281 tccaaaaagg ttataacgga aaaactggta caccagccgt gttagatgca atcgaagatg
    50341 gaaaagctta tatgtgggtc cgcggatcgt tcgatgcttt tgcatggttt ggcggatcag
    50401 gcggaacgat cgtcttactg atagctatct tgattttctc taaacgtgca gattatctaa
    50461 cagtagctaa attatccatt gggcctggta tcttcaatat caacgaacca gtgatgtttg
    50521 gtctgccaat cgtattgaat gcaatcatgt ttatcccatt cttgattgct ccagtagtag
    50581 caacagcaat tggatggaca gctacttatc ttggcctagt cgctccggta tcgcagcaag
    50641 tcacatgggt agtaccgccg ttcttattgt cattcttagc aacaggagcg gattggcggg
    50701 caccgatcgt aacattagta tgtatggtcg tgactttctt gatttgggca ccatttgtca
    50761 tctctgcaaa caaaatggac cctgccgcag gcgaacaaca ataagatgaa cgtgaggagc
    50821 gggacgcttt aagtttcgtt cctcataatg aattttcgag gaggaactga aatgattaca
    50881 attgccagtg caatgcaaca agatgaaatc aaagaattgt tagaaggata caatgaagaa
    50941 ggaatgactt ttacatttaa agaaaaacaa ggaatcaagc tgttctttga aacaagtgca
    51001 gaagatccgg aagttgcggc taaaaaagca aaggaactaa tcaaagcaca gccttgggga
    51061 acagtccttt attttcaatc aacagctgtt tagaaaatgg tttaaaaaga taggatggtt
    51121 gagatgataa aaaacggttt atttttatgt agtattggtt ctttgatcgt gttgtatagt
    51181 ttgaatccac attcgcaaag gtatgatttg tatagtatgg tcacaggtct ttttctaaca
    51241 ggattaggaa tctatttctt catgaagggg aaaaaaagag aagaagcaaa ggagaaaaat
    51301 aactaatgga aatcacgaaa aaattaaata ttccagcatc gtttttttac gataaagtta
    51361 tggactctgt ccttttcgat gtacgtaaag cgaccggcaa atcagtaact agaaaacagc
    51421 tgaaaaattt ggagtacgtc aaacaattct cgcaaaataa ccgggctcgc ataaaaatcg
    51481 aagaagtcat tgaaaaccag tcttataagt ttcgtacatc gacaacgaag aatgaattcg
    51541 tcgttcatta tcaaatcaaa ccattggacg attcgacctg tgaggttcat tacacagaaa
    51601 aaatggagtc ttatggcatg cttcaaaagt tgaatgatat gcttttagga acaatcttga
    51661 tgtattttaa acggagacgt ttcaaaaaaa tgctagatat gatcgaagca acgtattaaa
    51721 tcaatgaaac atggtactat ttagttattg aaaaatgaag taagctagaa ggaatttttc
    51781 ataggaagat agatctttcc tgcgaatcct cactagcttt tttgtaggaa ggggcagcaa
    51841 aatgacaaac aaagtaagag agctaggtgt atcttcgatt gaggaaatgt ttgatttagc
    51901 cacttatgca tttaatgggg cagatacacc tgaaaggcga gaacgttttc gtacacttgc
    51961 ggagaattct tggaattacg gattttttga tgaggaggat cggctaacaa gtcaagtcat
    52021 ggcgacccct tttccagtga atttttacgg acaagagtac ctaatggccg gcattggcta
    52081 tgttgcttct tatccagaag caaggggaca aggcgggatc aatcagatca tggaaaagat
    52141 ccttgaagat tgccgtgatc gtaaagtaag cttatcttat ctggcgccat tctcctatcc
    52201 cttctatcgg cgctatggct atgaacaatc atttgataaa atcagttatc aactaaacag
    52261 tcgtgatgtg ccgtttatca aaaaaaaatc tggaaaaata aagcgtatgg attttgaaga
    52321 tgcaaaagct gcaatcagaa gaatttatga acagatgccg gaaaaccaac gagctggtct
    52381 gaagcgcgaa gactggtggt atacgtataa attcaagcaa aaaggcaatt accagtttgc
    52441 tttgcatttt gatgataatg aggaagcaac gggatatatc gtttatcagc ttgcaacgtc
    52501 ttcctttatt attgcggagt ggggattttt ggatcatgat gctttttgca gccttgttcg
    52561 cttcgtaagt tctcacaatg gtgcttttga aacatttgaa tattcatgcg gctacggcgg
    52621 taatgatcaa aattatctat tagaaaatcc atttgcttct gtaatgatca caccttatat
    52681 gatggcgagg atcgtagata tttctttgtt tttggaaaat tatccattta aaaagagaca
    52741 agctgcattt gccctacaaa tagaagaaga tcattatgcg aaatggaatg aaggaatcgt
    52801 ggaagtaaca atcgaaaatg gaaaaaatca tctctcaaaa gtagaacaaa caaaactccc
    52861 aatcgttcga ggaagtatcc aacatatcac gcagctatta ttagggtatc gtaaagtgga
    52921 agagttggta ttccaagaaa gaatacaggt gacaaaagaa tatgaagaaa cgttaagctc
    52981 aatcttgcca cagcaacagc caattcttaa tgactatttt tgataaaaaa cgggtgatga
    53041 caatattttt gtcaccaccc ttttgttttt catttggcat ttgaaggaaa atgttaaagt
    53101 aaatcctctt ttttcgtaaa tttgaatttt ttgttttctt ttgttttagg gttttctttt
    53161 ttgtggtctt ggattgcttc tttcgtaatc ttttcccgat tttttttaga tgaatctaag
    53221 cgttctgcgt atactttttc ttttggctta tcattcattg gaaaggacct ccctacatta
    53281 tttcattcta cctctagttt atcatctgtt aaggactagt ggaaacgttt tgcctaactt
    53341 ataagctgat ttttttagca gataagcttg caagtaaaaa acaaacaagc tacaattgat
    53401 ttattgaaat tgttcctgta gctcagtagg atagagcaat cgcctcctaa gcgataggtc
    53461 gctggttcaa ttccagtcag gaacgtataa ataacccctg tatcctttgc ggtacagggg
    53521 tttgttttgt atttgtgcca aaaatgtgcc aaactagtta tcatttttat ataaactatc
    53581 gaacacagta ttgatttttt ctttatcctg atcttcaagc tctcgaacaa tatgaagata
    53641 agtagacatt gtagtttcta aactgctatg tcctaaacgt ttcgatacgc taagtatatt
    53701 tactccttga taaagtaaaa tagatgcatg tgtatgcctt agtccatgca aagtaaattg
    53761 cttttcaatc cctaattctt ttaatttttt gcgcaaatat ttgctgacgg cgtttgatga
    53821 aactaatcca ttttttaagt tgaaaaaaac aaaattatga gggtttttga tttcaaaatt
    53881 ctcgaataat tctttttgat tgattttaaa cttttttaag agatcaatcg tatgtttatc
    53941 aatggaaatt ttcctatttg aagtttcgtt ttttgttttt ccccattcat ttaatttata
    54001 attccatgtt ttattaatag tgatgatttg atcttcgaaa tcgatatctt cccatgttaa
    54061 tcctagaagt tcagcaaatc gcattccagt ggcaccagca actaacacga gcataggaga
    54121 agagtactgc gcagaaaggt tttcttctac gagtttcatt aaagatttaa attgatcata
    54181 atctaaatat ttatcttctt ttggcttcaa tgaatctttt cctttgatta ctgcttttct
    54241 agttggatca aacggaatta atccttcttc tacggcatct ttcaacgacg ctctaatatg
    54301 gttattaaac ttaataacgg tagattttac atggtcttta gcatacttat ttaaaaagcg
    54361 ttgatatccc actctatcta aatcagaaat caataccgct ggcatatatt tctttatgtt
    54421 cattaacgta tcttcgtatt ttctataagt gataggagat actgttcctt ctttataaag
    54481 ttgcatccaa tcctcaaagt aatctgataa taatagattt ttgcgatccc ctttaaggcc
    54541 tttgttcaag ttatattcta attcgttggc ggcatctttt gcttctcctt ttgtcttaaa
    54601 tcctgatttt cttatcttcg tgtattttcc gtcatctttt ttgtatgaaa tttcgtattg
    54661 ccaactattt ccacgtttga ctaatcttgc cataattgaa tcagctctct ttctctgata
    54721 caataggaac tataaagaag cccattgttt gggttttatt attttttgca catccttttt
    54781 gcttgccggc gcaaggatgt gctatttgtc gttttaatgg tataattgga tgtgtattag
    54841 atcatccaat cagaggtgtt tattatgatt aaagtgattt ttaaaagaat aactgaactt
    54901 ccagagttta gattatttgt tgattattgg tatgtctggt tttttattgt tgcattgctg
    54961 ataggtctag atgtcatatt agaaagaaaa cttaagtaag agttgagtta ataaattgaa
    55021 ttcctaaatg agatattttg tagcccatat tttgtttgcc gacatcacct aatactatgg
    55081 agctaatcgt tttttctaac agaccaaaat cagataatct atttaagcta ccatctatta
    55141 gctcttgtga atagccagac atgctgatat ttccagtgaa attttcgttt ccacgactca
    55201 ttaagcatgc taacaattga atctcaatcg atgttaattg attcagtaca agaagataat
    55261 actcctcgtt atcccatgaa gcgttgttaa ttcgaagtaa acaattctta taaagatttt
    55321 tatacatatc tattttattt tgtgcctttg atttttctac ctcgtcattt atcccttcga
    55381 atattccaat gagttggtcc ttgttctcta agttgaaaac atcttctgga atttgatcgc
    55441 gaatgttttc taatgattcg tttaaatttt tgtagaattt ctcgatgcgt ttgaaacgct
    55501 tctcgttttt agacccaaaa taaagtgact gcacaacgcc accaatataa ggaattgctc
    55561 caataccgcc ttcaactatt aattcaagat attctttttt ggttagtttt tcattgctat
    55621 tatccatagt tacctcctat tttgtcattt cctttacaag cattgtgact cctgatggca
    55681 ctcttttgta taggttttat tattgtgcac aatctaactc ttagtggggc gtggttcatt
    55741 tattttttac ttactttact attaatcata tcccattgag cataggattt ttctatgttc
    55801 gatcctcttg aactaatttc tcctgtaaaa gttactttat cgccctttgt aaaggtatca
    55861 gcattgttta agtccttcgc aaaaattaca tatgaaactt taggtgttgc agaaatatca
    55921 ttccaacttt tatcatcgta ctctttgtct gctataatgg ctattctagt agtcattgat
    55981 tcgataacag ttccttcaaa agtatatgtt ttaccactaa tatatttagt aaaagctgta
    56041 ttttgctcag tagctggagt aatagaataa taactatcta agaaagcacc ccagtcatga
    56101 ttatttgtct ctaaaaattc ttcaaattga gttaggcttt tattgctgct gttagatgta
    56161 gtagtttgag tatcagatga tgagctttcc tgtttgttat tgtcatttgc ctcgtttgat
    56221 gaggaaagcg agaaacctac ggtagtaaaa ataatcccga taataaggag aatcataggt
    56281 gttttcttat ttgttttttt gataaatctt acaattaaca tgattaaacc tataataaat
    56341 aaaacaatac cagtaaaacc aaatataccg tccattaata gatcctcttt ctcttttgat
    56401 attgaatatt ataaaccaag caattctttt ttcttaaaat cgaattcttc ttgattaata
    56461 atcccttcat ctaacaactc tttatacttt ttaatttcat ctgcacttga aatttgtgtt
    56521 tctttggaat tattatctaa tatagattgt tgcttctcta tatatttttt taaattttcc
    56581 atttcattcc aatatttttt tgtaaacata acggtgtttt catctttcgt ggccgctaat
    56641 atacctccgc gactttcgtt tccgcctagc aaggtaaatt gtatataacc attactcata
    56701 cctggttttt ttaattgtac ggctgatata tttttaaagg ggatagtttt ttctccttta
    56761 ataccttgat taactaaatt tataaatcct tttctaataa ttgaaataga atcatcagtt
    56821 actttaatca aggtttttcc tggagatttt attaaaatct ctttttccat tttttcttcc
    56881 tcatttctgt gatatgattt tttttgtaga agctcatata tgaggaaaga gcccgtgttg
    56941 cagcacgggc ttttttaatg ttttgctgaa atcggttttt ttaataattc ttgatgtatt
    57001 catacatatt gccttgcgta agaatatttt ttcttaaaat agcattggca gacagcataa
    57061 caagtgtatc tgagcttatt ctgaatagaa taatactcca taaatttttc gagattaaac
    57121 tgagattcat cagtcagttc gttctcaata tagatattta ataaaattag aatagctatt
    57181 ttatctgctt ctgtttcaaa ttttgagtga aaagttgtag aagtatcgta caaaactgaa
    57241 aattcaaaat gagaggcgct gaaatgtgca agttcatgag ataaatgaaa ggcttctgca
    57301 gtttcaccgt atagattttc attcaaaaaa atgattctgg gttttggata gtagaaacca
    57361 ggctctttca tctccatata aactactttc aaattgtatt cgctcaacat ttctttcaat
    57421 ttcaaataca tacaaaccat cactccaact attcattttc ctctaaagct ttagcaattg
    57481 caatcgcttt acgcattgtc tccttagata tttcttttcc atcaaaagaa aaaacagtat
    57541 cgtcttctga taaatccaca tgtttagggg tttctctttc ttctctacct agaaggtagt
    57601 ctacagagac atcgaaatag tcagcaatcc gacttaattc atctgaatta ggagtattat
    57661 ttttccactt tgctagataa ccgttagaat atccaaaatt aatttctaac tgccgtatag
    57721 atatcttttt cctcttcgcc aagtctttta ttatttcata ggtattcatc gataaaacaa
    57781 cctttctaaa tgtttacaaa aaaagtttag aaaaatacgc agaaataatt tgactaattc
    57841 tgagtaatga gctatactat atcttgtaaa cagatttaac aactaaaaag acaacaaaaa
    57901 acactattga tatgtaaatg cagaccgcca agaaagcttt aaaatcaatg tttttatgtc
    57961 ttatttaatt atgctcttag tatagagtat tactcagata ctgtcaattg aatttagaaa
    58021 aaagttgtta aatttgttta cgaatataaa agaaaggaat gagaaatatg aacacaccgc
    58081 aaatttttaa tttcgaacaa aacgaagttc ggacaatttt agtaaatgat gaaccatatt
    58141 ttgtaggcaa agacgttgcg agtgttttgg gttattcaaa cactaaagat gctttgtcgc
    58201 ggcatgtaga tttggaagat aagatggggt cgcgaatcac gacctcaggt caatcaagag
    58261 agatgacaat catcaacgaa tctggtttgt acagtttaat cttaaaatca aaacttccct
    58321 ctgccaaaaa atttaaacgt tgggtaacaa gtgaagtgtt gccagcaatt agaaaacatg
    58381 gaggttatct aactccagaa aaagtagaag aagctttgct taatccagat acaatcattc
    58441 aattagcaac tcaactaaaa gaagaaagaa ctggaagatt aatcgcagaa caaaagattg
    58501 cagagtacga acctaaaatc tcctatttag atagcatatt atcttctaca gattcagtaa
    58561 caattagtca gattgcagca gattatggga tgtctccaca acagatgaat aaattacttc
    58621 ataaactagg tattcagaaa aaagtcggta accaatggtt attgtgcaaa aaacacatga
    58681 accaaggata cacaaaatct catacaactg agatcccgaa agccgatggt ggcactaaaa
    58741 ttgtaatgaa taccaaatgg acacagaaag ggcgtctatt tatctacgaa ttactaaaaa
    58801 aagaaggata ttaccctcaa atggatttag aggaaattgg ttagaaagga gttttagtat
    58861 gactgacatt gcagaaatca ctcaacgaga tagagaaaaa atcaaagaat atgtcgaaag
    58921 ttcaaagttc ttaacttaca ccatgcttgc tgaaagattt ggaattagca aaagctactt
    58981 atctttaatt ttaaacggta aaaagacttc tgcagaagca aacagaatta tagattcgat
    59041 tatcactatg tacgaattgt aaagggagga acagctaatg caatatctag aagcaaaaat
    59101 cccaattcca gaaggctatg taattatctc ccaagtggat tatgaggagt taaaaaaagc
    59161 tgatgatact ggtagatgga tgacgttgcc agaagtgcta gaacggatta acagaaaata
    59221 tgattggttt acttctagag ttttaaagaa cccaagatat agaaatatta tcgatatcga
    59281 gaaaaacaaa aatggatttg tctattatcc agttgaagga agagacacat atctattttt
    59341 aagaagtaaa acacttgaat ttttagaaac aaatttttcg gaaatcttaa ggaggcaagc
    59401 ggatgggaaa atttaataga gcgctagtgt tcagcgcacc gctaatcatc tacgctttag
    59461 gactttgggg aagcaggcaa gcgttgatag gaacgattgt ttacatggtt tggattttta
    59521 tggggcttga tgaagctgaa gctgagtaca gagcgaaaaa gccaaccgag ggggctgact
    59581 aaaaatgaat agaaaagaga aactagaatg tatattacta ttactcagtt taattctttc
    59641 actaatttct ctattgggaa gtttgtattt ttgatatcaa caattttgtg gatttgggtt
    59701 ctatttagag taaatatcat ttttgtttgg tgattaagga gtttattaaa attaattttc
    59761 cctacttcaa atgcaaggta acaagatata gcacttttag gaggaatatt tagcggtaca
    59821 gcttcagagt atattctatt atcatcgact gatcctcctt tagcaattaa tttcttaaat
    59881 ggagtagctg accatctgcg gtttaagtta gcggatgaaa gttctaaatt aactaacata
    59941 gctggttctg ttgaatagtt agaaatgatt acttttgtat aaatcatatc tgcagcgaag
    60001 taagaagcat taagttcaac ttctagttga gggcgcattc cttttatttt tatccctgtt
    60061 aaaaacgtac tcaatataaa acttattatt gacatccatt gaaaaattgt taagtgaaaa
    60121 aaattcaaaa taaacaccac cagtttttaa ctaaattata ccaaaaagga gagaagaaat
    60181 aatgcaagaa ttagtaattt tgaaaaataa agaagctgtg actacgagct tacaagtggc
    60241 agaaagcttc gagaaaaaac atcaacatgt tttaagagat attgatgcac taaaaaaaga
    60301 tgtgtccaat tttggacaga tgtttgtaga aggtaatgaa ccagattcat atggcagaaa
    60361 tcgacgagtt ttcttcatta gtagagatgg atttttcttg ctggctatgg ggtttacagg
    60421 aaagaaagct atctacttca aacaaaaata cattgaagca ttcaacgaaa tggaagatgt
    60481 tattcgcaag aatactgttc ctcaaacaat tgaagatatg atgatctatc aattagaaga
    60541 aatgaaagat gttaaaaaag atgtttccat gcttaaagat actatgcgaa ttagcggaca
    60601 acaagagttt gaaattaagc aaaaaggaaa tatgaaagtt atgggagttc tagggggaaa
    60661 agaaagccga gcttatgaag aaatcagcaa aaaagtattc tcaaaatttt ggtctgaatt
    60721 taaacgtacc ttttcaatcc caagatatgg cgagttacct cgtaagagat tcgatgatgc
    60781 tgtttcattt attgaaatgt ggttgccaga aactgcgatc cgtatggaaa ttgatcaact
    60841 gaacagacaa cagagacttt ttggtgatga caatgaatag agctgaagcg ctaagaatag
    60901 ggacggcaat tgctaattgc tggtggaaat actataaacc aatcatccta agccaacaac
    60961 atattgacaa gcaaaaagca tggcaacaaa taaaaaagtg actccgccgg caagcaaaga
    61021 gtcacaaaga aaacacatca taaggagatt ttagcatatg gaaaaagaac tttccactct
    61081 agatcaatat ttgattgatc ctgattgggg caagccgaaa attgaggaaa caagtggtcg
    61141 aaaaatcaga cgaaatcttt tgacgaatga agaactagct tgggatcaag atgatttagg
    61201 caaccatgta actatttggg atcatgttta tcttatccat ctatcgaagc attcgaataa
    61261 acctgaatat atttacgtca tcgaagatgg cttgattgat gcgctagaag agtacgacag
    61321 agataacttg attgatatct cttattacgg accaggtaag aaatacattg ctgaaatgga
    61381 ggcagaattt gatgagtgaa atcaaaggga caacgaactt tgaaaaactt tttagtcgta
    61441 agttaaataa aattctcaag aaaaaaggaa attttgatta tttatcttgg gctcacgcgt
    61501 gggagattat gaaaaagaat gatccacagg caacggtaac tattaatgag tacaaacact
    61561 acagggttgt ttctggaact catcaagact ttcttgttga ggaatataaa ccttttctta
    61621 tggatgaaac tgggacttat gtatctgtct cagtaacggt taaaggacac acggaaaccg
    61681 aattatttcc tgttttagat tatcgaaacc aaccagttgt taaaccaaat gcaatgcaaa
    61741 tcaataactc attgaagcga tgctttgtga aagcattggc tctacacgga ctgggattat
    61801 atgtatttca aggggaagat attccaacac cacctagaat cgatacaaag aaattaaaca
    61861 tgctagagac gattctagaa gctttcaatg agcagatggg taaagatatg accaaaacct
    61921 taatcgaata tgttaatgag cagacagata aattagggct cttagctgat aacgttgaaa
    61981 ctattgaaca gttaagctat gagcaatgtg ccttgatgga gcgagcaata gcagctaaga
    62041 gaaaagaatt agataagaag tgatatgagt gtttaaacca ttaatcgatt catattcagc
    62101 ggttctgaaa aagttcaaag gaaaagacat aagcgcaacc atcaatgagg aagtgaacat
    62161 tgatcgacta aagacgatgt atgacggcta cgatggtgat cgagtcattg aaattcgttt
    62221 tattgatcct agacgtttca ccgtacagca acgaaacttc atctatgcgc tgataggcga
    62281 tatttttatc gatacaggca tgccaacgga cttctggaag gaattcttct actttcgttt
    62341 tgaaggtgtc acagggcgca aaataagcct gaaagacgaa tcgaatacaa ctgtgagtga
    62401 tgccaatgtc ttagcaaata tcatcttaga tttcatcttt gaacatcata ttcctttcaa
    62461 agaaggctat gagattttac ctgcgaatca agaatattac ttctacaaat gcatcacaaa
    62521 aagagtctgc tgcatctgtg gcaaaacagg agctgacatc gatcactttg acaaagcgct
    62581 aggaagacga aagcgcaaag aagttgatca tgcagagtac acatttgcag cactctgcag
    62641 aatccatcac acagagaagc acaaaatagg tgtgattaat ttcaaaaata aatatcaaat
    62701 caaagggatc aaattaaacc agaaaacaat caaaaagtta aatattggag gggaaaaatg
    62761 acagaacatc gaagttatta tgcgattata ccagccaacg taaggtacga caaaagactt
    62821 aaaccaaata ctaagttgtt atacggagag ataacggcct tgtgtaatga aagaggcttt
    62881 tgttgggcag gcaatgagta ctttgcagat ttatatggtg tgaataaaga gaccatatcg
    62941 cgatgggtaa gtgatttgat taagtttgga tacttgaatc gggaaatcat ttacaaagag
    63001 ggtaccaatc aaataatcaa taggtaccta cgaattaatc aataccctat tgacgaaaaa
    63061 cgcaataccc ctattgacga aaaagtcaaa gataataata catctattaa taatacattt
    63121 aataatacaa aagaatatat aagagagtta ccgccttcga aaaaatcgaa ggctaagccc
    63181 gtccgtcata aatacggaga gtataaaaat gttcttttgt cagatgagca gatggagaaa
    63241 ctcaaaacag aattccctaa tgattaccaa gagcgaatcg aacgactgtc agagtattgt
    63301 gaatcatctg gtaagactta taaaaactat ttggcaacta ttcgaagttg ggcaaggaaa
    63361 gaaaaaagtg aacctaagaa cgcaagcagt ggatacaagc gcacaggaag acgagagaag
    63421 cttcctgaat gggcaatcga ccaagaagcc tatctcaaga aaaaagcgct agaacgagct
    63481 aatagacaat caaaagcacc attctaagag gtggaaaaat gaagatcgat tatctagaac
    63541 taattaatga aatagcgaat tataaaaagg gcgaggaatt agacgtcctg agagacgtat
    63601 atgatcaact cgaagaagct ggaattgaag gaattaagaa tgatcgttcg agttggagta
    63661 aactcagata ctatttcgca ctctatatcg atggaacgca attaagaaat ttagcatata
    63721 ccaaattact attcattgat tgtgttaaag gcttgcaaaa acatcttaat gaacttgagc
    63781 aggtgtaaac aagatggacc taaagacatt tacagcacag atcgaattaa tgcatcaaga
    63841 agctttaaga caaagtgtgt cgtacgaaga caagtggctc aacacatttc atggcggacg
    63901 tgagagcgca cttgatcaag tactcaaatt actgaaagga gaatgtcggg atggataaga
    63961 aagcggcaat gcagcgaatt atcgaattga cttattcaga agattggcag gaagataaaa
    64021 aaatagttgc agaagtccaa aagctcggta aatcaatgtg gactgaaaag cccaaacgga
    64081 gaacgccgag aaagattgca atctggcatg gtgatcgaat tctagtaacg ggtaccgcta
    64141 aacagttatc tgaaattact ggtctgagca aaaatattat ttgggataga gctaggagct
    64201 tatggattga ttcaaaagga agacagttta ggtatgtgga ggagaaataa tggacgaact
    64261 aatcgcgaaa gtagagcagt gggcaaaaga taagggattg gatcaagcgg atttcagcaa
    64321 gcaaatgtta aaaacggtcg aagaaatcgg ggaagttgcc gcttctctag ctagaaaaga
    64381 tgaacatggt ttaagagacg gaattggcga tgtagtagta accttgatca tcttggcaat
    64441 gcaaaatgat atggatttat acgagtgctt ggattttgct tatgacgaaa tcaaaggtcg
    64501 gactggaaag atggtcaatg gtgttttcgt taagtccagt gacctgaaat aattccatta
    64561 atggaagaaa taactgaata ggaggataga catgattgat gcaaaacaag tgcaaaaaca
    64621 gaaagatgga atgttgatgt ttgaagcata tgttctacca tttcttaatc aatttgaagt
    64681 tttggaatgc tctgccagcg gagaagaatt ggagtatgtt gtaattcgtg aaaccaaaga
    64741 aaacgttcag aagctaaacg aatttctttg cactattaac tgttgggata tgatagctcc
    64801 aggattttta tgtccagcta tgggagaatt tttggaatat tgtcgtcttg aagatgcagg
    64861 cactttggat ttagcttatc tggtatacaa ctacctaaac atcaacacag atcatttgtg
    64921 gtttggcact gccgaaagaa aatgggtagt ccgctaacca ccaatatcaa tgaaaaaagg
    64981 cggtttcctg aaagtggaat tgccgccatt gctgtaaggt tctttacgcg actcaaggtc
    65041 acagaaatat aaatgcaaat ctcttttgaa gtgatccaaa gctctcggaa aatggaagtt
    65101 ttttgtttca aagaataaat gagatttgcg tcaagaacct gagagttatt tccaaaaaag
    65161 cttccaaaga accgaatgag ctaaggacat catgtgtaaa cacataatat agctctcctt
    65221 tcacggctaa tcataacatg aaaaatattc gatgtcagta ggaaaaaagg tgaattatga
    65281 aaagaatatt aaattatccc ggcagtaaca gattctgcaa ttaaactccg aagctgatgt
    65341 atcagtatca actgtagaat attatgagcg tggagaaagt caagcagtca caaatgtaaa
    65401 aatcgataac gtcaacggtc ttatctgttt agatgaaggc gatagtatga atgaaattgc
    65461 tgcagaccat gaattatcag aaactgcttt aattgatcaa atcgaattag ctagacaata
    65521 ctttgttcca tatgcagata cctggtccaa gcataagaat gacatcattt ttccagagga
    65581 acaatgagag caactgatcc agtaattatc cttgaggaag ccaaatttat ttggactcac
    65641 gaagagatag agcaagcacg cttgctcttt tctcaaggag ttaagccgag caaagtagct
    65701 gaaataatgg gtcaaaagat tcttgatgtc ggattgcttt tgctccatct agcagaaaaa
    65761 atttgatttg aggtgaaaat gatgattcaa cttgcaggca tccaaacagg gaaaatttat
    65821 ttttctggag aaagcaaaag cgaagccaac caatggctat tgaaaactta cacgaacaat
    65881 aagaagctaa ggaaaaaata tcctgatttg ttgctaaagg atgatcagat tatgccggaa
    65941 ccgatgattt tgacccgtaa ggagggaagt tgaaactaaa aaaccagccg tgtgggctgg
    66001 agttgctatt tctttttaat aatgagtttt tctaaattta attcattctc acgagtttgc
    66061 gtccaataat cagaataata ttttaattgt ttaagagtag gaatgtcgtc ttcggtaaaa
    66121 ttagaaaata attctggaga attatctttt tttaattgtt ctaatcctga ttctttaaaa
    66181 cgttgttcaa cgagttttac taaattgttg atattcatga taaatcacct ttttaaattt
    66241 aatttcgatt tgattaatcg atacaagtat tatatcaaat aaaaaagctg atttaggggg
    66301 tcttacaaaa acactaaaat tttttcaaaa agaggaggaa cggtggtgaa agtcagagaa
    66361 caattcaaga tagtgagcga cgaaggtaat gtttacaaaa taaagatcgt taatattaat
    66421 gaatatcgag aagcagatca caaatatttg gttgacttat acatgaacga taaatatttg
    66481 ggagaaggat tttgtggaga ttcacttttt gatgatgagc gaattttgaa ggaggaaaca
    66541 gaatgatcca cgaactaaaa atactaccag aatattttga agcagtgacg agcggacgca
    66601 aacaattcga gatccgcaag aatgatcgtg acttcaaagt tggtgatcag ttaatactac
    66661 gtgaatataa aaaatacatt aaacatgaat tacctggact aacgagacca acatttagtt
    66721 acactggtga ctcatacaaa gcagagatca cttatattac tgattacatg cagaagtccg
    66781 gatatgtagt gttggggatt aaaggggtga attaaatgaa agtatacatc ttagctatca
    66841 cagagggcac atggatgttc ccagtcggtt ccggaaaaat ctataaatca aaaacagctg
    66901 cttataaagc atttgaaaaa tacaaaaaag aaaacggtgg cggcactaac gcaaagattc
    66961 tagtggctga taactggcat gaagaaggtg aacgtaattg atttacctgt tcattttcgt
    67021 ggtactaact atttttatgc tagtaatctt attcaaaaaa agatgagtaa agacgaacga
    67081 aaaattctgg ccaactttta tttagtatta aaaatcgaac aaaatgtgtt ttcggaaagg
    67141 agaattgtat gggaaaaaca aaatcaaaga ttaagaagaa aaaacgacgt ttggaacaaa
    67201 aggcaatcca gaatggaacg gctaagaaaa aataaaaaag ctaccccttt cgagatagca
    67261 gcgcaatact attctaccat aaggggtggc gtttgtgaga tttcattggt taaaagatta
    67321 ccaagaacta gatgagcaga ttctttactt aaagtggaat cttaataaaa gtaagcttga
    67381 attgaatcga tgggtctgtg gtgatttagc aaacgtccgc atcgaaaaga attcgagaac
    67441 ttcttcttta gaagagaata tccaaaagat agaaaatgaa ttggaattgt tgatcgagca
    67501 aaaagaagaa atgttattgc tgatagatag cttttctggt atcgataatc aaattgttaa
    67561 gatgaaatat gttgatcaaa tgagcttaga agatattgct gaatctgttg ggtatagctc
    67621 atcgtatgtc agacagcgac atgcagaaat tagaaagaca ttgaactttt tagatgagta
    67681 tgaacacaga caagctgacc gattgaaaaa agaaaacgaa attgattttt acaatagcga
    67741 gaagtacaaa gaacaactct ctttattcta aaattacact gttcactaaa tgttcgtaaa
    67801 cattgttagc agcatgatat tctattagtg tcaaaaaaat atgaaagagc caagatatcc
    67861 caaccgtttt attaattggt atctgtggct cttttattct tttaattagt agttggcata
    67921 aagttatttc catttataaa ttgatcagct aaatcagcat cataatcagc cgcgataaat
    67981 tgcgctgctg atttaataaa tgcatccata tcatgaacat ctttattagt atgtctacga
    68041 acatagtgcg tttcatcatt accaatccaa gtagcagctt tggctaatct ttggagttta
    68101 ggaaaatcat tcaaataatt ttcaattgtt ttacctaata acattttttt tattttatct
    68161 tcatcctctg aatttttaga tattgcataa tctttaatta gaaattctag agcttttcta
    68221 taaccaactc cagcaatttg ttccaattgc tcagatttag cttgtgtggc ttgagtataa
    68281 atatcaacaa atgtaggaga aactttttca atattttctg gtaaatctat tttaatcggc
    68341 ggacggtaat aatctttaat taaaatattt tcagaatatc cttcatcttc attaaacgta
    68401 tttataaatt gtaaactata aaatttgttg cactcatcat ttatacactg tactaatacg
    68461 ccaaagattc tatcattatc gaacgcacta tatgatgaaa ccccaaaata cacatacgga
    68521 gtcattatat ttccgcaatg cggacaacta tttggcaaat aaattgtctc tgtattttga
    68581 cgatcacgat acttaatatt aacttcttga agcattaaaa cacctcgcat cttttttata
    68641 aatcatacca caaaatatct gataggagag taaacaaatg aatgattttc atgaagcggt
    68701 acttagtatt gaagtagaat caagtttggc taaagtttat aagaaagcaa ttgaagcaga
    68761 gaatagtccg tacagagaaa attggaatgg taatcatgca catgtgcaag tggagaatga
    68821 tgattacaga actggaatga atacgttagt tatttcttta ttgtcacaca ctctacccaa
    68881 tctgcaggaa acgattgaat ggtatgagcg aatgggcgca aaagtaatcc gtacaaatta
    68941 caaaggagag aattaaaatg gcaatgatca aaattagaac atccattagt ggaacagagt
    69001 attgggattc agaaaagaaa aggacagtag ttgttccgaa agatcaagaa ccaaattttg
    69061 aagtaaaaga agaaaaagga attttgagtg atggcaaatc atttgttgct gtcaatggcg
    69121 aactcatagc tcatagcagt gaaattcttg atagcgatgg aaacactgct gctaattttg
    69181 atggagacga agctactaat gatcagtcca ctgaagatac ggatgaactg gacaatatga
    69241 ctgcaaaaga attgcgtgca tatgctaaga aacatggtat tgatattcct ggtgctatcc
    69301 gtgcaaaagg cgatatcata aatcttattc gtgaagtaga atgaaatact gtcagtttga
    69361 cggatgcacg aacaaaatag caaagggtat ctactgtact gaacacaaga gatcaagcag
    69421 atcacgcaag aagaagcagc aagcaaagtc tgtttatcat catgagaaca aaccattcta
    69481 tcgaacgcaa gcatggaaag atatgcgtca atttatttat gaaagagaag gtggtcattg
    69541 tcagcggtgt ggtcagttca tatttggaaa gagagcacac gtccatcaca ttgtaccaat
    69601 caaagacaac gaactgctta agcttgatcc aaacaatctc atgctattat gttcaaaatg
    69661 tcatccaatt gttgaaaacg aaacggaaga caaaaaagtt tttccttcgt atttcaattg
    69721 aagcccccct attcattttc aaaatttttt cgcgtgggga gatagggtag cggggagtca
    69781 cgcgcatcgt taggtcaaat ttttcaaaaa acaaaggggg gtgtatacaa aaatgacgac
    69841 taaagcgcaa cgtaaagcga ttattgatga aaaagtaagt gctgaaaaag ctcgtatctt
    69901 agaaataatg aatttgtctg atttgtacac catcactctt gatccattaa tcgaatcata
    69961 cttggatatt tttgaaattt accaacacaa atatttattg tggaaggaaa aaggatttcc
    70021 ggagacgcaa aaattcacga ataaatcagg agctactaat caatcaaaac atccattggc
    70081 acaacaagta gaaacttggg cagataagaa gatgaaagct ctagatttat taggattaac
    70141 aaacaaagca aaaactggta gactaattgc tggaggatcg accgcaagaa aagatgaaga
    70201 aattacacgc ccagaagtaa agccagtaga tgaactagca gcgcacagaa ataaatggcg
    70261 taagaaggca ggtgctgaaa aatgattgaa cctggtgtaa attatgctga tttatttgca
    70321 aaagaagtaa gaaagaaacc taagaagtat cctaagaccg ttcgtttagc aatagatcgc
    70381 tggtatcagt ggaaaaaaag aaaagatatt tggtttgatg tagatcgcgc gaatgaaatg
    70441 atggattggg tagaatcatt tattgttcac acaaaaggag aaatggtggg aaaaccgttt
    70501 cttttagaac cctgggaaaa atttatttat tcttggattt atggttgggt taaagaaaat
    70561 gaaaaaggcc aaattgtacg cgttactcgt gaggcttatg tccagattcc aaaaaagaat
    70621 ggtaaaacat tgattgctgt cggttcatta ggatatgcaa tgtacggaga aggggcgtta
    70681 tcagttgatt gctatgcttg cgcatctgat tttgctcaag cgcaatatgc tgccaaacct
    70741 tttgcagtta caatcttaaa caatccaatc ctacttgaag gaactaaaat atttaggggg
    70801 ccaaagggaa ctgtttctag tattacttat gactatattc atgaagatat ggcttactca
    70861 aataaattta ttgttcaaac caagaatatt gataatatcg agggatccaa tccatatttt
    70921 gtattgaacg atgaattgca taaacaggag aaaatggaac agtatgacaa ttttaagtct
    70981 gctcagatat ctttaccaca gccattgatg tttaatatct caactgctgg gaaaggttcg
    71041 tcgtctgttg gaatgcgtgt atatcgcgaa gcaaaagaag tgttgaaacg tgatgataat
    71101 gattcaaact ttgttctaat ctatgagcca aataaaaatt atgattggac ggatagaaaa
    71161 gtctgggaaa tgtgcaatcc taactgggga atatcagtcg atttatctgc tttagaatcg
    71221 gcatttaaaa cagcgcaacg gtcagctcat tccaaagctg aatttctaac gaaacacttg
    71281 gatgtatttg tgaacggcgc ggataatttc tttgaacagg atcaagtaga gccatgttta
    71341 gttaccacac aagaacttgg tgatttaagt ggcgaaccat gttatatcgg tttagattta
    71401 tcacgtacac gagatttgac ctgtgtatct ttaaacttcc caacatggga tgaagatggt
    71461 aaagcggttc ttaaagtaaa gcaactttat tttattccga atgaagattt agagtttcga
    71521 gaaaaagaag ataatgttcc ttacagtgat ttggctgaac aaggtttcgt tgaattttgc
    71581 gacggaaaaa tgattgatca agatcagatt ttgcagtaca tagaggactg catgaattta
    71641 tatgatattc agcaagtgaa ttatgatcca gcgatgagtg acaaacttgt tgagaaatta
    71701 gaaaacttag gattggaatg cgttgaagtt gctcaatatc ctaaagtatt gaatgctcct
    71761 tttgacgatg tcgaacggtt gttttatgag aaacgaattc aatttgataa tccattattc
    71821 ctttattgca ctttgaacgt tgtagcaatt actaacatca atggacaaaa agcgccaagt
    71881 aaacgtcaat caaagaaaaa gattgatggg ttcgtggcgt ttttgtgtgg tcataaggaa
    71941 acgatgaatc aaatgacaga tattgattca gatgagttag atgattacct aagttccatc
    72001 tatagataaa tagaaaggcg gtgaaaaaaa ttgaaattac gtgatcggtt atcgaatgca
    72061 gtctattctt ttatggaaaa acgtggatat atcgaggata tttttggaca ctacacacgt
    72121 tatggtcaaa gatatgtgac ggattcatct atcatggaat cttctgatgt ttatgaatta
    72181 gttcaagaca tatctaatca ggtggcattg gccacaccaa ttgttattgg tcccgacggc
    72241 aacgaagtca aagatcatca cttactaaat attttgaaga gtcccaatga ttatttgaca
    72301 ggattcgaat ttaccaaatt ggaaacaaat actttattga tcaatggtga gacattccca
    72361 ttaacggata gggatcagct tcatttggcg tacggtgtaa caactaaaat caatgaacga
    72421 cttcaagaag aatttgaaat gaatggtcaa aaaatacctg gtcaaatgat tcgacacatt
    72481 aagaacatcg gaactgattc attaaaaggt gctggaataa ttgatcttgc aagaaacact
    72541 ctagaaggcg ttctgagcgc tgaaaaagtt ttgacggaca aatatactaa aggcggttta
    72601 cttgcgttca tgcttaaact agacgcccac atcaatccaa ataatagcgc ccaaacaaaa
    72661 attgtcaaag ctatattgga tcaactggaa ggaacgcaaa atgagagtga tcattctgtt
    72721 aagatgattc ctttgggaaa aggatattcc atcgagacat taaaaagtcc tgttgatgac
    72781 gcggcaattt tgaattattt aggtgtttac aaaaaagact taggaaaatt tctaggaatc
    72841 aatgttgata cgtatcaatc gctgatgaag acagatattg aaaaagcgat gatgtatctg
    72901 cacaacaaag caatcaaacc aatattgaaa aacaagagcg aacattacac cgctcttttt
    72961 tttatgccta attctggcta tagagtggaa tggaaaatta atattttgga ttttgttcct
    73021 tactcaacaa aaacaaatat tggctacaac atcgttcgta ccgggattac aagtccagat
    73081 aacgtggcag aaatgcttgg ttttcctaaa cagaatactc cagaaacaca agctatctat
    73141 atttcaaatg acttatctag gattggccag aaaaatgcaa cagatgattc cttaccaacg
    73201 aatgatcaag acttgaaagg aggtgatgga aatgaagaag aaggaaattc gcacgattga
    73261 catcaccaat ctttcaacac gttccgatga agaaactcat acgaggacca ttagcggcta
    73321 cgctgctgta ttcaacagtc aaacactttt atgggatgac ttaagcgaag tgattgttcc
    73381 tggtgcattc tcaaaggcaa ttagtaattc ggatgttcgt tgtttgttca atcacgattg
    73441 gtccaatgtg ctaggacgta ctaaaagcgg aacccttcgc cttgaagaag atgaacgtgg
    73501 tttgaaattc gaagttgatt taccggacac aacggtagca agggacttag ttaaatctat
    73561 ggaacgagga gacatcaacc aatgtagttt tggttttgtg ccgactgaag aaacgtggga
    73621 ctacaattct gaaccaatgc ttcgaacaat ccatgaagtg gaattatacg aggtttctat
    73681 tgtgcctttg ccagcatacg aagatacaga agctgcatta agaagtcgtg atgaattaga
    73741 aaaaaacgtc gaagaaagaa aaaaattaat caaaaaaatt aatcaagcgc tagaagcgta
    73801 ggaggaaaaa tacatggata aagaattatt gaaaaaaatg aaggcacgtc gtgagcaacg
    73861 attgactgaa ttacgtgaaa aagttgaatc aggagaatta cgcgaagcag atttagaagc
    73921 cgtgaaagaa gaaattgaca gtgttattga tgaattgaac ggaattaaag acgaattagg
    73981 cgcagattct ggaactgatg aaacagacga caatacagat gatcaatcga atagtacgga
    74041 ttcagacgaa agccgttctg gtgaagacaa cgatcaagaa gaagattcag acagtgaaga
    74101 tagttcagaa aatcgttctg gaatgattac tcaacagcaa cgagatggat tacttggatc
    74161 aattaagaac ggattggagg cacgtgcaaa aatgaccaag aaacaaaaag atcaacaact
    74221 acgaaaagca tttgctaatt ttgtagctgg aaatatttct gaagcagaag ctcgagcttt
    74281 agggattgaa gctggcaacg gttcagttac tgtcccagaa gtaattgcat ctgaagttat
    74341 tacttatgct caagaagaaa atttacttcg taaatacgga acagtggtgc gaacatcagg
    74401 agatgtcaaa tatccaattc ttgtgaagaa agcagatgcg aatgtaaaca agaaagagcg
    74461 ttcaactgat attgctgaaa cagctattca gtttgatgaa attttgctta atcctgccga
    74521 attcgatgct ttggcaacag taactaaaaa attattaaaa atgtctggtg ttccagttga
    74581 agatattgtt gtggaagaat tgaaaaaagc ttatgtgcgt aaagaaatca attatatgtt
    74641 caatggtgat gacgctggaa atgaaaatcc tggtgcatta gccaaaaagg ctgtagcatt
    74701 taaaaaacct ttagatctaa ctgcttcagg tgctgggcaa aaattatatg atgcattaat
    74761 cgaatttaaa aatacaccag tgacagaagt gatgaaaaag ggacgcttta ttattaatcg
    74821 agctgctttg actgccattg aaaaaatgaa aacagatgat ggatttcctt tgttgcggcc
    74881 attcacacaa gcagaaggtg gaattggtta ccaattagtt ggctatcctg tggattggac
    74941 agatgcagca gataaaaagg gtgaaccaga cacgccagtt ttatattttg gcgatttttc
    75001 tgcatttaaa attcaagaag ttattggtgc cttggaaatt caaaaacttg ttgaaaaatt
    75061 ctctggtaaa aatcaaattg gattccaaat ttacaacttg ctagatggtc aattggttta
    75121 ttctccattt gaaccggcag tatatcgcta cgaaattaca aaaccagttg gtggttaaga
    75181 tggaagagca aactaaagaa ttgtctttag aggaaaaatt caaatcacat attcattttg
    75241 aagagggcat ggatgattct ttgctctctt tttatttaaa tatggcaaaa gattatgtca
    75301 aaacagcaac tggtggccaa caagaatatc ttattttgat ggttgccggc attgcctatg
    75361 aatatagagt ttcagaggat gaactcgaca aagctatgaa tgccatgacg ccatttatcg
    75421 tgcaaggagc gattcaaaat gccgaagaga cagactaata atctcagatg gaaagccgaa
    75481 ttgctagaca tcaaaacagg aacagacgga aacgatcgtc caactacaat ttacgaattt
    75541 aagcgtctaa tattctatga agaactcggt gtgacttctc aagaaaaata tttatcacag
    75601 caagccaaga cagacgttgt cagacgaatt aaagtcagat gggataaatc catcacagag
    75661 aaattaagtg cgctcaaaat tgattctgta acgtataaca ttactcgcat ttatacgaat
    75721 cccgatgcaa gagaaatgga gttgagttta gcttatgtcg attagctttg atgaattgaa
    75781 aacagcgctg aaatcaacaa agttagcagt gttcagagac aaagccagat tagggacgat
    75841 gtatccatac attgtgtact caaatgtgag taacagcaaa aaaatggcat ccggtaaagt
    75901 ctataaaaaa ttaccttatt accaagtctc tttttttaca cttggaacag aacaggattt
    75961 agttgttatt gaacaagcgc tgcaaaatgc tggcattcca tattcagatt ttacaggtat
    76021 acaaggtgat gagaacgacg ataccgtaac caactattac acatatgtga ggtgtgtgga
    76081 aaatgccaag taataagaat ggtttttctg aaatatcgga ttatttagga aacctttcaa
    76141 aagttgatcc gaaaaaatta tcgttggaat ctttagaaga agcagctaac ttttatctaa
    76201 agcagttgct tcctaatatt cctaagtcgc tcttaaaaaa gaaacatatg cgcgatcaaa
    76261 taaaagtagt agttgaaaac gatcaagtga aagttcaatt tgaagagacg gccttttact
    76321 ggcgctttgc cgaaaatggc acaacaaatc aacgtgccca acattttgca agtggtacgt
    76381 atgaacaaaa caaagaaaaa attgaagaaa ttatgactag aaaaatactt gatttatggg
    76441 aagggtgatt ttaattggga aaacaagata ctttttattt tgaaggattg gacgacattt
    76501 taattgcgat gatggcaacg ccagattctg ttggaactgc accgacttat agtgaagttt
    76561 tacgattgcc aattgccaca aaaatcggtg tcaaagggaa tggaacagca ttagaaaaat
    76621 gggcatccag caaaatgttt cgtcgtgtgt cgcgagaaac aaaacatgaa cttgcgttgg
    76681 atcacgtggg tattccgata gaagtgatgg atgaaatcaa aggattagtt gctaaaagcg
    76741 gagtaacgtt tagcaaaaat accgcacgag aatttccgta cttcgccttt ggatttattg
    76801 gaaatattga aaatggcggt aaaaaagcag tttggtatcc taatacacaa ctatccaatg
    76861 tgattgacga agagtatgcc actgcagagg aagaaacaaa aattgacgat gtaactgcaa
    76921 atctggtttc catcggactg aaatacaata atgtgatgta tgcaagtttt gattcaaata
    76981 gagacggagc ttctctagaa ttatttaata aattcattgc tcaacctgta tacgatgaag
    77041 aacagtggaa aacattggct aaagttggag gtgcgggtta atggctcggt tatctgatta
    77101 tggaattcac gttgaagact taaaaaattc tgctgttgta attattcaag gcgcagaatt
    77161 ccctatttca tttactatgc aaacgatgga atttatagca gatgtgtatg gtggagatta
    77221 ttcgcaattt gaatctgata tgaacgccat gctatctaaa aaagaaggac aaatttcttc
    77281 tgctaactta tcgcctagtg atctaaaaat catgcgtgcc ttgatttatg ccatgctgcg
    77341 tactggtggt ttagaggaag atccagaaac tattttcaaa tttttgggaa tgagtggaga
    77401 ggtgttgtct gcttatagta cctgtatgga aatttttgct agccagacat ttcaggtgga
    77461 agacctaaaa aaatccaaga agccacaaga ctttcaaaaa gcgcaagcaa aaagaaagaa
    77521 aaacaaaaag aatcggaaga gataggaact ccttggagtt tttatattta cgttgctctc
    77581 actctattga attggagtga gagtttcttt ttaaagtcta cacctaactt gtggctcaaa
    77641 tcttatttac agtggttaca acaaaacacc gattttgaac cacctcaatc tgtaactatg
    77701 gataaatcgc cttggtggta gaaaggagcg ctaagataaa tggctggtaa agaatctgat
    77761 gtcgttctta attttaaaac gaatggcgaa gtcagttatt cgaaaacaat caaagaaatc
    77821 aacaaagaaa tgaacttagc cgctgccgag tacaaaaacc aagtgtctgc gatggacaag
    77881 gatgcaactc aaacagaaaa attgcgagcg gctaaacaaa aattagaaaa acaattagga
    77941 ttggctgaac aacgatctca aatgctgaga gaggaatatg aaaaatctgt caaagaaacc
    78001 ggtgaatatt ctgctgaatc agaaaaactt tataaacaat tactcaattc tgaaaccgga
    78061 gaaaataaac ttcgtacagc attagaacag acgaacgatg cacttaaaga acaaggtgac
    78121 gtttctgttg atacagcaaa aaaactccag aaaatcgaag aaacaggtga gaaagtaaaa
    78181 ggcgttggtg aaaaaatgtc tgttggagta accgcgccta ttgtagcggc aggagcagca
    78241 ggacttgcag catttggtga agttgacgag gcacttgata ccatcattac aaaaaccgga
    78301 gcaacaggtg atcaagctga tagactttca cagtctttca aaaacgttgg ttcaaatact
    78361 catttacctt tacaaacggt tggggaagct attggtgagg taaatacaca atttggattc
    78421 atggataaaa aactggaaga ttcaaccaat tatctcctac agtacgctga aatcaatgat
    78481 acagatgttt cgcaatcagc aatatctgct cgacaagcta ttgatgctta tggactagaa
    78541 tatgatgatt tgaattctgt ccttgatgta acaacgaaaa catcgcagaa tactggtcaa
    78601 tctgtagacg acttgatgca aaaagcaatt gatggcgcac cacaaattaa acaattaggg
    78661 ttgagctttg gtgaaggggt cactttactt ggacaatttg agcaatctgg tgttgattca
    78721 agcgcagctt taagtagttt atctaaagca acagtggctt atgcgaaaga cggaaaatct
    78781 ttaagtcaag gactagaaga actacaagac aaggtaaaaa atgcaggttc tgaaacagaa
    78841 gccatcaatg cagcagcaga agtattcggg actaaaggcg gtcctagaat ggccgatgca
    78901 attcgtagag gtactttgaa cctggaagat ttagcaaaaa ctgctggaga aagtggggga
    78961 gctgtaggag acacattcga tgctactctc gacccaattg atcaagccga tcaagctatg
    79021 aacaatgcaa aattagcaat ggctgacgta ggtgaagcag tccaagtaag ccttttgcct
    79081 ttttttgaaa aagcaacttc cttattacag gaattctcta aatggtgggg gtctctagat
    79141 caagatacaa agaattggat cataacaatt gctggtatag cggcagcagt tggaccagta
    79201 ctaatcgttc ttggttcact tatgggatct gttacaaaaa tcgttgggga agttaaaagt
    79261 tttataggag tttggcaagg acttgctggt ttatttggaa tgtcgggagg ctggtttgca
    79321 ttagcagtta tagctattgg cgcattagtt actggactaa tttgggcata taataacgtt
    79381 aaatggtttc atgatggagt gaattctttc ttcaaaggtg tttcagatgt agctgttgaa
    79441 atatttaatt ttttaagtgg ttattttggt ggatttttcg atggtgttat agcaaatttc
    79501 aataattttt ataatgctgg aaaacgaatt ttcagtggtt ttctagattt tatcactgga
    79561 gtatttacag ggaattggtc aaaagcatgg caaggtctag ttgatatttt tggaggtatt
    79621 ttcgatggta ttgttgctgt agggaaagct cctattaatg ccatgattgg attgatcaat
    79681 ggatttattg gtggattgaa taatataaag ataccaaaat gggttcctgg tgtaggtgga
    79741 aaatcatttt ctatttcaaa actgccttat ttagcacaag gcggtcatct aatcaatgga
    79801 caagcgattg ttggtgaagc tggacctgag ttactgactg ccaagaatgg taaaaccaca
    79861 gttactccat tatcagacga agaaaaacgc aaagggatca gtggaagagt ttctggaggt
    79921 agcattgaac agcatataca cattggcaaa gtcgatgcaa acaatccatc tgagttagat
    79981 cgtatgaatc gtaaatttgc taaagcaaac aaacaggcta ttcgtgattt gggaggtgtt
    80041 cctatttgag tcgacaattt atgaatccag atgaaccaaa ttttatttgg aaaaatcgga
    80101 atgcagtaat tgatatgaat tgcatcattg aggcagagct tccagatatt atgccgaaca
    80161 agcgatacga aacttacacg attcagggcc gaagcggaga attgacggag acgtttgatg
    80221 actatgaacc ttttgatttg gaaatagaag ggatcactat tccacattcg aaactgagag
    80281 aagtcaaacg atggctcact ggtaaaagcc aattaatcac acataatgat ccagacaagt
    80341 atctagaggc tatctgcagc atggataaag aagtcccttt cgaaaacgag tggggcttct
    80401 tttatacatt cgatgttact tttcgttgtc agccactcaa aagaaaaatc ggtgaagcac
    80461 ctaaaatttt tcattctagt gttatggata tttttgatca tggtgacgaa attgcacatc
    80521 cctatctgga aatagaatcg aacggaggag atataacgat cgctgtcggt gataaaagcc
    80581 taacaatact taatacgtta gctgcaacaa tcgtggttga tactcagctt ggaaaagcaa
    80641 tacaagaagg tttgaattta tttacgcgtg gtgattggcc agtattgcag cctgaatgga
    80701 atcaggtaaa aatatccgga aaatttaaag aagtgcggtt ttggaatagg agtgtgtatc
    80761 tgtgacgcaa gaatttattt atgcttataa aaaaatgcca gatgatttga gcgtgaacgg
    80821 agcgtcgtta gttgattggg aagatttgcc agaaatcaat cgtgtgctga atggccaata
    80881 tcgtttttat ggtaactatt caagaagcgg acagtatcgc tcttatttaa aaaaaggaaa
    80941 ttttataaaa gcgaaggtac cagatggatc atggcaatat tttgaaattt ataatgtcaa
    81001 aaagaatttg acctccgttt ctgtaacagc tcggcatatt ggttttatgg ccaataagaa
    81061 ctttattgtc aagtcgttta cggataacgg caatgggtct cagatcatga ccaatcttaa
    81121 aaacagtttg gcatttgatc aaaaatttaa ctatctttcg aatgtaggga caacgcacca
    81181 atttacagca agacaagtcg cgccagttga agcaatcatt ggttcaaata acggtaatca
    81241 aaatttgact ggcgtgacta gcgcggaact tgatatggat aactatgatt tgaaactggt
    81301 aaaacagatt ggatcagata atggttttcg gattgatttt ggcatcaatt tagaagcaat
    81361 cgaagaagaa attgatgaag aatcaattgt caatagtttg tatttggttg gcggtgttcc
    81421 tgataacgat tatgatgaag acaaagaacc tatcgaatat ggttatttag aaattgatgg
    81481 agtaaccaac gagaatcgac gtattgccaa acgtgaaaac ggagattgta aaacagttga
    81541 tgaattgatc aaatggggca aaaccttatt tgacaatgat cgtatccatg agccaaaagc
    81601 tactcataca gtcagtatgg tggcgttgga acacacactc gaatacggtg acatgtatca
    81661 agagctagcg tctttacact ttggtgatgt cgctcatgtt agggcgaaag agctagatat
    81721 cgagataaaa gagcgtatgg tcgaatacac ttatttccca acgcttggga aatataagga
    81781 tattgtttta ggtaatgatt tatcactgta cacttcggca gtaaatactc aagcacaaga
    81841 attgaaaaag aaaatcgaca atcgaacaga aacgttagtt caaaatgtgt tgaatgcgac
    81901 ggcatggatc actggtaatt ctggtgggca tgtcgttttt cgtccagaaa aagctccatc
    81961 agagattctt atcatggata ctccaaatgt ggcgaatgca aagcgagtgt ggcgttggaa
    82021 tttaaatggc ttaggttatt cagacaacgg agtaaatggc ccgttcggta ttgctatcac
    82081 atcaaaagga gaaattgttg ctgacttcat caaagtagga acaataaatg cagaagtatt
    82141 cgaaacttcc tttaatgctt atggtgatgt gttaaaactt gtaaaaggca cgcttcaaat
    82201 ttggaatgaa aacaaaaaaa tcatggagct aaccaaaaaa ggtatggaat tctggaatag
    82261 aaaagaatcc attggaacga tcggaacaac agattcagca ggaaatccat ttccaaatgc
    82321 tgtaacacct acacctcttg aggaaaattc tttggtaata cgtacaaatg gcgatggaaa
    82381 atacatttta atttctccaa ctgcagaaaa aggatttgtg ttattaggaa acggaaaagc
    82441 atattatttc ggtgatttag atattcaggg aaaacttact gttagaggta aagaagtgat
    82501 accaggacaa aatggcggtc catctggcgg aggagaaaca cctggtgggt atcctgatga
    82561 attaaaaaca gatgcagaaa agagagcttg gagaat
//
LOCUS       DAZAOD010000003        79460 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000003 DAZAOD010000000
VERSION     DAZAOD010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 79460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.003"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(12..617)
                     /gene="dhaL"
                     /locus_tag="ACHDPO_000201"
     CDS             complement(12..617)
                     /gene="dhaL"
                     /locus_tag="ACHDPO_000201"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFN3367869.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="ACHDPO_000202"
     CDS             complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="ACHDPO_000202"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFN3367870.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(1630..2025)
                     /gene="dhaM"
                     /locus_tag="ACHDPO_000203"
     CDS             complement(1630..2025)
                     /gene="dhaM"
                     /locus_tag="ACHDPO_000203"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFN3367871.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            2179..2499
                     /locus_tag="ACHDPO_000204"
     CDS             2179..2499
                     /locus_tag="ACHDPO_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFN3367872.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(2611..3468)
                     /locus_tag="ACHDPO_000205"
     CDS             complement(2611..3468)
                     /locus_tag="ACHDPO_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFN3367873.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(3576..4880)
                     /locus_tag="ACHDPO_000206"
     CDS             complement(3576..4880)
                     /locus_tag="ACHDPO_000206"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFN3367874.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(4877..5386)
                     /locus_tag="ACHDPO_000207"
     CDS             complement(4877..5386)
                     /locus_tag="ACHDPO_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367875.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(5561..7696)
                     /locus_tag="ACHDPO_000208"
     CDS             complement(5561..7696)
                     /locus_tag="ACHDPO_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFN3367876.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(7779..9434)
                     /locus_tag="ACHDPO_000209"
     CDS             complement(7779..9434)
                     /locus_tag="ACHDPO_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFN3367877.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(9436..9750)
                     /locus_tag="ACHDPO_000210"
     CDS             complement(9436..9750)
                     /locus_tag="ACHDPO_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFN3367878.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            9920..10180
                     /locus_tag="ACHDPO_000211"
     CDS             9920..10180
                     /locus_tag="ACHDPO_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFN3367879.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            10194..10508
                     /locus_tag="ACHDPO_000212"
     CDS             10194..10508
                     /locus_tag="ACHDPO_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFN3367880.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(11238..11792)
                     /locus_tag="ACHDPO_000213"
     CDS             complement(11238..11792)
                     /locus_tag="ACHDPO_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFN3367881.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(11918..13847)
                     /locus_tag="ACHDPO_000214"
                     /pseudo
     CDS             complement(11918..13847)
                     /locus_tag="ACHDPO_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(14153..14869)
                     /locus_tag="ACHDPO_000215"
     CDS             complement(14153..14869)
                     /locus_tag="ACHDPO_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFN3367882.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="ACHDPO_000216"
     CDS             complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="ACHDPO_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFN3367883.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="ACHDPO_000217"
     CDS             complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="ACHDPO_000217"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFN3367884.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(18339..19799)
                     /locus_tag="ACHDPO_000218"
     CDS             complement(18339..19799)
                     /locus_tag="ACHDPO_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3367885.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(19789..21084)
                     /locus_tag="ACHDPO_000219"
     CDS             complement(19789..21084)
                     /locus_tag="ACHDPO_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFN3367886.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(21416..22093)
                     /locus_tag="ACHDPO_000220"
     CDS             complement(21416..22093)
                     /locus_tag="ACHDPO_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFN3367887.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22123..23214)
                     /locus_tag="ACHDPO_000221"
     CDS             complement(22123..23214)
                     /locus_tag="ACHDPO_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFN3367888.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(23315..23749)
                     /locus_tag="ACHDPO_000222"
     CDS             complement(23315..23749)
                     /locus_tag="ACHDPO_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFN3367889.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(24333..25790)
                     /locus_tag="ACHDPO_000223"
     CDS             complement(24333..25790)
                     /locus_tag="ACHDPO_000223"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFN3367890.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(25787..27682)
                     /locus_tag="ACHDPO_000224"
     CDS             complement(25787..27682)
                     /locus_tag="ACHDPO_000224"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFN3367891.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(27740..29515)
                     /locus_tag="ACHDPO_000225"
     CDS             complement(27740..29515)
                     /locus_tag="ACHDPO_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFN3367892.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(29565..31061)
                     /locus_tag="ACHDPO_000226"
     CDS             complement(29565..31061)
                     /locus_tag="ACHDPO_000226"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFN3367893.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(31255..32877)
                     /locus_tag="ACHDPO_000227"
     CDS             complement(31255..32877)
                     /locus_tag="ACHDPO_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFN3367894.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(33205..34518)
                     /locus_tag="ACHDPO_000228"
     CDS             complement(33205..34518)
                     /locus_tag="ACHDPO_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFN3367895.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(34763..34987)
                     /locus_tag="ACHDPO_000229"
     CDS             complement(34763..34987)
                     /locus_tag="ACHDPO_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367896.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35007..35429)
                     /locus_tag="ACHDPO_000230"
     CDS             complement(35007..35429)
                     /locus_tag="ACHDPO_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFN3367897.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(35571..36281)
                     /locus_tag="ACHDPO_000231"
     CDS             complement(35571..36281)
                     /locus_tag="ACHDPO_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFN3367898.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(36299..36796)
                     /locus_tag="ACHDPO_000232"
     CDS             complement(36299..36796)
                     /locus_tag="ACHDPO_000232"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3367899.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(36833..37285)
                     /locus_tag="ACHDPO_000233"
     CDS             complement(36833..37285)
                     /locus_tag="ACHDPO_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFN3367900.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(37420..38025)
                     /locus_tag="ACHDPO_000234"
     CDS             complement(37420..38025)
                     /locus_tag="ACHDPO_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFN3367901.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(38475..39095)
                     /locus_tag="ACHDPO_000235"
     CDS             complement(38475..39095)
                     /locus_tag="ACHDPO_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3367902.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39097..39966)
                     /locus_tag="ACHDPO_000236"
     CDS             complement(39097..39966)
                     /locus_tag="ACHDPO_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFN3367903.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(39989..40396)
                     /locus_tag="ACHDPO_000237"
     CDS             complement(39989..40396)
                     /locus_tag="ACHDPO_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFN3367904.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(40415..41704)
                     /locus_tag="ACHDPO_000238"
     CDS             complement(40415..41704)
                     /locus_tag="ACHDPO_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFN3367905.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            41762..43101
                     /locus_tag="ACHDPO_000239"
     CDS             join(41762..42203,42203..43101)
                     /locus_tag="ACHDPO_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFN3367906.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
     gene            43221..43394
                     /locus_tag="ACHDPO_000240"
     CDS             43221..43394
                     /locus_tag="ACHDPO_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367907.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
     gene            complement(43460..44068)
                     /locus_tag="ACHDPO_000241"
     CDS             complement(43460..44068)
                     /locus_tag="ACHDPO_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HFN3367908.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(44074..45102)
                     /gene="vanB"
                     /locus_tag="ACHDPO_000242"
     CDS             complement(44074..45102)
                     /gene="vanB"
                     /locus_tag="ACHDPO_000242"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HFN3367909.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            complement(45095..46066)
                     /locus_tag="ACHDPO_000243"
     CDS             complement(45095..46066)
                     /locus_tag="ACHDPO_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HFN3367910.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            complement(46063..46770)
                     /locus_tag="ACHDPO_000244"
     CDS             complement(46063..46770)
                     /locus_tag="ACHDPO_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HFN3367911.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            complement(46788..47594)
                     /locus_tag="ACHDPO_000245"
     CDS             complement(46788..47594)
                     /locus_tag="ACHDPO_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HFN3367912.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            47873..49174
                     /locus_tag="ACHDPO_000246"
     CDS             47873..49174
                     /locus_tag="ACHDPO_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFN3367913.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(49265..50626)
                     /gene="vanS-B"
                     /locus_tag="ACHDPO_000247"
     CDS             complement(49265..50626)
                     /gene="vanS-B"
                     /locus_tag="ACHDPO_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HFN3367914.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(50629..51288)
                     /gene="vanR-B"
                     /locus_tag="ACHDPO_000248"
     CDS             complement(50629..51288)
                     /gene="vanR-B"
                     /locus_tag="ACHDPO_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
                     /protein_id="HFN3367915.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            complement(51906..52073)
                     /locus_tag="ACHDPO_000249"
     CDS             complement(51906..52073)
                     /locus_tag="ACHDPO_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367916.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            complement(52231..52416)
                     /locus_tag="ACHDPO_000250"
     CDS             complement(52231..52416)
                     /locus_tag="ACHDPO_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFN3367917.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            52561..52931
                     /locus_tag="ACHDPO_000251"
                     /pseudo
     CDS             52561..52931
                     /locus_tag="ACHDPO_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            53189..53518
                     /gene="mobC"
                     /locus_tag="ACHDPO_000252"
     CDS             53189..53518
                     /gene="mobC"
                     /locus_tag="ACHDPO_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFN3367918.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            53479..54807
                     /locus_tag="ACHDPO_000253"
     CDS             53479..54807
                     /locus_tag="ACHDPO_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFN3367919.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            54804..55175
                     /locus_tag="ACHDPO_000254"
     CDS             54804..55175
                     /locus_tag="ACHDPO_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HFN3367920.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            55358..55594
                     /locus_tag="ACHDPO_000255"
     CDS             55358..55594
                     /locus_tag="ACHDPO_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3367921.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(55894..56097)
                     /locus_tag="ACHDPO_000256"
     CDS             complement(55894..56097)
                     /locus_tag="ACHDPO_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HFN3367922.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(56101..57045)
                     /locus_tag="ACHDPO_000257"
     CDS             complement(56101..57045)
                     /locus_tag="ACHDPO_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367923.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            complement(57046..60966)
                     /locus_tag="ACHDPO_000258"
     CDS             complement(57046..60966)
                     /locus_tag="ACHDPO_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodL domain-containing protein"
                     /protein_id="HFN3367924.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            complement(61115..63196)
                     /locus_tag="ACHDPO_000259"
     CDS             complement(61115..63196)
                     /locus_tag="ACHDPO_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFN3367925.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            complement(63193..64422)
                     /locus_tag="ACHDPO_000260"
     CDS             complement(63193..64422)
                     /locus_tag="ACHDPO_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1107 family mobile element protein"
                     /protein_id="HFN3367926.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            complement(64412..64663)
                     /locus_tag="ACHDPO_000261"
     CDS             complement(64412..64663)
                     /locus_tag="ACHDPO_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HFN3367927.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            complement(64686..66677)
                     /locus_tag="ACHDPO_000262"
     CDS             complement(64686..66677)
                     /locus_tag="ACHDPO_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFN3367928.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            complement(66709..69108)
                     /locus_tag="ACHDPO_000263"
     CDS             complement(66709..69108)
                     /locus_tag="ACHDPO_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HFN3367929.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            complement(69038..69460)
                     /locus_tag="ACHDPO_000264"
     CDS             complement(69038..69460)
                     /locus_tag="ACHDPO_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HFN3367930.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            complement(69474..70010)
                     /locus_tag="ACHDPO_000265"
     CDS             complement(69474..70010)
                     /locus_tag="ACHDPO_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MT-A70 family methyltransferase"
                     /protein_id="HFN3367931.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            complement(70047..70910)
                     /locus_tag="ACHDPO_000266"
     CDS             complement(70047..70910)
                     /locus_tag="ACHDPO_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HFN3367932.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            complement(71002..71217)
                     /locus_tag="ACHDPO_000267"
     CDS             complement(71002..71217)
                     /locus_tag="ACHDPO_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family mobile element protein"
                     /protein_id="HFN3367933.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            complement(71294..73102)
                     /locus_tag="ACHDPO_000268"
     CDS             complement(71294..73102)
                     /locus_tag="ACHDPO_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFN3367934.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            complement(73099..73575)
                     /locus_tag="ACHDPO_000269"
     CDS             complement(73099..73575)
                     /locus_tag="ACHDPO_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HFN3367935.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            complement(73650..73862)
                     /locus_tag="ACHDPO_000270"
     CDS             complement(73650..73862)
                     /locus_tag="ACHDPO_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFN3367936.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            complement(73884..74849)
                     /locus_tag="ACHDPO_000271"
     CDS             complement(73884..74849)
                     /locus_tag="ACHDPO_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HFN3367937.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            complement(75337..76014)
                     /locus_tag="ACHDPO_000272"
     CDS             complement(75337..76014)
                     /locus_tag="ACHDPO_000272"
                     /inference="COORDINATES: protein motif:HMM:NF024685.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFN3367938.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPHY
                     CIMRKIL"
     gene            complement(76047..76898)
                     /locus_tag="ACHDPO_000273"
     CDS             complement(76047..76898)
                     /locus_tag="ACHDPO_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFN3367939.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            complement(77054..77299)
                     /locus_tag="ACHDPO_000274"
     CDS             complement(77054..77299)
                     /locus_tag="ACHDPO_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3367940.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            77404..78177
                     /locus_tag="ACHDPO_000275"
     CDS             77404..78177
                     /locus_tag="ACHDPO_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367941.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            complement(78230..78544)
                     /locus_tag="ACHDPO_000276"
     CDS             complement(78230..78544)
                     /locus_tag="ACHDPO_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367942.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
BASE COUNT        20825 a        18563 c        16017 g        24055 t
ORIGIN      
        1 ttttattgaa cttaaggttg attgatcaca tctaaaagcg ttgaaaataa aatggcacta
       61 gaagcagctc ctgggtcgat atgtccgatt gcacgctctc ctagatagga agctcgtcct
      121 tttttagcta ccaagacttt ggtgtgttct tttgcctggt caatgatttc ttttgttaaa
      181 ttccctgcct tcaatgcctc tgtgactggc agccaaacat ctaacatcgt tttatcgtca
      241 gcttctgcct ttcctcggct ttgaataccc gctgttccct gctcgatcac ttcgcctaat
      301 ttttcttgag aatcaataga atcgacctct tttgtcgctt tcatcatgtt catgaatgca
      361 gatccgtata acggaccaga agccccaccg actttcgata tcatcgccat agagaatact
      421 ttgaatgtat cgctgattgt ttcaggatga tcggcttgaa aagcttcttc ataagctgaa
      481 acccctcttc ccatgttatt tccatggtct ccatcgccaa tcggggtatc tagatcactg
      541 agatattgtt tgttctgatt gattgcctct gcaaattgcg tgagccattc ttggatttct
      601 tgaacggtta gtttcatatt atcacccttt tatcttgaga ttttttacca tgaaatcgtc
      661 tgtacattgc tttctaaaga atctttccat tgtgtctccg tcaagtcgat cagtgttaga
      721 gaaagacctt gcatatctag tgaggtcata aaattaccga cttttcggaa aactacattg
      781 acgcctcttt cttccaacag agctaaaaca tcattcatga acacgaactg ttccatcaaa
      841 ggcgtcccgc ccattccgtt gactagtaca cctgcttctt ttggtaaatt cgagtaatca
      901 tctaaaatct tagtaacaag ttcctttgcc agtactttag aaggctgcat cttttctcga
      961 cgatagcctg gctcaccgtg gataccaaca ccatactcga tctcatcttc tcctagttcg
     1021 aatcctggtt tccctacttc tggtacagtt gctgctcgaa gcgctagacc gatcgtctta
     1081 gttgcctgta cgaccttttc tcccagttct ttcaactcag ctagggaagc accgtttctt
     1141 gctgcatcgc ccacgatttt gtgtacaagg acagtacctg caactccgcg ttttccagca
     1201 gtatacgtac tattttcaac ggcgatatca tcatctacga tcacactttc tacttcaata
     1261 tcgtccatag cagctaattc ctttgccata tcgaagttca atgcatcccc tgtataattc
     1321 ttaacgatca gcaaaactcc ttttccacta tcggcttcct taatagccgt ctgaatctga
     1381 tctggagttg gagaagtaaa cacatcacca agcaccgctg cacttaacat cccttcccct
     1441 acaaacccgg catgggatgg ttcatgtccg cttcctccac cagaaaccaa accaacttgt
     1501 tccgctttct gattcttggc tacaacacgg gaagattcta cacgatgaac aagttctgga
     1561 tagcttttta ctaatccttc cagcatttct tcgacaatat tgcttggatc attcatgatt
     1621 tttttcaatt tattcccatc ctttctttcc ggcattttgt gcttctgtta agatttgctg
     1681 agtatcatct gttataccgg cagtgatggc tgctgcaaaa gctccttcca ctaaaggcgc
     1741 atccaccaga tgataacgtt gctgctgctc ttcttccaac atgtcttttg ccagttccga
     1801 gttcaatacc gcgctaccga tatccgcaaa aacaaaataa ctagctgcat cgcttgattc
     1861 attgactgct tctacgattt tcatcgggtc tgatccgatc tcgccattta ttccgccgag
     1921 agaaaaaatt tgcacctctt cggatttttg catctgctca atcatttctt taataccatc
     1981 tgttactttt tgactatgag aaataagcaa aatacttttt ttcacaagaa tcttcctttc
     2041 ttttacatag ttgctaacga ttggtttcgc tttcattaat gaacaattca agtatataat
     2101 aaatttctaa ttttgggaaa atatgtgtag tgcttcttga agtttgttat actttaatta
     2161 aaagagagga gtgatcgaat gattacaaca acaacgaaca gtgtagaggg aaaagccgta
     2221 gtagcttata aagggatcgt ttttggtgag gtcattactg ggatccatgc atttaaagac
     2281 ttggaggcgg ggttgcgaaa tatctttggc ggccgctcaa aaagctatga aaacgaacta
     2341 atgggtgcaa gagaagaagc acttgccgaa atggccgaac gtgcaaaagc attaggagct
     2401 gatgcgatca ttggcgtaaa aatggactat gaagtattag gcagcgacaa tggcatgctg
     2461 atggtcacat gtagtggaac agctgtctcc acgagataag taggggacat ctgttttaat
     2521 aactaaagag agatgggaca tgtagtggca ctcaagaatt agatttttca gtctaacttc
     2581 gaggtactct accttcccat cctctctttt ttatttcttt ttgcggatga ttccgtaagc
     2641 tgctgcgact aacacacccg cccctgctaa ggaataactg acagaagctg ttttttcatt
     2701 tgtttttggc aaagtctgac ttgttgattt ggatggctct gtcgtttgct gaactgtttc
     2761 tgtcgtgctt ccagaggtca ctgatttttc tcctgccgaa tgcaaaatat cttttattcg
     2821 ttggaaacta gctgctaagt cagctttttt tgcttcaaaa tcattagcaa ctgtttgtgc
     2881 ttcgctgatc tttccgtgga ttgcttgact ggccgctgtg atatccgctt gagtttgact
     2941 tagctttcca gaagctgttt gagcaacctg atttaattgc tgattgaatt cttttgcttg
     3001 ttggatcttc ccgtcaagat ctgtttggac agcttccgct tttgctttcg cttcggcaag
     3061 ctttttctca agttgtgcac ggtcatttcc cactttattt ttaagatcag ctaaatcttg
     3121 atcgattgct gcttggtctt ctttcaattt gttttttgca gcttctaatg cttcttcgag
     3181 ttcttttctt ttattttcca agtcttgcaa atgatcgatt tggtcagaag aggtagaact
     3241 atttattgat gtatcttctg aagatgaaat cgtttctcct gaattatctg tcggtacatt
     3301 ggaagtcatt tctgtttccg aggcaccgtt ttcagcacca gaagagctta tggttgttga
     3361 aggttctgtt tgagcaggtt cagaagtttc cgcaaaagct gtctgtccca ataagaaaat
     3421 actggaaaca gcaattggcc agattaacgg cttcattctt tttttcatca cttttcccat
     3481 ccttactact ttttaactaa tttcttatta taagcaaaaa tgtttggaag aaccataaac
     3541 acaacaggct gtttgtctaa aaaacggtgc atcttttatt tttttgtacg ttccgggctt
     3601 ttccatgtcc cgcttccata acctaaaatc gttttgactg ctggaatgaa agtcgtcacg
     3661 atcgttatcg cgttcactat ccagaacaaa agcatatata gtggtgcgaa aagaaggtat
     3721 ttcaattttc ttcgtcgatc atctacaatc agcgaagcta gcaactggaa aaatcctgcg
     3781 accatttcaa agcagatgaa cacaaaactg aatgtaaaag taatataaat ctgttcgtag
     3841 tttccttgat atacataatg cccgattaat ccagcaaaaa gaactacgga aatacaaaag
     3901 aatattgacc agacaatact caatgtttga tcaatgaaga tgatcgttct tccaatatgt
     3961 ttaaaaggat ggagcatcac ttttttgaaa ttcgtcagcc agacttctgt tccacctttt
     4021 gcccaacgtt ttctgtgtcg atatagcatc ttcaacgtca caggtacttc catgaaaaag
     4081 ataatctcag gagcaaaaac agataaccag tcatttaact gatgatccca agcaatactg
     4141 atgtcttctg tcgctcgatc ttgtctgaat ccgcccacat cgatcaaggc ttcttttcga
     4201 tacatcgtat ttgctccact gtacgcataa agaccaccga aaacagctga ctgtgttcgt
     4261 ttaatgatgc ccacgatact tgagaattca accgtttgag attttgcaat caatttggta
     4321 cgattttgga catccatatt tgcagtgacc gcagcaatat gtcttgcacc agggcgaatg
     4381 aaataattca catacctaat cagtgcatct ggctccggta ccgtgtctgc atcattgctt
     4441 aaaatcaatt tcccttttgc aaaggcaagt ccgatattaa acgcgtgggc ttttccttta
     4501 tttttttcga tccgaaccac acgaagatta gcgtattttt tcatcagtct agctaatatt
     4561 tctggtgttt ggtccgttga accatcgtct gtcactaata cctcatagtt gtgataattc
     4621 aatttcgtca tcaaatactc gattgtatat tcgatcacaa tttcttcatt atgggctggc
     4681 accatgatcg tgatgaacgg ttcgacactc aagggaacat ctacccattc tttttgctta
     4741 tgtttgtata aaaacacata acaccagaca ccaataaacc atacaaatcc gcctaaaatc
     4801 ggataagaaa cgagaaaaaa atacataata gacaaacaag tatctaagaa taaattacct
     4861 gtatgggtga ttgagatcat ttcagttcca ccccattttc tttatacaaa tctgcaatga
     4921 atgtcgtatc tagatttttc tcttcggaga cagaataaaa acggaccgtt tctctctctt
     4981 cttttgttcc aaaacgttcc gtatacactt cttcaagtaa ttcttgtctt tttttcaatt
     5041 tttcatcttc atattcaaaa gatttattta cttttttgta tagatttcga ttgttccacc
     5101 tagtcaatac aaatgaggta atcaggaaac tgaaaaaaat caatacaaaa aagccgatta
     5161 agaaatacag cattttcttt tctgataaaa aagcgtacaa ggaaaaatcc ttggctcttt
     5221 ctggtctcgt taatgggaaa aagacccata taaaaggaag aacaacgatc atccatccta
     5281 aaagagccac taacgtttgc caaatcttta accagtaatt accttttgaa aaatacttat
     5341 ctttcaccaa aattgatgca acttcttctc ttgttacttt tttcatatcc tcacctcacg
     5401 tttttttgtt acgacgtagg agtttaccac acatttcatt tcttttcaca taaagtgttc
     5461 ctaaattttt cctaagaaaa agaacaaaac atttctcatc agcaaatgaa aaatattttg
     5521 ttctttttat cagttgttct ttttattttt tatctcttaa ttatgttgct ctttccaata
     5581 cgacaatgct tttcattcct ctagatatcg ccgtgtacat ttgtctgcgt cttctttgct
     5641 catctccatc gttttcaaat ggatataaga ttacatgatc aaattccagt ccttttgcta
     5701 gactcaaagg aatgatttgg cagttttcta atccatatga atttttttta atcgattctt
     5761 gtagcgtttg ggtttcctct tctgtttggg tgataactgc cgctttttct ccttttagag
     5821 aaaccaaaat ctcagctagt attttcaaca attcttcaga ggatcgaaaa gagcggtatt
     5881 cgggttcttt tccttgcggt cggatcgata cgatgtcgat cttctcttga tccacagcat
     5941 aggttttgaa aagctctgtg attgctccgc tagaacggta actatttcta agatcatacc
     6001 gatggatcgg cagatggtag tcgtcgaaac aacgcataat atcagcaaaa gtagtggaag
     6061 aattaaagat tgcctgattc tcgtcaccta ctaaagtaaa gtgagttttt ggaaataatt
     6121 cgatcaatag acctaattgt gccagggtat aatcttgtac ttcatcaatc aatagatagc
     6181 gaaatgctgg tacatttacc ttttcaacaa gtaaatgacg aatagctaat ataatgactg
     6241 cttcatcaac agtacgtgtg ggttgccaag cataagctga gccatatcgt ttttcataaa
     6301 ttctttcaaa caactgatgc tcatccaccc atgccatttc ttcgatttgt ctggttattt
     6361 ttcgatattt tttttgtaaa agtttccttg cataagctac aatactttgt tccgaatcat
     6421 cagaaatcaa tttaccgaat aattccaact gcctatcttc tgtcaacgag agtacctgat
     6481 tctgcacagc aggacttttt gcttgtttca aaagatgatt cttccattcg ctcatcagtg
     6541 cctttttcgt tgcttgaagc ctatcgatca atttaggatg agcaggaact ttctcatata
     6601 ttttttcgat cgttttttta gaaaggactg tttttccatt tttagtaagt ccacggataa
     6661 aattcggatg atctaaaaac aaaggatctg attgttttag attatcgata aactttttgc
     6721 tacgcaaacg ttctgtctgc tccgatacat tttctcccgt gatacgtttg aaataagcct
     6781 cttcaccttc tatttcctct gctgaaagct gtgaaaccag ctgtatgatg gttagattca
     6841 gtggatttct ttcacctaat gatggtagga cattcgaaat atagtcgata aaccgatgat
     6901 taggtgatag aatcagcaag tcatcggatg tcatcgtatc tcgatataaa tagagcagat
     6961 acgcaatacg ctgcatgata gcagaggttt taccacttcc tgctacgcca tttaccaaga
     7021 tattttgact tttcacatcc cgaatgattg tgttttgttc cgattggatc gtagcagtga
     7081 tagccttcat ttcattggtc tcatcttggc ctaagacttc taataatacg tcatcttgaa
     7141 tagctacaga cgtatcaaaa aacttgacca aacgatctct ttccaaaaga aattgtcgtc
     7201 tttctttaat aaccgtatcg attttatttt gacgaaccgt ataagaagat ggaccaatca
     7261 tgttattgta aaaaagttcg gcaattggtg aacgccaatc ataaacaaga ttttcatctg
     7321 catcatctgt gaaatttgct gtaccgatat aaaaggattc ttttggctca ttatccagaa
     7381 agtctacaac gacttttcca aagtagggac ttttcaataa acgttcgatc tttgctagct
     7441 gattttctgc gtttttctgt ttgatattca tctgatcgat ttctctattt ttcatttcaa
     7501 tcatcgaaaa agtatccagg ttatctaagt aactgtcaaa attcaatcga agctcgccag
     7561 ccatttcttt caacgactgg tttccttcta tttttgccgt atccatcgat tcccgcagtt
     7621 cgtttttttt atcaattagc ttttgataca cgttcttcag atatgcttct tctaactgtt
     7681 tttgtgtgtt gaccatacac attctcctct ttttttaaag tggtggaacc gattagttta
     7741 cctcttttaa gagtcgaatg caagcttttt aacgagtatc atttgttagg atatatcagt
     7801 tcttcaggtc ggacagtttg atataaagaa aatgcaccat caaggttttt tacgtggtag
     7861 ccagactgct tcaagattct ttccgctaga tagctacgta atccgctatg acagctgacg
     7921 atatattctt gttggctgtc taattcattt aatcggtccc gaagttcatt caaagggata
     7981 tgtttggctt ccttgaattt gcccttttcc aattcttctg ctgttcgcac atctaataaa
     8041 atttttcctt ttgctagttc tgtcggcaat tcatgccatt gtacggtttc actaagccct
     8101 tctgcaatgt tcattgctgc atatcctagc atgtttactg gatctttggc tgagccaaat
     8161 ggcggtgcat acgtcaattc taattccggt aaatcgaaga tcgtcaaatg ccctttgatt
     8221 gctgttgcta aaatatcgat ccgtttatcc acaccttttg ccccaacacc ttgtgcacca
     8281 taaatctcgc cagtctctgg atggaagatc aacttcagta aaatatctgt tgcttctgga
     8341 taatagcttg catgatcttt tcctgataca tgaatgactt caaaagacag ttcgttttct
     8401 ttggctgttc tttcacttaa accggtggat gcggcagtca ttccaaacgt tcgtataatt
     8461 gctgttccaa taccgccttg atttcttcga gaaattccgg aaatcgtgtc cgcaacttgt
     8521 ctaccttgac gattggctgg tgaagcaaga gaaataagtg catcttttcc agtgatttgc
     8581 tgttttacaa cgatagcatc ccccaccgca taaatatcag gaatattcgt ttgataacgt
     8641 tcgtctacta ggataccccc gcgtatgcct aattcgattc cagcggtcac tgctagctgg
     8701 ttatcaggac gaacaccaat ggataaaata actaaatcag cagggatggt acgcccatca
     8761 tccagtcgca atcgtttccc gtggtcttca aatccagcga cagcatgaga agtaatcact
     8821 tctactcctt gatgagacaa ttctttttct ataaaagctg ccatttcttc atccagtgtt
     8881 ggaagaatat gtggtgcttg ttcgatcacc atgacttcta aacctcttct ttttaggttt
     8941 tctgccattt ccaatccgat gaatcctgca ccaacgatca cggcacgctt tggctgtttt
     9001 tctaatgcat gcatcacttt atcgatatct ggtacatttc taatagaaaa aacattgtcg
     9061 gcttctgtta tccctggaat cgatggaaca actggttttg caccaggaga taaaaccaat
     9121 gcatcgtact gttcaatgtg tttttgaccc tcatgtacga cttctaccgt tttgttttcg
     9181 ggaaagatgg ctgtcacttc atgatttgga cgcacatcta aacaaaaacg agcggataat
     9241 gattctggcg tttggacaag aagattttcc cgttcactga tttctcccga aagataataa
     9301 ggcaagccgc aatttgcaaa agaaacatac ggtccttttt caaaaacaac gatttctgca
     9361 tcttccatta atcggcgaag ccgtgtagca gcagacattc cacctgctac acctccgaca
     9421 ataacgattt tcatcttatt tccctcctac tgttcgatca aaccattgat tcatgccacc
     9481 acgtacattc actacatcat aaccagattt ctttaattct ttagctgctt gtttactcct
     9541 catccctgat tgacaaatca catagacggt cttttctttg tctccatcat atctgtttat
     9601 actttgtaat ggaacatttt tagctccttt tatatgcccg ccccggtatt ctgcaggtgt
     9661 tctaacatca agtaacgctg gattttccaa aagcttttcc tttaattctg ggactgttat
     9721 cgattttatt gattgaaata gcaaattcat tttctgcacc tcatttacat ttttataaat
     9781 acctcatggg gtatattaaa caggagcttt attaatatgt caaccagaat gactcttcat
     9841 ttttttcact actttttata tttgcataaa ataccgataa ggggtattat ctaattataa
     9901 aaatagagga gaatgtgtta tggagattga taataaaaat atcctgaacc gtttgaaacg
     9961 tacagaggga caaattcgtg gtatccaaaa aatgatcgaa gacgaaaaag aatgtatgga
    10021 tgtcatcact caattaagcg ctgttcgttc tagtattgat cgcgtaatgg gcatgatcgt
    10081 tgcagataat ctgaaaaatt gctttgagaa acctgatagt aatccagaag aacaagcggc
    10141 taaactagaa caagcgatca agatgattat taaaaagtaa aggaatgatt tcaatgaaag
    10201 tcgttttcca tattgatgaa ttagaaaaat ggtcagaaac agggaaaaac gtaaaaaacc
    10261 tgataaaagc ttctccagaa acgacgattg tcgtatctgt aaatggcatc gcgattaccg
    10321 gttatctaga ctctgccaat gcagaattct tagatttgca aggagtcgtt tttcacgctt
    10381 gcgccaatgc tatgcgtgct aatcatattt cagaaagttc tttacctgaa caagtaatcg
    10441 ttgtaccagc aggtgtcctt gatttagttg aactgcaatc ccaaggttat gcttatatca
    10501 agccttagtc agtagaggtt gcgacagaag tgatcagctt caagaaattt cggcttattt
    10561 ttcgaagaag ctacttctgg aaaaccgtga atcaaaggtt gtgaaaacgc tgtcctgcat
    10621 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcgtttg gttgggctta
    10681 ttaccgcaga tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa tcagcggttt
    10741 gacctaagta ttagagaaaa aaacgggaaa atagctcctc atattttgcc gttttttgag
    10801 ctaataccga aggtcagctg attgaacacc gtttaaggaa gagattgtga aaaagtcgct
    10861 tagtttcgag tattaagaaa aattttgtga aaatggattt ctacattttt gcataaattt
    10921 ggcttaatac cgagaaactg gcttttgaat accgtttaag gaagaggttg taaaatcagc
    10981 ggtttgacct gagtattaga gaaacaaacg gaaaaatagc tgctcatatt ttgccgtttt
    11041 ttgagctaat accgaaggtc agctgattga acaccgttta ccaagaggtt gtgagcctac
    11101 catttaactc cgaatcacaa gaaataattt caaaaacaac ttctcctgtt tttggttcgg
    11161 ttggcttatt atcgagaagt agctactggg agtctattta tcaaaaaaag gaatgcgaca
    11221 taggtcacac ccctttttta ttttctttga aacatctttc ggtactcgac agcatacaag
    11281 acaaaagatt gtaaaagacc gtaagtgatg acggcaaaaa tgactctcac ccacagcgtt
    11341 ggtaattctg ggaaaagcag caaaaggatc atgccaacat agatgacagc agtcgctact
    11401 ttgccatacc acttcgctcc acttaatttg atatttttag atagcccgat taatccagct
    11461 acaaacataa agccttcttt tatcaagaat agaccaaaca acagccaaag ccacggtcga
    11521 taccatgcca tagacaaaat cagaaaaagt tgtgtcaatt tatctgcaaa cggatcaagc
    11581 accttcccta agtctgttac ctgattatat ctccgagcaa tgaccccgtc tagataatca
    11641 gacaaacctg agacaacaat gaccgctcct gctatataaa atgactgtct cagcacaaaa
    11701 taaagataaa tcggcagcaa aaaaatacgg aatatcgata aaagattcgg aatcgtttgt
    11761 atttctttac gccagtctgt gcttaatttc attttatcgc cctacctcct cagcactctt
    11821 ttctttttat tttagcttac acggggaata aaaccaatga tttcactgtt tttatttttc
    11881 tttacagaca ctgatattat gagctaattt gagataatca cttgctgttt tcatcgttta
    11941 ctcttctttc ttcctgtcgt ttgcgcattt cttttactag tactttatga gctttttttg
    12001 atcctcgctc taggtcacgc tgccgtttac gtgttttata atcgataaac agactgtcta
    12061 aatcgtaacc tgtcgggtac agatcttctg ctgaacgcac cagacgaaca cgctgacgag
    12121 gcacgtggat tatttttttg tctaaatata catcaatcgt atcttcacct atatcttcat
    12181 aaactaacgc ttctttttgg tattcattga caaatatccg atcacctttt gcaaagagct
    12241 gacgttcttt tttattctcc ttcctatttg taactgctgt cttaggaaga aattcttttt
    12301 tctgtgtccg ataggctttt tccgccaagt aacgctctgc ttgatggatc aatttcatcg
    12361 acatatccat tttatgagca atccacaaag cttggctttc tcctgtttct tccaacccgc
    12421 aactgatatt taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct
    12481 tcatgatctc cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc
    12541 ccttgctcat acatagattc catgattgcg atcgctagtg cagccccttc atttggctct
    12601 gttccactgc caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata
    12661 gcagcgatgt tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg
    12721 tcaccgacat cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga
    12781 acttgcatac cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt
    12841 ttgcctccgg catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca
    12901 tccaatggta ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt
    12961 tccgatttat tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca
    13021 aagatgatat ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct
    13081 gcgatagcac cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt
    13141 aacaactgat agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt
    13201 cttttatttg attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata
    13261 ggaatcgtat agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt
    13321 ttcggatgac gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat
    13381 tgtttgcgta ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt
    13441 ttctggtcaa tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac
    13501 aacaagggtg tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta
    13561 agaaaatccg catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt
    13621 tctgtcagtg catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag
    13681 atcaagcgtg cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag
    13741 accgtcatat cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc
    13801 tttttgatcc gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt
    13861 cttgaagaga tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac
    13921 acagcttaaa aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca
    13981 ggtaccgttt cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt
    14041 agataccagc tacactcaca aaacataccc cattcttcta ggtcttattt attttccact
    14101 taactatagc aagacacatt ttggttgtca aactttagta tgttttatag atttacacca
    14161 ttaatgaata gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc
    14221 atgaatatgc ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc
    14281 gaggaccaaa gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac
    14341 cgatggctaa gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt
    14401 gtccaaaagc tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat
    14461 ttgctggata attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat
    14521 ctttcgttgc attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag
    14581 ctcctaaaac ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca
    14641 tcgccatagc tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat
    14701 agacagccat tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct
    14761 gtgctttact tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga
    14821 tcagtgtccc aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc
    14881 cctttagttc ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg
    14941 ccttctcctc ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga
    15001 tctcatcaag ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc
    15061 ctggggccaa aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac
    15121 tcaaaccagg ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc
    15181 cgtaaaaatc agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt
    15241 ttgctaattc tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct
    15301 gatatttttt agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc
    15361 gtatcaatcg caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata
    15421 aagtcagcaa accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg
    15481 ctttttcatc acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa
    15541 ctttgttttc cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa
    15601 tcgatccatt atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa
    15661 gtcctgccca gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat
    15721 tgatcacatc caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc
    15781 cttggtaatc cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa
    15841 ccatccgccc atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt
    15901 tcgcatctac aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg
    15961 taaaattcaa gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg
    16021 ctttgatttc gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat
    16081 cgccatcata taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg
    16141 cagccttttt gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga
    16201 cacccgcgcc ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg
    16261 gtgtcagcgt ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt
    16321 ccattgctac tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg
    16381 gcaaaagcat tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt
    16441 caccaactgt gtcagctact acttccacat caaatgtctt cagataacga ataccgccat
    16501 gaacaagttt ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc
    16561 ctgttttgat tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac
    16621 cgatgatcaa cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct
    16681 tgtttgaaaa catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt
    16741 ttccaaccgt tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg
    16801 ccagcttcat aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct
    16861 gctaaaaatg ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca
    16921 ttcaagatat ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact
    16981 ttcaatacag gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact
    17041 tgataagcaa tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc
    17101 aagccaaaca tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat
    17161 gcaggaacaa cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg
    17221 ctagcttttt gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca
    17281 aaaatacttc cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc
    17341 aataaattat ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct
    17401 gtaccataag tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct
    17461 tgctggtctc ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc
    17521 gtataaccat aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt
    17581 agtaaatcta aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga
    17641 ctggcattcg agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa
    17701 gaatcgatcg ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca
    17761 tgatcaagaa tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt
    17821 ttttcgtgga aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac
    17881 tgtctggatt gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt
    17941 actgttgttt cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct
    18001 gattcgatga acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca
    18061 tgttccaccc aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg
    18121 tgtcttcctt tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc
    18181 atgatatacg ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa
    18241 ctactcttat catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc
    18301 tttttttgac agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc
    18361 gtctctattc ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa
    18421 tattcacact gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct
    18481 tcttcataac ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt
    18541 tgaaaagcaa tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt
    18601 gcaatataaa aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc
    18661 tcactatctt cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc
    18721 agtaactgtg ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc
    18781 tcatagactt cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg
    18841 tagcctactg ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc
    18901 gtttcccgaa tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca
    18961 tactgataaa atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc
    19021 attgtttcgt atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga
    19081 tcgattgctt gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg
    19141 tacgtacttt tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt
    19201 gcttctgctg atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt
    19261 cttttttctg gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat
    19321 agttcataat aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt
    19381 tgtaatccaa attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac
    19441 tcactgatat taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa
    19501 tagacgagca tcttaaactt caagctttcc tgcaataaaa acaatagaat tttttccaaa
    19561 cttacatctt cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt
    19621 ttttccatca ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt
    19681 gacagttgga catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg
    19741 tttcgcaaaa tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata
    19801 ggcagtattc gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa
    19861 tagctcatgt tcttctaact gttcaaacgt ccatccttct tctactgcaa ttgtcagttg
    19921 gtcaagaagg tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc
    19981 agaatcaaat agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc
    20041 tacgtatcct gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac
    20101 gcttcctaag aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt
    20161 tgtctgtgag ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac
    20221 tagagaaaca tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat
    20281 cgcataaacg tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc
    20341 attcaatgtt aattgttctt cccacatctg attgtcggga cgagaatgat tagccagcaa
    20401 aacaagatca tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt
    20461 caaagacaca acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac
    20521 taacggttct gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta
    20581 aagatggatt tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc
    20641 tgcaccaata attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt
    20701 ttgtatcttt ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg
    20761 atttgaacca gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac
    20821 gacttttttt tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg
    20881 gtcagtcagt tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt
    20941 taatatcaaa ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata
    21001 tatttcactt gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga
    21061 cccgccgaca attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta
    21121 acttctcaat cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga
    21181 tgcagcagaa tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac
    21241 tagtggacct aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat
    21301 aaaagaaaaa aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa
    21361 aagacgagtt ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat
    21421 tctttaatgc ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg
    21481 taagaagccg cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg
    21541 ctcctttttc tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg
    21601 cttcctcttc ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag
    21661 actcatctgt aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt
    21721 catttcgata gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca
    21781 ttgttccgtg gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag
    21841 gacgtaaggt atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat
    21901 cgatttcatc catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac
    21961 tgacaaaatc tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac
    22021 ttaaccacaa acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga
    22081 tcaatacttt cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt
    22141 caagaaatta tataatgggc ttggcaaata aagctcttta tatgcttttt caaaaggttt
    22201 cgttacaaat tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat
    22261 catttgctgt ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg
    22321 attgcggatc ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac
    22381 ttcaagaatc gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa
    22441 tgaaacatgc agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc
    22501 ttcaaaacgg atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa
    22561 tggtttttta gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa
    22621 acgataacga ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga
    22681 gaaaaattgt tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga
    22741 ttcaatcgct ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc
    22801 actcattgct cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac
    22861 aggctgttct ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat
    22921 aatcgctttt gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat
    22981 ttcatcatga gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc
    23041 agcaccagta ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc
    23101 ttcggtgatc actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg
    23161 gttcttcaat tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat
    23221 tcctcccata attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat
    23281 tagttgtaca tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg
    23341 catcattcat tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg
    23401 actgatgaag ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg
    23461 taagataaac taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta
    23521 atttttcaac aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt
    23581 tttgtggtat tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca
    23641 gacctgtcct tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca
    23701 cgctaaagaa aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc
    23761 cattggcgta catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc
    23821 cgcctcctct gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt
    23881 tttcgacaaa actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt
    23941 ttgagtatga agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt
    24001 aataccgaaa aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct
    24061 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag
    24121 ctaatgccga tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg
    24181 aactccgagt cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg
    24241 acttgtgatc gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca
    24301 agacttttgt cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg
    24361 acttgtctgt accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg
    24421 tcatcttgat caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg
    24481 acgatatcaa tgcagcccca cgacgtataa ccaaataaat ctactccatc tttgatagct
    24541 tccttcatct gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt
    24601 ccatcttctt ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt
    24661 tgatacctat catataattg attcaaagca attctcaaac ccttaggatc aatctgccag
    24721 ccccattcac ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg
    24781 accccttccc aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa
    24841 acaaaatcaa cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg
    24901 acaccttttt cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca
    24961 tcactaaaga acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca
    25021 caagaatacg gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata
    25081 atttcatgac aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg
    25141 tatttcgctt gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg
    25201 tgatgtttta cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag
    25261 cgtttgaata ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat
    25321 ccaccatatt ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc
    25381 tcaatcccat attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca
    25441 ttgggtgttt cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag
    25501 catttaaaac ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca
    25561 tttccgtgtc ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc
    25621 tgatgcgtca tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat
    25681 gtatacacat cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga
    25741 ttggccgctg tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc
    25801 ctaaacttgc tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga
    25861 atctactact atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt
    25921 cttgcaaatc tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg
    25981 cactttgaaa gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct
    26041 ctgctccttc ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt
    26101 ccccgtttac agaactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta
    26161 aagatccact agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg
    26221 caggagtact taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga
    26281 aaagaaaagt tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa
    26341 caaatccttc accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag
    26401 caccggctcc tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt
    26461 aaaatggtcg tttatattta agagtcacac cataaacagc aggttcagtg attccaaata
    26521 atgctgtgat aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa
    26581 ataccccaag tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg
    26641 tatcacgacc gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc
    26701 caaaaatcac taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa
    26761 agttataaac agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac
    26821 ctacaactaa taaaataatt gggaccatca cgatgataca aatgaatggt gtcaataaat
    26881 ttcgaatact ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata
    26941 cagctaaaat tgctggaata accgtacttg tataccttgc tagaatcacg ggcatcccta
    27001 gaaatcgcaa ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg
    27061 ctgcaataac catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca
    27121 aaaatatagg caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc
    27181 ctgattcagt agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac
    27241 cacttcctgc caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag
    27301 agtttaaaat gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt
    27361 tcatttgttt ggataatacg tcatacactt catttactgc atttcctact acgacttgaa
    27421 acattcctcc agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat
    27481 ctgccttctt attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc
    27541 tgacattttc ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca
    27601 tttttacttc ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt
    27661 tcttagaaaa cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac
    27721 aatagtgtgt atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta
    27781 tatcgtttct cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat
    27841 gtataagtgg tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa
    27901 gacagcacaa caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga
    27961 ttagttgctg aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt
    28021 aatgatcaag cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa
    28081 tctgataaat ctcccaagat tcaaactcat ctagaacact aggtagataa atcaaatcat
    28141 cccactcaaa aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt
    28201 ttgattgatt tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca
    28261 tactttgttg aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa
    28321 tcagtatctc cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaacaaaat
    28381 aagcgctttc agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta
    28441 aataaatttc taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat
    28501 gtccggcatc catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat
    28561 ggaacaataa cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta
    28621 gattcttctc tatttctttg tttttttcat cattaatcat caaataattt aactctaata
    28681 gtcgattttc aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata
    28741 acttttttgt gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta
    28801 aaagttcttc tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct
    28861 ctcctgaaac aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg
    28921 gcatgatatt ggaaaaaatt gtactgattt gttgaggaaa ccttgcgtgt tggatcaccg
    28981 tttctgttcc aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta
    29041 gtccttttgt cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa
    29101 tcgtttttat ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt
    29161 gcatactgac ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat
    29221 ccatgctgga atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag
    29281 attcaattga ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct
    29341 cgtagatagc aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag
    29401 cttcagctaa ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt
    29461 ggagttgtcg tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg
    29521 aaaaacctct caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat
    29581 ctatattcaa ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct
    29641 tttttcaatc tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca
    29701 tatcgcttcc tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag
    29761 taaccaatga tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt
    29821 agatactcac aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt
    29881 ccaatgccat tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg
    29941 acataacgaa accctagagg atcaattggc caactccaag gttcgggaga tttttccttc
    30001 aaaaagggat tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt
    30061 ttatagacag cgctacgata ataactaaat gcaatataat ctgccgtgtt agcttgcaag
    30121 cactgttcgt ctccatctaa cattactggt gcacagtctt cttccttcca tgtcctgtaa
    30181 atataagctg gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta
    30241 aattgcagtg aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca
    30301 gaaaagctac acataatacc catcttagca tttggatcga ttttctttaa taattgagta
    30361 gcacgggcgt tcgctagaaa catatgatga caggcttgat aaatcacttt ttttgttagt
    30421 gtagcaatgg gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa
    30481 ggcatacgaa aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg
    30541 tagcgttcaa agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc
    30601 caccccccat actctcctac caatgctaag ggggtttcat aatgactaag agtaattact
    30661 ggctcgatat catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc
    30721 tcatttggct tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga
    30781 aaagctttta aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa
    30841 tcaatcgctt catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt
    30901 ttttcttcat tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc
    30961 acattaggta atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct
    31021 ccgccccata aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat
    31081 caacaatttc ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc
    31141 ggcagaagag aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa
    31201 atacataaga cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt
    31261 tacttccaac acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt
    31321 cagaggataa tttgacacaa taacccttaa agcttcacgt ggaatagtga acgtctgctt
    31381 ttcactggac atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc
    31441 aaagacatgc tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg
    31501 ttttctacgc aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa
    31561 cgcttcttct gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt
    31621 agtaaaccca gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc
    31681 tttcgccttg attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt
    31741 atacatattg attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt
    31801 catgcctaac tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat
    31861 agcaaacatc ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat
    31921 tcgcggaaga tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt
    31981 ttgccatttg gataatactt ttttcagttc agagatactc aagggtttca aatcccattt
    32041 gtctttgcct tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc
    32101 atttctttta ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc
    32161 aacagtcatc agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg
    32221 cagtttaggt ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac
    32281 gtccatacga aagcccccaa tacctttatc gatccagaaa ttcatcattt gataaatctc
    32341 ttggcgaacc tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag
    32401 aaaatattgc cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa
    32461 tctattaggc tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt
    32521 ttctttattt ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac
    32581 cagatccatg atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc
    32641 ttccatcgta ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc
    32701 atcattcgga gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag
    32761 ataatccaac ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg
    32821 aaaacttctt ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat
    32881 tttcctccta taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca
    32941 ctaaaaattg taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac
    33001 aaaaaaacag ctgaggaaat tccctcaact gttttttgaa aggattgatt tatgcaggga
    33061 agaatgctga tttcacaact tctttataaa cggtgttcac tcagctgtcc cttggtatta
    33121 gctcaaaaaa cggcaaaata taagaaacta ttttttcgtt tttttctcta atactcaggc
    33181 cagaacgctg atttcacaac ctctttattt cacattcaat atccacatga atcccacaaa
    33241 tacaaagaac agaccataca tgattggaga tacttctttt cctcttttag ctgctaacat
    33301 ggtaattgga tagaagataa aacctaatgc aatcccatct gaaatactat aagtcaaagg
    33361 catgccgatc aagatcaaga atgaagggat cgcaatctct aagtttcccc attcgatttg
    33421 tcgcaaagat tgtgccatca atactcctac cataatcaat gctggtgcag ttacttgtga
    33481 agtaacaact gatagtaatg gagaaaagaa caagcctaac aagaagaaaa tccctgtagt
    33541 aatagctgtg atacctgaac gtcctccaac ggcgatacca gctgatgatt ctacaaatgc
    33601 accaacagga gaagtaccaa ataaggaacc cgcaagcata gctgttgaat cagaagctaa
    33661 agctttccct acacgaggca tcttgttgtc tttcatgaaa cctgcttggt ttgctaatcc
    33721 aactaaagtt cctgctgtat caaagaaagt cacaagcaag aatgtcagca ctacgaccca
    33781 catttgaaga gaattgatgt cccctacatg ttttaatgca actaaaaatg ttggtttcaa
    33841 acttggtgct gcggcaacaa tttcagaagg cattggaatc aaacctgtga ccagacctaa
    33901 aatcgttgta gctgccatcc cgatgaagat gccacctggt acacgccgaa caagcaagat
    33961 agcagttacg actaatccaa aaatcgtcaa ccaagtagaa ccaacgttga gtgatcctaa
    34021 tcctactaat gtagattcat tcgaaacgat gatcccacct tcgctcagac caaggaaagc
    34081 gataaataga ccgataccgc cagaaatcgc atatttcaaa tctgctggga tcgcatcaat
    34141 gatcatttcc cgcagcttga agattgtgat caaaataaaa atcaaagaag caacgaatac
    34201 gccggctaat gctgtttccc atggaatccc cattcctaaa caaacagaat aagcaaaaaa
    34261 agcattgatc ccaagagcag gtgccgttcc aattggataa cgggctaata cccccattaa
    34321 aacacagccg atcgcactgg ctaatgcagt cgcagtaaac actgctcctt catccattcc
    34381 agaagcacct aatacagttg gatttacaaa taagatataa gccattgaga taaatgttgt
    34441 aaatcctgcc agtacctcac gttttaccgt ggtgttcaat ttttctattt cgaagtagga
    34501 aagtattttt tccttcatct tccatccccc taaatccgaa cattataaat aaagtccgtt
    34561 aaaatttcga tttattaata aaacaacgtg ttttatcata tactaaaaca aaacataagt
    34621 aaacaaaaaa ttcggatttt aagcaaaatc cgaacgttcc atctgattaa atccctttat
    34681 ctcaaagttc atgaacattc actttggatt acaagaattt ctttattgtg ttaataaagt
    34741 ttcttcattc tagtctcaaa aatcaatagt gtgatttgat tttaccattt cgtttctgtt
    34801 cttctttgat gaattctttt gtatcgacag gattcagatt atttagtccg ccaaaacctg
    34861 tatcgaccat ttttccccag ccttttgtct tcttttttcc tgatttgaga ttctttgctc
    34921 gaagcttctc actatgtttt gctcgccgat acttcaaata accttctaat cttcccatta
    34981 gatccactgt ttttcctcct ttttattcaa tcagacgact cagcttttcc tataacaaaa
    35041 taattgcctt cagggtcaga aaaattgaaa gtcaagatgc cattgttatc tgtgatttct
    35101 cctggttctt ccatgttctc gtagatagtt tcaaattcat ccgtaaaaaa tactaaagaa
    35161 ggcggtggtc ctaatacctc tggtgaaaac ttctgcacaa atacttttgg gaatacgcct
    35221 aattctaatt cttttgagat gctgagtaca atactcttaa attcttctgg caattcgatt
    35281 gtttcagaaa tttctgcacc aattttttct acaaagaatc ggcaaatcat ctctacgtca
    35341 ttgacataaa gcatcacacg tgttttttgt atcatcattt gacccttctt tctatttgat
    35401 tttctttcct gtctataaac tgattccatt atatcacgaa agcgcaaaca ccttgtgttt
    35461 gatactattc aagaaaaata aagcaatagt ttctaggatt gctttcctcc acaaactttt
    35521 tttacaaaaa aaaaacggca atgaatgccg ctcttcttat ttcgattctt ttataattct
    35581 gcttctgatt catctttggt tagtgtgtgt ctaacactag ttacgccaaa tgtttgatcg
    35641 attttttcct tcaacgcttc gattgcctgt gcgccacgtg ccgcttgttc agcattgatg
    35701 gattcaatga ccagcaccgc tgcttgtgtt tcttccgtca gcatcgttct ttgggcttca
    35761 cgccagttga gacagcgaca gatcgctcct tgttcatcat agtagatgat ttcttccgga
    35821 agtgccggag catcggaatc tgcacctaaa ggcaggaatg attcgccacc ttgggctttt
    35881 cctaaatgca gatttcctgc gatcttttcg atatcttctc cgccgcaagg tacgccaaaa
    35941 gacaaggaaa tactattata gatatctaca agcggattga ttgggaaaaa ttcccgttct
    36001 tgatttgcac gtttcagtaa agcttcaata gaagaacgtg cacctttttt agtcttgaat
    36061 gtggtaaatg cctgacgcca ctgagcaatg acttcgtttt ggctgaatgt ttcttctgta
    36121 aggtaatttc ttgcttcttt tgctgcctca ttcaataatt gatgatacgt ttcttcactt
    36181 tcttttgtta cgtggttatc gataccattt acggataaga tttcgatggt tgcttcagga
    36241 aatacttccc agaaattggt atccactatt acttttttca tctgttcaca cctcttgatt
    36301 agaataattg cttgatgaat agatagtctg tttggggatc atctcccata taaaaaacat
    36361 gttcgctgta tttgataaat ccttttttac gataaaaagc gagcgcaaca tcgttgtgtt
    36421 cccaaacacc gagccaaatg gctgtttttt gcttttcttt tgctttttca atagctgtat
    36481 ctagtaaaaa tgtaccgata ccttgatgtt taaatttttt tcgtacatag attcgctcga
    36541 tttctaaaaa atgatcagcc atttcctcag attgactcgt tcctgtattt agtttcaggt
    36601 aacccgcagg ctcttgatcg atactcacta ggaaaaaatc ggtttcttta tcttttagct
    36661 cttctgtaag tttttctagt gcataagctt gtgtcaagta atcagctaaa tgctccggtg
    36721 aattatcttt tccaaatgta tctgtaaatg tttcgatact aatttgttgt agtaagtcta
    36781 catctgaagg cgtcattttt cgaatttcgt atttattcac ggcttcttcc tttcaataga
    36841 tccttttatt gccttttttg acaaaattcc aatcttcgct aacattcttg catactttat
    36901 ttaaaagata ttccaattgt tttgcttctt cgtcagaaag accatttaat gcgactgcat
    36961 tggagtagtt gttttctcga atgatgaaag gatagatttc tgctcctttt ttagtcggat
    37021 agagtttctt gattttttta ttttctttat cttccaaacg ttcgatcatc ccattggatt
    37081 ctaatttctt gattgctcgg gcagtcgttg tacgatctac tttgatcatt tctgctagtt
    37141 tttcttggat gattccagga ttttcgcaaa tacgtactaa ataaagatac tgtcctcttg
    37201 ttaaatcgac ttctttgaat tcgatattgc taatagaatc tagcgctcgg gcaatcattc
    37261 cgatgtctcg aaggatttca gccatttcat cccaccttta ttttgtttgt aagactagtt
    37321 cacctctttt tgttgcaaat gcaactattt tcaataaaaa aatcaagttc ttttttaata
    37381 actagtaaag tatattcttt tcttctttta cgaaaaagct caatcacaat agatctggtt
    37441 tttgttttct aaaataagta actgtttctt cgttgttcgc ttttctgata gctttggcaa
    37501 ctcttctata ctaaaaaatc ccatgttgga agtttcatta ttctcaataa acttggcctc
    37561 ttcaccgtgg atcgcacaag caaaaacaag tttataatac tgaaaaagct gtggaatatc
    37621 tttttgttta ttcgtatcaa aaactgctcg caactgagta gtttctactg ttaatcctgt
    37681 ttcttcatag acttctttac gcacattttc ttcaggagac aatcctattt cagcaaatcc
    37741 accaggaagt gaccattctt tcgtccgttt atcttcgatt agtaggacct tgccatcttt
    37801 tttgatatag gcacgaacat ctacttttgg tgttggatgt ccttctccaa tcgttgtgag
    37861 cgcttttatt tcttcgaaag tttcttttcc tatttcactg atcagttcca atgaaatcgt
    37921 ccggatctcc tcaaaacgct ctttatcaaa tacatctttt ccataatata gaccagcttg
    37981 agaaagtgcg agtagtcttt tgtattgagc caacttcttg ttcattctct tcccttcttt
    38041 tttagcaaat gtatgactat gtaatcaagt atagaagact ggtttaatta cggcaaataa
    38101 atataatgaa atctgcaata aataaaagaa tgttaaaaaa ctcgagaaca aaagacattc
    38161 gacttctctg gggctgtgaa taaatggcgt tcaaaagctt gcatctgcgg taataagccc
    38221 caccaaacga aaaatatgac gagctattct tgtctggctg ttcttattaa ttgaggcagg
    38281 acagcttttt cacaacctcc ccactaaacg gtgttctcct accaactcct cggtcacaag
    38341 tcacaatatt catcaaacat gagaagctgt ttttttgaaa ttgctccttg tgactcggag
    38401 ctgaacgaca ggctcacgac ctctcggtaa acagcgttca aaagccaatt tttcgatatt
    38461 aagccatttc tttgttactt attgtcattg atttcttttt ctaatttatc caatagtgga
    38521 gtgtaatcca cttgagtata gtctgttaca tcaaattcat atagtgttcc taactggaat
    38581 ttgtcatatt ttcggtcggc gatgatcttt ttgaatgctt ctttcgtaat atgattggtc
    38641 cctttcgttc gatcttccaa tacgtcacca tagtgataat gatccatgat atagctcaaa
    38701 tgacgatctg attcacgatc acgtttgtac cgacgttgcc ataacacttc aaagtctgct
    38761 gttaggcgaa tcgtgatcac ctgatatccg tatctatctg ctaattcttg gagtcgtgct
    38821 ttttgcttat cactaaaagg atactcggac acaatcactt tctttcctgc ttccatatac
    38881 aaatcaagtg ctttgtaata gaaaggataa actttcgtcc tttcttgttc cgcccgttct
    38941 tccaaattgt taaacccgat ggattctgca tagtattcct tgatttcatc gagcgtgatg
    39001 gcatacatat ctggaaatcg ttcccgtagt ttattcataa gatatgtttt tcctgtacca
    39061 ggactaccag ccagaagaat gaaatacttt ttcatctcat ttatttccta agttaattgg
    39121 actttccaag ttcataaaca gtccaatctt atgcttgaca atttctttta ctgcttcatt
    39181 tgctggaatc acattatggc gaagagactt gttgatttct gtttcactaa aggtttcttt
    39241 agctactttc gtccagttga ctaaaagctc cgttccaaca ttgaatttgc ggatcccgtt
    39301 attgatcaat tcaggataat cttcttcttt cacacctgtt cctccatgga taactagggg
    39361 gacatcaact actgcatcga tttctttcag caagggaatg tttacttctg tttttgattt
    39421 gaattgtcca tgattcgtac cgatagcaat agctaatgca tccacgcctg tagcttctac
    39481 aaatttcact gcgtcttccg gtcttgtata taccttgtca ttttcagcga catggattcc
    39541 ttcttctgta ccgccgattg ttccaagttc tccttctacg gaaacaccgt gcgcatgggc
    39601 atattctact actgcttttg tcttcaggat attttctttg aaaggcagat gggacccatc
    39661 atacatgaca gaagtatatc cgctgtcgat tgcttctttg atatcatcaa agtctcgggc
    39721 gtggtctaag tgcaagactg catcaaccat ttcttcttct gcaatagctg tcattacatt
    39781 gactaacaca tgcatgccga tatatttagc ggtatcgaca cttgtttgaa taatgatcgg
    39841 cgaacccatt tcttttgctg cgcctagcat agcaggaagc atttctaggt tatgcgtatt
    39901 aaaagctcca actgtaaaat tcaactcttc tgctgttttt gttacttctt tcaatgttgt
    39961 atacatcttt tattgccacc ttatcttttt atttgtttcc tttgatcgtt acttgttttg
    40021 caatttgtcg catctcatcc attttgccca tgtagtaatc gatcccttga tcatcaccag
    40081 cacgagcagc atctgcacgc ttctggttat agaggctcat cagtttttta tacccatctc
    40141 cgatcgtctg tttattttcc aaactctttt ctaaatattg gatggcttga tcgttcacat
    40201 acaattcaga aaatttaagt ccaacttgtt cataaagttt cgctaattta tgcttatctt
    40261 gggtagtgga aatctcttgt ttcaattgtg taatctctga ttgaatcttt tcggtcgctt
    40321 ctggcgatag ggctttttct tcttttgcca gaactttttt cggttctttt tcttttttct
    40381 taaaaaatcc aaacatcatt ttccctactt tcaattaaaa tgctttcaaa actgggctta
    40441 agatccaggc atataagagt gctgcggcta ctgtatctac atcggttgct gtagcattgt
    40501 tgaatcccat cgaattaaag atcgttacta gcaaagcggg caataatgta ataaagaaac
    40561 catgagcaat accgccaatg atcgctcctc ggcgtccgcc aactgcgttg ccaaatatcc
    40621 ctgctgtccc tccggcaaag aaattggtta gcataccagg taaaatcatc gctaagccga
    40681 acatgggcaa agtaaacatg gcaataatcg taccaatcgt tgtcgtaatg aaacctaaaa
    40741 tgacagcatt tgggctataa ggaaagaaaa ctggacaatc taaggcaggg atcgcatcag
    40801 gaactaattt catagctatc cctcgaaatg ccggcacgat ttcacctaac agtagacgta
    40861 caccagctag caatacatac acacccacta cgaattggat ggcttgtaaa aaggcaaaca
    40921 tgatatagtt ttgatctcct gataattcag aagcgaatgg ttcgcctgca aataaaacag
    40981 tgatgatata tagcgggacc atcacgacca tgacagacaa ataagtatct tgcagaaatt
    41041 cgaaatgtgt cggcaacttg atatcttcga tcgacttttt attttcgcct ttctcaccaa
    41101 aaagcttagc aacaccggct tcaaataagt acccgatcgt acaaaaatga cctaaagcaa
    41161 tatcatttga tccagtgatt ttacgaatga tcggttgcgc tactgccggc atagcaatgg
    41221 cgaaacaagc tccgataaaa ccaccgacca agatcaatac gatccctcgc agaccggcaa
    41281 aatagccaaa gactgtcgtc atcgttgcca tccataaaat tgcttgacca gttaaaaaaa
    41341 tgtacttcca ttttgtgaaa cgagccaaaa taatattgaa tacaaaaatg gctaagaacg
    41401 tcagtgcaat atctctacct aaacccaaat cattcattgc ttgaccattg atagattcaa
    41461 tagaagggat gatcccttgc atatgaaatc cttcagtaaa gattttcccg aaataagtta
    41521 aacttccaac gatgatgctc gaaccggcac tcaacacttg aaatcctagg agtgtcttta
    41581 acgtgccaga gatgacttgt cctgctgatt tcttctgcag tagtagaccc aacatagcaa
    41641 tcaatgcaat ggtgatcgat gcctgagtca aaatattttc gatgataaaa ttgataacgc
    41701 ccatgttttg atgtgcaccc caaaagttag actagaaatc taattaaaag gggtgctttt
    41761 tttgcggaaa tatacatttg tttttaagaa aaaagtagtt tcagactatt taaataacga
    41821 aggcggctac aaatatcttg cacataaata tcaaataaat cgtacactgg ttagacattg
    41881 ggtaaggatt tataactatc atggttggga aggcttggtt ggaggtggca aaagctacac
    41941 tacaaaattt aaacttgatg ttatagaata tatggaaaca aatggtcttt ctatccaaga
    42001 aactgctaaa aaatttaata tcggttcaaa tagaactcta agtaaatgga tagagcaata
    42061 tgaagaaggc ggtgcttctt cacttgagag ccaaaaaagg ggcagaaaaa ttagtatgaa
    42121 ttccaagcta aacattccta aaaaacttaa agatgagtct cttgaagaag aagttattcg
    42181 tttaagagca gagaacgcat atttaaaaaa gttagaaacc ttgattcaag aacaagattt
    42241 gagcaagaag aaatcaaggt taaaacaatc cttcagctca aaaaagaatt taaattgaat
    42301 ctattacttt caattgcaca attagcgaag tcaacttatt attactgggt aaaaaaatta
    42361 gataagccag ataaatatag caagataaag caagaaatta cagcgattgt aaaagaatca
    42421 agaaactctt atggttatcg tagagtcact ttagcgttaa agatgaaagg atatacaatc
    42481 aatcataaaa cagttagaaa attaatgtcc caaatgggac ttacctgtca aatccgaata
    42541 aagcgatata aatcttataa aggaacagta ggaaaaattg ccaagaatgt gttaaaacga
    42601 aatttttcag tagatacacc caataaaaaa tgggtgacag acgtcactga attcaagata
    42661 aaaggaagaa aaatctatct atctcctata cttgatttat ttaacggaga aataattagt
    42721 tatagtatat caactagtcc aacatataaa ctgattgaag aaatgcttca acaagcaatt
    42781 aaaaaaaagg gaactgaggg ttcactgatt ctacattcag atcaaggatg gcagtatcag
    42841 atgccacaat atcaaaaaaa attaaaagag aataacatta ttcaaagcat gtctagaaaa
    42901 ggaaattgct tagataattc tgtaatagaa aatttttttg gtgtgcttaa atcagagttt
    42961 ttttatcgag aaaaattccg atcaattgag atatttcaaa gtaaattaaa tgagtatatt
    43021 aggtggtata ataacaaaag gataaaacta aagttaaatg gactatctcc agtagaatat
    43081 cggaaacagt ccattaaata gttcaacttt tggggttcag ttcatggagg ggcaaggctt
    43141 tttttgagtg gtggaagtgg attagagcat ggcaatagca aaacagcata gcggcatcct
    43201 cctatgggcc gccacacctt ttgctgccag aaaagaacgg cggccttgat ttctcaaaac
    43261 cgccgccagc aaaatacaaa atgggcgtgg gaaaggtctg cccaacagcg gtttttttct
    43321 tttctgccgc tgggcagatt gaatactata atttgcaatg tattacaaaa gatgctttaa
    43381 ccactttcca gtaaaagatt gtccatgacc agcatagatt ttatcaaatc caaaatctga
    43441 tacaaaacca atactttcat tatgaaacgg caaaattaaa ataggtatcg gggtatggct
    43501 catcaatcaa cttatagtgc caccattcaa agcgataaga ctgaaatccg ctgctttcca
    43561 tgattttacg caagcatctt cgattttgtg cctctgcatc ccctatccct tttgctgtat
    43621 gatgcgaccg ttcgtccata aaatcgaagt tacttcccat tgaaacaagt tcccctgtat
    43681 ccaggtggta gagcgtaaga tcaattgcgc ttccacggct atggctggat tgtgaggcca
    43741 cataaccctt tgtaatcaac tcggctcgct ctatattggg gtaaaatttt tcttttgtga
    43801 gattgtcctc cggttgcgct gcccaacgca ggaagcagtc caccgcagtt cttggccgat
    43861 atccatccca taaaagcaag ccatagccaa gcgcagccgc atggatttgt gcctcgcgca
    43921 gagcaaacgc cacggccttt gtgccgatga tgcgattcac ctcataccca tccaccggtt
    43981 ttcctgtgaa gttatcccat gtggcgtact tggcatccca acggacgcca tgcaacattt
    44041 catctaaaaa caaaaaacca ttttccatac ttatcacctc tttaacgcca atgtaatcag
    44101 gctgtcaatc agtgcaggaa gcgtgattcc tgcggcggcc atcatacgtg ggtagcggct
    44161 gtacgatgta aaaccgggca gggtattgac ctcatttaga acgatgccgc catcctcctg
    44221 caaaaaaaga tcaacacggg caagccctct gcatccaagc acccgatata ctttctttgc
    44281 cgtttcctgc acccgatttc gttcctcgac cggaatgtct gcgggaactg taatcatcgc
    44341 attttctgag cctttttccg gctcgttttc ctgatggatg cggaagatac cgtggctcag
    44401 ccggatttga tccacttcgc cgacaatcaa atcatcctcg ttccccatga ccgcacaccc
    44461 gacctcacag cccgaaatcg cttgctcaat taagattttt ccatcatatt gtcctgccgc
    44521 ttctatcgca gcgttaagtt cttccgtacc gtttactttg gttacgccaa aggacgaacc
    44581 tgaccgtgcc ggcttcacaa agacagggta ggtaagcgca cccgcctccg gcttgtcacc
    44641 tttatcaatc atttgaaatt cgggaacggc gatgcccgca ttttttgtaa gaatgtaggc
    44701 cagtgatttg tccatgcaag ctgcggagct ttgaatatca cagcccacat aggggatacc
    44761 agacaataca aacagcccct gtatcgcacc atcctccccg catttgccat gcaaaaccgg
    44821 gaaagccaca tcaatacgcc gtgtttcgta ttcgctttct ttcatgacaa gcagcccatg
    44881 cgttttccta tccggggaga gtatggcggg gagactgtcg gcttcccatt ccgtacatgg
    44941 cttcttgcat agcttccata caccgttttt tgtaattccg atgtagtgcg gatcgaattt
    45001 ttccgtatca atgttcgcag caatttctat tgcggctttt accgacacat catgttcctc
    45061 cgagcaaccg ccgaagatga ttgcgacttt tattctattc atgctgtaaa ctcctttcaa
    45121 aattgagaca attcctgatt gttttttctg tagtatcctg cagcacacgc tcagtgtagt
    45181 acgccgtatg gggtgtgatg atcacattcg gcatccttaa aagctgcgac aaaaagggat
    45241 ggtcaagcac tttctgcgag caatcggtat aaacaaactg atcctcgccc tccaacacat
    45301 ccagtgccgc accacccagc tttccgcttt ccaacgcctc caccagcgcc ccggtatcga
    45361 caagcgctcc gcgcccggtg ttgattaaaa atgcgccttg cttcatctct ccaatttgct
    45421 tctgaccgat cagatggcgg gtatccgcac aaagcggcac atggagcgta acaatatcgc
    45481 tgttttttag aagctcatca agctggacat aatctgcatc catttttcgg ctgttatcat
    45541 aggccagcac atggcatcca aatccccgca gccttttgac gaccgcttgc ccgatatggc
    45601 cggttccaat aactcccaca gtcatatccc ccagttcttt cccccggata cgatccaatc
    45661 tgaaatcttg ttgcgccacg gcgtgcatgg tgggttttgc accccgtatg gccatcagca
    45721 tcagcatcaa agcataatcc gcaacgctgt ccggcgaata cgcaaccgtg ccaaccgaga
    45781 ttcccattct ctcggcggca gtcgtatcaa tgtgatcgca gccgatgctg cgggtagaaa
    45841 tgtattttac cccgaccttt ctcagcgcaa gaattgtcgc ctcggaaacc tcggacttat
    45901 ggcttacgct aacgcattga ttgccagcgg ccaattttgc gttgtctgcc gatatcgcat
    45961 cgctaatcag cgtagggata atatgaaaat ccggcgataa agcgcggaaa gcatttgcct
    46021 catcctgttc gcatccaaaa acagtaatgc ccacactttt tctcattggt tctcctcctg
    46081 aatatccaca ctttccggga ggggataaca gattttgcat ttgtttgtat aaagcagctt
    46141 gcaatctatt atttccccgg tacctaaggc aacttgcatc cgtttaacct gggcatattc
    46201 ataaatcccg ccactttcac ggacatactg gatactgcca tttgtaattt tgtataatgc
    46261 ttggggctct ttgtcggcga acacctgacc gatgattttc tcatcatcta aggtcaccca
    46321 tatttggtag gtgcagtcgg tatcgtttcg cacttttaaa tcaatccagc cctctgaaat
    46381 ggttgcatcc acccctttaa tctcgtcact gtttggctct ggaaactcct ttacttcgtg
    46441 acctctgcgc tggataattg tcaatggcgt atgcaggaac aaccagaaag aaaaggtttc
    46501 ccccggtctt atcaataagc cgtttaaggt ctttgctgcc agctttaagt tgaacacctt
    46561 gttttcctgg tatatcatgt caaatccggt attgtggttg tataatgcgc aatccgtttc
    46621 aaagagcaaa tgggaaagcg atttttcccc tatcgtctgc gcatagcgac agccgtcaaa
    46681 tctcattccc gcataaaagc acatttttct ctgcgcccgt ctcattggaa gcaggaacgg
    46741 gaaacgctgt gtcaatcttt ttctgtccat aacataacat ccttttctca tttttctggt
    46801 tttaaatatt cctcaaggca aaccccttgg ttgtacatct ctgtggcagc ttcgatgcca
    46861 acatatcggt aatgccacgg ctcgttgctc acaccggtta tctctgtctt gtctggtggg
    46921 tagcgacgaa taaaaccaaa acgatagctg ttttcatcca gccatctata aacctcgttg
    46981 cctgttgaat gaattccgtc cgcattgata tccacagcaa gaccaagctg atgctcgctc
    47041 gttcccggca cggccaccca agtttctgct tccgctttag cctgtgcaga ggtgtagcct
    47101 ttcgccttat attcggcaat tttttcatcc ataatttctt gctgtttttc tgttgttcgg
    47161 tatccggatg cgacaatcgg gtaaactcca tcagttcttg cggcatcaaa caaatcttga
    47221 agatagggag aaatccgaat atctatccgc tcaccatttg atagttgctc aagctccaca
    47281 tcgtactgtg cggggatggg gttctgcctg ttcactaaaa tcaggctcca ttcctgttca
    47341 tctccctgtt ctttggcggt ggcaagagcg ttttcctcca aattctccac tacgtcagtg
    47401 ctgctgcctg tatgagttgc agggatgggc ggtatctgtg ttgcctccaa tacggaagcc
    47461 agtctccacc ccaaaaacag cgtgcagact gtgaacgaaa taatgaacgc acatagaaaa
    47521 gcccgctttt ccacggattg tttcatatgc cgtttgtgat gatccgcatt ggaatgatag
    47581 ttgctttttt ccatttgatc gaatgcctcc tttgcaataa aactacgatt tgtggctggt
    47641 acgattgtta ttatggcaag cgcatctgta ctttccctgt agccagtctg tagttttcct
    47701 gtagcagcaa aaaaagaccg gcagggttat acctgtcggt caaaatcggc tctataattt
    47761 ctaggactga tagaaaatca ttctatcggt cccttttgag catgaaaaaa caaaacatac
    47821 agaagctccg ttagaattga atcaccacaa cacaatcaaa ggagcgttct gtatgcctga
    47881 tcttcatcat atcaaactac tacttggaat caaagataaa aacattttca tcacaaatgt
    47941 ggaatcgaag agcattaaga atatcaagag tcttgttgtt tctgcgacgt taagtaaaga
    48001 aattcgtcgc tgtcctttgt gtaaacagat gaatcatgaa ggcatgatcg ttaagaacgg
    48061 aaagaaaaaa tcgctcattc aacttaataa atgtgcgaac caactgactt atcttgcttt
    48121 agcgaaacaa cgctaccact gtcgtggctg ccacacctat tttacggcga atacctacat
    48181 tgtcgataga aactgcttta tcgctaaaca agtgcgctat aaaattttag aagagctaac
    48241 tgaaaaacaa gcaatgacga caattgctaa gcattgcggc gtttcttggt cgaccgtttc
    48301 tcggacactc gcttctctga tccccatgac aaaagtaaaa agaaattggt taccgcgttg
    48361 tttattaatg gatgaatttc gttcactgaa aaatcaagtc ggtccctact ccttttcttg
    48421 tatggatggc gatactggaa aattactgga tattcttcct tcacggaaga aaaaggctct
    48481 cgtttcttat tttatgcaat ttgaacgacg cgcacgattg aaggtaaagg tcatcgtgac
    48541 ggacatgaat gtttcttatg cctctctgat aaaggaatgt tttccaaagg caaaactcgt
    48601 tgtggatcgt tttcacattg tcaaacatct cattcgtaaa tttgaggata ttcgcgtacg
    48661 aatcatgaaa agctttgatc gaaacgatcc aacacaagcc aaatattatc gacaattaaa
    48721 ggcgttgtct cggcttctga tcaaacgaca ggacaagctt gtttatgaca aatggaccaa
    48781 atggcgcaat tttggttggg cgtatctcac cgaaagtgaa gtggtggatc gtctgctttc
    48841 gatctctgac gaattacgaa tcgcctattt ttactatcaa gaaattcttc aagcgtttca
    48901 cgacaaagag gcggacactt tctttaaact tgtaagaacg atgcccaatt ccgttccaaa
    48961 agaactgcat tctataaaaa aagcttttat aaactatgaa tccggcattc gtttagccct
    49021 cgaattgcct tattcaaatg ccaaaataga aaatctgcat acccacatca aagcattgaa
    49081 acgagtcgct tatggctttc gaagctttcg gaaaatgaag accagaattt tcttactaaa
    49141 taatctgatt acctatgaat caaaaaacat ctaaagtaga aaaggaattc taccttagat
    49201 gttcttatct cactctatca gtcctatttg acaaagagcc caaaatcatt taagttttaa
    49261 atatttacaa tgttgatgtg agcggtaaat ccagccagaa caaaacgcca tccgaggtgt
    49321 tttccagcgc atactggagg ctcatggcat ccagcgtttt ttgtacgatg gcaagtccta
    49381 aaccgcttcg cccacttttt ctgcttcgcc cactttttct gcttcgcgcc tgatcaatgc
    49441 gatagaatgg ggtgaacagc cttggaagcg cagtatcatc aatgtgaacg cccatgttca
    49501 aaacaaaaag gcggcatttt tcagcaccag gctcactcca tatccgtacc tcgcctccct
    49561 gcggcgtgtt ctgaactgca ttcaatatga cattggatag tgccttttgg agcagcctcg
    49621 gatcggacag gacaatttgc ccggctggaa tatctgtgac gaaccgctgg ttgtttgcct
    49681 ctgccaaggt ttgaaaatcg ggcagcaact cggcaaccgt gcgccctatg tccaacggtt
    49741 cagctatggg tacgattctc ccatcattca ggctgacaag ctccagtatt tcggaaatga
    49801 ttttgccctg cctatccatc attttgatgc attcgcgcag atacttagaa tgatctttgt
    49861 agtcaccgat attttcaagc attccctcca acagaacgct tgtagccgcg atgggcgttt
    49921 ttagctcatg agaagctgcc gcaaagaaat atcgctgtgt ttcctccaac tcatgttccc
    49981 ttgcgatttc atcctccagc cttgcgatgg tttctttcag cctgacatac atggaatgca
    50041 tatcatgagc cagtgcgcca agctcatcct ttcgctccag cggcggcggt acatctttca
    50101 ggtttgccat tttattcgca ctgtccgcta aggctttgat cggcgttgtc atttgccgcg
    50161 caaagatata cgcgcataaa aggctgaata caaccattat cgcaatcata acaattcccc
    50221 gaattgtcag cccttgataa agcaatccca cacctgcctt gctttgagca acaatcgaaa
    50281 tattatcatc tctatgtacc acataaagaa agttgggtct aaaactattt gatgtattgg
    50341 catttggtgt ggcatagagt acgcttccct ctttatcttc aatataaaac tcaaaggatt
    50401 ggttattgta gtgaaacagc cctgccacct cttgaatatc aagcctatcg ctattctgaa
    50461 tcagttccac caatggctga taggatttta ctgtttgctg taattccatc actctgaaat
    50521 aagacacaaa ttgctgtgca aacagtgttg ctgttacacc gacaagcagt agcaggacaa
    50581 tgatcgtata ggaaaaaacc ttaatgaaaa tcccttttct ttccattatt atgattcctc
    50641 caatcggtat cctacaccgc gaatggtttt gatgatattt tccggcagct tggcccgcaa
    50701 atttttgata tgagtgtgga ctgtgctgcc atcaccctca aagtcatatc cccatatacg
    50761 tgacaaaatg atttcatgcg ttaaggttct gcctttgttc tgcaccagca gcaaaaggat
    50821 ttcaaattct tttcgtgtca ggggcagctc tgtaccgtca caaagtaccg tgaaatcctc
    50881 cggcagaagt gtcagcctgc cgacacggat ttcctttgcc agcgcaccgc tgcgccgcag
    50941 cagggcttcc acccgcttta gtaaaatctg catcttgaat ggctttgtta catagtcgtc
    51001 tgcctctgca tcaaacgccc ggatttggtt ttcgtcatcc gacagggctg tcatcatcag
    51061 aatgggagta tcatttttcg cacgaaattc acgcaaaagt tcatgcccgt tcataccggg
    51121 cagcataata tcaagaataa ccagttgata agtgttttcg taaaacttgg tgtatgcctc
    51181 atttccatct gtgcaggcat ccacctgata tcctgcctca gccagaaacg cccttactgt
    51241 attacagata tgatcatcat cctcgacaag tagaattcgt atcgacataa aaatccctcc
    51301 attttaagaa gataacataa cagtctgtag tttccctgta gtttcaaagc gatttctttt
    51361 cggattttaa tcatccgtca ttgggatact cgcttctttt catggtgtat gtatctatat
    51421 tattggttta aacgaattaa atcaagataa taataattaa caccttctta atgtttggga
    51481 tgtttcgatt acagcggttg tcaaaacatc ccgataatac tggcaagcaa tggatcagaa
    51541 tatcctttac ggatattctg atccaccact tgcccgcctg cggcgttctc gttttgcttg
    51601 ttggggacac cccaagcctc agcaaaatgc gcggcctctt ttttgcgaat gcaccttgcg
    51661 gtatggcttt tcacacaggc agggcctgtg tgtactccct ccggtcgctc ttgccgcact
    51721 ccgcgcagca gattcagtcc taataccgtt caagacagta gaaaatcagc aagtctatat
    51781 tcctcatatc ttcatcatcc gtgtccttgc agttacagga aatgtaataa tcgccaaatg
    51841 taaatcccag aatattttcc tcaaaaagcc gtacctcccc ggtattaaaa tcaatcaccc
    51901 catactcaaa ggcgcattag accagcagtt atccaatgtc tggagacttc accataaaga
    51961 atccagatgc cggccttttc aattctacca tatacggctg atacagcagc agcttcctcg
    52021 tctttgtttc gggcattttc catttctgtc atgataaagt ttcgcttctt catacatcca
    52081 tgtgtaaatc ttttctttct gtttcagatg agaatacttt ttatcggtct ggagcagcct
    52141 gccatctatc atcttatagt ttttccgtga caaaatacca tgctttctct ctcttcaaaa
    52201 ccatatccaa aatgcgccgg tttcattata ctattcagta accgcctttc ctttctttgt
    52261 acgcctgtca atcggctttt ccgcagtttt gggaatgagc cagatcgtcg ccatctttac
    52321 agcgccgggg atgcgtcccg cagcacaata gtagtttatc catcgtgggg gcacacccca
    52381 tttctcgcct gcctctttca acgtcatgta gtccatagta cacctccaca gggtacatta
    52441 taattctttt gctcgaagaa taaaagaaac aaaatgtgaa atataaactt taagaaaggt
    52501 gcatatacca acattccacg ggcagagtat gaaatataca atgtaagtgg gaggtgcgat
    52561 atggcgaata ttgaagattg tcccggcttt gaaactttcg gcgcggatgt gaaagcggcc
    52621 cggcaagcaa agcgcgtttc gcgcaaagca atggcagaga aaataaatat tgactggcgc
    52681 tatcttgcca acatcgaaaa cgacgggcca ttcccagtct gccggttgtc atacagctta
    52741 ttaaagcctg cgggcttcct gtggaacgct actttaaccc ggagatcatg cgggaggaaa
    52801 gcgaactgcg gcaaagggtc agccacaagc tgaaactctg ccccgaagaa tacctgccga
    52861 tcatcgaggg cgcgattgac agcgccatac taattgaaaa gccgaagaag aatgaaacgg
    52921 aggatgtgta actggcatcc tctgttttac ttttagcggg agctgcacag cgtagcttct
    52981 atttttttgc acttttttct ttccagaggg ctattttgcg ggtagtttgg ggctttggaa
    53041 acgtcttgtt agtggagaaa cagtaacgta gcaagcatag ggagtgtagc cactcccgga
    53101 aaaacggcct gccccgtccc tgccgggccg cgtccgtttt gcttgttggg gaaatcccca
    53161 aacccctgaa tggaaaggac ggtgaagcat ggcaaacaga aagcgaaaaa tcgtgctgcg
    53221 cgtccctgtg acgccggagg aacgggctat gattgaacag aaaatggcgc tgctgcatac
    53281 gaagaacttt tcagcctacg cccggaagat gctcattgac ggctatatcg tcaacatgga
    53341 caccagcgac atccgggcgc agaccgccga gatacagaag atcggcgtca acgtcaatca
    53401 gattgcaaag aggctgaacg gtatggggcc ggtgtacgca caggacatcg aggatataaa
    53461 gggggcgctg gcgcagatat ggcagttaca aagatacatc ctatcaagtc aacgctgaaa
    53521 aaagcccttg actacatcga gaacccggac aaaactgacg gcaagctgct ggtggcctcc
    53581 tttgcctgct cttatgaaac agcggacatt gaatttgaaa tgctgctggc gcaggcatac
    53641 caaaagggca ataatctggg ccaccacctg atacaatcct ttgcccccgg cgaagccacg
    53701 ccggaacagg cccatgagat cgggaagcag cttgccgagg aagtgctgca agggaaatat
    53761 ccctatgtgc tgactaccca tattgataag ggccacgtcc acaatcacat tattttctgt
    53821 gccgtggata tggtaaatca gcgcaagtac atttccaaca aacagagcta tgcctatatc
    53881 cggcgcacca gcgacaggct gtgcaaggaa aacggattgt ccgtggtgaa gcccggccag
    53941 agtaagggca agagctatgc cgagtgggac gcccagcgga aagggacgag ctggaaagcg
    54001 aagctcaaag cagccattga cgccgctatc ccgcaggcaa aagattttga tgatttcctg
    54061 cggctcatgc aggcgcaggg ctatgagatc aagccgggaa agtttatttc tttccgcgct
    54121 cccggacagg aacgctttac ccgctgcaag acattggggg aagcctacac cgaggaagcc
    54181 atcaaagagc gtatcaaagg ccgcgttatc accagagcgc ccaaagagcg caaggggatt
    54241 tctttgcgga ttgatctgga aaacaacatt aaggcccagc agtcggcagg ctatgagagg
    54301 tgggcgaagc tccacaattt gaagcaggcc gcaaagactt tgaatttcct gactgaacat
    54361 gggatagaca cctacccgga tttggaaagc aaagtggccg agatcaccgc cgccagcgac
    54421 gaggccgccg ctaccctcaa agctatggaa caccggcttg cggatatggc ggtgctgata
    54481 aagaatattt ctacctacaa gcagctctgg cccgtggcta tggaataccg caatgcagcg
    54541 gataaggcaa aattccggcg tgagcatgaa agcacgttga ttttgtatga agctgcggca
    54601 aaggccctaa agggacaggg tgtgaaaaag ctccccgatc tgtacgccct gaaagccgag
    54661 tacaagcgat tggccgagga aaaggaacgg ctgtatgaga agtacggcga agcgaaaaag
    54721 cagatgcagg aatacggcat catcaagcag aatgtggacg gcattttgcg tatgacgccg
    54781 ggaaaggaat ggacgcaaga gctatgagta ttccacgaat gaattaccct caatatcgca
    54841 aggcccggaa gctgacgcat gagtgctgca actattgtga cggcaactgc ctgttgctgg
    54901 acgacggcga agaatgtatt tgcgtacaga gcatttccta ttcgcttctg tgccgctggt
    54961 ttaaggccgc tgtcctcccg ctggatgcgg ccctgtatgc cgagatcacc aaagaccggg
    55021 acgaagtgaa acgctgctgt gagtgcgggg ccacgttcac gccgaagtct aaccgggcca
    55081 aatactgcgc ggcctgctcc aaacggatgc gccgccgcaa agaggccgag cgccagcgga
    55141 aaagatactg gaaacctacg cacttagagc tgtaaaagcc cttatatttc aaggcttttc
    55201 cggcatggtc agcggggtat gtgggtgttt tatcctatcc ccgccgaagt gctgttctaa
    55261 atgcgtagaa tttaccagca gaaaagcgcc gttttctctg gttccatgct tccgaatatg
    55321 gtatcataga aaaaatcagt ctgacggggg tatcaggatg gacggacaag aaaagctgct
    55381 ggactatgaa acgatcaaag ccgccgttgc cggtgagagg tgggccacgg aaaaagtgtt
    55441 ggcccattat gctgactaca tcaacgagct ttccacggtg gagatcagac aggcaaacgg
    55501 caaaaagaag aaagtcattg acgaagatat acggcagcgc atttccctga aactgctgga
    55561 agcattgccg agcttcccgc tggaacagag atagacggca agagggctgc accctcttac
    55621 gccgctttgc ggctatcacc tgcacacccc tgaaacagat acacccgctg cgcggctata
    55681 tctgtttcag gggtctaatt atagctgcaa cctacgcatt taagggattg aaaaccgccc
    55741 gctgcaaggc ttctcccgca tgtttgcagg ggcaagcgaa tacttcatcc tatccccgac
    55801 aataccgggt tctaaatgcg taggaatagg caaaaagaaa agacgccgga cgcaagcgac
    55861 cacatggccg ccgcgcccgg cgtctgctgt tcgttattcg tctgtgaagt ggaacttctg
    55921 gccgtcatag tcggcatccg tcatgcgttc cagcttggaa agggtctgct gggcctgcgc
    55981 ccgcatatcc ccatccataa ccggcatgac ggcggtgagc ctgtttatcg ttctgcgccg
    56041 gtctgcattg tggtacatac agatcaggtt ttcttcctcc acggtaaagt gcatcattcc
    56101 ttatacctcc aattcattct ttttggttct ggccgccgcc ttttttgggc tggcggcctg
    56161 tttgctgtcg gatagctgct tgcggataga gggccggggc ctgcgaatac tcacatcccg
    56221 gcgctcgtcc cggttaatca cggcatacac gccatgcctg cctttcatcc cggtaaaaca
    56281 cagggattta tagggcagca tggcaaagag ccggtcatta tccttggtgg aagcaatcgc
    56341 cgcaaagtgc ggggagatct ccaccatgaa atgcgtttta ttggggctgt taggcgcgga
    56401 cagatctttc aggctgtcca caatacgccg ggcctcggtt tcaatccggc tgtcatgcaa
    56461 agcggtgacg tggactttga aatcgccggg gacggcccgc ccccggctgt gctgctccgt
    56521 ccgtagcgcc tcctgcagca cagccgggtc atggggctgg gcctcatagt acaaaaagtt
    56581 tcccaatacc cggtcagggc ttccgtcaaa acgctggctc tccgggatgt cacgggtgcc
    56641 atgctcataa aagagccggt tcacactcac cggctgggcg gtttcaatga cgtgccggaa
    56701 atgctgcgga tagtccagct catagagatt gccccggata gtgccgccct gtgtgccggt
    56761 cagctccacc gcgtaggcca gtatcttgtc acgggtctgc tccccgtaaa atttccatgt
    56821 gttgtactgt cgggtgtctt tcaggaaaac atcacgttcc cggaaacagt acgtcccgga
    56881 gggccgggac atccagagca gggtcttgtc tgcggcctga tcgctggcgg catcccgcct
    56941 gataatgtct ttgtcaatgc caaagtcact ttgataaaac gcggtgttct gccgcatgat
    57001 ctgttccagc gcggccagaa cgtccacatt ttcaaacttc tgcatttact ctacctccaa
    57061 tccctttgat ttttcccgcg ccggtggctg cttggcctgt tcggtcttgg ccgcgttgag
    57121 ctgcgcccgg atagagggct tttctttctc cctgcgggcc gcaagctgta aggcgctggg
    57181 cttttcgccg gaaaggggct ggatgcactt gatacggtca gcgacgcgga ttgtggtgtc
    57241 gtttaactgc cgctgccatg ccccggcctt gggcgaccag cggaaaccgt tgcttttcag
    57301 ctcgtcgcgt acagcagcat ccggcttccc ctcaaagaag atttgcaggc ggttggccac
    57361 ccggttgatc tccacagtgc cgccgtcaaa ctcccatccc acataggccg cctccttttg
    57421 gcgggtcaat tcctcaatgc ggccctttaa ccggcgtatc tcggcgttat tgttggagag
    57481 ctgccaggac tggaacggtt ttttctcata gtgccagccc gacgccatat ccgctttcag
    57541 gttttcaatg cctctttcga tcagatgggg gcatccgtcc agcgtcccat gcttgcggta
    57601 gtaggcattg acggccttca tcaactcctg cgacgcttcc agcttttcca gtttcttttc
    57661 cagcttggaa acggcctgcg gatcgtcggc gctgatacca cccatgccgg tgctgcggat
    57721 tttgtcaagc aagccctgaa tgtactgaaa ttcctccatg ttgcggtcac tggcggcgtt
    57781 ctgcttttct ttcgcccgta ccgggaaatt ggacggcccg gcaatcagga cagaggggac
    57841 gcgggcggta atctcatagc ccttattcat gttctcggcc agcttgcggg cgtaggtgtc
    57901 aaggaggctg tctatctttt cgtgatactc tggctccaca cgctttttct ggcgctccgc
    57961 aatttccacg gcctgatcga catagtgccg gtattccgcc gtggcgctgc cgggccggta
    58021 gtcagaaaag ctcatggctt ccttggcgcg gcgggcggct ccctcattga tgggataata
    58081 gcggacagcc gtttgcgggg gcgcagcctc cgggggttcc tcctgtgtct ggccggaagc
    58141 aactgccaca tcctcaaaag atagctgttc gggttcctcc ggctgcggtt cgggcggcgt
    58201 attgttgata atgccgtcaa tcatgttttc gttctgctcc gtagacagtt cggcggtacg
    58261 caggggattt tcccgcaaaa actccggcac ttccatatag ccgaagctgt ctacatagtg
    58321 ggcggtgtcc tgtccattct ggtgcagcac caccacgtcg gaaacggaaa ggctgtgtcc
    58381 cctaaaatct gccgggtggt cgatgttgaa tgtgcggtaa atatcctcca aagacgtgct
    58441 tttatccagc ggtgccgtat aaacaaggtc atagttggca ctgtccacgg ccagccctgc
    58501 ggcctgtaaa cgctcgtatg gctcaaaccg atagtcgcgg gtttcctccc cgcctcgaag
    58561 ctggtagatg gaaaaggtgt cctgttgggg tgcttcatag ccagccgccg cgtattcctc
    58621 cacggtcata ccggctgcgg cggcctcctg cgcgatctcg gcctgtacct gtgctttgta
    58681 gtcctgcaag ctctggtcga agtcagccag tttcggcggc tccggcaact gatactggcc
    58741 ctgattgagc atggggcggc actcctgcac ataagagaga agcgccccca aataggccgt
    58801 ttcctccggc gtcagggttt ccccggactg taagcggccc tgcgccgtct gttccatttg
    58861 ggcaaggctg caatgcagct tcatataggg gacaaactcg cctaacagca tatcccgatg
    58921 ggccttgtcc tgctcccagc cctctatgcc ggttgtagcg attacatgct ttttccagtt
    58981 ttcgtcctgc gcgtaaaatt ggtggtagct ctggatatgt tcgatcaggg aaccgtccct
    59041 atctccaaaa tcctgccgcc cctcgtagct gtccggctcg ccctgaaaga tacagtcaat
    59101 gcggaacgcg gttttgtcat agcctgcctc tgccggatat gctgcatcca gacgggcaaa
    59161 cagcgcgtcg gcctcatgca acggcatttg ctggccgtcc tttagctggg ggctttcgct
    59221 ccatagcaca gtcacaagcg gctcggctgc cggatcaagg gccggggcct gttcttcctc
    59281 ggcctgcgcc ggggccgctg cctccggggt aacgtcaacc gtgacggcct cctgttcctg
    59341 ccgggcctcg cgctcctgct gaagctgggc aaaatggccg tcgatctcgg ttatcaattc
    59401 gctggccgtg gcccggatgg tttcaaggga ggctttcagc tcggataact ccctgccgct
    59461 gctccaatcg gccacatagc caaaagaata gtccgacgtg tccagcccgt aatactggca
    59521 gacggtatag gccacgcttt cggcctgtac ctcgcgggtg ctgcggtctg gccgggccgc
    59581 ctgttcctcg gcgggggcct cccggtcaat ggcgtggagc ttggcatggg caatctcatg
    59641 gatggcggtc tttagggtct gcaattcgct catgccctcg ttgatggcaa tgcgctgttt
    59701 tgcgtagaag cagcggccct tggccccgtc tgaaatcggc tcaatgctta tgggataggg
    59761 tgatgtccgt tccagcgcgg caaagaaatc ctgatactgc tgcacgtcgc cggtaagttc
    59821 actgatatag ggcatgggaa aatccttgcc ctcggtctgg ctgatgtcaa agactgtcac
    59881 caccttaaag gccggaaccg tcacttcctg ttcttcggtc acgggcttgc cgtccgcgcc
    59941 gatcacgggc tgctgggtgg ccgggtcggt tttctccatc tgctgcttaa ccttgaacgg
    60001 ggccggggcc agtatcttaa tgcctttctc gccccgcttc acatggcggt caaattcatc
    60061 ctgccacctg ttatagcccg ccacaatcga accgccctgc atggcgatca gcagcgtatt
    60121 gttcagactg taatcgtgca tcttggacat agcggataag taagccatat agcggctact
    60181 ttcaaaaagc tcctgtacgc cggtttccag acggtcagta atcactttca tgcgttcttt
    60241 gctgttcatg ccgtccagca tgatcgggat aaccgggggc ggcgctttgt cggggctttc
    60301 ggatgcctcc ggctgctggg cctgcggttc ctcccggtca gcttccggct gggggtagtg
    60361 catcacccgg tattcctccg gcaccggctg gccctcatgg acgcgctgcc attcgtcgcc
    60421 gcttctcacc agatagccgt actgggtaaa aacgccttgt tcctgctggg caatgtggcg
    60481 tccaaactgc gccgtatcaa tcccggcttt ccattcctcc ggcatatcca ccatgccgga
    60541 acggttcagg tagtagtcgc ccaactgtcc atccccccta acgtcgggaa gatgcacata
    60601 gtaatccaca ttttcggtgt agtcgatgat ctggccgata ttctcaaagc cgccacgggg
    60661 attttgcagg gcggcgttca gctctgcgat ctcggcggcg tcaagctggc ccagccgggc
    60721 ggcaaggaaa ttcagctcgt ccacgtcggc ggccagcacc atgtcatagg gaatggcaag
    60781 gtgtctgtcc tccgggcagg aatacccgtt gataaaaaaa tcctgcggat tgtcggcagt
    60841 aatgccaaca tcccgcaggg cggcttgcag cgtttcggtt gtggtgggca aatccagcca
    60901 gacgccttgt ttgccctgtt ccaaaaactg ccggttatgg acttggatag aaaatacttc
    60961 gttcacgcgg tcactccttt ctctgttctg tttcaaaaaa tagggggttg gggacttccc
    61021 caacaagcaa aaatccccgg cccggcaggg acgcggccgg gggattttac cgggagtgta
    61081 gccacactcc ctatgcttgc tgtgttactg tcctttagct cctgtgttca atgcggtagt
    61141 tgacgtactt gcccccggta tcagccaaaa gcaccgtccc gtcgtaggtt ttgccggtct
    61201 ttacggaata gaggcccttt accttgactt tgccggtttt gagcagcgca gcggcgatct
    61261 tcggggtgaa cgctttcttg cgttcctcaa aaaatcggtc attcttccac atgacgaact
    61321 ggcaggcccg gtttccgcag tagtagtttt tcttgccctc atagacagcc tcaccacagc
    61381 ggggacacgt cccgatagga acacgctcgg cctgaaacaa tttctgcttt tcctcactga
    61441 tacaggaata ggtctgcacc agctcccgcg cctgcgtctc gatgccgtcc ataaattcgt
    61501 caggatcggc ctgccccttg gcgatctcgg tcagccggtt ttcccattcg gcagtaagct
    61561 ggggagaagt aagcgcctcc ggcagcacca cagccagatt gatgccgtcc ttggtgggaa
    61621 tgagctgctt gccttttctc tggacaaagc ccatctgcac cagcttttcc agaatggcgg
    61681 cgcgggtggc cggtgtgcct aatcccttgc gctcggcatc ctccggcata tcctcggccc
    61741 cggcccgttc catagcggac aaaagcgtat cttcggtgta gggcttgggc ggcgtggtga
    61801 aatgctcggt gacagaggcg gccacgtctg caaaggtctg gccctcgcaa agctccggca
    61861 gctcccgcac cgcctcggcg tcctcgtcgg cgtcggtctt taaggaagaa cggaaccggc
    61921 gttcaatctc tttccagccg ggggaaagga cggtcttgcc cttggcggta aactcctgcc
    61981 cggcacaggt aaatgtggcg gtgacggcct catagatatg cggcccggcc acggcacata
    62041 agagcttgca gcagatcagg gacagcagct ttttttcact ctcggccaga gtgccaaagc
    62101 cctgcttcac aaattcagcg gtggggataa tggcgtggtg gtcggacacc tttttgctgt
    62161 tcaggatgcg gtcaaactgc ggggaaaggt tcaggccctt ggcaaacggc accagctccc
    62221 acaggccgga cacaaggctt tccacggcgg gcagcatatc gtcggtaaga tattgactat
    62281 ccgttctcgg ataggtcagc agcttcttta gatacagtgc ctgggcatag tcaagggtct
    62341 gcttggcggt atagccgaaa agccggttag cctcccgctg caaggtggta aggtcataga
    62401 gcttgggcgg ctgttccgtc tttttctccc gcgtcacgga aacgcaaacg gcctgcgctt
    62461 ttgcacaagc cgccttgacg gtgtttgcct cggcagcgtc ggaaaagcgg ctgcttaccg
    62521 cgtccgcgcc gcccgccgtg atatggacga tgtgatattt ctctttcttg aaatcggtaa
    62581 tcttggcgtc cctgtccacc agcattttta aggtcggcgt ctggacgcgg cccacagtca
    62641 ggttcttgtg gtacaggacg gaaaaaagcc gggtggcgtt aatgccgatc agccagtcgg
    62701 ccttggcccg gcacagggcc gattgataca gcggatcata gtcgccgccc ggtttcaggt
    62761 gggcaaagcc gtccttaata gcactgtcct ccatagagga aatccaaagg cgctcaaagg
    62821 gcttttggca tcccgccatc tggtagacga aacggaaaat caattccccc tcgcgcccgg
    62881 cgtcggtggc gcacacaagg ccggtcacgt cggggcgctg catcagcgaa cagagaacgt
    62941 caaactgctg tttcttgtcg tcggggacga tgtactgcca tgtttccggg agaatgggca
    63001 aatcctcata gcgccatttt ttgaaacgct cgtcatagcg tccggcgtcg gcaaaggaca
    63061 ccagatgtcc gatgcaccag ctcaccagat agccgttccc ctccaaatag ccgtcgtgtt
    63121 tctccgtggc cccgatcacg cccgcaatgc tgcgggccac gctgggtttt tccgcgatta
    63181 caagtttata tgtcattcct cgtcctcctg ttcactcaca aaatcagctt ccgggtcaaa
    63241 ctcggtttcg ggttcctcgt cctccaaatc ctcgtcctcc ccaaaatcat actcgcccaa
    63301 atcgtcgctg ccggtggttt cagccttggg ctttttgaac ttgaaatagt aaagggccgc
    63361 accgccgccc gccagcgcca ccagcaggaa cacgatcagg ccgcccgcgc cgcccttggg
    63421 ttcttcctcc ggggcttcgg gttcctccgg ctggggttcc tgcggctccg ggccgctgca
    63481 ctcggtcagg ttggttttac ataccgggca attcgtgttc acagccccgg ccttgcattt
    63541 cgtggtacag gagcagacag cagcgggggt gacggtttcc ccgtcctcca tcagcgtcag
    63601 cagatcggct tcatccacct gatttaagaa atggacagtt tcttttccct cgtcgtcccg
    63661 gtcaataatc agataaaaca cattgccgtt tttggtttcc acggtgataa actgcttgcc
    63721 atttttcgcg gcgctgccga tgtcgtcaat cagtgacagg ttcccgtccg gggacagggc
    63781 ggcgctggcc ccgccgccat tgaacagttc cagcagagaa gcaatttcct ccgggtcaat
    63841 ggagagggaa aaaccgccct cgccggtagc cgctacttcc ttttcgctga cggtcatata
    63901 gtcggaatgg acatagccga tgcgctccgg caagagaatt ttaatccagt cgccgtctgt
    63961 gccgactacc tcaaccgtcg tcccattggg aagctgggtg aacgcggtct tgtcaagccc
    64021 cgcgccggtg cggacattca gcctgccgcc gttggtggtg acggtgccgg tctgttcagg
    64081 ttcttttttg tcggtgccgg tggtgatctg gatgccgtcg tccgtggcgg caatgctcac
    64141 cttggaaccg aacagcgcgg aaaacaggtc ggtgatgtcc ttgccggtca gagggccggt
    64201 atctttttcg gcctcggttt ctgtcccgtc cgtggcggtg ccggtttcgt ctgtttcagg
    64261 ctccaaaccg cccgtagcgg gttcggttgt agcctccggc agcggggccg gtgccgggtc
    64321 attgccgcct gcaagggcgg taacgggaaa ggccgtgacg cagagcatca cggccagaag
    64381 tgcggggaga atacgggaaa tccgtctggt cttattcttc atgggcattg tcctcctgtt
    64441 catggtaagg ggttgcggca ggggcggcct gcattgcgcc gctgcgtaag aacgcggcaa
    64501 attcctccgg cttcatgttc atgccgcgca caagctggat gatctgcaaa ttctcctgtt
    64561 cggttttctg cgtttccagc tcccgaagct gtttctgaaa ctccgcgatc ttagacttgg
    64621 ttttctggat gtccttttcg atgcggtcaa gtttggttgc cataattgaa agctcctttc
    64681 tggcgttaag gtaaacgccc gtaactgtaa aaatgggatt gccagtagtt tgaagtaagg
    64741 ttcgtgtagg aaatcgggtt cccgcaatgc agcatcacat tgttgcccac atacaggccg
    64801 acgtgggaca cgccgggggt gtcgtaggtt cccttgaaaa atacaaggtc gccgggcttg
    64861 gcctgcgaac tggaaacagg ggtgcagatg ttatataggc cctgcgcccc cagccgtccc
    64921 acgttccatc cactatgatt gattacccac gaaatgaagc cgctgcaatc aaagctggtg
    64981 ctgggagagc tgccgcccca cacataggga taaccgatat atttttccgc ctctttgagc
    65041 atggcggcaa aggtggcatc ctccaaagcc tccgggggta cgtcgtagta ggtcggcggc
    65101 gtcagggtgg aggcgttggg gtactggctg ccggaaaaca gatcaggccg gtttcctagc
    65161 gtggacatat acagggaata gaaacttagc gtttcctcgt ccatgatata gactggcaca
    65221 tgggacaggt cgaagttttc cagcgtgacg tagcagatgt aatagtcata cggcacttgg
    65281 taggtgtctg tatgggtgtt gccctccgcg tccgtccatg tatcggtttc ggtgcggtaa
    65341 cgggtttcta ccacgacgtt ttctgtcagg atatattgct tgtcaaagag catggacaaa
    65401 tcaccctgta cctccccgat ggtaaatatc ccgtcatgga gcgccgacag aatggaaatc
    65461 agcacatagg ggtcatggct gatctcgtca aggtcaaaat ggtattcgtc atagtcatgg
    65521 gtggcctcgt agttgtccag atagtcttgc agctcggctt ccagctccgc gtaggcgtcc
    65581 tcggcggcca acatatcgct atcctcggaa aagtaagagg acgccgtgat gccgcttccg
    65641 gcgctgccga acatggcggt gcaggactgt aagccgccga tgataagcag catcaaaagc
    65701 cccaacacaa ggacggccag cgcccctttc cagtggcggg ccacaaagga ggccgcccgt
    65761 tcactttctt tggctgcggc cttggccgct ttcgtggagg ccccggctgt cttggccgcg
    65821 ccctgtgccg ccgcgcctgc ggtctggccc gctgtccggg cggccttggc gtactggcgc
    65881 ttgatctgct gtttctgcca gaaccgggaa atggggttgc tggccgcctg tgcgatctcc
    65941 gggttatccc gcaaagattt ctggtagaaa tactccgcgt tggcagacaa tagcctgcgc
    66001 tcggcctttt ccgcgtccca gtagggtttc agcctgtggt gccggatggt gctgcggatg
    66061 gcttttccgg cctgccgctc ggcaagttcc tcccccttat ggccgccctc cacacccacg
    66121 ttttcatgct cgacttcatg gattttcccg tggccgaata gaaaaacctc ggaaacagga
    66181 cggcctgccg gattgggttt cagggaggga ggccccttgt cctgtttgtc aaagtgcagg
    66241 acggtctttg ctttgccgct tgcctcgtca aagacggttt ccttgaccgg gacgcgcttc
    66301 ttggggatgg cggcgcgggc cttatccagc ttatcggccc gtttgtccga ttttcggata
    66361 tagggctgta aatccgggtc ggcccgttct tcctccgaca gttggagccg ggcggatggc
    66421 cggtgcaggg cagcgtcccc ctcggcggcc acagccccgg cctgcttcgc ggctttcttg
    66481 gccttatggc cgtcatggat ggcgtcggcc cgttccagca gcttatcggc ggtgccgccc
    66541 ggccccggcg cggacaaatc ctgttcggcc tcccggctgg aaatgttctc cacctcgccg
    66601 gtggcctgat tttccagcgt cagcccgtcg cgggtcatgg cctgcgtcac tttcgccttg
    66661 gctttcagct ctttcatggt ggttcacctc ctttgtggcg tcgccgggtc atactcccgc
    66721 cacctcgttt aagcgggtcg tcataatctt gtaaagctgg gtgttgtgcg ggatggggtt
    66781 ggtaaagggc agcaccacgt tttcaaagat caaaaggccc tcgccgggtt cggaattgtc
    66841 gatgtacttc tgctgttcgg tggacaaatt caagcgttcc gcaaggattt ttctatcccc
    66901 ggacgcctga ttgagcagcg taatgaagtc gctgttttca aggatatttt caatttccgg
    66961 ggaggaaagc aggtctttga cgttctgggt ggcacctgtt ggaatgccgc cccatttcct
    67021 aaaccgcttc caaatctccg cagaataggc cgccgtctgt tcctctttca aaagcaaatg
    67081 gaactcgtcg gcaaaatacc atgtggcctt tccttggctt cggttggccg tgacgcgccc
    67141 ccatatctgg tcttggacaa tgagcatccc cagctttttg agctgcttgc ccagctcctt
    67201 aatgtcaaag gacacaagcc ggttgccgat gtccacgttg gtacggtggt taaatacgtt
    67261 cagggagccg gacacataca ggtcaagggc ctgcgccacc cggtcagcct ccgggacatg
    67321 ctgatctaac aacgctttgt ggaggtcgga caggatcggc atattctccg ggcgggggtc
    67381 tgccagatag ggccggtaga tcacgcgcac agcccggtct atcacggtct tttcaatggc
    67441 ttccagcccg ttcttgccgc ccatgacaag ctcacagaac gacagcacaa agtcggattt
    67501 cagggccagc gggttatcgt cctccgaata attcaggttg atgtccagcg ggttcacaaa
    67561 gtccttgctg gtaggcgaca gccggattac ctgtccgtgg agccgtttga caagggggta
    67621 atattcggcc tccgggtctg aaataaaaat atcgtcaggc gtcgttaaga acacactgac
    67681 gatctcggat ttacagctca tggatttgcc gctgccgggg gtgccgagct tcaaggcatt
    67741 ggggcaacgg gcctgcttcc tgtccagcat aatcatgttg cgggacttgg cgttgatgcc
    67801 gtaatacatg gccgcgccgc cctgaaaaag ctcctgcgtc acaaagggga cgaacacggc
    67861 cacgctggaa gtcgtaaggc tgcgctgtat cttgatctga ttgacgccca gcggcaggct
    67921 gcttgcaagg ccctgttcct gctggtagtc cagccggaca aggggacagt tatgcttttg
    67981 ggccacgcct gcggcttgga acacgtcgtt attcagcttt tgcttggtgt cggccacgtt
    68041 gaggacaagg aacgtcaact ggaacagccg ttcattgcgg gtctgcaact ttgtcagcag
    68101 cttcttggcg tcctcgccgt aggtggcaag gtcgctggga agaatgtcca tatcgtaacc
    68161 gctgcggacg gcctttttct gctccgcaat cttcatagcg tcaaggtcgg taattttgcg
    68221 cttgatggtc ttgatcgcct tggtctgttc aatggcctgc acatggagat tgactaaaac
    68281 accgctttcc gtattgagga agtcggccag catatcgtcc gacagctccg gggacaggat
    68341 ttgcaggaaa cttaccgcgc cgtatttgcc gcccatgccg aatgtctttg cattgccgaa
    68401 gcacagggag gacggggcaa taaaatcctt ggtggagagg ccggacgggg ccagccactt
    68461 ccagtcaaaa ttgaatatct cgccgtccgg gtggtacacg ccatgcagca ggttcagccg
    68521 ttcccagccg tccatcacat gggctacggc ccccatgctc ttgaaatagc ctaacaggtc
    68581 aaagccgatg cgcttcaatc tggctcgcgc cgctttcacg ctttcggcct cgatggtgaa
    68641 tgtcaggtat ttggtcttta ccatgccgtt gttgccgttt gcaagctgct tttgcagaat
    68701 gccggtgtac tcggcccgga tgtcgtcgaa gtcgtccccc tgcggcgcga tctcaaagct
    68761 cttggcgtac tgcaccgggt caactttccg attgaggaaa gaaaactgga tatgaatgga
    68821 ggcgtccaca tagttataca ggtcgcacag tttttcaaag atagccgtct gcgtgtccgg
    68881 ctgggcaagc tgatagctga tgtccgcaaa ctcaatgcac ttggaaaaga cgccgggcga
    68941 tacccggcac acgccgtccg ggtacatgac ctcgtagggg atgctctgct gcgccgtgtg
    69001 gggcctgccg tcgcccttat atttacggat taccgcgtca atttcttttc gctgggcgcg
    69061 ggtcagcttt gttttttcgg tttctcttgg gatttccttt ttggacaatg gcctttacct
    69121 cctgttccat ctggtattgc cgcacaaggg cggtgtaggt gttgtcggtc tgatagggac
    69181 gctcctttgg ctggatgaag cagcactgga tgatctgcat aatcaccact tcaaggggct
    69241 ggccgtgacg ctcgtacatg gcaagcaaaa agcccggcag catggcaaat accatgagca
    69301 gggccgccgc gctgttggta agatagtcac gggtgagaaa atataagggg acgccgatca
    69361 ccagcgcccc ggaaaaacag atcagttgcc gtttggtaag cccaaacaca accttgcttt
    69421 tcacatgggt taagtccttg gggacggtta cataagccat ttggcacctc ctttcacgtc
    69481 aggataaggt cacattccac ctcgttcccc cacacgtccc agccgggggt tttctgtctg
    69541 gcaaacagct ccacgcgggg caaatcgccc gccagctcta cgattttttc acgggtcaca
    69601 tccggctttt tgctgtgttg ttcaatcggg ctgataataa actgatggac agaggcagaa
    69661 cgacgcttcg gcttgccgtg tgttgccagc aggcagattt ccgcgtttcc ccttgtccag
    69721 cggcccagcc cgtaaaacca tgtaaggctt ttacggttct gtttcagcca tacaaaagcc
    69781 acggtcttga atgaaaagcc ccacgctttg attaaccgca gagcttccgg cagcatgggg
    69841 aatgtggccc acaaaaacag caggcagtct ttggacgcca gccgttccac cggcagggcg
    69901 cacagctcgt caatgctcat ggtggaatag tgattttccg ctgcgccctg tacgtttttg
    69961 cagtcatacc gccacggcgg gtcagcgtaa atgatgttgt acgttgaaat aaacaagttc
    70021 ctcctgtgta tgcttggatt ttgggatcaa tgcgccccga atacggcctt tgatatactg
    70081 ccggtcttga acaggcagaa gcacagcagc accgtatagc ccatacagcc ccagattgcg
    70141 ccggatatgt cggaagcgga accgatattc tgtatcagca ccgcgtagat acccaccaca
    70201 accatgatta aaaaggcttg gaagcccagc gccagcaggg atttcagata cccttggccc
    70261 atgccgcgcc attccgcgtt gcccattgtg gcaaggggga taggccccag cgacgtgaca
    70321 acatagattt ccaccatgcg gccataggtc acaaggaaaa tgcagatgga aaggatattc
    70381 atggtgaggc ccacaacaag ggtttggaac cacagcccca aaagagcgcc cacgctcata
    70441 gcctccaatt ggctttcaag gtctggtatc agggtgttaa aatcaatgga tgtctgcccg
    70501 ataatcacac cggcgctttg attgacgacg ctttgggtgg cgtcgaatac gcccatgacg
    70561 atgttccatg tgttcgttac gatcaggatt gcaaacgcgg atttgaatat ccagcggaag
    70621 aacatggagc tgtcaaagtc gtgcatattg ttcttttccg ttatcatctg gataagctca
    70681 tagcacatga caagggcgag tatggccccg gctatgggga cgatcacggt ttccgacagg
    70741 ctgtgcagca tattgaaaat accgctgttc catgcctgcg gggttcgtcc cacgtcggcg
    70801 gcgatttctc cgactttggc atttaccgta tcgaacagcc cggacaggtt gcccgtgata
    70861 ccgtccatga ggatgccttt tatccattct tcaatgattt cactaatcac gggtagcacc
    70921 tcctttcccg cgccctcccg gtctggccgg gaggacgcgg aggcgattag ttaagggttt
    70981 ggacagggac aaaggccagg atcagcccag cagcccggac agcaggggaa ccagagtgac
    71041 accgatcagg gccacgccgc cgccagcgac aagctgcttg acaccctgcg attttgcccc
    71101 cggattgtcc tgcccgtatc cctccaacag attgatgccg ccccatacgc acagagcgcc
    71161 gcccagtccg atcacgatag tctgcaaagt agtaactgcg gaattaaaaa atgccataaa
    71221 tttacctctt tctgccggtt tccggctcat aatgattttt tgattttgtt gttggaatga
    71281 aaaaagccgc tgtttattca gcggcggcgt cctcgtccga caggtcgatt tcatacaggt
    71341 cgaatacttc atcctgcgtt accacttgct gccgtttccg gcgcgtgata gtcaaaaatc
    71401 tgtccacgtc aaaggtattc ttcttgtcgg cgtcggcaag gtatttgtac cggggatgct
    71461 tggtaatatc gaatttctcc gataaaaacg ggcgcacacc ccgtagctgc aagatacact
    71521 tgccgccgtc catcacggca atttcgtctt gggacatcaa ctcctttcct aatttttgat
    71581 agttcaatcc gtgggacgtt tggcttcccc ggttctcgct ggtgttgaaa ctgtcaatcg
    71641 tttctttccc cagcgcatcg gaaatctcct tggcattttt gccgcgccca ctaaggaaaa
    71701 gcacactatc gcagttatcc gaaatgatct cggcggcgtc cttgtaaatc gcttttagct
    71761 gcgactggct ctgcaaaata atagaggccg atatttcacg gcttcgaatg gtggcaatga
    71821 gtttatcgaa attgggtatt tggccaatgt tggcaaattc atccaaaatc aggcgtacat
    71881 ggacaggcag ccgcccgccg tacacatcat cagcccggtc acaaagcagg ttgattagct
    71941 ggctttggag catagccaga atgaaattaa aggtcgtgtc cgtatcgctc ataatgagat
    72001 acagcaccgt cttttcgtcc ccgatggtgt ccagctccat ttcgtcgtcc tccatcagct
    72061 cgcgtacctc ccggatgtca aagggcgcaa gtctggcacc gcatgaaatc aggatggaag
    72121 aacgggtctt gcctgcggac agcaggaatt tcttgtactg gcgcaccgca aaatggtcgg
    72181 ggtctttctg ctccaaacgc tcaaacatga gatcgacggg gctttgaaac tccgggtcgt
    72241 cctcgcgggc ttcactggcg tttatcattt ccagcagcgt tgagaagttc atttcctccg
    72301 ctggggcctc gtaccagata tagccgatca gggccgaata aaacaaccgt tccgacttca
    72361 cccaaaaatc ctccgctgac ttttccccct cgcccttggt gttggaaatc agggtattta
    72421 ccagctttag cacgtccttt tccgaatgga tgtagacaaa ggggttgtac ttcatggact
    72481 tggaaaagtt aatggtattc aggattttaa tgcggtagcc cgcctgctgg aacatcctgc
    72541 cggtttccag aaccaaagtg cctttcggat ctgtcaccac aaacgaagtc ggatagtccg
    72601 tggtcggaaa gcattgcatc aggttgggtt tcacgaaaaa tctcgttttc cctgaaccgc
    72661 tgccaccgat caccagcacg tttttattcc gcgctgtctt ggggtctttg ggcctgccgg
    72721 tcatggtaag ccgttccgtt tgggtgagca ggatattatt ttcaaacttg gggtcgatgt
    72781 aaggcgctat gtctttggcc gtcccccagc gggcgctgcc atactccatg cctttgcggt
    72841 atttcttcac gttcttgctc ttgcagtaca ccaccagccg cacgatcacg gcaccggcga
    72901 taccgataca caggtcaaac aggtgcaggc ttggcagagg gttggcaaaa gccgccgcaa
    72961 aaccatccgc aaaatgcagg agcttccccg acaggtcagc accagcggcc agccggtacg
    73021 cctccccgca tttcgcaaac aggtacacaa aaatcagata cgggaggttc aggatcagca
    73081 atttctttac gtcaggcttc acagttccag ccccctttcc ttgattttct ccttggcccg
    73141 ctgcttggtc tgggccgccg ccttttgctt cacagcggac aaaaccttgc ggatagaggg
    73201 ccgctgctcc ttggaaagcg tcttggcggt aaactcccga aacgccagat caaggttatc
    73261 tgcatccttg gccttgaaaa tcacaacgta gtggggcggc tgggtggtct tatcttttcg
    73321 taaggtaaaa tccacgccgt atttcttggc gcatggcttg aacgctccaa tgttggcctc
    73381 ggtgatctca atgttggaga gatcagcccc atgcttttta agctgcttta ggctctgctg
    73441 gccgtggtgc agcgtgtttt tgcccttggc ccggtgttgc aggtactttt tcagcgccgc
    73501 ttgcagcact tgagccgtga gcttgcccgt tttcatggac agggcaatgg tcttttgagt
    73561 aacttcttcc tgcaatcgca tccctccttg tcagaaagtc aaaagcggcg tctaaggcgg
    73621 aaccaccaga cgccgcaggt agatataggt caaatccgca cccgcaggcc ggaaaggtcg
    73681 tcggcccgga tgccgacaag ataccagttt tcggccattt caatgcgggt gggcctccat
    73741 ttgccgccga tcatcacgtc gaaacactcc ccgcaatgca ggccgccgta atagtcggcc
    73801 agatcaaagc ggatgtcgta acggtctgtt cgctcgtcaa aaatcaatgc gccctgcttc
    73861 atagggtcgt cctccttttc tcgttacagg ctttcgccct cgccgcagga atagtccggc
    73921 aggccggatt taggctttcc ccaatcgggc tgtgccatgt cgtgcgcgac aagggccgtg
    73981 tagtagttgg aaatggtgct gggggcgttg aacagcatag cccgcaggta ttgtttgata
    74041 ttgcggactt tcgttgtgtt ctcccgcaga cagtcaagga caaagcggat atgttcgccg
    74101 gtcagcttca tgtacttgga tttcaccagc tcggcagggt agtcgtcccc ggcgacacgg
    74161 attgtctttc gggcggtgca gacggtttcc agcatcaggt ctacgatttc gtcaagctgt
    74221 tcacggtcaa tgctcctgtc ctgaatgaga taggcatact cgatgttctc caaaatgatt
    74281 tcccgataaa tccgtacagc ctcatccttt cctgtccttt tccgttccgg cggcgtagcc
    74341 gctgcctcgc cctccatagg ggcaggggtc ggggatggga taggaatgga atgggtactt
    74401 tgtccatctg taattatttt ttcttttttt gataagtcag ttctttgtac ttctttattt
    74461 aattgcgttg gattttccga cgccggatta tccgatgtcg gattttccaa caccgggtta
    74521 tccgatgttg gattttccaa taccgggttt tccaataccg gctgttcgta gatggtatag
    74581 accatatcgg ccattttgcc ttttgcgtca cggccctgct cacgccggat atatccagct
    74641 ttttcaagct cccataccgc tgtcctgatc gcgtcgatgc tttcccggtt gatataggac
    74701 agtcctttta gggtatagtc ccaatcctcc ggcaaggaca acatctgcga cagcaggccc
    74761 ttggccttta aggtcaggtt cttattccgc aggtggtgat ttgacatcac cgtatagcct
    74821 ttgttctttt ccacacggaa aactgccata gcgttgttcg ctcctttcac tgtgaatttg
    74881 accgctgcat agtcggtcag cttgcccggc tgatagggac actctgcaaa ctggcagaat
    74941 tgatatttcc aatccgggcg gtaaaatcgg caggtgccgc aatcctccgg cgcgtccgcc
    75001 ccgccgccgt cgtagtgatc gaaaccgggc ttttcctgca tcagccgttc aaacgcccgg
    75061 tcagggccgg aagtaaatag catggcgtcg cctcctttct ctatttgggc ataaaaaagc
    75121 ggcgtcctgt tctcccatga cgggaaagag gaacgccgcg tttacggtgt cgtattcaat
    75181 ttatgatgtg ccgtatttgg ggtggcgggt attagcagta tggttcagca tatatgcggc
    75241 tcaatccgaa agtagtaaat tggtagtaaa ttgagttctc atatcctgcg aaatgcccgt
    75301 atttccgggg ctttcagcga taacctaaaa ttttttctat aatatttttc tcattataca
    75361 ataatgaggt ctttggtttt ctctcaaaac ccatcttata tctgataaaa ttctttctaa
    75421 attagggtct gtaaaactaa atcctaaaaa gagaaaagtt tttgttaaca aatctccttt
    75481 taaagtttct ttaaataacg cgtacgaatc atcatatttt tcataatcat ctcttgttat
    75541 tactgtcgaa ctgacatcat ctatatcacc atgcatttta taaacaattg tatccacatt
    75601 tggattagtt gttgctaact gagtataatt tttcttaacc tgagggtttt tataagcttc
    75661 tcggattgat ttttctatta gatgatcata attagttgtc caataagttt caataggtaa
    75721 acttgctagt attcgatgat tttcagatat ttctaattct tcaccaaaat tatccataag
    75781 tatctgattc aaaattcctc ttgatccacc attttcattt ttataatatt gagccagagt
    75841 aactaagtct gtttcttttt tagaatccaa cccgatttct gttgcaggat cattaagtag
    75901 ttccggccaa cttacatatc cttgtgacat cgataatcct gcacctgcaa atattgctgc
    75961 atttcctttt tcaatagctt cagagaacct ctttattaaa actttcttat ccattctacc
    76021 cggttccttt cgattcagta aattgattag agattagtga aaatggtgtt tttatataaa
    76081 atatctaatg tattacttcc tttagtgcat tccacagcat ctaaagccca ttttttcaaa
    76141 tcagcttttc gtaaataagt taattcactt aaatttaaag aatattttat ttgcagattt
    76201 tcttgcgaag aatagtgctt tataatgctt ctaacatcct cggtgctcat ttgaggatta
    76261 ctttccaatc gtggattctt tttttccact attgaagctg tcgtcagttc gctatatagc
    76321 catggcgaat acgtaaattt ctgttcatta gtgatttcat tgctcaaact aattgaatta
    76381 ggtgtattaa gaaaaaacag acattctgta ctatcaatca tattatttaa agctgtagaa
    76441 agcatcatat gaacatgact agttgttaca tttcttttat cataatcata tgtttttgtt
    76501 tgttccttat agcaatattt ttggtctatt ttttttaata aatcagaact gtatccccaa
    76561 accgaagaat caataaatgc agtaagacca aaattttcaa atagccatga tgcaaaacgt
    76621 atagctaatt tttcatcagc atgagagtga gatataaaaa tatctgcttt tatagttgga
    76681 aaccaatctt taataatttc gtctgcatct agaattttgc tgtccttaga ataataatca
    76741 actaaatcat tttcactttc aaatagattt tctattctct tgttaataga tttttggttg
    76801 tgatctattt gatttactac atgtgtatat gattgcgagc ttgaggagaa tgcatttaag
    76861 tcagcatttg taaaatccaa ttcatatgcc ttatacaagg atatccctcc attcttgtat
    76921 tttgatccac aatttattag gcaacataac agtataccct atcgttacat atcccattca
    76981 ttattatacc agtatttctt cgtgacacat aagggtgtaa cataataatt tcaaacgaaa
    77041 tgactacaag tagtcattga agcaaatctt cataagacac ctgtagaata tctttgatgg
    77101 ctttcaattg atccaactta atgtgttggc ggccaccttc aatcttaacc aacgtttccc
    77161 tagttatagc aattttacga agctgtaggt ctctaatcag ctcggtttga ccaattcctt
    77221 tttctaatcg gactcgtcta atattgctac cgattacatt ttctttatca ataatttttt
    77281 cctctttcaa gaatagcaca ccttttggac taaaattagt cctttttctt attaatctta
    77341 aagattcggt atgctacaat gggactagta ttagtccata ttcaatttta aggaggaatt
    77401 tttttgaaga aatttgcaat cattctaact tgcgctttac tcatcggaac tataagcggg
    77461 tgtaccactt ctgacacaag ttctacaagt acggaaacta gtacaacaac ctcagaaaag
    77521 aattacccaa tacatttttt tccggttcca gatggatttg aagcttatta tcatgataaa
    77581 aaactagatg ttcctttatc agaaactgaa tctactgaaa agattttgcc aattgaaatt
    77641 gaaagaaatc aagacgatat aaaactaaaa gctgatcttc ccttactgaa cagcacacaa
    77701 attgatagac atgaaaatat taaagttaat attgaaaaag gagcgttagc acaactttat
    77761 actgaaaaag ttgaacaatt ttttgaggct ggtgccaata aagacttttc aaaaataagc
    77821 gattattcgg ataacttttt taatgagacc caagatgaaa tcacgaactc aacttttatg
    77881 gctgaagata tgtacaatat gaagttgaaa aaaataaagt cgtatgatta tccattaaat
    77941 ctaacattaa ataaagggat actctctttt gtattagcag gttacgttga ctatgaatat
    78001 acagcagatt atttggagac gccccttcaa cacgataata acgatattaa ttttagattt
    78061 atctacaatt caaaaagtaa aacatggtta gttgatcaat tgagcactat aaatacggga
    78121 tttcatgaat tacctaagcc tgacaatgaa actgctttgg tcattaaaac attctaaaaa
    78181 agaaacgttg aaggaataat tattctttca acgtttcttt tattgttttt cagtttacgg
    78241 tcttacctga gcgaataatc tgatttctaa atgattggaa aacttcttgt ggttgataat
    78301 aatctgtatc tatttcaaat gtttctgaga ataattcatt gaatttttct actgaaatga
    78361 tgattttacc attctcctct cgactgtttt ctattatttc tgcctctaat tcaaataaat
    78421 ctagtgacga actaaaatca taaatcctgt catattgaac aaaaaaatca agaaaaagtt
    78481 gctcaaactc ttccttattt atcactagtg tttcaagcgg aacaacttta ttttcatcag
    78541 ccattcttcc aatttcctca ctttcatttt caattgtcca ttgttgcgga cgtatcagat
    78601 tttctctatc atttttcagt gtatagatca cttgtaatac acaacaatgc tttgtaaact
    78661 tattttttta gttagtcgaa tctttttaaa tgtgcgtttc ataccatgcg cttgatatat
    78721 tttctcctat tttttaaatc gtttatcaca acttttatcg ttttttcttc tgaaaaaaat
    78781 cttgtttaca tcgttacata gtttccaaaa agatacatta ctagtagaaa caacaagatt
    78841 aattttactt cccactgaaa tgggaagtat attttaaata ttttttctcc ttcaacttac
    78901 actataaagt atcttaatca cacgatatgc tagccactaa attcatcata tttgattcct
    78961 tttttaagat aatgtagcat ctttttatcc aataacgcaa ttgtttttaa ggataaattt
    79021 cttaagatgg tacatttcaa aatggcattt gacatatgaa acaaaaaaga aagaaaagag
    79081 cataagggaa aactgatagc accttcctac aggaaggtgg ctaagttggc tgtgccaact
    79141 ggttttcttt caaaatcatt tcataatttt tgatatcata aaaaaatcca ttttggacct
    79201 attttcggtc ataatttagt acctactttt ggtcatagtt tcgtccgtag ttttggtcat
    79261 agtgactaag gcttttctgt tcacaaaatt ggtttaaatt tgctttcttt aacacttcat
    79321 ttatatcata gcaattataa tgtttacaca acatcattcc taattttaac ggttgttcct
    79381 ctttatattt tttaagttct acattttttt gcgtttaatt acttttctct tttctttata
    79441 ttccgctcca actttctctt
//
LOCUS       DAZAOD010000004        78710 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000004 DAZAOD010000000
VERSION     DAZAOD010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.004"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            56..1180
                     /locus_tag="ACHDPO_000277"
     CDS             56..1180
                     /locus_tag="ACHDPO_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFN3367943.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            1407..2324
                     /locus_tag="ACHDPO_000278"
     CDS             1407..2324
                     /locus_tag="ACHDPO_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3367944.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            2317..3150
                     /locus_tag="ACHDPO_000279"
     CDS             2317..3150
                     /locus_tag="ACHDPO_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3367945.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            3233..4351
                     /locus_tag="ACHDPO_000280"
     CDS             3233..4351
                     /locus_tag="ACHDPO_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFN3367946.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            4372..6243
                     /locus_tag="ACHDPO_000281"
     CDS             4372..6243
                     /locus_tag="ACHDPO_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFN3367947.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            6237..7460
                     /locus_tag="ACHDPO_000282"
     CDS             6237..7460
                     /locus_tag="ACHDPO_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFN3367948.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7546..9480)
                     /locus_tag="ACHDPO_000283"
     CDS             complement(7546..9480)
                     /locus_tag="ACHDPO_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFN3367949.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            9706..10362
                     /locus_tag="ACHDPO_000284"
     CDS             9706..10362
                     /locus_tag="ACHDPO_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFN3367950.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(10436..10789)
                     /locus_tag="ACHDPO_000285"
     CDS             complement(10436..10789)
                     /locus_tag="ACHDPO_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFN3367951.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            10981..11910
                     /locus_tag="ACHDPO_000286"
     CDS             10981..11910
                     /locus_tag="ACHDPO_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFN3367952.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            11921..12757
                     /locus_tag="ACHDPO_000287"
     CDS             11921..12757
                     /locus_tag="ACHDPO_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFN3367953.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            13005..13781
                     /locus_tag="ACHDPO_000288"
     CDS             13005..13781
                     /locus_tag="ACHDPO_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFN3367954.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            13957..14700
                     /locus_tag="ACHDPO_000289"
     CDS             13957..14700
                     /locus_tag="ACHDPO_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3367955.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            14693..16273
                     /locus_tag="ACHDPO_000290"
     CDS             14693..16273
                     /locus_tag="ACHDPO_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFN3367956.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(16524..17003)
                     /locus_tag="ACHDPO_000291"
     CDS             complement(16524..17003)
                     /locus_tag="ACHDPO_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFN3367957.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17019..17771)
                     /locus_tag="ACHDPO_000292"
     CDS             complement(17019..17771)
                     /locus_tag="ACHDPO_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFN3367958.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17888..17958
                     /locus_tag="ACHDPO_000293"
     tRNA            17888..17958
                     /locus_tag="ACHDPO_000293"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17920..17922,aa:Gly,seq:ccc)
     gene            18319..19044
                     /locus_tag="ACHDPO_000294"
     CDS             18319..19044
                     /locus_tag="ACHDPO_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFN3367959.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            19299..19565
                     /locus_tag="ACHDPO_000295"
     CDS             19299..19565
                     /locus_tag="ACHDPO_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFN3367960.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            19562..19993
                     /gene="ruvX"
                     /locus_tag="ACHDPO_000296"
     CDS             19562..19993
                     /gene="ruvX"
                     /locus_tag="ACHDPO_000296"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFN3367961.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            20018..20323
                     /locus_tag="ACHDPO_000297"
     CDS             20018..20323
                     /locus_tag="ACHDPO_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFN3367962.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(20404..21549)
                     /locus_tag="ACHDPO_000298"
     CDS             complement(20404..21549)
                     /locus_tag="ACHDPO_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3367963.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(21610..22257)
                     /locus_tag="ACHDPO_000299"
     CDS             complement(21610..22257)
                     /locus_tag="ACHDPO_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3367964.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            22451..22744
                     /locus_tag="ACHDPO_000300"
     CDS             22451..22744
                     /locus_tag="ACHDPO_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367965.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            22788..23099
                     /locus_tag="ACHDPO_000301"
     CDS             22788..23099
                     /locus_tag="ACHDPO_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367966.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            23096..23720
                     /locus_tag="ACHDPO_000302"
                     /pseudo
     CDS             23096..23720
                     /locus_tag="ACHDPO_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            23861..24019
                     /locus_tag="ACHDPO_000303"
     CDS             23861..24019
                     /locus_tag="ACHDPO_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367967.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            24020..24382
                     /locus_tag="ACHDPO_000304"
     CDS             24020..24382
                     /locus_tag="ACHDPO_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367968.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            24419..25267
                     /locus_tag="ACHDPO_000305"
     CDS             24419..25267
                     /locus_tag="ACHDPO_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFN3367969.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            25257..26732
                     /locus_tag="ACHDPO_000306"
     CDS             25257..26732
                     /locus_tag="ACHDPO_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFN3367970.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            26998..27405
                     /locus_tag="ACHDPO_000307"
     CDS             26998..27405
                     /locus_tag="ACHDPO_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HFN3367971.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            27408..27623
                     /locus_tag="ACHDPO_000308"
     CDS             27408..27623
                     /locus_tag="ACHDPO_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367972.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            27627..28007
                     /locus_tag="ACHDPO_000309"
     CDS             27627..28007
                     /locus_tag="ACHDPO_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFN3367973.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            28141..28296
                     /locus_tag="ACHDPO_000310"
     CDS             28141..28296
                     /locus_tag="ACHDPO_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HFN3367974.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            28365..28838
                     /locus_tag="ACHDPO_000311"
     CDS             28365..28838
                     /locus_tag="ACHDPO_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFN3367975.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            28835..30529
                     /locus_tag="ACHDPO_000312"
     CDS             28835..30529
                     /locus_tag="ACHDPO_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFN3367976.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            30495..30680
                     /locus_tag="ACHDPO_000313"
     CDS             30495..30680
                     /locus_tag="ACHDPO_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367977.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            30684..31859
                     /locus_tag="ACHDPO_000314"
     CDS             30684..31859
                     /locus_tag="ACHDPO_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFN3367978.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            31852..33375
                     /locus_tag="ACHDPO_000315"
     CDS             31852..33375
                     /locus_tag="ACHDPO_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFN3367979.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            33431..33715
                     /locus_tag="ACHDPO_000316"
     CDS             33431..33715
                     /locus_tag="ACHDPO_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFN3367980.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            33702..34037
                     /locus_tag="ACHDPO_000317"
     CDS             33702..34037
                     /locus_tag="ACHDPO_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFN3367981.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            34332..34958
                     /locus_tag="ACHDPO_000318"
     CDS             34332..34958
                     /locus_tag="ACHDPO_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367982.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            35700..36536
                     /locus_tag="ACHDPO_000319"
     CDS             35700..36536
                     /locus_tag="ACHDPO_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFN3367983.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            36600..37031
                     /locus_tag="ACHDPO_000320"
     CDS             36600..37031
                     /locus_tag="ACHDPO_000320"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3367984.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(37093..38415)
                     /locus_tag="ACHDPO_000321"
     CDS             complement(37093..38415)
                     /locus_tag="ACHDPO_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFN3367985.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(38569..40209)
                     /locus_tag="ACHDPO_000322"
     CDS             complement(38569..40209)
                     /locus_tag="ACHDPO_000322"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFN3367986.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            40542..41012
                     /locus_tag="ACHDPO_000323"
     CDS             40542..41012
                     /locus_tag="ACHDPO_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFN3367987.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            41234..42337
                     /locus_tag="ACHDPO_000324"
     CDS             41234..42337
                     /locus_tag="ACHDPO_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFN3367988.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            42621..43301
                     /locus_tag="ACHDPO_000325"
     CDS             42621..43301
                     /locus_tag="ACHDPO_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFN3367989.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            43391..44425
                     /locus_tag="ACHDPO_000326"
     CDS             43391..44425
                     /locus_tag="ACHDPO_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFN3367990.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            44439..44774
                     /locus_tag="ACHDPO_000327"
     CDS             44439..44774
                     /locus_tag="ACHDPO_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367991.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            44758..47238
                     /locus_tag="ACHDPO_000328"
     CDS             44758..47238
                     /locus_tag="ACHDPO_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3367992.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            47294..48853
                     /locus_tag="ACHDPO_000329"
     CDS             47294..48853
                     /locus_tag="ACHDPO_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3367993.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            48850..50214
                     /locus_tag="ACHDPO_000330"
     CDS             48850..50214
                     /locus_tag="ACHDPO_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFN3367994.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            50385..51455
                     /locus_tag="ACHDPO_000331"
     CDS             50385..51455
                     /locus_tag="ACHDPO_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3367995.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            51470..52138
                     /locus_tag="ACHDPO_000332"
     CDS             51470..52138
                     /locus_tag="ACHDPO_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3367996.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            52158..52736
                     /locus_tag="ACHDPO_000333"
     CDS             52158..52736
                     /locus_tag="ACHDPO_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3367997.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            53137..54048
                     /locus_tag="ACHDPO_000334"
     CDS             53137..54048
                     /locus_tag="ACHDPO_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFN3367998.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(54426..55343)
                     /gene="rnhC"
                     /locus_tag="ACHDPO_000335"
     CDS             complement(54426..55343)
                     /gene="rnhC"
                     /locus_tag="ACHDPO_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFN3367999.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            55545..55982
                     /gene="zapA"
                     /locus_tag="ACHDPO_000336"
     CDS             55545..55982
                     /gene="zapA"
                     /locus_tag="ACHDPO_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFN3368000.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            56040..56588
                     /locus_tag="ACHDPO_000337"
     CDS             56040..56588
                     /locus_tag="ACHDPO_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFN3368001.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            56703..59063
                     /locus_tag="ACHDPO_000338"
     CDS             56703..59063
                     /locus_tag="ACHDPO_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFN3368002.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            59150..59464
                     /gene="trxA"
                     /locus_tag="ACHDPO_000339"
     CDS             59150..59464
                     /gene="trxA"
                     /locus_tag="ACHDPO_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFN3368003.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            59646..61424
                     /gene="uvrC"
                     /locus_tag="ACHDPO_000340"
     CDS             59646..61424
                     /gene="uvrC"
                     /locus_tag="ACHDPO_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFN3368004.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            61569..62468
                     /locus_tag="ACHDPO_000341"
     CDS             61569..62468
                     /locus_tag="ACHDPO_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368005.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            62461..63723
                     /locus_tag="ACHDPO_000342"
     CDS             62461..63723
                     /locus_tag="ACHDPO_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368006.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            63884..65782
                     /locus_tag="ACHDPO_000343"
     CDS             63884..65782
                     /locus_tag="ACHDPO_000343"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFN3368007.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(66112..66831)
                     /locus_tag="ACHDPO_000344"
     CDS             complement(66112..66831)
                     /locus_tag="ACHDPO_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFN3368008.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    67021..67068
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            67168..67500
                     /locus_tag="ACHDPO_000345"
     CDS             67168..67500
                     /locus_tag="ACHDPO_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368009.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            67487..69490
                     /locus_tag="ACHDPO_000346"
     CDS             67487..69490
                     /locus_tag="ACHDPO_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFN3368010.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            69509..69979
                     /locus_tag="ACHDPO_000347"
     CDS             69509..69979
                     /locus_tag="ACHDPO_000347"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFN3368011.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            70000..70584
                     /locus_tag="ACHDPO_000348"
     CDS             70000..70584
                     /locus_tag="ACHDPO_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFN3368012.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            70599..71585
                     /locus_tag="ACHDPO_000349"
     CDS             70599..71585
                     /locus_tag="ACHDPO_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFN3368013.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            71575..71886
                     /locus_tag="ACHDPO_000350"
     CDS             71575..71886
                     /locus_tag="ACHDPO_000350"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFN3368014.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            71908..73689
                     /locus_tag="ACHDPO_000351"
     CDS             71908..73689
                     /locus_tag="ACHDPO_000351"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFN3368015.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            73682..75058
                     /locus_tag="ACHDPO_000352"
     CDS             73682..75058
                     /locus_tag="ACHDPO_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFN3368016.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            75065..75700
                     /locus_tag="ACHDPO_000353"
     CDS             75065..75700
                     /locus_tag="ACHDPO_000353"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFN3368017.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            75730..77085
                     /locus_tag="ACHDPO_000354"
     CDS             75730..77085
                     /locus_tag="ACHDPO_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFN3368018.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(77277..78671)
                     /locus_tag="ACHDPO_000355"
     CDS             complement(77277..78671)
                     /locus_tag="ACHDPO_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFN3368019.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
BASE COUNT        26046 a        13286 c        16316 g        23062 t
ORIGIN      
        1 tatacataag tgaaagcgtt ttatataaga acttgaaaag aaagaaggga tagacatgaa
       61 aaaaagatac aaattggtga tagctttgct aaacattacc ctattattca gcttaagtgc
      121 atgtggaaaa actaacgaag aagtaacagc aaacatcgca gatccaatga taaaaaaagc
      181 cactacatta gaagtatatg tcgcaaacgg caaactgaca aactatgttg aaaatgctgc
      241 aaaaatctat aaccgcaaaa ctggagcaaa tattgactta aaaattgtga atgtagcttc
      301 gggaacagca acagtacaaa tgatcacccc aaaattggta acacacgaag atatgccgga
      361 tattatctcc atggcagaca cttcagcagc aggtgtgctg gaaaaatttc aagatgcttt
      421 ttatagtgct gatgaatatg gattttatga caaatatggc gatcagtttt atgatcaaaa
      481 attgaatatt ttgcgtcaac aaacgagtaa tgaaacgatt attccttggg ctagtgattt
      541 taccccagca ctttgttatt atcaaccaaa aaaatttgct gaaataggtg tagattttga
      601 agaaatcagt tcttgggaag aatatatcca ggtggcaaaa gcattaaaag aaaaaactgg
      661 tagttttgga attgccttgc cagaatctgg ggaccaagaa ttgtttatca acatgctagc
      721 ccagcagaat caatctttgc ttgatgaaga aggaaatatc cgtctgaata ctaaagaagc
      781 gaaacatgct gcaaagttaa tcaaagaaat gatcgactca gatattgtac atttctacgg
      841 tgcacaagat gctgagaaag catttcaaga atctgcaatg tttgttgctg gcggctggta
      901 tgctacgaat atgtctttga attttcctga tgcatctgac aaatggcgca tggctccact
      961 gattcctttt tcaaaagaaa atccaggaaa aggtgcagta tcaggaggat caagttttta
     1021 tgtccctaaa gatgcaaaaa atccacaagt ggcacaacaa tttcttacat ttatgctgac
     1081 agatgaagaa tgcttagcca acgcactgga gctgggcgtg gctacatcta actcattggc
     1141 ctatcaaaca gaagcagctg agaaaaagtt tgactactaa ggaggacaaa aatactatga
     1201 actattgaat aaaatcaatg aaaatacatc aaatactgtt ttaccagcca cttattcaga
     1261 tgctacgtct tatttgacta ccgctgcata taactattgg caaacaggtg attttgaaaa
     1321 ttcatatcta aaagaagcag aaaattttgc tcataagtac ggcgtaaaat taactggtga
     1381 ttaaaaaata ttaggaggac ttaacgatga tgcaatcttc gttaccaagc aagacaataa
     1441 agaacagcaa gaaaaaagca acagatacgt ctcataaaaa aagtgcttat ggattggtca
     1501 caccttttgt tattttcttt attgtgacga ttttgattcc catcattatc tcgtttgctt
     1561 ttagttttat gaaaattggc tactcatttg aatttgttgg atttgacaat tatctagcta
     1621 tcttccgaga tccattgttt attaaatctt acacgaatgt tttgattatc atggcaggat
     1681 caattccaat aacgatgcta ttagctattt actttgctgt tttattgaat tcagcacagt
     1741 taaaaggaaa aggatttttt agaactgtct attatattcc aaccattaca tcaacggtgg
     1801 ctgtagcttc cgtattcatg acttttttca atccgactgg gttattcaat ggatttttga
     1861 atgcgctagg aattaacggt gtacagtggt taacaaatcc tttttggata cgaatatcaa
     1921 tgatcatcac gatgatttgg cttagtgtag gatataacac tattttattt ttagctggtc
     1981 ttcaagggat ttctaaagag atatacgaaa gtgctgaaat agatggagca tcgaaatttc
     2041 ggcaattctt tttattaacg atccccatgc taaagccaat cattttaatg gccacagttt
     2101 tagccactat caatggcttg ggtaatttca atatcccaaa tatattcttt gggacttcca
     2161 atggaccaga aaattcagct ttggtcgtag gagtcaattt atataaaaca agttttgaaa
     2221 tggttgattt tggaaaagcc tctgctattg cctggacgat ggtgtttgta tctgttatat
     2281 tatcggctat tcaatttaaa ttcggaggtg ataaaaatga ctaaacaaaa gatacaaagc
     2341 agaattttta cgtacgtcat tattgtgttt ggtgccttaa tatttttgat gccatattta
     2401 tatatgattg tagcttcaac gcaaagtaat caagaaattt taagtggcgg aatcaatttc
     2461 aagtttgggg atatgctatt aaaaaactgg caagccatca tggcgagata taattatccc
     2521 ttgattattt ggaattcgat tgttattgct gtaatcagta cagttttagc tacagccagt
     2581 tctacaatgg cgggttatgc attagcaaag tatcgtttta tggggaataa actgttgttc
     2641 aatacagtta tgctatctag gatggtgcct ttttttacca cattgattcc tttattttac
     2701 attatgagtc gtttaggatt atcgaatact tatgcaggtg tgatcatccc ttcgattgcc
     2761 agtacaactt cagtgtttat gatgcgacaa tatagcagtc aatttcctac agcactgatg
     2821 gaggctgcca gaatcgatgg tgccaatgag tgggtgattt ttacgaaaat cgctgtaccg
     2881 attttatcac ctacgattat tactagtggt ttacttatct ttatgggaag ttggaatcaa
     2941 tatctatttc cattagtcat gctttcagat aaagataaat atacggttcc cttaattatc
     3001 aaaaatatga cggtttctag tacaggtgag ccaattaatt atggcgcaat tatgctaatt
     3061 ttagcaactt cagtgatccc aatggtcttg atttatgtgt gggcgcagtc taaatttaag
     3121 gagaatgaca ttggagctgc aaataagtaa aaaaaataac gaatgttaac catctagttc
     3181 gttctaggag caactccaca ttcataaaaa ttaaaagaat ggcgggatat ccatgaatga
     3241 acagacgaag gaatggtcaa gaaaaatttt gaatgtagct tctgaaaaga tagatgcgga
     3301 attagacaga atggggaata aaattccata tatttcttac aacggaaaat atacagacgt
     3361 aataaaggac agaggaatcg actggtggac caatggtttt tggagtggta ttttatggca
     3421 gctctttcac aagacaaaac gagaaaagtt caaagaggca gcaatacaac aagaacaatt
     3481 attagaatct gccctgtacc atttttcaga cgttcatcat gatgtaggtt ttttattctt
     3541 accatcggct attgcacatt atcaacagtc tcaaaacaaa catagtcgac aactagggtt
     3601 acatgcagct acggtacttg ctggacgcta taatatttca gggaactatt tagtagcatg
     3661 gaatgaccat aaacctggtt ggatgattat tgatagtatg atgaatttac cattactgta
     3721 ttgggcttcg agggaaactg gtgatccgag gttctctaaa attgctcggc agcatgcaga
     3781 tacaacagct aagtatctag tgaggaaaga tggatcaacc gggcatatcg cagaatttga
     3841 tgcagaatca gggaaatata ttcggttact tggcgggcaa ggatacaatg agaattcttg
     3901 ttggagcaga ggaaatgcat gggctttata tggattcgcg ttaagttatc gttacacaaa
     3961 aaatccgtac tatctagcta tagcagaaaa gatagcagta aattttattc agaaaatcga
     4021 aaaaactggt tatattcctc tcattgattt tgctgtaaaa gattcgaata ttgataccag
     4081 tgctggagta tgcgctgcat gcggtcttct ggaattagca ggatatgttt cctctgtacg
     4141 atcaaaaatg tatcatgaag ctgctatcaa tatactccaa aagacagaaa agcactatgc
     4201 aaattggaat atggatgaag atgggatcat tggaggcgga gcagaagcat accatagaga
     4261 actgacttat aatgtgccac tgatctattc tgattatttt tttattgaag gcttacttcg
     4321 attagaacag tcggaattag ctatttggta gtaaaaagag gagaaaatac aatgaaacat
     4381 ccagtaccac tattaaggac cagacaggat tactttgact tatttaaaaa gataaatcaa
     4441 ccactccagc cgttttatcg agcaagtggc gcacaaattg attatataca tcaaggggta
     4501 ggatatggaa ataaaattgc aggaatggaa ggattctctc gggttttatg gggagcgggg
     4561 cccgcaattg accaattaga tgaacgatgg ttgaaattaa ttctatcagg aataaaagct
     4621 ggaacagatc cttcccatcc cgattattgg ggagaaatac atgaaagaga ccagcgtatg
     4681 gtagaaatgc ccgcaatgtt attagcgtta tatcatcatg aacaattatt atggaaaaaa
     4741 ttagatacag gagaaaaaag ccagattatt cattggttct cgcaaatttt tgaatatgaa
     4801 tgtgcagatg gtaattggca attttttaag ataattgtcg gaacaattat ccaaaaattt
     4861 ggttatccag ttaaagaatc agcactgaaa gaagcatttg ataatataga aaattgttat
     4921 cttcaaaatg gctggtatcg agacagttca agaggtcgcc aagattatta taatcctttt
     4981 gcatttcatt attatggttt gatttatagc gtactagaac cagaaaagcc cattagccag
     5041 atatataaga accgagctat tgatttttct agagactata ttcatttttt tgcggaagat
     5101 ggtgcaaatg tgccttttgg tcgaagcatg atttatcgtt ttgcagtttc aagcttttgg
     5161 tcagctatgt tgtgggccga tcttttgcct tttaaattag gtgaaatcaa ggggttagtc
     5221 aatcggaata taagatggtg gatgcaaaaa gaaatatttg atgaaaaagg tatcctgaat
     5281 attggttata cctaccctca attgacattg actgaaccct ataatagtac gttatctcca
     5341 ttatggctga ataagatttt tttattgttg gcgctacctg aagaccatga gtattggacg
     5401 gctaaagaaa tgcctatgcc tattcgtgaa ggaactaaac ttctttcaga agccaatttg
     5461 ctcatacaac atgataatgg acatacattt tttttgaatg cgggacaatt agggccaaat
     5521 ttccatacat tgaccaatga aaaatattta aaatttgctt attctagtca atttggtttt
     5581 tcgataccgc gagcgaatca attgaaagca gaaatggcaa tggattcaat gctagggatt
     5641 cagcgagcgg acacatatat cacgaccagt tttaagaatg agagcatcaa aacctatgga
     5701 cagttcatcg ttcgaaataa tgtacgagac attgtatgta agaaagaggt acttgcctct
     5761 acatgggaac ctactttaca ggcaaaaatc agaacttggc ttattccttt tgaaggctgg
     5821 cagattcgcg tacacaaagt agaattagat acagaatatg ttctatatga gacagggttt
     5881 gctattgaat gttctcctga gaaagaagga ataatcatag aagaagacaa ggaaaactat
     5941 agggtgagtg aagctggctt ttcaggtatt atctgtttaa gtgacgatac tattaaacga
     6001 aaatccacag ctattatggg tttgcccaat acaaacttga tgacatggga aaacactttt
     6061 attcctggat tagagggtac atttggaaaa ggaacccatt ggctcggaac aggagtggtt
     6121 gctcatcaag atcgggatta tagtttagaa gtatggaaca atcgtcccaa aattgatttt
     6181 gatgggacaa ccgggctaac tatccaaaat aaaaacaata aaaaaagact aaaattatgc
     6241 taaaggctgg tggggaaatg cttgataaag tgatgtttga agagataata catccagaaa
     6301 aatggataaa tgaatgttat aaagaattaa tggaaaaaga atggaataat gagatcgagc
     6361 gttgtcgcag acacacggag aggttaatca aacgtatcag taacagtcag tatcaattcc
     6421 caagcgagtg tcctataaaa ggacgttatc cattaagaga caatattggt tggacagaag
     6481 gattttggac aggaattaat tggttgttat ttgagaagac gggtgatcct ttatttcaac
     6541 aaacagctga aaaagcagat atagatttta tccacaggat tgactgtcaa attatcacta
     6601 atcatcacga tcttggtttt ttgtattctt tatcaaccgt agcagattat aaaataacgg
     6661 gaaatcgaaa aatgaaggaa gcttcaattg atgctgcaga aacattactt cagcgttttt
     6721 gggagaaggc aggagttata caagcttggg gagatcctag tgatccttca caacaaggta
     6781 gaatgatcat ggattgttgc atgaatcttc cattattgta ttgggcgagt gaagaaactg
     6841 gaaatcaaaa atataaaaaa gctgctcagg ctcatattca aaatgcagca gattatttag
     6901 taagagaaga tggttcaact tatcatacat tttatatgga tgtcaaagat ggaaaaccaa
     6961 gatatggaag tacgcatcaa ggttatagtg ataattcctg ttgggctaga ggccaagcat
     7021 gggggattta cggttttgca ttaagttatc gttatttgaa agaacaaaaa tattttgatt
     7081 taagcaaaat attagccaat tattttatga atcggttgcc agaagatacc atttgttatt
     7141 gggatttgat ctttgatgat tctagcagag aagaaaaaga tacatctagt atggtgatca
     7201 tggtttgtgg attattagaa ttaatagaat caggtctatt agacaaaaca gaaaagaact
     7261 tataccagtc tgctgtttgg aaaattatgc gacaattgaa agaaagatat gctacaacgg
     7321 aagaagaaga tggcttttta acacagtctg tttataataa gcccaaaaat aatggggtaa
     7381 atacaccttg tatttggggt gattactatt atttagaagc tttagtgaga atgactagta
     7441 attggtcttc ttattggtga aaaaggtaaa tatggaattt ttgtttgata aaataaaaaa
     7501 agaaaaacca aaacagcatg aatggtttct gttttggttt tttcgttaat tttcatattc
     7561 ttctaattcc aagcttagtt cttcccattc cgtcaatttt gtttcttgat cttgtctagc
     7621 agcttctaaa tcttggttca gctcattgag ttttacgtga tcttccaggt tttctggcgc
     7681 gaccatttct tgttccaact gatcgatcca ttcatcgatc cgcgccattt cttcttcaac
     7741 ctgagtaatt tttcgttgaa ggctacggat aagcttttgc tgttctttgc tttggtaata
     7801 atcagatttg ttcgtgggag caggagcaga ttctggctca tcttgtgcca acaattcggc
     7861 gatttcttct tcttcctgct ttttctctaa ataataatca tagtctccta gatagacttt
     7921 gctgccattt tcagagagtt cgacgacttt tgtcgcgatc cgattgatga aatatcggtc
     7981 atgggaaaca aaaagcagtg tgccgtcata atcgatcaat gcattttcta atacttcttt
     8041 gttgtcaata tctaaatggt ttgttggttc atccaaaatc aaaaaatttt ctttgttcat
     8101 cgctaacttg gctaaagcaa cccgtgcttt ttcaccgcca cttagcagag ggattggttt
     8161 ttctacatct tcgccagaaa ataagaaagc acctaaagca cttcggatct ctttttctgg
     8221 agtggtagga tgctcatccc acaattctgc taggatcgtc ttgtttgtat gcagatcagc
     8281 ttgaccttga tcgtaatagc cgatggtgac atttgtccct agcgtttctt ttccacggat
     8341 aaaagggatc tggtgaatga ttgatttcag caacgtcgat ttcccgatac cattcggacc
     8401 tactagagca atcgcttctt gacgacggat atctagattg attggttcag ataaggtgac
     8461 attatcatat ccgatagcgg catcttcgat ttgcaagact acatttccag aaggcttttc
     8521 tatactgaat agaaagtttg cttgtttttc atccccttga ggacgatcca gccggtccat
     8581 tttttctaat gtctttctgc ggctttgcgc tcgttttgtg gtagaggcgc gaacaaggtt
     8641 ccgagcaacg aagtcttcta atttatggat ttctgtttgc tgcttttcat aagccttcca
     8701 ttcacttgct aactgttctg ctttcaaatc tagatatttc gaatagttac ctttgtaatg
     8761 gcgcattttt cttctgctta attcatagac ttcattgact actttatcta aaaaataacg
     8821 gtcatgggaa acaatcaata atgcaccagt atagctttgc agataattct caagccagga
     8881 aagtgtctcg atatctaaat ggttcgttgg ttcatctaga atcaaaatgt cagggtgttg
     8941 caaaagcatg cgagctaaag ctaaacgtgt gcgctgtccg cctgataaag tatcgatttt
     9001 ctgatcataa aatgaagaat cgaatttaaa cccatgcaat acggaacgaa tttcattttc
     9061 ataaccatag ccgtttcgat ctgaaaaatc gtgttgcagc cggtcgtatt cttttaaata
     9121 agaactataa gcaggtgtgt ctggcgtacc ttcgctaatg aaaatctcta gctcgcgcat
     9181 ccgctcttcc atttgtctaa cttgttcaaa agctttcagc atctcgttcc aaactgtttc
     9241 attggaatca agtcctgtgt cctgagcgag gtatccgaga gtcgctgttt tatttttagc
     9301 gatctttcct tcatcaggtg cttcaattcc agcaatgatc tttaataaag tcgattttcc
     9361 agcgccattt ctgccaacta aagcgacacg agcgcctgta ctgatttcta aatgtatgtt
     9421 ttcaaataag acttctgcac caaaatggcg agcaatctga ttggcttgta ataatatcat
     9481 ggaatcctct tttctacttt gtgaattctc ctcaaataaa aaactatttt tcaattagta
     9541 gtctaccata aattccatta tactgcgaga tttgcagaaa tgataaataa atgaataaag
     9601 aataaaattt cacaatatct gagcaatgga attgattttt tcctataaat actgctatga
     9661 tggagaaatc aaagatgtaa ttagacaata cgtggaggtc atttcgtgaa agatcatatt
     9721 attccaaagg cgacagctaa aagactgcct ttgtattatc gctatttaag gattttaaat
     9781 aatgctggaa agaaaaaagt gtcttcaact gaattaagtg aagccgttca agtagatagt
     9841 gcaacgatcc gtcgagattt ttcttatttt ggcgaattag gaaaacgtgg gtatggttat
     9901 gatgtagaag atcttatgca cttttttgca aagacattaa acgacgatca attgacaaat
     9961 gttgcgctga tcggtgtagg gaacttggga agtgctttac taaaatacaa attccatcaa
    10021 agtaatagca tacgtatcag ttgtgctttt gatgtgaatg aggaaatcgt tgggcgcatc
    10081 gtagacggta tccccgttta tccaatggaa gatatgtcag aacaaatcaa gatccaacaa
    10141 atcgaagtag caattttaac gatacccgct gaaagagcac aagaagtagt caatcagtta
    10201 acggaagcag gaatcaaagg aatcttgaac tttaccgctg ctcgattgaa tgctccgtca
    10261 gatgtattga tccaaaatgt tgatttgacg aatgaattgc aaaccttgat ctatttcttg
    10321 cattctgacg caaatgcgca ttccgaaaat acagcagaat aaaaataaaa agcgattgaa
    10381 caaatgaagg caaaactttc acttgttcaa tcgctttttt ctgtttggac aacgattatt
    10441 ttgttcggaa gatttcttca taagaaaggg aatcatcttc tgctgtcagt tcatctagta
    10501 gataacggat ttttttaaag tcgatgaacc gtgcttgccg aaagacttct tttccttgat
    10561 gaaaaatcag gacaactggc gcagtcagca cttcaaattt actagctact tctggtgttt
    10621 caaatgcatc caaatgaagt gccggaatat cataatgtgt gagaagttcc tctagtcgtg
    10681 gacgaacagc gtgacaaaca ctgcaattag gcatcgaaag ataaatgacg gcaacggatg
    10741 actgttgcag tatgtcttga acttcagtca agttagtggt ttgtttcatt tttattctcc
    10801 cttttatgat agaagtgata tgtatgagac cttaatttaa tgggaataac agaaaaagtc
    10861 aattgaagtg ctttggtaaa aaataagagt tgtgtaaaaa tttacagagc aacttgtttt
    10921 ttttgaataa aagcgtatat ttgcaaagcg aatgaactag aaataaaaag gaggaaactc
    10981 atgttttctt ttattccaaa ttcggttttg cagatgagta cgattttctt atcgatcgtt
    11041 attgaagcat tacctttcgt attattaggc tgtcttatct caggcgcctt acaagtattt
    11101 ttgaccccag aacgtgtgaa gagatggctt cctgaaaatc gtatcttctc tatttttact
    11161 ggttcgatct taggattttt ctttccttca tgtgaatgcg gcatcgtacc gatcgttcat
    11221 caatttgtta aaaaaggcgt accagttcac acagcgtttg cttttatgct gactgctccg
    11281 atcatcaatc caatcgtgat tttttccact tttatcgcat ttggcaattc ttggcagatg
    11341 gcaagctggc gggtgatagg cagctttttt gttgcccttg tgattggtgt ctggcttgcc
    11401 tattttcaaa aagacgctgt attgaaagaa aaaatcacgt ctaaagtagc agaaaatcac
    11461 catcatcatg tccatgaaga agaacaaagt gagaagaatg aaccaaaaaa tcagctgatc
    11521 catcaaactg ggcatgtgtt gacacattca atcgacgaat tttttgatac aggtcgttat
    11581 ttgatcattg gcggattaat cgcagctgcg atgcagactt atttaccaac tagaattatg
    11641 ctaacgctcg gctcaacaaa gattttagcc attatcatca tgctgttatt ggcctttacg
    11701 atgtctcttt gctcagaagc agatgcgttt ataggatctt ctttgttaag tctgttcggc
    11761 acagcacctg tagctgcctt tttggtcttt ggcccaatgg tcgatatcaa aaatctactg
    11821 atgatgaaac gatattttac aggacgcttt attttatcgc tgatcggact gattgccctt
    11881 agcgttattg gattcacatt atttatttag gagggaaaat atgctgcggt ttttgatttt
    11941 atctgggtat ttcgaattga tgatgtactt gcaagtttct ggcaaactcg atcaatatat
    12001 caatgtccat tatcgctact tagctattct ttcaatgatt ttatctgctc ttttggcttt
    12061 agttcagctg tatttgtggg tcaaaaacgg aaaagcagaa gaaaaggcac acgagcacga
    12121 tcatgaccat gggttgtcaa aaccttatca acgtggaatc gcttatgtac tgctagcttt
    12181 gccagtaatc gtggggacgt tgtttccaac agttagtctc gacactacga tcgtagaagc
    12241 caaaggattt aatttcccag taagtaaaga atcagtaggg gatccggaga tgcagacaca
    12301 atacttaaag ccggatacca gtatttattt caacaaatca gactacttag accaaatgaa
    12361 tgagttgaaa gaaaagtatg gggataagca aactatcaag atcacagatg aaaactattt
    12421 agaagttatg gagctaattt ataattaccc tagcgaattc attggcaaaa aaatcagcta
    12481 tgaaggattt gtttaccaaa caccgaacga tagcaataca gatatcttct tgttccgatt
    12541 cggcattatc cattgtgtgg cagattcagg agtctttggt ttgttgacgc atatgccgga
    12601 aggagtaacg gttaaaaatg atgaatggta taaaatagaa ggaaccatcc aatcagacta
    12661 ttatcaacca ttcaagcgtg aaatcccatc tgtagttgtt acaaacgctg agaaagtctc
    12721 tgctccgaaa aatcagtatg tgtatcgttc tttttaaaag aacaaaataa ataaacatag
    12781 ctcagacagc tgacacgcaa ggacgtcggt tgtctggctt tttttgcatg atgtattcat
    12841 ttgtttgata tttattttag aagcagcatc ctgaaagtat ttgatatcgg tttcaaaggt
    12901 gttggaaaag attgtgaaga gaattacaat ttattcctaa catgtatgtt gaaaagttgt
    12961 atgaaatgat tttgatagta aaatatcgag tggaggtact ttttatggta acgcgtatat
    13021 ttattttgga tgatagtttg gtttttgaaa aaatgctagt agaaattttg gaagaatcca
    13081 gaattttatt aagtccttgg aaatttgaga tcgttcaggg attgaacgtt atacaatttg
    13141 ttgaattcat taaaaataat gaaatctatt cctcagatat ttttttccta gacatcgatt
    13201 tgaacgccta ttatagcggt atcgaactag gcgaaatgct tagagaaaag aatgaaaagt
    13261 gtaaaattgt ttatctaacg tctcatccga ataaagcaat aactgttatt aatcgaaaga
    13321 ttacgcctag tggttatttg ataaaagaat tcacttatga aaaaaataaa aaaagcatcc
    13381 aaagttactt attgaaagaa aaagaaaact atcctgttca acatgctacg aaaaaaaggt
    13441 ggacaactgt ccgttatggt aatagcgatc actatatcca ttacgatgaa atcctttatc
    13501 taatgagcat gccaggttat aaaaataaaa taggcctagt attgaaagat gaagagattc
    13561 tcgtaaacgg cacaattaaa aaatataaaa aatcactcga atatgagtat ttatgtaaag
    13621 atttaaaagc ttatatcatt aatactgaaa acattacatc tattagcaga gtaaacgaaa
    13681 tagtaacatt tgcaaatgga gaacaactag agatgggaaa gagaagtatt gataaactaa
    13741 agaattttat gcaagaaaag atagaaaatg aatcatttta aagaaaacaa agactcatat
    13801 cttacctgtt agaagagtgt tttcctgtag aagagaacaa cccaagtagc agcctagtcg
    13861 tttctatcct tttttgttat gcactctttt tgacatttac tccaccaata acgaagggta
    13921 caataaaaag taataacaaa caaaaggagt acagaaatga ttgaattcat caatgtaagt
    13981 aaaagttacg ggaaaaaaca agcattaaaa gacttgtctc tctcgataag acaaggggaa
    14041 atttttggat ttttaggaca taatggtgcc ggaaaatcaa ctacgattaa aagtttagtt
    14101 agtattattg aaccatcatc gggaacgatt ttagtagatg gaatgaaatt gacggaaaat
    14161 cgattgagta tcaaacaaaa aatcggttat gtgcctgatt ccccagatat ttttttacaa
    14221 ttgacggctg gagaatattg ggacttgatt tcagctgcct atgaattaga cacacaaaaa
    14281 aaagaaaagc gtttagcaga attgacagcg ctttttgata tgtatagtca tcaaaatgaa
    14341 acaatcgcaa gtttttcaca tggaatgcgt caaaaaacga ttttgatcgg cacgttgctg
    14401 ccagatccag atatttgggt attggatgaa cctttgcaag gacttgatcc tcaagcagca
    14461 tttgatttga aagaaatgat gaaggctcat gccgcaaaag gaaaaacagt cattttttct
    14521 acacatgtat tggataccgc acaacagtta tgcgataaac tggctatttt gaagaaaggt
    14581 gaattgattt atcagggggc agttagtgaa ttattgaatg gctcacctga tgaaacgcta
    14641 gaaaagattt atttgaaaat ggctggaagg caagcgacag gagatggacc gtatgtataa
    14701 gcgacaatta ttagaattaa ttcgagttaa tcttttatat gttaatccac agctcacgaa
    14761 taaagcaaga gagaaaggaa aaaagggaaa gcgattaact atctatcttt tgtctcaaaa
    14821 tcttttttca gggctgattt ttttactgat ttacggattt gctatgtttg ctatgaactt
    14881 tgttaaattg ccaggtttct ttacttatta cgtggcactt tttggtatgt taggtttaac
    14941 tcaaagtata tcagtcattt ataatatctt ttttgaagga aatgacctgc aagtattttt
    15001 gcctctgcct tttggacaag aacaggtttt ttcagcaaag attttggtag ttgctttgac
    15061 catcattcct tttgtttttc cgcttctagt catgtttatt ttaaccggat ggcgagctga
    15121 tctagggatt ttgcttacta tcattatctc aatccttttg ttttctctat ttttgattat
    15181 tcttttttgt ctggctagtt tgattgtttt tggtttggct cgaacagcag tgtttaaaaa
    15241 acatagaaaa acagtttcta gtatcttgct tggcagctcg atgctgatcg catttgctgg
    15301 aatcatgtgg atgaatcatc aaacggggac tattgaaaat gagttaacag atcggcatcc
    15361 gatttcgata ttattgccat tctatgatgc tgccagtcag ccactttctc aacaaggttt
    15421 attgggttgg ggaatactag ctatcacggc tctgggattt ttccttgctg taaaacagct
    15481 gatagtacca aagcttacag agcaactgac tgattcaaac agtgagttca aaataaaaag
    15541 aacccataaa aagaaccaaa atgtgcatca gcttttattt agttacaatg ctcaattagt
    15601 aaaagaacct aatttgatta tgcaagttct ttcttcttcc ttgttaactc caatcatttt
    15661 tattcttgct tttgccctag gaggcgaaat aaaattaact gatttagata ataagttaat
    15721 cggtgttgtt ttcctggtag ggatcgcatt ggctttctta acagttaatc agacttcttt
    15781 tatcagcaat cttatttctt tggatcaaga aaattttctg tttatccgtt ctttgccaat
    15841 ctctatgaac caatatttaa aagaaaagtt cagattcgga tggatattgc agagtttttt
    15901 aactggtggg atcgcattat taagcggact gtcttttcag ctgcctttgt tttttatccc
    15961 tagcttgcta tttggttctt tattcggctg ctacttattg tcactacgtt atttcgctag
    16021 agattatcgg ttgctgctgc tgaactggac caatattaac caattattta acagaggttc
    16081 aggaagtttg ggtttagtcg caactatgat gggttcattg atcatcagta ttattcttat
    16141 cgtcttatac ggaatgttgg ctttgtttta tccattttgg ttagtgaata ttcctgtgat
    16201 cggtttagtt ctaatacttt ccgctctatg gatcgtttat tatcaacgaa cgttttggaa
    16261 aaaatttgaa taaagaagag gggccgtgac aaaaatcatg tcgcagcccc ttttttacag
    16321 atagagggtg ttcaaaagtc agtttctcag tattaagtca attttatgta aaaatgtgag
    16381 aagctatttt tacaaaactt tttttaatac tcataattac ttcttattgc tcctgcggtt
    16441 acttgtcgca atgtttgtga gatattttgt catcgctcaa ggctgaacgt ctctttcaca
    16501 accttttctt tgttacactt cgtttattta aaaagccgtt tttttcgttt catcatgatt
    16561 gcgtcacgct ttactttgaa attacggatg ttatggttaa agacttctga taatacaaga
    16621 cctaaagcga ttgctccagc aatcataatt gcttggaccg cataatgagc cgcttctcga
    16681 taggattcag taacgagatt tcgaaccgct tgataagcta aaccaccagg gactagagga
    16741 accatcccgg gaatattgaa aatcgttacg ggcattttca aacgtttaga gaaaagatcg
    16801 ctgatgaatg ctactcctaa agaaccaagc aatgaaccaa aagcagcaga tccgcctatt
    16861 tgaacacaga tccagtagat catccagcca aaagcaccag aaagaccaca acaaatcaat
    16921 gaacgcctag gtacatttgt aataacggca aatgccgcag tcgctaaaaa actaaaagaa
    16981 aactgaataa atatcgtccc catacttgtg ttcctttcct aataaaaaag ctggaaaata
    17041 aaagcaatcg caaaaccgat catcgtagca gtcatcatcg cttctgttcc gcgagaaact
    17101 cctgagacat aatgtccagc tagcaaatca cggatagcgt tcgtaatttg aactccagga
    17161 actaaaggca tcacacatcc gataatgatt agatcctgat tgcttcctaa gccaaaacgt
    17221 acgctgtaga tagcggctat gccaatcaat aaagaagata aaaattccga taaaaatttg
    17281 attctaaaaa atttcaaact atatagataa gctgcgtatc ccaatcctcc aatgactaaa
    17341 gtcacaggta aatcggtcat ctttccgcca aataacacca taattgttcc actgatcact
    17401 gccgcgctaa cgatttgcaa ccagacagga aagaaagaac ggtctcggtc gattgcttgc
    17461 agttcgcagt aaagttcttc taatgttagc tctgaagcaa catatttacg tgaaagatca
    17521 tttactttta ctactttttc taaattaatc gaacggttgg taatttgttc cattcggatg
    17581 gtcgaggtac gatcaagacc aataaagaga ccggtttgag tgacatagct gaccaaacgg
    17641 aaatttccag aagctaaagc aattcgactc atcgtatctt ctacccgata catctccgca
    17701 ttgctttcca tcatgatttt cccagcgagt aaacaagtgt ccagcaacag atctaattct
    17761 tttcccgtca tagcatcttc tccaataatt gattgattag ttttatttta ctacaaaaca
    17821 taccagaagc gtaaagaata aaaaaacttg aggaaggaat aaaagaggcg tatactgttt
    17881 ttgtattgcg ggtgtagttt agtggtaaaa tcccagcttc ccaagctgat gtcgcgggtt
    17941 cgattcccgt cacccgctta aaataggttg tgaaaaagct gctctgcaac aagtaataag
    18001 aacagccaag caaaaacaac ttcttatgtt tttaacttgg atggacttat taccgcagat
    18061 gcaagctttt gcgcaccgtt taccaagcgg ttgtgaaatc agtgtattgt cttgagtatg
    18121 aagaaaattt ttgaataata ataaatacct tacagataga gtggtgactg attagagacg
    18181 aggaatccgt ctcttttttg tatttttaag ccatcttaaa acaggtttta ttttttgctg
    18241 tttctatttc tttctagtat ttatttatag gggaacatat gttaagattt agggagctgt
    18301 tagtaaagga gtaaagaaat gagcaaaaaa acaaccaagg cgatcgtggg gatcgtcgct
    18361 gctgtgattg caggggcatt cggtgtttcc accacacaaa aagattcaga tatctttcag
    18421 cagattacaa ctatttttga ttccacacca caagcttctc aagtagcgga tgtgccagaa
    18481 tatgatggaa aacatcaaga aatagaaatc aatgggaatc agccggaatt tacaaaagag
    18541 gatcttagcc tttccaaagg aacatgggaa agctattcaa atattgataa attgaacaga
    18601 gtaggacaag ccaatgctat gcttggaaaa gatttgttcc ctactgaaaa gagagagcct
    18661 ttgtatattg acccgacagg ttggaaacaa aagaaattaa gtgacgggca atggttatat
    18721 aatcgcagcc atttaattgg tttccagctg actggtcaaa ataacaacat taaaaacttg
    18781 atgacaggga cacgttcgtt gaatgctcca tacatgcttg ctcacgaaaa tgatattgcg
    18841 gcatatatca aagaaacaaa tcatcatgta cgctaccgtg tcactcctca ttttgagggg
    18901 aatgaactgg tagccagggg agtgcaattg gaagcagaaa gcattgaaga caaaaaaatt
    18961 gaattcaatg tctttatcta caatgttcaa gatggctaca cgatcaatta tgagacagga
    19021 caagcaacaa aaacaaaaaa ttagtagcag ctattcgaat tttttatgaa tattatgaaa
    19081 aaattgtgta aaaacataca ttcaaagaaa tatagcgtat actttatgaa aagagtactt
    19141 ttgataaagc tacagaaaaa aggaaaaaaa catacaaata gtgtttctta atttattcgg
    19201 aagtttggaa tatttgtttg tagttttccc tttcttcgag taaaataagg ttgtagaagg
    19261 taagctggaa ttaccttgcg ggaaagaggt gtagaatcat gggttttaca gatgaaaccg
    19321 tacgttttgg ttttgacgat agtcgcaaaa aagaagtgag cgaaacatta gcgattgttt
    19381 atcgggcttt ggaagaaaaa ggctacaatc caatcaatca gattgtcggc tacttgcttt
    19441 ctggagaccc gtcctacatt cctcgttatc gtgatgctcg aaatttgatt cgccgtcacg
    19501 aacgcgatga gatcatggaa gtaattgtca aggactacct ctcaaatcat ggagtgaatt
    19561 tatgagagta atgggcttgg atgtcggttc taagacagta ggtgttgcta tcagtgaccc
    19621 ctttggctgg acagctcaag gagtagagat cattcggatc aatgaagcag aagaagagtt
    19681 tggctttgat cggttgaagg aattagtagc acaatatgaa gtagaccggt ttgtagttgg
    19741 attacctaaa aatatgaaca attccatcgg accaagggca gaagcttcca tgtcatacgg
    19801 agaaaagatc aaagaactat tctccttgcc agttgattat caagatgaac gattaaccac
    19861 tgttcaggca gaacgtatgc tagtagagca ggcaaatact tcaagagcca aacgaaaaaa
    19921 agtcatcgat aaattagcag ctgtgatgat cttacaaaat tatttagacg gctcaggtaa
    19981 gcaattattt taataataaa agaaaagagg taatcttatg acagaacata accattccca
    20041 cgaccatgaa ggacacgaac acatcacatt ggtggatgac caaggaaatg aaacattata
    20101 tgaaatccta ctaacagttg acggacaaga agaatttgga cgtaactatg ttcttttata
    20161 tcctgctggt gtttcagaag atgaagatgt agaattacaa gcttatgcat acatcgaaaa
    20221 cgaagatgga acagaaggcg agttagaaca aatcgaaaca gacgcagaat gggacatgat
    20281 tgaagaagta ttcaatacat tcatggcgga agaagaagaa tagactataa agctaggaga
    20341 aaccttgata tgatagggtt tctccttttt ttatttttta ctgtatgcca tattgtatgc
    20401 catctagtca atatttaagt gttgtactaa tttttcaaca gtcttttctt tcgtttcttt
    20461 tgccaagtga ccgtaacaat cgatcgtctg actaattttt gtatgccgta atctagtttg
    20521 aacttctacc atagtagctc cagcgtccaa gagcattgaa gcatgagtgt gtcttgctac
    20581 atgcacaccg agaaatggaa ccatagcttt ttcacaaata gtaatcaatc ttgcataaat
    20641 agcgtggtgt gtgattagtt ctttatagat accacaaaaa atcatagtcg gatcagttac
    20701 accaagtgtc agcatatatt tccgctgatt aatctgccat ttttttaata tagaaattgt
    20761 tctttcatct agtggaagaa ccccagcact acaatcagtt ttaggatcac tgattttata
    20821 gccatttttg gattggctta gtgttttatt gatggtgacc gtattttctt gaaaatcaat
    20881 gtctgaccaa ttcaatgcaa gggcttcact gatcctaacc ccgctataaa agagaaagcg
    20941 tagtaacgtt ttatcaaagt cgtttcgata agtttcaggt ttgctgttta ggtaatcaaa
    21001 caaggtgatc agttgttctt tactgtaaac tttgaccttt tctttatgct tagtggtggt
    21061 tcttttaggc attaatacgt tgtctagtgg attagtctca ataatcccaa gattgatagc
    21121 gtagctaaaa atacgcttag aagttgaatg aagtaccttg tattggtcag tagtttcagc
    21181 ccagctattt acaatttgtt gggctttttt taccgtgact tcattcacac gaagatttcc
    21241 atattttgga agaatccact ttctaaactt gatttcagtt ttcatgaagg tggcttctcg
    21301 gacagtggtt ttatatgttt ctagccacaa gtcataaact tctttaaacg tttcgttgtt
    21361 cgctttttta ataccgtttt tatcgtagtc cacttgcaag cgtgacaagg caagctgggc
    21421 ttcttttttt gttttgtaac ctcgtctacg aaccttatca ggtttgccag tcattttgtt
    21481 cattccaaga taggcttcat agagccaaaa tttacctttt ttagtttcat attgcttgaa
    21541 tgttgccata atagttttcc ctccatagtg tagcaagccg tgggggcggt tggaggaggc
    21601 agtttattat tattttgaat agtgtttatt tagctcagta acaagagctg tgaactcttt
    21661 tagaagatca ttttcataaa attcttgata ctcttttttc tcatctgtat ttttttctga
    21721 atcattaatt aatgagtcat atcgtaaaag cgtatttaga agagctgcga gataagcaat
    21781 tggggtactc ccgtcaggaa attcaattcg agatcctgtt ttaagatatt ttattgcgtt
    21841 tgttaaataa atcttctgtg agacagtcag gttatcttct tcgatgttat tgatagcatt
    21901 agaaagatta gaatcaatta tagagttatt tttttcaata gtttttttca attgcttttc
    21961 aagcacattt cgcttaattt cgggcatcat atgcatatct cttaatgtat aagatccgtt
    22021 taatagatag gtagtggata catctaatac ctttgaaagt tgtttaagcc tggtgttatt
    22081 gggaagatta tagccatttt cccaattact aacggcacct ttactggccg gtggggataa
    22141 tttacctcca agttgttcca ttgagagtcc cttttcaatt ctagccagtc taattctttg
    22201 tcctgtctcc actgcttcgg ggtatttttt tctagccaca ttttcaccac cattcatata
    22261 ttttctctac tatatcacga tttaaatatg tgtgaaacat aaaagttcaa aaaagtatgt
    22321 taaaattctt gcaaatgaaa aggtatgatg gtatattgag tttataagag gtatagaaat
    22381 gtattcaaga gcctcttgca tttttttaaa atctttgtat agaaatgtat gctaacgagg
    22441 ggggataaat atggaattaa aaattgacaa actcacgctt gatgatccag cttttaaaat
    22501 tattgacgat cgagttgttc aacaagtaga gcaaactcaa ggaacgttac tttcattatt
    22561 agaaaaaaag taccagtttc caaaatatat gaacaaggca caagctgcta agtatatgaa
    22621 cgtttcatac aatactatga tgcagaaata tgttcctaac ggtttaaagt tgattatagt
    22681 tgatggagtc gtaagaattt cacaagatga atgtgatcgc tttatggaag aataccaaaa
    22741 ataaacgcaa gccgtggggg caaagggatt aataggagga aataataatg gaatcgacac
    22801 aaaataaagc aatcgaaaaa gtattatcaa caattcttac agaagacaca gcggcagaat
    22861 tagcaaactt ggaaggcaaa gcgctagaag aaacgtttga atgtttgtac gaacaaatgg
    22921 actatcaaaa attgctacca caagaaccaa cggtaagcgg agtattgcgt ggcttgaacg
    22981 atttagtaca agcagagttt aaagaacgac tttctattga agagtatcaa gaaattttgt
    23041 atcagcaagt tgagttgtta gcgagcttgc tagggcttga actggaggac gttgaatgaa
    23101 aactgaaatt tggaacggac acattataag atttgtcgat attaatgatg aatggtgggc
    23161 agtggcgaaa gatgttgcgg aagcgttagg tcttaaacag gttactagag ccattcactc
    23221 tttgcctaaa gatggggtta ctactagtaa ggtcatcgat tcattgggca gaacacaaga
    23281 tgtaaacatc atcaacgaaa aaaaatattt accgcatggc attcaaaagc cgtaaaaaag
    23341 aagccgaggc atttcaagac tggattttcg acatcatcaa agaactacgc cagtccacag
    23401 gacttgaagg ctttcaagta ttccgcatgc tagacaaaga acaccaaaaa gaagcaatga
    23461 ctaaattaag ccacgctatt actgaaccaa aaccagtaga ctacattaaa gcgaatgtga
    23521 tagccaataa agctgtatca actatttatg gtcattccaa aatggtaaaa aagaaagata
    23581 tgactcctga aatgttggtt gatcgtgaac ctattttaga tgagacagta gaattaatga
    23641 ctgttaaaga aaaatatggg ttgcagtttt cagtgagtga gaaaatttat aatcgttctg
    23701 ctgaattgca gacaacttag gagcattaac atgatcgaga acaaagaaaa agccttatcc
    23761 ataacagtct tggcggacag gataaaggca acttaattgg gataaaaccc gatattcttt
    23821 gttccgatta taccatatta aaaaatcgga gggaaccatt atgaaacgaa acttaattat
    23881 aggaagcatt ttaatcggcg gaattttcgg cttattacca ttaattgcaa aaatagctat
    23941 ctttgcagga ttagcgttat atctcttcac tgcttatgac gagtacgact atcaattaag
    24001 aactggaggg cataagtaga tgtacaaaac aaaactatta aaccaactcg atagccttga
    24061 attagaggaa attaatcaag ggatcgctga actagaaaat aatatcggga aaacctactt
    24121 tggaaattca ttcaatgaaa aactaacagt tttgtatgta ctcaaaaaac atgcagaaca
    24181 caaaataatt tgtcgagaaa tcaacgagct aaaaaatcag attttaaccg catggttaaa
    24241 cattactgat atgcaagaag caagggtgaa aacatttaat acatgggtaa agtatcagaa
    24301 tcaattaaaa ggtgctgaat ttgttcggga tgggttgaaa tacgaacttg agcagttgaa
    24361 gctcatggag gtgtctgaat gatttatacc agtattttga aaaaggagga gaggtttatt
    24421 ggcaaataat tatcaagcag caacggaatt acaaaagtcg ggatggtcaa tttatccctt
    24481 atctcctgga actaaaattc caataaaagg ctctagtggt tggaatgatg caactaacga
    24541 ttctaatcaa attaatgaat ggtggacgga agatgcaact agaaatattg ggttaatgct
    24601 tgaagatcat caaatggtgg tagttgacct agatcaacat tctgaaacac gaaacggcgt
    24661 tgagaattat aaaaaacttg cttcaatgta tgatccattt ccttctactt atacggaaat
    24721 cacaccaggt aaaggaatcc atttcttctt taaaattcct gatggtgtaa ttatccaaca
    24781 agaaacaggt gcatttgctg atatcttcgg gcgtgatgat aaaggtaaaa gtttaagcgg
    24841 gattgatatt atcactaaag gagttccaat agcgccaact atgattattt caagaagtgt
    24901 tgggagagca tatgaaccta ttgaaaacgt atctctaaat aatattgcac cagctcccga
    24961 ttggctagtg aacctactgc taaaaaaacc gcaagaaata aagactcaat accgacccgt
    25021 agcaaaaaca gggacagcaa aaaaattaga tatgattgtt caaggcgctg gcgaaggtag
    25081 tagaaacgat catttaacta agttatgcgg ttggttacta tggcacggtg tagataatca
    25141 aactttagca gaattgattt atacagcaaa tgcgtacaat gaaccaccgc taaaagataa
    25201 agaagtgaat caaattattc gatcgatgat taaaaaagat ttgaggggga aagctcatgg
    25261 ctcataagca taaattagat agtattttag actttcccga agccagcgag cgtgaagaca
    25321 atatcattga attgaaaacc tggatgtcac gattaagatg caataaagac gatcagatta
    25381 aaagtaacag tgttgtgaat gcagaattga ttttaaccaa tgatagcaat ttagctggaa
    25441 caattgctta taacgaattt agcggataca ttcacctatt aaaagattct ccttggatca
    25501 atcgtaccgc tggagaatgg gaagacagtt ttgaggatgc cttaacggca tatattgaag
    25561 aaaactacaa tgtagttttt gatgacaaca aaatacacaa agcagtagta aatgtggcta
    25621 gaaagaatgt tttcaaccca gtaaaagaac gtatcgaaaa agttaaatgg gatcaacagc
    25681 ctagactgga aacactgttt attgaccttt taggggtaga cgacaacctt tacacacgag
    25741 aagtaacaaa acgttggata gtcggatcag tcgcacgtat ctataaacca ggaataaagt
    25801 ttgagatcgt tccagttttg gatggaccgc aagggattgg taagagtacc gttccagcat
    25861 tactttacac ggatgatttt ttcaccgatt cattagattc gctaggtgaa aagaaagatg
    25921 attatatgca gcttcaaggc aatgtaatta ttgaacttgg agaattatct tcaatgaaca
    25981 aaactaaaat tgaacagata aaaaacttca tcagtgccaa gatcgataaa attagacctc
    26041 cttatggtcg gaatgtcata gcttgggcaa ggcaatgtgt atttattgga acgtcgaatg
    26101 atgggcagta tttgaaagat gatacaggaa accgccgttt ttatcctttg ccttgtaaga
    26161 ataagccaaa gatgaatccg tttaaaacaa aggatgaata ttttcttcaa gtgttagctg
    26221 aagcaaaggt gctttttgat aaaggacaac gaatctattt tagtcccgat gaagataaag
    26281 aagtcttaga aattgcaaaa gactatcaag aggatgccaa gatggagaat ccaattaaag
    26341 aagcaatcac taaatatttg gaaatggaaa tcccgtataa atgggaagaa gctccagcgt
    26401 gggcgagacg ttcttattat cagaactatc ctgacagtaa atgtaatgag aaaaatttac
    26461 agcatttcta taatggagct actatgcaac aagagtttta tttagttgat agcgtactca
    26521 ccgctgatat tttggaagct gtttttgata aacaagcaaa ggatttattg aatggtcgat
    26581 cagatgcaga aactaaaaag attgccttga ttattagcag tattcctggt tgggaacgga
    26641 agcaactgcc aaaaagaaat aaacgacgag gattttacaa taagtcaaat gcctatgaaa
    26701 ataaaaatcg agctggaaag tacaaaaagt aacgggtagt aacgggtcag taacacctag
    26761 cccgttacta gtttaccctt actgccccaa gggatacagc aatttggtaa cggggtaaca
    26821 ccttatttcc ttaaaacttt tgaaatagtt agctaatatg ctggggaata atgttactgg
    26881 attttacccg ttacctgtta ccaaaacgct agaacccttg tccccgttgg gattgagtgg
    26941 taacgggtac ctgttacgta ggtgttacca cgtgttacga atcaaggagg aaagtaaatg
    27001 ctcaatatta tttcaacaaa caaagcaccg aactttcaat atacagatga aatggatcgg
    27061 tttctaatga acacgctggc atttagtgtg ggattggtaa cagaagatta ttccacattt
    27121 gatccagaag tattaaagat aatggaagaa gaacctgatt ggctgcagga gtcagtagcg
    27181 tggtgtcaat cgctagtagt gggatcattg gtagatagtg gcaactatga tgatacaggt
    27241 gagctaatgg atgaatttaa ttgtctgctt aacctatatg atcgagcgag acaacgagag
    27301 cttacatcga atgaggataa tttgttttta aacatccatg ataagttctt ggctttgcta
    27361 ctaacagatg atgaattgat aactaattta ttggaggtag aataattatg catatggaaa
    27421 gtattagata cttcgatggt gagaaacaca ttgagtattc aaacactcaa gaagatgtag
    27481 actttattag ttttgaggaa gataaaatca ctaaagttaa ttttaaagac ggaacgtgct
    27541 tgaagatagt ttcgccttat attgaataca aatcaaaatg ggaacaagat gattctgacg
    27601 aacgagatcg ctttggttgg taatctatgg cagttaaaaa acaatgtaat catgctggat
    27661 gtaaaacatt gattgattat aggcagaagt attgtgggaa gcataaagca aagcaaacgg
    27721 caattaagcg tgaagaaaga aagcaaagcg aaggtaaata ttttcaattc tatcaaagta
    27781 gaacatggcg aaaggcttca tacttgtatc ggttaaatca tccagtatgt gaggattgcc
    27841 tagaagaagg cttgataagg aaagctgatg ttgtagatca caaaattgaa ctaaaagatg
    27901 attggaatag acggttagat gaaactaatt ttcgttcttt atgccatgca caccataatt
    27961 ccaagacagc caatgaaaga caaagacgag aaaagagtac cctttgagtt aagggggcat
    28021 agtgtgaaac ttactgacaa tcgatgccta ctcattttgg tacaaataac cgttgtgaaa
    28081 aggcataagg gtaattacaa ataacgatta cacttgtaat cacaagtgaa aaagtatata
    28141 atgaaagtag gagatttatt gaaaaataca attgttatta ctgataaaac agggaaacag
    28201 cgcaccattg agttacctca ttttggtcaa gtgaccattc aaatgcagaa cggaaaaatc
    28261 atttatatag ataaattaga taaagaaaaa ttctgatcga aaaacgaagg aatgtgagct
    28321 taattgctta cgttcctttt tcttttgtct gaaaggagga caacatggga caccctaaaa
    28381 tattacacga tacaaaaggc aatatatcaa gtgaagaaaa agcaatccgt gtggacgcta
    28441 gagaagaatt gttcaagcag caaccattaa taaatatcac gccccctgac tggatggcag
    28501 cgagcgctag aagtgaatgg aatcgtatcg taccaacatt aaaaaaagat tatccattga
    28561 gtgaagcaga ttatggttca ttggtagcct attgtttagc ctttgctcga atgaaaacag
    28621 ccgaagccga gataagaaaa tcaggtacgt ttatcacatg cgaaaacgga gtaaagaaag
    28681 ccaatccagc ggttcgggtt caatcacaag ctatgagtga tttgaaaaaa caagccacct
    28741 cactaggtat gaccttagaa tcacgatcaa aactagcttt gaacaaggtt aaaaatgatg
    28801 aacccgaaga cccgttcaaa gagttgatga attcatgaat gattacattg agaaagtcct
    28861 atcaggtaag ctgattgcac ccaagaaaat tatccaagcg tgtgagcgtc atataagcga
    28921 tttggagcgt tctaagtcag atagcttccc ttatgtgttc gatgaagaac aagccaccaa
    28981 agcgattaaa ttcattgagt tgctaccatc tacggacggt aaagcaatca agatgttagg
    29041 atttcaaaaa ttcattctag gcagtcttta tggctggcgt actaaagaag ggaattacag
    29101 gcgattcaat cgagcgttta ccagtatgag ccgtaagaat gggaaaacgt atatcgcaag
    29161 tggcatggct gccaatgcgt tgattatgga acaagaacca gcagaagcaa ggcaagtatt
    29221 gtttgtaagt aacgctttga aacaagctaa attgggctat gatatgctgt ctaattcact
    29281 tagaaacgtg gtcaagtcta gtaagttttt aagaccacaa ctgaaaatta tgaactctaa
    29341 gattcagcac ttgccctcta attcgttcgc tatggcactg gctagtgaaa ccagcacgct
    29401 agatgggttt gcaccaacaa ccgcaattct tgacgagtgg cacgaagcaa aaactcgtaa
    29461 aacgtacaac gtcattaagt caggaatgac ccaacaaaag aacggcttat tgtgtgttat
    29521 tagtaccgct gggcttgatt taaacgttcc tatgtacgag gaatacttat tgttagatcg
    29581 tgtgctaaaa ggcgaagaac aagccgacag gtactttata gcgatatggg aattggacga
    29641 tcccgaagaa attcacgatc aagagaaatg gatcaaagcc aatccgattt ttgaaagtga
    29701 agaaatcaaa aaagtaatga ttccaaccat tcaagatgat gtgaaccttg ctttgaaaca
    29761 aaataacctt aattctgtat tggtgaaaaa cttcaattta tggagacaag cgagtgagga
    29821 cagctatatg attgctgaag actggcaggc aaccgaagta gaaccacaag atattacagg
    29881 caagcccgtt tatatcggag tggatttatc taaaacagat gatttaacta gcgtttcatg
    29941 gatcgtaccg ctagataacg gcgaacttta ttgtgattca catagctttg tagccaccaa
    30001 atatgggctt caagacaaag aaaagcgcga cggtttgcct tatcgagaac tagaaaaagc
    30061 tggtgagtgt tccattactc aattagaaag tggaatcgtg gactatgacc aagtatttca
    30121 gtttattcaa gatttgattc aagaaaatga tttggaatgt atggggattt gttatgaccc
    30181 gtataacgct aattcgctta tcagtaaagc tgaaaaagcc aactacccaa tgttagaagt
    30241 aagacaagga acgattactc taaacgttcc gacccgaact tttagagaac aagtttatga
    30301 aggcaacgtt attcacaata aaaatacgat tctcacccat gcagtgaaca acgctatttt
    30361 aaaaacggat aacaacggca ttcagattaa taaatcaaag aacagtaaca aaattgatcc
    30421 aatagctgca ttaatcaatg cctatgtgtt tgcaatggat tacttcacca caacggaagg
    30481 agcgaaagca gacaatgaat tttatacaag tgaagaattt tctttctaat tacattcata
    30541 ccgttctttt acttcttgga ttggtgtgtg tgttggttgc tatcacctta ctaacaaatg
    30601 tctactatgg cttgttagcg ctgggcatag tgcttattgg ggtagcggtc atgctaaata
    30661 cagaacagaa gggaggttaa aagatggcat tttttaaagc gagacaaaat acaacgggag
    30721 atcctttcct acaacatgtg gtatcaatcc aatcggatga ttacaccacc agctttacaa
    30781 gcgttcgtgc attaagaaat agtgatgtgt ttgcagccgt tcgaattatt gctagtgata
    30841 ttgcttcaag tccgattcaa ttggtcaaaa acaatatgcc acaagctgat aatgaactgg
    30901 tgaagttact aaacgagaaa cctaattcag aaatggatgg ttggcattta aagtttgctt
    30961 tggcggtcaa tatgttgcta aacggtaata gctttgcaga gattaaacgc aacggtgaaa
    31021 aggtagaaga aattcactta ttacctaact caagtgtaac ggttactcaa ttagataatg
    31081 gtacgttgtc ttatcagatt ggtgataaaa aaagacgtgt gaagtctagc gatattttgc
    31141 acttcaaata tttcacccaa gatggtttaa caggattacc accactttat gcgttacgtg
    31201 atgaactgaa aattcaacaa gctggcaacc gcacattgca caatttcttt actcgtggtg
    31261 tcagtgggtc aggtattttg aaggttcata agtcagattt agacggatca gcaaagaacg
    31321 caattcgtga aaagtttgaa gaagccaacg gttcaagtag tggagataat gctcttagaa
    31381 cgatcattct tgatgaaaca atggactaca aaacattaga aataaacacc gatgttttga
    31441 agcttatcaa ttccaatgat tggaacacaa aacaaattgc caaggcgttt ggtgtaccga
    31501 ttgagcgttt aggcgttgaa aatgaacatt ctagcaccgt tcaaagtaat ctccagtata
    31561 tccaaagtac gctgattcat tactttaatg tgtttgtgag tgaattagat acgaaacttg
    31621 aaaccaatat ccgctttaat tccgatcagt tactagagac tgatcctgaa acaaaagtaa
    31681 aaaatgtatt ggatcaggtc aaagggtcac ttctcacgat taatgagggg cggtcgaaaa
    31741 tggggctacc ccccatggat ggtggcgatc gtttactagc aagtttgaac tttacgtatt
    31801 tagatacgtt ggagaaatat caattaaaag aacaggaagg agttacacca gttgaataat
    31861 gaagaagaaa aggaaaaacg gctgacagaa gaagctgagc taacagccga ttctcccaaa
    31921 gtagagaaag aaaatgaaaa acaaccaaca gacggcaaaa ctatttcagg ctatgcgttg
    31981 aaattcgggc aaccgtcaaa agatttaggc ggctttgtag aagtgattac acccgaagca
    32041 ttaaaagagg tggatttatc aaatgtgttc ttattatatg gacacgatta ttcaaagcca
    32101 ctagctagtg tcaaagcagg tacgttgaaa ttgaatgtcg atgatacagg attacatttt
    32161 gaagcagagc taaccgacac gacctattca aatgatgtgt atgagaatat ctcaaaaggg
    32221 gttgttgatt ctatgtcctt tgggttcgtg cttggattag attcattcga caaaaaagaa
    32281 gatggcacaa ttgaacgatc aatagataaa atcaaagcac ttaatgaaat tagtgtcgtg
    32341 accgttcccg cttatgattc atcaaatgtc caagtaaata agcgttctta cgaatcgttt
    32401 atgagtaaca accaagcaaa acaaacaaac aatagcttag aatccacttc taaagcacaa
    32461 aaggagagta ataacatgga aaaaacttta atcgataacg aaaaaacaga attgcgtggg
    32521 tatgaagaat atatccgttc acaaggcgaa gtgcgtgatg gagtcactac tgtaaatgca
    32581 gcggcagttg ttcccgaaga agtaatcggt gaagtctttg atttgaaacg ttcaaattat
    32641 aacttagctc aatatgcaac agtaaaaaca gtatcaaatg gacaaggtaa atatccagta
    32701 gcaactaacc aacaagcagt gttagcaaca aaagctgaac ttgctgaaat tggtgatatt
    32761 gacgctgaaa tgtttacttc agttgattat aaagtagaaa ctcgtgctgg taagattgcc
    32821 ttatcaaatg aggttgtgga agattcagca gtgaatattg tacaagaggt caaagatcag
    32881 ttagcgaaat tggtagaaaa cactgacaat aagcatatca tggatttatt aaaaacattc
    32941 actaagaaaa cggctgctac gttggacgat ttgaaacaac tatacaatgt ggcattagac
    33001 ccagcattaa ataaaatggt aattctaaac caaagcggat attaccacct agatacattg
    33061 aaagattcag atggacgtta cattttacaa cccgatgtga cagcacctag tggtaaatca
    33121 ttattcggta tgccagtagt attgattgca gatacattgt ttgccaatcc taaagctgga
    33181 acattcccta tgattatggg ggatattgca caatctatct ttgttgctcg tagaaatcaa
    33241 gtaacgactc aatgggaaaa attcgattac tactcacaag gacttgcagt gatcgttcgc
    33301 aacgattata agaaaattga tcaaaatgct tcagtgtata ttgagtttac gccagttgta
    33361 acaccaaaag tatagaaaaa tattgggcgg cggtttatcc cactgccttt ttttcattag
    33421 gagagataaa atggtaattt tggatagcat aaaaaaaagt atgcggatcg atcacactat
    33481 tgatgatgac tttattcaac aattgattga tacagcaggc gaatatataa aaagtgctat
    33541 tgatagtagc gcaacggata aagatatgga taattatcag caatttgatt tggcggtgtc
    33601 attacttact caacattggt atttgaaccg tcaagaagcc agcagcgaac ggataccagt
    33661 aacggtacaa gcattagtac aacaaatgag aggtgcttat tatgccaatc attaagaatg
    33721 taaatgaatt gactgagaga gtcaagttta aaaagacaaa acgggtaaaa gatgaagatg
    33781 ggcagatggt ggatagtgaa gaaactgtat ttgaatgttg ggctaatgtg cgttcacaaa
    33841 tgctaaaaga cgtgcttgct agtgtaggta ccattcttga aggaacgttg acgtttatta
    33901 ttcgatacga tcaagattat gaactaacaa acgatatgaa agtagcttgg aaaaacaaga
    33961 gttataaaat tatttcaatc aatgaaggaa cggcgtttaa agattataca acgatcatag
    34021 ctaaacagat ttcttagaat gattacactt gtaaacgttg tgggtattta gtataattaa
    34081 ggtagtaaat gaagggttag ctgcctgaat tttgcaagac ttagctagtc gaaatctatt
    34141 gttggactga aaattgtagg tgtggttgca aacatgctgg actaagaaag atgatagatg
    34201 atgaacgttc aattttaata caggcatgct aggactgatt ggatggtttt ggcaagctga
    34261 ttgtgtagaa atcaaagaac acgtctgttg tggacgtgtt ttttttgtta taattcaaaa
    34321 gaggtgattt aatggacaaa gcagagttta caaattttta ttggaagtat tatctacatt
    34381 tagaaaatga gtttattaat accacagatt ttgtgatgct cgatgagaat aatttcaaaa
    34441 cattctctat tgaatatcaa aaactactac tagcgattgg ttcggagtgt gagattattt
    34501 tcaaagaact ttgcggattt gatagcagta gcaataaaag cataactgat tttaaagctg
    34561 ttattaaatc tagcgaatta atgtgtttgg ataatggtgt tagggttatg aattctttaa
    34621 cattgacttc actaaaacct tttggagatg ggtggcctga agatacacca gattggtgga
    34681 aaatatataa cagagtaaaa catggtcgtt cttcaaatta taaggaagca aatttggaaa
    34741 atgtgttgta tgctttagca agtctatatt tattagagga atatttgcat aagaaagtaa
    34801 tactagaagg tgaagtagac tttataagtc cagagtcaaa tctatttacg ttatcttggg
    34861 aaagaaaaca ttcgtcgatg caaaaagtga cgtttgaaaa agtggattca aattatgtag
    34921 ctccactcat tgattttaaa gaacaagaag aaatttaaaa acccccacgg cttattgaag
    34981 tttttgtatg ccatattgta tgccatttgg tttaaatcgc ttgaaaaata gtgatagata
    35041 actctaattc atttagtcat aaacgctgtt ttgataacct ttatagttct ttgatatggg
    35101 tttctcattc atggcggaag aagaagaata gaacaaaaga atgaattaat aagatataaa
    35161 aaaagggatt gtgacaaacg tcttgtcaca atcccttttt ccaaataaac gatgttcaat
    35221 cagctgcccc tcggcattcg ctcgaaaaac ggcgaaatat gaagaactat tttgccattt
    35281 gtttctctaa taatcaggtc aaaacgttga cttcacagtc tcttccttaa acggtgttct
    35341 cctgccaact cctcggtcac aagtcacaat attcaacaaa catgagaagc tgttttttga
    35401 aattgttcct tgtgactcgg agctgaacgg caggctcacg acctctttct taaacggtgt
    35461 tcaaaagctt gcatctgcgg taataagttc aaccaaacga aaattatgag gagctatttt
    35521 tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct tttcgtttag
    35581 cactaaattt ccttaaaaag tagaaaagct ttcgaagcct cgtttgtttc ttttactgta
    35641 taataaaaga aaagagtaac aatcgctaaa agatataaac aagagaaagg aaatacaaga
    35701 tgattggtct gatttatttt gtggtgatcg ttctggcgaa cacagttggc gctatttccg
    35761 ggatgggtgg aggcgtgttg atcaaaccga ttcttgatct tatcggcgcc cattctgttg
    35821 cagggatttc tttttactca acagttgcgg tattcacgat gtccattgtt tcgactgtgc
    35881 gacaagtatc aagcgggaaa tcactgaatt ggcagattgt cggttgggta tctagtggag
    35941 ctgttgttgg aggagtagtc ggcaacattg tattcgaagt ttttttacag ttatttgaaa
    36001 acgagaagca tgtgcagctg atccaaattt ttttgacggt attgaccttg gtttttgcgt
    36061 tcttctacac caagcatcat cagccaaaat ttcatttgac gtcatggact tggtacctta
    36121 tatgtggggg ggttctgggc tttttagcta gttttttagg tattggtggt ggaccagtca
    36181 atgtttcttt gttgatgctg atgtttgcat tgccaataaa agaagcaaca ctatattctc
    36241 tatctacgat tttcttttct caactggcaa aattggtaac gattgcttta acaagtagct
    36301 ttatgcgctt tgatttatct atgttgtttt atgttatccc cgctgctgtt attggaggtt
    36361 tgtggggagc aagatttagc agggttttgt ctccaaaaaa agtgaccttt atttttcaag
    36421 taattgtcct cgtggttctt ttgatcaatc tttacaatgc tttcgtcatc ttacaaacat
    36481 taggagaatc tagactaacg caagtcaaaa tcactgaaac atattgttct aaatgaaaaa
    36541 aggagtatac tgtgataaaa aaattcattt aaaaaaataa aaattggctg gtgatttgga
    36601 tgttgcggga aatgcgttta ggagatgcag aagcactacg agaaatcaat gcggaacaat
    36661 taggatatga tgtaccatta accgttacgg tgagacaaat gaagaaactg ttgaaggagc
    36721 cagaaaaaaa ttttttcttg gtctatgaag atcctacttc taaaaaagca gctggctatg
    36781 tacaagcgga gtcctatgaa tcgattttca gcgatccgat gttcaatatt atggcacttg
    36841 ctgtgtctaa acatgctgaa aaaagaggaa tcggaaaggc cttgatgact ggcgtagaag
    36901 aagcgaaaag acgaggaata tcagcaataa gacttaattc tgcagaatac agagtagaag
    36961 cacaccgatt ttatgaacgc atcggttatc attccgataa aatgcaaaaa agatttttga
    37021 aaatcctgta aatttttatc aaaaaatacc tggtcatcaa gccgatactt gatgatcagg
    37081 tatttttttt gactaagaaa gtaattgcat caagaaacct gagatgatca aaacgatggc
    37141 accaccaagc cgattgccca tttgagcaaa agcaataagt tccatccgat tagctgcaga
    37201 taagacagct acatttcctg taccacccat cgagttgttg cataagccag cagtaatagt
    37261 tgattcgatt ggatataaac caaacaaacg accgacaaat cctgaaacta ctgaaatcgc
    37321 gataacactt gtcaaacata agacaacaaa ttgccatgtc aaagcagaag ccaatacatt
    37381 tagattcaat aacgcaatac cgataccggc aagaacagct gctgtcaagt ttttgacaat
    37441 caagttgttg aacatgatag ctgcatcttc gtaatattct ggtaataggt ttgcgatttt
    37501 acagataaca acgataatga tcatgaatgc gtaagcatgg actttaggaa caaaatagtt
    37561 acagatttgt cctaagatga agaaagtcaa tgataccatc aaaccgacac ctaattgtgg
    37621 aatggaaggt tttacatttc taggttttcc atcgccaagg tcgccttttt ccattaattt
    37681 accattaccg ttgaattttg gcattgattg tcccgcacga gcaactaacg ctgcaccaat
    37741 gatagctagg acatttgtca ttgctgtcgc aggaatcagg cgggaaatga tagaagaagc
    37801 gtccgtacct aaaacatttg cataaatcgt tgataaaggt acagctccgg ctccaacacc
    37861 accagccatt gcgggcaatg agatatataa aacggaattt gcaaaaccat ttccgataag
    37921 catacctacg agtcctacgg caaaaaagga gacgaccatt gaaataagtg caacgggaat
    37981 aaaacgaaca gaagctttca tcaatagatt acggttcata ccaaggatgc taccagtaat
    38041 caaggcagca atataaaagt ctaaaaagcc catattgctg acaaagtttt ctgtggattt
    38101 tactacatac tcaggtaaga tcccaaatgt agcaatcgcg gcagaggcaa agatcgcaaa
    38161 aacggagcca ccacctaaat aacttttgac gatagggatt tttgttccga taaaatgaaa
    38221 taaattaccg aaaatgacca aaacagcgat tgggccaatc atattcgtcg gtaattttcc
    38281 taaagccatt gcaatgatca ggacaaggac catgatcaaa taaaggggca aacttacgcc
    38341 ggtaattttt gttgaccaaa acccttcttt tttcttttcc tcaactgcag ttgcggttgt
    38401 tgttttttgt gccattttta cagatccttt cttattctgt atcgtatgaa aaaagccaaa
    38461 gagaagcggc aaaagagcag tagttggctg gctgctgttt tgccgcagtc gcttttttct
    38521 ttttagacgt catacaaagt ttctgtatgt tcttttacta taacaatctt aatcttctaa
    38581 agatttatat tcaggaaccc atttagcaga ttcaacagct tctttgatat ccgtgatttc
    38641 ttcacgattc aatttttgtg caacaactga ttttgcgaca gtttcagcaa tcgtttgaga
    38701 gaattcagtg atttttgcta ctggaggcaa gatagctgct cctggttttg ttacatcaac
    38761 gattccgcct aatgctcgac tagcttgaga aatgatttca gcatttactc gtgtagctgt
    38821 tgaagcaatc aaaccaagcc ctaaacctgg gtacatcaac gcattatttg cttgaccgat
    38881 ttggtaagtt acaccgttat attccacatc agcagcaggg atacctgttc caactaaagc
    38941 ttttccgtcc gtccattcaa tcaaatcttt tgcttttgct tctgccaatt ttgttggatt
    39001 agacaaaggc atgatgattg gacgtggggt atgagccgcc atttctttca cgatttcttc
    39061 agtgaatgct ccaggttggg tagaagtacc gatcatgatc gttggatgga ttgcttttac
    39121 aactgcttct aagtttgtca attcatcagc attagtgaat tctgagcgtt tacgagcgaa
    39181 tgggatttga ccaggagtca atccttttgt atcttcaaac aataaaccct gtttatctac
    39241 ttgatagaaa tgttggcgtg cttcttcttc aggtacacct tgacggatca tttcatctaa
    39301 aaggatgttt gcgataccta caccagcagt accagcacca aatgtcaaga tcgtttgatc
    39361 tttcaattgc tcacctgata tattcaatcc acctaataca ccagctagta caacgattcc
    39421 tgtgccttgg atatcatcat tgaaagtagt gattttatct tcgtattttt ctaagatcgt
    39481 tgcagcattt cctcgtccaa aatcttccca atgtaataac aattctggga ataattcagt
    39541 agctgattga acgaattgat caatgaattc gtagtaagtt tcgccttcta cacgagcatg
    39601 acgattccct aagtataatg gattattcaa taattcttcg ttattagtac cagcgtcgat
    39661 tgatacaggc aagacttgtg caggattgat accagccgca gcagtgtaga ccatcaattt
    39721 accgatagcg atgtcaacac cgttcacacc ccagtcaccc atacctaaga ttccttctgc
    39781 atctgtcaca acgatcaaac gaatgtcgcg tccatctgct gcgtttttca aacttgcttt
    39841 gatattttct ggttcgtcga ttgaaagaaa tgcagcatct tgtggtttca agaaaatttc
    39901 gttgtattgt tcgattgaat ccgcaacgac aggatcataa acgacaggca tgaattcaac
    39961 taaatgttcg cccatcaatt tataaaacaa tgtccggttc gtattgaata gattcattaa
    40021 gaagatacgt ttttccaaat cggtctgttt gcttaagtat tgaccgtaag cttggacaga
    40081 ttgttgttcc aatgtttgga cagtacttgg aagcatacca gtgattccgt attttgcccg
    40141 ttcttctttt gtaaaagctg ttcctttatt tagaaaagga ttatttaata agtttagccc
    40201 tgtaagcatg aatgattcct cctaagtttt aatacaaacg aagtatagga gtcagatgag
    40261 gatatagtca aaaagagcag gtataataaa ttttatttat atgagtaata gagtcaaaag
    40321 aaatcaaaat agcggtattt gttcttttta tatcaacaat ccttgcttga ttactatgcg
    40381 tatctcttat atgctaaaga aagaaaagta gaagaataaa ggatatgtta gatagataaa
    40441 tagaatctct gaagaataaa tcacgtgatc gtgacgataa aatacactta cgtcaggtga
    40501 taaaaaatac ataagtagaa aactaagagg aggaacagaa aatgaaagaa gttcaattga
    40561 tcagaaaaag cgaactatca gaaggtggtt gcaatgcatg cggcgtagta gaagcaacaa
    40621 gctatacatt aaagcttggt gccaacaaag cgataatctc tgagttgaca gtaggcggtc
    40681 ttgtggacag tctggcgctt gctgaaggtt ttattggaga agatatttat gagatgtttt
    40741 cagaaatccg tcagttaaaa aaaggggaaa actgcataga ggttcatcat gagagcccga
    40801 atgtgagatt caaacgtggt gataatgaga tgatcttcaa taatcatgtg tccgatcaca
    40861 ccgagctata tggaatcgtg aatcaaatac taactgagct ttttggattg ggaccttatg
    40921 cgttcaagga agaaaacggt aatccaaaat taaacgaaga atggcaagaa acgattgaaa
    40981 tacaaagaaa caacccgcac ttatttcaat aggcatccac agtatttcgt aaaagggact
    41041 ttgacacgac ttttgtcaaa gtcccatcgt tttttatcta tttgtgttct aaacatttct
    41101 ttcagagtag taacaactgg aatgactgaa atgtaaacag attatttgcc tgtatcaata
    41161 cggaagagta atataaagtg tgtaaacgct atcatattat tcattcaatt ttttatagag
    41221 ggaaggcatt gaaatggaaa aaacgtatca agcaggtaca aatgaaggaa tagtggattt
    41281 tatcaatatg gaagatttag aaatagccgc ttcacaagtg attccagctg gtggttatgg
    41341 ttacatcagc agtggtgctg gcgacttatt tacttatcaa gaaaatgaac gggcattcaa
    41401 tcatcagctg attattcctc atgtattaaa agatgtagaa ttacccgata caactacaca
    41461 ttttgacaaa gaaacgctga ctgcaccaat catcatggca ccagttgctg ctcatggctt
    41521 agctcatgtg aaggcggaga aagcttctgc aaaaggtgta gcagattttg ggacgatcta
    41581 tacagcaagt tcttacgctt cttgtacatt agaagagata agagaagcag gcggggagaa
    41641 agcaccgcaa tggtttcaat tttatatgag caaagatgat gggatcaatt tggatattct
    41701 tgaagtggcc aagcgtaatg gagcaaaagc aatcgtattg acagcggatg caacagttgg
    41761 cggaaaccgt gaaacagacc gcagaaatgg gtttaccttc ccactgccaa tgccgatcgt
    41821 tcaggcttat caatcaggag taggccaaac gatggatgct gtgtacaaat cttccaaaca
    41881 gaagcttagt ccaaaagatg tagaatttat tgctgctcat tctgatttgc cagtctatgt
    41941 gaaaggtgtc cagtcagaag aagatgtcta tcgttcatta gaatctggtg ctggcggaat
    42001 ctgggtatct aatcatggtg gccgtcaact agatggtggt ccagcagcgt ttgattcgtt
    42061 gcaatatgtg gcagaagcag tagataaacg tgtaccaatc gtgtttgaca gcggtgtacg
    42121 acgcggacag catgttttca aagcaatcgc atcaggtgca gatcttgttg ctattggcag
    42181 acccgttatt tatggattgt ctttaggagg aagtacagga gtccatcaag tgtttgattt
    42241 ctttaaaaca gaattggaaa tggtcatgca attagctgga acacaaacag tagaagatat
    42301 caaaaaaata aaattgcgtg agaatcgttt tatttaagaa acaaatgacg aaaaaaatag
    42361 gagtgcggca gatgatgccg tactcctatt tttatagttc aaggatgtca ctaatagaat
    42421 aatttgaaac gaaaaaataa aattgaaata ttttttcata cttaataaaa aaggaagaat
    42481 attcatgtaa acgattttat tgtttttttc tcttttatac aaaaagggtc ataatttcaa
    42541 gtaagcggat gaattcatga ggattttttg catactgtct ctactatact taggtcacta
    42601 agaaaaagga gtgatttatt atgaaaaaga acatgattgg gacattatta ctttcaacac
    42661 ttcttctagg cggcttggca acaccagctt ttgctgaggg tcaagcgact tcaaaaggag
    42721 atattacctt tactgaacca acaaataccg tggagcctct taaccctact gatccttcaa
    42781 aaccagtaga gccagcagat ccggaaaatc cagcaactgg ccagacaggt cctttaacac
    42841 tggatgtagt tcccgaattg ccatttggta cacacgagat tgaaagcgga acaaaaacgt
    42901 atcaagtaga cgcttcaaaa aacgatacac cttatctcca agtatcagat cgtcgaggtg
    42961 taggtgcaga tggccaagca caagggtgga acgtgacagt ttcggtttca gattttgtaa
    43021 acggttcaca agttttgcaa ggcgctgaat tagattttgg aacatccact gttaaaagta
    43081 cgtcagataa cgaatccact ggaccaacta gtcaaactgt aactgggttg agtaaagcaa
    43141 gtgcagcgac accaatattt acagcagcaa aagatcaagg tctgggaaca tggctttctg
    43201 tttatgatcc agcaaatatc acactgaaag tgccgaaagc agcagctgga acattcacgg
    43261 ctgatttgac ttggaacctc gtggctggcc cagtagcata gagtatgaaa taaattcaac
    43321 aaactgcggt gaaaatacta taggtgaagg attttttacc gcagtttttg ttgaaaggat
    43381 gtggtggaca atgaatcaaa gtaaacgact gtttgtttcg tttttttcta ttttaagtct
    43441 atttttcatt tttccgtcaa tcagccaagc aaaggattca gcaggagact ttggaatcaa
    43501 accggtattt ccagagaacc aaatagataa agcaatcggt tattttgatt tattagtggc
    43561 accggaacaa aatcagacac tagaagtaat tatcagcaat tcttcagatg aagaacgaac
    43621 atttgaggtc tctgtcaatc cggcggtaac gagtgatggt ggaacgatcg attatagtca
    43681 aaaaaaccca acgttagatg agacattgcc gtttgatgtc cgtgacgttt tgctcattgc
    43741 gaaaaaggaa atcaatgtat cagcacatgc agaaacaact gtacctatag aagtgaaaat
    43801 cccagcaaaa agctttaagg gacgtgtatt agcgggtatt catgtttcac ctaaagaaga
    43861 agctgaaaca gaaaatgcta cagaaggagc acaaatcaaa aatcgtattg cttataatct
    43921 cgcagtcgtt ttacaagaaa gtcaagagac gatagaaccg gatctgaaac ttttatcagg
    43981 agatttggac gaggtcaacg caaagccaac tgttcagctt cgtttccaaa atcctcagcc
    44041 taggattatc agcaatttga tatttacgag caagatcttt tatgaaaatc agctttatat
    44101 tgaaaatacg tctaatgcat ttttagttgc accaaattcg aattttcact tgaatcttga
    44161 tttagctggt gataaagcaa aagccggcga ttaccgcgca gaaatcatag caaaatcagg
    44221 cgacagtaat gaatggcgat ttacacaaaa ctttacgatc aaaaaagaaa aagcacaaaa
    44281 agtaaatgaa aattccgttt ttgcagtaca agaacaatct ttcccatggc tttatgcagg
    44341 attggttgct gcagttctag tgttatggtt gattttgctg tttttgtggg tccacaagaa
    44401 aaagaaaaaa ggagaaacaa catgatgagg tgatttcgtt gaaaacatcg atcttattgg
    44461 gagggattat tgcaagtttg ctgttcttca gctggcaaga gccagtccaa gcagatacca
    44521 aaagttcagg tacgattaca ttttatgatc taagtccaat tccgcatcca agtggttcag
    44581 tcaatggcgc atcaaaacag cagacacagc taccgattta taaagaatct aatcaacatg
    44641 gcgtattccc ggagacgaat gaacaaaaga tccgttttct ttatttgatc attggtatag
    44701 aattatggct tcttgcgtgg ttgttgttat ggagaagaaa ggaaaaggag gatgaacatg
    44761 ttgctacaaa ataaattttc attttttcgc tccttctttt ttacttcgct ttttgtttta
    44821 agtatattta tcttttcacc ttcggcagaa gctgttggag caacgcctcc tgccatttct
    44881 tatgatccat acacgtatga aaatatcgta cctccaaatg gtggacgtag tgcagtcaat
    44941 ggcgggaagc ttgtccaact aactggggct aaccaattgc ctaaattgac tgctacttat
    45001 ttgaacgatg gttcaaatga tccttggaaa ggtggcacgg tccgttttca ttgggaaagc
    45061 catgtgaaac taacaaatgt acttgatttg gtgaatatca ctgcacaagg atttgcattt
    45121 gtggcgatca tcaatttgcc ggaacatgta tcaagcagtg atgtattaaa agcaattgac
    45181 tggaacaacg cctacttgta tattgccggt gcccccatca aggttactag cggaagttta
    45241 ttatcagcag gaagccatac cttgcgtttt gggatggggt cgtgggatac aaatactcta
    45301 ttgacagata ttattgctat tattacgcga ggcgaattca acgtggacga tatcccgctt
    45361 caatttgatg ttacagctaa tgtcgcgaag atgacagaaa acggagataa atatgatacg
    45421 agtccaaaca aaattttgac caagggtaaa ttacaacctt ctatgtctaa aaaggccgtt
    45481 ttttctgttg atttttatga ttcgaataat attatccaag atcgtatgtt caattcgatt
    45541 ttagctccag ctgcaggtag attttatcct aaattaactg gcggaaactt gaatccagga
    45601 gcatatgcat tttctgcaag tgcagagata aatacgtgga atagttacat ctcaccaagt
    45661 gattcaacag gaaaatataa tacatttgct gataccacag aatacgtgga tggaaataac
    45721 cagaaccttc caggctctac caatagtcgg acattgacga tggggctgac tgaaggacgt
    45781 tttgatcagt tgccatttag tcgctttgat cgcgtagtca actattttac aggaaaaaac
    45841 gttacacaag gagcaatact gactcatact ccagcaagca caagtggatt gaatcagaca
    45901 gccaatatcg tgtacagtgg gaaagatgcg caaggcggat tgctttctcc tgttgcttta
    45961 aaggtattgg agcagtacaa gctagacgga acggttttac caacaaactt aacagccgat
    46021 agtcagtggg gaaagctcct ttcttctgca tcgtaccaag tcacggccaa ttggtcagca
    46081 actgaactaa aaaagggttc gatccattac aggctttatt cgaaaggaac ccaaaaatta
    46141 gcgacaggat ggacagatca acttttccaa acgatccaat caaataacgg gggtgtaaat
    46201 acagctactt ctacactacc tgcattggct tcagggcaat attattttga ttatcgcttg
    46261 gtggacgatg tacttactaa catgtatccg tcttttgcgt acaaatggca gtctgaacaa
    46321 gctggaatca ccactcttcc tcaaataaca gtggctaatt ttccatctgt gagtgcagat
    46381 agtcagctaa aaaaccttag cagacaacct gagacaggag atcccctgtc tgctctatca
    46441 ggagatacga ttcaagaaaa tgtgacattc acgttaacaa aatctgggga tgcgataacc
    46501 gacaaaaaaa tcacgatctc acttcctgaa aatactactt atatcaatgg ttccttaaaa
    46561 ttaaatggta caactatcgc agataccggc attcaacaag gagtttctgt cccagcagat
    46621 ctattgagca aaataggaga taccattcat cttacttaca actatcaatt aaatactgta
    46681 gatacttctt tacaatccgt cagcatactg acaaaggcag ctgtactttc cagcaatatt
    46741 acattagcag atggtgctaa gcttcctaac ccagttgtcc aaacatctgc taaaacaatt
    46801 cttgtcccca aacaagaatt aacattagtt aatgtaccag atgattttac atttggtaac
    46861 gatctcccca aaccgttgaa gacaagttat tatgaatcaa aaggcgattt ttcttttgat
    46921 gtgcgggata ctcggcttcc aagcacgtct ccttggcaac tgacaggtac attgacttct
    46981 ttatttaaga atgatcaagg tcaagaatta agcggaacaa aattatactt caatcattct
    47041 ggatcaaagc aattgattca gcaaggtcaa aacacgttga tttatgagag tgatggaaca
    47101 gctaaaggag aggttctcgt tgactttccc gataccgatg gtttactctt agaggtaaat
    47161 agcagtacga atgctcaacc tggcgcaacg tatcaaggca tggtcacatg ggaactgaca
    47221 gctgggccaa ccagctaagt gattagaatt tgtatggatc tgtgataact gtcacagatc
    47281 ctctttttca aggatgagaa ggaaacttct gctgttaaaa tcagaaatgc ttgaaggagt
    47341 ggacttggaa cttttcagtt tgcttgaaaa aaatgaacaa cggcaaatca aacttttcca
    47401 acttttatta gaggaaaaag gagaggtttc cgttaataac gtacttaccc gcttatcagt
    47461 tgatcgggct accttgaaag aagatctgtt ttatttacaa gctaacttgg aaaatatcaa
    47521 acaattggaa attgttatcc aagaagggaa tattttatta atcagacatg gaaatatagc
    47581 agcagtcgat gtttattatc attgttactt gcgctattct acaaaatatc agatacttct
    47641 ttatctgttg gaaaatggct catttgatcg gcagaaactt gtcatggaac ttaatatcag
    47701 ttcggctact ttgtctcgca gagtgaagga attaaatgat tctttaaatg agtttcatct
    47761 gaaaataaaa agcgggcggc tgaccggtcc agaaagtcaa attcgttatt tttatttcca
    47821 attattttgg tttggacgtc cctatcttga aaacaaaaaa gaatacagtg atttatcagg
    47881 aaacactttt ttagatctgc tgcaaaaaga gtttagtttt gctattacag aagaaggacg
    47941 attgaaattt gaaatatggc tttccattat gaagaagcga atgcgctgta cgaaaaaatc
    48001 caaaccagat tatagcaatc ttcctgttgg attgtttcaa acgacacaat ttttattgga
    48061 cctccataca tttttgaccc gttacttctt tcaatatgcc tttccttgga atcaaaatga
    48121 aacgttggtt ttttatcttt tcatgatcag taactttaca ttagatacac ataactcgca
    48181 tgtccaggag tttttgataa gcgaaaaata caaagacgac gtagtagctc aattgaatcg
    48241 aacgtttaaa caatcgatag aagaatattt ctctttttat gtttttccag aagagatttc
    48301 gcaaaagatt gcgttgacag tgatgcaaaa tcacgctcat tttgcctatt ttagaggatg
    48361 gatgaatatt tttggccaag aaggattaaa acagcggtta actgaagtag aagataaaca
    48421 attcctggtt ttatgtgaaa gattggtcag acaaacattt gctattgttg attttactga
    48481 agtagacgag gaaaatgccc gctttgaatt atttgctcgc tatgcatcta ttttacggac
    48541 gctgatcaag cagttagaat tacgtctgca aattgcttat gatcttcctt atgaaaggct
    48601 aatggcggat atcgtgaaag aaatcatcca ggaacaattg ctgaatacga tcaaatatga
    48661 tttagtcgaa tacgagaaag aaaagcagta tgatatcatt ttgactagcc aattgaaaga
    48721 gtacccgtca cagaagtccg ctaaagtttt tgtattcact agcaacgaat ataattatga
    48781 tttcccctat ttgaaccaat ttttaaaaga atgttattta gaaaaattga atttaaggat
    48841 gaataaaaca tgaaaatcgt gatcattggt gcttcccatg aaggcatcac agctgcccta
    48901 aatctaagaa aacttcaacc gaaagcagaa gttttactga tcgatgaaga tcataaagat
    48961 ggactaggct atgtttcaaa tggaatcaac ctttatttaa aaggaaagat acgtagttta
    49021 gctgaagttg cccataacat gcggactctt caagaaagtg gggcaaaact gatcaccgaa
    49081 tggagagtaa ctgaacttga tccagacaaa catcagctca tcctcgcatc caaagaagga
    49141 aaaaacgaga ccataaccta tgataaatta atcgtagcga caggttcctc tcctgtcacc
    49201 ttgtataaac aaattgaagc tgaaaatgtc tacacctata aaaatctagt gcaatctaag
    49261 caagtacttg ccgctttaaa agaagcaaaa gaagtagtga tcttcggtgc tggttacatt
    49321 ggattggaat tagcagatgc tttgagaaat aaaggataca ttattcatct agttgattat
    49381 atgccgaatg ttttatcaag atatttcgat aaggatatga tcaacagttt tcaaaatcag
    49441 ctgcaaacta agcaaataaa tttttatcca aatgaattct tgatcgattg gaaaaaatca
    49501 gaagagaaag tagtatccgt acaacttctg tctcaaacaa taaaggcaga tatggtcatt
    49561 ttttctgccc aaactcgtcc taatacgaca ttgttaaaag aaaaagtggc tttgtatgag
    49621 gatgagactg tgatagtcaa tgaatatctg cagacaagtg atccggacat ctatgcgatt
    49681 ggagatatcg tcccagtcag ttttgacaaa aataaacggc atctcttttt acctttagtt
    49741 actcgagctg tacatatggc aagagcagta gcgctaactt tgagtggtca gccaaccgct
    49801 tacgacctca gacaaaagat aacagcagca gtcattatag actacttttt aggaactgta
    49861 gggctgacag aagatgaagc gccattcttg gaacaaaata ccggttcgtg ttcaggagaa
    49921 tttgatctat ttccacaata cgacgaagaa aacaaaacag taaatgcaaa gctgatctac
    49981 catccggata cattagaaat aattggcgga cagctgataa gccaagaatt cttattatca
    50041 gatttgaacc tgcttgcgga tatcgtgaaa cacaaaacta cgattccaca gctagcagtt
    50101 gaggattttg gatttctgtc tgaatacacc tctcgttttc actacctcaa tgagttagct
    50161 tttaaagtac tagctaagag agcaaatagc aatagagtag ataaaagact gtgagaaata
    50221 tcacggtctt ttattgtgtg gggatataat aaatattaat caatcgagaa taaaaaattc
    50281 atataatgaa atagcggaag aattttttga gcataatatt cgccaaaaat ttatcaagtg
    50341 ataaaattgt tgtataaaat gattatttca ggaggaggag ttaaatgttt ttagcattaa
    50401 atgaaattat gcattcaaag ttacgttatg cgttagttgc aggggtgatg tttttgatcg
    50461 cctacctggt attttttttg actgggttag cttatggctt agctcaagat aatcgaacag
    50521 cagtcgacaa gtgggaggca gattcgattg tgctttcgaa agatgcaaat tcaaatctag
    50581 ggatgtccat gattactaag aagatagcag aagaagtcga aggtgggaaa gtggcgtatc
    50641 ttgcccaaac acctggagtc gtgactagta aagacagtac agaagaagga aaaatcaatg
    50701 ttagcttctt cggtatcgat aaaaatcaat tcatcatgcc caatcttgtt gaaggaaaag
    50761 cttttgataa cgatgatgag gcagtaggcg atattagttt gaaagaagaa tatggtctag
    50821 ccataggaga tacagttaag ttatctggta gtgacaagac gtttaaacta actggcttta
    50881 cggatcatgc caaattcaat gtctcaccag ttctctatac aaccatcaat gcttaccaag
    50941 aaatccgctt cgaaaaagaa gatacaagtg aaaatgcacg gattaacgca atagttgtca
    51001 gaggtaaaat cagtaattta cctgaagatt tagaacagat caaaatttct aaattcatca
    51061 atgaattacc tggatataat gcgcaagtat tgacttttgg atttatgatc ggatttttga
    51121 tcgttattgc ggctattgtg atcgggattt tcatttatgt actgacgatg caaaagatta
    51181 atatctttgg tgtaatgaaa gcacaaggga tcacaggagg atttattgcg cgttctgtag
    51241 tggcacaaac attcatttta tcatttgttg gtattcttct tggtctatta ggaacagtgg
    51301 gaacatccct tgttctacct gatgcggttc cattccaaag caattggctg ttttttggcg
    51361 tcattagctt gttgatgtta gtagtagctg tgttaggcgc actattttct gttcggacaa
    51421 tcgtaaaaat cgatccgttg aaggcaattg gataagaagg aggaagaaca tgaaagcaat
    51481 agaatttaaa gaagtagaaa aaagtttcca agatggcgac caagtagtta aagcattgaa
    51541 agaaacaacc atgagtatcg ataaagggga atttgttgca atcatcggtc cttctggttc
    51601 aggtaaaagt acttttttga ctttggcagg cggattgcag acgcctagca gtggctctgt
    51661 atttatcaat gatcaagaat tcagtaatca aaaagaaagc gaacgcgtta aactacgttt
    51721 taaagaaatt ggctttattt tgcaagcttc caatctggtt ccttttctga cagtaaaaaa
    51781 gcagttatta ttagtagata agattaaaca tgaacatcgt caaaaagaag caaacgaatt
    51841 atttgagcag cttggcgtgg ataagttgat caacaagtat ccagaagaac tatctggtgg
    51901 agaacggcaa agggtcgcaa tcgctcgtgc attgtacaat gatccgtcca ttattctagc
    51961 agatgaacca actgctagtt tggattcaga aaaggcacga gaagtagtcg atatcttggc
    52021 aaaagaatca aaagacaaaa ataaagcaac gatcatggtt actcacgata cacggctgat
    52081 tgacaaatgc gatagaatat ttatgatgga agatggtgta ttgaaagaaa aagaataacc
    52141 aaaaagcagg tggaaaaatg gtccatcgat acaacaaaga tacacagcaa aaaattttga
    52201 aagaagcgac tgacttgttt atgtccaagg gatatctcgg cacttcaaca agagaaatcg
    52261 cacaaaaagt tgggatcacc cagcccaatc tctatcatta tttcggtgat aaagaaaaac
    52321 tatatacggc agttttagaa aaccacttaa aagatgttgg aaaagctttg agagaaatcg
    52381 ttcaaacaag cgaaacggga tttcaagtaa ccttgacaaa aatggcgcag tttttgattg
    52441 agacacatct ggtcgatttg tttctgatgc ttcacgatct tgaaagcaat ctttcaaagg
    52501 aaacaagaga tcatcttttc tttctatgga agaaaaatta tcgtgaacct tttgaagaaa
    52561 tcttttcagc aaaccaatct gtgctaagaa atgggatttc aaaagaaatc gcagcaaggc
    52621 attttttctt agtgttagca ccttacatca ctcggtcgaa aagacctgtg gaagaaccgc
    52681 taaatgtggc gcaattgatc gatttatatt tgaatggtgt attaggagaa gcgtaaagct
    52741 gttatatagg gagaaaatag ttaggtgaag aagcaagata tgacgaagat cgttatatct
    52801 tgcttcttta tataggtagt ttttcataaa tacaaatttg ttattctctc atgattatca
    52861 gggtatattt ttatttatta tgtcggtgtt ccaggaagtg ttttaattta ataacgaaga
    52921 aattaattgt ttgtagaatg aaggaaacta tttattgggt agatgaatca ccacgaatag
    52981 tcaaaaggag atttcaggat atgccaaaaa tgaaaaaaat cattttagca gtaatgttat
    53041 tttctacggt tatatctttt acagcccctt ttttgcttac ttaagctgat tttaagtttt
    53101 ggcccttagt ctggatctac gaggtgagag tcaagaatga aaaaaataat tggagctttt
    53161 gtatttgcaa tcattatcat tattatctgt tttcaaatag atgtttttgg tcaaaaaaag
    53221 atagttggac aaacggtcag cagtacgaac agtacggtta caaagacaaa ggaatcattt
    53281 gatgatacag aacaagagac attaatcaaa atcggaaaaa atgaccgtac actatataca
    53341 gatgactcgc taactacccc acttgcaact ataaacggcg gagagctggc ggagtttctt
    53401 tctgaaacaa aaaatgctta tcagatcaag acaaatgatg gctatactgg atatttagcc
    53461 ctcgaagatg gaaccaaagt cacaaagaat atacaaacaa aaccggaaga gctatctgat
    53521 gcagtgattg tattagatcc tgggcatggc ggaaatgata ctggggcatt aagcaatgat
    53581 gaacaaacag aagaaaaaga tataacatta agtacagcca taaaagtaaa aaaggcgcta
    53641 gaggatgctg gagcaacggt ttatttgacc catactacag atgaattagt acagcttgga
    53701 gatatatgcg actacagtga agaaaaaaag gcagatgtct ttatcagttt acacgcagac
    53761 tctacggaat atgcgaatga agcaactgga atcacgacat attattacta tggacaagag
    53821 gaaacattag cacagacaat tgctgactcc ttcactgatc tgcctctgga ttcaagagga
    53881 atctccactg ggaactatca agttcttcga gaaaatcttc aaccttctat tttaatcgag
    53941 atgggttata tgaataatga tagtgattta aaggaattag taacagacag ttatcagcag
    54001 cagattgctg caagtttgac acaagcattg accacttatt ttcagtaata aataagccca
    54061 gccaaacaaa aatagctcct catatttttc gtttggccgg gcttattatc gcagatgcaa
    54121 gcttttaaac accgtttaag gaagaggtcg tgagcctgcc gttcaactct gagtcacaag
    54181 gagcaatttc aaaaaacagc ttctcatgtt tgatgactat tgtgacttgt gaccgaggag
    54241 ttggcatgag aacaccgttt aagaaaaagg ttgtgaaatc aacgttttgt tctgagtatt
    54301 agagaaacaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    54361 atcagatgat tgaacaccgt ttattcggaa caagggactg tgacatgact tttgtcacag
    54421 ttccattatt tttttagtag cttcaaagct ttttctgtat tggcaaaatg aagtttggca
    54481 tatttttcaa gcataggcat gccgcctttc tccaatagtt ttgccgctac ttggtcagat
    54541 ttcgttccag ctcctgacgg aagggtgatt ccagcttcag ctgatgcttt gtctaactct
    54601 tccaaaaagc tggcacgact gatgatagaa gcagcagcaa cagctaaatg atattgttct
    54661 cctttagtaa cgaagtacag tttttcttgt aattgatttt tttctaaacg cgcatatttt
    54721 ttaaaatttg cttccggcgt aaactgatcg atcaaaatcg cttctggttt ttctggctcg
    54781 atttttttta gcagcaaatg gatcgcttga ttgtgcaaag cgactttcat ccgaacggca
    54841 ttgtattttg gttggatctc attgtatttt tctggagata agacaagcag tttatagggg
    54901 atggtttttt ttaagatgtc agcaagctgg atgatttggc tatcttttaa ctcttttgaa
    54961 tctctaacac caagtttacg taattctgca agctgatcac gtttcacata agcagcacat
    55021 actgttagcg gaccgaaata gctgccattt ccgacctcat cactacctaa aacggataat
    55081 tgactgatat tttttggcaa agaagaggct gtttttgctg gcttggcttg tttatcctgt
    55141 gcctcccccc atttatcagc ttctattgct gcattcgtac cttgaaacat cacttttccg
    55201 gatgtataag cggtaatggt cgtcccgtct ttttttgcag caaagctagt ataaggaatc
    55261 tgtttattta acaaataaga gcgatagtat gctttcattt gactaagttg gtcgtttgtt
    55321 gctttgataa tgacgttgct cataaaattc tcctcgtttt tatacataaa actataccgc
    55381 aactcacgac ttttcgtttt ctaagagatt gcgagacata gcattttttt aaagtttatc
    55441 atataatagt taagtatgtg aaaaatattt gtggagaacg gtgaaagaac caacttcatg
    55501 gtacactaaa taaaactttc atcaaatagg aggaaatgat tcgtatggcg cacgaaaaaa
    55561 cacgctacaa agcggtgatt gccaaccaaa catatactat tatcggacgg gaaaccaagc
    55621 atcatatgga tatcgtaacg aagctgatca atgaacagtt agcagaattg aaacaattat
    55681 caccacaaat ggataatgaa caagcagcaa tcttgatggc tgtcaatgcg ctttcggatc
    55741 aattgaagaa acaagaaaga atattggagc tggaagaaga aacagcagaa ttaaagaaaa
    55801 aaatgatcaa atttacagag cttgaaaatc gtgtgaaacg cattgaagca atcgagaacg
    55861 aagctcggga agtattgaaa gaaaatggtc aagcagatca taccattaaa aatcatgtgg
    55921 aagcacaaca gattttaaac gagaaacgaa aaggacaaat taaacaaaaa tcttctaatt
    55981 aagatccttt tatcaaaata agaaaaattt aaaaaagtta gaagagaaag gaacgtagca
    56041 tgctgagttt gctgatttta tttttattgc taattgcgtt tttttctgga gcacgtcgcg
    56101 ggtttgcttt gcaaatcata ttcgcgattg gatatgtatt gtcatttatt gctgcccagc
    56161 atttttacaa accattagca agtcatttgg aattatacat tccataccca gctgtcaccc
    56221 caacatcaaa gttagcattt tttgatcagg tatttgcctt tcacctagat gaagcttttt
    56281 atgcaggaac tgcttttctg attattttgc taattggctg gctgcttacc cgatttgtgg
    56341 gggtttttgt ccatggattg acgtatgtgc cgatcttgag acaggtagac tggattgcag
    56401 gaggcatcct gtcactaatc atggcttacg ttactatatt tttgattttg cagttacttg
    56461 cctttgttcc attagatgtg gtccaaaatc aattcggcga gcatagtttc gctcgtttta
    56521 tcgttgagag aacgccattt cttaccaaca agatgtatga gctttgggta acgaatattt
    56581 tgaattaagg aaaatagtgc tggaaaatat ttcgtttttt gtacagagta gtttatttaa
    56641 gaaggctgcg tagcgtatgt ccggcacagc tcttttttca tagtgaaaga taaggtgata
    56701 aaatgaataa ccgaatcctt gaaacattgg aatttgaaaa agtcaaacag atggtcagac
    56761 aatttgtagt gactgcacaa ggaaaagaag aactggcaga attggtacca gtgagtgaga
    56821 aacaaacgat cacaaactgg cttcaagaaa ctgaggatgg attgaaagtg caacgtctgc
    56881 gaggcgggat ccctatacct aaaattgaaa atatccgtcc ccatatgaaa cggattgaga
    56941 tcggagcaga cttgaatgga gtggagcttg cacaagtttc cagagtattg tctacgacaa
    57001 gcgaattgaa tcgtttcatt gatgatcttt ctgacagtga aatcgaattt gcacgtttgt
    57061 atatgtgggc agatcagtta gtcacgatcc ctgttttgag ccgccgttta aaggaagcaa
    57121 tcgatgaaga cggacgcgtg actgatgacg cttctcctga gttaaagagc ataagacaga
    57181 acattcggcg aagtgaacaa gctgttcgtg aacagttaga tgggatcgtc cgtgggaaaa
    57241 atgcaaagta tttaagtgat gcgatcatca ccatgcgaaa tgaccgctac gttatcccag
    57301 tcaaacaaga ataccgcggt gtatttggcg gtgtagtcca cgatcaaagt gcttcaggtc
    57361 agactttatt tattgaacca aaacaagtgg tggatttgaa taatcgtttg cgtcaatacc
    57421 aaatcgctga acgaaatgag attcaacgta ttttaagtga actttctgct gaacttgttc
    57481 cccatcgtca agaaatcatc cacaatactt atgtgattgg taaaatggat ctgatgaatg
    57541 caaaagcacg atttggtaaa gaagtaaaag ccatcgtgcc gggaatcagt gaagacaatc
    57601 atgtcgtctt gaaacaagca agacatccac tgatcgatca ggaaaaagta gtttctaatg
    57661 acatcacaat cggaaaagac tatcaagcca tcgtcattac aggacctaac acaggtggga
    57721 aaacgatcac gttgaagact ttaggtctgt tacaactgat ggggcaagca ggattaccga
    57781 ttcctgcagg tgaagaaagt caaatcggta tttttgagga agtatttgcg gatataggag
    57841 acgaacagtc gattgagcaa agtctatcga ccttttcttc tcatatgacg aacactgtag
    57901 atattttatc aaaagtcaat gaaaaaagtc tggtattatt tgacgagctc ggtgcaggaa
    57961 cagatccgca agaaggtgct gctctagcaa tcgcaatctt agatgatctt ggtaaaaagt
    58021 ctgcttatgt gatggcaaca acgcattatc ctgaattgaa agtttatgga tataatcggg
    58081 caaatacgat taatgccagc atggagtttg atgtggatac attaagtcca acgtatcgtt
    58141 tgctgattgg cgttcctgga cgaagcaatg cgtttgaaat ctctagccga ttaggtcttg
    58201 atacagaagt tattgatgaa gcgaagcagt tgatgaatga tgagagccaa gatttaaacg
    58261 aaatgatcac agatttagag aatcgccgga aaatggcaga gaccgaatat ctggaaatgc
    58321 gtcattttgt ttctgaggca caagaacttc acgatgattt gaaagaagct tacagctatt
    58381 tctttgaaga acgtgaaaaa gaaatggaaa aagcaaagaa aaaagcaaat gaagtcgtgt
    58441 cagaggcgga agaaaaagca gaaaaaatca ttgctgatat tcgtaaaatg caacagcaga
    58501 ttgggcaagg aaatgtgaaa gagcatcagt tgatcgatgc aaagacccaa ttagcaaatc
    58561 tacatcaaga agaaactttg aagaaaaata aagtattgaa gaaggcgaaa gaacaaaaaa
    58621 cgttgaaacc gggagacgaa gtgttggtta cgacttacgg ccaaagaggg acgcttttac
    58681 gtaaaaacgg gaatcagtgg caagtagaaa tcggtatatt aaaaatgaat gtgtccgaag
    58741 acgagctgac gcctgttgct cctcaaaaag agccgacaca acgagttatc catgctgtac
    58801 gatctgaatc tagtagtcac gtgccgaatc aattggacct tcgaggaaaa cgatacgaag
    58861 aagcgctaag tgaggtagat caatatttgg attctgccat tctagctggt tatcctcaag
    58921 tgactattgt ccacggaaaa ggaacaggcg cacttcgcaa gggaattact gattatctta
    58981 aaaaccatcg gagcgtcaaa agctttgagt ttgcaccggc aaaccaaggc ggaaatggtg
    59041 cgacaattgt taaatttaag taaagcttac taaaggtaag cagatggttc gctatccaag
    59101 tatagaaatg ctatactagt catagatttt aaaaatggag gtctttgata tgtcacaagt
    59161 aattacagat aagacattta atgaagaaac agataaagga cttgtattga ttgatttttg
    59221 ggcaacttgg tgtggtccat gtcgtatgca agcaccgatt ttggatcagt tggaacaaga
    59281 atatgatgaa gaagaattca gaattgctaa aatggatgtg gatgaaaatc cagaaactcc
    59341 tcaacaattc ggtatcatga gcattccaac attaatgttg aaaaaagatg gtcaagtagt
    59401 agaaaaagct gttggtgttc attcaaaaga acaactacgt caaatgatcg atcaatattt
    59461 ataaaaactt acagcaaaaa taagctgagg gtgggactga atccagttcc gtcctcggtt
    59521 tttttgcggt tgagttaagg ttattcaaat taatattttt tgagtataat tacgttgtca
    59581 ggctggattg tttttttgac agacatgcta taataacttt aattgaatat gaaggggagt
    59641 accagatgaa cgaacgaatc aaaaacaaat tagctttact tcctgatcag cccggctgtt
    59701 acttgatgaa agataaaaat ggaacgatca tttatgtcgg caaagccaaa atattaaaaa
    59761 atcgtgtccg ctcatatttt actggtagcc ataatacgaa aacggaacgg cttgttagtg
    59821 aaatcgaaga ctttgaatac atcgttacag aatcgaatat cgaagcattg ctcttagaga
    59881 tcaatctgat aaagaaaaat gatcctaaat acaacattat gttaaaggat gataaaacct
    59941 atcctttcct taagataacg aatgaaaaat atccccgttt ggtgattact cgtaaggtac
    60001 taaaagacaa agcactgtat tttggaccat atcccgatgt cggtgcggcg aatgagacaa
    60061 agaagatcct cgatcgatta tttcctctga gaaaatgcaa acctagtcag acgaaggagc
    60121 cttgtcttta ctatcatttg ggacaatgcc tgtgtcctta ttatttcgac gtagatccga
    60181 aagtctatac gaaaatcgtt gatgaagtga aaaacttttt aaacggagga cacgaaaaaa
    60241 tcgagtcaga gatccatcag aaaatggaaa aagctgctga aaacatggag tttgaaaaag
    60301 ctgcagaata ccgagaccag atccgtgcca ttgagacaat catgactcgc caaaaaatga
    60361 caaatactga tttactggat cgagatgtat ttggttatgc gattgataaa ggatggatgt
    60421 gtgtccaagt gtttttcgta agacaaggaa agctaattga acgagatgtt tcaatgtttc
    60481 ctttctataa cgaagcagaa gaagatttct tgacttacct cggtcagttt tatcaggaaa
    60541 atgagcattt cattcctaaa gaagtcttga ttcctgatac gatcgacaag cccagtgtag
    60601 aagctttgtt agctacgaaa gtgctgcaac caaaacgagg agaaaagaaa aaattagttg
    60661 aattggcgag taagaatgcc tcagttgctt tgaatgaacg gtttgatctg attgccagaa
    60721 aacaggaacg gacgatcgga gcagttgaac gtttaggaaa cgcgatgaat atcccgaccc
    60781 caatacgtat cgagtctttt gataactcta atatcatggg gacgaatcct gtggctgcga
    60841 tggtcgtatt cattgatgga aaaccggcaa gaaaagaata tcggaaatat aaaataaaaa
    60901 cagtcaacgg accggatgat tatgcatcaa tgagagaagt catctatcgc agatattcgc
    60961 gagtgattcg cgaagggttg cctttacctg atttgatctt gatcgatgga ggaaaaggac
    61021 aagtagatgt ggcaaaagat gtcttagaaa atcaattagg aatcgatatt cctattgctg
    61081 gcatggtaaa aaacgataaa cataaaacaa atgagttgct attcggtaca gatttggctg
    61141 tagtaccgct tgagcgaaat tcaccagagt ttttcttact ccagcgaatc caagatgaag
    61201 tccatcgatt cgcaatcact ttccatcggc agctacgcag taaaaacagt tttgcttccc
    61261 gattagatga aattgaaggg ttaggaccaa aacgaaaaaa aatgctgctt aaagagttca
    61321 aatcgttgaa aaatatcaca gcagccacga cagaagaatt acaagaaatc ggactgccga
    61381 aaaatgtcgc acaaaacgta tttgataaat tacatcagga atgaggaaag ggcactttac
    61441 aaagaaagta aagtgtccta tcattttatg tacaacaaaa agagcgttta cgttttgttg
    61501 gtaaataata aatcgcttac gtctggtgtc taaggatata tgtgatttct tgaagaagga
    61561 gtgaagaaat gttagaagtc aaggatcttg ttaaaacttt tgggaactac acagctgtcg
    61621 atcatgtctc tttccaaatc cccgatggaa aaatcatggg gctaattggc caaaacgggg
    61681 ctgggaagac aacgactttt cgtttgatct tggatttttt gacacaagac caaggagaag
    61741 tgttatggaa tggccatcat cttggggaga aagattatga tgtcatcggt tatcttccgg
    61801 aggaacgggg actttatccg aaagtaacga ttcaagacca actgctttat tttgcagaac
    61861 ttagagggaa atcaagaaaa gagattgaac caaaaatcga cttttggatg gaaaaatttc
    61921 aggtaaaagg gaaaaagacg gataaagtaa aatctttgtc taaaggaaat cagcaaaaag
    61981 tccagctgat cgccacgtta atccatgaac ctaaattgat cattttggat gagccattca
    62041 gcgggttaga tccggtaaat gctgaattgc taaaagatgg aatattggaa ttgaaaaaac
    62101 atggttcatg tgtcattttt tctagccaca atatggataa tgtagaaaaa atctgcgatc
    62161 atttgatcat gttgcgaaac ggaaaaatgg ttttgaatgg aaaagtacat gagattcgtg
    62221 aatcatttgg ccgtacgaag ttattcttgg aatctggttt aagccaacag gaagtagaag
    62281 aaatcgaagg cgtgaaaaaa gtgatccttc atgaagacaa tacgttagag attaccttag
    62341 aagatcctga agctgggaaa gaaatcttta ctcgtgcgac tcagttcggc tacattccta
    62401 tgtttaacca gcaaccgcca actttggaag agattttcaa attgaaagca ggtgaaatcg
    62461 atgcgtaagt tttggattat taccaaagat gtctatttaa aaaatgttaa gtcgatttct
    62521 ttcttgatca tgatattagt cccttttatc atgctgggta tcatttatgt agcaggaaac
    62581 tttgctcaac aaaatagtga tgtcaataaa atcggcgtat tggctgataa tgagcaaatc
    62641 agtcagcaaa tgagccaagt caaaacagat gattttgagt tcaaagcagt tgattctgaa
    62701 gaaaaagcac aaaaagagct ttcggaagaa aaaatcgatg cgtatttagt agtctcaact
    62761 gagaatgata agataaatgg gatgctttat agcgaaaatt cattaggaca aagtacacaa
    62821 ctactgatac aacaacaact gactggcttg caatcgatgc ttcgagcgag tcaattaggc
    62881 atttcaccag aagaagtagc tagcttgagc caacaagcaa gtttgactcg acaaaaagtc
    62941 aattttgatt caaaaggaaa aatgacagtc ggagaagata actcgacagt ccaatacgtc
    63001 gtaagttatg tagcaacgat tgtcttgttc attattattt tgacgtatgc gcagatcatt
    63061 gcacaagaga tcgcttctga aaaaggcacg cggatcatgg aagtgatcct gtccagtacg
    63121 actgcacaaa agcattttta cggaaaatta acaggtgttt tacttgttgc attaacgcaa
    63181 atggcattat acggtattat ttttggtata ggatacagtc aattcaaaga tatggaaatg
    63241 gtcaaaaata tattagacgg tatctcattg gataacttga ttggaccatt cttgtggtat
    63301 tctcttctat tcatgatctt tggcattttg attttttctg ttttagcagc tttatgtggc
    63361 tctttggtca acaaagcaga agatacagca aaagcaattt tgccagtgac ttatctatct
    63421 ctaggcggat acatgcttgg attgatacta ggagcttcag atccaaacaa tatcgttatt
    63481 cggatcactt cgtatattcc attcttatct tcatatatta tgccgattcg cttagcaaat
    63541 gagacagtcg gtatgggtgg agcattgatt tccttgttgg tacttgtagc cgtaacattc
    63601 ttattgatga tcttgtctgc aaacatgtac aaatcgaatg tactcgttta tagcgaaggc
    63661 ggattatgga gttcattgaa acaatcgatt tcaattatga ggaatgaacg aaaaaaagca
    63721 taaaacaatc ctaaaataca gaaggaagct ggacatctat tgttcccagc ttctttttgt
    63781 atagacctat tttatttatt ttactatatt ggatatatat tcattgaaaa tagtgtataa
    63841 caactttata atattgagta taccaatttt tggaggcgtt ttaatggacc gttatttaga
    63901 tttactttca gaaaaattcc cctcaacgga ggatgtcatc acggaaatca tcaatctcga
    63961 agcaattttg cagcttccaa aaggaacaga gttatttttg agtgatatac atggcgaatt
    64021 tcctgctttt gatcatattc tgcgtatcgg ttcaggaaat cttaaagaaa agatcaaaga
    64081 ccttttttct gaacaaatga cggaaacgga tatcagccaa ttcactattt ttacggctta
    64141 tccagaatat gcattaacga ctgattggta caaagaacaa gataaatcgc agctgatcca
    64201 tcatttgatc gatcttttac ggtttacgac agtcaaatat acccggtcaa aagttcgaaa
    64261 aggattgccg aaagaatata gctatatcat tgaggaactc ttgtatatcg atgaccgtat
    64321 caatggaaaa aaagactatg taaaaaaaat cattgaacaa cttgttttga tgaaggaaga
    64381 agaaaaattt ttaacgaaac ttgcacagac gatccaaaaa tctgtcatcg atcatttgca
    64441 tatcgttgga gatatttttg accgaggaac tcaagcagcc aaagtgatgg atcgaatcat
    64501 ggatttttct tctgtagata tccaatgggg aaatcatgat attttgtgga ttggtgcgta
    64561 ttgcggctct gaggcatgtt tactgacact tttacggatt gcagcacgct ataattattt
    64621 atttgaatta gagaaagaat atgggttgaa tttacgtcca ttgttttctt ttgctcatca
    64681 aacttatcag aagaatccag tatttgcgcc taaaaacagt aaaaatctat ccgaaagaga
    64741 gcaagaagaa ttagaaaaaa tccatcaggc actttctatc cttcaattca aatcagaaca
    64801 tcagttattg gatcgtcgac ctgaatttaa aatggacgat cgtaaattgc tggaaaaaat
    64861 cgactatgaa gcatcaacga ttgatttaga aggtcagctc tatgagttga aaggaacttg
    64921 ttttcaaacg atccagccag atgatccaaa aaaattcttg gaagaggaac aaaaagtgat
    64981 tgatagtttg atgtattcat tccagcactc tttgagaatg caaaaacata tgacgttttt
    65041 gatcgaaaaa gggggaatgt atctcacgaa caatcagcat gtgctgtttc atggctgtat
    65101 acctgtagac gagaagggac agctcttagc atttgaatta gaccaatctt atcgcggaaa
    65161 agaactgctg ggcttttttg aaaaacagat aactgaaagc gcaaaagatc tgactgcaaa
    65221 agaagattta gcaaccgatt tgatttggta tgcgtggagt gggccatttt cgcctttatt
    65281 cggcaagagt aaaatggcga cttttgaacg ttattttctc acagagcctc atacgcacgt
    65341 cgagaaaagc aatccttatt atcacttgcg agatgaagag tggttcagtg aaaaaatttt
    65401 agcagaattc gacacaaaag aagaagggtc agcaatcatt aatgggcaca cgccagtaaa
    65461 agtaaaaaaa ggggagtcac cgatcaaagc aaatggaaaa gtatttgtca ttgacggagg
    65521 tttatccaaa gcttatcaaa aaacgacagg aattgccggt tattcactat tatgcaattc
    65581 ttatggtttc caaatcgtga cacattatcc gtttttgcct attgaacaac aatttgcaaa
    65641 aaaatccgac caaacaaatg tgaaaaaagt aatcgaacag caactaccac gcaaactcaa
    65701 tcgtgataca acaaaaggta tggaactgca gcagcagatt acccagctca aaaggctgtt
    65761 ggactatcga aaggacgatt gagaagaatt ccagtgaaca ttgttccata gactggagac
    65821 tgagacaaaa gtcgtgtcgc agtctctttt tccggataaa cggtgttctt ctgccaactc
    65881 ctcggtcaca agtcacacta ttcaacaaac atgaaaagct gttttttgaa attgctcctt
    65941 gtgactcaga gttgaacggc aggctcacga cctcttggta taaacggtgt tcaaaagcca
    66001 gtttctcggt attaagccaa atttatgcaa aaatgtgaaa agccattttc acaaaatttt
    66061 tcttaatact cgaaactaaa cagctttttc acaaccccct cagaaagtct attaaaattc
    66121 attcacaaag aaatcgaata agcgctgttc agatggatgt acacggtggg taagttccgg
    66181 atgccattga acaccgagga ttttatgcat atcatctttg ctttgaaccg cttcaacgag
    66241 tccatcgtta gaaaaagcga tggcttttaa taaaggtgaa agatctttga ctgcctgatg
    66301 atggtaagaa ttcacaaaat atggatcggg gagaaggttg cttaacaaac tgtctgaaac
    66361 aatcttgact tcgtgagtcg taaattgcgg ggcagtgggc tgttgttcat gttttactga
    66421 ccactttgga tataatgaaa gatcttgata aagtgtacct tccaaaacga cattcaatag
    66481 ttggagtccc cggcagactg caaaaattgg ttttctttgt ttcaatgctt ccaagatcag
    66541 tgcctgttca aattggtctc gttgaatatt tgtttccgtt agctttggat gaggatcttc
    66601 catgtaaagt tgtggactga catcttgacc acctgcaaga ataagtttgt cgatttgtcc
    66661 aatcagttga ggagctgaat ctggagacat gactggcaga ataagaggca atccttgagc
    66721 atctaaaact gcatccacga atccttgcgg tgtatagctc acttgatttc cttggaaagt
    66781 atctgttgct cgaatcagtt gatttccggc aatgccgatg attggtttca tttgtattcc
    66841 ccctaaagta gacttattgt aacaaggatt taaaaaaaat taaactatgt aagacttgcc
    66901 cctatactta tctgttcttg ctgtgttact atctgtaaag agaaatttcg tgtgaaattc
    66961 atgacgatag ttgaaaatat tgcttaattt gttataataa aaagtaagca gaaataaaaa
    67021 ggttgggcgt aagcttcaag gatctagttc ttcaaggggt gagaaggaca ttttattgaa
    67081 ggggcctgcc tatactaagt tatctttaga ggtacatact ttcaatgaaa aaagaaagca
    67141 tgtacctctt ttttaaatcg aaaggaagtg aagcaagtgt tagaagcttt ggaacaaatc
    67201 cgaaaagcag aagaagaaaa tgaaaagcgt gctcaaacac tgcggcagca gctgaagatc
    67261 tatgcaacag aaaaagagca ggaattggaa acgatccaaa caaactatcg acaacaacta
    67321 aaacagttgg tggaagaaaa agaacaattt gaaatacaag aattagaaaa agaaaaaatg
    67381 aaattgaaag cagaagcaga caaggtgcaa gcaactttga aagatcaata tcaaaagcat
    67441 cagagtcaag cgatcggtgc gatcattgaa agggtgaaag aaacttatgg ccgtcactaa
    67501 gatggaaaaa gtgaccctca tttcagataa aagaaatcag gagaggattt tacaagcagt
    67561 acaaggaatc caaaacgttg aaatccggga tctgtatcaa aatagaacaa acaaccagtg
    67621 ggtggagaag tattttccag ataccacgat tattgataaa gaagcaaaat taagcgcttt
    67681 aggtaatcgg ttgaaagaca tccaagaagc tatccaattc atacaacacc acggcgatag
    67741 ccgtcaaaag aaactccatt tgaaacgtca agaactttcc ttacaagatt tggaagccaa
    67801 ttattccgaa gaaaatttca taaataaatt gaaagaagtc cttgatttaa aagaaaagtg
    67861 ggaacaacta actgaagaac gtgatcgttt agaagaagag gaagaatggc ttcttcattg
    67921 gcaacagctg gatattgctc caagtatgta tgcaagtaag acgaccattt ttgagatggg
    67981 gactgtgagt gcagcaaatt ttgaaagttt caaggaagaa ctgagtaagc ttgatgacgt
    68041 ttatatggaa gaaatagatt atacgccaaa acaagtttat ctttcgtatg ttgctttaaa
    68101 aaaatcagtt gctgttatag aagaaattgc tgggaaatac gggttcaata aagaaacgta
    68161 tccttatgaa caaaatccta aagaaaaact gcaagagacc aagcagcaat tatccattgt
    68221 tcacgagcag caaaagaaga taacgacagc gttaggtcag tgcagtggct atatccaaga
    68281 atttgaatgg gtagaagaag tcacacttgc cgttgcagaa cgagaaaaaa taaaagaacg
    68341 gtttatccat gcgacttatc tgatcgtttt gcaaggttgg gtagatgcag aagaaaaaca
    68401 gaatttgctg catgtgttaa acgaaaccgt atcagaagaa gatatatacg tcagtttcga
    68461 aacaccaaac tcagaagaga ttcagcagga agtccctact aaattgaaaa accatccgct
    68521 tgtcgaacct tttgaattgc tgactgaaat gtacagtctg ccaaaatatg aagaagtaga
    68581 tccaacacct tggatgacac cattttatct tgtcttcttc gggatgatgg tcgcagatgt
    68641 tggttatggt ttgctgatgc tcattgggac aatactagct caaaaactac ttgttctacc
    68701 acgcgggatg aaacgtttcg taaaattctt tgagattctc tcgataccat cgatcatctg
    68761 gggattgatc tacagttcat ttttcggaca gtcattacca aaagaactgt ttggcatccg
    68821 cttgcctttc ccaatcctat ctacgacgga tgacgtcaat acgattttga ttttatccgt
    68881 gattttcggt ctgatacaga ttttggttgg attatttgtg gcagcaaagg aaaatatcag
    68941 gagaaaagat tacttgagtg ctgtcagtga tggatttgcc tggcaaggga tcctaattgg
    69001 gatcgttatt gcgttggttg gtgccatgtt gataaaaaat acagcatttg tttaccttgg
    69061 cgctgggcta tcgatcattg ctgccttatg tatcttgatc gttccgatta tccaaacgcc
    69121 gtctaaagtc aaaggtgctg ccaaaggtgc gtataatctt tacggactga ccggctatat
    69181 cggtgattta gtcagttata cacgtttgat ggcattgggt atttcaggcg gaagtattgg
    69241 agcggcattc aatatgctag ttgctttcat gccgccagct gctcgattca gtgtagggat
    69301 ccttttgatc atcgctttac acgcactgaa tatgtttttg acactgctaa gtgcctatgt
    69361 ccatggcgca cgattgcagt atgtcgaatt ttttgggaag ttttatacag gaggcggacg
    69421 tgcctttgat ccgctgaaaa cggcggaaaa atacgtcaac atcaatcaca agaaaaaaaa
    69481 caataaataa ttggaggatt tttatataat gatggattac ttaattagtc aaaatggtgg
    69541 aatggtattt gcggtattag cgatggcaac agcgacgatt ttttcaggga tcggttcagc
    69601 taaaggtgtt ggaatgacag gtgaggcagc agcagcattg acaacaagtc aacccgaaaa
    69661 attcgggcag gctctgattc tgcaattgct tccaggcacg caaggtttgt atggattcgt
    69721 tattgccttt ttgattttta tcaacttagg aaatgacatg tcagttgtac aaggactgaa
    69781 ctttctaggt gcttctctgc cgattgcttt tacaggcttg ttttcaggta ttgcccaagg
    69841 aaaagtcgca gcggcaggta ttcaaatttt agcgaaaaaa cctgaacatg ctacaaaagg
    69901 aatcattttt gctgcgatgg ttgaaacata cgcgatttta ggtttcgtta tttccttcct
    69961 attagtgttg aatgcctaag cataaaggag gaaaagcaga tgaacgccat tgaaaaaatc
    70021 atctctcaga tgaacgaagc agcagagcag gaaagagcgg cgttagaaca agaagagcga
    70081 atgaagatcg atcaaaactt tgaacaaaaa cgtacgcaag ttgaaacaga acatcaaaaa
    70141 caaaaagaaa aacaaatcga attactcgaa aaaaaatacc gtcagctaag gaatcgccag
    70201 caagtagaag tacgacaaga aaatttgaat gcgaagcagg aatttttaag acgattgttt
    70261 gcagatgcgg taactgaaat ggaaaattgg gatgaatctg aacaaatcca gtttatcaaa
    70321 aatgcattgt attcattacc tttgacagga aaagtagcat tcattgctgg agaaaaatca
    70381 gcagcctatc tttctcagac gttgttggat gaatggaaca atgaacttcc ctttatgatg
    70441 gttttaagtg atgaaactgt tgctgatcaa gcgggttttc tgataaacga tcaaggagtt
    70501 cagtataatt ttcttttcag cagccttgta caagatatcc aaggaacgat gagttttgag
    70561 attgccaatc aattattcga ataaggaggg atcagtgtat ggaataccac gaactaaatc
    70621 ccttgattcg cggaagagag cttgaacttt tgtccaatga gacatttgaa cggatgattc
    70681 aaacaaattc tgtcgaagca cttggtgaaa tattgaaatc cacgatttac agtccatata
    70741 tttatgacgg atatgaatat gacttcgaac agaatctttt aaaggagcag agccgtctat
    70801 ttcgctggtt aaaggaatca gcaccggagc ctgaaatcgt ttggatctat acgatgcgtt
    70861 atactttcca taatctgaag gttttgacaa aagctgagat gacaaatcaa aatctggacc
    70921 atttgtatat cgacgatgga ttttattcat tagaaacctt gaaggatgcc attcatacgc
    70981 aagtttcaaa tgaacttcct gaaagcatta tggacagtat acgagaagta cgtgattatt
    71041 ttgaagagtc taccattctt cagggaattg acgtgattta tgatcgacag tttttgacag
    71101 agcagcgacg gcttgccgat aagctaggat atcaagaatt gctgacagaa gtcattgctt
    71161 ttattgactt gaccaatatc acaacgatgg ctcgaggaat attgcagaaa agaacatatg
    71221 ggttcatgac gacggtactt tccagctcgg gaagtatcga aaaagaagta tttttgaact
    71281 ttgtagataa agatatggaa gattacacga attttctatt agagacagat tatgctgatt
    71341 ttctgcgccc tgtcatccgt gagggaaata ttgatctcgt aaagcttgaa cagttgaaag
    71401 atgattatct aagttcattg tatcaagaag cacaaaccca ggctttcgga ccactgccac
    71461 tactagcctt tttgaacgca aaagaggtag aaagcaaaaa ccttcgttta ctggttatcg
    71521 gcaaaagaag ccatttcgaa tcagaaacaa tcagaaagcg ggtgagacaa gtctatgacg
    71581 cataagatcg gtgtagttgg cgacaaagat tctgttttgc cattcaaatt gtttggcttt
    71641 gatgttcgtt atggtacaac caagcaaacc gttcgtcagg caattgaaga aatggcaaag
    71701 aatgagtatg gcgtgattta tgtcacagag caatgtgcag cattgagccc agaaacgatc
    71761 gaacgttaca aggaacaaat gatacctgct atcgtattga ttcccaatca tcaaggatca
    71821 ttagggatag ggctggaaga aattcaaaaa aacgtagaaa aagcagtagg tcaaaatatc
    71881 ttatagtatg aaaaggagat agaaattttg caaattggaa aaatcataaa agtctccgga
    71941 cctcttgtaa tggctgagaa catgtctgat gccagtatcc aagacatgtg tctagtggga
    72001 gatctaggag ttatcggaga aattatcgag atgcgtggcg atgtggcgtc tattcaagta
    72061 tatgaagaga cttctggaat tggtccaggc gaaccggttc gctctactgg tgaagcttta
    72121 tctgttgaat taggaccagg gatcatttca caaatgtttg acggaatcca acggccatta
    72181 gataccttta tggaaatcac acaaagtaat ttcttagggc gcggagttca attgcccgca
    72241 ttggaccatg agaaaaaatg gtggttcgaa ccaacagtag aagccggaga aacggtgagt
    72301 gctggagatg ttatcgggat cgtagaagaa acaaaagtta taaaacataa aatcatggtg
    72361 ccaaatggga taaaaggaac gatcaaaaca atcgaaaaag gttcattcac tattgatgaa
    72421 acagtatgtg tcattgaaac cgaaaatggt gacaaaaatt tgacgatgct tcaaaaatgg
    72481 ccagtaagac gtagtcggcc aatcaaagaa aaattaaacc cggatgcacc catgatcact
    72541 ggacagcgag tgattgatac attcttccca gtgacaaaag gaggagcagc agctgtacct
    72601 ggtccttttg gtgcagggaa aacagtcgtt cagcatcaaa ttgcaaaatg ggccgatgtg
    72661 gacatggttg tctatgtggg atgtggcgag cgtggaaatg agatgacgga tgttttaaat
    72721 gaattccctg aattgattga ccctaataca ggagaatcgt tgatggaacg tacggtattg
    72781 attgctaata catcaaacat gccagtagca gctcgagaag cttctatcta tacgggaatc
    72841 acaattgcgg aatatttccg tgacatgggt tatgacgttg ctatcatggc agactccact
    72901 tcacgatggg cagaagcact tcgtgagatg agcggacgtt tggaagaaat gcctggtgat
    72961 gaaggttatc cagcttatct tggttcacgg cttgcggaat actatgaacg atctggaaga
    73021 gtcattgcat taggatcaga aggtcgcgaa ggaagtataa ccgcaatcag tgctgtatcc
    73081 ccgtctggag gggatatttc ggaaccagtc acacaaaata cattgcgggt cgtaaaagta
    73141 ttctggggtc ttgattccag tttagcccaa aaaagacatt ttccttcgat cgattggata
    73201 caaagctatt ctctttattc aacagaagta gggaagtata tggatcatat ccttcaagct
    73261 gactgggcat ccatggtcac cgagggcatg cgtattttgc aggaagaaca gcagctgaat
    73321 gaaatcgtgc gtttggtagg gattgattcc ctttcagata atgaccgtct gacattagaa
    73381 gtggcaaaat ccattcgtga agattatttg cagcaaaatg cttttgatga tgtcgataca
    73441 ttcacttcaa gagagaaaca attcaaaatg ttgaagatga tcttgacctt tggtgaagaa
    73501 ggacgccgtg cgttgtcgtt aggtgcttat ttaagtgaga tcatggacgg taccgtatcg
    73561 attcgtgaaa ggatcggacg aagcaaatat atcccggaaa cagaattaga aaaactagat
    73621 caaattattg gtgaaatcaa gcaaacgatg caaacgatcg tttcagaagg aggcatgagc
    73681 aatgattaaa gaatatcgta cgatcggtga agtcgtcggt ccattgatgg cggttgaaaa
    73741 agttgctggt gtcaaatatg aagaattaat cgaagtccgt atgcaaaatg gcgagattcg
    73801 tcgtggacaa gtattggaag tccaagaaga taaagcaatg gtccaaatat tcgaaggaac
    73861 aagtggtatc aatttacgtg actcttctgt acgattttta ggccatcctt tagaactagg
    73921 tgtatcggaa gacatgatcg gtcgagtatt cgatggtttg ggacgaccga aagataacgg
    73981 accagagatc ctgcctgaaa agcatttgga tattaacgga gaagtaatca atccagtagc
    74041 tcgggattat ccagatgagt ttatccaaac aggtatctct gcaatcgatc atttgaatac
    74101 attagttcgt gggcaaaaat taccagtatt ttctggctct ggtcttcctc ataaagaatt
    74161 agctgctcag atcgcgcgac aagcaacggt actcgattca tcagatgatt tcgccgtagt
    74221 ctttgctgct attggaatca cttttgaaga agctgaattt ttcatggaag attttcgtca
    74281 aacgggcgca atcgaccgtt ctgtcatgtt tatgaattta gcaaacgacc ctgcaatcga
    74341 acgtatcgct actcctcgta tggctttgac tgctgcagaa tatcttgctt atgaaaaggg
    74401 aatgcatgtt ttggttatca tgacagacat gaccaactat gcagaggcat tgcgagagat
    74461 ttctgcagca cggcgagaag ttccaggaag aagaggatat cctgggtatc tttacacgaa
    74521 cttagctact ttattcgaac gagcaggaag aatccgcgga ctaaaaggat cggttactca
    74581 aattccgatt ctaacaatgc cagaagacga taaaactcat ccaatccctg acttgactgg
    74641 ttatattaca gaaggacaga tcatcttgac tagagagctt tacaagagtg ggattcagcc
    74701 accaattgat gtactcccgt ctctttcgcg gttaaaagat aagggaactg gacccggaaa
    74761 gacaagagaa gaccatgcag ctacgatgaa tcagcttttt gcagcctatg cacaaggaaa
    74821 acaggcaaaa gaattagccg tagttttagg tgaatctgct ttatctgatg tagacaagat
    74881 ctatgcgaag tttgctgagc ggtttgaaaa agaatatgtc aatcaaggat tctacacgaa
    74941 ccgttcgatt actgaaacac ttgatctagg gtgggaactg ctatcgatgt tgccaagaac
    75001 cgaattaaaa cgaatcaaag acgacatgct ggacaaatat ctgccagaag ggaagtgagt
    75061 tctgatggca cgattgaatg tgaatccgac ccgcatggaa ttgactcgat tgaaaaaaca
    75121 gttgacaact gccacaagag ggcataaatt attaaaagat aagcaagatg aactgatgcg
    75181 tcaattcatc ctgttgattc gaaagaacaa ccagctgcgt caagaaatgg aagagtctat
    75241 gacagaagca atgtctgatt ttgtattggc aaatgcttcg atcacggaac ctttcatcga
    75301 agaattattt gttttgccgg cggaaaacgt tgatttgtct atcgtagaca aaaatatcat
    75361 gagtgtaaaa gtacctgtga tgaattttga atatgatgaa cagctgacag acacaccttt
    75421 ggaatacggg tatttgaatt ccagtgccga actggatcgg tcaatcgatc ggtttactac
    75481 cctgcttcca aaacttttgg aactgacaga aatcgaaaaa acttgtcaac tgatggcgag
    75541 tgaaatcgaa aagacacgtc ggcgagtcaa tgcattagaa tatatgacga tccctcaatt
    75601 agaagaaacg atctattata ttcgtatgaa gctggaagaa aacgagcgcg cagaagtaac
    75661 aaggttgatc aaagtaaaaa atatgggtac cactgactaa gtggtatctt tttttaaaag
    75721 aggaaaacga tgattaaaca aagcaaacaa ataaagaaac gtttgccggc tgttcagctt
    75781 ctcgcattag gattttttct cctgatttta gttggcggcg gcctacttac cctaccattt
    75841 tttagtaata gtgggcatgg gacaaatttt atcgatgcgc ttttcactgc aacttctgct
    75901 gtctgtgtaa cgggattgac aacattgaat acagcagagc attggaacag tgctggtcaa
    75961 tttttgatca tgcttttgat tgagatcggc ggtcttggtt ttatgatggt tccgattcta
    76021 tgctttgcat tgataaagaa gaaagtcagt ctcagcacac gtattatatt aaaagaagcg
    76081 ctgaatctag aagaagtatc aggtgtgatg aagctcatgc tttacatcct aaaattggcc
    76141 tttgtgatcc aattgattgg tacggttgct ttatcttttg tatttgtgcc tgaatttggc
    76201 tggttgaaag gtatctggta cagtttgttc catgcaatct ctagtttttg taatgcaggg
    76261 tttgatttgt taggagacag tttagccaat caccagcaaa atgtttattt gatcatggtg
    76321 gtatctgctt tgatcatttc tggtgggtta ggcttcatcg tatggcgtga tttactggaa
    76381 tatcatcaga aaaagaagat gacgattcat tcaaaaatcg cattaaccgt tacaggtacc
    76441 cttttattag gcggattcgt tgtgttcttt ttcacagagc gcaatggggc aacgctagtg
    76501 gaagggaata tgtttcaacg attggcaaac acctttttta tgagtgtgac acctagaacg
    76561 gctggatatt attcagttga ttacctccat atgagccatg caggtctgat tttaacgatg
    76621 tttttgatgt acatcggcgg aacatctggg tcgacggccg gcggattgaa aacaactacg
    76681 ttaggtgtgt tgctgatcca gatgcgttcg atgttgaaag gacgtacgag agcggaagca
    76741 tttggccgta ccatccgaca aggcgcagtg ttgcgggcac ttactttatt ttttgttacg
    76801 ttgacgttgt gtgtagtcgc catcatgatt ttatcggtga ctgaaacgat acctaaaact
    76861 tctggcatcg aatatattgc ttttgaggtc ttctctgcgt ttggtacagt aggtcttacg
    76921 atgggattga cgccagactt gactgcaata gggaaattga tcattatagc gcttatgtac
    76981 attggacgag ttggtgtatt gactgtggtc ttctctctga tgacaaaagc acaaagaaca
    77041 caatcaaaat acaaatatcc agaagaaagt gtcatgattg gataatttca tcttctgaca
    77101 gaaacctagt gatttagtaa aataagaaaa taaaataatt tttcttgctt cttggatact
    77161 ttaagtgcaa aatgttcgtt tattttttga ggcactaccc gttgttgaac ctcgggtagt
    77221 gcctcttttt tattgaaagg aatcaataag atttgattcc tttatttatc aataggttat
    77281 aattcatatt tttttatttt ttcttttacg atacttagtc cagaagctaa aatttcaagg
    77341 ttattagagg atagggaaat tcgaacgaat gcatctggtt gcgcacgtgt agtaaagcgt
    77401 ctggaatgat aaagtcggat accgttagca agaaagtcat tctcaattat cttagggtca
    77461 atctcaggat caactggaag aattcgatag taagggacac gattcgttgg tttttctact
    77521 ttgaaaagag aatcaaaaag ctgattggct ctttttgtaa gacttaattt agtttctaag
    77581 atcctatttg cttcatttga atggaggatt tgagtgatga cttccacatc taatccagaa
    77641 gttttcacat ttatattaaa aattgcttgt tctatcttgc tttggacatg tactggaact
    77701 acaagataag caactcgcaa tccagaacaa ataaattttg tcattccagc taagtagatt
    77761 gtttggttag gtaataaatt ttggaaagga ggaatgatcg tatgttgata gtaagttgtt
    77821 aaaaatgaat ggatatcatc ttcaataacc catagacctt ctttttcaat cacttcggct
    77881 aattgctctc gtcttttgtg agagatttga aaccctatag gattattaca agaaggcata
    77941 agaaagacac catgaatctt cttttttcta cattcctgaa tcaatatatc aggtcgcatt
    78001 ccttgctcgt caaaatcaat tggaacgatc tctaaatgat ataactgagc caattcaatg
    78061 aaattagcgt atgtatatcg gtctgttgct attctatcac ctggagagaa aagtgcagaa
    78121 agtgtgatag ccaatccatt ttgaacaccg gaaacaatag atagagattc taaggacgga
    78181 atgactcctt gagtttttaa ccaatttgct gcagtagtca attgaaaatt tgtgcctttg
    78241 ggatcttggt aattaagcaa accaacaaga tttgggttat tactagttga ttgaataaac
    78301 gggacaacga atttattaca ttcttcaaaa gaactaacca gaccaaaatc aatgatatgt
    78361 tcggttactt cattggtaga gatggtgatg gactcaaaga cattgggaga aataaatgtg
    78421 ccacttccaa tattcgtata cagcaaacct ttctcaattc catatttata agccttgcca
    78481 acggtagtaa aatttaaatc taaataatca gctagctctc tttgggaggg taactgagtg
    78541 tttttctgta atttattctt taaaatatct tgttctaatt gttgaatcaa cgatcgataa
    78601 taaggacgct tcaatttttg tttgtctggt cgccaagtta acgggtaatt gtcataagaa
    78661 ttaataggca ttttctccac tccttaaaat tgtataccat acaattttac
//
LOCUS       DAZAOD010000005        75935 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000005 DAZAOD010000000
VERSION     DAZAOD010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 75935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.005"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(255..734)
                     /gene="rlmH"
                     /locus_tag="ACHDPO_000356"
     CDS             complement(255..734)
                     /gene="rlmH"
                     /locus_tag="ACHDPO_000356"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFN3368020.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            1162..2451
                     /locus_tag="ACHDPO_000357"
     CDS             1162..2451
                     /locus_tag="ACHDPO_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFN3368021.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(2490..3095)
                     /gene="ytpR"
                     /locus_tag="ACHDPO_000358"
     CDS             complement(2490..3095)
                     /gene="ytpR"
                     /locus_tag="ACHDPO_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFN3368022.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(3300..3764)
                     /locus_tag="ACHDPO_000359"
     CDS             complement(3300..3764)
                     /locus_tag="ACHDPO_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFN3368023.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(3786..4106)
                     /locus_tag="ACHDPO_000360"
     CDS             complement(3786..4106)
                     /locus_tag="ACHDPO_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFN3368024.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(4250..5329)
                     /gene="pepA"
                     /locus_tag="ACHDPO_000361"
     CDS             complement(4250..5329)
                     /gene="pepA"
                     /locus_tag="ACHDPO_000361"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFN3368025.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            5529..5879
                     /locus_tag="ACHDPO_000362"
     CDS             5529..5879
                     /locus_tag="ACHDPO_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFN3368026.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            6102..7049
                     /locus_tag="ACHDPO_000363"
     CDS             6102..7049
                     /locus_tag="ACHDPO_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFN3368027.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(7106..8524)
                     /gene="pepV"
                     /locus_tag="ACHDPO_000364"
     CDS             complement(7106..8524)
                     /gene="pepV"
                     /locus_tag="ACHDPO_000364"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFN3368028.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            8673..9518
                     /locus_tag="ACHDPO_000365"
     CDS             8673..9518
                     /locus_tag="ACHDPO_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFN3368029.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            9522..9962
                     /locus_tag="ACHDPO_000366"
     CDS             9522..9962
                     /locus_tag="ACHDPO_000366"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFN3368030.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            10012..10206
                     /locus_tag="ACHDPO_000367"
     CDS             10012..10206
                     /locus_tag="ACHDPO_000367"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368031.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            10342..11019
                     /locus_tag="ACHDPO_000368"
     CDS             10342..11019
                     /locus_tag="ACHDPO_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3368032.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(11427..12116)
                     /locus_tag="ACHDPO_000369"
     CDS             complement(11427..12116)
                     /locus_tag="ACHDPO_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368033.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(12091..14220)
                     /locus_tag="ACHDPO_000370"
     CDS             complement(12091..14220)
                     /locus_tag="ACHDPO_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFN3368034.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(14268..15605)
                     /locus_tag="ACHDPO_000371"
     CDS             complement(14268..15605)
                     /locus_tag="ACHDPO_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFN3368035.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(15857..16216)
                     /gene="rplT"
                     /locus_tag="ACHDPO_000372"
     CDS             complement(15857..16216)
                     /gene="rplT"
                     /locus_tag="ACHDPO_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFN3368036.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(16269..16469)
                     /gene="rpmI"
                     /locus_tag="ACHDPO_000373"
     CDS             complement(16269..16469)
                     /gene="rpmI"
                     /locus_tag="ACHDPO_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFN3368037.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(16541..17065)
                     /gene="infC"
                     /locus_tag="ACHDPO_000374"
     CDS             complement(16541..17065)
                     /gene="infC"
                     /locus_tag="ACHDPO_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFN3368038.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(17109..17234)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            17385..18017
                     /locus_tag="ACHDPO_000375"
     CDS             17385..18017
                     /locus_tag="ACHDPO_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFN3368039.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(18019..18924)
                     /locus_tag="ACHDPO_000376"
     CDS             complement(18019..18924)
                     /locus_tag="ACHDPO_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFN3368040.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(19009..19668)
                     /locus_tag="ACHDPO_000377"
     CDS             complement(19009..19668)
                     /locus_tag="ACHDPO_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFN3368041.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            19984..20928
                     /gene="mvk"
                     /locus_tag="ACHDPO_000378"
     CDS             19984..20928
                     /gene="mvk"
                     /locus_tag="ACHDPO_000378"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFN3368042.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            20921..21898
                     /gene="mvaD"
                     /locus_tag="ACHDPO_000379"
     CDS             20921..21898
                     /gene="mvaD"
                     /locus_tag="ACHDPO_000379"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFN3368043.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            21911..22996
                     /locus_tag="ACHDPO_000380"
     CDS             21911..22996
                     /locus_tag="ACHDPO_000380"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFN3368044.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            22993..24057
                     /gene="fni"
                     /locus_tag="ACHDPO_000381"
     CDS             22993..24057
                     /gene="fni"
                     /locus_tag="ACHDPO_000381"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFN3368045.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(24306..25109)
                     /locus_tag="ACHDPO_000382"
     CDS             complement(24306..25109)
                     /locus_tag="ACHDPO_000382"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFN3368046.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25129..25971)
                     /gene="kduI"
                     /locus_tag="ACHDPO_000383"
     CDS             complement(25129..25971)
                     /gene="kduI"
                     /locus_tag="ACHDPO_000383"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFN3368047.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(25987..26994)
                     /locus_tag="ACHDPO_000384"
     CDS             complement(25987..26994)
                     /locus_tag="ACHDPO_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFN3368048.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(27001..27645)
                     /locus_tag="ACHDPO_000385"
     CDS             complement(27001..27645)
                     /locus_tag="ACHDPO_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFN3368049.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(27745..28503)
                     /locus_tag="ACHDPO_000386"
     CDS             complement(27745..28503)
                     /locus_tag="ACHDPO_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFN3368050.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(28630..29781)
                     /gene="fucO"
                     /locus_tag="ACHDPO_000387"
     CDS             complement(28630..29781)
                     /gene="fucO"
                     /locus_tag="ACHDPO_000387"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFN3368051.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(29863..30174)
                     /gene="rhaM"
                     /locus_tag="ACHDPO_000388"
     CDS             complement(29863..30174)
                     /gene="rhaM"
                     /locus_tag="ACHDPO_000388"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFN3368052.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(30176..31021)
                     /gene="rhaD"
                     /locus_tag="ACHDPO_000389"
     CDS             complement(30176..31021)
                     /gene="rhaD"
                     /locus_tag="ACHDPO_000389"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFN3368053.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(31035..32291)
                     /gene="rhaA"
                     /locus_tag="ACHDPO_000390"
     CDS             complement(31035..32291)
                     /gene="rhaA"
                     /locus_tag="ACHDPO_000390"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFN3368054.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(32288..33748)
                     /gene="rhaB"
                     /locus_tag="ACHDPO_000391"
     CDS             complement(32288..33748)
                     /gene="rhaB"
                     /locus_tag="ACHDPO_000391"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFN3368055.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            33901..34770
                     /locus_tag="ACHDPO_000392"
     CDS             33901..34770
                     /locus_tag="ACHDPO_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFN3368056.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(34896..35795)
                     /locus_tag="ACHDPO_000393"
     CDS             complement(34896..35795)
                     /locus_tag="ACHDPO_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3368057.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(35960..36784)
                     /locus_tag="ACHDPO_000394"
     CDS             complement(35960..36784)
                     /locus_tag="ACHDPO_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFN3368058.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(36795..38090)
                     /locus_tag="ACHDPO_000395"
     CDS             complement(36795..38090)
                     /locus_tag="ACHDPO_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFN3368059.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(38106..38585)
                     /locus_tag="ACHDPO_000396"
     CDS             complement(38106..38585)
                     /locus_tag="ACHDPO_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFN3368060.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(38591..39619)
                     /locus_tag="ACHDPO_000397"
     CDS             complement(38591..39619)
                     /locus_tag="ACHDPO_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFN3368061.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(39636..40742)
                     /locus_tag="ACHDPO_000398"
     CDS             complement(39636..40742)
                     /locus_tag="ACHDPO_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFN3368062.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(40971..43568)
                     /gene="adhE"
                     /locus_tag="ACHDPO_000399"
                     /gene_synonym="adhC"
     CDS             complement(40971..43568)
                     /gene="adhE"
                     /locus_tag="ACHDPO_000399"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFN3368063.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(43873..44253)
                     /gene="yajC"
                     /locus_tag="ACHDPO_000400"
     CDS             complement(43873..44253)
                     /gene="yajC"
                     /locus_tag="ACHDPO_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFN3368064.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(44350..45495)
                     /gene="tgt"
                     /locus_tag="ACHDPO_000401"
     CDS             complement(44350..45495)
                     /gene="tgt"
                     /locus_tag="ACHDPO_000401"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFN3368065.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            45713..46411
                     /locus_tag="ACHDPO_000402"
     CDS             45713..46411
                     /locus_tag="ACHDPO_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFN3368066.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(46579..49218)
                     /locus_tag="ACHDPO_000403"
     CDS             complement(46579..49218)
                     /locus_tag="ACHDPO_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFN3368067.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(49837..50868)
                     /gene="queA"
                     /locus_tag="ACHDPO_000404"
     CDS             complement(49837..50868)
                     /gene="queA"
                     /locus_tag="ACHDPO_000404"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFN3368068.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            51061..52236
                     /locus_tag="ACHDPO_000405"
     CDS             51061..52236
                     /locus_tag="ACHDPO_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HFN3368069.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            52240..52881
                     /locus_tag="ACHDPO_000406"
     CDS             52240..52881
                     /locus_tag="ACHDPO_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368070.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            52878..53795
                     /locus_tag="ACHDPO_000407"
     CDS             52878..53795
                     /locus_tag="ACHDPO_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFN3368071.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            53792..54463
                     /locus_tag="ACHDPO_000408"
     CDS             53792..54463
                     /locus_tag="ACHDPO_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368072.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(55004..55492)
                     /locus_tag="ACHDPO_000409"
     CDS             complement(55004..55492)
                     /locus_tag="ACHDPO_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFN3368073.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(55693..55959)
                     /locus_tag="ACHDPO_000410"
     CDS             complement(55693..55959)
                     /locus_tag="ACHDPO_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFN3368074.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(55959..56222)
                     /locus_tag="ACHDPO_000411"
     CDS             complement(55959..56222)
                     /locus_tag="ACHDPO_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFN3368075.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            56743..56883
                     /locus_tag="ACHDPO_000412"
                     /pseudo
     CDS             56743..56883
                     /locus_tag="ACHDPO_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(57025..58848)
                     /locus_tag="ACHDPO_000413"
     CDS             complement(57025..58848)
                     /locus_tag="ACHDPO_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFN3368076.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(59446..62151)
                     /locus_tag="ACHDPO_000414"
     CDS             complement(59446..62151)
                     /locus_tag="ACHDPO_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFN3368077.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(62457..63404)
                     /locus_tag="ACHDPO_000415"
     CDS             complement(62457..63404)
                     /locus_tag="ACHDPO_000415"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFN3368078.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            63594..63863
                     /gene="rpsN"
                     /locus_tag="ACHDPO_000416"
     CDS             63594..63863
                     /gene="rpsN"
                     /locus_tag="ACHDPO_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFN3368079.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(64039..64401)
                     /locus_tag="ACHDPO_000417"
     CDS             complement(64039..64401)
                     /locus_tag="ACHDPO_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFN3368080.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(64412..65533)
                     /gene="alr"
                     /locus_tag="ACHDPO_000418"
     CDS             complement(64412..65533)
                     /gene="alr"
                     /locus_tag="ACHDPO_000418"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFN3368081.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(65549..65899)
                     /gene="acpS"
                     /locus_tag="ACHDPO_000419"
     CDS             complement(65549..65899)
                     /gene="acpS"
                     /locus_tag="ACHDPO_000419"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFN3368082.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(66029..67540)
                     /locus_tag="ACHDPO_000420"
     CDS             complement(66029..67540)
                     /locus_tag="ACHDPO_000420"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFN3368083.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(67862..69214)
                     /gene="murF"
                     /locus_tag="ACHDPO_000421"
     CDS             complement(67862..69214)
                     /gene="murF"
                     /locus_tag="ACHDPO_000421"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFN3368084.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(69367..70443)
                     /locus_tag="ACHDPO_000422"
     CDS             complement(69367..70443)
                     /locus_tag="ACHDPO_000422"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFN3368085.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            70639..72384
                     /locus_tag="ACHDPO_000423"
     CDS             70639..72384
                     /locus_tag="ACHDPO_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFN3368086.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(72664..73101)
                     /locus_tag="ACHDPO_000424"
     CDS             complement(72664..73101)
                     /locus_tag="ACHDPO_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFN3368087.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(73085..74458)
                     /locus_tag="ACHDPO_000425"
     CDS             complement(73085..74458)
                     /locus_tag="ACHDPO_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368088.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(74780..75268)
                     /locus_tag="ACHDPO_000426"
     CDS             complement(74780..75268)
                     /locus_tag="ACHDPO_000426"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368089.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(75290..75892)
                     /locus_tag="ACHDPO_000427"
     CDS             complement(75290..75892)
                     /locus_tag="ACHDPO_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFN3368090.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        21761 a        16239 c        13903 g        24032 t
ORIGIN      
        1 tatcatccat atcctctaat agatttttta aacacttttt ttcatctatc atgttttttc
       61 tccttgccat tattctaact aaaattttac gtatttgttt ctatgtctac attatctttt
      121 taacagtatc tatttttctt ttgcaactta cttggctacc aaagcaaata aaaaagttat
      181 ttataaattt ctccctacca ctacctattg ctattattta aaatagggat aattttttct
      241 cttaaaaaat atcattattt gtggtatgga gcccccgcat tgatccggaa ggcacggtag
      301 atttgctcga caaggatcag acgcatcaat tgatgtggat acgtcatttt tccaaaagag
      361 atctgagcat tgcttctttt catgacggct tcgctgagtc ctaaagagcc gccgataaca
      421 aaaacaaggt ggctttttcc ttggatacct aattggtcga tttgtttagc aaaagattca
      481 cttgtaggat ttttcccttc aattgctaag gcatagacgt attcttgttc tttgattttc
      541 gctaagatcc gttccccttc tttttctttt acttgtctca tttgcgcttc gcttaaattc
      601 tccggggctt tttcgtcagg aacttcgatc aattcgattt ttgcataggc attcagccgt
      661 ttgacatact cattgatacc ttggatcagg tatttttctt ttaattttcc tactgagata
      721 attttgatat tcatgttttc tctcctttgg tcttcatgct cactttgttt attataatca
      781 attttttcgt ctatatgttt attttggcta tttttgttaa aaagatttcc ccaacagtta
      841 tgcacaacat ccacaggttt atccacagaa aacagtgtta ttttacctta tttcatcaca
      901 ttcattaggc aaacatacgt tttataagaa tttatccact ttatacacag gctgtggata
      961 tgttttatcc cttatttttc caatcctatc cgcgtagttt tacacagtat ctgtggaaaa
     1021 agaaaatcaa atattttcat ctgaaaacaa tgatttttcc taaagttttt cataaaaagt
     1081 tcacagtctc aaagtagact aaagtcaaca aataagacta tactaacagt agataaatga
     1141 atgtaattgg aggaggaaca catggataga aaaaatgtga caccaaagat gaaaaaaagt
     1201 aaaaataata gcctctggcg taagttaggt ctggggcttg ttggagggat cgttggagga
     1261 ctactgacag ctggcatttt ttatgcagcg atgggcactg gcaacaatag ttctactgct
     1321 acaagcggca atcagaattc tgccggtgaa acagttgtgg aaaatgtcaa agtcaatgta
     1381 gattctgata tcaccaaagc ggtagataaa gttcaagacg ctgtcgtttc tgttatcaac
     1441 ttacaaagtc aaaaccaatc aagcggtttt ggcggactat tcgggcagca agaagaaagt
     1501 agcagctcag atgatagtaa tttggaagct tatagtgaag gaagcggcgt gatctacaaa
     1561 aaagacggga atactgctta tgtagtcacg aataatcacg tagtagatgg ccagcaaggt
     1621 cttgaagtct tgatgaaaga cggtacgaag gtaaaagctg aattagttgg aacagatgct
     1681 tattcagatt tagcggtgtt gaagatcaat tcagacaaag tcgaaacagt tgcctctttt
     1741 ggtgactcaa gtgctctgaa ggttggtgag cctgcgattg cgattggttc cccactagga
     1801 tctgaatatg caaattctgt cacttcagga atcatttctt ccttgaaccg acaagtgaca
     1861 agtacgaatg aatcgaacga aacagtcaat atcaatgcga tccaaacaga tgcagcaatc
     1921 aaccctggaa attctggtgg tcctttagtt aatatcgaag gacaagttat cggtatcaac
     1981 tcaagtaaga tcgcaagtac ttctgaatct acttctaatg taagcgtaga aggaatggga
     2041 tttgctattc caagtaacga tgtagtgaat atcatcaatc aactggaaaa agacggaaaa
     2101 gtgacacgtc cagctctagg tatcacaatg gtcgacttat ctgccgtttc tactcagcaa
     2161 caagaacaaa tcttgaagat tccttcatct gtaactaacg gtgtcatcgt gacaaatgtc
     2221 caaacagcta caccggctga aaaagctgga ttgaaacaat acgacgtcat tactaagatc
     2281 gatgacaaag aagtttcttc tggtgtagaa cttcaatctg ctttgtataa gaaaaaagtg
     2341 ggagattctg tcaaaatcac ttactatgaa ggctcgaaag aaaaaacaac tactgttgaa
     2401 ttgacgatcg atcaatcggc attaaaacaa aatcaaaata gtgaaaatta ataaaaaaga
     2461 ggttgtgaca aagacttgtc acaacctctt tattttggaa atgcttctcc gactacggca
     2521 tcctcaggca atactaagat tccttttttt gctggagcat ttggcaaatg caattcacga
     2581 gcggaacaga tcattccata gctatctacc cctcgcaaag ttcctggcca gatcatcatt
     2641 ccatctggca tcatagctcc tggttttgca acgacaactt tttgtccagc ttcgatattg
     2701 ggtgcaccgc aaacgatttg caatactgta ccattgtcta cttctgtctc agtaatcgat
     2761 aaatggtcag aatcaggatg tgggacgcat gtttttacgt acccgacaac gatcttcggt
     2821 tcatgatcag cttcaagctg ttcttcgaat cctgcttctt tgatcaatcg attcaatttc
     2881 gctaattcct catctgttaa gcttacttgg ccgttccctt cgattgttag atgatcggag
     2941 atatggaaaa agttccaagc aacaacttga ccttgttcat ctttgatccg agcaacattc
     3001 catttgcgtt caacagtgtt ttctgttcct ttatcgtcgg ctataataac catcaaggtg
     3061 tctccgacgt gtgctttgtt ataagcaaaa atcatgttct ttcctccatt atcctttgct
     3121 gagatttatc ttaacaaaaa attgcattca ctgcatgaaa tttttttcat gctttatttc
     3181 cgaagaagcc tcttctggaa caccatttat tcgtaacaag ggactgtgac aagacttttg
     3241 tcacagtccc tttactgttt tagttaattg attaaaaagg tcgtacaagt tccacttgct
     3301 taattacttg gctgttcttc ttcgtcagaa acgatcaaga catcacaagg tgaatgacgt
     3361 atcacgtagc tggctacact tcctgtcata aagcgttcga ctgcatttag acctgactgc
     3421 ccaaccatga ttagatcgat ctcatatttt tttggcaatt tgactgccat ggattcacga
     3481 acagaaccat atgcaataat tccttctata tttgtgtaat caacagattt cccatattct
     3541 ttacattctt cgatcatttc cttggctgtt tcagtttgct gatcgactag attttgatca
     3601 ataggtgcat agcccataaa gttataaaat tgctgatcga ttacgtttgc tacatatact
     3661 ttcccattat tacggcgagc cacttctacc gcttttttga aagcagcaag tgcttgttca
     3721 ctaccgtcga tacctactaa aatattctta tattcttgat tcatcttgac ccctcctaac
     3781 agatgtcagc cttttgttac actttctagg aacgattcga tttcctgttt tgttttacga
     3841 tctttattca ctagacgacc taattctttt ccgtcttgga tcacgacaaa acttgggata
     3901 ccaaaaatgt tccattcagc ggctacatct atgtacttgt cacggtctac ttcaataaat
     3961 tgccaatcag aaaagtcatt ttcaatttca ggcatttgcg gtttgataaa acggcagtct
     4021 ccgcaccagc cggcagtaaa gaaaaataca ctctttccag tttctacgta gcctgctaat
     4081 tcttctaaac tatttgggat aatcattctt tgtcctctac tttctgttta tgtatttttc
     4141 aattaaatta tacacctttc tttcgaacta acaaacattg atcctctttt tataaaaaaa
     4201 atctggcaaa aagcaatctt ttgccagatt ttatagtttc actatcgcat tattttccgt
     4261 atacgatcgt atttactgtt gatttatcca aacctttcag tgtttgaatc aacatttctc
     4321 gtgcagcttc aaaatcgcga atactgaaca tcgtttgatg cgtatggata taacgtccca
     4381 ctacgccaat cactgtactt gggattcctt cgttttgtgt atgagcagca cctgcatctg
     4441 taccgccttt tgaaacaaag tattgataag ggatattgtt tgtttcagcg atatccagca
     4501 agtactcgcg caaacgagga agcatgatca aacctggatc ttggatacgc atcaatgtac
     4561 cttctcctaa atgtccgaat gtgccatttt tcgtcactgt atcatctgct gcagagcagt
     4621 ctactgcaaa gaacagatct ggcttgaatt tattgacaga agctttagaa ccacgcaagc
     4681 ctacttcttc ctggacattc gcgcctgcaa tcaatgtatg acctaatgtt tcattttgca
     4741 acgcttctaa agcttctaat accattgtac agccatagcg gttgtcccat gatttactga
     4801 taatattctt tccgttggct gttttgatcg tttcagcgta aggaacgatt gtgtctcctg
     4861 gaaggacacc gtaactcatt gcctcttctc ttgattcaaa cccagcatcg aacaaaatat
     4921 cggttacttc tactgatttt tgtccgcttg ttcctcgcaa taaatgtggg ggaacggaag
     4981 aagaaataca tggataattc ttaccagtag aggttttaag tgtaaaacgc tgagcagaaa
     5041 caacgtaagg attccagccg cctagaggta cgactttaaa aagcccgttt tcttggattt
     5101 gtgtcagcat gaatccgact tcatccatat gtgctgcgac cattacacgg ggtgcatccg
     5161 cttcttcatg atggcgcaga ccaaaaatgc cgcccaaacc atctaactgt aactcatcta
     5221 ccagcggttc catatgactt tccatataag cgcgaacatc ttgttcaaaa ccgcttgttc
     5281 cttgtaattc tgttaactct ttgattcgtt gaaatgtttt ttcttccata tgctattcgt
     5341 ctaaatttca gactaaactc ctctcagact tatattgatc tgcggataaa atatgatttt
     5401 ttctgcagac cgatcgtatt tattatagct tattttttct ggtagcggtt atttatttca
     5461 aagaaaatat gagagtgtgg taaaataagc acaaggagta acaagtgaga agaaggaggt
     5521 atgtccacat gtatgaagaa agcgaactaa gctattttaa aggcgggtta gcagttggaa
     5581 tcggtctagg attattgagc ggggtagctt caacgatttg gtatcatcgc aaaaaagtat
     5641 tgtcagcaga ccaagtactt gaaaatatca agtcatcttt tctaaaagaa ggtgcaatcg
     5701 aaggttcttg gatctctttt gaaaaggaac ctattaggaa attcgccgtt cggtcgagtg
     5761 cttatcgggg aggtctttct cgaatagaag atggcgaaac tgtttattat gaatttttag
     5821 cagatgctca tacaggaacc gtattagaaa tttcaagaaa aaaaggtgca acagattaat
     5881 acgtcaaaaa agtgagagaa cgaatacgca cccactattc aaaagagagg tatcatgtcc
     5941 ttcttttgta gtgggtggtt ttttagatag agctttccaa acatatattc cagtattttc
     6001 tttttaaata aatgatattt agcgggaaaa actagcattt cctttgatta tgaggtattt
     6061 ttaatttagc ttttgttttc tatagttaag gagagtgaaa aatggaacaa caagaaaaaa
     6121 ttgctgttct gattccttgt tacaatgagg aagcaacaat ttcaacagtc attgcagact
     6181 ttaaacgaga attaccagaa gcagatattt atgtctatga taataattcg accgatcgaa
     6241 catacgaatt ggccgttcaa ggtggagcaa tcgtaaaaaa agaacctcgt caaggaaaag
     6301 gaaatgtgat ccgccaaatg ttctttgata tcgatgccga ctattattta atggtagatg
     6361 gcgatgatac ttatcctgca gaagctgtac atggtttgct cgagaaatta cgttctggtg
     6421 aagcagatat ggtcattggt gatcgcctat caaatggaac ctactttgat gagaataaga
     6481 gacctttcca cgattttgga aataaccttg ttagaaatac aattactaga atgtataaaa
     6541 caaaaattct tgatgtcatg accggctatc gaggattcaa tcgtatcttt gtcaaaagtt
     6601 ttcctattat gagttctggt tttcaaatcg aaacggaatt gacgatccat gctttagata
     6661 aaaaattcaa gttcgttgaa atcccaatcg attatcgtga tcgtcctgaa ggcagcgaat
     6721 caaaattgaa tacattctct gacggattca aagtgatcat gatgattatt aaaatgttta
     6781 aagattataa gcctttgctt ttctttggga tttggaccat cttcttcttt ttatttggat
     6841 tggtcacggg gattcctgtg attcgcgaat atatgctgac aagctttatt acacgcatcc
     6901 cttctgcgat tttaagtact ggattgatga ctttagcact tctttcatta gtaacagggt
     6961 tgattttgga tacagtcgtc acgaacgcta agaaagaata tgaattgaat ctatatcatg
     7021 tttatcatga ataccacagt agaaagtaaa aaaaggatca agactgcaaa aataatttgc
     7081 aattcttgat cctcttttta attaattatt tcgccaaacg atagatggca tctgcataga
     7141 ttgctgttgc tctgaacaag tcatcaagac tcataaattc gtttgcttga tgcattgtat
     7201 cagtatatcc tgggaacatc gctccataag caacgccacg tttcaacaaa cgtccgtaag
     7261 ttccgccacc gatgatttgt tcgtagcctt tttctccagt gtggtcttca tagacttgca
     7321 ataatgtagc caccaatgga tcatccattg gtacgtaatg tggttccatt acgcgagcac
     7381 ctcgagtaac tgttgcgcct tcttgcccca ctgtttgttc gatgtcactt tgcaatccgt
     7441 ctactgttac accttttgga aaacggaaat tcatattgat gaagttcgct tcctctgtac
     7501 cattttcttc aaaagcaaat agtccagcat tcattgtcaa tttgcccatt ttttcatctt
     7561 cataagcgac tcctagtttt tctccataaa aatcttcatg gacataagca gctgctacat
     7621 ggataaattg tttagcagat cctaggaatt catagttatc taagaacaat gccaagaaag
     7681 aacctgcatt gataccagat tgtgggcttg caccatgtgc gcctttacca actaattcga
     7741 tttttacata cgtattgtcc gcttcaatcg ttccgcttac tggatttgct tcgatgaatt
     7801 ggtaaaatgc ttcttccatc gcgatagctg catctgcact tggtacttga agtgctgcag
     7861 ttgctgttcc tggcaccata ttttcgcgaa gtccggaaac aaaagatttc aagacataat
     7921 ctcctgcatt gtcgcctttg aagcgtaaag ctaaagaaac atttcctttt tcaccattga
     7981 tgattgggaa ttcagcatct ggtgagaaac caaaatctgg ttcttcttca tgttcgaaat
     8041 aataagccat atcgccccag ccgctttctt catcgctgcc gactacgaag cgaacttttt
     8101 ttgatagttt caagtcaagt tctttaatga tcttcatcgc atagtaagct gccatacttg
     8161 gacctttgtc atcgcttgat ccgcgtgcaa agatctttcc atccttgatt actggttcat
     8221 aaggatctgt gtcccagcca tctcctgcag gaacgacatc catgtgtcca aatatcccta
     8281 gcgtttcgtc tccttcgcca agatcaatat gccctgcata gttatcgaca ttttttactt
     8341 taaatccatc acgttcgcca taagctaaca tatgtttcaa tgcgtcgcga ggtccaggtc
     8401 caaatggtgc atctggtgtt acttttgagt catcgcgctc gctgttgaca cgtaaaagat
     8461 ttttcaagtc ttcaagcaag tcttctttac gtgcttctac ttctttttgc caatcaattg
     8521 tcataaagtt aatcctccac ttatttaagt cttcgtgttc atgataccac aaattacaga
     8581 aaaaaatagt tcaaaaaatc tgacaattcc ttttcttatc tgtttttctc taaaaaaaat
     8641 atacgctata atgagtaaaa ggaggttttt agatgctgat aaacgaacaa ctagtgaaaa
     8701 gagtcatcac acctcgtcca aaaatttcac ataaaggaac atttggacgt atcgttttga
     8761 ttggcggcaa tgaacaatat ggcggagcaa tcattatgag tgctttagct gccgtacaca
     8821 gcggagcggg tctcacgact gtagtaactg atgaaaaaaa tcggagtgct cttcacagtc
     8881 atctgccaga agcaatgatt gtagtttgga cggatactga ccagtttctt tccgtaataa
     8941 agcaagcaga tgtactcttg attggtcccg gattgggtac ttcttctaag agtttggaac
     9001 gtttcaaaca agtactagaa aaccaatcaa aagaacaatg gctggtgatt gatggctctg
     9061 ctttaagttt acttgctgct aatcatcttt tgctacccta tcccgaacaa actgtactta
     9121 cacctcatca aatggagtgg caacggttga gttctctacc gatacaagaa caacgggata
     9181 aagaaaacaa aaagaagcaa caggaaatcg gtgctgtgct cgttttgaaa agtcatgaga
     9241 caaaaattta tggtcaccag cacttctaca ccaatccttt aggttctgct gctatggcaa
     9301 cgggcggcat gggtgacact ttagctggga tgatcacagg atttttagcc cagtttcctc
     9361 aaaatgacca aacgattgca gcagctattt atcttcatag tttcattgga gaccagctgg
     9421 caaaagaaca atatattgtt ttgccgacac aaatcagcga agcacttccg aaatggatga
     9481 attatttttg taaaaaatca atggaaaacg aggcatgagt catggagaaa tttacaggtt
     9541 atgtgcgaga acctttttat tatgaaacag atcaaatggg gattattcat cacagcaatt
     9601 atatccgctg gtttgaagag gctcgggtag ccttattggt acatctaggg tttccctata
     9661 aaaaaatcga agaatctggg atcatcatcc ccgttctgga agtaaattgc agctataaag
     9721 aaatgatcca ttacggagaa aaagtgagca tccatccaac tatccaaaag tatacgggga
     9781 cacggttgga ttttagctac gaaattgtgg gaactgaaga caaaaaatta aaaactactg
     9841 gcagtagtaa acactgtttt ttactttctg attcgcaacg attagtgaag ctgagcaaag
     9901 tcaatccgga gttagatcag ttattccaag cgtacgcttc tttggatgat gtaaattctt
     9961 aataaagacc gtctaagcat ttttcttgta ttgtgtcgag tagttcgtat aatgaaaaga
    10021 aaaaagcagg tgatccccat gtatgtcgtt aaagtaatgc acggttacat cgataaaact
    10081 ggctgtcgca ctcgggaaaa aaacttagac aatctgctca ttttcaaaga caaaaaagaa
    10141 tccgaagctt ttgctaaaag aatcggcggt cgtgtcaaac cgatccaaga ggtacgacca
    10201 gattgattca atatttttct tttcgaggct ctaataggca tgcctatcag ggcttttttt
    10261 gcagactgtg tttttatgcc cacacgattt gtaagcgatt tatgttataa tagattatat
    10321 ctgcatagaa aggaaggtta aatggttatc aataatttgc aacagcaagc ttatgaatct
    10381 atacgtaaac aaatcattta ttccgagtta gcacctggaa gtaaaatctc cgataaagtg
    10441 ttagaagaac aactagctat cgggcgtaca ccgattcgag aagcactgat ccaactgcgc
    10501 aatcaagagc ttgtaaaaac cattccacag tccggcactt atgtttcaaa aatcgatatc
    10561 cgatctgctt cattagcccg ttatacgcgg gaaaagttgg aaaaaccgat cctgcaagaa
    10621 tgcagtgcga aaatgaccaa gcaagatcaa gctaaactag aaaaaatact agaacaaacc
    10681 gatcaggcag taatcgctca aaataaaaaa gctttttttg atttggatac tgattttcac
    10741 cgaacttgtt atgaaattgc tggaaaacga gaaatttggg attggctaga aagttatagt
    10801 acgcgtttca gatggttacg tttgacgatt tcagaattag actggggtcg agtattagat
    10861 gaacatcaga caatgcttca atcaatgatt gatcataact ttgatgaagt cggatttctt
    10921 tgcacgatgc atttacatat gattatcgag gagcaagaat acgtgattca taattacccc
    10981 gattattttg aagatattca ggacagaccc atcaaataag aggttttgga atcagcgttt
    11041 tgacctgagt attagagaaa gaaacggcaa aatagttcct catattttgc cgtttttttt
    11101 gagctaatac cgagggtcag ctgattgcac accgtttatt gagaggttgt gaaaaagctg
    11161 ccctgcatca agtaataaga acagccaagt aaaaatagct tcttatgttt ttaacttggc
    11221 tggacttatt accgcagatg caagcttttg aacaccgttt tccaagaggt cgtgagcctg
    11281 ccgttcatct ccgagtcaca aggaacaatt tcaaaaaaca gcttctcatg tttgttgaat
    11341 attttgactt gtgaccgagg agttgacagg agaacatcgt ttattcggaa aaaaaggact
    11401 gtgacacgac ttttgtcaca gtctctttat ttgtaatcta aatcatactc cgtacatctt
    11461 ttttctattt tttttatttc ttctaagatc ccttggctac gaatttcatt atatggccaa
    11521 agtaagactg cctctaatac ataaggcgaa aaatcgcttt gattcatctc ttttgaaaaa
    11581 ctcatcgctg ctatctcgct caatgcacga atgtttgatt gatgtgtata aaaaggcaac
    11641 cgccacagca caattttttc gctttgcgta taaattccct taacagaagc ttcgatgtgg
    11701 tgaaatagtt catgtccaat aatcaaagct tgcgctgttt ctttagagat cgaagctagt
    11761 cctgaacatt ttaatttttc taacggctcc gtcatcaatc gaatcccttc atcttctgca
    11821 taagttgcaa aagtgattcg ttcgtttatt tgctctgatt cacaggaaac gattggaaca
    11881 gccatttgtt cacaaatttc tcctacatcg gcaaaagggt actttttttt gatgctacat
    11941 gccgtttcga taccacaatc gattgattgt tgtataagaa ttttctgctt ggacaaagga
    12001 atctttttcc aaaataaatc tcgccgaaac tggtagaatc cccaaatttc ttcggggatc
    12061 tgttgtaatt cgtttagtaa ctcttctaac ttatgtttgt ttgatatttc cggcaacgac
    12121 gatcacttct tcctccggtt ccatagtaga tacttccaga tccatcaaaa gctgtagttg
    12181 ttccagatcc gtcgctgtaa aatcagagac tcttgctcct aagcagagat aaaattctgg
    12241 tcgggcaatc aattcagttt gataaactgc catatcttcc caaagttgtt cgacagctgt
    12301 catataattg gctgcagttg ttttcataca tgaagcatgt ccacgttgga ccttgataaa
    12361 tcctttttga tcgatgatcc gaagacttcc agcatttttt gaacgattct gttcgccgca
    12421 tacataaaag aaaggtgtat tttccaataa gcaaacttca tttttattta atcgcatatc
    12481 ctctgcagca agctctagtg cttcttctgt tgtgatctcc ttggttagat cggttgcttt
    12541 cacttccgta gaaccagtag cgatagccgt tacttttgaa gtctgtggat cgatttctac
    12601 gtggacttcg atcgattctg gtgtagcgcc tgattcaatc gctttattca tcgcttcatt
    12661 tttcaacgat cgtatatctt ctttacttgg cgaagggatg atacgttcta caacatctcg
    12721 gaccattgca agtgctacac caatagaaga aatcacttcg gcgttttcag gaatcgaata
    12781 tttcacaccc attttattac taaagtaagt aatcaatgag gcagcgccgc cccctacacc
    12841 tacaagagaa atctgatctt tctccaagtg atacttgtct gccaattcta aaatcaccgg
    12901 ttcaatctta gcataggatt tttccatgat ctgttctgcg atgtcttcaa ccgtcgtatg
    12961 acaataatca gctaatgctt ggatggcttt tcgtgcagat gggacatttc cataagaaaa
    13021 atgttcttct tgcactaatc caaggacatt ggctgcacat gtatttgtaa tagtcacttc
    13081 ttctccgtct tccatcacta ccttgacgta atcagcaggg tctccttctt taggagagaa
    13141 aaattcaacc ttaggacctt tgattttttc tgtctccgta aatactgcat aatctagacc
    13201 ggcaatatgt gcagaacgtg gaccgacatc gatgattcct gactgattag cccgtaccat
    13261 cgaaccgcct gccacaccta gaacccgaac atctaatgaa gagatatatg ttgggtggcc
    13321 acctacaatt gaataatcga ttgctggacg tccattttta atgaccccga tattggttgt
    13381 tgttccgcct acttcaaaat aaacaccatt agacgctctc aagtacatca aagagcccat
    13441 gactgatgct gctggaccgg aaagcatggt taaaacaggt cgttttttca tttcattgat
    13501 ttccattact ccgccgtctc cgcgcataat catcaaagaa acattgaccc ctgcttctcg
    13561 tacggaatct tctgtagagg ttgccgtatc tagcattttt ggtaaaatag atgcattgat
    13621 tgctgctgtc cgagttcttc ttgtcaatcc atataatttt gtgatgtcag aagccatcgt
    13681 tgtagggatc gattttaccg atgctgcttc ataaacaact cgttctggtt ccccattatc
    13741 tactccaaat gccatagaag aaaccaagac ctccgctctt tctctttcta aagaagaaat
    13801 cgtttctgaa acacggtcta catttaagtg tttgacaggt aagaatgcat tgacaatctc
    13861 tatttttttc ttattcccta aatcgatatc gttcaatcta gtttgtcgtt ttgctaaaaa
    13921 accttctaat ccaccttttg ccatcccgat tacgccgact tttgctacgt ctccttcaat
    13981 cagtgcatta gtcgcttgtg tggtagaatg tgcaacaaac acaacatctt ctggactgat
    14041 attattttcc agcaaacaat tttgaaaaga ctgaacgaca cctgcggcta ctccacggac
    14101 atcatcgtgg gttgttttca ctgaagattt tccgatgatt tcgtgcgtcg cattatcgat
    14161 tgcgactgct ttcgtatgtg taccgccaac atcaattccc attcgcacaa aacgtttcat
    14221 tttcttttcc tccattcatc taatcgtttt tatcgacgtt ttgtttacta ggcgttcccg
    14281 tacaataaga acgtgatcag gcataagatc gctccgatga tccaaccagt tgggatggat
    14341 ttcttcatat attctcgaga agttactttt gtataaccta atccccaagc aacccaagat
    14401 tgtgtaatat ctaaatgctg aggagcaatc gttgtgattg caaataacgg gaacaaaaag
    14461 gctggcgaca tcgttggatt aacagctaat acgacagcta aaatagctga gcctgaaccg
    14521 actagattca ttggaccgcg gaaaaatcct agtggtgtca atatagcaaa tacgattgcc
    14581 aagactaatg gtgattgcgg tatccaatct ccaaaaatag ctgaaaaata aggagaagca
    14641 tacgcagctg aattattgaa catcgctaag gtcatcaaga aaccaaccat tggcgcaaca
    14701 tctactgcgc catctgtaaa taatttcgca aactgacgac agatttcttt ataacctccg
    14761 cgcaattttc cagtaaacag caatgcccag atacctgcta gaataaaacc taagatgatt
    14821 ggaagatcta aaagaacgac ccctaaaact ggtaataata cggctaacca tgagatcatt
    14881 ggtgcgtcgc caccttcagc tggtacgttt gctgccattg catagcgttt ctttttgttc
    14941 attgatatat tagcgaccgt tagtaccaca actaagctta caatcatccc aatcatacca
    15001 atttggaaat agtcattata agtatagctt tcagccgctg gattgaaacc agcataaatc
    15061 gtttgatatt gtttgaaatt gacgatatta gcaaagattc cagccataat cgagcccata
    15121 aatgagaaca gtgcaaccgg tactgaaata cctaatgaca tcaagattgg caacacaata
    15181 actgcaatag aaatcactgg tccgattcct gtcatcgaca tgaatataac agcggttaca
    15241 atacatagta agctcatcgt gattcttggc ttgtcccctc caagttcaac tacctttcga
    15301 atcagggtag ctgcgattcc gctatctact agaacacgcc cgaaaaaggc accaaagaag
    15361 acatttacca agatcgattt ggcgtactca gctggccccg tcgtatagat atgcgtcaac
    15421 acatcaatta ctccttgccc ttccatcgcc gggtttggtg aaaacgtgtt tccgactagc
    15481 gctaatccca tccatacagt agccatgatg gcaaagccga ccatcaagtt gtagcctttt
    15541 acacagtacc agaccatgaa aaagaatgag ataactaaca aaataccaat aataatatca
    15601 ctcatgttat tcctccgtcc attttgtttt tctgataagc aaactaatat atcagtcaaa
    15661 ctcattctaa cttatgtagt tagcgctttc attaaagggt gaccataaat gttcagtttt
    15721 caattaaaaa accttaatta tgctatttta gacttatacg ttattgtcct gtttcatttg
    15781 atggaggatt gtaaataaaa aaagaggaaa gaacataact tttcgttatc ttctttcctc
    15841 tttataattg tttagcttat ttagccaaag cttcttttgc ttggtcagcc aatgcagtaa
    15901 atgctgctgc atcgttaaca gccaagtcag ctaacatttt acggttgatg tcgatttcag
    15961 caactttcaa accgtgcatt aattttgagt agctcaagcc attcatacga gctgctgcgt
    16021 tgatacgagc aatccacaat ttacggaagt cgcgtttctt ttgacgacga tcgcgatatg
    16081 cgtagttgta tgaattcatt acttgttctt ttgctgtttt aaataaagtg tgttttgaac
    16141 cgtagtaacc ttttgctaat tttagcactc ttttacgacg tttacgagtt actgttccac
    16201 ctttaacacg tgccatgtat aattcctcct aataaaaata aatcttcaga ttctgttatt
    16261 tgtacttctt atttcatttt tgctagttgt tggcgaatac gtttgaagtc gccactagaa
    16321 accatgcttg ctttacgcaa ttgacggcgt tgtttttttg ttttgccgtg gaaacggtga
    16381 cttgtaaacg cgcggaagcg tttcaatccg cctttaccag tacgtttgaa acgttttgct
    16441 gatccgcggt gtgttttttg ttttggcatg actatatttc ctcctcaaaa tctttcgtta
    16501 tccgactatc ggctgtccaa cagccagtta gtcattcaaa ttacttactg tcgtttttcg
    16561 gtgccagcgt caagaacatg ctgcgtccgt ccattttcgc tttttgttcc actgttgcaa
    16621 tatccgcagt ttcttcagct aagcgattca agactttttg accaatttct ttatgggtaa
    16681 tggcacggcc tttgaaacgg atagaagctt tcactttatc gcccttttcc aagaacttac
    16741 gtgcattacg aagttttgta ttgaagtcat tcaagtcgat cgtaggactt aagcgaactt
    16801 cttttacatt gatcactttt tgttttttac gcgcttcgcg gtctttcttt tgttgttcga
    16861 aacggtattt accgtagtcc atgattcgcg caactggtgg tttcgcacca ggggcaacta
    16921 acacaagatc caagtttgct tgttctgcaa tattcaatgc ttctgctttt gtcttaactc
    16981 ctaattgctc accatctgaa ccgatcaatc gtaactctcg tgcacgaatg ccgtcgttaa
    17041 ccatcatatc ctttgctatg gtcattcacc tccaaatatt atgagagaaa gaaaagctta
    17101 ccgaataaac ggcaataaaa aaacgagttc tcttacagaa cccgcgcgta cttcacctaa
    17161 tagaaccagt gaaaactatc tagcccagtg acattatcaa ctaaggcgag aagcgggtgc
    17221 ttctgctttt atttctcaac catcatagta tagcaaaaac taatcttttt gtcaatgttt
    17281 ttcatacagt ttgtcttcct tttctgaaaa tgattagatt agcagacttt ctagcagtga
    17341 ttcccgcttc tttgctatac taaagaaaaa cgaggtgaac ccacatgaaa aaaatcgaac
    17401 ctattccacc ttctcttcct cttcttacaa agggagagtt ttatttagaa gatgaggaga
    17461 tcttctctgg tcttctgatc aacgggggtg accaaagcta tctcgatgcc aaaaatatgg
    17521 tattaagaga gagtcatatc caaaaactta cgatgcaaaa aacagtttta cgtcattttg
    17581 aatgcagtaa tgtcattttt gaaaaatgtg atttttccaa tctggagtgg attggtggca
    17641 gtttccacca agtcgtgttt catcaatgta aattaacagg tacgaatttt gccgaaagtt
    17701 atcttcgaga ctgtactttc actgattgta ttgcttcgat ggcttccttt agtagtacaa
    17761 acttgaaagc tgtctccttc gatcattgtc aattagaaga cagcgaattt tatgaggtca
    17821 cttggaaaaa cctttttttg tctgacaatc agttgaccgg ttcgaactgg tttcgaactt
    17881 ctctgaaggg attagacttt acgactaatt tcttcacagc aatcgcttta tctcaagatt
    17941 ctttggcggg actaatcgtc aaccaagagc aagcacttgt gatcgcccaa gcccttggtt
    18001 tgcagatcaa agactagatc aacgaatccg ccgccacagt gcaataagca tccaaataga
    18061 taagaccaaa ctgatgatca aggcgattcc ccatccgaaa acggaatggg taaagggtaa
    18121 ctggagattc attccgaaga atcctgtcac aatagttgga acggtcaaga tcagcgacca
    18181 gaccgtcaaa aatttcatcg tgtcattcaa gttgttattc agcaaattat tataagtgcc
    18241 agagagctgg tctaaaatct gcgaagctaa gttcgtcatt tcaactgctt gtcgtgcttc
    18301 gatcagcgca tcgtccaact cttctttttc cttttctgac aacttgcgat aaatagccaa
    18361 tgccttgatt tgttctaaaa gtactacatt ttgttttgtt cctgtaacta agtaaaccaa
    18421 accgatctct aaatctgaaa gttgcagcag attcttgttc gttgtttttt ctcttaattt
    18481 cagattaagc cgctgacgtt cactattcac ttcctcgatt aaaggaaaaa aggaatcaga
    18541 aatcaaaaac aatgtacgaa acaataaact gtatacactc atgtctggca ttcgttccaa
    18601 aagcgatcga attagtcgaa tcacgtactc ggtattcggc gtggtaaatg taaacaaacc
    18661 gtcttctttt aaaataaaag cgataggact agtttcataa tgattatcga ctttttgctg
    18721 gtgcggaaca tttgatacaa gcagtaacgc ttcatcaaaa gaatcgtact ctacgcgcgc
    18781 ccgttcattt ttatctagag aataagtcag catctcgtca ctaatgccat attcttcttt
    18841 taagttttta acagctagca catcgttttg ctgtacattg atccaaaaat tacggtcttg
    18901 attaaaatag tgtttttccc gcatactcta tcctcctgac atttgtttcc agtataaaga
    18961 aaaaagtcgc tcaaataaag gtttaccctt tatttgagca actgtaaatc aaatggctac
    19021 tttggtttgg cgaatctctg ctaatttttc ttcgatcatt ttcaagactt cttcttttgc
    19081 ttgaggatct tccacaaaat tatagcggtc tccatcgatt tggatttttg gactttcttt
    19141 gtattcttca taccattgat cgtaacgtct gttcaattct ttgtaataat cgtatagact
    19201 tggatcaaag gacaattgtt catacgaacg accacgtttt tcgatacgct ccaacatcgt
    19261 atcaaaagat acacgaatat gaactaataa atccggatgt tttttatggg cagcataggg
    19321 aagttcttcc atcatgtttt ccagcagttc atcatacaca cgaacttctg tttctgttgc
    19381 tcttcctaga tctgcattta gatggaaaag cagtgaatct tcataaatcg aacggtccaa
    19441 tacattattg tcatctttca ttgcttgttt gatgcttgca aaacgtttat tcaaaaaata
    19501 aatttgcagc aaaaaagcat actgttcagg gtttgcataa aataagggca agacttcatt
    19561 atcatcaatc gattcataaa atgcctgact atcaaagtgt tcagccatca tttctgttaa
    19621 acttgatttt ccggcaccaa ttgtacctgc taaaacgatc acgctcattt acctccagct
    19681 cacttcatca ctaaatattg tgtttaactc caaccttttt aaatataccc ccaatatcta
    19741 gtagtgtcaa ttgtattttt ttctagtcaa agaagaaaaa aagtcaaaaa attcttaaga
    19801 aaaaagtgtt ttttctttag aaaacgtatt cttagtttta cttctgagat ggttttagta
    19861 aaataaagga ggaatgtttt ttgagaccct tagtggacaa aaaaattcgt gaagcagcgc
    19921 aactcgtttt gggcgcttta ttttttgctt aaaaatcact tttacgtgag aaggagttag
    19981 attatggcaa actatggcca aggagaatca agcggaaaga tcatattgat gggcgagcac
    20041 gcggttgttt atggagaacc agcgattgcc tttcctttct atgcaacaaa agtcaccgca
    20101 ttccttgaag agctggatgc aatggacgat caactggttt cttcctacta ttcaggaaat
    20161 ttagccgaag ctcctcatgc attaaaaaat atcaaaaaat tattcattca cttaaaaaaa
    20221 cagcatgaca tccaaaaaaa cttgcaactg accattgaaa gcacgattcc tgctgaacgt
    20281 ggaatgggat caagcgctgc agtcgccaca gcagtcactc gtgcttttta tgattactta
    20341 gcatttcctt tgtctcgtga aatactatta gaaaatgtcc agctttcgga aaaaatcgcc
    20401 catggtaatc ctagtggaat cgatgcagcc gctactagca gcttgcagcc gatttatttt
    20461 acaaaagggc atcctttcga ctacttttct ttgaacatcg atgctttttt gattgtcgct
    20521 gatacaggaa tcaaaggaca aacaagagaa gccgtcaaag atgtcgctca cctctttgaa
    20581 acccagcctc atgaaactgg acaaatgatc caaaaattag gatacttgac gaagcaagca
    20641 aaacaagcaa tcattgaaaa ttcaccagaa acgttggcac agacaatgga tgaatcacaa
    20701 tcacttctgg aaaagctgac aatcagcaat gattttctta atctattgat ccaaacagca
    20761 aaagataccg gggcattggg tgccaaatta actggcggtg gacgcggtgg ctgtatgatt
    20821 gcattagcac aaacaaaaac aaaagcccaa gaaatcagtc aagcacttga agatgcgggt
    20881 gctgctgaaa cttggataca aggattagga gtacatacct atgtttaaag gcaaagcacg
    20941 cgcatatacc aacattgctc taatcaaata ttggggtaag aaaaatgaag aactcatcct
    21001 tccaatgaac aacagccttt cgttaacatt ggatgcattt tatacagaga cagaagtcat
    21061 cttttctgat agctatatgg tagatgaatt ttatctagat ggcaccttgc aagacgaaaa
    21121 agcaacaaaa aaagtcagtc agtttcttga cctttttcgt aaagaagccg gcctctcact
    21181 aaaagcttca gtaatcagtc agaatttcgt tcctaccgca gctggattag cctcctctgc
    21241 cagcgggcta gctgctttag caggcgcttg caatactgct cttaagcttg gattagatga
    21301 tctctctctt tcaagatttg ctcgacgcgg gtctggttca gcttgccgaa gtattttcgg
    21361 tggtttcgtc gaatgggaaa aaggccatga cgacttaagt tcttacgcta agccagtccc
    21421 ttccgattct ttcgaagacg atttagcaat ggttttcgtt ttgatcaacg accagaaaaa
    21481 agaagtgtcc agcagaaatg ggatgcgtcg gacagtcgaa acatccagtt tttatcaagg
    21541 ctggttagat tccgttgaag gggatctata tcaattgaaa caagcaatca aaacaaaaga
    21601 tttccaactt ctcggagaaa cgatggaaag aaacggacta aaaatgcatg gaacgacttt
    21661 agctgcccag cctccattca cttactggtc tcctgacagc ttaaaagcga tggatgcggt
    21721 gcgacaattg agaaagcaag gcattccatg ctactttacg atggatgctg gccctaatgt
    21781 caaagtttta gtggaaaaca gccatttatc tgaggtacaa gaaacattta ccaaattatt
    21841 tagcaaagaa caagtaatta ctgcacatgc tggtccagga attgcgatta ttgaataaag
    21901 ggagattttt atgattgaag tatctgcacc aggcaaactc tatattgccg gagaatatgc
    21961 agttgttgaa acaggccatc cagcagttat cgctgcagtc gatcaattcg tgacagtcac
    22021 tgtagaatct gcacgaaaag tcggaagtat ccaatctgca caatatagtg ggatgcctgt
    22081 acgttggaca agacgcaacg gagaattagt tttagatatt cgggaaaatc cttttcatta
    22141 tatccttgct gctattcgct tgactgaaaa gtatgcacaa gaaaaaaaca ttcttttatc
    22201 cttttatgat ctgaaagtaa caagtgagtt agacagttca aatggccgga aatatggatt
    22261 gggttctagc ggtgccgtga ccgttgcaac ggtcaaagcc ttgaatgttt tttacgcgtt
    22321 gaatttatct cagttggaga ttttcaagat tgcagcacta gccaatttag cagttcaaga
    22381 taatggttcc tgcggcgaca tcgctgctag ctgttatggt ggctggatcg ctttctcaac
    22441 cttcgaccat ccttggctcc aagaacaaga aactcagcat tctatcagtg agttacttgc
    22501 cctggattgg ccaggtctat ccattgagcc attgattgct cctgaagatt tacgtttatt
    22561 gattggttgg acgggtagcc ctgcctctac ttctgatttg gtcgatcaag ttcaccgttc
    22621 gagagaagat aaaatggtgg cttatcagct tttcttaaaa aatagtacag aatgtgtcaa
    22681 cgaaatgatc aaagggttta aagaaaataa tgtaacgttg atccaacaga tgattcgaaa
    22741 aaaccgacaa ttactgcatg atttatctgc aatcactggg gtcgtcatcg aaacgcctgc
    22801 tttgaacaaa ttgtgtaatt tagctgaaca gtatgaagga gccgcaaaat cttctggtgc
    22861 aggtgggggc gattgcggaa tcgtaattgt tgaccagaaa tctggcattc ttcctttaat
    22921 gagtgcatgg gaaaaagcag aaatcactcc actgccgtta catgtctata gcgatcaaag
    22981 aaaggaaaac cgatgaatcg aaaagacgaa catgtttcac tagctaaagc ctttcatgat
    23041 aaacaaaaaa acgaatttga cttcgtacgg atcatccata accctttgcc gcaaatagca
    23101 gtttctgatg tcgatctaag tacacaggca gttgggttta cactaagcag cccattttat
    23161 atcaatgcga tgactggcgg aagcgaaaaa acaaaaaaaa tcaaccaaga tcttgcaatc
    23221 gtcgcaagag aagcagattt gatgattgcc actggttcag tcagcgctgc cttgaaagtc
    23281 ccttctttag ccgatactta tacgattatg cgacaagaat atcctcacgg gaaaatcatt
    23341 gccaacatcg gtgcagggac ttctgtcgaa agagccaaag aagctatccg attgtttcac
    23401 gcagatgcct tacagattca tttgaatgca cctcaagagt tggttatgcc tgagggagac
    23461 cgtgatttta ccaattggaa agtacttatt caagaaactc aaacagccat tgacgtcccc
    23521 ctcatcgtaa aagaagtcgg ttttggcatg acaagagaaa cgctcaatga tctagctgct
    23581 ttaggagttc atacagttga tatcagcggt cgaagcggaa caagcttcac ccagatcgaa
    23641 aacgcccgtc gctccaagcg ggaactgagt tatttagctg actgggggca atcgacagtc
    23701 tcttcattgc ttgaagcaaa tgaagcagac acttctatgg aaatcctagc ctccggaggt
    23761 atccgcaatg cctatgacat atttaaagcc ctttgtctcg gcgcaaatgc cgtgggtact
    23821 tcaggaaccg tactgacgca tctgatgaat cacggcgtag aagaaactat tatactgatg
    23881 aagcaatggc aagaagagct tcgtctgctt tatactatgg tcggcgcaac gaataccgcg
    23941 gccctacacc aacaatctct gatcttttcc ggaccagtga aggattggtg cgaagcaaga
    24001 gggatcgact tagtgaagta tggaagacgc acagaaaaga gcgtgggaca aaagtaaaga
    24061 acacttttgt ctcacgctct aaacacgtac aaacggcgga agtaaaagca actccttcgg
    24121 aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaattcct tcttatttct
    24181 tggagttaaa tgcttctgtc ccagcctctt ttttcgaata aatgatgttt aatcagctgt
    24241 ccttcggtat tcgttcaatc cgctgatttc acaacctctc cactaaacag tgtactaaag
    24301 ctcttttaag gttgttttcc gatataggca agtatgcctc cgtccacata caagacatgg
    24361 ccgttaacga aatcagatgc gctagaagcc aagaagacag atggtccagc caaatcgatt
    24421 ggctcgcccc agcgtgctgc tggcgtacgt ccaacgataa attgatcgaa tggatgacgt
    24481 tcaccgtttt cttgtgtttc gcgtaatgga gcagtttgcg gtgtagcaat ataacctggt
    24541 ccaattccat tacattggat attgtattga ccgtattcag aagcgatgtt tttcgtcagc
    24601 atttttaatc cgccttttgc cgcagcataa gcactgaccg tttcgcgtcc taattcactc
    24661 atcatggagc agatattgat gattttaccg ccgccttttt cgatcatatc cggaataact
    24721 gcttttgaaa cgatgaatgg ggcatttaaa tccacgtcga ttacttggcg gaagtctgcc
    24781 gcatccattt cgatcatcgg tgtccgtttg atgatccctg cattgttgac tagaatatca
    24841 actgaaccta catcttcttt gatctgttga accatcgctt gaaccgcttc ttcatcggtc
    24901 acatcgcaga cataaccttt tgcatcgatg cctgcttctt tataatgcgc tataccttca
    24961 tcaactgatt cttgattcaa gttattaaat acgatttttg ctcctgctgt agctaaagag
    25021 cgtgcaatct caaatccaat accatagaca gcaccggtga ctaatgctac ttttccatct
    25081 aaacgaaaca tatccatact aaattccatc attttctctc ccttatgctt attttaattg
    25141 atccatttgc accatatcca tgtctgtata ggtgatattt tctccgcaca ttgcccagat
    25201 gaatgagtaa ttgcttgtac ctacacctga atggatcgac cagcttggcg aaataatggc
    25261 ttgttcattg tctacaacta aatgttttgt ttcatctggt ttgcccatca tgtggaacac
    25321 acgtgtatct tcattggcat aatcaaagta gacataagct tccatacgac gttcatgtgt
    25381 atgacaaggc atcgtattcc aagcgcttcc tggttctaaa atcgtataac ccatttgtaa
    25441 ttgacagctt tcgcatacat ttggatggat gtattggtag attttacgtt cattcagtgt
    25501 caggccttca ccagtctcca ttggttttac ttggtcgata ctgattttta catttggata
    25561 tttatgatga gctggaacag aactaatata gaatttagct gggttttcag catcttgaga
    25621 agaaaataca acatgtcgtg tttcttttcc gatatagtat ccgtcttgtt ttttcatttc
    25681 ttctttttgc ccatcgatct cgatgaatcc tggtccaccg atattgatca cacctagttc
    25741 acgacgctct aagaagtaat caacacctag ttctttgtct aatgtgattt ctaattcttt
    25801 ttcagtaggt gtcactccac caaagatcat tcgatcgttg tgcgtataag tcaaactgat
    25861 tttccctggt tcaaatacct tttctactaa aaattctttt ctcaattgtt ccgttgaata
    25921 atgacggata tcttctggac tgtgtgtata acgtgtttcc atttcttgca ttttcttcta
    25981 ctccttctat cgaatgattt ttccagagcc gcatgctaaa aattgtgcga cttcttcttg
    26041 actaaattgg ttgcagtccc catggatcgt atgcttcaag gcagaagctg ccgtagcaaa
    26101 atcaatgatt tcttgcggag acatattgga taaaatccca tggagcacgc cacctgcaaa
    26161 agcatctccg ccacctactc gatccacgat tggggtgatt ctatggactt gggattccac
    26221 atattcatgg ttcatccaca atgtcccctt caattcattt tcacttgctg aatgaacggt
    26281 acgcttggtc gaataaaaca cctgaatatt cgggaacttt tcctgcattt tttgataata
    26341 ataaattaga ggttgttctt ctgcttctgg cgctttctcg atacctaaca aataaagagc
    26401 atccattttt ccagctgagc agatatctac taaaggtaaa agctgatgga ttacttcgct
    26461 ggcttcttgc tgtgtccata attttccacg atagttgata tcgaagctga tcaggcagcc
    26521 agcttttttt gcagcttcta tcacctgttt cgtcattttt tgccattttt tagacaaagc
    26581 tggggtgatt cctgaaacat gaaatatatc tattccttgg aataactcct ctagcgacca
    26641 ttccaaatga tccatttcag caaaacttga tccggcacga tcatagatca ctgaggcggc
    26701 gcgttcgcca ctaccagttt ccatataata agtacctagt cttgatccac cagataatac
    26761 ctgtttcgta tctactccat aacattgcaa gtgctttttg actgcttttc ccaatgcgtt
    26821 atcaggtact tttgtagcaa aaatcgcttc atgtccgtaa ttagctaaag aaattgctac
    26881 gtttgcttcc cctccgccat aatgggcagc gaatcgttca cttgaatcga tacgggttcc
    26941 ctgctctgtg gacaatcgca acatgatttc tccgagtgtc actacttttc ccataagcag
    27001 ctacctcttg atttctttca tttttgctgc atactgttgc gcgacttccg ttactttgtc
    27061 aaaatctcct gtagctgcgg gtgctaaaag gttcccacct actccgactg ttacgacacc
    27121 agcatcgaac cactctttca tattgtccag actcacaccg ccagttggca tgatattgac
    27181 ttgaggcatc ggcgccttga aggcagaaat gatacttggt ccataagcgc ttccaggaaa
    27241 tagtttgacg atatctaccc cgcttttcag cgctgttttg atctcggtaa tagtcataca
    27301 tcctggtaag taaggaattt gatacagatt gcacatctct gccgtttctt gatcaaagga
    27361 agggctaaca atatactctg cgccagctaa gatagccaag cgagctgtga cagcgtctaa
    27421 tactgtgcct gcgccaatca ctatttctgg ttggtctttg tagaatgaca aaagttcttt
    27481 gattacttga tctgcttgag ggactgtaaa agtcaactca ataccagtta gaccaccttt
    27541 gatgattgcg tggcaagcat tcaaagcttc ttctttgctt tttccgcgta ccaccgcaat
    27601 cactccggcg tttttcaatc gagataaaat atcaattttt ttcatcttct ccacctattt
    27661 cctatttaga aattttattt tataacttgg aaatctatac ccatattata cggcagaaaa
    27721 gaaaaattgc aaacgctttt ttcattattt ttgaattctt tgctcgattt cgctttttgt
    27781 ttgcttgagg gcactgatta tttgttcttt tgtctcatct gttaaacgat atttcggcat
    27841 acttacacta aatgcaccaa tgatttgttc gtttttcacg attgaggctc ctatacaaaa
    27901 aatatcacgt tcgatttctt catcgtcaaa tgcgatgtgg gtttctttta ccgttttgat
    27961 ttcctttttc aaccgtaatg cattggtgat cgtatattct gtgtaaggga tcaacggatg
    28021 cttttcaaga taatcagtgt actgctcttc actgaattct gctaatacgg ctttgcccat
    28081 cgcagaattg tataatggtc gggtgattcc gatttttgaa gacatgcgga tcgtttgatg
    28141 ttttggatct agtttgttca cgtacaagat ctcattgttg tccaataccc ctaagtggat
    28201 agtctcatcg atcttttgct gcagctgttc taaaaacggt aaagtcaact ctaccaaatc
    28261 gatttgttca atgtttttat tcgcgtagcg aataagcttt gcacctaaac gatagttttt
    28321 ctctgaattt ttatttacgt agccgatcat caacaaagta tctagtattt tcaagactgt
    28381 agaagaggtc attcccacac cctttgcgat cgtctgcaaa gagacatctt ggttttccgc
    28441 taaatagtct agtattttag aggctttgat caatacagtt ccataaggct ttttattttc
    28501 catataatat tctcctattt ctttataaga aaaattatag cggaaatacc atcaatttaa
    28561 aagagatatc cagatataaa ctaccatttc tctttacagg caatttaatg ttgaagatcc
    28621 gcttcgtttt tacatcaaac tttgatataa agcaatgatt tcttctactg tcgtttctct
    28681 tggatttcct ggtgtgcata catctcgcaa agcatcttct gcaattgctg gaatatctgc
    28741 ttcttttaca cctaattcag aaatggtttc tgggattcca accgctttgc tcaaccgatc
    28801 gatctcacca caagccgctt ctcttacatc ttctaaagac atttcagctg ctcctttaat
    28861 ccctagaaca agagcgatct cacggtactt ttctccagta tattctttgt tatatttcat
    28921 gacagttggc aaaagtgctg cacacgctac gccatgagga atgttgtacc atgcacttaa
    28981 cgggtgagcc atcccgtgta ccagtcctaa accgacattt gagaagccca ttcccgcaat
    29041 atactgtcct aatgccattt tttctcgccc attttgatcg ccatctacag aagcttccaa
    29101 agaatggccg atgatttcga ttgcttttaa atgcagcata tcagtcattt cccaagcgcc
    29161 ttttgtgata aacccttcaa tagcatgcgt catagcatcc atacctgttg atgcagccaa
    29221 ttttttcggc attcccatca tcatatcgct gtcgatgaac gcgacgattg ggatatcatg
    29281 aggatcaaca caaacaaatt ttcggtgatt tacttcatct gtgatgacgt agttgatcgt
    29341 tacttctgct gctgttccag aagtcgttgg tatagctaat ataggtaaac atggattttt
    29401 cgtatcagca acaccttcta aactaatgac gtctgaaaac tctggattcg tcaaaataat
    29461 cccaatggct tttgccgtat cgattggcga acctccaccg attgcgatca aacagtctgc
    29521 ctctgcctct ttaacaaaag ccactccatc ttttacattt tggatcgttg gattaggtac
    29581 gatcccgtcg tataaagcat aagcgattgc tgctttatct agaagttctg ttacttttgt
    29641 tgctataccg tgctcgatca atcctttgtc agtaatgaca gctgctttgc cgaatcctcg
    29701 ctgctgaaat tcagggacga tcgactcaat cgctcctttt ccaaaatacg atgtttcatt
    29761 taaaatcatt cgattactca ttttctattc ctcctaattt gtattatttt tcacaataaa
    29821 aacgaaagaa ccccaagcaa ccggttgccc agttgcttgt tgctacagtt caaagactgg
    29881 catcaattcc caactgactg gagaggcatc tggatttgtc tccatgatat cttccatgta
    29941 cttccaccat ttttgattga tagatgtatt tgccattttt tcccataact tttcatcttc
    30001 gatcactaag taaccaaata acaaacttgt actcggatca agatagatcg aatagtcgat
    30061 gaccccgtgt tcacgaagtg ctgtacgcat ttctggccaa agttcatcat gtcttttttt
    30121 gtattcttct tgtttttctg ggtaaacttt catgcaaaaa gcttttttca ccatgtcaga
    30181 cacctgcttt cgtatgaact tcctccaaat aacctgcttt tggagtgaca ccaaacgcat
    30241 ctgctaaatg ccacaggttt tcgtccgtga ttgtttgcaa gattggtcct tgcgctttga
    30301 cgtacgtata gacttctgct gccttttctg ctgtctcgat caaaccaaag acttcatcca
    30361 tgtcttttcc tgacccgtag attccatgtt gtggccataa aaccaatcga gtttctttca
    30421 ttttttcagc tgttgcttcc ccaatctcat ttgttcccgg aaccatccac ggaatgatgg
    30481 aaattccttc tggaaaaaca actaagcatt ccgtacacat ttgccatagc gtacgactaa
    30541 aggaacgttc gtctaattca tgcgtaaaac tcatcgctaa tagatgacta gcatggcaat
    30601 gcataacgat ccgattatct gggtctactt ctaaacgggc gatatgactc atgaaatgac
    30661 ttggcaactc gcttgtagga aggcattcgt tttccagccc ccacaaaagt tccagtgttt
    30721 tgccatcttc agcaactcga acgattccaa gattctcggc aggttcgctc gctacatttt
    30781 taaaatatct tcctgaacca gttacaataa aatagcatcc tgctaaacgg ctggcatcaa
    30841 aaatcatcga gatgcggcgg atcacttttt caggatccaa gaacggtgtg atctcttctt
    30901 cttttagtaa ataagaaata ttcccgccat ttctttcatc ccatcccaag cgataaagat
    30961 tcgacgtcgt ttcgatcatt tctttcacat aaggcgcttg taaaatatct atttttttca
    31021 atatagccac actcctattt tcttaattcc aacacgtctt tttgatattc ctggacttct
    31081 tccagccaat ccaaaccaac tggaacttga tttttgtaac agaaataatt ccatacatcg
    31141 gcatacggga aatctttcaa ttcttccgta taagccattc ttgaagtaaa gtcaaaagcc
    31201 agctccattt ctttcaatcg ctcaactggt tccagcatag ctttcagcag tgctttttgt
    31261 gtatttctcg taccgatgac ccaagcagcg atacggttga tcgttgcatc aaagaaatcc
    31321 agaccgatat ttgttttttc caacaattcg ttacggacta attctttagc gatttcctgc
    31381 aattcatcat ccatcaaaac cacatggtct gaatcccaac gcactggacg ggaaacatgc
    31441 aacatgattc ctttgctgaa taaagctaat gaagataatt tattggaaat cacttctgtt
    31501 ggatgaaaat gtccagcatc tagacaaaca agtttgtcac gagtcaaccc gtaacccata
    31561 taaaattcat gggaaccgac tgtataagct tcagcgccta aaccaaatag tttgctttct
    31621 actgcatctt gtacataccg ttcatctaac tcttctgtaa aaatttcatc gagtgattcc
    31681 attaaacgtt cccgtggggt aaaacgatca atcggattat ctttcatccc atcaggtacc
    31741 caaaagttat tgatacttgt ttgcccagtt tctttcccaa agtactccgc gattttgcgg
    31801 cttcttttcc cgtgttcgat ccagtattca cgaacttctt tatctggatg agccaatgta
    31861 aagccgtctt tcatcattgg atgcgaaaag aaagtcggat tgaagtcaag accgatttct
    31921 tctttttttg cccactctac ccatttttca aaatgtttcg gctcaatttc atttagatcg
    31981 acagattctt ctgtatccaa atagatagca tgaaggttca atttgtgttt gcccggtatc
    32041 aacgaataag ccttctccag atcttgtcta agctcttcag gtgttcgtgc ggctcctgga
    32101 aaattccctg tcgccatgat tccaccggtc aattcgccat ccggtgtcaa gaaacctttg
    32161 acatcatctc cttgccagca atgcatagaa attttgatgt cctgtatctt ttctagtaca
    32221 gcatctgtat ctacaccgat agttgcatat ttttcttttg cttgttcgta atttctttca
    32281 atcgtgttca tacgattact cctttgattt tattcacgta ccattccatc gtgttttgct
    32341 tattttcatc tgggtaaaaa gtttcacatg gaaacgactg tttgattaca tttcttgctt
    32401 gttctatatt cgaaaactga cctgtactga gcatttgcat ggcaacattc ccgattgctg
    32461 tggcttcact aggtcctgct tctacaatga ttccggcata atctgctgtc aattgattca
    32521 gtagacgatt attcgatccg ccccctacga tgtgcagctt ttccaatttc gttccagtta
    32581 agtgttctac tttgatcagc tcttgtgcgt aacaaagagc aagattatca tacacacaac
    32641 gagcgatagc tcccgatgag acagggactg gctgctctgt ttcaaaacag tattgctgaa
    32701 tctcttctat catatttggg ggattcaaaa atcgagggtc attgatttcc atcacttgct
    32761 gcagcggttt ttcttttgca gcaagctctg ccaattccgc ataactgtac tcgtactctt
    32821 gcattcgggc aacttcctgg atcaaccaca tccccatgat gtttttcaaa aaacgcaccg
    32881 tgttatgggc accccattca ttcgtataat tttcagaaaa agcattgcga gaaacattgg
    32941 cgatctttgt ttcaatccct aaaagcgacc atgtcccact gctgatataa ccccaacgtt
    33001 ctccttgacc tggcgttcct aatacagctg acgccgtatc atgacttgct actgtgataa
    33061 aggtcacatc tggcaaatca tattttgaaa attgttcttt ttgcagatct cctagtatcg
    33121 ttcccggctc tgtcaatggt ggaaataatt ccttcgagac accgattttt tcaagaagtt
    33181 ctatttccca ttcttttgtc cctgcattca gcagctgcat agtagatgca ttagttttct
    33241 ccgtcaccat gttaccagta aagacatacc ctaaataatc aggtatcagt aacaatttat
    33301 gtgcttttgc caaattttct ttttcttcag caaacaattg gaacaaggta ttgaaaggct
    33361 ggatctgaat ccctgtctgc tcatacaact tatctagaga atagatttca gaaaactgtt
    33421 ctactgctcc attggtacgc ttgtcccgat aagcaatcgg atcatttatc cgatcccctt
    33481 gttcatcaat cagacagtaa tcgactgccc atgtatcgat ccccgcaaaa aggcgatcaa
    33541 tccctgtctg ctttaatttt tcaaatccaa tcaaaatctc tttgataaga taatcgatct
    33601 tccagcgatc gtgaccgtct ttgttccgaa agccgttttt gaaccggtgt acttcttcca
    33661 agatcaaaga accttttgca tccctcgtac ttttcattag tcgtccgctt gatgcaccga
    33721 tatcgatggc aacaaatgtt ggattcattt ctccacctct tttactttat tgttgattag
    33781 cactttatta ataaagcgtt atcatttatt gacaatgcta tcataataca gaatcttata
    33841 ttttgcttca cactattttg gtatataatt gcattatctt gacaagttgg gagtgtttac
    33901 atggattact gggaaaaagc caaccactca tggtcggaag actcaaaaag agtgatcttg
    33961 acgcctacac aaagaagcag gaatttattt ttttatatcc aagaaatcgg ttacttcaaa
    34021 gcaccaatcc cttactatac tgaacgagca catttacctt cttacttgat aaagtttact
    34081 ttgtctggca aaggttcgct tacatataat gataatcagc aacagctaaa agctggagac
    34141 ttatttttta ttgactgcca agaatatcag cgttatcaaa cgatcagcga agaaccatgg
    34201 gaaatggatt ggatccattt gaatggtcag aacgtccaat cattttatca ggagttcaca
    34261 aaagacggcc ataacacctt ccattcaaca ggagatccat cagaaaacaa gatccaccat
    34321 ttgatcacag aattgatcca catgcaacaa ggcacgaatg cccgtaccga tttccagtcc
    34381 tctgtagcta tccacgagtt gctgaatgaa ctgattttgc aaaagtatca gctagatttc
    34441 gaagaagagg atattcccgc ctacgtttac aaactgaagc aatacttaga cgaacatttc
    34501 aaagaaacga ttacacttga tcaattagaa caacaattct tattgaataa atatcagctg
    34561 agcaaagatt tttccaaatt tatcggttct ccaccaatcg attatttgat cagcaaaaaa
    34621 ctttcttacg ctaaagacct tcttcggtat acagaattta cggttcgaat gatttccgaa
    34681 gaaataggga ttgagaattt tgcttacttt agccgcctgt tcaaagcaaa aacaggacta
    34741 tcgccgagag actttcgtaa attcagctga ttcatataat atgtacgtca ttttttcaaa
    34801 atattttgaa atatatagat aaaaataaaa taaccgcagt ttctgcttct atgtaaacaa
    34861 cagcagctac tgcggttatt ttttagtgat cattctcatt gttcatcttc aaaatgttca
    34921 taatgaacca actgtttctg tgtatcacgt ttcaaaaatt ctttaggcgt tatgccgaac
    34981 tctctcttga atgctttcag aaaatgcgga taagaagaaa aaccactttt actatataca
    35041 gcactagagc tgcggtattc tcgcaacaag tgcttggcat agatcagctt tttcttcatt
    35101 acatactgat gaaacgtaaa tccagtgtac tttttaaatt ctcgtgtgat atggtatttg
    35161 ctgacaaaaa actgcttttc catttcctct aaagaaagcg gatgagataa attttttgag
    35221 atatattgta acatttgttc cacacgctca ttaggaacta cagcattctg ttcttgcgca
    35281 ctctcttctt tttgtacaac ttgattgaga aaaatcaagt attctaccag agcttgttca
    35341 tattttatgt cttcaccgta aattttttta tcaggaggat ggtcgataaa tgataatttt
    35401 tgcttcaata cttcctgttc tatttgcaat acacgactcc tcttctctcc cattggttga
    35461 aaacaagccg atagattaga ccatggcgtg gaacgacttt ctagaaaaga aggggtgaca
    35521 aagatataga cacgctcgaa tacatctgaa gattggcgga cgatacgatg caaatcattg
    35581 gaatggatga gcagcacact tcctgctttg atcgtaaatt gtcgtccgtt caaataaaaa
    35641 gtcgcttctc cctttaatgt agcatggatc tcatagaaat catgatgatg atagatcgtt
    35701 ttattttggc tgacgacatc tttgacatga tagatttcat actgatcaga aaccatcgta
    35761 ttgacttgtt caccgctgat tttcttttgg agcatgtgcc gcacctcctt ttgttcactt
    35821 atgcacaatt ttattatacc acgttttttg taatcaaaaa gagctgcttt tatatactct
    35881 tataaaaaag aagagacgtg gcatcttcta gccccgcccc ctccattcta aatattagtt
    35941 aaccaacgtc ttctttacat tattcaagaa gacttcttcc ataacgaatc ccatcatctt
    36001 ttgtttcttc aagaaccaca tacaggtacg gacgattctt catgatgatt tctttgattt
    36061 ttgtgtactc gatcacaccg tctcccaaat ttaccggcac gattttttcc tgttcgacac
    36121 gaaaatcttt caaatgaacc gcacatatct tttcaccaaa acgttcaaaa gcttcttcta
    36181 ccaattggac ttgttcttga taatcactac ttgtgatcaa attggtcgga tctaaaatga
    36241 ttcctagata gtccgaatct actgcttgga tcagctgctc tacccttgct aaagaataca
    36301 ccggatgatt caaacctggt tctatcccca ccatcatttg gtatttttct ccagctttta
    36361 ccaagcgacg gataacggac acagcttcag caaatgcttc atctgtgaaa ttttcttccg
    36421 tatattggat ttccggcaaa acacatccag tttccgaagc aaccatcgac gcaccaaagg
    36481 aagaagcata gcgaagatac tgctcgaact ttgtcagcaa ctcttgtcgt atcgttaaat
    36541 ctggatgaat catattgata tagcaactta aaattcctac ggtcacttct tgcttttcta
    36601 aaactcgttt gacataattt cccatcccag aattgatctc atttgcgcca gaaggtattt
    36661 caggaaacga aagacctaag gcgagctgca gtgtatgaat cccttgttct tttgtttttt
    36721 ctgcaagatc ttctatcgtt tggacttcgg aaagatcatg tcctctaatt gtaatgttca
    36781 acataactat tctcctaact cagcatattg ggtagccaca tgacgatttg cgggaagtaa
    36841 gtaatcaaaa acaagacgac taagataacc ccataaaaag gaagaagcgg tttcagcatt
    36901 gcctctgctt ttacgcctcc tacacttgca ccgacatata gtcctgtacc tactggcggc
    36961 gtgatggagc ctacacacag attcatgatt gaaaacaacc cgtaatgtac aggatcaacc
    37021 cctacacttg tgacgattgg taaaaatatt ggtgtaaaaa tcaagatagc aggcgccaca
    37081 tccataaaca tacccaccag taataacaca agattgacta ataacagaat aataaattta
    37141 ttatccgtta cgcccataat caacgaacta attgcctgag gaataccggt aaacgccatg
    37201 gcgaaagaca tcatggaaga agtagccaat aagaacatga tcgtccctga cattgctact
    37261 gattgaaaca acatattagg tatatctttt agttttaccg ttttatagta aaacatagca
    37321 atcaacaggg agtaaatgac agctatcgct gaagcttcta ctgctgtaaa tatccccgtc
    37381 aagataccac cgataatgat gacaatcaat agaaggctag gaatcgcctc ttttattatt
    37441 tttccagcat gagccatctg tcctttttcg acaacagggt atttattctt tttagcaacg
    37501 atgaatgcta ctagcatgat tcctagcgcc cacaaagcgc ctacgagata acctcccata
    37561 aacaaagcag agatcgaagc accaccagca acaagtgaat acatgataaa agcagtactt
    37621 ggaggaatga ccatacctgt cggagctgac gcgatattga ccgctgtcgc aaacttccgg
    37681 tcatatcctt cttccacttg ctgagggatc aacactccgc caatcgcggt agaagcggca
    37741 atggccgagc tagagatgga accaaataaa gcattcccta acacattcgt atgagccaaa
    37801 gcccccggca cgcgcccgac gaacaacatc gcaaaatcca ctagtttctt agctatccct
    37861 ccattattca tgataatgcc cgagagaacg aaaaacggaa tagcgatcag cgaaaaacta
    37921 ttgatacttc ccaccatttt ttgagctgaa ctaaaagcag aaacatcaaa cggtataact
    37981 aacaataaag tcatcatcga tgagaatgca atacttatag caatcggcat ccctaataca
    38041 agcaacacaa caaatacaaa aaataacact aatccggctt ctattgccat tttattcctc
    38101 catttttata ttttttcttg aattgctggc ttgttgctta atgtatcgat tagattgatc
    38161 aggctataga taatgatgag tacccccgat acaggtactg acagataaac atatcccata
    38221 ggaatactta aagaaggcga gatctgcccc attgtcaatg tgacagcatt ccatccgcca
    38281 tacaccatga tcatcgcagc aaataccaga aataaacttt gaacaacaac ttctaaaatt
    38341 ttactttttt tgccagttaa tttttcactt aaaaccgtta cggctaaatg tgctttttgt
    38401 cccacaacat acgcggaaga caacatggca aaccagacaa gaccgaatcg aacaagctct
    38461 tccgtgaccg tatttggatt tcctaaaacc gttctggaaa atacttgcca taaaacaaca
    38521 gcgaccatcc caacaagcaa aacagctccc aggatctcta ataccttgtt taaaatcatt
    38581 ttcatcacag ctacgctcct tgctcttgga tcttttgata aaggtctttg taggtaggat
    38641 cgtttttgaa tatatcatga agtggggcaa ctgcctctcg aaacggtgta ttatctacat
    38701 cattgaattg gactccatgt tcttcttgtg ctaaagcttt ttcttcttca attgcttttg
    38761 caaaagcttc aatttcaaaa accgttgatt ctttcgctgc ttcttcaatg gctttttcct
    38821 gctcatcagt tagctgttct ttgatggcat cattcatgat gatgatatct ggcacacgtg
    38881 tatgctcatc ataggaatag tatttagcca caccaccatg tccagctgta tacaagacaa
    38941 attcattgtt ttctgatccg ttgatcaaat tggattgaag agacgtgtac acttcatcac
    39001 ttcccatagg tacgggcgaa ccgcctaaaa gctctaccat tttgatagcg gtttcgcttt
    39061 gcatcacacg gatcttcttt cccttcaaat cttccggcgt atggatcgga ccgtctacca
    39121 tataaaagct gcgctgacca gaatcataat aggtcaatcc ggtaaatcct aaatttttgg
    39181 tcgattggta gattggctcc attatttctt cattatccat caccttaaag aaatgttctt
    39241 catcattgaa tagataagga actgaaaaaa tcgaataatc tttagagaaa ctttccaacg
    39301 ctgaggcact tacttttgtg aaatctactg ctcctgactg tgtcaattcg atcagttcac
    39361 gttctccacc cagttgtcca tctgggaaat actggatctg tacggaacca tctgtttttt
    39421 cttttactaa acgcccaaat tcattcattg catcaattac tggctggctg ttgcttgcat
    39481 aagcaaagcg caaggtaact atctcattta catctgcatc tgcgacagtt gccacactag
    39541 aattatttcc gcagccgctt agacctagca gacctaggct aagcgaactt gctgcaaaca
    39601 gcagtgatgt ttttttcata tgggtttcct ttcttttaac aataagagac gagcaattct
    39661 gtcaaacaaa gcaccgttaa cgactgtcca taaggcattg ctgtgattcc gatattccga
    39721 taaaaatcta aactgtcccc cattcctgtc ccgattgaaa cgttttgaac ttctcctttt
    39781 tcatcgattt gttcaagcaa tccttggata gcacgataag cgacttcttt atattcttgt
    39841 ggtaaataac gtttatggac cgctttcaaa ataccgtaag caaatcctgc agttgcagaa
    39901 gattctacgt aagaagaagg atcatccaac aacgtatgcc ataaaccgct ttcagactga
    39961 taagttttta atgcacgcac ttgtgcttca agtgtttcga tcaataattt gcgcaatgca
    40021 tcttctttcg ataattctaa gatttcaatg atctctggaa tagcaatcgt caaccagcag
    40081 tttccacgag cccaaaatgc ttcggcatag ttatgatttc cttcaaacgt ccagccgtga
    40141 taccacaatc ctgttcgttt atccatcaag tatttgatat ggatcataaa ctggtaacga
    40201 gcttcttcta aatattctgg gcgattcaac agtttcccga tttttgccaa aggaagcact
    40261 gtcatcatca atgtatcgtc ccacaactga ttcttatttt ccggtccata tgtggcatgc
    40321 tgtaacccgt cttcatttgt ccgaggcatg tcattcatga cccattctgc ccattgttct
    40381 aaataaggca aatagcgtga atctttcgtg tcttcataca agtaagccat agtcaatagc
    40441 ggtgccattg tattgacgtt tttgggcgga gcgccttctt ccatacgatc ctcaaaccat
    40501 tcattgacca cttgataagc gcgaggattt tttgtcatct ggtaattttt ataaatacca
    40561 tatagaccga caccttgtgg ccaattccac actgtccagc ttttgtcatc tactttcagt
    40621 ccatcaaagt ccaacaaaaa ttcaccatta tcgtctttga tcgttgtcag gttttcaacg
    40681 agcaggtcaa ttttttcttt cactaattct ttaggtacaa aaatctcttc tttaataatc
    40741 atctttacgc caccttttta aacgctttca ttttatatcc ttaatatagc agtaataccg
    40801 tccactataa atatcgcttt ttgaacaaaa actgtctaaa attgacctaa atgttaaata
    40861 acaaaagtaa ctttcagtta cttggaaatt aaaaaaagaa cttggagaaa caacgttttc
    40921 caagttcttt ttcatctatt ttcttatctt ttttctacgc tttcttttgc ttatccgttg
    40981 taagcatcaa tgatgatctg tttcaattca gagatcaatg gttctttcgg attagctgtc
    41041 gtacattggt cttcgtaagc taattcagcc atacggtcta cggttgtatc tagtgtttct
    41101 tgtgtgactc cttgagcttt tagactcatg ttgatgccga cagattttcc taattcataa
    41161 acagccgttg ctaaagcttc gactaattcc tctgttgttt cgcctttcag acctaagaat
    41221 tttgcgatat ctgcgtaatc tgtatctgca cggaaatagt catatttagg gaacatcgca
    41281 tgtttttgtg gatcttttgc attatagcgg ataatatgcg gtaaaagaat cgcatttgtc
    41341 cgtccatgag ggatcccgta ttccccgccg attttatgtg cgactgagtg acaaatacct
    41401 aggaatgcgt tagcaaacgc cataccagcc attgtagaag cgttgtgcat tttttcacgt
    41461 gattccatat caggtgtttt tactgatttt tctaaatagt caaagactaa cttgattgct
    41521 tgtaggctca atccacgtgt ataatctgaa gccatgactg aaacatagga ttcgattgca
    41581 tgtgttaaca catccatccc ggtatctgct gtgacagatg ctggaactga catgacgaat
    41641 tgaggatcga cgattgcgac atctggcgtc aatgcataat ctgctaacgg atatttcaca
    41701 tgtgtttcac tgtcagtgat gaccgcaaat ggcgttactt cagaaccagt ccctgatgtt
    41761 gtcgggatac atacgaattg tgttttttct ggtttgtcga tcttatatgt ccgtttacgg
    41821 atatccaaga atttttgttt tgcaccaaag aaagatgtgt ctgggtgttc atagaacatc
    41881 cacattccct tagctgcgtc cattgcagaa ccgcctccaa gagcgattac tgtatctggc
    41941 ttgaagtctg ccatcagttt cgttcctgcg tatacggtat ttgtcgatgg gttcggttca
    42001 acatctgaga agacttcgat cttcacatca tttttacgtc gtgccaatac ttcacgaact
    42061 gtatcgcagt aaccgaattg gaccatacca gggtcacaaa cgatcatgac acgttcaacg
    42121 ttttccattt tctctaagta caatagagag ttcttttcaa agaagatttt tggcggtaat
    42181 ttgaaccatt gcatgttatt tctccgtttc gctacagttt tgacattgat taagtttaca
    42241 gcagagacgt tacgagaaac agagttctta ccataagaac cgcatcccaa agtcaatgac
    42301 ggaatcattt cgttatagat atcaccgatg ccgccttctg cagatggtgt attcactaaa
    42361 atacgacaag ctttcattcg aagaccgaat ttgacatgca actcttcgtt ttctgaatgg
    42421 ataactgctg tatgtcctaa tcctccaaga ttcaacatac cttcacacaa atcaaacgca
    42481 tggtccgtgt tgttagcttt gatcatggca agaactggag aaagtttttc tcttgatagc
    42541 ggataatctg ggcctacgcc ttccaattca gcaatcagca ttttcgttcc ttttggtaca
    42601 ctgattcctg ccaattttgc gatttccatc gcagaatgtc caacgattga tggattgacc
    42661 gcatattttc cttcgttcat cactgcatct tctaattttt gcaattcatc tggttttacg
    42721 atataaactt ggtgtgcttg gaattctgct tttactgctg catagatttc tttatccacg
    42781 atcacagctt gttcagaagc acaaatcatt ccattatcaa atgttttcga aacgatcaaa
    42841 tcgttcactg cacgtttaat ttttgctgtt ttttcaatat aagctggtac gttacctgga
    42901 cctacaccta aagctggttt tcctgtagag taagcagact tgaccattcc agctccacct
    42961 gtcgctaaga cgatcgcgat acctggatgg ttcattagca tagaagtcgc ttcgatcgaa
    43021 ggatgttcga tccattggat acaattttca ggagctccgg cagcgatagc agcatcacgt
    43081 accactcgtg ctgcttctgc agaagatttt tgggcacttg gatggaaagc aaaaacgatt
    43141 ggatttcttg ttttcaacgc gatcattgat ttgaaaatcg ttgtggaagt cggattcgtt
    43201 gttggagtta ctccgcaaac cacaccgact ggttcagcaa tttcaatcaa ccctttttgg
    43261 acatcttcat tgatcacacc aactgtttta tcatgtttga tattatgcca aatatattcg
    43321 gacgcataca tatttttgat tgctttatct tcgtaaacac cgcggcctgt ttcctctaca
    43381 gccatcttcg ctaatggcat atgttgatcc aaagctgcca ttgccatttc atgcacgata
    43441 tggtctactt tttcttgatc aaagctttcc atttctttca atgctgcatt tgctttttct
    43501 gccaaatcat caatcattgc ttgtacgtca attgtcttcg ttttttcttt ttctattact
    43561 ttagccatca ttatcctcct aatgggtcat ggttatttgt taaataattc acatgtatat
    43621 catacaatat ttatttttct atgtaaacac ttttttgtga tttttttcac agttattttt
    43681 aaatataaaa ttgctttatt tacaggtgtt tgtatagaaa aatatataaa gttatttatt
    43741 attatttata tgacacaccc gattattcaa tattgagcaa tatatcccat gctcttatct
    43801 ctttcttttt tgaataaaaa atgaggtagg acatctttct gccctacctc gtctttaaat
    43861 aagctttgat acttattttt cttccttctc ttctgtctct tccagcgttt ctgttgtttc
    43921 agtttttact tcaactgtct cagctggttc ttctgttgtt tcaacagtag tcgttgcatc
    43981 atttgttacg acagtccctg gtttgaccgt tttgattgct gcacgatcgt actcaaggaa
    44041 gatcccttcg cagtctaaaa caactgtccg tttgtcattg tcgatttctg aaacaactcc
    44101 atgtaatccg ccgatcgtta cgactgaatc acctggtttc atgctatcta acaagttttg
    44161 acgttcttgc tgttgtttct tttgcgaacg tgacataaaa aaccacattg ctaatagcgc
    44221 gataaacatc acaagcattg gtaatgttcc catttttttc acctcactaa ttctgtatct
    44281 acaaaaaaca ctttagcaga aaaatgctga taacactagt tttttactta atttttaaaa
    44341 gattttcctt tagaagcttt ttgcgttttc tttattgaac ccgtattctt caaaaaaggc
    44401 ttctctaaat tcaagcaaat tatcatccat gattgcttga cgtacttgtt tcattagatt
    44461 caacaagaag tataaattgt ggtaagaagt caaacgaatc ccaaatgttt catcacattt
    44521 gatcaaatgg cggatatagg cacgtgtata gtttttacat gtataacaat cacatttctc
    44581 atcaattgga cggaaatcat gggcatattt cgcatttttc actactagac ggccttgaga
    44641 agtcatacat gtgccatttc gagcgattcg agtaggcaag acacagtcaa acatgtctac
    44701 tccacggata acaccatcga tcaatgaatc agcagcaccg acacccatca agtaacgtgg
    44761 tttgttttcg gggatcaacg gtgtagtgaa ttctaataca cgattcattt ctgatttagg
    44821 ttccccgaca gataacccgc cgattgagta accagggaaa tccatcccga ctagatcttt
    44881 cgcgctttga cgacgaagat cttcaaaccc tgctccttgg atgattccaa ataatccttg
    44941 acggtctgga ttagcatgag ctttcaatcc tcgttctgcc catcgagacg tacgttctac
    45001 tgattttttc acgtagtcgt aactttcatc gaatggtgga cattcgtcaa aactcatcat
    45061 gatatcagag cccaatttat tttggatgtt gattgctttt tctggtgata aaaacatacg
    45121 cgaaccgttc aagtgatttt tgaaatgcac gccttcttct tcgatattcc gcatatcact
    45181 taatgaaaaa acttgaaagc cgcctgaatc tgttaaaatc ggttgatccc agttcataaa
    45241 tttatgcagt ccgccagctt cttctactaa gtcttcacca gggcgtagcc ataaatgata
    45301 tgtattactt aaaataacgc cagcacccat ttctttcaac tcttctgggg acattgtttt
    45361 tactgtagct aatgttccta ctggcatgaa cattggtgtg gggaaagttc cgtgtggcgt
    45421 gatcaattcc cctaaacgcg cgccagtatg tttttctttc ttgattaaac gatagcgaat
    45481 ggcaggttgc gtcattcatt tccctacttt ctatataaaa tatcttgaca actcccacca
    45541 tcataatcgt ttcaagtgct ttttgcaagt tccctcggct tccttctact ttatttaata
    45601 ttcttttttt tatccttttt ttatgaataa caaaaaaaag aaaaacatta tgacagaaat
    45661 attttttgat acatggtata ttggtgttat taaagaaaag gagggaaaaa tcatgcaatc
    45721 ttctgcagaa ttaaaacgcc aagcaaaaga gagtctaaaa ggacgttggg gacaagctgt
    45781 tttactaaat ctaatcccta cattgattgg tattgctact attcttctta ttatgattcc
    45841 tattatcttg tttgccacca ccatatatga tggatcagcg agcgtctcag aagcgacaac
    45901 ttcaggaggc ggtagttcag gaggcggtgg cggaattatt tccagcatca ttagcgcttt
    45961 gttcatgagc ggtatttctt ggacttatct tgatatttta cgtggacaaa aagatcagat
    46021 cgaaccattc aaagatgcat ttcgtggatt caaaggtttg tttatcggcg gagtgatcag
    46081 cttagctgtg ctgatctcga tctttacaac attatggggt ttgctattag ttattcctgg
    46141 aatcattaaa agctattctt attctcaaag ctattttatt tactacgata tcgtccaaga
    46201 aacaggacaa acacctaaag tactggatac gatcactgca agtcgaaaat tgatggatgg
    46261 ttataaagga caacttttct ggttagatct ttcatttatc ggctggcata tcttagcatt
    46321 agcaactgct ggtattggtt atctatggct cagcccatac atttctgcaa caaaagcagc
    46381 attttatgaa caattgccaa aagatattta aaagagagtg tgacttgtga ccgagggggt
    46441 ggcaggagaa caccgtttat cgagaggcag taaaagaaac attcagccca ttagcaaaaa
    46501 ggaggtgtga caacattcat gtcacacctc ctttttgtat agttccagta aaaagaaaat
    46561 caacttagaa acagttaatc attcctcttc ttctgcttcc ggtaatcgat ggaacttgat
    46621 cagttcattc accgcgattg gtacgataga taaaatccct accaagaacc agtgattcaa
    46681 actgatgtgt actaggccga atagttcttg cgtaaatggc agcaaagcaa cagccgttgt
    46741 aatagctaat gccagtaacg ccatttctac caaagcttta ttggtcgcta aattgacttt
    46801 gaagatcgat tggctgctgc gtacattgaa cacatgcaga atcgatgaat aagctaagat
    46861 caagaatgca acagtttgac cgacatgctg acttgcgtct acccatgggc tgatagtatc
    46921 gacataacta cctaaataat aaccaaacaa ggttacgatg gtgaagaccc ctgcatttat
    46981 ggcaattttt tgcaataaac ctcgagcaaa gatcccttca tttttcggaa tgggtggctg
    47041 atccatgatg ccgtgttccg ctggctctct tcctaaagca aatcctggaa gtccatcagc
    47101 aactacattg acaaacagta gttgcacagc tgtaaatggt gctccccatc ctaacagcat
    47161 cgcaatcaaa acaataaaga tctccgaaat attacagctt agcaaaaagt tgatagcttt
    47221 acgaatattc tgataaaccg aacgtccttg actgacagcg tctacgatcg tcgcaaagtt
    47281 gtcatccgtc aaaatcatat ctgcggcact ttgcgccaca tctgttcctg tgatccccat
    47341 ggcacaccca acgttacttg ctttcaacgc tggtgcatca ttcacaccat ccccagtcat
    47401 cgctacgact gcacccgtac gttgccaaga tttgacgatc cggatcttgt cttctggcgt
    47461 tacccgagca tagacagaga gagctttgac acgcgcatct aattcttcgt ctgataattg
    47521 atgcagttct gatcctgaaa gtgcttctga cggatcattc aagataccta attctttcgc
    47581 tatggcactg gcagtcacca catgatctcc agtgatcatg actgttttga tgccagcctt
    47641 tttcgctcgc ttgattgctc ctttactttc tggacgtggt ggatcgatca ttccgatcag
    47701 accaatcaaa cgtaagtctt tttccagtgc ttcagaagaa atatcttgcg gttcttcgtc
    47761 ataagtagca taaccaacag caatcactct cagtgcccgt ttaccaaagc gatcattaac
    47821 gatcgccgct tgttctacat cgcctgaact aaagcgcgga gcaagaacat cgaatgctcc
    47881 tttggtgatt gagatgtatt tttcgcccat ttggtgaact gttgtcatca tttttcgttc
    47941 agaatcaaaa ggaagctcgt ttactcgtgg atatttttct tctaattctg cctttgtatg
    48001 ataattctct tcaacagccc ttacgatggc tacttctgtt ggattacctt tgataacaag
    48061 gtcgtcatct tcttgctcga ccgtcacatc tgtacatagt gcagccattt tcaatatttc
    48121 catcgcgctg ttcgtcattg aatcttcgat attcgttact tcatcttctt tgctccatac
    48181 ccggcggacg cgcatttcat tttgtgtcag cgttcctgtt ttgtctgagc agataacatt
    48241 agcggttcct agcgtttcaa ctgctggcaa ctgtcggatg atcgcatgtt tcctcgccat
    48301 cttctgcaca ccgtatgcaa gtgtcaacgt aacaataaca gtcaaggttt ccggtacagc
    48361 tgcaacagcc aaggaaatcg aagtcatgaa catctcaagg agtggttctc cttgcagttc
    48421 accaatcaca aatactaaag ccgcagccgc taaagcgatc atactgattc gtttgcctag
    48481 ctgattcaat cggacctgta aaggtgtttt ttgcatagta ttttcgttca aaagatccgc
    48541 gatcttaccc atttctgtag ccatgccaat ggcagtgacg atcgctttcc cacgacctgc
    48601 agcaaccgta catcctttaa ataccatatt aagttggtca cctaatgact catcttcttc
    48661 agcaataaat gctgcatctt tttcaactgc ttcactttct ccagtcaacg ccgattcttc
    48721 tacacgtaat tgtgatgctt cgatcaaacg ggcatcggca gaaatagcat caccggactc
    48781 taaaacaaga atatcaccca ctaccagttg ctctgactca acagtggtca ctttgccgtc
    48841 tcgtatgaca gttgccgttt gtttattcat atcttgcaag gattccagtg ctttttctgc
    48901 gtttccttct tggacaatcg ccaataccga gttgatcaca acgatagcga tgatcagcag
    48961 tccttcaaat aaatccccat gttctgtagc aaatgcggta taaaaggaaa tcaccgctgc
    49021 tacaagaagg atgatcgttg taaaatcgga caagcttcga aagaattttt tgatcatcga
    49081 ttctttcggc gcctcatcga atttattcaa tccctgcttt tttcgccgtt catccacttc
    49141 ttgtgaagac aacccagtat ctggatctgc ttctgttacc ttctttactt cttctattgt
    49201 ctgcttgtat tcttccatcc tattcctcct ttaaaatctt cgtacaaaaa aaggtactta
    49261 ttttactata acatcctttt tttatttact tcaaataaag ggcttatcga ttatttgtta
    49321 agaaagcgta aaatttaaag tgcttatatt tgcaaacgct accaaaggat gctattatat
    49381 agatgtaagg aaggaggata ccatcaaata gacagaagaa tttctcgata gaacagtgta
    49441 agcaaacaaa gttgttagaa gtacaggttt cacccagaca tgcgtgtaga gtacaaacct
    49501 ataaatagtg aatgcgtatg gatgtttgga tcacgaagta tccgaaacaa gaagtaatgc
    49561 gatacgtaac aattgaataa cgtaaacgtc tgaaaattga ataggaacaa gagatgtttc
    49621 aaatgttgaa gatgtaacga aaacaaaatt tttgtttaac atgaagaaat tcaacaccgt
    49681 gctttgcatg tatgatggaa agttacaatc atttctgttt atttgaatcc ttccgaggta
    49741 caagaaagcc gagcttatcg agagctcggc tttttctttg tcataaaatc tttgtaaagc
    49801 ttttttgtta ttcaaaacta gcggcttttc ataaccttat ttcacgaaca tcgcatctcc
    49861 aaaactaaag aaacgatagc gctcttcaat cgcatgctgg taagcagata aagtcaattc
    49921 tcttcctgca aaggcactaa ctaacatgac taaagtcgat tttggcaaat ggaaattagt
    49981 tgagaaagct tctaccactt tgaattcata gccaggcgta atgaaaatat cagtccatcc
    50041 gctgtctgct ttgatttctc cattaaattt cgttccaatc gtttctaatg ttcgaattga
    50101 agttgttccg acagccacga ttttcccgcc atttttacgt acttggttca atcgctcagc
    50161 cgcttcttcc gtcaaacggt agaattcact atgcatatgg tgttcttcaa ttttatctac
    50221 gctgacaggt cggaatgtac ctaaccctac atgtagtgtc agatagacta attcaacacc
    50281 ctttgcttcg atctcatcaa gtaattcttt cgtaaaatgc aatccagctg ttggcgctgc
    50341 agcagaacca ttttctttcg catagacagt ttgatagcga tctgggtctt ccagacgttc
    50401 tttgatatat ggaggcaatg gcatttctcc caatgattca agaatctcta gaaaaattcc
    50461 ttcatactca aagtcaatga tccgtccgcc gtgttccaat tcttctttca ctactgcttg
    50521 caatctgcca tcaccaaaag agattcttgt cccaactttg gcacgtttcg caggtttgat
    50581 caatgtctcc cacgtatctc cttgtgtatt cgttagaaga aggacttcta aatgcgcacc
    50641 agtatctggt ttttctccat ataaacgagc aggcagaact cgtgtattat tcataactag
    50701 cgcatcacca ggctgtaact cttcaatgat ttcatggaaa tgtttatctt ccatctctcc
    50761 agttttccga tccaaaacaa gtaaacgaga atgatcgcgg tcttttaatg gtgtttgtgc
    50821 gattaattct tccggcaagt caaaatcaaa atcttctgtt gttaacatat cgtcactcac
    50881 tttctatcat gtgcttcatc attctatcat gtttttcgtt ctgttggcaa aatcagcact
    50941 ttttcacttc tattttttgt tttcctaaat aaaaaaacta ccctatttgt attttttcat
    51001 tgttttaggc atactagtaa tagatagttc ttcattgaaa atagaaaaag aggtggcacc
    51061 atgattgaat ttcaaaatgt gtcaaaaatt tataaaggtg gaaaagtcgc tgtagaggac
    51121 gtcaatcttt catttgaaaa gggtgagttc atttgtttta tcggtacgag cggaagcgga
    51181 aaaacgacga cgatgcggat gatcaaccga atgactgatc caacacaagg gaaaattttg
    51241 attgatggaa aatccatcca agaaattgat ccagtggaat tgcgacgtca gatcggctat
    51301 gttatccaaa gtattggatt gatgcctcac atgacgatcc gtgaaaatat cactcttgtc
    51361 caaaaattgt tgaaagtcag tcaagaagaa cggaataaaa cagctgaaaa aatgattgat
    51421 cttgtggaat tgccccgtga gatgttagat cgctacccac atgaattatc tggtggtcag
    51481 cagcagcgta ttggagtcgt tcgtgccctt gcagcgaatc aagatatcat cttgatggac
    51541 gagccattcg gtgcgcttga tccaatcact cgtgattcct tgcaagacct tgtcaaagat
    51601 ttacaagagc gtttgggaaa aacgatcgta tttgtaaccc atgacatgga tgaagcgatt
    51661 aaactagcaa gccgtatcgc catcatgagt gaaggccgtg tgatccaatt tgatacacca
    51721 gaaaatattt tacgtcatcc tgcaaacgat ttcgtagaag agttgattgg agaagatcgc
    51781 ctactacaag ccaagccaaa tgcgacaaga gtcggcgaag ttatgctaaa tacagcaatc
    51841 acgattacac cggaaaaatc attacaagaa gcaatcaaac tgatgaggga aaaacgtgta
    51901 gatacgttgt tagttaccga taattcgaat gtattaaaag gatttatcga tgtagaaacg
    51961 ttgaataaaa aacgaggaaa agtatccagt gtcggcgaca ttttgaataa acatgttttt
    52021 tacgtaaaag aatccgccta tcttcgtgat accttgcaac gcattttaaa acgcgggctg
    52081 aaatacgtgc cggtcgttga tgaacagaac aaagtcgtag gtatcctgac tcgtgcatca
    52141 ttagtggata tcgtctacga tgtgatttgg ggagaagatc ccgcaactac tgatgttgca
    52201 gagtcagcta ctcctgaaga atctaaggag gtctgaccta tgcagcagtt ttttcatcag
    52261 cacggttcag aaattctctc aaaaggtttt gaacatcttt atatttcagg acttgctttg
    52321 atcattggta tcatcattgc tgtaccgctt ggtgtcttac tgacacgttt tccaaaagct
    52381 gccacgattg tgattggctt aaccagtgcc ttgcagacaa tcccttctct tgctttattg
    52441 gcattgatga tcccgctatt tggcgtaggt aaattacctg cgattatcgc actctttatt
    52501 tattcattat tgccgatttt acgtaatacg tacattggga tgaaaaatgt cgattggaat
    52561 tatcgggatg tggcaaaagg catggggatg actgagttcc aatccatttt ttccgttgaa
    52621 ttgcccattg ctatgccaac gatcatggct ggtattcgtt tagctgccgt ttacgtgatt
    52681 gcatgggcta cacttgcctc ttatatcggc gctggtggtt taggcgattt gatttttagt
    52741 ggactgaata attaccaacc agatctcatt ttggcaggta cgatccctgt aacaatttta
    52801 gcactattgg ctgattggct tctaggtctc ttggaacacc ggctgacacc gatcgcactt
    52861 agagaggaga atgaagaatg aaacgtatac taaaaatgac catggttctt ttctctcttc
    52921 ttatacttgc gagttgttcc ttccctggtc ttgccagcaa tacagatgaa gacaccattt
    52981 cgatcacagg tggaatcact tcagaagcac agatcttagc aagtctagtt gccggaatgg
    53041 ttgaacatta tacagataaa aataccgcaa tcatcaacaa tctggctact acaactatca
    53101 accatcaagc gatgatgaac ggagatgctt caatttcagc ggctcgctac acaggaacag
    53161 atttaacgac tacattgaac cttcctcctg aaaaagatcc gaaaaaagcg tttgctaccg
    53221 tgaaagatga atttgagaaa agatacggtc aaacgtggtt cccgtcctat agttttgaaa
    53281 atacgtatgt ctttcttgtt cgaaaagaca ccgcacaaaa ataccatcta tctaaagtca
    53341 gcgatctgaa aaatgtagcg gatgaattag tagctggtgt agatacttct tggatcaatc
    53401 gtaaaggaga cggttatgac ggcttccaag aaacttatgg cttctccttc aattcgatat
    53461 tacctatgca gattggactt gtttatgacg cagtcgaagc aggaaaaatg gatattgttc
    53521 ttggctactc tacggatgga cggatcgcca gttatgatct agtcatgttg gaagatgatc
    53581 gtcaattctt cccaccatat gatgctgctc cagttgtaga caacaagata ttagctgata
    53641 cgcctcattt aaaagaagcc ttaaataagt taggtcatac catcagtacg gaaaaaatgc
    53701 aggaattgaa ctacgaagca gataataatc tagtggaacc atcagtagta gcacaacgtt
    53761 tcttacaaga aaaccactat tttgaaggga agtgaagcaa ttggataaaa tgaatgtctt
    53821 tcaacaattt ttctattatt tccaggaaaa tggctcctat atctttgcac aatttatccg
    53881 tcacttcctg atttctatct atggtgtcct ctttgcagca gttgtcggga ttccggttgg
    53941 gatcatgatt tctaggagac gtaaattagc aaactgggtg attcgtttgg cgaatatcat
    54001 ccagacgatc ccttctctag ccatgatctc cattttaatc attggattag gcctgggagt
    54061 caatgtcgtg attgttactg tatttttgta ttccctctta ccgatcatca agaatacgta
    54121 taccgggatg atccaagtag acaaaaacat ccttgatgtc ggcaaaggca tggggatgac
    54181 tgctagacaa cgactattca tggtagagtt accactctct gtttctgtta tcatggcagg
    54241 cataagaaac gcgttagttg ttgccatcgg gataaccgcg atcggtgcat tcgtcggtgc
    54301 tggtggtctt ggagatatca ttatccgagg aaccaatgca acagagggca catcgattat
    54361 tttagcaggt gcattgccaa ctgcattaat ggcgatcatc acggactggc ttttaggtat
    54421 tttggaaaga cggctagatc cagccagccg tacatcacgc tgatgttatt gtaaaaaaca
    54481 aaagcttctg cgaccatttg ttggtcgcaa aggctttttt agttctgtca tttttaaggc
    54541 aataatccac tctgattctt ccctccttat gggcaaagag ttgcttttct tagctattta
    54601 tccattccgt atactccaac ttcatactgc caacgggttc atatctgcat ccaccgacta
    54661 agtttttttc ttatccgcta aggcattttg ccaatccatt ttcccatcac tcgtcatgga
    54721 attcatacca catgatctct aaatactcgt ctgcttgttc tttgaattgg gcatcaattc
    54781 ttacatcctt tggcgtggct ttcatttaag ccttttccat cagtcctcga ttgttcgatg
    54841 ccttcagctg catcatcaaa actggtgact gccgtatcgg taacttcgat catcttttat
    54901 acaatcggga acttgccatc ctcatccttg gctaaaaaca tatctagcca ttccagcttc
    54961 tcgccatggg aggtttgcgg ttcctaaaac cggtacacga ttcttatgga ctgcatccgt
    55021 cgcaactaga cttggcgata cgatgatcct tcaccagaag agcacccccg taaaccaatt
    55081 gatcgatata ttgccaataa gaaaagacat tggcgtaaaa gatatcgatc cctcgtgatg
    55141 cattgccgtt gatactgcta ttcatggccg aaagcgccac gactttaact tcttccgttt
    55201 gagtgacatt catgttcggc aatgtcgctt tggatacccg ctctgctaaa ggaacgacac
    55261 tggtattgta tttcgtatct gtatcttttc caaaagacca tgccaacgaa tcctctggga
    55321 accaataaga cgactccggt tgattgtcca ttgctttttt caacatactt ttggctgttt
    55381 ctcgataaac gacatttcca attgtcttcg cctcactttg gcgataatcg atggtcgttg
    55441 ccactgccaa cactaacaac gatgctccaa ttttactgat tttccttgtc acacttcttc
    55501 ctccttgttt tacataaacc cgtcaacatt ccattcctaa actcaaacaa tgacccttca
    55561 aaggtggaga tataggaaca aattaaagaa atcatgcaat aaatccaaga aggttggttt
    55621 tagaacaaaa aaagagtctc ctttttgggg agactctttg ttaactatct aaaaaggttg
    55681 gctcttctca cttcactcat aatgtgtcca ggcagaataa atttctacaa ctttattttc
    55741 ctcatcaact ttgtaaacca ctcgatgctg tctattcagc ctgcgtgagt atctgccttc
    55801 atgtgtaggt ctcagctttt caaaagactg cgtgggcata tatggatctt ccttcaatgt
    55861 ctgaatcact tcttcaaatt gtttctttaa attcgtttgc ttgatttttc ttaaatccac
    55921 tttcgcagag tttttgattg cgactgtata gttactcatc aaagagcttc ccaatcaata
    55981 tcatcgatat tcgtaaagct actgtcgtct ttttcgcggt ctcgtacttt atctaaagta
    56041 cctgtttgct caagaaaaag ggtttcttga atcgctctcc agtcttccag cccaatcaat
    56101 acagcattgt ttccactacg atcactaata atctcgattt cagtatgatt ttcatttacc
    56161 tctttcaata actgataaaa atttttacga gcagtgctag gattcatcgt tgtattagcc
    56221 attgtctctc ctcctttttc tgatataatt atagcgtact tgattaagta cgtcaaaaaa
    56281 atacaataaa gcacttaaat tcagcaaact tttcctcttt tttacataga gaaaaagacc
    56341 cctttttagg gaggatcttt gtccacgctc acttcttact cctttacgac tagcggtagc
    56401 caaacgtaaa gtaattggta acaacgtatc atctttagca aaggtcgaat ccaaagcctg
    56461 tgagtctatg caacaacacc aatacacgaa ggttcctcgt tgcagtgtga cttgattgat
    56521 atcttgaata acctgaggat acgcacgaaa gatttgtaac ggttattcaa aactgatttt
    56581 ggccgtcaag tcttctactg cctcaaaaat gattgcctct ttcgtctcct gtcattcatg
    56641 ttcactatcg atttgatact tgcttagacc gttgggtttg tgaatcacca attaaaaatg
    56701 gcactgagtt atggtaacaa aaaatggtca cttgacgagg ctgagattcc tacttatgaa
    56761 gacacatggc acttaagagt cgaggtaaag gaagaagctg aaaatatagg aggctgtaca
    56821 ttatttggca aaggattcgg aaattatgat caagacatca aaatcaaaat gttttacagc
    56881 taaataggaa gaataataac atttcatacg ctgttcccat ctttaatggc ttatagaggg
    56941 cacctttagc tgagaataag acaaaacaga ccctctagct tcaattaaga gctagagggt
    57001 ctgtttttga ttttaaaact tggtttattt cttcaaatgg tagctatagg tgctgacaac
    57061 gatattttca cgccaagaca atcgcaatct taaccgcaaa cttgtttggt tatggagaat
    57121 attctgccag cgtctgtttg gtacaaattg aggaatcaac acagtagttg tatagttttg
    57181 tttcgctgca tttttactta cgatatctac ataacggata attggatttt caatcgagcg
    57241 ataagaagag tggacgattg aaaaacggac atctgggaaa tgctttttaa attctgcttc
    57301 gatttctttt tctttttcga catcttcgtc tagcgaaaca tgcatcgcaa cgacataatc
    57361 accgatcgaa cgtgcgtaat tcaacgcacc gatatttacc cgtgtcacat tcccgactaa
    57421 tacaagaacg gtattcccgt cataatcatg tagttttgca tcattttcta aacgaagctg
    57481 ttctgctact tttttataat gatcatggat cttataaaaa atgaacataa cgattggcat
    57541 aatgatgaag aaaggccaaa tgtcccctaa ccgatagaca aacaaaatcg caatgattgc
    57601 atatgagatg aacgcacccg taatattggc aatcgatttg cttaaccatc tttttccttc
    57661 ttttttccat ttgacgacca tccctgtttg agataaagca aatggaatga acacgccgat
    57721 agagtataac ggaatcaagc gttctgttga gccatggaaa ataaacagca atacgatcga
    57781 acctagcgct agtgtgataa tcccattgga atagcctagt cgatccccac gatcttgata
    57841 catgtgaggc atgaatttat cttttgccag attgtatgca agaactggaa aagcagaaaa
    57901 accggtgtta gcagcaactg ctaaaatcag cgctgtagca aattgaagga cgtaatacaa
    57961 aataccatgt ccaaagacag ctttaccaat ttgagacaaa acagtgactt ctttttcagg
    58021 aacgatccca taccaatagt tgataaatgt gatccccacg aagaagaaac ctaagatcaa
    58081 tgccatcatc gtcaatgtag cagcggcatt ttttgctctt ggcttcttaa agaatggtac
    58141 agcattacta atcgcctcca ccccagttaa agaggaagaa ccagaagaaa atgctcgtaa
    58201 aatcaaagcg atagaaacac ccggcacagc cgctcctgga agtgcagtag cttgcaatgg
    58261 cacagcacct gtcacgatat tatataaacc aacaacgatc agtaacgaga tcacaaggat
    58321 aaatgtgtac accggaaata ataggaacga tgcagattcc ctcagcccac gaagattcag
    58381 catcatcagt agcaaaacga ttgtcacaga aatagcgact tgatgaccgt agagtgctgg
    58441 caccgctgat gtgatcgctt cagcacctgc tgagacagat actgctactg tcaacatgta
    58501 gtcgatcaat aaagagccac cggaaatcaa gccagcattc tttccaagat tctcactgct
    58561 gacgacatat gctcccccgc catgaggata agcatggatg atttgacgat atgatagcgt
    58621 taatgaaatc aataaaataa taacaaaagc ggcaatgggt agcgaatacc agatggctgc
    58681 agcagacaaa gcgactaaaa cgacaacgat ttgttccgta ccatatgcaa tagatgataa
    58741 cgcatcagac gacaataatg ccaaagcagc aaatcgggtt aatttgtgct catcattttc
    58801 agcagatttt aaaggcttac ctactaacaa cctttttaag taatccaatt tctaaactcc
    58861 tttacacaca attttacttc aagttttata gtcgaaaatt tatagtaaac aagatgttat
    58921 agtacgctca ctgaccttaa aagtcaataa actttaagaa aataattgga aaaaaacaga
    58981 aaaatatcaa gcgctttttc aaacgcttta atacagcaaa aatctaacat ttttttatgg
    59041 gctttttctt tgaattctat aataaaagga tagaacttga cttagaaaat caagttctat
    59101 cctttttgat atcttaactt ttggaagaga gatgtaaggc tgctttctac ccatcattct
    59161 tactactcga agcatagcgc agttgtcaca acctcttgat aaacggtgtt taaaagcttg
    59221 catctgcggt aataagccca accaaattaa aaacataaga agctgttttt atttggtcgt
    59281 tcttattact tgatgcagag cagctttttt acaacctctt ggtacacggt gttcaatcag
    59341 ctgaccctcg gtattagctc aaaaaaacgg caaaatatga ggaactattt ttccattttt
    59401 ttctctaata ctcaggtcaa aacactgatt tcacaacctc tttttttaat gaaaaatatg
    59461 gctctcatgc gccgcttctt tgaatttcgt cattttttct tcgatgaacg gatagattgc
    59521 cgttcctacg attccaaaga caacaaacaa accgatcatg atccagattg ctttcgtagc
    59581 atttggccaa taaattcctc ctgcagattc ccgtaacaag tttaccgcat gagtaaatgg
    59641 caagaacgga ttgatcattt ggaagaattt ccctgagact tggatcggat agttcccgcc
    59701 tccgccagag atcgacagta ctaagatgat aatagcgatc cctttaccga cattatcgaa
    59761 taatgcagcc aagacataga cgatcatcat gaacgctaag gcgatcaaga cagcaaatga
    59821 cacgctgtag accggatttt ggacatctac tcctagtaag aaaatattcc ctaatgtaac
    59881 gatcaagctt tgcgcaatcg ccattgtcaa aaatgtcagc atacgagcaa cgaattgttc
    59941 tcgtttcgta aaattgtttc ggtctttctt tcctaaatag tattctgtcg tagcaacact
    60001 tgaaagaaga acagcgccga cccacagaca tagtgcagta taaaacgggg tgctagctga
    60061 accgttattt gcgattggat aaagcgcatt ggtttgtagc tcaacaggtt gtgtaaagaa
    60121 gtcactttct tttgttgcgt ctagtttcaa taatttgatg acttcgccta gatcgacttc
    60181 ttgttcgcct tttcggatcg cgtctgctgc tttttggata ccagctttga tatttggcca
    60241 gtcattgttg atcaagtccg cagcagcgtt cacagctgtt tcgacttctg gcattttttc
    60301 atttactgtt gtcaatgtac cggtgatttc attttttagt gctggccaat cattttggat
    60361 aaaatcagcg gccaatccta atttttgctg aatgatcggt aattcattgt tgtataggtc
    60421 tgccccttca ttgatgccat tgacgatggt atccatattt ccattcagca ttgtattggc
    60481 atcatggatt tcttgtccaa ttgcaggcat ttctttttga tatttttcta aaattgccac
    60541 tgcattcgtt acagttgctt tcgttgagct gagaagcgaa tcaaagtcga tctggtccgc
    60601 tttgctcagt gcgccttgtg cagtcccaat cgtatcgatg acttggtcta gtagagaagt
    60661 gacagtggaa ctgatttgac ctgtattgat accagcaatg atgccattga tattattaac
    60721 aacggcatca atttgatcta gcaattcatc aatagccttc gtgtcttcat tttgaacagc
    60781 tgtgttcaaa gcagataggc ggttttgcag attgcttagc aagggtttta attgatttag
    60841 ctgatcaata attggctgta atttcgtatt tccagcactt gtttgcaatt tagtcaggaa
    60901 ctcgaccagt ttatcgattg cattttgttg ttgagatatt ccgtcaataa agccgttcaa
    60961 tacattgctg atgtttttct tttcatcatc agtcagctta ccatcttcaa tagctgttct
    61021 tacagtatct attaacgaac ctgtcgttgt tgccacttgt ccaattgact tcaatgtaac
    61081 atctacactg tttgtgatgc ttggtatcgc atctttcagc tgagaggcac ctgattttgt
    61141 ttggtttgct agatcacttg cctgattttc taaatttttc acatctggca agatatcttg
    61201 tacttgttgg atgatcgtca agccttgttt tgcttcatcg attccttggt tcattgtctc
    61261 ttggatcgaa gcaaaatcgc cgtcgatctc tgctagttgc ttaccggcat tttggatctc
    61321 tgggattttt tcttgcaaat caaggatgat ttttgcttga tctttcaact caggcatttt
    61381 gtcattcaat gcaacgactt tttcacccat ctcatctact ttagggatgt aatccacgaa
    61441 ttcatttgct ttattcagtt tttccttgat ttcaggtagt tgactttgta attcgaggac
    61501 ttgttttgtg tagccgtcga tcgtgtccaa attttcatct gttgataaaa tcatatcttt
    61561 aactttattg atacttacta ggttcgtatc gatgtcgtaa cctatctcat tgaatacttt
    61621 caataaagtc gaactggctg ttttgataaa ttcatttgtg atttgcgatt ggatcgaact
    61681 tgctccttta tcggtgattt tcggtgcaat cgcattgatt ttttcattta ccgtatattc
    61741 gatttttggt ttcttgatat caccactagt aaaactcagc agatcttctg agaaatcctt
    61801 tggcaagtaa atacctgcgt aatactttcc ggaacggact ccgtcttcta attgttcttt
    61861 tgaatcaacg aattgccatc ctaattgttt atttttatga agcgattcga tgacttgctc
    61921 cccaatggcc acttctttac cttgaaactc tgctggcttg tctgcactgt aaacagcaat
    61981 tggcagctct ccagtatttc catatggatc ccataatgct ttgatgttaa accacgcata
    62041 tagcgaaggg atgatcatga tcgcgatgat cagaagtgtt gcaatcgggt ttttgaaaat
    62101 ccgtttccag tcaagcaaat ataatcgaag cgtatttttg attgactgca tagttctccc
    62161 ccttcttctt ttttcagctg aattacttta ccatgtattt catacttttt tcaatcggct
    62221 tttttcaaaa aagtcgaatt tttggacata tcacggcaat tgtctcattg taatctctta
    62281 catattgaga aataattaag gattacagcc tttactttat catgaaataa aagggaaaga
    62341 taattttatg ccaaagtttt tatctattat acgtatacgc aaaaaagcta aaacattttt
    62401 tgtctttgcc cctacaaaaa tgtttcagct tttttcgttt tttattcctg tatttcttat
    62461 ttttcgaatg acaggatgat tttcccagca ggaggatgtc cttcaactag ctgatgtgct
    62521 tggatgacat gcttaagtga agcagacaga ttcattgaaa taaaaacatg aaaggctcct
    62581 ttttggtagg ctttgattat gccagcaaag gcttctgcat ctagatattc ctttcttgga
    62641 acaaacgatt cataaaagcc ttcctttttt tgccgcaaat ctagatctgg gaggtcattt
    62701 aatgcaacat acctgccgcc tggtttcatg atctggatgc cggtttctcc tttgatactt
    62761 cctttcgtcg catcgattac aaggtctgcc tgatcagcaa attgcagacc tggatttgtt
    62821 ttatcataag cagcaaatgc tgaagctcct aattttttta ccttttcctc atttttactg
    62881 gatgcactgg ttaagattcg gattcccttt tcatggagaa gctggatcag acttgacccg
    62941 accgcacctg atgctcctag tatcattaca gtatctgtcg gctggatttc cgtcaaatgg
    63001 ttgattagat tataagccgt aattcctggc gtgaccattc cggctgcttc ttcccaactc
    63061 attttatctg gaatttttgc tacttttgct gatggcaaca cgacttcttc tccgtaagtc
    63121 ccgccgactg catggacagc tactcgatca cctacatgaa cagttgtgac atctgaacca
    63181 atctctgtca caataccagc gccatcatta cctggtacat aagggaattt caatgttcgt
    63241 atctctttca tttctcctaa acgcaaggca acatcataag gattcacact gaatgctttt
    63301 atttctacac gaacatgtcc agaaccgact tctctgggat gagcatcgat ttcttcaaaa
    63361 acatcttgtg cttctccgta accgttaatt gcaaatcttc gcatggtcac catctccctt
    63421 tttctttaag tttacgttta tgcctttatt ttgacaaaaa aaatgtcttt tcgttttggc
    63481 gcatgattca aaacaaaata gttgtctttt ttcgcgtaac gtgttaaatt atttatctaa
    63541 aagcgtaaag attacgattt acgctaataa aaaataattg gaggaatttg ttgatggcta
    63601 aaaaatcaaa gattgccaaa gcaaaaaaac agcaagaaac gattgaacgc tatgctgctt
    63661 tacgccagga attaaaagcg caaaaagatt acgaaggctt gcgtaaactt cctttagatg
    63721 ctcgtccaga acgattgaaa aatcgtgatt taatcgatgg acgccctcgc ggatacatgc
    63781 gtaaattcgg gatgtcccgt ataaaattcc gtgaattagc acataaaggt ttgattccag
    63841 gagtaaaaaa agccagctgg taatccaagt ctggctgtaa tgtaaaggag gagggcgcat
    63901 ggaccactcc ttggatcatc aaaaaagata cgttcgcttc ttctagcaga aatgctggta
    63961 ctagaagcag acgtatcttt ttttacgcac agctggtcct tttttatatg taaaggctgc
    64021 atggttactt cgctatattt atttagtaac aggagtcagt gcttcgatac ccacactaat
    64081 tttcaatgct cggtcaactt ctgccataat gggtcgatcc aaatggcaga ccttttcttt
    64141 caatcttgat ttatcgatcg ttctgatctg ctccaacagg ataacggagt ctctttctat
    64201 tcctgttcca gtagctttga tcccaatgtg agtcggaagc ttaggtttag ccatttttgc
    64261 cgttatggcc gcaacaatga tcgtcgggct aaaatggtta cctagattat tttgaataac
    64321 caaaactggg cgtgttccgc cttgctccga tcccacgact ggagaaagat cagcaaaata
    64381 aatatctcct ctttttacca taggatcctc cttattcttg atattctctt ggtatccgct
    64441 gtcctaatcc gcaagccact tcatagtgga tcgtacctaa ttgatctgct atatcctgca
    64501 tagtgatttc tttgtctgca tttttgccga taagcgtcac ttttgttccg acaggaaatt
    64561 cttgaggcaa tcggatcatc agttgatcca tacatacacg cccaatcgtt tcacagtagt
    64621 tcccttctac caatagagaa aaaccctgca tctttcgtgg ccagccatct gcataaccga
    64681 tcggtatcgt tccgatccac tctgcttcag gagtgatata tgtttctcca tagccgattc
    64741 cttcacctgc tgggagtttt ttgacttgaa tcaattcaga aaccagctca agtgctggct
    64801 gcaatggata aacttccggt agtgcgtgcc cagagggatt aagtccgtac attgctactc
    64861 cataacgaat catattgccg attgtttcat catgccataa agccgttgca ctattgctga
    64921 catgtacata tcgaggaagt tcgggaagtt ttttcagcac ttctataaag cgttcttttt
    64981 gcagattcca atatgtatca tctgcctgat ctgctgtaga aaaatgggta aataaacctt
    65041 cccattctaa tacacgactt tctttgatga atgcagctgc ctcttttact tcttcaggtg
    65101 tacaaaatcc gatacgaccc atcccagtgt ctgcttttag atgaatcgaa agaggcgtct
    65161 ctagcttact tttctctaaa acagcagctg ctgcttgcaa ccattcccgt gtacctgcag
    65221 ttactgataa atcatgagca acagctacag tcagtgcgtc gtaaggaacc atattcaaga
    65281 taaggatggg ctgagtaaat ccagcttctc tcaactcgac tccttcatct aaatttgaaa
    65341 cacaaaagcc cgaagctcca cctgcaactg ctgcctcagc tgtttcaata gctccatgac
    65401 cgtatccgtt cgcttttact actgcaaaca attcttttcc ttgcggaagt cttgcaactt
    65461 catttgctac attttcagtt atagcttttt tatgtatcac tgctttcgtt gggcggtgcc
    65521 aagcgacaac catcgttttt ccttctttct agtcttccaa aataatttgt gcaaaagctg
    65581 tttcatttgt atgagtaata ctgacccata cattgccttc atgaggtgaa cgcgtcacaa
    65641 caggctgacc attttcattt tttaaaatct cgacatcttg aaaggtaact tttccgatcc
    65701 cagttcccca agctttagag aaagcctctt tgcaagcgta acgcccgcct aaaaattcta
    65761 cttggcgatg aaaaggcaag gactggaata gtttcatttc atcagaggtc aagattcgtg
    65821 caatgaattt tggtttttct tcgatcagcc gagtgatcct aggaagttcg actgcatcga
    65881 tcccaattcc ttttatcata tgcttttctc ttttcaataa atttagaaca ctctcattct
    65941 accaaattat aaccattttg ccacaaataa gtccacaaat aacaaaaatg aaagtttctc
    66001 ttaaaaaaga gaaactttca ttttatgttt aatcgttatt tgaacggatt acaaatccgc
    66061 gttttttatc attgtgacgt ttaccgccat ctttttggct gttattattt ttgctataac
    66121 cgccttttga tttgtttcca cgataattac cgccgtcacg acgattacgg ttgtttccgc
    66181 caccacgttt gccattttta ttgtatcctt ttttctgcat tggcaatggg cgttctggtg
    66241 tgatcttcac tggcactgca tcagctggat cttttgctgt cgtttttagc aaaagtgcaa
    66301 ctaaatcttg tgcagaatat tcttctaata atttatctgc tgtttgcagg tatttatcta
    66361 gaccattttc tgcaagtttt gtttcgattt gttcaactgc agcacctaat tgacctttga
    66421 atgcttcttt ttcggttggt ggacgtaaag tcgtcatccg ttttttcgtc aagttttcaa
    66481 tcacatgcaa gtagtccatt tcatttggtg taacgaaagt cacagacata ccgccttttc
    66541 cggcacggcc tgtacgtccg atacggtgaa cgtagctttc tggatcttga gggatatcat
    66601 agttgtacac atgagtgaca cctgaaatat ctaatccacg tgcagcaacg tctgtcgcta
    66661 caaggatatc taaatgaccg ctcttaaatg aacgcaatac gctcattcgt ttttgttgag
    66721 acaaatcgcc atggattcct tctgcacggt aaccgcgtgc ttctaatccg cgtgccaatt
    66781 cgtctacacg gcgttttgta cgtccgaaga cgattgttaa ttcaggtgtt tgaacatcaa
    66841 acaagcgagt catgatatcg aatttttcgt attcttttgc gcggacatag tattgatcga
    66901 tcaagtcagc tgtcatttct ttcgctttga tcttcacatg atgtggattt ttcatgaatt
    66961 taacgccaat attcttgata gctggcggca tcgttgctga gaaaagtaat gtttgtcttt
    67021 gatcaggaac ttgtgaaatg attttttcga tatcttccaa gaagcccata ttcaacattt
    67081 catctgcttc atccaaaact aatgtttgaa cggttccaag tttcaatgtg tggcggttaa
    67141 tgtggtcaag catacgtcct ggtgtaccca caacgatatg tggacgatct ttcaagccac
    67201 ggatctgacg gccaatatct gctccgccgt aaacggcttg tacacgtact tttttgtcgc
    67261 gccctaaacg atataattct tcttgtgttt ggatagctaa ttcacgtgtt ggtgcgataa
    67321 ctaaaccttg taattcgtga cgatctggat cgattttttc taacattggt aatccaaatg
    67381 cagctgtttt ccctgtacct gtctgtgctt gtccaataac gtcttttcca gctaatgcta
    67441 gtggaatcgt ttctgcttgg ataggcgttg cttcttcaaa accagcgcgt tcgactgatt
    67501 tcaacaattc tggtgataat tctagttctt taaatttcaa atgaatcctc ctatatggtt
    67561 gttaactgag gatgtagctt ttttgctacc ccgtcgattt gttcggtcaa agtgtattgt
    67621 ttctttttga cagtggccac gcacgttttt atccattctt agcccctgtg gcaccaccga
    67681 aaaatcactt tgcgaagttt aggcattaga aaagccaaac gggtcgcgtt cagctttatc
    67741 attattatga catctggctt caacaagttg tttctatggc aaaaccagtc caatttctct
    67801 tcatctttcg gcaataggtt attctaacat agtttttcgt tttctgcaag tttacagatt
    67861 tttatttcat ttgctgaagt tgttctacca cttcaaataa gcccatgctg ttgctgcctt
    67921 ttagcataat actatctgtt gcttcaagat tttgtttgat agcatcaatc aatttattct
    67981 tttctttttc aaaatagaac acaggtagtt gggggtattt ttggttcaat tcttctttta
    68041 gtgcatgcat ttgttcccca taaaggaaaa tcatggcgaa tttctcagga tcgatatgtt
    68101 cactcatttg cgcatgcata tttaaagact ctttccctaa ttccagcata tctgctaaca
    68161 cagcgattct gcgtcctttt gttggcagat ttttaaaagt atctaatacc agtcccatgg
    68221 ctgttggatt tgcattgtag acatcgctca aaatagctgc accatttcct gccgttagcc
    68281 attcggttct gttttgagtg atagaaacat gggcgagccc ttggcgtatc tcaggtatgg
    68341 acagtccaaa gaagcgcccg atcgtatacg caatcaaagc attcgttaca ttataacttc
    68401 caggcagcgg gatcgtaaat gtttctcctt ctactacaaa atcggtttgt gcttttcctt
    68461 ttgctgtcac ttccgcatga acatcgccat ttccaatacc gaatgttgtg actgtttgta
    68521 ctaatgttgc cgttaaaggt gtcagcaacg gttcatctgc gggcacaacg agtaatccgt
    68581 ctgatacaag tccgtcagtg atttccattt tggctttagc gattccttct cgcgacccaa
    68641 gattttctat gtgtgcttca ccgatcattg tgattgctgc agcttttggt tgagccataa
    68701 gtgaaagttc cgtgatttca ttggcgtgat ccatgcccat ttccaaaacg atcttttctg
    68761 tatcttgggg catgtgcaaa atcgtgtaag gaagaccaat attattgttg taatttcctt
    68821 gcgtcttata tgttttgtat ttttcagaca agacagacgc ggttagatct ttcgtggtgg
    68881 ttttaccatt gcttcctgta attgcaacga cttctgcgcc tactttttcc aagtaatagg
    68941 ttgccaattg ctgcatggct ttcaaaggat ctgctacagg aataactgga aaattttttg
    69001 gagcttgttc aacaggcaag ctccaaaatg aagcagatgc tccgtttgtg atcgcttgct
    69061 ggataaattc atgtccatct cgcgtaccag caagaggaac gaataaactt ccttcggtta
    69121 tcttccggct gtcaaattcg acattggtaa tctttgtcag tgcagagcat tcgctgccca
    69181 cggcttgtgc aatttcttgt attgttagat tcattgagat ctctcctaaa aaaggttgtg
    69241 aaaaaagcgt ttggcctaaa cggcgggttc gcatgactct cacttccaag taaatttctc
    69301 tattcgtatt tagaagctag aatgaacgcg gttacgcaat cactccagcc tcttctttat
    69361 ttctctttat tcattttttt caaaaaaaga ttgacgctga tggtatcgat tcattcctaa
    69421 ctggatcagt tcttcaatca aatcaccgta tttcaagccc atattttccc ataagagtgg
    69481 gtacatactg aactccgtaa atcctggcat agagtttaat tcattcagga ataattcatt
    69541 tttatttgtc aaaaagaaat cgcaccggct caatccgctt ccacctaaca tcgtgtaagc
    69601 taacttcgcg tactcttgcg ctttttgata aacttcttct ggcacttcgg ctggaatctg
    69661 catttcgatt ttattattga tatattttgc ttcataatca tagaatgcta cgtcttttac
    69721 gacttcacca ggcaaagtcg tccgaacgtc ttcatttcct aatacagcaa cttcgatttc
    69781 gcgcgcttca attccttgtt caacgattgc tcgagaatca tactgatagg ctgttgctaa
    69841 agcattttgc agctcttctc ggttttctgc ttttgtaatg ccgacactag aacccatatt
    69901 cgccggtttg acaaacatcg gataaagcaa agaaccttca cattgatcaa atactttttt
    69961 aggattttct ttccattgat tcttaagtac tggtacataa ggaacttgcg gcacaccagc
    70021 agcttgtaaa atatacttgg tcatgatttt atccatggca catgcactgg tcaatacgcc
    70081 tgcgccgaca taaggcatat tcaatgtctc taagaagcct tggatcgttc catcttcccc
    70141 gtttggccca tgtaaaactg gaaaaacgat ggctccttct tctttgattt cgcccggatt
    70201 gatcactttt cctgtaaagc cttcctctgt ctgtccactt gggtcccatg aaagatgcaa
    70261 gacatctttg ctggcaggtt tttctgttag taatggacct ttgacccatt gtccttcttt
    70321 tgtaataaat acgagttgaa cttggtaata attataataa atggcattta aaactgaaaa
    70381 tgcggaaaga atggacactt catgctctgc gctgcgtccg ccatatagta aagtaatctt
    70441 caaaagattg tcctcctgta ttctaaatcg ttcagtgatt tactctcata ttttagcaca
    70501 aaacaaaaat aaacgaataa cttatttata aaaaaacgag ccagcttcta aaagaacgag
    70561 cgtcatttat tttttgtcag ctagattatt tgtcccgttt tttataaaaa gttatgataa
    70621 agaaaaggag ggatgatgat ggcgcaaaca aatccacgca gccgcttggc agaaatcatt
    70681 cgagtgttca tcaattacaa tgtagtgcca aactttgtac agcaaaaaaa tcccgaacag
    70741 gtaaaaaaag cctttgaaga actaggcccc accttcatca agataggaca gatgctttct
    70801 gttcgagaag atttgctttc ttctgccttc actcaaacat tcaaaacatt acaagatagt
    70861 gtacctagcg acacattttc aacggtcaaa aagacgatcg aaacagaact ttctctttca
    70921 ttatcagata tattcgatga tttttcaaaa tcgccttttg cctctgcttc tatggggcag
    70981 gctcatcgtg ccaagctgaa gaacggtgac gcggtagtcg ttaagatcca acaccctaac
    71041 atcgccgaag agatccgact tgatcttcaa ctatttgaac gagcgatccc tttgatcaaa
    71101 tacattcctg aaactagcgt agttgatcta aaaggggtac tccaagaagt aaaacgttcc
    71161 ttgatcaatg aaatggactt cttaaaagaa agtcaaaatg gcgaacaatt ctatcaaaag
    71221 aacaatggct ggaaagagat ccgcagcccc aagatttatg acgctttttg ttcgaaaaaa
    71281 gtgatcgtga tggaagaaat gtctggtaaa aacttgaatc atttaatgaa cgccgaaaac
    71341 aaaactgaaa cttttatcac tggaattcaa aacaagcagc tgaaacaaga agttgcaaag
    71401 cttttagttg agaactttat gaaacaggtg tttgatgatg gttttttcca tgctgatcct
    71461 catccaggga atctgctatt ccatgtacta acaaaagaag aacagacaca agctagccga
    71521 aaaactgaaa cagtccatga aaaagagttc ggttcctttg cttttcgagc ctccacttct
    71581 gcagaagacc ctgttgcgcc atataccatc aactacatcg attttggtat gatggggcat
    71641 ctttctgcag gacttaggca aaaactcaca caagccgttt tagcgctgta tacgaaagat
    71701 gcttatcgaa tcgaaaaagc ggtccttcga ctttgtcagc aagaaggctc gtttgatgaa
    71761 agtcggttcc accaagaact gacaagtttt cttgaacagt attatgattc tcctattgat
    71821 gaaatcaact tgcaagaagt attcacacat gtcgtgacga tttgtcatca aaataatctg
    71881 cagttcgatc gtgatatcac gcttttgctg aaagcatttg ggacattaga aggggtgatc
    71941 cgcgtcctcg atcctgaagt ttccctcatg gaagtcgctt cgccttttgc tcaacattat
    72001 tttctcactc atctggatgt agaagataca ttgaaacaaa gcggattaga cttattggaa
    72061 gggatgaagg ctgcgcctaa gatccctcaa cagctccacc atctattaga aatgtggact
    72121 tcgggacaag gaaaagtcaa tttggaattg aaaaagcaag acaaattatt gagcaggatc
    72181 gaaagtatga tcaatcggct tgttttcggt atgattttag ctgcattgat cgtagggtcc
    72241 tccctgcttg tccaagcagc acctgtagaa aacgcagagg tcgtttcctt attagggata
    72301 tttacgtatg ctattgccgc attcgtcatt atttttttgg caatcgatgc attgatccaa
    72361 atgtataaga agaggaaaaa gtagaaaaag gttgtgacag aaagaatcag cttcaagaaa
    72421 taagaagggg ttttacataa attgtttctc aaatttttgt gaaaattcgg cttatttttc
    72481 gaagaggcta cttctgaaac accgagaata aaaaatgtga aaaagctgtt ctgcacccag
    72541 taataagaac aatcaaaaag ggaacatgga acacatttat cctgtttccc tgttcccttt
    72601 ttgatgtatt cgagcataaa taaaatacct tcgttaccta ctatcttctg tacttggtaa
    72661 accttagtca attgcctttt ttaacgcttg acgaaaagac atatgatctt tctccgtaaa
    72721 gggttttgga ccctttgtcc ttatgccagc ttttcttaac tttccactat gataacgttg
    72781 ttctagaagc gtgccgatat tcgcttcgtc aaattctttt ccagagtgat ggaacactcg
    72841 cacacccttc ggcaatacaa gtgaagctaa accataatct tgcgtgatca aaaagtcatt
    72901 cttcttaacc ataccgacga ttttataatc cgcactatca gctccgcggt ctacgtagac
    72961 gatttggaca tgattagcgt attctttggt cgtataatgg tccacactgg tcacgataac
    73021 cacgtcaaga ccataggatt ctcctaattt tatgacatct tcttttactg gagaaccatc
    73081 tccatcaatg aatagcctca ttctttttcg ccttcttcca taaatgataa acagttacta
    73141 atccgctcag taaaagacca acattgatcc attttgccaa gataagcagt tgtacacttt
    73201 ctatcggcac tgattcatgg ttcagcgtga tcaataatag atggattggc tctcccattt
    73261 cttttgctaa aacaaacaaa agcgtcatca ataaaaactg gtggatcaca ctccctttat
    73321 tttgagtagt atacttgaca acgatccggc gatccattgg aatagctgta tcagtttgat
    73381 aatattcctt atttagccag ctgcctgtta ctacgtgcca gaaactaagc agaaagacac
    73441 ctatcgcaaa accatttgga atcaagagga ccaataaaga agaactcagt ccaagcaatt
    73501 gcatagccaa tggagaccat gttaaacgtt tcaaaatcca tggtccgact atttttgctg
    73561 caatcaagcc tgctgcataa ggcaaataca taaaaatcga aagtttttct aatccgtaca
    73621 gtatgccaac ataaaaactg ctaaataaaa aaaggaaatt ccctagcatt ccatttagaa
    73681 aagtaaacag atttagccag cttggcaact tccattcctt cttctggtgt cctaaaacaa
    73741 acacgaacaa gatgaacagc agcaagaaac cataaatagc aagatcaaaa agcctttcat
    73801 cgaataacaa tcgggcattt ctcaaaagaa acaataagcc aaagaatatc aaaaataaaa
    73861 caagctctcg cgtagctacc agatttcttt tgatgtcttt gaaatccagt tcgtaacgcg
    73921 gataatgact aaccgtatgg taggccatga cgtaaaaaag tgtataaata gtaaagcttg
    73981 ctgcaatctg agtcggtgca ggcaactcaa tcgcttgata caggagaaat agccagatag
    74041 ctgcaaataa gtactttttc ccatccatat tgataaaacc ttgcgtcttt tcgtgaaaat
    74101 tgaccgtggt attagcaggt acaagccatg ctgcactcag ccctagcaaa acacttgaaa
    74161 aataaaataa aggaaaataa aatacgccta atattccaag caatgaacca gcaccaccaa
    74221 tcagcagagc gatcatcagc aacgtgtaac tatctagacc aaatcgtaga ctgttgacta
    74281 aaaatagtcc agtcatccga aaggcataaa acagcgtaaa tggcaaaatc gtcagccaat
    74341 tatgcgagtc tgttagtccc aaaaataaaa gataaggaat aaaaataacc gtgttactta
    74401 agataaaggg cgttgtttgt gtaaaattac gcccaaatcg tttgagtttt tcgaacatga
    74461 caatggctcc ttaaacagtc ttataactaa tctgctcttc gattttagca ttaaagggga
    74521 aataaaccaa ttttacagaa tatattcttg taaaaaaaaa tacagaaaga agcataagct
    74581 tctttctgca tttttacggt acttgattac tcaagcagac aagcccttct ccacaaaagt
    74641 cttgcccgac acccctgcat ccggcaggtg ataaagatag aaatcaatta tcctgtgcct
    74701 ccaaaatcaa ttaggagctc tgtaaaccag agtccttctc gacccgtcgc ataaatttac
    74761 tttaacacag ttcctatgtt tatgcgagag cttttttcat tttataatcg accatttgaa
    74821 atccttgacc gatatctgaa ataagttctt ctgtaatctc aaatccttca tgcttataaa
    74881 cctcgattgc ttgatgattc ccctgattca ctcgcaaaaa gatctctctt tcctttgttt
    74941 gcgcagcaag ttcttcatac cagcgaaaaa ctgaagaagt caatccttga ccacgtactt
    75001 tatttagcaa atataattta cttaaataaa tttttccatt tatctcttca taagcagtgt
    75061 aaccgacagt cttttcttcg ctttttaata aaaagtagga cacaccttct gtcagttctt
    75121 tttgaatctg tttttttgac tgataagttt tcagcatgta atccacttgt ttttgaccaa
    75181 tgatcggcac aaaaacttcc ggccatactt cttgtatgac tgccatcagc tcatccagtt
    75241 cattttctgt tacttttatt ttttccatac acccacgtcc ttttttacat tataaatgac
    75301 cttgcgcttg atggaataaa aagagcatga tcatgctata cacacccacc gaccacggtt
    75361 tcaagaaaat cacaatctgc ataaattccc taaaagataa tttcgtcaaa ccagctacta
    75421 gacagatcaa gtcgtctggc gcaaagggaa gcagcaaggt aacaactagt acttttttaa
    75481 tatctttcgt ttttcttgtc agcaattcat caaatttctg atactttttt ggcgataaaa
    75541 taagctggac aaaggctacg ccatagtaac ggacaagcaa aaatccgatt gcttccccaa
    75601 tcactaggcc aatacaacta tataaaagcc caaatccatt gccaaacatc agcatgcccg
    75661 ctactgagga gatccctccc ggcaaaatag gaatgatcac ttggatcact tgcaacagaa
    75721 caaatatcat cactgcatac ttgccaaatt gctggataaa cgcttgcaaa gacgtgctcg
    75781 atcgaaaaat cccatgatga taagcataaa gaatcaacac aaagaaaaaa aacagaccaa
    75841 taatgggcat gatctgaaga catttttgta aaactgatcc ttttttagac atctatattc
    75901 cccacatctt ttttcattta ttaaaactgc ctcct
//
LOCUS       DAZAOD010000006        70954 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000006 DAZAOD010000000
VERSION     DAZAOD010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 70954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.006"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            57..287
                     /locus_tag="ACHDPO_000428"
     CDS             57..287
                     /locus_tag="ACHDPO_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFN3368091.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            384..1685
                     /gene="murA"
                     /locus_tag="ACHDPO_000429"
     CDS             384..1685
                     /gene="murA"
                     /locus_tag="ACHDPO_000429"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFN3368092.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1698..1874
                     /locus_tag="ACHDPO_000430"
     CDS             1698..1874
                     /locus_tag="ACHDPO_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFN3368093.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2009..2305
                     /gene="yidD"
                     /locus_tag="ACHDPO_000431"
     CDS             2009..2305
                     /gene="yidD"
                     /locus_tag="ACHDPO_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFN3368094.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2490..2957
                     /locus_tag="ACHDPO_000432"
     CDS             2490..2957
                     /locus_tag="ACHDPO_000432"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368095.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3042..3926
                     /locus_tag="ACHDPO_000433"
     CDS             3042..3926
                     /locus_tag="ACHDPO_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFN3368096.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4040..4276
                     /locus_tag="ACHDPO_000434"
     CDS             4040..4276
                     /locus_tag="ACHDPO_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFN3368097.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4364..4444
                     /locus_tag="ACHDPO_000435"
     tRNA            4364..4444
                     /locus_tag="ACHDPO_000435"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4398..4400,aa:Tyr,seq:gta)
     gene            4451..4522
                     /locus_tag="ACHDPO_000436"
     tRNA            4451..4522
                     /locus_tag="ACHDPO_000436"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4483..4485,aa:Gln,seq:ttg)
     gene            4647..4817
                     /locus_tag="ACHDPO_000437"
     CDS             4647..4817
                     /locus_tag="ACHDPO_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368098.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5037..5744
                     /locus_tag="ACHDPO_000438"
     CDS             5037..5744
                     /locus_tag="ACHDPO_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3368099.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5803..6447)
                     /locus_tag="ACHDPO_000439"
     CDS             complement(5803..6447)
                     /locus_tag="ACHDPO_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFN3368100.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6573..6860
                     /locus_tag="ACHDPO_000440"
     CDS             6573..6860
                     /locus_tag="ACHDPO_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368101.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6968..7288
                     /locus_tag="ACHDPO_000441"
     CDS             6968..7288
                     /locus_tag="ACHDPO_000441"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3368102.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7369..8682
                     /locus_tag="ACHDPO_000442"
     CDS             7369..8682
                     /locus_tag="ACHDPO_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFN3368103.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8679..9398
                     /locus_tag="ACHDPO_000443"
     CDS             8679..9398
                     /locus_tag="ACHDPO_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFN3368104.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9526..10077
                     /gene="raiA"
                     /locus_tag="ACHDPO_000444"
     CDS             9526..10077
                     /gene="raiA"
                     /locus_tag="ACHDPO_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFN3368105.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10299..12833
                     /gene="secA"
                     /locus_tag="ACHDPO_000445"
     CDS             10299..12833
                     /gene="secA"
                     /locus_tag="ACHDPO_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFN3368106.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            12959..14060
                     /gene="prfB"
                     /locus_tag="ACHDPO_000446"
     CDS             join(12959..13030,13032..14060)
                     /gene="prfB"
                     /locus_tag="ACHDPO_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFN3368107.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14165..14851
                     /gene="ftsE"
                     /locus_tag="ACHDPO_000447"
     CDS             14165..14851
                     /gene="ftsE"
                     /locus_tag="ACHDPO_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFN3368108.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14844..15728
                     /gene="ftsX"
                     /locus_tag="ACHDPO_000448"
     CDS             14844..15728
                     /gene="ftsX"
                     /locus_tag="ACHDPO_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFN3368109.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            15880..17328
                     /gene="cls"
                     /locus_tag="ACHDPO_000449"
     CDS             15880..17328
                     /gene="cls"
                     /locus_tag="ACHDPO_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFN3368110.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17665..18522
                     /locus_tag="ACHDPO_000450"
     CDS             17665..18522
                     /locus_tag="ACHDPO_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFN3368111.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18637..19557
                     /gene="pstC"
                     /locus_tag="ACHDPO_000451"
     CDS             18637..19557
                     /gene="pstC"
                     /locus_tag="ACHDPO_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFN3368112.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTITTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19557..20441
                     /gene="pstA"
                     /locus_tag="ACHDPO_000452"
     CDS             19557..20441
                     /gene="pstA"
                     /locus_tag="ACHDPO_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFN3368113.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20456..21262
                     /gene="pstB"
                     /locus_tag="ACHDPO_000453"
     CDS             20456..21262
                     /gene="pstB"
                     /locus_tag="ACHDPO_000453"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFN3368114.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21278..22036
                     /gene="pstB"
                     /locus_tag="ACHDPO_000454"
     CDS             21278..22036
                     /gene="pstB"
                     /locus_tag="ACHDPO_000454"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFN3368115.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22049..22726
                     /gene="phoU"
                     /locus_tag="ACHDPO_000455"
     CDS             22049..22726
                     /gene="phoU"
                     /locus_tag="ACHDPO_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFN3368116.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23303..23995
                     /locus_tag="ACHDPO_000456"
     CDS             23303..23995
                     /locus_tag="ACHDPO_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFN3368117.1"
                     /translation="MLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISIL
                     FVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVI
                     GSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPIS
                     VLFFLTVRRLKR"
     gene            23992..24759
                     /locus_tag="ACHDPO_000457"
     CDS             23992..24759
                     /locus_tag="ACHDPO_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFN3368118.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24859..26427
                     /gene="liaX"
                     /locus_tag="ACHDPO_000458"
     CDS             24859..26427
                     /gene="liaX"
                     /locus_tag="ACHDPO_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFN3368119.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26724..27044
                     /locus_tag="ACHDPO_000459"
     CDS             26724..27044
                     /locus_tag="ACHDPO_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFN3368120.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPFARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27044..27394
                     /locus_tag="ACHDPO_000460"
     CDS             27044..27394
                     /locus_tag="ACHDPO_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFN3368121.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27561..28499
                     /gene="hprK"
                     /locus_tag="ACHDPO_000461"
     CDS             27561..28499
                     /gene="hprK"
                     /locus_tag="ACHDPO_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFN3368122.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANKNGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28514..29344
                     /gene="lgt"
                     /locus_tag="ACHDPO_000462"
     CDS             28514..29344
                     /gene="lgt"
                     /locus_tag="ACHDPO_000462"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFN3368123.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29388..30413
                     /locus_tag="ACHDPO_000463"
     CDS             29388..30413
                     /locus_tag="ACHDPO_000463"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFN3368124.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30428..31366
                     /gene="galU"
                     /locus_tag="ACHDPO_000464"
     CDS             30428..31366
                     /gene="galU"
                     /locus_tag="ACHDPO_000464"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFN3368125.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31491..31931
                     /locus_tag="ACHDPO_000465"
     CDS             31491..31931
                     /locus_tag="ACHDPO_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFN3368126.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            31934..32536
                     /locus_tag="ACHDPO_000466"
     CDS             31934..32536
                     /locus_tag="ACHDPO_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFN3368127.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32595..33701)
                     /locus_tag="ACHDPO_000467"
     CDS             complement(32595..33701)
                     /locus_tag="ACHDPO_000467"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFN3368128.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            33911..34912
                     /gene="ccpA"
                     /locus_tag="ACHDPO_000468"
     CDS             33911..34912
                     /gene="ccpA"
                     /locus_tag="ACHDPO_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFN3368129.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35249..37594)
                     /locus_tag="ACHDPO_000469"
     CDS             complement(35249..37594)
                     /locus_tag="ACHDPO_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFN3368130.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            37873..38775
                     /locus_tag="ACHDPO_000470"
     CDS             37873..38775
                     /locus_tag="ACHDPO_000470"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFN3368131.1"
                     /translation="MLLGSHVSMSGKKMLLGAAAEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            38988..40763
                     /locus_tag="ACHDPO_000471"
     CDS             38988..40763
                     /locus_tag="ACHDPO_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFN3368132.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(40829..42415)
                     /locus_tag="ACHDPO_000472"
     CDS             complement(40829..42415)
                     /locus_tag="ACHDPO_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFN3368133.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETVEEIE"
     gene            42666..42890
                     /locus_tag="ACHDPO_000473"
     CDS             42666..42890
                     /locus_tag="ACHDPO_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFN3368134.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            43031..44782
                     /locus_tag="ACHDPO_000474"
     CDS             43031..44782
                     /locus_tag="ACHDPO_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFN3368135.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTK
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIVMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPVKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            44782..46566
                     /locus_tag="ACHDPO_000475"
     CDS             44782..46566
                     /locus_tag="ACHDPO_000475"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368136.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRTTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVLVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            46892..47743
                     /gene="licT"
                     /locus_tag="ACHDPO_000476"
     CDS             46892..47743
                     /gene="licT"
                     /locus_tag="ACHDPO_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFN3368137.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            47839..49719
                     /locus_tag="ACHDPO_000477"
     CDS             47839..49719
                     /locus_tag="ACHDPO_000477"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFN3368138.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEAEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVSFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYIMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVRQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(49759..50661)
                     /locus_tag="ACHDPO_000478"
     CDS             complement(49759..50661)
                     /locus_tag="ACHDPO_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFN3368139.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            50892..52295
                     /locus_tag="ACHDPO_000479"
     CDS             50892..52295
                     /locus_tag="ACHDPO_000479"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFN3368140.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            52295..53728
                     /locus_tag="ACHDPO_000480"
     CDS             52295..53728
                     /locus_tag="ACHDPO_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFN3368141.1"
                     /translation="MGFRKDFLWGGATAANQCEGAYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSNN"
     gene            53873..54799
                     /gene="trxB"
                     /locus_tag="ACHDPO_000481"
     CDS             53873..54799
                     /gene="trxB"
                     /locus_tag="ACHDPO_000481"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFN3368142.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            55013..56740
                     /locus_tag="ACHDPO_000482"
     CDS             55013..56740
                     /locus_tag="ACHDPO_000482"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFN3368143.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            56755..57105
                     /locus_tag="ACHDPO_000483"
     CDS             56755..57105
                     /locus_tag="ACHDPO_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFN3368144.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(57197..58057)
                     /locus_tag="ACHDPO_000484"
     CDS             complement(57197..58057)
                     /locus_tag="ACHDPO_000484"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFN3368145.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            58149..58577
                     /locus_tag="ACHDPO_000485"
     CDS             58149..58577
                     /locus_tag="ACHDPO_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFN3368146.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            58739..58915
                     /gene="rpsU"
                     /locus_tag="ACHDPO_000486"
     CDS             58739..58915
                     /gene="rpsU"
                     /locus_tag="ACHDPO_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFN3368147.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            58942..59388
                     /locus_tag="ACHDPO_000487"
     CDS             58942..59388
                     /locus_tag="ACHDPO_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFN3368148.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(59542..60921)
                     /gene="brnQ"
                     /locus_tag="ACHDPO_000488"
     CDS             complement(59542..60921)
                     /gene="brnQ"
                     /locus_tag="ACHDPO_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFN3368149.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            61627..62598
                     /locus_tag="ACHDPO_000489"
     CDS             61627..62598
                     /locus_tag="ACHDPO_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFN3368150.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            62622..64814
                     /locus_tag="ACHDPO_000490"
     CDS             62622..64814
                     /locus_tag="ACHDPO_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFN3368151.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            64831..65307
                     /gene="ybeY"
                     /locus_tag="ACHDPO_000491"
     CDS             64831..65307
                     /gene="ybeY"
                     /locus_tag="ACHDPO_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFN3368152.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            65291..65686
                     /locus_tag="ACHDPO_000492"
     CDS             65291..65686
                     /locus_tag="ACHDPO_000492"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFN3368153.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            65701..66600
                     /gene="era"
                     /locus_tag="ACHDPO_000493"
     CDS             65701..66600
                     /gene="era"
                     /locus_tag="ACHDPO_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFN3368154.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            66743..67555
                     /gene="recO"
                     /locus_tag="ACHDPO_000494"
     CDS             66743..67555
                     /gene="recO"
                     /locus_tag="ACHDPO_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFN3368155.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            67939..68856
                     /gene="glyQ"
                     /locus_tag="ACHDPO_000495"
     CDS             67939..68856
                     /gene="glyQ"
                     /locus_tag="ACHDPO_000495"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFN3368156.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            68858..70933
                     /gene="glyS"
                     /locus_tag="ACHDPO_000496"
     CDS             68858..70933
                     /gene="glyS"
                     /locus_tag="ACHDPO_000496"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFN3368157.1"
                     /translation="MAKDLLLEIGLEEIPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKQYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        23208 a        12438 c        15212 g        20096 t
ORIGIN      
        1 tatggtatta tcattttatt agttattata aaacaatcgt tagaaaggac gtcattatgc
       61 aagtatacgg aattgatgcg gtgcttcgaa tcgtgagtca tttggcgttt atctacttag
      121 ccttctggtc tttacgttcg ttacgcattg aaactttttt cagaccaatg cataatacgc
      181 aaattagaat ggcaatcgta cttttttcaa tttttttagg gtacactgca agtaattttt
      241 tcttagaagt tatcgcttta tgccgaaatc ttttcgttag cctgtaaatt ttaaaaaaag
      301 gtactatttt aaaagcaagg atgttataat agaaaagatt ttgagtaagt gtatgctcat
      361 tggaattttt tggagggaac aacatggaag agatcatcgt aagaggtggc aatcaattaa
      421 atggaacagt aagaattgaa ggagctaaaa atgctgtttt gcctatttta gctgctagtt
      481 tgttagcaga agaaggtatt acgacattag acaacgttcc gattctttct gatgtcttca
      541 ctatgaatca agtgattcgt cacttaaacg tagatgtaga ttttgatgaa caaaagaatc
      601 aagtaacaat cgacgcttca agacaattag aaatcgaagc gccttatgag tatgttagtc
      661 aaatgcgtgc ttcaatcgtt gtgatgggtc cgctacttgc cagaaatgga catgcaaaag
      721 tagctatgcc tggtggatgt gcgattggta aacgaccaat cgatttgcat ttaaaaggat
      781 ttcaagcttt aggagcaaaa attattcaaa aaaacggcta tatcgaagca attgcggatg
      841 aattgatcgg taacacgatt tatttagatt tccctagtgt aggtgctact caaaatatca
      901 tgatggctgc cgtaaaagca aaaggaacaa ccatcattga aaacgtagct cgcgaaccag
      961 aaatcgttga tttagcaaac attttgaata aaatgggcgc tcaagtctat ggagctggta
     1021 ctgaaacaat gcgtattgaa ggcgtggatc atttacatgc agtcaaccac tcaatcgtac
     1081 aagatcgtat cgaagcaggt acctttatgg ttgctgctgc aatgacacaa ggcaatgtgc
     1141 tgattgcaga tgctatctct gaacataacc gcccattgat ttctaaattg atcgaaatgg
     1201 gtgcagaaat cattgaagaa gaaggcggag tccgtgtcat cggaccaaaa catatcttac
     1261 ctacagatgt aaaaacgatg cctcatcctg gtttccctac agatatgcaa gctcaaatga
     1321 cagctatcca attagttgca gaaggtacaa gtgtagtgac tgaaacagtg tttgaaaatc
     1381 gtttccaaca tttagaagag atgcgccgta tgaacgctca tgtcaaaatc gacggaaatg
     1441 tagcaatcat ggatggaaac catgaattgc aaggtgcaga agtatatgca acagacttgc
     1501 gggcagcagc agcattagtt ttagctggct tgaaagcaaa tggaatcaca cgtgtgcgta
     1561 acttgaatta tctagaccgt ggatattata atttccatat caaactacag caattaggtg
     1621 cagacgttga acgtgtagac atggatcaaa cttctgctga aaaaacagca caaacgattg
     1681 cttaaggaag tggctgaatg agtaaccaac gatatatctt attaactttg ataaagattt
     1741 taatggtgat cttattgctt atccttcttt ttgtggccgg aacgatgatc ggatatggtg
     1801 tcatcggtgg cggcaatcca tttaaagtat ttcagccaag tttgtggatt catattcgag
     1861 acttttttca ttgataaata agaatcacag tggttctagt cgatatgaag tgagccatga
     1921 agcagaacat gataaaagaa aacagaaggg aacgttgacg ttagtcgcga tccctttttt
     1981 tagtaaaaga aaagaaggaa tctaattgat gaagaagata ttgatttatt tagttagagg
     2041 atatcagcgc tttatttcgc ctgcatttcc acctagctgc cgttattacc caacctgttc
     2101 caattatatg ataaaagcaa ttcaaaccca tggcgcgcta aaagggacgg taatggggac
     2161 tgcacggatc ttacgctgtc atccttttgt caaaggcggt atcgattatg taccattgac
     2221 attccgatta acgcgaaata agaaagataa aaaagaacca gattataaaa aggttgtgaa
     2281 aaatacgggt agcactgagc gataaagaaa caatttggaa aatagcttct tatattttgc
     2341 aaaattgtga gttattgccg aagtgttgga ttttgaacac cgtcaaaaaa aaggttgtga
     2401 aaaatacggc tagcactgag cgataaagaa aaagaggaaa tttattgtca aagtaacaac
     2461 tccgcaacta cttatatggg ggacaaaaaa tgatcgaaga actaaacaag aaagatttac
     2521 catggtcctt gttattagat gcagatcctg ataaagaaaa agttcaagta tatgtttcca
     2581 gagggagtgg ctggatatgg aaagaaaaag aaaaaacaat aggtgtactg atctatgtgg
     2641 caagggaaaa agaatacgaa atcgtcaatg tagcagtaac cccaacgtat caaggaaagg
     2701 ggattggcgg aaaattactt gagacagctt ttcagaagct ttcacaactc gcttccagtc
     2761 aaactcagat catcatacga accggcagta ctagcagtgc ggcgttacat ctctatcaaa
     2821 aaatgggcta tgtggagatt ggtcgagtca aagactattt tatccatcat tactctgagc
     2881 ccatttttga aaatggagat caattaaggg atcaagtgat tttagcaatt cacttaccta
     2941 aaaatagctt taactaataa aatttcaatt caagaaaatg ctttcaaatg ctaaatagat
     3001 acattacaat agctttagca aacaaaaagg agaatatttt tatgggaata ttagtttttg
     3061 attttggtgg atcggctgtc aaatatggtt gttgggatgg caaagagatt aaaggtaagg
     3121 gacaatttgc aacgcctgaa tcttgggaag aaatgaaagc gcaattattt caagtttata
     3181 aaaaaatact cgtttctttt gaagtcgaag gaattggaat cagctctcct ggagtagtga
     3241 ataatgagaa acaggtgatt gagggaatca gtgcgattcc ttatattcat ggatttaata
     3301 ttttccgaga tttggaaact ctgtttcaac ttccagtaac gattgaaaat gacgccaact
     3361 gtgccggaat ggctgaattt tatgaaggtg ctgcccgcga ttatcaagat gttgcttttg
     3421 ttgtggcagg aactgggatt ggcggggcgt tgttcacgaa aggacaaatc aataaagggg
     3481 cacatcttta cggtggagaa tttgggttga tgttcttaaa tggcgataag acattcagta
     3541 aacttggtac agcggtacag atggcttggc gttattgtga acgcaaaggt ctcgataaaa
     3601 atgcttatac cggaaaagat gtctttgaat tagcagaaac tggagatgca atagcaaaag
     3661 aagaagttga gagtttttat acgtatctta caaagggatt attcagtatt caattttcgt
     3721 ttgatccaga agtgatcgta ttaggcggcg gggtttctgc aaaagaaggg ctcattgatg
     3781 agatcaaaag ccgaatgaag aagctgacag aacaattcga tctgcatgat ttcgaaccgc
     3841 agattttatt atgtgaatac agaaacgatg ctaatcttgt aggtgcagca gcaaactatc
     3901 tcgctgtacg tcaaggggag aattaagagc tttagagaag gtgcagcttg cataaaagaa
     3961 gtgaatgaaa tgaataggag atttttacct aaggaatgtt ttatttgctg cagtatgata
     4021 aaatatctga gaggtgaaaa tgatgtcaaa aaaaaataaa gatattgaag tgcgtataga
     4081 agaagtgaaa aaagatatca aaggtaagaa ttatgaagtc actcagttat ttatagggaa
     4141 aaaaatgatt ggtgagatct tagcctatgg accaaaagaa tatgaaattt tctttggtga
     4201 agaagatttt ggaaaagaaa aaagtcttga aaatgcgata gaaacagtga ttcgacactg
     4261 gaatctgcac gaataaaaaa atatcaaaaa aactttcaat aaagggttgc aaaaatctgg
     4321 aaaattaggt attataacta agtcaggttg atacaaacct ttcggaggag tagcgaagtg
     4381 gctaaacgcg acggactgta aatccgttcc ttagggttca gtggttcgaa tccactctcc
     4441 tccatttcat tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt
     4501 ggttcgaatc cagctacccc agtataccac aatcgtaagc tctcgttagt tcgagagctc
     4561 ttttttttgc tttgctacct tgttccttga agattctgct gatttaagat agagttaagt
     4621 taactacaag aattggaggg atccacatga aatggaaaga aaaagtagac gaagcagctg
     4681 aaaagttata tgatttggtc aaatcagaaa aatacaatat tgaagtgaat attccgaaaa
     4741 aaggcggaaa agcggtccgg gtaaaatcaa aacgcccaac gaatcataca aaaaaatgga
     4801 tggctaaaaa ccgctaataa taacaaaaga tccataagtc ggcattttca tcgattttag
     4861 ggtcttttgt tattttctag gttggacata tctaaaaaat tgtttctgac aataggagta
     4921 ggaagaacga tgtgtgtcta aatcctctgt tgatggatag aaacctttat ctttttcagt
     4981 tgtgaatcag gtatatacca gttataatag aagaaacgaa aggacgggtg tacgttatgt
     5041 cgaatcaatt acctgtatat atacagattc atgaccaatt aaaaaatgaa atcgaacaag
     5101 gtatatggaa agtcggagac cgtcttcctt cagaaagaga attagcagtg aaattcaatg
     5161 tcagccgtat gacgttgaga caagcaattc aaaacttggc agatgaagga atcttagaaa
     5221 gaaagatcgg ttcgggtaca tatgttgcac gagaaaaagt acaagaaaaa atgtctggtg
     5281 caacaagttt tacagaaatt atggaatcac aaaatcgagt accgtctagt cggacaatct
     5341 cttatttctt gacttcgcca agctcaagtg aaatggaaaa actaaacttg agtaaagatg
     5401 acacgatctt gcgaatggaa cgtattcgtt tcgcagatga tgtccctatt tgttttgaag
     5461 ttgccagtgt gccacaaaag ctgatcgatg gctacagcaa agcagagatt actgaatcgt
     5521 tgtatcgcac gctagaagaa aaaggcggga aaaagatcgg tccagcgaat caaacgatta
     5581 ctgctgtgtt ggcttctgag aaaattgctg actatttaga ggtaaaacga ggagatgcag
     5641 ttcttcgttt gcgccagatt tcttattttg aagacggtac gccgtttgag tatgtgcgta
     5701 cgcaatacgt aggaaatcgt tttgagtttt atttggaaaa ataaaaaaca ggtgatccct
     5761 gattccgtat tagaaataaa agagaatcag aatcacctgt ttttatatat gatcagttac
     5821 cagttgctcg tgataagaaa caggaccctc ttcaaattgg acttgtccgt tcagcagctc
     5881 aatgatggat tctttaaagt ggtcagcact tttttcatct acagcacaga tgacgctaac
     5941 ttgatcagta tattggattt cttttataaa aaaatgttgg agttcaagat aattctgtaa
     6001 ttttcctagt tgcggatacg tgatcatcac agagatctcc tgttgcaagg taccttctac
     6061 gattccaatg tcagacaatg cttgagagac cgcatgagtg tatgctcgta ttaatccgcc
     6121 tgtgccgagt ttcgttcctc caaaatatcg agtgactact gcagctacat tgatcagttg
     6181 attttttttg aggacttcca acatcggtat gcccgccgtt ccacttggtt ctccatcatc
     6241 gctgcttcgc tggatttcat ttttttctcc aatgatgaag gcgctgcagt tatggttcgc
     6301 tttccaatgt tcttttttta tttcttgaat gaaacttttt gcttcgtcct ctgattctat
     6361 tcgtctaaga gaacagataa agcgtgattt tttgatctcg atctcacttt gtccattttc
     6421 ttttattgta cgatagcgct cgatcatctt gtcacctctt ttttcatttt ctttattcag
     6481 tataaataaa gttctaggtt gtttcaacac tgtaacggtt gcgcaattgc tgtagtatgc
     6541 gataataaag acaaaggcag gtggatctgg ggatgcagga acgaatgaaa aagtacgatg
     6601 caattacgca ttatttgaag aacaatggcg gctctcaagt aacgttgacc tttacccaat
     6661 ttgacgaact gctgtttccc agtaacggac ttcccaaaac agcaagggaa agtacagatt
     6721 ggtgggcaaa tgattataaa caccctgaaa aaggtgccta tggctggata aatgcaggct
     6781 atgaagtagt tgtcatcaat ttggacaaag aatatgtcgt gttcaataaa ttagtgaaat
     6841 ctagttggct atttgattaa ataaaccgcg tttagaaaac gttgacaaat ttctttcttt
     6901 ttatataata gagtaacaga cgcgaagaaa acgtttgcgt agtttgtttt aaaaaggaga
     6961 gaaaagtatg gctaaaaaaa caatcatgct tgtatgttcg gctggtatga gcacaagttt
     7021 actagtaaca aaaatgcaaa aagctgctga agcaaaagga atcgactctg atattttcgc
     7081 tgtgtccgct tctgacgcag ataacaatct tgcaaataaa gacgtggatg tgttgttatt
     7141 aggcccacaa gttcgcttta tgaaagctga ttttgagaaa cgtctggaac caaaaggcat
     7201 tcctttagat gtcatcaata tggctgatta tggtatgatg aatggcgaaa aagtgttaga
     7261 tcaagcaatc acgctcatag gtgaataaat agaacagtat aactatcgaa caagcgatcc
     7321 aaaaaataga tcgcttgttt tttcgtatat ttttttaggg cgaataatat gaatcatttt
     7381 tggggtagaa ggcttctgac gagagatatt aaagcaatag actgtgagga ggtaaattta
     7441 ccaaattatg agaagatcgc agcagtggaa cgtttgagca actggattct ttgtcatcgc
     7501 tgtggaatga gaacgtccgt cattgatgga cagcttgcag attacggtta tttttgtaca
     7561 cattgtctat atttagggcg atgcgacact caacaagatt tatatttgtt tgatcagcct
     7621 gaagcaaaac ctcgagaagt cgtctttttt tggacaggac agcttactga aaaacaaacg
     7681 gaaatctcaa agagaatact ttgccattca gaaaaaagac atcatcttat ttgggctgta
     7741 acaggtgcag ggaaaacaga gatgctttat cctattttag tggaaacttt aaaagctgga
     7801 ggaagagtag cgatttgtac accgcgagtc gatgtttgta atgaattgtt tttacgctat
     7861 cgttatgttt ttccagaaga aaaaatcacg ttgctccatg ggaatacagc aacggcttat
     7921 acctttactt cttttgttat ctgtacgatt catcagctat accgttttta tcggtccttt
     7981 gatttaatag tgatcgatga gatcgatgcg tttccttata acggggatgc aggattagct
     8041 catgctgtgc aaacagcgat taaaccagac ggacgattca tctacttaag tgccacacct
     8101 gataaaaagt tactaaagga gatcaagcag acgtttgaca tccacaaact tgctttacgc
     8161 tttcatcggc gtttgcttcc tgaacccgtc ttggttttca tgaataattg gcgacaaaaa
     8221 tgcaagaaca agaagaagat aaaatctttg gtgcggatca ttcatcaatt aattaaagaa
     8281 aaccatatcc ttttattttg tccaagtatc acgatgatgc atcgtttgaa agccacactt
     8341 caagaggctc ttccgagata tgagatcaca gatgtttctt caagagacaa tcagcgggcg
     8401 gaaaaagtcc agaaaatgcg agaagcaaaa tatgacatac tgttaaccac gatgatcctt
     8461 gaacgtggag tcacatttga aagaatatcc gttatcgttt taggagcgga tcatccggtt
     8521 tttactaaat cttctttggt acaaatcgca ggaagagccg atcgtaaagg gccttatacg
     8581 aacagtcaag tatatttttt ctatgaagaa aaaactgcag ctattcgaaa agcttgtcag
     8641 gaaatcaaag aaatgaatga agaagggaag aagatactgt gaggtgcagt tgctgcagta
     8701 aagatatcgt ccaaaattta acattcagcg agattattgg tgtttcgaaa tacagattac
     8761 ctcagacttg ttcagtttgt cgcgcacaat ttcatttatt ggaaacaaga ggctgttctg
     8821 gctgtcaaaa accaatccat ttcaatctag agagtacgaa aaagaaagta aattctatcc
     8881 ccgtttactg cagtgactgt caagaatgga agaagaaata tccgacctat gattttcagc
     8941 accgtgcctt ttttgtgtac gatgaaaata tgaaggcctg gctcaatcaa tacaagttta
     9001 tgggagatat ccgactagca ggcacctttg catataaatg gacgcagata aaaaaagaat
     9061 acccgacata catctattgt ccaatacctt tatctgaaaa aaggcgaaca gaaagaggat
     9121 tcaatcaagt aagcgagatg ttgaaagcag caagaattcc ttttcagatg ctactcaaaa
     9181 gagagaagca tctgctggct caagcaaaaa acacgcgaaa ggaaagattg gagatgcctc
     9241 aaccttttga acttgcagtc accttttcta agatacaaaa taaaaaaata ttgattattg
     9301 atgatgtcta tacaacagga cagactcttt tccacgcagc agattgtttg cagatcgcac
     9361 agccgaaaat catccgaact atttctttgg cgagatgaat tagatgtgga aatttgatag
     9421 cgatttaatt tgcaaataac ctagagttcg atataataga attaagaaga gggaaagagt
     9481 ggtccttctc cttcttgatt gtggtagacg aaaggggtaa tttttatgtt tagatataat
     9541 gtacgcggcg aaaatatcga agtaactgaa gcgattcgcg actacgttga gaaaaaagta
     9601 ggcaaactag aacgctattt cagtgacgca cccgatgcaa cggcgcatgt gaacttaaaa
     9661 gtttatacag aaaaaacagc aaaagtggaa gtaacgatcc cattacctta tcttgtatta
     9721 cgtgccgaag aaacttctcc agatttatac gcaagtatcg atttggttgt tgacaaattg
     9781 gaacgccaaa tccgcaaatt caaaacaaaa attaatcgta aatcccgtga aacgggcatg
     9841 aatactgcaa atgctgctgc tttattcaat gaagaggacg aaaacgaaaa tgattctgaa
     9901 ttagatatcg tacgtacgaa acgcctttca ttgaaaccaa tggatagtga agaagcagtc
     9961 ttgcaaatga acatgctggg acataacttc tttatttttg aagatgcaga aacaaatggt
    10021 acaagtatcg tttaccgccg taaagatgga aaatacggac tgattgaaac agactgatca
    10081 gccttactta aataacaacg aaaacttgca gcagctactg acagctgccg caagtttttt
    10141 tgagtttcct cctcttttag atgaaatatg aataaattat gaagttctta ctttaatacg
    10201 cttaagatat ttcaattatc tataactaat gataaaatga aaagtaaagt ctacatagtc
    10261 tggataatac acagaaggaa aaggagatta cacaacgcat ggccaatttg attcgttcac
    10321 ttatcgaaaa cgataagaaa gaactaaaac gtttagatag cattgcaaaa aaagttgaag
    10381 catacgctga ccaaatggca gcattaactg atgaacaatt acaggcaaaa actgctgaat
    10441 tcaagggcag ataccaaaaa ggagaaacat tagatcaatt acttccggaa gcttttgcag
    10501 tcgtccgaga agcagcaaaa cgtgtattag gtttatatcc ataccacgta caattgatgg
    10561 gtggaatcgt gcttcacgat ggaaatatcc ctgaaatgcg tactggtgaa ggtaaaacct
    10621 tgaccgcaac gatgccagta tatctaaatg ctctgactgg cgaaggggta cacgtagtta
    10681 ccgtcaatga atatttagca acccgtgact cgacggaaat gggcgaactt tataatttct
    10741 taggattaac agtggggttg aatatcaact caaaatcttc ggatgaaaaa cgcgaggctt
    10801 ataattgtga tatcacttat agtacgaata atgaattagg atttgactac ttgagagaca
    10861 atatggtcgt ttaccgccat caaatggtac aacgtccgct gaattatgcc attgtcgatg
    10921 aagttgactc aatcttgatt gatgaagcga gaacgccgct gatcatttca gggcaagcag
    10981 aaaaatccac agctttatat acaagagcag acaacttcgt gaaacgtttg aaagaagaag
    11041 aagattataa aatcgatgta caatcaaaaa caatcagttt aaccgaagca gggatcgaaa
    11101 aagcagaaga aacattcggt ttggataact tatacgacat tgaaaatact gcattgaccc
    11161 atcacttgga tcaagcattg agagccaact atatcatgct tttagatatc gattatgttg
    11221 tccaagacgg aaaagtactg attgttgacc agttcactgg tcggatcatg gatggacgcc
    11281 gttattcaga tggacttcac caagcaatcg aagctaaaga aggcgtagag atcgaagacg
    11341 aaacgaaaac catggcgacg atcactttcc agaactattt ccgtatgtac aagaaacttg
    11401 cgggaatgac tggtacagct aaaacagaag aagaagaatt cagagaaatt tataacatcc
    11461 aagtatacca gattccgaca aatcgtccgg ttatccgtga tgatcgtcca gatttgcttt
    11521 acccaacatt acaaagcaag ttccacgctg tcgtgcaaga tatcaaagat cgctaccgca
    11581 aaggtcaacc tgtgttagtc ggaactgttg cggttgaaac atctgagtta ttatcagata
    11641 tgctgaatca agaacgtatt cctcatgaag tgctgaatgc gaaaaatcac tttaaagaag
    11701 cagagatcat catgaatgct ggtcaaaaag gtgctgtgac gattgctacc aacatggctg
    11761 gtcggggaac agatatcaag ttaggacttg gggtaagaga acttggtggt ctagcagtta
    11821 tcgggacaga acgacatgaa tctcgtcgta tcgataacca gcttcgagga cgtgcaggac
    11881 gtcaaggaga ccctggtatg tcacagttct acttgtcatt ggaagatgat ttgatgaaac
    11941 gattcggttc agaacgaatc aaatctttct tagatcggat gaagatcggt gaggaagatg
    12001 ctgttatcca aagcaagatg ctgacgaaac aagtagaatc tgcacaaaaa cgtgtagaag
    12061 gaaataacta tgacacacgt aaaaacgtct tacaatacga tgatgtgatg cgtgaacaac
    12121 gtgaagtaat ctataaacag cgacaagaag taatcatgga agaaaaaagc ttatccaagc
    12181 cactaatgaa catggtcaaa cggacaatca gtcgtgtagt agatgcgcat acacaattag
    12241 agaaagaaaa ttggaatttg gaaagtatca tcgattttgc cggcagtact cttgtccatg
    12301 aagatagtat tactcttgca gatatcgaag gaaaaacagc tcaggagatc aaagagtatc
    12361 taaacgaacg agcacaagaa gtatttaata ccaaagcggc tcaactaaat ggtccagagc
    12421 aactgttgga atttgaaaaa gtcgtgatct tgcgtgttgt ggactctaaa tggacagacc
    12481 atattgatgc aatggatcaa ttacgtcagt caatcggctt acgtgcttat ggacagaaca
    12541 atccattagt cgaatatcaa acagaaggct ataagatgtt tgaagatatg gtaggcgcca
    12601 tcgagtatga agtcactcga atctttatga aagctgagat ccgtcaaaac gtacagcgtg
    12661 aacaggtttc tcaaggaaca gcttctcact cagaagacgg agatgccaaa gaaaatagta
    12721 atactagcgc gaaaaaacag ccaatccatg tgaacaaggt cggaagaaat gatccttgtc
    12781 cttgtggaag cgggaaaaaa tataagaact gtcatggaaa aaatgcaaac taatttctga
    12841 cagcaggatt ggtgagacaa attctttttt taagaattcg tctcaccttc tttctgttat
    12901 ttgctgattc tgttagacta gatataatga aaaaagtata gtgaaagaag gaaaaaacat
    12961 ggaaatatcc gaaattcgaa atctcctgac agaaatgcag gaaaaggtca caagcttcag
    13021 gaggtctctt tgacttagac cagctggaag aagacattgc ggaagcagaa gcaaaaatgg
    13081 ctgaacctgg tttttgggat gatagcgaag ctgctcaaaa agtgatcagt gaaaacaatg
    13141 caaataaaga aacttatgat caattccatt ctcttgctga agaactggaa gaaatcgaat
    13201 tgatggtgga gatgttgcag gaagaacctg atgcagccat gcaagaagaa gcagaaacac
    13261 gtatcaatgc gctagatgaa aaaatgaaga catatgaatt atctatgttg ttagatggtc
    13321 cttatgatcg aaacaacgcc atcgttgaat tgcatccagg ggctggcgga acggagtccc
    13381 aagattgggg cagtatgctt ttacgtatgt atacacgctg ggcagagcag catgggtatc
    13441 aagtagagac actagattat caagcaggtg atgaagcagg aatcaagagt gtgaccctac
    13501 tgatcaaagg acacaacgca tttggttatc tgaaatcaga aaaaggtgtt catcgccttg
    13561 tacgtatctc gccttttgac tcagcgaaac gacgtcatac ttctttttgt tcggtagatg
    13621 tgatgccaga gcttgatgaa acgatcgata tagaaatcaa tccagatgat ttgaaaatcg
    13681 atacgtaccg agcaagtggt gcaggtggtc agcacatcaa taaaacagaa tctgctgtac
    13741 ggatcactca cttgcctaca ggaacagtag tagctagtca ggcacaacgt tcacaattga
    13801 aaaaccgtga gcaagcgatg gggatgttaa aagctaagct ttatcaatta gaagtggaaa
    13861 agaaagaaca agaagcagct gcacttcgag gagaacaaaa agaaatcggc tggggttcac
    13921 agatccgttc ttatgttttc catccatatt ctatggtaaa agaccatcgg acaaacgtag
    13981 agacaggaaa tgtccaagca gttatggacg gtgaccttga tttatttatt gacggctatt
    14041 taaaaatgca tctacaataa gaacccattg ttaaattgaa ataaaattgt aagattttgc
    14101 aagcatgttg aaacattgcc atgctataat agctaaagac tgaaaaagat atggagagaa
    14161 cgccatgatt gaaatgaagg atgtaatgaa gaagtactca aatggtacga ccgctatccg
    14221 caatctctca attgtcatcg aacaaggaga gtttgtctat gtggttggtc cgtctggagc
    14281 cggtaaatct acattcatca aattgatgta tcgagaagaa aaagcttcaa aaggaacttt
    14341 gaacgtcgca ggtcatgatc taatagcaat caaaaaccgc gaagttcctt atctacgcag
    14401 agaaatcggc gtggtgttcc aagactataa attattacca agaaaaacag tatatgaaaa
    14461 tgttgcgtac gctatgcaag ttatcggcag aaaacctcgg gatatcaaaa aacgagtaat
    14521 ggaagtgctg gaccttgttg gtttgaaaca caaagttcga gtctttccta gcgaattatc
    14581 cggtggggaa cagcaacgtg tctctattgc tcgggcaata gtgaatacgc ctaaagtact
    14641 tatcgcggat gaaccgacag gaaatctgga tccagaaaac tcatgggaaa tcatgaaatt
    14701 attagatcgg atcaatgccc aaggaactac tgtcgtgatg gctacacata acagtacgat
    14761 cgtaaatacg attcggcacc gagtaattgc tatcgaaaac ggccgcatta ttcgagatca
    14821 agcggaaggg gaatatggat acgatgatta gaaccttttt ccgccattta ttagaaagta
    14881 tcaagagttt gaaacgtaac ggctggatga cagttgcttc agtcagtgcg gtaacgatca
    14941 cattgacttt agtcggtgta ttcatggcag ttatcatgaa cgcaactaaa ttagctcaag
    15001 atatagaagg aaacgttgat gtctctgtat tcgtagatat cggtacaaaa gacgaagaga
    15061 tgaaaaagct agaaaaagaa ttgaatgact tagatcatgt taaaaaagtt gaattttcaa
    15121 gcaaagaaca ggaattgaaa aaaatccaaa acgaaatggg tgattcctgg aaattgtttg
    15181 aaggtgacaa taacccgtta tatgatgtgt atgtagtaag tgctactgat ccttcttata
    15241 caaaacaagt agcagaagaa gcagcagatt tgaagaatgt ttctcgttct gattacggtg
    15301 gagcttcctc agatcggatt ttccaaatcg ctggtgcagt tcggacatgg ggattagttg
    15361 cagcggcatt gctgctgttc gtagcgatgt ttctcatttc gaacacgatt cggatcacga
    15421 ttttgtctag acagcgtgaa attcaaatca tgcgtttagt cggtgcaaaa aatggatata
    15481 ttcgctggcc gtttttcctt gaaggtggct ggatcggtct gatcggtgcg attcttccga
    15541 ttttgatcat cacatttggt tatgcatggt ttttccaatt gatcaatcca tcattattac
    15601 gttcccatta ttcattgatt catccacaaa atatcgtttg gaaaatcaat cttttaatgg
    15661 tcggcattgg tgtgatcatt ggttcacttg gctcgatcat ttctatgaga cgtttcttga
    15721 aattctaata ccacaatata aataaaatga gaaagttgga cagtttcgtt ccagctttct
    15781 ttttttattg gctaggagaa tagaaggaag cggctttttt ccctttactt taaaaaacaa
    15841 cttgggtatt cttaagttgg tagaagaaga ggtgaagccg tgaaaattat cgttgacaat
    15901 ttttttacga tccttttgat tatgaatatt ttgctttcct ttatcatcgt ttttcgagaa
    15961 agaaaggaaa ctgctcaaac atgggcatgg gtgctcgttt tgatgttcat tccagttgta
    16021 ggatttattt tatatatttt tttaggaaga gggatttcca aagagaaaat ctttgatttg
    16081 aagatccaag ggaaaatcgg taagaacctg gaaattgaag aagacaaaca ggcattgatg
    16141 cgagggcttt atcctcatcc gcctactgga caagtagatg tgaaacaatt gatctatatg
    16201 ctcacggtat ttgaaagtac gctctatacg actaaaaatg aaatcacttt atttacagat
    16261 ggtcgtgaaa aattcgatgc gctgattgaa gatatcaagc aggcagaaga ccatatccac
    16321 ttccagtatt atatttatcg cagtgatgca ttaggtgaag aagttcgaga tgcattgaca
    16381 gaggcggcaa gacgaggggt aaaagtcaga gtccttcttg atgcatgggg ttccacacaa
    16441 gtttcttcca gcttttttca gaatttgaaa aaagcaggcg gagaagtcgc atttttcttt
    16501 cctctatttg ttccgtatat taatcctcgg atcaattatc gcaatcatcg taaaatcgta
    16561 gttattgatg ggaaaatcgg atatacaggt gggttcaatg ttggaaatga atatctagga
    16621 ttggtaaaga aatttggtta ttggcgagac aatcatttgc gtatttacgg agaagcggtg
    16681 tataccttgc aaaaccgttt tttgatggac tggaattctc agcatacaaa agaagtaggc
    16741 tattctccca aattttttcc gtccattcac tctactggtg atatagctgt tcaaatcgtg
    16801 acaagcggac cagataccga acatgaacaa atcaaaatga cttatttgaa aatgatttcg
    16861 ttagccaaac gggagatatt gatccaaacg ccttattaca taccggatgg atcgattcat
    16921 gaagcactga agttggctct tctttcaggc gtaaaagttc atatccaaat acctaacaaa
    16981 ccagatcatc ttctcgttta ctgggcaacg tattctttcg ctgcagagct aatcgagtat
    17041 ggagcaagga tcgaaacata tgagaatgga tttattcatg caaagacgat gattatcgat
    17101 ggtggcattg tttcagttgg ctcagcaaat atcgatgttc gttcatttcg cttggacttt
    17161 gaggtcaata cactggttta tgatgaacga atggcttcac gtgtaagaaa agcttttttt
    17221 gaagactcga aaatttctac gcatctcaca aaagaaatgt atgaaaaccg aggaataatc
    17281 atcaagatga aagaaggatt agcaagattg atttcgccgc tcctttaaaa cataaaaagg
    17341 acatgagaac catcaacaga tggagatctc gtgtcctttt ctaacggggc catttctgag
    17401 agtacgtcag aaatggagaa agcgtctcgc atgagcgaaa ttaactttgg ggtatctctt
    17461 gttttttggg gaaagcaaga aataagctaa tatatgctat taaaagagac acatttcaaa
    17521 gccagtatag catagaaact tttaatgaga tagttttttt tacaattatg agaatttatt
    17581 ttgttattta atgattttga ttcgttttca tcaagtaatg aaaatgataa aataaacata
    17641 ctttaggatt aaaggagatt tctaatgaaa aaacttaaat tattcttacc aataatagga
    17701 ttagctattc ttttatcagg ctgttcaaag tggattgatc gaggagaatc cattacggct
    17761 gttggctctt ctgctttaca gcctttagta gaaacagttg ctgaaactta ccagacagaa
    17821 aatcctggaa aattcatcaa tgtacaaggg ggcggaagcg gaactggttt gtctcaagta
    17881 cagtcaggag cagtcgacat cggaaactct gatttgtttg cggaagaaaa atcggggatc
    17941 gatgcctcag cattagtcga tcatcgagta gcagttgttg ggatcactcc tattgtgaac
    18001 aaggatattg gcgtaaaaga catcagtatg gaaaacctga aaaaactatt tacaggcgag
    18061 atcaaaaact ggagtgaagt cggtggaaaa gatcagccag tagttatatt gaaccgcgct
    18121 tcaggaagcg gaacccgtag cacgtttgaa aaatgggtat tggacggaga aacagctgtt
    18181 caggcacaag aacaagattc aagcggaatg gtgcgccaga tcgttgccga cacacccggt
    18241 gcaatcagct atgttgcttt ttcttatgtt tccgatgatg tagatacgtt gaatgttaac
    18301 ggtgtagaac cgacagatga aaatgtgaca acgaacaaat ggacgatttg ggcatatgag
    18361 catatgtaca caagagatca tccaaaaaaa ctgacaaaag aatttttaga ctatatctta
    18421 tctgatgaag tacaagataa catcgttgga gaactaggtt atatccctgt ttctcatatg
    18481 aaagtcgaac gtgattggca aggaaatatc gttaaagagt aatctttaca caaaatttac
    18541 aaacttagct aaacttttac atgttattaa aaccaaattg atgttcaatt tgtacactga
    18601 gtgagtatgt taaacctgat taagggggag tcatctgtgg aagatgtgaa aaaagtatta
    18661 ttaacaaaat caaaacgttc aaaaatggaa cagcgtggaa aattcatcag ttttttatgt
    18721 atcgcgctga tcgtgttggt tgtattatct attttttatt ttgtagctag taaaggattg
    18781 gccacctttt ttactgataa gatcaatgta tttgattttc tgtttggtac agattggaat
    18841 ccaagccaaa tcggagcaaa tgggaaacca atggtagggg cattgcctat gatcacaggt
    18901 tcgtttattg tgaccttttt atctgctatc gttgccacgc catttgccat tggtgcagca
    18961 gtattcatga cggagatctc tcctaaaaac ggaacgaaga tcttacagcc ggtcatcgag
    19021 ctgcttgtag gtattccttc tgtcgtttat ggttttatcg gtttatcagt tatcgtgcct
    19081 tttgtcagaa gtatttttgg cgggactggg tttggtatct tagctggtac atttgtgttg
    19141 ttcgttatga tcttgccgac tatcacaacg atgactgttg atgcattaaa ggcagtgcca
    19201 cggcactatc gggaagcttc attagcgctt ggtgccacaa gatggcaaac aatctacaaa
    19261 gtcgtgctac gagcagccgt gcccgggatt ttaacagcag tcgtttttgg tatggctcgt
    19321 gcgtttggtg aagccttagc tatccaaatg gtcatcggta atgcagcatt gatgccaaca
    19381 ggtcttacta ctcctgcttc tacattgacg tccatcttaa caatgggaat cggaaataca
    19441 atcatgggaa cagttgaaaa taatgtgtta tggtcattag cgctgatctt gctattgatg
    19501 tcattattct ttaatatcgt gatccgtatg attgggaaga aaggagagct gaaataatga
    19561 acgcaaaacg ctcagataaa attgctacag gtgttttata tatagtttcg gggatcatcg
    19621 tattgatttt agcagcttta ctactttata tcttagttcg gggaataccg cacatttcat
    19681 ggtccttctt gaccgaacct tccaaagcct accaagaagg cggtggaatc gggatccagc
    19741 tatttaactc gatttatttg cttttgatca cgatgatcat cagttttcct atttctttag
    19801 gtgcgggtat ctatctttca gaatatgctg gaaaaaactg gctaacagat gtgattcgca
    19861 cgtcgattga aatcttgagc tcgttgcctt ctgtcgttgt cggtttattc ggtttcttgg
    19921 ttttcgttat tcaattccag tatggtttct cgattatttc tggtgcattg gctttgactg
    19981 tattcaactt gcctcttttg actagaacag ttgaggagtc tttacaagcg gtccattaca
    20041 cacaacgaga agcaggattg gccttaggtt tgtcacgctg ggaaacagtg ataaaagtgg
    20101 tggttccaga agcgacacca gggattttga ctggtgtgat cctaagttct ggaagaattt
    20161 ttggtgaagc agctgcattg atctatacgg ctggacaaag tgcacctgcg ttagatttta
    20221 cgaactggaa tccattaagt gtttcaagcc cgatcagcat tttccgtcaa gctgaaacat
    20281 tagctgtcca tatttggaag atcaatacag aaggcacgat gcctgatggt gtttctgttt
    20341 cggctggcgc ttctgccgtg ttgattattg ctgttttact gttcaacttc ggcgctcgtg
    20401 cgattggcaa acgattatac cgaaaaatga cttcagccta aggagaagaa gcaaaatgaa
    20461 aaaatataac tggaatgaaa caaatgtcat caccatgcca aaagagaaag aagtagcact
    20521 atatacggat gatctacatg tctggtatgg cgacaatgaa gcaatcaaag gagtggatct
    20581 ggaatttgaa aaaaataaga tcactgcact gattggtcct tccggctgcg gaaaatctac
    20641 gtatcttcgt tcgttgaatc gaatgaatga tgggatcgct aatacgaaaa tcactgggaa
    20701 aatcatgtat caaggcgtag atattaatgc gcctcaagtg gatgtttatg agatgcgcaa
    20761 acggattggc atggtttttc aacgtcctaa tccgttcagc aagtcgattt atgacaatat
    20821 tacatttgct ttgaaacagc acggcgaaaa aaacaaaaag aaattagatg aaatcgttga
    20881 aacaagcttg aaacaagctg ccttgtggga ccaagtaaaa gacagcttgg acaaaagtgc
    20941 cttggcttta tctggcgggc aacagcaacg tttatgtatt gctcgtgcga tcgcgatgaa
    21001 acctgatatc ttgctgctag acgagccggc aagtgctttg gaccctattt cgacaggaac
    21061 ggttgaagaa acacttgtaa acttgaaaga agactatacg atcatcatcg tgacgcataa
    21121 catgcaacaa gcagctcgta tcagcgacta tactgccttt ttctatttag gaaaagtaat
    21181 ggaatatgac aaaactaaca agatatttac cagaccaaaa attcaggcaa ccgaagatta
    21241 tgtgtccggt cattttggtt aagacggagg cctcaacatg acaaaagaga ttatttcatc
    21301 taaagatctt catctgtatt atggaaagaa agaagcacta aaagggatcg atctaagctt
    21361 caatcaaggg gaaatcactg cgatgatcgg tccttctggt tgcggaaaat ccacttatct
    21421 gcgttctttg aaccggatga atgacctgat tccgaatgta acgatcaccg gaagtgtttt
    21481 atataaagac aaagacatct atggtccaaa aacagatgtt gttgaactaa gaaaagaaat
    21541 cggcatggta ttccagcagc caaacccatt tcctttttct atctatgaaa atgtcatcta
    21601 tggattgaaa ttaaaagggg aaaaagataa aaaagtcctt gatcaagtag ttgaagaaag
    21661 cctgaaggca gcgtctgttt gggatgatgt gaaagacaaa ttgcataaaa gtgctttatc
    21721 tttatccggt gggcagcagc agcgtgtatg tatcgcacgt gttttggcag ttaatccgga
    21781 aatcatctta ttggatgaac caacaagtgc gcttgatcct gtttctactg ggaaaatcga
    21841 aagtatgctg ttagaattaa gagagcggta tacgatgatc atcgtgaccc ataatatgtc
    21901 tcaagcttca cgtatttcag ataagacggc attcttttta gatggtcact tgatcgaata
    21961 caatgatacg aagaagatat tcatgaatcc agaaaaacaa gagacagaag attatatttc
    22021 aggtcgattt ggataaggag gaaacggaat gctacgtaca caatttgaag aagaattgct
    22081 gaatctccat aatcagttct acgaaatggg gatgatggtg agcagcgccg tgcacaagtc
    22141 agttcgtgca tacatcaaac acgataaaat cttagcccaa gaagttatcg aaaacgatat
    22201 aaatatcaat aacatggaaa cacgcttgga gaagaaaagt tttgaaatga tcgcattgca
    22261 acagccagtt acaactgatt tgcgtatgat cattacggtc atgaaagcta gctcggattt
    22321 agaacgtatg gccgatcatg cggtgtctgt tgctaaatcc acgattcgcg taaaagggca
    22381 gacgagaata ccggaaatcg aaaaagagat ctccgatatg tccgattatg tgaaaaaaat
    22441 ggtggacaac gtcctagttg cttatgtcaa aacagacgaa aaagacgcac gtacgatcgc
    22501 caatatggat caaagagtca atgactattt caatcgaatc tataatgcaa caatcaaaaa
    22561 tatgcaggaa aatcctgaga cagtcatcag tggaacagac tacttgaatg ttgccagtta
    22621 tctagaacgg atcggagact atgtgacaaa catctgtgaa tggatcgtct acttggctac
    22681 agggaaaatc actgagttaa atacgaacca caatgagatt ttctaaactg aagctgtgat
    22741 tatgccgttt gtttaggaaa agaggttgtg aaatcagcgg ttgtgaaaaa gctgttctgc
    22801 atcaagtaat aagaacagtc aaacaaaaaa tagctcctca tatttttcgt ttggctggac
    22861 ttattaccgc agatgcaagc ttttgaacac cgtttattcg ggaaagggtt tgtgacaaaa
    22921 catgtcacaa acccttttca tcatttcata gaaaggataa agaatgcaaa aaaaaattag
    22981 catcatcact atatttttta tttgtgtgct tacttcatgg gttattcagc atcaagccgc
    23041 tttatatgaa gtacctgtca tcgagataga aaaagtacga ataaaagagg atcatcaatt
    23101 gattacagga aaactgatga acacggatca aaaaggagaa tcgatttatt tatcggttcc
    23161 ttatcaaaaa aatcaaatag aaacagcaaa tataaaagcg agacaaatgt atctagtcca
    23221 aatgcatgga gatgaatggc agctagtagc aaaaaaaaat gatggctggc ttttcttctt
    23281 cacaagtatc ttcattggcg ccatgttgct tattggtgga aaacagggtc tatttgcttt
    23341 aggaagtctc atcatcaata tcgttttact tttacttttg ttgctcatct ttactaaaac
    23401 agaagggatt tctctattaa atatatctat cctgttcgtc gttataggga tgattattag
    23461 catattggct ttagatggat ggaatagaag cagtataatc aaaatttcag ctgcagttac
    23521 gagtgttttt ttagcatttt ttatttgtct tttgacaatg aatcattgga aagaccaagg
    23581 actgcgctat gaggaactga attatctgac acgaccgtat cgttctgttt ttctttctag
    23641 cgtactgatt ggaacagctg gaggaacact cgataccgtt atcacagtca ttgcgacatt
    23701 agaagaattg actaagcgac aaccagaaat aacagcgaaa cagttatggc tttcaggaag
    23761 gcaagtgggt cgagatgtga ttggctcgat gaccaatatc cttttgttcg tctatatcag
    23821 tgggtcagtt ccatcgcttc ttttatattt aggaaatcaa tggtcgttca aagaaacgat
    23881 agaacagcat ttatcattgg aatttttacg cgtcattgct ggcagcttag gaatagtatt
    23941 atcgatccct atctcggtcc tcttttttct gactgtaagg aggctgaaac gatgaatgta
    24001 cttattatac ttgttgggat tttagcaatc agcgtgctac ttattggcgg tacgcaaggt
    24061 atgtatattc ttttaggctt attcatcaat ttagggatct ttttcctgtt gttattcggt
    24121 tatcatcaga agtggccgat actggcattg tcggtcatag gatttttatt gattgctgtg
    24181 gttatcttat tttttatcaa cggttataat ctaaaaatgc gtgcagcttt tgtgagtata
    24241 ctgatctttt tattttgttt cctactattg cttcctatca ctgatttttt agcaatccaa
    24301 ggttttacat cggtagaact agaagaatta tctggcttag ataagacttt agcgattgat
    24361 tttagattac ttacgagatc gttgcttctg attagtctta gtggtgctgt tttagatgcg
    24421 agtgtagcaa tttctagtgg gacattcgaa gtatatcagg caaatccgca attatctttt
    24481 taccaattgc gccattctag tttcgctatt gctaaaaaaa tattggcgtc aacagtaatg
    24541 acacttcttt ttgcattcat gggaagttct ttagcgttga tcctctggtt tattgattta
    24601 gacattcctt ttcagcaagt gatcaatgaa aaatcatttg ttctagaata tacgatggct
    24661 attcttacca cattgtccgc actacttgtt cttcctttaa cctgcgtgac tacagcatat
    24721 ctctttacaa aaaagaaaga acaactcaag atggagtaaa agttacaact taagtcctat
    24781 gacattttta ctgaatcagt gcataatatg gatgtaagga aaagcttgca aacaattttg
    24841 cttaaggagg caatttccat gaaagaaaga gaacgtattt tagatttagt gaaaaaagga
    24901 atcctttcga ctgaagaagg cttagattta ttagaaagca tggcaactga aaaagacgaa
    24961 aagcaaatca aaaaagaagc agacaaggta actgctagtc ataaagaaaa agatcaggca
    25021 agtcaattga tcgataaact tgaaaacggc gaagaagaaa tttctgagcc agttgatcca
    25081 aaggaaagag aaagacaaga tcaagaaaac ttagaaaaga tcttagatga actagcaact
    25141 gaagcgaata aaacttcggc gcgtctagat gaagtaaatg ctcaattcgc tgacaataag
    25201 gcagcacgca atgagaaaca ggaagcattg atgcagctga atacaaaaga agaattaggc
    25261 gagttgacag aagaagaatt agcacagcgt cagacgttag aagcagaaat caaagaatta
    25321 gaagctagtg gcgatacact gttagaagaa caattgaaat tagaagcaga attaaaagat
    25381 atccgtaaga atcaatggtc tgagaaaaaa gaaacgttta ctgataagtt tgaattgcca
    25441 gatgattgga aagatcaagc aacagataca ctgaatcaag taggcgaaaa aatgtcagaa
    25501 gctggatcac agttaggcaa attcttgaag aaaacattcc aaactgtttc agaaacagtg
    25561 aatgacaaca tggaatggaa agatgtcagc ttacgtgtcc ctgggattgc gacaacgaaa
    25621 tttgagcatg aattttacta tgaagctcct gcagcaagta tccttgatat caaggcagca
    25681 aacggaaacg tgacgttaaa aacgtgggac agcaacgatg tgaaagttga agctaagatc
    25741 aaactttacg gaaaaatggg tgctgaacca tttgaagcat tctctgaacg gagccagatt
    25801 gaggttaatg aagatcatat ctccttccaa attccaaata aacgtgtgcg tgcagacctt
    25861 gttttctact tacctaaacg agtatacgac cacgcagcta ttaaacttct aaatggcaac
    25921 atcatgattg aaacattgga agctaaagat atttatacaa aatctacgaa tggtaacatc
    25981 atcgtggacc aattaactgc aacgatgctg gaagtagaag gtgtaaacgg caatatcgat
    26041 attcgaaacg ggaacatctt agattctatt atcgaaacag taaatggtac agtgacattt
    26101 ggtgcgacag cagaaaacct ttctgtgtct ttggtaaatg gtgatgtacg tcttacgatt
    26161 aaagaagata atttgaaaaa agtagaagca agttcagtga acggaaatgt caaagtcgct
    26221 ttaccagatg gcatcggttt ggaaggacat gctaaaacaa gtcttggaag tatcaacagc
    26281 cgtctgtcca attacgaagt agttcgtgag aaaaaagaac ggacaaacca aatgttgcaa
    26341 ttccgtcgtg tttcagatgg tgaaatcgcg caagtgcaac tttcaacgac aacaggaagt
    26401 atctatttaa aagatacaga taaataaaga ggttgtgaaa gagatgttca gccttgagca
    26461 ataagaagcg attttgtaaa atagcttccc ctattttaca aaattgtgcc ttattgccga
    26521 tagtctatct cttgaacacc gtttaccaag agattatgaa cctgccaatt atcgccgagt
    26581 cacaaggaat aatttcagaa aaagctcgtc acgttttatg aatatggtaa tttgtgaccg
    26641 agaattttgc agaaagacac cgattaagaa gaaggttgtc acaacgattt tcttcattta
    26701 aaatagtaga acagaggtga gacatgatga aaaaaaagtt gacaaaatct aataaaaatg
    26761 ttgttttgac agggacttta gcaggaatag gagaatacat cgggattgat ccgactgtta
    26821 tccgtgtgct ttatgtattc ctgagcttag ttgcttttgg aagtccaatt attttataca
    26881 ttttattagc tttgattatc ccatttgcgc gttctgcacg aacaaactat ggacataaca
    26941 atgcatatta tgaaaaaaac aattatcgtg aacaaactcg tgaacaaaca aaaaaacgca
    27001 aagaagcgga aaaaatcgat gatgacgaat ggagtgactt ttaatgtcgt actttcaacg
    27061 tattttagtt aatacgttaa cattcatatc attggctgtt ctttttcctg cgatggtcca
    27121 tgtgagcagt atttggacgg ccgttcttgc cagcttcgta ttgtctgtgt tgaatatgtt
    27181 tgtcaaaccg attttgacga tactgtccct gccctttaca ttagtcacat tgggattgtt
    27241 tacgtttgtt atcaatgcag cgattcttaa aatgacctcc ttttttgtgg gagcagaaca
    27301 ttttagtttt tcttcattcg gtgcagcgtt gttagtagct atcttgatgt cgcttgtcaa
    27361 tgtaattgtc agcgaacata acagtagaaa ataaaagaaa gctgtgccga actatcggcg
    27421 cagttttttt atttagaatc aggaatgcgt tttctattac attggtaatt aaataaaaac
    27481 gtttttttta attggtagta cttttggcta gacaatgata aaatgataga gaacactcta
    27541 atagaaatga ggtagcatga atgtcagaag ttgtaaaagt tagccaatta gtgaaaaaat
    27601 tatctttgga aatcgtgaca ggcgacgaga aaagcttaga ccgtgtcatc gtaactgggg
    27661 acatctcacg cccaggacta gagttgactg gttattttaa ttattattcc cataatcgtt
    27721 tacagctatt tggcagtaaa gaaatcagtt ttgcggaacg gatgatccca gaagagcgtt
    27781 tgatcatcat gagaagatta tgtagtgaag atatgcccgc atttattatt tcaagaggat
    27841 taccagctcc agaagaaatg atccaggcag caaataaaaa tgggatagct gtactgcgtt
    27901 ctcccatctc aacttctcgt ttattaggag aattatccag ttatttagat ggtcgccttg
    27961 cccctcgaac aagtgtccac ggtgttttag tggatgttta cggattaggt gtactgattc
    28021 aaggtgacag tgggatagga aaaagtgaaa cagcgttgga gttgatcaaa cgcggccatc
    28081 gattgatcgc agacgatcga gtagatgttt atcagcaaga tgaattaacg gtgatcggag
    28141 aaccgcctaa aatcctggaa catctgattg aaatccgagg aatcgggatc attgatgtaa
    28201 tgaatctttt tggtgcgagt gcggtacgtg gctctatgca agtccagttg gctgtttatc
    28261 tggaagcatg ggcaaaagat aagaaatacg accgtctggg ctctgaagac acgaccgttg
    28321 aaatcgcgga agtgggcatt ccacaaataa aaatccctgt caaaacagga cgaaacgttg
    28381 caatcatcat tgaagtagcc gcgatgaatt tccgtgcacg tacaatgggc tttgacgcaa
    28441 cgaaaacatt tgaagaaaga ttaagtcgct tgattgaaga aaactcaggc aacgactagc
    28501 aaggagtgac aatatgttag cacaaatcaa tcgagttgct tttgagcttg tagggattcc
    28561 tatctactgg tatgcattga tcatcgtatc aggtatcatt atcgctatgt ggcttagcag
    28621 cagagaggct gttcgggtag gattaaaagc agatgatgtg acagatttta tgttgtgggg
    28681 attgcctatc tccattattg gcgctcgctt atattatgtt ttatttgatc ttccccagta
    28741 tatagctgat ccaatccaaa tattcaatat ccgttcagga ggcttagcta tttatggcgg
    28801 actgattgca ggcgcgatca cgctgtattt ttttactaaa tatcatttta tttctttgtg
    28861 gactttttta gatatcgctg caccaagtgt attattagca caggcaatcg gtcgttgggg
    28921 aaatttcatg aaccacgaag catatggacc agacacgacg cgaagcttct tagaaagtct
    28981 gcatttaccg caattcatca ttgataatat gtatatcgaa gggatctatc gtcaaccaac
    29041 atttctttat gaatcacttt ggagtttgat tggatttatt ttgcttttgt ttttacgaaa
    29101 gaaaccacac cttttgaaaa aaggcgaagt ccttttatgt tatctaatgt ggtatagttt
    29161 cgggcgtttc tttattgaag gattacgtac agacagtctt tactttttag gtgtgatccg
    29221 tatttctcaa ttattatctg ctgtgttatt tgtcggtaca ttgattctat ttatttggcg
    29281 cagaaaaaaa ggaaatttac cggattatga ccgctcatta ggaaaaaatc aacaaattat
    29341 ctgattttta gagcgttaaa aatgaaaaaa atttcaggag tggtaaaatg aattatagag
    29401 tagcggtttt aggaccaggc tcttggggta ctgctttggc acaagtcctc gccgaaaacg
    29461 gacatgacgt tcggatttgg ggacatcgtg cttcacaagt agaagaaatc aacacccaac
    29521 acacgaatca acgttattta ccagatcatt atctacccga ttccatccaa gcattcacca
    29581 atatggaaga tgcagtaaaa gacgcagatg cggtgctatt cgtcattcca acgaaagcaa
    29641 tacgttctgt tgcaaaagaa ctagtgccta aattgaatac aaagccagtg atcatccatg
    29701 caagtaaagg attagaacag ggaacacata aaaggatctc tgacatcttg ttagaggaaa
    29761 tcccagcaga aaaaagaaaa gctgttgttg ttctttctgg accaagccat gcagaagaag
    29821 tagcaaaaca tgacatcact acgatcacag ctgcaagtac agatgcaaaa gcagcaaaat
    29881 atgtacaaga gctgttcatg aataattatt ttcggatcta taccaatcct gatgtgatcg
    29941 gtgtagagat gggggcagct ttgaaaaata ttattgctat tggtgctggc gctattcacg
    30001 gcttagggtt tggcgataat gcaaaggcag caatcatgac gcgcggatta gctgagatca
    30061 gccgtttagg tgtagcaatg ggtgccaacc cgctgacctt tatcggatta agcggaatag
    30121 gcgatctagt cgttacttgc acaagtgttc attctaggaa ctggcgcgca ggcaacttgt
    30181 taggacaagg gcagccccta gaagaggtgc tagccaatat gggaatggtc gttgaaggtg
    30241 tgaatactac ccaagcagcg atggaactag cccaaatgat ggaaatcgaa atgcccatca
    30301 ctcaaacaat ctatgaagtg ctgtatgaac aaaaagaaat caaaacagcc gcaaaagaaa
    30361 tcatgttacg tgatggaaaa aaagaaaatg aattctcatt aacaattttt tgaaggagcg
    30421 aatgtatatg aaagttaaaa aagcagttat tccagcagca ggattaggaa caagattttt
    30481 accagcaaca aaagctatgg caaaggaaat gttgccaatt gttgataaac caacaatcca
    30541 gttcatcgtt gaagaagcgt tgaaatcagg tatcgaagac atcttgatcg ttacaggaaa
    30601 agctaaacga ccaatcgaag atcactttga ttcaaatatt gaattagaaa caaacctaag
    30661 tgaaaaagga aagaccgaat tattgaaatt agtagaagaa acgacagatg tcaacttgca
    30721 tttcatccgt caatctcatc caaagggttt aggacatgcc gttcttcaag caagagcctt
    30781 tattggaaat gaaccatttg tcgttatgct aggcgatgat ataatggaag acgaagtacc
    30841 attgacacag caattaatcg atgattacga acgtactcat gcttctacga tcgccgttat
    30901 gcaagttcct catgatgaaa cttcaaaata cggaattatc aatccaggag aagtattgga
    30961 agatgggtta tacaatgtca aaaactttgt tgaaaaacca gatccaagca aagcaccaag
    31021 tgatttagct attattggac gttacttatt gactccagaa atttttgatg tattgtccga
    31081 gcaacaacca ggagccggaa atgaaatcca actaactgac gcaatcgata cattgaataa
    31141 aacacaacgc gtatttgccc gtaaattcac aggtaaacgt tacgatgtcg gtgacaaatt
    31201 tggttttatg aaaacaagta ttgaatatgg tctaacacat ccagaagtag gtgcaccttt
    31261 acgtgagtac atcctgtctt taggtaaaac attagaagca gaaggaagca agatcgatca
    31321 taatccaaaa ggaataacag aaatcaaaga agaaaagaaa aaataaccct tttttctaac
    31381 gagcttcagc tgctaattga ataaaaagta gttgaagctc gtttttattt gtttaaaaaa
    31441 cacgaaaatg ctatccttat agaaaagaga gacaagaagg gagtttgatc atgtcaggag
    31501 gagaaattgc aggattgatc gcagcaatcg cctttgcgat acttgtcgtt tttatcgttc
    31561 gtgtgttgtt gcaagtttct aaaactttag aaaaagtaga tcagactgta gcagaagcaa
    31621 atacgacgat cgaaatcgtc acaaaagacg tagatctttt gtctagacaa gtagaaggct
    31681 tactggtcaa aagtaatgaa ctgctcttgg atatcaatgg aaaagtcgca acgatcgatc
    31741 cattgttcac agcagttgct gatttaagtg aaagtgtatc agaacttaat cattctagta
    31801 aaaacatcgc gacgaaagtc ggcggaatcg gtaaaacgac agctaaagcg acggttgccg
    31861 gaaaagtcgg tgggacagcg atgaaatttt ttaaaaacaa aaaacatact gaaacgacag
    31921 gaggaaaata aaaatggcta aaaaaggtgg atttttatta ggtgcagtag tcggaggcac
    31981 agccgcagca atcgccgcgt tattgttagc accaaaatct ggtaaagaac ttcgggatga
    32041 attagctgcc caagcggatg atttgatgga tatggcttca gattacacag atatggcgaa
    32101 agaaaaatcg actgagttaa caggtattgc aaaagaaaaa gcgcaagatc tttctcaaca
    32161 agcaggtgat ctagcaggta gtgtcaaaca aaaagtaagt gaatcagcag atgaagcagg
    32221 aagtgaatct gacgatatct tgttaaatct taaagaacaa tcagctgact tatctaatcg
    32281 tttcaaaaaa acggcagaag atatgaaaaa acctgcagat gaattaggaa gtattgctaa
    32341 agatacttca gaagatatca tgattgatgt aaaagacgct gctggtaaag caggagatac
    32401 tgtcaatgaa ggaatgtcag aagcaaaacc agttgcagat gactcaaaag aaatgatgaa
    32461 aatggcaaaa gaagatgcga aagaagctaa aaaagaaata aaagatacaa tgacagattc
    32521 atctacaaat cactaaaatc acaaatttat agaataaaaa ggtgggagcg gactagctct
    32581 cacctttttt actcttattt ttctaaaaca agtaattctt ttggtgtagt cgtgaatggc
    32641 acacagccat cgcttgtcac atatacacag tcttcgatac gtacccctac tttttcagga
    32701 atatagattc ctggttcaag agagaagcac atcccttctt cgattactaa gtcatttcct
    32761 tctacaaggg aagggaattc gtggacggtt gttccgatcc cgtgacctaa acggtgattg
    32821 aaatattcgc cgtagccata gctgttgatc acgtttcgtg cgatttgatc aagttcacct
    32881 gctgtcacac ctggacggac ggcttcttgt gcggcaagct gtgcttcaag agtgatgttg
    32941 tagatttttt cttggaagtc ggttggtttt tgataagcaa ttgtacgagt agcatcactg
    33001 caatagccat tccaaacaac gccaagatcg aataacacaa gttcattcgg tgaaatcttc
    33061 gtatttcctg gtgtaccatg agggcttgca gcatttgctc ctgcaaggac taatgtgtcg
    33121 aaagacattt gtgaaacacc ttgttttttc aattggtatt caatttctgc aatgatcgct
    33181 tgttcagtca cgccttcttt cactgcttta aagccaatct caaatgcaac atcggcccat
    33241 ttaccagctt cgatcagttt gtctttttcc tctagagttt tgatcagttg tagacgttgg
    33301 atgatggaag ttagatcagt gtaagaatcc gttcccgtca agatatcaga gatagcatcg
    33361 aagcgctcga cagtcaaggc gttcttttca atccctacat tgccaggctg accatagcga
    33421 gcacgaagtt cttttccgat gatctcccaa gggttttcgc tgtctaaata gccacggaca
    33481 tcatacgccc aactactgtt ttgagcatct tcaacttcca aagcaggagt gaaaaggaaa
    33541 ggatcttgtt caagagggat aaaaagagct agtacacgct catgaggatc actttcgtat
    33601 ccggaaaagt aagcgatgtg gccagggtcg ctgatataag ccaattcgac ttggtgttgt
    33661 gccatccatt gacgtagttc attgattttt acgttattca tttggcaacc tactttctaa
    33721 attaattttg tattcaataa ttgtaccact gatttattaa aagaccaacg ttctaaaaac
    33781 tgaaaaaagt aaaaattttc atgaaaacag agataaaacg gttgcaattc ttgagattat
    33841 ttgatattct attttagaaa tgtaagacgt attttcagaa aacatataaa atatgaatag
    33901 gagaacacaa atggaaaagc aaacaatcac tatctatgat gtagcgagag aggcaaatgt
    33961 ttcgatggct actgtttcac gtgtcgtaaa tggcaatcca aacgttaaac cagcaacaag
    34021 aaaaaaagtc ttggaagtta tcgatcgctt ggattatcgt ccaaacgcag ttgcgcgtgg
    34081 cttggcaagt aagaaaacaa caacagttgg tgtaatcatc cctgatgtca gcaatatgtt
    34141 ctttgcttct ttagcacgtg gtatcgatga tgtggcaaca atgtacaaat acaatattat
    34201 cttagcaaat tcagatggca acgaccaaaa agaagtcaat gtattgaata acttactggc
    34261 taagcaagtg gacggcgtga tcttcatggg tcaccatatc acagacgaaa tccgtggaga
    34321 attttcacgt tcaaaaactc ctgttgtatt agctggctct attgatccag atgaacaagt
    34381 aggtagcgta aacattgatt atgtatccgc aacaaaagat gcagtaaaca aattggcaaa
    34441 aagcggcaat aaaaaaatcg cttttgtcag tggtgcgttg atcgatccca tcaatggaca
    34501 aaatcgtctg aaaggctata aagaagcatt aagcgaaaat aacctaccat atagcgaagg
    34561 attgatcttt gaagcacaat acaacttcaa agatggtcta tctctagtcg atcggatcca
    34621 taatagcggt gcaacagctg tctatgtttc agatgatgaa ttagccatcg gtattttgga
    34681 tggtttatta gaccgtggcg tgaaagtacc ggaagaattc gaaatcatca caagtaacaa
    34741 ttcactactg acagaagtag ctcgtcctcg tttaacaagt atcacacaac cattatacga
    34801 tttaggggcg gtatctatgc gcctattgac gaaaatgatg aataaagaag aagtcgaaga
    34861 aaaaacgatt atcttgcctt atggaatcga agaaaaagga tctacaaaat aataaaagga
    34921 caaccattca gaggttgtgt gcctgccgtt taactctgcg ttacaaggag caatttcaaa
    34981 aaacagcatc tcatgtttga tgaatattgt gactcgtgat tcggagttgg caggagaaca
    35041 ccgtttattt gggaaaaggg gttatgacaa aattttgtta taatcctttt tttgtgtctt
    35101 aaaaaagaga gaaagtggtt gaaattacat ttatcgtata taaaacaatc cgtgtataga
    35161 tgctgcattt tgttcaccac catcaaaaaa ataagggact gtgacaatac tattgtcaca
    35221 atcccttatt actgtgtatt ctattaaatc aatcatcttt ctcatctgat tctttagttg
    35281 cttgattcgc tcttgcataa gctgaagcgg tgttccagta atctgtatag ttttcatcgg
    35341 taccgccaac gccaaattta aaggcgcttt tcttcggtcc atttttcgcc catagcgatt
    35401 caactgtttt tcctggtgtt tggatggatt ttttattgac agtaactttt ccaggtgttt
    35461 gaccagtaaa tccagatact tttttcttca tcacatcaga tgataattcg aatttctcat
    35521 cagtgccaaa aatgtcaggt tttgcttggt aagcttgatt gatcagattg gcaagataat
    35581 tagccgaacg tatccttgct ttgctgtcca ttccagtatt gtcatcgtgc cctgcccagc
    35641 tactgatggt aatagacgga gtagagacaa ttagccatga atctcggtat tcattggtag
    35701 aaccagtttt tccgacccaa tctgcttttc ctagatttcc gtttaagctt gagatggcat
    35761 ctttgaatgg tgtagtgatt tttgcattga tcacactacg catcatgtca ttcatgatcg
    35821 atgccgttgc ttccgaatag atccggacag agttgctttc gtgtttataa attacatttc
    35881 ctgcgttatc tgtgatggaa tcgatgatat agccttcttc atagacgccg ccgtttgcta
    35941 aagcctgaaa tccgttggtc tgttgaagcg tcgtgacatc tactgtacct aaaggagcag
    36001 attcaacgcc ccaattgtca tttgccgggt agttcatctt tgccaagtag tgctcgtaag
    36061 catattgttt cgatccaccg gaattcaaca catcttgata taagtgataa gccgggatat
    36121 tgttggacca ttctagtgac tcacggacgg tttggaaggt gttcgatcct tcgttagtag
    36181 cattgacgat tttctcgcca gcattttctc cttcttgcca agttgttgca taatctgata
    36241 cacgggattc tgatccgata agccccatgt cgattgcagg tccataaaca agaactggtt
    36301 tgattgatga gccagcttga cgttctgtat cgaaggcatg gttattttga ttctgactgt
    36361 aattccgtcc gccaacgaat ccgtagatgc ggccagttct gttatccatc aatacatttc
    36421 cggtttctac ttgactgcca gcaccatcat ctaacatgta tccataattt tcaacgccat
    36481 tttgcaatgc agcatagaca tctttatcga ttgtcgaatg gattgtatat cctttatttt
    36541 ggatcgtttg ctgtgccttt tgataataag cgtcactgac cgatgaatca gacatatcag
    36601 cgttgtcttt ttcagccaat tgttgtgcaa tgattcttgt tgcttcattc atcacagtat
    36661 aatacaagaa ttctctgtca gtctgttctg cgatttgttg tggtagaaag tcttttgtaa
    36721 ggtcataggc ttttgcttct tcgtattgtt ctttcgtaat ttggccttca cgatacatac
    36781 tgaataaaac aaaatctttt ctggcaaggc cggcagaaag atcttctttt agcgcgcctg
    36841 tgttcgtgta tggactatac gtgatcgggc tttggggtaa tccagcgata taagcagctt
    36901 gcggcagcgt cacatctttt gcatctacac caaagattcc ttttgcagct tcctggactc
    36961 cagcaatgtt ttgtccctta ttattacgac caaatggtga gacattcaaa tacgtagcaa
    37021 tgatctcatc ttttgaaaag tatttttcta cttgtgcaga aagaatgatc tcgtttgctt
    37081 tacgtttgaa tgttgtttca tctgtaagga tctgctgttt gactaattgc tgtgtcaaag
    37141 ttgatccacc agaagagcca ataccagtag cttcagatac taatgctcgt aaaacagctt
    37201 taggaacgta accttggtgt ttatcgaagt attcatcctc tgtgctgata attgcagttt
    37261 tcaataaagg tgaaatctta tcagatgaaa tagtcgtgcg catcagatct gtctggattt
    37321 ttgatatctc tgtattatct gcataaacaa tctttgacgt ttctgtaatg tttcctagtt
    37381 ctgtctgcag tgctttttta gtcggcaatt gtgtgtcttc gacgagatag gcaaaatagc
    37441 cagcgcctat tccaatacct agagctgcga acatcaaaag aagaacagta ataaaaacag
    37501 tcaatgattg aaaaactcta aaaataatct taggaacaaa ccatttttct ttttttcttc
    37561 tattctgttt ttttcgagta tttttgcgtg gcaaaagggt cacctcaact aatggtttta
    37621 tttcgctaat tatagcaaat aatagaacaa aaaaacagac aaggctgttt ttggcaggaa
    37681 tttctttttt aaaagagtta aaacgtgaga aaatgatctt tattataaaa gagttcttaa
    37741 gcttttcttt agagaaaatt tcagttacta tggagaacag ggcaaagaaa aatcaatcat
    37801 tttctttgta tatcatctta ccaatatata ggaattgtta gtaacaattg cctttcaagg
    37861 aggaatccat ccatgttatt aggctcacac gtcagcatga gcggaaagaa aatgctgtta
    37921 ggagcagcag cagaagcagc cagttatgga tcttcgactt ttatgatcta tacaggcgcc
    37981 cctcaaaaca ctagaagaaa agccatcgaa gagatgaata ttgatgccgg aaaagcgtac
    38041 atggcagaaa acggtctaac aaatatcgtc gttcatgccc cttatatcat taatttgggg
    38101 aatacgatca aaccagaaat gtttcctttt gccgtccaat ttctgagaga agagattgtt
    38161 cgtgcggaag ctttaggcgc tactcaaatt acacttcacc caggtgctca tgtaggggca
    38221 ggaacagaag ccggaattgc tagaattatt gaaggcttga atgaagtttt gacaaaagaa
    38281 cagacggcac aaatcgcttt ggagacaatg gcaggtaaag gtacggaaat cggtcgaaca
    38341 tttgaggaat tagcgcaaat catcgatgga gtaaaattaa atgaaaaatt atccgttact
    38401 tttgacacct gtcatacgaa tgatgccggt tataatatta aagaagactt ttcaggtgta
    38461 atggaagagt ttgataagat catcgggtta gatcggctta aagtactcca tatcaatgat
    38521 tctaaaaatc cgcaaggttc gcataaagac cggcacgcca atattggttt tggaacaatc
    38581 ggattcgaca cgctgaataa gatcgtccat gatccaatgt ttgacaatat ttcgaaaatc
    38641 ttggaaactc cctatgtcgg caaagataaa aagaaagctt acgcaccata tggaaaagaa
    38701 atcgccatgt tcaaagcaca aatattcgat ccagaagtgt ttcctgagtt attagcagaa
    38761 gaagtgatac tctaagattt tctatctgac agcagcaaaa aaggaccagg cacattgcct
    38821 tgtccttttt tgtttaagaa acaaaggagt actttttgca gtctttttca tcatgcatct
    38881 tctcccccct ctttttaaat ttagacaaac aaggtatact gttagaaaag taaaaaaacg
    38941 aaaagtttca caagcaagtg gcaaaacgtg attggaagga cgaaaagatg ctgaacactt
    39001 taaaaccctt gatcaaccaa ctaaaaaaga aacatacata ctttattctt ggcatagccc
    39061 tattatttac aattattcgt ttgtatttat atagtaaagc aatctatgga acagacatgt
    39121 cggcaaccta tgatgaccag ctgctgattc gctatgctca aaatattttg gacggtaaat
    39181 ggctagggga gtatacgact acaacacttt ccaaaggaat ctcctacagc ttatttttag
    39241 tacttgcaca taaactgcat ctttcttatg ctgttttgtt cggcatgttc agtatttttg
    39301 ccagtatatt ggttgcactc gcgtttaaac cgatcgtgaa gaacaagtat cttcttttaa
    39361 gtatctattt ttattttttg ttttctccga ttagttttac acatgaatat tccactcgaa
    39421 catatcgtaa tgccctcgtg attccggctg ttgagatcat tatcgcttgt ttactagcta
    39481 tttattaccg caaatacggt tctagcagaa aattgctgcc atggttttta gggctttctg
    39541 tcgcttttcc tttcttttgg ttcattcgcg aagattctat ctggcttctt ccttttactg
    39601 tagtagcttt gggtatcagt ttcgtccaga tcttgctagg gcaagacttt tctttcaaag
    39661 aagtaaagaa gttaaaaaaa cgactctttc ttctctcgaa acgggaatgg ctgaaacttt
    39721 cattgttttt acttcctata gttggctttt ccatcgtcta tcagtggatc gaatataaaa
    39781 atgagacaac atacggtatt gcaaccatca atgaccgttc cagtggagaa tttggacgtt
    39841 tgatgaaaca actgatccga atagatgatg aaacgaactt gaataaagaa aacagtgaga
    39901 tatgggtctc acatgctgca ctaaataaag cattagccgc atctcctaca ttccatactg
    39961 tttctacccg tattgacgaa ttatatacga ctcacgcgtg gactcaaggt ggaaaagtaa
    40021 aagaattacc cggagatatc atcttttggg cattgcgaga tgtggtaagc gaatctggtt
    40081 attaccaaaa caatgcaaaa gaaaccaatg atttttggaa aaaagtcaac caagaattag
    40141 aagaagccta tcacaaggga accatcaaaa agaaaaaaga gttctatctg atgggatcag
    40201 gagatggaaa gacgatgagt gatctgccaa tcgtattcga tttccttcaa tcaggatacg
    40261 cttatgcatg gcgatataaa gatttccatc aaggaggaaa ttatagtttc ggaacgcaag
    40321 aacaagtcaa acaggctcaa gaattattaa accttccgct aatggagaat tggatcgata
    40381 gtaatgaacc gagaacacct aatttccaat taacaaaatc agcaaaagtc gcgaatgtca
    40441 tcataaaaat ttaccaagtt ctggctattc ccgtgctgat tgcttcaata gcagggatat
    40501 tacttatgat actaggaacc gtatttgcaa aagctgatcg tgcctattat agttcctctt
    40561 tgattgtggt caccggatta atactgacac aattggtttt tcttttcggt gtctcgtggt
    40621 tttgttctta tgcgccagaa aaaaaggatt attttttaag tgtctacact ggcgcaggcg
    40681 tgccattaac gcaattcatc gtagtaacaa gcatgctagt tttcagtaaa ttaaatctga
    40741 aaaaggcttt atcttctaaa taaaaagacc cttggtagct agatttttaa cctaactatc
    40801 aagggtcttt gtgtggaaaa atcagtttct attcgatttc ttctaccgtt tcctgcaaac
    40861 gctgttcata ttttttgttt cctttatata aatcaccaat cgtccatgcc aacaggagaa
    40921 ggacaagaac aatgattaca taagcgatgt gatcagccaa tgctagttga gcagaagtgg
    40981 cttgttcacc aaagaaactt tcgatctgtc ctggtaatcc tcgtaagttc aagtaagtta
    41041 gactaatcac agagaaccag ccaagaagtt ttacgatgaa tgaattttta aatcggctac
    41101 ccatctccgc ttggctgttg gtcatcatca gtaaagggat catcgaaaac ggcaacgcaa
    41161 aagccaagaa cacctgggat tcattcatca agttattcaa agcggtatgt tcttcgatcg
    41221 ttccttttgt acttgtaaac aaaacacaaa tcaatacagg aatcacagaa agcaatcgtg
    41281 tgaccagtct tcttagccaa atcgggatac gcatatggat gaagccttcc atgatgactt
    41341 gaccggtcaa cgtaccagta atagtagagt tctggccaga agcaagaagt gctacagcaa
    41401 ataaagtgga taagatacca gattttgcta cagcaatcaa gataccattg ctcatagctg
    41461 atggatcaga taaggcttca tacagaccaa aaaaggaagg atcttggaca gaaccggttt
    41521 tgaagacagc gacacccatg atcaatagca gtgcattgac tagaaaagcc atcgacaatt
    41581 ggatattaga gtcccaagta gaaaaacgta cagcttgtgc tacatcttct tcgtcttggt
    41641 gatcaatctt ccgagtttga gaaactgctg aatgaagata taagttatgc ggcatgactg
    41701 ttgcaccaat aatccctaaa gctccagtca gcggagtttc gccgccgatg accggtgagt
    41761 ctgagaatgt atgactgtta gggataaagc cagcaaataa actgtgccaa tctgggttag
    41821 acaagccaac ttgatagaca aaaacgaata aaatgacgaa aattaagcag acaaccagtg
    41881 cttcgatctt acgaaacccg acttttgtca gtagtaagag aacgaaaaca tctaatacag
    41941 taataaagac ggcaatcacc aatggaatat caaaaagtaa gtagagggcg attgctgcac
    42001 caatgacttc tgcgatgtct gttgccataa tggctaattc agtcaagatc cataaaatga
    42061 cacccaatgt cttacttgtg cgtgctcgga ttgcttgggc caaatccatt tgggtcacga
    42121 ttcctaattt tgctgccata tactgtaaaa gcatagcaat cagactagac atcaaaataa
    42181 ctgacatcaa taaatattgg aaattttgtc caccagtgat cgaagtggac cagttacctg
    42241 gatccatata accaactgct actaatgcac ctggtccaga gtaagcaaga agtgttttaa
    42301 aaaaactttt cccctttggt acatcaactg ttccatttac ttcagctaaa gataaaccat
    42361 ttgtatgttc aataagtcga tgcttatgaa attgtttgtt ggattgatta ttcaagaaaa
    42421 aaccaccttt cctatttatc tacgattaca ttctacacct caaaaagaaa aaattaaaga
    42481 aaaatattcg gtatgcctaa tttattttcg tggcgcgtct tgttagatga cgaaagaaat
    42541 tttgttctcc tctaaaaaaa ccactatttt ttgcatgaaa ctaaagaata cgcctttctt
    42601 ttttcaataa actttagtaa aataagtcat tgagagcaat tcggaaatag aaaggagaga
    42661 tttatatgtt atcaacaggt attgtcgtac ttattgctat tattgctttg ctaatcggcg
    42721 cagtaggtgg ctttttccta gcgcgtaaat atatgaaaga ctatttagaa aaaaatcctc
    42781 ccgttaatga ggacatgttg cgatcaatga tgatgtcaat gggacaaaaa ccatctgaga
    42841 agaaaattcg ccagatgatg cagcaaatga agaaccaagg gaaaaaatag gttctgaccc
    42901 aacgactttt tacgggctga ttttttcagt ccgtttttta ttttgtaatt tgttagacta
    42961 ttcagattat tcagcaaaaa gacaagcaca gacaatccta ggctcttgat aaagacaaag
    43021 gaggagtaaa atgtcgattt ttagaaagtt aggctggttt tttcgtcagg aaaagaaaca
    43081 ttatttaatt ggggttttct cgctattcgc agtggccttg gtacagttag ttcctccaaa
    43141 agtgattggg atcatcattg atgagattgc cgataaaaat ttatcagtaa agatcatttt
    43201 cgggtggatc ttcctattga ttatcgctgc tttcttacaa tatctttttc gttatatctg
    43261 gcggacgaat atttggggaa gtgcagctcg gttggagaaa gaacttcggc agcagttatt
    43321 caaacatttt acaaaaatgg acaatctctt ttaccaaaaa tatcggactg gggatttgat
    43381 ggctcatgca acgaatgatt tgaatgcgat ccagaatgta gcaggagctg gtatcttgac
    43441 ctttgcagat tcagtgatta cgggcggaac aacgatcatt gtgatgattt tgtttattga
    43501 ttggcgctta acactgattg cgctgattcc tctgcctttg ctggccgtca cttcacgagt
    43561 gctggggtcg aaactccatg atgcttttcg tgattcgcaa gaagcttttt ctagtatcaa
    43621 tgataagaca caagaaagta tcactgggat caaagtcatt aaaacatttg gacaagaaaa
    43681 agaagatcta gcggattttg aagaaaagat tgaagatgca attattaaaa acaaacgagt
    43741 caattttcta gactccttat ttgatccatt cattaccttg attatcggtc tgtcttatgt
    43801 tgcaacaatt attttaggtg gaaagtatgt cttggaaggc acgatctcga tcgggcagat
    43861 ggtctcattt attagttata tcggtatgct tgtttggccg atgtttgcga ttggtcgatt
    43921 gttcaacgta ttggaaagag gaaatgcttc ttatgatcgc gtcaatgaac ttttgcatga
    43981 aaaaacgcat atcgtggaac aactgggtgc agtgcagacc ccggtaaaag gcgagctgaa
    44041 tgtagctatt tcctctttta attatccgaa agaagaatca ccagcattag aacaaatcaa
    44101 gtttgcaatc caagaaggag aaacattagg tattgttggg aaaactggtg cgggaaaaac
    44161 aacgatcatc aaattactga tgcgtgaata cgatgattat caagggaaaa tccaatttgg
    44221 cggacgttcg atcaaagaat attcattgaa tgctttatta ggatcaatcg gctatgtgcc
    44281 tcaggatcac ttcttgtttt cgatgaccat tcgagataat atccgttttt ctaatccaaa
    44341 actttcagaa gaagaagtag agcatgcggc ttctttagca tttatcaaca atgaaatcaa
    44401 ggaattacca aaaggttatg ataccttagt tggagaacgt ggagtctctt tatctggcgg
    44461 acagaaacaa aggatttcga ttgctcgagc attgatcaaa aatcctgaat tattaatatt
    44521 agatgatgca ctttctgcag tagatgccaa aacagaagaa gctatcttgc ataatttaaa
    44581 agaaataaga aaagagaaaa caactatcat tgcagctcac cgtttaagta gcgtgatgca
    44641 tgcaaaagaa atcattgttg tcgatcaagg gaaaatcatt gaacgaggaa cccatcatga
    44701 gctgcttgca ctaggcggct ggtatgaaca aatgtgggag aaacagcaat tagaagcgaa
    44761 gatagaagga ggcgaggcct gatggatgaa aattatcaat cggaatggac aaaatcgatt
    44821 ccacttaaag aacagaaaaa gatcatcaaa cgactgatga agttcgccaa accttttaga
    44881 acaacgttca tcgttgctat cttatttgcg tttgctctgt ctgtgatcaa tgtcctattg
    44941 ccaaggatca tccaaacttt tatggatgat catctggcta aacagtcggc tacgacacaa
    45001 gttattttgt tttttgctgg tatgtactta tttggagtcc tagtaaaaag tatcatttgg
    45061 tttttccaat ggtatttgta ttccatggct tcattgaaga cctatcagta tattagggta
    45121 aaattatttg aaaagctgca tacactaggt atgcgttatt ttgatcagac accggcagga
    45181 tcaaccgttt ctcgagtgac gaatgacaca gaaacgctat ttgaattttg gtacgtcttt
    45241 ttgatggtat tgactgggat ctttgcagtc gtttcttcat tcattgccat gtttcaaatc
    45301 aatggagaaa ttgccttgtg gactttggtg ttcttgccga ttttaggaat tgtcatctgg
    45361 tattaccaga aatttagttc tcgtatttac cgaaatatgc gggaaaaatt aagtcagctg
    45421 aatacaaaat tgaatgaatc gatttccggc atgcgtatta tccagcagtt tcgccaagaa
    45481 gctcgtttag ctaaagaatt tgaacaagtg aacaatgagt atttagacac gcgctatgcg
    45541 atgatcaaaa cgaattcgat tctgttaagt ccgatcatca attttctata tgcattggcg
    45601 attgcgttgg cgttgacttt atttgggatc gatgcgttgc attctcccgt agaagttgga
    45661 ctgatctatg catttacgac ttatgtccag ggatttttta atccaatgtc tcaaatgatg
    45721 gactttttga gcatcttcac agatgggatg gttgctggta gtcgtatctt gaagattatg
    45781 gatacggaag aatatgcacc acaacaaaac cctggagcag atcaaatgat tacttcaggt
    45841 aagattgagt ttcgcaatgt aagcttttct tatgatggag agcacaatgt attaaacaat
    45901 atctcttttg ttgctaatcc gggagaaacc gttgcattag tgggacacac cggaagtggg
    45961 aaaagctcga tcatcaatgt gttgatgcgg ttttacgaat tttatgaagg tcagatattg
    46021 attgatgatc atgacattcg agaatatcca atggaagagt tacgtaagaa aatggggctg
    46081 gtcttgcaag atgctttctt gttttatggg gatatcgcag gaaatattcg gatgatgaat
    46141 ccagctatca cagacgaaca gatacgccat gcggctgagt ttgttcaagc aaacaaattc
    46201 atcgatgaat taccaaaagg atatcactca aaagtgatcg aacatggtgc cagctattct
    46261 agtggacaac gacagctgat cacttttgcg cgaacaatcg tgactgatcc taaaattcta
    46321 gtattggatg aagcaacagc aaatatcgat actgaaacag aaggattgat ccaagaagga
    46381 ttggcgaaaa tgcgacaagg acggacaacg attgcgattg cccatcggct gtcaacgatt
    46441 cgagatgcag aattgatttt agttttagac aaaggtcata tagtagaacg cgggaatcat
    46501 gaaacacttc tagcgcaaaa tggtttgtat gcagatatgt acaaactgca aagtagtggt
    46561 atataaaaga tgttgtgaca gtagcatttt gacctaagca ctagagtgaa aataaaacat
    46621 agcttcccat atttttcatc tgtgagagtt agtgtcgtag ttaccagatt taaaaaagac
    46681 gacgtcagct agtcagaagt gcctaatagc ccctaagaaa gcgttgacaa aatcgtttgc
    46741 tttcgataat ataaagaaaa cgatacaact tggatagtga ttgcctgatg caagctaaac
    46801 ctgatgagtc tcccatggtt tcatggacgg ctttttgggt ttttcttttt gttttggata
    46861 cagccctata tatcatggaa aggagcaaaa catgctgatt gagaaagtac tgaataacaa
    46921 cgtcgtaata acaagggatg aaagagatcg ggaaatgatt gtgatgggaa aaggattggc
    46981 attcaaaaag aaggtgggtg acccgattct tgactcatgc atcgacaaaa aatttcagtt
    47041 gacaaatgac ggactttcac aacagttcca agaattggca caagcgattc ctcttgagta
    47101 cttagaaatt tcttgtgaaa tcattgaata tacaaaagag gctctgcaag tccatttaaa
    47161 tgattctgtg tatatttcat tgacggatca cttgtataca gctatcgaac gtcaaaaaat
    47221 ggggatcttt gtgccaaatg tattgctgta tgatatcaaa caactgtttc ctaaagagta
    47281 tgccattggg aaaaaaacag tgaagaaaat ctcggataaa taccacatca agttatcaga
    47341 agacgaagcc ggatttatcg cattgcattt agtcaatgca caaggcattc aaagccagca
    47401 agacaatacc tacctgttta ccacaacaat acaggatatt ttaaatatcg tccgctatta
    47461 ctataagatt acatttgatg aagattcagt ccactttttt cgattcgtca cacacctgcg
    47521 tttttttctg acacgtgtcc tagatggagc gaaatcagaa gatggagaag tttctgagga
    47581 attgttccaa gttattcaaa aaaaatataa ggatacgttt ggttgcgttg agaaaatagc
    47641 agacttttta accggggctt tcgactacca gatgtccacg gatgaaaaaa tgtatttaac
    47701 gatccatact gcgcgtttag tgcatgagaa tcgttgtaaa taaataaaaa aggaggacaa
    47761 attaacaaga acgtatgaaa taagggtagt gacattcagt tggctaaacc ttccactaat
    47821 taattggagg gaatagaaat gggaaaatac caggaattag cagaaaacat cgtaaagaat
    47881 atcggaggaa aagaaaatat ccgtagcttg acacactgtg tgacgcgact tcgtttcaaa
    47941 ctaaaggagg aaaataaagc aaaggatgat gttttgaaaa agatggaagg gatagtcacc
    48001 atcatgaaaa gcggcgggca atatcaagtt gtaatcggga atcatgtgcc agatgtctat
    48061 gcagaagtac tgacagtagc cgggatttcc gatgaagcag aagaagaggt ttcttcaagt
    48121 agtaatctgt tcaatcgatt aatcgacata ttaagtggct gtttccagcc ttttttaggt
    48181 gctttggctg cagcgggaat ggtcaaagga ttaaatgctt tgttcttgtt tctcaaattt
    48241 tatactgaag gatcgggtac gtacatcatg ctgaatggga taggggatgc aattttttat
    48301 ttcatgccag tgatcttagg gtacacagca gcgaaaaaat ttcatctgaa tccgatggtg
    48361 gggctcgtga ttggtgcagc actttgttat ccgactgtac aaggagcagc actacaaagt
    48421 ggtttccctg atggcagtcc tgcgccttat agcttgctgg gtcttccggc ttatgaaaca
    48481 tttttgggta tcccatgggt gggcagcagt tatactagta gcgtcgtacc tgttatcttc
    48541 attatcgcat ttgccggaca agtccaaaaa attgccaaga aatggattcc tgcagtcgtc
    48601 cagacctttt tggtttcttt ttctgtgtta ttaatcgcac ttcctgctgg ctttttgatt
    48661 atcggtccga ttgtcagtat actgacagat ctattaagca cgggattcca agcattgatg
    48721 gacttttctc cagctgtgta tggtgcagtt ctagggtttc tttggcaagt actggtgatt
    48781 ttcggacttc attggagtat tatccctctt gcgattatgc agctagcgca aaatgggtgg
    48841 agtcagatgt tagtaggcgt ttatggcgcg agttttgcac agacagcagt ggtattggcg
    48901 atgtatttca agttcaagga tcaaaaaatg aaggcgcttt gcatgccagc tgtgatttca
    48961 ggaatcttcg gcgtaacaga accggctatt tatggaatca ccttaccgaa gaagaagcca
    49021 tttatttact cgatgattgg tggtgctgtt tcaggaatct atttgatggc atctggaaca
    49081 atcagctaca taatgggcgg attagggatt tttggggtgg taaactacat cacggaaaca
    49141 gacgccagtg gtatgtttca agcgtttatc ggcattgcta ttgcttcggt aatcgggttt
    49201 tcgctgactt ttttcttttg gaaggatgaa gcaggtgaaa cagatgctat acagaaaaaa
    49261 tcaggtaaag aaattgtaaa aacaccgata caaggacaaa tcgctccact aaatgcagcg
    49321 aaggatgcag cttttgcaca aggaacacta ggtcgaggaa tcttaatcta ccctgaaaaa
    49381 ggagaagtac gtgccccttt tgacggaaca gttatgaccc tgttcccgac gaaacatgca
    49441 atcggaatgg tttctgaaac agggctggaa ttgctgattc atgtcggatt ggatactgtg
    49501 cagttggaag ggaaatattt tgaaagctta gtgcagcaag gagaaagagt gagacaaggc
    49561 gatctgttgc tacgcttcga caaaaagaaa atcgaaaagg aaggatacag tttagaaaca
    49621 cctgtgatcg tcaccaatta cacggattat ttggatattt tggaaaacca aggggagacg
    49681 gtcgggccag acgatgcact tatcaccgca ctgacctgaa cggttaggtg aagaatggac
    49741 taggcttaac tattcttttt attccacttc tttattttca aaattgaaag gctctttcat
    49801 gatggctgag ctgatagggc gtttatcgaa tttttgaccg acagaaatta gatggactaa
    49861 attctgttga taattttctg caaaaacaca actatataac acgtctagaa gataacaaat
    49921 tgatgtattg atcgtaaaat taccaatttt tgaatacagt cgctcgcgtg tcgtaagtcg
    49981 caaagcggct gtactcattg cagatagcgt tgaatcaccg atactggtca aagctaaaat
    50041 tggaacatca ttttgtttca atatttctgc ggtacgaagg atcacattgt tttcacccgt
    50101 ataagaaatc agaatcccgc acatatcgct cgtacaattg tacgcttcat agaatgattc
    50161 accaaaagtg gtgacaattg tgacatccat tttgatgcgc ttcattttca gcatgaaatc
    50221 ttgagaaatc aaagtattcg agttactggc gaagatcacg attttttttg cctggagcag
    50281 taaatattta gctttttgca gttggtcatg atgaatgaga gaaagtgtat catgaatcgt
    50341 catctgttct aaagaagcca ttttatttgc gattgtcata ataccgtctg tggtggaaaa
    50401 aggaagattc gcatctacgt cttgaaaatt cccttcaaga taggctgttt cagctaaaaa
    50461 agcattacga aaactgaccc agccatcaaa acccattttt tttgctacac ggatgagtgt
    50521 agacgggtgg acataacatc gctcagctat cgcttggatg gtcatttcgc caagtgctgg
    50581 agaatcgctt aagagaaact ggatcacttc attttctgaa ggagaaaagg agatttcttt
    50641 gattttttca cgtaataaca tgtagatacc ttcttcttat ttttttacgt aaattataac
    50701 ttttttgaaa atgttttgta aacggattta tactatataa cttaaaatag gctttttttg
    50761 acaagatatt tacaaaaatc cactagaaaa cagtaacttt tgtaaatgtt actggaaaga
    50821 aacggatttc tattgtttgt tttgtttaca aaaaagataa tgaaagtgta aaaaagtaaa
    50881 ggagtgagaa catggcaaaa ggaatcaaaa tcgctacgat tggtggaggc agcagttaca
    50941 cccctgagtt gatggaagga tttatcaaaa gatatgagga attaccgata cgagaaatct
    51001 ggctcgtaga tgtagaagaa ggaaaagaaa agcttgagat cgttagtcag atgtctcagc
    51061 gtatgtggga tgcttctcca tatgaagtca agatctatgc aactctggat cgggaagaag
    51121 cattgaaaga tgcggatttt gttacgactc agtttcgtgt cggtcaatta gatgcacgaa
    51181 tcaaagacga gcggatccct agttattatg ggatgattgg gcaagaaaca aatggtgctg
    51241 gcgggatatt caaagctttt cgtaccgttc cagtcgtttt ggcaatcgtt gaggacatga
    51301 agcgtttatg tccaaatgct tggctgatca atttcgcgaa cccaagtggg atggtgacag
    51361 aagcagttat cagatatggc aaatgggata aagtgattgg attatgcaat gtgccagtga
    51421 tggcgatgat gacagaacca gcaatgcttg gcaagaaaaa agaagagctg atctacaagt
    51481 ttgccggtct aaatcatttc cattggcaca aagtagcaga taataaagga aatgaccgca
    51541 cggcagaatt gattgatcgt ttatacgatg aagataatgg attaccgaaa aatatctttg
    51601 atatcccgtt tttcaaagaa caattaaaac aaatgaacat gatcccttgt ggctaccacc
    51661 gctattacta tcgtgaagaa gaaatgctgg aacatgcttt agaagaatat caaacgattg
    51721 gtacaagagc gcagcaagtg aaagaaacag aagcagagct atttgaatta tacaaagatc
    51781 cagaattaga ccataaacct gaacaattgc aaaaacgagg tggcgcttat tattcagacg
    51841 ctgcctgtga aacgattgct tcaatctatg gaaataaaga aacacagatc gttgtatcta
    51901 caaagaatga tggagctgtt cctgacctgt cggcagattg tgttgtagaa gtcactgcct
    51961 atgttggcgc acaaggagcg agaaatgtag cgtttggttc tcttcctgct gctgaaagag
    52021 gctggttgca agtaatgaag aatatggaat tgctgacgat cgaagcagct gtgactggtg
    52081 attatgggac agctttacag gcgtttacga tcaatccact tatacgatca ggaaagacag
    52141 caaaacggat catggatgag ttgtttattg cacaccagca gtatttaccg caattcaagg
    52201 aaacaatcag ccgattaaaa gaagaaggaa tcgaagttca agatgaactg gcaagagaat
    52261 tatcaggtaa tacacatata atggaggaag tataatgggg ttcagaaaag attttttatg
    52321 gggcggtgct acagcagcca atcaatgtga gggcgcttat gatgaaggtg gacgcggact
    52381 agcaaacgta gatgttgtgc caatcggaaa agaccgtttt cctgttatca ccggaaagaa
    52441 aaaaatgttt gaatttgatg aggatcattt ttatccagca aaaattgcaa tcgatatgta
    52501 tcatcgttat aaagaagata ttgctttgtt tgcagaaatg gggttcaaga cttatcgaat
    52561 gtctatcgcc tggagtcgta tttttccaat gggggatgag aaagagccga atgaagctgg
    52621 cttgaaattt tatgaggatg tctttaaaga atgccaaaag cacggaattg agccacttgt
    52681 gacgattacg cattttgatt gtccaatgca tttgatcaaa gaatatggtg cgtggcgttc
    52741 cagagaactc gttggttttt atgaaaatct gtgtcgagtc atcttcaatc gctataaagg
    52801 acttgtcaaa tattggctga cattcaatga gatcaatatg atccttcatg caccatttat
    52861 gggcgcaggg ctgtattttg aagaaggaga aaatgaagaa caaatcaaat atcaagcggc
    52921 acatcatgag ttggttgcaa gtgccatcgc aacgaagatt gctcatgaag tagatccgga
    52981 gaacaaagta ggctgtatgc tggcagcagg agcatattat ccatacactt gcaatcctga
    53041 agatgtttgg gcttctagaa aatcagatcg agaaaattat ttcttcattg atgtccagtc
    53101 acgaggagaa tatcccgctt atgcattgaa agaaatggag cgaaatggca ttcagatcga
    53161 aatggaacca ggggatgccg cattgctgaa agaacatact gttgatttta tctctttttc
    53221 ttattattct tcacgagttt cgactaccga caacgaactc ttggaacaga ctgcaggaaa
    53281 tatctttgct tctgtcaaaa atccatatct gcaagcaagt gaatgggggt ggcaaattga
    53341 tccattaggc ttgagaataa cgatgaatga tatttatgat cgttatcaaa aaccattatt
    53401 tattgtagaa aacggcttag gtgcagtcga tacgccagat gaaaatggtt atgtggaaga
    53461 tgattaccga atcgattacc tggcagcgca tatccaggcg atgaaggatg cagtagaact
    53521 agacggagtc gatctattag gctatacgac ttggggatgt atcgatttag tatcagctgg
    53581 taccggtgag atgaagaaaa ggtacggatt catttatgtc gatcgtgata accaaggaaa
    53641 tggcacatta gcccgttcaa agaaaaaatc attcaactgg tataaaaaag taattgattc
    53701 aaatggagaa aatctttcga acaattgatc aatgatttat aaaagtctat tgtttttcag
    53761 cggatttttc gagtataata aagctattcg agaaacgcaa gcagaacaat agactttttt
    53821 tcgcattggc tgtaaagtat gcttacttga ttaagtaaag gagaatctac atatgtatga
    53881 tgtaatcgtt attggcgcag gtcctgctgg gatgactgct gctttgtatg cttcacgttc
    53941 aaacttatcc gtattgatga tcgaacaagg tgcccctggc ggccaaatga acaatacggc
    54001 agaaatcgaa aattatcctg gattcgattc gatcatgggc cccgatctag cttataagat
    54061 gtatgaaagt gtctcaagat ttgggacaga aaatgcttat ggaatcgttc aagatatcaa
    54121 ggatcacggc agccataaag aagtcatctg tgaagataaa agttacgaag gaaaaacagt
    54181 cattatcgca acaggctgta tccaccgtaa attaggcgta cctggcgagg aagaatttgc
    54241 tggacgaggc gtttcttact gtgcagtctg tgatggtgcg tttttccgta acaaacgtct
    54301 agtagtcatc gggggtgggg actcagcagt agaagaagcc atctatttga cacaatttgc
    54361 ttctgaagta gtgatcgtcc accgtagaga tgaattacgt gcacaaaaga tcatccaaga
    54421 ccgtgcattt gcaaatgaaa aaatttcctt tatgtgggat acagtcgttg acgaaatcgt
    54481 tggaaacgaa atggtagtga caggtgtgaa agcacgtaat gtcaaaaccg gcaatgaatt
    54541 tgatttagca gcagacggag tattcatcta tgttggactg gatccattaa ctgcaccttt
    54601 tagagaagca ggtttgacga acgaagctgg ctggattcca acagacaacg aaatgaaaac
    54661 gaatatgcca ggcgtttttg ccatcggaga tgttcgtgaa aaagatttgc gacaaatcac
    54721 tacagctgtt ggtgacggcg gtattgctgg acaacaagtg tataaatact tggagtcttt
    54781 agaagaaaca acagcataag tttaaaaaga gtgaaagaac ggtttcaatt gttcttttac
    54841 tctttttttt cgcgtgaaat ccactgaatc cgatttatgt gaatacttgc aatcatgctt
    54901 gataaaagaa tcctttcttg atttaagcgt tttttggtcc tcatactttc atatctaata
    54961 agtgaatgct atacttatta agaaccatat ttcagaaaga ggtgttattt tcatgtcttg
    55021 ggaacaagtg tatgaacaat gggtacatga agaaaattta gaagaaaact taaaaaaaca
    55081 attaaatgat ctgggtgaag atcctgaaaa acttgaagat gctttttatg caccgttgga
    55141 attcggtact gcaggcatgc ggggaatctt aggacctggg atcaatcgaa tgaacatcta
    55201 tacggtaaga caagcaacag aaggactagc acgtttcatg gatacacaag gtgaagaaac
    55261 aaaacgccga ggtgtcgcta tcgcttatga ctcacgccat cagtcaccag aatttgcaat
    55321 ggaagcagcc aaaacactgg cacatcacaa tatcccgtct tatgtattcg aaagtctgcg
    55381 tccaacacca gagctttctt ttgcagttcg tcatttgaag acgtttgcgg gaatcatggt
    55441 aaccgcatct cacaacccag cggcttacaa tggatataaa gtctacggag aagatggcgg
    55501 acaaatgcct cctgcagacg cagatgcatt gacgaaatat gtccgtgaag tcagcaatcc
    55561 gctaaaagtc gaagtattat ctgacgaaga agctaaacat agcgggttga tcacgatcat
    55621 cggagaagaa gtggacgctg cttatctaga agaaatcaaa gcagtgacga ttgatcgtga
    55681 attggttgaa acaatgggga aagatttgaa acttgtgtac acgccacttc atggaacagg
    55741 gaaaatgttg ggcgaacgtg cgttgaaaca agctggattc gaacaattcg tactagttcc
    55801 cgaacaagct gtggcagatc cagatttcac tacggtcaaa tcgccaaatc cagaagaaca
    55861 ttcagctttt gaatatgcta tacgacttgg agaaaaagag ggagctgact tgctgattgc
    55921 aacagatcct gatgcagacc gtttaggcgc agcggttcgt ttgccagatg gttcttatga
    55981 agtattgact gggaaccaaa tcggagcatt gtttgctcaa tatattttgg aagcacatca
    56041 atcaagaggc actttaccag aaaacgcagc ggtattgaaa tcaatcgttt ccagcgaatt
    56101 gcctacagca attgcggaac actacggtgc tactatgttc aatgtgttga cagggtttaa
    56161 attcattgct gaaaaaatcc aacaatttga agaagaccat tcacatactt ttatgtttgg
    56221 attcgaagaa agttatggtt atttagttaa accttttgtt cgcgataaag acgcgatcca
    56281 agcattgctt ttattagcag aagtagcagc ttactataaa aaacaaggca aaacgttgta
    56341 tgacggcttg caaacgattt ttgaaaccta tggctatttc gcagaaaaaa cgatttctgt
    56401 gacaatgagc ggacaagaag gttctgcgaa aatctctgct ttgatggaaa aattccgtaa
    56461 agaagcaccg acagaatttg ccggagcaaa agttattcaa acagaagact ttaaagaatt
    56521 gacgagaaca gaccgtgaag gaaacgtaga aaaactaaca acaccgccat ccgacgtatt
    56581 gaagtataca ttggaagaaa atggctggat cgctatccgc ccttcaggaa ctgagccgaa
    56641 aatcaagttt tatattggtg taaaaggaag ctctacagaa gacgcagccg aaaaagtagc
    56701 ctcttatgaa gcgattatca aaaagatgac agaagaataa aaaacttgag actgatggaa
    56761 aaagtggtaa actttagaag tcagtctttt ttcaagttgg aggtgaatgg attgccagac
    56821 acgcaaaaat caaaagtaga gaaagtcagt caattattca aaatgttgag tgaccccact
    56881 cgtcttaaaa ttctgctata tctgaaagac ggggaacaaa atgtgacagc aatcacccaa
    56941 gcagtggaaa tggagcagtc tgctgtatcg catcaactac gtttattaag agaaaatcat
    57001 gtcgtcaagt ctcatcgcga gggaaaagcg attttgtata gtcttgatga ttctcatgta
    57061 ctggatattt tgaaccagac actcaaacat gtggaacatc aataacgata ggtgcaaata
    57121 gataaacact ggagtgtgac aacgaaattt cttcgttgtc acactccagt gttttttaag
    57181 aaaaagacaa aaatgattaa tcgctttttt ctgttgtttc agttccataa taactatgat
    57241 cttctaggtc taaagcattc aaaataagcg aagccgtttc ttcaatagat aaagatgcca
    57301 cattgatcac tacacatcct agtttttcat aaagatcatt cgcaaaatca agttcagctc
    57361 taattttttc gatatcggaa taagcagtat cagggtttaa tccgtaagag cgcatccgtt
    57421 ctttacggat attatttaaa atatctgggt tattcgttag tcccacgatt tttttaggat
    57481 cgatctccca aagctgtttg ggaatatgtg cttgtgggat caaaggtaaa ttggcaactt
    57541 ttaaattttt gttagctaaa aacaagctca aaggcgtttt ggaagttcgg gatacgccta
    57601 gcaaaacgac atctgcttct aaaaaaccac gaggatcttt cccatcatcg tattttacag
    57661 caaattccat tgctttgatc cgtttgaaat agttctcatt caataaatgg agggcaccag
    57721 gttgccgaat tggcttgata ccagttaaac gttcaatttc tgatatcggt ggcgtcatca
    57781 catcaaaact aaataattga tgttcttcac aaaaagaacg tgttatctcg atcagttctt
    57841 gattgattaa tgtatgcagg acaagtgctt tttcttctaa tgcatcttgc aatgcctgcc
    57901 ttaatgtttt ttcatctgtc acgaacgttc tgcggaatag gttgaactca acggtaggat
    57961 actgagccat agtagcttgc gctagttttg tcgcagtttc tccagcagag tcggagatga
    58021 caaaaaaagt aacgatttct gtagaatcgg aagacatgga taaaacctca cttgcatttt
    58081 ttttatgttt attataccat actctagaat gcgtacttcg taatcatttt gatttggagg
    58141 aataagtcat gaaaaaacag acattgatcg aacaatcatt agaaacattg aaaaataacg
    58201 gttttaaata tactaaaaaa agagaagcat tgttaactta tttagtgaag cgtaaccgct
    58261 acgtatctgc taaagaagtt tttgactata tgaatcagga attcaaaggg gtaagttatg
    58321 atacgattta ccggaatctc catgattttg cagagatcga tttactggaa gaaaccgatt
    58381 taaatggaga aatgaagttt cgttttcatt gctgtcaggg gaaaatcggc catcaccatc
    58441 attttatctg tacagtgtgc ggaacaacga aagaaatcca tatgtgtccg atgaattatt
    58501 tcgaagaaca gctaggtgga tgcacgatcg aagggcatag attcgagatt ttcggaagat
    58561 gtgaaaattg tcaataagga tttaaataaa ataacatttg ataattttaa aaaaaagcaa
    58621 gatttccttg acggtcaaaa cagcattaga tataatattt acaggacagt cttgtttttt
    58681 gagatatatt tcaataacaa ttacggttac tttttaagct cggagggagg gaattaacat
    58741 gtcaaaaaca gtcgttcgca aaaacgaatc acttgacgat gctcttcgtc gcttcaaacg
    58801 ttccgtgtca aaagcgggta ctttacaaga atctcgtaaa cgtgaattct acgaaaaacc
    58861 aagtgtaaga cgcaagaaaa aatctgaagc agctagaaaa cgcaaaaaat tctagttctg
    58921 tgatgaattg gagttggtag tgtgtcacta ctaagtagat taaacgatga catgaaagca
    58981 gcgatgaaag cgaaagataa ggaatcttta caagtcatcc gaatgatcaa gtcatctata
    59041 caaaacgagc agattaaaga aggtcacgac ttgacagaag aagaagaact aacggtgttg
    59101 tctcgtgaaa tgaaacagcg acgtgattct ttgcatgagt ttgaagaagc aggacgtgac
    59161 gatttagctg aaaaagtaaa aagtgaaatt gtaatagtcg aaaaatatat gccggaacaa
    59221 ctttccgacg aagaaattcg acaacttgtt caagaagcaa tcactcaaac tggtgcttca
    59281 tcaatgaaag aatttggcaa agttatgggt gcaattatgc ctaaagtcaa aggaaaagca
    59341 gatggaaacc aagtgaatgc gattgtgaaa gaactattac aatcttaatt ttatcattta
    59401 aactgcggac agtgattatc cgcagttttt tgtgttcgta aaaaaagaac taaaaaacag
    59461 ctagaagaaa gaatcttatt ctttcttcta gctgtttttt tcctgtttaa tatctcttat
    59521 gttaaattgt gtttgatttg gttattcttc tggtaactca cttgcttctt gtttatatcc
    59581 tgatacgcga tatacataat aaaagagcaa gctgccagcg taaccaagca acgttgggac
    59641 gacccagcca agacctaatg cagcaaaagg aacataatga tgataaaatc ctagtaagct
    59701 tgctacgaca gtttgctgac tcactaatgc aggcgaattt gccaacatat ccaatacggc
    59761 tggaacggca gaaaagaaca tcgttacttg atagacaaat ggactctttt ggaagaattt
    59821 tgctgttaag gaaagtaaga ttaacgcaag tgacaatgga tacaaaagca tcaatactgg
    59881 taaagaccat tggatgatat tatccaatcc ggcattcgca acgacaaaag agacaaaagt
    59941 cgttaaccgc agccatgtca tataactgac tttagggaac agtttatgga aatcttgtgc
    60001 aaaagaaaca acgagtccca tagcagtagt gaagacacct aatgtgacca ttacccctaa
    60061 gaagctagca ccgaagttac ctaaataaaa attagtgatc tgagaaagtg cagttccgcc
    60121 attttctgat aaagacatct tattcaaact catcgcaccg agaaggacca gaccaaaata
    60181 aatcatgact tctaacgcaa cgctcaggct accagctttt gctgttaatt ctgtgacttt
    60241 tttatcttta aaaccaagat cacgaactgc atggacaaaa gtgacactta aagcaagtaa
    60301 agctactgca tcaaccgtgt tgtatccttc taaaacgcca tttgtcaaag cgttcgtctg
    60361 ataagaatct gcagcagatt ggtttagatt ccccatgggt tggaataaag aaacgacaaa
    60421 aatgatagct aataatgcaa gaaacaagga gtttaaatac tttccgacat atttgaccaa
    60481 acgtgttgga tgtacagtaa ggaaataagc aagtaaaaag aaaagagcag agaataaaaa
    60541 catacctaat gaatcatatt tttcaggcaa aaagggttta gcagccattt caaaagcagt
    60601 tgctgctgtc cgcggtgtac caaagaatgg tccgatcgtt aaatgaacaa ggatcaagaa
    60661 caaggcagca taccattttc cgacaggttt agctaagtca tacagaccat cactttttgt
    60721 cactactaca gctaagatag ctaataatgg gaaaagagcg cctgagatgg caaatcctac
    60781 accagcgctg atccagtttg atccagccat ttgacctaag tgtacaggaa agatcagatt
    60841 acctgacccg aagaacatcc cgaagataag tgaactgacc atcaataatt gcttccatga
    60901 ataagttttt gtttcttcca taaatttttc ctccaataat tatcattttg agtaacaaaa
    60961 taaacgttgc agaaactaga aataccacta atatcagatt ccatgaaaac caccacctta
    61021 aaatataaaa aaagcccttt tccacttggg aaaagggctc tagattctag aacggtacca
    61081 ccttttttcg cttaaaaaag cttcttcatt cacggacgct tttcgataaa gttatccgct
    61141 agcctgataa tggaggcagc cacaatgatc tacgttttcg acattgactc ggaaatgatg
    61201 ttcgtctatt cgatttattg tcatttctca cttacatgac tcactgggaa taaatcactg
    61261 aatagcctac tgttttcctc gacgctttgc tgtatattta tttgttgacg ttataataca
    61321 cctgtttttt ttgaaatgca agaatatttc aaatattttg ttttcttttt ttgaaacaag
    61381 aaaaataccc agagaatact tgctaagtta gacggaatac ttgtcctcta tcttatgcat
    61441 agcttacatg atcagctttt tttattcaaa cgagaccttt agagaatgga agcggctagt
    61501 tttttaacgt ttcttggtac ttatggttaa gcaactcttt tagaaccttt tcttatttgc
    61561 tatatagttt cttctgagta tggtaaaata ggaaagaatg aatcgaaaaa aaggggatgt
    61621 ctatttttga cggaagagtc tagttcttta gagattagat tgacggctgc tgatgatgtc
    61681 agcatgcttt taggtgcaca cgacaagcat ataaaactga ttgaggaaac aacggaaaca
    61741 accatccata cacgtggaga aatcattcag atcattggtg agcaatccca gatttccttg
    61801 gctgcctcag tcattcggac attacaggaa ttgatcaaac gaggaatcca cgtaagtacg
    61861 cccgatgttg tgacggcatt gaaaatgggg caaaaaggta cattagatta ttttgttgag
    61921 atgtatgagg aagagatcgt caaagaccgt aatggaaaac ctatacgggt aaaaaacagc
    61981 ggccaaaaga aatatgtcga atcggtagcc aaacatgata tcgtatttgg cgtaggacca
    62041 gccggtacag gaaaaacttt tcttgcagta gtattagcaa tcgctgcctt gaaaaaaggt
    62101 gaagtgcaaa aaatcatttt gacgcggcct gctgtggaag caggtgaaaa tctaggcttt
    62161 cttcccgggg atctaaaaga aaaagtggat ccttatctgc ggcctgttta tgatgcttta
    62221 taccaaattt ttggattgga tcatacgaac cgattgatgg aacgaggcgt aatcgaaatc
    62281 gcacctttag cttacatgcg ggggcgaaca ttggatgatg cattcgttat cttggacgaa
    62341 gcacaaaaca cgacagtcgc tcagatgaaa atgttcttga cccgtctcgg ttatcaatca
    62401 aaaatgattg tcaatgggga tacaagtcag atagacttgc ctcgagggac gacaagtggt
    62461 cttgttcatg cagaacgaac attaaagcaa atcaagaaaa tcgattttgt taattttgaa
    62521 gcaagtgacg ttgttcggca ccctgtagtt gccgaaatca tcaaagctta tgaaaaggca
    62581 gatctccatc aagaataagc tttgcttagg aggataagca catgttgaat aaaacactgc
    62641 agaaactaca agaaaaactt ggaaaggcag cattgccttt cctgctgttc ttgtttttta
    62701 tcattatctg cggcgttaca tttagtagtg tcaaacaaaa ggccaatgat ttcagagaag
    62761 gccaagtagc agaagaaagt atccgtgcga acaaaacgat cgagaacacg gaagaaaccg
    62821 aacaaaaaag aaaactggca gcagaagcag tcactccaga atacacttac caaaaagatc
    62881 ttgcagatga ccagaacaat cggatcaagc aactatttga attgatcgat aagacgaatg
    62941 atgccatcaa caaatcttat gacgaaaaga ttgataaggc aaaggaagat gaaaatatcc
    63001 caaagcctac tacagaagag cggatcgccg cgctgaagaa aaattttgaa aatgtgaatg
    63061 cagaaaatgt tgtgttttat caaaaactac cgaacaattt ttattcgacg atatttgaaa
    63121 tgactgaaac tgagattcat actgtgaggg atgagagtct gaagctcatt gacgaacaga
    63181 tgagcaaaca agttcgtgaa agtgaattgg aagcttttaa acaagaagca gaagagcaaa
    63241 tccaatattt gaatgtcaca ccagcacaac aacaaatgat tcgctactta gtggatcaag
    63301 gtatcgtagt gaatgacgta ttgaatgaga aaaagacaga agaattgaaa caatccgcac
    63361 gagaagctgt acaaccagtg atgatcttcc aaggagaaat cattgttcgt gaaggtaatc
    63421 aaatcgatgc ttcagctatg aaaaaattgg aattactagg actgactaat caaacaactt
    63481 cgatttttcc gctaattgcc atggttttag ctgttttgct tcaaatcggc gtactgattt
    63541 ataattcact tcaattccaa aatgcaggag aaagaacaaa atacgtgctt ttctatgtga
    63601 cagctatgtc agtcagcata gtgctgatga aatttttcca attattccaa acggaacaag
    63661 ctacttatat cccgctgttt tatcccgctg cttttgcacc acttgtttta agctttttct
    63721 tgaatcgaag agcagggatc atggctggta ttttccaagc agtatccgca cttttcattt
    63781 tttatgattc gattggcacg aactttctaa cgattatctt gatgtcttat gttttctctg
    63841 ggctcatggc aacgattgtc agacgcaaac ggatctcaga acaaggatta tctgctgcca
    63901 tgtgggtcat tatttttcct gtgatgatgg atgtcatttt gatcgtctat caaggaatga
    63961 gctttggtga tgcaacgact tggttaatgc tcgtctgcgg gttcactggt gcactcttct
    64021 cattcttgct gacgatcggt ctacacccat atattgaatt gatggtcaat gatgacagtg
    64081 taattgtatt aaatgaactc agcaatccaa atcatccttt attgaaacag ttgctggaag
    64141 aagcgccagg tacttatcat catagtatga tggtagctaa tctaagtgct aacgctgtag
    64201 cagaaatcgg cggacgttct ttgctaactc gagtagcttg ctattatcat gatatcggca
    64261 agatcaaaca tgctagcttt ttcgttgaaa acttgccttc aggagcggaa aacccgcaca
    64321 atttcttatt gccagaagac agtaaacata ttatctttgg acatgtgaca gatggagcca
    64381 aaatattgga agattataat atgccgcaaa tggtgatcga tatttgcaaa cagcatcatg
    64441 gaaccacgct aatgcgttat ttctacatca aagcgaaaga acgcaatccg gaagtaacag
    64501 aagagcaatt ccgttatcct ggaccaaaac cgcaaagtcg tgaagcaggg atcgtcaata
    64561 ttgctgacag ttgtgaggct gcagtacggg caatggatca tccgacgagc gaaaaaatcg
    64621 aaagttttgt ccataatctt atcgaagagc gtatttccga tggtcaatta gacgatagtg
    64681 gactgacctt gaaagaaatc cgaaaagtgg aaaaatcatt aatcagcggt ttaagtagca
    64741 ccttccattc tcggatcaaa tatcctaaaa tgaaaacaga agttgagaag ataaaggaag
    64801 aacaagaaga atagaaagaa gcgatgtata atggatatta cctttatgga tgaaacaaac
    64861 caagtctcag aagagaaaat gaaagaaatc gatgacttgc tgcaatttgc agcatcttat
    64921 ttaaagctgc cagaggaaac agaaatgtct gttactttca tggacaatgc ggcaatccaa
    64981 gtaatcaatc gtgattaccg tggaaaagat gcaccgacag acgtcatcag ttttgctctg
    65041 gaagaagaag gcgaagacga aatcccagtg atttttgaag atggagagaa tccattacct
    65101 cgtgtactag gagacatcat gatctctatt gaacgtgctg ctgaacaagc agaagcttac
    65161 ggccattcat atgatcggga acttggcttt ttagcggtac atggattctt gcatatcaac
    65221 gggtatgacc atatgacacc agaagatgag aaagaaatgt ttggtttaca gaaagagatc
    65281 ttggatgcct atggactcaa aagataaaaa cgtagagaaa aacaaacatt tcctgatgtc
    65341 tgtggaattt gctgtccaag gagtcaaaac cgtttttgag gaagaacgca atatgaggaa
    65401 acatgttgcg ttcggtatcc ttgctttatt tatgggcgtg attttccagc ttgatcggat
    65461 agagtggtta tggctgcttt tagctgtttt tctcgtttgg atagtagaga tcatcaatac
    65521 tgtttttgaa aatgtagtgg acatgtttac ggattttcat tttcatccga ttgggaaaaa
    65581 aatcaaagat atggcagctg gagcagtttt agtgaccgct tgttttgctg tcatcattgg
    65641 gttgatttta tttgtcccta aaatatatca tttgttgttt aattaaaaag gagaacgtat
    65701 atgccagaac ataaatcagg gtttgtcgca atcgtcggcc gcccgaatgt aggaaaatcc
    65761 acattattga accgaatcgt gggtcaaaaa attgccatta tgagtgacaa ggcacagaca
    65821 actagaaata aaatccaagg agtatatact acaccagaag ctcagctgat ttttatcgat
    65881 acaccaggaa tccataaacc aaagcatcgt ctaggagatt ttatggtaga agcagcttac
    65941 agtgcgttga aagaagtgga tgcagtctta tttatgatca gtgctgatca aaaacgtggc
    66001 cggggagacg attttattat tgaacgtcta aaaaacgtgc attctcctgt ttatctgatt
    66061 atcaataaaa tcgataagat ccatccagac gagttgctgg gaatcatcga agattattcg
    66121 acgcagatgc cttttgcaca agtgattccg atctctgcta cagaaggaaa caatgtcgaa
    66181 cgcttaatgg atgtattagt cagtgaaatg ccagagggcc cacaatattt tccagatgat
    66241 caagtgactg atcatcctga atacttcatc gtttctgaat tgatccgtga gaaagtcttg
    66301 tttttaacac gagacgaagt gcctcattct gtcgcagtcg ttgttgattc gatgaagcga
    66361 aacgagaatg ataaaatcca tatccaggcc acgatcatcg tcgaaagaga tagccaaaaa
    66421 ggaatcatta tcggcaaagg cggaaaaatg ctgaagcaag taggaacgaa agcaagaaag
    66481 gatatcgaaa atcttttagg agacaaagta tttctagaac tttgggtcaa agtccaaaaa
    66541 gactggcgag acaaaaaagt ctatctgcaa gacttcggct accgaaaaga cgagtactga
    66601 tattctggac ttcttatagg ttaggtatag aaataaactg gataaaaatc cgtacgttga
    66661 gaaaaacagc ggaagatcga aacataaata atctggatcg gcagaatctg cttttccaga
    66721 tttatttttt aggagggaga atatgagcca gcttgcagaa tcgaaaggct tgattttatc
    66781 tagccgtaat tacaaagaaa aagataaatt agtcaaaatc tttacggaat cttctggcaa
    66841 aatgatgttt tatatcaaag gaatccatcg gcaaaatcag ccattagctc cggctttgct
    66901 cccctttacc gaagcagtct atatcggtaa ttttcgaagt gaaggtttgt cgtttttaag
    66961 cagtgtcaaa gacgtccatg cgtttcggaa catccaagaa gatatctttt tgagcggtta
    67021 tggtacgtat ttgctaaatc tagtagatgc agcaatcgaa gatcatcaat atgacccgca
    67081 tttattccaa tttacgcaac aagctctgca gcggatggac caaggagatg atgcagaaat
    67141 catcacgaat atctttgaag tgcaaatact gcaacgcttc ggaatcgcgc caatttggac
    67201 gcactgtgtc gtatgcgggg aaacaaaagg aaaatttgac tattcttcca aatatggcgg
    67261 tgtgatatgc gagaaacact ggccaatgga cgaacaccgt tatcatgcag atcctcgcgc
    67321 tgtttatttc gttcgaatgt tttcggctat ttcttatgat aagatcagtg gaatccactt
    67381 gaaagaagaa acgaagcagg caatccgtga cctcattgac cagttgtatg atgaatatgt
    67441 cggtattcat ctaaaaagca aaaagttcat tgatcaaatg aagtcttggg cacacgtatt
    67501 aaagacgcca gagaaaaata tgcctgaaaa agagatacct gaaaaagaag aataaatgaa
    67561 agatacaaca aaaaaatcaa aactatttga caaatacagg gacttccgtc tattattaac
    67621 cgtagattaa atagatcgtt cactgagagg atctattata caaaccagaa aactgcaaaa
    67681 tgaatacgta cattgaccaa gatcagtaaa aaacacgtgg tttagcgagt tcgggagagt
    67741 ggaagccgga cccaaacgat ttttgaagag gcacttgcga gtacgataaa tgaagctgcc
    67801 gaatctttat tcggaagtag ggtggaaccg cgaaattatt cgtccctatg tctgtaatca
    67861 gacataggga ctttttgtcg ttttctttcc tgtattctta ttgacagcaa cgcttaaaaa
    67921 ttgaaagggg caaaacagat gagtaaaaaa ttgaccgtcc aagatatgat tttaacatta
    67981 caaaaatttt ggtcatcaaa cggctgcatg ctgatgcaag cttatgatac agaaaaagga
    68041 gcaggtacga tgagcccata tacattctta cgggcaatcg gaccggaacc atggaatgct
    68101 gcttatgtag agccatcccg ccgaccagct gacgggcgtt atggagaaaa cccaaaccgt
    68161 ttgtatcagc atcatcaatt tcaagtcgta atgaaacctt cacctgaaaa tatccaagag
    68221 ctttatttag aaagcttgcg tcttttagga attgatccat tagaacacga tattcgcttt
    68281 gttgaagaca actgggagaa cccatcgatg ggttgtgccg gtgtgggctg ggaagtatgg
    68341 cttgatggga tggagatcac acaattcaca tacttccagc aagtcggagg actaccttgt
    68401 aaaccagtta cttctgagat cacttatgga ctagaacgtc ttgcttctta tatccaagaa
    68461 gttgaaagtg tttatgatct ggaatgggct gatggcgtga aatatggtga gatcttcaaa
    68521 caaccagaat atgaacattc taaatattct tttgaagtaa gcgaccaaga cctgctacta
    68581 agcaattttg atcgttttga aaaagaagct aaacgctgta tcgatgaaaa tcttgttcat
    68641 ccagcgtatg attatatttt gaaatgtagc catacattca atttattaga tgctcgcggt
    68701 gcagtatccg taacagagcg tgcaggttat ctttcccgta tccgcaacat ggctcgtgct
    68761 gtagccaaaa tctttgtggc agaacgcgaa aaattaggat tccctttatt gaataaaaac
    68821 acagcaaatc cagaaaacgt gaaggaggct gaataagatg gcaaaagact tattacttga
    68881 aatcgggctg gaagaaatac ctgctcatgt agtcacacca agcatgaaac aattagaaga
    68941 aaaaacagca aaatttttag atgaaaacca attgacttat gatacgatcg aaacgttttc
    69001 tacaccgcgc cgcttagcaa tcaaagtaac aaacattcca gaacgtcaag cagacagcga
    69061 agaagaagtc aaaggaccag ccaaaaaaat tgctttggac gcagatggaa actggacgaa
    69121 agcagctgaa ggatttgtcc gcggacaagg tctgacgaca gatgctatca cttttagaga
    69181 attaaaaggc gtggaatatg tctatgtaac gaaatacact cacggcaaag aagcaaaaga
    69241 agtattgaca ggtttagcag atgtcattaa aagcctcact ttcccagtaa cgatgcactg
    69301 ggcagaatac gattttgaat atattcgccc tattcactgg atcgtggcat tgttagatga
    69361 cgaaataatc ccgtttgaga tcttggatgt caaaacagac agagcttcaa gaggtcatcg
    69421 tttcttaggc gaagatgtga catttacgca tgcaaaacaa tacgaagaaa aattgaatga
    69481 acaatttgtt attgcttcac cgcaaaaaag aaaagaaatg atcatcacac aagcaaacga
    69541 attagcagaa aaaaatcact ggatcattga tctagatgaa gatttactag aagaagtcaa
    69601 caatttagtc gaatatccaa ctgtcttttc tggcgacttc gaagaaaaat atctatctgt
    69661 tcctgaagaa gtactagtca cttctatgaa agaacatcaa cgttatttcg aagtacggaa
    69721 cgatcaaggt atgttgcttc ctcattttat ttctgctcgt aatggcgatc gggtaaaatt
    69781 ggaaaatgtg gtacgaggca atcaaaaagt attgactgct cgtttagaag atgcggaatt
    69841 cttttataat gaagacaaga aagcttcaat cgaccaatac gttgaaaaat taaaaactgt
    69901 tactttccat gaaaaaatcg gtagcatcta tgagaaaatg caacgggtac aagtcatcgc
    69961 tcgcatcata ggcgaacaag taggactatc tgaggaagaa ttgatggatc tgcaacgcgc
    70021 tgctgaaatc tataaatttg atctagtaac caacatggta ggagaattcc ctgaactaca
    70081 agggatcatg ggcgaaaaat atgctctgct taaaggcgag aaaccagccg tagcaacagc
    70141 gatccgtgaa cattacatgc ctatatccag tgaaggagat ttacctgaga ctacagtagg
    70201 ttctgtttta gcgattgctg ataaattaga tagtatcttt tctttctttg cagttgggat
    70261 gatcccaagt ggctcaaacg atccatatgc tttgcgccgt caagcatatg gtgtcgttcg
    70321 aatcatcgaa tcgaaaaaat gggcctttcc tttgtctgtt ctgcaagaaa cgattagtga
    70381 agttatcagt aaagatacgg atcgttttgg cattggcttg tcagcgggac aacaacaggt
    70441 gatcgacttt atcaaaggcc gtctgcgcca attattgaca acgaagaata tccgtcatga
    70501 tgtcatcgaa gctgttttga atgcagaaca aaaagatctg acaaaagtat ttgcagcagc
    70561 acaattgttc aagcagcatc ttgcagatga agacttcaaa ccatcgatgg aagctttgac
    70621 acgtgtcgtg aacttagcga aaaaagcgga gcttgaaaaa caatcagaag tagaccctga
    70681 actgttcgaa aacgaagcgg agaaagaact gcacaaagca gtagaggcaa tgaaaacaag
    70741 ctttgctgac caaacgatca acgaaaatta tgatcagctt gtaagccttc gcccactgat
    70801 cgaaaattat tttgatcaga cgatggtcat ggcagaagaa ccagcagtac gtaagaaccg
    70861 attaacgcaa ttaagtcaaa ttgctgccat ggctttgtca ctagcaagtt tagatcaaat
    70921 catcacaaaa taatttctaa tatgtaaata aacc
//
LOCUS       DAZAOD010000007        65152 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000007 DAZAOD010000000
VERSION     DAZAOD010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.007"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1421)
                     /locus_tag="ACHDPO_000497"
     CDS             complement(<1..1421)
                     /locus_tag="ACHDPO_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFN3368158.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAG"
     gene            1673..2854
                     /locus_tag="ACHDPO_000498"
     CDS             1673..2854
                     /locus_tag="ACHDPO_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFN3368159.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(2914..4542)
                     /gene="treC"
                     /locus_tag="ACHDPO_000499"
     CDS             complement(2914..4542)
                     /gene="treC"
                     /locus_tag="ACHDPO_000499"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFN3368160.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(4993..7704)
                     /locus_tag="ACHDPO_000500"
     CDS             complement(4993..7704)
                     /locus_tag="ACHDPO_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFN3368161.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7714..8415)
                     /locus_tag="ACHDPO_000501"
     CDS             complement(7714..8415)
                     /locus_tag="ACHDPO_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368162.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8601..9200
                     /locus_tag="ACHDPO_000502"
     CDS             8601..9200
                     /locus_tag="ACHDPO_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFN3368163.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9281..10294
                     /locus_tag="ACHDPO_000503"
     CDS             9281..10294
                     /locus_tag="ACHDPO_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFN3368164.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10402..11319
                     /gene="rbsK"
                     /locus_tag="ACHDPO_000504"
     CDS             10402..11319
                     /gene="rbsK"
                     /locus_tag="ACHDPO_000504"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFN3368165.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11347..11742
                     /gene="rbsD"
                     /locus_tag="ACHDPO_000505"
     CDS             11347..11742
                     /gene="rbsD"
                     /locus_tag="ACHDPO_000505"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFN3368166.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11742..13115
                     /locus_tag="ACHDPO_000506"
     CDS             11742..13115
                     /locus_tag="ACHDPO_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFN3368167.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13472..15616
                     /locus_tag="ACHDPO_000507"
     CDS             13472..15616
                     /locus_tag="ACHDPO_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFN3368168.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(15668..16708)
                     /locus_tag="ACHDPO_000508"
     CDS             complement(15668..16708)
                     /locus_tag="ACHDPO_000508"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFN3368169.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(16985..18787)
                     /locus_tag="ACHDPO_000509"
     CDS             complement(16985..18787)
                     /locus_tag="ACHDPO_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368170.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18801..19553)
                     /locus_tag="ACHDPO_000510"
     CDS             complement(18801..19553)
                     /locus_tag="ACHDPO_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368171.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19562..19924)
                     /locus_tag="ACHDPO_000511"
     CDS             complement(19562..19924)
                     /locus_tag="ACHDPO_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFN3368172.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20100..20972)
                     /locus_tag="ACHDPO_000512"
     CDS             complement(20100..20972)
                     /locus_tag="ACHDPO_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFN3368173.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21023..21511)
                     /locus_tag="ACHDPO_000513"
     CDS             complement(21023..21511)
                     /locus_tag="ACHDPO_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFN3368174.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(21649..22440)
                     /locus_tag="ACHDPO_000514"
     CDS             complement(21649..22440)
                     /locus_tag="ACHDPO_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFN3368175.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(22495..23103)
                     /locus_tag="ACHDPO_000515"
     CDS             complement(22495..23103)
                     /locus_tag="ACHDPO_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFN3368176.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23096..23413)
                     /locus_tag="ACHDPO_000516"
     CDS             complement(23096..23413)
                     /locus_tag="ACHDPO_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFN3368177.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23569..24297)
                     /locus_tag="ACHDPO_000517"
     CDS             complement(23569..24297)
                     /locus_tag="ACHDPO_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFN3368178.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24456..25337
                     /locus_tag="ACHDPO_000518"
     CDS             24456..25337
                     /locus_tag="ACHDPO_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFN3368179.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25574..26617)
                     /locus_tag="ACHDPO_000519"
     CDS             complement(25574..26617)
                     /locus_tag="ACHDPO_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3368180.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26620..27288)
                     /locus_tag="ACHDPO_000520"
     CDS             complement(26620..27288)
                     /locus_tag="ACHDPO_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFN3368181.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27430..29766
                     /locus_tag="ACHDPO_000521"
     CDS             27430..29766
                     /locus_tag="ACHDPO_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFN3368182.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29881..30192)
                     /locus_tag="ACHDPO_000522"
     CDS             complement(29881..30192)
                     /locus_tag="ACHDPO_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368183.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30373..31848
                     /locus_tag="ACHDPO_000523"
     CDS             30373..31848
                     /locus_tag="ACHDPO_000523"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFN3368184.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31895..32479
                     /locus_tag="ACHDPO_000524"
     CDS             31895..32479
                     /locus_tag="ACHDPO_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFN3368185.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            32481..32864
                     /locus_tag="ACHDPO_000525"
     CDS             32481..32864
                     /locus_tag="ACHDPO_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFN3368186.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(33181..33465)
                     /locus_tag="ACHDPO_000526"
     CDS             complement(33181..33465)
                     /locus_tag="ACHDPO_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFN3368187.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33817..34527)
                     /locus_tag="ACHDPO_000527"
     CDS             complement(33817..34527)
                     /locus_tag="ACHDPO_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFN3368188.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34524..35996)
                     /locus_tag="ACHDPO_000528"
     CDS             complement(34524..35996)
                     /locus_tag="ACHDPO_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFN3368189.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36134..36607
                     /locus_tag="ACHDPO_000529"
     CDS             36134..36607
                     /locus_tag="ACHDPO_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFN3368190.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36760..37311)
                     /locus_tag="ACHDPO_000530"
     CDS             complement(36760..37311)
                     /locus_tag="ACHDPO_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFN3368191.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37416..37946
                     /locus_tag="ACHDPO_000531"
     CDS             37416..37946
                     /locus_tag="ACHDPO_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFN3368192.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38429..38872)
                     /locus_tag="ACHDPO_000532"
     CDS             complement(38429..38872)
                     /locus_tag="ACHDPO_000532"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368193.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38888..40048)
                     /locus_tag="ACHDPO_000533"
     CDS             complement(38888..40048)
                     /locus_tag="ACHDPO_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFN3368194.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40555..42255
                     /locus_tag="ACHDPO_000534"
     CDS             40555..42255
                     /locus_tag="ACHDPO_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368195.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42357..43190)
                     /locus_tag="ACHDPO_000535"
     CDS             complement(42357..43190)
                     /locus_tag="ACHDPO_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFN3368196.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43494..45659)
                     /locus_tag="ACHDPO_000536"
     CDS             complement(43494..45659)
                     /locus_tag="ACHDPO_000536"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFN3368197.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45919..48213
                     /locus_tag="ACHDPO_000537"
     CDS             45919..48213
                     /locus_tag="ACHDPO_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFN3368198.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48206..48871
                     /gene="pgmB"
                     /locus_tag="ACHDPO_000538"
     CDS             48206..48871
                     /gene="pgmB"
                     /locus_tag="ACHDPO_000538"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFN3368199.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            48864..49871
                     /locus_tag="ACHDPO_000539"
     CDS             48864..49871
                     /locus_tag="ACHDPO_000539"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFN3368200.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49893..50912
                     /locus_tag="ACHDPO_000540"
     CDS             49893..50912
                     /locus_tag="ACHDPO_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3368201.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51193..52560)
                     /gene="nhaC"
                     /locus_tag="ACHDPO_000541"
     CDS             complement(51193..52560)
                     /gene="nhaC"
                     /locus_tag="ACHDPO_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFN3368202.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52669..54090)
                     /gene="tyrP"
                     /locus_tag="ACHDPO_000542"
     CDS             complement(52669..54090)
                     /gene="tyrP"
                     /locus_tag="ACHDPO_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFN3368203.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54333..56210)
                     /gene="tdc"
                     /locus_tag="ACHDPO_000543"
     CDS             complement(54333..56210)
                     /gene="tdc"
                     /locus_tag="ACHDPO_000543"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFN3368204.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56501..57757)
                     /gene="tyrS"
                     /locus_tag="ACHDPO_000544"
     CDS             complement(56501..57757)
                     /gene="tyrS"
                     /locus_tag="ACHDPO_000544"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFN3368205.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(57869..58074)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            58337..59638
                     /locus_tag="ACHDPO_000545"
     CDS             58337..59638
                     /locus_tag="ACHDPO_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFN3368206.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59707..60306)
                     /locus_tag="ACHDPO_000546"
     CDS             complement(59707..60306)
                     /locus_tag="ACHDPO_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3368207.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            60560..61441
                     /locus_tag="ACHDPO_000547"
     CDS             60560..61441
                     /locus_tag="ACHDPO_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFN3368208.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            61454..63064
                     /locus_tag="ACHDPO_000548"
     CDS             61454..63064
                     /locus_tag="ACHDPO_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368209.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(63141..63800)
                     /locus_tag="ACHDPO_000549"
     CDS             complement(63141..63800)
                     /locus_tag="ACHDPO_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFN3368210.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(64083..64748)
                     /locus_tag="ACHDPO_000550"
     CDS             complement(64083..64748)
                     /locus_tag="ACHDPO_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFN3368211.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT        19547 a        13263 c        11751 g        20591 t
ORIGIN      
        1 tttcctgcat ataaatgaaa atgttcggag tcagccggtg caatcgtgtg atcactgaat
       61 tgaatatatc taaaagcgcc actttcctta tcttctgctt cgaatagata ccttacgcca
      121 cggtttcctg cctcgtaggt caagatttct ttccctacat aacgataatt tgaacgtttc
      181 gttgttccat tcttaaacgt aaatgccatc tctttctcac tgatcttgat tgaagcaata
      241 tctgtttgat agcccttcgt ataatattct ttatattctt gtgctgtctt atcctgattc
      301 aatttttctt tatattcaaa aacaggatca aaagtcccat cttctacata cgtatctact
      361 gtttgccaag ttcctgccca atctgaaaga gagcgatctt gtacatcctc gtcttcaaaa
      421 taaccgttgt agacgctctt ttcttttttg ggggtcaaag tatcttctag cgggttttct
      481 gtctctgtcg tttttttcaa cgcttcgagg tttgcttcca tgatagaaag atagttttct
      541 ccattttcta tttgttcatt cgtcaatcct tccaaaggat tcaatacttc taaagataca
      601 cctgcttcgt ttgctaacgt tctggcaata ctatctttgg cgttttcttc aaaataaata
      661 tagttgattc catgttcttt aacaaagtgt ttcagttcag caattctcgc cgcagacggt
      721 tcttcactag aagaaagacc agcaatcgat acttgattca atccatattc taacgctaga
      781 tagttgaatg cagcatgttg cgtgacaaaa gatctttgtt ttgcttgctt aaaggtttct
      841 tgataaagct gatggagtgc ttgaagtttc tcggtatagg ctgctgcatt ttttgtccat
      901 acttcctgtt tttctgggta agcttcaatc agctgatcac gtatgtttgc tacctgcttg
      961 attgctaaac ttggagctag ccatacatgt gggtctagct catgtgtatg gccttcttcc
     1021 ccgtgttcat ggtcatgatc atgtccttct tcacttcccg gaagtaaaag cataccttct
     1081 gtcgctttta tcgtatggac attgccttct tgtaatgttt tttggattgc ggggacccat
     1141 gtttccatgt tttcatcatt ataaacaaag atatctgtat cttggatctt tgccatgtct
     1201 ttagcagaag gttcataatc gtgggaatca gtccctgctg gaatcaataa ctctacttct
     1261 ccttcatccc cgacgattgc ttttgtaaaa tcatacatgg gataaaaggt cgtcatcacg
     1321 ctcaattttt ctttactgtc ctcggctttc ccacttgccc cgcaagcagt taacatacct
     1381 gctaaaacca gcatggccaa tatacctatc aatcgtttca tttatgacac tcctcttctc
     1441 atcttctttc atttgaatgt tccgattcgc ttttcgcaaa ccgtaatagt tacgttttag
     1501 caacaggatt taatttatca tatggttaaa agaactgtca agcgttttct tattttaatt
     1561 gatgagaaag tttatatgaa tgattgacga tatttttgca atcaacctct atcattttcc
     1621 ttttataccc gcttttgtct ataatgaagt tatagataaa ggaggaaaaa gagtgaaaaa
     1681 agaaacagat acaacgaatc gtttgatccg ctttttagga ggaaaaacct cttactatgt
     1741 tttaggaata gttatcttac ttgcgctgat catttatttt ttccatcaga tctcgtttat
     1801 attcaagcct gtcggaatca ttatcgctac tatcttgccc ccattattgt ttgcactgat
     1861 cttgtattat cttttggaac cagtcatcaa acgtttgagc aagcaccttt cgaggaactt
     1921 gtcagtcatt atcgtttatg tgattatttt atttttattg gggcttggaa gcatatggct
     1981 tattcctttt cttgaagaac aggcaaagac attgatcagt agtttgccag atttgtttca
     2041 agattttcaa gagagtctcc gacaattttt ggagaaaaca ccttttgccg attcatttaa
     2101 tcaatttttc gcttctattg acgacgtgac gtctgatata gctggattta ttggaaatta
     2161 ttgggaaagt ggcgcacaac ggatcagcaa cattttttca actgttacag ctatttttat
     2221 tactttattt actggtccaa ttgtcgcttt tttccttttg agagatcctc aaaaatttta
     2281 tcagtcagtt ttagcgattg tcccaccagc atttcgtaca gattttaaaa atttgacaaa
     2341 gattgctaat caacaattgg gttcatttct aaaggggcaa atcattgctt catttatcct
     2401 tggagcagtc tactgggttt gtttcttact gatcggatta gaatttgcta gtgttttagc
     2461 tatttctgct gggttgttat gtatcattcc atatattggg ccgtttatcg ccttctttcc
     2521 aggtttgatc attgcattcc aagactctac ttttatggct gtcaaatttg tcattgtctg
     2581 gtttgccgta caacttctcc acggtgactt ggtgattcct cgagtaatgg gtgatcgttt
     2641 acagatccat ccgattacga tcttaatcgt tttacttgtc atgggtgatc taatgggaat
     2701 tgtgggcgtt atttttggta ttcctatcta tacgttagtc aaattactcg ttacttttat
     2761 tttccgtaaa ttcaaacaac gctacaataa attttatggc gataaaggag agtatgaaaa
     2821 ctcttcattt tctgaagaag attattttaa ataaaacaca aaacgtcgat cttacgagaa
     2881 tagctcgtag gaacgacgtt ttgtgttttt gttttaattt ttcagcaaag caattgcctg
     2941 gtatggtttt agctccagac tttgatgaag aacagtatcg gaataattat cgataagaat
     3001 attggcttct gtgaatcctt ctgggatggc gatccttgta tctttatcat agaaatttgt
     3061 taatacaagc agctgctgtc cttcaaattg gcgaagaaag ccataaactt ccggatgatt
     3121 tgcttcataa gcatgataat ctccttgtgc aacgattgga tatgtttttc tcagccgaat
     3181 caatttcttg taataggaca aaatagaatc ttcagaagat agttcttttt ctacattaat
     3241 ctcttctagc ttgcctccaa cttttaacca aggtttccct gtagtaaatc ctgcttgttc
     3301 tgtgtctgac cattgcatgg gtgttcgaga gttatcgcga gattttgctt tgatccgacg
     3361 aaacgcttct ttttctgtga atccttgttc aaggagtaac ttataagcat tcaaactttc
     3421 tacgtcaata tagtcggaaa tcgatgaata gtctgggtcg atcatgccga tttcttctcc
     3481 catataaata tagggcgtcc cacggttcaa atggatcatg gttgctagca tctctgctcc
     3541 ttgttttcga tactgatcga tagctacaaa tcgattgagc gcacgtggct gatcatgatt
     3601 attaaaaaat agagcattcc agccgttacc ctcactcatc ttttctcccc atgtatgaaa
     3661 tagtcgcttt aattctgcaa aatcaaatgg aggagtagac catttattcc cattttcata
     3721 atcgactttc aaatgatgga aattaaagac cattgataat tcttctctac taggttctgt
     3781 atacaagata caattttcga tcgtcgtaga gctcatttca ccgactgtga tgatagtgga
     3841 atccgtccca aacgttgctt ggttcaattc ttttagatac gtatgggtga ttggtttgtc
     3901 cgtatattca ggtttgccat cattttcttt attatttttc aattgttcgt ctttaccgat
     3961 aacattgata acatcgaaac ggaatccttt tacccctttt tccatccaaa aacgaacaac
     4021 tttgaatagt tcctctctta ctgcttggtt ccgccagttc aagtcagctt gtgtccgatc
     4081 atataagtgc aaataatatt tccccgtatc tccaaatggc gaccaagcac ttccaccaaa
     4141 ttttgatacc caatccgttg gctcttctct taaaatgaag aagtcctgat aatgctggtc
     4201 ccctgctagt gcttttttga accattcatg ttctgtcgaa acgtgattca gcaccatatc
     4261 gagcatgatt tctatccggt atttctttgc ttcggctatt agctgttcga attcctccat
     4321 cgtaccaaag ataggatcga tggctgtgta atcagagata tcataaccgt tgtctttttg
     4381 agggcttgga taaatagggt ttagccaaat catgtcgatg cctagatcat tcagatacgg
     4441 gagtttttct ttgattcctt ttaaatctcc aattccatca ccattactgt ctttgtaaga
     4501 tttgggatag atttggtaaa tgactttgtc tttaaatgtc atggatattt acctccattc
     4561 aactgattta ttacctacca caacttatat atacaagtta tcatttatta ttataactga
     4621 accgaaagcg tttgtaaaat ttatctttat acattctaag aggtctgttg cccaataaaa
     4681 aacaagagat cagacatgta tttgtctatc ctcttgttta aaatagcaaa atattcttgt
     4741 ttcttctata aatggtgttc aaaagctttt atctacggca atcagtcttc tcaaatgtaa
     4801 aacatgagga gctaatttta tttgagtatt ctttttgctc gatgcaggac ggctttttta
     4861 caacctctga ttcatggtgt tcaatcagct gtccttcggt attagctcaa aaaacggcaa
     4921 aatatgaaaa actattttgc cgtttgtttc tctaatactc aggtcaaacc gctgatttca
     4981 caacctctgt ttttattcat tcgatttcaa cgcatcaatc atatcgatat gctttaattt
     5041 gaaatgggta acaatcatca caataaccgt aaatacgata gttaatcctg ctgataagac
     5101 ataagcccac catgtgatca ctaatggaaa gatgacattc tccatagacg cttgttgcaa
     5161 gatgaagtca gtcaatatat atcctacacc aaatcctccg atgattccta aaagagtaaa
     5221 gatgatattt tctcgaacaa tgtacatcgt gacttcttta tcaaaaaatc caaggacttt
     5281 tattgtagat aattcgcgta cacgctcgga aatattgata ttagttagat tatacaagac
     5341 gataaaagcc agcagtcctg ataatacgac aaagattaag acaaccgagt ctaagttcgc
     5401 cattgattct tcttgcgttt cgatttgttt ggacatgaaa gacgtatttg tcacagcgtc
     5461 tgtggcaagc agtttctcgg aaagcatttc ttcttctttt gttgtcatct tatctgtacg
     5521 cagcaaaaat gcattatcca tcatcgattg atcagtaact gaagcataat attcagggga
     5581 catataaata aagctaccta gatagttttt cacgatttct tttacttcga ctttccattc
     5641 tttttgatct tcatcataaa gcgaaatatg atctcctgta gataagtcaa atagttctgc
     5701 tactttttgc gtaatagcga ttcctgtttt aggcaaggag cgtgggttct cttcaagatc
     5761 agttaaatgg ataaaacgat ccaaatcagc tgttttactt ggtacgatca ctgtcagact
     5821 ttgcgaagca tgtccttttt ttctcaattc tacggtttga gtatgaatag ctaggatctc
     5881 atttactttt tcttgcttct gcagcatatc cgctgctttt tgacgactat cttccgtgga
     5941 tgaatccaat gtaacgattg cttgatagtc aatgatcggt ccaaattgtt tggctgaaac
     6001 agaacttaga gaatctttca atcccacgcc tgcaaccatc agcccggcac atccagcaat
     6061 tccgataatc gccataagca ttcttgactt atatcggaag agatttcggt aactgatttt
     6121 ttgattaaag ctaaggcgtg accacagcgg agtgatgtat tcaagaaaaa tgcgtttccc
     6181 tggcttcggt gctttcggtt gaagcaatgc agcaggccgt tctcttaaat ctttgaataa
     6241 aacgatcatt gcagcgccaa atgcggcaat gaagaatgcg gcagctgctt gtaaaatcgg
     6301 cggccagtca taaaaaataa gcgcactccc aatatcatac cgctcgttag acagctcaaa
     6361 aatgatcctt ggcaaaagat tcgttcctaa tatcgttcct aaaacaatac ctatccctga
     6421 ggctagactt gcatagattg catatttttt tgcgatttca actttcgtat aacctaacgc
     6481 ctttaatgtc ccgatttccc tgcggttttc ttctaccata cgtgtcattg tcgtaaaggt
     6541 gatcaatgcg gcaataaaga aaaagaaaac aggaaaaaca ttggcaatcg cagcgatacg
     6601 atcagacaga tcaccaaatt cttgaaaacc gacattttct gaacgttcat tgtataggta
     6661 tgatggttta gttaaatttt caattttttc tgcatttcga ttcaattctt cctctgcaga
     6721 ggccagttca cgttctttct caactaattg cctttcttgt tcagcaagtt gagcttcttg
     6781 ttgagataat gtttgaacag cgattgttcg ttgcgcttca ggaagctgct ggatagttgc
     6841 tgactgttgc gctaactgtt ttttagcatc ttctaaccgt gttcttgctt gcgttgtttg
     6901 tgctttgcca tccgctattt tttgctgtgc cggttctaat tcttcgttgg ccgatttttt
     6961 cagctcttct aagcgttctt cgggtcgatc ttgtaaatac ttttctgcct tttcttgatt
     7021 ttgctccatt ttatctttgt aagctttgct gtacgtattc aaattcttta cgtttgtaaa
     7081 atcaagatat aagacagaat aaatatctgt tttaaaaacg gattcaggta aatagacaaa
     7141 ataatcgacg ctaccatttc cgacgttcgc gtatcctctc tccaaattgt tgatgaacaa
     7201 tggagaacgg acaaagcccg tgatggtata ctctttttct ttcaattcat ctgaatcaat
     7261 ctgataaata tcaccgattt tatacccttc atcttccgct ttttcatcca atacaagctg
     7321 gtttggtttt tccgggagtt ttccatcagt taattgtagc ttgttctgct tgttattttt
     7381 gttataagaa aatatttgaa tcacttcgtt tttgccagta ttggaataat agatctgttt
     7441 tcctgtttct acttttgcat ctgggatctt ttctgcttga gcaatatctt tttgtgtcaa
     7501 gccaccagta gaaacgattt gcaaatcaga aagtcctgct gtaccaacat agtgatccat
     7561 cgttttttgc atgacaggtc cagcagtttt gacacctaca aataaaagtg ttcctagcat
     7621 gacaataagg atgattgcaa tgaatcgtcc tttagattgc cgaatttcgc gaaaacctgc
     7681 tttaagatat gttcttgttt tcataaaatc cccctaccat acaatctcat caatggatga
     7741 aggatgatca tttaattcaa cagaccttac tttagcatca ttaatgtgaa tgactctatc
     7801 agcgatgggc gctaaagcag aattatgtgt aatgatcaaa acggtattgc cgtgttgtct
     7861 gctagcgttt tgcaataatt tcaatacttg cttgcccgtt tcaaaatcca gcgcgcctgt
     7921 cggttcatca cataaaagaa gtttgggatt tttagctagt gcacgagcaa ttgaaaccct
     7981 ctgctgttcg cctcctgata attgggacgg aaagttattc aatcgatgag ctaggcccac
     8041 ttgcctcaat acctctacag gatcaagcgc atcaggagaa acttccgttg ccaattccac
     8101 attttctttt gctgttagat taggaacgag attgtagaat tggaaaacga accctacatc
     8161 tgttcgtcgg taagcagtaa gctgtttatc tgaaaattgc gcaatatctg tgtcatcaat
     8221 aatgatctga ccttcatcag gtgtatccat cccacctaaa atattaagaa tcgttgactt
     8281 tcctgctcca cttggaccaa gtataatcac taattcgcct ttttcaattg aaaaagaaat
     8341 atcgtcattt gctgtaatgg tcgtttctcc cattttgtat cgtttgtatt cattttttac
     8401 ttcgacatac ttcactctga ttcctccatt ttcacgatat ttctcgctat atctatgcat
     8461 cgaatgcgtt ttctcacact tatttatttt accactgaat ttctctagac taaagaaagg
     8521 aatcctttaa tttagttgac aaataaacga tttatgattt acttacataa aaaacattgt
     8581 tatttgaaag aaggaacatc atgaatgatt taaaggaaaa tatgattttt gatttatcaa
     8641 aaactgcttt tgtcgcgatc gacatgcaaa aagagatcgt aaataacggt acactctctc
     8701 cacacactgc agcatctatt ctgacaaaca atgatttgtt agtaagaaca ttgaaacgta
     8761 ccgctgcctt gaaagtttta gtgaacgtag acatctccac tttcccttat ttgagtcaac
     8821 aaactgatat gggtggaatg actgcttctg tacctccaga attcactgat ttacttttga
     8881 aggattcttt gaaagataca gataatatgt tgactatcac aaaatacaat ccaagtgctt
     8941 tttttggtac ttctcttgat cttcaacttc gccggcgtgg aatcgaaact atcattttaa
     9001 gcggtgtagc gacaacaaac ggtgtatatg ctactgcatt agatgccttt caacacgggt
     9061 accatatcgt gcttgctgaa gatgcttgca gtgatcgtga caaagaatcc catcaattgt
     9121 tcataaaaaa gatatttccg aaaactgcac gagtacgctc aacgaaacaa ataatcgaag
     9181 ctatccaaca aagcaaataa gtactggcac acgtgatttt catttacttc tttttgattt
     9241 catgggaaaa taaccacagg atttagatag gagtatgaac atggtgaaaa aaaagatcac
     9301 aatcaaagaa gtcgctaaac tttccggcgt ttcaatcaca actgtctcct tgatattaaa
     9361 tggaaatacg gagaaattca gtccgaaaac tgttcagaaa gttttagctg ccaaagaaga
     9421 attaggctat cagcctgact attttgctag acaaatgatt accaaggaaa cgaaaacaat
     9481 tggtgtactc gttcctgata tcacgaatcc attcttcagt acactgatgc gaggaattga
     9541 ggatatcttg tataagcaga atttcgtcac gatattatgt aatgctgatt ctgatcatca
     9601 aaaagaaatc gaatatctag ccgagctcac acgtcgaggt gtggatggat tcattatcgc
     9661 gacttctgct gtctctacag atgcaatcaa cgaaaatttg aaaaaacaag gccggccctt
     9721 cattgttttg gatcagaaaa aatctgaagg atttagtgat gccgtacgaa cagacgattt
     9781 tcgcggtggt tacctagcgg gcatgcactt gcttagtcta ggacatcaaa cgatcgccct
     9841 tgtctatcct gaaaatccac cggaaaatgt ccacgctcgg attgaggggt ttaaatctgc
     9901 tcttgatgtt taccaaatcc ctcacgacca actgatcctc ttacctacac agttctcaaa
     9961 acaaggtggc taccagatca cagcagaact tcttgattct gctgcaactg gtgtgtttgc
    10021 tttaaatgat gaattagctt ttggattata tcgcggatta gaggaagctg gaaaaagcat
    10081 ccctgaagac tacagcatta ttggctatga taatatagat atgtgcgagt atatcaagcc
    10141 gaaactgaca acgatcgcac aaccaatctt cgaattggga caaacatctg ccaagttatt
    10201 gttagatcgg atccaattcc cagaaaaaga atgggaagaa aaaagattac ctgtacgatt
    10261 agaaaaaaga ttttcaactg cacccttgaa atagctttca aggtgtgcta tatttttatc
    10321 gaactattaa aacgttttac taaaacgttt taaaaaataa ttttcccatc aaaataaatg
    10381 agatagttgg aggtttgtaa aatgaacacg gttacagtaa ttggaagtat taatatggac
    10441 actacccttc gtttaaccaa catgcccaag ccaggcgaaa cgatgcatgc gcatgagatt
    10501 tttcacgctg gcggaggtaa aggtgccaac caagcagtgg cagccaaacg ttcaggcgca
    10561 cggacatctt ttattggagg cgttggggct gacagcgaag gacaacagtt attagatcta
    10621 ctgacaaaag aaaacatcga tacatctggg atagctgaaa tccaaggcgc cacaaccgga
    10681 caagcaatga ttatggtaga cgcagcagga gaaaatagta tcttgatcca tgcaggggca
    10741 aataatgctt tccatgaaca agaagtccta aaaaacaagc aactgattac aaacagtgac
    10801 tttattattg ctcagtttga aagtagctta gatgcgacga tcctagcttt ttctattgca
    10861 aaagacgcag gaaaaacaac gatcctgaat cctgcaccag ctcgtgaaac gattcctact
    10921 gaactacttg aaaagacaga tatcattata ccaaatgaaa cagaaacaga aatcattaca
    10981 ggaatcagag tgacagatca taacagtttg gtcgcagcag ccgaaaaact ccatgaatta
    11041 ggtattggaa cagtaatcat tacactaggc agtgccggcg ctttctatca tacagaaaaa
    11101 gaacacggta tcgtccctgc ttttaaagtg gatgccgttg acacaacagc cgcaggtgat
    11161 acatttattg gcgcattaag cagcacactt cagccagacc ttagtaactt gaaagaagcg
    11221 atcctttatg gaaatctagc ctcttctgtt gctgtgcagt cttatggtgc gcaaccttct
    11281 atcccttacc gcgaagcttt agaacaatca gcagtctaaa attaacaatg agaggaagaa
    11341 acaaacatga aaaaaggaaa agtaatcaat tcagatattt cacgagtaat cgcacaaatg
    11401 gggcactttg ataaattaag tatcggggat gcaggcatgc ctgtcccctt tggtactgaa
    11461 aaaatagatt tggctgtctc aaacggtctt ccaagttttt tatctgtttt agaaaacgtt
    11521 ttagaagaac ttgaggtaca atcgattgaa ttggcggaag aaataaagac aatgaacccg
    11581 gaaatattgg aaaaaatcaa attattgtta ccagatacac cgattagctt tatcccacat
    11641 gaagaaatga aaaaagagtt gaataactgt catgcattta ttcgtacagg cgaaatgaca
    11701 ccttacgcca atattatatt agtgagtgga gtggtcttct aatggaaacg acaatgaatc
    11761 ctgaacagat ggtactgtcc gagcagattc atatgctgat tgaacagttg ggaggaaaag
    11821 acaatattga ttctgtcctt ccatgtgcga ctcggcttcg tatcaaattg aaaaaacagc
    11881 cagtagccaa tgcagaaaaa ttaaaacagc aaatcccttc cattaagtat ttcattttac
    11941 tcgatagata tgcagaaata atcatggatc agggattggc tcctgcttac aaggaattga
    12001 cgcgtcaaat cgatcattca gctccgaaag aaaagctaaa tccgatcgaa aaactatttg
    12061 gtttgatatc ggaaatcttt acgccgatca ttccgctgtt tgccggttct ggtatattaa
    12121 aaggtctggt tgttttagcg actacgattg gctggcttag tgaaacaagc ggaacttatc
    12181 atattttgtc tgctgcgtcg aatgccgtct tttattttct gccaatcttt cttgcttttt
    12241 ctgctgccaa aacgtttaaa gtgaatggat atattgcggc tgtcattgct gcagcactga
    12301 ttgaaccgaa tctgacctct ttactttcag acagtggcaa agcagctact gattttctgg
    12361 ggattcctgt agtactgatg cagtatacgt ctactgtcat gccggcgatt ttaggtattt
    12421 tcttttattc ttttgttgaa aaattcctca aaaaatatat tcgcgaaaat atgcaattag
    12481 tatttgtacc tttactttca ttagttatca cggttccttt gacgttaatg gtattcgggc
    12541 ctgcgggtgt ttaccttggc gaaggtttag ctgccgcaat tacttggatg atggatatta
    12601 acggaccgat cagtggcgca atcatcgctg gtggttggaa tattttggta atatttggta
    12661 tccaatgggc tgtaaaccct gtcatgatca gtaatatctc tgcttatggg ttcgaccgaa
    12721 tcgttccgtt gacaggagca gccaattttg gaatggctgg tgcagcttta ggtgtatttc
    12781 tgcgaagtaa acgttcaaaa acccgttcga tctccggttc tgcttttgct tcgattttac
    12841 ttgcgggagt gaccgaacca actgtttacg gaattgcgat cccattgaaa aaaccatttg
    12901 ttgctgcttg cattggtgca gctgctggtg gagctgtaat gggatttgcc caagtgaaag
    12961 cgatcgcttt tgtatttggt agtctgacca cattgcctgc attcatttcc ggtacttttt
    13021 tctggtactt agcaggactg gctgttagtc tagtcgtagc aatgatcact actctcgtta
    13081 gcgggtttga tgaagaccta atgtcttatg aatagttaat gaaaaagact gaagtatgag
    13141 atgtttatca catatttcag tctttttctt tttaggatca ttatttttat aaatttttgt
    13201 gatactttcc aaactttggt ataatttaca tatgcataac catttttatc cccacttgtt
    13261 tatccccaaa caaaggtggt ctatgcaata aaatgaacgt caaagaaaaa cgaatgaatg
    13321 ctcgttgctt atttacaaat tgttttattt agaatacaca gacagattta tgaaaagaaa
    13381 aagcttttcg acacgattat ctgttccaaa aaatgtctaa tgaatgctga ataagacaga
    13441 aaatcaatga aaggaaaagg actagtttat tatgaaaaat aaaaaaacga tacgtttgct
    13501 agctgctact tggctgattg ctccgtctgt tttgtcgacc aataccgtat ttgccgtaga
    13561 taatcaaata gctgatcaaa cagtcacaac agatacgact acatccagct cagctactag
    13621 tgaaacaacg gattctttta cagaagaccc aactggaaca actaactcaa caacaggatc
    13681 gaccgagcca actgaaattg atccggctga tccatcagaa aatgaaaagc cagccgagac
    13741 atattccctt acaattgctc cttctttgat tggtaagatc caactgactg cttcgacagc
    13801 ggattcccct gaacagcaac ctttggatat tacggaaagt ggaacggtag aaggtttatt
    13861 agcggaaacg aaggtaactt acactattac gccagctgaa ggtgaacaaa ttgcttcagt
    13921 cgctgttaat ggtgccaaag aagtaaatta tgatgcaaag acctttacag taggtacgaa
    13981 caatttatct attactgcag aatttaaagc tggaccggat acttcaacag agaaaccaac
    14041 tgatcctagt gaagaagtcc ctagtacacc agatccggaa acgccaaaca aaccagatgt
    14101 gggtaataac aacaataata atggttcaaa taattcaaac aataataaca ataattcgaa
    14161 cagcgggaat tcttcgaatc aaacaaaccc atctggatcg aataacaatg gaaatactca
    14221 gagagaacca aaccatccaa acaatggttc atcgaatggc ggaacgaaca atgcttcatc
    14281 tcgtccaaat acagcaaatc aaagcggtat agagaatcca tcttctgctt cttctgattt
    14341 tgttgtaaaa tcaccaattg atgctgtatt gcctacaaat acaacgaatg tccaacaagc
    14401 aatcgttcga gaagcattca agcatcttgg aaaaccatat gtatggggag caaaaggtcc
    14461 aaatactttt gactgttctg gtttgactta ttacgtatat atgaaagcaa ccggtcatta
    14521 tatcggtggc tggacaggcg aacagcaata tgcaggtacg cagattccag taagtcaggc
    14581 ccaacctggc gacctcgtct tctggggacc ttcttccggt gttactcacc atgtaggtat
    14641 ctatattggg aacggacaat ttatccatgc gcctcaacca ggagataaag ttcgagtaac
    14701 ttctatttca gatttcacgc ctgattttgc tgtccgagta aacttagcag gtttacctgc
    14761 tgcttcaggt tcgctgacag gcggctcatc tattttagat ggattagatg gctcgttcca
    14821 tttcagtcaa aaccaaacaa ctgatcagtt cttgaaaaag attgcagatg atgcacagga
    14881 aatcgggcaa aaagaaggaa tctacgcatc agtcatgatg gctcaagcta tccttgaaag
    14941 tggatctgga aacagcttat tatcaagcga accaaatcat aacctttttg gtatcaaagg
    15001 atcatataaa ggaagcagcg tgaccttcaa tacacttgaa caagatagtt ccggacaaag
    15061 ctaccaaatc cgcgcacaat tccgtaaata tccttcttac aaggaaagtt tggaagacta
    15121 tgccgacttg atcaaaaatg gactgactgg caatcctgat ttctacaaac caacttggaa
    15181 gtcggaaaca aaagactaca aagaagcaac caaatatttg gaaggacgtt atgctacaga
    15241 tcgccaatat tcacaaaaat tgaacgcgat catcgaagcg tacgacctga caaaatatga
    15301 tgaaccgaaa aaagaagcag caacaactga agaagcaaac gctgaaatcc tcaatatgtc
    15361 taagcgattc gatgtgccaa tcaaatggac aacagatggc gtgccaatca caggattaga
    15421 attttcaacg ataaaacgcg tcaacaacgc ttcttccatc ttccgtgtcg cttcaatctg
    15481 ggatttgtgg aacaatttta cggcaagaca gataccagaa acaactactc gtacagttaa
    15541 agctgcaact gttcctgtac taaccttgtt aaggttagac aaatcattct ggcttgatct
    15601 gcctttaaag aaatagaata aattaaaaag gggatgtgac actgtcacac tcccttttta
    15661 atttattcta tttctttata tttattttgt attccgttac aaactcgcgt acttggttag
    15721 gttccagagt gacatctcca aaactttcaa gtcgctccgc tcctggcagt tcttgagtct
    15781 caaatgtgat accgccatga tttactaatt tattcccgcg catttccggt ccatcttctc
    15841 caaaatttgc tgtaaaaatc acgattcctg aagcatctgt ttttacttgg atcgatactt
    15901 tttcatctgg gcttgtcaat tccgcagcat ttagtaaacc agattgtttt ttcaacaaaa
    15961 atggatgatc gatgccgccc actatcattg attggcgaaa atcactggca aagacctcac
    16021 ctaatttttt aggacgttgg aagtcaaatg ctgtgccact tactgaaact acttctcctg
    16081 taggcgttgt atctttattg agcgtagcaa ataatcggct attcaaccaa agtatatgtt
    16141 cgtcgattga ctgtgctgga tcaccggtta aattgaaata gacatgattt gtaggattga
    16201 atactgtttt gcggtcactg atcccttgga ccgtcactcg ccatgtatca tcgttcgtca
    16261 gcgtataccg tacttctaca tctaaagttc caggaaatcc gttttccata tctgggctag
    16321 tctgatagaa aatgaccgat gcttcgtttt caccattgat gactgtataa tgccactgct
    16381 tggcttcaaa gctaggtgca ccaccatgta aacaatgacc agtgtccggg tctgttttta
    16441 cttcgaacgt ttcatcatct aatttgaatg tgccattcgt aatccgtcca gccatacgtc
    16501 cgattgaagc accgatataa gggtcttttt ctagatattc ttttgcttca tcaaaaccta
    16561 agatcaactc tcgtttttca ttatcgatta ttgtttgaaa atgaacaacc cgtgccccaa
    16621 gatcactgac agacaaagat gtcccatttt gattcgtgat cgtaatcaag tgatagtttt
    16681 cgccaaaatt ttgttcattg atttccatgt tccttgcacc ctcttttctt tcatttgcac
    16741 tgattccagt atacatggaa accgttttct taacagctta ttccgtgagt aacgagaaaa
    16801 aatttactat attctaataa aagaccgtga aaaaaaggtt gtgacaaaaa tattgtcaca
    16861 acctcttttt ccgaacaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca
    16921 aacgaaaaat atgaggagct atttttgctt ggctgttctt attacttgat gcaggacagc
    16981 tttttcacaa tctctttttc aatacgattc cagtatataa ccatgtcgtc agtacatagt
    17041 agatgaaata caatacgaag aatatcgtaa acggaaccca aatatctttg tatggatttt
    17101 gcatgaatag accaaacatt tgtaatccga ataagacatg gactacacct aagattcctg
    17161 gtgctaagaa taacacgcct acttctctac ggatcgattg tttaagcaac ccgcgtcgtg
    17221 ttcctatctt ttcaagcatt tcataacgag caatgtcact cttgcttcct gacaagatct
    17281 tgaacatcaa acagctagca agcatggtca agaaagctaa acctaggaag aatcccataa
    17341 attcaaaacc agagaataga ccattataca cttcatacat ttcatatttc tggttgctgt
    17401 actctacttt ttgcaaagat ggattgttca ttttattttg agcaacaagt gtttcgattg
    17461 gtttcaggtt tgcttggaag tcttttacct gaactagctg taaagtggat tgtggcaagt
    17521 tcagttgatc aaattctgat tgactgacta ccttgatttc tttttcttgc tgttccggca
    17581 attcatagct tcgaagttcc tcttgtacag tcagttcatt cattttttta gcaggaactt
    17641 tttctttcgt gatcttcggc ggtgttccat cttcatgttt tatcatgatc aatggttgag
    17701 ccgcaaattc acttgcatta tagtaaatcg ttcccgcatc ttctttttga gtataagaag
    17761 cagaaagtgt tggtgaaagt tctttgattt tttgctgatc ttctgcccga ggattattca
    17821 tcactagatc atatccagaa ttgttttctg tcaagtctgc aatttcattt ttaaaaccta
    17881 atcctaccgt caaagcgccc agtgccaagg caaacagcat agcgaccatt gagagcattt
    17941 gtgtatattc acgaatacga aagtttaact gtgacaatgt gaaattgttc aattttttca
    18001 atgaaatctg ttctgatttc tttagtaatg ataaaaagaa aatgatcaca gaatggaaaa
    18061 tgaaataagt tcctaatacg atcgtaacta aggctacccc tataccaaag acttgatagg
    18121 tccccacgtg tttcatcata tagtaaccgc agcctagaaa agcaattccc agtactactt
    18181 caaggaaaaa caagaattta tgctgcttga ttcttgttgg tgtctgatcc gcacgaatca
    18241 atgctaaaat cggttttttg acaatcgaaa aagcattgac aacagcagct aataaaaaca
    18301 aaacagcaaa aaacaaaaca gtgatcaaca acccgtgaat actaaaaggt gtaaaatgcg
    18361 aaatattgag atctaactga tccactaata atcggtggac gatacttgtc aatcctacac
    18421 cgacagctga acccactaaa gtagctgcga tccctactaa gaatgtttca gaaaaaatca
    18481 tctgtgcgat ttttctgcct tttgctccca gcatcataaa cattgcatag tctttttgcc
    18541 gcatcgtcat caaaaaggaa tttgcatata aaatataaac gaatgtgatg atccctagta
    18601 aaacagaacc gaatcggaaa atgataactg tagccgcaac gatcgtatta cttttcaaaa
    18661 aagcttcgtt gcttgccatt gattcaaaca tgtaaaaaat agcagatgcc ataactaatc
    18721 ctgagaataa caccaagtag tctcttaaac ggctcttgat cccagtaagt gataatttcc
    18781 aaagcatagt caatctcccc ctactgttcc aagtttccaa gaatagatag tatttctcga
    18841 tagaaggaat cacggctttg atctccacgt ttcacttctt gatggatacc gccatccttg
    18901 atgaataaaa tacgttggca ataacttgca gaaaacggat catgcgtcac aagaagaatc
    18961 gatacatgat cttttgtatt caattcgtcc atcgtatcta aaagatcccg ggcacttttg
    19021 gaatccagcg cacctgtagg ctcatcccct aatagaatcg ttggttgtgt gatcaatgca
    19081 cgtgcggcgg cgacccgttg tttttgtcca ccggaaatct cagaaggata gctttccaaa
    19141 atatgagaga tggataaacg ttctgcaatt ttttggacac gttgcttgat ttcttttggt
    19201 ctgacgcctt gtaaagaaag aggaacagcg atattttctt gtgctgtcaa gctttctaat
    19261 aaattgaaat cttggaaaat aaagccaatc tcattcgcac gaaaatctgc tagttgattt
    19321 ccttttaatg tggtcacatc tttttgattg attcggatat gcccatctgt tggtttatct
    19381 aatgtggata aaatattcaa aagtgtcgac ttaccagaac cagaagcgcc catgatccca
    19441 ataaattcgc ctttttctac atcgaagctg atgccgctta atgcttgcgt ctttttctca
    19501 ttgttttttc cgtatacttt tgttacattc tgtacttcga ctattttgtt catttctttc
    19561 cctacccttt aattagtttt tccagtgctg ttttcggcac gtcttttttt tcgacttctt
    19621 catacgaagt gacaccttta tttttgttcc aggtgatttt taaatatgct cctttacgaa
    19681 gcggtcgagt caattgtccc ttgaagtcca gttctttttc cttaccctct ttcgtatagc
    19741 caggcaggat atatctatag ttgactgttt cttgtccaga gtctgatttt gaaactgttt
    19801 ttgtaccatc tgtcgtaatt tgtacatagt attcttctcc acccataact acgtaatctg
    19861 cgattttcac ccctgcaagt accacaacga tgaaaacaag tagaccgatc agaagttttt
    19921 tcactttttc cccttctctc ttactttata tactgattat agaaaaaagc gaacaattct
    19981 gccttcgaat caactatcat tcttctttca attttgtcat tttctttaaa acaactaaaa
    20041 aaagagttca agacaataat ccgtcctaaa ctccttcttc ctatcttaca aaaagtatgt
    20101 cacttacggt ctttcatgtc gcctgtattg ataacaggtt gcgttccttt gtctgtaatg
    20161 attgagacaa gtaaattatt gatcaattgg actttccgat catcggtgaa attgatttct
    20221 tgtccatctt cgatttgctc taaggccatt tgagtgattg tgacagctcc ttcaacaatg
    20281 gtttgtcgag cagacaaaat ggcttttgct tgttgacgtt ggagcatggc actagcgatt
    20341 tctgttgcat aggctaaatg gttcaagcgt gtttcgatta cttcgacacc tgctactgct
    20401 aaacgctctt gcagctcttt ttgcaactcg tcagacactg ccgtcgtgtt tcctcgaagc
    20461 gtcaaatcat tctcattgaa tgtatcatac gggtattggc tagcgatatg ccgaatggct
    20521 gtctcacttt ggatttctac aaaatcttga taatacgcta catcgaataa tgcctttgct
    20581 gtatcaacga ctttaaagac tactactgct gagatttcga tggggtttcc atccaaatca
    20641 ttgactttta aaacagaact attgaaattc cgaactttca acgaaacagt cattttttgt
    20701 gccaaaggta tcgtaaggaa aaagccattt tctcgaatcg tacctaaata ttgtccaaaa
    20761 aacaaaatta cttttgcttg attaggactg actacagttg ccgaacttaa caacaataac
    20821 gtgatcaacc aaagaaaaat acttaaaaaa agtgcccaaa ctttcgcttg ccacatacct
    20881 aaatagaaga aaaacaatcc aactaaagct aatacgacca atccgacaat ccctgcataa
    20941 ccattgatat aaaatgctct tttttctctc atgctacttc ctgcgctcct ttatccttca
    21001 ataaatatct aatgttactt ttttaatttt tttttcgaat acgcgccatt acaccttcta
    21061 gttctaactc tttgtcttca gtgatgtacc aaccgcttgc ctgtgtccct ccggctgcct
    21121 gcggtaaata atccaatttt gttcgaaccc agtgcttttc ttctgtaaaa tagtcttcta
    21181 ccaagacctc tagatccatc cctgctgaaa gaggcaaatc ttcccgaaca gatttaaaga
    21241 taaatcgttc cttcttccca tcatacttca atattcctgt atcgataatc ggtaaagaat
    21301 aataatccag ctctttcttc accgtcaata aatgtttgaa aacttcatgg tacacttgct
    21361 ctaattggcg accttctgaa ttgttcgggt aattaaccat cactttttct ttgtctggat
    21421 catagaaggt ttggcttagt tgagtgatat aagtatgtaa tctttccatt tctgttttta
    21481 acttttctct ttgaccttct tctaccttca tatactcttt caccctgttt tctttttaga
    21541 tattttcttt cttattttac tatagttatg tgcgttaagc gatgaaaaac agcaaagatt
    21601 ggaaggatct ttgctgtttt ttcttaaaat atccagttga gtacaggatc aatctgtttc
    21661 attgtcctct tgatccgtcg taatattgat cgatgtgtct ttagcagtga tctttagctt
    21721 tttctgtcct tgttctaaca aagtatttgt tattggctgg tagtcttttt caatataaga
    21781 ttcaccagac gtttggatag tatagccact gttttccatc tcatgcaaag ataaattgcc
    21841 accgtttagg atgacttttc cttctttgct gatcaaactg tcttctagat ggaagttgct
    21901 gttttcacct gtgacgatca agttatccac attggcctca tctaatcgaa gtgagcctaa
    21961 ttcatctttc gcagttattg ttcctcctgt aaattcattg aacgataccc agccatcatg
    22021 tgtcttagta ttcacttttt tgattgatac ttcgttgata tcaattgcac tattattccc
    22081 ttcgattgtc aattcagata attcatgatc tgcagggaca acaatagtga tttgtgcact
    22141 tgtgtcttct aaactaatga ttgcacctgt tgattttttg actgcattca cagtcaacac
    22201 gccatttttc tcctttattt ctggcttttc tgtcttatca taagtcgttt ttatctcaaa
    22261 atccaatccg cgtatgaccg aaactgtttg attttctgca tggatgacga ttttgtttgc
    22321 atccttgatt ttttttgtct cagtaaccat atcgatcaac cgaggaccat tatcccaagt
    22381 cagactcttt tgagcgccta atgtataagt tgcacctgct aggaggccac cagtaagcat
    22441 cagaccaata ccggtaatca aaaaatgttt caatctcaat ttatgtgtcc tccttcaaac
    22501 gcccgctgaa tgcagatctc tttttgtaat aaaacgtcgt cccatccatt taacaaagtt
    22561 catcatgaca taaaaaagcc cttttgttcc tttcagcaac agtggcgaaa taaatactgc
    22621 gcttcctgtg gcgaacagac cgacaccgat aaagaataat ccactcagaa tcgattgtcc
    22681 aaacacactg attcctgaga tgatcatgaa taggccaaca cctaagatac tgatacataa
    22741 aacatagata ctaaaaatga gcgctagtaa agcaaccaat agtcccccaa taaccaatat
    22801 aaaccccagt gctagtggaa tgaggacagg agaagcaaat aaaccgataa tgattaacca
    22861 aatcaggcga atttgtcttt ttggattttt cactaactcg ttttctgctt gttcttcttc
    22921 tgaaaagtaa ctgattttta attttaaggc aaactgcttt ggtgtaccat attcatcaat
    22981 gatctgatct aatgtttttc cagaatctaa aaaatattcc tcataatact ggatcaaatc
    23041 aaaacgatcg tcttcaggaa tttcttgaag atgatccaca acttcattca aatattcatt
    23101 catttgtgct ctcctccaat aaccggtcta aagaatctcg aaaaacaatc cattcatcaa
    23161 taatttcttc taaatgacga cttcccattg gtgtcaacga gtaatatcga cggtttctgc
    23221 cttcaaaagg ttcatcatag gtctcaagat atccttcttt tttcaatctt ctcaaaaccg
    23281 gatatagtgt agattcactg acagagagac tttcttgtac gatttttgtt aaggcatacc
    23341 catacatatc ttccttgctt aatgctgcta gcacagtacc atcaagaaga acagttggaa
    23401 tctggatgtg cattacgtca ccttctattc tcaagtgtaa tattttattt caatctatat
    23461 tatacaacat ataatatagt ttcaaaatca gtttgtcaaa tacaaaaaaa ctgactaaaa
    23521 gatttgatcc tttttagtca gcaaaaaatg gcttctcttt gatttttatt ataacagtgg
    23581 cataatccaa tttgtccaca tccagctcag tggcatgata acgatcattg caggtatcat
    23641 gtcagctact gggaacattt tcacgttgat cattctaaaa ccggtagcga ccatcaagaa
    23701 tccgccgcaa gctttaaaat ctaagatcat gtctggtgta gtcaatggat aaataaattt
    23761 tgccaataag aacaaaatat aaaaaataat gaattgggga attgctatca cagaaacgac
    23821 ataccctaaa ttacacgcaa aaatagctgc tgtgaaaaaa tcaaggacag atttagaaat
    23881 caaaatcgta ctgtctcctg tcatcccaga atctaaactt ccatagatcc ccgtaccact
    23941 tgcacaaaat agaacaatga ccgtcactaa tgtgctgata aattcatcgt gggtcatacc
    24001 aagcttttca ctagggaaga ttttagaaat aggtacttgc atcagcgcag cccccttatt
    24061 tatcccatta cctaaatgaa caatcaaacc aatcgctgtt cctatcacta aagcaaaaat
    24121 aacagccggc atatttttca tcggcgcaat ggaatagatt cccatcccca tcgaacacac
    24181 accaaaaacc atcgtcagct gtgctttaaa atgttcactt aatttatttc ctactaatcc
    24241 gccaattagt ccgccaaaca aaacggaacc tacattgatc aaaactccag ttggcatcaa
    24301 aaaactcctc tctttttcta cgaagcgaaa aaaatcagaa aaatttctgt aattattgct
    24361 ttcgctgcaa gaaagattgt aacagacaga gaagattaca ccaattcatt ttttgtgtta
    24421 aagtattctt tattggaata agtaggagga atatgatgga tatccataaa ttcgaagttt
    24481 ttcttgattt agccgaaaca atgaatttca ccaaaactgc tgatcgacaa ttcaccaccc
    24541 aaggaaatat ttctaaacag attctttcgt tagaaacaga attagacgtc aaattattcg
    24601 aacgcgccca tagaaaaatc gaattgaccg aagctggaag cttattgctc ccatatgtaa
    24661 aaaatgtcgt agaacaatac catgctatgc aagaagtgct tgaaacctat acgaaagaca
    24721 acaatctttc attaaatatc ttaacgatac cgacaatgat caattataaa ggtttttcca
    24781 aaatcaccga gtttttgaaa cgccatcctg aatttacagt ccagttgaaa gaagtggaaa
    24841 gtgtcgaatt aacttacaat gacgccaatg aacatagtga cacgatccac tttgctagaa
    24901 gtttccaggc cccaccaagt tcgattgagt ggttgcctac tgaaacagac gattttgtag
    24961 cagttctacc taaaaatcat cctttagcta gtaaaaagaa attggatcta agcgaactga
    25021 aaaaggagaa ctttttgctc cttggcccca ctacgaactt gtatcaacct gtactagatc
    25081 tgtgtcgcga agctggattt gaaccaaaaa tctcttataa aggagcaaga atcgacttga
    25141 tcatcaatat gattgcaaat gacatgggga ttgctattgt tatggaaaaa acagtcaaga
    25201 atctattaaa agaaaatact gtgattctcc ctatttctcc aacaacagag agttatcttg
    25261 catttactcg taaagtcggt gagcattctt tggcttcaga tacattttgg gagtatttaa
    25321 atcaagaaga aaactaagcc ctacattttc tgtccatcta tccacccaaa aaaagagagc
    25381 gacgcatgac tttcgctctc tttcttgcat catgtccttg tttcaatgac acctctaaca
    25441 tttctcgtag ttcaataaga aagcagcgat ttttatgcca aaagaaccgt aagaacattt
    25501 ccctaatcac aaaaaaacga ctaaaaaccc ctaaaaacct tcaatagaat ttttaggggt
    25561 tttattcttt ttcctattgt ttacttaacc gtatcattgc tgtcgttcct actccttcga
    25621 tactgctata atcaatacgt ccatcatgca gttctagaat ttttttaacc agtgaaagtc
    25681 ctagcccatt cccagaaatt tgacgacttg tatctccttg ataaaatttt tcaaacattc
    25741 gatctctggt ctcttcattc attcctacac ctgaatcggt cacttccagt acaatctctg
    25801 tggctgtctc aaatagtttg atatgaatct gtccattgat ttgattgtac tttatggcgt
    25861 tatccatgat attcagccac acttggtaca aaaactcttc attgcctgtg taatttactg
    25921 cagcaagttc gatatccaat tctagctgtt ctttctccca tttaggctga aaaaaaacga
    25981 ttacttctct gatttgttca tctaatcgat actctttctt ttccagttgg atacgctggt
    26041 tttccagttt gttcaatttt aagatgttct ctgttaattg tgaaagctgc gtgatacttt
    26101 cgataatccg atataaaaat atttggcgtt cttcgtcaga gagatttggg gcttgtaaca
    26161 attgaacata tccttggatt gttgctagtg gtgttttgaa ttcatgggat acactggaca
    26221 caaagtcatt cctcagtgtc tcgatactat tgagttcttg gaccataacg ttgaaatctt
    26281 tatacagttg ctgtacttct gctactttct gctgttcatc cattcgaatc gaaaaatctc
    26341 ccgttgctac cagactcata tttgtcccta gcgcactgat tggatgcagg atacgccgcc
    26401 caacaaaaat cgatattcct gtacccacga ccatactgaa ccccgcaaag acgaataacg
    26461 ggtataacgt tggttttcca gccgattcag caggcgagat agaatgtcga gacaataaga
    26521 aaataaaacc gagaaaacac agcagtgtca ctaagatcga aatgaagaca atactagcaa
    26581 aatagatcca taattgtgaa aatagctttt ttttcatctt taaataaccg ccttatagcc
    26641 tagtccccgt actgtgatga tttgaaaatc ttccgtcttt tcaaaacggg tccttaaacg
    26701 tttgatatgt acatcgatcg ttcgttcttc tgtattcgta tctaatcccc aaatatcatc
    26761 catcaactgt tggcgagtga agatcttgtt gggataagac agtaatttat acagaagcag
    26821 aaattctttt tgaggcagaa tcaacgaatg ctgatcttgt aacactgtat aagcatctag
    26881 ctctaatttt gtttgtccga ttatcaagct actgctgtaa ttgatctttg aacgtcgaag
    26941 caatgcttcc acacgtagga tcatctcatt gacatcgatg ggttttgtca tataatcatc
    27001 tgctcctaat ttgaacccgc gtttcttatc ctcaaaatcg gcctttgccg taatcattag
    27061 aacaggtgtg tcaaatctgg tgctacgtaa tgagtctagc aagtcatagc catccatttt
    27121 cggcatcatg atatctgtaa tgattaattc tatacgtgtc gcttctagtt ttttcagcgc
    27181 atcctctcca ttcaatgcgg tgatgactga aaagcccgct cgttccaaca cagaacggta
    27241 aagcaactgt aattgcggat catcttctac tactaaaata cgattcattg atctccctct
    27301 gttttttgaa aaatttctag attttttctt gtagttcatc ttcagttaac atttatttcg
    27361 tatactacga tcattgttct gatatactta ttagtatacc gaatatttca atacgggaga
    27421 agggtgatta tgcttcaatt aaaagatata aaaaaatatt ataaagtcgg cgaaaccacc
    27481 accaaagcat tggatggtgt gtctgtcgct ttcagacaaa aagaattcgt agcgatttta
    27541 ggtcctagtg gttctggtaa aacgactatg ctgaatgtga ttggtggact agataattat
    27601 gattccggtg atatggtaat caacggaaag tctactaaag actttaagga cagtgactgg
    27661 gatgcctacc gaaacaactc tatcggtttc atttttcaaa gttacaactt gattggtcat
    27721 ctaggcatta ttgaaaacgt tgaacttggg atgacattaa gtggtgtttc taaagacgaa
    27781 aaacgaaaac gggcagaaga tgcattgcac cgagtcggct tgacaaatca tatgcataaa
    27841 aagccaaatc agttatctgg tggacaaatg cagcgagtgg ccatcgctcg agcactagcc
    27901 aatgacccag atatcctttt gtgcgatgaa ccaaccggag cgttagatac agaaacaagt
    27961 atccagatca tggaattgat ccaagagtta tcgaaagaaa aattagtgat catggtcaca
    28021 cataatcctg aactggccca tcaatacgca gatcgaatca ttgaattttc tgatggtaag
    28081 atcttaacag attcccatcc tcacatcgaa cgaccaaaag atgatcaatt taacttacgc
    28141 agaacaaaga tgagtttttg gacagcgtta aagctttcct tcaacaatat ccgaacaaaa
    28201 aaaggacgta ctttcttgac ctcctttgct tccagtattg ggatcatcgg aatcgcgatc
    28261 gttctgtccc tttcttctgg attccaaaaa caaatcgata acacgcaagc tgaaacgatg
    28321 gcgaaatttc cgattactat ttctaaggta acgactaacc agactcgtga cgatgccgga
    28381 ttgggtgcaa gcaaagcgga ttatccagac agcaaaacga ttactgcaaa agtcagcgaa
    28441 gaagataaag cacagcacac gaataagatt gatcaaacat acgtcgatta cgtaacagac
    28501 atcgatccta acttaagtaa taatatcgga tttacccgta ctacaggaat caatctttta
    28561 cgtgatgtaa atggcaaagt acagcctgtc agcttctcga atcaaaatcc tgatacggaa
    28621 tctctttctt tatctagtac gatgtcagca atgacaggtg tgggagtgtc aagtttccct
    28681 acacagcttg acactagcaa agaaaacttt ttaaaagaca attattcttt acttgccgga
    28741 agttatccag cctcagcaac agatgtcgtg ctgatcgtag acggcaataa taatactaat
    28801 atcaacgcat tgaagaatct tggatttgat gtgaaagaag acgaaaaact tgattttgat
    28861 gatatcgttg gtacaacatt caaattagta aacaacaata cttactatac aaaacttcca
    28921 actgggaatt ttatccctaa tacagattat gatgcgatgt atcagaatgc ttctgatgaa
    28981 ttgaagatct cggggatcct acgcgtgaaa tcttcttcta caatgaatct cttatctcca
    29041 ggaatcgctt atagcgatca attaacgact caaatcgtca acgaaaacaa agaatcagaa
    29101 atcgtcaaag ctcaaagaga cagtggtgta aatgtcttaa ctactgaaaa agttgacgaa
    29161 aatgccaaac aaacattgct tagttattta ggtggagaca gcttgccttc aagtatcatg
    29221 atttatccga acaattttga agacaaagaa aagatcttgg attatctaga tgattacaat
    29281 aaaggcaaat cagatgaaga taaaatcatt tatactgatt tagctggaac gatgactgaa
    29341 ctgactggcg gattgatgga tgctatcact tatgtcctta ttgcttttgc agggatctct
    29401 ttagtaacaa gtatgatcat gatcagtatc attacttata catctgtgat tgaacggaca
    29461 aaagaaatcg gtgtactaaa agctttaggt gcacgtaaaa aagacatcac tcgcgtattt
    29521 gacgcagaaa cgtgtatttt aggtatttct tctgggatat taggtgtgtt tattgcatgg
    29581 ctagctacgt tccctatcaa tagcatctta tacaacatga cggatctaaa aaatgttgct
    29641 caactaaatc ctgtccatgc gattattcta gtgatcgtct ctactatatt gacgatgctt
    29701 ggcggtcatc ttcctgcacg aatggcagcg aaaaaagacg ccgctatcgc tttgcgtgca
    29761 gaataaggtt gtgacaacca catttagatt tgagtcataa gagcgctgaa atagtagaaa
    29821 acagcaagaa acgaggaagt aatatgttcc ttgtttcgcg ctgttttttt taattatttt
    29881 ttataattct ggtatacttt tctttccttt gtaccacaac tcttctggcg tatacctgtc
    29941 ttttccattt atgaatactg ttccatctgc ttcaatcgtt acttcagtcc caatccacat
    30001 attacgagaa agtgcgagaa gattttttct ttttcctctt cctttttttc caaattgcaa
    30061 ggcatcggtt atctcttctg tccaatgaga tttcacgtat tttacttctc cgttttcaaa
    30121 tgtaactttc aaaatattcg ctatattttc cacttttact gctttaggaa atgactcctc
    30181 catttttttc actttccttc ctccaacact aagtatgcgc tttcttttag tgataagtat
    30241 atcatagttt attctattat caaaaaaacg catccattcc attgtagaat actttaccga
    30301 acaagttgaa ttgttttcct ctttttcacc ttttactata gataggtaaa gacaactaag
    30361 gaggaatctc tcatgacaga tcaaccgtat gatttaagaa aagtcatcga agaactaaaa
    30421 acacttccag gtcaatatca cgaaacagat attgaaatcg atcctgaagc agaattatct
    30481 ggtgtttacc gttatatcgg tgctggcggt acagtaaaac gtccgactca agaaggacca
    30541 gctatgactt tcaacaatat caaaggtttc cccggcacac gtgtgaacat cggaacaatg
    30601 gctagtcgta aacgtgtagg tgaaattttg caccatgatt atcgaacact tggtcgtttc
    30661 ttgaaagacg ctgtagaaaa tccaatcaaa cctgtgaaag tagacaaagc agacgctcca
    30721 gcacaagaag tcgttcatct agctaccgat gcagacttcg atattcgcaa cattttgcct
    30781 gcacctacaa atactcctga agatgctggt ccatacatca caatgggtgt agtcttagga
    30841 tcagatccag aaaaaacaat gagcgatgta acgatccatc gtatggttct agaagataaa
    30901 gatacgatcg gtatgtacat catgcctggc ggacgccaca ttggtcactt ccaaaaacaa
    30961 ttcgaagcct tgaataaacc aatgcctatc actatcaata ttggtttaga tccagcaatt
    31021 gccattggca cgactttcga accacctacc actccacttg gctacaatga actatggtgt
    31081 gcaggagctt tgcgtaacga acctattcaa atcgttgatg gtatagcagt cgatgaagtg
    31141 ggtattgctc gtgctgaatt catcattgaa gcagaaatca tgccaaatga aacaatgcaa
    31201 gaagatatca acacgaactc aggaaaagca atgccagaat ttcctggcta tactggggat
    31261 gctaatccag ctgtacaagt agtgaaagtc aaagcagtta ctcaccgaaa agacaatcca
    31321 atcatgcaaa caacgattgg tcccagtgaa gaacacgtat ctatggccgg tattcctaca
    31381 gaagcaagta ttcttgcctt ggtcgataaa gctattccag gaaaagtagt aaatgtctac
    31441 aatcctcctg caggtggtgg taaattgatg accatcatgc aaatccgtaa agaaaacgaa
    31501 gcggatgaag gtattcagcg tcaagcagct attcttgctt tatcagcctt caaagaattg
    31561 aagacagtca ttttagtcga tgaagatgtt gatattttcg acatgaacga tgtagtttgg
    31621 actttcaaca ctcgtttcca aggagataaa gatatcatcg tgatcccagg aatgaggaac
    31681 catccattgg acccatcaga attaccagaa tataatcctg gctctattcg tttccgtggg
    31741 ataagtgcaa aaactatctt tgacggtaca gttcctttcg atatgaaaga acattttgta
    31801 cgtgcaaaat tccaagaagt agaagattgg gaaaaatatt tgaaataatg aatgatctgc
    31861 aactgttttg acatcataaa aaggagtgcg gaaaatggaa caattggcac aacggaagaa
    31921 aaaaatcgtg attggtgtaa gtggcgcttc aggcaccatt tatgccatca acctagtgaa
    31981 gaaactaaaa gaatatccga tgatagaaac acacggaatc atcagtccat gggcaaaaca
    32041 gaacttaaag ctggaatccg acttatcact aactgaattc gaaagcctgt ttgattacca
    32101 ttattcaaac aaagatttag gtgctgctgt cgccagcgga tcatttttga ccgatggaat
    32161 gatcatcgta ccggcaagta tgaaaacagt cgcaggtatc tctgttggtt taggcgacaa
    32221 cctgattgca cgtgctgctg atgtaacaat gaaggagcaa cgaaagttag tcattgttcc
    32281 tcgtgaaacg ccattaaatg ccattcactt ggaaaacttg actaaattag cacgactagg
    32341 tgtgcaaatc ataccaccaa ttcctgcttt ttataatcag cctcaaacga tccaagatct
    32401 tgttaatcac catacaatga aacttttgga tcaatttgaa attgtaaatg agcattcaaa
    32461 acgttggcag ggtgattaat atggaaaaag aaacgatagt tgaagtaacc aaactaggtt
    32521 tcacgatcca agctgctgtt aaagtaatcg gtaaagactt attgatcact ttaacaggcg
    32581 gagatacacc acatatcgga acagtcacta cattttctcg tgatacagag atgcaaactg
    32641 tacgtttccc tagccacgat ggtcggttcc ataaagacga tgtcttagcc gaaaaaatag
    32701 ctgtgatcat caaaactgcc gttccgggaa gttgtacgat cacttccggt atccatgttg
    32761 accatatctc caatgcacaa atcaacgcct cttttccgat gtcagaagag ttaggttaca
    32821 agattttaga ttggttggaa aaaatagatt tccatatcaa ataaccagtt tattataaag
    32881 atggtgaaaa accattatga aagaagaggt tgtgaaatca gcgttatgac ctgagtatga
    32941 gagaaaaaaa tggaaaaata gcttctcata ttttgccgtt tttgagctaa taccgaggga
    33001 cagctgattg aacgccgttt atcaagaggt tgtgataaag ccgcttcgtt tcgagtagta
    33061 agaaaaattt tgtaaacatg ggtttccaca tttttgcata aatttgactt actaccgaga
    33121 aactggcttt tgaacaccgt ttatcaagag gttgtgacac gtcttttgtc acaacctctt
    33181 ttatttttgc ttcactgtaa ctgctacaat atcaccgatt tcttttccga tgtttttacg
    33241 aatatctttt cgtagtccaa ggatgtagca gactgaacca tctggatttt tcacgcccat
    33301 attcacgata ctgccttcat acggcacatt gtcaaaagtt gcttggactt taactcttcc
    33361 agcaccgaat tcttttctta tatcatacgg aaaaataata tatgccccgc ccttgccgac
    33421 ttcggaagca tagatttttg attcaaaaga ataaatttcc ctcattttat ttctcctatt
    33481 ttttacatct agtatagcat agcaaaaaaa agaaggaact gtgacaaaag tcttgtcgca
    33541 gttccttttt tcgaataaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatag
    33601 tcaacaaaca tgagaagctg ttttttgaaa ttgctccttg tgactcagag ttaaacggca
    33661 ggctcacaac ctcttcctta aacggtgttc aaaagcttgc atctacggca ctaagcccaa
    33721 tcagatgaaa aatatggagt gctattttta tctgattgtt cttactgctt gatgcagagc
    33781 agctttttca caacctccta catggtgttc aaaatattat tcgccttttg cttctttcac
    33841 taattttgcg aatgcttgtt gttggaattc agcagctaag gctttcgtac gttgttcttg
    33901 ctctgctttg ctcatttttg gattttcagt cattgctttt accataccgt cttgaacata
    33961 agcttttgct tcactttcca tcgtactttg ctgtttcttc actaattcag ctaacttggc
    34021 tgcttggtcc gtacttaatt ctacccatgt ctctgggatt ttgaatgtat tcactcggct
    34081 gtcatattcg tgattgttat cagcaatatt gaaccagaat ttatacatgt cgtttttgta
    34141 ttcccaataa gtagttttcg tcactttttc agcatcgccg tctgtctttt ctactttatt
    34201 tgtttcgtta tccgtaccag ttgcttttgg tttttcttgt ttttcatttg ttcggtaaag
    34261 atacactttt tcttttccat tccctaaagc tttatacaaa agcatatctg ctccttggga
    34321 atcagcactg gaaacaattt tttctgtttt tgtttccgtt actttttcca ttccaaagtg
    34381 attggacaaa ttagcgacga tcaaacttag tgaagcgacg aagattagtc cgaaaatcaa
    34441 agataaaaag gtttgccatg tttttttagc gaacacgttc gttaaagcaa aagcaagcaa
    34501 gctgacaatc aaaactccaa taatcatgca ttatcccccg ctttcattag aacaggttct
    34561 tttttcttca ataaaaaggc aataataaag ccaagaatcc caaagatgat cgctacgata
    34621 aacgcggcat ggtaacctga cagtgtggca ttgattgcct gatctttata agctaatggc
    34681 gtattatcca atacagattt gcttgggata tttgcttttg tcacattcgt caacacactg
    34741 atcaaaatag ctgtaccaat cgagcttgcg atttgacgga atgtattatt taccgctgtc
    34801 ccatgactga tcaagttatt tggcaatgca ttcataccag aagtcgttac cggcatcatg
    34861 accatggaga tcccaaacat acggatcgca taaaggatca cgatatataa aactggagtc
    34921 gtttttgtca agaaagcaaa tggtgcagtt gccgctgtca aaatgaacat ccctgtgatg
    34981 gctaaacgtt tcgcgccgta tttatcgaaa atcgcacccg tcacaggcat catagccccc
    35041 atgatcaatg cacccggcaa caacatcaag ccagaatgga atgctgattc tccacgaata
    35101 ttttgaatat acaatggtac gaccatttct gcccctacca tcgccatatt tgttacacca
    35161 gctaaaacag ctgcaatcgt gaatgtagat gatttgaata cacgaagttc caagaatgga
    35221 tgttccaaat gtaattgacg ccatgagaac aaggcgatga aaatcacacc aacaactaag
    35281 aaaccaatta ctttcaagct tccccagccg tcatctccta cactagaaaa tccgtaaagt
    35341 aaactaccga atccaatcgt tgataaaata gcggataaaa tatcaatgct aggatttgac
    35401 aatggaataa cacttttcat taggaagaat gctaaaacca agacaagaac aacgattggc
    35461 agtaccatac caaacaagtc acgccaatgg tagttatcaa tgatataacc agataatgta
    35521 gggcctaaag caggagcaag tccaataacg atccctgaca tccccattgc tgatcctctt
    35581 ttttctggcg ggaaaataga tagcatgata ttttgcaata atggcatcga tactcccaca
    35641 ccgcaagctt ggatcaaacg accgattagt aatgtactaa aattaggtgc tgtaaagcaa
    35701 gtaatcgttc cgatcaaaaa gatcgtcatg gcagaaagat ataaatttct tgaactgaat
    35761 ttattgatca gccatgctgt tattgggatc atgatcccgt tgactagcaa gaaaccagtc
    35821 gttaaccatt gcacatcaga cgctgaaata tcgaaagctt tcatcaatgt aggaaaagct
    35881 gtcgtcaata aggtctgatt caaaacggta caaaatgtac caattaataa gacaacaact
    35941 aaaagtgtcc gattatatgg ttttccgtaa atatctacgg gttggttgtt actcatattt
    36001 ctccttcttt ctgaattttt tctgaaacta ctagaatact ttagtcctaa attcgctatt
    36061 tgtcaaccta cttgacacat aagttaatac ggatataatt aagggaagca agaggacaaa
    36121 aggagtgaca aaaatggttg gggcttccct taaacgtttg ttggaaaatg atcaattggt
    36181 tgttggcatc agtgaattaa gtgatatcgt aggtgtgtct ccacgtcaat taaggtattg
    36241 ggaacaaaag ggattcattc gttcgatcga agctgatgcg aattgtccta gaaaatatcg
    36301 tttacctaca gtcataaaag tagaactgat caaaaaatat ttagatgacg gatttacttt
    36361 gtcaaaagct gcagaaaagg cagaaatccg ccaaaagaaa atgcaccatg tccgtaaagt
    36421 tttttcaaaa gcaatcaaag atatcgaatt gatcgacgaa cgctatacga ttttacaaat
    36481 cggtaacttc aaagaagaga atgctaagat gtacatcatt catgacaacg agacagacga
    36541 attaacttac aagctccttc ctgtcgatga aaaagctgac tacgaacagt tgttaaaaga
    36601 actctaaacg ccactaatct cctaagtacc aagcttttta ataagtagat gctacataaa
    36661 tacttgaaaa aaggcctgtt tgaacataag aatatccgaa cggtgatctg cgtttctttc
    36721 atatagaaag gaattctcca tcactgttcg gatatttttt tatttttttc ggttactttc
    36781 ttctaataca tctgttagcc aatttgcata ttctgtttcc cgattgatcg catgcgctaa
    36841 aatcaggtag tgtccgtaat tttcatgttt ttctttttca gtaggaaaga tcgttttttt
    36901 tcgctctaat agatgaagtc gtttttcttc atgaaggtca cgctgctgct gaataatttc
    36961 tactaatgcc ggatcattca cgtctttgac gaaatacaat ttcagaacaa attcgtctcg
    37021 attaaccggt agttcattgg tgggtgtatg aatccactct gccaattgtt ccttcccttc
    37081 ttctgttaat tcataaactt tcttttccaa tttttcacct gtgatctcta cttgatgctg
    37141 aatgattcct tgctcttcca tttttgcaag ttcaggataa atctgactat gttttgcttg
    37201 ccaaaattct cctatttcat ttttgaacga ttgattcaat tcatatcctg tcatcttctt
    37261 cttacttaat aaccctaaca aaatatatcg aagtgtattt tttcttgcca tcagttttcc
    37321 ctccttgaca aatctttaaa tccattctat cataaatgag taatcgaaaa catgtagttt
    37381 attacatgtt ttaatttata aggagatgct taaacatgaa agaatttaaa gaattggaag
    37441 attttattgg aactcacttt atctatacgt atgacaatgg ttgggaatat gaatggtatg
    37501 ccaaaaatga ccatactgtt gattaccgta tccatggcgg aatggtcaaa ggccgttggg
    37561 taaaagacca agaagctgat atcgttaaat tgacggacgg cgtattcaaa atcacttgga
    37621 cagagccaac agggacagac gtggcattgg actttatgcc aaatgaaaag aaacttcacg
    37681 gaatgatctt tttccctaaa tgggttgaag aacatccaga aatcactgtt actttccaaa
    37741 acgaacatat cgcagaaatg gaagcagctc gtgaaaaata tgaaacttat ccaaaattac
    37801 ttgttcctga atttgctacg atcacttata tgggtgatgc aggtatagac aatgaagatg
    37861 ttattagcga agaaccatac gatggaatgc cagatgatat ccgtagcgga aaatacttcg
    37921 atgaaaatta taaacgagta aaataaggtt gtgaaagaga ggttgtgaaa tcagcgttct
    37981 gacctgagta ttagagaaag aaacggaaaa atagttcctc atgttttgcc gttttttgag
    38041 ctaataccga gggtcagctg attgaacacc gtttatcaag aggttgtgaa atcagcgtta
    38101 tgctttgagt aataagaacg ctagttagaa aatagctttt catattttct aggctagtgg
    38161 gcttattacc gagaagcagc cgtttgaaca ccgtttatca agaggttgtg aaatcagcgt
    38221 tttgacctga gtattagaga aacaaatgga aaaatagttc ctcatatttt gccgtttttt
    38281 gagctaatac cgagggtcag ctgattgaac accgtttatc aaagattgta acaactgcat
    38341 attcacacag ttaaattagt gacttcaaaa tgaaataatg ctcccagcaa aaaattaggc
    38401 tgggagcatt atttcgttat tctgttcatc aaaaatcagc gttttgattc catttcatca
    38461 caagttcctc ctcatttact gcttcatctt tttgctgtgt ttgaattgta aaaccttgtg
    38521 aaagatagaa atgaatagct gattgatttt tttgatagac tgtcaaagtc agtgttttat
    38581 tggtttcttt tatttttttc attagttgcg taccgattct ttgttgccgg tattcccttt
    38641 tcacaaagat tcctgcgata aactgatcaa tcaccccagc aaaaccaata atttcttgat
    38701 ctatttctgc taagtaaatc actgcatctg gtaaagcttt cctaacagat tctacttgat
    38761 tctcccaata agttgatgga atgaattcat gagaatccaa gttagcatgc agccaaatcg
    38821 atagaacaga ttccagttct ttggcagaca attttgttgt tgtgcggatc attttttctc
    38881 tccttactta ttcattgatt ttaaaataaa aaccattttt ttgaagctct tttacaagtt
    38941 ttcgcccctc aaaaaagtat atcttctctt gttttacttt tctaatacca aaagaaacag
    39001 caactttagg atcatcagct gaaacgattc gataagttcc accaggcaat tgatccagct
    39061 tgactttccc atgatggtcg ctttgtactg aaaacggcac accatttcta gtaagtgttt
    39121 ttttcttatg tttcaaaatg aatgaactac catttaccgg tttccctgac gaatcactaa
    39181 taataaatga aaaatcaagc acttttttac ttaatctata ctgatagatt agtcgtccga
    39241 taaacactaa cagtatgact acagctatta tcgttcctgc aagaataaac cattgccgca
    39301 tggttctttc ctgatttcct tttccttctt ctttttttac cgattcgtta taaggaatcc
    39361 gatgtcctgt cactagcaaa cgatgcgtgt tgatcatata cggcgtacat gtaagcaagg
    39421 taactaagtc ttctccttct gaaatcgtta gaacagacgt gtcatctggc agtaccactt
    39481 gtatattttt aacttgataa gccaatttct cccccaaaac agtcaaaata aacgtgtctc
    39541 cgttttctaa acgatctaat tcggtaaata accgtcgatt aggtaaaccg ctgtgagcag
    39601 agatcactga atgcgtcgaa tttccaccaa gcgggaaaga ggttccttgc aagacgcctg
    39661 ctccattttc aaggatccta ccattgagcc gatcataaag tgaaatattt aattggatct
    39721 taggtatatt gatacttccg atcagccatt cctctaattg gctggatgtt gtactttcat
    39781 ttctgttctt ttcattgaaa ggatcagtac caggattgaa tccttggtca gttaatcgtt
    39841 ggtttttctc ctccattttc tttcgctgca cttcaatttc agctgcggtc cgtttttgta
    39901 cttgttcgat acgtttttga tcaataaaac tatttaaaga atccacataa aatggatata
    39961 aagcgatcag taaccctacg acgatacata ttaataaaaa caaacgaaac aaaagtcgac
    40021 gagactgttt ttgcttactc tgcttcacat gtgtcctccc ttgcaagttt ttttgttctt
    40081 tcttttatta tatgggttca ggaaaaaaat agaaaatgaa agccgatgag gttgtgaaaa
    40141 agctgtcctg catcaagtaa taagtacagc ccaaaaaaat agctactcat attttttgtt
    40201 gggttgggct tattaccgca gatgcaagct tttgaacacc gtttaaggaa gaggttgtga
    40261 aaactgcgtt atgctttgag taataagagc gctagtcaga aaatagcttc tcatattttc
    40321 taggctagtg agcttattac cgagaagcag ctgattgaac accgtttacc gagaggtcat
    40381 gaaaaagcta ctttgtttcg agtattaaga aaaattctgt ttcaaaacaa ggagatgcaa
    40441 caaaacttat gtcgcatcct ctctccttag aactttcact tatgtttttc ttgtaaaatt
    40501 cataaatatt ttcatgaatt ttctaatttc ttgcctacct ctcgcatagg atatatgatg
    40561 aatttatcta aagtttgcaa aggagttcga caattgaaaa aatatggccc atttttagca
    40621 atttttttca ttgctttggc atttctcatg cctcatttat tcacacataa actaattttg
    40681 ggtgctgatg ccccattcca ttacaatcgg ttctatgatg ccgcgcaaca aattaaatat
    40741 ggggatttcc attattttcc ttccctttat ggattccagc aaagtggcag gatcgtgaat
    40801 gccgtttacg gcccattttt cgcttattta caaggattga tcgtgttgct tgcaggtagc
    40861 tggtttcatt atcagattct ttcaaatttc attctttatc ttatttcagg attttctatg
    40921 ctgattttac tgagatatgt caatgttcga aattgggtaa gtgtaccagt agccgtttta
    40981 ttcatgagta cgtattctat tcaatactgg tctatcaacc aaggattcac tagctggggg
    41041 acttgttttt atcctttatg tatgatccct attgctgatt tcgtccttca taaaaagttc
    41101 cctgttatca aagtcgctgt ctcagtggga cttatgacac agatccattt actgtcttcg
    41161 atcatgttag ctttgatgta tatccctttt tatctttatt acttttttaa ccagactgaa
    41221 aaaggaaaag cactgcttca actgattaag tcggtcttgc tttattttgt tctgacagca
    41281 aatatttggg caggattagc tattgtttac agtgggaata agattcttcc tccctttgtt
    41341 aacagagaaa tgagtcaaaa ggcgatagat ctggatggca gttattggct ccattaccct
    41401 aaggcctttc ctatattgat attatcaggt tttttgcttt ttattttctt tcaacaaaag
    41461 aacaccttat tccaaaaaat cgtgttgtac acaagtcttg ttttcttttt tctttctact
    41521 agcttgattc catggacgac attgatcgaa aaaaatgtgc cttttattag tttgatccag
    41581 tttccatttc gatttttcgt gccatttacg ctattgcttc tactttacct tgccctttca
    41641 ctgaaccagt ggtctgaaca aaagtggttc cgtcttttaa gtatatttgg cattcttatt
    41701 ttttcagcac agacgatcca gaacttatac cagcatctgg aaaagtggga aaatgaaaca
    41761 tttgtcagtc gacatactta tctattcgat acgccggaag aagcaaggaa aacattcttc
    41821 agcaaagata tgtctaccag cttgttcgtt ttccaaaaaa ccacacctga ctatctgcca
    41881 atctataagg agacaaaaga caataaatac gaccggtata acgaagaaat actagaaaac
    41941 gaaacaactt ttataaaaac acatccaggc ggtcttttga caatcaagtg gaaaaacact
    42001 ggggacaaaa ctgttcatat ccctgttatc gtctacgatc ggactgtgct acagcaaaat
    42061 ggaaaaacat tgactgatta tgaagtaaca gatatcggga ccccaatcgt gaagcagcaa
    42121 aaaggaatca acgagctcac gcttcattat caaacgccaa tctatttcta tttcattctt
    42181 tctcttactt tgattggctg gtttaccttg ctatgtttat ttatttatca tagatacaag
    42241 cttttacgtg cttaggcaaa agggataaat acatccgatc aaaaaactct ccaaacggta
    42301 taatcgtttg gagagtttta ttttaatcag tttttttatg ttatatgtta tattttttat
    42361 tcgttcacat ctaattcgat ttccaccccg tagtgatcac tgatgattgg actatcgatc
    42421 ccatcaaaaa tccgttgata ttttttaacc tgcattcctt cagggacgaa aataaaatct
    42481 atacgcaatt tttctgtatt ttgttcccaa ccatctattt tcttttccac agtagctgct
    42541 tttccttttt cattcgcgac aacatacgaa tcttgaagaa gaaggcaact ttctcttaca
    42601 gtataataac cttgagagtc tactggatta ttgaaatcac ctaggaaaaa aagtggtacg
    42661 cgagtttcca aaaagtagtt ttccaagttt ttccactcaa aataaaagcc acttttttta
    42721 tctgtccacc aagaaaagtg gcagctcgag acaaaaatgt cctgatcatc tatctttgtt
    42781 ttcccaatca agatcttgcg tgtctgataa tcttctttct tttgaaattg ggagacggta
    42841 aggacctgac tttccaatgt ttttttcgta agcagtgcat ttccttcttc atatttatca
    42901 taaccgatgt ggctcatttc ccaactccaa aaatactctt ttccgtgttc ctttaaaagc
    42961 tgaactaaac ggtaggcaaa attatcttta cggataggta cttgattctt taccggacag
    43021 aacttcatta gcttcgcagg ttctacttct tcagattcca gtaattggtt gatttcttgt
    43081 aaagcaatca cttcataatc ttctaacagg atcttatctg ctaattcttg caattttttc
    43141 tctggttctg gctcaagcca gctatgcgtg ttgagtgtca tgaatttcat tggttttctc
    43201 cttgtcttca tttcgaaaca aaagggttgt gacaaaattt ttgtcacaac ctctccagca
    43261 aatagtgttc tcctgctaac tcctcagtaa taagctcaat ggaccaggag ctattttttg
    43321 tttggctgtt tttatcactt ggtgcagggc agctttttca cgacctctcc actaaacagt
    43381 attcaaactg ctgcttctcg gtaataagcc caaccaaacg aaaaatagga ggagctattt
    43441 ttgtttggct gttcttatga cttgatgcag gacagctttt tcacaacctc tccttacatt
    43501 ttaatggagc cgatcacttt accagctgtc actgtaccta attgcttgat cactacttct
    43561 tctactttat cgtttgtaaa tacgatcatg atcgttggat ctttttcttc gttttggatc
    43621 acatcaagat ccatctcagc taatttcgtt cctgttccta cttcttggcc ttctttgaca
    43681 gcaatctcaa aagctggctg attcatttgg actgtatcga ttcccatatg gatcaaaact
    43741 tcgataccat ctttcgtttc cagcccaatt gcatgtttgc tagggaaaat acttgtcact
    43801 tttccagcga tcggcgcaac aacttctctt gatgttggaa taacagcaaa gccgtcaccc
    43861 atcatttttt gtgagaatac cggatctttt acttcagata aaggaatcac ttctccagaa
    43921 gctgcggaaa ctagttcttg ttctatacct aagtattgct tactacctgc ttgtccattt
    43981 cctgtagaaa ccatttctgg ctctggaatc tctgctcctg attgcagcag atcttcgata
    44041 tctgatttca agacatctgc ttttggtcca taaactgctt ggactccatt gtctttgacg
    44101 atcaatccca tcgcccctgc tcgtttccag gcttcttcag tccctacttt ttctcgatca
    44161 tttacactta cgcgtaaccg agtcatacaa gcatcgacat ctttgatatt ttcttttcct
    44221 cccagcaaat gaatgatctg gaccacttgc tgatctgctg ttcctgttcc gctgttagat
    44281 acaacggttt cttcactgtc attgtcgtaa tttccgttac gtcccggtgt agcaaagttg
    44341 aattttttga tcaagaaatt tgctaagaaa tacgtaacaa caccaaaagc gatcacacac
    44401 aacacgaagt tgataagatc tccacctaga cccgctttga tagctaacgg tgtccgagtc
    44461 agcaattcga tattcccaaa tgaatggacc cgcaatggca agatatctgc catcgcaaat
    44521 gcagcccctt ggatcactga ataaatgaca tataatggca cagcagcaaa cataaacatg
    44581 aactccaatg gttctgttac acctgttaga aagacagcca acgctgctga aaaatacatt
    44641 gatttatatc ttgctttctt atcaggatcg acattacgat acatcgcaaa agccattccc
    44701 atcaagatac ctgaagaacc aatcatttgt cctactttga aacgagccgg cgtccagtta
    44761 tgcaacacaa actcatattg cgacatatcc cctgcacctt taagattcac taaatcagtg
    44821 gcccaagcca accataacgg atcttgccca aatacttgtg tccccgcctg tgcgcctgat
    44881 aaaatctcat acgatccgcc aagctgtgta tagttgatag gaatcgtcag catatgatgc
    44941 aatccaaatg gcaatagtaa acgttctaat gttccaaata aaaacggtgc tagaatcggt
    45001 gcgctttctt gtgattctgc aatccataaa ccaaaattat tgattccagc ctgtacgttt
    45061 ggccacacca cagcaagaat caatgccacg attgttgacc ataagataac aacaaacgga
    45121 acaaagcgct ttccattgaa aaatgacaaa gcatccggca attttctata attatagtac
    45181 ttattataag ccattgcccc gacaaatcca gcgatgatcc ctacgaatac tcccatattc
    45241 aaagctggtg cttccaatac acttgtaaaa aatcctttaa ccatgatctt cgtaccgaac
    45301 agagtgtggg taaatgcatc ttcattcgca agcatgtcac ttgtgacacc aaagatagcc
    45361 ccagtgatcc gattgattaa aataaatgag atcccagctg caaatgctcc gcctgctctt
    45421 tcttttgccc aacttcctcc tattgctaaa gcaaataaaa tatgaagatt accaataatt
    45481 gcccaaccaa tattttcaat tactccgccc gttgtgacaa gcggcgtcca atcaggattg
    45541 atcaagggaa ttgatttccc tatactgatc atcaacccag ctgccggcat aactgctacc
    45601 acaaccatta aagcctttcc aaatttttgc caaaactcaa aactaaatat ctttttcatt
    45661 ccgtttagct cctttacgca atcggtttcg ttaaacgtat tatagcgtgc gttttctttt
    45721 ttgtaaatgc tttatttttt atttttctgt ctataccatt ctataaaacc tataatacgt
    45781 gtgttccctt ctataatttt ctcctaaaaa tttatttttt taagcttttt tctatgaaat
    45841 attttctttt gtctattgac ttgtgcaatc ggttgcgttt attatgaacg tataaaacag
    45901 ctcattagga ggagaaaaat gaaacagatc aaacgactat ttgctattga tccatggaaa
    45961 atcagcacga cacaattaga taaaaaaaat cttcgactgc aagaatcttt aacaagtatt
    46021 ggaaacggtt atatggggat gcgcgggaac tttgaagaaa cttactcagg ggaccaccat
    46081 caaggtactt atttggcggg tgtctggtat cccgataaga cacgtgtcgg ctggtggaaa
    46141 aatggttatc cagaatactt tggaaaagtg atcaacgcct tgaactttat cgcgatagat
    46201 atttcgatca acgatcagct gatcgacttg gcttctttgg aaccagaaga cttttactgg
    46261 gaattagata tgaaaaatgg tgtattatct cgtacattca caatcactac ttctactaat
    46321 aaagtacgca tttccttcga acgttttctg agcattgtca aaaaagaatc agcttatatc
    46381 tatttaacta tagaaatgct tgaaggtagc ggaacagtca aactcgtatc aaaattggat
    46441 ggaaatgttc aaaacgaaga cagcaactat gatgaacatt tttggaatga gattgatcgt
    46501 ggaactatag aagaaatcgg ctatttgacg actaaaacta ttccaaacaa ctttgggatt
    46561 gaacaattta ctgttactgc agcaatgcgc catttcgtta atggaaaatc agtcatccct
    46621 gactatcacg aagatacttt agcattacat ggttgcttgt ctgcagaatt atctcaaggt
    46681 gagacatggt cagtggaaaa agaaattatc gttcttacta gtagagatat tccagaagcg
    46741 cagcaagcag aaaaagctgt ctcagaatta acgaaccaga caaacaatta tatccaagca
    46801 aaagaagagc aaacagcggc ttgggcagaa cgatggaagc ttgccgatgt ggtcatcgaa
    46861 ggagacgaag aagcacaaca aggtattcga ttcaatttgt tccaactatt ctctacttac
    46921 tacggcgaag atgaacgatt gaatatcggc cccaaaggat tcacaggaga aaaatacggc
    46981 ggagccactt actgggatac agaagcgtat gctgtccctc tttatcttgc tttagccaaa
    47041 cctgaagtaa ctaagaatct gctgaaatat cggcataatc aactgccgca agcaatccac
    47101 aacgctcagc aacaaggatt aaaaggcgcg ctttatccta tggtcacctt cactggtgtc
    47161 gaatgccata acgagtggga aatcacattc gaggagattc accgaaatgg cgcgattgcc
    47221 tatgcaatct acaattatac gaattacacc ggcgatacgg aatatttgaa aaatgaagga
    47281 ctggaagttt tagcagaaat cgcacgcttc tgggcagacc gtgtccattt ttcaaaacga
    47341 gcaaataaat acatgatcca cggtgtgacc ggcccaaacg aatatgagaa caatatcaat
    47401 aacaattggt atacaaatac gatcgcagct tgggtcttgc gttacacgcg agaaaattat
    47461 ttaacttatc aaaaagaagc tgctatcact atcagcgaag aagaactagc caaatggaaa
    47521 gatatcgcag agaacatgta cttcccagtt gacgaagaat taggaatctt tgtccagcat
    47581 gacacattct tagataaaga tctcatgcct gtatccgata ttcccacaag cgatcttcct
    47641 ctgaatcagc attggtcttg ggacaaaatc cttagatctt gcttcatcaa gcaggcagat
    47701 gtactacagg ggatttattt cttcaatgat acttttacaa aagaagaaaa gcaaaaaaac
    47761 tttgatttct atgaaccaat gactgtccat gagtcttccc tttcgccaag tatccattcg
    47821 attttagcag cagaattagg aatggaaagc aaagctgtag aaatgtacca gcgaacagct
    47881 cgcttggatt tggataatta caataacgac acagaagacg gcttgcacat cacttccatg
    47941 actggtagct ggttgtcgat tgtccaagga tttgctcaaa tgaaaactgc ccatgatcag
    48001 ttgagattcg caccatttct gccaaaaact tggaaagctt attctttcca tatcaattat
    48061 cgcggacgtt tattgttcat ctcagtcaca gatgaacaag ttactttcga gttattagaa
    48121 ggttctcctc tagaaattta cgtctatgaa cagtcttatt ctttagcgga tcgtctagaa
    48181 ataacgctaa gaaaggagga agcaaatgtt taaaggggta ttgtttgatt tagacggtgt
    48241 cattaccgat actgctgaat tccattatcg tgcttggcga aagcttggtc aggaaatcgg
    48301 cattacgatc gaccacacat tcaacgaaca gctaaaaggc gtcagccgag aagactcact
    48361 ctctttgctt ttagcttatg gcggaaaaga acactctttt tcaaaggaag aatttgcaga
    48421 attagcgaaa agaaaaaacg attattattt agagatgatc cagacgatcg aaccaaaaga
    48481 tgtcttcccc ggggtcgtgc ctttactgga ttctttaaaa gaagaaaaaa tcaagattgc
    48541 tcttgcttct gcaagtaaaa acgggccatt cctacttgaa aaaatgggtc ttacacctta
    48601 ctttgatgct attgccgacc cggcagaagc aacaaacgga aaacctgcgc cagatatctt
    48661 cctccttgca gcaaaagctg tcggactaaa agcagaagaa tgtatcggga tcgaagacgc
    48721 gcaagccggt atccaagcca tcctctcaag tggcgctcaa ccaattggcg tgggacgtgc
    48781 tgaagacctt ggagaggaga tcccgcttgt ccctgatacg acttttctta cgatcgatta
    48841 cttgaaagaa aagtggcatg accatggata atccagagat ctccgtcgta ccagttccag
    48901 agactgaaat aaagaaaatc acattgaaga acgactactt agaagtcgtt cttctcaatt
    48961 acggtgcccg cctgcaccaa atcttcgcac cagacaaaga aggaaaatca gaaaatgttt
    49021 tattgtctta cgatcgtttc gaagatgttc taacagacaa aagctttttt ggagcaactg
    49081 tcggacctgt agccggaagg atccgggatg cttcttgggg tgagcataga ttggagaaaa
    49141 actgcggatc acaccatatc cacggtggca cgaaaggctg gtctttccaa ttttgggaag
    49201 tagaagtttt caaaactcca tcatcaatag gtgtggtctt ttacttaaaa gatgaatttt
    49261 ctacctatcc aggaccaatc actgctacga tcacttaccg tttaacaaaa aacgaattag
    49321 agatgacaac ctctgctagt agccttgttg aaaccatctg caatccgacc aaccatgcct
    49381 acttcaacct ttcaggaaat ggaacaagag acatctatga acatcagtta acggtctttt
    49441 tagatggtgt gcttgaatta gatcaagaaa aactgcctac tggaaattgg acaaaaaaag
    49501 aaaaactgcc aatcgacttt agaaaatccc caacactgca agagatcctt gcatgttatc
    49561 cagatggact agatgatgta tttcttttgc atcatcctag gctttccaaa acttccttac
    49621 aattattcga gaagcattct ggtcgccaaa tgactatagc aacttctaat aaaagtatgg
    49681 tattattttc tacgactgga ttcgaagctg atttctctgt caatggaaaa cagatgcatt
    49741 caaactacgg attagcaatc gaaccgcaag aaatccctga tatcgttcat ttccccaaat
    49801 ttggatcgat caacctccat cctggtcaag aacggatcag tcagacgatt tatcggttct
    49861 ctgcacaata acaagagaaa ggtgttttta tcatggctat taccgtaaaa gatgtggcga
    49921 aaaaagccgg tgttgccacc tcgaccgtct ctcgtgtcat caacgatcat cctagtattt
    49981 ccgagacaac aaagaagaaa gtccgaaaaa ttatggatga actaggttat gttcctaaca
    50041 tgactgcccg caatctagga aaacgcattt ccagtgccat cggcgtaatc ttaccccctc
    50101 ttgattcaaa agagcggatc ggtaacccat tttatcttga gatcatggaa gcaatcaacg
    50161 aagaagcgcg gaattatgat atgactacag caatcgctac tgctaaaaat tttgaattgc
    50221 tgttagagaa cgtccagcgt atgcatttac aaaaacaagt agatggtttt attctagtgt
    50281 attcagatag tcaagatact gtcattgatt atttatacca aaaccacatc cctttcactt
    50341 tgatcggaca gccttatcat catgagaacg aaatcgttta tgtagataat gataaccagc
    50401 ttctaggtaa acaagcaaca gaatttttga tccagaatgg acataagaat atcctgtttg
    50461 tgacaaacac gactcatgaa agtttgtatt tcgaacgata tttcggttat caaaaagcaa
    50521 tgatgatggc tggtcttcct gcgttatcca gtgtagtact agagcatccg gaggattatc
    50581 tgtcctttga gaaaacgttg aaagaaaacg aagccacagc attggtggtc attgacgata
    50641 tcttcgccct tcgcacgatg cagttggcgc aaatgtatgg ctatgtcatt ccagagacac
    50701 tctccgtcat tagcttcaac aactcgatct tctcaacatt aacacaccct taccttacaa
    50761 gtatcgatat cgatatctcc gaattaggac gtgtcgctat gcaaaagctg cgcgaattga
    50821 tccatgaaga attgagcagt ggcgtacgtt tggtcatccc tcatcgcttg atcaaaagag
    50881 agacagtcgt tcctttagaa aacccatact aaatagctga ctcactaaat acgctgacca
    50941 tttatcctat ggtcagcttt ttatgtaaaa gaagatacta cttctaacac attgtttatc
    51001 tgtaaaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta
    51061 taaacggcgg aagcagaagc aactccttcg gaaataagct gaaattcaca aaaatttaaa
    51121 aagcaatttt cttgagtttc ttcttatttc ttggagttaa acgcttctgt cccagcctct
    51181 tttttccttc cttcaatttt ttacacgtcg acgattcaat aaaaaaccgc ctaatattgt
    51241 aaagacaggt gcaagaatcg agaaaaaggc gaatggcaag taatgcaacg cgctaacttt
    51301 catcgttccc ataatgaatg tgccgctgac tccccacggt acgagagaat tgacggtcgc
    51361 acctgaatcc gctagtgttc gtgtcaaata ggtttttgat aagccaacgt catcaaaaga
    51421 acgcttgaat gtttctcctg gaagaatgat ggacagatac tgttctccaa cgatcagatt
    51481 gattccgata cagctcaagg cagtaaaccc gactaaacga gaaggtcggt ccatcttttc
    51541 ttttaattct tgaacgatgg tatcaacgat cagatatttg atcagtaacc cacctaatgc
    51601 caatgcaagt aaaatcaaac tagcagaacc taacatactc atgatcccgc ctcgagaaag
    51661 cagttcatct agctttggat caggtgtatt tgcgacataa ccattcatca agatgtctgc
    51721 tgcttttccg accgtcaaac ttttctcatg gataaaagaa agaacgagag cagctgtcga
    51781 tcccgctagt aatgtaggga tagccggaat ttttttgatt gcccccccaa ataaaataac
    51841 tagtggaatc aatgtccaag gagagatcca aaagctcgct ttcatgtttt ggatcatttc
    51901 attgatacta gctagatcgg ctgaatgact gttatgtcct aatatcgtat aaaaaatcaa
    51961 cgaaaggacg aatgctggga aatccgtata acgcatacca gcgatatgtt cgaatagatt
    52021 aactcctcca atacccgctg ccaagttggt cgtatctgat aaaggcgagc agttattccc
    52081 taaaaaggca ccggaaacga ctgcgcctgt agtcattgca tcattgaatc caagtaaatg
    52141 accgatcccc aaaaaagcaa ttccaatcgt cgaaatcgtt gtaaatgaac tgccgacagt
    52201 cactccgaca attgcacaaa caagaaatgc tgtcggtaaa aagaaacgca cagaaacaag
    52261 tttaaatcca taaaccataa tcgtagggat ggttccagat aaaatccatg aagcaactaa
    52321 gacaccaatc aaaagaaaaa tcaggattgg aatgatccct ggagtgattc ctttgatgat
    52381 cccgtcatgg atctcatccc atgtgaactt tttaaatctg ccataaaaca acaaacacat
    52441 gaaagctgca aggatcggga tatgtggcga gagctggaat ccgatgatca gtactcctag
    52501 gagtgccaac aacacgatca atacagcgat actttctttt aaagaaatat ttttattcat
    52561 cgtcgatctc ctatttcaaa tgaaaaggcc ctgccatgaa aaaactattc acttggcagg
    52621 acctcctact aaatcagcga caaaacgtcg gctgaaagac ttattttttt atttttcttc
    52681 taaacttttt tctacctcaa tcccccaaga atctttcttg aagtgattga tgatcaatgg
    52741 aataacgaac atgaccactg tgatagctgc tactaataat gcatcactca atgtcgctgt
    52801 acctaatgta gcaaatacga caacgatgat agagaagatc agcatgcagc tgactaccca
    52861 agctaatccg tttccgtttt taccaattcg gtaaggacgt tcgaattctg gatgtttctt
    52921 acgcatttta agcaatgaaa cagcaatcaa aatgtacacg atacaataaa taacagttgt
    52981 agcatttgta agtgtcaaga atacagcact tacgtcatcc attacaccat aaagcaaagc
    53041 aaataatgaa ataacgattg attgtgttag aacgacattt ctagatacgc cgtatttgtt
    53101 ttctttatgg aatccgaatt ttggtggaag gaatccttca cgagctactt ggatgattgt
    53161 ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc acaccaataa ataccatgaa
    53221 gctgaagata tttccgatca cttctggtaa gcctaggatt tgacagtcaa tcaagatagg
    53281 ctgcgtgata tttgctaatt ccatttttcc atctggtacg acatttgcta caagcatcgc
    53341 attgatgaca ttcaataaaa ctaatccgat caaagcgata aatacgcctt ttgtataatt
    53401 ttttgttgcg tctttcaaac gaggcatgta aacagaactc atttcgatcc caacaaaaat
    53461 aaatgtgata ccagctaagt atttcaatga atcaatatgt tccaagtcag ggaaagcttt
    53521 tgaccatgaa aagtcaccta gatagccgtt tgagactagt ccgactttga aggctgccaa
    53581 aacacctaaa acgaacatga tgactactgg gatatatacc cctagccata caccgatgtt
    53641 cccgccgact tttgccatat cgaatttcaa gttcaagatc gtgatgatcc agtagataac
    53701 taaaatacaa cctaaaacga accagtgatt attgccaagt tctacattac caaatgtgtt
    53761 tcctaacaat ggtcctaaag tagaagcgac cattaccata cctgggaaca tttgcaccca
    53821 taatagccat gcaacgacaa atccccattt gctgcccagt gctgttttta cccataactg
    53881 aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg gaaaccattg atatcggacc
    53941 ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat gtccaaccga ctgcggctaa
    54001 cgtaggaata ctccgaaccg ttgcacacag tgccattgtc agaccgataa aggtcccaag
    54061 acccatttta cttacttcag atttactcac cgttgacact ctccttgatt ttttggataa
    54121 aataacggtg tctttgaagt agtttcagca ataaacgaaa caattcagcg aatatttgag
    54181 gggattcttt gagtttattg cttgaagggt ttcttcaaag acaacctcaa aacaaaggga
    54241 tcgaagagct taggtctccc cttgctcttc agatccaaac atgcgtcaga aacagttagt
    54301 attcaagctg ttttctaaca tgattacctt gcttattttg cttcgcttgc caataattgg
    54361 tctgcgtaga ttttttccaa tttttcttga agagctgctt tgattttttc agcatattct
    54421 tcaaagtgtt cttctttgtt catgtatggt gtcattacgc tggcacgcaa tacagttact
    54481 tttccggcac ggttccattc ttcatctgag aatcctagtt ggttcacaaa ttgtaatggg
    54541 ctgttgccat agtctgggat agcaaagtca gtatgtgaag ttaagaactc attaccgtaa
    54601 atgcttcctt tcacgtatga agaataatca tatacgtcat ggttcaattt attcattgca
    54661 actaagtcat cgttgccttt ttctttgaat acatagtcta ccatattgaa atctggataa
    54721 gttaatggat gaacttcgat ttctttgtct cctactttaa atgacaagtc attcaagaag
    54781 ttgtagaaac gatgtgcacc ttcgattgat gcacccatta atttaccata tcctgtgaca
    54841 ttcaaaggta agacatggtg tgctgcccaa acgctggctg ctgttgcccc tgcttttgaa
    54901 ccttccaaga tataagcccc aagtaatgct gggatatctg cgcctttttc aaatacatat
    54961 gtcgcaaagt aagagataac gtctctcatg cggatatctt tgatgacgat accaccggca
    55021 gaatatggaa catagcccat tttatgtggg tcaatcgtta cagattctgc ttcttcgatt
    55081 gctttatatg cactgtgtac ttcttctaag atataatctt tgttttctgt aaagacattg
    55141 tatttgtaat gaacatcttt taaatcttca aatggaatga agttgttgtc ttcgtctaag
    55201 aaaatcgcac ggccgtatcc gccataagca gcatctacgt gtaagtagaa gtaaataccg
    55261 tctttttcta atacgcgacg caatgcaacg attttatcga taccgtcgat tgctccttct
    55321 tctgttgatc ctacaacacc gactacacct aggattggtg ttttttcagc tgctagacca
    55381 cgaacgattt tttcaagttc gttgatgtcc atgcgatagt tgtggtcaac tggcactgga
    55441 atcacttggt ctaaaccgat accgatgatg tcggcagctt ttagccatga atagtgttta
    55501 gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt ttccgctacg tgctgagtga
    55561 gctttgattt cgtcgatttt ttctgggacg ctgtctaaca gattcatgat ttcttctgtt
    55621 gacaagttca ttaattccca atcgcttttt ccagcaacta gttcaggtgt cacttctttc
    55681 attgcaagcg gcaatgattt gatgttgcgg gcataccaaa gtccttctaa gtttgctaaa
    55741 gaaccatcag caacgatgtg gccccagcca tctttatagc tcattaattt tgcaaattcc
    55801 attcctactt cttcttccat ttggcttgtt gcaggagaag attcataggc aacgttatta
    55861 ccattccata gcatagcaaa attgtacgct agtaaagatg gcatcaatgt ttcagagttc
    55921 atatgacccc agtaacgtcc ggcattatgc caaggaacgg aatgggtacg catccgcgct
    55981 gaaatttctg atagaacatc ctttgtttta ttcacagtgt gttcaaaact agcactgctt
    56041 ttttcttctg gcgtaataat aggcatgtct tgaggcatgt agttttgacg ccagcctaaa
    56101 tgttcatcca ccaattcatt caacaaagct ttatagattt ggccgttctc agctttgtcc
    56161 ccaatgaata gggcatttag gtttagatct ttcgacaatg attcactcat agtgaaaccc
    56221 tcctaaaaaa atatttaaat tttgtcgagc cctacattac acctgttctt ctattctgta
    56281 aactaagttt tggcctgatt tttaatcata ttttaatatg tatcaattat ccgaattgtt
    56341 cacacttttg aaataattaa aaaaaacgag ggaatttaca aatgtaaact ccctcgcaaa
    56401 gattgtatta acgacaacca gcgttctatt ttaggatggg tttcaaaatt ggaatgttgt
    56461 aatagtattt ccctttttca aggtaaaaac ttactaaatt ctaatcaatt actttggcca
    56521 aaaagtaatt tttcttacct tttcgaataa ccacaaactt accatcgaat tcatcggatg
    56581 gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt aatacttata gctccgtttg
    56641 aaacatcttc acgtgcttga cgtttagatg gttcaatttt tgtggaaaca agcagttcca
    56701 cgatattttc aggtgtgctt gaaatttcaa cgttcggcat tttaccgaat ccttgcgcga
    56761 tttcttccgc atttagttct ttaatatttc cagagaacaa tgcttgcgtt attttttgcg
    56821 cttctttcaa gtcttcttca ctatgcacaa atcttgtaac ttcttctgcc aaacggcgtt
    56881 gtgcttcacg tttctcaggt tctgtctcta cttttttcgc taagtcttcg atttcttctt
    56941 gagacaagaa agtaaagaat ttcaagtatt tcactacatc gcgatcatct tgattcaacc
    57001 agaattggta gaactcaaat ggtgaagttt tcttcggatc aagccaaacg gcaccgcctg
    57061 cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa tgggatcgtt aaaccgaacg
    57121 cttctgcttc tggtccttct aattttcgga ttaggtctaa tccagctgtg atatttcccc
    57181 attggtctgc tccaccgatt tgcaattgca catcgtatgt tttatgcaga tgcaaaaagt
    57241 cgatagattg caggatttgg taagtaaact ctgtaaatga gattcctact tccaaacggc
    57301 tggcaacgat atcttttgct aacatcgtgt tgatgttgaa gtttttaccg tagtctctca
    57361 aaaattcaag taaagagatt tttgacaacc agtcgtagtt gttcacaaat gtgatatttg
    57421 catctttacc aaacaatttt ctcatttgat tggaaagtgc gtccacgtta tgttgcactt
    57481 gttccatcgt ttgcaacaca cgttctgttt tgcggccgct tgggtcgccg atcgttcctg
    57541 ttccgccgcc aatcagaata tatggatgat ggcctgccaa ttggaatctt ttcatcatca
    57601 taaatggaat caaatgtccg atatgcatcg aatcaccagt tggatcaacg ccgcaataaa
    57661 gtgaaatgct cttttcttca acgagctcgc gaagtctttc ttcgtttgtt tgctgattaa
    57721 tggcgtcgcg ccaagttaat tcatcaataa tattcatttt actgacctcc gtgtagtttt
    57781 tttatgaaag caggaacctg ctagcatatg taattaatta tttcttcagg ataggatagg
    57841 aaataaaaaa agtcccttgg catataagcc aagggacgaa atctcgcggt accacccaat
    57901 ttgtatgtct agatatccaa catacctctc gaacatttaa cgctgtcgcg tggcaatcac
    57961 tgccaaagac tcctgaaatg taattcgctt taaagcatgt actggtttgc agcgaccacc
    58021 agctttctga aacattggct ttaacaacta cttcgtttcg atcttcgtct tgttattatt
    58081 aatatgtgtc tatcatagag cgcaactttt tctttgtcaa cagaaaaagg atattttttt
    58141 taaattcctc attttttctt ttttgaatcc gctctaattc cgaacatttt attttcaatt
    58201 attgttaaaa gaaataactt tttctgtatt ttttctgcaa tttatcgaga agtcacttta
    58261 ctttgcctct tattctttct tcgttacaat aaggaatggg acaagtaaaa aaatgaaaaa
    58321 gcaagggacg aggtatatgg aaaaaaagca aaaaattatt ttaggagcca cttctgcttt
    58381 aactatcgtt attttaattc taagtttgtt ttttgtcatc cgatcatcta caaaaaaaga
    58441 accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa gaaccgacag atgataagca
    58501 acaactagtt actcaagcaa aaaatctggc tcaaagctac gattatgacc aagcgattgc
    58561 gttattggaa aaagatagta agaacggatc tactgaaaca caacagcttc ttcaaacact
    58621 aaaaaaggag aaagaacaac tgatcgactg gtctgatcct actcagatct ctcatgtctt
    58681 tttccacagc ttgatcgtgg acccgcaaaa agccttccac tctcaacagg cacaaggata
    58741 caaagattat atggtgactg ttgaagaatt caaccgttcg atcgaacaac tttatcaaaa
    58801 tgattttgtt ttagttaatt tgaatgattt gatccaaaaa gacgaacaag gaaatctttc
    58861 ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg gttctttcac aagatgatgt
    58921 cagctattat gaatatatgg ataattccgg ttttcctagc cgattggtcg tatcaaataa
    58981 caatgaaatc aaaaatgtct ataaagagaa agataaagaa gaaatcggtg actttgacat
    59041 ggttcctctg atcgatgcct ttgtcaagaa acatcctgat ttttcttatc gaggcgcaaa
    59101 aggtaccttg gccctgacag gttacaacgg agttttaggt tatcgaacat caaaatctca
    59161 atatggagac aatgaaaaaa caaaaaaaga gattaaagaa gctaaaaaag tggcggaaca
    59221 gttgaagaaa gacggctgga gctttgcttc ccatacatgg ggtcacttga atatgactca
    59281 agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg cagcaagaag ttgcacctat
    59341 cctaggaaaa acaaatattc tgatttatcc atttggtgca gacatcagcg actggcagcc
    59401 ttattcagca gaaaatcaaa aatttgctta cttgaagagt caaggtttcg atattttctg
    59461 taatgtcgat gcttctacac cagcttgggg acaattaggt acggatttct atcgaaatgc
    59521 tcggatcaat atcgatggca ttcgttttca atctgattta gacggaaaaa atcctattct
    59581 tgatccattc atcaatgtcc atgatgtcta tgacaaagaa gcacgcgaat ctgcttgatt
    59641 ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt atcgtcagtt tcggcttttt
    59701 tatgctttat ttcttcttcg gtgcgattcc cttgatcagg acttctgtcc attctgctgt
    59761 atatggaagc agttttgcgt atatctccgg cttagaaatt ccttctacca ttgcttgaaa
    59821 atagaggatc aagaactcat ccgaatattt caaatccact tttccttctt tccgccctcg
    59881 atggaaaaga tcaagcatga tactgaaact ttcttgcgta tacgcatcca tcgcgtcaga
    59941 aaattctttt ttttcttttt ttgtatagta tgtcatcaaa tcgatataaa attgtttgtt
    60001 cactcgattg agataacgga ttttgttttc actcatggca atcagtgttt cttcaaatgg
    60061 aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa tcattcataa atgcaaaaaa
    60121 tacttcataa atcagccctt ccttgctgcc aaaatattta aaaatcgtcg ctttacttac
    60181 ctgagcgttc tcagctacct tatccattgt cactccagcg gttcctatgt ctgtgttcat
    60241 caagtcaaaa gctgcttgta aaatctcttt ctttttctct tgtgctctct tttcaaaacc
    60301 gttcatttgt agagcctccc gtaattttaa acttttataa tatatatagt tcaaatttat
    60361 tctgaggttt attataacta tctattgaga aagtatcaag ctagcaattc cttgtttatg
    60421 aattcattga cagaaattta taaaaagaat attatgtact aaaataataa aaaaagtttt
    60481 ataaaaaggt ataaaacctt tttattaaac tatttaatct tgtttagtat atatttttag
    60541 aaaaaggagt ggggttttta tggcagaaat cgtcaaagtc acacatttga aaaagagctt
    60601 tggtcgtttc gaagctttaa aagatgtctc tttcaccgta cattcaggtg aagtcgttgg
    60661 atttatcgga ccaaatggtt ctggaaaatc cacgacgatt cggacacttt tagggattat
    60721 aaaaaaagac ggcggaacgg caacgatttt tgggcaagat gtatgggaag atagtttatc
    60781 tatccatgaa cgtctttctt atgttccagg cgatatctct ttgtggggaa atttgactgg
    60841 aggagcgatc atcgatctct tcatgaagct tcatggaaaa gggagtgctc aaaaaaaaga
    60901 tgaactgatt caacgtttct ctcttgatcc taagaaaaaa gcaaaaaact attcaaaagg
    60961 aaatcgccaa aaagtgggct tgattgctgc tttggctgtt gattcggatc tctatttatt
    61021 tgatgagcct acttctggtt tagatccttt gatggaaacg attttccaag aagaagttga
    61081 aaaattgaaa gaacagggca aatccatcct actttcttct catattctca gtgaagtcga
    61141 gcgactagcg gataaagtcg tgatcatacg cgaaggaaca ctcgatgaag aaggaacact
    61201 cgatgaattg cgtcatttga ctcgttcgac catcactata gaaacagaag cagagaatag
    61261 tcacttagca caattgaacg gtgtccatga ctttgtgcaa aaaggtcacc tcgctcaatt
    61321 tgctgctgat aacgaagctt tcgatgtgat tttagctgaa gcgtccaaat taggtgtgaa
    61381 aaaatttgaa tctattccac cgactcttga ggatttattc atgagacatt atgaaggatg
    61441 aggaggaagc gaaatgactg ataaattttc acgctggtcc accctttttt ctcaaaacct
    61501 tagccgtgac tggaaaaaga tcctgatatg gctagtcggt gtcactgctt tttctggtgg
    61561 ttttgtccct gcgtttgaag aattgacttc cggacaagga ttagctggat tatacgaaac
    61621 cttgcaaaac ccggcaatga ttgcaatggt cggaccaact ccagcttcga atgctgctga
    61681 gtatacttta ggagcgatgt atgcaaatga aatgttgctt ttttgcagtt tgtttgctgc
    61741 tgtgatctct gttttacacg tggtgagcca aacgagaaaa aaagaagaac ttggtctgat
    61801 tgaacttatt cgttcctttc gagtcggacg tcaagcaaac tctttagctg tcatcgctga
    61861 aagtattctg atcaatttgc ttttagcaat atcgatcagc tgtacgatga tttttttcca
    61921 agcggattcg atcactgcag aaggtgcttg gctttttggg ctatctgtag gtagtatggg
    61981 gattttgggg agtgccgttg cactgtttgc tgcacaactg atgccaagtt cagccagttc
    62041 gaatggtctg tctttagcgt ttttaggtgg actttacctt ctacgagcaa taacagatgt
    62101 agctgattcc tccctttcga tgtggaatcc tttaggctgg tcttatttga cctatccatt
    62161 tacaactaac aactggattc ctttgcttta tttgtttttg ttcagtctaa tcttgataat
    62221 cagttcattt gttttagagg aacatcgaga tttgaacacc ggctatatcc ccgaacgtga
    62281 aggaaaaccg tatgctaaac gttctctttt atccttgcgt ggtttattat tctatctaaa
    62341 taaagggatg acaatcagtt ggcttatcac ttttggtttg atgggggcgg catacggctc
    62401 tatctacggg aatatgcaac agtttttaga aagtaacgac ttaatgaaac agatgtttat
    62461 ccaatctggc gtctcaattg aaaaaaactt tacaagcacg atcatggtag tcttgatttg
    62521 tctagctgct attttaccaa ttgctagcat caatcgttta tttacagaag aaacccacgg
    62581 acgtatgaat cagctgttcg caacaaaaat ttctaggaac caactttatt ggaccaatat
    62641 gttactagct attctatttg ctatattggc aatcctgatt agttctggtg cactagggct
    62701 ttctgctttg gcttcgatga aggatgcgaa agacatggat ctattgatgt ttcttaaagc
    62761 cgggttcaat ttcctgcctg ccgttttagt gtttatcgga attagtggct ttctattcgg
    62821 atggcttcct cgaatcggta aacttgctta tatctactta gcttactcct ttgcactcaa
    62881 ttactttggc ggaattttgg atttaccaga atggttttcc aaaacagctg tccctagctg
    62941 ggttccacgg atgccaaacg attcttttga tctttccgtg ttccttacgt tatcatgtat
    63001 cagccttgca ctgttcgtcc ttggttctat tggttatagg cgaagagact tactagaagg
    63061 ataataaaaa agcatgtaca atttcatgct agcctccaaa tctgggtcaa aaatccaaca
    63121 tttggaggtc atttttttat ttacaagtct tctaactgct ctttatcaat gatccagact
    63181 tctcgattct ttctttttac ataaccattc tcctctaata atttaaattt tctagataaa
    63241 gtttcggggg tcgtaccgat aaatgcagca agttctttca ttttcattgg caggaaaaag
    63301 tgatccttcc ctgtcgcttt agctaagtca agcagataga gagcgactcg ttcttctact
    63361 ttttccatca tcaaaaaagt tgtctgctgc tgtacttttg ttaatttctc aacgttgatt
    63421 gctaaaagtt tcagactaag ggcgggataa tgcagtaaga gttccgagaa atctttttgt
    63481 ctcaatatgc aaatttccgt tttttctagt gcttcgccaa ataaagactc atttggaacg
    63541 cctagcaact ggctctctcc ctcatatccg cccggctcta ttactcgtaa aagctgttcc
    63601 tttccgctag cagataattg atacactttc atactgccgg aggccacgat cactaattga
    63661 ggttctccat tcggcgcaag aatctgttct cctttttcca catagtgatg tttgacaagt
    63721 gcgtgtactt tttcttgatc ttgctgtact aagtgattga acaaaggaac aaatgaaaca
    63781 cataaatgat catgactcat aatctctcct ccttctaaac agctatttct aataaagaaa
    63841 cataacttcc cttattccaa ctgataattt tcttttatca tagcataaac gtcaagcgaa
    63901 ccagatacca gcaaatagag tggatttctt tttgtccctt gctttatttt ccttcttttg
    63961 agaccttaag taattgattc ctatcaattt tttaaatatt tactttttga ataatcaaaa
    64021 acaaaccttc actcgcaagc cgagagtaag gtttgttttt cgcattgctt atttcgtgtt
    64081 gtctattgaa atttttccgc acctagcttt tgatatagtg gtgctagttc ttgtaaggtt
    64141 tcagcggtta tttgctcaac gtgttcgatt tcttgcggat agaagaatag tttacccatt
    64201 tgaaaggttc ggtctctcat cgcttttttc aactcttctt gtttctttgt atcggacaaa
    64261 tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg gttgcggcca tatgtaataa
    64321 tccttgatat cgactgtttt gctccactct ttcagtatcg caagcaactg gttatacgct
    64381 gcaatgctac catatcgttc ttcgctttta taatgttggt acatcaaata gatttggtat
    64441 tgtttttgat tcaacaaaac tgctagacag gcattctcgt cttgacgaga ttcgcttcgg
    64501 tacgcgctcc aaaaatgact gcgtaaattc cagccattcg tccagctttc gattttaggt
    64561 ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct ggagctgaat ctctttccat
    64621 ttttgccagt gttctttata ttctttcttg atttgttcaa tcttatctgt tggatggctc
    64681 tctttgagct gtttgaatgc gtagattggt cgatcaaaca actgataatc tgattttcca
    64741 agttccattg tttcgcctct ttccgttatc ttttgtattc tacctgaatt ttgcgatatg
    64801 gacaaataga ggttgtgaaa aagctgttct gcatcaagtc ataagaacag ccaaacaaaa
    64861 aactgcgatg agcatcaccg cagttttatg gctctataat ttatgggact gatgaatcag
    64921 aattgattct tcagccccat ttttatttta ggtattaaaa aacatatcgt tctctagtat
    64981 gattaaatca cgacaaaata aacaactgag aggacgatat gctatatgaa tgattctatc
    65041 aaaaaaatgc tgcgattaat agagaaagat ttgatgatta cagaggtctc ttacgagacc
    65101 tttcagaaga aaaagacgtt gatcgtcgat gctgttttct cacctgctcc cc
//
LOCUS       DAZAOD010000008        55610 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000008 DAZAOD010000000
VERSION     DAZAOD010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.008"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            246..566
                     /locus_tag="ACHDPO_000551"
     CDS             246..566
                     /locus_tag="ACHDPO_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFN3368212.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            720..1625
                     /locus_tag="ACHDPO_000552"
     CDS             720..1625
                     /locus_tag="ACHDPO_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368213.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1622..2395
                     /locus_tag="ACHDPO_000553"
     CDS             1622..2395
                     /locus_tag="ACHDPO_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFN3368214.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2576..4000)
                     /locus_tag="ACHDPO_000554"
     CDS             complement(2576..4000)
                     /locus_tag="ACHDPO_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFN3368215.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4211..4657
                     /gene="nrdI"
                     /locus_tag="ACHDPO_000555"
     CDS             4211..4657
                     /gene="nrdI"
                     /locus_tag="ACHDPO_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFN3368216.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4722..6704)
                     /locus_tag="ACHDPO_000556"
     CDS             complement(4722..6704)
                     /locus_tag="ACHDPO_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFN3368217.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6718..7614)
                     /gene="murQ"
                     /locus_tag="ACHDPO_000557"
     CDS             complement(6718..7614)
                     /gene="murQ"
                     /locus_tag="ACHDPO_000557"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFN3368218.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7617..8678)
                     /locus_tag="ACHDPO_000558"
     CDS             complement(7617..8678)
                     /locus_tag="ACHDPO_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFN3368219.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8889..9416)
                     /locus_tag="ACHDPO_000559"
     CDS             complement(8889..9416)
                     /locus_tag="ACHDPO_000559"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFN3368220.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(9483..10985)
                     /gene="eat(A)"
                     /locus_tag="ACHDPO_000560"
     CDS             complement(9483..10985)
                     /gene="eat(A)"
                     /locus_tag="ACHDPO_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFN3368221.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11243..12364)
                     /locus_tag="ACHDPO_000561"
     CDS             complement(11243..12364)
                     /locus_tag="ACHDPO_000561"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFN3368222.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12490..13431
                     /locus_tag="ACHDPO_000562"
     CDS             12490..13431
                     /locus_tag="ACHDPO_000562"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFN3368223.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13581..14477)
                     /locus_tag="ACHDPO_000563"
     CDS             complement(13581..14477)
                     /locus_tag="ACHDPO_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFN3368224.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14746..16086
                     /locus_tag="ACHDPO_000564"
     CDS             14746..16086
                     /locus_tag="ACHDPO_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFN3368225.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16304..16747
                     /locus_tag="ACHDPO_000565"
     CDS             16304..16747
                     /locus_tag="ACHDPO_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFN3368226.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17251..18669)
                     /gene="nhaC"
                     /locus_tag="ACHDPO_000566"
     CDS             complement(17251..18669)
                     /gene="nhaC"
                     /locus_tag="ACHDPO_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFN3368227.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19072..20295)
                     /locus_tag="ACHDPO_000567"
     CDS             complement(19072..20295)
                     /locus_tag="ACHDPO_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFN3368228.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20326..21165)
                     /locus_tag="ACHDPO_000568"
     CDS             complement(20326..21165)
                     /locus_tag="ACHDPO_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFN3368229.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21182..21862)
                     /locus_tag="ACHDPO_000569"
     CDS             complement(21182..21862)
                     /locus_tag="ACHDPO_000569"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFN3368230.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21864..22937)
                     /locus_tag="ACHDPO_000570"
     CDS             complement(21864..22937)
                     /locus_tag="ACHDPO_000570"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFN3368231.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(22993..23231)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(23274..23507)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23584..24255)
                     /locus_tag="ACHDPO_000571"
     CDS             complement(23584..24255)
                     /locus_tag="ACHDPO_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFN3368232.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24342..26990)
                     /gene="mgtA"
                     /locus_tag="ACHDPO_000572"
     CDS             complement(24342..26990)
                     /gene="mgtA"
                     /locus_tag="ACHDPO_000572"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFN3368233.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(27332..27506)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            27679..28116
                     /gene="ndk"
                     /locus_tag="ACHDPO_000573"
     CDS             27679..28116
                     /gene="ndk"
                     /locus_tag="ACHDPO_000573"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFN3368234.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28138..29004)
                     /locus_tag="ACHDPO_000574"
     CDS             complement(28138..29004)
                     /locus_tag="ACHDPO_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFN3368235.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29164..31257)
                     /locus_tag="ACHDPO_000575"
     CDS             complement(29164..31257)
                     /locus_tag="ACHDPO_000575"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFN3368236.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(32006..32629)
                     /locus_tag="ACHDPO_000576"
     CDS             complement(32006..32629)
                     /locus_tag="ACHDPO_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368237.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32788..34185)
                     /locus_tag="ACHDPO_000577"
     CDS             complement(32788..34185)
                     /locus_tag="ACHDPO_000577"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFN3368238.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34217..35188)
                     /locus_tag="ACHDPO_000578"
     CDS             complement(34217..35188)
                     /locus_tag="ACHDPO_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3368239.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35562..35987
                     /locus_tag="ACHDPO_000579"
     CDS             35562..35987
                     /locus_tag="ACHDPO_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368240.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(36475..37176)
                     /locus_tag="ACHDPO_000580"
     CDS             complement(36475..37176)
                     /locus_tag="ACHDPO_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFN3368241.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(37192..37632)
                     /locus_tag="ACHDPO_000581"
     CDS             complement(37192..37632)
                     /locus_tag="ACHDPO_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFN3368242.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(37632..38207)
                     /locus_tag="ACHDPO_000582"
     CDS             complement(37632..38207)
                     /locus_tag="ACHDPO_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFN3368243.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            38448..38657
                     /locus_tag="ACHDPO_000583"
     CDS             38448..38657
                     /locus_tag="ACHDPO_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFN3368244.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(39055..39567)
                     /locus_tag="ACHDPO_000584"
                     /pseudo
     CDS             complement(39055..39567)
                     /locus_tag="ACHDPO_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(39693..40394)
                     /locus_tag="ACHDPO_000585"
     CDS             complement(39693..40394)
                     /locus_tag="ACHDPO_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3368245.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(40502..41945)
                     /locus_tag="ACHDPO_000586"
                     /pseudo
     CDS             complement(40502..41945)
                     /locus_tag="ACHDPO_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(41959..43824)
                     /locus_tag="ACHDPO_000587"
     CDS             complement(41959..43824)
                     /locus_tag="ACHDPO_000587"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFN3368246.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(43945..44795)
                     /gene="licT"
                     /locus_tag="ACHDPO_000588"
                     /pseudo
     CDS             complement(43945..44795)
                     /gene="licT"
                     /locus_tag="ACHDPO_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            complement(45105..45818)
                     /locus_tag="ACHDPO_000589"
     CDS             complement(45105..45818)
                     /locus_tag="ACHDPO_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFN3368247.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(45886..46212)
                     /locus_tag="ACHDPO_000590"
     CDS             complement(45886..46212)
                     /locus_tag="ACHDPO_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFN3368248.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(46335..46562)
                     /locus_tag="ACHDPO_000591"
     CDS             complement(46335..46562)
                     /locus_tag="ACHDPO_000591"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFN3368249.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(46884..48137)
                     /locus_tag="ACHDPO_000592"
     CDS             complement(46884..48137)
                     /locus_tag="ACHDPO_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFN3368250.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            48198..48938
                     /locus_tag="ACHDPO_000593"
     CDS             48198..48938
                     /locus_tag="ACHDPO_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFN3368251.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(49024..49782)
                     /locus_tag="ACHDPO_000594"
     CDS             complement(49024..49782)
                     /locus_tag="ACHDPO_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFN3368252.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(49779..50243)
                     /locus_tag="ACHDPO_000595"
                     /pseudo
     CDS             complement(49779..50243)
                     /locus_tag="ACHDPO_000595"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            complement(50262..50759)
                     /locus_tag="ACHDPO_000596"
     CDS             complement(50262..50759)
                     /locus_tag="ACHDPO_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFN3368253.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            complement(50827..53994)
                     /locus_tag="ACHDPO_000597"
     CDS             complement(50827..53994)
                     /locus_tag="ACHDPO_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFN3368254.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(54218..55102)
                     /locus_tag="ACHDPO_000598"
     CDS             complement(54218..55102)
                     /locus_tag="ACHDPO_000598"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFN3368255.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(55197..>55610)
                     /locus_tag="ACHDPO_000599"
     CDS             complement(55197..>55610)
                     /locus_tag="ACHDPO_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368256.1"
                     /translation="LFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSVLVLGTLII
                     AGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFLCFYLPPKI
                     FTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
BASE COUNT        15970 a        11718 c         9587 g        18335 t
ORIGIN      
        1 aacttctttc tatgaaattg caaagcattc atcttctttt ccgctaacga tatatccgtc
       61 agtgcttggt acactttact aaaaagtatg agattgccga tatctggata ggtgtgctat
      121 actacagaaa aagatataca atctgccacc gggtaggata aagaggatga tcattccatt
      181 aggtctttga agggatgatt ttcctctttt tgtgtatttt tttatagtta aggaggaatg
      241 taagtatggc atggatggaa ttaatcatag caggaatttt ggaagtattc tggtcaacga
      301 tgatgaaatg gagtgatggt ttttctaaaa tcaattattc tttttacaca gtgattggca
      361 tgattgctag tttttacttt ttgtcaaagg caatcaaaag tttgccgatg agtctctctt
      421 atcctatctg gacagggatt ggcgcagttg gttcggtcat aattggtgtg gtcttgtttc
      481 atgataagct gaatctttcc acttggttct ttgtggggat gctactcatc agtatcattg
      541 gcatcaagat tactagcggc cactagacac ttggaataag tactgatcag aaaaaataag
      601 cctttttatt taatattcaa tttttttatg aaaaaataag aaataagtcc aatgacctag
      661 cgacttctcc actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt
      721 tgaaaagtct ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg
      781 atgtcagttt tagcttatcc cctggcaaaa tcgttggatt agtaggtcct aatggcgctg
      841 gaaaaacaac gatcatgaaa gctattttag gactgatcca ttactcagat ggaacaatct
      901 gtattggtga aaatgagatt tctccctcta gtcataaagg gttggaacaa gtaggagcat
      961 tgatcgaata cccgggtatc tatccattct taacaggcta tgatcatctg aagttattct
     1021 ctgaaaccaa cgatgtatct gctatcgaca ctatcgtgaa tcagctcaag atggaaaagt
     1081 acattcacaa aaaagcgaaa tcctactcgt tgggaatgaa acaaaaattg ggaattgctc
     1141 ttgccttact gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc
     1201 cacaagcaac aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt
     1261 tcttgatctc cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga
     1321 tcaatcaagg aaagatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag
     1381 atttcatcgt tatctctaca acaaatgatc tagctgctcg aacgatcttg acagaagctg
     1441 gatatacttt ggaagatcct gataaaatca agcttttaaa agaaaacgaa gaattattag
     1501 gaaccgtgat ccagctattg tctgcacaaa atatccatgt gacagacgtc cagcatctga
     1561 cgaatgattt ggaatcttct ctattggaaa ttctggattc agtaaagggg gaagaagaaa
     1621 aatgacattg cttgtaaaac aagaattatt taaattgatc aagaaaaagt caactgctgt
     1681 tttatctgtt ctattagttg ttttgctcat aggaacagca cttctagcca aaaaatacac
     1741 gacgatcatt gatccagttg aaatgactgc tcagcttttt agtgccacat cttggattgt
     1801 ctttatcatg attgcagctg caagcacgat catttcgatg gaagcacaat atggtacatt
     1861 gaaaaatctc ctttatcgaa agtattctcg aggagaaata ttagtaagca aatggatcac
     1921 attagttatt tattctgttt atttatacct tttagctatt attgtcactg tgttgatgaa
     1981 actgattctt ttcccttcga tttccttcac ggagaaggtt tctactggtc aaacactgat
     2041 ccaaagcttg ttcacttata ctttgggtag ttatatcggt ttatggctga ttttaagttt
     2101 agtgttgatg attgcttgct ttatcaatag ttccggcgca tccatctcag caggaatcgt
     2161 cttttatttt gcttcgtcaa tcatatctgg tatccttatt gcactcatcc aaaaatggga
     2221 gtggatcaaa tggaatccga tcagtatgtt gaatctgcaa aaccaaattg gaaacgaaga
     2281 gatcatgaag caattgactc atctttctac taatcaaatg ctattcggta atttagctta
     2341 catcgttttg ttcttagcat taggatatct cgtatttaag cgaaaaaatg tatgatgact
     2401 catcaaaaaa gaggctgtga aagagacgtt cagccttatt gccgattggc tgtctcttaa
     2461 acaccgttta ttctgaaaaa ggagctgtga caacatttgt gtcacagctc ctttcctagt
     2521 atgtttttga ataaacgaca ggctcacaac ctctctttat acttctttta tacttctata
     2581 cgtgaagcat cccagtggca aataaaacca ttgcaatcac tccgaccatc gtcacaccta
     2641 taagtaaaat cttatctaag tggatatgtt gtacaggctc gttttgctcc ttacgtgctt
     2701 tgaggtaaaa ataaatgcct ggcaagaaaa gaacaagaac aagcattact tcattaaagg
     2761 ctacgactag catagcccat acttgaaagg cacttgctaa aagccctact aaaaattgga
     2821 cccattcttt ccgctgataa gaaagtttca tttggtacaa tcctaagaaa agccacgtga
     2881 agaaaatagc tgctgtacca agtgtgtaag caaagttata agcactgtca gtgaataata
     2941 atgaaagtaa aaagacattc gtacataacg tcgtcaatac gatagcataa gttggtgccc
     3001 catttttgtt gagttttccc catgctttag gcaaaagtcc gtcttcagcc atgtttccca
     3061 ttgtttcaat cggtaagatc gtccatgaga gccaaacacc aactaaagaa atgatcaaac
     3121 cgccgttgat cacgactgct ccccatttac caaccatcat ttcaaacaca tagcccatag
     3181 caggctgcgc cttgatcgtt tgcagctgat tcatcgtcat tgtcccatat ggaagcatgg
     3241 aaaccaagac gtaaataata atcaagccga atatccctag aatcgttgct ttcccaacat
     3301 ctgattgttt ttttgctcgt gaacctacga cagaggctcc ttcaatacca acaaataccc
     3361 aaagcatcac catgatgcaa ctcaatactt gactggaaaa cgggatcggc tgtccattcg
     3421 cattcaatat aatgtcgcta gaaaagttat caatgaattg ttggatcgaa aacgtgctga
     3481 tagctactac aataaataaa aataatggca ctaatttaca gaatgtgacg atagcattga
     3541 cgaaactagc attttcgact ccccgattca ctagccatgc atatccccat aaaaagactg
     3601 tactcatcac gatcgatgcc agattttgcc caccttcaaa tactgggaag aaatatccta
     3661 atgcgctcat caacaatgtt gcaaaagcta cgttgcctaa ccagcatgtg agccagtaac
     3721 cccaaccgct gataaaacca gcgaaacggc caaaaccttc ttctgcgtaa ctaaagatcc
     3781 cgccttttaa atctggacgt tttttattga tattattgat cgacaaggag agcatcaaca
     3841 ttgctgttcc tacgagtacc caactgaaaa tagctgggcc gccagccgat ccggagatgt
     3901 ccgtcataat accaaatacg ccacctccaa tcgctgaacc aattactaag gcagcaagtg
     3961 gaattaaacc aattcctttt ttctgttgct ctgtatccat gtaagcatcc tccaaaataa
     4021 aaccgctttt atcaaaaagt ataacaaacc ttttttattt ttacttaatt aataaaaact
     4081 ttaatagaaa tataattcta ccggcttttt tctcattata caagcaaagc gcctagtccc
     4141 tttccaaatt acaccaccaa aaaacttaaa aaagatgcta tactaaaagg aaagaattgg
     4201 aggatgatcc atgaacattt tatatatatc gatttcagga aatacgcgtg cctttgccaa
     4261 acatctagca gaatatgctg aaaaaatgca tgcagaagat cctgtcaatc ctgaagttac
     4321 tttaaaagaa atccatgaaa atagtgattt tacgaaagaa acagaaccat tttttacttt
     4381 cgttcctact tatttagacg gcggaaatgg tttagataac ggtgatacag aaatcttgac
     4441 cgaaacgatg cgtgaatatc tggaacatga agacaatcat aaactttgtc ttggtgtagt
     4501 cggtagcgga aataaaaact tcaataatca gtattgtcta acagccaaac aatatgcaca
     4561 aacatttggc tttcctttct tggcagatta tgaattacgg ggaacaccat ctgatgtgac
     4621 acgaatttat cagattttag cagaaaacaa taaataataa aaaagaagaa gctgaaaaat
     4681 agatttcagt ttcttctttc gtttctattg tttctatcat attaagcttt gacatccatc
     4741 acaggtgctt ttgcttttgc tttacctgtt ttttccaaga caaagttttt tacacgatcc
     4801 atattggtta ccaagacgat catggatgtt tctttgcctg ctgctttgat cgcttctaag
     4861 tcagcttctg ctacaagcgt atcaggtgtc acttgctgcc cttctgttac tttcacatca
     4921 aatggcgtac cgcctaagtc aactgtgttg attcccatat gaagcaagat ttctaaacca
     4981 tttggcgttg tgatcccaat agcgtgtttc gttgggaaga cagagctgac taccccagta
     5041 actggagaat agatatgtcc gttttctggt tctacaaagt agccttcacc catcatcttt
     5101 tgtgcaaaaa ctggatcact tgctttatct aaagaaacaa ctgttccgtc agcaactgat
     5161 gagaggatag tcacactttc agctgaagtt tgaggtacta ctttttcagg cacttcattt
     5221 actgtggctg tttcagtcgc taattcttct ttttctaaac ggtctttagg aataccgaag
     5281 aagaatgtag caacgaagcc accagcataa gctgccaata atccaaggat gtagcctaac
     5341 catttaccgt cagagatcaa tgggatcaaa gcggctcctg aaggtccaat agcgatagcc
     5401 ccgacatttc cgatcattcc gatcactgcc ccgccgatac ctccaccgat acaagcagta
     5461 ataaatgggc gtcctagagg taatgttact ccgtaaatca atggttcgcc gattcctagg
     5521 atcccgactg gtaaagctcc tttgatcatt tctgttaatt ctttatcttt tttgcagcga
     5581 atccataatg ccaatgctgc acccacttgt cctgcaccag ccatcgcaag aattggaagc
     5641 aatagcgtac gaccagtttc atcaatcatt tgcacatgga ttggagtcaa aatttgatgc
     5701 agtccgaaca taaccatcgg caagaataat gtgcctagaa cgaagccggc aaatgctcca
     5761 ccaacgccaa gtacccagtt gatcccaccg accatgccat cagaaatgaa acctgctaaa
     5821 ggcatgatga agaaaatttc aatcagaccg atggcaatca atgaaagagt tggtgtaacg
     5881 atgatatcta ccgcatcagg tactacttta tgcagttttt tctcaacgat tgacaatagc
     5941 caaacagcga agatgacacc taggatccca ccttgtccag ctgcaagagc ttcaccagta
     6001 aataagtttt tcagtggtgc ttccggattc atccctgtca gcatcacaac ggccccgata
     6061 actccaccaa gagttggtgt tgcaccaaaa acttgtgcag cattgatacc tgtatagata
     6121 actaggtagc taaacatccc gtttttcaag atgttcatca catcgatata ttgttgccat
     6181 gttgctgcat caagtgttcc ggctgtgact aagtttgcta aaactgcggc aatccctgcc
     6241 acgatcccag taccgacaaa tgcaggaatc attggcacaa agatattaga aatgtctttt
     6301 aataccgatt tgattttaga tggtttttgt ttcgattttt gtgccgcttt catttcttgt
     6361 gcccgttcgt ttacacggtc ttttccagat gctgatgaat ttgctgtagc tgtacttaca
     6421 gaagaaagtt tttctcctaa tttcacgcct gccaaatcaa ccatttgctg tgctactttg
     6481 ttcactttcc caggtccgat gatgacttga agctgttcat cttctactac accaagcact
     6541 cctggaatcg cttttaattc agagacattt acaagatcat cattgatgat cttcatacgc
     6601 acacgagtca tgcagtggac aatgctttct acattgccca tgccgcctgc ccctttataa
     6661 atttgttttg ccagttcttc caaagtcagt tcgttttttg ccatggtctt ttccccctca
     6721 taaggtccct tttacaaatc cgtttgcttc agctaatttt gcttgagctt cctctttatc
     6781 actatttgtc aaaatcatga cgatagccag cttaacattt tgatctgctt cttcaaagta
     6841 cttttcagct gtttcgtaat cagcttctgt cgcttgcatg atgattcgtt ttgagcgttc
     6901 gattagtttt tcatttgttg gtttgacatc gaccatcaag ttattgaata ctttacctat
     6961 accaatcata ctgatagtag aaatcatatt caagataagt ttttgtgctg ttcctgactt
     7021 caatcgagta gagcctgtca aaaattctgg acctgcatcg acttcgattg ggaaatccgc
     7081 gtgtttactg atttcggctt gtttattgca agaaatcgtt cctgtgacag caccgatcga
     7141 ttttgcgtaa tctaatccac cgatcacata tggtgtacga ccgctagctg cgataccaat
     7201 aactatatca ttttttgtca aattcagctt gattagatct tcttgcccta gctcataaga
     7261 atcttcggcc ccttcgacag ctacagtcat tgcttcttct ccaccagcaa ttagacctat
     7321 gaccatttcc ggttctacac cgaatgtcgg tacgcattca gcagcatcta acacacctag
     7381 tcttccactt gttccggctc ccatataaat cagacgtcca ccttttttaa aggactcaat
     7441 cgtgttagca atcactggtt cgatacttgt cagttctttt tcaaccgcag cggccacttt
     7501 ctgatcttct ttgttcatta gttgaacggc ttgagaaata ctcatctcat ctaatccaaa
     7561 agtttcttgg tttctgcgtt ccgttgttag gttctctaaa ttgattttgc tcatttttat
     7621 cttccttctt ttcttataaa ttgatagttc ataccagctt tgatttggtt gatcaatggt
     7681 agctcttctt tgataacttt agctactaca ttcacttttt catccgctgg caaatcatat
     7741 ttggttaatt ggatctcacc catatagcgc aaatactttt cgttatctaa agtaatagac
     7801 cctttcatac gcgtagctgt atttcttgct gggataggcg gaatctctcg aaaacgtgca
     7861 tctacgcttc gtatgacatc tcttgcatcg tcttgccgat tcgtatgctt ccctaatata
     7921 tattcgtaaa attcttcatc tacaggttcc gtatggagca agactgtctg ttctttttgg
     7981 aaagaagcaa attgctcctg aacgttttct gacagacctg catctccgat gtaaacaata
     8041 tccgtgttac ttgctaatag atctagagcg cctgcaagag gatggatccc tcgatgttct
     8101 tccaaagttg gcaatccttg atatagtggg cctctcaact ctgtatctcc tggtacaaaa
     8161 ccttggacaa ggagaccttg aattttgagc cattgatttt ttttctgata ccattctttg
     8221 tccagccctg tttcgggacg tggataataa ttatgccaag cttcaatctg tgagaaatca
     8281 gcttctgctt ctttcaattc atcgatatct ttaggcgtga tcgtgctagc attcaaactg
     8341 attttcaatt gatgtgacca gtcggcaatc tgctgattgg aaatatgata atccattctt
     8401 aaacctgtta caccaattgc tttcaaaggc gttagatctt ctaatgaaaa acccgctcgt
     8461 tccaatgcct ctcctgaaat atcgaccatc aattctagtt tattcttttt cgcttcgctt
     8521 cctagttcga tcaatcgctt ttgatatgcc gaaacatcat cttctggtat atgcatggaa
     8581 gtgaaaatac cgacaaagcc attggatgcc atttggcgga tatactgttt cttctcttct
     8641 gacaaagaat cgttcataaa tattgaaaag ccaaacatat tatccctctt tttctgtatc
     8701 cgtcttcatt tctatgacta gagtatatat ctaaagaaac aaaatttcaa tacttttatt
     8761 aaaataatta aatttcattt ctaaaggttg agtttatatt atcaaaagaa ttgtcataac
     8821 ctaaaaaagg cactgctaag caaaagcagt gccttgaaat attttattta aataacacaa
     8881 aaacataatt actcataaga aaccaattct gtattatcta ccatgaatgt aaagaacccc
     8941 tcattaggca tcggatgaaa ataagcattg atcactctta tcaaggcatt atggcaaact
     9001 aacagataga cattttcttc gtcttcgatg cattctttca ataaaggaac gatccgtgca
     9061 tacacatcta agactgactc cccatttggg aatcgtacag cgaacgctaa acgtgctttt
     9121 tgaaagttct catctttgct tggcagtcca tcataatccc caaaatccat ttctaccaat
     9181 cgttcatcaa cggtcagcgg caagctgaga cgatcagcaa ctgcttgtgc tgtatctctt
     9241 gctcgttgaa gaggggaatg gatgattttc gtgattggaa caggcaaatc tactaccttt
     9301 tctgctagtt tctgtgcctg catctgtcct ttttcagtca gcggcacatc tgcccgtccg
     9361 caaactaatc cttgtgcgtt ccaagttgtt tctccgtgtc tcgttacata aagcatgtga
     9421 ttctctcctt cgttggcaaa gttcccctta accatacctt gttgttcttg agattacaag
     9481 ggttagattc tctcaagaga aataatctca gtagatactt tatccaggaa ggtttgatca
     9541 tgttccacta gtaacatggc aggtttcacg ttcaagatca gttgttctaa ttgttcttga
     9601 ttgaagacat ccaaataatt caatggttca tcccatgtat atagttcagc tggctgtgat
     9661 aaagatttag ccaattccac ttttttccgt tggcccatac tcatctgctc gatcttgtta
     9721 tgaaaaacat ctctttccat cccaagcttt cggaggttgt tcaaaaatgc ttggtagtct
     9781 acttggtttt tctctgcaaa ttccgccaac gttcctcgat tgtcttcata attttggctt
     9841 gcataactaa tgctcagatg ttttggctgg tatttttctc ctataacctt gccgttgaat
     9901 gcccccagaa gataatggat aatggatgac tttcctgcac cgttaggacc tgaaatcgcc
     9961 acccgctgat gaggctcgat tgtaaaatga attggctcga ataacagatt ttcataccct
    10021 aattgaagat cttctacgct taaaagtcgc ttatggtgag acgcttggct attcatcgtc
    10081 aaagaatcga tatattcgat atcttttaat agtttttctt tctcgctgat ctgggtctcc
    10141 atccgattca cgattgcttt ggatcgtttc atcgtccgtg cagcatcagc acccactgct
    10201 cctttattca ctcgtctaga ttcagtatcg atgaatccga cttgtttctt tgttttatct
    10261 ccttctcggg aacgagacca ttcggctttt tcagctgctg ttttctttag cctactgact
    10321 tcttttttca atttttcatt ttgagccatt tcaaattcat cacgaagttt tttctgttct
    10381 tcatagatag agaaattccc ttgataaagt tccagttgac ttttttcgat tgctaaaaca
    10441 tggtccacta cttcatcgat aaatccccgg tcatggctga ccacgatgaa gccttgtttt
    10501 ttctttttca aataagccgc tacttgtttt ctaccagaga tatccaaatg attcgttggt
    10561 tcatcgatta acgggaaatg agtgtcatcc acaaataaaa gtgccagtag gacttttgtc
    10621 ttctctcccc ccgatagtgt gctgaattct ctccataaga tttcaggatc tgtttgcatc
    10681 aattggagct ctctttcgat ttcccatatc tcaaaatccg taatatcatt taacacgtaa
    10741 taggttaaac gttctttatc ttttgtctgt tgcgggaaat aggcaaattc ttgctgatgg
    10801 attacttgcc cttgataagg tagtttgttt tgtagaatat tcagtaaagt tgtctttcct
    10861 cgaccgtttc gtccgataag tcctagtttc cattgtgtgt caaaatttag atttgcttgt
    10921 tcaaataata atgtgccttg gctgtcgtag ccgaatgtca gattttttat ttcgatttta
    10981 gacattttcc atcacctcgt aaaaaaagac cagtcctatt ttcagaactg gctaaagagg
    11041 atgcaagggt tggatacaca caaaaagacc catacatcga aaaaaccaag ccaatcccga
    11101 aaatctgcac actgcttcct tgtctccaca aggtacagtc tgaatgcagc tttcatcaat
    11161 cgacttaatt tttcaatgca cggatccctc actttgtcct atatttgaaa ttacgatagc
    11221 ataaagaaaa tgattttgtc aactacttcg ggaggatggt gaaaaatctg ctaagtgtct
    11281 gtcctaagat ttttgttttt tctaatgttt gcctgtgttc cattgcttct tctaaaccta
    11341 ttggacccaa atgaatactt aagacaattg ggagaaaatc agaaagtcct tctagctctt
    11401 ggtctctact tccgcaaata gcgattattg gttttcgata tttttttgca agcactgcta
    11461 caccgtatgg aacttttccg tggatcgttt gctgatcgat ccgcccttct cctgtaatga
    11521 tgacatctgc ttgttcgatc tttttttcca atccagtgat ttggctgact aaatcgaaac
    11581 cagaaaccat cttcgctccc aacaaaaaaa gggctccacc aataccgcct gctgctccac
    11641 ttcctggaat atcatctaaa tccacctccc agaaatcttt tatttgctga gcaatctttc
    11701 ctgcttgttt atctaagaaa gctagcgtcg tatctattcc tcctttttgt cttccaaatt
    11761 gccaagcagc tccttgttga cctgtatatg gattggtaac atctgcagcg ataatcaatt
    11821 ttactttaga aacaagaacg tttcttcgat caaaatgaag ttttttagta gataataaag
    11881 gatttccttc tgtgtaccct tctaaagaag cacccaagga ttggagtaat cctagaccac
    11941 catcgctaca cccgcttcct cctaaagtga caataatttg ttctacttct tgaagcagtg
    12001 catctttaat aagttctcct aaggcataac tggaagcaag tcggatagtt tgatccgttg
    12061 gtttatcaag tagatctaac cccaatgctt gtgcagattc gatgactgcg gtgttttttc
    12121 cttgccaagt tgtcaataaa tagctgattt ttcgctgacg gaataagaga tccatcccat
    12181 caatggtacg ccatgttccc ctgagcgcgt aatagattgc ttctgcagta ttttctccgc
    12241 catctgcaat cggcacattg atttttcttc ctttacgatc ttcccagcca tttagaactg
    12301 cctgatttag ttcaaatgaa gaagcacttc ctttaaatga atcaattgcc gccaaaatat
    12361 ccatctgtat ccctcacttt cttcttaagt aagacacttt ttttcatttt tttcaaacaa
    12421 aacaatgcta ttttcttcca tttttctata tactaaaagg gaactcattg aataaaggag
    12481 agaaaaaaca tgaaaatcgc aatagctggg gccggagcaa tgggcagccg aatcggattg
    12541 atgctacatc aaagcggaaa tgaggtcctc ttgatcgatc gttggcctgc tcacattgaa
    12601 gccattcgta caaatgggtt gattgctgac tttaacggta aagaagtggt cgcaaaactg
    12661 ccaatctatt caccagaaga aatcatcgaa agcaacgaac acgtggactt gatcgtagca
    12721 ttaacaaaag ccaatcaatt agatgatatg ttttgttcga tccaatccat tattactgac
    12781 aatacttatg ttttgtgttt actaaatgga ttaggtcatg aagatgtact ggaaaaatat
    12841 gtgccaaaga aaaatatctt atttgggatc acgatgtgga cagctggtct agctggtccc
    12901 ggaaaagtca cattgttagg tgatggagaa atcgaactag agaacttgga accagaaggc
    12961 gaagcattta caaaaaaagt tgtagaagtc tttcaagaag caaatttaaa tccgatctat
    13021 agccataacg ttcgttattc catttggcga aaagcttgtg taaatggaac attgaatggt
    13081 ttatgcacga ttttggattg taatattgct gaactaggcg cgcaaaaagc ggcagagagc
    13141 atggttcgaa caatcgtatc tgaatttgct tctatcgcag caaaagaagg aatcatacta
    13201 gatcaagaag aagtgtacca acatattgct tctacttatg atcctgacaa catcgggttg
    13261 cattacccat ctatgtacca agacctgatc aaaaaccatc gtttgactga aatcgactac
    13321 atcaatggtg ccatttggcg aaaaggacaa aaatatgata ttgctacacc atattgtgcc
    13381 tttttgaccc aattagtcca tgcaaaagaa ggaatccttg gcgcagaata aaaggctctc
    13441 tgatgagaat cagctgaatc agcagctggt tctctttttt taagcccaat aaaagatcaa
    13501 aaagaaaaca caactctcat gatgccataa gaattgtgct tgtttgtttc agtacataat
    13561 ctcttcaaaa tgtaggtttt ttatttgttt tcaacagagg agaggtcata ttcgtattgc
    13621 tcataaatag tggaatcgtt agtgataaat cgttttgccc aattttctgc atcataaaat
    13681 tccaatagct ctgataggat tggcttaaat ggtgtatgca gaaattccgg taattcatct
    13741 aaatcacgtt ctcgaagcaa aaaaatattt tcaggacgat aaaaatgata atgagcaatc
    13801 gcttgattat ccgtcactag tttcttttga aaatacatgg attcaaatgt ccgcaaagtc
    13861 actccttgct gaccctcccg caacagttcc agaatcccgc gcgattcccc tgtttttttc
    13921 aggtactctt cataagtaag atatccaggt tgttcattcc ctcgatgtgg aagaatgaaa
    13981 tagttggtcg taacatctct ttttataaat tcctgcttat agctttctgc tcgttctttt
    14041 ctcccattat tcgttgcacc aaaaaataga tccgtctttg gttcgctaga agaaaaattc
    14101 atatgtttcg aataaaatga actattatgt ttcagcccaa gttcttttgc ttccaaaaaa
    14161 tcaaaatgat aaatctcatc gattgccggt tcatcttgtg cctgcttcag catcgcctcg
    14221 tgttctgctt tgaagtgatt ccaaaaaaat aacacaattt ttgcattggt aaatgggcgc
    14281 acgcgtcgag ccatctccat atcaaatcca taatctaaaa aaacgatcag ctgataattt
    14341 gccaactgtt gtctagctga tttaatgaat tccgactgta gtaaatcttt tccggaccaa
    14401 acatctaaag agcggatgga aggcaaaaaa taaagtgatt tattttttgc aactagcagt
    14461 acgtcatttt tgttcatctt ttccgcctca ctttctctgt cactttttcc tatgatagcc
    14521 tgtttaaata gtaaaaagcc agtaaaacgt ttcctatatt tgtatgaaaa tttaacattt
    14581 gtatgaaaat atgatgaaat aaatcattct tctattaaaa ttcgcctaaa agttttctga
    14641 atagttgtaa ttgtctgaaa atttgttatc attagtcatt gttaaatatt gctatttatt
    14701 cttaatataa attttgattg tgaatttaaa agaaagaggt catttatgga agataaaaaa
    14761 ttgaaaaaac aacttagctc cagacatatc accatgttag ctttaggtgg agcaatcggt
    14821 gcaggtctat ttaaaggaag tggcgaagcg attgggatcg ccggcccttc tgtattgatt
    14881 gcttttttga ttggtgggct gattttatat atcgtgatga aaggtctggg aaaaatcgtt
    14941 ttaagcggtg gcgacacgca tcacggatta tctggtttga tacgccctta tctaggtgct
    15001 cattctgctg attttactga ttgggtctac tggtctatgt ggattatcaa tatcatcgct
    15061 gaagctgttg cagctgcttc ctttttgcag ttgtggttcc cgcacattcc agcctgggta
    15121 tttgttttta tgttggctgt tttaactacg atcatcaatc tttattcggt acggttattc
    15181 gcagaaacag aatattggct ggcttttgct aaaatcagtg tcattatctt actgatcatt
    15241 tttgctactt atcttgtcgg tcagcaaatg ttgggcacag gcgttttccc tacccttcag
    15301 caattgactg accatggtgg gtttactcct catggtatga agggaatcat cagttctttg
    15361 cttgtagtta tctattctta cggcggttct gaactgattg ctatcacggt aagcgaagca
    15421 gatgatccta aacgtgcgat tcctaaagca atcaaaggtg tcatgggaag aatcatttcc
    15481 ttttacatca ttcctttgtt tttgcttttg attctttttc cttggaatac tttagcaggc
    15541 acgaatgtca gtccttttgt gatggtattt gaaaaaatga atatcccatt tgcagcggat
    15601 atcgtcaatt ttgtgattgt ccttgctttg ttctcatcta tcaattcggg tgtgtatgca
    15661 tcttcaagaa ttttgttctt ccgtttgaag gatcgaaaag gttcctctag aaaactagct
    15721 gttttaaaca agcatcaagt accgcaacgt gctgttttat tttgtaccag tgttctttat
    15781 cttggtgtag ctctttctta ttttgtcggt gacaaattat ttggctatct ggcaggttcc
    15841 ctttcgtata cagtattatt gatctggatc attatcagtg cggcatcctt tgtactggca
    15901 ctaagaaaag gaacattatg ggataaagga atcagctttt ttgcattagc tgtcttagga
    15961 ttgattttcc ttggtatcct gttcacgaac tccattgggg taactgtatt gactggcctg
    16021 ctttacctgt tcatttattt cagttatcaa aaaaagaatg atgcgttcgt attgacgaat
    16081 gaatgaaatc gatagaaaat tttattttat ttatgtggaa tagatggagc tattgaagaa
    16141 aggagttgtg acaaaagtct tgttgcaact cctttttccg aataaacagt ctcatgacct
    16201 cttggtaaac ggtgttcaaa aaccctctgt gcaaaataat tgattgttct ccatgctcat
    16261 gacatgatag aagaaaggaa tgaaaaaaag gagtttgttt taaatgaaaa agtattggaa
    16321 gtttttgttg atgatcggtg tttcaacggt agttatgttt ggtatgatgt acttgaatgt
    16381 ctatgcgctc gatcatatct tcttcagtcg tacacgagta ttcatggcgt tgatgatggg
    16441 tgcagtcatg gcagtcatca tgctgttgtt catgtggaaa atgtatgaaa acaaaaagat
    16501 aaatgttatg atcttagccg ctagtcttct tgtttttgcc ggttccttgt ttatggtacg
    16561 aagccaaact actgtcaacg acacagcttg gatgaaggcc atgattcctc atcattctat
    16621 cgctatcctg gcaagtaaac gagctgattt aaaagatcct gaagtaaaaa aattagcgga
    16681 agaaatcatt caggcacaag aagaagagat cgacaaaatg aaaaaaatga tcaaagaaat
    16741 ggaatgacca ttatccgtcc aaataaaaaa agaggatgtt ccagaagtta tcagcttcaa
    16801 gaaataagaa gaagctactt ctggaacgcc gtgaataagg ggttgtgaaa aagctgccct
    16861 gcatcaagta ataagaacag ccaaacaaaa atagcttctc ctatttttcg tttggttagg
    16921 cttattaccg cagatgcaag cttttgaaca ccgtttatta agaggttgta aaatcagcgt
    16981 tctgacctga gtattagaga gacaaatgga aaaatagttc ctcatatttt gccatttttt
    17041 gagctaatac cgagggtcag ctgattgaac accgtttatc gagaggttgt gaaaaagtcg
    17101 cttagtttcg cgtattaaga aaaattttgt gaaatggctt tccacatttt tgtataaatt
    17161 tggcttaata ccgagaaact ggcttttgaa taccgtttat tcgtaaaagg gattgtgaca
    17221 aaagtcttgt cacaatccct ttttatgttt ttattgttct aattgcgctg tcttgcttac
    17281 tgcttcttgc ggtttcacaa atttttttga gattccccaa cctgtgaagg cactgaccat
    17341 cgaaaacaca ggagaaagca aactgaaaaa tacgaatggc aagtaagtga gtgtaggaat
    17401 accaaatgta cttgctacga aacttccggc aattccccaa ggcactaagt agttgattac
    17461 tgttccacca tcttctagcg ttctacctaa tacagttgga tcaaatcctg ctttttcata
    17521 agtttcttta aatgcattac caggcagaat aacagatagg aattgttcac caataaaaat
    17581 atttactccg atacttgtca tcaatgttgt aaaaatcaaa tttggtgtgt tcgtcatctt
    17641 tcttgatact cgttccatca cggttgagat caagccaaat tcgatcaaca atccacctaa
    17701 tgacaaagtt agaataatca atgacacagt aggcatcata ctttcgattc ctccgcggct
    17761 aagcagtgaa tcgatttgtt ggtttccagt atttgaaaca aaccctgatt cgatgacccc
    17821 agccaacttc gttaaggaag tttgtgggtt ttgaataaaa atcattccta ctgctacagc
    17881 gatattcaac aaaatcgtta aaattgccgg cacctttttc catgcacaca gtaacattaa
    17941 aaataaagga atcagtgacc agattgaaat agtaaagttt gcttctagaa catcagtcac
    18001 ttcacgaata gatgaaagac ttgcggcttt acttgtgtgt cctaaaatca tgaataaaaa
    18061 gaaagaaaca acaaatgccg ggacagttga ccacatcata tgcttgatgt gtttgaacaa
    18121 atcggcatca acaatagctg ctgctagatt tgttgattcg gataatggag acatcttatc
    18181 tccaaaaacg gcacctgaaa caatagctcc aacaaccagc gctggattta agcctagtgt
    18241 tgtcccaata ccgaaaaatg caatcccaat cgttgacata acagtaaagg cactccctac
    18301 agcgctacct acgattgcac acacaacaaa tacagaaggg acaaaccact ggacactgat
    18361 caatttgaac ccaatgacca ttagagttgg aatgatccct gcttgtatcc atacagcaat
    18421 caatgaaccg actaaaataa aaataaagat tgggatgatt cctggtttga tgccattgat
    18481 gattccttcg tgcagccaat ctgtcgggta tctttttatc actgcataca acatgaccat
    18541 tccgatcgct gctaagatcg tgatattagg tgagaccttt aatccgacaa cgccaatcgc
    18601 aatgcctaaa acaataacca ttaatacaag tgttgcttct aaaaaacttg gtgttccttt
    18661 ttttcccatg ataatctctc cttttttagt tgttcttatg ttctaaaaaa gttaagatat
    18721 cggattactc cgccgcaatt catccgcgat tcctccttta taaaaataaa aagacctgtt
    18781 ttaaactaag gacgaatgac tccgcggtac caccttaatt aaaaacagat ctgtttttca
    18841 ctttcaaact tttattcaaa tgtatggact ttccatgtaa ttcgtcaatt aggcttgatc
    18901 ggttcacagc gaccaccgac tttctgaaca aaacacctaa ccgctactgc gtgaaaagtt
    18961 gacttgtacg aagtttacct tccataagat catttgtcaa tgaaaaagaa aatatttttt
    19021 catttttctg aaaattattt ttataacttt cacacacaag tttatttttt actagaaagt
    19081 agcgccctct tgtttttttc ttgctactat ttcttgatgt tcttgcttga ttctttctaa
    19141 tagctttggc tctttcaaca gatcaagagc tgtattggcg agtagttctg ctgcaatcgc
    19201 aatagaagca aggcctttgt cacttttagc agcagctttg aattcttctg tgtgtccggc
    19261 aatatatgtc tcagagattg ctaccgtagg ctggattgtt ggtatgactt ggctgacatt
    19321 tcctacatca gaagaaccga gacttgttct ttgttccgtt tctatttctt catctggaac
    19381 acctgcttct tttgcatgct ggaagaataa gtcatcaaaa gaaggagtaa cgatgacatc
    19441 atcaactgca ttttggaaca atccaaactc aaaagtcgtg cccgtactta tcgcagcacc
    19501 tcgtacgata ttttccactt tttcatatac tttatctaat gtttgccgat ttcctgcacg
    19561 taaatagaaa cgtccagcag cgtaatctgg aatgacgttg gcagctactc ctccgtctgt
    19621 aatgatccca tggatattga catcttttgg caattgcaag cgtagagcgt tgattccatt
    19681 aaacacttgg atcaatgctt ccaaagcatt tactcctttt tcaggtgctg ctgctgcatg
    19741 ggaagcgaca ccgtaaaatt tgatgtcgac tggatcattc gctaaagatt ctgtcgtttt
    19801 cccataacga aaagctggat ggacgcataa cgctacatcg acatcctcaa aaaaaccttc
    19861 tcgaacaaag ctgcctttag ctgatccgtt ctcgccccct tcttcccctg gggtgccata
    19921 tacacggatt tctccaccag tttcatcaat gaattgcttc actatgctgg cggctaatac
    19981 ggagtaagta ccaaacaaat tatgcccgca tgcatgacca atacctggta aagcatcgaa
    20041 ttctgccaaa aaggcaattg tgggaccggg tttattggaa atataacgtg catcaaaggc
    20101 tgttcggtgt ccagctactt ctttttctac ccaaaacctt tctttttcta attgtttaat
    20161 caacgctgct gaggaataaa actcatagtt acttacttca ggatgttcgt ggatatctag
    20221 agcaagtgct tgatattctg gtaaacgata ttggattaga tccttcaatt ggtttgttga
    20281 gattgttgtt gtcataaaaa attcctccta tgctagtcat ttttcttatt ttctcccgaa
    20341 tgtttcccat gcaggcacgc ttgatccttt tgatgttttc tcgattactt tgactgtgtc
    20401 ttctgtttga taagcgtcta ctattttttg atacgtttta ttgttttcat cttcttttct
    20461 tgcaacgatg atattcacat aaggacgtgc atggtcatcc actggttcta agaagatggc
    20521 atcagaagca ggattaaatc cagcatctac agctacaccg ctattgatca ctgaaatgtc
    20581 tacatctgac aaagcacgtg ctgtttggga agcatctaat tcagaaatgt ctagattttt
    20641 tctattctcg gtaatatcag aaacagtggg cgcttgtcct tttgccttat ccactttgat
    20701 caatccagca gtttgcaata acagaagagc tctgccgcca tttgtaacat cattagggat
    20761 tgctactttt gctccgtctt tgatatcagc tacatccttc aaagtgttag aataaattcc
    20821 cagcggtgca ttgacagtat ttccgatcga tactaaatca gttccgtgtt ctttattgta
    20881 attgtctaaa aagaattgat gttggaaaga attcaaatca atcgatccat ctgctaaagc
    20941 cacatttggt tgattgtaat ctgtaaattt cacgtattcc aaattaatgt tctccttttt
    21001 caaacggtct ttcacgttgt cccatacatc tgtatcttct ccaataatcc ctagttttac
    21061 gatagtttct tttttgtcag ttgtatctgc ttttccttgg ctacaccctg ccaaccaaat
    21121 aattgctaca aatgtaatga ctacaaaacg aataattttt ttcatttttt ctcctccact
    21181 ttcaatgtgt aattttttta atcagttgat tactgataaa ttgacttaaa aaaactaaga
    21241 ttagaatcaa taatgtagcc acaatcgtta catctgtttg gaatcgatta taccctctcg
    21301 atatagcaag attccctaat ccgcctgcac ctactgctcc agccatggta gtcagtccga
    21361 tcacgttgat gatagtcaac gccgagaccc gaatgatacc aggcaaacct tctaacaaat
    21421 acacacgtaa aatgataccg attggactgg ttcccatcgc ttctgccgct tcgatcaccc
    21481 caggatcaac ttctagcagt gcgttctcga tttgacgagc aaaaaacgga acaactccaa
    21541 aaatcaatgg cactaaagct gctttcgcac caatcgtcgt tccaactaag aaacgagtag
    21601 tcaatgctaa aagagaaagc aagataatga aagggatgga acgaatgata ttgatcagct
    21661 tatcaagtat ttcaaatagc agacggttag ctagtaatcc attagggcgt gtcactacta
    21721 acgtcacacc taagatgatt ccaatcatcc cgccaatgaa tgctgtccaa aaagacatat
    21781 atagtgtttg cttcgtcgct tcgacaaatt catccggaat caaataaaca ttgggcaaat
    21841 atgttttaaa gaaatcagtc attttatctt cctccttcga tcactttgat acgactatct
    21901 aaatcgtttt tttgtaaaat atttattttt acaccagatt tgatcaaata atccaatgct
    21961 tttttccgct gtttggtttc tccagctaaa gtaacgatca aactccctaa cggcgtttct
    22021 tgtaataact ctacattgcc atataaaata ttcgctgtta cttgatattt gctgtacaga
    22081 tgagcgatta gaggttcgtt cgtctgattt ccaatataac ttaattccac cagccattta
    22141 ttggcgatct gatcggcaaa agcagaatgg gcaatgatcg tttctaatgc ttggtcaaga
    22201 tgagtagctg ttcgaataaa atctttggtc aattcttctt caggattgct gaagatctgg
    22261 atgctgctac ctttttcaac gattcttcca tcttccataa ccgctacctt gttgcagatt
    22321 tctttgacaa cttgcatctc atgagtgatc aggacgattg ttaaacctaa ctggcgattc
    22381 aattttttta acaatgcaag gatctgaagg gtcgttttcg gatcaagtgc actggttgct
    22441 tcatcacata ataatacctt aggttcattc gccaaagctc gtgcgattgc tactcgttgt
    22501 ttttgtcccc ccgacagttg tttaggataa gcagatgctt tttcttccaa accgacaagt
    22561 tccagtagtt cattcacttt ttgacgacgt tcctgtttcg attttccaga atactttaaa
    22621 gaaaaatcaa cgttgtcaaa aatagttcgg ctttccatta gattgaaatg ctgaaagatc
    22681 ataccgatgg cctttctttc ttttcgcaat tctttgggag agagctgact cagattcgtc
    22741 tgattgacaa tgacttctcc tgctgttggt ttctgcagca aattcatcac acgaactaac
    22801 gtacttttcc ctgcacctga gtaaccgacg attccataaa catcgccttt ttcaatcgtt
    22861 aaatctacag aatctactgc ctgtatctct ttttcttttt gtttgaaaca tacagaaaca
    22921 tctcgcaatt caatcattaa aattcctcct tatctaaaaa aagcgtcctc aagaaaatga
    22981 aaatgtcatt ttcttgagga cgcttttttg cgtgttacca cctcatgttc aagctgtgtt
    23041 cacacacaac tcctcttcaa gtacgatcat actctagcaa gatatcggtc gcagccgtca
    23101 tcgccttaca tctatgctcg ggatgaattg ctcgatggcc attttccaat agtcgttcct
    23161 tgcttcttct cagctaccga agctctctgt caaaggttct tctatcgtac ttaccatttc
    23221 aatgcaaata atattcaaaa aaaaagtcct tttactaaca taaactatgt cagtaaaagg
    23281 acgacgtatc gcggtaccac cttttttcgg aagtttcctt ccctcaagcc caacatctca
    23341 aaaagagaga ttggcgttcg ttttaacggt cgaacagttc cgaatttgcc tacttatcga
    23401 caaattattc tccaaggcca ttttcagctt ttcttacttg actcttctca ccagccagag
    23461 cctctctgca aagtttccaa acttactttc cttttcaacg aaatcgatat tttgttgttg
    23521 ggattaatct acatgaggaa aactgaaaag tcaagtacga aattcaaatt attttttcta
    23581 tatttatttt tctgtttttt tatttaacat ttcaataaca gttcgaagat cttttccttc
    23641 cgcaagaagt ttcaattttt ccttttcttc gacggtataa tttcggacaa aactggaatc
    23701 aggtatcaaa acaacgccta atcctgctcg tgaagcagct gttgctccta ctaaagaatc
    23761 ttccactgca aaggctgaac tagcttctaa tcctgttcgt tccaaagctg tcagataagg
    23821 aatcggtgaa ggcttgttct ccgacacttc gtctccgaat gtaaacgtgt ccaagtaatc
    23881 agctaattta aagtgatcca agatatctgt tgctcttttc gtaacagtgg tcgtagcaat
    23941 gcctagtttc atatgacgtt cttttaagtc tgccaatatt tcttttgcat atggttttaa
    24001 gtggatggct ccgcttgtca gctgttgata aaaatattct tcacgcttcg ctcggacttc
    24061 ctgtactttt tcagggctac ctgctgcttt cactaaaata tcaaaacttt gtttccagtt
    24121 ttttccgccc caagcgtcaa cgatttcttt tgggatatgg atatcaaatt gctgaaatcc
    24181 ccaaagccag ccatcacgat acgttttttc tgtgtcaact aacaaaccat ctaaatcaaa
    24241 tattgcacct ttcatctata cattaatcct ttccaaaaca atacacatag tttagcacga
    24301 ctggtccaaa aagaacagaa gcaaagaacc agccttctcg tttataagag ttcttggaat
    24361 cgacggatat agattttctt cacagctgtc acaagcgcca gataagcgat gactgtagca
    24421 aataaccata accagtaatt gccaggaagt ggcatcaagc ctaattcagc accaaaactt
    24481 gtaaaaggaa ggacagaacc gacaataatt cctaatgtag tgataacaaa catggcaaat
    24541 gttgcgttgc tttggataaa tggtactttc ggtgtacgca gtgcatggag cactaaggtt
    24601 tgtgtccata gtgattcgac aaaccatcct gcatggaata atgcgatgaa aatcactcgc
    24661 tgtgaactat ccaatgtatg gaaacttccg cccactacag caggacaaat aacaaaatac
    24721 atcaacaagt aagtagtaat atcaaatatc gaacttgttg gaccaaagta aaccatgaat
    24781 tccccaatac tagatgcatt ccattttttt ggctcgtcca aatattcttt atccatccga
    24841 tcccatggca aggaaatgca ggaaacatca tagatcagat tcaaaaacaa aagttgtaaa
    24901 ggcagcattg gtaaaaatgg caggaacgta cttgcaatca gcacggaaaa catattgcca
    24961 aaattagaac ttgctgtagc cttgatatat ttcatgatat tcccaaaagt ttctcgtcca
    25021 gaaagaaggc ctctttccaa aatcgtcaaa tctttttcta aaaggatcac gtctgcagat
    25081 tctttcgcaa tatccacagc tgtatctaca gaaataccga tatcagccac tttcattgca
    25141 ggagcgtcat tgataccatc tcctaaaaat ccgacagtat gaccattttt acgtaaagct
    25201 gtcgtcaaac gtgctttttg ctgaggattc aattttacga atacttcatg gtcttcagct
    25261 acttgtgcta attcatgatc actcatttcc gagattttct caccggtaac caattcattg
    25321 atctctagac ctacttgacg gcacactgaa cgtgtaacta attcgttgtc cccagtcaga
    25381 acttttacag ctacaccatg ttctttcaga gctttcaacg cttgtttcgt tgtttctttt
    25441 ggtggatcaa ggaaagcaag ataaccaatc aaaaccatgt ctgactcatc tttgactgaa
    25501 aattctccaa cgacgcttgg attggtcttt tgtgcgacac caatcactcg taagccatct
    25561 tcattaagtg actgtacttt tgcaagtacg gcttcttttc gttcttttgt taatggtgta
    25621 acagtaccgc caagatcaat aaatttagaa atgttcagca tttcttcaat cgcgcctttt
    25681 gtgatcattt gtgttttacc agctggatca gcaaccacaa cactcatacg acgacgttca
    25741 aaatcaaaag gaatttcatc cactttttga taattgatct tatctgtatc taaagtttct
    25801 gttgcttcat caatgatagc cacatctaac aaatttttca gccctgtttg atagtagcta
    25861 tttagatacg catggcgcaa aacacgatca tcttcatttc cttcacaatc catatgatat
    25921 tcaagaatga ttttatcttg tgtcaatgtc cccgttttat ccgtacataa cacatcgatt
    25981 gcaccaaagt tctggatggc attcaaattt ttgatcactg ttcctttttt ggccatcaca
    26041 cttgctcctt tgaccaaatt cgtcgtaacg atcattggaa gcatttcagg tgttagacca
    26101 actgctacag atagtccaaa aagaaaagct tctagccaat ccccttttgt aagcccattg
    26161 atgacgataa ctgctggagc catcaatgac ataaatttga tcagtagcat ggatgtttta
    26221 tggatgccta attcaaagct tgattgaatt ggtttttcag atagcgtttc tgctacatga
    26281 ccaaatagtg tttcatttcc aacagaaaca atgattcctt ccgcacttcc actgatgaca
    26341 ttacttccca taaagacaag attttcgtaa cttgtttcgc tttgctgatc gtcttcacat
    26401 actttcgcat gcttttctac tggatagctt tcccctgtca atgctgcttg ggaaatgaat
    26461 aaatcctttg cggacaataa acgcatatcc gctggtatca tatcccctgc tgaaagccga
    26521 acaagatctc cacagacgat ttcttccata ggaatctctg tgtactttcc attacgtttt
    26581 acagctgccg ttactttcac aagtgatttc agtttttcag ccgcttgatt ggaacgtacg
    26641 gactgaatca acgtcattgt cccgctgacg ataaccatag tgaagataat ggctacaccg
    26701 aaaagatctt tatctccagg agctgctaat acatattccg tgatgaatga aataattcct
    26761 aatgcgatca acactaatgt aaatggcgtg atgtatgctt tcaatatttc tacaatgaat
    26821 ggtgtttttt tgccatatga aatcgcattt tcaccgtaat tttctcttga acgttcgatt
    26881 tgttcttctg tcaatccatt tgctgatgca tggaatagtt caaataattc ttgtttcgtt
    26941 tttccagcaa aagctgcata gattttttgt gtatctttct ttttttccat ctcaatctct
    27001 cctttgtgtc caaaagacag ctgttctcgc tgcttttggt ctttagctat tcatcggatc
    27061 gatagagaaa aaactgaaag gggctgagaa cagatagata atagccctgg cctttcctct
    27121 agatccttgt ttttcgaatg actgtcatcc atttgttctc atctccttta ctaagtaatt
    27181 ttaattcatg acttccaatc atttttcgaa tagttatttt tccaattaga ccacctcctt
    27241 tttatttttc accgatgggg atttgcggca acaaaaaaac ctctcgccaa atactcagcg
    27301 aaaggtttga aaaagcatat taaaaaaagc ttctcagatc tcatcgttga gttttgacac
    27361 tgtacaacgt aaaaagcaga tacctgcttt tagctacctt atgaaaagcc ttatctcgac
    27421 aattcctgtt ctacccattg gcgtctctcg acgtttttgg gcagtagcct atgtttgtat
    27481 aggagcctca cctaacaaat cttattcggt tttccttcgt taatataaca actaaaaaag
    27541 aggatgtcaa atcaattttc catgtttttc atactttttt taaaatacac acgttatatt
    27601 cctgtctcac gcggttttat ttgtctcatt ttccacctcc cgctataata gaaatatagt
    27661 aggaaacgag gtgctgttat ggaaagaaca cttgttatta tcaagccaga cggcgtgaga
    27721 cgccatttag tcggaagcat catccaacgt tttgaagcaa agggactggc cattgctgaa
    27781 atgaagtttg aaactatgac tcctgaatta gcaaaagaac attatcagca cttgactgag
    27841 cgcagttttt ttgatgaact gatcgattac atgacttccg gtcctgtcgt ttatcttgtg
    27901 ctggtcggcg aggaagtgat cgatatcgtc cgtaagatgg ttggagcaac aaaagctgcc
    27961 gatgctgttc caggtacgat ccgaggagac tacgcgctgc cggggactga aaacatcatt
    28021 cacgcttctg attcccgtga tgctgcggta aaagagatcg cccgcttttt cccgccattc
    28081 gatataaaca aaccgtctga aaaagcggcg aagtgataca aattctaaac tgctggtcta
    28141 gttgctgggt tcagcaatgg ccagcagttt tttctctaag gacctccgtt gattctttcc
    28201 taacatatat tcgagcactg tgaagaattc ttggtagtct ttcgtctttt cttcccctaa
    28261 agcagcagaa atcaatcttt gataataatc tgccatcaat gtttcataga tcactgtact
    28321 tctttcttta tgtgataagc tccgtttcat atcttcattc acactacgtg cctttttcaa
    28381 ccgaccattt tctatataaa acgaagtcag gttcattaaa aaagtaaaga gatactgctc
    28441 atgattgttc aactgtgcta atcgtcgcat tctttttttg attttcaaat aattgttctc
    28501 aatgaaccga tcactgaata tccaaggaaa atcagctaga atagatagtt caaattgacc
    28561 atagtctggt atctgcatca agtattcttc aatgattcgg cattcataac gtaaaaattc
    28621 aaattctgtc tcagatactt ctgttttttc gaccatgtga agattcaaaa ccaaataata
    28681 cagatcttct gttttcttaa aatgcctacg gttattgctg atctctttat aaggatcaaa
    28741 gctgtcttct tgtacccgat ctagcattcg tctttttttc tttaacttta ttggttcatc
    28801 cagctggttt cgcatccatt catattctgc aagtgtcatg ttcattcgct ctaaaaatga
    28861 tctcaatgtt acaaatgaca tttttttcac tgaatttgtc tcaatcccga ctagagaagt
    28921 cttaaaacag attccttccg ctaattggga ctgtgtcaac ttcttgttga ctcgaagttt
    28981 cttgatcaat tcaccatcat acataatagt tctccttttt aatttaaatt tttccacatt
    29041 caataaatag atacgttaaa aaggaaaaat acacgaaaaa aataaaaaaa tgtttttttc
    29101 ataaaaaata ccaaccttca agcattagaa tgttgtctaa ctactgaagg ttggtttgat
    29161 tgtttattga ttattttttt gctgttcaac gtctgttctt gttactggat ataagttggt
    29221 tgttgtttta ttaccatttt ttgaaaagac acttgtcgaa tgttcgcctt tttgcttttc
    29281 gattgcttca ttacgttccg cttcattttt atagtcatat tttttcggat caatcgtctc
    29341 aaatccgttt ggcacataaa accgcaagag attttcctga ttcagcttat ctgaaagact
    29401 taacgcagtc ttgacttttt cctgatcttt ggagatttcc tcatcgattc ctgctgcttt
    29461 cgtatcgatg atttctcctg tctgattatt gtaagctttt cctcctagga cggtgtattt
    29521 gggtgtcaca aagttcccat ttcgaaaagc aactacttga tcatgctgag aagataataa
    29581 gtctgtacca aaatgaagat aatctttatc atcgattccc aatagatgta gtaatgtcgg
    29641 caaaacatcg atttctccac cgtattcatg attgactgtc cctttagtat aaccaggcat
    29701 atggatcatc aatggcactc gttgcatctg tgcgttgtca aattcatccc atgtatctgg
    29761 atctttacca agagcgcttg ctaaatcttt attatctgta ttcgagatcc caaaatgatc
    29821 cccgtaaatc acaaagattg aattttggta aataccagat tttttcaaat acgtaaaaaa
    29881 ttgttccaat gattgatcca gataatgtgc cgttcgaaca taattatcta ctgtgctatt
    29941 gccagtattc aaagatggaa agtcgaaatt cttgtcatcc gtataataag gcgtgtggtt
    30001 ggttacggaa agaaatttcg tgtaaaacgg ctgttgtaga tgctcaagat attgggcaga
    30061 ttctctgaat aaatctttat ctaatatccc ataacctaac gtttcgtcgg attcatcaaa
    30121 ataagatcga tcaaagaaat tgtcataacc taagttttta tatacatgat ctctattcca
    30181 aaaactagct acattcccat ggaaaacagc gcttgtatag ccttgctttt gtccaaggat
    30241 cgctggtgcg gcttgaaaga cattgtctga cccaagttct gtgaataatg agccttgagg
    30301 taaaccaaat gtgccagttt ccaacatatt ttcagcatca cttgtctttc cctgtcctac
    30361 ttcatgaaag aaattgtcaa agctgatcgt tgcttgattc tggaaaatac tatttaaaaa
    30421 cggtgtgact tcttgtccgt ctaccttcat attaatcaaa aactgctgga aactttctaa
    30481 atggagaacg atcacatttt tccctttagc gatcccaaat gtttcgggat ttggctctgc
    30541 ataatgtttc tttgtataat ctaaaacttc atcaatccca ttactgcttg catgcgcgcg
    30601 aacactgcta gtcattcctg ttttgattcc gtcataaata gtatacgcat cgattcctag
    30661 atatttgaca atatatgaac ggtcaaatgt tcgctgcagc aattgtggac ggttggcttc
    30721 gctcagcgct agatttcctg aaaaaataag ccctgaaaga caggtaacag cgatagccat
    30781 cggtttgccg acagggttgc ttttgatagg tattttcttg accttcaacc aaaccagtag
    30841 cccaatgaac acagcgatat ccagccagta gatgacatca tggggcttca tcaaagaaaa
    30901 ggagcttcct gacaatcctt gcgacacttt cgaaaagcct aatacagatt tgactgtaat
    30961 gaaatctgtg aattcccgat aaaaaataat attcaagtac aacaaaagcg tatttaaaat
    31021 atcaatgatc aaaagaatag ctaacgctgg ctttggcttt ttaatataca aagaaaggcc
    31081 aaaaaacaat aaggtagtcg caattgggtt gatccacaag ataaagtact ggatcgtacc
    31141 ttccacacct aatgaaaaat ctgcatagta ggcaatgatc gtcttcagcc agaaaaagaa
    31201 aacagctgtc aaaacgattg ctaaacgatt ttggcacaat tttttaagtt gtgtcacgta
    31261 tatcacttct ctctattcac attttttctt attttgctcc tgaaaaatga aaatttccta
    31321 aaaaagttgt tatcttaaga tttttttatt ctttctaaag attattccgt ccacttttca
    31381 cagcataaaa ccgctgcgat gtaagcgatt aaactaatga agagataaaa gtcttgtggt
    31441 gaccgcttca ctccacggta ttcaaaagcc agtttctcgg tattcgtaca aaaaaagagg
    31501 ctgtgacaaa attcttgtcg cagctcctta tttcttgatg caggacagct ttttcacaac
    31561 ttcttcctta aacggtgttc tcctgccaac tcctcggcca caagtcacaa tatttataaa
    31621 acatgagaag ctgttttttg aaattgttcc ttgtggctca gagttaaacg gcaggctcaa
    31681 gacctcttga tacacggtgt tcaatcagct gaccctcggt attagattat gtcaggacgc
    31741 taattttaca acctcttggt aaacggtgtt caaaagcttg catctgcggt aataagccca
    31801 accaaacgaa aaatataagg agctattttt tgaaattgct ccttgtggct cagagttaaa
    31861 cggcaggctc aagacctctt gatacacggt gttcaatcag ctgaccttcg gtattagctc
    31921 aaaaaacggc aaaatatgag gaactatttt gccgtttgtt tctctaatac tcaggtcaaa
    31981 acgctgattt cacaacctct gtttttcatt gtccatagga ttgatattgt ccttgtgatg
    32041 actcattcgt aataattgag gcttgatttt cttcacttcc cgttatcgtt tgtccactgc
    32101 cagaatctga aggacttgtt cctgtcgact cgtttttttg agaagagaca gttgttttct
    32161 tgacttgttc atttgtcttt ttccattccg ctaaacgatc ggcgaccact tttttgtcta
    32221 ctttttcaga ataagcggtg atcacttttc catttttcaa acgggctact ttgtcgccat
    32281 catgagtcaa aagcaaaacg gtcaaatgct tgtctttaaa ttgatattgt ctgagagaaa
    32341 tcgcactaag tacgtcatcg atattaataa attgattttc ttcttttcct tttggcaaat
    32401 aaatgtccaa ttcgcctttt tcgtaattgg cagttatttt atactccgcc caccaataag
    32461 ttgagaattc ttttttgaaa ttatctactg attctttgct tgctacgatt ttttctgttt
    32521 ctttctgagc aagatctgct gtcatttttc ctgaaaatgc tgcggataaa ataagcagta
    32581 agaaaaaacc gaataaccaa aagagaagaa acggtctttt tttcctcatg ctttcctcca
    32641 ctcctattta attttgacta ttctattata tacaaaaaat gaaatagaaa gacaaaaaag
    32701 ttgaaaaaga tcgtaaataa ttgaacttct ttttcacaaa atggtaagaa tggagaattt
    32761 cacgcatttg ctctcaacta ttctttctta agcctcaaat ccgtttttat ctgatacgtc
    32821 tttgaaccaa tgacccgatt ttttgattgt tctttttcca tcttgtgcta agtctactga
    32881 aataaagcca tatcgattct tatatgcatt ggtccacgac cagttatcca tacatgtcca
    32941 catatgatag cctaaacaat tggcaccttc ttgaatggct tgatggacat atttcagatg
    33001 agattggaca aattcgatcc gataatcatc gtggatcatg ccatcttctt tgataaatcg
    33061 tgcttcgttt tctacaccca taccgttttc agaaataaag cagtcgatat ttccataatg
    33121 atctcgtaca ttgatcaaaa tatcatagat tccttgttca tagatctccc atccgcgata
    33181 aggattcatt ttacgaccag gcatttcata attgtcgaaa taatcctcag gcattggacc
    33241 gtttttagta tcgattggtg tttcttttgc ttttacccgg cgtggctggt aataattgat
    33301 acctaaaaga tctactgtat tttctttgat aaccgtcaaa tcctctgcat ggatcacagg
    33361 catgagatca agttctttta ctatctcaat caattcactt ggaaactcgc cttttacagc
    33421 tggatcaagg aatgaacgat tgaagaacgc atctgctatt tgcgctgctt taacatcttc
    33481 agggtttgat tcgtctcttg gatagcttgg tgtcagattc aagatgatac caataacacc
    33541 accttgctcc atttcatggt aagatttgat ggctaacgct gaagccaacg cttcatgata
    33601 gccaacttgg atcgcttttt tcatatctga ctcttctgga taatgccatc gatataaata
    33661 acctgcttcg actggaacga ttggttcatt atgagtaaac cattttttta ctttcgaacc
    33721 aaacaattca aaacaacttt tggcatattt ttcataggct tcaaccgttt ctcggttcaa
    33781 ccatccgcct ttttcttgca gatacatcgg catatcgaaa tgatacagat tcacaaaggg
    33841 ttcgataccg ttttcaatca actcatcaaa ataacgatga tagaaacgaa cggcttcttc
    33901 gttgattgtt ccagattcat caggtatcaa acggctccat tggatagatg ttcgaaatga
    33961 attatgccca gtctgtttca tcaactgtac atcctcttga tacttcgtat aaacttgcga
    34021 ggttttttca ggtcctactt gatcaaagaa cttttgcggt tcttttttgt accaataatc
    34081 aaaaatgttc tctccttttc catcgcctga aatccttcct tctgtttgtg ggccacttgc
    34141 tgcagaaccc caccaaaaat ttgctggaaa ttgatatttt ttcatcaaag cacctctttt
    34201 tcttttttag ttcgttttag ttgattccat gtatgatatt ttccatcaca atcacttttt
    34261 cattttcttc ctcttctttt ttgattcgtt ttaacagctg ttctgctgct cgttccccga
    34321 ttttatctgt tggtggcgtg atcgtgattt tcggaaggat actcagatcg tttttatcta
    34381 aataatcata gtgactgaac gcaatatcct tcccgattct gacaccttct tgattgaaac
    34441 attcgatggc accaatcgac atattgtaat tgctgacaaa aatagcagtt gccccttttt
    34501 ctaataatgc ttttgccccg taatagccgc tttttctaga atagtctcct gtaaagacct
    34561 ctaattggat cgatggatca ttttggaccg cttctttggc tcctgctaaa cgttctcttg
    34621 ctacgtagtc tgtttgagtg gcagcaataa atccgatttt tttatgtcct tgttcaccat
    34681 gatgagcgat cacttttgct acactttctc gatcattcac taatattgta tcaatacctg
    34741 ctggtccttc tggacaattc aatgcgataa ctggaatact catttttgtg agcatttcaa
    34801 atccagacca ctcttcttcg gataagaaga caatcagccc atcgatcaca tgcttcatca
    34861 ggtattcaat tttttgttca attttttctg gctgatcggc aaacccgctt aataataagc
    34921 tatacccatt ttcttcagct actctttcga tccctgagac aacttccgac ccaaaacggc
    34981 tggaaatccc gtttatcaaa agtccaatag agaagcttcg attattcttc aaccctttag
    35041 caatgatgtt ttctttatag tccaacgctg aaatcgcttc tgctattttt ttcatgttct
    35101 tttccttcag ttgctgacca ttcaagtaac gggaaactgt tcccactgaa acaccagcca
    35161 tcttagccac atcacggatc gatgccatac attctcactc ctgccagtta catttgattt
    35221 ctctttcttg ttgttcgatt atgatgaccg cattctttgc atagtgttgc ttgtcatcaa
    35281 tatccatata actaaagtct tcagtagagc aacttcctct cactattaat tatacttaaa
    35341 caagtatttg aaccggttca tttttaatat agcatttttt taaaagattg caacactttt
    35401 ttaaaacgct ttctgaaagt ggcggatttt ttgccttttt aaaattttat tctaaaattt
    35461 actctatttg tgggtgtttt gtgcgttttt ctcttccatc cgtttgaagt tttacattcc
    35521 aatggtataa tttctttatc ctatcaaatg ggggaagtat tttgaagaaa ttaatcgtac
    35581 tatttatttt gtctgcggga cttttgacat tgactggctg tgatttgttt ggcggctctg
    35641 accaatcctc ggacgaaaca accgattctt ctgtcttaaa agcggaaaaa gcagatacca
    35701 ccaacagtgt atatacgcta aaagtacgta aagatatgga tttatccgcg ggacagttga
    35761 catttacaga taaaaaaatg gaatggacac gcacgtatca gacacaagga actgattctt
    35821 ctgaatcatc tgaagaaaaa acagtgctga cagatatcaa gatcactacc aaagatgacg
    35881 aatatattat ttcaggaaaa gaaaataaaa aagaaacaac agtcatattt acaaaaatcg
    35941 gtaattaccg tttgaaggat gaggatggca acatctacag tctatagtgc cgtctgttgg
    36001 atcttctttt gtttctcccc ttcttttctg ctatagtaaa gaagcaagat gattgtaaag
    36061 gagacgaaat ggatgatcga tagtcctgat tattgtacat gtaataacaa caaaaatatc
    36121 catacagaat ttaatgacca aggaagcttg agcatatgcg acaactgtca caaactagtc
    36181 aaagattcat ttaaaacatt tgaatcttat cctgttcaaa attatgtaaa aagtagaaga
    36241 agataaacaa atccaagcaa aactcactat ggctgatttt tatgaacttc aaactcagct
    36301 tcttcctttg atcaagcttc atcagtaaaa caaacagtgg atcatttcag tttacaaatc
    36361 aaagagtaaa gatttattta tttcaaatat ttgaatataa aataaccaaa cgatagaaag
    36421 gcttattcta catcacgtag taatttttct ttcccgtcgt ttggtttttt atttttagcc
    36481 taattcttga ccttttgcat gctggttatc cgtaaaatat tttccagcag gctttccttc
    36541 caattcagct aatttttctt ggatctgacg gatcaccttt tttgcatctt ctggattttc
    36601 tacaaaatcg aatttatccc catccacttg tattttagga catacatcaa aatcttcata
    36661 ccattgatta tagcgggtgt tcaacgtttc ataataggta tataacgtct catcgctttc
    36721 tagctgttca tagtcacgcc cacgtttttt gatacgttct agcatcgtgt ccaaagaaac
    36781 tttgatatgg accatcaaat caggccgttt ttttggagca acatcatcta actcgtttag
    36841 catcgtatct aataagctat cgtactgctg tacttcgata tccgttaccc gacctaaatc
    36901 agcgtttaga tggaacaaca ggctatcttc atagatggat cggtctagca cattgtcatc
    36961 gttcactaaa gcatttttca ttgctaaaaa tcgcttgttc aaaaagaaga tttgcaataa
    37021 aaaagcgtac tgctcaggat ttgaataaaa gagcggcaat acttcgttat cttcgacatt
    37081 ttcataaaat ggtttagaat caatctcttt tgcaagcata tccgtcaaac tgctcttacc
    37141 tgcaccaatc gttcctgaaa tcaaaatcac tgacatacaa cccttcctct tctataagta
    37201 ctcgcctacg taagtttcaa caggcaatgt ttcaaaatca tattcacgta cagcttggtc
    37261 tgattttaaa tacgtatgga gactttgtgt aatcatcaag ttcgtaggta ccgtctcttc
    37321 ttgtacaatg atcatcggtt ttttcaacat agttgccaca cctaattcgt aagccgttcc
    37381 tggatcgatt gtttgatgct caaagtcaag gatagcaaca acaaattctg catttgtcag
    37441 ttcttccata tctttttcgt atacttcctg cgcccatcca gcgctgaata gttcataatt
    37501 gctttcttgg tgatgacgtg gagagtagaa acttgtgact gttttgtttt cctccaacgc
    37561 tttttcgata cgacttactc gatcgatttg ctcctctgaa aaaaatggtc ctgctaaata
    37621 tatttgactc attattttgc ctccttcaat aataactgat ttttaataga tactgctcgt
    37681 aattcattga ccagttccaa tggattgttg gaaaagatta cttgatccaa ccatttttta
    37741 tccataaaat cctcttttgc aaaagtttct aataattgtt gcaagccgct gtaataaccg
    37801 ccaatattca atattccgat tggcttgtcg ggcgtcagac cgattgctat ccaagaaaga
    37861 agttgtgaga attcctccaa tgtacctaga cctccaggga aaacgaggac agcatctccc
    37921 ttttcaaata ataatacctt tctttcatcg atcgtttctg taggaataaa tgtagtaaca
    37981 tcttttccag gcaattcagt ttcaaaaagc ccattcggat agatacctgt gacttttccg
    38041 ttattttcca gtactgtttt actaatcact cccataatcc cggagtatga accaccgtaa
    38101 accagttcga tttcttcttg tgccatgtat tttcctaacg tttgcgcaat aaatttgtaa
    38161 ctttctttat taccaaaacg ggaaccgcaa aaaacagtaa gtttcataaa aaaacactcc
    38221 ctaactcaaa agtctatctt cattctacac gtgttttttt aaaataaaag actagatttt
    38281 gtagtttttt agtggtatat aggatagacg ccactatata tagtatttag aaaaaaatca
    38341 tttttcagcc attttataga taaaacaaaa ataaataacg tgttttcatc gatatgaaat
    38401 gacttactta tagaagatac tgggatttcg tcctatatgc caataacgtg tattatttta
    38461 aacaacaaat acttgtttct tttattaacg aaaaaatcat tttgttctcg tgttatgttt
    38521 cactgataaa tgatgtttct ctaaataaaa aagccgacga actaaacgat caaaatttga
    38581 tcatttttgt tcatcagctt ctcctaaaaa tctttttgtt aacgataaat agctggattt
    38641 gtaaaaatat cacttgaatc gtcactgctg gaagaaaatt cagtgataac cgcacctgtt
    38701 gcgcctgcct ggaactagtg tttgatattg ggctcgaacg tgtactgatc tctagcatga
    38761 agaataattt ctttttttac tgtataataa ctttctttcc tttttggaat agtacaggaa
    38821 agtttttttg tttcctttcc ttcgacataa ggtataccag accctttcga caacgaaagg
    38881 ttctcatttt tccttcatcg tcatttcaag gagggtgccg atgctctgga cagtttcgat
    38941 cgctcctaaa ccaaaatctg tatattcgat tctttctaac tctgattctt tcataccatt
    39001 cctgtctcaa ggtacatcta ttgtactttt ttcttgtaat ccattctgcc tctcctaact
    39061 aattgtcaaa tcatcccaag atatgtcttc ttcctctttt tcttcttgga tgatttctgc
    39121 attcggatct actggttttt tcaataataa aatggttatt cctgtgacaa aagaaccagc
    39181 taacaatgca ccaatgaatg cccatggtct ggtcatcgta gcgactgcaa acattcccga
    39241 tgccggaata cggctatctg cgccccaaaa catgcttaat ccgccaccta ctgtcccacc
    39301 gactcccgtt gctatgacat tgcgtgccaa gtcgttcaat acgataggga aacatccctc
    39361 tgtgatctga cagatcccca taggaaaagc ggtcttcaat gtatcgattt cttgacgatt
    39421 gagtatattt ttacgaatga ttttccctaa gaaataagcg atcgtcaagc cgaatggggt
    39481 taccatcgaa gctaaaatca atacagtgat tggttcatag attccttctg aaaatcgtgc
    39541 cacaccccct tatccagaat aaatggtaat ccagaaacag ccgtgtatct gcggtaataa
    39601 gcctaaccaa acgaaaaata tgagaagcta tttttgtttg gctgttctta ttacttgatg
    39661 cagggcagct ttttcacaac ctcttttttt atttatgttt cataatcaat atggtaagga
    39721 tgcagctccg tatggtagac cgcctccgaa tattcaatca tttccccaat ttgcgtagac
    39781 gatttccgta tccgtttgat gccgatctgt gcgtctgttt tcagaattcc ttgttcttct
    39841 tctgttaaaa atactgccga gaaatcatca gaaaatgagt caatagtata tccttttttc
    39901 gtcagcaaac gatacaaaga ttctttgcca aattcttctc tgctgaattg catcatttct
    39961 tgtggaagat aatgaacaaa ataaatataa ggctgattgt tcaaataata taagcgctta
    40021 aaacaaacag cttgctcacc gaaaaaggaa aacaaaggat cttccttctt tatatggacc
    40081 aattgcaaat ccagcgtttc tttccggact tcatatcggg agttctccaa gatttgcgta
    40141 aagcttgccg ctttggataa tcgattgtaa ggacgattgc ttagaaccgt cgtcccacga
    40201 ccacttttct ttgcgacata ttcatctgat gccagcagtt cgattgcctt tcggacagtg
    40261 attttgctga cttgaaacag ttcttctaat tcactttctg tcggcaacat cgaaccgact
    40321 ggatattttc ctgagaaaat atcttcttta attttatctg cgacttccaa gtatagtaca
    40381 cgtgtccttt tcataacgtc accctttgct ttactattac taaaagaata gcacataaaa
    40441 aataaaaaaa gaacacaaat cacatgtgag aagtgtgttc tttttcattc agctgcttta
    40501 attacaagtt tacgccattt gaggcaatta cttctttata ccaatcaaaa gattttttct
    40561 ttgatcgatt cagtgtccca tttccttcat cgtctagatc cacatagata aagccgtaac
    40621 gtttactcat ttctcctgtt gatgcactga caagatcgat acatccccaa ggcgtatagc
    40681 ccatcaaatc tacaccgtct gctactgcat tagccatcgc ttcgatatga cgacgtaaat
    40741 aatcgatccg ataatcatca ataatcgtgc catcctcttc catatgatca atggctccaa
    40801 gaccgttttc aacaatgaat aatggtttct ggtaacgatt gtataattca ttcaatgcga
    40861 ttctcagccc ttctggatcg atctgccagc cccattcact tgcctcaaga aacggatttt
    40921 ttactcctcc cagcaagttc ccttctgaag ttgctgcttg tggatcagtc tcattgattg
    40981 ccgtagacat ataataacta aatccgatgt agtccactgg atattctttt agcaactgga
    41041 agtctttttc cgtttgctct aatttttccg gatcgactcc atatttttta tgggtacgcg
    41101 ctgtgtatgc agggtattct ccacgtactt ggacatccgt gcagaaaaaa ttgaattctt
    41161 ggttttggat cattgttgct gcctgattga ctggattggc atcgatgctg taagttgttg
    41221 catagataat catgcagccg atttggatat ccgaacgcaa ttcgtggccg atttttacgg
    41281 ctttgctact tgcaacgaat tgattatgcc atgcttggaa aatattttgg tactctcctg
    41341 ctccattgct ttttactaat ccttgactta aagctggaaa gtgaaaggcc gaattgattt
    41401 cattgaaagt catccaatat ttgactttac tgctgtatct ctctaatact gtctgagcaa
    41461 atcgttcata gaagtcgatc agttttcgat ttttccagcc accgtattct tttgccaaat
    41521 gaagaggcat ttcgtaatga gaaatcgtga tcacaggttc aatatcatat tttaagcact
    41581 catcaatcag ctgatcataa aattctaatc ccgcttcgtt aggagtacct tcgtctccat
    41641 ttggaaaaat tcgtgtccag gcaatcgaaa aacgataaca tttgaatccc atttccgcaa
    41701 acaaggcaag atcttctttg aaacgatcgt aatgatcgat tcctcgatga ttcgggtaaa
    41761 tatatttttc ttgatcaatc gtccagtcaa attcttcact gccgataatc gcaaagcgct
    41821 gcttacctcc aggcatagca tctgcaacgg atagtccttt tccgtctcga tcataagccc
    41881 cttctaattg atttggcagc agttgctcca ccccataaaa atttttctga aaaacgtgat
    41941 tgcatcctga tttcctcctt attttacaat tgccagaaca tcttcgtttg caataatctc
    42001 tttttggtct aattcaagta tatcggcaaa tgcatcagta ttcgtaatga caactggagt
    42061 gattacgcta tagccagctg ctctaattgc ttcgatgtca aaacgaatca ataaatctcc
    42121 tgctttgacg agatcccctt gtttgactaa gatctcaaag ccattcccat ttaattctac
    42181 tgtatccatc ccgatatgaa tcaaaatctc cgctccgtca gtcgttgtga tccctacagc
    42241 atgtccagtt ggaaaaatag tcgtgatctc tccgtctgca ggtgcaacta gttctcctac
    42301 ttctggatca atagcgatac cttttcccat cacgccagaa gaaaaaactt ggtctggtac
    42361 ttcactcaat ggcagtactt tacccgttaa aggacttttt aaggtatgcc gtgctgaagt
    42421 aatcggttct cctgcattcg catgtttgtt ttctaattga ttgtcttgtg tttgttcgtc
    42481 aaatcctaaa atcaatgtac ctacgaatgc aagaacaaaa gcaattcctg tagctattac
    42541 tgctactgtc acatttgact ctacaccatc caccgtatta atgaaagtcg gaatcgtcaa
    42601 taagctgacc aaactgctgg agaaagcttt tactccggaa aatccgataa tagctccacc
    42661 aatacctcca gaaatacaag cggcaatgaa tggtttcttc aaaggtaatg tcacaccata
    42721 cacagttggt tcagtgattc caaataacga agtcactgta gaagaaatcc ctaatgctcg
    42781 aagtttcgta tcttttgttc gcaatgctac agctaaagca gccccacctt gtgccaagat
    42841 ggctggaaga agcattggca tcaatacatc aaacccatat tgttcgatat tcaaaaacat
    42901 gatcggtacg aatccccaat gcatgccgaa catcacgaat acttgccata aacttcccat
    42961 gattagacct gctacgattg gactaaatcc ataaatcgag ttgaagagac cgcctaaagc
    43021 attaccggca accgtcccga ttggtcctaa agcaagaaat gttaatggaa ccatcactac
    43081 taaaacgaca agcggaacta aaatcatttg cagaaattgc ggaatcactt tttttacgaa
    43141 tggctctaat ttactttgaa cccatacggc tagaatgatt ggtatgacag aagaagtata
    43201 accagatggt gaaagaatca ctgggatccc aaagaaactg atagcttctc ccgcaccagc
    43261 aactgctgtg atagctggat acacaagtgc catagcaatt gctactgcta aaaactggtt
    43321 ggctttgaac tttttagctg ctgtaaaagc aagcatgaca ggtaagaagg taaagacacc
    43381 atctgctgca gcaaacaata tttgataagt accgctatca gctgtcagcc agcccatcac
    43441 cgttgccaat gataagaatc ctttcaatac cccggcggct gccatcgccc ctagaaaagg
    43501 tgtaaatata ctagagataa tatcgatcag acgattcaaa atatttttgg actcttcttt
    43561 tccatcctcc gaaactgcaa gaccttcctc atccacgatc gattgataaa catctgctac
    43621 attactgcca atcactactt gatactgacc gccactttgt acgacttgga tcacgtccgg
    43681 gtcttctttt aacttttgcg tatctgctaa agattcatct tttaatctga atcgcaaccg
    43741 cgtagcacaa tgtactaaac ttttgacatt cttttgtcct cctaccgctt cccatacacg
    43801 acgaccaact gcttgattat ccattgtttt ttccttcttt cttttttatt taaaaaataa
    43861 aaacccagat tgaaaaaaac agtcacaaac attcgtgaac ctattttttc aatccaggtt
    43921 ttgcctgcca tacagtaaca atccttatga ttggatgctt tttttctcac ttactactct
    43981 ttgaatatga atcgttaaat aaatctgctc tgcgatcccc atttcctgtt tttgcgtttg
    44041 tcgaagatac tcattgatcc gttcgacaca atgaaacgct tttggatact ttccttgaac
    44101 taatgcgtag agaaattcat cttgctcgtc agatccttcc cctttgagat aacgctgggc
    44161 aaaaaactgc agatgagtaa tgatacgctg ataattcaaa gattcttcat cgaacacgat
    44221 gccgaagaat ttactgatga tactcagtat atctcttacc attgtggtag cggtcatcgt
    44281 cacttgcatg tcttcgtttc cttgttggct attcacaaaa tgaaaggcaa taaaaccggc
    44341 ttcatcctca gaaagttcca cacccgtctt ttgtttcacg aacaaaagag cctctttcgc
    44401 tgcttgatat tctttcggat aaaatttttt tgtttcaaat aataatggat taggcagttg
    44461 gatattttct tttgctcgtg tgatcgcata atgaagatga tcggtcaatg tcagataaat
    44521 attaggcgaa aattcaactt ttagtttatc ttcagccagt tcgactactt gtttgaccca
    44581 ttcgatctcc tctgccggaa tatcagccat cagctgctgg aattggtttt tagcaaaaga
    44641 atctcttaaa caaattcttt ttggaccgct tctggcgaaa tctcgtcccc aatctttttt
    44701 tgaaaagcta gtccttttcc catacaaacg acttcttccc cgaatccatt tttcgaaatg
    44761 acgacattgt tattcaaaat tttatcaatt ttcattttgc ttcgccctct caagaaaaat
    44821 aaaaaaacct agaattcgcc tactgtttct tagctgaatt ctggttttgc ctgccgtaca
    44881 gtaacaatcc atttcttatt caaaatcatc ataccatcga atttttattt atgcaagcct
    44941 tttcatataa aaaataaaaa aactggaaca caagtctatc tagaaaacaa ccaaatcaga
    45001 gatgcacctc tttgcgtttc tctttttttc agcaaattgg tttttcctta tcgattcata
    45061 tcctttggct gtttttaatc tgtaacgact tatgtcccag tatcctaaaa tgtttttgtc
    45121 tctagattga aagcagatct catatcatct gtcgcatctt ttatcgatgt aacactttcc
    45181 agttctcctt gtacaactag tcgcgtgacg gcgtccatgt cgccacaagt aattagtgtg
    45241 acaatttctt ttccctcgac ttcattcagt aattgggtat ctgtaggagc aactttttct
    45301 ttaaaaaatg ttttgtatgt atacacattt tctaaatctg tcaaatagat cttggcaccc
    45361 atctctaaat tttctagcgg tgtaaacagc aattcagggt tcgttgcacg atggcttgct
    45421 aaggcataat ttccttttcc catttcttga tctggagata atgttcctgc tccgtaaagt
    45481 agtgacgtat tatccaagcc tttgaaaacc ggtaaattga ttgaaactga agggactgcg
    45541 atactagcaa tcactggtag atctgttcct ctcatttgcg acctcatgac cccttctgtc
    45601 gtcattggtt ctaccgcatc aaagtcaaaa ctgacatctt tatcgttatt ctttttcaga
    45661 tcttcttttg ttacattcgc tatagcatat ttatctcctg tctctctgac aaaataatcc
    45721 ttgatctgtt cattgaaaat caaagctagt cctactaata acaagaggaa caagaggata
    45781 ttgactagcc atctttttgc ttttcctttt tttttcattt tctctccctc cagactcatt
    45841 ttactgtttt tcttttgctc tttccaacag ccgaatgaca catttctaca actctgtgta
    45901 tttttttcgt acacctgcgc ttttttctac aggatatttc aaattatttt tgatcaattt
    45961 ttcttcaatg atctcatcta gatccaggtg aaggttgtct gccatcatgt atgaatagat
    46021 caatacatct gccagttctt ctttgattcg ttctaattgt gtttctttta cttcttccgg
    46081 cgttttccat tgaaaaagtt ctaacaattc agatgcttcc aaagaaatag agatagccaa
    46141 atctttttcg ttatgaaatt gtcgccaatt acgttcatct ctaaactggt tgactttttc
    46201 catactattc atttgcttgc cttcttccaa tcacttctta cttgattaat cataccattt
    46261 ttttacataa aaaatagatg atgcttttaa aaaaactcct gttttctttt atttaaaata
    46321 aatgtcatag aaaatcaata atttaggtag ccaccatgtg tatgcagtag cgtgtcttct
    46381 tcccttgagg ctttttgttt ttcgatacgt tcttcttccc aaacagacaa cgctactaga
    46441 atctctctta atgattttcc ttcttcggtg agcgagtact ctactttagg cgggacttgg
    46501 ttataggctt ttcgatggat actttcatct tgttctaact ctcttaactg ctgggtcagc
    46561 attttttttg tgatcgtagg gatttgcttg cttctccacg cctaaaataa gcgatattgc
    46621 tcttcccttt atctggtgta agcaaagcag ttagcatttt gacgatcgtg ggttccgctt
    46681 ttcacttctt atctacttag tatcatgaag tatactttcg tactaatact aagtagcgga
    46741 agtgtcaact actttgttta actacatagc aaaagaaaca gaagggtgac aacggtcatc
    46801 acgcttctgt ttcttttgaa tatgctgtgt tgttgtctct atctccgtgt agactttcct
    46861 caaacttatc ctttgacagt aagtcagtag gctgatttgc tctttctaga tgccagatac
    46921 atttctacaa aaaaatagtg attctgtttt gaaaattcga tttttagttc tgcattttcg
    46981 taaacatcca acattttttt cgcactgtat agacctaacc cgccattttt tttagaggtt
    47041 tttcctcttt tgaccatctc cgatagcgtc aaattcgttg gatttgcctt gttcgctata
    47101 ctaaaacgtg atccctcttt ttcttccagc agattgatcg taatcggact ctgatcggct
    47161 acacgatgat cgaatgcgtt agaaataaaa atagataaac agcgaataaa aacaaccaga
    47221 tcaatcggga ttgttttcac ttcgacagga ataactactt ggatcgggat tttctccgat
    47281 tctgcttttt ctagaaattt taaaaagaca cccctgacag ctggggatac aatatttgtt
    47341 agctgttgta tttgcggttt ttcaaaaata gctgcagaat gatcttctaa tatttctaaa
    47401 aattccaacg tttctttttt attttcctga agagtaattt ttaatgaaaa cagtagactt
    47461 ttataatcat gtttgaattc ctctagatga tggtaatatt cttcatttat ttgatacagt
    47521 tgaagcgatt cctgatgttg tctttctttt acttggaaac tgatcaacat aatggaaaaa
    47581 aacaaagaaa aaaaactgat gactatcgac aaaagagata gaagcagata attagatgag
    47641 cggaagtgaa cacttcccaa taccaagtaa atcacgcccc agcttaataa aatacaaata
    47701 cctccaaaat agtgttcagt tggataagta aaaagcaagt tgagaaatct cgtctgtttg
    47761 tctatacttt ttactaatag atagaaaata aatgcgataa gtagtgcaaa aaaacttgct
    47821 gttccaagat gtctctttcc taaataatcc atcagatcaa aaaccagaaa aaagctgagt
    47881 ccagtgatag caaaaaaaag attactgatc aaacagctga taaacaggtt tttcgtagta
    47941 aaataaaaaa gaaacatcaa taataagcca actaggtaag gaaagctcac tttagggata
    48001 ggaagtaaaa gtgtcaccac catcaaagct atacaaccaa agctgttttt tactagcagt
    48061 tgtttcgaaa agaataaata gatacctaaa tctaaaatca aagtaaaggt caaataaagt
    48121 gtcactgttg cgaccatctt attcctccat tgttttgttt caaaatgtac acatattttt
    48181 ttaataggag cctgcatatg aaaaagtatt ttatcataga agataaccag tttcacagcg
    48241 aatggatcat cagagaattg gtcaatcatc atatcgagaa tatcgtgcag ctcacttcta
    48301 tctctcaaat caatcagttg atccagttgg gcactattga taatcacgat gttttcttta
    48361 tcgatatcga cttgaagcaa tcactcacag gtattgatgt cgccgaacaa atacgtaaaa
    48421 aaaatgcaca tagtaatatt gtttttttca ccgcttatac gaattttgca gtagagatca
    48481 tcaatcggaa aatccttccg attggatata tcagaaaaga caggaattta tctgaacaaa
    48541 ttcgtcaagt gctagaacag atcaattgga aagaacagca gatcgtaaat gtcgataaaa
    48601 tctttattga tcaaaaaggt ggaagtctcg tcctgtatcc tcgggaaatt ttatatattg
    48661 aaagtatcaa aggtttgaaa aaccaagtta tggtcaaaac aactacagaa gataaattag
    48721 tgaatacttc tttaaaacaa ttgaagacag agttagaaaa gtatgcttac tttttacttt
    48781 taaaatctta ctgtatcaac ttatcgcaat tgcagaaaat tgattctgct cattatgtgt
    48841 tagaattttt caacggtgac tccttactcg ttggtcgaaa gatctttgaa aagacaaagg
    48901 aacgtttcca tgacttccaa aaaactgctt cgagttgatg aataagagct gagacgtaag
    48961 catagcagat ttcagggagt gggccttgaa tcggctccac tccctgaaat cgttgatatg
    49021 attttacgct tcctcttctg taggagcatc tgttaacgac catgtgaatg ttgaaacgta
    49081 gttgtctaca gcataattgg atacaggaac aaataattcc actgattgtc tcccttgttc
    49141 cacattctct cctaatgaat aaatccatgt gccaatccct tcatttgctc ctgcagttac
    49201 tagatctact gcctgatctg ctgggatttc gattccttca gcgccagttc cagaaacggt
    49261 agatggcatt ccactgctat tagttgcgct atttcgaatc acggcgtttt tgaatttcac
    49321 ctttgaacca gttagtttat tcgtatcaga tgttgtacca ataaattctg ttcgtttgac
    49381 tgataatttc caaccggcat aatttccgct tttatccgtt acttgtacga aattctgtac
    49441 ttgtgtttgt gctccagtac tgtccgttcc gctttgtaat gcagcatata ctgtttttgc
    49501 tgtacctaac ttgattgttc caaaatcaag atctggagct tggtcaatcg tcagtaatcc
    49561 ggatgttccc tgatttggtt cgtcaggtgt aaaaggagta tcaggatcat ttggatcaac
    49621 aggaggaact ggaacaacgt cttcaggatt tgcagcatct ggtttggtca cagaaatcgt
    49681 tccttctgta gtggctgagc tcttattctc agcaaaaaca ctttgtgtac ataataatag
    49741 acttccagct agaacggtac ttaatgcaat tgtttttttc atttcttttt ccttctttct
    49801 tttaaaataa ataatccagc aaataagcca ataagaatga ctccaacaag tatcagccat
    49861 cgccagtcaa atgtttctgg ctgatttttt aaatcaatat ccttttcatt caattggtcc
    49921 gctgcatcat cagttatttc aaaatcggta tggagattcc agcgtttttc tttccaagca
    49981 cccttcacaa ccgcttgata atgtcccgga gctaattttt ttccttctaa tgggacaagt
    50041 aaatcaaaat ttgtattggg tgctacatct attttttctt tttttattga aaggtaaggc
    50101 tcttttgttt cttttttgta gatttcaacc gatgtagtca agccgaacat ataagaagca
    50161 tttggatttt gaagattcgc cttaatcaca tttcttccat cgctttgatc cgcataagct
    50221 ttttttaatt tcaaatctgg ggaagactct ttttcgctat ttcaaatcaa gattgctttc
    50281 acttgagaaa actgattgac gacaccaact gtacttttgt tagaaacgtt ctcttttttt
    50341 tcttgaaacg tgatccctcc tgcgaccaca ccagccagct ctttttctgg cgctttcagt
    50401 gaaagtgtct cagtgaccgc actttgagga ggaacagtta tttctcccac tgtttttgct
    50461 aagtttttca tatcataact taatgtttca tcaaatttac tttttgattc tccatattcg
    50521 atcacaccgt ttgaattcgt cgtagcggag tggatcaatg tctcaactgt tactgattta
    50581 tctgttcggt taaagaccgt gtaggggatt tcctgtgttt tcccaggctc catccttaca
    50641 tttatatatg ttttgttctt atcaatctga ttagccggta attcaaaatc taccgcaaaa
    50701 ttgaattcgg aggcatggac aggtgtctgc caaaggatga atccaaggag aaggatcata
    50761 agtaaagagc agttgtttcg atgactttta ttccatattc gattcatcaa tcatcctcct
    50821 tgatctttat tctgtcggcg catctgctaa tgtccatgtt atctctgctg agtaattacc
    50881 agctatctga ttttctttgg ttaagacaag tttaaacgcc cgaccgttat ttaaatattc
    50941 tgaataatct gcttgcacat tcgttgaatt ttgtcctctg acaatttcca gttcttcttc
    51001 attcactaat tgatactcct ctcctttctt gaaatatagg acatcctgca tagaaaatcc
    51061 tgcatcattt gtgaaaggct gagataattt tatcgttaag atccacggat ttttcgtttc
    51121 tcgctgatca taaatccata atttttcctg tatatccatt tggccaaatg cttcttgtgt
    51181 caaaccagtt gctttgatct gaccaaaatc gagtttggaa ggggcaagaa atgagagacc
    51241 accttctact acgatcttcg tagcaggtgc aaaaggcggg gcatcatgat aaacaactgg
    51301 cgtatcactt ggattgtgat tcccaatttc atcgttggta cttggcttgt tctgcacacc
    51361 cttagcagta gcttctcctg cttggtcgtt taatacaatt tctaatacat ctcctgcaaa
    51421 aagttgattt tctgggatag aaagaacaaa ttcccctgta tcatcaatag ttgtttctga
    51481 caaaacagct tgattttttt tcaatgaaac caaggctcct gcttcacctg tacctgtgat
    51541 cgtgcgagaa gctgcattga tcaatgtggt acttaaatta gcaggttcag gaggaatcac
    51601 atcgactgtc gttttggcag agtccagttc tgtcacttct tggccacctc ttactttttt
    51661 agcagcaaca acttgcactt gatcctccgt ttttaatctc tcatcattgg gtacttgaac
    51721 ttcgaacaag ccgccttgtt cgccttctcc ccatgggtta tatcctgccc cttcattttc
    51781 atctgtttgt ccttgcgtga gagcagtaat ttctacagat gatttcgtcg tatctgcgta
    51841 agtaatacgt aaagtcactt ctacttcgcc tgtccaagca tctcttggct ttgcctcgac
    51901 accttcggga acaacgacat gcccatagat ttttttatct gcattcgttg gcactcttaa
    51961 ggattcaatc atcgggagct gattattggc actgattcga ttataatttt tcattccggc
    52021 acctgtctga gcaaattcat ttgttaaacc tgcactaggg cttgatacga aattgcctaa
    52081 gtcggtccca ttgatcgata agtctgtcat atcagaaaaa taatccgggt ctttttcaaa
    52141 gttatcgaat gttgcgcctg tttttcgcca taaagcgatt tctgaatggg cgatctttaa
    52201 agaagaatct ccatttcctt ggaataccca gccgcctatg ccattggtct cgcttccaat
    52261 ccgtttgttt tggaaatcaa aataggtagg agattctaag tccacattca acacatcccc
    52321 actgatgatg ccggtcttat cttcccctgt tttcccgacc atgactaaat aagttttttc
    52381 acctgccgta aaatttaaat caatatctcc agttgtatct acagttgctc cggaatctgc
    52441 gcgtatatcg atatttgatt tttctccagt gactgtaaaa tcagctgaac ctggactttc
    52501 tagaaaacca gaagcgtcat aaaattggat cgcttgattt ccttgattga gtctgttcac
    52561 gtaagatttg ccatcacctg tatttcttac cctcaatgag cctccattgg ttactgtcag
    52621 cttttgcgta ccattctcaa aacgaactgc gctggaacgc ccactctgct tatcgatgtc
    52681 gataactgat ccggctcctt ctacgatcaa agaaaggcct tttcctacaa aacgcatccc
    52741 attgttcccg ggttgatcgt catctccagc cattttgacc gagatttgtc caccacttga
    52801 tacatggatt tgactagaat ctccttgcaa gcgaaatccg cccgtagttg ctgtattgat
    52861 ggtgattttc ccaccattcg atacagtgac tttcgatcct gaacctctca tttggatgat
    52921 tccgcgattg ttgtcattgg taatattgat ctttgtattt accgaaaatt cgcttcccga
    52981 accactgact tcaaacatga cattaccagg tagcgtatcg actgcctctc cttcatcgct
    53041 aacgccatct gcccgatcat aatcaagaga gacctttgaa ccgcttaaga tatggattcc
    53101 tggcgctgtt tttccactac cagtctcatc tcctgaatct agaaaaccgt agaatttccc
    53161 tagatacggt ccataaagtt gactaccatt gatcacattc aattgatagc ttctacaaaa
    53221 ataggcttta cccggagcgg cattcagtcc ttccttcact ggttggacat ccaacacacc
    53281 ggaaacacca tctaatgtga cagttgcacg aggagcgtaa atcagtccta atttggaccc
    53341 atcatacaaa tcaagtgtcc cggtaaattt tatttctccc gtaaaatgat atctgcttcc
    53401 ccaaaaatcg gtcatataag caatgataat ggcatttcca tcgatatttg gtgtcaatcc
    53461 acctggatgt gcagctgttc ctttaaaatt ctggaactcg atcgactgag gtatctcatt
    53521 gatataaata tggtgtgtgc cgaaattgtg agcgaatcca ccaaaatcaa taacgatatc
    53581 tcgtttgatc tctaattccc tgtctaaagt caaaggctga atcagtcgga tcttagttac
    53641 tgattcgtct gcgagaagct gcgccagttc ttctgttgtg gcagcttcgc tgtacccatc
    53701 cgctgaaaca gctcttgcca gtgccgcttc actgctatca gacgtttgtt cagctacttc
    53761 tgaggtctca cttgtcttat tttcttcttg ccttttatta gtagaagcct cactttgaga
    53821 ttctgtagtt tcagaagtaa tcgattcttc tgaaaaagta gtcttgtcaa aactttgatt
    53881 ctctgattgc gttgattcgt ttgttttctc tacatcggca aaaacggatg tcaccatcaa
    53941 gagagggaag acaaacaaaa tcgacgcaat cagctttttt acacattgat tcattctcca
    54001 ccatcctctc tgacgttttg acaattttat tttatcgttt taatctattt ccaattgtac
    54061 tttcatattt aaaatatgta tttttatgga aaaatttttc tattaggtgt aaatttcttt
    54121 tttgtacaaa aaaaaggctg tgacaaaagt cttgtcacag tcccttatcc cgaacaagcg
    54181 gtgttctccc gccaactcct cggtcacaac ctccatttta acaataaacc tgtaaatgtg
    54241 agggcaatac tttgattgtc acaggtaatt tatccccttc atctccatca acattcgtcg
    54301 tcaattcttc ctcatcagct aatgacacaa ctaattgctc acaagtaagg taggctagat
    54361 ttttcgtaga ttcatctact ccttttaata ggtctggcaa tgttttaagc gtatcgatca
    54421 aagaagaatc ttttaaataa accaaatgga gcttaccatc atccactttt gcatttggaa
    54481 gtaatgtttc aaaaccgccg actgagttag ttagtcctat cagcaaggta ctgctctcaa
    54541 tttcttcctt ctttccatca acttctacgt gaaacgagta ggattgtgtg gaagctaact
    54601 gtttgattcc tgacatgaaa taagctagtt ttccaaattt cgtcttcttc tccgcatcta
    54661 catcattgat tgattcaggg atagagccaa ttgcgacgac attcataaaa tagtcgtcat
    54721 ttatttttcc aatatccaat ggcttgactg attcaatcga aaaatgattg atcgcttcct
    54781 caggttctag cggtatccct aatgctcgag ccaagtcatt caccgtaccc aatgggaaaa
    54841 atccgaaatt tggccgatgt tcttgttcag cgattccact gattccttcg ttgactgttc
    54901 catctccgcc catgacaaac acactatgat acccttccgt agccgcttcg cgagtaaagt
    54961 tttttgcatc ccctgctttt tttgtatgca agacgaccac ttcatcaaac accgattcca
    55021 attttgctat cgctaattgc tcaaattcct ttgcttgttc accgcctgaa ctggggttta
    55081 ccactaataa aacttttttc atcactttct ttcccttctg attgatttct ttaatataac
    55141 gatagcataa agaaaaaaat taggctgtga tgaagtactg ttcatgaaac attcatttat
    55201 tttttgacaa gataaaacat ccatactatg aaactgagga aaattaaaac aatgatatag
    55261 gaaataaaag aaaatgatag gcattgtata cctaataaag taaaaatctt aggtggcaga
    55321 taaaaacaca aaaatagcaa gagaatgtaa tagcgtttct tccacttttt gttatcagac
    55381 cttatagcga tcagaggaat accaaatgca taactgaaaa actcttgatg tactgttaat
    55441 atgtcacggc cttgaataat aaatgcgaca atccccgcta taattagtgt gcctaacacc
    55501 aaaacggaaa attgatgaat atattttata tacaaatgat ccattgtact tcctgccttt
    55561 ttatttgtga gaaaaacaaa tccgtatacg tgaataactt ctagaaataa
//
LOCUS       DAZAOD010000009        53868 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000009 DAZAOD010000000
VERSION     DAZAOD010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.009"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(18..245)
                     /locus_tag="ACHDPO_000600"
     CDS             complement(18..245)
                     /locus_tag="ACHDPO_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFN3368257.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(242..760)
                     /gene="msrA"
                     /locus_tag="ACHDPO_000601"
     CDS             complement(242..760)
                     /gene="msrA"
                     /locus_tag="ACHDPO_000601"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFN3368258.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(780..1493)
                     /locus_tag="ACHDPO_000602"
     CDS             complement(780..1493)
                     /locus_tag="ACHDPO_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFN3368259.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(1496..2392)
                     /locus_tag="ACHDPO_000603"
     CDS             complement(1496..2392)
                     /locus_tag="ACHDPO_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFN3368260.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(2550..3392)
                     /locus_tag="ACHDPO_000604"
     CDS             complement(2550..3392)
                     /locus_tag="ACHDPO_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFN3368261.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            3524..4177
                     /locus_tag="ACHDPO_000605"
     CDS             3524..4177
                     /locus_tag="ACHDPO_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFN3368262.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(4240..4767)
                     /locus_tag="ACHDPO_000606"
     CDS             complement(4240..4767)
                     /locus_tag="ACHDPO_000606"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFN3368263.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(4787..5734)
                     /locus_tag="ACHDPO_000607"
     CDS             complement(4787..5734)
                     /locus_tag="ACHDPO_000607"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFN3368264.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(5746..7629)
                     /locus_tag="ACHDPO_000608"
     CDS             complement(5746..7629)
                     /locus_tag="ACHDPO_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFN3368265.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            complement(7792..9870)
                     /locus_tag="ACHDPO_000609"
     CDS             complement(7792..9870)
                     /locus_tag="ACHDPO_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFN3368266.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(9883..10158)
                     /locus_tag="ACHDPO_000610"
     CDS             complement(9883..10158)
                     /locus_tag="ACHDPO_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368267.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(10520..10975)
                     /locus_tag="ACHDPO_000611"
     CDS             complement(10520..10975)
                     /locus_tag="ACHDPO_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368268.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(11129..12337)
                     /locus_tag="ACHDPO_000612"
     CDS             complement(11129..12337)
                     /locus_tag="ACHDPO_000612"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFN3368269.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(12449..12781)
                     /locus_tag="ACHDPO_000613"
     CDS             complement(12449..12781)
                     /locus_tag="ACHDPO_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFN3368270.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            12929..13804
                     /locus_tag="ACHDPO_000614"
     CDS             12929..13804
                     /locus_tag="ACHDPO_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFN3368271.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(13886..14467)
                     /locus_tag="ACHDPO_000615"
     CDS             complement(13886..14467)
                     /locus_tag="ACHDPO_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFN3368272.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(14473..15732)
                     /locus_tag="ACHDPO_000616"
     CDS             complement(14473..15732)
                     /locus_tag="ACHDPO_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFN3368273.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(15734..16780)
                     /locus_tag="ACHDPO_000617"
     CDS             complement(15734..16780)
                     /locus_tag="ACHDPO_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368274.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(17015..17290)
                     /locus_tag="ACHDPO_000618"
     CDS             complement(17015..17290)
                     /locus_tag="ACHDPO_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFN3368275.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(17533..18843)
                     /gene="der"
                     /locus_tag="ACHDPO_000619"
     CDS             complement(17533..18843)
                     /gene="der"
                     /locus_tag="ACHDPO_000619"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFN3368276.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(19025..20254)
                     /gene="rpsA"
                     /locus_tag="ACHDPO_000620"
     CDS             complement(19025..20254)
                     /gene="rpsA"
                     /locus_tag="ACHDPO_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFN3368277.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(20389..21069)
                     /gene="cmk"
                     /locus_tag="ACHDPO_000621"
     CDS             complement(20389..21069)
                     /gene="cmk"
                     /locus_tag="ACHDPO_000621"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFN3368278.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(21118..21753)
                     /locus_tag="ACHDPO_000622"
     CDS             complement(21118..21753)
                     /locus_tag="ACHDPO_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFN3368279.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(21819..23222)
                     /locus_tag="ACHDPO_000623"
     CDS             complement(21819..23222)
                     /locus_tag="ACHDPO_000623"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFN3368280.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(23209..24240)
                     /locus_tag="ACHDPO_000624"
     CDS             complement(23209..24240)
                     /locus_tag="ACHDPO_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3368281.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            24271..24492
                     /locus_tag="ACHDPO_000625"
     CDS             24271..24492
                     /locus_tag="ACHDPO_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFN3368282.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(24657..25394)
                     /locus_tag="ACHDPO_000626"
     CDS             complement(24657..25394)
                     /locus_tag="ACHDPO_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFN3368283.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(25547..26887)
                     /locus_tag="ACHDPO_000627"
     CDS             complement(25547..26887)
                     /locus_tag="ACHDPO_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFN3368284.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(27124..28647)
                     /locus_tag="ACHDPO_000628"
     CDS             complement(27124..28647)
                     /locus_tag="ACHDPO_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFN3368285.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(29025..29636)
                     /locus_tag="ACHDPO_000629"
     CDS             complement(29025..29636)
                     /locus_tag="ACHDPO_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFN3368286.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(29759..29884)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(29966..30682)
                     /locus_tag="ACHDPO_000630"
     CDS             complement(29966..30682)
                     /locus_tag="ACHDPO_000630"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFN3368287.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(30688..31257)
                     /gene="scpB"
                     /locus_tag="ACHDPO_000631"
     CDS             complement(30688..31257)
                     /gene="scpB"
                     /locus_tag="ACHDPO_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFN3368288.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(31241..32011)
                     /locus_tag="ACHDPO_000632"
     CDS             complement(31241..32011)
                     /locus_tag="ACHDPO_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFN3368289.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(32008..32379)
                     /locus_tag="ACHDPO_000633"
     CDS             complement(32008..32379)
                     /locus_tag="ACHDPO_000633"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368290.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(32398..33285)
                     /gene="xerD"
                     /locus_tag="ACHDPO_000634"
     CDS             complement(32398..33285)
                     /gene="xerD"
                     /locus_tag="ACHDPO_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFN3368291.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(33381..33854)
                     /locus_tag="ACHDPO_000635"
     CDS             complement(33381..33854)
                     /locus_tag="ACHDPO_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFN3368292.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(33959..34822)
                     /locus_tag="ACHDPO_000636"
     CDS             complement(33959..34822)
                     /locus_tag="ACHDPO_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFN3368293.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(35018..37117)
                     /locus_tag="ACHDPO_000637"
     CDS             complement(35018..37117)
                     /locus_tag="ACHDPO_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFN3368294.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(37337..38446)
                     /gene="rpoD"
                     /locus_tag="ACHDPO_000638"
     CDS             complement(37337..38446)
                     /gene="rpoD"
                     /locus_tag="ACHDPO_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFN3368295.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(38470..40311)
                     /gene="dnaG"
                     /locus_tag="ACHDPO_000639"
     CDS             complement(38470..40311)
                     /gene="dnaG"
                     /locus_tag="ACHDPO_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFN3368296.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(40493..42808)
                     /locus_tag="ACHDPO_000640"
     CDS             complement(40493..42808)
                     /locus_tag="ACHDPO_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFN3368297.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(42993..43853)
                     /locus_tag="ACHDPO_000641"
     CDS             complement(42993..43853)
                     /locus_tag="ACHDPO_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFN3368298.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(43912..44544)
                     /locus_tag="ACHDPO_000642"
                     /pseudo
     CDS             complement(43912..44544)
                     /locus_tag="ACHDPO_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            44711..45472
                     /locus_tag="ACHDPO_000643"
     CDS             44711..45472
                     /locus_tag="ACHDPO_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFN3368299.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            45498..48089
                     /gene="mprF"
                     /locus_tag="ACHDPO_000644"
     CDS             45498..48089
                     /gene="mprF"
                     /locus_tag="ACHDPO_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFN3368300.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(48277..49464)
                     /gene="tuf"
                     /locus_tag="ACHDPO_000645"
     CDS             complement(48277..49464)
                     /gene="tuf"
                     /locus_tag="ACHDPO_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFN3368301.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            49832..50188
                     /locus_tag="ACHDPO_000646"
     CDS             49832..50188
                     /locus_tag="ACHDPO_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFN3368302.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(50429..51433)
                     /locus_tag="ACHDPO_000647"
     CDS             complement(50429..51433)
                     /locus_tag="ACHDPO_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFN3368303.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            51599..52450
                     /locus_tag="ACHDPO_000648"
     CDS             51599..52450
                     /locus_tag="ACHDPO_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFN3368304.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            52467..52712
                     /locus_tag="ACHDPO_000649"
     CDS             52467..52712
                     /locus_tag="ACHDPO_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368305.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            52899..53603
                     /locus_tag="ACHDPO_000650"
     CDS             52899..53603
                     /locus_tag="ACHDPO_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368306.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT        15114 a        11267 c         9250 g        18237 t
ORIGIN      
        1 aagtacaaaa ctatctctta tatgtcatga ttattttcta aatatttttc ccatgcttcg
       61 tcaaagatat ccatggacgg caaatagtcg acattcagtt ccagataatt agaaatttct
      121 tcgtagctag agctgtgctt aggaaattgg atgtctttac cggcttctgt agcgaaaaca
      181 gataaagcat catgtgtgcc accgcctcgc agtgtcatta aataatgaaa aaagcttcga
      241 ttcacccttc gttcctccaa ttttcttcga taaaggcagc ccggcgtgca tggtttcttt
      301 taaaattttc aggatgcttt ttataatact cttgatggtc ttcttctgct agataaaatg
      361 gttgggctgg ttcgattttt gtaacgattg gctgttcgaa acgtccactt tcagctaact
      421 gtttcttact tttttcagca atgatccgct gttcttctgt caaataaaag atcaccgggc
      481 gataattgtc accgcgatcc tcgaattgtc cgaaagcgtc agttggatca gtttgctgcc
      541 agtaaagttc tactaattgt tcatatgaaa tcaatgttgg atcatagata atctccactg
      601 cttctgtatg tccagtcgtt tggcttttta cttgttcata agtcggatct ggtacatgcc
      661 ctccagtata tcctgacatc actgtatgga taccaggaag cgtgtcgaaa ggctggatca
      721 tacaccagaa gcagcctcct gcaaatattg ctcgttccat tatgattccc cctctaatac
      781 tactcatccg atgatttttt attttctttt gtcttgcttt cagtactgct ggtgctagtt
      841 ttgttggtat ttgagttgtt tgaagcatca gaggtatctt ttggcaaata tagactaaac
      901 cgaatgtcat catttactaa gtcgatttta tctgctttaa tatacatccc gttttgcatt
      961 cggaattgat ccaacctaag catgatagtc agatcatctg tattgacttc gatccaatct
     1021 ggtaatttat agtttctctt gatcatattc atcacatctt tgattggcaa actcaatgtt
     1081 ccgatagaaa gacttctagc ttttagttgg acatttccgt tttccatcac atacggatca
     1141 aaatataaat agaaatcgat aggaaaacct agtacttcga aagtaccatt gagtagtgct
     1201 tcattttcca aataaaattt atattcaata tcactatctt tttgatactc actaaggaaa
     1261 aagctgatga tttgattgac tttttcttta tttgaattga tcgttaagac aggatctcct
     1321 tgtctttccg taagagctgg tatttctggg agttctggtt cccgattagc aaaaatacgg
     1381 ctgcctaaaa atacggtcga accaagtact accccaagaa ggataaggaa ggcgaatttc
     1441 cagtaatttg ttttctttgt tttgtttgaa gatacgtcag atcttgtttt catgtttatt
     1501 gatcatcctc cttctctaac cattggtttt gtgtctcgat cagctgatct ctcactgcat
     1561 ttgccatcaa ttgataacct aaattatttg gatggaaatg atcttcttca tagagcacat
     1621 tatttttgat gccatttaga ttttctgtcg tgctagttgt ttgatctgtt ccttcttctg
     1681 tgacacctac ttcctgattc aatccttgat aaagcaaatc attgattggg ataaagtagc
     1741 agttcggcat tttttttgtc accgtttctg ttcctttgtt ccaattgtta acaattgtct
     1801 gcatgtcagt gatctcagga aagttcaaat aaaatggatt gtagatgcct aaaatgtaaa
     1861 taggtgcggt tttattgagg gatcgaaatt cttccaatag ttctgtgaca ttttcctgat
     1921 agtttttcag tggcttttta aaggaattga ccgttaaccc gaataaatta ttttggataa
     1981 ctttcatcaa atcattaccg ccaacagtca gtgtgataaa atcagctgtt ttgatattgt
     2041 ttcgaatttc ttcttttgtt tttactcgct ttaagatctg gtcacttcgt tcaccattta
     2101 caccatagtt ttctgtttca accgcggtca aattataacg gtcttttaga tcatttgcga
     2161 caaggggaac gaatcctcct tgcttggttt gatctcctac tccttcagtc agcgaatctc
     2221 cgatagctat gtagtgaagt ttttcttttt tatttggatc ttctctcaca gtagttactg
     2281 gtttcattag tgggccagct ttcggtatag aagcagctaa acctgcatag atgatgatcg
     2341 caattaataa tgggaacaaa acgaggatca aatgtcgttt cgttaatttc attttttcac
     2401 ctcttgtatt cgattggttc taatgttatc aaaaatttta tcaaaaaggt agtctttatg
     2461 aaaaaagaaa acaattattt tcctaatttt ataaagaaaa agagaataag ctgcaagcct
     2521 ttcaggctga gggcttatcc tcttttcgac taatctacat aatacatgat tgcaaacgcg
     2581 tctttaccag tatgcgtagc gataaccgga ttcgtatgca gtacagggat atgcatgtcc
     2641 gggaataatt cttgcaaacc ctctttgaat tcttgcgcca attcttttgc atccgcatgt
     2701 gaaataccga tttgtcgcac atttggcaat tctttcagtt catttttcaa attattaaac
     2761 catttatcga acgttttctt tcctcgcccc ttagttacag ggattaattc agaatgggcg
     2821 aaattcatca ccacgcgtat gttcaaaaca ctagacagca aaccagttgt tcggctgatt
     2881 cttccacctt ttaccaagtt atctagtgtg gatattccga tgtataattt tgtattgtct
     2941 tgtacttttt tgacttcttc aaggattttc tctactgttt taccttcttt tgctaattca
     3001 gctgctcgaa ttacctgaaa agataatcct tggtcagtgg tatcactgtc gataaccgtt
     3061 actttcgttt ttgttagatt actggcttgt cttgctgctt ctactgttcc actcaagcct
     3121 tttgtcatat ggatcgaaat cacttcactg ccgtcttctc ctagctcatc atacatcgag
     3181 atgaattctc caattggtgg ttggcttgtt ttgggcagat tttttgcttt cgccatcatt
     3241 tccataaatc tttcgccgtc tagttggtca tcatcgggat atactgttcc gtcgatcatg
     3301 atggatagcg gcatgacacg aatgcctaaa gcatcgcgta catttttttc catcgtacat
     3361 gaagaatctg ttacgatttt tacatttgtc attattttct ctctctcttt ctttaacaag
     3421 atgccttatt catgttaaac tacatgtaag acaatttcta tttttagtat aacagacaaa
     3481 taatgatttt tcattaatta cacctagtaa aggagccgtt ttcatggaaa aaacgaaatt
     3541 taatcgaacg tatgaaatat taaatgaagt gtttaatgca gtcacccatg gaattgggac
     3601 tggattgagt atcgcgggac tagtggttct tttagtaaaa ggtgcccact tgcattcctc
     3661 cctccatatt gtctcttatg ctatctatgg atcgatgatg attcttttat ttttaacgtc
     3721 tactttgttt cattcattga tttttacaaa agcaaaaaag gtgttccaag tattcgatca
     3781 tagttcgatt tttcttttga ttgcaggaag ttatactcct ttttgtttgc tgagtatccg
     3841 aggatggcta ggttggactt tatttgtatt aatctggttg tttgcgattc ttggcattat
     3901 atataaagcg ttgacgttgc ataaacggga gagagtatca aaagtatcta cgatcatcta
     3961 tatttttatg gggtggctct gtgtcgtggc tgctgttcct ctttatcact ctcttggaat
     4021 gactggtgtt attttgatgg tagcaggcgg gctttcttac acgataggcg cattctttta
     4081 tagcttgaat tctatccgct atatgcatgt tgtttggcat ttgtttgtta tgttaggtgc
     4141 aggttttatg tacttctctg ttttattctt tacttaataa aaaaaataaa gctatggatg
     4201 ggacagctct aaataacagc tagtctatcc atagcttttt tatatcgtca attcgcctgt
     4261 cccgcttttt acaggattct cattacgctg atacgtttca aattgatgcg gataacgatt
     4321 tttttcatcc atttctcctt gactagtatt gatcagtgac caatcagacc agtcaacagg
     4381 tggaaaataa gcatctccat cgaatacatg atggatgact gtacggtata atatcgtaca
     4441 aaatggcaga aattcttgat aaacagctga ccctccagcg atgaaaaaga taccgtctgt
     4501 ttctttttcc agagcaagca cgtcttccac actatgcatg acatgcacgc cttctgcttt
     4561 ataggaagaa tctctcgtca aaacaatcgt ctgacgattc ggcaacggac ggctacccat
     4621 cccttcgaat gtttttcgtc ccatcactag tgtatttgct tctgtcattt gtttgaagaa
     4681 tttcagatca tttggcaaac gccaaggaag acggtcttct tttccaatca atccgttttc
     4741 atcctgtgcc caaattgcag ctaacatttt ctcatccttt ctgattctaa acagcgatag
     4801 gagctttgat cgccggatgt gggtcatatc cttctaattg gatatcttcc atctcaaaat
     4861 caaatactga ctgcttttcc tgattcaaaa ctaaagtcgg aaatgcgcgt atttctcggc
     4921 tcaattgttc tttcatttgt tcgatatgat tgatataaag atgagcatct cctaatgtgt
     4981 gaacaaattc gccaaccgct aaacctgttt catgtgcaat taggtgagtc agcaacgcat
     5041 aacttgcaat gttgaacgga acgcctagaa acacatcccc actgcgttga tacaattggc
     5101 agcttagccg tccctcttga acataaaatt gaaacatcgt atgacaagga ggcaaagcca
     5161 tgctaggaac atcttccgga ttccatgcag aaacgatcaa tcttctagaa tcaggagtct
     5221 ttttgattgc ttcgatcact tgtttgattt gatcgataaa gccaccgtct tttgtttccc
     5281 agtgacgcca ttgatagccg tagatgtgtc caagatcgcc gtatgtttca gcaaaggaat
     5341 catcggttag gatcttctcg caaaaaagct tgctctgctt tttatattct tcattgaatt
     5401 caggatctgt caaacatcta tggccaaaat cagtcatatc tggtccatta tagtctggac
     5461 ttttgatgta gcgttcaaat gcccattcat cccaaatatg gtttttattt tgtaatagat
     5521 agcggatatt cgtatctcct tttaaaaacc aaagcaattc gcttttgatc aatccaaaag
     5581 gtactcgttt cgttgttaac aaaggaaacc ctttttgcag atcaaaccgc atttggtatc
     5641 cgaataagct taatgtgcct gtgcctgttc tgtcttcttt acgatgccct tcttccaaca
     5701 attttcttcc taagtcaaga tacgcttgtt ccatcctttt tcctcctaat cttctaccca
     5761 ttcactcaag tattcccacc gtgccatttt ttcttcaagt tgtgcttctg tttcagatac
     5821 gtcgttttgc aattcttgta atcgagtgaa attatctcct tgatgattca tctcttcttg
     5881 gagcaatgag attttttctt caagttctgc aatctcatct tcaatcgttt cccattcttt
     5941 ttgttccatg taagataatt tcttcttttc agcaggttcc ttgctctgta tttttggttt
     6001 cgctttttca gcaggctgct gggtctcttt ttgcttcagt aaataactgg acatgtttcc
     6061 gtaataaagt tcttgttttc cgtttccttg gaatactaat aacttatctg ctaccttgtc
     6121 caagaaataa cggtcatggg aaacagtgat cacagcacct ggaaaacttc taaaataatc
     6181 ttccaaaatc gtcaatgttg ctatgtccaa atcattggtc ggttcatcca ataataaaac
     6241 attaggttgc tgaatcagca gtttcaacaa aaataaccgg cgtttttctc cgcctgaaag
     6301 tttgcctatc agtgtcccat gcataaatct tggaaataaa aatcgttcaa gtaattctgc
     6361 tactccgatt tgactgccat ctgctgtttt tgcttcttca gcagcttctt gtaagtaagc
     6421 aatcatccgt ttatctggtg ccatttcttc attttcttgt gtataatacg caagatgaac
     6481 cgtttcaccg atagacattg taccgctatc caggggaatt ctgccagcta gaatattaag
     6541 caatgtcgat tttcccgcac catttttacc agtaatacct agtctttccc gagattgaat
     6601 caataaatct aaatgttcta gcagtgtttg gtcatttata cggtaactgc catctttgat
     6661 ttccagtact tttttcccta aacgttgtgt cgctaggttc agctctaaat catcttcttg
     6721 gtttacttgg tacaagttct cctttagatc ttcgaaacgg ttgatccgtg cttgctgctt
     6781 ggtgccacgt gcctgtacgc cagccctcat ccaagctaat tcctgtttat aaagccgctt
     6841 gcgcttttct tcttgttcta cttctacacg atcacgttct gctttttcta agacgtaagc
     6901 ttcataattt cctttatact cgtataattt tccaaatgaa agttcgaaga ttcggtttgc
     6961 tactctatct agaaaataac gatcgtgggt aaccatcaat agtgcgccac ggtattgttt
     7021 caaatagttt tccaaccact cgatcgcttc ataatctaaa tggtttgttg gttcgtctag
     7081 taatagtaaa tcgggttcat caatcaacac ttgcgccaga ctaactcgtt ttttctgacc
     7141 acctgataaa gtactgattt ttttatctaa ttcactgatt cctaattttt gcaaaataat
     7201 ctttgcgttg gtatctgtag tccaagcatc ttctttattc atttgttctt ctgctttagc
     7261 ataacgtttt tgcacatcag ggtcttctcc gttttcccct agttcgatca atgcttcctc
     7321 atatgctcga acagtttgga tcaaggggct gtttccttga aagactgctt ggagaacagt
     7381 taattcatcg gaaaattcag ctgcttgaga aagataacca atacggtaat cagttggata
     7441 aaacactgtt tgccgatcac cgtcgctgct atcgataccg gcaataatat ttaagagact
     7501 tgttttaccc gtcccgttcg tcccaatcaa cccgatacgg tctttttcgt ggaccaaaaa
     7561 agaaatctgg tcaaacaaat ctttttcacc ataagttttt ttgaggtcag ttacttttaa
     7621 ttctttcaac atgttccctc cttatcttgg atattgtatc ataaaaatag tgaacttcag
     7681 gaaaattttt ttggtatttg ttctttttgt gttctcaaaa aaagaacagg accgattcga
     7741 tcctgttctg atatgttttg ttttttataa aacttgaaaa tttttacctt tttattttat
     7801 tggactcgtt ttttttgact ttgctcgaaa cgcaaatcgg aaagaaaagt tatcagatgg
     7861 tttgttcatc gtataagatt ctaacaaatt gatattcctg cgatagctgt tcgcagaaaa
     7921 cgtcgtgatt ttttcagcaa cttcgtattc atcaatgatt tttctttcaa gataataacc
     7981 tcttagcatt tttttcgtaa acagactatc ttgctggatc atccacgaag aaatcaaatt
     8041 ccccgagttc atttttattc cttcaagttt gcgttgctgg ataaaaaatt gaaccatcgt
     8101 ttcatcataa atatcagtca agttatctaa actttcaata atcaactgag tatttttttg
     8161 atatgtctct ctgatttctt ggatatcttc atcactaata aatgtctgac gatcagcata
     8221 tcttctttgc caaaacattt tcggatggag aacgattcgc attaacctac ggacaacaat
     8281 gaaccaaaag ccgataaaag acaaaatctg gcttgtgata gaatgttcga atcgagaaag
     8341 aaaacgggag taaaaacgat aaccattaga agaaagcttg cccgaacgat aactttcatc
     8401 caatccatcc cgttcgatcg acaaaatcag tgcttgtatt tcttgtactt cttgcttttc
     8461 atcatcggtt aaatcttcca agtacagatc acgtatccgt tcttgataat tttctatcac
     8521 tgcttcagtg gctaaaaatt cttttgtatt acgatcaatt tcctttattt cttttcgcaa
     8581 aacttcaacg acctcttcta aaatcatcaa agcattcaaa tccgtgcttt tcgcttcctc
     8641 tgtttccgtc agcataggca agacaatgat ccctatgacc aaagtcacta agatgacacc
     8701 cgccgtcaga aacaaaagca aagaccgctg gtaaaacatc atattattga ttgaaaatgg
     8761 caaaataaaa atcgtagcca aactgactgt tccctttaca ccgccaaatg ttaagatcaa
     8821 gatctcgttc aactgttttt tgaacttttt actgccatct ttgaatacat aaaaaagact
     8881 gatagaaatg aatctgatca caaaaagcat gacagagatt aatacgataa tcgctaataa
     8941 aagaccgttt ggatataaac cgtctcccca tactggcgag aacacttgcg tcaattcgat
     9001 tcctaaaaat ataaatacta atgcattcag tgtaaaagca atagttgtcc atgtactgtg
     9061 ggacaagctc gacaattctg catcaaacac agagattttc ctaaaaccag aagcttggag
     9121 aatacctgct gccactgcag caatgattcc agatacatca aatgcctctg ccaatacata
     9181 ggctagaaaa ggaagcaaaa gttcgatcag cagataccct gtgacatctt gtgctgatgc
     9241 tttttcgatc aaatgaatta ttttttgttt gaaccagaca agcaaaaagc cgatcaaagc
     9301 tcccccaata ctagaaacta ctagactcat ccccgcgttt actgctgaaa aagatccggt
     9361 gatcagcgca ccaagagcaa actggaaggc agtaacacca gatgcatcat tcaaaagacc
     9421 ttctccttcc aaaatatgca tcgccttttt agggatattc actcgtccag aaagagaact
     9481 gactgctacc gcatctgtcg gacctaacgc tgctccaaaa gcaaagcagg cagcaagtgg
     9541 gacacttggc aacaggaatg ataacgtcgc acctaccccg acaagggtca aaatgactcc
     9601 tccaaatgcc aagaacaaaa ttgtcccgaa atttttgaga atcgaagaaa tatctgcttt
     9661 ttctccttct ctaaataaca atggtgcaat aatcataact aagaacaatt caggttcaaa
     9721 atcgattgat tgtccccact ctgtcagacc taataccact ccaaggaaaa tttggatcag
     9781 tggagctgga atcattggca aaatgcggct agctatgttc gataaggtga tcgttactgc
     9841 aaatacaata actaactcag caaattccat cgtccatccc ctttattttt tattttgtgt
     9901 aagcattttt aaaaattgtt cttttttctt taaaattttg gtttcgacta cttcaacctg
     9961 tgtttggttc ccctctaatt cacactgtac acgttttgac tccaaacgaa gcagatcatg
    10021 tttcagacgt tccaactgac gatacatcaa tatatttctt ttacgcaact tacaaagtat
    10081 ttgacggcgg tcatccatcg aaagggcgcc atagcgatca tgcaacagtt ttttttgttg
    10141 ttcaaaactc tctctcattt tccagatctc ctatacacaa acttccatca ttatagcaaa
    10201 gttctttttg gatgaaaaat atttcattgt ttcatcgttt attgctagtt agaaatttcc
    10261 ataaattttt caacgcctca ttctattcca aatagtatca gatatcaagt aaaacttaag
    10321 aaagataaaa gtttctgaca aaaggatgtt tactttccca ttcctgcctt tcttgttctt
    10381 ttatcacaac aaaaaaatgg ggctgcgaca aaaatcttgt cacagtccct tattctgaat
    10441 aaacggtgtg gaagagacag cctatcagta gtaataagac acatctcttt cacagcctca
    10501 tttttgcgta aaaatcgatt tattcgaaaa attccccgta tacatcttct acacgttgat
    10561 ctggattgat cacgatatac aagttacctg ttttttcgct gatttttgtt gattgatatt
    10621 gattgtctaa tccttctgtt cctttatcta gatatgggaa gtacacaaga tcaggtgtgc
    10681 catttcggta aaggatttcc attcgctcga tatcttcgta tttcaatgcg cgattaaaca
    10741 tgcccatttc cagtccgcct aggttgatat catgtgtcgc aactgcgtcc ccttcatgga
    10801 agatttcgat tttaaatcca gcacacggat ggatttcaac aaattcactg ccattgattc
    10861 gtccaaaact tgttgtgatt tgtttgatcc aaagatcgcc gatatgacgg cggttgatcg
    10921 tccaggtttc tccatttcta aaataaaatt ttagcgctgt catttcttta ctcattaaaa
    10981 agactccttt atgatgtaat ttattcttgt actacctcag tttagcacaa atttatgtaa
    11041 gtggtcacat cttatgtttt ttcttctaat gacgtatctg cccactttaa gtagccaaca
    11101 aagctgagca gatacagtct agtgtttttt aaatcaattt ttctttcgat aaaaaatcca
    11161 aaacctgttt tttatcattt tttattcttt gttctacgac ggctttttca gctaattgca
    11221 aagcttcact aacccactta ccaggttttt ttccagtttc ttctagcaag attttaccat
    11281 ctactgctaa ttcgcttaat gacttgatag gtaaacgatc ataggattct cctacggcat
    11341 ccatctgagg tgtttcgtca aaatagatca tcaattcttc tacttgcagt gcatgttttt
    11401 tgcctaagaa gtacaattcg aatggttcca aagctccagt ttctcgttgt cgtagtcctt
    11461 ggacaagtgc ttgaacgtct ttaatcattt ggttagaaca cttccacgat ttcaaaaagg
    11521 aacgaatctc attttctttt agatccagtt ggctgatcaa taatgcccat gcttggctct
    11581 cttctttcaa tgggacggat ggtaattcag caaaacgtaa aagtgcttcg ccttcttctt
    11641 tcaaaccggg acagcaaatg tagcactctg tttcaataaa tgcatggatt cccgcggccc
    11701 gttcatttcc caagagcatc ttgatgaatt ccacatttat acgttctaca gatattttac
    11761 ctaatagctc gtggttttct ttgatggcgt agaaggtttc ttcctctaat ttgaacccta
    11821 gttgactgac aaaacgcaac ccgcgcatca ttcgtaaggc atcttcatgg aaccgctcat
    11881 gaggattgcc tacagctcgc aagatctgtt cttctagatc ttgcagacca tcgaacaaat
    11941 cgatgatttc tccatcttct ttcaaagcaa acgcattgat cgtaaaatct cttcttttca
    12001 aatcttctgc caacgaacga acgaattcga catgatctgg tctacggtag tcctgataag
    12061 ttgattccgt ccgaaatgtg gtgatctcat attgttcatc attttctaat accaacacag
    12121 ttccatgttc gatcccaata tctatcgttt ttggaaaaag ctgtttgatt tcttctggaa
    12181 atgcgcttgt tgcgatatcc acatcatgga ttggctggtt cagcaagata tcacgaacac
    12241 ttccacctac aaaataagct tcatatcctg cattctctaa ttttttcaga actggaattg
    12301 ccttttggta ttccagaggt aattgtttta atttcatttt tccaaccttt cctgcgtgtt
    12361 tcttgtcctg agataaagac tcagttgcat ggtgactgtt tgacaagtcc gtttcagagt
    12421 cttcaaggcc aggaccactt catcttgttt actcgtcctt acgctcaaag cgattatggt
    12481 ctctttgatt gaatttttcc atgttttttt caaaaacttc agttaagtcg atattcaatg
    12541 aattagccat gatcatcgta acgaataaaa catcaccaag ttcttctgct accgagttaa
    12601 ctggttcaga agcctttttg cttttttctc cataagtgtg gttgacttct cttgccaatt
    12661 cacctacttc ttcagttaat cgagccatct gagctaatgg agagaaatac cccaccttga
    12721 attgctggat atattcatcc acttcctgct gcatactgta taaagaacgc tttttatcca
    12781 tctttttccc tccaaaacta tcttaccaaa actttaacgc aaatcctaga taagagcaat
    12841 tgagaaaatc gaatttccat gctacattta ggaaggaatt tctaaatgga aattctgtga
    12901 aaatacataa ttgaaagctg gaattcatat ggtcaaacga aaaacagtaa aagaagttct
    12961 ttttatcatt ataggaacaa gtatttatgc atttggtctt gtttacttga acatcgctaa
    13021 tcatttagca gaagggggag tctcagggat caccttgatc ttaagagctt tatttggtat
    13081 tgatccagct tatacgactt tattaatcaa catcccattg attttactag gaggaaagat
    13141 cctcggtaaa cgttccttgg cctatactgt tctaggtaca ctttctttgt cattcttttt
    13201 atggatctgg caaagggttc cactagaaat caatttacag catgatctac tgatcgtttc
    13261 tctacttgcg ggtttagttg caggtgtagg aagcgggatc gtctaccgca tgggtggaac
    13321 aacaggcggc agtgatatta tcgctcggat tttagaacaa aattacggca tcactatggg
    13381 gcgttcccta ttggcatttg atatcatcgt cttacttgct tcattaacct atatcgactt
    13441 gaaacgtatg atgtatacgt tgattgtttc gtatgttttc agtcgtgtga ttgattcgat
    13501 cttagatggc ggatattctg caaaaggtct acttgtcgtc tccaacaaaa gcgaagagat
    13561 tgcaccacta ctgatgaccg gtctgcaaag aggtgtgact ttcctttctg gagaaggcgc
    13621 attctctggt aattcaaaaa aaatcatcta tatggtcgtt agctctagtg aattaactga
    13681 agctaagagg atcgtccacg agattgacga aaaagctttc ctttcaatca tcaatgtgca
    13741 tgaagtggaa gggcaaggct ttacttattt gaagccacag acaagattac tgaaaaaact
    13801 ataagaaaaa agacaaagat aggctatgag gaaagattcc acatccagct gacctttgtc
    13861 ttttttagta ctatactatt tttaactaat tgttatgttc acttacccgg ttacttttct
    13921 tttgtgtctg caaaaggatc tttcggttaa cttcatcaga taatttcaaa aaagcatccc
    13981 tatctccatc ttctagtgct tgatcgattt gagcataaag catttttagt tttgcctctt
    14041 cttctttttc ttgaaaatat cgttcaatta attcagtatc ttcttcactg actgaagaat
    14101 cccaagaaga aaatggattg tcttctaaga tagatagata ttctcttgtc tgccaagcat
    14161 tttcgaatat acattccaca tataaaggct ttttccaatt caaacggatt tcatgaaaaa
    14221 tctggtctgt gtccgtaaat tcttttccct gcaaaaacaa tttcatgggt tccccttcaa
    14281 cagatagatc actgatctgc agtcctcgat ccgcaaaatt cgccccttca acaaagtgga
    14341 cattgcttaa aatcgcttca tgattggcaa gataattcaa gatccaaaaa acttctcttc
    14401 ggctaaaaga tacatgattg accatccacg ttaaaaaatt cttcttttcc cgtacatcaa
    14461 ttagcatttt tctcacctct ctgttaggtc atctaataat gacagtgcct ccatatctcc
    14521 tggttcaagt gttaaataat aagtcaataa ttcttgcgct cttttcagct gcccttcttc
    14581 tcttaagaaa aaggcatact ctttcaagaa atctggttca tgtgatagtt catgataagc
    14641 ctgttcatag tgtacagctg caacggtaaa gtcttctaat tcattataag catgggctag
    14701 gttccattct gcataaggat tagcagtttc ttccatctga ttgatcactt gtatcacatc
    14761 ttcatatctt tcatcatcca agtaaagatt acttaaagta agtaatgttt catcttgttt
    14821 gtctcctact tctaaagctt tcagtaaaag ttcttctgct cgctgtctat catgcagacg
    14881 gaaagcattt tccgaggcca ggtgataaag ttcgacttgg taaggatttt ctttgattcc
    14941 ttcttctaac actgtttgtg cttcttcaat catttcttct tcttgaagag cttgtcctag
    15001 atatagatat aacgattgat aatgcggatt aacttctcga agttcttcca gatagttgat
    15061 tgcctgctga ttttctttca attgaagatt cgtaaaagct agctggaaca gtcgatcatc
    15121 tgtcctttct tctttcagtg cttcttctaa aggtacgata gctgcttcga attctccttg
    15181 catacttaag gattgtccta aacgttcctg catcgagatt cctgaaattt catttatccc
    15241 gcttgccaac aatgtttcat aaaccactgc tgcctctttg aaacgatcaa ctgaaaaata
    15301 caattcagct agcgcaaact ggatcaatgg ttcatcagga agcaacccag ctgcttcttt
    15361 caattttgct tcactcactt cagggattcc gataacttgg tacaaatcag ctatcgccaa
    15421 taagctttgc ggatagtaat cactttgctt atccactttt tccaggtatt caaaagctaa
    15481 gtcgatctca ttatcttcga ttgcaatttc tgctaacggg atgttcagtc cgtcattttc
    15541 tgggtattgg ttgatcagtt gttcaaaaat ctgttttgct tcgatcaaaa agccaatagc
    15601 cagcaattct tcgcctagtt cagctaatat atctgctggg tcttctttta atgctttttc
    15661 taaaaagatt tgtgcttgtg acaagtcttc atctgataaa gcttgcaaca ttttttcgct
    15721 atttgtattc atttcaattc cctcttatct cactgacgat ttgttgaaat accgtcattg
    15781 ttctcaataa ttctttttcg tttggatgtt ggtatccgtc tattatacct attttttcta
    15841 aaacaagtat ttttttgctt ttttctgcca aaaaaagaac tttttccaaa tactccatct
    15901 ttgaaatctg ttccagccag tggattggat agccaagcaa gtccagccac acaaaaaagt
    15961 tttttagttg gaaatcaaaa ggatatgctt ggagattcca cacgaaatga aacatcattc
    16021 ctaaaaattt tttcatacta gcagaaagta gatggccatt ttcggtcaga taaaaagctt
    16081 gttcaaacag tttaccataa tttgacaggt tttctgcctc taattgataa aaatagatca
    16141 tttcttcgat catcccggca aacggccgag tcgttaattg ctttttattt ggatagtttt
    16201 tatacagatt ttgcaaaaaa cgatgatcac aaatcattcc gcaacagata aaagtcaaaa
    16261 agtcaatctg ctttccgtcc acctgccgct cgctgattgt ttgatcataa acgatgcgtt
    16321 ctggcagatt gatggtttgc agcactacac gatttggtag ctgcaaaatc gtccgctgcg
    16381 gtgttaatgc tcggcttaga gaacggatcg atacagggat catccatagt gatgaatcaa
    16441 gggttgtatg tttttgaaaa aaacctgcca gatccatgat cccttcattt ccaaatccga
    16501 tgataaacat ggattgattt tcgggatagc gtttgacgaa atcaagcagg ttctttaatt
    16561 ctgttaaatg attgcattga gtgttggcac aaatatacca gtcattgttt gcttgatttg
    16621 caaataacgg gttgatctta tctgcaaaca aatcataata gcgctgattc gttaaaaata
    16681 agattggctg atcaatggaa agttctctta gctgactgac tagcgtttct ccgtaaaaca
    16741 ctttcgtcaa cgcatcttct acttgataat caagttccat acgcatccct cctcttctta
    16801 tttttatttt accattagta agcaaattct agaaaagata agagcaaagc tcacctcata
    16861 acttgcaaat aaataaaaat taaataaaat acatgtgttt tctatgtatg acatacggat
    16921 tcggaatctc tgtctcttat ttattccttt tctgctagga aataaaaaga aaagcacttg
    16981 tagccctaga gccacaagcg ctttttcaac tgtcttattt aacagcgtct tttaatgctt
    17041 tacctggttt gaatgcaggt actttgctag ctggaatttc gatttcttca ccagtttgtg
    17101 ggttacgacc tttgcgagct gcgcgttcgc gaacttcaaa gttaccaaaa ccgattaatt
    17161 gaactttttc gccgttagct aaagcatctt gaatagttga aaatacagca tctactgctg
    17221 cagttgcatc ttttttagtt aaatcagtag ctgaagcaac tttttcgatt aattctgctt
    17281 tgtttgccat ggatagattc acctcctcca caagagatat gatagaaata tcatttagtt
    17341 aaaactttct gagtggtcca gaagtttaaa aagaaatatt gattaacttc aatattctgt
    17401 tatcacgata tcatatgaac cgcttaatag caaggttttt accaattttc acatgctttt
    17461 tttagtcata gaaacgtaac aaacgaaact gtctttttct tttgaaaaaa aaacgtcgat
    17521 atggtaaaat gcctattttc tcctacgagg gataattcgg atggacgtcc cttcaaaagt
    17581 aaatgctttt ctgatttgat tttctaagaa acgttcataa gaaaaatgca tcaattcctc
    17641 ttcattgaca aaaacgacaa atgtaggtgg tttgacagcg acttgtgtag cataaaaaat
    17701 cttcaggcgt tttcctttat ctgttggtgt tggattgatt gctacagcat ccataatgat
    17761 atcattcaac acagccgaag agatacgaag attctggttc atacttactt gttcgatcat
    17821 ttcaggcaga cgttccaacc gttgtttagt cactgcagaa acaaaaacga ttggagcgta
    17881 atcaagatac cggaattcat cacgaatctc ttgttcgaaa tcacgcattg tattggtttc
    17941 tttctttaca agatcccatt tattcacgac gataataatt ccacgaccag cttcatgggc
    18001 gtaacccgct actcgcttgt cttgttcccg aatcccttct tcagcattca gtaccatcaa
    18061 aacgatatca gaacggtcaa tggcacgcat tgcacgcatc acgctgtatt tttcagtatt
    18121 ttcgtatact tttccgcgtt tacgcatacc agctgtatct atcattaaga atttctgacc
    18181 actttcagaa acgaagtggg tgtcgattgc gtctcgggtc gttccttcaa tatccgaaac
    18241 aattacacgt tcttctccta aaatcgcatt gatcaaagag gatttaccaa catttgggcg
    18301 accaatcaaa ctaaacttaa tcgtgtcgtc gtcctcttct tcagtctctt cagagaaata
    18361 cttcactgct tcatctaaaa tatcaccaat ccctagtcca tggcttcctg aaacaggata
    18421 aggatcgcct agccctaagg aataaaattc atagatatcg tttctcattt ctggattatc
    18481 tactttattg actgctaaaa tcactggttt attacttctg tataaaattt tcgcaaccat
    18541 ctcatctgcg tctgtcacgc cttcgcgtcc gctgactaca caaatgatta catctgcttc
    18601 ttcaatcgcg atttctgctt gatgcttgat ctgatccata aaaggttcat cgccaagatc
    18661 aattccgcct gtgtcgatca cgctgaattc tcgacctaac cattcacctt ttgcataaat
    18721 acgatcacga gttactccag gagtatcttc gacaatcgag atacgctcac cagcgatgcg
    18781 gttaaaaatc gtagacttac cgacgttcgg gcggccaacg attgcaattg ttggatttgc
    18841 catattattt cctcctcaca agtttccaat ctcacttagt ttaacgaatg cattgccaac
    18901 tttcaagcat agattgtcaa ttaaacgaag tatttttatt ccttattgaa atactaatcg
    18961 cttttcaaaa gaaaaactga gacaaaagca gctgctttca tctcagtcac agatacaaaa
    19021 tcaattattt ttcagaatca tcggttgctt tttcttctac ttcttctttc aacgcatcac
    19081 ctaaaatgtc tcccatagta aatccagtat tttcttctgg taattcataa gactcaacat
    19141 tttttggttc ttcttctgaa gctggttttt cttctaaagc tttgatactc aatgcaatac
    19201 gatgttcttc tggatggatc tctaatactt tcactttcac ttcgtcacct tcatgaagca
    19261 cttcatgtgg tgtcgcaata tgtttatgtg aaatttgaga gatatggact agcccttcta
    19321 ctccagggaa cacttcaaca aaggcaccga agcttgtcaa acgtttaact gttccgtcta
    19381 atactgtgcc aactggagct tttgtatcga tttctgacca aggtccaggc tgtgtgtctt
    19441 tgattgacaa ggaaacacgt tcttgttcag gattgataga caacactttg acatttacat
    19501 catcattgac agccaataca tcacttggtt ttgctacatg actatgtgaa atctctgaga
    19561 catggactag accgtcaatt ccgcctaggt cgacaaatgc gccaaaatca gtaagacgtg
    19621 caacacgtcc actgagaaca tctccctcat ggatagttga aagaatttct tttttctttt
    19681 cttctctttc gttttccact accgctttat gcgataagat caaacgattt tctgatggtt
    19741 cgatttcgat gattttaaag ctcaatgttt tgcctttata gtctgaaaag tctgcaacaa
    19801 aatgatcttc caccattgat gcagggacaa aaccacgtac accgacgtca acgactaaac
    19861 cgcctttgac aacatttgta acaggtgctt cgatgacctt gccctcttgg aaatctcttt
    19921 cgatatcttc ccaaactttt ttagcatcta aacggcgttt tgaaagtaga tagctgccgt
    19981 tttctttatc tttgccgatc gtactgataa cgactaaatc taatacatca ccgactttta
    20041 ctacttcgct gatatcttct accggcaaag ttgataattc ttttgccgga acgactcctt
    20101 caactccagc cccttcgatt ccgacaatca cttgtttgtc ttcaatgact aaaacttcgc
    20161 ccttaacaac atcgccaact tttacttctt gtacgctttt cattgcgtct tccattgact
    20221 ggttgttctc ttgattttga tcaaattctg tcataacact tgtcctccta accaacattc
    20281 tgccgtaagt acggtactgt ttttagttta attgattatt caaaaaaaat aaagcgattt
    20341 cgttcgtttt ccttgaaaaa acaattgttt ttcatttttt ttcttaattt aaaaaagaag
    20401 ataacctttt ttcaaaacaa cagcttttat tgctgcaacg acttctggaa tcgatttgcc
    20461 agtcgtatcg atacgaacag catcctctgc ttgcttcagc ggagagacgt cccttgttga
    20521 atcataatgg tctctttcct gtatctcttt cgtcagtgtt tcaagatcag tcggaattcc
    20581 tttttcttgg ttctctttga aacgtctttc tgcacgctca cttacgcttg ctactaaaaa
    20641 gattttcact tctgcattcg gtaatacagc tgtcccgatg tctcttccgt ccatgacaac
    20701 gccaccgcgt tcccctattt ttcgttggac agcaactaat tcttctctga cttttccatg
    20761 tgcagagact tcagaaacag cttttgtgac atctggttga cggatttcta aagtcacatc
    20821 ttttgatgct atgaatacat gctgtccatc ttcttgttgc gaaaaagaga taggatactt
    20881 tttgatcagc gaaactagcc cttcttcatc tgaaaaagat acattgttcg taatagctaa
    20941 ataagttact gcgcgataca tggcaccggt atctgtataa atataattca attcttttgc
    21001 taatatcttg gcaacggtac ttttcccaga tgaagcaggc ccgtcgattg caatactgat
    21061 ttgtgtcatg atataactcc tttttctcag aaaaaaagcc gcaaagcgcg gctattatta
    21121 tttaattctt aattcttgac cagggtaaag cataaagttg tttggatcta agccattcaa
    21181 ttcaaacaat tgatcagtgg tgatccctgc acgctcagcc acttgttttg gaccttcgcc
    21241 tgcttgaaca gtcgttgttg aaccggctgc agctgatgaa gaaggtgttg tttctgctgc
    21301 attgctgctt gaatcccctg cttgataagt tgcctcactt gaggaagtcg gtgttgtctc
    21361 tgctgcaata ctgctttctg acgttacacc tgtatcttga gacacagtag attcttccgc
    21421 gattgtacta gattctactg ttgaagtctc agttgactcc tcttttgttg tacttgtaga
    21481 actttctact actgatgtcg aagtttcaga agaagttgct gctgttgcat tgttgcttga
    21541 tccatttctg atccagaaat aagcacctgc tggaatagcg atacataaga ccagtaaaat
    21601 caaaaatagc gaaagaaata atgtatttcc tttcttttgt tgtctctgag aacttcttga
    21661 tgaaacttca tcatctgtat cgtagattgg ttgttcccat ggttcttgtg tttcgttatt
    21721 ttctgtagat tgatgtctat cttttctgct cactgtttta cctcctaaac tctatcgtgt
    21781 gtattatacc ataggaaaaa gtgtcttgtc ctaaaaaatc aatgttccat gtttttttta
    21841 aataaattta gtaaaatcgt tccccaatga agttgttcag tcttagaaaa aagcttcctc
    21901 tttggcagaa gttctgcttt tgctccatca atatcacaac aattctgcgg cttttcggag
    21961 agtttttcgc caaaataagc taagatgaat tttctgcggc agttttcttc attaatatag
    22021 cgaagcatct gctgcaggcg gaattctttt tctttttcct gacgtttgag ccgttccacc
    22081 caattttctg gtttttcaga ctgctggatc agctccatcc attttttttg cagctcatca
    22141 aagggagctt gctctgtggc atattccaaa taaagctcaa aactttgtcg ctgttctcta
    22201 gaaagttgat taaagaaata atggatacgt tcatccccac tttgataaaa aagaattgct
    22261 gcactttctt cctgatctct gcctgctcga ccgatttctt gtacatagtt ttctagactg
    22321 tctggcaaat cataatggac cacataacgg atatcagatt tatcgatccc cataccaaat
    22381 gcattcgtag caatgagaaa ctgcagctga ttttttacaa actgctgttg aagttgtctt
    22441 ctttgagctg catcaagacc accgtgatag tatccaactg taaaacgttc cctgaataaa
    22501 tgatacaatc gttcgacttc tttttttgtt gcacaataaa tgattgccgc tccttgtgct
    22561 ctttccatga agtgttcaag ttcttgttct ttttgctgcg ttttccgaac aaaaagcgag
    22621 atattttgcc gattgactga ttgtctgatc tcttttggtg gtcgatcaaa tagtacatga
    22681 cgtatatctc ttgctactaa atctgttgct gtcgccgtta gtgccagtgt gaccgggttt
    22741 cctaaaagct ttcggatttt tcctaactgt tgatattctg gacggaaatc aactccccat
    22801 tgagacacgc aatgagcctc atctactaca tataacgcaa tattttgttt tttcagatgc
    22861 tctaaaagag aaggattagt caacatttcg ggactcaaaa acaaaaattt atattgcgat
    22921 agatgacgga ggacgtatct tctttcagat tgcgaaagta aactattgaa agcagctact
    22981 cgtttctccc ctcgtttttg taattgcgtc acttgatctt ccattagaga aagcagcggt
    23041 gacacgatga tgaccagacc ttccattaaa taccccgtca attgatagca aaggcttttt
    23101 cccgttcctg taggcaaaat agcgagagta tcttctccat caagcaacgc ctgaataatt
    23161 tcttcttggc cgggacgaaa tgaatcaaat ccaaaatatt tttttaattc atttattaac
    23221 attctgtatc gcttcctttc tcaatagata gatttgatac aaacgaaatt ctccataatc
    23281 taattgtcca tctacattcc attcgctaaa gcgccactct cgcacggaat ccttatttgg
    23341 ttccaaacgt tcgattgttt ctgcagagag aatccactcg tatggaaaat catcaaaaaa
    23401 caaggcccac tcaataagat gatctgttac tgttcctctt tttaaatgac ggattgccat
    23461 gatctggtca attgtctgac cattcataaa catctgcttg gtgatcatca tgctttgatt
    23521 gaaattttgc tgtaataatg aatcgatcaa agcgtgccaa agcgaatctg gccgtttttc
    23581 gatttgtgct aacaaaaggt ggatacatct gctttgttgc agataaaccg ctgactcatc
    23641 attgtttttt gccagctgat aaggaagcag ccctgttcgc tcatttccag ataattggtt
    23701 agctaaaaaa tctgctgctt cttctggtat ctccgaaaac agctgcacca aactctcata
    23761 cgcagtatca atcaaaattt cacgtggcaa ttggctttca ctaagccatt tttttagttg
    23821 gaaagtataa aaaggacttg tctctgctgg aagatagtct tgaatacccg ttgccagatt
    23881 agaaattact tgaacagcaa atttaatgag ccgccaacta gtttcccctg ttctgccata
    23941 gcggtcaaaa cgcaaaccag tatgttctat ttgatgttcg gacaacatat cagcccctgc
    24001 aggcgttagc tttgcttcat tttcatttat ttcgatccaa ccttgctgcg caattttttg
    24061 caaaatttga taaaacttat cctgcttcaa ttctggaaaa ctgttatgga taaacaaaag
    24121 ttcgtgggta aatccataaa taagtactga agtcgttcgt tttcccacaa ggagttggta
    24181 aagagaacta atccgcagct tgtgtcctga tgaaaatagc gataaaataa aaacaatcat
    24241 attattctcc ttaagttagg atggttagaa atgtcactac tatgtaaact tgtacctgaa
    24301 cgctgtattg catgcggtct ttgtcaaatc gaagcgccag atattttcga ttatgatgaa
    24361 gaaggaatcg ttttatttgc ccaagaacca gaggctcatc aacagttcgt gatgccggaa
    24421 gaagaaacat atgtaaaaaa agcgtatcaa aaatgtccag ttcgagcgat tttattagaa
    24481 aataaaatat aaatataaac gaaactttaa aaacgtacac taagttctct aaacttgaaa
    24541 ataagccggg atctgtttct cttgttccgt gaaatcccga cttattttga aagattcatt
    24601 tgctatctat agttaattga ctagtttttt cacggaccct ataggaccca tttatattat
    24661 ttcaactttt tcagccagtt ttccaatgta ttgacgatca cagtttgctg gtctgcgtta
    24721 gaaatttctg cctctccatc tcctttttgc tcaccatagc tgccaaaacc tccatgattt
    24781 ccgccattga ttgatacata ctctgttctt tccggtaaat actgcttagc ttcttgataa
    24841 gcttcctgat tcaatacttt atcttttgtc gccgtgatcg ataaaacagg aacagctgat
    24901 tctgtcaatg ttcctttttt gtcgggataa cttgccatga agaatacccc ttttaaatgt
    24961 ttgtctgaat gattcttatt gacataacga cttgccatta cgccacctaa tgaatggcca
    25021 ccgatcacat aatcggaatt tggaaaatct tctttgacct tatccgcttt gtttccgccc
    25081 atcactgcta gatcaagtgg cattttgaca atagcgactg aaaagccgtt ttttgctaaa
    25141 tcttgcgccc aaatactata actttctggc tctacgagag caccaggata aaaaataagt
    25201 aatggagact ttccatgatt ctttttctct ccttcaaaaa ataagtaatc ttctttgttt
    25261 tttccttctt ttaccaacac ttgcgcttct gacgatggtt cgtacgtatt ttgctgtata
    25321 tagtaataac cggctccacc gagtaatcct aaaatgatga ctaagccaat tagtattcgt
    25381 ctaaatattt tcactttctc ccaccttttc tatctgagtg accccttttt cttaatcaag
    25441 tatgattata ccttaaaaaa ataagagaga aatgcaaact ttccagcatc aaataaaaaa
    25501 agacggaata tccatttgaa tatccgccct ttttgtatgt ttatttttat ttagcacata
    25561 aacgatacac agcttctgca taaatttcca ttgctttata catactactt aattcccatc
    25621 gttcattcgc ctggtgcata aagtcaggag tatcagggaa catcgcaccg aatgccacac
    25681 actggttcat cgtacgagca aaagtagcgc cgcctgatac aaacggttca gtcatgtctc
    25741 cagtaatatc gcgatatgtc cccaatagat ttttcactaa ctcactgtct agtggcacgt
    25801 ataatgaatc aaggaagtca aattcttcat aagtcaaccc atatttttct gctgttttag
    25861 ttaatttagc tactaaatca tctttcttga atgtaacagg gattctcata tctacaccga
    25921 tttttgtttg ttctggtgtg atttccaaac ttgcaaagtt catcgttagc tcgccggatt
    25981 gttcatcttc tgttttgccc acgacagctt caccagttgc attttcttga actaattttc
    26041 ctaagaaatt gattgggcca aaatcaaata cttctgaaag agcaattgcc agacgagaaa
    26101 tagcattcac tccttgtgct gcatctttcg cgtggatact tttaccaaga acgacgatgc
    26161 cttcaccttg ttcttcgaaa tcgaattcgt gttttttcaa tgcttctttt acttcagaaa
    26221 gcttttctcc agagtaagga gctgcatcag gaacaacatt caacgctcct ccagctttta
    26281 cagaaaactc gttcgttcct ggtcctgtca agtaagcttg caataagcct ttttctgcat
    26341 aaattaaagg aaattcagca tctggcgcaa atccttgcgt aattccttct tctttttcgt
    26401 tatatttttc taaacaacgc cataaatttt cttcatctgt accaaagata aaacgaatac
    26461 gtgtcttgaa ttccacgcca gcatcaatca aagctttgac ggcatacatt gccgcaatag
    26521 aaggaccttt gtcatcttgg gatccgcgac caactaacca gccgtctttt atagttggat
    26581 cgaatggttt tgtttcccaa ttattttcgt cccctgctgg aacaacgtcc atatgacaca
    26641 agataccgaa taattcatct ccagagccaa tctctgaata accgtaatag ccttctggat
    26701 ctttaaatgt tctaaatcct agcttttcac tgatttccaa tactttatcc aaagcttcaa
    26761 tcactttttt accgaaggga tgtccttgtc ctgaatctgc ttcatctagt acggaaggaa
    26821 ttcggatcaa ttcgctcaat gattctaatg cttgttcatg atgttgttct gtcacaaatt
    26881 ttttcatgat attatcctcc taatatgtta aaaagggtca tgtcaaattc ctccgacaca
    26941 acctcttctt ctcaaataat gacgttttaa gcctgctcca tcagcaagca gaatgttctt
    27001 aacaaatgat gaaagaaaaa acactcactg aatggagcta ttgacttatc cacgtgctta
    27061 tcgatagccg tttatcggtt tcttcattct tatgatagac cttgtacctg tatttgtcta
    27121 ggtttagaac attgctgcta cacctaggat cacacagatg gctacaaata atatcgcaat
    27181 taatttaccg gtaaatttcc accacactga aacatcgaaa cgagcaattg ctacagcacc
    27241 cattacgata gcagatgttg gtgtaattaa gtttactaaa ccagatgcag attgataagc
    27301 agtgattact aaatccttac cgacgccggc aaattcaccc ataggtccca tgattcccat
    27361 tgttgcagca gctaagccgg aagttgaagg aatcaagaat gacataggga tatagaaaat
    27421 aaatgtaata atgatgaata cacttgaaga taatgaactt aatccttgtt cgccccaatg
    27481 taagatggtg tctgtgatta atccattgtt cataaccact tggataccac gagcaacagc
    27541 tactacgatt gctacaccga tcaaatcaga agcaccagct aaaaattcag agacaaattc
    27601 agactctttc atgccataag tgattgctac tacgatggac attactaaga ataacatagt
    27661 aatttctggg aagtaccagt cacctaatgg aagcatgctt ttacctagaa ccgtacctag
    27721 taccggaagg tttgttaacc agtttgtcaa tgattcaaaa atcgtgaaat tcgcattcaa
    27781 ggttgtccaa ggaatcaaac tgatgatcat gataccaaaa gtaataaaga acaatacatt
    27841 aacatgtttt tgttttttcg tgattacttc ttgacgaccg attgcttcaa tatcgaaatg
    27901 cttcatatct tctttacgtt ggttgtatac taatgatttt gttggatctt tttcgatctt
    27961 tgatgcataa cgatacacat atacaataga aatagctaac aaaataacga acatcaagaa
    28021 tcgaagacca ataccttcac ccatcgaaat cccaacagct tgtgaagcta cgcctgttgc
    28081 aaaaggattt accgttgaag ctagacagcc tacttgagac cctactaata cgattgctac
    28141 agctactact gtatcaaagc ctacagccat catgactggg atcagtaaag catagaatgg
    28201 aatcgtttct tctgccattc cgtaagtaga gccgcctaat gcaaataaca gcatcaatac
    28261 tggaataagc attttttctt ttcctttgaa tttcttcaca actgaagcaa tcccggcatc
    28321 tagtgcccct gttttgttga taatacctaa aaatccacca acaaccaaaa tgaagaaaga
    28381 gattgggatt gcagcaggtg tttctttagt tagctccccc gctggtacac ctagcatccc
    28441 attgattggc gccatgaaaa tatcccacag cccttgagga ttttgttgta ctcgttcata
    28501 tgatccagcg acgatgttgc ctgcatcgtc tacactatag tgcccagctg gtataaacca
    28561 agtaagtaca gcgattactg caataataat aaataagacc gtatacgctg aaggcatttg
    28621 aaattttttc ttttttgttt gttccatctt cttcttcctt tcttttccgt tagagacaac
    28681 aattttggct ctaatgttat tttatcaaaa agagtatcag aacaaaaata ataacacgca
    28741 ttttgtaaaa cttttgttca aaaagttcgt ttttccctat tccctcctct tttttcaggt
    28801 ttttaaagct ttcttctttt tcattgtagc gtttcctttt ttttataaac aaacattttc
    28861 gtcttttaaa aggagaagaa tttcacattt gcaaagaatt gattgatttt tatgcataaa
    28921 tcaaaaaaat actcaaaaca aacaaataaa acgtttacat tattgcatgt cttgtatttt
    28981 tttccaaaaa aaaagaccaa gaaatttctt gatctttttg atatttattt gactgctgta
    29041 tgacgttgtt cgaactgatg ttgttttcga cttaaccatg gaagaagttg cgcatgcagc
    29101 actaaaaaga cagcactcac gatgaatcct ttgatcaagt tgaaaggaac gatcccaatc
    29161 agtacatagt ttgctaaaga catgcccagc atctgtgttg cgttcagccc taaaaacatt
    29221 aagtaaagag gcgtaataac gaaataattt gcgatactca taaaaatagt tagagcgatg
    29281 gttcctgtaa tgacacctaa aaatttgttt cttcctttat gctgtttctt tacactaaag
    29341 aaataataaa tcgggaatgt aaagatcgtt gttgataaga aactagcagt gtctcctacc
    29401 aaattatccg gagaaaaacc tgtagtcagc agatgtaata ctgaacgcaa gaacgctgtt
    29461 gcaactccgg ccgctggacc gaataagaac atgctgatca ataccgagat atcactaaaa
    29521 tcgatcttca aaaaactaaa agccggcatg atcggaaaag caaaatactg taaaactaat
    29581 gcgatcgcag caaacatcgc tactgcaacc attttctgta cacgggtgtt cttcatttga
    29641 aatcctcctg ttaggactcc tcttcagcga actttttgac gtttctctcc aaatgaaaaa
    29701 actctatttt ccagggaaaa tagagttaga gttatttgat caagcgtcgt caaataagct
    29761 ctatcttctt tatccagact atactgtcgg tatcggaatt tcaccgattc agctattttt
    29821 ttgcaaaata ggtcgtggac tataaccacc ggtcgggaat ttcaccctgc ccctgaagac
    29881 gaaccttata taatttttgt ttacatattc attatacata tctattcaaa aaacgcaaca
    29941 tctaacactt ataaaaagta agtgttcatt ttgagtggtt cagcaaactg ctgacttctt
    30001 ttttgttcag ttcacggtaa tccccaggac gtaggccttg taaagtcaga tctccgtatt
    30061 tttcacgttt tagtttttgc acaggaagac caactgcttg aagcatattt ttcacttgat
    30121 gattacgtcc ttcgtggatc gtcaattcca cgatactgtg gtttgtctta ggatccactg
    30181 ataaaatttg gaatttagct ggagatgttt ttcgtccttc gatctttatt ccttttgtca
    30241 aaggtgcaag catcgatttt gtagcgatcc cttttacctt tgcaacgtaa actttatcca
    30301 cttcatgttt tggatgtgtc aggcgctgag caaaatctcc atcatttgtc agtagcaaga
    30361 tccccgaagt atcgtaatcc agtcgaccta caggatagat acgttctttt accatcggca
    30421 aaagatccgt aacaactttt cttcctttgt catctgcaac agcagaaata actcctttag
    30481 gtttgtacaa taaatagtaa ccgtattctt cttgataaat tgggacttca tccacttcca
    30541 cagtgtcatg tttcccaact tttatcccta attcccttac aacttgtccg tttactttta
    30601 cacgtcctgc aaggatgaat tcttctgctt ttcgacgaga agtgatgcca gcgtgggcaa
    30661 ttactttctg caatctctcc attacaatta ttctccttta ttcattccat caaagaatag
    30721 atctggtgac acgtcttctt caagtgaaat ttccatttct tgtgtatcag gcagttcttc
    30781 taatgatttc aaaccaaaat aatctaagaa gtagccagtt gttccatata atatcggccg
    30841 acctggtcct tctactctac ctttttcttc aatcagttta tgggcagcta gacgctgtac
    30901 cgctcctgaa acctgaactc ctcgaatctg ctcgatttca gctcttgtga ttggctgttt
    30961 ataagcgatg attgctaagg tttcgacggc ggcttgagat aatgtgtttg atgtcccttg
    31021 cgcatatcgc ttaagtaagg gagccagctc ttttttagtc gttaatacat aatggctttc
    31081 cgtttcaaaa atatgcaaag ctgagtgcga gttttgagtg taagattctt ttaattcttt
    31141 cactaaactt gtgacttctg cttcgctgag atttaacagt ccgcttaatt cttcattact
    31201 gatcccttcc tcgccaacaa taaaaagaag ggcttcaagt tcacttaatt tcgtcatgtt
    31261 cggtatctcc tactgctgga taaagcataa ttgattcata gttttctttt tgttgcgcaa
    31321 tgatctgccc ttttttcatc aattctagca aagccataaa agtagtgaca acttcacttt
    31381 tagaaggtga ctcaaaaaaa gaatcgaaag tacagccatg cgcatttctt tttatacgct
    31441 cttcgataaa taccattcgt tcttcgatcg ttgtgtcatc gggcgtgatc gttttttcca
    31501 ctttttgaga aaatttctta cgttctaaga ttttctgcat ggcacggatc aaatcgattt
    31561 ttttgacttg tcctcgcttc aacggctttt cagcatccgc taacccatcg atgttcatag
    31621 gttcttttgt gtaataaaga cttcgttcct ctgctttttc tgtcagtctt tcagctgcat
    31681 atttatattt acggtattct aaaagctgag tgaccaattc ttctcgagga tcttcttccc
    31741 ataattcttc atcgtctgtg acgaattctt ggacaggaag caatgtcttg cttttgattg
    31801 ccatcaatgt agcagccatc actaagtatt ctcctgcaac agctagctcg agtgttttca
    31861 ttgtatggat ataattcata tattgctccg tgatcgtagc gatcggtata tcatatatat
    31921 cgatttccat ttgctgaatc agatgaagca gcagatcgag aggaccctcg aatacatcta
    31981 atttaatatt gatctccgtc aactcattca ctctttcttc tttttctttg ctagccattt
    32041 tccaatgtaa ggctctgtga tttcagttgc acggatggag acatccgggt acttttcctg
    32101 taattcatct aacatttgaa agcccatatt ctcaccgcga taagacggat tcaaagaaat
    32161 gtcatggatg atcagctgat cgttcgttgc ccagtaaata ccaataatcc cttgaatgtt
    32221 ggttgaacct tctggcgtaa agaaaaaaag ttcataatcg tcttcagatt cgtacgtatc
    32281 aatctccttc aacaaagaag ttttacctgt cagtttctta tggaaactca atagtcccat
    32341 agcaatttta cggttttctt tccggtaatg tgttaacatc ttctcacctt cctatgacta
    32401 agcccttgga aaatgctgct tataaacatc cgtcattctt ttcttcgtga tatgtgtata
    32461 aatctgagtc gtagagatat ccgcgtgacc taacaattcc tgtactgtcc gcaaatcagc
    32521 tccattttct agcagatgtg tggcaaagct atgccgcagc gtatgtggtg ttacttcttt
    32581 gtaaatccca gcctctcgta ctaactgctt cagatttttc cagattcctt gccgagaaag
    32641 acctttccca tgattattga caaatacatg catttcagat gcgtccttta caagtaatgg
    32701 acgtgcttcg tctaagtagc gttccagcca ttggatcgca taatcaccta aaggaatgat
    32761 ccgctcttta tctccttttc caactgtctg taccagtcca agagaaagat gaagatctcc
    32821 caatttcaat ccaatcaatt cactgacgcg catcccagta gcatacatga cttccaagat
    32881 tgcacgatct cttatcccta acgtttttgt cgtatcaggt gcttcaatca gcttttctac
    32941 ttctgtcaga gtcaatgtac ttggtaattt ctgtgctttc ttcggcgtat cgatatgttg
    33001 catcggatca tgatcagtga tacgctcttg ccgtaaaaac tgatggaatc ttctgagact
    33061 tgagatcatc cgagtaacag ttgctgtcgc ttttttttct tcatgcaact tctccagaaa
    33121 acggatgact aaaaagcgat cgacatcctg ccatgaagca attttctgct cctgtagaaa
    33181 atgcaagtac tgttccaaat cacgttcata gctttgtcgt gtattggcgg acaatccccg
    33241 ttcaatattc aagtagtgga gataatcgtt gatttgctct ttcataataa tccccctcat
    33301 gcctctctat catatcagat accgcttcat tctgatagtc tttttccata atctgagcaa
    33361 agaaaaagcc gtctagacac tcagacggac tggtttcttt tttctttttc atagcattcc
    33421 tgacagattc catggaacgt tagccgatga tcttttacta aaaaatgata acgttcttct
    33481 actacttgct ccacttcaag taaaagatcc tcttctactt cctcgatcgt gccgcagttc
    33541 aagcatagta aatgatgatg gaaatgtttg gcgccttctt ttctcaaatc ataacgggct
    33601 aatccatcat taaaacttac tttatcgaca attttcaatt ctgtcaagat ttcaagggtt
    33661 cgataaacag tagcaagtcc aatttccgga ctcttttttt tcactaaaaa gaagatttct
    33721 tctgcagata aatgctcttt ctcattttcc aaaagcacaa gcagagtagc ttctctttgc
    33781 ggtgtcagct taaaccccgc ttcatgtagc tgctgttttg tttttttcat cgccgaaata
    33841 gcattcatga ccatttactc aaccccaaca atttataata attacaaata aaaaaagata
    33901 taacactatg ttaattaaaa ttattataag ctagttaaga aaaacatgca agggattctc
    33961 aattagattt tttgactagt tttgtcacac cgttttcttg tgtaatcaat ccttgtttca
    34021 aaagattacc taatgcgcgc ttaaatgctc ctttgctgat accaaaagct ttcatgattt
    34081 cttctggatc cgatttatct gtaaagttga tttgctgatc tgcagaacgt tctaaaatgg
    34141 ttaaaatcat ttgtgcatca tctgatatag cttcatatgc tcttggcttc aatgaaagat
    34201 tcagtacacc gtctggtcgg acaccaatca ctcgaccttt tatctgctcg cctagacgag
    34261 gttcattata tcgttcagaa ggatggataa acccaagata gaaatcttcc gttaaaacgt
    34321 acgtacctgt taatttcaag cggtatgctg ttcctatcac atctttgttt ttcatttctt
    34381 ctgttccata tttgcttaaa gatttgaata ttttttcatc tgctaaactg ccccaaatac
    34441 ggtcttttgc atcaactcta agggaaatca tcaagcgatc ccctttttta ggccatagct
    34501 ctgtcattgt cggcaattca tcaagagata cgacaaagtc tttatctgga agaccgatat
    34561 cgacaaacgc acctaaatct tttcgtgtag cagtaacgat tccaaaagcg taatgaccga
    34621 tacggctttt aggaatttgt gtagtgatcc gattttcatg tttttgattt tggtaaccga
    34681 atccttcaac tgcttcaccg attttgtgtt caccttctga tttgcttaag ccaaaggttt
    34741 gtccgttttt ttggacaaag tagttttttt cattttcatc aataataata cctgtaaata
    34801 tagttgctaa taaatcgttc atttttttct ccctctatag tgaaaggttt tcttaataca
    34861 tttctttgct atcataacat aatgttatct acttgaatag ctgagccttg gtttggaaag
    34921 gtgaaaaaag gagtatgaca acagttgtgt catactcccc tttttcgaat aaacggtgtt
    34981 aaacggcagg ctcacagcct ctttcatttg cctaaaatta attgctccca tttcctccga
    35041 accatccagt tttacagttg atggttacga tgtaaaatgg caaagcactt tctccaatgc
    35101 ctttcatcaa tgcagatttt gttgaagtgg catatagatt ataatagcct tccccatttt
    35161 cgattctggc tttttctaat ctgtaacctc cttcaacgat atatccacgt tggatacatg
    35221 tagcaatcac tttgctttgg acacctggtg cccacgtcca tgctggatta gatgcatcgg
    35281 caatatcact tgctctggca gatttgattg gctgattcgc tgagtttgaa gaggaagggg
    35341 tcgaggatgc cgcttcttgc tgtgctgctt gtgcgaccgc agcttgttga gcggcttgag
    35401 ctgcagctgc tgcttgagcg gcttgttttg cttgttcttc agctgctttt ttcgcttctt
    35461 ctgctttttt cttttcctct tcttcttttt tctctttatc agtgagcatc ttatctactt
    35521 gtttcaattg ttcattcaac tgagcagata gatctgtatt tttcactttt tctactgctt
    35581 cttttgccgt cttgtattgg tcgcgtgttg ctgaatccac tacttttccg tctttaaaga
    35641 ctatagctgt tttttcttta gctgtttgca attcagcata ttgattttta gcttctgttt
    35701 gtgcttgttg aatcaatttt ccaaaatctg tgttatccgt ttcgattgct tggatctctt
    35761 tatctgcttt caacttgatg tcatctgcta gatgatcatc gacgatggca ggtgctatga
    35821 accactcatt cactttttgg atatctcgga tcttagattg gatatcttgg taagttgttt
    35881 ctaactctga atatcctttt tcattcttaa gactggataa atcatttttt agttttgata
    35941 aatcttgatg aatcatatct gcacgaataa attgatggtg atcatctgta taaaaggcag
    36001 caagtttctc atgaagttct tccatttgtt gctgtctttt tgcttctgct gctacttcgg
    36061 cttctacttt ttgatgatgg tcataataag cccagcttcc tccaccgagt agaagtactg
    36121 ctgctaaaac gagataaggt actttttttg attttttctt ttgcgcttta tctggatctg
    36181 ttttttctaa gtttgattct tgatgtgttt tttcagtatc tggcacgatt gttattgatt
    36241 tcgcttctgc ttcaaacagc ttaggctggt tctcttcttt ttctattttt gcttcaagat
    36301 cagtaccctc tttgcttaca gattgatttt cagcatcgga ttcactattt atttcatcgg
    36361 gctctgttga ctttttgtct gtgttttcga gtatttcttt tttctctgct tccggcagtt
    36421 tattcgtttt ttccttttct aattgttttt cagtaaatac ttcagttttt tctgtgatat
    36481 ccgtttttac gtcttttatt tttactgttt ctttacctgt ggcgttttct ctatcagagt
    36541 ctttttcagt ttcttgttcc ttttctggct ctactttgtt ttcctgtgca attttttcac
    36601 tgatcatttt gagcagctct ttcgcgtgct cttcttttgt atcttcacga tgtgctttga
    36661 tataagcgga tagtatcgaa ttttcttcct cattatcgac gatttctttc agttcagcta
    36721 ctcttctttt ttgttttgat tcaagcgttt cttcttgatt ctttcctgat tcttccgaag
    36781 tctcatgaac agttgctttc ttctgttcat ttttctctat attagttact tgatcgtgag
    36841 caggtggttc ttcgtcttct ggttctgctt tttcgaataa ttccattaca gattctagag
    36901 gtaaatcttt caattccgac cattcgattg gatcgtttaa ttctgtatca ggaaagactg
    36961 catcttcagt tgatttatcc tgcatagctg catctgtatt tgtttcttca attgattctt
    37021 ttatttgctg atcttctgca gttatttgat gaccgcagtc tggacagata gtattctgct
    37081 ccattttttt cgatccgcaa tttggacatt ttttcatcac ttagcgatcg gctcctttac
    37141 taggtttacg ctaccattta atctatcata ttctatacgt cacgccaata gcttattttt
    37201 aggatttact taaaaataat gaatgaattt ccttcctata gaaaaaaaag cttgagactg
    37261 cgtagtctca agcttttttt cttttaaaat aaaccaaaca gttttactga tttctcttct
    37321 ggtcaatagt ccacgcttat tctaagaaat cttttaattg ttttgaacga gaaggatggc
    37381 gcaattttct taatgcttta gcctcgatct gacgaatacg ttcccgagta acaccaaata
    37441 ctttccctac ttcttccaat gttctcgtcc ggccatcatc taaaccaaaa cgtaagcgaa
    37501 ggacattctc ttcccgatca gtcaatgtat ctagtacatc ttccaattgt tcttttagta
    37561 actcataagc tgcgtgttct gctggacttg ttgcttcctg gtcttctatg aaatcaccta
    37621 agtgagagtc atcttcttca ccgattggcg tttcaaggga aacaggttct tgcgcgattt
    37681 tcaagatttc tcggactttt tctgttggaa gatccatttc cgcaccgatt tcttctggcg
    37741 taggttctct tccaaggtct tgcagcaatt gacgttggat acgtatcaat ttattaattg
    37801 tttcaaccat atgaactgga atacggatcg tacgtgcttg gtcagcgatt gctcgagtga
    37861 tggcttgacg aatccaccat gtagcatagg ttgaaaactt aaatcctttg cggtagtcaa
    37921 atttttcaac tgccttcatc agtcccatgt ttccttcttg gatcaagtca aggaactgca
    37981 tgcctcgtcc tacataacgt ttagcgatac ttactactaa acgaaggttt gcttctgcca
    38041 gacgctgttt cgcttcttgg tcgccttctt cgattttcaa tgctaacgct acttcttctt
    38101 ccgcagttaa aagggagaca cggccaattt ctttcagata catacgaacc gggtcattga
    38161 tttttacacc ggttggcgca gaaagatctt ctgtttttgc ttgttcagct tttttctcag
    38221 cactcttcaa gctgtgaatt gatggatcac cattttcatc caccacactg atacctgcgt
    38281 cttcaatctt ttggatcaat ttgtccattt catctgcatt caaagtgaat ggtgtagcaa
    38341 gctgattgga taaatcatca tatacaactt gtcgtttggg tttgttttct ttgatgaaag
    38401 ctgctactgc tgcttcatac gtttttttat ctgttccatt tgccataaaa gaaggccccc
    38461 cttgagtagc tatttggctt gttttaactg tttcgttaaa ttgatgattt caatcgtcaa
    38521 ttcaagctca agctgtttgt ttccagttcg tctggcttct tgctgcattt gtttttttaa
    38581 tgttatttca tcagctaagc cagatttgct gatcacatct agcaagtctt ggatttctcg
    38641 tggcgaactt tcttctgcca ccggtaaata ttcgatttcc accaccaacc gccttaaatt
    38701 ttcatcttgc aaaaagtcta aaaactctgc aaggttgaat tcataatgtt gtgagacata
    38761 tgcatcgaat aaaaaataaa cttctgcata tgcatcatga ataaactgaa attctcgttc
    38821 ttttaaaata ttacggacag aaacttcttt aaatgcacga tataatagaa tctgctctgc
    38881 cttttctact tgcgtcaaag gtctcttttt ccgtgcagtt tcttgtctcg taacctgagt
    38941 gtgttgactt tcctgaggtt cttgacgatt ttgctgattt gtccttcgaa gatcgcgcag
    39001 ttgtttttgt atcgtctctc tgccgatctg aaactctgtt gacagttgag atagatacat
    39061 atcttgttcg attggtgaaa caactcggct aagttcaact agtaattctt cgaggtattc
    39121 gatcttgtct ttttcattat ctaaattttt cccttgtttt aaataacgtg atttaaaagt
    39181 aaagactgtt tcgcgcccat gagccactaa ttcttggaaa gatgcttctc catacttacg
    39241 gagatattca tcaggatcaa gcttttctgg aacgactacg acagaaagtg ctaatcgact
    39301 gttttgccga agcaattcaa tccctcgatt ggttgcttca aaacctgcgt tgtctccgtc
    39361 atagcaaaag accaattctt tcgtcagctt ttccatttgt tggatctgtt gagctgttag
    39421 acttgtcccc atagaagcta atccagtttt gataccagcc tgccatgcag caatcacatc
    39481 cataaaccct tcgaacaaca aaatttctcc gtttttccgg atatcgcttc ttgctttatc
    39541 aagattaaat aaaacttgtc ttttattgaa cagttctgtt tctggactat tcaagtattt
    39601 gggctgatct ttttcctgcc ctttttcagg tgcaagccag cgtcctgaaa aaccgatcgt
    39661 ctggccttga gaattacgaa gtggaaacat cactctttga taaaaacgat cagacatacg
    39721 gccatcatca tgcgtgacaa acaatccaga gcgttctaac aattcatttg aaattgattc
    39781 attcttgaat acttgctgaa gaaaagaacg ctcattaggt gcaaaaccta tgttgaattc
    39841 ttcaattaat tctaaagaca acccacgact ttgcaaatat tctaaagctg gctgtccagc
    39901 ttttgtatgc aatagcatgt gatgatagat ttccgctgct ttttcatgag cagcaatcag
    39961 tttccccgta gcagattcag gattttggac agctatagta cgctgacgcc attgatcttc
    40021 taacggtatc tgttcgaagt ctgccacttt taccactgct tctggaaaac ttagaccttc
    40081 tagttcttga agaaaagtaa acacgtttcc gcctttacca caaccaaagc aatgaaaaat
    40141 ctgcttgtct tctgcaacag aaaaagacgg tgtacgttct tcatgaaaag gacacagccc
    40201 caagtaattt ttaccagact ttttcaactg gacatattgt ccaatcacct caacgatatt
    40261 cgtttgactg cgtactgttt cgataacctc ttgaggaatc cgttgagcca ttttttcacc
    40321 ccctgctcta ttgatatctt ttgggtttaa cagaagatat ttcaggagaa taaccggtaa
    40381 aaaatcgcac taactgaaat cagtgcgatt ttaaaggaca caattataca tgtttgattg
    40441 tatcatattt cattgctttt tcaagtataa cacatttcta tctcattaag catcaatttg
    40501 ctactctttt cagtaactga ttttgaatat cagccttcca gtacaatact cgaagaacaa
    40561 tatttacgag catgaataca aagaagtatc ctacgctctc tcccaaccct aagtttactt
    40621 ccaaaattcc atggaacagc attgcagcta catatatccc tacgatcgtc gttactgcta
    40681 ggaagatgcg caatgggttg aagggataac aagcttttac aactgccatg caactgatcc
    40741 caatcagcaa gtaatacatc aaagtagtag tttcagcatt tccccatgcg aatgtttttc
    40801 caagtagata caccgcaatg atattcacta ctacaagcaa ggcatttggt aaagcattaa
    40861 taagtgctgt aggcaaataa cggtaagtga tttttctttt atcttgttca aaagataaaa
    40921 agaaggaagg atacccttca atcgctaaat caatcagcgt gatttggata gggataaacg
    40981 gaaatccaat tgctgtaacg gcacatataa tcgataaaat aaatgaataa atcgttttga
    41041 taaaaaagat gcctgagact ttcgtcacat tgttgaccac tcggcgtcct tcaaacagga
    41101 cttctggcaa tgtagtaaaa tcagagtcca acaataccag attcgcaatc tgacgtgttg
    41161 ctccatcacc ttctgccata gcaatgctgc aatctgcttc tcttaacgcc aaaacatcat
    41221 tcacaccgtc gcctgtcatt gcaaccgttc tgccgctttc tttcaattca tttaccagca
    41281 atttcttttg ctgcggactc actcgtccaa aaaccgtata gcgatgagca gcttctcgca
    41341 cttccatttc ttcagtaatt tgagaaagat cgacatacgc atcataattc ggtaatcctg
    41401 cacgtctagc gatattggag acagtaaaag gattgtctcc agaaatcact ttcagatcca
    41461 caccttcctc atgaagataa gctagtgttt cttgagcgtt ttttcggatt ggatcatcga
    41521 tttcaaacag agcaaccggc tcaacaaatg ctggtttttc ttcgttcaat tgctgatttg
    41581 gagcgatccc caacataagt acgcgatagc cattcgcttg ggctgttttt agactgtccg
    41641 gaagccgatc ttcttccacc aaacgttcag gcgctcctac gtacacgact cccagttctg
    41701 gaaattccat cgcgccccat ttgcgatcag aagaaaatgc gactttgttt gtcacatcat
    41761 accgattaga aagctcaaaa taatctctca tagcccgcat agtgatgttg ttatcactgc
    41821 tttctgccag atacgtcccc ataatttctg ggatggcttt ctcgtacagc ggatgtagtg
    41881 cttctacccg ctggatactc attttccctt cagtaatggt ccctgtttta tccaagcata
    41941 atgtatcgac atgggccagc gtttcaattg aatacatgtc ttgaacaagg attcgttttt
    42001 ttgccagttt ggttacccct gtcgttaatg caatacttat tagcaatacc aaaccctttg
    42061 gaagcatgcc taacaaagct gctgcagatg caataacaga aattttgata gaagcatcgc
    42121 ggatgaacag tgcttccaaa aatagtatga tccccaaagg aataatcacg aaactagtga
    42181 atttggatac tttgcgaatc gaatctacaa gttcagaacg aatagctttg tgagtctttg
    42241 cctcgctagt caagcggaca gcataattat ctgcacctac tcggataact tcagccatga
    42301 cagaaccgct tgtcaaaaag cttccagaaa gcaattcagc tccagtttct ttgacaatca
    42361 aatcagattc gcctgtcaaa agagcttcat ttgcttctgc ccgtccagat ataacctgta
    42421 aatcggctgg tatctgttct cctgctccga tttttaccaa atctcctaat accagctctt
    42481 tagtagaaat cgattgttct ttaccgtccc ggatcactag tacttctgat tgggaaacaa
    42541 tcgataattt ccgtacaaga tttcttgcat gtatttcttg ataaattcca ataacgatat
    42601 tgacgacaat aattgctaaa tacgccatgt tggaatacgc acctacaaat aacagacaaa
    42661 tcccaatacc aaagttcaga aaattgaata acgtcaatat attatcgctg aatatttgtt
    42721 ttgtactttt tgatgcatct tcctggtagt cattttgctg gccagaagcc attttctgaa
    42781 ctacctcttg ctgtgtaagt ccattcattt tctttttctc cattttccgc caactttcaa
    42841 aaataatcac gtgtttaagt ctagcgtgtt ccaagattaa aaacaacttg tttttataaa
    42901 atttatagaa aaacacacga atgattttac aaaaaagatg ccaacctttt tgtttgaatc
    42961 acccgtgtgc tgtttttatt atcaatctat ctttacttat attgttcctc caaacggctc
    43021 atccaccaac ctagtgctgt accggctata aaaagaacag gacaagctag taccccagca
    43081 actcccaatc ccgcgtaatc ggtaggaatg atcataatcg ttgaagcaaa aactacacct
    43141 aaaatgaaat ggaatagctt gctatatgcc tttgagaaaa tgtaatccat gatttttgac
    43201 aatccaagaa cacaaagaat cccaccaatt ccgatcggca caatcacttc aagtcgtact
    43261 tctttaaatc cgtcagccat cgctttatac aatcccatat acaccaaaaa attagaaggg
    43321 ctcaatcctg ggacgatcat acccaaacca atcaatccgc cggcaatcag ccatgttcca
    43381 aaattctgat cgacttgccc gtcaaataat tgagcgccgt ataataaaaa caaataagcc
    43441 agaacaaaag taacaaccat gatgatcaca tcagaagtat ctcttccttt tttccctgct
    43501 tctttccata acgcaggaac agttccagcg atacatccga caaaaaacca taatatcgtt
    43561 gtttcatacg cacctaataa aaaactgact aaaaaagaaa gtagaaagat gcctgtcact
    43621 ccgcctagac caacaggcag aaaaaacaaa acattttctt tgaaattttt tgtaaggtgg
    43681 gctaaaaaag aaatcagccg ctcatacatg ccaaagacag ctgctaatgc accaccgctg
    43741 actcctggca agataaatcc tgaaccgata aacattccct tcacaaaccg taacatccag
    43801 tctttggttg tgtaccccac ttcttgattt tccatttttt gccttttttc cactatttgc
    43861 gtactccttc tttcatttaa ttttattcat gattgaacat ttcctgctat tttacttaaa
    43921 gactttttca taggtctcta ttattttttc attcattttg acaatatcag gataaaacat
    43981 gttacctcca ttatgataga gatagccgcc attgtaaagc aaggactgga tccgccaata
    44041 tcggtattgt ttcccttcct catttcctaa aagtgggctc agcacatctt tagaatacgc
    44101 ttctgctaat tctactgtgt tttctccgcc atgatttttt acataggcaa tataatcttt
    44161 cccaaaatta tatgcttgga cagctgtcca taaatcgcat ccttgtttct ttgcttctac
    44221 tatcatttcc gccaaatatt tgacaccttg atcaatactg tcagctggat tatcaatgat
    44281 ctcagcttct ccatgcagac tttccgagct ctgcatgaga tctgtccctt ttccttttga
    44341 ttcggtcaat attatcgcct tgatcaaatt ctcgtagttt tccatatgat aattttttgc
    44401 agctgttgtt atttctattt gatagctttc cactcgtttt accgaacgat aagttcttcc
    44461 tcataaaaac aacaccgcac caataaccgt cagaatgatc atgtaaaaaa gaatacggat
    44521 aatagataat cgttttcgct tcatttcatc acctagttat tttgacatct ttttttatct
    44581 tactatttct ttatcttctt ggctatttct tccttgattt ctgtgtacgc cttaagaaaa
    44641 aatgaatttt cctgtatttt ttgacatctt acgaaaatga tcgttgtttt tcagtaaaaa
    44701 caattgccca atgactgata taatcgttat actttacaca gtaggtgatt atgtgaaaaa
    44761 agaaaagaaa tatgcaaaaa tgccagatgg gagcgaaatt tactatgaaa agagcggtca
    44821 aggcttccct ctctttttac tgcatggcaa tgacggcagc ggccgctttt tttcagaaca
    44881 ggtccctgta ctcgaacgct actataccgt gtatctagta gatagccgag gacatggtcg
    44941 ttcgacaaac gaagcatcta tgttgaattt tcagttaatg gccgaggatc tgaatacgat
    45001 catgttgctg gaaaaaatcg atcaggcaga ttttcttgga tttagtgatg gagcaaatct
    45061 agcactggta tttgccagca gcttccctaa aaaagttcat cgattgattt taaattctgg
    45121 aaacacgctt gttaaaggcg ttcgtttttc tgccagagtc atcagtaata ttcattatgc
    45181 atgggtatgg ttactctctt tatttcgccc aagtcttcgc aaaaatcttt tagttatcaa
    45241 acttttgctg catgacatcg ggcttacaga aaatgattta aaaaaaatca actcccccac
    45301 tttgatcatc gtgggaaaaa aagatgtaat caagctaaaa cattctttgt atatagctaa
    45361 aactatacca aaagcttcct ttgtgcttgt gaaagaacaa ggacatgaat tagctagaaa
    45421 agatcctgaa cgcttcaatc gagaagttct tcaatttctt tctgaaacat aactattagg
    45481 aatagaaggt gatttatttg ttaaaaaata ccatacaatg gctgaaaaac cacctaggac
    45541 tgttcaaaac aatctttttg atttctgtca ttgtcattat tgtcggtgaa ttgatgtcca
    45601 tcggtaaaac tctatctatc cagcaattag gagaaacgtt tgccactata cctgtatgga
    45661 aaagcggact aatgctattg attggtctta tctctgtgtt acctatggtt ggttatgata
    45721 ttattttgaa tcggatgctt gaacaaaagc agaatcctcg ttacctgttt gagacaagct
    45781 ggctgatcaa tacgatcaac aatattgccg gtttcggcgg gtttgttagt gtggggcttc
    45841 gctctgaact atatggacaa aagaaagaga gcagaaacgt gatccaagca ttatcgaaag
    45901 ttttcttgtt tttgatggct ggactttcta tttacagtct gctttctttt ttacttgtag
    45961 tcttcacgcc agttgctcct tttttgaagc aatattggat atggttgatc ggcggcggtc
    46021 tatattttcc tgtcgtcttt ttatttacta ctttcaaaaa gaaaggattc cttggtggta
    46081 cctcacttaa aactcaagga cagctattgc tagtttcatt gttggaatgg accggtgtcc
    46141 tgtttagttt cctttctgtt ggttatttaa tggaaatccg gattgatctg tggcaaacaa
    46201 ttccattatt cattgctgct tcagtgatag gaatcgtgtc tatgattcca ggagaaattg
    46261 ggagtttcga tgtaatgatg attatcgggt tgtccgctat tggtgtgcca agagaaatag
    46321 tcgttgtgtg gatcttgctc tatcgcctgt tctactacat cattccgttt ttgattggaa
    46381 tcgtcttttt cttcaaaaat atcggttcca cttttgatca gcgttattct ggtatcccta
    46441 aacaattagc aacagaaatt gcgcataaaa tcgtggttgt cttattatac ttttctggaa
    46501 tcatgctagt actttctgcc actatcccgc aagcttttac agagtttcgc tggcttcata
    46561 gtttgaaccc attgaaattt cattttatta tccaatttcc tagtatacta ttgggatttc
    46621 ttttaatcat tatgggcaga gggatcgcag cacgtgtgaa acgagcatat ttgcctacaa
    46681 tcttcttgat tgttctagct ttactttatg ttttattaag tgattttagt ttcacaccgg
    46741 tggttttctt gtctattctg cttctgatca ttcttgcttc taaaaacgaa ttatttcggg
    46801 aacaattgat ctattcatgg gagtggcgta cgatcgatgg aatcattatt ggtgcactgt
    46861 ccttgcttta catcgttatt ggggtataca atctgccgga tttccctcat cggcgtcacc
    46921 attttatttc ctttttctta tttccttctg aaaagatttg gttttcggga ttgttggcca
    46981 tcatcgctgt tagtttcatg atcgttctat ttgttcattt ccttcaagga gaaaagaaac
    47041 agattggcga agcctttaat gaagaaaagg ccctgaagat ccttacaact tatggaggaa
    47101 actccgatag tcaattgatc ttcttaaaag ataagcggat gtttgcctat gaaaaagacg
    47161 gtgaaccaac tgttcttctc caattcgctt gcttcaataa taaatgtatt gtaatgggtg
    47221 atccttctgg taagaaagaa gattttccag aagcaatcga agcttttatc gaagaaacag
    47281 atcgactatg ctatttacca gttttctacg aaacaagcga agagattgtt atgattttgc
    47341 atgaattcgg ctacgatttc attaagatgg gggaagaagc ttatgtagac ctgaatagtt
    47401 ttacaacttc agggaaaaaa atgaagggca ctcgtgctgt cttgaatcgg atcgaacgag
    47461 aaggatttac atttgatgtc ttacaaccac cattttctac tgagcaaatg agtactttca
    47521 aaaatatctc tgataattgg ttgggttcac gaaaggaaaa agggttttct ttaggctttt
    47581 tctctgaaga ttatctacaa agagcgccta ttgcagttgt caaaaatacc caagaagaaa
    47641 ttgtcgcttt tgcaacgatc atgcctactt acacgaacaa taaagtagga acgattgatc
    47701 tgatgcgata tgattctaaa aaagcacctt ctggcagtat ggatttcttg ttcttgcatt
    47761 tgtttgccta tatgaaagaa gaacatatcc aatggttcaa tttagggatg gcccctcttt
    47821 caaatgtcgg aacttccaga aagagttttt tacaggaaag gattgcatac ttggtttacg
    47881 agtttggttc tcatttttat tctttccatg gattaagaga atataaaagc aagtacgcta
    47941 caaactgggt ctcacgttat actctatatt ctagagatag ttggattgca tatgttatga
    48001 ttgctttgct gattattgat aatgcgccag ttgagcagac acaaggtaga ataagtggtt
    48061 tgaaaaaatg gatacgaaga aagtattaaa aactgcatac cgatagatga acactctcat
    48121 gatgaataaa agagactgaa gtaaaacgaa agttcatgct tctacaatct cttcttatac
    48181 aattgaagaa caaagagcgg tccaaacaga aatcctgttt ggaccgctct tttattttaa
    48241 acatttttca ttaccaaaat attcgagtcg cgtttcttat gcttcgatct ctgtaacgat
    48301 acctgaacct actgtccgtc cgccttcacg aattgagaat gtcgttccgt tttcaacagc
    48361 gattggatgg atcaagtcaa catcaatcgt cacgttgtca ccaggcatga ccatttctgt
    48421 atcttctggc aatgtgattg ttcctgtaac atcagttgtg cggaagtaga actgtggacg
    48481 atagttgttg aagaatggag tatgacgtcc accttcttct tttgtcaaca cgtacacttc
    48541 tgctttgaat tttgtatgtg gagtaatgga acctggttta gcaagtactt gtccacgttc
    48601 gatatcgtca cgttggatcc cccgtaacaa cacgcctacg ttatccccag cttccccgta
    48661 atctaacgtt ttacggaaca tttctacacc tgttacaact gctttttgtg tttcaggttt
    48721 gatccctacg atctctacct catcaccgac acgaacagca ccacgatcaa tacgacctga
    48781 ggcaacagtt cctcgacctg taattgagaa gacgtcttcc actggcaata gtaatggttt
    48841 atctgtatca cgttctggtg ttgggatata ttcatctact gtatccatca attccataat
    48901 agcagcttca gcatctggat cgccttgcaa tgcttttaat gcggaacctt tgatcacagg
    48961 agtgtcatcg cctgggaaac catattcgct caataactcg cgaacttcca tttctaccaa
    49021 atcgatcaat tcttcatcat cgactaaatc aactttgttc aagaaaacaa tcaggtattt
    49081 tacaccaact tggcgtgaca ataaaatgtg ttcacgtgtt tgaggcatcg gaccgtcagt
    49141 tgcagaaaca actaagattg caccatccat ttgtgctgcc cctgtaatca tgtttttcac
    49201 atagtccgcg tgtcctggtg catcaatatg cgcgtagtgg cgtttttctg tttcatattc
    49261 tacgtgtgcg gtattgatcg taatcccacg ttcacgttct tctggagctg catcaatact
    49321 agcatagtct tgaggatttg ctaggccttt tttgcctaat actgtagtga tcgcagcagt
    49381 taaagtagtt ttcccatggt caacgtgtcc aatcgtacca atgttaacgt gtggtttact
    49441 tctgtcataa tgttcttttg ccataattta caaacctcct aaataatata gatcactgaa
    49501 aaatttcagc tctcaccttt ttattatagt ctttttttga ctaaatcaaa aagaatacgt
    49561 ccgacttact ttttgtaaga ttcgaactaa gcttattata cgtcaatatt ggtcaaagtc
    49621 aactaagagc actcgtctgt cttatacgcg aaaaaagtac cttttataaa taaaaaaatg
    49681 tgttttttga gaaaaacttc aagatagtcc ttaactttct tttgaagcaa taagaacaaa
    49741 atgaggaaaa gtttaaaatt cagctgttgc caacaacttt caatagacga aatcttctat
    49801 ttcgttaata ataaggaaag aggtgaagta catgaaaaaa ttaattggcg tacttgtcgt
    49861 tttaggcata tttctcggcg gaagttttgc agcttatcat tatttttacg gcggcgaagc
    49921 ttattataca aaaatcacga cgaatggcga aatgtcagct acccaagcag ataacggaga
    49981 gaaattcacg acttatacct acaagcaagc ggcttataat aaagatggtg aaaaaaaaca
    50041 ggtgacgctt cgcgaagaaa gagaacatcc attaaagatg aatgcgtatc ttaaactcaa
    50101 agtcaatcct cgtaaaggtg tattaagctg ggaagaaata aaggcttctg aagtgcctaa
    50161 aaatgcggca gaaaaaatcg ataattagta aatggtctta aaattttatt agataaaaag
    50221 aggctgggac agaagcgttt aactccaaga aataagaagg agttgcttct gcttccgccg
    50281 tttatacgtg tttagagcgt gagacaaaag tgttctttac ttttgtctca cgctcttttt
    50341 ttgttatatt cgtcttttcc gatccttctc ttgacacaat tcatttaact gatcactggt
    50401 acttgaacac ctaatattct agtcattttt ataaacgatt caatacttca tccacatttt
    50461 tgatcatcac ggatatcgta ccatccggat tattcacaaa ttcaatcaaa tctgggttgc
    50521 gatatacatc tactggtacg atcagttcga tcccgtttga tagcttgaat ttttgttttc
    50581 caaatttttt ctcagaaatt tcttgtactt cttttacagg aggtgcttct gggacaaatc
    50641 cttgctcttg tacttcttct ttaaaagcca tttttgccgt gatgttttcc ttgaagactt
    50701 tttccgcaat catctcatga tccaaccgac ctttttcttc tatcgtatca tagacagctt
    50761 ctttcaaatc agccatgata tcaaattctt ctgtctcaaa tttttttcca agatgcttgg
    50821 ctactttttg gatcactttt acattttctt ctaaagaagg tgcaggaaca ctttcgatca
    50881 ctcttccaga aaaataaagc tcttttttgc cagaaaactc atattttttt tcaattaatt
    50941 cgtaggtcca atcagtcaaa ttcacagcga atgcttcatc tgctttttgt gttttcgccc
    51001 ctagaattgc tcgattcaaa atcaagcggt tgtcgatccc tgcttcgtct gcttcaacaa
    51061 agtgagtgta agcctcacga taattgactt tcaataaaga taagtacatc actgtatcta
    51121 attcatacaa gacaacaaat acatctgcac taggtgcttc ttcactttct tggtagatat
    51181 cgaaccaccg ctgaacgatt gcttcacttg cttccacaaa attttcttga gcgattttaa
    51241 gtgattcaac gatcatgctt tcttctgcta gttgtccagt ttttgtttga gcagaagaga
    51301 ttttttggat cttcttttga agaaaatcac gaatatattc ttttgtcaga tccagctctt
    51361 tttgtgaaaa gactggagaa ccagtttctc tgtcaataat atgcagaatt gcttttttta
    51421 aatagatatc cattttctca ttcccttctg tcttagttta cggaaaaaaa atcaaaaata
    51481 ccagaatcaa aatcattttc ttttaaacaa aaatttcaag agtagaaaca aaatggattc
    51541 tttttttcga aaaatgcgct acacttatag ttgaacgaat aaaaaaggag ctgaaagtat
    51601 gaattcatta acaagcactt atcgtctatc aaatggttac gaaatcccgg tagtaggatt
    51661 cggcacatgg caaacacctg atggggatgt cgctgtttcc tctgttaaag aagcgctggc
    51721 tgcaggttat cgccatatcg atactgccca aggatacaag aatgaagaaa gcgtcggcca
    51781 agcgattaag gaaagtggaa ttcctagaga agagatattc ttgacaacaa aattatggaa
    51841 tgcaaaccac agctatgaac ttgtgatgtc ttcttttgaa gaatcattga agaagctcca
    51901 aacagattat ttagatctgt ttttgatcca ctggccaaac cctgttgctt ttcgtgataa
    51961 ttgggaacaa gcaaatgcag atacatggcg agcatttgaa gaactgtatg aagcaggtaa
    52021 aatcaaagca atcggtgtga gcaatttctt accccaccat ctagatacac tagcaaaaac
    52081 agcaaaaatt atgccgatgg tcaatcaagt tttccttgca ccaggcgaat tacagacaac
    52141 tgtagttgag tatgcaaaaa aacatgatat gatcctcgaa gcatatagtc cattaggcac
    52201 tggtaaaatc ttcgatgtgc ctgaaatgaa acaaatcgct gaagcacatg acaagacgat
    52261 tgcacaagtt gctttgcgtt ggtcgctgca acacgaattc cttcctcttc ctaagtcagt
    52321 gacaccaagc agaatcaaag aaaatactga attatttgat tttgaattaa cagaagaaga
    52381 aatgaaacaa atcgatcagt tagatggtgt agtcggcaaa gcaaaagacc cagatactac
    52441 ccaattttaa gtcgaaaggt gattttatgg atccaatcga acgcttgaat tctctctcgg
    52501 aagaagttac ccagactttt cattccgatt ttgtcttttt gatcgatgca gagaaaatcc
    52561 aacattttcc tgcaagaaac tggacacatg atcaaatcat cgaagaactg aaaaaacggt
    52621 tcgatcattc gctaatggtc aaaccctggc acgaacatga agtcatttat tcacctgaac
    52681 tacctgtttt tgccttgata ccgaaaaaat agaaagaatg gaacggatta tgtatatata
    52741 cataatccgt tccatttttt atttttcttt caaaaaacgg gaaaatacgc aaatttttct
    52801 gttgtaattt gcgtatacgc aagttttttt gcattactcc ttttcatttg gctgtttttt
    52861 tcttataatc gaaagggtat gagcgaagga gagaacatat gaagaaaaaa cagaaacaaa
    52921 aattattaaa tcaattccgt ccttcattgg atggtgtaag aggacaatta ttccgttctc
    52981 tagaagaaga gagcttgcga cgttatggtt tgccgttaca agtcatgctt gatcccaaaa
    53041 accgtcaaat cttaacgatc ggattagctg ggaaaacaaa tgaagataca cggatcaacg
    53101 tgccaatcga tgacaacttc aatactgtat taaagagaat tcgttcagga gaaaacggga
    53161 ttttcgaacg attccgtgac aatcttctta ttgaaatcgt gtcttactgg aatgatcaac
    53221 gattgaaaaa cgatgaacca actgcgcaag ctgttgcgac accagttaca gaagaaacag
    53281 tcagtgtgcc agaagaaaaa acggaaaaac caaaagcgga cacaactgaa aatacacgct
    53341 caactgatac gaatgccgct ttaagttttg ctgatttttc aaaagccgtt gctgagtatc
    53401 ctaaatttta cacagaacaa aatgaacatg aagtagttat taatgaaaaa aatgctgatg
    53461 aacctcgtaa attagcaact atttctatga ctactgaaaa tgagttcgtt atcgaaaaag
    53521 cactcgaacg gaaatacaaa gtcaaattga ctttgattcc tttgatcgaa caatttgcag
    53581 cgacagcgat tactgatcga taaaaattct atttgtcata aaaggctggg atttaaaatc
    53641 ccagcctttt tagtcatata ataatttcta cagcaagtaa aaagaaattc cttctaacat
    53701 caggctcaaa tatcagcttg acctgtccaa caaatcacct atgatcctac aatgttaggc
    53761 gacttctctt ctacctgaag atatcttgga gttgcctgat ttcttaagat gcctaacctt
    53821 aactataaaa aattctaata ataaacatat tttctgatag agaaaaaa
//
LOCUS       DAZAOD010000010        53263 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000010 DAZAOD010000000
VERSION     DAZAOD010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.010"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            329..1057
                     /locus_tag="ACHDPO_000651"
     CDS             329..1057
                     /locus_tag="ACHDPO_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3368307.1"
                     /translation="MESSSKGKSLYYQLVDVLKERIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELETQGYIYRRHGKGTYVSDLSDKSSDLAGAYSFTEEMRELGRVPNTV
                     ILEFKQMEANKKVAKNLNINLGETVFKLKRLRLADDEPLMVERSYLPAKLFIGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDADPLRIADGAPVLYLSRTTYNVKN
                     EIIEYTDSVARADQFHYKIRHVRK"
     gene            1075..2268
                     /locus_tag="ACHDPO_000652"
     CDS             1075..2268
                     /locus_tag="ACHDPO_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFN3368308.1"
                     /translation="MFELSKDKLKELGAEITTREIKQQPQLWKETAEILAQNQEKLAL
                     FFDQIKKAANGKRVRVIFTGAGTSQYVGDTAVPYLNEYGDNDHFIFHSFGTTDIVSSP
                     KEFLFPDEPTLLVSFARSGNSPESVATVKIANEQIKTLFHLTITCAKEGQLAKNAATD
                     ERNYLLLMPEKSNDAGFAMTGSFTCMLLSALWVFDQTAVEKKESYLQQLIRTGEDLIS
                     RDQEIQKLLPKSFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVIGFVNNQPYTRNYDLDILEEIKDDQITTSVIAIAQPGNIDFTGTSLLLE
                     ASISLPDAYLALPMIMTAQIIALDTSIKVANKPDTPSPTGTVNRVVKGVIIHEYVNKG
                     ETKDE"
     gene            2261..3256
                     /gene="lacD"
                     /locus_tag="ACHDPO_000653"
     CDS             2261..3256
                     /gene="lacD"
                     /locus_tag="ACHDPO_000653"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFN3368309.1"
                     /translation="MNEEKIAAMKSLSTKEGIISALAIDQRGALKKMIKALGKEPTAQ
                     QITEFKELVSAELTPYASAILLDPEYGLPAAKARHQEAGLLLAYEKTGYDATTPGRLP
                     DLLADWSTLRLKEQTADAIKFLLYYDVDEDPEINHLKHVFIERLGSECAGEKRPFYLE
                     LVSYDAKTNDSTSLEYAKIKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVEGYSDG
                     EIAYSKKEAAAFFKEQSDATPLPFIFLSAGVSTALFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGREGAIEWLRTQGRQNIESLNKVINENATPWFDKVKEDSVTAK"
     gene            3253..4194
                     /locus_tag="ACHDPO_000654"
     CDS             3253..4194
                     /locus_tag="ACHDPO_000654"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HFN3368310.1"
                     /translation="MITTVTMNPSIDIAYTLDELRIDQVNRVKTVNKTAGGKGLNVAR
                     VLHLLADDVLATGLVGGQHGAYIKEQLDQSGITHQFLPIKGETRDSIAILHGVNQTEL
                     LESGPVVTEEEQHKFTEHFARLMETTDIFTISGSLPQGFSKSYYAELLALTNKKGTRV
                     LLDTSGQTLLEVLEGKEKPFLIKPNLEELGELVHQTISSATSLDEIQSLLDHPLFEGI
                     NWIVLSLGAKGAIAKVGRHFYQVTIPKIAVVNPVGSGDSTIAGLAHALSKSYTIEETL
                     AFAMACGMANAQQEKTGWIDPVKVDYFRGEINVRKIR"
     gene            4240..6006
                     /locus_tag="ACHDPO_000655"
     CDS             4240..6006
                     /locus_tag="ACHDPO_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase family protein"
                     /protein_id="HFN3368311.1"
                     /translation="MTRFEIKEEFLLDGQPFKILSGAIHYFRVHPTNWERSLHNLKAL
                     GFNTVETYVPWNLHEKEEGTYDFSKILDLSHFLELAQSLGLYAIVRPAPYICAEWEFG
                     GLPAWLLTKECRIRSADPRFMKYVKRYYQTLLPKIVPHLVTHGGNVLMVQVENEYGSY
                     GEEKAYLRQVKKYLEEGGIDVPLFTSDGPWQATLRAGILIDDDVFTTGNFGSKAKENF
                     ADMAQFFEAHGKKWPLMCMEFWDGWFNRWKEPIIKRDPEELADAVKEALQIGSINLYM
                     FHGGTNFGFMNGCSARGAIDLPQVTSYDYDAPLDEQGNPTEKYFALKRMMAENFPEMQ
                     QMEPWIKETIVKKGINLKEKVSFFATLDTISKPIHSTYPQTMEELGQNTGYLLYRTTI
                     KKDAVNEKLRIIDGRDRVHVFLDEEKQAIQYQTEIGETIPLTLEKEDHQIDLLFENMG
                     RVNYGHKLLADTQRKGIRTGVMSDLHFITEWTQYCLPLETTEHIDFSKKWEAGQPAFY
                     RFEAELSEIGDTYLDLSEFGKGIVWVNGTNIGRFWEVGPILSLFVPEGLFRKGQNEIV
                     IFETEGRFSEVIDFVKEPIEKS"
     gene            6023..6502
                     /locus_tag="ACHDPO_000656"
     CDS             6023..6502
                     /locus_tag="ACHDPO_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFN3368312.1"
                     /translation="MAIIGVRIDGRLIHGQVANLWTTKLNIGRIMVVDDEVATNAIEK
                     SGLKLATPAGVKLSILPIEKAAANILAGKYDSQRVLIVAKKPDRILALVEKGVPIKEL
                     NVGNMSQTDETRSITKSINVVDADVEVFKKLDQLGVHLIAQMVPNDKAEDFMSLLIK"
     gene            6515..7405
                     /locus_tag="ACHDPO_000657"
     CDS             6515..7405
                     /locus_tag="ACHDPO_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFN3368313.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDQHVETMNYKAIERNFLMGALPWALSRMVPVFLAL
                     AFGGGLVQNVVAVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHISYLILGFT
                     ITALLATVFSNVQLLGTSVASVVKDFPGTFNSLPMLAVALIGLALATISYKNDQKNDQ
                     HPVVSQQSQSDEGEIEDDEI"
     gene            7392..8201
                     /locus_tag="ACHDPO_000658"
     CDS             7392..8201
                     /locus_tag="ACHDPO_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFN3368314.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDDTPELKEMMKTHTQFFNTSNFFNTIITGIDLAIEEKEGVSSKETVSGMKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPVGILIWILAQVAVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKLLPAGIVGGVYWMLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            8217..8621
                     /locus_tag="ACHDPO_000659"
     CDS             8217..8621
                     /locus_tag="ACHDPO_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3368315.1"
                     /translation="MSRQLVLISHGKFCEELKNSTEMIMGPQENIYTIPLLPEDGADT
                     YKERFLSVTAPLKDYVVLCDLLGGTPANTVSKLIMEGETIELYAGMNLPMVIEFINSQ
                     MIGAEPDFIGSGRESIVSVNQVIAGMGDDEEE"
     gene            complement(8802..9740)
                     /gene="yidC"
                     /locus_tag="ACHDPO_000660"
     CDS             complement(8802..9740)
                     /gene="yidC"
                     /locus_tag="ACHDPO_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFN3368316.1"
                     /translation="MNKWKNWLLGSGLVTIMLFLSGCVRMDSNGNPDTSGIIYRILVH
                     PMGQAITYLVENFNWSYGWAVILMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     ATQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESTFYGIDLGNPSLVLVAIAGIAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGIFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTPAEPAKQTKKQVQAPKNNAKNGRNAGKQQKRK"
     gene            complement(10074..11156)
                     /locus_tag="ACHDPO_000661"
     CDS             complement(10074..11156)
                     /locus_tag="ACHDPO_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFN3368317.1"
                     /translation="MTKNLIVRGAPQEYEIKENAWDSLPEHLYKRHIDNVLILHGKTS
                     WKAVKDVFPDLSITKIFEYYGGECTDPLADSFVSLCKKKDFNGIIAVGGGKVADLGKL
                     IAYKTNLPIIILPTLAATCAAYTPLSVVYNEEGVMLRYDMFPKANDLVLIDPKIILHS
                     PREMMIAGIGDTLAKWYESHAIISQLTIKPIEVQVAEFAALRCREILLEKSAEAMEAM
                     DQQKINQAFIDVVETNILLAGMVGGFGDDYGRTAGAHSIHDAMTVLPDSHQQLHGNKV
                     AYGILVQLMIENKLAEIEHLLPFYHHLNLPTSLADMGLHLTESDYQAVAERACLPDEM
                     IHFMKETITPALVVQKMKELEQVTQG"
     gene            11298..12749
                     /locus_tag="ACHDPO_000662"
     CDS             11298..12749
                     /locus_tag="ACHDPO_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFN3368318.1"
                     /translation="MKKGINILLVALMFLLVFLPVKVQGAEKDEIYERIKQSGELVVG
                     LSADYAPYEFHANVDGKDKIVGFDVSIAEKIAKDMGVKLKVEELGFDALLGALKTGKI
                     DLVISGMAVTEERLQEVDFSDPYFVVQQKVLVRKEDKNKFKTTADFSGLAVGAQKQTT
                     QEELVKNELTGAELTSLQKVPDLINNLLNEKVEGVVLEQPVAEAYAQQNKKVALTPVK
                     FAQGEKTTAIAMSKNTPELKNHVNASIKTINDDGLLKDYQKQANQLMFQDDQSFLQKY
                     GPYYLIGTKYTILLAFVGVLFGMVFGSLLALMKLGKNKFLKALAIIYIEYVRGTPLLV
                     QIFIVYFGTGVLGLDLSKLVAGCIAVSLNSAAYVAEIVRAGINAVNKGQMEAARSLGM
                     DQKEAMRFIIFPQAIKNILPALGNEFVTIIKESSVVSVIGVSELIFQTGVVQGASFKP
                     FLPYVLVSLIYFVLTFSISRILALVERRMGLNA"
     gene            12742..13464
                     /locus_tag="ACHDPO_000663"
     CDS             12742..13464
                     /locus_tag="ACHDPO_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFN3368319.1"
                     /translation="MLNVKKLSKSFGENEVLKSIDLSVKEGEVVVIIGPSGSGKSTIL
                     RCMNLLEEPTSGEIFFKGQNITAPDSDINQIRQKMGMVFQSFNLFPHMNVLENLTITP
                     VKIKKEDPKKAKEHALSLLNQVGLKEKVDSYPTSLSGGQQQRVAIARALAMNPDVMLF
                     DEPTSALDPEMVGEVLAVMQDLAKKGMTMVVVTHEMGFAKEVADRVIFMADGIIQEEG
                     TPKEIFENPQNSRTQDFLNKVL"
     gene            13484..14635
                     /locus_tag="ACHDPO_000664"
     CDS             13484..14635
                     /locus_tag="ACHDPO_000664"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFN3368320.1"
                     /translation="MDKSKIARRFQQPAENLLMNIAILAKEKEDIIDLSIGDPDLITD
                     PTIIEAAYTDVKNGATNYTAPDGSKEFLSTVVDFYQKKYGLSVECNQVRATVGAMHGM
                     YLVLQALLDPEDEVIIHEPYFSPYREQVILSGGKPVFVPTYEEKGFQLDVEDLKAAIT
                     DRTKVIVINSPNNPTGAVFSESTLKKIAEVAIENELYIISDEIYEDFAFKEKFVPMAR
                     FAPDNTITVSGVSKGFAMTGWRLGYMIAPAYINQIAGLINENITYSAPTASQRGAIYA
                     LKHYEQLVPPVVEVFKERLAYIEKRVAEIPYLSLSSVSGSMYAFINISKSGLDSVTFV
                     EEVLEKSGVLFVPGKAFGETIGDNYIRLAATQPLEILGEAFDRLAKLNF"
     gene            complement(14983..15258)
                     /locus_tag="ACHDPO_000665"
     CDS             complement(14983..15258)
                     /locus_tag="ACHDPO_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFN3368321.1"
                     /translation="MNKIKMNVQGRVQSVGFRYMTKIVADQLGITGTVKNEDDGSVTI
                     EAAGDDEAIKKFVEEVKRSPSPSGRVQYVDLQENPMMEDRKKFVVIG"
     gene            15366..16130
                     /locus_tag="ACHDPO_000666"
     CDS             15366..16130
                     /locus_tag="ACHDPO_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFN3368322.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKGEYLLEGFHLIEEAVAS
                     NAKVNELFITQRGLTEWASWLEENQALSVTLVSEEVMATVSDLPTPQGIMAVVEAEKR
                     EIPNFEGGWLLLDNVQDPGNVGTMIRTADAFGLSCVVLGKGTADVYSTKVLRSMQGSN
                     YHLPIIQEDLTKLLPILKEQGFITYGTELNEEAVSLNDIQTTENYAIVMGNEGQGVRP
                     EVLALTDKNVYIPIQGNAESLNVGVAAGIMLYHFSV"
     gene            16254..16757
                     /locus_tag="ACHDPO_000667"
     CDS             16254..16757
                     /locus_tag="ACHDPO_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFN3368323.1"
                     /translation="MTEKWREDEEYMSYINDLLETDAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYKLAKKWGGDARATARAGLLHDLFYYDWRTTKFDEGTHAYVHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMTASMKQKWQRY
                     FGKEQSI"
     gene            17022..17669
                     /locus_tag="ACHDPO_000668"
     CDS             17022..17669
                     /locus_tag="ACHDPO_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFN3368324.1"
                     /translation="MEKTIKPYQYYFIKREVEQLLSAYSSVNDPKTVQTVQALAAEKI
                     HEVLGHPNTAVNEFMEKVLDVTLKKEKAERLLEELKVIVLPFIQPTKPQIDKLFRKVK
                     KLKQPDWNQLDLREHTYIGWNDPGSQKKFMIYYEEEKLKGISGTLSPTINKGICSICQ
                     RTSNVSLFLSTTKTGSDGTYTKKGNYICHDSDQCNQQLVQLAPFYEFTERVKRER"
     regulatory      17712..17779
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            17830..19098
                     /locus_tag="ACHDPO_000669"
     CDS             17830..19098
                     /locus_tag="ACHDPO_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFN3368325.1"
                     /translation="MENRLPDPLKVIIYMIKWLLITAILGIFMGSLSAFFLTSLTDVT
                     AIRLEHPWLLFLLPISGGLFAYLYTTYGGNSSRGNNLVIDQGNGGNEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALAENFARWLKLNKIEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEALFPSFFAALFANFVTESFNVKHTHYQMGAIPAWDPS
                     LFFKLLLAGIAFGIIGWLFSRSIVWLKAWYAKRIPHPVLRNFIGGAVVVLVVVILQTQ
                     RYLGLSLPLLQDAFNGSAHPYDFLGKLGFTVLSLGAGYQGGEVTPLFEIGATLGATLA
                     PILHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGGQAASYFFMICLISFMCSGN
                     SGIYSAQKVEVKKGILFLPILGRISRQKEK"
     gene            complement(19275..20477)
                     /locus_tag="ACHDPO_000670"
     CDS             complement(19275..20477)
                     /locus_tag="ACHDPO_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFN3368326.1"
                     /translation="MNLTRDLIFLVIYILGMSGILYWRKRQSDPALFFYCGTWTFMMM
                     VTYFVVLEVFYHTFYFLIPLLFFSIFAFFYFKEKRRLINGVLFNTFLIVFGGYLGWLL
                     IETQNIFIGGLLALIGIPILILLAIGIYILIIFLFWNGVVVMKKESRSLANLLTLLLG
                     VALTIFLILDYTLVHWLPQWANALFAVIPFIFAYLLIVFFNFMTVSILYQFNRPRYNQ
                     DYIVVLGAGLIDGERVSPLLAKRINKAIAFYWAQSKATLNPPVLLMSGGKGTDEKVAE
                     AIAMKQYALEKGIPERDILVETNSTTTLENMLFSKEIMDQQMNGPYRAIFTSNNYHIF
                     RAGLYARQAKLNANGIGAKTALYYLPNAILREFIAILVLHKKRHLIICGLMIGFAVFS
                     ALILKFAQ"
     gene            21004..21729
                     /locus_tag="ACHDPO_000671"
     CDS             21004..21729
                     /locus_tag="ACHDPO_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTC domain-containing protein"
                     /protein_id="HFN3368327.1"
                     /translation="MNKKRFKRIERKFALTYDQAKYLKTLFPKQVVRDKYSDHFISSL
                     YFDTNDHHFLKEITTEKSYREKFRIRKYGDPQDISPIYLEIKRKFQGMTDKRRIKLAH
                     HELDDMLENIELAETTFSNLEEEYIFNEIQWLFRRLALEPKVYIYYLREAFVNRDSED
                     LRITFDQNIHYRLMNLTTWEHCTEDNLVAPEIDVLMEVKTTGEIPEWLQVGLDRMGKK
                     EIKFSKYKQVYKRYIQEDPLYVQ"
     gene            21719..22393
                     /locus_tag="ACHDPO_000672"
     CDS             21719..22393
                     /locus_tag="ACHDPO_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HFN3368328.1"
                     /translation="MFNSVLKNEPSQLTLDDFFLCMVVSILLGILIAYTHMYQNNCTK
                     NFMFALIGLPTLVHTVILLINGNLGTGIAVLGAFNLVRFRSAQGNSRDIFSIFWATSI
                     GLATGTGYIVYALFVSSIVAAIQVIIFTLPIKNKHTVFNTEKTIKLKVSKSLFLSSII
                     EEKIAEYTENCNLKKVKINKETCSLHYIVKVKTSMLEKELVRTIMDHPEVISITVGMD
                     KSNKLL"
     gene            complement(22681..22965)
                     /locus_tag="ACHDPO_000673"
     CDS             complement(22681..22965)
                     /locus_tag="ACHDPO_000673"
                     /inference="COORDINATES: protein motif:HMM:NF024076.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 family protein"
                     /protein_id="HFN3368329.1"
                     /translation="MRQKCFLLLSHSQKVKPIFWLSIWDGFFKVSFHFPEKTREKLVT
                     LSLSEGTKEKIKTLQANGNKRKHLSVIFDVDHLEQLADIYQLAEFKKQNG"
     gene            complement(23259..24566)
                     /locus_tag="ACHDPO_000674"
     CDS             complement(23259..24566)
                     /locus_tag="ACHDPO_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFN3368330.1"
                     /translation="MFKKNTRFIVLLASLILCITSFLPSATVQADDAFKINAKAAFAV
                     DAESGKILYDQDGEKTMGIASITKIIGLYIVLEQIKEGKLSWEDKVAISDYAEKLSVV
                     PDLSNVPLHKENDYTVKELVDSAFIQSANASMVALAEKVAGSESKFLELMKKQLKDWG
                     IKDATIVNASGLNNSYLGENRPENTGETDENQLSAKDVAIVARHLILDYPEVLKITST
                     TNQTFGENTQSPVEMVNWNWMLPGFVNYHEGVDGLKTGTTDFAGACFVGTINKDGRRI
                     ITVVLNADNHEENPSARFNETSRLMDYCYDNWSEKELGKANASIPSLKDIKVKDGKET
                     SVNVALKSPVKVWVENGMDTGKLTITPTIDKKKVTDDQVTAPINKGTTVGSATIQLAD
                     DKLGYLEANQEPSTDIITTSTVEKANIFVIGWRHVTDFFSNLF"
     gene            25055..26161
                     /locus_tag="ACHDPO_000675"
     CDS             25055..26161
                     /locus_tag="ACHDPO_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368331.1"
                     /translation="MAKKEKELLSQLTSEGTKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKITSLLDDPSFWRSATTSVAVIVSPEQVFIHRLGI
                     PVDDQYYVSDLPYLLAIIKNGHFNYSYYLLGLNRDSMKLYEVTNKQVKEVALPEDAPR
                     DVVTALGSELTGGGLNYASNGSEGTTFHGVNPKDEEVEIDWVNYYQAVDDYLKDTFEN
                     PEKWPIFLFALPENQTMFKKVAKNPYYRSDVAISASPAQLSLKEIEAGAKKLSQELAV
                     KEASDYNKLLDKKFIDQLVDIIPAAKEGKISHLFIATSNLADGFGEDPETEYDRRQVL
                     NELADNVITNGGQVFILEQKDAPDEKSLVAILRY"
     gene            26752..26952
                     /locus_tag="ACHDPO_000676"
     CDS             26752..26952
                     /locus_tag="ACHDPO_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFN3368332.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            27099..29888
                     /locus_tag="ACHDPO_000677"
     CDS             27099..29888
                     /locus_tag="ACHDPO_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFN3368333.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIEAGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSSHTGMDTSRFIYHVLEEMKENPEPLDLSLEIIDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIMEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPGQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHAFFADVAHRGTGFLARNQSFYKQDFVRFLQKKIKQSNFLIVNHAFLVQETQRKEP
                     LLPASPYLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICVAEGLMNLVSSKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAMDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLLDFQAAMLPSTVWYPRYDHILYIGGTLKIGP
                     NRQYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLEAALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAIDEI
                     YQDIHEFLKKNEEGS"
     gene            29935..30462
                     /locus_tag="ACHDPO_000678"
     CDS             29935..30462
                     /locus_tag="ACHDPO_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFN3368334.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            30483..31673
                     /locus_tag="ACHDPO_000679"
     CDS             30483..31673
                     /locus_tag="ACHDPO_000679"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFN3368335.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            31713..33011
                     /gene="asnS"
                     /locus_tag="ACHDPO_000680"
     CDS             31713..33011
                     /gene="asnS"
                     /locus_tag="ACHDPO_000680"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFN3368336.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            33945..34619
                     /locus_tag="ACHDPO_000681"
     CDS             33945..34619
                     /locus_tag="ACHDPO_000681"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFN3368337.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWREDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQKAGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            34616..34957
                     /locus_tag="ACHDPO_000682"
     CDS             34616..34957
                     /locus_tag="ACHDPO_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368338.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVGQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            34987..35346
                     /locus_tag="ACHDPO_000683"
     CDS             34987..35346
                     /locus_tag="ACHDPO_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFN3368339.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     AFLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            35870..37951
                     /locus_tag="ACHDPO_000684"
     CDS             35870..37951
                     /locus_tag="ACHDPO_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFN3368340.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNELIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            38262..39728
                     /locus_tag="ACHDPO_000685"
     CDS             38262..39728
                     /locus_tag="ACHDPO_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFN3368341.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            40013..40511
                     /locus_tag="ACHDPO_000686"
                     /pseudo
     CDS             40013..40511
                     /locus_tag="ACHDPO_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
     gene            40585..41025
                     /locus_tag="ACHDPO_000687"
     CDS             40585..41025
                     /locus_tag="ACHDPO_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFN3368342.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQKGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            41038..41247
                     /gene="copZ"
                     /locus_tag="ACHDPO_000688"
     CDS             41038..41247
                     /gene="copZ"
                     /locus_tag="ACHDPO_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFN3368343.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            41247..43433
                     /locus_tag="ACHDPO_000689"
     CDS             41247..43433
                     /locus_tag="ACHDPO_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFN3368344.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            43453..45624
                     /gene="copB"
                     /locus_tag="ACHDPO_000690"
     CDS             43453..45624
                     /gene="copB"
                     /locus_tag="ACHDPO_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFN3368345.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(45736..47907)
                     /locus_tag="ACHDPO_000691"
                     /pseudo
     CDS             complement(45736..47907)
                     /locus_tag="ACHDPO_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(47897..48649)
                     /locus_tag="ACHDPO_000692"
     CDS             complement(47897..48649)
                     /locus_tag="ACHDPO_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFN3368346.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            complement(48646..48969)
                     /locus_tag="ACHDPO_000693"
     CDS             complement(48646..48969)
                     /locus_tag="ACHDPO_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368347.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            complement(48983..49858)
                     /locus_tag="ACHDPO_000694"
     CDS             complement(48983..49858)
                     /locus_tag="ACHDPO_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3368348.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            50185..51474
                     /locus_tag="ACHDPO_000695"
     CDS             50185..51474
                     /locus_tag="ACHDPO_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368349.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            51548..52117
                     /locus_tag="ACHDPO_000696"
     CDS             51548..52117
                     /locus_tag="ACHDPO_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFN3368350.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(52293..52469)
                     /locus_tag="ACHDPO_000697"
                     /pseudo
     CDS             complement(52293..52469)
                     /locus_tag="ACHDPO_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            52548..53246
                     /locus_tag="ACHDPO_000698"
                     /pseudo
     CDS             52548..53246
                     /locus_tag="ACHDPO_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
BASE COUNT        17390 a         9315 c        11236 g        15322 t
ORIGIN      
        1 aatcctactt tatttagaga aagccatttt tatttacata gtagtctatt aggcccattt
       61 gcttgtcgat agtagaaata gccacagatg tataaagaat attttttctt tacttctcta
      121 gaccatttag ctgaatcttt gccaagattc agcttttttt tgttttttat ttgtcaactg
      181 gtatttttga ggtatctttt gataccagtt ctaaattacc ttgaaacctt gttataatag
      241 cttttttacg ccaaaaaccc tttgacaaat gaggaatatg tgggtattct tgtgttgtgg
      301 ttataaccag taaagaagag gtatttttat ggagagctca agtaaaggaa aatcattata
      361 ttatcaacta gttgacgtat tgaaagaacg tatcgaaaca cagatgacac ctcatgacaa
      421 attgttatct gaaagagaac tttgtcagca ttatggagtg agtcggacaa cggttcgcct
      481 tgctttgcaa gaattagaga cgcaagggta tatttatcgc cgacacggaa aaggaacata
      541 tgtgtctgat ctatcagata agtcgtctga tctggcggga gcgtatagtt ttacagaaga
      601 gatgagggaa ttgggacggg tgcctaatac agtcatcttg gaattcaagc aaatggaagc
      661 aaacaaaaag gttgccaaga atctaaacat caatttaggc gaaacagttt tcaaattgaa
      721 aagacttcgt ttagcggatg acgaaccatt gatggtggaa cgttcttatt tacctgcaaa
      781 actatttatt ggtcttgatc tgccattact tgaaagtaag ccattgtatg atgtgttttc
      841 tcaggattat gaacagcaag tccaattagc agatgaagaa ttttatgcaa gtatcgttca
      901 aaagaaagat gctgatccgc ttcgtatcgc tgatggtgcc ccggtattat atctaagccg
      961 aacgacctat aatgtgaaaa atgaaattat tgaatatacg gatagtgtag cgagagcaga
     1021 ccagtttcat tataagatcc gccacgtccg aaaatgattg agagggaaaa caacatgttt
     1081 gaactatcga aggataaatt aaaagagttg ggtgcggaaa taactacgcg agaaatcaaa
     1141 cagcaaccgc aattatggaa agaaacagct gagatattag cacagaatca agaaaaatta
     1201 gcattgtttt ttgaccagat aaaaaaagca gcaaatggca aaagagttcg agtgattttt
     1261 actggtgcag gcacatcaca atatgtcggg gatacagcag taccttattt aaatgaatac
     1321 ggtgataacg atcactttat ttttcatagc tttggtacga cagatatcgt gtcttcacca
     1381 aaagaatttc tatttccgga tgaaccgaca ttactggtgt catttgcacg tagtggaaat
     1441 agtccagaaa gtgtggcaac agtcaagatt gccaatgaac aaatcaagac attgtttcat
     1501 ttgacgatta cttgtgctaa agaaggtcag ttagcaaaga atgcagcgac agatgaacga
     1561 aattatcttt tactgatgcc agaaaaatca aatgatgcag gatttgccat gacaggaagt
     1621 tttacgtgca tgttgttgag tgcgttatgg gtattcgacc aaactgccgt tgagaaaaaa
     1681 gaaagttatc ttcaacaatt gatcagaact ggagaagatc taatttcacg agatcaagaa
     1741 atccaaaaat tattgcctaa gtcatttgaa cgtatcgcct atcttggttc aggaagtttg
     1801 gctggtgcaa cgagagaagc acaattgaaa atattggaat tgacagccgg taaagtggca
     1861 acgatctttg attcttctat gggcttccgc catggaccaa aatcgttttt aaatagcgaa
     1921 acacttgtta ttggttttgt taataaccaa ccgtatacaa gaaattatga cttagatatt
     1981 ctagaagaaa taaaagatga ccaaattacc acgagtgtca tcgcgatcgc ccaaccagga
     2041 aacatcgatt tcacaggtac aagtcttttg ttagaagctt cgatcagcct acctgatgcg
     2101 tatcttgcct tacctatgat catgacagcc caaatcattg cgctcgatac gtcgataaaa
     2161 gtagcgaata aaccagatac accatcgcct acaggtacag tcaatcgagt ggtcaaaggt
     2221 gtcattatcc atgaatatgt gaacaaaggg gaaacgaagg atgaatgaag aaaaaattgc
     2281 agctatgaag agtttatcaa caaaagaagg aatcatcagt gcattggcaa ttgatcaacg
     2341 cggtgctttg aaaaagatga tcaaagcgtt aggaaaagaa ccaacggcgc aacagatcac
     2401 tgaattcaaa gaattagtat cagcagaatt aacgccttat gcttctgcta ttttactaga
     2461 tccagagtat ggattgccag ctgctaaagc cagacatcag gaagcaggac tacttttagc
     2521 ctatgaaaaa acgggttatg atgcgacaac tccaggacgt ctgcctgatt tattagcgga
     2581 ttggtctacg cttagattaa aggaacaaac agccgatgcg atcaagtttt tgctttatta
     2641 tgatgtagat gaagacccag agatcaatca tttgaaacat gtatttatcg aacgtttagg
     2701 cagtgaatgt gcaggtgaaa agcgtccgtt ttatctagaa ttggtttcgt atgatgccaa
     2761 aaccaatgac agcacttcat tagaatatgc gaagatcaaa ccgcataaag tgatcgagat
     2821 gatgaaagaa ttttctgatc ctaaatataa agtggatgta ttgaaagtag aagtgccagt
     2881 caatatgaac tatgtagaag gttattctga tggtgaaatt gcgtatagta aaaaagaagc
     2941 agcggcattc ttcaaggaac aaagtgatgc aacaccgtta ccatttatct tcttgagtgc
     3001 aggggtttcg actgcattgt tccaacaaac attgatcttt gctcatgaat ctggttcaac
     3061 attcaacggt gtgttatgcg gacgtgcgac ttggaaagat ggagtcaaag catatgttga
     3121 aaatggtaga gaaggtgcga ttgagtggtt gagaacacaa gggcgacaaa atatcgaatc
     3181 gttgaataaa gtgataaatg aaaacgccac cccttggttt gacaaagtaa aagaagattc
     3241 ggtgacagca aaatgatcac gacagttacc atgaatcctt caattgacat cgcttacacg
     3301 ttggatgaat tacggatcga ccaagtcaat cgggtcaaaa cggtcaacaa aacggctgga
     3361 ggaaaaggct tgaatgttgc tcgtgtcctt catttattag cagatgatgt tttagctact
     3421 ggattagtcg gcgggcagca tggagcatat atcaaagaac aactcgatca atcagggata
     3481 acgcatcaat ttttacctat caaaggggaa acgagagatt cgattgctat tttacatgga
     3541 gtgaatcaaa cagaactatt ggaaagcggt cctgttgtga cggaagaaga gcaacataaa
     3601 tttaccgagc attttgcacg actaatggaa acaactgata tctttacgat ttcgggtagt
     3661 ctgcctcaag gattttctaa aagttattat gcagagttac ttgccctaac gaataaaaaa
     3721 ggaacacgag tattgttaga tacttctggt caaaccttgc ttgaagtctt ggaaggcaag
     3781 gaaaaaccat ttttgatcaa acctaatttg gaagaattag gagagttggt ccaccaaaca
     3841 atttcttcgg ctacttcgtt agatgaaatc caatcattat tggatcatcc gctttttgaa
     3901 ggaatcaatt ggatcgttct ttcgctaggc gcaaaaggag caatcgctaa agtagggaga
     3961 cacttctatc aggttacgat tcctaaaatc gcggtggtga atcctgtggg gtcaggagat
     4021 tcgactattg caggcttagc acatgctcta tcaaagagct atacgattga agaaacactt
     4081 gcgtttgcga tggcctgtgg gatggcgaat gcacaacaag aaaaaacagg atggatcgat
     4141 cctgtgaaag tcgattattt taggggggaa atcaacgtca gaaagattcg ttgattataa
     4201 aattagaaag cggtttctaa aaacgaggag gaaatttgct tgactagatt tgaaataaaa
     4261 gaagagtttt tgttagacgg tcaacctttc aaaattttat ctggtgccat ccattatttc
     4321 cgagtgcatc cgacgaattg ggagcggtca ttgcacaatt tgaaagcgct tggatttaat
     4381 actgtggaaa cctatgtgcc ttggaatctc catgaaaaag aagaaggaac ctatgatttt
     4441 tcgaaaatat tggatctttc ccattttcta gagttagcgc aatcccttgg attatacgca
     4501 atcgtacgtc cagcccctta tatttgtgca gaatgggaat ttggtggctt gcctgcttgg
     4561 ctattgacaa aggagtgccg tattcgttca gcggatcctc gcttcatgaa gtatgtcaaa
     4621 cggtattacc aaacgctact acctaaaatc gttcctcatc tagtcactca tggtggcaac
     4681 gtcttaatgg tgcaggtaga aaatgagtac ggttcgtatg gtgaagagaa agcatacctg
     4741 cgccaagtaa aaaaatactt ggaggaaggt ggaatcgatg taccgctatt cacttctgat
     4801 ggaccttggc aagccacatt aagagcaggc attttgattg acgatgatgt ttttacgaca
     4861 gggaattttg gctcaaaagc aaaagaaaat tttgcagata tggcccagtt ttttgaagca
     4921 catggtaaaa aatggccgtt gatgtgtatg gaattttggg atggctggtt taatcgttgg
     4981 aaagagccga tcattaaaag agatccggaa gaattagcgg atgcagtcaa agaagcatta
     5041 cagatcggca gtatcaatct ctatatgttc catggcggaa ccaattttgg gtttatgaat
     5101 ggctgttcag ccagaggcgc gattgatttg ccgcaagtca cttcctatga ttacgatgca
     5161 ccattggatg agcagggaaa tccaacggaa aaatattttg ctctgaaacg aatgatggca
     5221 gaaaattttc cagaaatgca gcaaatggaa ccatggataa aagaaacaat cgtcaaaaaa
     5281 ggaatcaact tgaaagaaaa agtcagcttt ttcgcaacac tggataccat cagcaagccg
     5341 atccactcga cctatcctca aacaatggaa gaattgggtc agaatactgg gtacctattg
     5401 tatcgaacaa cgatcaaaaa agatgcggtc aatgaaaaat tacggatcat cgacggacgt
     5461 gatcgggtcc atgtttttct cgatgaagaa aagcaagcga ttcaatacca aacagagatc
     5521 ggtgagacca ttccattgac acttgagaaa gaagaccatc aaattgatct attatttgaa
     5581 aatatgggac gggtcaacta tggacacaag ctgctagctg atacgcaaag aaaaggaata
     5641 cgtacaggag tgatgagcga tcttcatttt atcacagaat ggacacagta ttgtttacct
     5701 ttagagacta cagaacacat cgatttttca aaaaaatggg aagcaggtca accagcattt
     5761 taccgctttg aagcggaact gtcagaaatc ggtgatactt atttggacct tagtgagttt
     5821 gggaaaggga tcgtttgggt gaatggcacg aatattggtc gtttttggga agtaggacca
     5881 attctttcac tgtttgttcc cgagggttta tttagaaaag gacaaaatga aatcgttatc
     5941 tttgaaacag aaggtagatt cagtgaagtt atagattttg tcaaagaacc aatagaaaaa
     6001 agttagaaaa ggagaatgga tgatggcaat tattggagta agaattgatg gacgtttgat
     6061 acatggacaa gtggcaaatc tttggacgac aaagttgaat attggtcgga tcatggtcgt
     6121 agacgatgag gtagcaacaa atgcgatcga aaaaagtggg ttaaagttgg caacgccagc
     6181 tggagtcaaa ttaagtattt tacctattga aaaagcagcc gcaaatattt tagcaggtaa
     6241 atatgattct caacgagtgc tgatcgtagc gaaaaaacca gatcgtatct tagcgctagt
     6301 agaaaaaggt gtaccgatca aagaattaaa tgtcggcaat atgtcacaaa cagatgaaac
     6361 acgttccatc acaaaatcaa tcaatgtcgt agatgcggat gtagaggtct tcaagaaatt
     6421 agatcagctt ggcgttcatt tgatcgctca aatggtgcca aatgacaaag cagaagactt
     6481 tatgagtctt ttaatcaaat aggaggaatg attcatggat attcaatggt ggcagatatt
     6541 attattaaca ttatatgcag ggtatcaaat tttagatgaa ttacagattt attcttcaat
     6601 gagcgcccca gtttttgcag gattatatgc tgggttagta atgggtgatt taaaagcagg
     6661 tttaatcatt ggtggaagta tgcagttgac tgttttaggg gtagggacat ttggtggtgc
     6721 atcaaaaatc gatgccaact ctggaacgat cttagcaaca gctttctcca tttctctagg
     6781 gatgaaccca gaacaagcga ttgcggccat cgcggttcct gtagcaagtt tgatgatcca
     6841 attagatatt ttggcacgtt ttgcgaatac gtattttgca catcggatcg atcaacatgt
     6901 ggaaacaatg aattacaaag caattgaacg gaacttcttg atgggggcat taccttgggc
     6961 actttccaga atggttcctg tattcttggc cctagcattc ggtggtggct tagtccaaaa
     7021 tgttgtggct gttttaaacg gcgacctaaa atggctagga gatggcttat ctgttgcagg
     7081 ggcagtctta ccagcagttg ggtttgcaat tttactacgc tacctaccag taaagaaaca
     7141 catttcttat ctgattttag gatttacgat cacagcgtta ttagcaacag tgttctcgaa
     7201 tgtccaattg ttaggaacaa gtgtggctag cgtggtcaaa gatttcccag gaacattcaa
     7261 ttcattaccg atgcttgctg tggcattgat tggtctagca ctggcaacga tcagttataa
     7321 gaatgatcaa aagaatgacc aacatccagt agtaagtcag caatcacaat ctgatgaggg
     7381 ggaaatcgaa gatgacgaaa tctaattata aattgaccaa agaagatttt aagcagatca
     7441 atcgtagaag tttgtttact ttccaattag gttggaacta tgaaagaatg caaggttcag
     7501 gttatctgta tactatcttg ccacaactta gaaaaatcta tggtgatgat acaccagaat
     7561 taaaagaaat gatgaaaaca catacgcaat tttttaatac gtctaatttc tttaacacga
     7621 tcattactgg gatcgatctt gctatcgaag aaaaagaagg agtctcttca aaggaaactg
     7681 tttctgggat gaaagcagga ttgatgggtt ccttcgctgc aattggtgat tctgtatttg
     7741 cggcattgat cccgaccata tttggagctt tagccgcaaa tatggcaaca gatggtaatc
     7801 cagtaggtat ccttatctgg atccttgctc aggtcgctgt catggtcttt cgttggaaac
     7861 aactagaatt tgcctacaaa gaagggattt ctctagttac cacgatgcaa tcacgcttga
     7921 ctgcattgac agatgcggct actttactag gagttttcat ggttggagcg ttagtagcaa
     7981 ccatgatcaa tgttaaattc tcatgggcac caacgattgg ggatgtaacg ttgaatatgc
     8041 aaaactatat cgatatgatc ttacctaaac ttttaccagc tggaatcgtt ggtggcgttt
     8101 attggatgtt aggtaagaaa aatatgacac ctactcgagc aatattcatc gtattgatcg
     8161 tatgtgtagc attatctgca ttaggtgtga tttcgaaata agggagaatt ggaaagatga
     8221 gtagacaact agtcttgatt agtcatggta aattttgtga agaactaaaa aacagtacag
     8281 aaatgatcat gggaccacaa gaaaatatct atacgatccc tttattgcct gaagatggcg
     8341 cggacacgta taaagaaaga ttcctctccg ttacagcacc attgaaagat tacgtagtgc
     8401 tttgcgatct gttgggtggg acacctgcaa ataccgtttc caagctaatc atggaaggtg
     8461 aaacgatcga actatatgct ggcatgaatt tgccgatggt catcgaattc atcaattcgc
     8521 aaatgattgg agcagaacca gattttattg gttcgggtcg tgagagtatc gtttcagtga
     8581 accaagtgat tgctggcatg ggagacgatg aagaagaata atcaagcaca acttcttgac
     8641 tggtgataca actggatata aatacggatg tataaagagg ccgtgtataa aaaagccaac
     8701 gtaccgcgaa atatagtttt ctatatttca cagtacgttg gcttttatcg tcataaaatc
     8761 agaaatgatc tgggtcgatc gaagaagcta gttacaaata actatttacg cttttgctgt
     8821 ttaccagcat tccgaccatt cttcgcattg ttttttggtg cttgtacttg tttttttgtt
     8881 tgcttcgcag gttcagcagg tgtgacatct ttacgaggcg tcaccacttg ttttggcgga
     8941 ttttgtttta attcttccgc aacttgcgct tttaatcttg gtttcatgat gacattcgta
     9001 atgaatgttt gtagacaact aaagatccca ccgactaccc agtaaagagt gacaccagct
     9061 ggggcactga tcgacatgaa gacgatcata gcgggtgata cgatcaacat cgtacgcatc
     9121 gttttctttt gttcttcagg gataccgata gttgagatat agccttgaag taaataagca
     9181 ataccggcaa tcgctactaa aactaagcta gggttaccta ggtcgatccc gtaaaaggtt
     9241 gattcacgga tgccttctgt atagcgagca gtgaaatata gcgcagaaaa gatcggcatt
     9301 tggatcagaa gcggtaaaca accgatacca ccagtcatac ttaagccatt ttcacgataa
     9361 acttgttgca tttcagcttg tgcagccatt tgttcttctc gagttgtcgc agctttcaat
     9421 ttttgttgcg tagcttcaac ttgtggtttc aatgcttgca tcttttcaga ttggatcatt
     9481 gtttttttcg attgactaat acctaatggc aaaatgatga tacgaacgat gactgtcatc
     9541 aagataacag cccagccgta ggaccaatta aagttttcca ctaaatatgt aatcgcttgt
     9601 cccattgggt gaaccaatat acggtaaatg attcctgaag tgtcagggtt accatttgaa
     9661 tccatgcgga cacaaccgga caagaaaagc atgatcgtga caagcccaga gcccaataac
     9721 caatttttcc atttattcat aaaatacttc ctcttttata atttttacac aagcttaact
     9781 atactaaaaa agcgctcata attcaatcaa cttcatagaa atttcataga aataaccgat
     9841 tggaggatca aaaaagacgc ttaatgttaa aaagaagaat ccagctaaaa atacttcagt
     9901 ataaagcata cttagcacct ccgttctcta aaataagatg agcaacggat atttccttga
     9961 aatcataatt ttagcgcaaa aaaaagaagt ggaatgtcaa ttttttccac ttcttttttt
    10021 ttaccattga gccgatccat aaaaaagctg actgccatgg tataaggggc taactatccc
    10081 tgtgtcactt gttctaactc tttcattttc tggacaacca gtgctggtgt gatcgtttct
    10141 ttcatgaagt ggatcatttc atcaggtaaa catgcacgtt cagctacggc ttgatagtca
    10201 ctttctgtta aatgtaaacc catatcagct aaactcgttg gtaagttcaa gtgatgataa
    10261 aacggcagta ggtgttcgat ttctgctaat ttattttcga tcatcagctg gacaaggata
    10321 ccgtatgcaa ctttgtttcc atgaagttgc tgatggctat cagggagtac ggtcatcgca
    10381 tcgtgaatgg aatgagctcc agctgttcgg ccgtagtcat cgccaaaccc accaaccata
    10441 ccagccaata aaatgtttgt ttccacgaca tcgataaaag cttgattgat tttttgctgg
    10501 tccatcgctt ccattgcctc tgcacttttc tctaaaagga tttcgcggca tcgtaacgct
    10561 gcaaattccg ctacttggac ttcgataggc ttgatagtta actgagagat gattgcgtga
    10621 gattcatacc attttgctaa ggtgtcacca ataccggcaa tcatcatctc gcgaggggag
    10681 tgcaaaatga tctttggatc gatcaacact aaatcatttg ctttagggaa catatcatag
    10741 cgaagcatca ctccttcttc attatagacc acactaagtg gagtataagc tgcgcacgtc
    10801 gcagctaagg taggtaagat gatgattggt aagtttgtct tataggcaat caattttcct
    10861 agatctgcta ctttcccgcc gccgactgca ataataccat tgaaatcctt ctttttgcat
    10921 aaagaaacaa aactgtcagc aagtggatcg gtacattctc caccataata ttcaaaaatt
    10981 tttgttattg ataaatctgg aaaaacatct tttactgctt tccaagatgt ttttccatgg
    11041 agaatcaaaa cgttgtcaat atgccttttg taaaggtgtt cagggagtga atcccatgcg
    11101 ttttctttta tttcatactc ttgaggggca ccgcgaacaa ttaaattttt tgtcatataa
    11161 aaaacttctt ccattatttt tttaaattaa tcttttttta ttataatagt tatgctagta
    11221 tattagcaag ttatttatga atatttattc ttttatagct tttctgatta cattattatt
    11281 caaaggtggc caaatggatg aaaaaaggaa taaacatatt attagtggcg ctgatgtttc
    11341 tactggtttt tttaccagta aaagtacaag gtgcagaaaa agatgaaatt tacgagcgga
    11401 taaaacaaag tggagaatta gtcgttggcc tatctgcaga ctatgcgccc tatgaattcc
    11461 atgcgaatgt ggatggtaag gataaaatcg ttggttttga tgtatccatt gccgaaaaga
    11521 tcgcaaagga tatgggtgtg aaactaaaag tagaagaact tggttttgat gcattattag
    11581 gtgcgttgaa aactggcaag atcgatttag ttatatctgg tatggcggtg actgaagaac
    11641 gtttacaaga agttgacttt tctgacccat atttcgtggt acagcaaaaa gtactcgttc
    11701 gtaaagagga caaaaataaa tttaagacga cagccgactt ttctggctta gccgttgggg
    11761 cgcaaaagca aaccacacaa gaggagttag tgaaaaatga actgactggt gcagagttga
    11821 cctccctgca aaaagttcct gatctgatca ataatttgct gaatgaaaaa gttgaaggtg
    11881 ttgtgctgga acaaccagtt gcagaagcat atgcccaaca gaataagaaa gtagctttga
    11941 ctccagtaaa atttgcgcaa ggcgaaaaaa ccacagctat tgcgatgtca aaaaatacac
    12001 cagaactgaa aaatcatgtc aatgcgtcaa tcaaaacgat caatgacgac ggcttgctga
    12061 aagattatca aaaacaagcg aatcaattga tgttccaaga tgatcagtcc tttcttcaaa
    12121 aatacggtcc gtattatttg attggaacaa aatacactat tttattagct tttgtgggtg
    12181 tattgtttgg aatggtcttt ggtagtttgc ttgcactgat gaaattgggt aagaataaat
    12241 ttttaaaggc attagccatt atttatatcg aatacgtacg gggaacacct ctcttagttc
    12301 aaatctttat cgtttacttc ggaacaggag tactgggatt ggatctatcg aaactggtag
    12361 caggttgtat tgctgtctcg ttgaatagtg ctgcttatgt agccgaaatt gtccgtgccg
    12421 ggatcaatgc ggtcaacaaa ggacagatgg aagctgcacg ttctttagga atggaccaga
    12481 aagaagccat gcgtttcatc atcttcccac aagcaatcaa aaatattctt ccagctctag
    12541 gaaatgagtt tgtcacgatc atcaaagagt cctcagttgt ttcggtcatt ggggtatcgg
    12601 aattgatctt tcaaacgggc gtggtacaag gtgctagctt caaaccattc ctaccatatg
    12661 tgttggtctc tttgatttat ttcgtgttga ccttcagtat ttcccgtata ttagctttag
    12721 ttgaaaggag aatgggtctg aatgcttaat gtaaaaaaac tgtcaaaaag ttttggcgag
    12781 aatgaagtct taaaatcaat tgatctttct gtgaaagaag gagaagtagt ggtgatcatt
    12841 ggcccttcag gaagtgggaa aagtacaatt ctacgttgta tgaatctgct ggaagaacca
    12901 acttctggtg aaatcttttt taagggacaa aacattacag cccctgacag cgatatcaat
    12961 caaattcgtc aaaaaatggg aatggtattt caaagtttta atttgtttcc ccatatgaat
    13021 gtactcgaaa atttgaccat cacacctgta aaaatcaaaa aagaagaccc taaaaaagca
    13081 aaagaacatg ctctatcatt attgaaccaa gttggtctaa aggaaaaagt ggacagttat
    13141 cctaccagtt tatctggggg acagcaacaa cgggtagcaa ttgctcgagc attagcaatg
    13201 aatcctgatg tgatgctttt cgatgaacct acatctgcac ttgatcctga aatggtcggt
    13261 gaagtgttgg cagtcatgca ggatttagct aaaaaaggga tgacgatggt cgtggtcact
    13321 catgaaatgg gttttgctaa agaagttgcc gatcgtgtga tttttatggc tgacggcatc
    13381 attcaagaag agggaacacc gaaagagatt tttgaaaatc cgcaaaatag tcgaacacag
    13441 gatttcttga acaaagtgtt gtaacaaaga tggaggaagt aagatggaca aaagtaagat
    13501 tgcacgccgg tttcagcaac cagcagaaaa tctgttgatg aatattgcta ttttggcaaa
    13561 ggaaaaagag gatattatcg atttatcgat tggtgatcct gacttgatca ctgatccgac
    13621 gattattgaa gcagcttata cagatgtaaa aaatggtgct actaattata ctgcgcctga
    13681 tggcagcaaa gaattcttgt caacggtcgt agatttttat caaaagaaat atggattgag
    13741 cgttgaatgc aaccaagttc gagctacagt cggagcaatg cacgggatgt atctagtttt
    13801 acaggcatta ctagatccag aggatgaggt catcatccat gaaccttatt tttcaccata
    13861 tcgggaacaa gtcattttat ctggaggcaa gcctgttttt gttcctacct atgaagaaaa
    13921 gggcttccag ttggatgtgg aagatttaaa agcagcgatt acggatcgta caaaggtgat
    13981 cgtcatcaat tcgccgaata atcctacggg agctgttttt tctgaaagca cgttgaaaaa
    14041 aatcgctgaa gtcgcaatcg aaaatgaact ctatatcatt tccgatgaga tttatgaaga
    14101 ctttgccttt aaagagaagt tcgtaccgat ggcgcgattt gcgcccgata atacgatcac
    14161 tgtcagtggt gtatcgaagg ggtttgcgat gactggctgg cgcttagggt acatgatcgc
    14221 accagcatac atcaatcaaa ttgctgggtt gatcaatgaa aacatcactt attccgcacc
    14281 gactgcttct caaagaggtg caatctacgc cttaaagcac tatgaacagc ttgtaccgcc
    14341 agttgttgaa gtattcaaag aacgattagc ttatattgag aaaagagtgg cagaaatccc
    14401 ttacttatct ttatcttctg tttctggaag catgtatgct tttattaata tcagtaagag
    14461 tgggctcgat tcagtaacgt ttgtggaaga ggttttagaa aaaagcggcg tactttttgt
    14521 ccctggaaaa gcgtttgggg aaacgatcgg ggacaactat attcgactag cagcgactca
    14581 gccattggaa atcttaggtg aagcctttga tcgtttagca aaactaaatt tttagataaa
    14641 actgtatatt tgaaaacagc tatgggtatc cattagaaca aagagggaaa atgatccttt
    14701 cgagagttgg cttgttgact gggcagcgtc aggatttgac aatgaaaaag tggtagtgga
    14761 aaatcaaagt cgattttcca ctaccataaa atattataga ctccatttta ttgaaccaaa
    14821 atttttgaag tcctcccgct tttacgtatg cctatcactg gttactaaac tcgctaataa
    14881 gaatgttttt ttgtcgatct aggatggaga gaggggcaaa ctttttcgat ctacatacag
    14941 acagtccgat ttttctgaca tttcctattc atttctagaa ggtcagccta ttacaacaaa
    15001 cttttttctg tcctccatca tcggattttc ctgaaggtct acatattgga cacgtccgct
    15061 ggggcttggt gatcgtttga cttcttccac gaattttttg attgcctcat cgtcgcccgc
    15121 agcttcgatc gtgacagagc cgtcatcttc atttttcact gttccggtga tccctaattg
    15181 atccgctacg atttttgtca tatagcgaaa accaacgctt tgtacacgtc cttgcacgtt
    15241 catcttgatt ttgttcattt tattcaccgt tctttctttt atttttaaat taatgatacc
    15301 gacttttttg ctactgaaca agtgcaatga tctaatccat ggtataatca gttgaggtga
    15361 aaaatgtgaa agagatccaa tcagcaaaaa atccaagaat caaagaatta aaaaaattac
    15421 ataagaaaaa atatcgtgaa gaaaaagggg aatatctgct tgaagggttt cacctgatcg
    15481 aggaggctgt tgcctcaaat gcgaaggtca acgaactttt tattacgcaa cgcggtctga
    15541 ctgagtgggc tagttggctt gaagaaaatc aggcgctttc tgttacacta gtatcagaag
    15601 aagtgatggc aactgtttca gatctaccaa ctccgcaagg gatcatggca gtggtggaag
    15661 ctgaaaaaag agagataccg aattttgaag gtggttggtt gttgctcgac aacgtacaag
    15721 atcccggcaa tgtagggaca atgatccgca cagccgatgc ttttggtcta tcttgtgttg
    15781 tactaggtaa gggaacggcg gatgtctaca gtaccaaagt attaagaagc atgcagggga
    15841 gtaactatca tttaccgatc atccaagagg atctaacaaa actattgcct atccttaaag
    15901 agcaaggatt tataacctat ggaacagaac tgaatgaaga agcagtgtcc ctgaatgata
    15961 tccagacaac agaaaattat gcgatcgtga tggggaatga aggtcaaggc gtacgtccag
    16021 aagtgctggc gctaacggat aaaaatgtgt atataccgat tcaaggaaat gcggagtctt
    16081 taaatgtagg agttgcagcg ggcatcatgc tttatcactt ctccgtatag ttaaggaact
    16141 attaagcttt ctgcattttg cgaaaacctc actagaatat tacgaacact agtggtatac
    16201 taagttcaat ttcaaagata aatggaattc aaaaaggtgg cagatcgata attatgacag
    16261 aaaaatggcg tgaagacgaa gaatatatgt cttatataaa tgatctatta gaaactgatg
    16321 cagtaaagaa attagcaaat tacacgcaac atgtccactc gacacgatta gagcattcaa
    16381 tcagtgtgtc ttactatagc tacaaattag cgaaaaaatg gggcggtgat gcaagagcga
    16441 ctgctcgagc aggcctttta catgatttat tttactacga ttggcgtacg acgaagttcg
    16501 atgaaggtac acatgcgtat gttcacccaa ggatcgctgt gaaaaatgct gaaaaaatca
    16561 cggagctttc agatctagag cgtgatatta ttttgaaaca tatgtgggga gcaacgattg
    16621 cccctcctaa atataaagaa ggttatatcg ttacttttgt ggataaatat tgtgcagtca
    16681 aagaagcagc tcaaccaatg acagcttcaa tgaaacaaaa atggcaacga tatttcggta
    16741 aagaacaatc gatttaaggt agttaactaa gtatttgacc cgagtatttt gaaaaaaatc
    16801 ctcgggtttt ttgtttagac attgactaat tggtcttttt agtgtttact ttgttgagat
    16861 gaaaaagtac ataaccaaca taaaaataaa gggggtgatg ataagatgcg atgtgtatct
    16921 tatttaaaag agtttgaggg ctttatctaa aggcactttg atagaaagat cacttttttc
    16981 ttcaaagtag ccgattttga aagaagaaag gactcaaagt catggaaaaa acaatcaaac
    17041 catatcaata ttattttatc aagcgagaag tcgagcagct gttaagcgcc tatagttcag
    17101 tgaatgatcc aaagacagtc caaacagtcc aagcattagc tgcggaaaag atccacgagg
    17161 tacttggtca tcctaataca gctgtaaatg aatttatgga aaaggtacta gacgtcactc
    17221 taaaaaaaga aaaagcagaa cgactattag aggaattgaa agtgatcgtt cttccattca
    17281 tacaaccgac aaaaccgcag atcgataaat tattccgaaa agtgaaaaag ttaaaacaac
    17341 cagattggaa tcaactggat ttaagggaac atacttatat tggttggaat gatccaggta
    17401 gccaaaaaaa atttatgatc tattatgaag aagaaaaact aaaagggatc agtggaacat
    17461 tatctcctac aatcaacaaa ggaatttgtt cgatttgtca aagaacttca aatgtttcac
    17521 tctttctttc taccacaaaa actggttcag atggaacata cacgaaaaaa ggaaattata
    17581 tttgtcatga tagtgaccaa tgtaatcagc agttggtaca attagctcct ttttacgaat
    17641 tcacagaacg agtgaaacgt gagcggtgat ttcattgtat ttttctgaaa aatatgctat
    17701 cttatttggt gaagtgaata ggtgatggtg ttcgccttta aacgttgatc gtaagataac
    17761 taatgacgcc tactaaagaa acggggctac cccttttttt agtaggcgtt tttttgagga
    17821 ggaaatgaga tggaaaatcg attacctgat ccattgaagg tgatcatcta tatgatcaaa
    17881 tggttattga tcacagcaat tttaggtatt tttatgggaa gtttatccgc attctttcta
    17941 actagtttga ctgatgtgac agctattcgg ctggagcatc cttggttact ttttcttttg
    18001 ccgataagtg ggggactttt tgcttatcta tatacgacgt atgggggcaa ttcttcccgg
    18061 ggaaacaatt tagtgatcga tcaagggaat ggaggaaatg aaaagattcc attacggctg
    18121 atcccactga ccttatttgg caccattacc acgcatcttt ttggtggttc tgttggtcgg
    18181 gagggtacag cggtccaaat gggcggggca cttgctgaga attttgctcg ttggctaaaa
    18241 ttgaacaaaa tcgagcgtga gattcttgtc atcagtggga tcagcgcagg ttttagctca
    18301 gtatttggga cacccttggc tgggacattg tttggattag aagtattggc aatcggaaaa
    18361 gtgagaaccg aagcactgtt tccaagcttt tttgcagcac tttttgcgaa ctttgtaacg
    18421 gaaagtttca atgtcaagca tacccattat caaatggggg cgattcctgc atgggaccct
    18481 tcacttttct tcaaattgtt gcttgcgggc attgcatttg gtatcattgg ctggctcttt
    18541 agccgttcga tcgtctggtt aaaagcttgg tatgcaaagc ggatccccca tccagtttta
    18601 cgcaacttta ttggaggagc agtcgtggta ctcgtagtag tgattttaca gacgcaaaga
    18661 tatctcggat taagcttacc tttattacaa gatgcattta atggaagtgc tcatccttat
    18721 gattttcttg ggaaacttgg ctttaccgtt ctatcacttg gcgcgggata ccaaggaggc
    18781 gaagtgaccc ctttgtttga gattggggca actttaggtg cgacattagc acccattctt
    18841 catgtatcag tacctttttt agcaggatta gggtttattg gggtgttctc tggagcaacg
    18901 aatacaccga ttgcttgctt tgttatgggg atcgaacttt ttggaggtca agcagccagc
    18961 tacttcttta tgatctgttt gattagcttt atgtgttcag gaaatagtgg aatctattct
    19021 gcgcaaaaag ttgaagtgaa aaaaggaatc ttgttcctac cgatccttgg aagaatctca
    19081 cgacaaaaag agaaataaaa agaggttggg acagaagtgt ttaactccga gaaataagaa
    19141 gaaattcacg aaaattgctt tttaaatttt tgtgaatttc gcttatttcc gaaggagttg
    19201 cttctgctcc caccgtttat tcggagttag agtctgtggc aaaactgatt tttagttttg
    19261 tcccacgctc ttttttattg agcaaatttg agaataagag cagaaaatac tgcaaagcca
    19321 atcattaagc cacagatgat aagatggcgt tttttgtgta agacaaggat ggcaataaat
    19381 tctcttaaga tagcattcgg taagtagtat agtgcagttt ttgcaccgat tccgtttgca
    19441 ttgagtttcg cttgtcgcgc atatagtcca gctctaaaga tatggtaatt atttgaagta
    19501 aaaatcgcgc gataaggccc attcatttgc tgatccatta tttcttttga aaacagcata
    19561 ttttctagcg tcgttgtgga attcgtttct actaaaatat cacgctcggg aatccctttt
    19621 tctaaagcat attgtttcat tgcaatggct tcagctactt tttcatcggt tccttttcct
    19681 cctgacatga gcaagactgg cggattcaaa gttgctttac tttgtgccca ataaaatgcg
    19741 atcgccttat tgatcctttt agcaagtagg ggagatacgc gttcaccatc aatcaagcca
    19801 gcgccgagaa caacgatata atcttggtta taccttggac ggttgaactg atacaaaatt
    19861 gaaacagtca taaaattaaa gaaaacgatg agtagataag caaaaataaa cggaatgaca
    19921 gcaaatagag catttgccca ttgtgggagc caatggacta atgtatagtc caatatcaaa
    19981 aagatagtca aagcgactcc taacaagaga gtcaaaaggt tggccaaaga acgggattct
    20041 tttttcatga ctacaacacc attccaaaat aaaaaaatga tcaaaatgta gataccgatt
    20101 gccaaaagaa ttaatattgg tatcccgatc aaagccaata acccaccgat aaagatattt
    20161 tgcgtctcta ttagtagcca ccctagataa ccaccaaaga caatcaaaaa cgtattaaaa
    20221 agtacgccat tgattaacct acgtttttcc ttaaaataga aaaatgcaaa aatactgaaa
    20281 aatagcaatg gaatcaaaaa ataaaatgta tgataaaaaa cttctaaaac gacgaagtaa
    20341 gtgaccatca tcataaaagt ccacgtccca caataaaaga atagagcggg atcgctttgg
    20401 cgcttgcgcc aatagaggat gcctgacatt cctaaaatat agataactaa aaatatcagg
    20461 tctctagtaa gattcattga atgaactcct ttcgatttgt aaattttttc ttaaaaaaga
    20521 tagcatcatt tagtagtaaa tatatcgaat atagaaaagt tagttactaa atagtcaatc
    20581 agttttttca cgacgtttct attataacga attatgttga aaaaagcttt tatcgaaaac
    20641 ataaatcttc aaattaacag attttttaga cctcgatcat gatgaagact tttgtagata
    20701 caaataactg taacattgaa aatgaatgcg aaaacgatat ttttttttat tggaaaatat
    20761 cggtcaagca ataaaccagt tgcataataa aatgttaacg gcaacaaaat ctgtggaagg
    20821 aatgaaccgg atgatttgat ggaaaaaaca agatagacaa gaagtataca tagtaaaacg
    20881 tggaacaagt aggccagaat gaaaaatcag tttttatcca ctcgcttttc tatacattca
    20941 ctgtcacaaa tataatcgaa agtaattcta ttttgagata aagtatttta taggagatag
    21001 tatatgaaca aaaaaagatt taaacgtatt gaaagaaaat ttgcattaac ttatgaccaa
    21061 gctaagtatt tgaaaacact atttccaaaa caggtagttc gggataaata tagtgatcat
    21121 tttatttctt ccttgtattt tgatacaaac gatcatcact ttttaaaaga aatcactaca
    21181 gaaaagtcct atcgagaaaa atttagaatc agaaaatatg gagatcctca ggacatatcg
    21241 cctatctact tagagataaa aagaaagttt caaggaatga cagataaacg tagaataaaa
    21301 ttagcgcatc atgagctcga tgatatgttg gaaaatatcg aattggcaga aaccacattc
    21361 agtaatttag aagaagagta tatttttaat gaaatacagt ggttgttcag aaggttggca
    21421 ttggagccca aagtatatat ctattattta agagaagcat ttgtaaatag agattcagaa
    21481 gatttgcgaa tcacttttga tcaaaatatc cattaccgtc taatgaactt aacgacctgg
    21541 gaacactgta cagaagacaa tctggtagcg ccagaaatcg atgtgctgat ggaagtaaaa
    21601 acgacaggag aaatacctga atggttacag gtaggattgg ataggatggg taaaaaagag
    21661 ataaaatttt ctaaatataa acaagtctat aaaagatata tccaagagga cccgctctat
    21721 gttcaatagt gtcttaaaaa atgagccttc tcaactcaca ctagatgatt tctttttatg
    21781 tatggtggtg tcgattttgc taggcattct gattgcttac acccatatgt atcaaaacaa
    21841 ctgtacaaaa aacttcatgt ttgccttgat tgggttacct actttagtac ataccgtcat
    21901 tttgttgatc aacggtaact taggcacggg gatcgctgtt ctaggcgcat ttaacttagt
    21961 gcgatttcgg tctgctcaag ggaattcaag agatattttc agtatttttt gggcaacgtc
    22021 gattggttta gccacaggga cgggatatat tgtctatgca ctattcgtgt ctagtatagt
    22081 tgctgctatc caagtcatca tcttcacgct tccaatcaaa aataaacata cagtttttaa
    22141 tactgaaaaa acgatcaagc taaaagtttc taaatccttg tttctttcga gtattattga
    22201 agaaaaaatt gcagaatata cagaaaactg caatttaaaa aaagtaaaaa tcaataaaga
    22261 aacttgttcc ttacactata tagtaaaagt aaaaacgagt atgcttgaaa aagaattggt
    22321 tcgaacgatc atggatcatc cagaagtcat ttcgatcact gtaggtatgg ataaatcgaa
    22381 taaattattg tgataaccaa gaaagtactt aacaatgaag taagacccca gttccaaagt
    22441 ttagcgggga cacttcaata aagtactttc ttttttgtct tcagcaacta ctggtaaaac
    22501 tgagagcaag ctttcgtgag agtacagcga taaagatcaa cctccctttt tatctcgagc
    22561 aatttccttg caaggctgtt tcgttgatct taaacgagtt agcaacagtc aaagatgcga
    22621 tggccataaa aaaattgcat taagttggct ggtatctgat agctgggaat ctaaggaaga
    22681 ctatccattc tgtttcttaa attccgctag ttgatagata tcagccaatt gttccagatg
    22741 atcaacatca aagataaccg aaagatgttt ccttttattc ccatttgctt gaagagtttt
    22801 tatcttctct ttggttcctt cactcaatga gagtgtgact aatttctccc tcgttttttc
    22861 tgggaaatga aaggatactt tgaaaaatcc gtcccaaata gaaagccaga agatcggttt
    22921 tactttctga gagtgggaca aaagtaagaa acacttttgt ctcattcttt aaaaacgaat
    22981 aaacggtggg agcagaagca actccttcgg aaataagcca aaattcacaa aaatttgaaa
    23041 agcaattttc gtgaatttct tcttatttct cggagttaaa cacttctgtc ccaacctctt
    23101 gtattcacct tttgatagcc aagcttttcc atcattataa aaccgcaaat ttcaaaaaaa
    23161 aacgaacaat acaaaaagcg tattgctcgt ttttctcttc agtttctcac acctaaacga
    23221 cttttgtctc gacctctttt tggtgactat tcatgatgtt aaaataaatt actgaaaaaa
    23281 tctgtgacat ggcgccaacc aatgacaaaa atattagctt tttcaacagt agaagtggta
    23341 atgatgtctg tcgaaggctc ttggtttgct tccaaatagc ctaatttgtc atcagctaat
    23401 tggatcgttg ctgagccaac tgtagtgcct ttgttgatag gagcggtcac ttggtcatcc
    23461 gttactttct ttttatcaat tgttggagta atcgttaatt ttccagtatc cattccattt
    23521 tcgacccaga cttttacagg gctttttagc gcaacattga cggaggtttc ttttccatct
    23581 ttcactttga tgtcttttag gcttgggatg cttgcatttg cttttccaag ttctttttct
    23641 gaccagttgt cataacaata atccatcaat cgtgatgttt cattgaatcg ggcacttgga
    23701 ttttcttcat ggttatctgc atttaaaacg actgtgatga ttcgtcggcc atctttgttg
    23761 atcgttccga caaagcatgc acccgcaaaa tcagttgtgc cagtttttaa tccatcgaca
    23821 ccttcgtgat agtttacaaa accaggtagc atccagttcc aattgaccat ttcaaccggt
    23881 gactgtgtgt tttcgccgaa tgtttgattt gtggtactcg tgatttttaa gacttcagga
    23941 taatctaaga tgaggtgacg agcaacaata gcgacatctt tcgcagacag ttgattttca
    24001 tctgtttcac cagtattctc aggtcgattc tcacctaggt aagaattgtt taaacctgat
    24061 gcattgacga tcgttgcatc tttgataccc caatctttta gttgtttctt cattagctca
    24121 agaaatttac tttcactgcc tgcaactttt tcagctaaag caaccatgga agcattggct
    24181 gattggatga aagctgagtc aacaagttct ttcactgtat aatcattttc tttatgcaaa
    24241 ggaacattcg atagatccgg cacgacactt aatttttctg cataatccga aatggctacc
    24301 ttatcttccc aagataattt accctctttg atttgttcaa gtacgatata tagaccaatg
    24361 atctttgtga tggaagcaat tcccatcgtt ttttcgccat cctgatcata aaggattttt
    24421 ccactttctg catctacggc aaaggcagct ttggcattta ttttaaatgc gtcgtctgct
    24481 tgaacagttg cgctaggcaa gaaagaagtg atacataaga taagacttgc taatagtaca
    24541 ataaaacggg tatttttttt gaacatcttt gttctcctca tttttaaatt gattcttaca
    24601 acttagaata ttatcagaga gaacaaaagg tttcaatggt tctgaaaaaa accttataaa
    24661 gaacaagtct tattaatgaa gaatcataga aagttatctt ttgggttcat tgacacgaac
    24721 tttgactggc tgaacttcgg gttcggttag gcgtgatgct gcaaaaaggg cgcctgctga
    24781 gagtgcgacc aaactaaaaa tcatgaataa ttgcataaga tcacctcgtt cttttttgtt
    24841 tttttatagt atagcaagag agtttgaagc tactgttaag gaaatgagca tataattgat
    24901 gaaagtatga aaaaaatatg aagtaggaca acacaactaa aaatcgatca ggtatttctc
    24961 tggtagggat tcgttttatt gtattgataa aatgggatgt ggtagacttt atttacagat
    25021 acaaagaaat gattttttta ggaggggtac gtttatggca aaaaaagaaa aagaattatt
    25081 atcacaattg acttcagaag gtaccaaagg accgtttgtc acgattatgt taaacaccca
    25141 tgttgcgcat caagacgtag aaaaagatca aatcaaattc aagaattttg caaaggaagc
    25201 gaaaaagcgc tttgaaaaga aatactctga gcatgattgg tctccattcc aagaaaaaat
    25261 tactagtttg ttggacgatc cgtctttctg gcgtagtgcc acaacgagtg tagctgtcat
    25321 agtatcacca gaacaagtgt ttatccaccg tttgggtatt cctgtagatg accagtatta
    25381 tgtgagtgat ctaccttatt tattagcgat catcaaaaat ggacatttca actattcata
    25441 ctatttatta ggattgaatc gtgattcgat gaaattgtac gaagtaacga ataaacaagt
    25501 caaagaagtg gctttgcctg aagatgcacc aagagatgtc gtcactgctt taggatctga
    25561 actaacagga ggcgggttga actacgcatc aaatggtagt gaaggtacga cgttccatgg
    25621 agtcaatcct aaagatgaag aagtcgaaat tgattgggtc aattattatc aagcagtcga
    25681 tgactatttg aaagatacat ttgaaaatcc agagaaatgg cctatcttct tatttgcatt
    25741 accagaaaat cagacgatgt tcaaaaaagt ggcgaagaac ccttattatc gttccgatgt
    25801 tgcgatctca gcttcacctg cacaactttc attaaaagaa attgaagcag gcgcaaaaaa
    25861 actatcgcaa gaattagctg tcaaagaagc aagtgactac aataagttgc ttgataaaaa
    25921 gttcattgat caactcgttg atattatacc ggcagcaaaa gaagggaaaa tatcccattt
    25981 attcattgct acatctaatt tagcagatgg ttttggcgaa gatccagaaa cagaatatga
    26041 ccgccgtcag gtgctgaatg aactagcaga taatgtgatc acgaacggtg gtcaggtctt
    26101 tatccttgaa caaaaagatg caccagacga aaagagttta gttgcgatct tacgttattg
    26161 agtgaaaact accaaagtag atgaatggtc aggcgttgat agaagtgtat agctccgaga
    26221 gaaggagttt cctctgtttc agccgttgga ttcatcttga gcgagagaca aaagctagct
    26281 tttgtctctc gctcattatt tttgtgcttt agtcccattg gctttgcgag gggaagatac
    26341 ttttctcaaa aaaacgaacc ttgcagttga gagggggata gatgcgcata ctaattttta
    26401 tcagttaaaa aatgatgtgg atcattagag aattccaaag ttcgttcatc ctttttcaga
    26461 taataaattg aaattttttg caaaagtgaa aatagcaaat agaaattttc tgaatcttat
    26521 aggggtgatt tcgagaaaac gttcgtttat ttgcaaatat atcttctaaa taagagaata
    26581 aatacaaaaa aataaggaaa aactctggca attttgtaaa cggtatgata tagtaagaat
    26641 gtagtttttg ttcggtaatc tgtggtagct tgtttcaaat aaacatcttc cagatataca
    26701 ccattcaagt aattgcaaaa tatgtgttga tacacaagga ggatttttat tatggaaaca
    26761 ggtacagtaa aatggtttaa ctcagaaaaa ggatttggat tcatcactgc agaaaacgga
    26821 aacgatgtat tcgttcattt ctcagctatc caaggcgacg gattcaaaac tttagaagaa
    26881 ggccaagcag taactttcga cgttgaagaa ggtcaacgcg gacctcaagc aacaaacgtt
    26941 actaaagctt aatttaccta tattaaaaat aaaagtccag acatttatgt gtctgggctt
    27001 ttttgtcttt ttttccttaa aaagcgatga gagtattttt ctgcactttg tagtataatt
    27061 tcaaaagaac attagaggca ggagaagagg aagatatttt gaaaccaaga acttatgcag
    27121 tcgttgatat cgagacgact gggacgaatc caaaagaaga tcggatcatc caatttggct
    27181 gcgtcatgat tgaagctggt cggatcactt cacgtttttc gatcgatatt catccagggc
    27241 ggaagatttc aaaacaaatc cagcatttaa cagggatcac gaatcaacgc gtccaaaaag
    27301 cgccttattt tgaagatgtc gcccaaacga tttacaatct tttggcagac accatatttg
    27361 tcgcgcataa tatttatttt gattataatt ttttgaacca tgaactcatg cgatgcggac
    27421 ttcctagttt gaagataccg ggcatcgata ccgtagaact tgcacaaatt ttcttgccga
    27481 cggaaccaag ttttcgctta gctgatttgt cagaaagcct tggctttatt catgagaatc
    27541 ctcatcaggc ggatagtgat gccgaagtga caggtcagct tcttttactg atcgaagaac
    27601 gaatgaggaa attgccgatc atcacattag agcagattgc acgattaagt agccatacag
    27661 gaatggatac gagtcgtttc atttaccacg tgcttgaaga aatgaaagaa aacccggagc
    27721 cccttgatct ctcattagaa atcatcgatg ggctagcttt gcagaaaaaa gaagtggagc
    27781 tattcacatc cgtccattat ggcgagcgga catatccaag aaaaaaacaa gcaaaagaaa
    27841 aaatgtttgg taaaacactg atgtatcgaa aagaacagaa caggctgatg aatgctgtct
    27901 acgaccattt cacaaaagat gaatcaaaag atttgatgat cgaagcagct acaggaatgg
    27961 gcaaaacgat tggttatctg ttgcctttga gttatttggc tacacctgaa aaaccagctg
    28021 tcatcagcac cgtttcgctt gttttgcagc agcagatcat ggaaaaagac attccattac
    28081 tgaatcaatt gctagatcag ccgatacaac ctgtgattat caaaagctat cgccactata
    28141 ttgatttaca gcgttttaaa ggtacacttg tggaaccgcc gggacaaaaa caatatgctt
    28201 tgtaccaaat ggctgtctta gtttggctaa cacaaacgaa gaccggtgat ttggatgaat
    28261 tacatttaac caatctgaac catgcattct ttgcagatgt cgcgcacaga ggcactgggt
    28321 ttttagcaag gaatcagtca ttttacaaac aagactttgt gcgtttcttg caaaagaaaa
    28381 tcaaacaaag caattttttg atagtcaacc atgcattttt agtacaagaa acacagcgaa
    28441 aagaaccatt gcttccagct agtccttatt tgttgattga tgaagtgcat catttgccgg
    28501 aaattgctga aaaagtaaat gacaaacgac taagtattaa ctacttccat aaacaaattc
    28561 agcaactgga agagccgaat cagttatttg accgcataca aagttatttg ccgaaggaac
    28621 atgaagcctt gcgctggttg tcgatttatc gagaagaact ctctgcacta tgcgaagcgc
    28681 agatttgcgt ggcagaggga ttaatgaact tagtaagcag caagcaacct aacggacaat
    28741 atccagaaga agtcatgatg acaaaagaaa tgttggatca gctgccactg gaatctggaa
    28801 cagcaatgga tcatctgcaa cttttttatc aagagatcca acaactacaa tcacagatgc
    28861 gcttgacttt tgagattatc caagaaagtt ggaccaacca gatgcggatc gatttagcaa
    28921 gtttatatag cttatttgat caattagaca agcaatactt gctgatggac caatggctag
    28981 aagactggcg agatcatttg atccattggt tcgttcccgg gaatacagca cagcagatga
    29041 tttttcatct ccttgatttt caagcagcta tgttgccgtc aactgtgtgg tatcctcgat
    29101 atgaccatat tctttatatt ggaggaacac tgaagatcgg acctaatcga cagtatctct
    29161 ctaaacgact tggcattgaa gcagcacctc ttaaagtgat tgcttctcct tatgattatg
    29221 agaaacaggc aagaatctat gtgccgaaag aagcacctgc agtccatcaa gtcagcaatc
    29281 aagcatatat cgattattta gaagcagcac tcacaggatt gattgaacaa gaagatcggc
    29341 cgatccttgt tttattcact tctcatgatg ttttgcaaaa ggtatatcag aaaatgcatt
    29401 tgtctatgct agaaaaagga cgtgaaattc ttgctcaagg atttggcggg agtcgggaaa
    29461 aacttttgaa acgcttcatt ttgtcagaaa aaagcgtctt atttggtgct gacagctttt
    29521 gggaaggcgt agatttacct ggagatgctt tgcagattgt tgtagtcaca cgtttaccct
    29581 tcgacaaccc gttacgtccg atggtcaaag ctaggaatgc ttatctggaa tcagagggga
    29641 tcaatccttt ttatcaggaa tccgtgccta aagcagcttt gaagttacgc caagcattag
    29701 gtcgtttgat aaggacggag acagatcgtg gcgtattact tattttggat cggagattag
    29761 tcactgcaaa atatggtgca cgaatcatcc atgcattacc gaaaaaagta ccgataaaag
    29821 agctagctat agatgaaatc tatcaggata tccatgaatt cttaaagaaa aatgaagaag
    29881 gaagttaaag gtgccgtctt ttttcatcat taaaatctgc tataatgaaa aggaatgaag
    29941 ataaaggagc gacgaccctt gaagaaaaaa cagacaaagg aaaaaacgat taatcgcgtg
    30001 ttgcttggct tgatcgtatt tttattagcg gtcatcgtga tcagctcgat tttttacttg
    30061 cgttccagtc gtccggcggt ccaggcgaaa aaagaagcag tagaaatcgc aaagaaatat
    30121 gcaaatctcg aggaagccga tcatttttac tggtttactc gaaagaaaac gtacttttca
    30181 ttgacgggta cgaatgataa aggaaaagaa atcgccgtta tcattcctaa atctggtgaa
    30241 aaagtaaaag tattggatca aacaaaggga ctgactgaaa acgaagcaaa acagacaatt
    30301 gctgcggccc atcctgaaat ccaaatcgaa aaagctgctt tagggatgta tgatgatcag
    30361 cctgtgtggg aagtagtagg aaaagaaaca aatgggaaac tgaattatta cctgattggc
    30421 tttgaatctg gagatgaagt caagacaatc aagggaattt aaaaggtaaa ggaatgaatg
    30481 ggatggagtt atcaaaaaga acaaaacgat tagaaccgtc tgtcactttg gcagctgcgg
    30541 caaaggccaa ggcattaaaa gcaaaaggca gagatgtgct gagtttgact gtgggagaac
    30601 cggattttgc gacaccagaa aacatccaag aagcagcaat cgaagcaatc cgcaatggga
    30661 aagctagcta ttatacacca acagcaggaa tcccagagct tcgacaggca atcgttgatt
    30721 atctgaagaa aaactatgga cttgtctatg aaccttcaca aacagtcgta acagacggag
    30781 cgaaatttgc tttgtatacc cttttccaaa cgatccttga cccgcaagat gaagtcatca
    30841 ttcctgtgcc ttactgggtc agttacggtg agcaagtaaa actggcagaa ggacttcctg
    30901 tctttgtgaa aggggaagaa tccaatagct ggaaagttac tgttgagcag ctagaacaag
    30961 cacgttcaga aaaaacaaaa gccgtaatca tcaattctcc atcgaatccg actggaatga
    31021 tttatagcaa gaatgaactg caggcaatcg gtgaatgggc agtaaaaaat gatattttga
    31081 tagttgctga tgatatttat ggccgtttag tttataatgg caatgagttt actccaattg
    31141 caacgatttc agaagcaatc aaaaatcaga ccatcatcat caatggcgtg tctaaaacat
    31201 atgcgatgac aggctggcgc attggttatg cggtggggaa ttctgagatc atcaatggaa
    31261 tgattgctgt tgcttcccag tcaaccagta atccgacagc agtcagtcaa tatgcagctg
    31321 ttgaagcatt gaaaggcgag caagatacag tggaagaaat gcggaacgcc tttgaagaac
    31381 gcctgaatac gttatatccg cttgtggcag aactgccggg tgtttctctt gaaaagccac
    31441 aaggagcttt ttatcttttt cctaatgtaa aagaaacgct acgcatgtgt aaatatgaaa
    31501 atgtcacaca atgggtagaa gatcttttag aagaaacagg ggtagcgctt gtgactggcg
    31561 aaggctttgg ggcaccagaa aatgtccgca tgagttatgc cactgatcgc gctacgttag
    31621 aagaagcggt acgcagaatc aagcaattta ttgagagtaa aagtcaaaat taatcctgaa
    31681 gaaattcaag gaatataaaa ggagagtcat acgtggaaca aattcaaatc atcgattcga
    31741 aaaaccatgt gggagaaaca gtaacaatcg gcgcttgggt cgcaaataag cgatcaagcg
    31801 gaaaaatcgc atttttgcaa ttaagagacg gaacagcctt tttccaaggt gtagttgtaa
    31861 aaagcgaagt gccggaagaa gttttccaaa cagctaaaaa tctacaccaa gaaacatccg
    31921 tgttagtaac tggagaaatc cgtgaagaca gtcgttcaaa atttggttat gaaatcggaa
    31981 ttacaaatgt ggaagtggta agcgagagcc acgattatcc gatcacacca aaagaacacg
    32041 gaacagactt cttgatggat catcgtcatt tatggctgcg ttcttcaaga caacatgcga
    32101 ttatgcagat cagaaatgaa atcattcgtg caacgtatga attctttaat caacatcatt
    32161 ttgtcaaaat cgatccgccg atcttgactg gttctgcacc agaaggcact acggatctat
    32221 tcgaaacaaa ttactttgat caaaaagctt atttatctca aagtggccaa ttatacatgg
    32281 aagctgctgc tatggctttc ggaaaagtct tttcattcgg tccgactttc cgtgctgaaa
    32341 aatcaaaaac acgacgtcat ttgatcgaat tctggatgat cgaaccagaa atggctttca
    32401 ctcatcaaga agaaagttta gaagtacagg aacaatatgt agcattctta gtacaaaatg
    32461 ttttagatca ttgcgaatac gcattagatg tactaggacg agacaaagaa gtcttaaaaa
    32521 cttatacaaa attgccattc cctcgtatta cttatgatga tgcgatcgaa ttactgaaga
    32581 aaaatggatt tgatgacatc gaatggggcg aagactttgg ttcacctcat gaaacgttca
    32641 ttgcgaattc attcgaacag cctgtcttta tcctaaacta tccaaaagcc atcaagccat
    32701 tctacatgaa accacatcca acaagagaag acgtggtgat ctgtgcagat atgatcgcac
    32761 cagaaggtta cggtgaaatt attggtggaa gcgaacgggc aacagactat gatttcttgc
    32821 tagaacaaat ccgtaatcac ggtttggatg aaaaagaata ttcatggtat cttgatctac
    32881 gtaaatacgg ttctgttccg cactctggtt ttggtctagg ccttgaacga acagtcactt
    32941 ggattgctgg tatcgaccat gtgcgtgaag ctattccatt cccacgtttg ttgaaccgaa
    33001 tttatccata agaggttgtg aaatcagtgc cttgacctga gtattagaga aacaaaacgg
    33061 aaaaatagct tctcatattt tactgttttt tgagctaata tcgagggtca gctgattgaa
    33121 caccgtttat atcaagaggt tgtgcgtctg ccgttcagct ccgagtcaca aggagtaatt
    33181 tcaaaaaaac attttttcat gtttgatgac tattgtgact tgtgaccaag gagttggccg
    33241 gagagcaacg tttatttaaa aaaaagaact gcgaactctc gcagttcttt ttttttaaat
    33301 acgggataaa ggaagtttcc agcagataag agaagaaagc aaaagaaatt gctatttgat
    33361 tcacaaggtt ctataacgaa atcgcaatca atcaaacata tacaaagaag gttattcaaa
    33421 tggaaatctg atttgatgat gcttctgctg ttgaaataaa gcagcatcta gcacctgaaa
    33481 acaaactaat agtaacattc gaagatggag taggtccgta ttttcagcat gcaatgatcc
    33541 atatgtaagt tcaattcacc cttgaaatca tcggaccaga taaagttatg gccaatctat
    33601 cccaagcaat ctagaagaga tattagtaaa ggaacattta ctggaagtct tagatgagcc
    33661 tataaatata tgttctgatg gcgtcatcaa gtggtctgat tgacggaagc ttaggtgtga
    33721 tcgatctctc tggaccaaac aatgaaggaa tcaaggggaa tccagcacgt taagaaaaaa
    33781 atagcataaa aaactagaca cttgatgagc gttcattcaa ttgtttgaag ggactaggct
    33841 ggtgtcattt tttatacata tattttctct ttcgtcttga tagggcttat gggataatat
    33901 aaggaagaaa atcatcgttt tattcaaaaa ggagtttttg acaaatgaaa aaacgtatat
    33961 tatttatcgg tgacagcatt acagacgcag gaagagaccg agcagaagca actgatctag
    34021 gtaaaggtta tccacttttg attgccggaa aactaatctc ccaatatcca acgatggaat
    34081 ttgaatgcat gaaccgtggg ataggaggag acaaaattgc agatctgcaa gtacgctggc
    34141 gagaagattg tttagcttta caacctgact atgtatcgat tttgatcgga atcaatgata
    34201 cctggcataa tactagcgat caggctatat tcggaactga gaaatctgct cagcaatttg
    34261 aatccgttta tcgaaaatta ctaaatgaac ttcaaaaagc gggaatctgc aacatcatct
    34321 tgatggagcc gtttgtactt cctataaccg acgaccgtca tggctggcgt aaagacttag
    34381 accctaaaat ccaaattgtt cgtaaacttg ctaaggaata tggcgcattg ctggttcctt
    34441 tagatggcat attcaatgct ttagggattg cttatggttt ttcgaaatat acaagagaag
    34501 atggggtcca cccaacgatt ggcggacatg agatcattgc acaaagctgg atagatgcaa
    34561 ttgccgcagt cgattttttt agtggagata aaaatgagcg aaagaaaagt gagaaatgat
    34621 ggaaatacgg tgggcagtaa aagaagatct acctcaaatc aatcagctga ttactgatca
    34681 tccagaatca ttcgtaaaag caaaaacggc agctgaccta aatgataaga ataaactatt
    34741 gctcgttgct gtaacaaaag aaaaacggat tatcggtttt gcgcaagcgg acgtgcaaca
    34801 gtcagaagaa cgggtgggtc agcgaccatc aggaaaacta atccaacaca cattagtaac
    34861 aaaagaaaat acggaagaaa tccaaaaaaa atttgcagaa tatttgatgc tggaagctaa
    34921 aaaaagaaga ataaaatcaa tttttgccca gttttaatca aaaacagtaa tagaaggaga
    34981 aatacaatga gttgtttagg aaatgtcatc tggtttatat tcggcggact aatcggtggt
    35041 cttagctggt tagcagcggg gatactttgg tgtatcacga tcataggtat cccaatcggt
    35101 atgcaatgtt ttaagatcgc cttcctttct tttgcgcctt ttggcaaaga agtaatttat
    35161 caccagtctg gcatgtcatt gatcgttaat atcatctggc tgatcgtttc aggcctacca
    35221 attgctctcg cacatgtcgt cagcggcatc cttctatgta tcacgatcat agggatacct
    35281 tttgccaagc aatctttcaa acttgctcga ttggcgttga tgccattcgg tgcagaaatt
    35341 gtataaaaga gaataataaa ggttagataa agcatagagt caggtgggat acatgtattt
    35401 cacctgactc tatgcgtttt cctgtataag ttcttccatg tgacttttac gtcttttatt
    35461 tatatggggt tactgtttat ggaaagttga aataattttc attaaagaac tctttctata
    35521 tttttgaaag cgtagtggag cttcgtatat ctgggaagga cattttgcag ggattgaaaa
    35581 aagatattgt cctatcgaaa aattaatgaa tttagacaaa ttgccagcaa caggcttcaa
    35641 acttagttgc tatcctgtca agatcaagaa ggcaagtgcg ggttggataa gagcagtggc
    35701 aatgatcgaa gagaaaaaga aagaataagc caaaacatct gtatggaaga aattttccga
    35761 tgcagatgtt tttcattttt tctttcggat accttgacat atgaataacc attcatttat
    35821 aattagttat gaagagatat tcatatgttg aggcgaggag gtcattaaaa tgaaaagtta
    35881 cagattagaa ggtttagatt gtgcgaactg tgcaatgaaa atcgaaaaag gagttcagaa
    35941 aatcaatgga gtcaaggaag caacggtaaa cttcacttct ggaaaactaa cgattgacgc
    36001 ggaggaagat catttggcta cgattgaaca agaaacaaaa aaagtagtga aggaattaga
    36061 accagatgtc aaagtaacag aaatagataa ggaaaaagta tctgaacatg gaaatgaaaa
    36121 agagagaaat acgctgttcc ggattttatt ttcccttgca ggtatcgctt tattgctatt
    36181 atttgatttt aatgaactaa ttcgcttgat agggtattta ttgatttatc tgctgatagg
    36241 atatgatgta gtgaagaagg cagtgatgaa tatcgtcaaa ggaaaaatct ttgatgagaa
    36301 ttttcttatg tctgttgcta cgattggcgc tatgttgatc ggtgaatatc cagaagccgt
    36361 agcagtgatg ctattttatc aaatcggcga gtatttccaa ggattggcag tcagtcattc
    36421 aagaaaatcg attcgcgaat tgatggcgat ccgtccagaa acagctcacg tgcagacggc
    36481 ggaaggattg atgaccgtga accctgaaga cgtgctgatc ggtcagtttg tacttgtgaa
    36541 gcctggtgaa cgtgtaccgt tagatggaac gatcatcgaa ggagaatcat tagtcgatac
    36601 gtcagcactt acaggagaat cagtccctaa atctgtatat gttggtgaaa cagtattaag
    36661 cggatttatc aataaaaata aaccattttt agttcaagta gaaaaatctt atgaaaattc
    36721 tactatcagc aaattattag aattagtaga aaatgccagc agtaaaaaag caccagctga
    36781 aaatttcatt actaaattcg cgcgctatta cacaccagtc gttgtaggat tggccgtttt
    36841 attagctgtt ttacctccac ttgttgtttc tggagcggcg ttttctgaat ggatctatcg
    36901 agcattgaca tttttagtga tctcatgtcc atgtgcatta gtgatttccg tgccacttag
    36961 tttctttggc ggtatcggag gagcaagtaa aatcggtgta ttagtaaaag gttcaaatta
    37021 cttggagttg cttgcgcaaa ccgagacagt ggtattcgat aaaaccggca cattaacgaa
    37081 aggcgacttt tcgatccaga cgatcgatac aaaaatcgat ccaaagatat tcatgcaata
    37141 tattgcgagt gcagaacagt tttctacaca tccgattgct caatctgttt tagaaggcta
    37201 cgcaggtccg cttttaccaa cagctaatat ccaggaattt gcaggtgaag ggatcttagc
    37261 tgaagttgat ggcaaacaag tattagtagg taatcacaaa ttgatggaaa gatttgaaat
    37321 ctcttttcct tcaagtcaag aaatcggtac attgctttat ctagcaatcg atcaaagtta
    37381 cagtggttat cttgttattg cagatacctt gaaagaagat gccgtagacg cattggttca
    37441 attaaaacag gctggtgtga aaaacacagt catgttgacg ggcgactcga aaaaaattgc
    37501 tgatcatatc gggaagcaag taggcgtgga caagatatat agcgaattgc ttccagaaga
    37561 taaagtgcag cggttagagg aaatcttaca aagtaacaat aaaaagaccg catttgtcgg
    37621 agatggaatc aacgatgcac cggtgctagc aagagcagat gtaggaatcg caatgggtgg
    37681 attgggaagc gatgctgcaa ttgaagcagc agatgtagtc atcatgaatg atcaaccatc
    37741 gaagattgca gaagcaatcc atttagcaaa gaaaacattg aaaatcgtca aacaaaacat
    37801 tgtctttgct attgggataa aaattttggt actttcctta ggtgcttttg gttttgcatc
    37861 aatgggagat gcagtatttg cagatgttgg ggtgacagta ttagctgttt tgaatgccat
    37921 gcgaagcttg catgtaaaaa ataaacgttg atcaatgaag aggacgaatg aacgtcctct
    37981 tttttttata tccttttctt aatgaaaaat gtaaagaaaa tagataggat tataaaataa
    38041 ctaatgtttt taattttgca gaaaattcaa aatagcttga aattcaataa ggtcaatgaa
    38101 ataaaagaaa ataacttatt tttttgatgg aaaaaatatg aaaaaacgat gtgtattaaa
    38161 taaaataata cacacataaa ataacactgt cttgtaagtt tgttaaaaat tgaatatgat
    38221 tacatctgga taacaaattt ttatcataaa ggagagaacg aatgaacaac aaacaattac
    38281 gctggtttac tgttgcgtta attgcattta acatggtttg gggcatgggg aatgtagtta
    38341 ataactatgc tcagcaagga gtatcagttg tcacctcttg gctattgatt ttggccattt
    38401 attttattcc atacgcattg atcgttggac aattaggatc agccttcaag gatagtaaag
    38461 gaggcgtcag ttcatgggtc gaaaatacga catctaataa acgactggca tactatgccg
    38521 cttggactta ctgggtcgtc catattcctt atttggcaca aaagcctcaa gcaattctga
    38581 ttgctggtgg ttgggcagtc caaggaaatg gaaatatcgt aaatacgatg tcagtacaaa
    38641 tggtagcagt tatttcactt attatatttc ttgccttttt atatttatca acaaaaggac
    38701 tttctacttt gaaagtgatt ggcggactgg ccggaacagc gatgttcgtc atgtcgatct
    38761 tatttattct tttagctgta acggcaccgt tcatcaatcc aacgatggaa tttgccacac
    38821 cacatatgaa tcaagtgaaa acatatattc caacatttga tttcagttat ttcacaaccg
    38881 tttcgatgct agtatttgca gttggagggg cggaaaaaat atccccttat gtcaactcta
    38941 caagaaatcc tgcaaaggaa tttcctaaag ggatgatctt cttagcagca atggtaggga
    39001 tttgtgctgt attaggctca gtcgcaatgg gtatgctgtt tgctagcgat aatatcccta
    39061 aagacttgat ggcaaatggg gcatacagtg cttttcaaat tttaggtaat tactatggta
    39121 tcggtaactc attgatgatc atttacgcat tgacaaacat gattggacaa atctccgcat
    39181 tagccttttc aattgatgca ccactaaaaa tcttgttagc agatgcggat ccagaatttg
    39241 taccaaactg gctacgtaaa cgtaatcgta aaggtacatt ggtgaatggt tatcttctga
    39301 caggtatact agtaggaatc attattttgt tgccgatctt tggtatcaaa gatatgaatg
    39361 aattagtaaa atggttgacg aacttgaact cagttgtcat gccaatgcgt tacctatggg
    39421 tgttcttggc atatatgatg ttgaataaag cttataagaa attcaattct gaatataaat
    39481 ttgttaaaaa tccaaaaatc ggttttatct ttggtgcttg gtgctttgcc ttcactgcgt
    39541 ttgcatgtat cctaggaatg gtgccaaaag tagattatac tgctgatcct aaagcatggt
    39601 ggttccaatt attcacgaat atcatcacac caattgtctt gatcttatta ggtatgatct
    39661 tgccagcaat tgctcgtcga gacaaaaaca aagaaattac tgaaccagaa acagtggttc
    39721 agccttaaaa tagaaatact tgttacaaga ggttgtgaca gaagctactt ctggaacacc
    39781 gtgaatcaga ggttgtgaaa aagctgtcct gcatcaagta ataagaacag ccaaacaaaa
    39841 atagctcctc atattttgcc gttttttgag ctaatgctga aggtcagctg attgaacacc
    39901 atttattcga aacaagggac tttgacacga cttttgtcac agtcccttgt ttttttgcgg
    39961 cgttataagt ggtatgatcg aaccaaattc caaagagaag tgagggagaa gaatgaagat
    40021 catcgtgatt ggacaaagtg ggtcgggaaa atcgtccctc gcaaggaaga tcaaagaaat
    40081 caccggcttt ccgcattcag gcaaaaaagt ggtttttgca agaacagcaa tcgtttatag
    40141 tatctaatcc gtcatggatc gttgaaggaa attatacttc tacgttagag gaaaggatta
    40201 aagaagcaga taagatcatt tggcttaaag tgccgcgtta tctcgccatc taccgagtag
    40261 tttggcgttc tctaaaaaga aagataaaca aaaaatctcg gccagatatg cctgaatcat
    40321 tttcggagaa actaaacagg aaatacttag aatttttatc ttttatctgg cattttgaag
    40381 gaaacaatga accaaaaata cagcagctga tccaagtagc taatgcaaga aataaactga
    40441 tcatccttaa aacaagacga gagaaacaag aatttttaac taaattgaaa atagagagca
    40501 aaaataattg acagtttttg tttacaagcg taatctgtat tcataagcta atgattacat
    40561 ttgtaaacga aaggtgtgaa ataaatggaa aaagtcaaaa cgccagtaaa gatcagtgat
    40621 tcagagtggg agatcatgcg tgttatttgg acacttggac agacgacagc ccaagaaatc
    40681 acgcagatct tagctgattc gatggattgg aaaccagcaa cgatcaaaac tttgctggga
    40741 cgtttggtaa aaaaagaagt gatctggaca gaacaaaaag gaaaaaaatt catttatcat
    40801 ccagctgtct cggagatgga aacagttcgc agtgcgacgg aaaatctttt ttcccatatc
    40861 tgtgcaaaaa ggattggaga gacgattgcg gatctagtag aagaagctac tttgactcaa
    40921 gaagatatca atgagatttt gaaacaactg gaacaaaagc aaccagtaga tacgatcgaa
    40981 tgtaactgta tcccaggtca atgtgaatgt aaacaacatc aataggagga agaaaaaatg
    41041 aaacaacaat tttcaatcga aggtatgagc tgcaatcatt gtgcagcaag agtagaagaa
    41101 acagtaagcg cacttgacgg cgtgcaaaaa gtgaaagtaa atttgaaaaa agcaaacggt
    41161 acggtcaagt ttgatgaaac aaaagttcaa tccgaaaaga tttgtcaagc aatcaatgga
    41221 ttgggttata aagcagaggt gatttgatgg caacagcaga aaccaaaatg gatacgttcg
    41281 tcattacagg tatgacttgt gcaaattgtt ctgctaggat cgaaaaagag ctgaacggac
    41341 aacctggtgt ggtcaatgcc acagtcaact tggccactga aaaagcaagt gtcaaatatg
    41401 aagggacgac cactgaaaaa ttaatccaaa gcgtagaaaa catcggttat ggtgcaattt
    41461 tgtacgatga agcccacaaa caaaaaattg cagaagaaaa gcaagcgtat ttgaaaaaaa
    41521 tgctattcga tcttatattg agtacggttt tgactttgcc gttgatgttg tcaatgattg
    41581 ctatgatgtt aggaagccat gcggcgattg ttcacttttt tcattttcca atcgtccagt
    41641 tagtgctgtc tgctcctgtc caattttatg tcggtgctcg tttttataaa ggtgcgtacc
    41701 atgcaatcaa gacgaaagca ccaaatatgg atgtattggt agcaattgga acatcggctg
    41761 cctttgcatt gagcatttac aacggatttt tccgtggaca cccccaagat ctttattttg
    41821 aaagcagcag tatgatcatc acgctgattt tgctcggcaa atatttggaa catacagcaa
    41881 aaacgaaaac aggtaatgca atcaaacaat tgatgtctct tcaaacaaaa accgcccaag
    41941 tgataagaaa cgggaaagaa gaaacgttag cgattgaaga agtagtcgtt ggtgatcaac
    42001 tagtcatccg tcctggtgag cagattccag cagatggtcg aattatttca ggaagcagtg
    42061 cgatagatga aagtatgctt actggtgaaa atcttcctgt agaaaagaat ccggatgaca
    42121 cgctttttgg cgggacaatc aatacgaatg gtctgctaca catggaagtc acacaagtcg
    42181 gcaagcagac agtattagcg caaatcattc aaatggtgga agatgctcaa gggagcaaag
    42241 ccccaatcca aaaaatcgca gatcggatct cagggatttt tgttccgatc gtattagtca
    42301 tcgcgtttat cacgctcata gctacaggtt tgatcactgg tgattggcaa ctcgcattga
    42361 tccatagtgt ctctgtatta gtcattgcgt gtccatgtgc attaggttta gcgaccccaa
    42421 cagctattat ggtaggaacg ggtgttggtg cacgaaatgg aattttaatt aaaggcggag
    42481 aagcattaga agcagctgct cacttagaca gcattgtttt ggataaaact ggaacgatta
    42541 cagaaggaaa gcccaaagtt acagatctag tcggttcaaa agaagtccta tctatttttt
    42601 atactttaga acaagcttct gaacatccac taggtaaagc aatcgtggaa tacggaaaac
    42661 tgcaagaagc agcaacatac gatatgattg attttacagc ccacccaggt gctgggatca
    42721 gcggtacgat taatggagta cgctattttg cgggtacacg taaacgatta attgaattga
    42781 acctatcatt tgatgaatac caagaacacg cgttagaatt agaacagcag ggaaaaacag
    42841 tcatgttttt agctgatgaa aagcaagtga tcgggtggat tgccgtggct gatcaaatca
    42901 aactagaagc caaacaagca atcaagcagc tccagaataa aggattagat gtttttatgc
    42961 tgacaggaga caacaaactg gcagccgaaa cgattggtaa acaagttggt attgatccaa
    43021 agcatatctt tgctgaagta cttccagagg ataaagcagc ctacgtagaa aaacttcaga
    43081 aagatggcaa aaaagtcggt atggcaggcg atggaatcaa tgatgcaccg gccttagcat
    43141 tagctgatgt cggtatggca atgggaagtg gaacggacat tgcgatggaa acagccgatg
    43201 tgacgctgat gaatagcagt ttggcatcca ttgcacaaac aatcgagttg tctaggttga
    43261 cattgagaaa aatcaaacaa aatcttttct gggcttttgt ctataatacg attggtattc
    43321 cttttgccgc actaggcttt ttgaatccaa tcattgcagg aggagcgatg gcgtttagtt
    43381 ccgtcagtgt attgttgaac tccctgagct taaatcgaca catgaaaaag taagagaagg
    43441 gatggagtaa aaatgaatgg gaacgatatg gagaaaaaac atgagcataa aaaagaagta
    43501 gtaaacaaag aaagtacaga atctcatgaa aaacagatgg agatgaaaca tgaccatagt
    43561 cagatggatc attccatgca catgggacat aaccatggag atatagcaaa cagcaaacaa
    43621 atggaccatt cgatgcacat ggatcacgaa cacggcggca tggatcattc catgcacatg
    43681 gggaatttca aacaaaaatt ttggctatcg cttatcctag ctatcccaat cattcttttt
    43741 tcaccaatga tgggaatgga atttccattt caagtaacgt ttcctggttc tgattggctc
    43801 gtattgatct tagcaactat actatttatc tatggcggtc agccattttt aagtggagct
    43861 aagatggaat tgaaacaaaa aagtcctgct atgatgacac tgatcgcgat ggggattaca
    43921 gttgcatata tttatagtgt ctattcgttt atcgcaaatc tgctcaatcc acatacacac
    43981 gtcatggatt tcttctggga attggctact ttgatcgtta ttatgctact aggtcactgg
    44041 attgaaatga atgctgtgtc gaatgccagc aatgctttac aaaaactagc agaattactg
    44101 ccagaatcag tgaaacgctt gacgaaagat ggaaaagaag agacagtttc attgaaagaa
    44161 gtaaacgaag gtgatcgttt gatcgtccgg tctggtgata aaatgccaac agatggtgta
    44221 atcttgaaag gtgaaacaat tgttgacgaa tcagctgtga ctggcgaatc aagaggaatc
    44281 aaaaaacaag ccaatgacaa agtgattggc ggttctatca atggggatgg aacgatcgaa
    44341 atcgaagtaa ctggaactgg tgaaaatggt tatctagcga aggttatgga aatggtgcga
    44401 aaagcacaag gagaaaaatc caagctagag tcattatctg acaaagtggc aaaatggctg
    44461 ttttatgtcg cattaattgt gggtatcctg gcattcatcg cctggttgtt cttgacagat
    44521 cttcctaatg cattagaacg tatggtaaca gtctttatca tcgcctgtcc tcatgctcta
    44581 ggtttagcta tcccattagt tgttgctcgc tccacatcaa tagcagctaa aaacggatta
    44641 cttttgaaaa accgcaatgc actggagcaa gccaatgatc tagatgtgat catgctggac
    44701 aaaacaggaa cactaacaga aggaaaattt actgtaacgg gtgtcgaagt acttgatgat
    44761 gcgttcaata aaaatgaaat ccttcaatat ctaggagcct tggaagcgaa tgccaatcat
    44821 ccattggctg ttggcattat gaattatttg aaagaacatg aaatcaagcc ttatcaagct
    44881 gaaaatctaa aaaatctttc aggagtcggg ctagaggcaa cagtcaaaaa acaacaagtg
    44941 aaaatagtta atgaaaaaga agttgagcgt ctcggattaa acgtagaaca agcattattg
    45001 aaaccttacc aagaacaagg aaataccatc agcttcctga ttttagaaaa tcatctagct
    45061 gcaatcgttg ctttaggtga cgtagtaaaa acagaagcaa aagaatttat ccgaacattg
    45121 aaagaaagaa aaatcactcc tgtcatgctt actggtgaca ataaaaacgc tgcccaagca
    45181 gtagcagatt atttagggat cgaagaatat tatggcggtt tattaccaga tgataaagaa
    45241 gctgttgtcc agaaatacct tgaccaaggg aaaaaagtaa tcatggtggg tgatgggatc
    45301 aatgatgcgc caagtttagc ccgtgcttca atcgggatgg caatcggtgc agggacagat
    45361 atcgcaatcg attctgcgga tgtcgtattg acaaacagcg atccaaaaga tattttgcat
    45421 tttcttgatc tagccaagca aacgcgaaag aaaatgatcc agaacctctg gtggggggca
    45481 ggttacaata ttcttgcaat tccgctagca gccggaattc ttgcgccaat tggtatcata
    45541 ttaagtccag cagttggtgc tgtcttgatg tcgttaagta cggtagttgt agctctaaat
    45601 gctttgacat tgaaaatcaa ataataatga aaaaaggttg tgacaaaaaa cgtgtcacaa
    45661 cctttttttc gagtaatcga tactcaatca gctggttctc ggcattccag aagtagattc
    45721 tccagaaatt ttatcttatt ttttgaagcg gctccctttt gtcagaattt ttttgtatac
    45781 cgtttttctt attatacgcg ttatttctaa ataggttttt ttatcgaatt ttaccggatc
    45841 tgcttgtcgt ccatatattt ctgcttcata ttgagtagtt aatcgaatga aacgcagatc
    45901 tagcttgaat tcttgttcta ttcgcaggct atattcctgc aaagattctg cgggtttgcg
    45961 cggtaccaat gtttccaaag ggttaagaag tttttgatat gcaatcgtat tagtagaagc
    46021 aaaaaaatga agatagataa gataacttgt ccagcgcaga gattttctga ataacaatag
    46081 aaagaacaac aagacggata aacacactcc aaggctgaat aagacgattt tataagctgg
    46141 tgtgagtgtt gtttcttctg atggaatgac ctcagatctc tcactggaaa tagtttctgc
    46201 catattttcg ctttcatttg gttgttcgat agcaggctgg acggtttcgg ttgtttcagc
    46261 aactggttgt gaacccattg gattggcaaa tgaaggggtt ggttcaaatg gaagccagcc
    46321 aaatccagga aagtatacct ctggccaaga atgagcatga ctattgagaa tgctgtattc
    46381 ctcattccct tgattatctg tgcctgttct gagcccattt gtaaaacctt ttgtccagcg
    46441 agctgggata ccaagtgttc gaagaaggac gaccatagaa gttgaaaagt tgtcacaata
    46501 gccgactttt gaatcaaaga ggaaataatc cacataatcg tgttctttcg gagtatgccc
    46561 ggtatccgtt ttggaatagc ggaaatttcc gcttgttttt aaatactgtt agacagcttc
    46621 gactttacga attaaagttg cttcattttt ggtcaattcg accgccaagt cctcaatacg
    46681 tttaggcaaa ctttttggca attgaagatt tgtctgctga ttttctaaat catcagcttt
    46741 taactgactg ctttttaatt cttctctcgt aaaaactaac ctttctgttt gtaaagttgc
    46801 agaacgtgtc gattcattcg ggacaggaat gaatcgctgg ctttcaggca aatagtaaag
    46861 cgtttgtcca ctagctaatg aaaaatcagt caaggtagta tttccataag gataaggtaa
    46921 gaaagcttgt ttttttaggg tcaatgtaat gttttctttg tcttctataa cggtttggta
    46981 gctcgtgatg tcaacaggga attcttggat tggttggatg ggtgcgtcct gatcttctat
    47041 ccatccagaa ccggtgtaat gatttttatt ttcgatcttc caatagccat ttcctttttg
    47101 gttcgctgta aaaacaactt cgccattatc atataaaggt ccaccaagct gttcatcatt
    47161 ctcactgaag cctgttcttg cacttccggt taattgatac tcatggagtg tgtcataaag
    47221 cccttcatca ttaagatatt ctcggatcgg ttcactcgtt tcctcgagag attggtgtac
    47281 tttcggaaga tataaaggca agatagcgct aaaagttaag aaacaaataa gcagaactgt
    47341 agtcaatgac tggaatcgag tgtttcccga caacaaccgg atggagaaaa attgccttgc
    47401 tgccagatac acgaacaaaa cagttactac cgcaatcatt tcgtacagta aatctttttt
    47461 ccgaaaaacg gtaagcatca tgaagtaagc catcaaagaa agaaagggtg cgtaccaata
    47521 gtcgtaatcc acggtcaatg taataaataa atagatcagc aacattatga gaaaaaaagc
    47581 tgtcttttct ggcaaataat aaagtttacc ttgggataga tggaagaatt cctctgtaac
    47641 tgacgaaaaa aactgtaaga tccataatat ggaaaatgtc ttcgaaggaa aatataaaaa
    47701 caaacaacct atcattactg gcaaagaaag cagcaaacgt acccattttt taggaataca
    47761 gcagacaata aggcatagga caccaatagt taggataaga aggtagctgt tttgcaattg
    47821 attagctact acaaatatcg gagcacctac acttagtatc acaaaggagt aaacgccacg
    47881 cagccatttt tcccgtttaa tcgtcaatcc attcacctcc tggcaatgaa catatcttgt
    47941 ctttttcttg gaccatgagt tgtttttcta cgaaataaac aagataagcc gttcgatctt
    48001 ttgacaatgt ttcaatagct tctgagactt caggagaatt ctcaggaaca aagaggacga
    48061 tttgtttttt tgcatatttt ttcaagtgtg cgaaaaaagc tttctcatcg ccagcttcca
    48121 aagaagcaaa ataggtatga ccggggtctt tgccatgaaa ggcgcggttg cctaatatca
    48181 gaagttccgg ctgcttttct tttctcaaat gccataaaga aaaatacaag tctagcagag
    48241 gttcaaattt tggactgggc gaaccccaaa agcaaaaaag aggagaacat tcttcttctt
    48301 gataatcgta ttcacggtat aaccactctt gagtatgagc agacaatttc caatcgattc
    48361 ggttgaaaga atcacctgga cgataagcgc gatgttcccg aaaatcaaga cctctttggt
    48421 acgcgttcag ctgctgtttt ttttccagaa ctctctgtaa tttttctgct tgaatcttac
    48481 aaaaagcagg cagaacagtc acaggaaaag agatctctct ttttgcactt tttctgaaaa
    48541 gtcctagact atcataggct gtaaaaatga cagttaatgt ttcatggcat cctctttctt
    48601 ttggctgcca aagcaattgg acttcttgcg gtttatttgt aagaatcaaa atctcttgtt
    48661 tttttctgca aagattgctg ggaagccgat ttgtaaacga gggagaggta aagaaaaagt
    48721 tctctttttt gctatggaaa aaataacctg catacttttt ttgcgataaa cgagtggctg
    48781 caatgtacaa gtaaccgaaa gtttctttag aaagctgctt aatgaaatca agctccatga
    48841 tacataaaga gtaaaaaagg ccaacaagaa ccagcctaaa gaattgttga atacaagagc
    48901 aaaaagcaca atgatgaaat ataccagaaa taacacaaaa ttaatgaaat aatctttgat
    48961 tttttccatt gtctacctca atctacctca caggaatagg aatttgtgca acaagagtat
    49021 gaatgatttg tttcttttcg tcttccttca atgaacgatc gtaaaaaatc aggcgatggg
    49081 aaaacacgta aggaactaaa tcctgcaaat ctttgggcgt gacgtaattt ctcccatgga
    49141 ttaaagcata agcttttgct gcctgaataa aggaaaggct tcctcgtgga ctgatgccaa
    49201 gctggatggc agcatgactt cttgttgctg acactaactg caaggcataa gatgccactt
    49261 cgggactgac aaagacattc gccacatttg tttttatttc ttctatttca taactgttca
    49321 atacttcatt taagttatcc aacacttttt cgaatttatc caaaagtagc aaaagttcgt
    49381 catcaaaaga aggataaccg atttgtagtc ggaataaaaa acgatcgagc tgtgcttccg
    49441 gcaaaggata tgttccttcg tactcgattg gattttgcgt agctaagaca aaaaaatgat
    49501 tgtctagagg gtatgtattg ttgtcgatcg ttgcatgatt ctcggccatt gcttctaaaa
    49561 gtgctgactg agtacgagga gtcgtacgat tgatctcatc tgccaacaag atcgtggtaa
    49621 agatcggtcc cggacgaaat tcaaactctt ttgattgtga attgtatacg gaaaaaccaa
    49681 gaatatcact aggcagcaga tcaggagtac attggactct gctgaaggtt ccctgtacag
    49741 cttttgctag tgctttgacc agtaacgttt tacctacacc gggaatatct tcgaataaga
    49801 catgaccacc tgctaatagg gccacgatca tcaattggat agttgaacgt ttgccgatga
    49861 ccgctttttc taattcttat atcaactgat cgattttttg tttggattct tctatttttt
    49921 cttccatttt cacatcacct tctcataaaa tcgctattta tttcattgta atggaaggga
    49981 atacatccta caagcaaagt gatcttatta tgttttttta aagtacattc gttttgaaat
    50041 gagaatacga ttaaattgag taaaataaaa aataatgagg aagatttgcg tatttaaata
    50101 aatagaaagg gagtttttta tctttttagg agtgaactca ttttgatcaa acaatatgtt
    50161 tagaaatcag gtgagaaatg atcgatgaga tggcaaaaac tattatcaaa aaatgcacag
    50221 aatttatttt cactaatcaa tctaatgaaa gatttgatct ggcgaaaagc tgatttagct
    50281 gaagaactga aaatcgatgt taaaacagtg gatcggcatc tgaaacgttt ggcggaaagc
    50341 gactgtccca ttcagctgat tcttcataag aaaaccgttc agttagttta tgatcaagga
    50401 tatagcgaac cttatctctt gtttgttttt ctgatccaat cacccccgtt ttgtttactg
    50461 aaaaatctgc tattaaatga accttacgag cagaagtacg atcgttctac gcaagagcga
    50521 ttgagaaagt ggtttggcga gtaccacctt tctttttctt ataaaaaagc acagatcttt
    50581 ggttcagaaa gaaaagtaag atatctgctg ttttactttt tgaaagattt tccgcatttt
    50641 tttgcagatg atggagagca gtccttttct gagatgttca tccaattatt gaagcaaaga
    50701 aaggatccgg cagaaatcga gattttagga gacagtcgaa cactattctt tgaattgttt
    50761 cctgaattgc tatttagaga ggagcagatt ttgccaataa aagaaaaaaa ttatctagca
    50821 attttgcgct tgagctgtaa ccagattact gaaaagcggt ggaaacggat agaagagaca
    50881 caagactatc ggaaattgac gattgtgact gaaaagcttg attcgctgtt ttggctgaat
    50941 agcgaatttg agagcgaaag caaatcaaag ctgataaaag tactttacca agaatggctt
    51001 cgttacgtaa ttggtatcca tgaccggctg atagaagaag ttcgttatta tcaggaaaca
    51061 ttagaaaaat ttcccaattc caaagataaa ctatatcaat ttcggctagc gatccaacaa
    51121 gcacttgcac accccgcagt agagtggggg atgcttttac tgaaaacact ccaggaacga
    51181 gggtatttag atgtccaccc tcctgaagtg aaaatcgtct ttttttttcg ctatgaacac
    51241 caagaagcaa gaagacttgc tggggtactg aacaaaacgc taagacatcg aaaacggatc
    51301 tctatacatg tatgtactcg aaataagccg cctcggtatg cagatctagt gatcaccgat
    51361 catttttttc cactagacca taacgaagat caaaaaacgt atctgtacca tccttcattt
    51421 ggtatcgaaa gacttcttac cgatatcaat tactggttag gcaaaaaccg ataaaacctt
    51481 tggaaaaaag atcaaaacaa gtcagtctgt gctataataa aaagcgatta gtaaaggagg
    51541 aaatccattg gaattaaaga aattagaagt tcccacatct tcgatcacag aagtgaaacg
    51601 atcgccgatg gatgtatttg ctcaagcgcg agacgcggga actggcgtat atatatttaa
    51661 tcgtgaaaaa gtagctggcg tgatgctgac ccaagaacaa tacaaaacgc tcttgcaaga
    51721 actagatgtc cttcgtcaaa cagtgaaagt ggagaggaaa gaaccaaaag aaataaacga
    51781 agaacctatt aacaaaacag cttccgtcgt atccaatgct gaagggatgg aagagctggc
    51841 ccaaacatta cagcactcgc tcattactgg tgtgacgatt acagcaaaaa atctagatga
    51901 acgaatggta gcactaggtt ttattacgaa aaagaccgga tttggcggag tcgtggatat
    51961 gcttagcgag ttgatggaaa ctgggaaaat caactaccag ttaagaagaa aaccgcaaaa
    52021 tcggacaatc atagctgaaa tcataggaga gcaaaacagt caatctcaat tgatggataa
    52081 aatcatcatc aagaaaattt ttctacatga gctataagaa aaccatgttc gcacttctag
    52141 gcaagccagg ctttgaagac cttgccaaag aattgaacga acgcctttaa gataagggtt
    52201 tttcgctaga tttaaaaaat cagtgataga aacatgttcg cttataaata aaattagtga
    52261 tagttttagt gatagtgagc ttaaaaaagc actcaatttg agtgcttttt tatttgctct
    52321 tctatatagt tttctagttg attcattgat ctttttttca cttcgggaga aatatgggca
    52381 tagacttgtg tagtggaaac atctttatga cctaaaaaat ctttgatatc ttctaaaggt
    52441 attcctgctt gtctcgttct agctgaaaaa gcaaaacata atgttggtgt tttcctttca
    52501 gcatatctat cagcaagatg tagagtagga caacctcgtg agccaaaagt cctgtgcaaa
    52561 tcgagttaca acacacacat gataaagaaa cttttgaaaa gaactataaa gtatacgttg
    52621 aattggcaag agattcagca atgaaatatg gtattccatt aacattagac actccttata
    52681 accaaccagg aatcaaatcg catttatggg taacacaaaa tatttggggc gatcatacag
    52741 atccttacgg ttatctttct gaaatgggtg taagtaaaga aaaactagcc tatgatttgg
    52801 ctcatggttt tacggatgat aatccaacta cttcggagga taaaccagta attgatccaa
    52861 ctcgagcagg tgctgcaaat tctacgctga cagatggaac aaattacgcc cacattgatc
    52921 agttcggaga aatcgaaaac gcaaacttgc atgtagctgg atggcacatt gctaattata
    52981 aatacgagta tattttcatt atggactaca atactggaaa agaactagct agagtaagag
    53041 ctgatgggat ttatagacca gacgtaaatc aagcttataa tactttagga aatgttggct
    53101 atcatgtatc tttcaatatg cgtgatttcc ctaataagaa agtatacgtc atgatgcgtg
    53161 cgacaaacga tccagaagga aatactaagg gtggagcaca agattttcat gacaagcgtt
    53221 ggtatttaaa tattccacaa cgataaaaaa tccccccctc ttt
//
LOCUS       DAZAOD010000011        51892 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000011 DAZAOD010000000
VERSION     DAZAOD010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.011"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1134
                     /locus_tag="ACHDPO_000699"
     CDS             <1..1134
                     /locus_tag="ACHDPO_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFN3368351.1"
                     /translation="IKKLFLETEVDKIDIQNKKISCVKKDGTRFSQEYDKVILATGSK
                     QIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYIGVEIAEAIRKRG
                     KEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYLGRKKIEKIVTTS
                     GTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKDIYAIGDCATTFF
                     TSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFNYNFYAAGLNLKT
                     ARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQLCSQEDLSGLLSM
                     FSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            1246..2697
                     /locus_tag="ACHDPO_000700"
     CDS             1246..2697
                     /locus_tag="ACHDPO_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFN3368352.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            3046..3678
                     /locus_tag="ACHDPO_000701"
     CDS             3046..3678
                     /locus_tag="ACHDPO_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFN3368353.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            4266..5705
                     /locus_tag="ACHDPO_000702"
     CDS             4266..5705
                     /locus_tag="ACHDPO_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3368354.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            6000..6218
                     /locus_tag="ACHDPO_000703"
                     /pseudo
     CDS             6000..6218
                     /locus_tag="ACHDPO_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            6467..6682
                     /locus_tag="ACHDPO_000704"
     CDS             6467..6682
                     /locus_tag="ACHDPO_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368355.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(6899..7155)
                     /locus_tag="ACHDPO_000705"
                     /pseudo
     CDS             complement(6899..7155)
                     /locus_tag="ACHDPO_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7342..8253)
                     /locus_tag="ACHDPO_000706"
     CDS             complement(7342..8253)
                     /locus_tag="ACHDPO_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFN3368356.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(8272..9276)
                     /locus_tag="ACHDPO_000707"
     CDS             complement(8272..9276)
                     /locus_tag="ACHDPO_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFN3368357.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(9273..11396)
                     /locus_tag="ACHDPO_000708"
     CDS             complement(9273..11396)
                     /locus_tag="ACHDPO_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFN3368358.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(11401..13848)
                     /locus_tag="ACHDPO_000709"
     CDS             complement(11401..13848)
                     /locus_tag="ACHDPO_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3368359.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(13835..14224)
                     /locus_tag="ACHDPO_000710"
     CDS             complement(13835..14224)
                     /locus_tag="ACHDPO_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFN3368360.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(14284..14787)
                     /locus_tag="ACHDPO_000711"
     CDS             complement(14284..14787)
                     /locus_tag="ACHDPO_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFN3368361.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(14800..15024)
                     /locus_tag="ACHDPO_000712"
     CDS             complement(14800..15024)
                     /locus_tag="ACHDPO_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368362.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(15128..17038)
                     /gene="ltrA"
                     /locus_tag="ACHDPO_000713"
     CDS             complement(15128..17038)
                     /gene="ltrA"
                     /locus_tag="ACHDPO_000713"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFN3368363.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(17784..17921)
                     /locus_tag="ACHDPO_000714"
     CDS             complement(17784..17921)
                     /locus_tag="ACHDPO_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFN3368364.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(17918..19102)
                     /gene="mobT"
                     /locus_tag="ACHDPO_000715"
     CDS             complement(17918..19102)
                     /gene="mobT"
                     /locus_tag="ACHDPO_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFN3368365.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(19361..19651)
                     /locus_tag="ACHDPO_000716"
     CDS             complement(19361..19651)
                     /locus_tag="ACHDPO_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368366.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(19641..20783)
                     /gene="dcm"
                     /locus_tag="ACHDPO_000717"
                     /pseudo
     CDS             complement(19641..20783)
                     /gene="dcm"
                     /locus_tag="ACHDPO_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(20859..21023)
                     /locus_tag="ACHDPO_000718"
     CDS             complement(20859..21023)
                     /locus_tag="ACHDPO_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368367.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(21016..21690)
                     /locus_tag="ACHDPO_000719"
     CDS             complement(21016..21690)
                     /locus_tag="ACHDPO_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFN3368368.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(21768..23108)
                     /locus_tag="ACHDPO_000720"
     CDS             complement(21768..23108)
                     /locus_tag="ACHDPO_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFN3368369.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(23191..23526)
                     /locus_tag="ACHDPO_000721"
     CDS             complement(23191..23526)
                     /locus_tag="ACHDPO_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFN3368370.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(23536..23910)
                     /locus_tag="ACHDPO_000722"
     CDS             complement(23536..23910)
                     /locus_tag="ACHDPO_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFN3368371.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(23923..24237)
                     /locus_tag="ACHDPO_000723"
     CDS             complement(23923..24237)
                     /locus_tag="ACHDPO_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFN3368372.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(24350..27577)
                     /gene="fss3"
                     /locus_tag="ACHDPO_000724"
     CDS             complement(24350..27577)
                     /gene="fss3"
                     /locus_tag="ACHDPO_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFN3368373.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            28434..28688
                     /locus_tag="ACHDPO_000725"
     CDS             28434..28688
                     /locus_tag="ACHDPO_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368374.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            28852..29769
                     /locus_tag="ACHDPO_000726"
     CDS             28852..29769
                     /locus_tag="ACHDPO_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFN3368375.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            29762..30544
                     /locus_tag="ACHDPO_000727"
     CDS             29762..30544
                     /locus_tag="ACHDPO_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFN3368376.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            30545..31225
                     /locus_tag="ACHDPO_000728"
     CDS             30545..31225
                     /locus_tag="ACHDPO_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFN3368377.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            31218..32114
                     /locus_tag="ACHDPO_000729"
     CDS             31218..32114
                     /locus_tag="ACHDPO_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFN3368378.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            32326..34248
                     /locus_tag="ACHDPO_000730"
     CDS             32326..34248
                     /locus_tag="ACHDPO_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFN3368379.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            34249..34695
                     /locus_tag="ACHDPO_000731"
     CDS             34249..34695
                     /locus_tag="ACHDPO_000731"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFN3368380.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            34711..35025
                     /locus_tag="ACHDPO_000732"
     CDS             34711..35025
                     /locus_tag="ACHDPO_000732"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFN3368381.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            35051..36100
                     /locus_tag="ACHDPO_000733"
     CDS             35051..36100
                     /locus_tag="ACHDPO_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFN3368382.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            36112..38715
                     /locus_tag="ACHDPO_000734"
     CDS             36112..38715
                     /locus_tag="ACHDPO_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFN3368383.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            38832..40481
                     /locus_tag="ACHDPO_000735"
     CDS             38832..40481
                     /locus_tag="ACHDPO_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFN3368384.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            40797..41732
                     /locus_tag="ACHDPO_000736"
     CDS             40797..41732
                     /locus_tag="ACHDPO_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368385.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            41725..42495
                     /locus_tag="ACHDPO_000737"
     CDS             41725..42495
                     /locus_tag="ACHDPO_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368386.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            42910..43893
                     /locus_tag="ACHDPO_000738"
     CDS             42910..43893
                     /locus_tag="ACHDPO_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFN3368387.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            44214..45251
                     /locus_tag="ACHDPO_000739"
     CDS             44214..45251
                     /locus_tag="ACHDPO_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFN3368388.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(45340..45663)
                     /locus_tag="ACHDPO_000740"
     CDS             complement(45340..45663)
                     /locus_tag="ACHDPO_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFN3368389.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(45650..46357)
                     /locus_tag="ACHDPO_000741"
     CDS             complement(45650..46357)
                     /locus_tag="ACHDPO_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFN3368390.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            complement(46656..48080)
                     /locus_tag="ACHDPO_000742"
     CDS             complement(46656..48080)
                     /locus_tag="ACHDPO_000742"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFN3368391.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            48255..48968
                     /locus_tag="ACHDPO_000743"
     CDS             48255..48968
                     /locus_tag="ACHDPO_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3368392.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            49117..50448
                     /locus_tag="ACHDPO_000744"
     CDS             49117..50448
                     /locus_tag="ACHDPO_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFN3368393.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            50716..50868
                     /locus_tag="ACHDPO_000745"
                     /pseudo
     CDS             50716..50868
                     /locus_tag="ACHDPO_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(51013..51888)
                     /locus_tag="ACHDPO_000746"
     CDS             complement(51013..51888)
                     /locus_tag="ACHDPO_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFN3368394.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
BASE COUNT        16116 a         9656 c         9730 g        16390 t
ORIGIN      
        1 ataaaaaagt tatttctaga gacagaagtt gacaaaattg atattcaaaa taaaaagatt
       61 agttgtgtaa aaaaagatgg tacaagattc tctcaagaat atgacaaagt tatattagct
      121 acaggttcaa agcaaattat gctagatata ccggggaata atttagctaa tattttttcg
      181 ataaagaatt ttccaaatgc aaaagagatt tttaaagctt tggatgatag tactattaaa
      241 aaagtaggaa ttattggagc aggatatatt ggagttgaaa ttgctgaagc cataagaaaa
      301 agagggaaag aagtatatct tttcgatgtt gcagatagag tgttgtcgac ttattacgac
      361 cgtagttttt cagataaagt tgaagaaata ctatcaaaaa atggaataca tctttgtcta
      421 tcagaaagtc ctaaaaaata tttaggaaga aaaaagattg aaaaaatagt cactacaagt
      481 ggtacccaat actctatgga tatggtcgta caagctatag gatttctatc taatagtcca
      541 attggggaaa aggaactctt gagagatgtt agtggagcat atctaactaa tgaataccag
      601 caaacaaata taaaagatat atatgctatt ggggattgtg ctacaacttt ttttacgtcc
      661 attaatagaa gtagtgttga tttttctatt tctaatgctc taagaacagc ttatattgca
      721 actcaacata ttaacaatca agattttaca ccttctggtt cccaatttac aaatggcttt
      781 tctatattta attacaattt ttacgcagca ggtttgaatt taaaaacagc acgattatta
      841 agtgagtcta tagattatat agaaatagaa gatttcatta gacctgcttt tttgagaaaa
      901 aatagtcgtg taaaattaag aattagcttt gaaaaaaata caaagagaat agtaggtgta
      961 caactttgta gtcaagaaga tttatctgga ctattatcaa tgttttctct tgctatagaa
     1021 gaacaaatta cattagacaa attgaaaatg ttagattatt tatttcatcc tagttttagc
     1081 caaccctata attttatttt aaaggcagta acaggattaa acattgaaac ataatcgtta
     1141 ctaaatgaaa tcaagaaata tactgtatta ctcaattcat tgaaaatatt tatcataatt
     1201 tttaatagaa aacactatta aagagaaaaa agagaggtaa atcaaatgaa aaaatcttta
     1261 aaacttgcat cagcagttat attaatgtcc caactcctta tagcaacacc tttccatgtg
     1321 ttggcaagcg aaaattcaac atacaaaatt gcaaaagaaa gaaccgagac gactgaaatg
     1381 agtaattccg atgtaacagc agagagtagt gaacttttga caacttcatc aagtgaaagt
     1441 agtacgactt caaatgccga gtcttcaaca acttcatcaa gtgaaagtag tacgacttca
     1501 aatgccgagt cttcaacaac ttcatcaagt gaaagtagta cgacttcaaa tgccgagtct
     1561 tcaacaactt cgtcaagtga aagtagtacg atttcaagta ccgaatcttc aacaacttca
     1621 agtagtacaa gtgaaataac ttcttcgaaa gtgacaaaac caaaccatat agaatcttca
     1681 aaaaaggaag cgccaaaaac ggaaggacaa acaaaaactt tttcgacacc acagcaaata
     1741 gaatcaacag aatctttcca atcacaacca atactatctg gtaatgaaga aattcatttt
     1801 gacaaaaatg aatctgtaga aaattttatt atgaaaattg gtgagtctgc gagaaaaatt
     1861 ggtcagaaat atgatttata tgcttctgtt atgattgcac aagcgatctt agaatctgcc
     1921 agtggtcaaa gccagttagc tcaggcaccg aattacaatt tatttgggat aaaaggaact
     1981 tataatggaa actttgtcat tatggtaaca aacgaagatt tgggtaatgg aacgctttat
     2041 acgacccaat caaaatttag agtgtatgaa aactatgagg aaagctttga agattatgcc
     2101 aaattattaa ctaagggaat tagtggaaat aaagattttt atgcaggagc attaaaagct
     2161 aatagtaaaa catatcgaga agcaactaaa ttccttacag gacggtatgc aacagataca
     2221 caatactatt tgaagctaaa tgaattaatt aaaacctacg atttaaccaa ctatgataaa
     2281 gaagttaaag gtccacaaat gagtaagact ggataccaag tgcctattca taattattca
     2341 ataaccagtt tgtttggaaa tcgtggaaat gaatttcacc gaggacttga tatggcagct
     2401 acacagggtg agccgattca tgcagttaaa gctggtaagg ttgttaaagc agagtttcac
     2461 tactcttggg gaaattacgt ggtgatacaa cacgaagatg gatcaaccgc gttatatgct
     2521 caccagcaac aatacctagt aaaaactgga gataatgttt tgcaaggaca aataattggc
     2581 tatgtaggaa gtactgggaa tagtactggc ccacaccttc atttggaaat ttgcaaagat
     2641 agtagtcttt ctcagagcat gttagttgat ccgaaaacct tattattcgg agactaaaaa
     2701 aggtaatcaa tctgacaaag taacaagaaa atggttggat tcttagacct ttgatcagga
     2761 tattgagact ggaattgata tctcgattac gatgggtttg acaaataaaa caagtccatt
     2821 atcgaatatc gagtgtatta ttgccgtctt tatgctcata ttttgagcag gtttcactag
     2881 atgaaaacaa tttatctatc ttgaggattt cgtgtacgta tcgttcagtc ttgtattgta
     2941 aattagtcat aaaatcagac taagaaaaat tggaaatatt tttttctgat ttattaaaag
     3001 ttaattgaaa ttatatggta cttctttctt gggagggtag gtgcagtgaa ggaaagatat
     3061 ggtcacctta ctgttgttga ggagattact cataatggat ataaaaaata tcgttgccta
     3121 tgtgactgtg ggaatgaaac gattgtatat cgatcaaact tactatcagg tagaaccaaa
     3181 agttgtggat gtggaaatta taaaaatagg cataaatata aaaatttgac aaataaaact
     3241 tttggtaagt tagttgcaat caagccaact aaactgcgaa gtgaaggaac tgttgtttgg
     3301 gaatgtcaat gtctgtgtgg gagaaaaaag ttagtatcgg caaagcgact tctaaaaggt
     3361 gatgtaaaaa gctgtggatg tttgaaatca aaaaagcatc acattgaaaa taaaaaattc
     3421 ggattactta ctgcaaagta tcctttggac aataactgtt catggaaaac aaaatgggtt
     3481 tgtcattgtg agtgtggcag tatgtgtgag ataagttata gtaacttatt ttttggacat
     3541 actcaaagtt gtggatgttt aaaaaggcaa gaaacaagga catgtgttga agggacagta
     3601 atagagtgtc taacgtcaaa attaccgaaa aataatacaa gtggtgttaa gggagtttat
     3661 cgttctaaag agaaatagat tgcgtatata actttaaaaa aaaagaggta ctatttagga
     3721 tcgtatgatt ctattaagag tgcagctcaa gctagaaaag atgctgaaaa taaattgttt
     3781 caacctttga ttgacaaata tcgaggtaat cattaattat tgtggataat aattaacagt
     3841 gatatataaa catctataat atattattca tactattgat atttagtata atcctatgga
     3901 attgaatatc atagcaatgt atttgaaaag caaattggaa aacaaatagg tgcaacacca
     3961 taaatatgaa aaaattggga aaaagtagaa tggaaatttg cttacgtctc acgagatagc
     4021 tcacactatt aatctgaaga acaatgaagt cgacttttag aaattgctag aagaaagtaa
     4081 agcgaattat cactagttac tatagagtaa gttcaaataa agcatctcca acttacatgg
     4141 ttacatgagg atatcaaatc gaaattactc aagcttccta tggctagagt cgcgagaagt
     4201 tgttgggcag tagacatagg ttatattgtt cttagctaca cgatcattag aaaggaaatc
     4261 ctattatgta tagttatcaa gaagatgcaa aagtccaaaa aaatcgctgg tggattttga
     4321 ttgctatatc tatgtttacc ttcatgtcca cattggatgg cagtattgtc aatattgcac
     4381 tacctaccat ctcagatgat atgggcatac caatgaatca agcggaatgg gtagtgtccg
     4441 tttatctgat gattgtctgt tcttgtttgt tgctgtttgg taaaattggc gatagccgtg
     4501 ggaaaatcaa agtatttcgg attggtacgc tgatctttgt cttgggatcg ctgttgtgtg
     4561 ggttcaatca ttcgctaggt attttattgt tcgcacgggt ggtacaagcc attggtgcta
     4621 gtatgactat ggctacaaat gccggaatca tcacggaagt ctttcccata catgaacgtg
     4681 gtcgggcatt gggagcaata ggtgcgtttg tttcattagg ctcgattgct ggaccaggtc
     4741 ttggcggctt gattttgtcc caattttctt gggcgtacat tttttggatc aatgtaccgg
     4801 tgggaatcgt aacgatgttg attgctgaaa aattcttacc aaaagatatc accatgagcg
     4861 gccatacaat cgatggaggg ggctttgctg ccattgcggc tacgattatc agcttttttg
     4921 gagcaatctt tttggggcaa gaaagtggct ttttccatcc agtccccctt gtactgttcg
     4981 taatttcagt gattgccttt gtcagctttt taaaagttga aaagaaagca gcctctccat
     5041 tgatttcttt cggtattttt aagaacaaga tttttaccat gagcttgatt acagccttgt
     5101 tgattttttc ttccaacttc tttgtcaatg tagtgattcc tttttatctg caaaatgctc
     5161 gcgggttgag tcctagctat gctgggctgt tgatgatggt ctttcctttg atgatggtcg
     5221 tcggggcgcc tttaagcggc tacctgaccg accgggttgg cccggagatt ttggtattag
     5281 taggcttggg cttattgtcg gtaacccagg tcatgtatat gtttttgtca gtggactctc
     5341 ctttgtggct atacattgtc gctactgcca tcatgggtgc cggcaatgcc ttgttccagt
     5401 cccccaataa tacgatggtt atgagctcgg tcactatcga aaacttggga ctggcaggct
     5461 cgatgaattc ctttgcccga aatttgggga tggtcagcgg gatttcgctt tctacgacgg
     5521 tcttatatca agcgatgtct gctaagatgg gccagcaagt aactaactat atcgcaaatc
     5581 ggccggatgt ctttttatat ggaatgaaga ttaccttttt aggcagcttt gttttgtgtt
     5641 ttgttgcctt tttcctgact atctggcgta tcaaaaaaca aggaggtatt cagaaaaatg
     5701 tctgaaaaaa ccactgttga agaatttttg gaggcctgcg tatgggtgag tgggatttcc
     5761 atggatgatg gaagatgaag tgaacttcta aaagccgaaa aactcaagta ttatcttcaa
     5821 aatactagtg ctcaatgaga tgcttgattt gatcacaaga agactgcgaa agccgctggc
     5881 aaccgcaagc taggtatccc accgatggac tacgttttag aggctactgg ttatgaatac
     5941 ggagccaacg ctctcatctg cataagaata catcacccag attatgtaaa gattttcgat
     6001 acttctgtca aaaaatcatt aagatagata aatgatttcc gtctagtcaa attggttcag
     6061 aatgtagaca cacagatggt aagaagtcac tcacaattcg agaatggact tgtcctattt
     6121 gccgtataca tcataatcga aacgtcaacg atagtatcaa tattttgacc aagggctatg
     6181 aatacaagca ttgccttaga aaacatcaag aaccttagga acaacgggga tagcttggtt
     6241 aataagagat accgctgttt aggcttgcaa gtatactctt ttatcaagaa ttccgtggct
     6301 ttagtcatga gaggcttaat actatgaaaa ttttctttag catttttgat ttaggttcct
     6361 tttctaatta taataagatg accactacag taacctactg aaatatataa acagccactg
     6421 tagtaccatt ttcaaagtag tctatgagag gagaatcttc attcttatga acgctggaat
     6481 tgcggatatg aatttaataa aaaaaaccct taatgatttt acttccaatt caatatcaaa
     6541 aggtactggt atcaatttaa gcacaataaa aaagctgaaa agtggtgaaa gatcagtgga
     6601 aaagctgaat cttttagatg ctataaaaat aacggaattt gctatgaaaa atggaaaagc
     6661 tgagattgaa atatggagat aattatcgtc tagtgaatta cttgccactt agctgaattt
     6721 aacgatcctt ggtgcttgaa gggggagatt cttgggaata gagcatactt gcaagcctat
     6781 gtctttacta acaacgatat ctcttattaa ccaagctatc cccgtagttc taaggctttt
     6841 acttttatct aagcaataat cgtattcaaa ggaaattttt gacccttaga aagtctcatt
     6901 ttatcagacg tgagcttagg cattgctgaa ttttgttaat tcggttttag gttgtgcttt
     6961 gagcataata tgaaagtatt ctttatcacg atttcattca tctaaggtaa tgtgatgtga
     7021 ttctgaaatt ctttcaaagg cagtttttgc ataagctgac attacatcat caatgacatg
     7081 tttacaatgt ttcactacta aaataagggg gtaaccaaga agaaaaactg aatgattatt
     7141 tgtatctaat tccatggtat atcaaccatt tcctatatag actgattatg acatggatta
     7201 aaataaaaag gcactatgtc ttaattgtcg gttttcgagt taccgaatgg cattcatcac
     7261 ccacctatag aggatgggcg acttctgcct gaaataagtt acactactta taacttctaa
     7321 taaaattaga ttgagtcatt attatttaac atcaacgatt ttccagtttc catttttttg
     7381 taatactaat ttgtactgaa agtagctagt ggtttttgat acattatcaa ggtattttat
     7441 ctttgtactc actagaaaat tttttccgtt ttgtagataa actggattct ctaactccga
     7501 aaactttaag tcaatattga ttggtcgcat cgcaccattt tcaacataat actccaattc
     7561 tttttcagaa gctgatggat aaagtttaaa aaatgtttct aaaaaatcgg tgatttcttc
     7621 cgttgttttg gcatcaattt ctgaatcgtt ttctacttgt tttgcttcat attttgcctt
     7681 gtctggcttt ccaatcattg ttggcaaact agttactaaa tgattcctgt tttcatcttc
     7741 aaagattgtc actcgatatg cagaagaaat tgattgcgtc ttttttccct ctgtaatatg
     7801 ttgctccact aaaaatgaaa cgacaaattc ttccgagtgt ttttcaacat ctagaatttt
     7861 tacagattga acttcggaac tcgtgggaat atctgctcga accatatctt ggattaaagc
     7921 gagaccgttt tctgtaaggt actgttcgag attactcatt ctcttttcaa ttgcttcttt
     7981 gttatttttc catgaaaaat attctttcgc aaaatcctct gtaaaacttt caacgccaga
     8041 agtattcact accttctctt ttataaccac tttttcatga gttgtatgtt gatcaatggc
     8101 ggtgaaattt ttataaacgc caaaagcaag actacaagac aataaaagcc aaagggcaag
     8161 caccattttt cgatgcttac ccacggatac aactcgttct tttttctttt ttgggctctt
     8221 ttccttttga ttccgttcaa tttttatctt cattcttttt cctcttttct cttatttgta
     8281 tcggccagct ccgataagat gctgccgcca atagttttcc gttagattcg tccaccccac
     8341 tggatctcct gcatgaaaca tgcgattctc ccctgcgtaa atgcccacat gggtcacata
     8401 agtaccggca tcataggttg aatgaaagaa aactaaatca cctggtttgg catcttttag
     8461 atcaatatga gtcatggcat catattgatc ctgagccacc cgaggaagtt tcaggtcaac
     8521 tttggcataa caccattggg tcaagccact acaatcaaac cccgtttctg gacttgagcc
     8581 accaaacaca taggccgttc cttcatactt aaatgcctca tcaaaaattt cttggactat
     8641 tttgtcatca aactgagttg tagttaggta ttgcttcact aataaacagt aaaacatatt
     8701 gccataatta taccgccacc caccattttc cttaatcgcg attgggttgg ggtaatcgac
     8761 tttttgacca cctgattttt cctttgaaaa agattcagct aaagcaaaac tatgcttctt
     8821 cccgtttttc ccgacatgat ctagataccc gccaccatag ttataggcct gaataatact
     8881 atcttgatca caccctagtt ctttggaacg cttaaccaaa gacgcaaaat agagacagcc
     8941 ttgtttgatg gatgcctcgg tacttaatga attaggtggt aatccggctg actcagaact
     9001 ttgcataacg tcttccattg tgccaccaga ttccacttga ataatcgcca aaagaattgg
     9061 aatatactct gttatatccg attctttggc atacttttcc accattgcac ggtgtttcaa
     9121 tacttcttct gagacactag ttccgccagg agaagtgcca gaactaccat ttccctcact
     9181 gtcttcacca aacaacaaac ccacacacat caaaataccc ataaaagaga tggtcagaaa
     9241 agttaatgaa ataacaccca ctttcttcaa gttcattttt tctcacctga ccttgatttt
     9301 ggacgatggt tcattctttt ttgtactttt tgattggtct gctttggcag agtggacctc
     9361 tgtttcactt gttggaaaga atttttctta cttgctgatt ggcttttccc ttttgaaatg
     9421 atttcttgac tagttagttt tcgtttgatt tcgggattca gatttgctct cacaatccgc
     9481 tttggtgctt cttttttcag catcatatct ttctgaggtt gagctgcttt atctattgga
     9541 atattcgccc ttctttttcc ctgacgattt gttgcttcac tcagtatctt gcgtttttcg
     9601 tccattttcg catttcttcg ttgtcgttgt ttttctcgca aatccactcg atccgctttt
     9661 tcttggaaca gtccgcgctt gaattcttct ggtgcttttt tcgacttttc gattccttta
     9721 tggagattgt atttcaaatt cgttggcgta ttccttacct gatcctttac ttgtttagtc
     9781 ttatctttca ccaaagcttg ggtatccaaa actttgccga tttttctccc agccaaattc
     9841 attcgggatt gtttcttatt atttgaaact ggattctcct tagttaagtc agatagtatt
     9901 tcgtgatcgt tcggtaatcg tgaattcttt cgtagagaag aaccggatgg cttaaatttg
     9961 gattttgatt gttcctttgc caacttattt ccgactgctg caccaccacc aaaagccaaa
    10021 gctcgtccca catttcgatt gagttgccgc aattttcgat tcattaacat ttgcggtttt
    10081 cgcatgacgc gtcttcccat tgactggcta tcattactct ggaggttgaa catactcata
    10141 atgtcgccca atttgaaata gataccggca aaggtcacaa tttgcagaaa agcaaccatg
    10201 aaaaatggat aggttgccga aatattgaaa aacatcgtgg agatgctaaa tgcagtcgta
    10261 atcaccaaag taacacccgc tcgcatcata atcgtattga ataaacgaat aatcgccttc
    10321 tttcctaaac tttcataagt cggcaacatg gacaataaga aactaattgg cagaaacatc
    10381 gcaaagataa tgaagagaat ttgcgagaac aacataatcc ctgttagaag aaaaacaaag
    10441 aaggaaatgc caatattgaa caataccaaa aagaccacgg tccctaaacg gttcatggtc
    10501 ttggtaatac tgagattcgc attgtcattg tcttcaatct ctgccttgac cgcttcttcc
    10561 cgatctttgc ctttgttttc atctggactc acagatagaa tcttgttgac ccggtcttca
    10621 ccaatttctt ctatgttgga atcatcaaat tgcagtagta accaaggttg ttggacttga
    10681 atcgaaaaca aactatcccg aatcaaatcc acactatctt ttccttggct ttctgaattg
    10741 ggtacaacga tctcggttcc aagggtaagg gccgcttcac taacatctga gctaaagtca
    10801 ttgatttttg tgatataggt aggcgcataa gcaatgaacg aacccgatag tagaaaaatc
    10861 atcacaaaat taatcacggc tcgaactgct ttcgtggttt ctcgttttaa taatccggta
    10921 tacgccacat acacccccag agctaaaatc atcaataata gaaacccaaa ataaaatccg
    10981 gaggtctgga gtccattttc agtaatacca gccaatgttt ggatattctt tccaatactt
    11041 tcagccgtat ccgaaatgaa atctaatttg taagcctctt gaaccacata acccgtggcg
    11101 ttcgacaaat acaaactcac cgtccaaatg aaattagtaa tggcataaag accatacatc
    11161 acgcttttcc ctaagccatc accccaattc caaggcaacc aatcccaaga gctatccaca
    11221 aagaaatcta gttgatagtt gttcagtgaa tatttggaat atagatttcc tgcttcaact
    11281 gtatcatcaa ctagccctgt cgcctcggct accgtaccaa ctaaactcaa tagaactatc
    11341 agagtgagta tgctaataaa aacgattccc acaatccgaa aaagtttctt tttcatcccc
    11401 tcactccatt ctctcttgaa caggtggacg ggtatcaaag gcatggaaga gttcttcaaa
    11461 gactggatgt acctgaacca cgcctacccg accatacaaa tcctgcatca agcattggcc
    11521 attttccaaa tctcgtaggc gtttttgatt gctttcatct tctcgatcca agccaaagaa
    11581 ttccaaggtt ttcttgattt catgaatatc ggtactgcga aacgcaaact tcaacccgat
    11641 attattcttc aagcgttcat ccagtaaatc atcactattt tgcgtgacaa agtaaacccc
    11701 ggcattcata gcccgcccag cacgaacgag cttattcgat aatgttttcc cttgcgctac
    11761 ttgaagaaaa ctccacgcct catctaagtc tacaattttg aagatttctc gattactatg
    11821 gataaagtcc aaggcaaaag tggaaatgac gattagcatg gaaacactaa gcaattccat
    11881 ggtggtatat tcttcaaaag tggtttctgc atctggtaaa accaaatccg ctacttgaat
    11941 gatatttaac tgcctatcta aactaatcga ctgggtaatc gaaccatctg agaaaagcaa
    12001 atgggcaaaa tcataatcgg taaaggactc gatgtgatcc gcgatatttt ccgcaactgg
    12061 tgagccttct tttcgaagct cattaattac ttgtaataat ccccgttgat tgctttgggt
    12121 aaccgtccga atggccttac gcaacactgg aaacttctcc ccatctcgac tagaaattcc
    12181 tgttaaaaag gtcagaatat caattgctag actttcagaa tccttctttt tctccataat
    12241 cacataagga tcaagtaatc cttgattttt tggcttacta gttaagttga gaatattgat
    12301 ttcatccgca atttctggca aggtttcttt ccagccaccc cgttcccctt ttggatcgac
    12361 aatcacagct tgtccaccaa aaaggacggc gtaataaact aagagattgt tactaaagga
    12421 ctttccgcca ccgagtgaac cgaggaatgc cgctgctagc gcattggtaa ctgaatcctt
    12481 gaccccttgt gaggccaatg ccggtttcag gtaaacattg cgccccgtat ctacgttata
    12541 accaaagtaa atgccttcca actcccctaa catctgagtg gcgccaaaac caagtccggc
    12601 gagaaaatca gacgtaacat actggatata atcattcatg tatcgcttac tagaaggtaa
    12661 gaattcttca tgtagcccca tcatatcgcc aaaaggccgg actagtttta cattggtatc
    12721 atcataaaaa tctagcactt catcacaccg gcgctttagt tcatctactg attcggcact
    12781 tactcgaacc acatagctca gtttgtacat ggattctttg gactgatcca aggtagtttc
    12841 caattcatct acggaatcca atgcatctaa gacattggaa tttgtttcat tgtcagattg
    12901 ataggcatgg ttgtccaagt cttttaattc ctttttctta ttgcgaacgg tagcaagtgc
    12961 ctttttgttc gtcacaatct ccacattcat actagtgtca attgggaatg taaattgttg
    13021 ttgctggtaa tagaaaagtt ctgaggaggg aaactccatt tcccccacaa ttgtattaat
    13081 tgttaagtac gctacatatg attcatgatt ctcatgttcc atgcataagt accggggctt
    13141 ttcttcaatc aaacaacgac tgggacgtaa taagtcgtaa cgtttcacca aagtttccga
    13201 cttcagcttt ttctttggta gctgaaattc atattcttca aatggtgtac ccttttcgcc
    13261 atagatatgt tcaatcaaat acatcagatc actcggtgtg actcgtctga ctttaaatct
    13321 tcgagccaat ttactttcca ttagtttttc aagcttggta tatcggcgaa tttcttcatt
    13381 ggataaggaa acaaaatcgc ccatcaaatg atgattcact ccatagacaa attcttgaaa
    13441 gccggagaag aaagatttct tgagattctt tagattgacc tcttcatctg tcgcaatcag
    13501 tttgaagcca ataaaaaagc gataatcaat ctgactatcg ccaatcatgg atactaatgc
    13561 ctctgtctgt aaatcaattc gttgtttcgc tacttctgtt aatcgcccgg taatttcctt
    13621 ttttgatcgt tcttgcgtgg cacgaatact actttctgtg gcaatttgta aggcatgaat
    13681 cttgccttca cgattttgcg caatcaattg acgaaagtta tcgtggactt gatatttctg
    13741 ttcaggtgac aaaaaggagt aattgtaagg tattaactca tagtaggcaa aacattctcc
    13801 ctcttgatta aagacaagat tattttcaat atacttaatc gggtacatag ttcacactcc
    13861 ttaccagagt aatgggttcg tcccatcgtt tcttctgttc tttgactttc tttcctgcga
    13921 aagtgacctt aaatcgtaag tgatagctaa taaaagatcg taaaaatccc aatggtttct
    13981 taccgtcaaa cgttttttgc gacatgaacc aagtaactgc caccggtata cctaagtatt
    14041 ttaaaaaggc cccctctatc atagatagtg gaggcacatg ggcaaatacg atgacaaaca
    14101 gcaaggataa aacaaaccaa gccatctggt taaaagtcac aggaaaaggc agttgaaagt
    14161 cattaattgc ataaatgacc ttttcaactg cccaaatact ggtgtagctt tttattttct
    14221 tcatcaaatc attcctttaa aaagaaggat agtttagaaa tcaactaccc ttcaataatt
    14281 ttgttaatat ggatactcaa aaacacctcg actcgttacc aaataattgc ctccaatctc
    14341 caagtctcta ccacacgcat caaaatcaat atacgtcttc aagtgttctg gtacttctcc
    14401 aaaatcacca gcttctacaa tcaagaaata tgctacatca ctcatatcat cgcaatctgg
    14461 ataatagata atatcatcca catgctctac catctcctca aaagaattga agaaagcatg
    14521 ttgaatctca gaagcaactt caccaactgg cgttccttca agttcctccg ctaagccaca
    14581 caaccgatta atttcctcaa ttggcgtata ctcatcaatc tcaaagggaa gttcataatc
    14641 atgaattgca tattcctcgt attcgtcatt taacccaatt cgttctttca cttcatcaaa
    14701 atcgacaggt ggggtaaacc acgcccccac caattcacct tcgttatatt tcccgaggtt
    14761 cgcaatataa acacgcatct gttccatcgt gcttccccct tacgcaccga caattcggtt
    14821 aaacaaactg agtaagacat ccttcacccc agaagcatta aagaccaatc cgaccgcaat
    14881 caaagcaatc accaaaaagc caatcagttt ggaaaactcc cgcttaaatc ctaaaaacaa
    14941 accaatgacc acaattgcca gtaagactaa ggattgggca ttggttaaaa accattgata
    15001 tatggatagg taagttcctg atattataaa tatctcaaac ttttcccccc attcacacgg
    15061 agcgtgcgac tttcaccgca ctccgcgttc catcgtgttt atattgaaaa gtatttatgt
    15121 agtagaccta tatcaagttt aattcttgat tgccagctaa tactctatat ttatttagtc
    15181 ttatgagctg gactttattt agcttcaata gagctatata tttttgtatt gtttcttctg
    15241 ttttagcgtg tattagacgg tgtaccgcct cttttaccaa aataagattt ttataatcgt
    15301 catttccacc agctccagtt ggtacaatat gatgacaatg tatttcatta gcttgttgaa
    15361 attcttccag agttatagca cattttccat gttgagcaga aaatagcgaa attcgattgt
    15421 ctgcgtattc tattgtgcga ttttccaaag ataatttcat taactggtac atcagtaatt
    15481 tatcaacact tagattggtg tggataaatt ttcttccctc tagagtgtag caattcgcta
    15541 aatacacctt tgccattggt tttctgtgtt ggatatatcc aacagggaaa ataggttcgc
    15601 cctcgccagc aacataccga agcattttag atttaccata tcttgttgcc tcctttgtcg
    15661 taagttgtct gcctgttttt ctcaatctgc cccttttgtt tgtacctaat ctgttagtga
    15721 agatagccat tacagctcta ttcagtttca tacaatccag atttacattc gttgcaatct
    15781 gataataatt ttgcatacct aataccattg aattataaag tcttgtttct tctaattccg
    15841 ttttcccttt tgagggagaa gcaattttct ttgcctgtga taccagcttg tctttttggt
    15901 ttttgaattg tttatcactt atatgtgatt taacaactaa cttctttctt ctcggtatca
    15961 ttttaatctt gaaaccaaga aagtcggagt atctttttct aacatttaca attcttgttt
    16021 tttcttgtga tacttccaat tttaatcgtt gttcaatcca ttgagtgatt gctattttgg
    16081 ctttttcagc actttccttg tagcggcaga aaactctaaa atcatctgca taacgaacca
    16141 tatacatttc ctttaacttt gttttcttca tttctttgta agcgttgctt ttacatgggc
    16201 taccgctttt attgatatga accacatagt tttttgtaac aggattttcc tgccattggc
    16261 tttctaccca atggtctaac tcattaagaa caatgtttgc tagtagtggg gatattattc
    16321 ccccttgcgg agttcctttc tctggatatg ttattgtacc gttagtcatt ttgattggag
    16381 cttttaatat cctttttaaa atgaatatca agtgcttgtc ccgtattccc atagcccata
    16441 tctgttttat cagcttggaa tggttcacgt tgtcaaagaa acccttaata tcaaattcaa
    16501 tcacataatg tagctggctg atttgtaggc ggttataggt tgcttttatt gcattttcaa
    16561 ctgacctatt aggtctaaaa ccatagctgt tttcactaaa tttagcttcg cagattggtt
    16621 ctaatacttg ttttatacat tgttgtataa gcctgtccca catacaagga atacctagag
    16681 gtctggtttt accatttggt tttggtattt cttttcgcct cactggctta ggtcgatacc
    16741 catgtggact gcctgcaaca atgtatctta cttttttgac aactgtttct gctggcaatt
    16801 tgccaatatc tttaattatt gtaccgtctg ttcctgctgt tttactgcct gcatttgctt
    16861 tgatatttcg atatgccagt aatatatttt ctctcgatag gataatatcc ataagatgag
    16921 tgaaaatatc tccattctta cttttggcat ataaatcatc aaaggtgttt tgcatttcgt
    16981 aatattcagc gtgtcttaaa tcttctacac acaatgtttc atttttattt ttaggcataa
    17041 ggcttcactc ctttacttga aattgagtga gcttttttat cttactcgta atccttattg
    17101 aaacaacata atacttttct aatatataca cgacttgagg gcattcctcc attctcatta
    17161 caagaatttc ttaggttcgc cctctgcttt tcagcattag ttcaactgct tattgttctt
    17221 cgtcagttta ttctcttgat gagaacccaa tacctttcct cgttccgata atcttatcta
    17281 tacatatata tccttaggtc actagctata agcctgctgg cttgataccg cctgtaacgt
    17341 tatatggcat ttcataacct atattcttac tttgccacac cagctacgat ttctcgtacc
    17401 tttgcatttc tacaaagttc aaatttagac ccgtacattc gctgtttcgt cagttcctta
    17461 tagaacattc taaccataga tattttatag acccccgacc tgttggatac gctacccacc
    17521 tctggatagt tttcgataga agatatatgt tcatcaacta ttacggtatc tttcagccgt
    17581 ctttaccgag cttcaaacat tctgagtttc ctcatacaat gcttgtcgga ggctcagggc
    17641 aggcgtttca gagcgttact tcatcattcc acctgtcaga ttatcagttc tcctaataac
    17701 caaacttttt cgttctttta ttagtgcctt agcttttcac taaggaacga gtcgcacata
    17761 aattttgtcc gaaattcatc ttgtcacttt cctttctttt ccattgctcg atccgctgct
    17821 gcacttgcat tcatcaagca catcacagta acaccaagca tactgccacc aaataccaaa
    17881 aaaatatctt ttacaattcc catgacgatt cctcttttca tataatcaaa ttttcaattg
    17941 ccatactttg ttgctccaaa atctttttat gtcggtctga taagcgtgca ttctgtacca
    18001 tatcctggat ataggttgtc cgattcaatc gatccaactc cttagccatt ttccacgtag
    18061 gggcgacttg tcggcctagc caattcaagg ttcgttcaat ggtatacggt tttggctcgg
    18121 aagttaattg aatctctttc cgattccgtc caataaaacg cccccattgt tcattcaagg
    18181 gccagttggt tcgcctttta ccttctactt tatccgcaaa tcgcaagtaa cgattgataa
    18241 tggaaaacgt ggtgctctca atgctacgac cttttaacaa atcttgaatc gcatgaaaag
    18301 cacggtcatt tttcagtcga atctcaaaac gatttttcgt ctcagtttgg tctaatggaa
    18361 tccctaactt gatatattgt tcatagtctt tttcatacaa acagaaataa acctcactct
    18421 tgagactgcc gatatataag gtattgccca tgccgtcctt ttcatcagcc tttaaaagtt
    18481 ccccggaacg ataactttta aaggtacgaa acaaggagat acattcttcc ttctgacatt
    18541 ttttcgttag ctcaggtata tccaatagcc ccactcgatc attgattgcc aagtccaagc
    18601 gtttcatcac gccaccggcc tttagacaat cctcgaaaaa gtcgtaccag ctacgctttt
    18661 gagcgagtaa aaaagtttca aattgtcggc aacctcgccc ctttaattct aaaagcacac
    18721 ctttatcttc ttcatgagac aacatcacca caatatcacc catgacatac tgttcttgat
    18781 aggagtaaaa ggcataatct tcatggagca tatactcaaa tttcaaatgg agaatttctt
    18841 gaataatttt tcgtgcatcc gttgtgggaa agcgaatcct tacatagtca aacagtaacg
    18901 tcaaaggcaa atcgggatta aagctttcca gttggtcaaa aattttcctc atggttttta
    18961 tagatgcggt tacgccacca ttttctatct gatttaagta cggccgacta agtccacaag
    19021 ccgtagccaa tttattttgt gaaacgccgt attcgttgcg tcggtctttt aatagccgat
    19081 aatctaaatt ccgttgtgcc aagttctcac ctccaaattc aaggtgttaa ctttttcaaa
    19141 tgagttaaca cctatacaaa ttacttacta tctttgatac aacaagcatt cttaatggtt
    19201 gcttacttat tttttgtgtt tttgtacccc cctgttagat acgggggtga gacatcatgg
    19261 tcggctaacg ccgtccatga acaggcacag caccacggag gatttctgct tcgcgaatcc
    19321 tccgcggtca gcgcctaaca gtcagttgtg ttggtttagg ttactcatct gtaataccat
    19381 ttacttccaa ctctgctttc atttctaaca agtattgacg aatatctggt tcttttgctt
    19441 ggtccgcaat ccgctcaaat tctgcaatta cttgatttat ttcaattcga gcatccgtct
    19501 cctcattcat taaatatgga tcgccagcga ctttgacacc attcttgcga atatcaaatt
    19561 ttaaccgtcg caattgttct tctaattctg ggtctgactg aatctttcca atcacccaat
    19621 aaatttctcc aatcaactca tcataaacca tgtacatcca actcttttaa tcttctggca
    19681 atatcaaaaa tgaccggaac tgttacagag tttccggctt gcttatacaa ctgactatct
    19741 gaattgactt gagaatctcg atcaaaagcc caatcgggaa agccctgaag tcgccaacac
    19801 tctctaggtg ttagcttccg aatttgatac tgatccgtga cgatcgcttg ttggtctcct
    19861 gttagtaagg tatgaacact ctgttttccc agacgacctc ggcgacttgt ggaattagga
    19921 aaagccagat tcacactgtc ttctggcttc acctcttgat attctgtttc attttttcga
    19981 atcatgattt ttgtaccacc ttgtttcgtt gacaaggtgg gggcggttcc agtaacttca
    20041 taaactcgat taccttgttc aaactttccc ggtaatagtc ctgctacaga gattccatcc
    20101 cttgctggca gtgcgatttt gattccttca tcacctgtta aggttggcgc tacgccatct
    20161 gaaccataga cttgtccacc cattcctcga ttggaaggat tgatatttac caaatttctg
    20221 atgttttgat cagatgttga agacggtcca atgataggaa atacttgttc ggtacatgcg
    20281 tctcgagaat gtccgataag gaatatccgc tcccggcttt ggggaatgta ggcctttgag
    20341 ttaagcacct accactccac gtcatacccc aatccatcca gcgttcggag gatcgtctcg
    20401 aacgtagccc ctccttcgtg attgagcaat cctcggacgt tctcaaggaa taaaagctta
    20461 ggtcggagaa gagtggtgaa ccgagcgatt tcaaagaata aagtacctcg agtatcggaa
    20521 aatctttgcc gctttcccgc aattgaaaaa gcttggcacg gaaatccgcc gcaaaggatg
    20581 tccactggtc cgagggattg aataaactca tctgatacac ttgtgatgtc atgcatttcc
    20641 acctccttac ttgtatcatg aattgcttta taactacgtc tagcaaattt atcaatttca
    20701 caaaaaccga tacaatgatg gctcgcctgt tccataccta aacgaaagcc accaataccg
    20761 gcgaataaat ctaaaaatct catacattac ctcattcatt gcaaagaaaa aagccaagaa
    20821 cattttgctc ttggctcata cattattaat ttgtcctact attttttatt taatccaact
    20881 aatttccgtt gtttttcatt ggcctgatcg gctacatatt taatcaccgt tttgaactct
    20941 tttgcagtag cattttccga taaatccgca atgctcttat tgtatttctt tacaattttc
    21001 gttacttgtt ctttctcagt catgtaattg aacctccaaa tctttcctac tataccctag
    21061 tggtaaaaat aattctagat tatccgtagc ataatgaact tcggaaatat tattcgtata
    21121 atcttttatt atgatatgaa gcaatacatc tggatgttta ctctttactt ttgcaatgtt
    21181 ctctcttgat ttgaaaaaag cgttaataaa tgcctttttc ggcacatgac gtccctctgc
    21241 aatttcacgt tcttgtgtaa atttccaagc gattttaggg tcttgataaa catagaaaat
    21301 cgtcactcga aaatgttttt tcaacgcccg cgagatattt ttttcagcac ttaatattgc
    21361 aaaagttgca tccagaataa aagaatagcc atgatctaag acatatctaa atgcctgctc
    21421 taccaaccaa gaagatgctt tttgaaagag actagagttt tttccattat aatcaggaaa
    21481 ctgggtgcga aagtaatccg catcaataat cacatggtta tcataattct cagctaatcc
    21541 aatggcaacc tctgattttc cagccccagg actccctgcc ataaaaactg cgtctcgtcc
    21601 aacttcgggg gatttccctt tgataatata agaaataaac ttatccttat ttgcttttgc
    21661 atactctaaa taagaatcat tactttccat attaattatc ccctttcttc ctactatata
    21721 aaagtattat acgttacttg aagtataaag tcagtattga agatcactca atcattcatc
    21781 ttttctaatt tactaattga atctaagaaa tcataccctt ttggtacaag tggcgtataa
    21841 aactcactaa tcacactgcc acctgtatcc acataacctc gacctttgat gtgcttcata
    21901 aagaagtttt tttcgacctc cccaaacatc atggaatatc cgagttcact catacgaccc
    21961 aaagccacgc gaaagttgaa ttgatcgcgg attccgtctc ctaaatattt cgcatccggc
    22021 ctttggcaag ccaaaatcag aaagaaacca gattgacgac ccaacatcac gatttgtttg
    22081 agcttattca aaatcaccgc actttctttc gtcgttaaca tctccatata agccacgtat
    22141 tcatcaaaga ttaaaaagtt gggtggaagt ccaagatagg cataattctc tcctgttttg
    22201 tagttagaca tttctttcat tgccttgcta cgagccatca tacgttcata gaaatcttcc
    22261 acacaagcag aaatttcttc cttttgtgaa taaacatgag gcatcaccgt acctaaatca
    22321 gctaaatctg catttttggg atcgaggata aacaattctg catctgactt caatagtgct
    22381 tcgataatgg tgaggaggaa ataggtcttc cctccacccg tgccaccagc gattaacata
    22441 tggggtaaag aatcataagc ccatacttga tttttcatca atcgcagagt cccattttct
    22501 gccactactt cgtctatccc aattcgattg gcgatcatat catacagtaa agtatactcc
    22561 acataggagt ctttgagttc cttttctact aactcacaat acagtccgct ttctaacttc
    22621 ttttccaatt ttaaaagctg atcttggtat ttcccaagtg aaatttgaac gcgaatagac
    22681 agtaatccat ctttcattcg ataacagatt ttggggaagt aactgatagt ctctctggtt
    22741 cggctactat tcaaatcttt gaaaaagcct tcactttgag tttgtttcac ttcataccaa
    22801 tggttctcta gaatcatccg agctagcttt tgtcgatgcc acaagcttcg ccaatgatca
    22861 agaaaaaagt gaatataaag caatatcata gctcctgaaa aagcgagact tccaagcaga
    22921 catactaaat cttttataga ccaaacgatt tcaatagtag aaagtgatag cttagaaata
    22981 tcaaattgtc taaactcttg aaaataaaag acgctcatcc aaccgatgaa cagagcgagt
    23041 agccagccaa gaacaaagtg ataaaccaag tgctgatctc ctgcgcgtat gcgatgtcct
    23101 ttgtacattt tgatggtttc cacctccaat cgaaaaagcc caataggatt tcattaggca
    23161 atttcaaaaa gttatgctag tcatttactg ctacgaggag gggagttgtt tcgtttcaac
    23221 caattgattt aaaaagcctt caatagcatc cggcatctcc acaccaattt cttccaaaat
    23281 ggattctgcc tgccgacata agttttcatt tacttcgaca actataaaga aagactcttc
    23341 ttctcctaac cagtctagta catcagagtc ttcttcactg tcgctatttt ctccaagtaa
    23401 accttgatgt ataatcagaa acattttttc atcagaggtt aatgctttaa cgagttgttc
    23461 ctcagtcagc tcgccttttc catattgatc gagacaatct aaaatatgtt caacattaat
    23521 ttccataatc ttcacctatt tctttctttc attttggttc gtaggatttc cttgattcgg
    23581 ctgccgcttc aagactaaat catccgcctt aatgaaccaa ttaacggtag ttccttctcg
    23641 aaaaacataa ttggcaacgg tatccacgat tggattgacc aactctacct ctgcatcata
    23701 agcaaactcg cgtaagggta cattagctgg gatactaact tgaatcattc gcccttgtgc
    23761 agaggatttt aaattatagg ttcgttcttt tacctcatta ccaattgttc catcctcatt
    23821 ttgcttccgt acttctcggc gtaatgcgga aaaacgcaac ttcccaaatg ttaaacctga
    23881 atctacgaca ataccttctg ttaatctcat cttcttttcc tcctatgctt tcactaaatc
    23941 atcaacatac aacacgtaat cagtaaaccc acgattctca atctcatagc ctttggcaac
    24001 caaatgggga ttcacggctt ttagcggttg gtcttgatca aaatcctttt caccggcttc
    24061 cgcagctact accacctcaa tatcatcggc ccgttgctta ctggaataca aatgataact
    24121 gcgaccaatc accgtagtat tccgtccata tccttctgtt ataatttctc cttcaccggc
    24181 ataacttaac tttccaaagg tttcagccat atctggcacg acaaatttca attccatctt
    24241 cttttcctct tttcattgtt agttttggat acaaaaatag cgcgactact tttttaggag
    24301 gcggtcgcgc acgttggttc ttaggattta cttgtatcat ctcatcacct tagttccggc
    24361 gattccagaa ataatagccc gccgtcgcaa aaatcaaagt aaaaccaatg aacagtaaaa
    24421 cattggaatt tttctccccg gtttgaggga aggtcttcac tgtgggacta gattcttgag
    24481 agccacttgg aacagttggt gtttccggtt gtttcggcgt acttagtatg gttggaactt
    24541 cttttggtgt taaggtttga gatttttctt tcaaatcttc attgtgtttt ccattgatat
    24601 tcccatcttt atcgtaattg atttccgcaa aagtaaactt ggttccttct ggatattttc
    24661 cggtatctac ttttttcgca agcacagttt tggtgaattc tttatcattt acttcataat
    24721 caatcttgcc agatttccaa atttctttgt ttgtaccatc cggtaataaa gcatacagaa
    24781 ttgtttcgaa agcttctttt gagccatcca gtacatcatg agtaatcgac acatcatcaa
    24841 acatatccac cacatcacca tgagtaaagg tctgagaacc gttttctagg tgggcctttg
    24901 tttggataga aacatggtgt tccactgtac aactgacagt ttgggcttgg ttattcaagc
    24961 taacatcctt cgctactggc ttatcgcctg cttcaaaagc ttccttattt tcatacacat
    25021 agttgaataa gacaatagtt ttatttaaaa cttgttcggc ggttaattta tgctgaattt
    25081 tccaagttcc tgttttctct ttgttcgcca acgttgcgct tgtttctgca atcaccactg
    25141 gtttggcttt ttcatctttt tcttgggcag cttttgtcgc atccacatca atggcttgcg
    25201 ctaccacata ccagtcttct ttgatttcat gtagattgta actcaattta tcaactagct
    25261 cggtagaatc cagagaagtt aattctttgt ttccgtcttt ccaagtcgca agagaagtta
    25321 aactatcttc ttcctcaggc aaatcataga gcattaaacg gttcaaacta acagaaaatg
    25381 ctttgttcgt cagcttctcg taaggaacgg tcaccgtttt aattggttgt ttttggtctt
    25441 gttcggtaat ggtaaagaca tactcactct tcacaaagtc ttctttgttt tccttaaaag
    25501 tagaacggat ttctaatggc gtaatctttt gaaaaccttc tggggcttct acttcttcaa
    25561 gtaaataatc cccataagga agattttcaa acttgccata accatcaaac cctaattgct
    25621 cgttataagc tgtggtcgct tcatcttcgg cacctgtgat ttcattggtc ccttccaatg
    25681 gcgacacttt aaaggtcaga tcattgaagc cagtttcggt agtgcccgca gctgatccag
    25741 caaatttaaa gaaatcaaag ccaaagcgaa tcacttgttc ttttgccgta acatttcggg
    25801 taatcacggc atttttttcg ctatcatcca cctttttgat ggatacagga tactttgttt
    25861 catcaaggct atatccttcg ggcgcttttg tttcttgcca ataatactcg ttgatagcta
    25921 aatgtttaac ggcaacttgg ttcttttcgt ctaaagtcaa agtgaccgtt tcatcagaac
    25981 ctttcgttcc cttcgctaac tctggtttaa aagcctcact ccatttaaca gcttttccat
    26041 ccttagcagt aaacaaggtg tattcagcac cctcaaagac tgccttacct tgtgctttat
    26101 ccccagtatc tttgtcttct ttcgtcaaag tggtttcgcc agtgacttct tgattttgcc
    26161 cttttacgtt actggtaaca ggggctacgg tttgattggc atacttcaat tcgactttta
    26221 caggtttgaa cgtattcacg aacccatgac tagctttagt ttcggtcaca taataggttc
    26281 ccaattccaa cgcattagca atctcttttg gtgtttccgc atgaccgttt tcatccgtgg
    26341 tcatttcttg aacgatttca ccggttggac tgtctttgcg aatggcaaac gtattaccag
    26401 ctaaggaata attgtcattc caaagatcac tccctgtttc aactccgctt ttatccagaa
    26461 tgatttgccc tttttcccgt gcgttttttg aagtcacgta aatggtttcg cctgctttaa
    26521 tggtggtagt catgggggtg gtatcaatcg tataaggcgc cggtactgat ttttcggtaa
    26581 tggttacttt tgtaccatga ggaatctcat ccaatgtagc aatgccttct ttgtcagtag
    26641 tcacgtcttt tgcaggtaaa gtttttccaa agtctaaatg gaaaaccgtt cctggtacaa
    26701 catcacccga ttctttatcg acttttttga tctttaaaga accctccgtt tccacatcaa
    26761 ttttgattgt gtaggtatta ggtttatcaa tcgccccggc cattaaagtc tgttggccag
    26821 cctttttata ggcgacaggt gttccggtac cagcagattt cttaagcgtc agcacaccac
    26881 tttcttttga attggcattt ggggtgatta tcaactgatt accattcaca cgataatcaa
    26941 tgtttgcggc attttccaca acctcatcga actctgacaa attcagatta ttcgtatccg
    27001 tcacagtagt cgattgccct aatactgttt tagccgtact attatggaag gttggtttct
    27061 tctgataatc gtcaatggct tgatttattt ttgcctcaat ggctgcgata tttacggcac
    27121 taccatctga tcgttttatt gagtgaaggg tatacccatt aacttcttgc cagatcatct
    27181 tctgtgccac aatatgagta tctgcatctg tacctacttt tttccataaa acggaaacta
    27241 atttggcttt atcggacata tctggtaacg ggtttttctc atagccagga gtgaactcat
    27301 tgtaaatcgg gactcctggt tcaatacaga aaatatcttg tttaaagccg ttgtacactg
    27361 cataatgcgg aacagtgact tctgacattg gacgaccatc actaaaagtt ccttcaacag
    27421 catattgatg tgctaaatct agttctacgg ttaccgtttg tggatgggta atttcatcag
    27481 caaaagtaat cgtaggagca attgctccaa caattgcttg aacagccaaa ctcaaaatag
    27541 ttaatacaca taatttcttt ttttgttttt tatacatgaa atgttctcct ttcaaattaa
    27601 gcacaaaaaa ataagatgct cgcttgaaca tctttgttta taaagtcttt ttaaaatttt
    27661 tattgactga atagaatgga tttgagaatg aatgagccta aaaatttaat ctaaaatacg
    27721 aaatatactg cctttaaatt agaacacatt ttagaacaca aacatttcaa atttaatcaa
    27781 atataataaa atatatttac gggaaaacct ttataaatca aggtttttca aacttattca
    27841 atgatacgaa gaaaaaacca ggtcttaaga aagcccgtaa agcttcacag ttctcaaaac
    27901 gttaattgcg attatcgttc gagttcacga gttacgagaa tcgtactggg cgaagcaatg
    27961 ctgagcgcag ttaccttaat cctaactttt ctggcacttt ccacaatttg gaaagtgcct
    28021 tttttgtgtt tttagctatg ttaataggta ggattcttgg tctataatat cattcgatct
    28081 ataaacaaac gggaaaaaga taaagtatca tcaaacaata ttatttatcc gcttctgagg
    28141 ttgtgacaga agtggtcagc ttcaagaaat aagaaggaat ttacaaaaat tgcttctcat
    28201 gtttgataaa tattgtgact tgtgaccgag gagttggcag gagaacaccg tttattcgga
    28261 agaagggatt gtgaaaagtc ttttgtcata acctcttatt tggtagctaa ttgtaaatcc
    28321 caaacggcat gtattatttt tcataagtcc gtttttaagg attaatgttt tcttttgctt
    28381 tttatatggt ctggcttcag cgagaagttc caacgcatat acaaggacga cttatgtcaa
    28441 cgataacaac gattaccatg gtggccagtc cacttggatt agcactgttt ggtgcgctct
    28501 ttgattggaa gacaacgcaa ccacgtctgc gagacagtct aatttttctg ggagggagtc
    28561 ttgctatagt tatccttata accggtctgg taaaattact caagcttgat ctgaaagaag
    28621 caaaaatttt cagtgaagag gaatacagag aaacgacttt ggtcgaaaag aaagaatcag
    28681 gaaactgata caagcgtata acaaactgcc tgataatagg aaagacacgt attgtccgat
    28741 tgtttttttt gacattcaat tggaaaattt acactttctt tatacatttc tggctgcttt
    28801 ctttataccc gtcaactata cttcactcat caataagaaa gaaggataag tatggatttt
    28861 ggaaatgaaa cggtcttgaa agcaactggt ataaccaaaa aatacggtgc tgccaaagca
    28921 ttagataaag tatcaatcga aatcaaacgt ggaatgatct atggattgat tggggaaaat
    28981 ggagcgggta agtctacctt tatgagaact attatgggtt tgatctcgat tgatgaaggt
    29041 tcgatcgaat tatttggaac gacggatttg caggcagcaa gacgacgtat gggtcaatcg
    29101 attgaaaccc ctgctcttta tccagaatta actgcaagag ataacctacg tatccaagca
    29161 gcgaacggcg gtgtgtcgga tagagaaatc gaagacctgc tgaaaatgat gcgattggaa
    29221 aatacaggga aaaagaaagc aaagaatttc tctttaggta tgcgccagcg tttagctatt
    29281 gcaaatgcac tgatcacgaa tccagaattt ttgattttgg atgaaccgac gaatgggatg
    29341 gatccagcag ggatggcaga aatgcgagaa atcatccaac gtttggtaaa agaacggggc
    29401 atcaccgtct tgctttctag ccacttgcta gatgaattgt cacagatcgc cactcactat
    29461 ggtattttgc atgaaggaca cttgatcaaa gaattatcga aagaagaatt ggcacaagaa
    29521 tctcgtcaat ttataaaaat tgacacttcg gcgacggaac aagcagtaac ggttctcgac
    29581 tctcttggtt atagggatta ttttgtacaa tctagccgtg ttatccagct ttttgaagga
    29641 attgaccaag tagcagccat caatcaagca ttggtagaag caaaagttcc tgtggatggt
    29701 attcacctag ttgggcaaaa actggaagat tatttcttac aattaactgg aggcaatcca
    29761 catgtttaat ctattaactg ctgaaaaaat aaaagtatgg aagagccgta aaatgtgggt
    29821 ctcactagga ctgatggtcg tacttccgct tttttattct tggaacgaat ggtatatgca
    29881 tacaaaatac ggcaatgaat taaaccaagc aacggataca gtcatcaacg gtgcaacagg
    29941 gattttaatg gtagaaaaaa tggctgcatg gattcttctg gctttcgcag catttgcgtg
    30001 cttttatatt ggggaagaat ttcaaaacgg tacgattcgc aatacgttat ctttaggacg
    30061 gaatcgaatg acttattatg tgtcgaaact tctcgttacg cttttgatca caacacttgg
    30121 cgtggttttg atcacgggac tagccatgct tgcttacaca cttgctttcg gatttggtga
    30181 agttgaggga atcaaaaact atggaaatta tgttctaaaa gtatttcctg tattgcttct
    30241 gctgacatta gggacattat ctgttccagt ggctttgaca ttcatcacta gaagtaccag
    30301 tgtcagtttg cttctttctt ttctttatat catgggaacg gccttcattc ccggtgtttt
    30361 cgcaaaaatc aaaggcttgg aatttctaac ggagtggttt acggaaacgt ggctcatgta
    30421 tacggacttt gcgcaacaag caacttattc gcaagcaccg aaaatgattc tggtcagtct
    30481 agtaacaatc gtggtatcat cagctctagg aatgtttatt ttccaaaaat ctgacattaa
    30541 gtaggtggtc ctgctggaaa ctattttgat tatcgaagac gatgaagctg ttcattcctt
    30601 actggaggag gttcttgaac agagatacaa acttcttgat gcttattcag gtacggaagg
    30661 aaaattattg ttaagcacat atcctgtcga tttgatcctt ctagatctca tgcttccagg
    30721 gctttcaggt gaagcattgt tagcagaaat ccgacagaca tcgaatgttc cgatcatcgt
    30781 tctttcagca aaaagcgatc aaagagataa agtttccttg ttggcagcag gagcggatga
    30841 ctatgtgacg aaaccatttg atatcgaaga acttttgtta cgaatcggca tccaacttcg
    30901 tcatcagact tctgtccaag taaaagatct gtcgcaacgc atctattaca aggaaatctt
    30961 actggacaaa gagtcgaggg atgtaaatgt gaatggtgtg gctgtccatt tgacaggaag
    31021 agaattcgat ctgctgaagc tttttttaga acatccgaaa aaagtatttt cgcgagcaaa
    31081 tctttatgaa acagtttggc aagaaccata ttttgatagt gagaaaacag tgaatatgca
    31141 tatttccaat cttcgaggga agctagcaaa ggcacatgct gtgtatattc atacggtgtg
    31201 gggagtgggg tttagatttg attaaatggc tgttgcttct cgttgttatc tttatgggaa
    31261 gttttatttt cttcctgcaa agggaaatca agagattaac taagaaaatc gccactcttt
    31321 ctgaacgaca agaatatggt ggtcgtcttt cagtcgaatt tcgagaaaag aatctaatgg
    31381 acctagtaga tgcactgaat acatggttgg atgaaaatga acaaaaagga caagcatttc
    31441 aagaaatgga agaaaacatc agactatcga tcgtcggcct ttctcatgat ctcagaactc
    31501 ctttgactgc tattaacggt tatgtacaat tactggaaca ggtagaggat acggagaaac
    31561 gggagaagta tttaacgatc atcaaacaat ctgttgcaag attactcagt atgacggatc
    31621 agttttatga tcttgctcga atagagacga agcaaaaaga aatggatctc catacgcttt
    31681 ctttttctaa agaggtggaa gaagtatttt tctcttttta tgaacaattt tctgagaaaa
    31741 atatcgaggt agcgttcgct gaacactcga taaatacaac tgtattagca gatccgctca
    31801 tgttgctgcg agtgctgcaa aatatcatac agaatttatt gcgttatgca gatggacaag
    31861 caaaggtgac attttcaaaa gaggatccat tcattcgatt aacagtggcc aatcctatca
    31921 aaccaggaac gcaaacctct gttgaaaaag tcttccagcg tttttatacc gaaaatacca
    31981 gccgcacaaa tacggaatct agcggaatcg ggctttacct gtcaaaaaaa ttggtggaag
    32041 gaatgggagg agagatgacc gctagattag acgggggcat cttctccatc tccgtcaagt
    32101 tgcggagggt ttaattatac aagattagtg agaactagta gaaaaatgta ttatcttata
    32161 tatatttaat agagaaaaaa gcctgtgata taaatattgc aggctttttt attgatttga
    32221 aataatcaag aatattagaa acttctacat taatcaagaa ctttcttctg tatgaaaata
    32281 gagataataa ttgtacactt aagctgtatt caggaggtga agataatggg catcgaattt
    32341 agcgaacggc aaatgaaaat actatacttt ttgattgaaa atgagcacac aacttacaaa
    32401 gaattatcag aacaattata tgtatctacg aaaacaatta gcaaagatat tttaattttg
    32461 aaagaaataa tccaaaaaat gccagatgta caaatgttgg ttcaacctaa aaaaggcgtt
    32521 tcgcttattg gaaaaaaaga aacacttcga aatttattat ccagtcataa aatcaatatc
    32581 gcagactctc cggaggaccg tctaacttat gtgtttgcta aattattgaa tactaatgat
    32641 tctctaaaga ttcaaaatct tgctgacgaa ttatacgtga gcaggtcgac ggtagaaagc
    32701 acaatgaaag atgttagaaa aagactaaac aagcatggga tgtccttagt ttcagatcga
    32761 aatggcgtgc gcatcaaagc tgatgaaaaa agtaaaagaa ggttgatgtc agaagttgtg
    32821 aactattatt ggggtggctt tacagcatct aacagtaaaa cagatctctt agacttgaat
    32881 atcaatttca ttggtgaagc gaataatttc ttaaataagg acatattgaa aaaagtagcc
    32941 gaattgctta atcgatacat gaataagaca caattgaaat ttacagatta tgaatttcaa
    33001 actttagcta tccaccttgc tattgcgata gaaaggattg aaacaagcaa tttcttatca
    33061 cgtagtaata attctgaaga agaaatctca aagaatacac ttattttaat caaaatgatt
    33121 gaaaaagcat tttcaattat tgtgccaata gatgaacaag cttatgttga cattcacatt
    33181 acttcgattg aaaaaaatgc tatgaatcac gacttagatc aaacgaagct ttcctattta
    33241 gatatgggtg ttgagctaca agagttagta agaattaaat taaatgaatt ttatcctgat
    33301 gaagaattga tcaataatct agtattacat ctcaatgcag cagttaaaag actcaaattg
    33361 ggagtaaata tctataaccc ttatacggac aaaatcaaat attcttttaa aaggtcattt
    33421 atgataagtg tagatttatt agaggaaatc gaagagagat tctgtataca ttttaatgaa
    33481 gatgaaatcg cttacgtaac actccatatt caatcacttt tggatcgtta caaacctgac
    33541 aaaacgaaag tgatattagt ttgtagtagc ggatatggaa catcaaaatt attagagcaa
    33601 agaataaata acggttttgc agatatggtt gagatagaag atgtactaag catcaatgaa
    33661 ctacaagata gaaaagtcac tgatgaactt gttataagca cgattccgat tgaaaataca
    33721 aattttcctg ttattgttgt tagtcctttg atgttagggg cagatgtcag aaaagtaaaa
    33781 cagtatctac agttaaatga acaaacagaa gatgcttttc taaatttatt agataaacga
    33841 ttttgctttt ttacccacca aataaaggat aatcaagtga acgttttaaa tataattacc
    33901 aaaaaattgg taaaagaaaa ttacgcgaaa gaagggatac tagagggagc aatcaaaaga
    33961 gaaaaactat cttcaacagc gatgaatgat tttgctatgc cgcatatcga agtagatttt
    34021 ataaaaaagc cagtaatctg tgtctacgtt aatccagaag gaattgattg ggatgggaca
    34081 cttgttcatt ctgttttctt ttttgcactt aatgaaaaag taaaacctga attgaataaa
    34141 atttatgaaa cattcaatga aatcgcttcg aatcatgagt tattagcaaa tttaaaaacg
    34201 agttcgtcgt ttgaaaaatt agtttatata ttgaaagaag gcttataaat gatcagtgaa
    34261 aaaatcaata taaataatat agtgatagat ttaaatgcat ctgataaaaa aagtgtagtc
    34321 gaaaaattat cgaaattgtt agagactaat gggtttgtgt ctgaccacaa acaatttcaa
    34381 aaagacgtat ttgacagaga aaaccatatg accacaggaa ttgggaaaaa tatcgccatt
    34441 cctcatggca aaagcctagc agtaattgaa tcaacagtgg ctgtagccaa gttaaagcgg
    34501 tctgttgaat ggggcgcatt agatgatcaa ccagttgatc tcgtcttttt gttagcaata
    34561 aaagacactg ataaaggtac taatcattta cgtattttag cagaattatc tggaagattg
    34621 atggatgacg agtttgttaa aagaataaaa gattcgagaa ataaaaaaga attggtaaaa
    34681 gctctatcat tttaaaagga ggaatttcat atgacaaaaa tagtagcagt aacagcatgt
    34741 atcgcaggga ttgcccatac ttatatggca aaagctaatt tagaaaagtt tgcgaagaag
    34801 aaagggttag atattaaagt agaaacacag ggggctatgg ggatagaaaa caaactttca
    34861 atttcggatg tttccgaggc agatgttgtc atatttgcag tagatacaaa tgtttcagaa
    34921 cgaggtcgct ttgacggtaa accgatttta acagtaggga cctcagaggt agtaaaagat
    34981 ggtgaagaga cgattgatga agcaattgca ttaattaaca aataaaaaat atatcgtggg
    35041 ggagttacta atggaattca agaaacaagg aagagaaatt ctaaatcatt tccaaagtgg
    35101 ggtttcctat atgatcccgc ttgtcgtagc agcagggtta ctaacttcta ttgcagtcat
    35161 ttttggtggc acaggtgttt gggaccagac ggatacattc tggggagtcc tgcgaatgat
    35221 tggtcagacg ggattacagt ttatcgtacc gatgatttca gcctatatcg catattcaat
    35281 tgctgaccgt cccggtctag caccagcttt tatcactggg atgatgtgtc aaaatcttgg
    35341 tatgggattt attggaggaa tggttgctgg attagcttgt ggctatttag ctaatgcatt
    35401 gaaaaaagta aaagtaccga tgcaagttat tagtctaaaa tcaattatgc tgattccttt
    35461 tgttactaca ttagttgttg gaatcatatt atggtatgta ctagctacgc ctattcaagc
    35521 aatgacaaca ggactgacta attggctaga aggcatgtca ggagcaaatg ctgctttgat
    35581 gtcggctatt ttaggaggaa tgatggcgtt tgatatggga ggacctatca ataaaatcgc
    35641 atatgctttt ggggttgctt ctttttcaag cggaagcttt ggacctagta cagccatgtt
    35701 attaggaatt gctattccgc catttggaat gtttttagca acaattttaa acaaaaaact
    35761 ttatgatgaa tcggaacgag ataatgcaaa gacagctatg attatgggcc ttgtggggat
    35821 tactgaaggg acgatcccgt ttgccgtgaa agatccttta cgagtaatac caagcatcgt
    35881 ggtgggcact gcagtagcat gtggtctaaa tggatttttt ggtgttactc aagaaacaat
    35941 gctttcaacc tttatggcaa ttccttttgt tacgaatata cctttatatt tagtatcaat
    36001 tgttattggg ggagtggtta cagcgttaat ggtcaatgca ctaaaatcca tcaagtataa
    36061 aaaagaacaa caagtaaatt cagtagaaga aggaaagtag gagaatctga tatggtaaat
    36121 gcacatataa ttcaacacac gcactgggac agagaatggt attttacaaa tgaagatgcc
    36181 atcgtattgt ctgatcaggt ctttactgaa gttctagatg aattggaaag gaaccctaaa
    36241 gtaaactttt gtttagatgg acaaacttca atcgtcgatg agtatttgga gatcaatccg
    36301 caaaagctta aggttatcca acgactgatg aaaacaggac aactattcgt gggaccgtgg
    36361 tatgcacaaa cagatgcctt attagtggat gctgaatcaa ttttaagaaa cttaatgatt
    36421 ggaatcagtg atacgatcct taaatatgga gatccaatga tggtagggta tttgcctgac
    36481 acgtttgggt tcaatgcgaa tttgcctaca cttttgcatc aagtagaaat cgataatttc
    36541 atgtgttggc gaggattaaa ctttgaaacg atggttccat ctccttattt tatctggaaa
    36601 ggattgggag ataaatttgt ttatgccatg aattttccat ttggttatat gactggaatg
    36661 atgaccttag acgcaattaa agatattcct gaatttgcaa aagaaaagtt ggatgaagca
    36721 gttgaaatgc ttcatatgca aggaaaaaac aaagatattt tagtaccttc gggtgtagat
    36781 caaaagtcaa tgattttaaa ttttgatcaa gtcgtagaga agttgaataa atacagtaaa
    36841 ttccacaata ttatttcaga ttatccttct tatgtagaag ttatcagaaa caaaaaagaa
    36901 ttacctgaat ataaaggtga acttcgtcag ccggtttact ctcgtgttca tcgttctatt
    36961 ggctcagtaa gaacaaaaat gaaaatagaa aattttaaat tggaacaaaa aattctaaaa
    37021 cgagttgagc cgctcatgct gattgcagaa agaaatggta tccatatcag taaaggccta
    37081 cttcgtcggt tatggaaaaa gattttgcaa aaccaggctc atgatagtat tggtggctgt
    37141 gtttcagata atgttgcgga agatattttc catcgaatca aagaagctaa tgagatagct
    37201 gacggaatcg aaaaccttat tgtaaaacgg atggctgatg cattaaagct aaaatcgaat
    37261 gaagtccttg ttttcaacac aacgactgag aattatagtg gatcgaaaat cgtgcatgta
    37321 gtagctgatt caaagaaaat acacttcaaa ggtagtccct ataatatcat tgaaaaagaa
    37381 gtttattttc cagaacggaa aaatgcttat cggatgattg ctacaggttt cgaatatttt
    37441 gatgaaccag cttattatga acttgacata aaaataaatg taaatgtgcc agcactagga
    37501 tacactgttg ttgaatttga gaaaaataat gaaaaattag aaacagcaat cgagatagac
    37561 aaaactgaga taagtaacaa taaatataaa ctttctttta aagatgggca attgaatttg
    37621 atagttggag atagacaata tcttgatttc gttcatttga tcgattcagc aaatgatggc
    37681 gatacgtatg attattcacc attagaagga gatacagaac tatctctaaa attagaaaca
    37741 gctaaagtat ataaagattc tttacaagaa acattagttg tttacggaaa agctcaactt
    37801 cctaaagatt taaaagatcg tttatctgaa aaacccgaaa tggaagaaat atcttatgaa
    37861 atatcgttca gtctgggaga aagtcaaatc gttgaaggca cactcaaaat tcataatact
    37921 gtttactcgc atcgtatgcg cttagcaatt aatgttttag ataaatctga aaaatcaatt
    37981 gcacaaattc aaaacggatt tattgaaaat acccctgatg tcattcctcc gaattggtca
    38041 gaaactatgg tagagaaacc tgttaattta gaaatattcg ataagagtgt ctctgtggca
    38101 gaaaatgatc attattttac gttttatgca gatggtttaa aagagtatga acgtatagaa
    38161 aatcaattaa tcataacctt attttcaaca acaggggaac ttggaaaacc taatcttgct
    38221 tggcgacctg ggcgagcttc aggagatacg acaaatgaag ggcatgtcat gatggaaaca
    38281 ccgctagctc aagagatagg tgagtataaa gtcacttttg gatttaatgt agaagaagga
    38341 agatttaatg agttcaaagt ggcaaaacag gcagaaaaac ggttagaaca atctatttct
    38401 tatcaaaagc agaaactgaa tgtatttatt cacaggttag ataacaagat ttggccatta
    38461 caaaatgaac ttgatgttcc tcgtaaattt tcattgattg aattacctga agacttaatt
    38521 gtatcatcga tttatccttc ttattttcat gaacaaggat ttgttcttcg cttagctaat
    38581 ccaacagaac aagaaaaaat agtacctgag gctatccttt cccttgggac agttgtcaat
    38641 gcactggaga ataaacaaga attaacaaca attcctccct atgattattt gtcaattttg
    38701 ataaatgaga gataaatatg taatatacaa gaaaaaaaca ccttttattt tgaaaggtgt
    38761 ttttttaccc tcttttcaaa tagcgcaaca gtgctatact aaagctaaca aataaaggaa
    38821 cggagaggga tatgggtcaa agagaattta tcgttttaat tattattgca gctgttattt
    38881 tattagttgc tttagacatt ttttcacgtt tgaaattaaa ggaaacagtt cgtagcaaat
    38941 gggaaaaaat tccttatcaa ccgagatttg ataaagaaga aagcttgaag gaagcatggc
    39001 tcacggagaa gaagttccgt tcatgggata gcgaaatcga tgatcttact tggtatgacc
    39061 tggatatgtt cgaagtattc gaaggaatca acagtaccta ttctagtgta ggttcagaag
    39121 cgttgtatca acgtttacgc agctttgatt ttggtgaaga tcagcagtta gaaaaactga
    39181 ttgcttttta tcaggaaaat cctcaactga gagaaaaaat ccaatatcaa ttcgctcgtt
    39241 taggaaaaaa agatcataat tttgcaaaac aatatctagc ggatggaaaa agtaaaaaga
    39301 ttggacgcgt aggtttattt atttttcttg gcttgcttcc gctggtgggt ttgggtttgc
    39361 ttcttttagg acaagtacta ggaatctatt tggcaatcgg tgggttagta ttcaatacgg
    39421 tctattatct agtgaagaaa caaacactag aaacagagct gaatagcatg agttatttgg
    39481 tttcaacgat ttcagccgcc aatcagctag caaaactgcc gacaccactt caagaagagc
    39541 tgaaacagca aactaaacca ttaagagaca tccctaaatt aggtttttca tttcgtatga
    39601 agagtgggag tgaagcagag ttgatttttg aatatgtcaa catcatgttc atgctgccat
    39661 ttatctccta tcatttcgtt ctcactaaat tagaaaagca ttcaactgaa gccatcaagc
    39721 tgtgggaatt gctgggagaa ttagaagtag ccgctgcaat attgaattac cgtacttata
    39781 tgcccatcac ttgccgacca gagtttactg agggcggtgt gacagcgaaa gatatctatc
    39841 atccattgtt aaaagaagcg gtagtgaatc cggtcaactg gcagaagaat acattagtca
    39901 cgggttccaa tgcatcagga aaatctacgt atgtcaaaag tatagccatc agctgtattc
    39961 tagcacagac gatccaaaca gcgattgcag aacagtttac cctgcaacct ggacatgtgt
    40021 tgacttccat ggcaatcgaa gatgatttat ttgaaggcga cagttatttt gtttcagaaa
    40081 tcaaatcgat caaacgtttg ttggaccaag tggcttccaa agaacgctgc tactgcttcg
    40141 tagatgagat tttaaaaggg acaaatacga tcgaacggat tgcttcttcc gcttcagtcg
    40201 ttcggtggct tgcggagtat ccatctttag catttgtcgc cacacatgat atcgaattga
    40261 cagagatttt aaagaattat tgtgagaatg tccactttga agaacaagta acagaaggaa
    40321 aaggaatcag ttttgatttc aaattaaaag aaggaccttc aaggacccga aatgcgattg
    40381 ccttgctgaa agttttggat tacccagaga ctttagtaga aaccgcaaaa acggaagccg
    40441 cgttatttga tgaaaagcgg cagtggcatg tattgggata ggcgaagtga tcgaaagtat
    40501 ttattggatc aaaaatcttg gcttttgctt ccgccgttta tacgtgttta gagcgtgaga
    40561 caaaagtgtt ctttactttt gtctcacgct ccttttgttg cacatatgaa tagtaatcct
    40621 ttatcttcga tttgtttttt ctgaaaaggt tgtctgactt cgtccgattg atgtctttca
    40681 ttaggagatt ttcctgagcc cagcaacctg atttttcgct ggaaccaagt tgttttttca
    40741 tctgctgtat tccatgatac aataaagaat catgtctata aggagatagg aaataaatgg
    40801 caaatgcgct tgaaataaat aatttgaaaa aggtttatgg aagtggggtc gaagcattgc
    40861 gaggaatcga tctttccgtg aaagaaggag atttctatgc gctattagga ccaaatggag
    40921 ctgggaagtc tacaacgatc ggaatcatta cttctttagt caataaaaca tctggaaaag
    40981 tgaatgtctt cggttatgat ctggatacgg atctagtccg agcaaagcaa cagattggat
    41041 tagtcccgca agagttcaat ttcaatccct ttgaaacggt ccagcaaatc gtcgtgaatc
    41101 aagcaggcta ctacggtgtc tctcgcaaag aagcgatgaa acgcagcgaa aaatatttga
    41161 agcagtccaa tctttgggaa aagagaaatg tccgtgcacg tatgctttcc gggggaatga
    41221 agcgaagact gatgattgct agggcattga tgcatgaacc acgtttgctg atcttggatg
    41281 aaccaacagc aggagtcgat attgaattga gacgcgagat gtgggagttt ctccgagaat
    41341 tgaacgaaaa tggtacaacg atcattttga cgacgcatta tttagaagaa gctgaaatgc
    41401 tttgtcgcaa catcgggatc atccaatcag gtgaactgat cgagaatact agtatgaaag
    41461 agcttctatc caaactgcaa tttgaaacat ttatctttga tttagcgcca tatgagacca
    41521 aacctgtgat tgaaggatac gcttgtacat ttgaagatga acagacaatc gctgtcgaag
    41581 ttgaacgaaa tcaaggggtg aacggaatct tcgatcagct gacaagacaa ggaatcaaag
    41641 ttctttctat gaggaataag tcgaatcgtt tagaagaact gtttttgaaa atcacagaag
    41701 aaaataatca tacggaggag aaaaatgttt aatctttatt ttactgcatt aaaaagttta
    41761 gctatcaagg aaacgaaccg ctatttgcgt atctgggtcc aaacactggt tccgcctgtg
    41821 atcacgacat ccttgtactt tgttattttc ggaaaaatga tcggtggtcg gatcggtgac
    41881 atgggtggtt tttcatatat ggaattcatc gtgcctggtt tgattatgat gtctgctatc
    41941 actagttcgt atgccaacgt ttcttcgtcc ttcttctctc aaaaattcca gaaaaacatc
    42001 gaagaaatct tggtagcgcc tgttcctacg catgtgatca tttggggctt tgtgattggc
    42061 ggagtgggtc gcagtattct cgtcggctct ctcgtaacga tcatttcctt gttctttgta
    42121 ccacttcatg tgtattcatg gttcatggtc atcattacat tattgatgac ggcaatcttg
    42181 ttttcgttag caggactgct caacgggatt tttgctcagt cttatgacga tgtatcgatc
    42241 gtgcctacat ttgtcttgca gccgttaact tatctaggtg gcgttttcta tgccatctct
    42301 atgttgccgc cattttggca agctgtttcg aaagtcaatc cgatcgttta tatgatctcc
    42361 ggtttccgtt acggattcct tggaacaatc gatgtgccag tagcaacatc gatgatcgta
    42421 cttgtgctat tcatcgttgt tttgtacgcc gttacttggt atttgatcaa taaaggaaga
    42481 ggattgagaa gttagaaaag aggttgtgaa atcagcgttt tgacctgagt attagagaaa
    42541 caaacgggaa aatagttcct catattttgt cgtttgttga gctaataccg agggtcagct
    42601 gattgaacac cgtttagtgg agaggttgtg aaaaagctgt tctgcatcaa gtaataagaa
    42661 cagccaaaca aaaatagctc ctcctatttt tcgtttggtt ggacttatta ccgcagatgc
    42721 aagcttttga acaccattta ttccggaaaa ggaattgtga taagattttt gtcacagtct
    42781 ttttttgctc aatcagaaac atcttttaag ctgttcactt tgcttctttt tttgtttcct
    42841 agtataatga caatgttttt gagaaagatt gcgacttcac tgcttgatag aatggagagt
    42901 aacaaataaa tgactactaa tttttggaaa gagctgccaa agcctttttt tgttttagca
    42961 ccaatggaag atgtaacaga tgttgtattt cgccatgtcg taaagcatgc agcagcaccg
    43021 gatgtcttct ttactgagtt tacaaactca gacagtttct gtcatccaga tggaaaagac
    43081 agtgtacgag gaagattgac ctttacagaa gatgaacagc cgatggttgc ccatatttgg
    43141 ggagacaagc cagaattttt tagagaaatg agcattgcta tggcagaaat gggcttccaa
    43201 ggaatcgata tcaacatggg ctgcccagtc cctaatgtag cagaacgtgg aaaaggcagt
    43261 ggcttgatcc ttcgcccaga agtagcggca caattgattg aagcggctaa agctggcggt
    43321 ttgcctgtca gcgtcaagac gcgtatcggc tatacggaaa tgtctgagat ggaagaatgg
    43381 atcagtcacc tacttcatca agatatagcc aatctttctg tccatttgcg tacgcgtaaa
    43441 gagatgagta aagtagatgc acattgggaa gtcatcccta aaatcattgc tttacgtgac
    43501 caaatcgctc cgcaaacact gatcacgatc aacggagata tcccagatcg ccagacagga
    43561 gaagaattgg ccgaaaaata tggcgtagat ggcatcatga ttggccgggg gattttcaag
    43621 aatccttatg catttgaaaa agaaccgagg gaacatacag aaaaagaact gatcggacta
    43681 cttcgtctgc aactagatct gcaagatcat tattcagaaa tcatcccgcg ttccatcaca
    43741 ggactacatc gtttctttaa aatctatatc aaaggatttc caggagcaaa tgacttgcga
    43801 gttcagttga tgaatacgaa atctactgat gaagtacgag agatcttaga cacctttgaa
    43861 aaagaacatc caacgctttt cagtgaacaa tgatttcttg cttgaacacc gtgaattaga
    43921 ggtcgtgaaa aagctgtcct gcatcaagta ataagaacag ccaaacaaaa atagctcctc
    43981 atattttgtc gttttttgag cgaataccga gggtcagttg attgaacacc gtttaaaaga
    44041 ggttgtgaca aaagtcttgt cgcaacctct tttttaacca aaaaagtgca aatagtttac
    44101 tttaagtaag agaataatta tgatgaataa aagtggaaca aatagcatac tatatatatt
    44161 gaaatgaaaa ctgtatggat gctccaactt gatgaagcta aggaggaatt cgtatgtcag
    44221 aaaaggaatt aatgaaggta gtcggttttt atgaagggtt gtcgatcgat gatccaaaaa
    44281 gctttattga tgaaaaagaa cagatacctg tacccagttc acgggatctt ctggtaaaag
    44341 tcaacgcagt atctgttaat cctgtcgata cgaaacttcg ccaagataac gggataagaa
    44401 atgctttacg tatcttaggg tttgatggag tcgggaaagt tgttgctgta ggtgatgaag
    44461 tgcaaaaatt ttctgtcggc gatcgcgttt tttacgcagg tacaacgaca agagcaggaa
    44521 gcaatcaaga ataccaactg gttgacgaac gtattgtcgc tcttgcacca aaaaatcttt
    44581 cagatgaaga agccgcagcc ttgccgttga cctcattgac cgcttatgaa ttgttatttg
    44641 aaaaatttgg tctgactcca gaagaaaatg ccaaccgcgg gaaaaaaatc ttagtgatca
    44701 acggagctgg gggcgtcggt tcgattttga atcaactagc gcattgggct ggcctagaag
    44761 tctacgcgac tgcaagtccg aagaattttg aatggctgaa aaaaacaggt gtagactatc
    44821 caatcgatta tcatcacgac ttaagtaaaa gttttcgtga attaggaatc gatcaagtag
    44881 agtatgtcgc tgtattattc gatattaccc gctactttga tcaaatcaaa caccttgtcc
    44941 gaccatttgg acatgtggga acgatcgtag ggatcaaaga gccgttagat ataggtgttt
    45001 ggaaaaacca atctatcagc ttcgactggg agtatatgtt cgctaaaaca gactataact
    45061 atgaaatcga aacgcaagga gaagctttag cgcacattgc tgctttagca aatgaaggga
    45121 ttatccgcag tacattgagc aaggtctatt cagatgggat gaatgcgaag aacttgaaac
    45181 aagcaaccaa agacgtagaa acaggacata tattaggaaa agtcgttgtt agtggtccgt
    45241 tcaacggata agcaagaata cgccgatttt tttcttattt gactttgata aaaacaagag
    45301 cgcatgacag taatttgcca taagctcttg tttttttatt tataataagc gaatcaacga
    45361 aagggaaaga attcctacca agacgatcac caataagctt tttgaaagaa tagcagctaa
    45421 aagtgtagga actgaagcca aagcattttc gagattgatc tgcggcagat gtccgatatt
    45481 ttgggtaaat agactgctga accataaagc agacataatg acgatcggga caaaacttaa
    45541 atactcaagc aacggttgcg gcaaatcgaa ttttttcagt aagacaaatg gtaggatcct
    45601 agaaagccaa gttgctaaag tacaacctaa aatagtcagc aatgtaaact caaaagaagg
    45661 catgtttgat ccacaccccc aatccgcacc caatcagtgt tacaactaaa atcactaagt
    45721 tacttgggat aaaaatcagt ccgacatata ccagaatcaa agtgagacca atcaggatca
    45781 actgtaatcg tttagaggtg tttctatcag aaatgacttg aagataaagt aacccgataa
    45841 acatagcgac gatggcgaaa tccaaaccaa actttttcgg atcagtaata aaattcccta
    45901 aaagtgcgcc aacaagagaa gaacccaccc acgtcaaata agaaatccaa ttagctgtat
    45961 tcatccaacg aaagtttaac ttttgtccag tatagttcaa tttattcatt cccagtgcga
    46021 aactttcatc tgtcagcaat gtgccaatca gcagattttg aagcagccga tttttcttga
    46081 aataaggagc aatcgtcata ctcatcagaa tcattcggga attgactaga aaggtcgaga
    46141 gaacgatgga gagcagtgga ctatggctag caagcatgct gaccgtgata aattgggcag
    46201 aaccagcata gatcagcagg gacatcaacg tgacgaccag cggatgaaac ccggcagctt
    46261 tcccaacgat accaaatgca agtccaatac cgatataacc aaaaacggta ggtaacgtgt
    46321 ctttgatcgc agtttttata tctaactttt catccaataa caaaactcct ttagcacgac
    46381 ataaattttc ataattgtcg tcaaacttgt gaatattcta aatttttaat gaagacttgt
    46441 caacttcaat tttaaacaaa taaaaaagac tggacgtagt ttaaaaaaat cttctcaagt
    46501 tagatttcca gacctaactt ctgaggatca ctacatttgt cacagtctct tatactgaca
    46561 agtataaatg aagtatgaag aaaaagtatt tgttattggt atttctcatt attcttgttt
    46621 tctaatgtgt tcacttcaag tggaatttta gaatattatt caactaacaa gtctacatcg
    46681 tatctaaatc catttgtatc acttaattgc ttgtaaaatt cgccactttt tttaattgtt
    46741 cttttttgag tagtaaggtc gagtgaaacc agcccatatc ggtttttata ggcgttgatc
    46801 catgaccagc aatcaataaa tgtccaaaga tgatacccct taatgttaca tccttcattt
    46861 attgccttcc ataagtaagc aagatgatct ttgatatact caatccgata atcatcaatt
    46921 atttgccctg tatcatccat gaaacgttct tcatccgcaa cgcccattcc gttctccgag
    46981 ataaatgctt cgatgtttcc ataatggttc ttgatatcca tgcacaaatc ataaattcct
    47041 ttttcgtaaa tttcccatcc ccggtattcg ttcattcgtc gtccaggcat gatatgtggt
    47101 tcgaaaaacc actctggtaa aaatggacta gatgtatcca ccatagaaga acgagatttg
    47161 acgcgacgtg gctcgtaata gtttagtcca agaatttgag cggtattttc gtagatacat
    47221 acaagatctt ctttcgtata atcttcagga agctgattat attcttgtaa taacaggata
    47281 agctttttag aaaaattccc tttaaccata ggatctaaaa agctccgcgt ataaaataaa
    47341 tcagcgattt ctgctgcttt cacatcagca ggattttgac tacgaggaaa agtaggactc
    47401 aaatttagaa taacgcctat tttactagga agagctagtt ctttaaatac ttgtattgct
    47461 tttgcgtgtg caagtatagt gaagaatgct gcttgcgctc cgcgtttaaa gtcaatgagg
    47521 tttggataat gaaaatcttc aagataagta cctaaaatag gcccaagtgg ttcattgaag
    47581 gtaaaccaat gacaaactaa gtcaccaaat tctttaaaac aagtttcagc gtaatgaaca
    47641 taagcatcaa ctacttcacg tgattcccat cctcctttat cttgaagagt agcaggcatg
    47701 tcaaaatgat ataagttggc aaatactttg attccgttat tattcatttc ggaaaataat
    47761 tttcgataga aagaaatggc tttgggattt acttttccgg taccgccatt tggaaacatt
    47821 cgtgcccaag aaatagaaac gcgaaaggag ttatgcccag tttttttcat tagttctata
    47881 tcttctttat attgatggat gtgatcggtt gtaatagagg aatcgattcg ttgataaaac
    47941 cggtaaggtt gttctttaaa ccagcgatcc cagatagtct ctgcttttcc tgtttctcct
    48001 tttccttctg cttgctcagc tgaccaagcg gaaccccacc aaaaatcatc tggaaaagtt
    48061 agctttttca tagttgtcat aattttttta cctcctgttt ccacttaatg ataacaccgc
    48121 ttacaactta aagtaaatag ttttgtttaa atatatatat cttttttatt gtgtgtataa
    48181 ttttgatgtg gattttatcg gtttatttat gttaaagtat agatgaagat atgtttttga
    48241 ttggagggtc accattgaaa aaaattgcga agtatatgga aatttactta gatataaaga
    48301 aaaaaattgt aaatggagag tataaaattg gtgagaaact tcctacagga gatgaattgg
    48361 cagttattta tcatacaagc aagttaacag taaagaaagg cgtagactta cttgtttccg
    48421 aaggagtttt gcgaagtaga agtgggtatg ggactgaagt cgtcagaaca ccaattgata
    48481 actcacgagt tcttggtcca aacgaaggtt tgtttagcgt ggttggtgaa gaacacgtag
    48541 attcagaaat ccatactttc tcaattgaac ttccatcgaa aaaagtagct gataaattaa
    48601 gtatcagtgt aaaagactat gtatataata ttgtacgaag ccgttttatt gattgtcaac
    48661 catactcgat tgagcaaaca ttcatgccat tagcagtcat accaggcttg gaaccaaaac
    48721 atttaaagaa atctgtatat gcttatatca caaatgaact gggtctggaa ataaagactt
    48781 cgcacatacg tatcaaagga gatactgcga atgaatttga cgcaaaaata ttaaaaatag
    48841 atccaggtga atttatgatt gagatagaca aagttgttgc tctatcgtct ggtaaacctt
    48901 tcgagtattc ggtatcgaga catttatatc aagactttgt ttttgaagct gtttttgttg
    48961 aaaaataagc tcgggaaaat tattttttca gagcttattt ttttatacta aaaaagatat
    49021 atatatttaa ttaaaagtat ttactttttt tgataagtga tgtattattt gggtggaaaa
    49081 agtaatcgat tacaataagc ataaaggaga aaaaatatgg gcaaaagtag caggaaggac
    49141 attgtatttg aaaaatttgg tatagttgcg actaagttgg ggaatcagat ccatttaaga
    49201 actttgcgag atgcgtttgc tacatttatg ccatttatga tgttagcagg atttgtgaca
    49261 cttattaatt cagtgatctt agaaccaaca ggattcatgg gggaaattgt cgatactagt
    49321 acattgacca cgttacaaca aattggtact tcaattgcca atggtacatt aagcataact
    49381 acattattag ttgtagcagc agtatcttat catatgtgtg caagcagaaa ttatacaaat
    49441 catattgcag cggtattagt tgctatttcg acatttgttg tattaacacc tatgcagatg
    49501 atgtttactc ctgaaaatgc ggataaagct gttgaagtga cgggtgtgat acctatatcc
    49561 tatacaggag cttcaggaat gtttgtaggt atatttgttg gattagcggc tacagaatta
    49621 tttattaaac tttctaataa taagaaacta cagattcagc tatccggaaa tattcctccc
    49681 gctgttttaa agtcttttaa tgtattaatc ccaatcatta ttacgattac ctcgtttgct
    49741 ttattgtcat ttataatcat tcaattgttt aatatggata taaataagct aattaccacg
    49801 atagttacag agccattaag taaaattaca actggtttac caggattttt gttaattaca
    49861 tctattgcta atctattttt tggatttggt atccatcaag cagtaatatc aggttcattg
    49921 ttagatccgt ttttgattca gaatatgcaa gaaaatatgg cagcttatgc aaacaaagag
    49981 caaattccac atattatcaa tatggccttt aaagatacct ttgcggtaat gggtggatcg
    50041 ggaaatacga ttgctttatt gattgcaata tttatcttca gtcgtagaaa agattataag
    50101 gactttgcta aattatcggt aactcccgct atattcaata taagcgaacc tattattttt
    50161 ggattgccta ttgtatttaa tatcagtctg attattccct ttgtgcttgc accgattttt
    50221 tctttgacag tagcatattt tgcaactgct gtgggattaa ttaatcatgt agtagtgcaa
    50281 attccttgga ctacgccacc agttatatcg ggatttttag caacagccgg agactggcga
    50341 gcagctgttt tacaaatatt aattatagcc gcaagtgtgt ttatatattt accgttttta
    50401 cgaattgacg aacacgtgac aactaaatta agtgaaaatg aaacataatt tactatgaga
    50461 taacaaaaat taacacaaga agtcgttgga atataaatag ccagtaattt caataaggat
    50521 catatttttt gataagtacg aacatgtaga aaaacaaaca ttttttggta aggataatca
    50581 ttatttttca caagacaaac ctatctgtgt atatacgtct atttagtata tgcaaagata
    50641 ggtttttggt ggtgaaaaat aaagactgtt aatattatta atcgttattt taatatttat
    50701 ctttaaagat tagagtggtt cgacacacct gaaagttgtt gtcagaattt tatccaatat
    50761 acagatgcag tggaacctct cttacaaaat gtagaaaagt atcataaaat ctatcaacaa
    50821 tgccggaaaa tctacccagc aacgaaggaa atttgtcatg acttataaaa caaaacgcgt
    50881 acctaatagt caaatgacta atattgggta cgcgttaagt cttctttact tcatcctttg
    50941 catgattcgt gtttttaaag caaggtctgc tgtatttctt gtggatttag gatggttgtt
    51001 atcgtttact tgctattttt cattgaaatc gtctttcttt accgtttctt tagttttttt
    51061 atctattttt ttcttttggt tagaaaattc tttttcccga aagtcttctt tcaggatttt
    51121 tatggagtag cgttttgaat aagaggcgtc agtatgatcg acttggcaga cgaaccaaga
    51181 gaacatttgc cttttttctg catgaggtgc ttctgctaat aattctttcc ataaataata
    51241 acagtcctct atcagaagaa gggttcgttc atcctcaggc tcccaataga atgtttcgag
    51301 agtagcaatc acttcattga tcaattcgaa tgcgggaaga taggcatttt gctgaatgag
    51361 cgattcaact gcttcttgga tgaactttcg catctccatg atgaacttcg ctgttttcct
    51421 gtttttgttt ttcttgataa tatgatcgta tttatggatg atagttgtta atttatctga
    51481 ataatttatt gcatgaaatg gcatcttaac tttgaagcgt tcgataaatt gcggatgttc
    51541 tataagaatc tctgttaaaa gctcccgtac aagagaggaa ctagcggagg aaacaaggga
    51601 cgagagttcg gaaagtgagt agttggattt ttttattgga cgttcttcgt aagcgaataa
    51661 gacagcagcc atgtgtttgc atttttttcc ttctatggca tatagacaat cacaagtcat
    51721 gttggtcttt tcatcccaag tgatcactac cttataatct tccgtgccag aaactgttgc
    51781 ggacaagtac ttgcttgtat agttcaaatg acggacaaaa ccgtgcagat gatagctgta
    51841 accgcgttcc aaaacgtttt caggaaaata ctcaagccaa ttattcatct ag
//
LOCUS       DAZAOD010000012        46063 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000012 DAZAOD010000000
VERSION     DAZAOD010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.012"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(62..724)
                     /locus_tag="ACHDPO_000747"
     CDS             complement(62..724)
                     /locus_tag="ACHDPO_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3368395.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            908..2554
                     /locus_tag="ACHDPO_000748"
     CDS             908..2554
                     /locus_tag="ACHDPO_000748"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFN3368396.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            2545..3627
                     /gene="uxuA"
                     /locus_tag="ACHDPO_000749"
     CDS             2545..3627
                     /gene="uxuA"
                     /locus_tag="ACHDPO_000749"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFN3368397.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(3735..5288)
                     /locus_tag="ACHDPO_000750"
                     /pseudo
     CDS             complement(3735..5288)
                     /locus_tag="ACHDPO_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            5436..6577
                     /locus_tag="ACHDPO_000751"
                     /pseudo
     CDS             5436..6577
                     /locus_tag="ACHDPO_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(6703..7782)
                     /locus_tag="ACHDPO_000752"
     CDS             complement(6703..7782)
                     /locus_tag="ACHDPO_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFN3368398.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(7885..8325)
                     /locus_tag="ACHDPO_000753"
     CDS             complement(7885..8325)
                     /locus_tag="ACHDPO_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFN3368399.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(8382..8792)
                     /locus_tag="ACHDPO_000754"
     CDS             complement(8382..8792)
                     /locus_tag="ACHDPO_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFN3368400.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(8972..9406)
                     /locus_tag="ACHDPO_000755"
     CDS             complement(8972..9406)
                     /locus_tag="ACHDPO_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFN3368401.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(9506..10354)
                     /locus_tag="ACHDPO_000756"
     CDS             complement(9506..10354)
                     /locus_tag="ACHDPO_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFN3368402.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            10743..12509
                     /locus_tag="ACHDPO_000757"
     CDS             10743..12509
                     /locus_tag="ACHDPO_000757"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFN3368403.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            12611..13870
                     /locus_tag="ACHDPO_000758"
     CDS             12611..13870
                     /locus_tag="ACHDPO_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFN3368404.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            14017..15318
                     /locus_tag="ACHDPO_000759"
     CDS             14017..15318
                     /locus_tag="ACHDPO_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3368405.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            15321..16172
                     /locus_tag="ACHDPO_000760"
     CDS             15321..16172
                     /locus_tag="ACHDPO_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFN3368406.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            16185..17000
                     /locus_tag="ACHDPO_000761"
     CDS             16185..17000
                     /locus_tag="ACHDPO_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFN3368407.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            17151..18317
                     /locus_tag="ACHDPO_000762"
     CDS             17151..18317
                     /locus_tag="ACHDPO_000762"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFN3368408.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            18547..19194
                     /locus_tag="ACHDPO_000763"
     CDS             18547..19194
                     /locus_tag="ACHDPO_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFN3368409.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            19278..20222
                     /locus_tag="ACHDPO_000764"
     CDS             19278..20222
                     /locus_tag="ACHDPO_000764"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFN3368410.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            20357..21808
                     /locus_tag="ACHDPO_000765"
     CDS             20357..21808
                     /locus_tag="ACHDPO_000765"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFN3368411.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            21829..22665
                     /locus_tag="ACHDPO_000766"
     CDS             21829..22665
                     /locus_tag="ACHDPO_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFN3368412.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            22665..23324
                     /locus_tag="ACHDPO_000767"
     CDS             22665..23324
                     /locus_tag="ACHDPO_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFN3368413.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            23450..24139
                     /locus_tag="ACHDPO_000768"
     CDS             23450..24139
                     /locus_tag="ACHDPO_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368414.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            24145..25101
                     /locus_tag="ACHDPO_000769"
     CDS             24145..25101
                     /locus_tag="ACHDPO_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFN3368415.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            25145..25657
                     /locus_tag="ACHDPO_000770"
     CDS             25145..25657
                     /locus_tag="ACHDPO_000770"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368416.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(25913..26461)
                     /locus_tag="ACHDPO_000771"
     CDS             complement(25913..26461)
                     /locus_tag="ACHDPO_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFN3368417.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(26550..27731)
                     /locus_tag="ACHDPO_000772"
     CDS             complement(26550..27731)
                     /locus_tag="ACHDPO_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFN3368418.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(27967..29475)
                     /locus_tag="ACHDPO_000773"
     CDS             complement(27967..29475)
                     /locus_tag="ACHDPO_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFN3368419.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            29634..29825
                     /locus_tag="ACHDPO_000774"
     CDS             29634..29825
                     /locus_tag="ACHDPO_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368420.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            30028..30945
                     /locus_tag="ACHDPO_000775"
     CDS             30028..30945
                     /locus_tag="ACHDPO_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFN3368421.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            30938..32011
                     /locus_tag="ACHDPO_000776"
     CDS             30938..32011
                     /locus_tag="ACHDPO_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368422.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            32159..32677
                     /locus_tag="ACHDPO_000777"
     CDS             32159..32677
                     /locus_tag="ACHDPO_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368423.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            32658..33050
                     /locus_tag="ACHDPO_000778"
     CDS             32658..33050
                     /locus_tag="ACHDPO_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFN3368424.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            33126..34061
                     /locus_tag="ACHDPO_000779"
     CDS             33126..34061
                     /locus_tag="ACHDPO_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFN3368425.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            34194..34973
                     /locus_tag="ACHDPO_000780"
     CDS             34194..34973
                     /locus_tag="ACHDPO_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFN3368426.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            34966..35283
                     /locus_tag="ACHDPO_000781"
     CDS             34966..35283
                     /locus_tag="ACHDPO_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFN3368427.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            35527..37137
                     /locus_tag="ACHDPO_000782"
     CDS             35527..37137
                     /locus_tag="ACHDPO_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFN3368428.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            37294..38142
                     /locus_tag="ACHDPO_000783"
     CDS             37294..38142
                     /locus_tag="ACHDPO_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFN3368429.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            38373..38852
                     /locus_tag="ACHDPO_000784"
     CDS             38373..38852
                     /locus_tag="ACHDPO_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFN3368430.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            38885..41113
                     /locus_tag="ACHDPO_000785"
     CDS             38885..41113
                     /locus_tag="ACHDPO_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3368431.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGHPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            41242..42885
                     /locus_tag="ACHDPO_000786"
     CDS             41242..42885
                     /locus_tag="ACHDPO_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFN3368432.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(42958..43503)
                     /locus_tag="ACHDPO_000787"
     CDS             complement(42958..43503)
                     /locus_tag="ACHDPO_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFN3368433.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(43526..44011)
                     /locus_tag="ACHDPO_000788"
     CDS             complement(43526..44011)
                     /locus_tag="ACHDPO_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFN3368434.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(44001..44813)
                     /locus_tag="ACHDPO_000789"
     CDS             complement(44001..44813)
                     /locus_tag="ACHDPO_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFN3368435.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(44952..>46063)
                     /locus_tag="ACHDPO_000790"
     CDS             complement(44952..>46063)
                     /locus_tag="ACHDPO_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFN3368436.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        15250 a         8291 c         8980 g        13542 t
ORIGIN      
        1 taataaagat tactcaaaaa cgaaggttaa ttataaaaat agaagaggtc gcaagaaaat
       61 gctactgctg gaaatactcg ggataacgtt gagtaacagt ttcctgttct ttcagcatca
      121 tgtgtaagtg caatcccgtt tgaaatcgag cttcttctgg ttttttatca actaaagcct
      181 tgagtaaatc ataatgttgt tccatgatcg tttcccatgg aagcccctga atggtcactc
      241 gtaaccagcg gaaacgttct aaatgggtat tatggtcatc taaccagttc caaacttctt
      301 ttcttcctgc aatttcgaaa caagcttcat gaaataaatt atctgcacgg aaaaaagcgc
      361 gttcgtcatt tattttgact gctttttctt gttcttctaa aatcgtttct agcactattc
      421 gtgtttgtgt gtccaatttg gaacaacatt caatcatgat ttgctcttcc aactgttctc
      481 ggacaaagcg agcattttct gcagaaacaa gattaatttt ggaaacatac gtaccacttt
      541 gaggtatcgt atacacgagt tcttgctgac gtagttgaat caatgcttcg cgaatgggag
      601 tccggccgat agcaagatgt tcctccagtg ccttttcaga tattttcctt ccaggttcta
      661 agtcagcata gataatttgt ttacgaatcg cttgataagc ttgtgattgc aagctgcttt
      721 tcatctttat tcctccaaaa tcatttctat gaacgtagta taacagaaga ggtctgaaaa
      781 acaatctggt atgtcacatt aactagtaaa tttgtataaa tagtaaaatt ttggttgaca
      841 tagcgatttt tattgcataa aattcacttg aatacaaaaa ctaatatgtt agtttaggag
      901 gggaaaaatg attgatttaa acaactggag gaactttatc cctgaattat ctcaaaaaga
      961 agtagaaata cctcattttg accgtgcatc attaagagaa aatggacaaa aaaatcctgt
     1021 ctggatccat ttcggtggcg gaaatcttta tcgaggattt catgcagaaa tcgctcaacg
     1081 tttagcggat ctaggcgaat tgtccactgg tgtcattgtt tgtgaaacat tcgatgaaga
     1141 aataattgaa agggcttacc aagattttga tgatttgatt cttgaagtgg tcatgccaag
     1201 cagtggagag ttcgtcaaac gtatattagc tgcgacagct gacagtctgt attgtcatcc
     1261 agattgttct gaacactttg ataagatgat tcgacacttt gaaaatccta gtttacaatt
     1321 agttactttt gctattactg aaaaaggtta tcgattgaaa gatacaaata ataaatatat
     1381 aggaccgatt gcagtcgata taaaaaatgg tccaaagaag ccatcacata caatgagtat
     1441 tcttgctgtg ctactttata aacgtttttt atctggagct tggccgattg cacttgtctc
     1501 tacagataat ttttcacaaa acggtagtca attacgtact tctttgctaa cgatcgcaaa
     1561 agaatggcaa aaggaaggtt atgtacaaaa tacatttatc caatacttat cgaatgaaga
     1621 aattgttgcg tttccatgga cgatgattga tcgtatcacc ccgaatcctt ccttgtcagt
     1681 tagcaaaatg ttggcaaaag agggcttttc aaatatgtcg attttccaaa ccgcaaaagg
     1741 aaataatatt gctccatttg tcaatacaga ggacatccat tatttaatca tggaagatca
     1801 ttttcccaat ggacgtccga aattcgaaaa agctggggta ttcttgactg atcgtgcaac
     1861 ggtagataaa gcagatacga tgaaggtgac gacttgcctt aatcctttgc atacgtcttt
     1921 agctattatg ggttgtttac tggggtatag gagcatagct gaggagatga aagatccaga
     1981 tttatcgctg ctagtttctg aaatcgggta caatgaaggc ctcccagttg tggagtctcc
     2041 aggtatcatt gatccaaaga tctttctgga agaagtaatt actgtgcgct tttctaatcc
     2101 aaatattcct aatatgcctc agcgaatcgc cacggatacc tctcaaaagg tggcgattcg
     2161 ttatggtgag acgattaaaa aatatatgga aatagaagtt aaagacccgc agacacttgt
     2221 attcatacca ttgactctcg ctgcttggct tcgatacctt attggcattg atgatcaagg
     2281 aaaaccattc atcccgagtc cagacccact attgacagac cttcagcata agctttccga
     2341 tattcaactg ggtacgcaag atacatcaca tattcatgag aaaatggctc ctattttgtc
     2401 aaataaagaa atttttggtg tagatcttta ccaagcagag cttggcagaa aaatagaaga
     2461 aatgttcatc aagatggtag caggaccaaa tgccgtacga aaaacattac aggattactt
     2521 acaagaacat ggaggaaatt tatcatggaa atgactttta gatggtacgg atcacaggaa
     2581 gaaaagatta ccttagatga aatcagacag attcctgcgg tcaaagggat tgtaggcaca
     2641 ttgatggata taccagtagg agaggtatgg cctagggaga ggatcaaaga actaaaagaa
     2701 gaaattgagt ctcgtgggtt aacactaaaa gtaattgaaa gcgtcaatgt gcatgatgcc
     2761 attaaaattg gattaccttc ccgtgagcag tatatcgaaa actataagca gacaatccga
     2821 aacttggcag aatatggaat agaagtcatc tgctataatt ttatgcctgt atttgactgg
     2881 gtgaaatctg accttgacta ccgcttagaa gacggctcat ccacgttagc ttttatatct
     2941 gatgatattc cagatgatcc aagagaaatc gtcgcgcgca tcgaacattc cagcaatgaa
     3001 tttggattgc cgggatggga acctgagcgc ttagctccta tcaaatcctt gcttgaagcc
     3061 tatgcatcag tagacgaaga aaaacttcga gaaaattttg cctattttct ccaatcaatc
     3121 atcccaacat gtgaagaggt aggggtcaaa atggctgtac atccagatga tccgccatac
     3181 tcgatttttg gattagctcg aatcgtaaag aatcgagaag atttagattg gttgtgtcgc
     3241 atagtagaca gcccttataa cggaatcact ctttgtacag ggagtattgc agaagatcca
     3301 gaaaatgatg tatatgggat tttagcagaa ttttgccaaa gagatcgaat cccatttgca
     3361 catgttcgaa atattaaatt tttagctaat cgagatttct atgaggcacc acataaatcc
     3421 gaatacggtt cattagacat gtaccgcata ctaaaaacaa tgtatgacaa cggatttaac
     3481 ggatacatcc gtcctgatca tggaagaatg atctggaatg agacaggaag accaggatac
     3541 ggcttatatg atcgagcatt aggtgctgtt tatctaaatg gattatggga agcaatcgaa
     3601 aaaggaaaca aaagtaaaga taattagtga aaaaaactgt aattttatta tgtaaataag
     3661 aaggatgttc aaattcttga tacataaatc cggaggttgt taataagcat tcggatttat
     3721 gtatcttatt tggtctagga agtaacttga ttttcttttt tcgattgatc catgagtgct
     3781 tcttctttta attcaaagat atattctgag atcctcataa tcactttttt ccagtcttct
     3841 ggtgtgatga ttccttttaa aatatagatt tttttgatat gagaaggcaa ttgtttcaaa
     3901 gggcagtcgc tgataacgat gttgcagttc tccataaaat cattttgtat tttgatcgat
     3961 tcatttgaaa aaatttgttc tatcttaacg atcagatctt tactgatata aaaatcacgc
     4021 gtatagttca caccaatcac aattcgcggc tgttttttgt agcgatcata caaatgtact
     4081 aggtcttcaa ccatccattg cacattttcc ttttctaaaa taactggtaa caagtgttga
     4141 ttttgttctc tgaaatccat ataaaattgt tcaatggcgg tttggacttc tttcaatacg
     4201 ctatgttctt gataaagcat gaaagtagga aggggcgtat ttggttgatt gaagttaaga
     4261 aatccattat aaagtttatt tcgtgcgaat gccaatgagt aaagaatctt ttctttttca
     4321 ggtataaaca aatcaaatac agtacaaagg gactccacca tttctcttga ataaagaaca
     4381 tgaggaacgt ttgctttttt taaaagtttg tattgctcca agcttgtttc ttccgattcg
     4441 attttcgtga tagaaagtcg agctaaaata ttcactaaga tgcgttgttc gcgacaaatt
     4501 ggcagattag gtcgcaaaat atctacagag agatcaataa aaaagtcaat atattcatac
     4561 tctgtgaatt ctttttgtac gtctttcaca gaagttgcag gaaaattctc tttacatatt
     4621 tttaatagaa aatataattt atctatcata ccgctattta gtcggtcaag tacttctttt
     4681 ttaaaaaaag tattcatcat aaaagccact acttgcggat cttcatcata aaattctgta
     4741 gcagtacttg aaaagatgtt ccaataaata tctaatgctg catattgaat ttgtacctct
     4801 tttccagaaa aagactttct gccattatta gaaaaggaga tagacaaacc gtactatgct
     4861 aaaaatgcat taatcttttt cattttcgta tacaaataag aggcactata gtttgtttgc
     4921 tgactgaaac tgataatcga atttgtctga cagctgaaca aagaagtcaa gatctgataa
     4981 ctgactgatt cgttgcagta tcttccaaat agacgataat agcagtaagc cggatcaatt
     5041 ccttcaaaat tcaactttaa aaaaggtttt tgcttatcaa tatgcagttc tgttagattg
     5101 agacgctcaa agtcttgttc taattctttg atgtatagta aaaaatttga ttcagacata
     5161 tggaaatgat ctgctaaata ttgtgtagta ataaagaaac gatgttcaga taggaaaaga
     5221 aaaatatcta attttgtatt gctttttttc ttcaagataa acgttttaat cgcttcttga
     5281 gtttgcatga aagaggctcc tttttactta aattgttaaa acttgaaaat attactgttt
     5341 ttttcataaa tttagacaaa aaaacagtaa acatataggt agaatctcta ctatcttatt
     5401 tcttgcatac aaaaaaatca aggagtgaga gagttatgag atattcaacc atcttaatat
     5461 caacatttgc agccttaagc ttatcgctta ctataaatca gacagtccac acagaggaga
     5521 cagaaacagc caaatggaca gaaaccaagt gggccaacgt caatcgaatt acctttcagg
     5581 atgaattttc atccttcaat tcaggagtcg caaaattaag aaaaggacaa acagcgacca
     5641 tcaaagcaaa aattgactat tcgggagact tagcacctat actacaatca gctgttacat
     5701 ttgagaatgt tgatcccact ttgtcgattg gctatgacga gaacactttg actatccaac
     5761 acaagcaagc gatatttacc ttcaccgtta cattaaatca ggacttgtta aaaccagcgc
     5821 tttttactgt caaggtatca gatggactac cgaacgatca tcatttaacg ccgtatagtc
     5881 agcggcagac aattgagcaa gattcagcca tcgactcagg aggagatctt gttgaagaac
     5941 caacagataa accagaaaat gaaaataagc cagaagtacc gcctacagaa aatccagacg
     6001 gagaacagaa accggaaata gaacctggag aagaacccga tacagaaact caaccagagc
     6061 cagacaataa atcaaaacct gaaataaccc ctggagaaaa accagatgta actccagaac
     6121 cagatacgga ttctggaaac caaacagtac cggaaacaaa tccagacaca gataatgaaa
     6181 ctgaaaatcc agaaaaacca gaggtagatc cagaagaaaa accagatgtg actccagaac
     6241 cagatacgga cgcaagagac caaggaatac cagaaaaaat aaacaaaaaa acaattcaag
     6301 aggatggaaa aaaagagagt aaaaaatcaa atctagcaat tctaaaaata aatgaagagc
     6361 agctgaataa aaaatcacga atatttgata gcgcccaatc agctgaaacc ttaaaaagta
     6421 gcaaggatac aacctttgct gtcctgaaac gaaaaataaa cagctaccaa aatccggaga
     6481 gtcacaaaac aaagttatac tgtggagcgg aatcattcta ttaagtatag caacaatgct
     6541 ttctgcaaaa agatttaaac aaaacagatc tctctaacat ttgaataatg tctgtgaacg
     6601 catttttcaa ataaaaagaa atatccagaa aatgacccca aaataccaga ttgaaatctg
     6661 atatttgggg tcgttcatac tttatctttc ttcatattta ttttaaggga tatctgtttc
     6721 ttttggaaga tggttcggga tctttttcac tttcaataca tctaaaaaga aggtaaagat
     6781 cggaatgccg acaatcaagc cccaaacgcc aaagaaccgt tcgctaacaa gtaagaccac
     6841 aaatgtataa aaaatcggca gttctgtttt gctggacatc aacttcggat tcagcacata
     6901 agactcaatt agatggacaa tcaaaatcgt aatcaggata taaacaacat ctcggatgcc
     6961 tccttgggaa taagctatga aagatagagg aatacaagaa atgataacac ctgctactgg
     7021 gatcagactt aaaatgaaaa tcatgatcgc taaactcagc agctgatgaa agccaaatac
     7081 agccaaggcg attgtagtga gcaacgtatt taaaagagcg acaacaaatt gagcttctaa
     7141 taccaaacca aatgtattga caaacttatc ggcaaaatag taaatatctt gaaagaacca
     7201 agaaaattca ctttttaaaa acaatcttga gaatacaatt gtttttttct tttcaatcat
     7261 aaaaaagaaa cttaagatga atgacatagc aaacgccact gccatttttc ctatatcctg
     7321 taaatagcca agcgcaatcg aagcgccatt ttgaagctgt tcaaaaaaat cgtttcgctc
     7381 aatataagta tggatatatt gtaaaacagg atctgcatct tttggctgat gctcgtaaaa
     7441 attaataacg gactggatca tgtcaaatgt ttgatgaata agcatcggga tatactttgt
     7501 gaatgccaga tagataaggt aaacgatcag tgtataaatc atgatagcta aaacacctgt
     7561 agggattcgg acaaatcgct gaatgatttg aacaagatga atcatcaaat aagtaaagat
     7621 aaatgtgagc aaaatggttg taatcatact tctaactaag aaaagaacaa aaacgacaaa
     7681 taataaaaca gtgagacggc gtattttttc attcgccaaa aaacgctgat aaacggtcaa
     7741 atcgacaacc tccaaataac aaaaaataaa cacgttattc attatatgat ggaatatgaa
     7801 aataagaaag agcaaaaaga aaaaccgcta aatgacgtta tcttatgagt tggttttcct
     7861 cataaaatcg ttcatctagc agtttcagcc ctttttctgg tcttgatgaa aattatctag
     7921 catttttcgg gtcagatgtt gcagtgtatc caattcttcc tgttcaagtg gaagataaga
     7981 cttgatcttt tgtggaatac cttctgcttg tttttgcaac gcagcacctt gagcagtcag
     8041 cgtaacattt acgattcttt catcacccgt ttcacgctga cgattaatat aatttttttc
     8101 tgctaacttt tttagtaagg gagtcagcgt accagaatcc agacacaaat catttcctag
     8161 ctctttcact gaagtctttt tcttttccca taaaactaac atcacaagat actgggtata
     8221 ggtaagattc agcggcttga ggaggggagt gtagtgtcta atgatttctt tagaggcggc
     8281 atataaagga aaacatactt gattaactaa atatagatct tccatttttc cacctccgct
     8341 gttttactat agtgtatcat agcggattta cacaaaaaag tctattcact aactgctttc
     8401 agagtaactt ctatatttcc agctgtagct tttgaatacg gacacacttt atgcgctgcc
     8461 tctaataatt cttgcgtttc ttccagagaa agaccttcga tagatccttc aatctctaca
     8521 cctaagacaa agctcgtttc actttctgaa taaagggaaa cttgtgcact gacagtagaa
     8581 gccccagaga tatttttttg ctgtttgatc aattctaatg cactgttaaa acatgcactg
     8641 aaaccagctg caaacaattg ttcagggttg gttgcatttt cgacgcgttt accaggagct
     8701 gcaatattca attcgaatgt acgatcggga ttatgcactt ctccagagcg tccgcctgtg
     8761 ttgatcattt tcgtagaata catttttttc ataaagttac cacctttaat tatattttat
     8821 acaattgaat tttacacaat ataattgtgg aaagcaaaga aatggattgg cataagataa
     8881 ataagagaaa gcacatgaaa cagacgcgct ttctcgaata gcaaacatat acaaaaaata
     8941 tcagagacaa aaaataatct catcataaac attacatata tttctcaaaa agttgttttc
     9001 tttcttcaaa aattacttca cgatggacct gatgaagcat ccataaataa ccaaaaggat
     9061 ctctgaacat tgagttagtc acaccaaagt ccatcatttc tgtcatttct tgaatctcta
     9121 cacagccatt tcgtaatgct ttattatgtg tgtcctcgat atcagagacg atgatattga
     9181 accagatcgt atttggatgt tcagcagtag gagcagtcaa accaagagac gtgttttcat
     9241 ccagcatatg gaatctcgta ccatacaagg taaaaatgac ttcattattg cctctagggt
     9301 aatctgttgc ctcaatcagt tgtatttcat caaagattgt ttgatacagt tctagtgctt
     9361 tcaaactatc atttaataca aaatcgattt ccgttccttt atgcataaag atctcctctc
     9421 cttttcagtc gaacagttac tagattcttt tattatacca gctaaagaaa acgcattcaa
     9481 aaaaatagcg gatttactta ccaactcatt cgattggatg ataagtaaat ccgcgtccca
     9541 ttacttctgc tacgctgctg acaatgacaa aggcacttgg atcgatttct tctatcaatg
     9601 gtttcattcg ggaaaattca tgatcagtca caacgatcaa taaaacctct tttgactttc
     9661 gattataccc gccttttgcc tctagcaggg taaggccacg tccaatctca gcacttaagc
     9721 gaaggcggat gtcttccaaa taatgttcac tcatgaccat aacagatttc tttcgattga
     9781 tacctgtttc gatataagtc atgacaattg aagtgattgc aatagataaa atagcataaa
     9841 gaaactcttc tattccaaaa ataaacagat taagagaaac aacgaatgcg tctgtaaaaa
     9901 ataagccaat cgaagtattc aagtggaaat attttttaaa aatgagggga gggatcgtcg
     9961 taccgccgct agaagagttg tttttatata aaatcgcaac tcctaaagca aaaatcgcac
    10021 ttccaaaaat gacagacaac aaccgatctg aagtaatcat tgtttctgga actattgcaa
    10081 tgattaaagg aaaaaccaag cttccgaaaa gtactttaaa aaagggtttt ttacctaaaa
    10141 atagaagagc tagtaccaac ataacgatat tcaacactaa aataactata gctcggtcaa
    10201 agcctaaagc agcttccagt aatattccta gaccgctgac acctccagca gcaatatgat
    10261 gaggccctaa aaacatattg atagcgactc ctaatatgaa gagggcaaaa ataatcttaa
    10321 tgtatgtcca tataaattgt ctcgtttctt tcatttattc acttccttaa ttcattaata
    10381 atactcttat cttattataa cttacttttc accttaagtt aactttaatt aataaaaaaa
    10441 ttaggctagt ctaaattatt atgtttcatt cttctagaat atacttctac gccaaaaact
    10501 gttaaaaaac ttttacttta gaaaattgga gaaattgatc gcttaagata aattcaggac
    10561 actaaatagt acaggaagta gactaaaact tttaaaagtt ttaagtctat ctatttggca
    10621 agtttaaaaa ataaaaattc ggtatcaaaa aactgttacc gataacattt ttgaaagcgt
    10681 tgtcttttgc ttctctatca cttatagtga tgacgtcata ttaaaacaca aggaggaaat
    10741 caatggatac agctgcaatt tatcatcgac cggaaagtga atatgcattt ctatatacga
    10801 atacaagatt tcgtattcgg cttcgtacta ggaaaaatga tatcaaaaaa gtatatgtgc
    10861 tatgtggaga tccatatacc ataacaactg aaaaatggta tcaaaaacaa cgaccaatga
    10921 aaaaatgtct aagtaccaat gttcatgatt attgggaaat tgaagtgacg agcgaaacaa
    10981 gtcgcttaca gtatgcgttc catgttgttg gggaagataa cacggactgt ttttacggtg
    11041 atcaaggaat ttttccttat cgagaaaatg tgattactga accaaatttt tattttcgaa
    11101 taccttattt tcatcaaatc gatcgattca ctattccaga atgggtaaaa gaaacagtat
    11161 ggtatcaaat ttttcccgaa agatttgcaa acggggacaa agcaaatgac cccgaacaca
    11221 ctttaccttg gggaagtaaa gatccagacc gagaagactt tttcggggga gatttgcaag
    11281 gtgtgatgga tcatttggat tacttgacgg accttggcat caatggcatc tatttttgtc
    11341 ccatatttaa agccacatcc aatcataaat acgatacgat tgattattat gaggtggatc
    11401 ccgcttttgg cgataaaaaa cttttaaaaa acttgattga tgaagcacat aaaagaggga
    11461 tacgtatcat gttcgatgct gtattcaatc atatgggtgt ccattcacca cagtggcaag
    11521 acgttctcaa aaacggagaa aaatcgatct ataaagactg gttccacatc cgttttttcc
    11581 cagtagattc ttatcagatg actgacttac cagaaactgc tgaaaatatc ccatatgata
    11641 cttttgcttt tactccattc atgccgaaac taaatacagc aaatccagaa gtgcaaaaat
    11701 atttgctgga tatcgcaact tattggataa aagaattcga tattgatgga tggcgtcttg
    11761 atgttgctaa tgaagtcgat catcattttt ggaaaaaatt cagagaagca gttacagaaa
    11821 tcaaaccaga catctatatc cttggagaga tttggcattc ctctcaagct tggctgcaag
    11881 gggatgaatt ccatgcagtg atgaattatg catttacaga ttcgattaaa gattattttg
    11941 caaaaaagaa aatcacagct tcacaaatgg tcagtggaat gaatcatcag caaatgcttt
    12001 acagagatca ggtgaacgaa ggaacattca acttattaga ttctcatgat actgccagga
    12061 tcttgaccct ttgccaaggt aacaaagaat tgatgaagtc tgtgatggcc tttatgtttc
    12121 ttcaaaaagg gtctccttgt atctattacg ggacagaaat agggatgact ggtgaagatg
    12181 acccggattg ccgcaaatgt atgatatggg agaaggagga acaagatcta gagctattcg
    12241 gttttataaa agaacttgtt tctctaagga aacagttgtc taagattatt tctgaaggtt
    12301 ctactcagtg gctaatagta aatgatcgtg aagataagct ctatttcaca cggaaactag
    12361 agggacagat catctatgtt tactttaatc agtcaaaaga accttgggta gtagaacagg
    12421 aaaatgaggt gattcttagt caaaattgtc agttgttaga agacgggaaa gcagagatac
    12481 gacaatacgg atttttgatc atgtgttgaa aactgttacc ggtaacaaca agaaagcgtt
    12541 tgcaaatgaa gatttgtgcc cattataata agggtgtaac agcacgttga atacaaagga
    12601 ggaaatgaag atgaaaaaaa gaagtgtgaa acagttgggt ttagggttaa tctctttagg
    12661 aatcttaggc ggattagcgg cttgtggcaa tggtaactct tcagcagaag gggaagccga
    12721 tgaaggaaaa acgttaacag tttccgttga ttctggatat aaagattata taaacgaaat
    12781 aaaaaacact ttcgaaaaag aaaacgatgt gaaaatcaag ctagtagaaa aggacatgtt
    12841 cgatcagttg gaatcattag cgttagatgg gcctgctgga aagggacctg acgttatgat
    12901 ggcagcatat gaccggatcg gtgcgttagg acagcaagga catctggcgg aagtaaaact
    12961 gggaaatgaa gcagcttacg atgaaacaga caaagcccaa gtgacttatg atggaaaaat
    13021 ctacggagaa cctgcagtaa tcgagaccct tgttttgtac tataacaaag atttagtcga
    13081 tacagcacca tcaacgttta aagatttgga gaatctatcc aaagacagtc gttttgcttt
    13141 tgagtcagaa gcaggaaaaa atacaggatt tttagctaaa tggactgact tttattattc
    13201 ctatggttta attgcaggtt acggtggcta tgtatttggt gatgatggca caaatccttc
    13261 agatatcggt ttgaataatg caggtgctgt agaaggaatc tcttatgcaa cagattggtt
    13321 caaaaatgtt tggccaaagg gaatgcaaga cataaaaagt gcaggagact tcgccagcca
    13381 gcaattcatg tccaataaaa ctgcagcaat cattgacggt ccatggcaag cgcaaacata
    13441 caaagaaaac aatatcaatt atggtgtagc caaaattcct actctaaata atggacagcc
    13501 ttatcaaccg tttggcggag gaaaaggatg ggtagtcagc aattatgcta aaaacaaaga
    13561 cctctctcaa aaatggcttg attatgtaac gaatcaggaa aatcaagaaa aattctttga
    13621 aatggtaaat gaaatccctg caaaccaaca agctagggaa acagcaaagg ctaaaaacga
    13681 tgaattaaca acagctgtga ttgaacaata tgaaacagct caagcgatgc caaacatccc
    13741 agaaatgggc gaagtttgga caggtgcaga aaacttgatg ttcgatgcag catcaggttc
    13801 aaaaacacca aaagaatccg cagatgaagc agtaaaaaca atcagtgaag ccatagaaca
    13861 aaaatactga ttaaaatgat aaccgtccat ttttataaaa aatggaacag gtgcttcaga
    13921 taaaagtggc aagagcgaga tggaaaatta tcttgctctt gttgccatta tcttaaaagc
    13981 agtttgcggt ttagcaagtt tagagggggc attcagatgc agcaagataa aacaagcaat
    14041 atcaacgaaa aaaaaatcac gctttgttca cttattccag ggatggggca gtttgtaaat
    14101 ggccaagctt ttaaaggtat cgtttttttc gccatattcg tcctattcat tggtcagatg
    14161 cttctgggcg gatttcatgc attggtagga ttggttactt tgggaagtat accaatggaa
    14221 gatcattcat tatttatttt gattgaaggc actttgcaat tcatcattac aatcattttc
    14281 ttgatttttt acggtttgaa tcttttagac gcttatcgag tagcgaagat gcgtcaagag
    14341 ggcaaaaaaa tcaatcggac gatgaaggaa gtcatacata atataggtga tgaaggtttt
    14401 ccttatctat tgacacttcc cgcttatctt ctcatgattt ttacgatcat tttcccagtc
    14461 ctagttacat tgttcactgc atttactaat tatgacttca atcatattcc accagccagt
    14521 ttaattgatt gggtaggggc taaaaacttt tttagtatct tctttttaag ctcatatcgt
    14581 aatacttttt ttgcagtctt ttcgtggacc gtgatttgga ctttatgtgc aacaactttg
    14641 caaatcaccc ttggtattct cacagcggtt gttgctcacc agaaatttat taaattcaaa
    14701 cgtattttcg gtatcatttt cttattacca tgggcggtcc cagcttttat tactatcatg
    14761 agtttttcga atatattcaa cgatagcgta ggtgccatca atactcaagt gattcctttc
    14821 ataaaccagc ttccttttgt agatatcagt gcaatctctt ggaaaacgga cccgaactgg
    14881 acgaaagtag caattatctt agtgcagggc tggttaggat ttccctatat ctatgtgatg
    14941 gttacaggaa tcttacaatc gatttcagaa gacttatatg aagcagcaaa aatcgacgga
    15001 gcaaatgcat ggcagcgctt ttcaaacatc acgcttcctg ctgtcttcct agtggcagcg
    15061 ccaacattta ttacacagta tacggggaat ttcaataatt tctccatgat ctatctgttt
    15121 aacaatggcg gtcccggaag cgtaggcgga ggagctggtt ctactgatat tcttatttcc
    15181 tggatctata aacttacgac tggaacttct ccgcagtatt ctatggcttc agcaatcacg
    15241 ttgattatct ccgtcatcgt tatctgtgtg tcattgctgg tatttaaaaa gacaaatgcg
    15301 ttcaatatgg gggattaaca atgaaaaaat ttcattcgag tgctcgattc caaaaacgac
    15361 tttctcactt ttttacttac ttttttcttt taatactgtc agtcattatc atctatccgc
    15421 ttttgatcac agcaagtact gccttcaagt caggaaatat tgcagctttt agtttagatc
    15481 tttcaagtga ctggacttta ggaaacttta ctcggctatt cagtgaaaca ctttacggga
    15541 cttggtataa aaatacattg atcatttctg tcctaacaat gatcgtacaa gtgactgtag
    15601 taactttggc gggctatact tatagtcgct atcgttttat cggccgcaaa tcaagtctga
    15661 tgttcttttt agtgattcag atggtaccga ctatggcagc attgactgcc ttttatgtca
    15721 tggctttctt attagaagcg ctcgataagt actggttctt gacaatgatc tatataggcg
    15781 gtggaattcc aatgaatact tggctgatga aaggatactt tgacactgta ccaatagatt
    15841 tagatgaatc tgctaaactt gatggggcag ggcatttcag gatttttttc cagattgtat
    15901 taccgcttgt caaaccgatg ctcgccgttc aagcattatg ggcttttatg ggaccttttg
    15961 gggatttcat gttagctaag ttcctgcttc gaacacctga aaatcagact gttgctgtcg
    16021 gcttacaaac atttatttct gatgtgacaa accaaagagt ctctcttttt gctgctgggg
    16081 caattttgat tgcactaccg atttgtctat tattcttctt tttacaaaag aactttgtta
    16141 ccggcctgac atctggcgga acaaaaggat aggagcagag tatcatgcaa acatttccgt
    16201 taaactattt ttccgcatta cgtacgccaa ctcaagtgtt tgcgggacgc aaactattat
    16261 catggcctaa atttttcttg atatttgtat ttttagtttc cttgatggtc atgcctgtga
    16321 ctctttttta tgccaatcag atccaagcga ttccattaga acaatttcta tccgttcatt
    16381 cgctgatcga tgaacaagga acccaaaaat tttctgaact tgaattatct gaaactgggt
    16441 tacaagcatc gcaacaaacg atagctgtga cccctgaaat tttggtaggt gtgtctttat
    16501 ctgagaaaca acaatccgat catggaactt ttattgattt tgagaaggaa caatgggtga
    16561 tccaacaaaa ggataaatct ggtatacgcc gctatacgat gaattatagc ccatctttcc
    16621 aaccagattc tgtacgtacg cccgaagatt tccaacgatt tttagaaaga gaattttatg
    16681 ccagtaatcg tccaacaatc attttatctt atagtttaag tcttggtctt gtcctatttg
    16741 tcatgacgag tctcatttta ttcggggctt cctttttctt gtggatgaca agaaaaagcc
    16801 aactttcatc cattcataca ttcaaagaga gtgcaaattt gatgctgaat gttatgggaa
    16861 taggttccat ggcagcagca gttgtagggt ttatccactt tgactttatc ttgatgctaa
    16921 gtgtccaaac aacgataact gtcttgctgc ttttatgggt ttttgtcaaa acaagattca
    16981 aagataagcg tgtcgaatga caagtttaag cgatttatgc gacaatgaat gtgaaaaaaa
    17041 tgaaaaataa agtagttttt gaaaaatttc tgaaaaaatt aaacttctta gttgattctt
    17101 ttctttttta gtattaacgt aatagggtag tttttttaag gaggaaaatc atgttagaga
    17161 aaactttata caatcaatta ttttcacgtt ctttctcgct ccctgtcgaa gtaaattatt
    17221 gggacggtac aacgaaacaa tacggagata cggacactcc tccccaaatc aaaatcaata
    17281 tccatgaaga aatcccaatg aaagagatta caagtaacgc atctttggca ctaggagaag
    17341 cctatatgga tcatcgaatc gagatcgagg gaagtatcca agcattgatc aacgatgctt
    17401 atcagcaagc aaacagcttt ttacgaggaa aagattatct aaaatggctg ccaaagaaag
    17461 aaaaacatac gaaacaaaaa aacaaagaag atatccatgc gcattatgac ttaggtaacg
    17521 acttttataa actttggcta gatccaactt tgacttattc ttgtgcttat ttcaatacac
    17581 ctgaagatac gttggaacaa gcacaaatca ataaagtcca tcatatctta gacaaactct
    17641 ttatcaaaga aggcgaaacg ttgcttgata tcggttgtgg ctggggaaca ttgatgttca
    17701 ctgctaccaa agagtataat gtcaaggcaa ctgggatcac actaagtgaa gaacaatacg
    17761 atttgattac caaaagaata aaagaagaac atttagaaga taaatgccgt gtattattaa
    17821 tggattaccg cgaactaaaa ggcgaaacgt ttgatcatat cacaagtgta ggtatgttcg
    17881 aacatgtagg ttctgaaaat cttgaaggtt atttcaaagt ggtaaaagat ttattgaaac
    17941 caaaaggaac agctttgatc catggaatca gccgacaaca aggcggtgcg acaaatgctt
    18001 ggatcaataa atatattttc cctggcggtt atgtccctgg tgttactgaa ttagttgata
    18061 atattacaaa aaacgatttg caactgattg atttggaaag cttacgtcgt gactaccaat
    18121 tgacattaga acattggaca aagaattttc atcaagtcca agatcaagtc acgaaagaaa
    18181 tgggtgattc cttctatcga atgtgggatc tatatttaca agcttgtgca gcttcatttg
    18241 aatcaagtaa tatcgatgtg attcaatatt tgcttgttca acctggaaac aatgacatcc
    18301 caatgcatcg tgcataattg aggcaaaagt actgtttaaa gactatttaa aaagaagcta
    18361 agttttatga tgctccagaa gtgaactttt ttgtctaact tctaggattg tctctaaagc
    18421 ttagtttctt tttctttata ttttcataat aaaagtttgg ttctttaatt tttaaacatg
    18481 acagaaaatt ttttcttcgt tatacttgta atagaatact attttataac aaaggggatc
    18541 gaatcaatga aaaaaactgt tatttatact agtttatttg cagctttgtt tttagctgct
    18601 tgtcaatcaa ataccaatca aggcacatct gggaatacgt cttccagtag cgaacagcgc
    18661 tcttcacagg tatcggactc ctcaacaaaa gcaagcacat cttcgtctag ccagacaaaa
    18721 agttctagtg aagcaagtac tcagtcagat atcaaagtgt ctgcagctcg tgcgatcgaa
    18781 ttgttccaag ataaataccc agatactgca attactagtt tggaattaga tagtgattgg
    18841 ggatcttact tctacaagat agaaggtgtc gatgatcaaa aagaatacga agcaagaatt
    18901 gatgctcaaa atgaaaaaat ggagacagag aatccagaaa ctctagatcg agatgaacaa
    18961 aatggtcaaa agaaaaaaga agatggtctg gatgttgata aattgatcac gattgaggaa
    19021 gcagcaaaaa tcgccgtcga caaagtagga agcggtacgg caacagattg ggatttggat
    19081 aaagatttag gtactactta ttgggaagtc aaagtaaaag acggcaatca aagtacatca
    19141 gtcaagatca atagccaaac aggcgaagta ctgtcaactg aacaagatga ttaagaattt
    19201 cttcggaaaa caagagttga tttttctttt agtcatgata cactagacaa aataacttgt
    19261 ttgaaggagc gatttacttg agtttagaaa cgacctttgc caatcatatc tttgccaatc
    19321 ctttgatgaa tgcatctggt gtccactgca tgactaccca ggaattagat gaactggctc
    19381 attcagaagc aggagcattt atcactaaga gctgtacgat caatgaacga aaaggaaatc
    19441 ccgaaccacg ctattttgat gttcctttag ggagtatcaa ttctatggga cttccaaact
    19501 taggtttttc ttattatcta gagtatgctc ttgcgtatga aaaagtgcag gaaaaccaaa
    19561 atcaaccgtt atttttttcc attgccggga tgagtgtcca ggaaaacttg gaaatgcttg
    19621 agaaaataga aaaaagtggg tttaatggga tcactgaatt aaatttatct tgtcccaatg
    19681 tgcctggaaa accacaacta gcttacgatt ttgaggccac ttatgaaaca ctgaaagaag
    19741 tattcagcat cttttctaag ccgctaggaa tcaaattgcc tccttatttt gattttgctc
    19801 attttgatca gatggctgat atcttgaatc agtttccatt gacctatgtc aatgctatca
    19861 acagtgtggg caatggtttg tatatcgata cagaacaaga agcagtagtc atcaaaccaa
    19921 aagaagggtt cggcggcatt ggcggagagt atatcaagcc gactgctttg gcgaatgttc
    19981 gcgcttttta tacacgtttg aaaccagaaa tccaaatcat tggtacaggt gggattcgga
    20041 caggacaaga tgcatttgaa catctgctat gtggcgcaag catgttacag attggtaccg
    20101 agcttcataa agaagggccg gaaatttttt ctagaatcat aaaagaatta acgcagatta
    20161 tgtcagaaaa aggatatacg tcaattgacg aatttaaagg caaattacgc accatttcat
    20221 agcaaagaga cgaaggtcat gattgatctt cgtctttttt tataaaaaac actcgtctgt
    20281 tcattcctgt gcaagcgtac tcattgtatg ttagacgaac ttgtgggaaa ataacagagg
    20341 caaaaaggag gataatatga atgatgcaac agaattagca aaagagctta aagaaaaaga
    20401 atttagtttt caagaactag ttacggatat acagaaaaaa ataaagaagc aaaatcatga
    20461 attgaatgcg tttgtcgcgc ttgaaccatt cgagagtaat tcccacgagc tattgattcc
    20521 ccagtcagaa aaagggccat tggctggtat cccatttcct ttaaaaatgc tcggtcaaga
    20581 aaaaaaggga tggctagcta cttcaggatc tcgtttattt gaaacacacc gagcttctca
    20641 tacatctaat tatgtgcggc aagcagaagc gataggtcta gttccttttg gacaaaccaa
    20701 tgcgccagag tttggtttca aaaatattac agacccagtc atctatggcc cagcaagaaa
    20761 cccttggaac cttgaatgta caccgggcgg atcaagtgga ggagctgctg ctgcagtttc
    20821 atcaggaatc gttcctttag ctggtgctag tgatggcggt ggttctatta gaatacccgc
    20881 ttcgttttgc ggattgattg ggctgaaacc ttcgcgaggg acgatgccag ttggtccata
    20941 tgcttggaga ggatggcaag gagctgctat tgatttcggc ttgacagttt ctatgagaga
    21001 cacggaggct ttattttatg ggatgagaag tatccattcc ggtgcgccat atcaagtatc
    21061 gccagttgag tggcaaacac atccaagaaa aaaacggttg aagatagctt tttgtgttga
    21121 ttcaccgatc cactcacaga ttagtgaaga ggcagtactt gctgtaaaaa aagctgtaga
    21181 tttccttgga aaagaagggc atgatttgac agagattcct tacccactag atggtcgtaa
    21241 actgatcacg tcttattatc agatgaatgg cgcagaaaca gcagcaatga tccgctcgat
    21301 tgaaacaggc atccagcgag ctgtcagaaa agaagaactt gaacccattt cttggacttt
    21361 gttccaatat ggtcagaagc tctctgccgc tacttacatc gattctctgc atgtatggga
    21421 tgaagcagca attgtcatgg aaaacctaca tcaagaatac gatctattcc tttcaccaac
    21481 gactgcattt accgccccta aaatcagcga agatttgcaa agtgatgcga taagagcaca
    21541 gatggaacac atcagtgatt gttctgaagt agaaggttta gacgttgttt cttccatgtt
    21601 tgaggagagc ttgaagatca caccttatac acagttggct aatctgactg gacaaccagc
    21661 aatcagcttg cctactcatt tgacaaaaga aaacatgcct ctaggaatcc aatttatggc
    21721 tgccagagga agagaagatt tgctatttca aatcggctat ctatttgaag caaatcatca
    21781 gttccattta ccaaatccat ggaaatagca gaaacaagga gaagaagaat gaagaaaaaa
    21841 agattgtttg ctctaataac tagtgccttt tttattttaa gcgcttgcgg tacagctgcc
    21901 gctaatcagg aagataacag ctggagtaat gtagaaaaaa agaaagaatt agtagtagcg
    21961 acttctggca cactgtttcc cgcatcttat tataatgatc aaaatgaatt agttggttat
    22021 gatgtagatt tggcaaaaga ggtggctaaa cggttaaatg tcaaaatctc ctttaaagaa
    22081 tacaacgtgg atggacaaat cacttctgtt tcaaaaagag aatcagattt tgctgcgaac
    22141 gattttggta tcacaaaaga aagagaaaaa aaattctccc tttcagagac tttcaaatat
    22201 tcatttgaca gtatgatcgt acgaaaaaaa gatgattcag gaatccactc acttgaagat
    22261 cttaaaggga aaaaagcagc tggcgaaccc aatactagct atatgcgttt agcggaaaaa
    22321 cacggagcta aattagtcac atatgacaat gccacgaatg atcagtattt aagcgatgta
    22381 gcaaatggtc gaacagatgt tattctaaat gattattatc tgcagaaaat ggccgtatct
    22441 gctttaccag atatccctgt aaaaatactg gagaacgttt atttcaatga aaacgaaagt
    22501 ggttttttat tgaaagaagg aaatgatgct ctgaaaaaga aaatcgatgg cgtattaaaa
    22561 gagatgaaag aagatgggac gacaaagaaa atatctgaaa aatattttca aactgatgtt
    22621 tcagtcaaac cgaaagaaac gatggctgag tcggtgagtg agtgatgtac tttcctctaa
    22681 ttgatttttc cctcatgtgg acttcacttc ctttcgtact gcaaggcttg gtatacacat
    22741 tagggattgg cttcgtgtcg tttcttttag gaaatctggt agggttgctt ttgacagttt
    22801 taggtctttt ggattggctg cctctgaatg tatttattcg tttttattta tcgttcttta
    22861 gaggcattcc cgcactagtc ctgctgtttc tgttatattt tgggttacct tatcaattaa
    22921 gtgccttaac ggcttcagtc atctgcttta cgattaccag cagtgcattt attggtgaaa
    22981 tctatcgagg atcactagca ggcgtttctt caggtcagtg ggacgctggt ttagcttctg
    23041 gtttttcttt ctttggggta ttgaaatata tcgttttgcc gcaagctttt cgaatctcag
    23101 taccggcact cagtaacgta gctatggatc tagtgaaagg tacttcgtta gcagcaacaa
    23161 tcacagtgcc agaaatattt caaaaagcaa agatcatagg cggtcggaca ttcgattatt
    23221 tttctctcta tattttagtt gcactgattt attgggtcat ttgtatcggg atcgaaaaag
    23281 tgcaacagta tttagaaaaa cgttctatgc atcagtcaat ctgaaaaata gaaatggtgc
    23341 tagcgtggct ggcaccattt ctattttttg tttcttgtat attctgccta gtattttaaa
    23401 accatttcat gtaaaatgta aatcgaaaat atgttcggag gtagaaaaca tgaagacccc
    23461 gctaaccatc gaaatagaat cctcgttata ccaatattgc atcgagcaag gcggcttggt
    23521 tgtagaagaa gtcacgatgc ctgatgacca aggaattgta gatacgctta gctgcttgac
    23581 aaaatttgat ggaagccgag aatggcgatg ctatgagctg aaagtgacaa aagcagattt
    23641 tcgctctaca gccaaactgt catttgttgg acattataat tattttgttt taccaagtaa
    23701 actatatgaa gaagtaaaaa ctgaaatccc tacaggaata ggtgttttag tgtatcgtcc
    23761 gtacacggtt gaagaggaga tgcctgcctc tggtacattt ctgattgcga aaaaagcagc
    23821 aaagaaagag cttgctgtac cggaagaagc tttgacaaac cgcttcatgg cttctttatt
    23881 cagggaagta agaaaagcaa agcaaatgga gcgaggcgta aaatattttc caacagatca
    23941 attgtacaaa gaattgaaaa gacgttcaga aaatcaagat ccattttcta acgaacgata
    24001 ttatgaacgg tttttagagg aaatagctag tcaggcaatc aatgagttgc aagaagaagt
    24061 tatcgcgctt cagcatgatt atgaatattt gaggcaacaa cagcagatcc gtcggttgcc
    24121 tacagagcca ttggagtgaa aaatatgtac tatccttatt taagaggaaa acaatttgac
    24181 ctattagcat taaaagaagc actgtcgcga ggattgctct ccaataaaat ccaaccagtg
    24241 atcgaaccag tacgtgattc cgctacgctt aaaaatgtga tcgaattatt tcaaaaaaag
    24301 caccatcgaa tcgctgtgat ccaaaatccc caagtaggac aattcaaatt attcgatcag
    24361 catgtgcaca gttggacagt caaagaaaat agctctgtcg tccctgcaca gatcttaacg
    24421 ccagaaaatc tcagtgaagt actggattca cctccagcgt ttcttgtttt cgatggacag
    24481 cactacccaa aagatacaga ggtgtggaaa cagttggcag gagttgattc gaaatttttg
    24541 ataccagata ctagtcgctt tcgcatctgg ctgcccgaaa acaaaattgt gatccgtgac
    24601 tcttttcaaa cgagaaagca tgttgaaagt tatgcagata aaacagatga cttttttagt
    24661 gatgactatc tttttttcca cgcagacgga tatattggat tttctgattt cacgatcgaa
    24721 ggtagccgtt atttcgataa agggttccct agccgagcgc ttgctatcca tctaacgtat
    24781 attgatgctt acggcaatat acgcgtgaaa cattttgtct ctgacagtaa cgactctgct
    24841 aaagaccaag cattgaagtt tcttgaagca ggagataaaa tgaaaaaatg gatcatgcgt
    24901 caccatcatc aactcttgat tacttcagga atgattgaat tattggctct ttaccagcaa
    24961 caaaaattcc ctggactggg agtgttgaaa aagtggtcac ttatgcatca tttggaactt
    25021 attagtcacc tgctagatca tccaaaagat tggcttaaat attattcaaa agttcaggaa
    25081 ctatatgaag tgatccaatg attagataat gtaaatgaaa aaggaataga aaagaggaaa
    25141 ctggatgtat attcggcaaa caaggaaaga agaagtagaa gaagtggtag aaatcattaa
    25201 tgccgcagcg gatttcattg cttcgcaagg ctctcctcaa tggcaaaacg ggcagaaacc
    25261 aacaaaagaa acgattttga acgatattga aagaaaagaa agctatgtat taatagtgga
    25321 agatcaaatt gctggaacag ctgcattagt ctcaagcgtg gatcccgttt acacaaaaat
    25381 agatggtagt tggaaagaat caactggtcc ttatttatcg attcatcgtg tcgctttagc
    25441 agaaagtact cgaggaaaaa aactagcaaa accgttctta gaacatttgt tgacgattgc
    25501 agccagcaaa aatatccaag atatccgtat cgatacttat ccagctaatg aaccgatgga
    25561 aaagaccatc tattctgctg gattcactta tcaagggatg attgaatttc cttttgaaca
    25621 cggcgaaaga aaagcatatc aaataatcat caattgacta taaaatcatc tgagcaaaga
    25681 taaagacatt aacactactg aaaaaaacaa tcatatgata gccaagaggt tgtaacagaa
    25741 gtggccagct tcaaaaaaca agaaagaatt tccgaaaatg cttctcaaat ttttgtggaa
    25801 ttttagcgta ttttacgaaa tagctgcttt ctgaaactcc cttcatcgag aggtcgtgac
    25861 atagcttttg tcacgacctc tcggcttatc ctacgagtat tattcgatac atttatatca
    25921 ataatccttt ttttatttta tctgcagctt cttggaacgc tccatcgttt gacacgacta
    25981 aaagtgaggg gatagctttc aaacgtttca actgtgctaa atcttctaca taaaccgcca
    26041 gtctggctga aatctgttca gatgaatctc cacgtttttt caggcgcgat tgcaatgttt
    26101 ctttagagat cgtaataaag ataggacgga ctaccgtccc gaaatactca tataaatgcc
    26161 aaaaaccatt tgctgtcaaa acggcgtaac aatttcctac tgtcagtttc tttttaattt
    26221 ctgctttact ggaaccatat ttatgttgag catattggtc ccactctgca aactcatttc
    26281 ccttgatcat ctgattgaat gtattgtcag aaacaaaata ataatcctct tgatcttttt
    26341 ccccaggtct tggtgatcga ttcgtgtaag taatgatctt ttgttccggc tgaaaaatag
    26401 cttctgcgag tgaagttttt ccagaaccag aaggaccgat aaatacatag caataattca
    26461 ttgtcatttc tcctttgatg attgaacaag tgaaaaagct ttggaaaata tttccaaagc
    26521 ttttaaaagt aactttgctt ttttgtatat tataccagca agccagtcac aatagcactt
    26581 aaaaagctga ctaaagtcgc tgttagcaaa attttcaatc cgtgttttgc gacaagattt
    26641 cctttttctt catttaatcc cttcatcgca ccagaaatga tcccgataga agagaagttg
    26701 gcaaatgaaa cgaggaagac agatataatt gctgttgtac gctcagtaaa atggaaatta
    26761 ccatttgcta attctgtcat agcaacaaat tcatttgtaa ccagtttagt cgccatgata
    26821 ctaccggcat ccactgcttc tttccatggg attccgctga tgaaggcaag aggggcaaag
    26881 atgtaaccta ggatctcttg gaaagtgatg ccgaatatcc cgtggaagat agcattgatc
    26941 atggcaatca aagcaacaaa accgataagc atagcagcaa ccgtgatcgc cacatggaaa
    27001 ccatcaagaa tgtattctcc caacatttgg aaaaatgtct gttctttgtt ttcttcaatg
    27061 atcagctcat cttctttttc ttctaataca tagggattta caattgaagc cagaatataa
    27121 ccgccaaata agttcaaaac aagggcagtg atcacatatt tagaatcgat cagtgccata
    27181 taagatccga cgatcgacat agaaactgta gacatagccg atacactcat ggtgaacaaa
    27241 cgtttctcag ataggaaggg taattccttt tttatggaaa taaaaacttc cgattgtcct
    27301 aaaatagcag aagctactcc attataagat tccaatttgc ccatcccgtt gattttactt
    27361 aatcctagac caacagcttt cataaataat ggaagaatct tgatatagcg tagaataccg
    27421 ataatagcag aaataaatac aattggcatc aatacggaaa gaaagaaagg tgcacttcct
    27481 ttatttgcta caccggcaaa aacaaagtca acaccttgcc cagcaaaagc aagaagatga
    27541 tcaaacattt ttgccaatac agaaacaacc gctgtaccaa aagttgtacg taataatacg
    27601 aaaccaagaa caagctgtaa aacgaacatc acaattagtg gtttcaattt gattgctttt
    27661 ttgttactgc tgatcaaaaa agcaagccct aatgtgacaa ataaaccaat aatacctaat
    27721 aaataactca aataatcact cctattccaa attccgtttt attttacctg ttttgcaaat
    27781 aaaatactaa tctttagtga aattttcatt acttttttag agtgaaacgc attcattttc
    27841 cattagaaaa taaagcgaac aaaataaaag gtttaaaaag tgtaacgtct tagtaaagtc
    27901 tataaaaaaa cgaaactatc gattaagcta atagtttcgt tttcaacatt tataagtaaa
    27961 ctttttctat tggtaatata gattttcgga agggtagaca ggtgcgcagg taatatcgat
    28021 tcctagtttt ttcaatgttt gttcatcatt tttattgacc atcacagtag agtgggcttg
    28081 tgctccctca agttcagcta gtttatcata agcaacttga gcgattggat tcgttactgc
    28141 actgattgat aaagcgatca agacttcatt gatgcttagt gcatccaaag aggaatgaag
    28201 tgtctttgat ttcaatcctt gtattgtttc aagaactaat ggtgacaata aaggaatgtc
    28261 atctgcgata tgggctaaat gttttactgc atttaagata actgccgctg acgcatccat
    28321 caatgaactt gtacgcccgg taatgatgac ttcatctggt aattcgattg caatcacagc
    28381 agaaggatct tttgtaggac tttgcgcttg aatcttatct gcatagtcat gggcagggac
    28441 taccacgttt cggtcttcag gacgtaaacc gacttcttcc ataatcagtt tgattcgatt
    28501 aactgcttct tcgtcgatca atcctttttt gaagtcgcat tctgtttgga aataacgacg
    28561 gatgatttct tgtttagagg cttcttggac aacggtatca tccacgatcc caaatcctac
    28621 acgattcaca cccatgtcag taggagattg ataaacagat tctttaccag taattttttc
    28681 aataatacgt ttgattacag gaaatgtctc aacatcccga ttatagttca cagctacttt
    28741 attgtaggca tcaaagtgga aggaatcgat catattgaca tcttttagat cgactgtggc
    28801 tgcttcataa gcaatgttca gcggatgttt caacggaaca ttccatactg ggaaagtttc
    28861 gaacttggag taaccagctg catgtccttt ttggctttca tgatacagtt ggttcaagga
    28921 agtagcgagc tttccacttc ctgggccagg agctgtcact acaacgattg gtttagttgt
    28981 ttcaatatac tcattttttc caaaaccatc ttctgagacg attttttcta cgttgactgg
    29041 atagtcttcg atttctgagt gtttatagac cttgatgttt cgtctttcta gtttattgat
    29101 aaagactttc gtggcaggct gtccactata gcgagtgata acgacactgt tgattaataa
    29161 gccataacca cgtaattcat cgattaaccg caagatatcc atatcataag taatcccata
    29221 atcaccacgg atcttattac gttcaatatc tccagcatag acgcaaatca gtatttcagc
    29281 ttgatctttc aatttttgca gcaatttgat tttcgcatct tcttcaaatc ctggaagtac
    29341 acgtttcgca tgcttgtcgt caactagctt cccaccaaat tctaaatata atttgtcata
    29401 gtggttcact cgttccaaaa tatacgctga ctgctcttca atatattttt ctgaatcaaa
    29461 accaattttt ttcactaggt tccctcctta agtactaaag cattttttca tttttttgag
    29521 gattcgtcaa ctggaagagc gaaattcctc aaaaaaacaa agaaaatggt ttaaaccaac
    29581 ttgtctagat agttattcat tggtatgata gtttttgata aggaaggtgc tacatgaaaa
    29641 aaagacagaa aaagaaaaac gcatataaac actatatccg ttcgattttt accggttatg
    29701 aaagaatgct tgaagatccc gaattggaac aattgacgtt tacttatcta aacgaagaaa
    29761 cgcagctaac tcgtgatgag catcagcgca ttcatttcac aacaagagat ctgcctagta
    29821 aataaaaaat aagataaagg tcatcggatt cgattctgtc ctatcagatg gaaagactag
    29881 ttgatcgaaa aaaaggctgt accaaatttt ggtgcagcct gttttatgga gcattgcccg
    29941 ctctttttta taacaatttt ttacagaaaa tggtactatt gaagtattaa taagtgaaaa
    30001 acagatgagt aagaggaggc aagtagtatg aaagagccag atacaaatgc aaattatgag
    30061 ccagacgaac tagaggagac gaatgcggat caggatacag gacaagaatc gtcttctttt
    30121 tacgatatca aagaaaaagc aagcatgaat ctttcccaat tattagaaga cttacaggct
    30181 tttgaaaaag ctgtccgcga agaagatatc cctgagatct accgtttata caatggccga
    30241 ttgaatgaag aattaaaaag aagctcaaat gaaaatcacg agatcgatca attgctgatg
    30301 cgtaagatcc atgatcgttt tttacaggaa tttcctttta tggaacaagt agaaaacatc
    30361 tcgccaacga tgagctatta caaaatcggc acttattacc atgatcggcc cacggtcggt
    30421 attgatgcaa gtctgccaga aatttttgtt ttgcctaaga tcgatgaaga gtgggagaaa
    30481 tattcccaac cggagtcaac ggactatgac aaaaaaatca atgagctaga cgcaaaggtg
    30541 atcactgctc agacagaaat tgaacgttta gatgaacaaa taaaagaaat caatcgacaa
    30601 atgactgatt tgaacgacaa taaaggattc ttgaatcgta aaaaaatcga ggaagaaatt
    30661 caagaattag agaagaagaa gcaagtacta tctaatgaaa aattaggctg gcttccttat
    30721 attgagacgc ctgaaacaat ccagcagcaa aaagaagcat tgaagcaaga agcaagagca
    30781 gaccagcttc gtgcagccat cgtagaaaaa gaacaaaggc aaatcagacg ctatttcggt
    30841 agcaaagagg gattcggtca agcaatccat gaattcttga tgaattatct tggcaatgag
    30901 aatcctaata atcaatctaa tgaaggaggt tccgagtatg aatgaacacg atgaagcaga
    30961 atggacaaaa aatgaagaac aaacagaaga tcatgaagaa acgaacactt cattggaaga
    31021 acaaacaagt aatcctctgg atgacacaga agaaatccct atgctagagg aaacaaaaat
    31081 acacgaaaaa gaaaaagtaa ctccgacgaa tacgaatact gcagaaaaca cccatgctta
    31141 cgaaataact gaaaatcccg ggtatttaga aggaaaagag caagatcatc aagatatcgt
    31201 cagtttgatt gaaacagcgg aagcagaatt agcggattta cgtatgagaa aagatttgat
    31261 cgaatcagat tttccacaat tattagaatc atatgatcgt tttatattga atgaagaacc
    31321 aatctccacg atcggaaaga caagcctgat cgaatacttc acgtatgaat tactgaaacc
    31381 gttgaatgat attggtctgg aacggtcaaa ttcagcttat gacacatgga aaacaagaca
    31441 tttttcgatc aattatacgt tgaatggaca aaacgaatta gtcttttcct ttgtattacc
    31501 gaccatcgat caacgatacc aagtggaatc gatgagtctc ctaaacgtat caccagagac
    31561 aatggaaatc aatgtccaag atgaccgggt gctttctttg atccgacact ggtcagtgga
    31621 tcgagtattc tctgcagggc agatcacgat attcaatcac aaattgaatc aattattagc
    31681 ccatgcaaga acacttggtt ttaccgttaa tcagacatta ctagacaata cgaagccact
    31741 tcgtttgaat cttcagagcg aatttgaatt gacgaatgaa gtattggatg atatttttat
    31801 cgtggcaatg aaaaatccat cctacgatat ggaaaagatc aacgaaacta cttatcaagt
    31861 acgattagat aaaggacagt ctttaacgat aacaacaaac gaaaaagatc aaacagtctt
    31921 gtcgatctca tctggagact acccacgatc tgtcattgat ttctttatca attacgaatt
    31981 cttggtccca ttaatggtga gaaagtcctg attggataag ttggattacc agatgtcatt
    32041 cagataattc tgttccaaag gacttgcggc agttatccag aataattgtc acaagtcttt
    32101 tctgtatgta ctaaatggac gtgaataact tgctgatgaa ggagggattt cattaggaat
    32161 gtccacaaat aaaatagcac agcttagctt attgtctgct gcttgtgtag caggtaggat
    32221 cgcttttcaa tttattccga atttccagcc aatgactgct atttttttat ttatagtact
    32281 ttacttaagc ttaaaagatg cgttaattgt catgagtctt tctattgcga tcagcagttt
    32341 ttattttggt gttggaccat gggtcatcgg ccaatggatc agctatactg ttgttctgag
    32401 tttgttttca atcgtctgct tgagaaaaac agtgcaaagg aatctatggt taaagggagt
    32461 ctgttttttt ctggcgggca tggtttacgg aataggtatg accgtttttg atacgctgtt
    32521 atatcgtttg cctcaacctt ggatctatta ccttcaaggg gtgtcgtttg atttgatgca
    32581 cagtataggc aatgttgtgt tctttcttgt ttttctgcca gtcgtcaaac gtttttacaa
    32641 tcattcagga ggaaaaaatg aaaaaaataa tttatagttt gcttgcaatg agtgtcagta
    32701 tactcatttt gacaagttgc agtacaacct atacacaatc ggcttccaac caaaaggagg
    32761 aagtaaaaac atcgcaaaaa gcaacaatca cgttacaaga aaatggtcaa aacttttcgg
    32821 aaaaagaagt gttcttcaaa aaaggcgatg atttactgag tattttgaaa cgaaattttg
    32881 aagtcaaaga agataacggc ttcatcactt cgcttgaagg gcactcacag gatgagaaaa
    32941 atcaactcta ttggatgttt actgtggacg ggaaaagtgc tactactggt gccaaagaga
    33001 tcaaattgaa tgatggacaa tcggtcattt tcaatttgtc taaactataa gtttcataaa
    33061 aaactgttaa agggcgaata ttgccataat tcagtgagtt cagttgatga aagaaggaaa
    33121 ataacatgga aaattttaaa aaaagcggaa tgttttccgt aattgctgct ctaggggcta
    33181 atattctagt tgctatcagc aaatttgtcg gctatgcaat cagtggcagt gccgccatgc
    33241 taaacgaaag catccacagt atcgttgatt gcagcaatca gattttgctg ttattcggtg
    33301 ataaacaagc caataaagga cagagcgagt tgcatcaatt tggtgaagga cgagcaaaat
    33361 actttttcag tacaatcgtc gcaatgatgc ttttcttcgg cggtggggca cttggggtga
    33421 tggaagcttt tgaaaagttg acgcatccat cccatgaagt gggtaatccg atcattgtta
    33481 tagcaatact gttatttggt ttggtaatcg aaggaagttc gttacgcgtg gcaatgaaag
    33541 aaatcaaaga attgaatact gaaaaacttt ccacgatgcg ctttttgcgc gaaagtcgac
    33601 acagtgaaat actgattatt tttacggaag acttgtgtgc tgtaatcggt ttggtcttgg
    33661 ctttagcagg aacaatattg acttatgcaa ccgggattgc tgcatttgat gcgatcagcg
    33721 gattgctgat cggtttcttg ctgatgggag ccgccatttt cctagcaaaa gaattttata
    33781 gtctgatcat cggtgaaagc gtgacagcaa gcgatttatc aaaaatcaag ttagcttttg
    33841 aacgtcctga gatcagtcgg ctgatcgata taaaaacagt tcatttaagt ccaacggaga
    33901 ttttagttgc agcaaaagca gatatcgttg gtaacaaaga gaatgaagct tactcggtca
    33961 tcaatgatat tgaaaaaaat atgcgtcagt ctcttcctga caagaagatg tatatataca
    34021 ttgaaacaga taaatatgac ccaaattatt ctcgtaaata aaacgtttat tcatgaattg
    34081 aagcaaaaat gagaaaaata taatcttgtt tttaaataaa acggctacaa tttagcgaat
    34141 ttatgttaca atgagtccgc tgtttatttg ttgtaattaa aggagatatt ttaatgaaca
    34201 aaaagaaaag tgcgccatgg cttcaagctt tgcatgcagt gatgccactt tgtataagct
    34261 atataccagt aggattagct tgcggagtat tgttgcaaaa agttggattt gatcctctct
    34321 tatcaggact gttatcgatt ctggtctttt ccggtggcgc gcagttttta gttgcatcta
    34381 tgcttacgac gcaagcatca tttgcaacga cattattgat ggttttcttt ttagaattac
    34441 gctatacatt attaggagca agtcttgccg gttttatgaa aaaagaaaag cggacgtttt
    34501 tggctgtctt ttctcaatca ctgaatgatg aaaactatgc ggtgaactac ttaaagtttt
    34561 caactgaccc ttcctggaat aaaagaaagg ctttatatgt caattggttc tcaatgactg
    34621 catgggccgg tagcaatatg atcggtaatt ttttcggctc ggtgattcga gtagatgctg
    34681 accttgtcca ttttgctttg acggccatgt tcattttcat gtttatcatg cagatgaaaa
    34741 gcgcactact gatctttaca ggtttattct caggcgtatt aggggtcgta ttcatggtat
    34801 tattccaaaa tactttcgga ttgattgcag caacagtcat tgcttcattt gccggattta
    34861 tgctggagaa ggcattcaaa aaagaaaaag ctaagaaact aagagaccgc ggtaaagatg
    34921 tcaatgagcc gctcttcaac ttcccggaac aggaggccaa tcaccatgac taaactatat
    34981 ttgctacttt tagttgcttg tctgttcatc gtggcatata tcccgcgctt gttcccgatg
    35041 ctttatttta ctcatcgaaa agtgccatcc tggttcagtg actggatgaa atatgtaccg
    35101 gtggcattat ttgcggcgtt agcttttaaa gatgttttca ttactcatga acatctggat
    35161 attgcttgga atatcaaaat agctgcaatg attctagtag caggcgtggc ttacaaaaca
    35221 cgttcgatgg cgttgtcagt tttgacagga cttgcgtctg tctttttgct gtctatgctt
    35281 taaactgttt tattttatta aaaacagaga ttgcgacata agttgttcaa actgatctat
    35341 ccgaactgca tttgcaacag tcaattctgg atgcaagttt attcgtaggg ataaaaaaga
    35401 ttagtgttgg cttatgatgc aagctctttt ttattttagg aattagagag ggatttgtcc
    35461 ttctatgatt ttttgctata atagggaaga tgtttatttt atgaaagaat agttgaggga
    35521 atttaaatga ataaaaaatt gatgcaagga acattttggc taacctttgc taatcttcta
    35581 tgtaaagttt taggggtagt ctatttgatt ccctggctaa gtatgatggg gaacaatcaa
    35641 gatggtatgc ttgctacgac attgtataat gttggctatc ttccttatgg attgttcctg
    35701 atgcttggta cagtcggatt tccaaatgcg attgcaaaaa aagtagctgt agccacaaaa
    35761 gaaggagata acgctgcttg tcggctgatt tttagaagta cgatcaatat catgtttgtc
    35821 atcggtatcg cctctgctgc actgatgtat ttatttgctc ctttactagc cggaatcagt
    35881 ccgattgcta acgttaataa tgggatacta gctatcagaa gtttatgccc atctttgatt
    35941 gctatcccaa ttcttagtgc aatgagagga tatttccaag gaaaaaatga tctgcggcct
    36001 tatggaactt ctttgattat cgaacaggct gtgcgagtga tcgttatctt ggctggtact
    36061 tattacttgc gcgtattgac tgacggaacc atattagaag ctgtattgat cagtacagtc
    36121 gcttctttct tcggtgggtt agctgcgatt atccatatgt atatcgtcgg acgcagaaaa
    36181 gacttcttcg aacttaaaga ttttttgatt tccagccgtt atttcgaaag agaaaaccga
    36241 tctgcctctg tctctatcat tcgggaaaca ctaccgttta tttttgtcgg ctcagtcatt
    36301 actatcgttc aaatgatcga ccaagtaacg atgaaaccac tgcttcactt tttccgtcca
    36361 gagatcgcag atcagcaact ggaattctta ttcagccgtg cttctgtcaa tccaaataaa
    36421 ttgacattga tcctgatctc catggtagga acagtagcta taagcagctt gccaatatta
    36481 agcacgatga agaaaaaaga tcggatacaa atcgaaaaaa cagtaggaga tagtttttcg
    36541 attgcgttat tgattcttct tccttcattg actggaatgt ctttattagc tggaccacta
    36601 tacacattgt tttttggcta tgatcctgaa agtgtcggat atttccaaat ggctttgcta
    36661 gcttctttgt ttttctcttt attcacgatc ctatctacga tgcttcaatc tttgaatcac
    36721 catcgttttg cgatccgatt aactgtagaa gcaattatcc tgaaagtcat cttccaagta
    36781 atcggattag gattagttgg cggatacggg atgagcttat caaatggctt agcattcggt
    36841 attgtctttg ttcgcggcta tcactttatg tgcaaagaat accgaatagc acctttagca
    36901 aagatcagca attttttctt aaaaactttc cgctccaccc tgattatgct tgcagtatgt
    36961 tttgccgttt tctttttgct gaatcagcga ttgtcaatgg aatcaaaaag ctatgcaatg
    37021 atttattgtg tggctgtagg aagtattggc ggcttagtat ttttattttc tcaattcgga
    37081 aaaaatgggt ttcgaatgtt gaaaaatgtt aaacatcata gcagaagcaa agaataggtt
    37141 aactaatcgt tttttgctgt cacttgaaaa acggcaactc gtatgattac gcttgtcgtt
    37201 tttctatttt ccaattttag tttcatatct aatcttactt atgatatagt tataaggtct
    37261 ggaaaaattc tttgaaacga ggaaattaaa cacatgaaac ttgcagtagt tacagatagt
    37321 tcggcatatc tgccggaacg tatcaagaac catcccgact tattcgttat tccaatccct
    37381 ttgattatgg atgggaaaat ttataacgaa ggaatcgata tcgaagcgga tgaatattat
    37441 ggacttttaa aaaacagtaa agattttcct actacttcac aacctgtcgt aggggaagtt
    37501 ttgggtttat atgaggaatt gaaagagaaa gggtatgaca cgattttaag tatccatctt
    37561 tcttcaggga tttctggctt tgtcaacaca ttatttgcga tgaaagatga catcagcgga
    37621 gtaacggtca ttccttatga ctctaagatc actagtatgc cgatgggaca catggtagaa
    37681 gctgccttag acttaaatga tgaaggtcag tcccttgatg aaatacttgc acatatcgat
    37741 cgaatccgag ataataccta cgcttatctg attgtagatg atttgaacaa tttagtacga
    37801 ggaggacgtt tgacaaatgg tgcagcgctg attggcagct tattaaaaat caaaccgatc
    37861 ctgacatttt ctgaagggaa aattgtttta ttcgaaaaaa tccgttcaag taaaaaagca
    37921 tttgctcgag ctgaagaaat tattggtaga agaaataacg aaatacaacc gccagtcaaa
    37981 ctttacgtga tacatgcaaa taatttagaa gtagcgattg cggagaaaga gaaattgcag
    38041 aaaaaatatc caaatgcaga aatcgaaatt ggtcatttcg gaccagtcat tggtacacat
    38101 ttaggtgaaa aagccatcgg cattgccatt tcagcgcaat aattcctttt attcaaaaaa
    38161 cataccaaaa atattccaac atcatcttgg actttctaca tgttactaat gagcgtgtaa
    38221 aagaacgaga tggtgttttt atttctatca atgaagctct ttttctttgc aatcctcact
    38281 tcaatcctct ataatgtcgc atatagttta gtaaatgagt aaactactaa tttacttatt
    38341 tactaaaaat aaaaggatga ggagttaaaa taatggaaat accaacaaat ttaaaacata
    38401 aaccagtaat cgttgtagaa gactatgata aagttgatgg aagaaatgca ttaaatacgg
    38461 atgcaaaagg gctttcactg ggccttgctc agtggaatga tcgtggaaaa gtcgatatct
    38521 caggcaaggt atggcgacat actggagaaa aatggtcacg acagtcggaa gaattaccaa
    38581 tcacacgtat tttagattta gcgatcttag ctgcacaagg aagtttatac ttccaagatg
    38641 cttatcgtta tgaaaaattt tatgatccag aaaatccagt cgtagacatc attggattac
    38701 aagggaaccg aatgacggta gaagtagata ccaaaaatcc aaagatcgat gaagacatca
    38761 ttttgtatta cgatacacta caaaaagacg gagaactgat tggggaacga ttccgtattt
    38821 taaaacgtct tttagatgag ctaggatatt aatagacaga gatgatcaaa aggggaagag
    38881 aagcatggag aatttctcac taacagaaaa ccgaaccttt tcacggctag aaaagcaaat
    38941 gatctggaag aaaccgaaaa gccatcggac aagtgcagaa gaatggcgga tcgcctccga
    39001 aatcaaaggg aattggcaag atcctgaaat gaaaatcagt aacgtacttt tggaaggaga
    39061 tgccgggtcg gggaagacac aattagccaa agcactatct gctgatctgc aacttcccta
    39121 tacaaaagtg acctgttttg cagatatgga caaatcagat gttttcggag ccttattacc
    39181 tgtagtagat tctaataagg aacaagacca agaattacta gaagctattt accaaacaga
    39241 tacacttgaa gctgtactga cactgatcca gaaccattac ggcattgatc ctttttctgc
    39301 taaagaaaaa ttagcagagc tagttcaaag gatcgaagct gattatccag atgcaatcca
    39361 ttacagctat tacccttctg aaatcgttcg agcgattgaa aaaggatatt tattagagat
    39421 tcaagagccg actgtcatcc gagatgcctc tgttcttgtg gcacttaact cagcgctcga
    39481 accaaatggg atgttgaatt taccgacagg aatcattcgt cgccatccag attgcgtcat
    39541 tgtgatcact acaaatcgaa attaccaagg aaatcgccca ttaaatgaat ctttaagaga
    39601 tcggatgcaa catgcggaaa aaatggatct tcctgcctta gaagtcatgg cagaacgtgc
    39661 gatggcgaaa actatgatcc aaaaacaaga acttctctta aagatggcag agattatccg
    39721 tttgttggat gaaactgcaa aagctaacgc catcaaaggt gtagcaggaa tgcgttctta
    39781 tttttattgg gcaaatacct ataagcaagg acaagattta ctccagtcga tttatccaaa
    39841 agttttgtat aaattatcca ctgattcaga tgaattggca attcttgaac aagctttgtc
    39901 tgacagtgga ttgctactgg aacttcagga catattgaga aaagaaaaat ggggtcatcc
    39961 tcaatctgag catacaaaag gaagaaccat tagcgccgaa gaagcaaatg aacgaaacat
    40021 cactgaaaat gctgaagaaa ttctgcgctt agatgaaaag aaatcgttgt ctgctgaaga
    40081 accaaatgag ggagaagaga aacaagaaga aacaatagaa aaaaacgaga ttcctcctca
    40141 aatgcaaaaa gaacgcagta gcgatatcga aggaaaaaat caaaaagaac aacaaacagg
    40201 agatgattct caagaaatgt ctgcttctga catggaagca catgataagg aaatcaagaa
    40261 gcaactgaat aaagaagcgc gacaaatcat gaaggaaacg attcatgaaa aagaaggtct
    40321 catcgttcac cgaccagctt tccaaggaaa aacgccggaa gcacgtgagc tacacatgca
    40381 agtaatgcca atagtagaat cacttagccg gcaaatttta gagttactgg ataatgaaca
    40441 aacagagacg taccaaaaag gaaaatacga aggtcagcgg ttcaatgcaa gcaaagtagc
    40501 atatggtgat ttgagaaatt ttgacaaaaa gaacccgcca catgagcaac cttctttagc
    40561 ggtagctgta cggatcgatg aatctgggtc aatgatacgg gatgatcgga tcgaagcggc
    40621 aaaaaaagca gcgattgcca ttgccgaatt ttctaagaaa gtcgatatcc cattgttgat
    40681 ttacggagat acagcagacc gttcgtcaag agaaaagact tctttgtttt cttataaaga
    40741 atttgaagac ggatttcaat ggttaaatga aaaattagtc actatgaaac caaggcaaaa
    40801 caatcgtgat ggtgctgcac ttcgtttagc agcagaaaaa ttaaacagac aatccgcaac
    40861 aaccaaactg ttgcttaata ttagtgacgg tcatccaaaa gcgttgccgg attatacagg
    40921 caaaaaagca aaagaagata tccagtctgt tttgaaagaa tatgaacgtc aaggaatcct
    40981 atttgtctcc gcagctattg gccaagacaa agaagaaatc aagtcgatct acggtgaaag
    41041 tcgttttgta gatattactg acttgaatga atttcccaag caaatgattc aactgattgc
    41101 ccgctatcta tgataaaata aagctcaacg aacgcactta gcagattcgt tgagcttttc
    41161 gtttctagtt accggtaaca aggatacttc taaaatagaa tcggttataa tcaagaggga
    41221 ccgttaaagg agtgaaacga tatgatacaa gaacaaaaat ggtggaaaga agcagtaggc
    41281 tatcaaatct atcctgctag tttcaaagat agcaatggcg atggtcaagg agacatcaat
    41341 gggatccgtg aaaaacttaa ttatttgaaa gatcttggta tcggctttat ctggatcaat
    41401 ccgatctatc aatctccatt tgtcgataat ggttatgacg taagtgacta tcaagatata
    41461 gaagagagat tcggaacgat ggaagatttt gatttattgc taaaagaagc acatgaatta
    41521 gggatcaaag tgattatgga tcttgtcatc aaccatagtt cggatcagca tcaatggttt
    41581 gaagaatcga aaaaatctaa agaaagcccg tatcgcgatt attacatttg ggtcgacggg
    41641 gtagatggca aagaaccgaa taattggaca tcgattttcg gcggttctgc ttgggagtat
    41701 tctcatgaaa ctggacagta ttatctgcat gtttttgcaa aagaacaacc agacttaaat
    41761 tgggaaagcg agaaattgaa agaagaacta ttcaatatga tccgatggtg gttggataaa
    41821 gggatagatg gatttcgttt agatgcgatt tctcatgtaa aaaaagatga atattcagta
    41881 aaagccacag agaacccttt ctcacccttt caaaatgtct caggaatcga agaacatttg
    41941 accgatttga aacatgtttt tgaagagtac gatatcatga ctgtcggaga agcaagtggt
    42001 gtcactgcag aagaaggacc acaatgggta gggaaagacg gttatttcga tatgatattc
    42061 gaatttgatc atatccatat ctggcagcaa gaaaaagaag ggcaattaga tgtccttaaa
    42121 ttgaaacttg cattaagcgc ttggcaaact tcattggatg gtatcggatg gaacgcttta
    42181 tatatggaaa accatgatgt tcctcgtgcc gtttcagtgt ttggagatac tcgtcccgat
    42241 ttttgggcta tgtctgcaaa agcaatcgct atgatgtatt tctttttgca aggtacgcca
    42301 tttatttatc aaggacagga aatcggaatg acgaatatgc cctttgaatc gatcgatcaa
    42361 gttgatgcag tagattcgaa aagactttat aaaaggctgc ttgcggaagg taagacaaga
    42421 gaagaagcat tggatatcat tcgtgaaaca acgagagaca acagcaggac acccatgcaa
    42481 tggacttcgg aacaatatgc tggtttttct acacatgaac cttggctgat cactaatcca
    42541 aataccaaaa cgatcaatgt agaacaacaa gaatatgaac cagagtcggt cctgcaattc
    42601 tataagaaca tgatccgcat tagacaaacc aataaaggtc tgatatacgg ttcttataaa
    42661 gaatatcttc atgaacatcc acaactttat gtctatgaaa gatatttaga agatgaacaa
    42721 tatcttatta tggtaaactt aacagaatca cttgctgact atgaacttcc aaaagaagca
    42781 gatcagtcct ggacattact cttgtcaaat tcctctagcg gagaatttga agctaaaggc
    42841 atactagcac cttatgaagc tcggttatat aaaacaaaca agtaaaactt cctcgttaaa
    42901 gttcattagt tggactttgc gaggaagttt ttcagattgc tctgtcaatt actcatttca
    42961 ataattcgct ctaggaccac cgatatattt aggacgagag cgaagggctg tcacgtgagc
    43021 ttgtccaagg gttttcaaac gaggtctgac aggtacttgg acatgtttga tatgcatacc
    43081 gattgatgtg tcaccgatat cgataccggc ttgtccaact acgtgttcca cttcgacagg
    43141 atcattgaac tggtcaaaag cagcaacaga acaagcacct ccagcatgta gtgcaggaac
    43201 aacagagaca atttcgaaat tttttgcttc tgccactgtt cgttctacta ctaatgctcg
    43261 gttcaaatgt tcacaacctt ggacagctag cgcaatttct ttaggatcca acaactcttt
    43321 taacgtacgg atgatccatt gaccaacttc cgcactggaa ttttttccaa tatgtcctcc
    43381 aacgacttcg cttgtgctgc atcctaaaac aaaaagatca ccttttttca agtgtgcctc
    43441 agccaatatg tcattaacta tttcagtcaa ttggtctttt aattcttttt ctgacaactt
    43501 cattttctaa aaccttcttt ttcaattaat attgcttccg tgcttgaata cgttgaagac
    43561 ttgcagttat aggaaaggca agtcccattc caatcagatt ttggaagatg tttcctggta
    43621 tagaagccac tccagccggc caatcatata aaatccaacc ggcgatacca tagccgatga
    43681 tcataactaa gcttcctaat aaaagcccta atccccacat acgagtagaa gatttgctga
    43741 aagaaccagc aacatatcct tgtaacccgt ggatcactaa tgaaaaaact gcccactgcg
    43801 gatatcctga aatcaaatcg atcaatagac cactggaagc accaacaact aatccacccg
    43861 ttggaccata aagaaaagca gcggtataga tcccggcctc gcataatgtc acaaatccat
    43921 tcgtagccgg tacagggatc aaaattgtta atgaaagggc aactgtcaac gcaatcagca
    43981 tagcatagat cgttaattgc ttagttttca tttctcattc ctcctttttg aataccgcca
    44041 gaccagacac ttccggtatg atcgttcatc agcacgccat tagaaataca atgggcaaca
    44101 aattttttac tttctgctac tgctttggta aaatctgccc ctaacacaag attcgctgtt
    44161 attgcagaag aaaaggcaca accggccccg tttactgttg tagtgtcgat ttttttatga
    44221 gaaaatacct cataatgatc aattgaatag agaagatcca cagcttcatc tccagccatc
    44281 cttgtgccgc ctttgatcac aatgtttttt gttcctgaag cagtgagttc tttagcgaga
    44341 tggatcattt ctgttaacga agagggaaga gcttgaccag aaagtaaagc agcttctgcc
    44401 aaattaggcg taatcatcgt aacaagtgga aaaagttctt cgatgagctg cgaaatatac
    44461 aattgattga tcacagcttc agtttctttg aatgccaaaa cagggtctaa aatgattggg
    44521 atattttgtt ttgtttttat gaagtctcga acaaccatga ttgcttcact tgaattcaat
    44581 aacccaattt tgataccatc taatgaagtc attttatcaa tcgaaactaa ctgtcgttta
    44641 agcaattcca aagatataga ttccagcata aatcgctcat taatatctag tgcccctata
    44701 gaagtcaagg cgcttagtcc gaatagacca aaattctcaa aagtttttaa atctgtttgg
    44761 attcctccac cagcaaatgg atcagaaccg ccaattgtca agattctttt cataacattt
    44821 tcctccatga ataagagtat aacgaaattt tcaaaaaaga aaaacagcca attggcatat
    44881 ttttatctca tccaatttaa aaaaacaaaa agaaaagaaa gaccaaaatg gatctttctt
    44941 tccttaaata gttaggactt ttgtgatttt aattctttct cgatttgaag ccgttgcact
    45001 ttcattgtag ctgttcgcgg gattgcatca aaatcacgga tgatagggac gttcaagcga
    45061 ggaagttcat ggacttgctc ccaccatcga ttccaatcca tttctttatc aggagctaaa
    45121 gcaataatcg gttgtggaga atgattttta tcccttacaa tcactacttc tgccaaaaaa
    45181 tctaacgaat ctaataaaaa gtcttcaata gctaatgtac tattgatcgt ttcgatcaaa
    45241 tccacttgcc gatctttcaa aaataggtgg ccatgcttat ccataaaacc gtaatctccg
    45301 ctatcccacc aatcgccata aacattttcc tggaaccgtg catcttcctt gtaataagtc
    45361 aaagcccgtc ctttagacag taattgtata tgaccatctg tgttttcagg taggacattc
    45421 ccaactgaat ctgtaatccg agcgcttgtc atgtcttcca gtccaacgcc catatctctt
    45481 gcatcacttg ttttcaaact ctctagtgta tgagccttaa gaatcattgg tccgcattca
    45541 ctttggccat atacttgaag aaataccgca tcctgtgcca tcgacgttcg caaaaatgtc
    45601 ttcattgtct ggttgtttat agcatcaaaa gtggagtgat agtatcggat acccgaaaaa
    45661 gcttctggat gctccttagc agtaaaacgc cactgaacaa agttattcgg atgggtctct
    45721 agtgcaattg gccggtgagc ttccaacata tgaacaactt ttgaactttg tgcgtttgct
    45781 aaaggcatca taggaaatcc catggacatc aaagaagaga taccaatatt gaatctggaa
    45841 tgcactggag agatgtgaaa agcgattaat ttcttttccg aaatttttgt gaaaactgtt
    45901 ttttgccatt tcgtccgcca tcccatagaa tgagcagaat gacaaataag tttagggata
    45961 ccagttgtac cagaagtatg ggtcatataa gaaatttcat ttttgtctaa aaatgattga
    46021 gaaacagaca aagcaggttg ttccattaaa taaagaatag gaa
//
LOCUS       DAZAOD010000013        35267 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000013 DAZAOD010000000
VERSION     DAZAOD010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.014"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            61..1026
                     /locus_tag="ACHDPO_000791"
     CDS             61..1026
                     /locus_tag="ACHDPO_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFN3368437.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(1083..1313)
                     /locus_tag="ACHDPO_000792"
     CDS             complement(1083..1313)
                     /locus_tag="ACHDPO_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFN3368438.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(1399..2286)
                     /locus_tag="ACHDPO_000793"
     CDS             complement(1399..2286)
                     /locus_tag="ACHDPO_000793"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFN3368439.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(2375..3598)
                     /locus_tag="ACHDPO_000794"
     CDS             complement(2375..3598)
                     /locus_tag="ACHDPO_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFN3368440.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(3615..4661)
                     /locus_tag="ACHDPO_000795"
     CDS             complement(3615..4661)
                     /locus_tag="ACHDPO_000795"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFN3368441.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(4825..6552)
                     /gene="ptsP"
                     /locus_tag="ACHDPO_000796"
     CDS             complement(4825..6552)
                     /gene="ptsP"
                     /locus_tag="ACHDPO_000796"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFN3368442.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(6552..6818)
                     /locus_tag="ACHDPO_000797"
     CDS             complement(6552..6818)
                     /locus_tag="ACHDPO_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFN3368443.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            7297..9531
                     /locus_tag="ACHDPO_000798"
     CDS             7297..9531
                     /locus_tag="ACHDPO_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3368444.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            9679..9999
                     /locus_tag="ACHDPO_000799"
     CDS             9679..9999
                     /locus_tag="ACHDPO_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFN3368445.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(10204..10428)
                     /locus_tag="ACHDPO_000800"
     CDS             complement(10204..10428)
                     /locus_tag="ACHDPO_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFN3368446.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(10626..12206)
                     /locus_tag="ACHDPO_000801"
     CDS             complement(10626..12206)
                     /locus_tag="ACHDPO_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFN3368447.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(12607..13983)
                     /locus_tag="ACHDPO_000802"
     CDS             complement(12607..13983)
                     /locus_tag="ACHDPO_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFN3368448.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(14111..15199)
                     /locus_tag="ACHDPO_000803"
     CDS             complement(14111..15199)
                     /locus_tag="ACHDPO_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFN3368449.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            15371..15805
                     /locus_tag="ACHDPO_000804"
     CDS             15371..15805
                     /locus_tag="ACHDPO_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368450.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(15883..16416)
                     /locus_tag="ACHDPO_000805"
     CDS             complement(15883..16416)
                     /locus_tag="ACHDPO_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFN3368451.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(16510..17688)
                     /gene="mutY"
                     /locus_tag="ACHDPO_000806"
     CDS             complement(16510..17688)
                     /gene="mutY"
                     /locus_tag="ACHDPO_000806"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFN3368452.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(17681..18478)
                     /gene="recX"
                     /locus_tag="ACHDPO_000807"
     CDS             complement(17681..18478)
                     /gene="recX"
                     /locus_tag="ACHDPO_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFN3368453.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            18585..19967
                     /gene="rlmD"
                     /locus_tag="ACHDPO_000808"
     CDS             18585..19967
                     /gene="rlmD"
                     /locus_tag="ACHDPO_000808"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFN3368454.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(20141..20719)
                     /locus_tag="ACHDPO_000809"
     CDS             complement(20141..20719)
                     /locus_tag="ACHDPO_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFN3368455.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            21041..21511
                     /locus_tag="ACHDPO_000810"
     CDS             21041..21511
                     /locus_tag="ACHDPO_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFN3368456.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(21619..22845)
                     /locus_tag="ACHDPO_000811"
     CDS             complement(21619..22845)
                     /locus_tag="ACHDPO_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFN3368457.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(23599..23799)
                     /locus_tag="ACHDPO_000812"
     CDS             complement(23599..23799)
                     /locus_tag="ACHDPO_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFN3368458.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(23933..24541)
                     /locus_tag="ACHDPO_000813"
     CDS             complement(23933..24541)
                     /locus_tag="ACHDPO_000813"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFN3368459.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(24626..25096)
                     /locus_tag="ACHDPO_000814"
     CDS             complement(24626..25096)
                     /locus_tag="ACHDPO_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFN3368460.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(25144..26058)
                     /locus_tag="ACHDPO_000815"
     CDS             complement(25144..26058)
                     /locus_tag="ACHDPO_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFN3368461.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            26204..27007
                     /locus_tag="ACHDPO_000816"
     CDS             26204..27007
                     /locus_tag="ACHDPO_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFN3368462.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            27185..28132
                     /locus_tag="ACHDPO_000817"
     CDS             27185..28132
                     /locus_tag="ACHDPO_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFN3368463.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(28200..28493)
                     /locus_tag="ACHDPO_000818"
     CDS             complement(28200..28493)
                     /locus_tag="ACHDPO_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFN3368464.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(28521..29186)
                     /locus_tag="ACHDPO_000819"
     CDS             complement(28521..29186)
                     /locus_tag="ACHDPO_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFN3368465.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(29326..29958)
                     /locus_tag="ACHDPO_000820"
     CDS             complement(29326..29958)
                     /locus_tag="ACHDPO_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFN3368466.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(29965..31032)
                     /gene="liaS"
                     /locus_tag="ACHDPO_000821"
     CDS             complement(29965..31032)
                     /gene="liaS"
                     /locus_tag="ACHDPO_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFN3368467.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(31029..31760)
                     /gene="liaF"
                     /locus_tag="ACHDPO_000822"
     CDS             complement(31029..31760)
                     /gene="liaF"
                     /locus_tag="ACHDPO_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFN3368468.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(31929..32408)
                     /gene="greA"
                     /locus_tag="ACHDPO_000823"
     CDS             complement(31929..32408)
                     /gene="greA"
                     /locus_tag="ACHDPO_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFN3368469.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(32544..33719)
                     /gene="mltG"
                     /locus_tag="ACHDPO_000824"
     CDS             complement(32544..33719)
                     /gene="mltG"
                     /locus_tag="ACHDPO_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFN3368470.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            33923..35092
                     /locus_tag="ACHDPO_000825"
     CDS             33923..35092
                     /locus_tag="ACHDPO_000825"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFN3368471.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT        10614 a         7118 c         5840 g        11695 t
ORIGIN      
        1 cttgtccatt atttcaaaat ttgttatagt ctttttattc aaagcgtaaa aggagatcct
       61 atgttaaaag aaaaaatgaa aactctcccc atgctgccgg gtgtctatct tatgaaagac
      121 cgagatggta aggtcatcta tgttggtaaa gcaaaacggc tcaaaaatag agtaagcagc
      181 tattttcatc agaataaaca gcattcaaaa aaagtattac gtatgattca tcatataaca
      241 gattttgatt tcgtcgtagt agacacggaa ttagatgctt tattgctcga gtgtcaattg
      301 atccaacatt accgtccttt ttataaccga caaatgaatt atttcagtaa ttataattat
      361 gtacatatta ccaataaggg atttgtatta acagatactc ctacggctcg aacatacggg
      421 ccttttcgtc tctataaaaa aatgccgtct attttgcgta taatggaaga aacttatcaa
      481 atgccttggt tgtctgaaat tagtttgtta gctttgcgag tccagcttcc tgacctacag
      541 gaaatgactt ttgaacagaa aaaaaaggaa ctccaagggc tgtttcaagg ccgaaataaa
      601 aagctactga cttacttgaa aaaaagacaa caacatttca tctatcagtt gaatttcgaa
      661 aaagccggta tgcttcaaaa agatatcgaa ttagttactt attttattag acggatccag
      721 gaacaaaagc agtttttaag aacaccatcg ctcaccttca gcatgccatt agcagcagat
      781 gagagtcaga aaaagcacta cctcgtttgt tatggtcaac ttgcagaaac aatgattacc
      841 tctggtgacg tttctcctga cttctattat gaaaagaaag aagctcattt atctttgaaa
      901 cgtcaattgt caaaagaaga aatcgatcct gtacaaatct tgatcagtta ccgcaaaaaa
      961 ttagaaaaag aacagtttga aattgaactg ttaaacaaaa aagaagctga aaagcaacta
     1021 aattagttgc ttctcggctt cttttaggca tcttcaactt caaatgtcaa ttatcctaaa
     1081 atttattgga ttaagtcata gatttccatc gctacgatat cgatattatc aaattcgtat
     1141 tgctgatgag tatctgtttc agttaattca aatgtatcgg tcgctttatc ataagttact
     1201 gtacacttct ctacgccttc tttttcaaaa cggcgaactt gcagttcatt atctgctgac
     1261 tcgaccatag cctccagtcg ttttatgatt gcgactaatt gtgaatgtgt catcggaggt
     1321 cctccttttc ttatttctgt tatattgtat caaaagcata gcctacttgc attgattttc
     1381 tctaaaaaaa ctcgtttttt atgatttttt ttctggtatt tttccttcag gccaccaaag
     1441 tttgatcaaa gcttgggttc cgtcattctc aaaaccttta tctgccaact cttcatatag
     1501 tttcaatgct tgggtagttg ctggcaatac aagatccatt ttttctgctt cttctaatgc
     1561 aatctttaaa tctttgataa aatgtttgac aaaaaaacca ggtgtgtaat cttcttttaa
     1621 aatacgagga gaataattgc ttaaagacca gttagctgca cttccacctg aaagcgtctc
     1681 aatcactttc tttaaatcaa gtccgttttt ttgtgcatag acaagcattt ccgtcattcc
     1741 tgtcatcgta cctgcaatca tgatctgatt agccattttt gtatgctgac ctttcccagc
     1801 agaaccatgc aatgtaaatg tcgtaccaaa ttctttgaat aaaggcagta cttgatcata
     1861 aacggcttct tctccaccga ccatgatcgt cagtgtacca ttctttgctc ctaagtcacc
     1921 accggatacc ggtgcatcta acgcatctgc gcctttttct tttgctgttt ttgcaatttt
     1981 ttctgccagg cttggtgtac ttgtagtcaa atcaactaaa atatgtcctg agatatctgc
     2041 agaaaaaatc cccgactgtc catagtagat ttcttctaca tctttggggt aacctaccat
     2101 tgtaaagaga atattacttt gttctgctac cgcttttggt gtatctgccc agatagctcc
     2161 ttctgttact aaaggatcag cttttgcttt tgtccgatta tagacagcta cttcgtgtcc
     2221 tgcttctagt agatggcgtg cgacagcact tcccatgacg cctgttccga taaaaccaag
     2281 tttcattttt tcgacctcct aaaaatcaaa aatccttgct tctatgctag tatacgctag
     2341 aaacaaggat tttttcataa aaaatgtttg aattttatct tttaaatgaa tttaatttta
     2401 ttttgattcg ttcaatcgag tcttcttctt cttttcttcg catctcttct tcatgataaa
     2461 caaccatgtc ttgataaaat tcgatcatag cttcgccgaa atgtgtagat gaaatatcat
     2521 aaagtttagc ttctaaaact tttggatctt taggaacttc actggaaata taatcaataa
     2581 gtgctggtgc aaagtcttcg tcggtttcaa aagttttccc taatgaagga tgatcgaaca
     2641 atcggttcaa ataagcattt ccttccacga cacaaggtgt tccggctgcc atcgcttctg
     2701 tataagtaag cccttgtgtt tctgaagtag aagcactgac aaaataatct gccgctttat
     2761 aataaagtgc tacatcattg ttgtccactt ctcctgtgaa ctgcacaaat tcttctaact
     2821 gcagttctga gatcaattcc tctaactctt ctacataagg tccttttcct acgataacta
     2881 atctggcgtt aggataagcg gagatgacct gaggaaaccc attaatcaag gcttggatat
     2941 ttttctcata agaaatcctg cttaaagaaa gaatcatcaa atggttttcc tgaagaccta
     3001 gtgactccct taatttgctg atatcctgct gagtgatatc agaacgtttg aatttttcaa
     3061 tgtcgatacc agtaggaatc acgcgaagcg gtgctattac accatagctg cgtaatgtat
     3121 caataacacg ttcacttgga caaactacac ctgtcgtatg atttgcaaat aatctagaca
     3181 agtattttac atgggattgc ctgatcactt ttcctttacc gatataatga aggtagtctt
     3241 catacatcgt atggtaagta tggatcagag gtattttcaa cttcttagct accatcttcc
     3301 caagtatccc tgctccgaat tctgtatggg tatgaataag atctagttct agttctttgg
     3361 caaccaaata agcataccac atgcctctaa caacaactct tcgatccttg aaagaaataa
     3421 atggtacact tggcattcga atcacatctt tttccaactt atccgcatta ggatcggtcg
     3481 ttgtaaaaat atagacttca tgcccatgtc tttctaattc ttgttttaat gttttgatcg
     3541 atgtagcaac tccgctgact tgcggaaagt aggtatcggt aaaaaagccg attttcatgt
     3601 ttttcgcctc caaactagtc cttgacctga tttacttttt ttaatttgct agagactttt
     3661 tcattcagta cactttcgta tacattttta agttcttcac cgattttatt gatacttcgc
     3721 tcttttgctg tttgataacc ggcttgtgtc gtactcggta gttcttgatt ggtaatctgt
     3781 tggatcagtc ggataaattc ttcgtttgtc ttccccatat agcagttctt gctatcttct
     3841 aaccagccat tatacactgg aatatctcga acaagtacgt tttgtttgct tgctaaagct
     3901 tctaaaacaa cgatcccttc tgtctcttca taagaaggga aaaagaatag atctgcacct
     3961 gaatacgcac cttctatgat ctctccacga atgtaaccag gaaacaggac attttcagga
     4021 tgatcttctt ttacaatttt ccggatgttc cgaggaatcg agtacatggg aacatgacca
     4081 aaccaaataa atgtgtattc gggcatcttc ttagcaattt ctacgaaatc aatgattcct
     4141 ttacgttcga aaaacaaacc gacacaaatg attacttttt gatccggaga cagtttgaaa
     4201 tattctctga acttttgttc tttcattgga tcagggtgat atttctctaa gtcgatccca
     4261 ttggaaatag cttgaatcgg cacacggata ccatagcttt ccaacaactg ttttgaataa
     4321 ggtgttggcg tgatcagata gtccgctttt tggtacaatc ctaccagata tttttttacg
     4381 ataggagaaa gctggttcga tctgataaag gaatttcgga aatcttcctc tgtagaatgc
     4441 gcatgataga caactttttt tccttctctt ctggctttat tgaccatatt atgactattg
     4501 attccgtatg tattgatgtg caggatgtca taatcttctt tttcatctag tgtataagag
     4561 ataccgactt ccgtcagagc acgtttttga tgatcaagcg cacgcccgat tccagatttt
     4621 gcaagcatct tttcactttc aaaatataat aataccttca ccttacgtcc cccttcactt
     4681 atatagtata acatagccta caaactgtca ctcaaactta agccctattt ttgtctattc
     4741 ttactgacaa aaacgttttc ttaaaaaaga acaaaaaaac tggcgtagct cttttacaag
     4801 ccacaccagc ttttgatacg ttgtttattt tacatattca tgaacaagtt caacgacttc
     4861 ttccatcata tcgcattctt tcaatgcacg atcagcaagt tcagccattt tcgctgtgtc
     4921 caagcgtttc attaaactac gcgttttaag aatagatgtc gcactcattg agaactcatc
     4981 tagacccata cctactagca atggaacagc tgtttgatct ccagccattt ctccacacat
     5041 acctgcccat tttccttcag cgtgtgctgc atcaattaca tttttgatca aacgtaaaat
     5101 tgatgggtta tatggttggt acaagtaaga aacgcgttcg ttcatacggt ctgctgccat
     5161 tgtgtattga atcaaatcgt tcgtacctac agagaagaaa tctacttctt ttgcaaactt
     5221 gtctgctaag actgctgctg ctggaatctc gatcatgatg ccgacttgga tcgtatcaga
     5281 tacttccttg ccttcactta tcaatttttg tttttcttct tcaaagatcg cttttgctgc
     5341 gcggaattct ttgagtgtag ctaccatagg gaacatgata cgtaaattac catgaacaga
     5401 tgcacgaagc aatgcacgca tttgtgtacg gaacatttcg tcgccttgtt cagataaact
     5461 gatacgcaat gcacgatatc ctaagaatgg attcatttca tgaggtaatt gcagatatgg
     5521 tagttcttta tctccaccga tgtccattgt acgaacaact acaggttttc cttccatacc
     5581 ttctaataca gctttgtaag cttcatattg gtcatcttct gttgggaagt ctggagaatc
     5641 catatacagg aattcagtac ggtacagacc aactgcttct ccaccattat tatggacacc
     5701 aactagatct tttggtgttc cgatgtttgc agctaattca aaatgcttgc cgtcagctgt
     5761 gacagtttct gcatttttta atttttccca ttctgctttt tgtgctgcgt aatctgcacc
     5821 tgctttttca aattcagctt tttgttcatc tgtaggatcg atgattacat cgccttcgat
     5881 cccgttgaca gccaaaatat cgccttcttt gactttagca gtaatttctt ttgtcccaac
     5941 gattgctgga atttctaaag aacgtgccat gatagcagaa tgtgaagtac gtccaccaat
     6001 gtctgttaca aacgctttta caaaattgcg atctaattgt gctgtatcac ttggagtcaa
     6061 gtcatgtgca acaacgacca cttcttcgtt gatcattgat ggatttggta aagtaacgcc
     6121 taataagtgc gctaaaatac gtttagcaac gtcacgaata tctgcagcac gctcttgcat
     6181 ataagcatta tcttccattg cttcgaacat accgatatac atatccgtta cttcttttag
     6241 cgctgattca gcatttacgc tgttgtcttt aatattttgc ttgatttgac ctaccatttc
     6301 tggatctgaa agaaccatca aatgggcatc aaatacttgc gcttctgctt cacctaagct
     6361 ttgcgctgct ttttcacgaa tttgctgcaa ttcttcagta gatttagcta atgcagcatc
     6421 caaacgagct tcttcagccg cagtatcttc tactgttgcc ttactgaatg ttaaatccgg
     6481 ttgaactagc aggtaagctt ttgcaacggc tacaccgtca ctagcggcaa tcccttttag
     6541 catttcaacc attattcaga taagccttct ttcttcattg tttcaacgat tgctgccatt
     6601 gcatcagctt cgtcagcacc ttctgcagta atagtaacat cagaaccttg acctacacct
     6661 aaagacataa cgcccatgat tgatttcaag tttactgatt tacctttata ctctaagttt
     6721 acatcagagt taaatttgct tgctgtttgt actaatagtg tagctggacg agcgtggatc
     6781 ccagtttctg ctactacgtg aaattctttc ttttccatat taatcggtct cctttaagtg
     6841 agtgttgttt ttatgtgagg gttttctttt ttagtaattc agagaatcct aacaaatgcc
     6901 accctttcat ctgtaaagat taacattttt tttcgttaga tacaacagtt ttcattcaat
     6961 ttcagataaa agtattcaaa ttattccgga ttctttttca tccttttctt cacattttat
     7021 aacaaacgtg tttatttcct ttttcttgtc gctttctctt ctcctgacgt ttatcattct
     7081 ttcctttgac cctctttgtt ttcatatgaa acgaattact tgcttccctt tttattttta
     7141 gtataataag agtcaaaggt caggaatggt caatagagat ttcacctttt ctacctcata
     7201 aatctcttaa aaaactaggg gttattcttt tacctcatga aaaacgagat gtaaaatatg
     7261 gatgtaccca tttttgtgaa aggacgtgaa tgattcatgc tttgtcaaaa ctgcggcaag
     7321 aatgaggcaa cgattcactt gtatgccact gtcaatggtc agcggacaca actcgattac
     7381 tgtcagagct gttatcaaaa aatcaaaaat caacaaaatg gaggtctgac taatatggcc
     7441 caaaatgatc catttggatt tggcagtttg gacgatcttt tccgttccat gtctcgccaa
     7501 atgcaacagc aaggaaatta tgagcaaaca ccaccaacac aatttggcgg aaacaacaac
     7561 ttcaatggtg gtcagccacc tcaaggcaat acagaaggtt tattgggaga atacggaatc
     7621 aatatcacag aacaagcacg acaaggtgat atcgatcctg tgatcggacg cgatgacgaa
     7681 atcaaacgag tcattgaaat tttaaatcgc cgaaccaaga acaatcctgt cttgattgga
     7741 gaaccaggtg ttggtaaaac agcagttgtt gaaggtttag cacaaaaaat cgtagatggt
     7801 gatgtaccgc aaaaattaat ggacaaagaa gtcattcgtt tagatgtcgt atctttagtc
     7861 caaggtactg gtatacgagg acaatttgaa gaacgtatgc aaaaattgat tgaagagatc
     7921 cgtcaagcag aaaatgtgat cctattcata gatgaagttc acgaaatcgt cggtgctggt
     7981 tctgctggtg atggaaatat ggatgctggt aatattttaa aaccagcttt agctcgagga
     8041 gaattgcaaa tggttggtgc tactacctta aatgagtacc gcatcatcga aaaagacgct
     8101 gctttagaac gtcgtatgca acctgtacgg gtagatgaac caactgtcga agaaacgatc
     8161 agtattttga aaggtttgca aaaacgttat gaagactatc atcatgtaaa atatactgat
     8221 gaggccatcg aagcagccgc aactttatcc aatcgttacg tccaagatcg cttcttgccg
     8281 gataaagcca tcgatttgct agatgaaaca ggttctaaga aaaacttgac gatccaaatc
     8341 gttgatccta aaacaatcga gaaaaaactg caagaagcag aagaacaaaa agttttagct
     8401 tctcgagaag aagatttcga aaaagcagct tattatcgcg atcagatcaa taaacttcaa
     8461 aaaatgaaag aacgtcagct cactgaagag gaaacacctg tgattaccga aaaagatatg
     8521 gaaaaaatcg ttgaacaacg gacaggtatt ccagtgggtg aattaaaaga aaaagaacag
     8581 acacaactga aaaacttagc agatgacttg aaagctcatg tcatcggaca agataacgct
     8641 gtagatcgag tagcgaaagc gattcgccga aaccgtgttg gattaaacaa acagaatcgt
     8701 ccaatcggct ccttcttatt tgttggacca actggtgtag gtaaaacaga gcttgcgaaa
     8761 caacttgcct acgaactatt cggttcacaa gattcaatga ttcgtttcga tatgtctgaa
     8821 tatatggaaa aacatagtgt ctctaaattg attggttctc ctccaggtta tgtcggatac
     8881 gaagaagctg gtcaattaac agaaaaagta cggagaaatc cttacagtct tgtcttgtta
     8941 gatgaagtag aaaaagctca tccagatgtt ttgcatatgt tcttgcaaat cttagatgat
     9001 ggtcgattga cagatgcaca aggaagaacg gtcagcttta aagatacgat catcattatg
     9061 acaagtaatg ccggaactgg taaagtagaa gcaaacgttg gttttggtgc ggcacgcgaa
     9121 ggtgttactc gttctgtatt gaaccaatta aacaactact ttacaccaga atttctgaac
     9181 cgttttgacg ggatcatcga attcagtgca ttatcaaaag aaaacttgat gacaatcgtc
     9241 acactaatgc tagacgatgt caaccaaatg ctggcagcac agcaacttca catcgaagtt
     9301 cctacgaatg tcaaagaaaa attagttgac ttaggctatg atccatctat gggtgctcgt
     9361 cctcttcgac gcacgatcca agaacaaatc gaagatggta tcgctgaatt ttatcttgat
     9421 cacccttcta tccatgagtt gaaagcaaaa ctggataaag atggaaaaat catcgttact
     9481 tctaaaccag aacgtttggc taaagaatca gccgaagaaa cggctgaata aatccagttt
     9541 tatagcgtga gacggtattt ctttgagaaa tgccgtctca ttcttttttc agaaaagtca
     9601 aaatactgtt cattttataa aaaagaaatt ataataagag aaacaagcaa ttaaaaatac
     9661 ataaaagagg tgagcgccat gaaattggta aatgtaacaa acagccattc ccgtcttgta
     9721 ttaaaccagc ttgaaaacac tgatgcccat ctagtcaagg tctacacagc cggaaatacc
     9781 actattgtct acactgaagc ccctgaacat aatgaaattc tgctgatcaa tgacaaacgt
     9841 aaaatccagc cgaaagaaat cgaagatgct aaaaattatt tcttagataa aatcaaagac
     9901 gccgtttacc acgaggatga aatcaaagta atcgaattgg caggccttgt tgaaatctcg
     9961 attccaaaac atgaattagg cgctacatta gccgtgtaaa caaattttga acataataat
    10021 taaagagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac
    10081 ggcgaaagca gaagcaactc cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa
    10141 atttttgtga attccagctt atttcttgga gttaaacgct tctgtctcag cctctttttc
    10201 tttctagctt tttgattttt ctcttttctt ttgtactttt ctcttttcat tttcagttct
    10261 acgcgtgtct ttatttttaa ctttttcctc tttatggatg attgatcgta ctttttgtgc
    10321 aatttgctcg tttttgtccc agtcttttac atctaataat cgacataatc gtaacatctc
    10381 ttcttttttc tgtttttttc tttcacgtct ttgccattct gtttccatgt gtcacactct
    10441 cctttcttta atcatatgta cgcaaaataa tttttatatt tttttgatta gacatttcta
    10501 tgattttaat atagtaaaaa gagccgtcac ggaaaatccg tcacggctct aaacaaaata
    10561 tgagaggctg tttttgtttg gctattctta ttacttgatg cagggcagct tgtgtcaaga
    10621 cttctttaca tcaaactttt taattttaca ttgggatatt tatccgcaaa ccagcgttct
    10681 gcaaattggt tctcgaataa gaacaacggt tggtcgaaac ggtcacgagc caagatattg
    10741 cgacttgaac tcatcttctc atccaaatct tctggatcga tccagcgagc gattttgtgt
    10801 cccattggag acatgattac ttcggcgtta tactcattta acatacgata ttggaatact
    10861 tcgaattgta gctgaccaac agctccaatg atatattctt ccgttagata tgttttataa
    10921 agctgaatcg ctccttcttg aactaattga tagattcctt tgtggaagga tttttgtttc
    10981 atgacatttt ttgcagtcac tttcataaac agctctggag taaatgaagg gagttcttca
    11041 taagcaactt ttagttttcc ttcgaacaat gtatccccaa tctgataatt gcctgtatca
    11101 tatacaccga tgatatcgcc tgctactgct ttttcgacgt tttctctcga atctgccata
    11161 aattgtgtga cattgcttaa tttcagtttt ttatttgtac gttccaacca gacatccatt
    11221 cctcgttcga atgttccaga acagattcgg acaaaagcga ttcggtcacg atgggctgga
    11281 ttcatatttg cttggatctt gaatacgaaa cctgaaaatt cttcctcata aggacttacc
    11341 atctgatcat cttgtgtttt gtgtccataa ggagctggtg ccaattcaac gaaagtctct
    11401 aaaaaagtct gtacaccgaa gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg
    11461 ccacgagcaa ttttttcttg attaaatgca tctccagcct ctttgattag ttctacttct
    11521 tctaagactt gttcatataa ggaattttca gttagaggat gattttcggg aagcagtcca
    11581 tcttcatcca attctactaa tcgttcatcc tgataatttt ccggacgata aaactctaca
    11641 cgattatggt agatatcata aagaccttct agccctttac ccataccgat tggccaattc
    11701 atcggataag attcgatatc taatagctct tctaattctt ctaacaattc caatggttca
    11761 cgaccatcac gatctagttt gttgataaaa gtaaatatcg ggatgccacg tttttttaca
    11821 acttggaata atttctttgt ctgtgcttcg atcccttttg cactatcgat taccatgacc
    11881 gcactatcca cggccatcaa agtacgataa gtatcttcag aaaaatcttc atgtcctggt
    11941 gtatccaaga tatttactcg tttcccttga taatcaaact gcataacaga actagtaaca
    12001 gaaatcccac gttgtttctc gatttccatc cagtctgatt tggcaaaatt acctgttttt
    12061 ttgcctttta cggtcccggc ttgacggata gccccaccaa acaatagtaa ttgttctgta
    12121 atcgttgttt tcccagcatc cggatgggaa atgatcgcaa aagttctgcg attgtccact
    12181 tgttgcttta attttggatt attcataacc taactccatt tcttccattc aattatttat
    12241 attttctcta ggcacagatt gtccgatctc ttaaagaaag acaatttcat atagggctgt
    12301 gacaaaagcc gtgtagcagt ctctttttcc gagtaaacgg cgttctagag acagcctatc
    12361 agcaataagc ccacccaagc caaaaatacg aaaagctgtt tttgcttggc tgctcttatt
    12421 acttaatgca ggatagcttt ttcacaacct ttgtcaacta ctacaactga atcagtatag
    12481 catggattca gcgaatgaaa aagccaccaa accataagag tcaaatattt ttttgtcagc
    12541 tgactaaaag aaaagacgtg ttgcttgttt attcaagcaa cacgtctttc ataaccaagt
    12601 ttccaattat cttcttggct cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc
    12661 ttcaggttcc gcttctgttt cttccggatc atgaaaaatg acacggattt taaggattcg
    12721 agaaccttcc atttcttcag aaaccagcgt aatattatcg acatcaaacg ataacttttc
    12781 gccttcatcc ggaatcatgc ctaatgctgt aatcaaataa ccagccatcg tatctacatc
    12841 actcatatgc agatcactgt caaaagcttc attgaactca tcaatcagca tacgtccttg
    12901 gatgatatat tcgtgttcat cgattttttc ataaagattc tcaacttcat ctgattcatc
    12961 atcgatttct ccgacgattt cttctaaaag gtcttctagt gttgctaacc caacgacgcc
    13021 gccatattca tctaataaaa tagccatctg attctgcgtc tttttcattt catataacag
    13081 atcatcaata aagaccgttt caggaacgaa taaaggctcc tgcatgattt tcttgatatc
    13141 taaattatca aagccgaatt tatgggcagc ttttagtaaa ttctttgtat gaaggattcc
    13201 gactacttta tctttgtctt cgttataaac agggattctt gaatagtttt cggataaaac
    13261 ttcattcaca ttttcttcca cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg
    13321 gaccatgact tctcgggcaa ctttcgtatc aagagaaaaa accccttgga gcatttctaa
    13381 ttcttcatta ttcaatacgc cttcgttttc aagcatataa cgcatttcat ctctggtcat
    13441 ttttgaatct tcatcatcaa aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc
    13501 agaaagcagc cagacgaagg gcttagctac tacaccaatc aagcgtatca gccctgaagt
    13561 gaactttgcg acttcttctg atttatttaa agcaatacgt ttagggtaca attctccaaa
    13621 aacaatcgat acataggtca aaatagccag cacaatgata tttgcaatat tttttgccgc
    13681 tgtgccgcca cctaataccg gagctaaccg ttccgataaa gtattagcta gtgaagcacc
    13741 agacaaaatg ttgaccaaag tgattcctac ttggattgtc gataggaaat tatttggatt
    13801 ctgcaatatt tttaaaagct tttgagattt cacatctcct tcatcagctt tttgctcgat
    13861 tcgattctta ttgatcgaaa caacagcaat ttcggaagct gctaaaaaag cattgatcaa
    13921 tgtcaaaacg atcaataata aaatctgcgc taacagcgac tgactctcag ggtcagcatt
    13981 cataatcgca ttctctcctt ataaaattaa tttttagttt acgatagaaa aaaacgtggc
    14041 actatagcca cgttaaaatg gtatcacaaa gcaattttct ttgcaataaa aacaagtgta
    14101 ctaaaactac ctacgaggtc gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt
    14161 tgacgatttt gattatatag gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta
    14221 agaagatacc aagcaatccg gcaatatttc cagctactag aagaacgata atgatcgtta
    14281 atggatggat tttcagtgat ttcccaatta cattaggata aatgatattc ccatccaact
    14341 gttggacgat tagcacaacc acacaacaaa gtaatgcttt taccggatca ttgaagactg
    14401 ttactagaaa tgcaggtgct agtcctagat aaggtcctaa atatggaatt aggtttgtca
    14461 atcccgcaat gaccccaaat aagaaagcat aatccacacc aattaccata tatcctaaaa
    14521 atgtgaaggt accaacgaat aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg
    14581 ttttattcag ttgccccaat aactccacaa tttggtttct tcttttttct gggaaaaact
    14641 gttggatgtt tggcactagt ttttctccgt ctttcaacat atagaacaag atgaatggtg
    14701 ctgtaatgat tactacggtt gccgaagcga tcgttccaac gatcgaacct aaactattgg
    14761 atactccact aaggaattgc tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat
    14821 atttattgat atctacttcc ttgaacaaag gcaattcggc tacctctttt aaccagcttt
    14881 ctacctgttt gatgaaatca ggcatattag atgccaatga ggaaatttgc tgtactagac
    14941 ttgggatgac actaagtaaa atccaaataa ttgctgcaac taaaaggagc agcacaattg
    15001 cgacagccca tattcttttg atttttgctt tcatcaacag cttgacaata ggattcaata
    15061 aatagtaaag aaagcctgca atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga
    15121 tcggttcgaa aataaagttt atttctgatg aaatcatgat caatgcagct atgatcaata
    15181 attcaagcga ccaaaacatt agtttagact gtctaagttt ttcaaacaat agatttcctc
    15241 ctttctttct tactagtata tattatattc gttaaaaatt cttttattct ttttttattt
    15301 ttgaaaactt gccatacttt ttatttgttt tattttccag tatactatac gaaaggaagg
    15361 tggctagacc atgaaagttg tacaaacaaa agatacaatg agcaatattt acttagatgc
    15421 tgtacggatc aggcatcaag tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat
    15481 agacaaagat gaagcccatt gtatccactt cgtcctgtac tcagataaaa aagaaccgca
    15541 aggaactgta cgtcttttgc ctttagaaaa cggaaaaatg aaattacagc ggatggcgat
    15601 tctttctgaa tacagacacc aagggttagg aaaaatattg attgaagaag cagaaaactt
    15661 tgctaagaat caaggctata atacgatttt attaggggca cagtccacag ctgaaacttt
    15721 ttacgaaaaa ctaggatata cagcttacgg cgatcctttt gaagatgctg gcatgcctca
    15781 tatttatatg aaaaagactt tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct
    15841 tttgagaaaa atctctcact ggcttactgt tcttttttgt gtttacttac gcgacaattg
    15901 cttgtaacgg ttataccaaa tatcaatata gccttccgag aacgggccat ctccattatt
    15961 gatccagtca accagaatct tcacattttc ttttaggatg aagtcaatat cgttcgggta
    16021 attcatcatt ttgctgtgca tctcatattc atcgacatcc aatagtcgtt tctcgccgtc
    16081 aggaaatacc ttgatatcca agtcatagtc gatatatttc aaggcctcat cgtccagcaa
    16141 aaaaggtgaa gctagattac aataatagga aacccccttt tctctgatca ttgctattac
    16201 attgaaccag tattttttat gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg
    16261 tccatcagat tcagtgacta atgtgtgatc attcacgccg atcatagagt gttcgcttgt
    16321 ttttaatacc atggtatctc gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg
    16381 gatcgtcaca aactctcctt cttttggaac tcccatagca acccttcctt aagcagcatt
    16441 ttgtgctttg tgtttgggtg ttcattacac cgacatcata attattatat caataaaaat
    16501 gagctttgcc tagaaaggat tcctattgtt tcgatttttc tctaactgat ctaccagttt
    16561 catttggacc ttaggaaaaa cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt
    16621 tttgttctcg gtaaattctt gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac
    16681 atgccatttc agatgactaa aaatatgagt aacttctcct aaatgtcgtg tctgccaaac
    16741 aaagagttcc tgcttttcaa atgggagatt ttgctcttct tctgctacta ggtcatcaaa
    16801 cagatcgatt tctggctttg tttcccattc ttttttcaat cgctcatact cctcttgtgt
    16861 cacttccatc attggaaatg tccacatatt cgccagcaat ttttggctat ctctttcttc
    16921 aaaataatac gctccagaat gattttgaag agctgcactg atataataaa cgtcttttgg
    16981 ctttgctttt tttgttttta caggaaaact cgtttggatt cctcgtttgt tagctaaaca
    17041 aaaggcttgg atcggacaag tctcacactt tggagaagtt ggtgtacaga tagctgaacc
    17101 tagatccatc attgcttggt tgaattcacc tggatgcttt tcatcaatga ttttccgcat
    17161 cgcttcatca aagattttcc tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa
    17221 tctgctgact actcgcatca cgttgccgtc aactgcaggt tctggaagtc caaatgcgat
    17281 acttgcaatc gcgcctgtcg tatatggtcc tattcccttc aatgagctaa tttcttcagg
    17341 cgtttgcggc atttccccat caaattctga catgatctgt ttagcagcag cttggatgtt
    17401 ccgggctctt gagtaataac caaggccctc ccatgctttt aaaagctttt cttctggagc
    17461 atttgctagc tcttcaattg taggaaacca ttccatgaaa cgataaaaat aatcgatcac
    17521 tgtgtctact ctggtttgct gaagcatgat ctcagagatc cagatacgat aaggatcacg
    17581 attatagcgc caaggcaggt ttcttttttc ttgttcatac cattgaatga actgatcttg
    17641 aaattctttt gtttctttat ctgtccattt ttcccattct ttattcactt tcctcttcct
    17701 tttccgtaat gaatcgctgg atcatatcca aatcaaatcc tttttgatat aagctttgct
    17761 ttacttttag atttcttttt ttaggttcaa accttaaatt tcttcgccat agtttatctc
    17821 cttgtttgac taaataatca tattctattt cttgatctgc ttcttgcgga agatcagcta
    17881 tcgcttgttg gatcacttct tgagaaaagc ctttcgtcat caatgtttgt tggatttttc
    17941 tcaataattc tttttggctt tttccgtgat tttttccaaa cgctttttcg gctgtctgat
    18001 gtgcattttg aacttggtct tcaaatgtat attggctgag cgcttgttca atgatttcag
    18061 gtttcaaacc tttttgctgc atctgctgcg ctaatttctt tggtcctttg tcacttaagc
    18121 gcatattcgt gcgcacataa ctttccccat agaccaaatc atcgacaagg tccaattctt
    18181 ttaagcgggc tacgatttta tttcgatctt cttgaaggat ttccttttct tttaagtatg
    18241 ttcggatttc tttttccgat cgcaactgat aacttaagta attcattgct aggtgaaaac
    18301 cgaaatcagc tccgctactc ttcttgatct cttggatagt ttcttcgtct aattcccgtc
    18361 cttttaataa tcgatagcgt actaatacat cttcagatac ttgtaaagct tctccttcag
    18421 ataaatctac gcgatagaaa gggcctttgc ctttactgat tctcgtaacg gttaacataa
    18481 acatcctcct cgaacatata ttctctatca taccacagaa aatccccgta atcaggtatt
    18541 atatgttaga ataaaccaca gaaaaaagaa aaagggagat acttatggca gaaacaattg
    18601 tcaaaactgg acaaacggtt cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa
    18661 tcggttattt caaacggttg atcatatttg ttccatatgc actaccaaaa gaagaagtac
    18721 tagtgaaaat cacgaaagca actcctcgct atgcagaagg agaattaata aaagtcaaaa
    18781 aaacaagcaa agatcgcgta gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc
    18841 aattacaaca cttagcttat caagctcaat tggattttaa aaaggatctg cttttgcaag
    18901 cattggaaaa attcaaacca gcaggctttc gatcttatca acttttgccg acgatcggga
    18961 tggatgagcc ttggcattat agaaacaaag cacaatttca gttacgaaaa aataagcaga
    19021 ctcaaaaaat tgaagctggt ttatacgaag caaactctca tcagttagtc cctataacag
    19081 actgcttggt tcaagaacct cgaacacaaa aagtaatgaa tactgttgtt caactattga
    19141 ataaatttga tgcacccatc tatgatgaac ggacaaacag tggaatcttc cgcacaatca
    19201 tggttagaat cggtgttaaa actggggagt tacaagttgt ttttattact cgcagtaaaa
    19261 aattcccgca aaaaaacgca atgatccgtg agatcaatga acgactgccc gaagttgttt
    19321 caatcatgca aaatgtccag gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc
    19381 acttatgggg aaaagaagcc attgaagaac aaatcaatga agtgactttc gatctttctc
    19441 ctcgtgcctt ctttcaactc aatcctcagc agaccgaatt gctttatggc gaaggaatca
    19501 aagcattaga tgtccagcct aatgaaacga tcgtggatgc ttattgcgga gttgggacga
    19561 tcggcttaag tgtagcaaaa caagccaaag aagtacgggg aatggatacc gttcctcaag
    19621 caatcgctga tgcaaaaaaa aatgcggaaa gattaggata tcacaacact cgatatgaag
    19681 tcgggacagc agagcaagtt ctgcctaaat ggttgaatga aggttttcag cctgatggta
    19741 tcatcgtaga tccaccacgt acgggtttgg ataacgcatt gatccaatca ttattgaaat
    19801 accctccaaa aaaacttgtt tatatctcct gtaatgtttc tacacttgcc agagatctgg
    19861 ttaatttaag taaaaagttc aagattgaat atttacagtc cgtcgacatg tttcctcaga
    19921 ctgcacgttg tgaagttgtc gtgaagatga cgagactcgc tgactaaatg aaagaggttg
    19981 tgaaaaagtc tgccctgtat caagtaataa gaacagccaa acaaaaatag ctcttcatgt
    20041 tttatgaata ctgtacttgt gaccgaagag ttaacaggag gacactattt atttaaaaaa
    20101 agggttgtga catagttttt gtcacagccc tttttgatta ttattggata ttcacgtcta
    20161 tcacttgata aaatgcattt gtcgtatcgc tgatattcca tactgctaaa atcacattat
    20221 atccttttcg atcctgcgga agtgtgatcg tttggttgac tgtttttggt ggaacagttg
    20281 ctttgtcgtc tatttttgtg atcaattcaa aatcactaaa tttcaaaggt tgattaggat
    20341 tccaagttgg tttggtaatg tagtaatccc aagtacttgt ccgatgttgt gctgttaaat
    20401 tccaagtaat atttaatgtt cctggattaa ccatgttttt atgccatctg ttagatgtct
    20461 gttcatctaa aggctcaaag ccgctgactc ctgcactagc aatttttcca tcaatgaatg
    20521 tatttttggt agcttcgata ctttgcggtt cccattgtgc tcttccgaca ttttgattta
    20581 agtttcctgc tgctgatgtt cctaggtatg cacggcttcc tggagaagta atataaccat
    20641 gcgcaaaacc tggaatgcta aaaccgaaca accctaaact aactaaccca ataaacaata
    20701 acgtactaat ctttttcatg tagaaacctc cttcatttga taaccacatt gtaaacgctt
    20761 tattgtatta acacaaacat tatgctttta taattttatg ttgaagtaaa aaaggtgaaa
    20821 aaagtaagat gcagattata acagaagtag acgagaaaag tacaaataga aaacatgaga
    20881 atcaaatcat atgatctttt tcaaaaacat cattcatata aacaaatgtt caacttttta
    20941 ataacaacaa ttatcaattt ttttcttact tcacaaacta aatacaggtc ttgctgtgag
    21001 ccttcatggt aaactaatat tatagaaagg agttagtaaa atgaagatga taaaagatat
    21061 tcgtttttgg gtttgtgtta taggaattgt catattaggc tttttatcag ggttgcttag
    21121 cggaaatccc ggaaaatatt actattcttt gcaacttcca ccatttgcac cacctagctg
    21181 gatatttggg ccgatgtgga ccttactgta tatattgatg ggtatttctc tttatttgtt
    21241 acttaatcac aacaacaaaa aacagcgaaa caatcttgtc ggtctttttg tgattcagtt
    21301 catttttaat tttatatggt ctgctctatt ttttaattta agaaatattt tcattgcagc
    21361 aatcgatatt acacttttag ttattttctt gtcagtgctt atgtatcagt tgtggctgca
    21421 tcatcgcctg gcaatgtggc tcatgattcc ttattattta tgggtactat tcgcaactct
    21481 attgaattat tcaatttatt ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa
    21541 cacatagaaa aagtgccacc taagttagat tttttgtcta atttaggtgg cactctttat
    21601 taaccaaact atttttttct agtacccact tgttgttcca tactcattat tctggtcata
    21661 accataacca ttttgttcct gtccagcgta aggatcataa ctttgagtat cttgacttgg
    21721 tgtatagtac tgacttgtat cttctgtttg ctgataatag gtattcggat cttggtactg
    21781 atcatatgtg ttttctgaat aggaagaata atcggtgtac ccttcactat tcgatccatc
    21841 accgtttgtc gaatcgccat cttccgaatc atcaaagaac atcattgaag cattctcatt
    21901 tttcaaatta ggtaatgtat cgcttgtttt tatatttaat tgtttcttca gttcattttg
    21961 gatcgaaaga agatcatttt ttcctaaaat ttgatagtag atatcattga tcatttgtcc
    22021 ttcgccttgc aactggtctt gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac
    22081 atcaagcatg tcatcccaat ctaagtccgt cgtcacattg ttctcaactg cttttaaaat
    22141 ttttctataa ttgcttacgc catctaaact taaaacttta ttgacgattt tcgtcactac
    22201 ttcccgctga cgacgttgtc gaccgatatc gccttctgga tcttcgtgtc gcattcgaga
    22261 ataggctaaa cctttttctc cattcaatgt ttgttcacct actggtacat ggacaccatc
    22321 caaagtaaag tcaattttat tattcacttt gatgccaccg accgcattga tcaaatcttc
    22381 catgccatcc aaattgatcg ttacataatg atcaatagga atatcgagca gttgctcaat
    22441 tgaatccatg gccatttcga caccaccaaa tgcgtaggca tgatttaatt tatctaccgt
    22501 tccataacct acgatattcg tataaatatc tcggtccaaa ctgatgatcg ttgatttttt
    22561 ttgtttcgga ttaactgtta ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc
    22621 taatccaccg gtatctaaac ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct
    22681 tactctctca gaacgtttgg aggatattcg attagagttt ttagaaattt tgtttactgt
    22741 ttggctcgct tctcccataa atctgattcc gtatgctgat aatccggcaa tcagcaaaac
    22801 gaatacccct aacaaggtta atagaacttt ttgccatcgc ttcataatac acctctgttt
    22861 cacattttct aaaatattgt ctcatataac tgttcaatca gcaaattcac tttttaatca
    22921 taagaaaact ttaaaaaaca tttttgtgta acgattatta ttttttaaaa tttctcaaaa
    22981 ttcttaacta tcataccata ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca
    23041 atcgttttat ctttttttat gtattttttc cagaaaaagc gaacaacaag gtattttcca
    23101 aataatcgtg cagtaaaatg atcgcacata cctttcccat ctttttaaca gtctttgcct
    23161 accgttcaga ttatcattcg atttcacgac aatttcttcc tatgactggt ccttttgtta
    23221 aacccatctt ctattcgttt tatttccagc tcactgcatg gctcttaaaa tgactcgaac
    23281 tagtgattgc attaccatca tcttttaatg gatagatatg ctcctcttca aagtaaaacg
    23341 attttctttt aaagtaatag aattgacatg gtaatgagta tgtatactag tggtttcaca
    23401 aatggtcttt tattcaacat ccaaaaactg aaatttcttt aaaatccatt actaacgaag
    23461 aaaatgttcc ttgcttgata attagttagg acatgtcaag tgaacaaatg catttactta
    23521 gccaaaaaat ctaaaaactt cataaataga caaaaagaca cgactctcta agaagtcgtg
    23581 tctttattca acaaattatt ataatttagt cacttcagca gcttgaggtc cgcgtgcacc
    23641 ttcaacaatc gtgaattcta cttcttgacc ttcttctagg ctcttgaagc cgtctccttg
    23701 aattgctgag aaatgaacaa atacgtcatc tccgccgtct actgtaataa acccaaatcc
    23761 tttttcattg ttgaaccatt taaccgttcc gtgttccata aatgtatatc ctccaaaaaa
    23821 gttcttgcaa gtaaccttgc aagaacatta tacccaattt agaaaacgct agcaagcttt
    23881 cgctctttta ttttccaaat tatttttaag actgatatga cggaggaaat ggttattttg
    23941 ctgcttcgaa acgtttgttt acttcatccc aattaataac attccagaat gctgcaatat
    24001 aatctggtcg gacattttta tatttcaaat aataagcatg ttcccaaacg tccaaaccta
    24061 gaattggtgt ctttccttcc atcaatggag aatcttgatt tgcagtagag gtaatagcta
    24121 attttccatt ttccattaca agccaagccc atccagaacc aaatcgtcca gcggctgctt
    24181 ttttgaattc ttctttaaaa gaagaaaaat caccaaaagc ttcattaatc gcttctttta
    24241 tttctcctgt aggttcgcca ccagcatttg gtgccatgat ttcccagaaa aatgaatggt
    24301 tagcatgtcc gccaccattg ttacgtacag ctgtcttgat atctgttgga atagcgtcca
    24361 tatcagataa taattcttct attgtttttt cgcctaattc tgggtatttc tcaattgctg
    24421 aatttaaatt cgtcacataa gtattgtgat gcttatcatg atgcagatgc atcgtttctt
    24481 cgtcaatata aggttccaat gcgtcatatg cataaggtag atctggtaat gtgtaagtca
    24541 taaaaaaatt cctcctcaat gttttcttaa taatgtctac attacaaaga gtaacaaaga
    24601 gaaggaaatt cttcaattgt tatgcctagt cgtctttttc actttgacct acttcttctt
    24661 caaaaacctc agtttcttta aaaataaaca acttgctgaa aatatagttc gcaaggataa
    24721 caataatttg agtgatgatt ttcgccacat actcattgct gttcataaca ttgatcaaca
    24781 ataccattgc ccccatgtcc aatccgtaag aaaggatacg gtagaagaag aacttaccgc
    24841 attcaataag tgcatgtgta aaattcggtg attttgaatg gaatacccaa agtttgttcg
    24901 ttacaaaagc aaacaataca gaacaaaacc acgaaataga attggataag gccatactta
    24961 aatcaaaata ttggcgtgcg agagcaaaac taacaaaatt tacaatcgta gccaaaccac
    25021 caaaaaagag atagactagt atctcccaat atccttttgc ttctaaatat ccttttaact
    25081 gtcgatactg cttcatgagc caacctacct tattaaaaat tcttatttat catactctat
    25141 atttcaataa ctttcatctt tatttaaaaa aattaatttt ttttgatcct ttgcctttgt
    25201 ctctgcttgg atcgtcacat gtgtaatacc atattttaat tttaataaag aaattatacg
    25261 aggatatatc ttttcaatct cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa
    25321 aataattatc ttttcgctat actgccaaat atggacatga tgaacatcct ttaccccatc
    25381 gattgcttca atttcttgtt ccattttttc atagtcgata gcaggtgcac tttgtatcaa
    25441 aatagcggca gcttttttga tcaccattat cgcttctatc aatatatata tcgaaatgat
    25501 cagtgtaata actggatcga tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat
    25561 aatcacactt accgaagaca gtgtatcact taacaaatgc aaataactag attttatatt
    25621 caaactttca tctgcttctt gtcgtaataa taatactgag aacaaattcg cgagcaatcc
    25681 aataactgct actgttagca tcaaatgact atttatcttt tctggtgaag tgaaccgctt
    25741 gaatgcttca acggttaaaa acaaggataa tatgatcaat atgaatgagt tgatgaaagc
    25801 actcaatatt tctaaacgct ggtagccata cgtacgtttt ttatttgctt cttttcgggc
    25861 cattttttgt gccccgtaag aaaaaataat tgccaatgta tcactaaggt tatggaaagc
    25921 atctgaaaca agagacaaac tccctgacat aatccctcca ataaattctg ataaagtgat
    25981 caccgcattc aaaaccacta ctccaaatag tttttttgat gatctctgtg gctgtgtagg
    26041 cactattcct tcctccattt tatttatatt ggatagtctt tagacaagaa taacattttt
    26101 ttgatatttc accaatcatt cagctgtttc cttaaagcac ttgtatttca cttgatactt
    26161 cgctagaatt gcaagtgatg acactactag atgaggagta cttatgacaa caaaacaatt
    26221 aattatcagt tcctttatac gattcaaaga cctaaaggag gcgagaaatg tcccattttg
    26281 gaaagccatt gtctatcttt tagttttgag tataattatg gctttgccaa tctcttttca
    26341 agtttttcaa gtcttaaaca acattcaatt ggatgggcaa aagattgcta ctcgcattcc
    26401 tgattttaca atccaaaacg ggcagcttca aaccgaagaa aaagaaggat tcatttacca
    26461 aacaaactcc attatcttca catttgatcc agagggaaaa cgaacagaac aggacatctc
    26521 tactgatttg atggggaatt ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc
    26581 tcttcctaat acaggcacga cttctgcttt gttgaacaat aaccaattag aacttcccta
    26641 caccaatgaa tctttaaaaa acttaacagg taagcagctc cgttcttttt taagtgaagc
    26701 atctatacca ctttggataa aagtcctgac atttatattt tctatttatc ctagttttct
    26761 gaatctgctg atcactttgc tatttaccaa cattgctgct tttctctatg cacgctttcg
    26821 actaacaaaa gctacttttc ttgattgttt aaaaacattg atctattcaa tttcattgcc
    26881 tactataatt gcaacaatct tgatggtctt tcttccttct tttgacacta gcgccttcat
    26941 tgcttttgca ggaatcttta tttttgctca agctgtcaaa ggatgggcaa aaatatcgat
    27001 caattaagaa ataaagacaa ctcgttattt ctacttcaat agaccctttt agaggttgtg
    27061 acattttttt gtcacagccc cttttttatt tgaaaaatat ttctttctca aaaaacaagc
    27121 aaggcgcttc aaagttcttc ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt
    27181 aactatgtca gaaagaatca tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga
    27241 aatccatact atagcgcctg gttatatctt taaaacagaa ttacaaccag aggatctaca
    27301 aaatgtagag atcagtttgg gctggaactc agactaccaa gaaaaactat tagcctcttc
    27361 taccttgaaa tgggtccaat ctatctcagc tggtgttgat cagctacccc ttgagacttt
    27421 ttcaaagaaa catattttac tttcaaatgg tagtggcatc cacagtgaat cgattacgga
    27481 gcatgtctta ggaatcatcc ttgggtattc tcgtggtctt tttcaagcac aaaaggcaca
    27541 gagtgacatg aaatggttag gttcatcggt ccattaccaa tctatccaag ggaaaaaaat
    27601 actaatcatt ggaactggcc atattggaaa aatgattgca aaaaaatgca aagcattaga
    27661 catgaactgc tatggaatca atacatccgg tcatccagca gaaggaatgg aaaagacttt
    27721 ttctttaaat caactaaagg aagttcttcc tgaagtagat ttcgtagtca atatcttacc
    27781 tctaacggag gaaacaactg ggctctttga tcagcatatg tttgaacact ttgatccaaa
    27841 atctgtattc atcaatgttg gccgtggtgc ttctgttaag acacaagatc tggtgcaggc
    27901 tttaaataac cagcaacttt cctttgcagc attagacgtt tttgaggaag agcctcttcc
    27961 acaagatcat cctctttgga aaatggacaa tgtactgatt acttcccaca ttgcaggttt
    28021 gacacctgat tttcaaaaga aattaatggc tattttttta accaatctga aaagctactt
    28081 tgccacccat gagcttcaaa ccaatcaagt aaaattgtct gcaggatatt aatagctgaa
    28141 aacaatattt tcaaaagaaa aaagagaagg tgacaaaaat tgtgtcaccc tctctttttt
    28201 tattgttttt taaagtgata ggttggctcc tccaggttgg gattataatc aacaagtaaa
    28261 tcatatcctt taaagaacca ttcatctgct tcctcgataa aaaaaagtgt cccatcaatt
    28321 tccactttct ttacaggatg ttctggctgt tcaactgaca ttccaatcga aaaaccatca
    28381 tgaacctctg ttttgccgta gacttttcca aaaaaacgta ttccgtaagt ttctggcaga
    28441 tcaatttctg agtcaaacca cttttgtgct tttggcgtta ccgttaattt catcccaaca
    28501 acctactttc tcttttcttt ctattgattc atcttatcgt ctagaatatc cacatcgcct
    28561 gtctctccaa taaccagtag attatcattt tcacgaacat attcatctgc tgcaggagaa
    28621 gcgataaccg tttgatctac tcttcgtatg gcgactactg ttaagtcaaa acgttgcctg
    28681 aaatttaatt cagctaatgt tttgttgaaa aatttaggat tggagactcg gatttctgct
    28741 aaagaatatt tatctgacaa ctctaggtaa tctaaaatat tctttgacac taaattatgc
    28801 gcaatcctta ttcccatgtc tcgctcggga tggacgacgc gatcagctcc gatcttttca
    28861 agtactctgg catgatactc attttgggct tttgctaaaa tatttggtac gcccatttcc
    28921 tttaccatca gagtaactaa gatactggct tgaatatctt ctccaatagc gacaattaca
    28981 tgatcgaaat ttcttatgcc taatgatcga agtgtcattt catcctgtgc atttgccaca
    29041 acagcatgag tggctatatt catatattca ttgacccgat cttcattact atcaatagcc
    29101 agtacttctt gaccagcttc gatcagtgtt cggcagatac ttccgccaaa tcgtccaaga
    29161 cctacaattg caaaattttg tttcaccgtt ttcctccttt agtatcttct tttctcagta
    29221 taacaaagcc tttacaaaaa caaaagcaag catcattatt gtaaaaaagc caagaaaaat
    29281 aatagttatt ttctcagctt ttgattatcc tctttatcat cgtttttatt tcaccaaacc
    29341 atgtttgaat gcatagatag cggcttgtgt acggtcttcc acttctagct tagccaatat
    29401 attggaaaca tgtgttttta ctgttttcag tgtaataaac aattcgtccg ctatttcctg
    29461 attacttttt ccttcagaaa tcagcattaa aatttcattt tcccgattcg ttagttcttc
    29521 atgtaataca ggctcatttc gccgactcat tttttccatc atttttgttg tcacttctgg
    29581 ttctaatact cgctcgccac gttgcgttgc ccttatagca tcagcaattt catgtgcggt
    29641 agaggtcttc aacaaatacc ctgctgcacc tgcttcaatg gcaggataaa ctttttcgtc
    29701 atcaataaaa ctggttacga taatgatttt agcttctggc caatctttta agattgcttt
    29761 tgttgattcg ataccatcca tttcttccat gactaagtcc attaaaatga cgtccggtcg
    29821 aagtgtcatc gccttctcat agccttgtcg tccattttca gcttctccaa ttacttcaat
    29881 gtcttcttga atagataaat aaaaagagac gcctaagcgc accatttcat ggtcatctac
    29941 taataaaact tttatcatcc ttatctatgc ctccttcatc aaagggacct tgatttctac
    30001 acttgtacct tgacctttaa aactaatgat ttttactgtt ccaccaatac cagctactcg
    30061 ttctttgata ttgttcaatc cataacttcc cgttttcgtt tcattcatat taaaccctgt
    30121 tccgtcgtca ataatacgta acaaaagatt attgtctatt ttgtgcaaat atacctctaa
    30181 ttcattggct ttagcatgtc ttaatgtatt tgataacaat tcttgaacga ttcggaacaa
    30241 gtgatcctca atggaactag atagttttac atcttctaca tcccatttca gcgaaatctg
    30301 gattttattt tgcaattcct tcaataactg ctcgatacct tgctttaaac ttttctcttc
    30361 taaattgact ggacgtagat gaagaagcag cgcacgcatc tcagactggg aagcgttgat
    30421 gatctctgct accattttca actgcttgcg aaacatttct ggtgtctcgc ttttttctgc
    30481 ttgctccgtc aatgccgaca tcatcatcat tgctgcaaac aattgttgcg aaactgaatc
    30541 atgcagctca cgggctaatc gatgtctttc taattctaaa atttcttctt tggtttgtcc
    30601 atctacatat tggggacggc tcgttacaat ttgtaattca ctagatactt caatcatttt
    30661 ttcttttatc ttagtgattt ccttatcaat atctttgatg tataaatcgt ccgatgcact
    30721 tgggatcgga agaagcaaca atttggattc ataattgcca gaagaaagtg cacgcagctt
    30781 ttcttcgatt ttcccgtatt ttgtcttttg aataagtgat aataatagaa agacaattaa
    30841 tcctacacct aaggaaatgg ctaacaaatg gaagataagc ggaacatata ataaacgtgc
    30901 acgcagtaat tctccccacc aatgactttg attgctggca taaaaataag tgaaaagtga
    30961 aaatagaata ataaggaaag ccgcaatccc cgaataaaca gctagcatcg ctctggatat
    31021 ttttcccatc atattcgtat cacctcgaca tctccaatca aggtattagt aataatcttc
    31081 aatctacgag ggttttcatc ataatcactg ctgtagattt tgatttgttc atttttcaaa
    31141 gaaaattgct cttcttcaaa caagacattt cctactaatg tcgcatgctc taatcggatg
    31201 gctacgccca aaggtactaa gatccgtgtt ctgcctatcc cttttcttac aatcacaata
    31261 ttatcatctt ttggcaaaag cgtattgccc aaatctatga tagtatcacc agaaatgacg
    31321 gcgatgttga tatcgtccca ttcatagacg tcgtttccaa tacgttggtt accgaataat
    31381 tgctgtcttt tccgctcatt attatgtgtt tttaattgct ctgtttggat catcatgatc
    31441 tgtttctttc gccaaaaagc atttttggtt aaatctatcc ctgaaatctc tacacctttc
    31501 agaccaataa ataaaacggc aaatacagcc atcatccata aagcaggact gttgactaag
    31561 ctaaaaaaaa tgaccaaact tcctaatatc aattgaaaat tttgaaattt agtacgagga
    31621 tgtttgcgca tagctagata tatattgaaa ataccgaata tcactaaaag caaaagtcca
    31681 gtattgttta cgatttgcca aacagcaaat aacagcagta gtgcttcaac taccacaaaa
    31741 aaacgccaag aactattcat cgctctttct ccctcctgac acattctcat ttcatcatac
    31801 ctattttttt aactgttggc tataggactt tagatgtaag atcgtttgtt gaaatctaaa
    31861 atacacaaag agaaaaagat ctagagtgta tcatcagtaa gatgaactct ctagatcttt
    31921 cagtcagact acgcttgttc tactttgacg attttaacta acatatcgcc acctggagta
    31981 gcaatagtta cttcatcatt tttacgtttg ccaatcaatg cttgcgcaat aggagaatca
    32041 ttggaaattt tgccagaaaa cggatctgct tcagcgcttc cgacaatcgt gtactcttct
    32101 tcttctccat ctggtagttc gatgaatgta actgttttac caattgatac ctcatctgca
    32161 tctacaccgt cgttatcgat gatttgagca aaacgaatca tattttcaat tgttgtgatt
    32221 cttccttcaa caaatgcttg ttcatctttc gctgattcat attcagagtt ttcggaaaga
    32281 tctccgaaac cgcgggcaat tttgattcgt tcaatgattt ctccgcgttt gactgttttt
    32341 agttcttcta attctttttc taatttttct ttaccttcta gagtcattgg ataaactttc
    32401 tctaccatgt gtaacgtctc cttttttcga taaaataccg caaaaggtaa tcttttgagg
    32461 aatatagtcc aaaaaagatt accacgcttt tcttcaaatg taaatgtttt tctaaaaatg
    32521 atcaatgtct agagcctgtt tttctaagaa ttatttacat atttttccac taattccata
    32581 tgttcttcat aagttttagc gaaataaaca tttccagtgc tcgtatctgc tacgaaataa
    32641 taatagtcat tttctgctgg ttctaatact gccttgattg cctcttcgct tggattgtca
    32701 aaaggtccag gtccatagcc ggtattggta tacaaattat atggtgaatc tacagctgta
    32761 tcttcatacg tcactaattc tttgtgttca cctaatgcgt ataaaacaga gatatctgac
    32821 tgaagtggca tatttgcttt gattcggtta aagaagactt gtgcaatgtt tttacgatca
    32881 ttttctttta cgccttcttt ttcaactaga gaagctagag ttaaaacttc ttgtacagtc
    32941 aaatttttct gcttgatagc tgaataatag ttttgcatga ccgtattcgt cttgttcacc
    33001 atttcaatca ctagatcctt aagcgaagta ctcgtgtaat aatcatatgt ggctgggaat
    33061 aagtaacctt ccaaacggta ttttgtgttc tcagctttag atgcactttc caacagttct
    33121 gggaattttt ggtgcaactc gttaaagaaa gtctcatcat tcactaaatc taaaaattct
    33181 ttcttgtctt taccagttac cttcgctacc cgttcagcaa tctgatcgat atcgtaccct
    33241 tctggaatgg caattttccc atctgcaact tttgttggct cagaagtacc gccttcttgc
    33301 aactgtttgc caatctcgtc aagagtcata ttaggcgcta actgataata gccagcttga
    33361 aagccagtta aatttttaaa ttttgtataa taattgaaaa caatcccgct tttaataata
    33421 ttgtccttct ccaaaatctc accaatctgc ttgttagaag agccactcgg gatctcgact
    33481 tggactaatt ggtcatctga tttatctaaa ggcttcaacc cgctatctac ataacgatac
    33541 acggtaaatc caagaaatcc gccaataatc aataatgtaa gagcaatcac taaaatgatc
    33601 ttcctcacaa tcttatcttc ttttttacgc agatttctcc gcttgtcgat tatatctgct
    33661 gtagctgcct tactggcttc ttttttatct ttacttgggt gttgtttgtt tcctgacaaa
    33721 acaactcctc cttactatca agttcgtaac tttattcatt atacatgata tttgaattgg
    33781 cgtgaatgat tttatttaaa tattctatca aaaatgtaag tagtaaatcc attactataa
    33841 gattaaaata aatgttatca agatacaagc tattttagct ttattctttc tgtaaaaaag
    33901 aaaggagact aaataaacta ttatgaaaaa aggaaaacat gctaaaaaaa gaaaatattc
    33961 atttttaatg atcgttgtcg tgttgtttag ccttagtgcg ttctctacag gaactattct
    34021 tggatggcaa ttttacaata atgaacactc tcagatagtt gcccatgctc aatcagctca
    34081 aaaaaagttg atactgacta ccaatgaaca acagctcgtt gaaaaaatcg atcaactatt
    34141 aagaaaaaat gattatattg gctcaattta cgtaaagaaa aataatcgca tcatcatgga
    34201 aaaaggctat ggctatgcga ataaactcac gcaacaacca aatgatcctt ctctttatta
    34261 tcagattggt tcggttcaaa aagcattgac tactcttttg attttaaaac aagtcgagcg
    34321 tgggcacctt tctttagata ctaagctggc tcaattctat ccacaaattg ctggcagcca
    34381 gcaaattact atccgtgact tgctgtatat gcgctcaggc ttgcaccgaa ctgcttctcc
    34441 aaccataccg atgactgatg aagaagtcgt tcaatttgcg attcagcact taaaatttac
    34501 agattatcag acctctcatt atgattcatt gaactttacc atattgactg gaattttgat
    34561 caaattaaca aatcaaccgt atgaaaaatt attgaccgat gatatcatcg aacctttagg
    34621 attacagcat acaaaatttt atgaccaagt caaaaattca tccaatcatg cactatccta
    34681 tcaaatgtct aaagaggatg attactttaa accactgaca gaatctgaaa cagagatcca
    34741 taacgaatta gggactggta atatcagtat gtccgtctat gatttaaata cgctgtttac
    34801 acaagtttta tctggaaaac tagtttccaa agacttactc ttctcattat ggcgtgaaaa
    34861 tgcgaatgga catccatata gtggtggggt atatagcgga gataattata tcctgtcgca
    34921 aggaaatatc gactcttttg atacatctgc tatatttagc aaagattcac aggatgctat
    34981 catcatggaa agcaatataa aagctgacaa aactatcaaa ctgcctactg ctgatctaag
    35041 aaaccaaatc tatgacctga tggaaggaac tactaagttg gcaaatagct gatatgatga
    35101 aaagatagca aatactactt ctttgaatag catttgctta aaaaaagtac tcgactaaac
    35161 gtaggaaaga gtgtgggaca aatctaaaaa tcaatttttg ctacagactt taattccaaa
    35221 taaacagaac agaaagaggt gttcttcttt ctgttctgtc caaatta
//
LOCUS       DAZAOD010000014        34962 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000014 DAZAOD010000000
VERSION     DAZAOD010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.015"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="ACHDPO_000826"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="ACHDPO_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFN3368472.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="ACHDPO_000827"
     CDS             complement(2020..2922)
                     /locus_tag="ACHDPO_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFN3368473.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="ACHDPO_000828"
     CDS             complement(2919..3611)
                     /locus_tag="ACHDPO_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFN3368474.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="ACHDPO_000829"
     CDS             complement(3654..4295)
                     /locus_tag="ACHDPO_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFN3368475.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="ACHDPO_000830"
     CDS             complement(4333..4647)
                     /locus_tag="ACHDPO_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368476.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5264)
                     /gene="pyrE"
                     /locus_tag="ACHDPO_000831"
     CDS             complement(4635..5264)
                     /gene="pyrE"
                     /locus_tag="ACHDPO_000831"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFN3368477.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="ACHDPO_000832"
     CDS             complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="ACHDPO_000832"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFN3368478.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5984..6916)
                     /locus_tag="ACHDPO_000833"
     CDS             complement(5984..6916)
                     /locus_tag="ACHDPO_000833"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFN3368479.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="ACHDPO_000834"
     CDS             complement(6913..7689)
                     /locus_tag="ACHDPO_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFN3368480.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="ACHDPO_000835"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="ACHDPO_000835"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFN3368481.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /locus_tag="ACHDPO_000836"
     CDS             complement(10933..12009)
                     /locus_tag="ACHDPO_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFN3368482.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="ACHDPO_000837"
     CDS             complement(12014..13294)
                     /locus_tag="ACHDPO_000837"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFN3368483.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="ACHDPO_000838"
     CDS             complement(13313..14239)
                     /locus_tag="ACHDPO_000838"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFN3368484.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="ACHDPO_000839"
     CDS             complement(14252..15535)
                     /locus_tag="ACHDPO_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFN3368485.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="ACHDPO_000840"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="ACHDPO_000840"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFN3368486.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="ACHDPO_000841"
     CDS             complement(16323..17234)
                     /locus_tag="ACHDPO_000841"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFN3368487.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /gene="lspA"
                     /locus_tag="ACHDPO_000842"
     CDS             complement(17231..17695)
                     /gene="lspA"
                     /locus_tag="ACHDPO_000842"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFN3368488.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="ACHDPO_000843"
     CDS             complement(17700..18398)
                     /locus_tag="ACHDPO_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFN3368489.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="ACHDPO_000844"
     CDS             complement(18385..18771)
                     /locus_tag="ACHDPO_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368490.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="ACHDPO_000845"
     CDS             complement(18918..20588)
                     /locus_tag="ACHDPO_000845"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFN3368491.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="ACHDPO_000846"
     CDS             20771..21004
                     /locus_tag="ACHDPO_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFN3368492.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="ACHDPO_000847"
     CDS             complement(21103..21534)
                     /locus_tag="ACHDPO_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFN3368493.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="ACHDPO_000848"
     CDS             21613..22026
                     /locus_tag="ACHDPO_000848"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFN3368494.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="ACHDPO_000849"
     CDS             complement(22064..23212)
                     /locus_tag="ACHDPO_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFN3368495.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="ACHDPO_000850"
     CDS             complement(23334..23930)
                     /locus_tag="ACHDPO_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFN3368496.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="ACHDPO_000851"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="ACHDPO_000851"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFN3368497.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="ACHDPO_000852"
     CDS             27160..27591
                     /locus_tag="ACHDPO_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368498.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="ACHDPO_000853"
     CDS             complement(27636..28985)
                     /locus_tag="ACHDPO_000853"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFN3368499.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="ACHDPO_000854"
     CDS             complement(29055..30218)
                     /locus_tag="ACHDPO_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFN3368500.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="ACHDPO_000855"
     CDS             30347..30670
                     /locus_tag="ACHDPO_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368501.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="ACHDPO_000856"
     CDS             complement(30853..32202)
                     /locus_tag="ACHDPO_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFN3368502.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="ACHDPO_000857"
     CDS             complement(32271..33224)
                     /locus_tag="ACHDPO_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFN3368503.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="ACHDPO_000858"
     CDS             complement(33326..34516)
                     /locus_tag="ACHDPO_000858"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFN3368504.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            complement(34716..>34962)
                     /locus_tag="ACHDPO_000859"
     CDS             complement(34716..>34962)
                     /locus_tag="ACHDPO_000859"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368505.1"
                     /translation="IRKNRTVTRLLSQSFFRIQQVKLLRNIQRVKLKIADKRRWKFYV
                     FLLVYAINKLNIQNTIDFNERASINGCVIFICPGRVK"
BASE COUNT         9952 a         7641 c         6120 g        11249 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatataacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttcttccgaa ta
//
LOCUS       DAZAOD010000015        31759 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000015 DAZAOD010000000
VERSION     DAZAOD010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.016"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            516..659
                     /locus_tag="ACHDPO_000860"
     CDS             516..659
                     /locus_tag="ACHDPO_000860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFN3368506.1"
                     /translation="MITAHSGSDNTEENSWAFLRFCLDRQLCFEVDVRQQTDGTLILA
                     HDR"
     gene            726..1238
                     /locus_tag="ACHDPO_000861"
     CDS             726..1238
                     /locus_tag="ACHDPO_000861"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368507.1"
                     /translation="MTINCDLKEEGLEMAVFSLAQTYQIWPQIVLSGYVQLSWAAIWG
                     KHIFYNIENQFEGKKLGDITEADLIDTLQKLAYQSVQIVNIHEGWLTKLAREVGQQLG
                     LTFSVWTVNELETIEYLARCGVYNITSRCAWAYLWKKGAQNKLFYNQNRGVKRFGDGI
                     HDHMGALFLA"
     gene            1382..2671
                     /locus_tag="ACHDPO_000862"
     CDS             1382..2671
                     /locus_tag="ACHDPO_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3368508.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            2756..3628
                     /locus_tag="ACHDPO_000863"
     CDS             2756..3628
                     /locus_tag="ACHDPO_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013669610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3368509.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            3618..4433
                     /locus_tag="ACHDPO_000864"
     CDS             3618..4433
                     /locus_tag="ACHDPO_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3368510.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            4449..5573
                     /locus_tag="ACHDPO_000865"
     CDS             4449..5573
                     /locus_tag="ACHDPO_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368511.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            5551..6354
                     /locus_tag="ACHDPO_000866"
     CDS             5551..6354
                     /locus_tag="ACHDPO_000866"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFN3368512.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            6814..7077
                     /locus_tag="ACHDPO_000867"
     CDS             6814..7077
                     /locus_tag="ACHDPO_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFN3368513.1"
                     /translation="MAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQGKI
                     PFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            7061..7396
                     /locus_tag="ACHDPO_000868"
     CDS             7061..7396
                     /locus_tag="ACHDPO_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFN3368514.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(7575..8789)
                     /locus_tag="ACHDPO_000869"
                     /pseudo
     CDS             complement(7575..8789)
                     /locus_tag="ACHDPO_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            8990..10264
                     /locus_tag="ACHDPO_000870"
     CDS             8990..10264
                     /locus_tag="ACHDPO_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HFN3368515.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLHFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            complement(10647..11375)
                     /locus_tag="ACHDPO_000871"
     CDS             complement(10647..11375)
                     /locus_tag="ACHDPO_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3368516.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(11353..12927)
                     /locus_tag="ACHDPO_000872"
     CDS             complement(11353..12927)
                     /locus_tag="ACHDPO_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFN3368517.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            13156..14094
                     /locus_tag="ACHDPO_000873"
     CDS             13156..14094
                     /locus_tag="ACHDPO_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368518.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            14106..15017
                     /locus_tag="ACHDPO_000874"
     CDS             14106..15017
                     /locus_tag="ACHDPO_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3368519.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            15041..16513
                     /locus_tag="ACHDPO_000875"
     CDS             15041..16513
                     /locus_tag="ACHDPO_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFN3368520.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            16564..17175
                     /locus_tag="ACHDPO_000876"
     CDS             16564..17175
                     /locus_tag="ACHDPO_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFN3368521.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            17205..19118
                     /locus_tag="ACHDPO_000877"
     CDS             17205..19118
                     /locus_tag="ACHDPO_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HFN3368522.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            19246..22227
                     /locus_tag="ACHDPO_000878"
     CDS             19246..22227
                     /locus_tag="ACHDPO_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HFN3368523.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            22224..23885
                     /locus_tag="ACHDPO_000879"
     CDS             22224..23885
                     /locus_tag="ACHDPO_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein O-GlcNAcase"
                     /protein_id="HFN3368524.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            23925..24857
                     /locus_tag="ACHDPO_000880"
     CDS             23925..24857
                     /locus_tag="ACHDPO_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFN3368525.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
     gene            complement(25249..26796)
                     /locus_tag="ACHDPO_000881"
     CDS             complement(25249..26796)
                     /locus_tag="ACHDPO_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFN3368526.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(26898..27251)
                     /gene="tnpB"
                     /locus_tag="ACHDPO_000882"
     CDS             complement(26898..27251)
                     /gene="tnpB"
                     /locus_tag="ACHDPO_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFN3368527.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(27241..27435)
                     /locus_tag="ACHDPO_000883"
     CDS             complement(27241..27435)
                     /locus_tag="ACHDPO_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368528.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            complement(27661..28863)
                     /locus_tag="ACHDPO_000884"
     CDS             complement(27661..28863)
                     /locus_tag="ACHDPO_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3368529.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(28866..29060)
                     /locus_tag="ACHDPO_000885"
     CDS             complement(28866..29060)
                     /locus_tag="ACHDPO_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFN3368530.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(29107..29955)
                     /locus_tag="ACHDPO_000886"
     CDS             complement(29107..29955)
                     /locus_tag="ACHDPO_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HFN3368531.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(30160..30510)
                     /locus_tag="ACHDPO_000887"
     CDS             complement(30160..30510)
                     /locus_tag="ACHDPO_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368532.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            30688..31551
                     /locus_tag="ACHDPO_000888"
     CDS             30688..31551
                     /locus_tag="ACHDPO_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3368533.1"
                     /translation="MFGLVQPNKVKVGQRIKEIKDGMSLSFTELGNRLGLKKPTISSY
                     VQGYALAPKSVINQLSSISGKPVGWFYFGHVEEYIREYLFLIGQKKIVDDYPEIIEKI
                     KQEFYTGEFKNPAWENELGYPLEEFIQECFVEYSSEIMKDYVVQITKEVLEESKTLNK
                     LSSKAKEEAVTILSSGIIDYIEMSGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSY
                     LIGKLINILGTDEDTELFLSSLSMIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREK
                     TPDEFYDWFEK"
BASE COUNT        10009 a         5269 c         6355 g        10126 t
ORIGIN      
        1 ctgtctgtga ggacagcttt ttttgtgggc taggcatagc aaaaaggggt agtgacagtc
       61 cactgggagg gtgcacatcg accaatcgct agagaaacgc aaggtggtat ttgtgagaag
      121 atgacggaag aaatcctgta tcaaagactt ggttcaacga gcagaaatct gatagtaagt
      181 ctcggtcatt caatgggaat aagccattga acaccttgat ggtatcctgt aagaaagaac
      241 ctcaaggact ttcagcaaga agaaggaata gctgaaaaca aaaaaaggtg tagtaggtta
      301 aaagcgggga atgtagaact acttaattgg tgaaactagc tagaagggca aaatcgacga
      361 ttcatgagtt cgtaggaagg agcatgcaag atttacaact agtttactga aaaaacgcag
      421 ggaatttaca agaaattaac aagaaattaa cgcttcatcg gtatagtgga cgtgtgggag
      481 aaaatcacgg aattaaagga ggggtcaaaa tgaccatgat cactgcacac tctggtagtg
      541 acaatacgga ggagaatagc tgggcatttc ttcgcttttg tttggatcgc cagctttgtt
      601 ttgaagtaga tgtgcgtcag caaacagatg gtacgctaat actagcccat gacaggtaag
      661 aagttgtccc agattcggta acccttgagc aggtgtttca agcagtggcc aatgagaagg
      721 caaccatgac cattaactgt gatttaaaag aagagggatt ggaaatggcc gttttttcgc
      781 tggcacaaac ctatcaaatc tggccacaaa ttgttcttag tggctatgta caattatctt
      841 gggctgcgat ttggggaaag catatatttt ataatattga aaatcagttc gaagggaaaa
      901 aacttgggga tattaccgaa gcagatttga tcgatacctt acagaaatta gcctatcaaa
      961 gcgttcaaat cgtcaatatt catgaaggat ggttaactaa gttggcccgt gaagtggggc
     1021 agcagctagg attgacattt tctgtatgga cagtcaatga actagaaacg attgagtacc
     1081 ttgcgcgctg tggtgtttat aatataacct cacgttgtgc atgggcctat ttatggaaga
     1141 aaggagcaca gaataaacta ttttataatc aaaacagagg agttaagaga tttggagatg
     1201 ggatacatga ccatatgggg gctttattct tagcttgatg gatatgtcca gtgaccctgt
     1261 accccgaaat gcacaaattt cgaattattt acagaaaatt aactagaaat ttacattggt
     1321 agttcataat atttcttgat tagaaaaatg gccataaaga aattaggagg aagttaatgt
     1381 tatgttaaag aaaaatcttg ttataggggt tgtgtctgtt ttaagtgtca tctctttggc
     1441 agcttgtggt agtgggaata ccaagacaac aaaaaaatcg gagggtcgtg taacgataga
     1501 gtattggcat gttaatgcgg ataccctagg tggaaaaaca gtgaatgaat tagtagataa
     1561 atacaatcaa tctcaagaca aagtgaaggt tgtagcaaaa tataatcctg atatgtataa
     1621 aggcttgatg caaaatttac aagcttctgt tgcctccaaa gaaataccgg acgtagtaca
     1681 agtgggatgg gcttttaaag attattttgc agaaaatttc aaatatacta atcctcaatc
     1741 tttagtagaa gaagtggatc cggataatgc tgattatttt aaagatcatt ttttagacaa
     1801 tatcatggca ctgtctgaaa aagatggtaa acaagtgggt attccttact ccattagtaa
     1861 tccggtttta tatttaaatc aagatatatt aaaagcagcg ggcttggatg aaaatggtcc
     1921 aaaaacttgg gaagaagttc aaactttttc taagataata aaagaaaaaa ctggaaagta
     1981 tggcgtgtat attcaagaac ctgctgataa ttgggcacaa caagcaattt tagaaagtaa
     2041 tggggcaagt gtaataaaag atggcaaagc tacctttgct tctaaagatg gtatcgctgc
     2101 ttatgaatta tatcaaagga tggtaaaaga ccagacggca ttacacacta cgtgggaaca
     2161 aggtgtgcaa agctttattg atggtaacgt cgcgatggtc tataccacta ttgctcaaag
     2221 ggacaacatt caaaaaaata gtacttttac tgctaaagca gttgagtcac caagttggga
     2281 agggaaaaaa gttaaactac ctgctggtgg cgcaatgtta gctgttacat cacaaacgga
     2341 taagaaaaag gaagcaactt gggatttctt aaaatatctt tatagtgttg aatctttagc
     2401 taaatggaca gaaggtactg gttatttacc accacgtaaa gatgttgcag acgcccaaaa
     2461 tggattaaaa gctttcttag ctgaaaatca gatgatgata ccagcaattg atcagatgga
     2521 taagatggtc agttggagtt catttcctgg agatgctgga ttagaagctg aacaaaaatt
     2581 gttggatatg cgggataaaa ttttatcagg taattccgtc aatgaaacga tgaaagctac
     2641 tcaaaaggaa attaatgagt tactcaaata agcaaagcaa gcagacgaca gcgcctgtaa
     2701 gaaaggaaaa acaaggtcgt ctgcttttga cataaggatg aggaggctgt cggaaatgaa
     2761 gcgctatgta ggttatttgt atctggcgcc agcaattatt ttgttgggcg tgtttgtttt
     2821 ttatccattg atttatacga tctatttgag tttttttgac tggaatatgg tggcccccac
     2881 taaagaattt gttggctttg ccaactatgt aaaggtgctg actgatccag tctttcataa
     2941 agtgttgaag aatactttgt cctataccgt tctatttgtc ttgctgagct gtgtgttccc
     3001 atatattaca tcctttttat taggaatagt tatagaaaaa gggcagaatt tgtataaacc
     3061 attatttttt attccagctg tgatttcttt ggtagtggcg gggatggttt ttacatggat
     3121 attaaatccg gtatcgggac caattgctgt cttgttggga aattttggtt taagactgcc
     3181 tatgtggatg aatttacaag gttgggtaat tgctgtgatt gcaggtatta ctgcttggaa
     3241 agtttttggt tataatttca ttgtcatttt tgcagcaatt gtgggaattg atcaagagat
     3301 gatcgaagca gctaagttgg atcgtgtacc catctggcgc atttttttta caattgtgtt
     3361 gcctatgagt agttcgacag gactatattt attggtgatg accattgttc aaggtctgca
     3421 gtatgtgttt actccgatta agatcatcac tcgtggtgga ccgaataatg gtagtgcaaa
     3481 cgtgatctat tatgcttatc aaaaggcttt tgaaatgtat aaagtcggag aatcttcagc
     3541 aatttcagtt ttaactttat taatatttgc tgttttctta ggggtaatat ttaaatttgt
     3601 ggaaaagggg gtttactatg aaaattaaac gctggttgcc acatctctta tttatgttca
     3661 tcataatcat tattatctat ccattattgt ttattatggc caattctttt aagccattga
     3721 aagatgccta tcagacgatt actagtttga taccacagcc gtttaccttg gaaaattttt
     3781 gctatttgtt cgaaaatctt ccaattatca aaattacgag aaatactttt tttattgcta
     3841 caattataac ggttgttaag ttaggcgtag ctttttttgc ggcatatagt tttacttatt
     3901 gccgaatcaa agggaagaaa atctggtact ttatcatcat tggtacgatg ttcattcctt
     3961 ttactgttgc gatgattcct aattatttgt tgattgcaaa acttaattta attgatacta
     4021 cttggggtgt gataatacca caatttgctg atgcgatggg cattttttta ttgacgcaaa
     4081 caatgcggga aattccagtg agccttctag atgtggcggc attggataac atcaaacaaa
     4141 caaccgtcat gagtaaaatt gtttttcctc ttactagaca tgcgattact tctaccggta
     4201 tttggttttt tattacctct tggaatgagt atgtttggcc ggtattaatt ttacggacag
     4261 tagataatta tactttgccg ttggcgatgc agacctatat tagttctgaa ggtgggacaa
     4321 attttaccgt agcaatggcg attagtttaa ttacaatgtt tgtaccgtta gtcttgtatg
     4381 caatttttca aaaatatatt atcgggactt ttgtttctgc aggtattaaa taaattggag
     4441 gacaaatcat gggagaaacg cttgaattaa gaaatatcgg aaaaaaatat ggagaacata
     4501 ccattttaaa agaaattgat ttagctgtgg ccgctggaga acgaattgtg ttactgggac
     4561 catctggttc aggaaaatct actttgctga gaatgattgc tggtttggaa aaaattacga
     4621 gtggagagct ttttttaggt acacaactag caaataagct accttgtgga gaacgagaga
     4681 tcgcaatggt ttttcaaaat tatgctttat atcctcacat gactgtaaag gagaatatta
     4741 tttttgcatt aagggcgaat aaaattaaga cagctgacat tcagcaccgt ttggaagaag
     4801 ctttgaagat gttaggttta acgccatacc aagatcgact tcctaaagat ttgtcaggag
     4861 ggcaacggca gcgtgtagca ttggctcgtg cggtggttaa acggagtaat tattttttat
     4921 tagatgaacc gttatcaaat ttggatgtgc gtttacgatt ggatgcacga aaagaattgg
     4981 taaaaattca tcaacgttat aaacaaactt ttgtctacgt cactcatgat caaattgaag
     5041 cgatgacgtt agctgaccgg attgttttat tgaatgaagg tagaattcag atgattgata
     5101 cgccgaaaaa tgtttatacg aaacctaaaa atacttttac tgcaaatttt attggttcgc
     5161 caggcatgaa tattatgcca gttacttatg atcaaggaac attaaaggta gccagtcaat
     5221 ttttaacatt gaatccagct tggcaaaaac aacttcttca ggttagtggc tcattgtatt
     5281 taggcataag accagaacac gtaacctttt caaaagaaac aagcgattta cacggtcaag
     5341 tgaagtatcg tgagctatta ggtcaaagtt atgcgtacac cgttaaagtc gatggtatag
     5401 aaatgattgt ccttaatgaa aaacctactt ggcagattgg tgatgcagtc aatctccgca
     5461 tagaacctga aagaatgcat ttttttgatt atcagacgca agaaaattta ggatatcctg
     5521 attattttat tgaagaaaga gggaatagcc atgcgctttt tgcatctctc tgatatccat
     5581 tttagagaaa actatcaaac taacttgttt actgctgaac tatttccaac aattaaaaat
     5641 ccacagttgg cattggaaaa attgttacaa gaactctcgt taacagtgta cgattttatt
     5701 ctattaacag gtgatttagt acatgaaggg gggatttctg attatcaagt cttacggaaa
     5761 atgttggatc aatatttccc aaccacacct tactattttt gtcgtgggaa tcatgatcgt
     5821 cgcagtgttt tctttgaagg aatgagtgtt gaaagcaatg aaacgggaga gtatatccat
     5881 tgtacgaatc aaaatgggtt acgaattatt tccttggatt ctgctcaaga tacccagcac
     5941 gaaggaaaaa tatcgatagg acagatgatt caattacaag agtggttggg tacacctgct
     6001 gaaaagggaa cgattttatt ggttcatcat ccattgtcgt gggaagatcc atctattgta
     6061 actgaagttc cggaaggttt tgctgaattg attgccgaaa gtgatatttt aggtattttt
     6121 gtaggacata tccatcaagg tagcagtgct gaatttgctg gtaaaaaaca gtttatggct
     6181 gaatctttat catttggtgt agatgaatac ccagactatt ctctttttac caatagaaca
     6241 ggattcacta gtggcagttt aattgacgga aaaattttta cttatcagca ttatttaact
     6301 ccacatcaaa tagaaatagg gcgcatgaaa aaaccaatta ctggtaatca ttaaaaatta
     6361 ttgattaaaa ataaagactt cattcacttt ttagccgtgg tgctcaatgt ctggttccac
     6421 ttgaagaact tggaaaatcg ctatcaataa accactatcc ctccaattac aaaaagggtg
     6481 gagaaagttt tccaagaacc atatcggtct tcgtggttgt gccattcgtt ttttaccaga
     6541 gcataccaca tctttgtgga gttttcagac acgtcctagt taatttggtt cttttaggag
     6601 tcttttcctg ttctgtgtgt cgttgagtgt tcgcttcaat tatcgctgtg gcggattttg
     6661 aaacttttct atctatcaag gccatttagc actatatcct ttccttatat ttagataaat
     6721 acactgcatt tcaaggagtt caaaagtagt tgtattaatt ccatttgaac tctttccgtg
     6781 atataatgtg tttgtcagaa agaggtggag aaaatggcta agttacaaat ttctatggac
     6841 gaaaaattga aaaatgaagc agaaagcatt attgatgaac taggcatgag ccccaaaaca
     6901 gccgtcaccg ttttttataa gcaaattgtt gagcaaggaa aaatcccatt ttctattgaa
     6961 ttgtcggaaa aaagtaaacg aatccataat attcaaagat tagcggaaaa attgcctgtc
     7021 caaaaactag acactgacga aaaaattgaa gaatggttca atgaagatga atactaatga
     7081 tatagcaacc gtctacgttg ctttcacagc tgcagagggc ggtaaacgcc ggcctgtcta
     7141 tattctaaaa aatggactgg acacaatttc gtttctgtca attacttcaa aatatcatac
     7201 taaatccgat aaaataaagc tgaaatacgt tgaaataagg gattggaaac aggcaggact
     7261 aaaaaaagaa tcttggattg acgtaggaac tctaaacgaa ttacccaaaa acaacaaaaa
     7321 ggtcaaatgg aaaaaaattg gggaattaag tccaagcgat ttacagcgac tggaagaacg
     7381 catggaagaa ttataataat actaaaaaga agggctcttt gtcaataagg actgatgggt
     7441 tgtacaaaat caaatctggg tcagaatgaa cctcattctg gctcagattt ttggctcttt
     7501 gtcaataagg actgatgagt tgtgcaaaat caaatccggg tcagaatgaa ccacattctg
     7561 gttcagattt tttgttatct tacattgatt aattgattga tcaaaaagat tctaattctc
     7621 atgttctcga atgatttaaa tccgtaggat actcgtttca ttgtctttat gtgggtattc
     7681 ttcgcttcaa tttttccatt ggaataagga tagatcattg cgctggtgat accttcttca
     7741 taggtcagaa ggttttgaag cttctcccga aagccgtcat ctaacgtttc gggaagttct
     7801 gccaataagg agaaaaataa gtcagggtct ttgtctcgaa aggcttcgac taattcatga
     7861 aaaaagggat acgcctcctt tagaggcgca gaaaactcaa gcaatcgatc aatcatcatt
     7921 gcttcagtga gaaatgggta ttttggtgct cggaaacttt tccatgtttt gtactcataa
     7981 tggttgatgc ttgcacgatt ttttagcaga aagcgccagt tctttttcag tttttctgcc
     8041 tgacttttct gtcctgcttt acgaagctca ttcatttcac ggatacgcaa ctcattgagt
     8101 gcctgattca tgtgtttgac aatatgaaac cgatcaatca ctactttcgc atttggcaga
     8161 acacgtttgg taagctggaa gtaagcggcg ttcatgtctg tgactaagaa ttctacttct
     8221 tctggattgg tgcagcctaa gaaatagctt gttaatcgag gtaatttacg cgtaggcaag
     8281 acagcaatta agtttcctgt ttcaccatct gcgcaaataa agctcatttt atcttctatg
     8341 gaagcgtgcg aacgaaattc atcaaccatc aatactctgg ggagaatctt cttagaaggc
     8401 tttggtaaat agcttttaaa ctctttcaat gtacgagtaa cggtagtcaa agatacctga
     8461 caacttttcg caataaaaga caaagatact ttttcagtca gtaaagaagc aattttatat
     8521 cgaacatgat ctgcgattga atggctgagt cggacaaaat aactttgagc cgtccaatgg
     8581 gtacgacagt ttttacaggt atagcgttgc ttttttaggc gcgtaaccaa aggcatatga
     8641 ttgtattgtt caaaacggac aatcgtttcc ttcttcccat ttttcactat aattgctttc
     8701 ccgtttccat ctaccacagt agaaccacaa cttctacaag cacgaggagt aggcgagaga
     8761 acagcatcga cgaccaacgt ctttttcttg gctctttgtc aaataggact gatagagtga
     8821 tataagaaca tctaaggtag aattgatttt gcttctataa tattttgtgt tggtggaaaa
     8881 tcgaaggcga ttttctacta acactttttc ttcgtttcaa ctcaaaaaga gactcacttt
     8941 tggtaaaatt tagtcgacca aaacgtcatc ctaccaaagg agtctctcaa tggataatca
     9001 tactagaaaa ttactcggat taacagataa acatttattt tttgatgaag aatggctgat
     9061 tgaaaaagaa tataaaggcg ttcaagcgca gtttattaaa ggaaaattgg atgactctcc
     9121 ttcctattgt gaacactgtc gatcggttcg tattatccgc aacggttcct atacgacacg
     9181 cactcagata ttgaaagtca aagaaaagtt aactatttta gaattaaaac gtacccgttt
     9241 tctctgccat gattgtggaa ggaccttttc tgcgaaaacg gacttagttg atgaacatca
     9301 tcaactaaca aaggaactga agcaggcaat tctcatggaa ctgtacgaaa atcaatcacg
     9361 taaactaatc gctaagaagt acttcgtctc ggatgggacg gtgacacgga tcttgcgtga
     9421 agcaacgaag cattaccagt cacgtatgaa cttccttccg acggtgttgt gtatggatga
     9481 gttcaaatca atgaagtctg tttctggttc catgagtttt atttgtgttg atgggacaac
     9541 ccatcagcta tttacgatcc ttgaagatcg cagactttac aaactaactc aatacttcct
     9601 gcactttcct agaaaagccc gtttaaaggt caagtaccta gtgatggaca tgaatgccag
     9661 ctattgtcag ttgcttaaaa cagtctttcc aaatgcggag atcgtaactg accgctttca
     9721 tattgtccaa cacatcaatc gcagcttcaa tcaattacgt gtccagatca tgaatcgttt
     9781 tcgaacctca cactctgaaa atcagaagaa gtaccgtcgg ctcaagcgat attggaaact
     9841 cttactcaaa gattccacga catgggagcc actcaaacgg cattatcatc gactgtttaa
     9901 acgaccaatt agtcaaacag aaatcgttga tgagctgtta agctacaacg aagaattgcg
     9961 aactgcgtat catttttgtc aattattacg ctattatttc gttaaacgag gtacggaagg
    10021 ctttcaagaa acccttaaaa caatttcatc tacgttacct cagtcgttta aaaagaaatt
    10081 cacgatcttc cattgctacc aatcgggtat ttcaaatgcc tttaaggtgt cccactcaaa
    10141 cggcgtcact gaggggctga ataacaagat caagctgatt aaacgaattg cgtttggtta
    10201 tcgcaacttt tataactttc gggcacggat ctatttacaa caaggtctga tctttgaaaa
    10261 ctaaaaaaat atgcggcgca cagaacgcgc cgcatatcgg actaagtttt attcaaattt
    10321 gtcttcacca acacgatttg acgaagagcc tatttaaata actacatcca tttattctat
    10381 cttctaaaat agcctttttc atttcagtta aatagttcag cgccattttt gcactcgact
    10441 tgcatagtag ttttttccat attcctcaac ctcagcgggg gttgaagaca taaggaaaat
    10501 cctatgcgtt atgctcaact ggatctgatt aaatattcta atgtattttt ctctaccatc
    10561 attaaatggt taatagccaa aaatcaccac ttttcaatgg ctccttgttg tataagtata
    10621 actagaagat gaacacgtct gagaaattat agaagctttt tacggtaatt actggggctg
    10681 tgtccagtag tttttttgaa gagaacagaa aaatagctca cgtgatctat tcctactttt
    10741 tgactaattt catcaataga taagaatgtg tctttcagta gagcacttgc tcttttgatt
    10801 cgaaagtcta gcaagtaatc atgaaaggaa taacctgttt cttttttgaa ggcccgtcct
    10861 aaataagcgg gatggtaatg gaattgtgta gctacatctt tgagcgtaag cttttcacta
    10921 taattgtttt gaacgtaatc aatcacttgt tgaattgact cattaaaaga atcatcagtt
    10981 agagagtttt gattagctgc tgatttacgc attttttctt cttgtactaa cttaactaaa
    11041 taaggaaaat caatgggttt cgttatgtaa cttttaatag ataaatcaat cccctttttt
    11101 gcatactgaa aattttggtg ggcactaatg acaatactag taaagtagcg attggatgtt
    11161 tgttgcaaag attcgattaa ttcgagtcca gaaattttcc ccatcgtaat atctgtgata
    11221 agtaaatcaa agcgctggtt ttgcaggttt ttaaatgctt cgtctccgtc tgtgtagcag
    11281 tgatcgataa tgatgtcggg gactttcttc aaaagataat gccttatgcc ttctacaatt
    11341 gtacaatcat cgtcaacaat tgcaattctc aacatgcata ttcccccctt tttgtatttt
    11401 gatagtaatc gttgttccga cgtgtagttg gctttctata acaaaacgtg tatctccagg
    11461 atagagatgc tttatacgtc gaaaagaatt tgagatgccg atattctcac tataaggaat
    11521 atcatcatta agtttttgtt gaatatgctc cagcttgtct tggtccattc ctttcccatt
    11581 ttcaacgatt tttaacacat aatggttggt tgtttcagtt gcatagacag tcaaacgatt
    11641 ttcctttttt gatgaatcga agccgtgttt aatataattt tcaacaaatg gctgtaaaga
    11701 aagttttggt aacattaatt gatcaatatg atcaatcagc tgatagtcaa agttatgtcg
    11761 ataacgacgt tgatgtagtt gcaaggagag gtcgatatta attaattcct ctttcaaatc
    11821 aattatgtcg ggctgatatg tattattgcg atacaacttg ctcaataaat atatactgtc
    11881 gctgatttct tcgtcatcat tcaatatggc agtcattcga ataaattcca aattattaaa
    11941 tagaaaatga ggctcgattt gatattgaag tgctgcatac tttgcttctt gcttcaacca
    12001 attattttca taaagtgttt tttgatatgt agcattatct aaataaaact gattgatatg
    12061 catagcgatt tctttcaaat caccgacttt gttttcgata ttgattgact tgtagtctcc
    12121 tgtagatgaa tgatttaagg aagtaatgat ttcctgatac tgctggatat agttacgaaa
    12181 acttctattt aataattgat gaatagcaag aataaacaaa ctcattaata agaaaatcat
    12241 gattgccaga cctaataagg tttgtgacga ataatttgga ttttcatata cttgtaatgt
    12301 gtggttaccg atagctatct gttgcgtttt tttccattta gaaggcgaga tgtcttcaga
    12361 taaattgacg gaatcaatac cattagacaa agaataattg taatgtgttg gaaagagact
    12421 cttttttagc gcgttgatcg aaacgtctag aatcaatgta gcatcgggca tgtcctcact
    12481 aatgaaactt aatgaacgaa taaaagaaat tttttcgttt tttgtaggtg cgtaggcact
    12541 taagtatttt tcgtaatcta atgagataga tatattttta acttcatcat cttgcacaag
    12601 tttttttaag ttatctacta aataggtagg ggagcgatcc tttgacaaaa tatcttccat
    12661 gtattcagca ggtgatgaga ggtagtagtc attaaggttt tcttggaaat cataattttg
    12721 atagatctct gtcacgatac cggagagaat acgattatat gtttccatat agtgggtgat
    12781 ttgctgaatg ttttgcaggt tttgattttt ttctttttca atcacattga tataggaaaa
    12841 gaacaatgtg aaacaggcaa gtaaagtaat aaaaaaaatc aatatgtatg taaaacgcat
    12901 aataactttt gataaatcgt ttttcattca aagtcctcat tttgataatc tctaatttta
    12961 tgaatcatta tagcacatat tacaagtgat gtaaacgctt tgcaaacagg gctacttatg
    13021 attgtgaata cagtttccgt ttaaaaacta ttctattgta gaggtttaat aaactaaaaa
    13081 taatgtataa aaaattaatg taagcgatta accaagtggg tataatcaag gaaacgctga
    13141 gagaggagag acaaaatgaa gctaaagaaa gggttattag gaaatctaaa aaaaaaccga
    13201 gcattgttta ttatgctttt accaggtgcg ttatggttat ttatattttg ctatatacca
    13261 atgtttggag ttgtaatcgc ttttaaagat ttcagaattt catcaagggg attctttaca
    13321 agtttgttca acagtccttg ggttggctgg gaaaatttca aatatctctt tgcttcgcaa
    13381 gatgcttgga tcattactcg caatacggtt gtttataacg ttgtaggtat tttgctaagt
    13441 actttttgta cagtgtcatt agcaatcatt ctgagccaaa tggcgaacaa acggttattg
    13501 aaaaagatgc agacatttat gatttttcct aattttttat catgggtagt catcagttac
    13561 tttgtttacg catttttgag tacggataaa ggattaatta atattttact aagcaatttt
    13621 ggtgtggaac ccataaattg gtatagtgaa ccgaagtact ggccttttat tattgttttt
    13681 acgagtttat ggaaaggcgt aggctatgga tccatcattt attacgcgtc aattatgggg
    13741 atcgatacta gttattatga agctgcttta gttgatggtg ccagtaaatg gcaacagata
    13801 aggaatgtag tcttgccaca tttaagatcg attattgtca ttatgttgat tttgtctgtt
    13861 ggtagtattt ttcgagctga ttttggattg ttttatcaat tgccaagaaa ttcgggggct
    13921 ctttatgatg tgacgaatgt attagatact tatgtctacc gtggattaat gaatagcgga
    13981 gatatcggaa tgtctacggc agcgggatta tatcagtcat cagttggctt tgtcttgatt
    14041 ttgattacta ataagatagt caacaagtta gatcctagtt cagcactatt ttaggaggaa
    14101 tcaaaatgat atcaaaatta aaacggcaga tgtacttttc gctgccagtc gaacggtttt
    14161 tcacaatatt actaatctta tttactctta gctgtatttt tccctttatt ttcgtaatcg
    14221 tcatttcatt aacagatgaa aaagcattac aactcaacgg ttacgaatta ttgccggctc
    14281 aatggagcac tgatgcatat caatacttaa tacaagatgg cggacagtta cttcggtcat
    14341 taggcgttac aattatgatt acagtgattg gaacgttgat tactgttttt atgacgggaa
    14401 cctatgctta tgttttatca agagcctctt tcccttaccg gaagttcttt actttttatc
    14461 ttttttttac catgttattt gcgggaggga tggttccttc ttacttagtg atgacgaaga
    14521 tgcttggctt aaaaaataca atttgggctt tgattctacc tcttgctttt agcccataca
    14581 atgtcattat tttaaggaca ttctttaaga agtcgattcc agaatcgatt atcgaatccg
    14641 ctaaaatgga tggctgtagt gagtttcgag tttttttcca aatcgttttg cctttagcga
    14701 tcccaggggt tgcaacaata ggtttatttt caagcttagg ttattggaat gactggttca
    14761 acgcattgct gtatattgac accaacaaat tgattccatt gcaatatttg ttaatgaaga
    14821 ttcaaaattc aatggaattc ttagcaaata ataatgacat tacattagcg cagcaacaag
    14881 caattcaaaa tagccttcct caagaatcaa cacgaatggc aatggtcgta gtagctactt
    14941 taccgattgc aattgtttat ccgttcttcc aaaaatactt tgttcaagga ttgacgatcg
    15001 gtggagtgaa agaataaaaa agaataggag atgttaaaag atgaaaaaga acatgcagaa
    15061 atatttgatt ggtggtgctt ctgtactaac ccttggccta ttaggtgctt gtggtagcag
    15121 taatggcgaa gcaaataatg aaacaggaac cacaaaagtt acttggtatc aggttggaga
    15181 agaacccaaa gattttgatg aggtcatgac aaaagtcaac gaaaaattaa aggaagaaat
    15241 caatgtagag ttggatatgc ggctgattcc ggacggggat tatcagcaaa agcttggtgt
    15301 gatgatcaat tcaggagaag aatatgatat ttgtttcgtc aatggcacag attatgtgaa
    15361 ttatgggaac aaaggtgctt tcattagtct caacgatcat ttggataaag agttgaaaga
    15421 ttatgcagct gaattgaatg aaggatttat tgaaggtggg gcaattaatg gcgaaactta
    15481 tggattgcca gtcaataacg atattgccac aacggaatat tggaccttta ataaagattt
    15541 ggtagatcaa taccaattgg atgtagagaa tgttgaaggt gtagaaacat tggctccagt
    15601 attagaaaag tttgcagaaa aaaatactga tacgaatatt acgccaatcg gtatgacccg
    15661 taccagtgtc tgtattcctt atgacaatat tatcggtggt ggtgtaccgc tagcggttgc
    15721 atttgaaggc gatacacaaa cagttgttaa tacttatgag actccagaaa tgatgactta
    15781 tttgaaggct atgcatgagt tttataaaaa aggatatatt ttgaaagatg cagccactgt
    15841 tacgacagat ccatttcgaa ttgatagtaa aaactggttt ttaggtcgta actcaagtgg
    15901 ttatcaacca ttagcacaaa aaaaattaga agctctagcg ggacatggat taattttaaa
    15961 accagctgga aaagctttta aaacgactgg atttgcaaga gtggcaatgc atgcggtatc
    16021 tgcttcaagt aaacatccgg aagcagcctt gaaattgttg aattatgtga ataccaatca
    16081 agaagtagcg gatttaatgg tttatggaat tgaaggaaaa cactatgatc gcaatgaaga
    16141 tggttcgatt actttaacaa actctgatga ttattatcaa ggcgcttggg cattggtaaa
    16201 tacttatcta gtttcaaaaa cttcaccgat tacagaagaa agtaaaaaac tagaagaaga
    16261 aagtaaaaag tttcaaaatg aagcaccgat gtctcctatt ttaggtttct cttttgacgc
    16321 ttctgatttt cgaacagaaa ttgcaagtgt acaaaatatc gtgtcacaat atgaagtact
    16381 tttaagctcg ggaacagttg accctgaaca atatgtacca gagttgttag aaaaactaga
    16441 aaaagctgga ttggataaaa ttcaggcatc tgctcaagaa caatacgatg aatggcgaaa
    16501 atctaacaaa taatttttta ctaaatgaaa agaatagact aagcagttag tggggggatt
    16561 caaatgaacg aaaacaaatg gaccaaagga tttaattggg tttttcaatt gttgttacta
    16621 aactttactt attttatact aatttgttta ggatttggaa ttttaggttt tttccctgct
    16681 acgatagctt tgattgctgg cgttgtgaat cgaaaaaaat atggcttgca agagtctgtg
    16741 aagttcatga gtaaaatcta taagaaaaat tttgttagat ataatctata ttgctggtca
    16801 gcaactttgt tgttggccgg caatattact acgatctggc tttgttggca gcaaagcgca
    16861 ccattgtttt atttattaag tacattatta tcggtaatta cactgttcct agtctttgca
    16921 atgttgaatt gggtcgtgat caaaagtctt gggttgtgga tgatgggaga ccgactgatt
    16981 gactatttgc ttttcacagc aacgatgttg ccaacggtag tcatgcaagg cttggtgctt
    17041 ggaatttatt tccgaatatt gatgattttg cctgtgattt ttctgtttgg cggaacagct
    17101 gtaacggtaa tattgattag taaattaact gaaagagcgt tagcaaagtt gccttgtcag
    17161 atacaatcgc actaattttt tcacaaaaag gagtatttct ttctatgaag ttaactgata
    17221 aacaagtagc taatatagcc tttatccagc aacttgagat tccattgaca caaaaagatg
    17281 aagaacaaat agacttgatt tttactgaca caaaggctaa tgtgcgacaa atcaagatta
    17341 ctaaaaatga gcagcaacga atttgcttgt cttattcaca tgaagacttg ctgtatcgag
    17401 gattgtttat ctgccttcca cgttttttag ctcaaggagg agagatgcca tacattgaag
    17461 aaacctcgat cattgagacc agttattcat tagatgcttc tcgtaatggc gtgatgaata
    17521 aagagactct aaaaaaattc atttcttact tagcgttgat ggggtacaac acattgtata
    17581 tttacacaga agatacctat gaagtagaag accttccata ttttggttac cttcgcggag
    17641 cgtatacaaa agaagaagtg aatgaaattg ttgaatttgc ttctggtttt ggcatagaag
    17701 tagttccatc gatccagacc cttgctcact tgacccaatt tttgaagtgg tatgctcaac
    17761 aagaactgat ggatgatcaa aatactctac tgatcggtga agaaaaggtt tatgcggcaa
    17821 tcgaaaagat gattattgcc tgcaaagaaa tgtatcagac agagcgtatt catttgggaa
    17881 tggatgaagc ctatcaagca ggtctgggac gatatttaag cctgtatggg tattgtgatc
    17941 ggacaacttt aatgattcaa catatggacc gtgtgttatc aattgttgat aaatataaga
    18001 tgaaaccaat gatttggagt gatttcattt ataagctatt agatgaaacc ggtaaagata
    18061 ggtattacaa tcctgatttt aaactcaaag cattagcagc taaaggatta ccagcaggat
    18121 taacctatgt tcattgggac tatggttcag atgaagtttc ctcctatgag aaagtaattg
    18181 ataaccattt gaaattttgt gacattgatc attacgtttt agctagtggt gcccatatct
    18241 gggggagact agccccgaat catgggaaaa cagaagcaat tgtttctgca gctgtaaaag
    18301 cttctaaaaa taaaggtgta cgttctgtga tgttaactac ttggggagat gaagggcagg
    18361 aaacagagca ttggcattcc ttaattgggg cattaaaatt agcagattat gtctattctg
    18421 aagaagagtg gaatgatttt gaggaaatct acgatcgttt attaggaaca ggtagttatc
    18481 aattaatgtc cgaattacga tatttcgatg aagtggatac cattacaaat aacaacttac
    18541 aaatggcttc cgtgagtaaa ctgctacttt ggcaagatcc gttagttggt atatatgact
    18601 ttcatgtagc cgctcataac aaaattgcca ctagaacaat tggtacttat tatcatgagt
    18661 tagctcagaa attagatatg aataaaaatt ggaatccaaa acaaccaatt ttaacaacta
    18721 ttcgtcaacg atatatactt ttagctgaaa ttttagcaca aaaggcagaa ctaggcatct
    18781 atttacaaca ctgctgtctg gtagaagacc ttgcaggatt aatggaatta gcgaatcggt
    18841 gtgaagcact agccaatcga gtaaatgaat tggcatctat tcatgaaata atttggtatc
    18901 aaacatacaa aacctatggt tgggaagtat tagaacaacg atatgctgca ttagctcatc
    18961 gtctgaaaac cgttgcgcgt cgtattaaaa atcatcttca ggggcaagat gccctagagg
    19021 agcttttgga agaacgatta ccgttttgtc aatatcaagt gccgcttgaa atttctggct
    19081 ttaattatcg gcaaagctcg gtgtcaggct acaattaacg aaggaatctt cccgttgaac
    19141 ggaccacttg ctcatctaat gggaaagtgg ttcgttttct attcataagt agcttaccac
    19201 taactctttt attaagaaga gaaaaaaagt aggaagtgag aaaatatgtt atcggactat
    19261 tatcaaaatc tgtcagttat aagtgtcaat acagaaccat tacgtaatta ttatattcct
    19321 tatgcaagta aagaagaagc aaaacaagag ttagaaaggg aaaaaacgag ccagtttatc
    19381 gatctcaatg gtacatggga ttttcagtat tatccttctg tccaacagtt accggaaaat
    19441 ttttttcaag aggcctttac tgaaagctat gatagaattt ctgttcctgg agtttggcaa
    19501 acagagggat ttgacttacc tcagtatatc aatgtatctt atccaattcc ttttgatccg
    19561 ccttatgtac ctaatgatac cccttgtggt gtatatcggc gtcagtttca aattgagcaa
    19621 acagatgcac gcttttactt aaatctagaa ggagcagata gtaattgttt tgtttggata
    19681 aatagaaact ttgtaggcta tgaccaagtg agtcatagta catctgaatt tgatgtgacc
    19741 aagtatttac aggttggggt taatgaaatt caaattctag tgatgaagtg gtgtgatggt
    19801 acctactttg aagatcagga taagtggcga atgagcggtc tatttcgtcc agtgtatctt
    19861 cttcaacgac caactatgca tctgacaagt tatcaactac ggacgttgac tgatcctaaa
    19921 aaaggaagcg gaacattaat ggtttctttt caacgattta ctcctattga agtatcgtta
    19981 cctatttctt acgaattatt ccatcctgat ggacgtctca tagcgaaagg ggagtgttac
    20041 tcggaacaac aaataaattt ggatgttgaa gattgccttt tttggacagc agaaacgcct
    20101 aaattatata cattactttt aacatgtaat ggtgaatatt ttaaagaaaa agttggcttt
    20161 cgagcactga cgatcaagaa tcgtaagtta ttgctgaacg gaacacctat taaattatat
    20221 ggagtcaact atcatgacgt gaatcagcaa ggcacgccag tgatgacccg agagcagtta
    20281 cgtgcagatt tgttattaat gaaaaaatta aatgtgaata ctgtacgaac ggcacattac
    20341 cctaaatcac cagattttta tgaattggcg gatgagattg gtctgtatgt aatcaatgaa
    20401 gcagatttgg agtgtcatgg tgtggttaat ctatatgata ctgaagcgaa ttatcaacta
    20461 attgctaatg atccgacatt cgaaaagccg attatggacc gagtgatccg ttctattctt
    20521 ccttatcaaa atcgaagctc tatcattatg tggtctatgg ggaatgaatc tggttatgga
    20581 gtaaattttg aaaaagctca agctttagca cggaaattgg atgattcacg gttgattcat
    20641 aatgaacgct cgattgaacc agttattgac caagtgaatg attttagtaa cttggatgtt
    20701 attagtcaaa tgtatccccc actggaagat gttcatcgtc attgtcaaag aagtgatact
    20761 gaaaaacctt tttttatgtg tgaatatagc cacgctatgg gcaacggtcc tggagatctt
    20821 aaaacgtact tcgatttgat tcaacagtat gattcctttc ttggcggttg tgtctgggag
    20881 tggactgatc atgcaatcaa tagaggaact ttagaaacgc catcttattt atacggtggt
    20941 gattttggtg aaaaatatca cgacggcaat ttttgcgtag atggtttatt gaccccagat
    21001 cggcaattaa cagtaggtgc attggagtac cgtaatattc attcgcctat tcaactgatt
    21061 gctgtagatg aggagctgca agaagtaacc ttgagcaata taactgcttt tacagccggt
    21121 tcagcattta acctttctct tgaatggtat atagatggaa aaaaaacagt ttatgaagta
    21181 atgaatcctt tcatacttga gcctggcaaa agttgttcat tgcccatcac agtacctaca
    21241 acgattcatg gtgctcatac ggttgctgtt tcgctatctg tttataaaaa tgatgagctt
    21301 tatggacagc aacagctctt tcttaaaaaa gaaaaaatga gattgccaag aactgctcat
    21361 cataatgatg caccacaaat ttcagtaaaa ggcacagagc tgataatcaa aggagaatcc
    21421 tttatttata tatatcaatt agcaaaagct gcgttcactt ctgtaaagat caatcaaaag
    21481 gaacttttgg aacgtcctac tcaattttca atttggcgtg caccaacgga taatgatcgt
    21541 aacttagtaa acaaatggaa agcagctgga tatgctgaaa tgtctttaga aatcagaaaa
    21601 aaagactgga aattcgtaga tgatcatctc ctgatcgaaa cgtcttatcg aggagttatt
    21661 ccaggattac agccaatttt tacaatgcac atacagttga aaataaatgg tgcaggcgta
    21721 atcaaccaaa aagtatcagt ggagaaaaat ccgatttttc cagatttccc tcgctttggg
    21781 atggactggc cgttgaatga tactttttcg aaggtttctt attgtggcta tgggccgtat
    21841 gaaagttatc ctgataagca ctatgctgcg atgtttggta tttatgagat ggagattgag
    21901 gaatttgatc agccatatat caaaccacaa gaatatggta accgctggca atgtgattgg
    21961 gtatcaatca aaaatcatca aggatctacc atgacggttt atggaaactc taatttttct
    22021 gctctgcctt atagtcaagc tcaattaacc gaaaagtcac accattatga attaataaaa
    22081 gaaaatagaa cttggttcaa tttaagttat aaacaaaatg gtatcggctc acacagttgc
    22141 ggtccttatt tagaagatcg tttccgtttt atggaagata cttttgactg gaatatagtg
    22201 attactttca aaggagaaaa tagatgaaag aaacaaagat caatcaagtc aaaaaaaaat
    22261 tatctcgtta tcaagaagtt gtttatcgaa accattgctt aaaatggtca aaaaataagc
    22321 tgaatgttcg ttttaatgga ttattttatc gtttcgaaca gttagaagaa gtctggaaac
    22381 cggtaacgaa tttccaatca tgtcctgtac agctcataaa tgatccaaaa gaaacatacg
    22441 atttatgtat aacacacctt tataaccagc atttgaaaaa tgacggattt tatttaaagg
    22501 ttactaatga caatcaactt acgattgaat cagcaaacct tcgagggttt caatatgcta
    22561 tggaagcctt attagagagt tttttttcgg taggagatca attattatta ccggaattga
    22621 ttctgaaaca tgaaccatca gtgaaaattc gaggaatcat tgaagggttt tatggtatcc
    22681 cctggacaca tgaaatgcgc ctctctcttt tttcatatat gaaagataac caattgaata
    22741 cttttatgta tgcccctaaa gatgatgaat tattacgtaa aaaatggcgt gaactctacg
    22801 atgcgcaaga attagacaaa tttaaggagc ttttatctgc tgctgaggct agcaatatcg
    22861 atttttggta cttaattagt cctggaaatg atattgatat tacgtgtgaa gaagacattc
    22921 aagttcttct gaaaaagtta gaacaactga ttgagcttgg cgtatttcaa tttggtctat
    22981 taatggatga tattgactat caattaaaag gtgctgctaa acgccgtttt cgagagccag
    23041 cattcgctca tgcctattta gtgaatcgag tagaggaata tcttagcact cggttgtcca
    23101 atcatgaatt agtcatttgt cctacagaat atgataatcg tcatggttct cgctatttag
    23161 caacgttaag tcaagaaata ccagaacaat taccgttctt ttggactggc ccaagcacgt
    23221 tagcggcgtc aatttctaca gaagagctgc aggaaatggc ttctgtctat caacggccga
    23281 tgctgatttg ggataatatt ccggtaaatg attatttaga ggataaagaa ctattgttca
    23341 tgagtccata tgagaatcga acaccgaatc tttctaagga gagataccag gttacaggag
    23401 tagtttcgaa tccaatggct caattagaag cttcaaagtt tacgatcaat agtatggcta
    23461 attacttatg gaactgtgag cgttttgatc ctttggaaac ttggacgtca gtcgttgaaa
    23521 aagtagttgg aagtaaacta caaccagctt atcttacctt aaccaatgct tttccaaatc
    23581 attacacaag cagtctgctt tcagatgaag aattactgct agccaaagac ccagaatggg
    23641 tcacaaaaga aatggctgct ttagtccaag cagtaaaatg gatccagcaa gaacaacata
    23701 catctagatt gagaacagaa ttggagcctt ggttacaagc aatcacagaa agttggactt
    23761 tctggcaaga atggcaatta aaaaaagatc caaaagaagc agaagaatgg ttggctaaga
    23821 aaaaaacaca ccgcatagga cgtgatttag taactgccca tttagagcaa attatcaaaa
    23881 gttagatatc ttaaaaaata aaaagcaaga aaaaggagaa caaaatggtc aagagattaa
    23941 ttagtgcaaa ctacagtgat gtcaagaaaa tgacgtcaaa agagttgaag caatccatca
    24001 aagcgagtga aggacgggtg attgtttgtg aaacggttgc taatactctt ccacaatctg
    24061 gagaaattac gaatgcagaa gttgcgtcag catttggtgc agatttgatt cttttaaatg
    24121 gtttcgattg ttatcgtcct gcagtttttg gactaccaaa tgtgacgatt gagaaggttt
    24181 ttgatctaca gcaaacgatt gaaaacccga ttcctaaatt aaaagaacta gtcggtcgtc
    24241 ctgtgggaat taatttagaa cccattgccc ctaaaacaaa tatgatgagt gagaaagtag
    24301 aaatcagcca aggaagagca agctctgttg aaacgataca aaaagcagaa gaactaggag
    24361 tcgattttat ttgctttacc ggtaatccag gcactggagt aaccaattta gaaattacta
    24421 aatccgtaaa aatggcaaaa aagtattttt cgggattgat tattgctggg aaaatgcata
    24481 gcgccggctc agaagagcca gttgtgaata aagaggcgat tatttcttat gcggaagcag
    24541 gcgcagatat tttactagtt ccttcagtag ggtctatccc aggcttttta gagcaagacc
    24601 taattgaagc ggttcggttg gcaaaaaaat atgatttgtt aacgatgtct gcaatcggta
    24661 ctagtcagga aagtgcccga ccagaaacat tgcggcaatt agccattatg aataaaagtt
    24721 gtggtgttga tttacaacat attggagatg ctggatacgg gggattggca ccagcagaaa
    24781 atattttcga aacctcggtt gcaattagag gaatgcgaca taccatcaac tgcgttagcc
    24841 gctcgatcaa tcgctaacaa aattaaataa aaaatggtta aattgattat ttaagtggga
    24901 acatacttga gatatcagct aacttctgtc actttaaaaa agggactgtg acagaagtga
    24961 aaatagacaa aaaatatccg aacaagagac taggatagca gaaaaactat cgttttgcaa
    25021 cgaggaccaa ctggaccgta ggagcaattc tcttattgtt cggatatttc gcttgttcaa
    25081 ggacttatgt ctgtagtgcc cttttttggt aggaaaaatg gtagggaacc atatcatttt
    25141 taatgaaaat caagcatttc aaaagttgaa aagtaagcgc cccatagaac agtacctgta
    25201 cgtcaaataa cccgacctat agaatagaat cgggaatgtt tggcgttttt agttacgaga
    25261 aaaatgttgt tgtacatcct tgttccaagg caacagttga tctaaagttt ctgctgaaag
    25321 tacgggaaga tttggtatct tatcaaatag aaactctaga tactttacag gattcaatcc
    25381 gttaagttct gctgttttat atacactcag aatgattcct gaagttcgtg ctccttcaag
    25441 acttgtggaa tgcaaccaat ttttccgtcc tatcaccagc tctttgatat ttcgctccgc
    25501 acgattattt gtgagttcta aacgaccatc ttcaaaaata ggttcaaaac cacttcgtag
    25561 tttacacgca tattgaacgg ctgcatccaa cttggatttt gcaacaggat ctatcgttgc
    25621 catccactca taaaaagcaa taaataatgg acgcagttct tgttgccgac agcttaatcg
    25681 cttctcagga gaaaagtctt tccatttctt ttctaggaca aaccatttat ccaattgttt
    25741 gactgcttga gctgcgggaa tatccgtgtt tttctttcct tttggaattg cttcgaaaaa
    25801 tttccgccga acatgcgcga aacaatagac aagtcgtaca ctttccacgg cattataccc
    25861 gctatagccg tcacagtgta aataccctgt aaactccttg agaaaagttt tcggaacatc
    25921 tccagcacga ctttcgtcgt ggtgataata aacgatggga tgctgactgt cttttcctgt
    25981 acaaaactgc cagtaatagg tatctgtttt ggcactttca atcacacgat aacttgtttc
    26041 atccccgtgt agaatctctt cttgattaag atagactctt aatcgttctc ctaaagggtc
    26101 taacgcgttt tgcactgctt taatatgcca attggtgata ttatctctcg aaatatccaa
    26161 cccatgtgtt tgtttccaat agttctcttg ccgataggca ggaactttct gaccaaattt
    26221 catccggatc gtttccgcca ctaaactatt ggaacctaag ctattagaaa tcaaaggttt
    26281 aggaacgatc gcttttttaa aagaagaaag tccttctttt tcgcagcttt tacaacaata
    26341 ggtatgttga taatgggtga gacaatccaa catagcctga tggaaacgaa tttcttctcg
    26401 tacttttgtc cgtccgatat ctttcatctg tgaaccgcaa tgttcacaaa attgttcttc
    26461 caaaggaagg agatgttctt tctctgttat aggtaagtgt ttgattttgt ctgctttcgt
    26521 tcctacaact cgttgatgtc cttttactgg aataatggtg gcagctgctt ctggaacact
    26581 tacagaaatt tcttcatcac taaaaagatt caattgccca ttcgtttcct caaagagagt
    26641 ctctttagag cgtccaaata atttgttggt taaataattg accttttcat tcaatagttg
    26701 gatttcagtt gtaagattct gaatggtttg ttgttgtgct tgattggttt tatgggcttc
    26761 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
    26821 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
    26881 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
    26941 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
    27001 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
    27061 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
    27121 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
    27181 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
    27241 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
    27301 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
    27361 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc
    27421 atttaattta tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg
    27481 catttgttag taaggtactg ttctatgggg cgcttacgtt gaaaaacgtt gatttatcgg
    27541 cattccccat ccatattata tttacgtctt attcccactc aatatgagta gcctcgtaaa
    27601 gaagctatta tatcagtgct ttttcagcct attcctcatt ttggtaggga aatggtaggg
    27661 ttagattttt actgcttgat ttccattaaa gtttgcaact ttagattttg ttgcacaggt
    27721 aaatttaatg tttcctgtca tttgttctgc aattccttca tcattacggc tccatagatg
    27781 agcgtagtgc tttaaagtga tttcagggct agaatggcct aaccgttgcg acacgaccag
    27841 aatgtctgcg ttaaactcat tgattaggta gctaacatga gaatgacgta atccttttcc
    27901 ttgtattagg ggtaccttag ctagtttggc ataacgctga ataattcgtt gaacagttga
    27961 acgatagagt gggaggtcag tgtagctaag aataaattgt tctacaccat gatttttttg
    28021 aataactttc cactttttta gcacttcaat tgtatcatcg tccagagaaa tgatccgcaa
    28081 gccgctttca gtttttgtgt aaggtttccg aataaaatct ttttgatttg tcatttccaa
    28141 ggtgtgatga accctcaact ttttacgttt gaagtccacg tcattccaat taagtgctaa
    28201 tccttcgctt acacgaacac cagtcatgta atatagccag atcattaaaa aacacatatg
    28261 ttcgtagaaa tcatctttat aaatttttgc caaaacttct tcaaattctt cttttgtcca
    28321 gtaaggaacg attgattttc cttttggaat tgcttttgtt cttttggaaa tattctcatt
    28381 cagaaattgc agggtgaccg catagtctaa tgatttacga aacataccgt acataagtga
    28441 actgtatgct tgtgagtatc cgctatcgtt caataaccaa attcgataat tttcacaatc
    28501 tcgcacattg atttcacgaa gcttcttatc accgaaaaat tcagtaatct gaatcaatcc
    28561 acactcacga gaactccaag tacttttttg tacgctagct ttgtagtgtg gaacgtaaga
    28621 ctgctccata aattctttgt aagttaaatc ataattcgca aatccattta caaccatgta
    28681 ttcatttttt atacgcatga cttctttgtg tgcttcacga gctgatgaga atcgttttcc
    28741 tagagaatct tttgttcctt tcttctggat cctctttcca gtcacttgat ctgttcctaa
    28801 ctcaactaga taagaaaagc gaccattttt atcttgatac acacaagggt attttgtttt
    28861 catagttatt cctcctgtga aagaggaaca cctataattt cttcaattac ttgtcggggt
    28921 actaccccaa ctcttttatt attataatat ggatatccct gatttaccat tcttgttttt
    28981 gcttgtcgga ttattgtggt agcttgatgt gttttaaatc ctagagcctc taaatctttt
    29041 cgacaaattg tatttttcat tgtataaact cactttcaaa gaaaacacta tcattgggta
    29101 atagtgttat ttctttattt ttgtataatg aacggtactt tcttgaaaat ccatcacttg
    29161 ttcaggactt cccaactcat ttaaagctaa agcattgtaa aaaaatggac gtctaactat
    29221 atattcgctt gtatatagta tatcttgatt cgtggaatca tagggtttct ttaccatctt
    29281 tttggtgaca gttggtagtt tgagattccg ggacttgaaa aaagcttttt tcttatgctc
    29341 tttcaattcc agctctttat cgaaatattt gctgatatag cgcccgcgat tttcgatact
    29401 gtctacatcg atcttgttga tcttaacgaa accctgaccc caaatcgtag ttaaccggtt
    29461 aaatgagata aaggggaaat caaacaagat aatatggtag tggattgcac cgcgttgctg
    29521 cttttcccac gtggcgagat actttaaatt tgctttttta gttttataga ggtcataatt
    29581 cagtcgtttg ataaattttt taaattcatt atttgcatac tcaatgtctt gaatgttttc
    29641 tttgaaagtg agagttaaaa atttcgtttg attgtcaaaa ttcgtgtcta caaggcgggc
    29701 aatctcaaat cgcatacttt gataatgttt ctgtttgcgt tttaaactgt catattgtcc
    29761 ttgagcggat aattcatcat agttttttct tttttcaaga gtaatatcat tttcataaat
    29821 ccaagctaat ttttgttttc gttccagatt tacttcgttt tcgatcgttt tacgtttggg
    29881 agtaatgatt gcttcataat cataaatttc aatatacgtg ggagtttcaa tgattttctg
    29941 attataagct tgcaaaaatc atcactcctt gttgcgtatt cgattgtcaa agaaccagtc
    30001 attttctcct gatgttgatc tataaatcaa gttaaggggg aaggcctgcg tagcagccct
    30061 tctagcctat ggggtgttgg gcggtcttaa cggacagaaa cggctctgtg ggcgctgccc
    30121 cgccgtttcg tcctaaccac ccaacactcc atagtatagt tagttttgtg tagtggtacc
    30181 ttgttttctg ggaatcaaag ttgccgtatc agcggttgcc gataacccat aactgacaaa
    30241 ttgtccattc gagcgtcccc aaggtacaat caccaaattg gtaaatgtaa ttatggctaa
    30301 accttgttgg gtaagttctt ccggcgtgat cacaggatgt tcagatttga ctttgacact
    30361 gattttttcg tagcgaagtt ttggtaggat acattcgtag ctccaaccta gaatttcgcc
    30421 ctccttttgc cagcgagtga cattgacgac ttggtattct ttttcgagtg tttcttttgg
    30481 taaactgaga tcggtaattt ttattggcat cacaattctc cttttttata cgaaagttta
    30541 tacgatttga ttaaaaaata tagatggcca tctacgactt gtattatata cgagaactta
    30601 tacgtagtca agagattttc taaaaaaata tatacgattt tttatacgag tgttataatg
    30661 aaaaaaatga taaggaggaa tttgaatatg tttggtttag tacaacctaa taaagtgaag
    30721 gtgggccaac gaatcaaaga aataaaagac ggaatgtctc tctcttttac agaattaggg
    30781 aatcgattag gtttaaaaaa gccgacgatc agttcctacg ttcaaggcta tgcgttggct
    30841 cctaagagtg tgatcaacca attatctagt atcagcggaa aacctgtcgg ctggttttat
    30901 tttgggcatg tggaagaata tatccgagag tatttgtttc tcattggtca gaaaaaaata
    30961 gtggacgatt atcctgaaat cattgagaaa ataaagcaag aattttatac gggcgagttc
    31021 aaaaatcctg cttgggagaa tgagctaggc tatcctttgg aggaatttat ccaagaatgt
    31081 tttgtagaat attcgagtga aatcatgaag gactatgtcg tacagattac gaaagaggta
    31141 cttgaagaat ccaaaacgct aaacaaacta tcatcaaaag caaaagaaga agctgtcacg
    31201 attctttcat ctgggatcat tgactatatc gagatgagtg gtgagatcaa gtatggagag
    31261 aaagatcgca ttgcgaaaat ggtgaaagaa tcaataaaaa cctttgatgt gaaacaagac
    31321 ctgacattta atgattccta tttgattgga aagttgatca atattcttgg tacagatgaa
    31381 gatacggagc tgtttctttc ttctttatca atgatattta ctgataagca tttttccact
    31441 cgatttggtg gggaagaatt agtcgaaata tttcaatcga tgcgaccagc gttaatcaaa
    31501 ctctatcggg agaaaacacc agatgaattt tatgattggt ttgagaagta aaataagaaa
    31561 agtggcttag attacaagtt ggtgaaaaaa tttttttcag cataacatca gtaatctata
    31621 aaggggttgt tgattatact gtagaagtta agtactcaag agattttttg tacgtaaaca
    31681 aagcaaaaaa gggtgcagtt tcactagaaa atgtactctt ttttgtgatt tttcttagtt
    31741 atagagtttt tttgaaact
//
LOCUS       DAZAOD010000016        31290 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000016 DAZAOD010000000
VERSION     DAZAOD010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.017"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..372
                     /locus_tag="ACHDPO_000889"
     CDS             4..372
                     /locus_tag="ACHDPO_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFN3368534.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            552..1493
                     /locus_tag="ACHDPO_000890"
     CDS             552..1493
                     /locus_tag="ACHDPO_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFN3368535.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1562..2293
                     /locus_tag="ACHDPO_000891"
     CDS             1562..2293
                     /locus_tag="ACHDPO_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFN3368536.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2437..4617
                     /locus_tag="ACHDPO_000892"
     CDS             2437..4617
                     /locus_tag="ACHDPO_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFN3368537.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4637..5119
                     /locus_tag="ACHDPO_000893"
     CDS             4637..5119
                     /locus_tag="ACHDPO_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFN3368538.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5135..5896
                     /locus_tag="ACHDPO_000894"
     CDS             5135..5896
                     /locus_tag="ACHDPO_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFN3368539.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6027..7361
                     /gene="murC"
                     /locus_tag="ACHDPO_000895"
     CDS             6027..7361
                     /gene="murC"
                     /locus_tag="ACHDPO_000895"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFN3368540.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7668..8153
                     /locus_tag="ACHDPO_000896"
     CDS             7668..8153
                     /locus_tag="ACHDPO_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFN3368541.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8146..8829
                     /locus_tag="ACHDPO_000897"
     CDS             8146..8829
                     /locus_tag="ACHDPO_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFN3368542.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8955..11600
                     /gene="polA"
                     /locus_tag="ACHDPO_000898"
     CDS             8955..11600
                     /gene="polA"
                     /locus_tag="ACHDPO_000898"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFN3368543.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11645..12481
                     /gene="mutM"
                     /locus_tag="ACHDPO_000899"
     CDS             11645..12481
                     /gene="mutM"
                     /locus_tag="ACHDPO_000899"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFN3368544.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12445..13074
                     /gene="coaE"
                     /locus_tag="ACHDPO_000900"
     CDS             12445..13074
                     /gene="coaE"
                     /locus_tag="ACHDPO_000900"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFN3368545.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            13126..13458
                     /locus_tag="ACHDPO_000901"
     CDS             13126..13458
                     /locus_tag="ACHDPO_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFN3368546.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13770..14261
                     /gene="nrdR"
                     /locus_tag="ACHDPO_000902"
     CDS             13770..14261
                     /gene="nrdR"
                     /locus_tag="ACHDPO_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFN3368547.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14284..15657
                     /locus_tag="ACHDPO_000903"
     CDS             14284..15657
                     /locus_tag="ACHDPO_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFN3368548.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15657..16583
                     /gene="dnaI"
                     /locus_tag="ACHDPO_000904"
     CDS             15657..16583
                     /gene="dnaI"
                     /locus_tag="ACHDPO_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFN3368549.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16712..17152
                     /locus_tag="ACHDPO_000905"
     CDS             16712..17152
                     /locus_tag="ACHDPO_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFN3368550.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17296..17997
                     /locus_tag="ACHDPO_000906"
     CDS             17296..17997
                     /locus_tag="ACHDPO_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFN3368551.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17994..19115
                     /locus_tag="ACHDPO_000907"
     CDS             17994..19115
                     /locus_tag="ACHDPO_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFN3368552.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19130..20362
                     /gene="pepT"
                     /locus_tag="ACHDPO_000908"
     CDS             19130..20362
                     /gene="pepT"
                     /locus_tag="ACHDPO_000908"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFN3368553.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20494..21402
                     /locus_tag="ACHDPO_000909"
     CDS             20494..21402
                     /locus_tag="ACHDPO_000909"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFN3368554.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21437..21709
                     /locus_tag="ACHDPO_000910"
     CDS             21437..21709
                     /locus_tag="ACHDPO_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFN3368555.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21720..22766
                     /locus_tag="ACHDPO_000911"
     CDS             21720..22766
                     /locus_tag="ACHDPO_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFN3368556.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23017..25626
                     /gene="clpB"
                     /locus_tag="ACHDPO_000912"
     CDS             23017..25626
                     /gene="clpB"
                     /locus_tag="ACHDPO_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFN3368557.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25777..26463)
                     /locus_tag="ACHDPO_000913"
     CDS             complement(25777..26463)
                     /locus_tag="ACHDPO_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368558.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26441..26935)
                     /locus_tag="ACHDPO_000914"
     CDS             complement(26441..26935)
                     /locus_tag="ACHDPO_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFN3368559.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26955..28175)
                     /locus_tag="ACHDPO_000915"
     CDS             complement(26955..28175)
                     /locus_tag="ACHDPO_000915"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368560.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28322..30157
                     /gene="lepA"
                     /locus_tag="ACHDPO_000916"
     CDS             28322..30157
                     /gene="lepA"
                     /locus_tag="ACHDPO_000916"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFN3368561.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            30353..31264
                     /locus_tag="ACHDPO_000917"
     CDS             30353..31264
                     /locus_tag="ACHDPO_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3368562.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
BASE COUNT        10567 a         5496 c         6713 g         8514 t
ORIGIN      
        1 cagatgttta cgaatgaaat aaaaatcatg ctttatgtgg acgatgtaga aaaaaatgca
       61 acgttttgga gagcagttgg ctttgcggaa aaagatcgtc aagaaatgga tgggacgctt
      121 ataattgaag taggagttga ggacagtcaa acctcatttc tgttatatga tcgagcattt
      181 gttgagtccc attcacctgg cacagctact agtgccccat ctttgatgtt ttacagtaaa
      241 gatatctttg gactatataa aaaaatgcag acgcaatcag tcacattagg tgatatggta
      301 cagcttggag aagaatatgt ctttaacttt gctgatcccg atggcaacta ctttgcggtt
      361 acaggtaaat aatagaaata aagactttgt ttttctgtgc gaaacaggaa agcgaagtct
      421 ttttaattca aataataata ttatgtaaac aaaaaacttt ccatgcgtaa ttatacacaa
      481 gcaaataaat cgtcaaatgc gaacgccttc tttatactgt ttaggaacga aaagaaggaa
      541 ggaagaaata catggattat caagtactgc tttattacaa ttatacaaaa atcgaagaac
      601 cagaggaatt tgccaaaaat catttagcct tttgcaaatc tttggatctt aaaggtcgta
      661 ttctagtagc tgaagaagga ataaatggta ctgtgtctgg aaccgttgaa aacacgactg
      721 cctatatgaa agcaatgaaa gctgatcctc gatttgctga tacgatgttc aagatcgatc
      781 caagcgaagg acatgccttt aagaagatgt ttgtaagata ccgtccagag cttgtaagtt
      841 taaagctaga agaggacatt gatccaaacc aagtgacagg tgcctatctt tcaccgcaag
      901 aatttaaaga agctatttta gatgaacaga cagtggtgat tgatgcacgg aatgattatg
      961 aatatgactt gggacatttt cgaggggctg tacgcccaga tatacgcagt tttcgagagc
     1021 ttccagactg gatccgcgag cacaaagaag aatttatgga aaaacgggta gtgacctact
     1081 gtactggtgg cattcgttgc gagaagtttt ctggttggct tgtccgtgaa ggattcaaag
     1141 atgtcggaca gctgcatggc ggtattgcta cttatggtaa ggatcctgaa gtccaaggag
     1201 aattatggga cggcaagatg tatgtgtttg atgaacggat cgctgtcgat atcaaccaag
     1261 tagataaaca aatcgtcggt cgcgactggt ttgacggaac accatgtgaa cgatatatca
     1321 attgtagcaa tcctgagtgc aatcgtcaga ttcttgcttc cattgaaaat gaagaaaaac
     1381 atttaggagc atgtagcata gagtgtgcga aacatccgcg caatcgctat gttcaagacc
     1441 atggaatctc tccagaagaa gcagaactgc ggtttacagc tttaattaaa tagaaaacaa
     1501 tagttttgat tgtcgaccat ttccaatatg cgctatacta gcgttgagga tggtgatcca
     1561 catgaaatca ttgatttatg ctattgggga tgtccatggc aaacatgagc tttttgaaaa
     1621 acttattcac tattatgatc caaagatcca tcagcttgtt ttattagggg atctcaatga
     1681 tcgaggtcct cgtacaaaag aatgtttttt attaggaaag caattagtcg aagaaacagg
     1741 agccatttac ctccggggaa accatgaaga atattttttg caatttctgc aatcaccgga
     1801 ggactggtat gcgccttata tgagaaatgg tggaaaagaa acgtttgaaa gcctgattca
     1861 cccaggggca tcggaggaat actccccaac tgaaatctcg atgatgatcc aatcgagata
     1921 ttcagaactg attaaatttt tagtccagcg ccccttgtat tatgaatggg aaaattatct
     1981 ttttgtccat gccggtgtgg atttgacaaa gaaagactgg cgtaagacaa gtctaagaga
     2041 ctttatttgg ataagggaac catttcatga agggaaaaac aatacaggta agacaattgt
     2101 atttggacat acgattacac caatgctcca tggagatatg cagacaacag acctctggat
     2161 tcaggatcat aaaatcggaa tggacggtgg ggctgtattc ggagggtcat tgcatggggt
     2221 tgtttttgac aaggaaggta ttcttcaaga tattgaatat cagaacaacg aaggaccttg
     2281 gcatggaatc tgactaatgg aaagaatgaa ggagctgtga ctttgttgcg gctcttttta
     2341 tttttataga gaatattgtt tctttcagta gtttaaccca ggataaaaag tatgatagaa
     2401 taaagaagca atttttagca gaaaagaggc attttaatga cggaaaattt gaaccagacg
     2461 atcattcagc ttgtacaaaa agaactttca gactatcgtc ctaagcagtt gactactgta
     2521 cttaatttgt taaatgaagg aaacactgtt ccttttatcg cgcgttaccg aaaagaaatg
     2581 actggaagtc ttgatgaagt ccagattcgt gaaatcgaag agcggtatgc ctatcttgaa
     2641 aacttagaaa aacgtaaaac tgaagtgatt cggctaatcg atgaacaagg gaaactgact
     2701 cccgagttag aagcagaaat cacccaagcc gtgaaaatgc aacaagtgga agatttgtat
     2761 cgtccataca aacaaaaacg acggacaaaa gcaacgattg ctaaagaaaa aggacttgaa
     2821 ccactcgcga agtggctgat gcagcttaca gatggagagg tgcaatctga agcagaaaaa
     2881 tatattgaca aagaaaaaga agtctcttct gccgaagaag cgttgcacgg tgctcatgag
     2941 attattgctg aacaagtcag cgataatgca aaatttcgga cttggattcg gtcttatacg
     3001 tataacaaag gtatgtatgt cagcaatgtc aaggatgagc aagcagatga aaaaggcgta
     3061 tatgaaatgt attatgactt tgcagaaccc gtccataaaa tggtttctca tcgaatatta
     3121 gctactaatc gtggagaaaa agaagatatt ctgaaagtat tctttcaagt agatgaagca
     3181 gcaattttag cttacttgga tcgccaaata gtcaaaaatc ctgcctctcc ttcttcttca
     3241 ttcgtcagag aagcctatca ggatagttat aaacgcttta ttcagccagc aatcgagcga
     3301 gaactgcgca atgaattgac tgaaaaggca gatgagcaag caatcgctat tttcggcgaa
     3361 aacctccgta atcttttgtt gcaaccgcca ctaaaaggta aagttgtcct gggatttgat
     3421 ccggcttatc gtactggatg taaactagca gtcgtagatg cgacagggaa agttttagca
     3481 atcgaagtta tttatcctca taaacctgca gcgcaagcaa aaagagaagc tgctggacca
     3541 gcttttatcc aattaattaa taaatatcaa gtagatatgg tagctatcgg aaatggtaca
     3601 gccagtcggg aatctgaact ttttgtggct gagcagttga aatccgccga ccataaaacc
     3661 tattacgcta tcgtcaacga agcaggcgct tctgtttact ccgctagcga aattgcacga
     3721 aaagaatttc cgcatctaca agttgaagaa agaagtgctg tttctattgc ccgtcgcctg
     3781 caagatcctt tagctgaatt agtcaaaatc gatcctaaag ctgtcggagt aggccagtac
     3841 caacatgacg tttctcaaaa acgtttggct gaacaattgg attttgttgt ggaaacagcg
     3901 gttaaccaag taggtgtgga tgtgaataca gcaagcccgc agctcttgca gcatatatca
     3961 ggattgaata aaacaactgc ccaaaacatt gtcatttatc gtgaagaaaa cggagaattc
     4021 accgcacgaa ctcaattgaa aaaagtgcca cgcttaggac caaaagcata tgaacaagca
     4081 atcggattct tgcgagtccc tggtgggaaa aacattttgg acaacacagg tatccatccc
     4141 gaaagttatt ctattgcaaa agaaatatta acttcagtcc aactttcaga aaaagagctt
     4201 ggtacagaag aagcagtaga aaaattgaca cgattatccg tagagaaact ggctgaaagc
     4261 ctatcagtcg gagaagaaac gttagccgat attttagctg ggctgacaca acctggacga
     4321 gatatgcgtg atgagatgcc agcgccctta ttacgtacag atgtattgag tatggaagac
     4381 ttgaaaccag ggatggaatt gactggaacg gtccgtaatg tcattgactt cggcgcattt
     4441 gttgatatcg gtgtgaagca agacggactt gtccatatat cgaaactcag caaaaaattc
     4501 gtcaagcatc ctacagatgt cgtgtcagta ggagatatcg taacagtttg gatagaacaa
     4561 gtcgatacga aaaaaggcag aatcagtttg acgatgcttt ccccttatga agagtaacaa
     4621 tgaggagtaa caaaaattga cacaagaaga actgcagcag ttagtagaag agatatcatt
     4681 aaaaagcttc cagcttcctt tcaagcacca agcaatgttc aatccacgct tacgtacaac
     4741 tggcgggcgc tatcatttaa acgatcatca tttagatttt aatgcgaagc tatttgaaga
     4801 gtcagacgaa gagacgattg caggaatcat caaacatgaa ctttgccatt atcatcttca
     4861 tctagctgga agagggtatc agcataaaga tatggatttc aagtatcttt tgaaaaaaac
     4921 aggagggttg cgctatgcac cagccttgac gaagaaacag ataaagatgg agtattatcg
     4981 atgccaagat tgttctgcca cgatctgccg caagagaaga atcgatgtac gcaaatatcg
     5041 ttgtggaaga tgtcatggag aaatcaaatg gattgagaca aaaagagaag actttaatga
     5101 agcacaaaaa atcagatgaa aggatagaag gcctttggaa aaaagtgagc agaggaatct
     5161 aaaagactgg aatcagctat taaatttttt agccgcacct gaagagggaa attttgagga
     5221 actgacggca cctacactta ttttagctgg aaactgtctt cctatcttag ctgataaagc
     5281 agcacaaatg tatttaaatg gccaagtaga tcaattgttt ttggtcggag gggtggggca
     5341 tgcgactaga atcctttatg agaattttga aaagcaagga tttcattttg aagatggcat
     5401 gagtgaaagt gaaatctgtc gtcagtatct aaaagaagtc tatgatttgc ccgataaggc
     5461 ttttctgata gaatcgaagt ctacaaattc tggagagaac gccacttttt cactggagat
     5521 tcttcattcc ttaggagctg taccagaaaa aatcttattg atgaatgatc cgacactgca
     5581 acgcaggact cgagcaactt ttgagaaagt atggcaaaat gaacaaacta ttttcgcgaa
     5641 tgctgtgcca tttgtgccgg aaatccttca cttttctgaa gagatcatct ttacagcaaa
     5701 agaactgaat catcaatggc ctaaggaata tttccatgcg ctagtattag gagaaatgga
     5761 acgtctccat gacgatgaga acggctatgg tccgaaagga aaagatttta ttcctcacat
     5821 tgatatatca gaggaagttt ggtcttctta caccagaatt aaagagtcaa taaaaacgga
     5881 tttttctcgt acttgaccat tttagcaagc gaatcctcct ttccaaataa atttggttga
     5941 aattttcaat cgtttataag ataatgagga gcgtgttgaa tgtaatagct aaaagaatgg
     6001 acgctagata agagaagagg attcaaatgg aaaatcaaaa taaattgtat cattttgttg
     6061 gtatcaaagg ttcaggaatg agctccttgg ctcttgtttt acatgaacaa ggtctaaatg
     6121 tccaaggatc agacattgaa aaatatttct ttacacaaag agatttagaa aaagcaaata
     6181 tcacgattct gccatttaac gcagataatg taaaaccagg gatgacgatc attgcaggaa
     6241 atgcatttcc tgattcacat gaagaaatcc agcgagcaaa agaattaggt ttggaagtga
     6301 ttcgctatca cgactttatt ggtcatttta tccaaaatta tacgagtatc gctgtaacag
     6361 gctctcacgg aaaaacaagt acgactggac tgctctctca tgtattgagt ggtgtccgtc
     6421 caacaagtta tctaattgga gatggaacag gacatggtga tccgcaagcg gaattctttt
     6481 catttgaggc ctgtgaatat cgccgtcatt tccttgccta ttcaccagac tatgcaatca
     6541 tgaccaatat cgattttgat catccggatt attatacaag tatcgacgat gtatttacag
     6601 ctttccaaac aatggctgga caagtgaaaa aagctatttt tgcgtatggt gacgatgctt
     6661 atttacgcaa attaaaagca aatgtgccga tttattatta tggtgtcaca gaaaacgatg
     6721 atatccaagc acgaaacatc gaacgcacaa cttctggttc tgcttttgat gtctatcatg
     6781 gggatgaatt tgttgggcac ttcactgtac cagcattcgg taaacacaat atcttaaatg
     6841 ctttaggtgt tattgcagta gcttatttcg aaaaactgga tctgaaagaa gttgcagaag
     6901 aaatgctgac tttcccagga gtaaaacgtc gattcagtga aaagatcgta gcagacatga
     6961 ccgtagtcga tgattatgcg catcaccctg cagagatcaa agcaacgatt gatggcgcac
     7021 gccaaaaata tccagataaa gaaataattg cagttttcca accccatacg tttacgcgta
     7081 cgattgcatt gatggatgaa tttgcagaag cacttgattt agctgataaa gtttacttat
     7141 gcgatatttt tggttcggct cgggaagaac aaggaaacgt taagattgaa gaccttggag
     7201 cgaaaatcaa aaaaggtgga gaagtcatca aagaaaataa tgtatctcca ttgttagatt
     7261 atcatgatgc agtagtaatc ttcatgggtg ctggagatgt tcaaaaattt gaacaagcgt
     7321 atgaaaaact tttaagcagc acgacgaaaa atgtactgta atacaattac tgcagtgtcc
     7381 ttataaaaat agaaagaggg ggagtggcaa aaatcttgcc aagccccctt ttttgcaact
     7441 tatgataaac ggtgttcaaa agcttgcatc tgcggtaata agcccaatca aatcaaaaac
     7501 atgagaagct gttttttctt ggctgttctt attatttgat gcaggacagc tttttcacga
     7561 cctctgtaaa ctataggaat ctgttaaatc aagggagcag aacttgcctt ttacgctact
     7621 tttggtacaa taatgtatga ttaaaaataa actggagggt ttctatcttg aacataggta
     7681 agccgagaaa actaggaaaa acaataaatg aaatcgagga aggcgactcg ttatccttaa
     7741 cagaatctat tgaagataac cagcttttgc tgtatttggg attgacgaat gatgcaaatc
     7801 ctttgtatat ccaacatgac tttgcacaaa aaacagaata tcaacagcca atcgttccat
     7861 cagtgatgct gatggggatc atcacaagtg caatttcaaa gcatcttcct ggaccaggat
     7921 cacatgttgt caatttttct gtcaatttta ttgaaccggt tttccattat gaaacactga
     7981 cttttcagtt tgaggtcata aaagtagata agatgaagga tgtggtgacg atttctgtag
     8041 aagcggagaa tacgaacgaa gatcgtgtgt tggatgctgt cgttatggtc caaccgccac
     8101 aagttcctga attggaaata gcaatcgaaa gtgaaggtga attgaatgaa taatccaagt
     8161 acatcaatgt caggtatcaa tcgtttttat gcaaaagttt atggattttt aggtatggga
     8221 cttgccctta gtgcagtcac ttcttacttg gctctttggg tatttccttt gcaattagca
     8281 acttttatca ataattttcc actaggcttt gtgggtctgt ggatcgttga actgatttta
     8341 gtaatggttc taggcgtaaa agcacaaaag aatccgagct tagcaatcgg tggatttatt
     8401 gcctactctc ttttgaatgg cataacatta gcggttactc ttgcatacta cgatattgga
     8461 acagtaacgc aagctttctt gacagctact ttgatgttca tggggatgtc tgttgtcgga
     8521 gtaacaacaa aaagagatct tagcggggtt ggaagagcag gacaggcagc tttaatcgga
     8581 gtgatcattg cactagtctt gaacatcttc attttgagaa gtagcgtagt tgagctgttc
     8641 atctccctac tgttagtcgt catctttgca gggattacag cttatgataa ccaaagcatc
     8701 cgtaatatct atgtccagac aaacggaaca gcacatagtg gaattgctgt attcatggca
     8761 ttgaagctgt atttggactt tatcaacttg ttcttggcgt ttctgagaat ctttggacgg
     8821 aacaactaaa aaagaaaaaa attcatcagt tggggctata ccgaattatt tggtatggtc
     8881 ccgctttttc ttttcgcatt ccgcaggatt ctttgttaga atgaataaga actttacagt
     8941 aaggagttaa gaagatgaca aaaaataaat tattactcgt tgatgggaac agtgtggctt
     9001 ttcgcgcatt ctttgcgctt cacaattctc ttgaacgttt caaaaataga aacggtcttc
     9061 atacaaatgc aatctatgca ttcaatacga tgtttgaaaa tgttatgcaa aaagagcaac
     9121 cgactcatgt tctggttgcg ttcgatgcag gaaaaacgac ttttcggaca gaaatgtatg
     9181 cggagtacaa aggtggaaga tccaaaacac ctggcgaatt caaagaacaa atgccatata
     9241 tacgtgattt gttgacagga ctaggggtac agtattacga attgcccaat tatgaagcag
     9301 atgatattat cggtactttg gcagaaaaag tagacaaaga tcaatttgat gtcgtcgtgc
     9361 tttcaggtga tcgggatttg actcaattag ctagtaaaga agtaaaagtg gatatcactg
     9421 taaaaggtgt cagcgatatc gaaagctata caccagaaca tgtagcggaa aaatatgatg
     9481 ggttgacgcc aaaacagatt attgacatga agggactagc cggagatgcc tctgacaata
     9541 tccccggtgt gactaaaatc ggtgaaaaaa cagctatcaa gctattgaaa caatatggct
     9601 cagtcgaagg aatttatgaa catatcgatg aaatgaagca aagcaaaatg aaagaaaatc
     9661 tgataaatga caaagagcag gctttcttat cgaaaaaatt ggcgaccatc aatacttcag
     9721 cgcctgtgga tgtctctatc gactcattga agtatgaagg gaaaaatctc gataaactcg
     9781 ttccgtttta taaagaaatg gatttcaatc agttcctttc taaattgaat atcgtagaag
     9841 aagaagtaaa aatggatgat attttgtttg aagtcgttca tgaattcaaa gaggaaatgt
     9901 ttactacgga tatggcgttg tacgtggaaa tgatgggcga caattatcat acagaggaaa
     9961 tcgtcggagt agcgtggggg acagaaaaga aaatttatgt cacgaacgat ctatctgtat
    10021 tcgaaaaccg agcgttccat tcttggatca ctgatccgac tcggctgaaa aaagtatatg
    10081 atgcgaaacg aacttatgtt gctttaaacc gctatactgg aaaaacgaaa ggaatcgatt
    10141 ttgatgtctt gctaggtgca taccttctcg atacgaatga aaaaagcaca gatatcgaag
    10201 gaatagctgc tcattacgga tacaacgata tccaatcaga tgaagctgta tacggcaaag
    10261 gggcgaaaaa aggtttacca gaagaagagg aactcttttt tgctcattta gcgcgaaaag
    10321 tagctgcaat caatgcgttg acaccaaaat tgagccaaga actggcagaa aaaaaccaag
    10381 aagatctttt ccggaaaatg gaactgccat tgtctatcat tttggcagag atggaaataa
    10441 gcgggatcaa agtagatgcg actcgcttac aagaaatgaa gggcgagttc tctgctcgct
    10501 taagagagat cgaacaaaaa atctacgaag aagccggcga agaattcaat ttgaattcac
    10561 caaagcaatt aggagtgatc ttatttgaaa aaatgggatt acccgttatc aaaaaaacaa
    10621 aaactggata ttccacagcc gtagatgtac tggaacagct tcgtgaacaa gcaccaatcg
    10681 tagaggatat cctcacctat cgtcaaattg caaaaattca atctacctat gtcgagggac
    10741 tgctgaaagt gatccaatca gatggaaaag tgcatacccg ttatgtccag acattgaccc
    10801 aaacaggacg attaagctct gttgatccta atttgcagaa catcccgatt cgattagatg
    10861 aagggagaaa gatacgtcag gcatttgttc ctagagaaaa agactggctg atttattctt
    10921 ctgactattc acaaatcgag ttacgcgtac ttgcgcatat ctcaaatgat gaacatttga
    10981 aagctgcctt cctagaaggt caagatatcc atgccagcac agcgatgcgt gtatttggaa
    11041 tcgaaaaggc agaggatgtc acaccaaata tgcgtaggca ggcaaaagca gtgaattttg
    11101 gtatcgtgta tggcatctct gattacggac tttcacaaaa tctaggaatc agccgaaaag
    11161 cagcacagca atacatcgat acgtactttg aaaaataccc aggtgtcaaa gaatatatgg
    11221 aaagaatcgt acgcgaagca aaagaccaag gctacgtcga aacgctgtat caccgccgtc
    11281 gatatctgcc agacatcaat tcaagaaatt acaatatccg ttcttttgcg gaacgaacag
    11341 ctatcaatac accaatccaa ggaagtgctg ctgatatttt gaaaatcgcg atgatcgaat
    11401 tggataaacg attaaaagaa acaggtcttc aagctacgat gctgttacaa gttcatgatg
    11461 aacttgtctt cgaggtaccg gaaaaagaac ttgaatcatt agataaattg gtgaaggaag
    11521 ttatggaaca agctgtttct cttcatgtac cactgatcac tgacagcagt tggggaaaaa
    11581 cgtggtacga agcaaaataa acattgttta agacagagca atataatgaa ggtgaaaaga
    11641 aaaaatgcca gaattaccag aagtagaaac cgttcgtaaa ggattggaac ggttagtagt
    11701 aggaaaaacg attcaaaaag ttcaggtctt gtggcccaag atcatcgagc aaccagagac
    11761 acccatcttt gaggcttctc ttgttggcga aaccatccaa tccattggac gtagagggaa
    11821 gtttttaatt tttcatctcg atcattgtga actgatctca cacttgcgaa tggaaggaaa
    11881 atatcaattt acgaaagaaa atacaccaat cgataaacat acgcatgtac ttttcttttt
    11941 tgaggatgga agccaacttc gctacaacga tgtacgaaaa tttggtcgta tgacaatcgt
    12001 cgaaaaagga gcaagtgcaa cttaccgagg aatcatgaaa ttgggacctg agcctttgcc
    12061 agatagcttc ttattagcag atttcgcaaa tggactgaaa aagtcccaca aagcaatcaa
    12121 gccattgctg ctagaccaac gtctagtgac tggtctaggt aatatttatg tagatgaagc
    12181 attatgggaa gcgaagatcc atccagaaca accggcgaac acactgcgcc ccaaagaggt
    12241 agaacaatta cgtctatcga tcattgatgt tttggatcgt gcaatagaag ccggaggtac
    12301 cacgattcgc agttatttga atgcattagg agaatcaggc ggatttcaag tagcactgca
    12361 tgtctatcag caaactggca aaccatgtat acgttgtgga acgccgatcg tgaaaacaaa
    12421 agtggcacaa agggggacgc actattgtcc gaattgtcaa aggctaaaaa tcgcaaagta
    12481 ggatttgttt taggtttgac gggtggaata gctaccggta aaagtacggc agccaaagtc
    12541 tttcagtctc atggatttcc tttgatcgat ggcgatgtga ttgccagaga aactgttgag
    12601 cctggaacgc ttgctctgag gaaaattgta tcagtgtttg gccaagaggt attgcagcct
    12661 gatgggcaac tagatcgagg gaaacttggg atgattgttt ttccatcaaa ggaaaaacgg
    12721 caaaaacttg atcagctatt agatccgttt atccgaaaag cgataaaaga tcaaatcgcc
    12781 tctctaagtt ccaatcatcc tttagtaatt gtagatatcc cattgctcta cgaaggtcat
    12841 tatgaccact atatggatgc agtagctgtc gtttatacta cgccagaaac tcagcttcag
    12901 cgtttgatga aacgtaatca actgacgcta gaacaagcgc agcagagaat tagtagtcaa
    12961 cttccaatcg aagaaaaaaa gcagcgtgcg gatattttgt tcgacaacaa tggaacaaaa
    13021 gaaatacttg tgggacaaat cgaaaattgg ctttttgcta atcgctttct ttgagtatct
    13081 gtgtcaattt tgctatcctg agtatataga aagtgaggga tagcgatggg atcattaaaa
    13141 aatcaaaagg ataaagtcgt aggtaacgca aaagaaaaaa tcggcgagat gctcaataaa
    13201 gaaaatctaa tcgatgaagg tcgtacgcaa tcagaaacag cagaagaaaa agaaaagcag
    13261 taccaagcaa gaatcgatga aatagaagac cagcaggcag aagaagaagc gaagcggcaa
    13321 gatttgactc aagaacgaaa aaatccgaca cctgatcgta gtaaaacacc gctcccagaa
    13381 agtgaccaca ttcccgatga gcaaaaaatc gaggaacagc gaatgaaaca ctatacagga
    13441 atcgaagaga agttataaaa tagtaaaaaa tcgagatgtg acttgaagca gatgagaagg
    13501 tgttcatctg cttcaagttt tttgtgctag atgactaaat cagcttttgt gtaagttatt
    13561 tctcagtaat caaggtgatc agtattggaa aattgaaatt tagtaaggac aggggacaca
    13621 attacgcatg aaagtagaaa aaattgttct tatatccgtg ttttttgggt aggacagtcg
    13681 cgtttgtgat ttgtttcgtg ttataataca actagttgta aagaaagaca catcctttat
    13741 ataaaatgcg atgcaagagg tgagacaaaa tgagatgtcc cagatgtcaa cataataatt
    13801 cacgagtaat cgacagccgt caagcagatg atggacgtgc gatccgtcgc cgtcgcgaat
    13861 gtgagaattg ttcgttccga ttcactacat ttgaacgaat tgaagctgct ccgttattag
    13921 taatcaagaa aaacggggaa cgcgaagagt tcaatcgcga taaaatttta agaggactca
    13981 tccgttcagc agaaaaaaga cctgtagcta tggaacaaat ggaacaaatc gtcaaccatg
    14041 tcgaaaaccg cgtacgcagt ctcggagaaa acgaagtatc gacgaatcta attggtgaat
    14101 atgtgatgga agatttagtt gatttagacg aaatcgctta tattcgtttt gcaagtgttt
    14161 atcgccagtt caaagatatg tctgttttct taaaagagtt gcaagatatc gtggataaag
    14221 caaaagaaaa taataaagag aataataaag aaaacaatta agaaacaaaa aggaggcatt
    14281 tccttggaaa atgcttggaa agagcttcaa ccaaaaaata tttaccaagg aagaaaagcg
    14341 gctccgctga gagaagacag caagaacgcc ttgctgtatc tttatcagcc actaatcggc
    14401 ggagaagcct tgagtatcta tttcaccctg ttatcagaaa tctctcaaga atctggcaaa
    14461 ggtcctgaag ggatgcatgc agatctgctt agtagtctag gctgcggtat cccgcaattt
    14521 tatgatgcaa gaaaaaagct agaaggaatc ggcttactgg atgtttattt taaagaagat
    14581 agtgatctgg gacctcgttt tatttatgag ctgttagaac cactcattcc taaagcattt
    14641 ttcaaagact ctgttctggc ttttcttctt ctggaaaaag ttggtgaacg acgattccag
    14701 aagcttaccc aattctttga acctaaaagg catacagcag agggatatca aaaaatcaca
    14761 aaaaaatttt tagatgttta tcgcttcaat gaagcagtgt acgctgctaa tcaagaaaac
    14821 atcgaatcgc tgaataaatc ttttgaagaa tctgaatcag tagcattact tgaagcagat
    14881 tcgacattcg attggcagtt tttgaatgat tggctggcaa aaaaacatat tgcaagtctt
    14941 gatgatccaa tcatcaaaca agtcgacatg tatcatcagc tttacggttt cgatgaattg
    15001 acacttggcg aactgatcag tcaatcttat gactttagtg aacaaaaagt atctgaaaaa
    15061 gaactgcaaa aagccatttt ggcaatgcag agacgtccgg tgaagcaaac aaaagaaaca
    15121 gttgcggttt ctgaaaacag taatgaaccc tcgtcaaacg aacatttgac aaacgcagcg
    15181 cttcagctga taaaagaagc acagagcatt ccaccgatga aatatctgga agcaatcaag
    15241 tcagaaaaag gcggatatgt ttctaaacaa gaaaactggt tactgcaaga tcttgtttct
    15301 caatcaggtc tttccagtag cgtgatcaat gttttgctga attatgtact agtgatcaag
    15361 aataatgcta gcttaaatgc cagttatgta aatacagtgg caaatgaatg ggcacaaaag
    15421 aaaatcgcca cagcagaaga agcgatccag cacattcggc aaataagtaa tcaagcaaaa
    15481 caatcaaaac aaaagaagca aacaaattat caaactggca agcgaaatgt tcgacgggaa
    15541 aagcttcctg attgggtcaa ccagccaaaa gatgaaaaac agatcagcag cgagaaaaaa
    15601 gcagagattg accgccgttt taaagaatac ctggcaaaaa aggagggtga tatctagtgg
    15661 aagacgtagg caaagaattg aagaggatca tcagcaaacg caattatcaa gaaaagtatg
    15721 ctgaaatgat cgctgaagtc ttaaatgatg cggatgttca agcttttcta agcgcacacc
    15781 aagaagaatt gacacaagcg gatattgaaa aaagttacgc taaattgtat gaattcgtgc
    15841 aagaaaagcg taaatatcaa aaaaacgatc caacgatgat cgctcccggc tatgagccga
    15901 agctgacgtt gaattttcat tatgtggatg tcacttatgt accaacggaa gcattgttag
    15961 cacggcaaag acaagaagaa atcagaagcc gagtaaaagc aatggatatg ccaaaagata
    16021 ttcaatcggc ttcttttgaa aactttgaac gtacagatgg acgaggatat gcgagcttag
    16081 aagccctaga ttttgtagag aaatatactg ctgatccaaa agggtatcat aaaggactgt
    16141 atctagtagg aagttttggt attggaaaaa catatttatt aggagcaaca gcgagagaat
    16201 tagcgattgc tggattcacc acgacgctag tccattttcc gacatttgcc gttgagatga
    16261 aacaggcaat cggaaaagat caagtggcag aaaagttaga tgcagtgaaa cgttcaccta
    16321 ttttgatgat cgatgacatt ggtgcagatg cgatgagtag ttggatacga gacgaagtat
    16381 tcggtgttat ccttcaatat cggatgcagg aacagttacc aaccttcttc tcatcgaatt
    16441 ttacaatgga tgaattggaa cagcatttgt ccgtcactca acgtggagat gaagagccgc
    16501 taaaagcgaa acggataatg gaacgcatac gttatttgac aaaagaaatc gaaatgactg
    16561 gtcgcaaccg acgcaatggt tgaacagttg acaagtccaa ctgacatttg acctagtagt
    16621 aaaagcaggt cagcgaatca ttatatggac agaaatgacc ggagacaatc accgcaacaa
    16681 gtaatgcaga aacttaaacg gaggattttt tatgagggct attttttcta gtatatctgt
    16741 agttggtcta ttttttcttt tagcaggctg cggtagcgca gatagcaaca caggttctgt
    16801 tgattcgatt gatgcgggtc aaacagtaaa aacaagcagt acgaaaacgg agagacaaag
    16861 catatttgtc ggaacgattg aaagtatcac tcaagtagaa gcagaagaag aaacgcttca
    16921 gttgaaactc gtcgatgtca tggccaaaga agatccagcg aatatgggaa cgtcattcag
    16981 caatgacgga gtgatcttaa atgctactgc tgaaaaaata agcgtggaca taaatgaatt
    17041 gaaaatcggt gacaaagtcc aatttacatt agttgagatg ccgatcatga cgatgtctat
    17101 cccaccgcaa gttcctggag attcgattat tgatgtttca ttgaacaaat aaccaataac
    17161 attttttcaa aaataagaaa atgttgtttt atagaacgaa aaggtatatt ttttaaggag
    17221 atatgggaat ttttttattc ctagtctcct tattttattt ggaaaatgct ataattatct
    17281 agaaggagtg aagctatgaa ccatttagat ttatctcagc gcttagccgc agtgggtgac
    17341 tttgtccctg aatccgctcg tttagcagac attggatcag atcacgctta cttacccgtt
    17401 gcattgatat taagaggaaa aatcgaatat gcagttgctg gtgaagtcgt tcaaggtcct
    17461 tatgaatcag cacgtaagca agtcaaaaaa gatggattag aagaccgtat caccgtacgc
    17521 cttgcaaatg gtctagatgc tatccagcca caagatggta ttacagctgt cacgattgcg
    17581 ggtatgggag gttcactgat ccgagatatc ctagaagctg gcaagttgaa tcaacgctta
    17641 agcggacaag aacgtttgat ccttcagcca aacatcggag agcgtacatt acgatcttgg
    17701 ctgcaagaaa atcagtataa aatccaatca gaaaaaatac ttgaagaaaa taaaaaaata
    17761 tatgaaatca ttgtagccga aaaagaacaa aaaccagtta cttacaatga aatggagctg
    17821 atgttcgggc catttctgct tgaagagaaa agtgagatct tcaaatcaaa atggacaaga
    17881 gagcttcaac aaagaaaagc tatccgtgaa cagctcaaac aagcagctaa tcaagaggca
    17941 cgtcaaaaac aaatcgagca ggaaatccaa atgattgagg aggttttaaa gccatgacaa
    18001 tcagcggacg cactttcatc caaaagtttg aaagctattg tcctcagtgg ctagctgaag
    18061 aaggagaccc agtcggactg catatcggaa cattggataa gccaatccaa cgagtaatga
    18121 tgacattaga cgttcgtcca gaagtggtcg aagaagcaat caagaaaaaa atcgatttgc
    18181 tgattgctaa acatcctcca atctttcgtc ctgtaaaacg gctggttact gatcagccac
    18241 aagaaaaaat gtatgcagat ttgttgaaac atgatattgc cgtctatgca gcacacacga
    18301 acatggatat tatttgggat ggactgaatg actggttttg tgaacttctc ggtattgaag
    18361 tggagagtta tttagtaaag actcatgaga ttcattataa aaaactggcc gtttatgtac
    18421 ctgtggatca tgcacagaaa atgcgtgaag tattagctgc agctggtgct ggtacacaag
    18481 gtgattatac cggtacaagt tttacctcga ttggacacgg tcgatttact ccggaagctg
    18541 gtgcacaacc agcgattggg aaagtaggga agacagaaca agttcaagag gcaaaagttg
    18601 aggttatttt gccggaaact atcgaaaaac aagtgattca agccatgcgg tcagctcatc
    18661 cttatgagga acctgcttat gatcttttcg ctatagatga accagtcgaa atgtttgggt
    18721 taggacgagt aggtgaattg ccgcaagaaa tttctataga ggcatttgta gaacaagtaa
    18781 aagaagcgtt ccaactagat ggactgagaa tagtccagcc aaaaaatgca aaatcctctg
    18841 tgaagcgcat tgcgatttgc ggtggaagcg gtgaaaaatt ttatccgcaa gcaatcgccc
    18901 aaagagcaga tgtctatatc acgggagata tctattatca tacggctcat gatatgcaaa
    18961 gcgctgggtt gattgcaatt gatcccggtc attatattga atcgttatgc aagcaacgat
    19021 ttatcgagaa atttgaatct tggaaacaag aagaaaattg ggatattaac tttttcgttt
    19081 ctgaaacaaa tacaaaccca tttcaattta attaaaagga gagaatacta tgtacgaaaa
    19141 tcttttgcca cgttttttac gatatgtcaa aacagaaaca cgctccgatg caacaagcaa
    19201 aacgactcca tcgactcaga cacaagttgc ttttgcgcaa gaattgaaaa aagaattaga
    19261 agagttaggc ttagctgatg ttttctataa tgaagataac ggattcgtta tgggaacatt
    19321 accaagcaat gttgatcatg aagtgcgttc cattggattt atttcccaca tggatacagc
    19381 agattttaat gcagtaggag tcaatccaca aatcattgaa aactatgatg gcgagtctac
    19441 gatcgtacta gatgcggaag aacgctatac attgaataca aaagattttc caaatttgaa
    19501 aaattatgaa ggccacacat tgatcacaac agatggcagt acattactgg gagcagatga
    19561 caaatcaggg attgcggaaa tcatgactgc aatggagatc ttgatcaata atccttctat
    19621 ccctcacggt accatcaaag tggcttttgg tcctgatgaa gaaatcggtg tcggagcgga
    19681 taaattcgat gttgagcaat tcgatgtaga ttttgcttat acagtcgatg gtggtccttt
    19741 aggtgagttg cagtatgaaa cgtttagtgc tgctcaagca aatattacga tccaagggaa
    19801 aaatgtacat ccagggacgg caaaagatac aatgatcaat gctctacagt tagcaatcga
    19861 ttttcataat cagcttccag ccgatgaagt tccagaaaaa acggaaggat acgaaggttt
    19921 cttccatttg atggcattgg atgggaatcc tgaagaagct tctatgagtt atatcattcg
    19981 cgatcatgat cgtgaaaaat tcgaagcacg caaagcacaa atcacacata tccaagaaga
    20041 gttgaatcag cgatttgatc aagaacgaat caaagtagat atgtatgatc aatattacaa
    20101 catgaaagaa atcattgaaa aagatatgag catcgtggaa ttagcgaaac aagcaatgat
    20161 cgagcttggt atctctccag tgatcgaacc agttcgtgga ggaacagatg gttcaaaaat
    20221 ctcttacatg ggtattccga cgccaaatct atttgccgga ggagaaaata tgcacggacg
    20281 attcgaattt gtttctttac aagtaatgga aaaagcaaca gacgtgattg taaaaattgc
    20341 agaattgaac acaaagagtt aaaatcgaaa aagaacagct tatgacaagg cgttcgtccc
    20401 aatgatggaa tgtcatctgt ctaaggctaa agggcaggac aatggaattg gttgtcccgc
    20461 cctctttttt gaagagtaaa taggaggtaa agaatggaaa agctgctagt tttttataac
    20521 aaaagttcag ggaaagatga gggtgagaaa ttagcacgct ggtttcaaga ttatgtaaaa
    20581 gaaaagcagc cagaattata tgtagaacta gctgaaactg gcccatcgat tgatgatgcg
    20641 gaattagtca agaaagcaga agccatagaa gctgatactt tagtaattat aggtggagac
    20701 ggcacgattc atcatatcgt ccaagcgttc caaaaaacat tatctcaata ccatgtcgga
    20761 ttacttccag gtggaactgt caacaacctt gcacgtgttc ttgagattcc cctcaaaaaa
    20821 gaagaagctg ctgacgtgat cctggaaggc aatgtacgga aaatagacta tggtcaagtc
    20881 aatgatgaag tcattatctc tacactgaca atcggaatct tagcagatac agcagtttgg
    20941 atcagtcaag aagaaaaaca gcgttacggc tcgtggatct ttatcaagaa gttttttaag
    21001 ttattgctga agaagaaaaa atatcatttg gatttagaaa cagacgagga gcattggaaa
    21061 ggaaaatccc aactgttgac agtcacgatg tctaactccg tgggcggttt tacaaatttt
    21121 gacgactcag cgaccctaga tgatggaaaa tttcatgtaa cgatcgtacc ttccttagat
    21181 attttccgat ttatttttta tttgcctaga atcatgagag gcaaattcta tacgatcccc
    21241 ggcattactt atttcacagc caaacgcatg aaaatccaag cgcaggaaaa atctgtgggc
    21301 actcgaacgg atggagacac gacagatgat cttccagttg aattatctgt tgtatcaaaa
    21361 ggattaacag tttattcacc aaagaaagaa gaaaaagctt agaaatagta gttaacagaa
    21421 agttggaaga agagtaatgg atgtattgtt acacaatcct ttgtggtttt accttttcat
    21481 tgtgaatttt tacttatttt gtctgatggg gtatgataaa catcaggcta gaactagcgg
    21541 ctggcgtgtt cctgagaata atttgatatt tgtcagcctg ttaggcggtg gtttgggagg
    21601 attgatctct cgaaaagttt tccatcataa aactcggaaa aagaagttta ctataggatt
    21661 cgctgcaggt gtacttgttg atttgattct catttatttt ttccattaag gagcaggaga
    21721 tgtcgtctaa aggaacgaaa actaaaatca ttctgaatct gcttttgctg attgtgattt
    21781 ttgccattat ttattattta atcaatcaat catttgcaga tatctttgcc gaattgctgt
    21841 ctaccagtgt tgttgttttg gcagcggctg ttatattagg gacagtttac caaatcgctg
    21901 aagggcgctc aatcaaagaa attgctgaac ctttcgcgcc gaattttaca acgaaagatg
    21961 ggttcttgac ctctagctat attgcgtttt accgaatcgt ttcgtttggt acaggaacgc
    22021 tgatctcgga gatttatttt tataacaaaa aaggaatgaa gctatcccag ggagcagggg
    22081 tgacagcact ccatatgatt atgtacaaac tggcagtgat cacttatgca ttagctggct
    22141 tggtcatcca attctctctt ttttattcta atggtccatc aatgatctgg tttatcatcg
    22201 ctggtatcct tttgacgatc gtgattgttg cctttttatt ggcgatgtcc gtcagcttga
    22261 atgttcaaat attttttgtc agcttatcga ataagttatt taaaagtgag cgtttgcgga
    22321 aatgggtgga tacatgcaat cagcagatct actctttaag ggaaacggtc caaaccatta
    22381 tccaagacag gactgcgcta ttgcggattt atctatggaa tatgttaaaa cttgtatttt
    22441 ggtatgtact tccttatttg attctgattg aaaaccatcc taaaatagat tttctactga
    22501 ccatttcgtt tatcagcttt gcagtagtgc tttcaggggt tattcctacg cctgctggta
    22561 ttggttcctt tgaatttgtc tatttgttat tattcagacc agttgttgga acagttgacg
    22621 cagtttcttc gcttttactg tatcgtttca gttcctttat cttgccattt ctctatggat
    22681 ttgtgtatgt gattgctgaa cggcgaagag tgatcaaaga agaaataata gaagtaaaaa
    22741 aagagaataa agaaaatcaa gggtaggtct tttataagat ctaccctttt tatcaaatca
    22801 aagaaaaacg ttatggataa gataatttta cgtttgtttg gctctttttt tatatacata
    22861 caatcaattt tgttttttta agatttatat aagtcgagaa aaaaagtcaa aaaactatgt
    22921 gtatattttg accaaaattg accaaagcga tataatagtt tttgtaaaga tcaaagaaat
    22981 aagtgatctt acctttaatt aggagggtat acctgtatga atattgagaa aatgactacg
    23041 acgcttcaag aagcgattgc tgaagctcaa cagattgcgg tcactcgaaa acatcaagat
    23101 atcgacattg cccatgtatg gaaaatcttt ttacaatcta atcattttgg tcgaaatttc
    23161 tatacggatg ccggattgga tgtcgaatct tttgaacatg aaattgatcg tctactggat
    23221 gagtatccag ttgtttctgg tggaaacgtc caatatggac aaaacctcag ccagaatttc
    23281 tttcgattat tgaatgaagc agaccaaata cgtgaaagct tcggcgacga gtttctttca
    23341 acggaagtcg ttattttagc gttgatgaaa ttaaaaaatt atccgttaac tgtttatttg
    23401 aataaaaacg gattatctga aaaagaattg cgtaaaaaca tcgaagagat gagaggagga
    23461 gaaagagtga cctcacaaaa ccaagaagaa caatacaaag cattagaaaa atacggcgtt
    23521 gatttagtac agcaagtcaa aagcggaaaa atggatccaa tcatcggtcg tgatgaagaa
    23581 atccgtgatg tcatccgtat tctttcacga aaaacaaaaa ataatcctgt tctgatagga
    23641 gaacccggtg tagggaaaac ggcaatcgtt gaagggcttg ctcaacgtat cgtacgcaaa
    23701 gatgtgcctg aaaatttaaa agataaaacg attttttcat tagatatggg tgcattgatc
    23761 gctggagcaa aattccgtgg tgaatttgaa gaaagactaa aagcagtctt gaaagaagtc
    23821 aaaaaaagtg atggacgtat cctcttgttc atcgatgaaa tccacaatat cgtaggggca
    23881 ggaaaaacag aaggaagtat ggatgccgga aatctgttga aaccaatgct tgctcgcggt
    23941 gaattacatt tgatcggtgc cacaacttta gatgagtacc gtcaatatat ggaaaaagac
    24001 aaagcgttgg aacgtcgctt tcaaaaggta ttagtcaaag aaccaacagt ggaagatacg
    24061 atcagtattc tgcgtggatt aaaagaacgt tttgagatcc accatggtgt taacatccat
    24121 gacaacgcat tagtagcagc agctacttta tctgaccgtt atattactga tcggttctta
    24181 ccggacaaag caatcgattt gatcgatgaa gccagtgcaa cgattcgggt agaaatgaac
    24241 tctatgccaa cggaattaga tcaagttact agacgtttga tgcagttgga aatcgaagaa
    24301 gctgcactga aaaaagaatc agatgatgca agtaaaaaac gcttgaaaaa tttgcaagaa
    24361 gaattagctg aacttcgtga agaagcaaat gcgatgaaga tgcagtggga aacagaaaaa
    24421 gaagaagtca attctgtttc agcaaaacgt gctgaaatcg ataaagcaaa acacgaatta
    24481 gaagatgcag aaaataacta tgatttagaa cgcgctgctg tattgcgtca tggtacgata
    24541 cctcaattag aaaaagaatt gaaggaatta gaagctaaag caaaagacag cgagattaag
    24601 atggttcaag agtccgttac cgaaaatgag attgctcaag tcgttggcag attaacgggt
    24661 atccccgtaa cgaaacttgt agaaggtgaa cgagaaaaac taattaaatt gaatgaaaca
    24721 cttcataaac gagtgattgg tcaagatgaa gcagttgatg cggtcagtga cgcggtaatt
    24781 cgttcacggg ctggattgca agacccaaat cgtcctctag gttctttcct tttcctagga
    24841 ccaactggtg tcggaaaaac cgaattagcg aaagcgttag ctgagaactt gtttgactca
    24901 gaagatcata tggtacggat cgatatgagt gaatatatgg aaaaacatgc tgtgtctcgt
    24961 ctagtcggag ctcctccagg ctatgtaggt tacgaagaag gtggtcaatt aacggaagct
    25021 gtcagacgaa atccttatac aatcgtcttg ttggatgaaa tcgaaaaagc gcatcccgat
    25081 gtcttcaata tcttgttaca agtcctagat gacggacgct tgactgattc aaaagggcga
    25141 gtagtagatt tcaaaaatac ggttctgatc atgaccagca atatcggttc acagttactg
    25201 ctggaaggcg tgactgctga tggaacgatt ccagaagcag tggctgaaca agtcaacacg
    25261 ctattacgtg gaaacttcaa accagaattc ttgaaccgaa tcgacgacac gattttattt
    25321 acaccattga gcctagacaa cgtgaaagga atcgttgaca aaatggtggc gcaattggca
    25381 caacgtctgg aacatcaaga aatcctgctg acaatcagtg atgaagccaa aacgtggatt
    25441 gctgaaaatg cttatgaacc agcatatggt gcaagaccat tgaaacgatt tatcactaag
    25501 gaagtagaaa caccactagc taaagaaatc gttgcaggac atgttatgcc taaatcaaaa
    25561 gtaacgatta ctttacttga tggacaactt catttcaaaa cagaagagct agaagaaatc
    25621 gtctaatctt ccattgagac tataaaagaa aaaaggggtc tgacacaact agtgtcagac
    25681 ctcctttttt caaataaaca gtgttccaga agtagtttct tcgaaaaata agccgaaatt
    25741 tcttgaagct gcccgcttct gtcacaacct cttttattag gtatttttca ctttttctaa
    25801 tttataactt tcaaagtaac gctcatcttt tttactttga gaccatgcaa acaatcccat
    25861 taaggcagca cctatcgtat ttgtcagcaa gtcgcccatc gtatccatca atgctgctcg
    25921 tccgacaaac agtgtgccat cagaagcagc aaaacgttga agattcatgc ctaagaactg
    25981 gtcgcataag aattcccaga actcccaaaa cacgccgcaa agtccagcaa acgcaaagcc
    26041 gaataagagg aacaaccaag gactggtttt tgatatctca gcatctttca tcaagtaacc
    26101 aatcaatcca tagccaagag ctgtcaggac cattggactc accgcatgta agattttgtc
    26161 ccaaaaagag atgatactga tcaaatgcat ccctgtgcct aaaaagacag agatgaacaa
    26221 gaaaaaccag taaaacaaaa cgattgctgc tggtatttta agtttgaaaa ctttcaaaat
    26281 gacttgtggc atgaaaatca atgcaatccc taataaagat tccacgataa atgtgattcc
    26341 ttgagaagtc gaatattttt gtgtgataaa ttcataaaaa ttatagcaga caacgaatac
    26401 accaaaagca agtaaagcta tttgcacctt tttgatttct ttaatcactg aaagtccctc
    26461 catctaaaaa tctttttact tctgaaagca actcaatttc tgaagaaacc acttttccgt
    26521 tcaatttgat caaacctatt gtatataagt tcaggtagtg aaattgattt tcagctgttt
    26581 cttgtagtgc agcgattttt ttcgggtggg ttccgccttg ctgtcgagta tcagtatata
    26641 agccgatcac tgggatgcct ttcgcataag ccacaccgat ttccgatgct accccggcat
    26701 cgatcgtcag cccatctagt aaagcaatca ttaaatcact agccaacact ttttctgtgt
    26761 cagcaagagc aatcattcga ctgtctgcat aagcagtttt gtcattgatt gcttcatttt
    26821 cttgaggaag atagatcgaa agctcagaag agagctctct gatttcttta actaactgtt
    26881 ggttatataa caaatcactt ttagcaaaca ttggtgcggc aaaataaatt ttcatctaaa
    26941 catcatcctt tttatcaaaa ataatcgcta aagtaagctt ccatgtttgg aatgatacgc
    27001 tctagtgact tcagtgtttc ttcatctgtt tctaaccgtt cgattcttgc caaataagaa
    27061 gcacggcgat aattcatcat caagcaagtc aatgtttgga tatccagtcg aacggatttt
    27121 cctataggtt catttaagac acggacttgt ccctgttcat cccatgttaa agcgaagaca
    27181 ccattattcc aaggagcgac aggatcttca atgatgaaat gaaaagcatc agctgttcca
    27241 acaaacggaa accgttgaag gaattctttt acatcaacga tccgagccat aaaatatggt
    27301 tcgatctgct ctttgatctg actatcttca atcaaaaatg ctaaaggctc atttttataa
    27361 atatctccat gtacccagta gatcatggaa aaatgtgcgg aaataaagtt ccataagcca
    27421 tttcgagctt cttgatcaag atagaacatt tcttttacgt gaaatatttc ttcagctacc
    27481 cagtagaaca gaacacctct tggttcatgg ttgctatcgt agtagacagc ggctgtgcgc
    27541 tcatcttcat tttcgaaacg ccaatactct tcccaatgaa aatcactgcg gaataaagca
    27601 ccatggtttt gttgggcaaa tttgtcataa acggaaaata cgtctggatg atcaactggt
    27661 aatcgctcaa ccataccact tactgggatt tgtttaggta gctgtgtatc tctgatttta
    27721 aaggaaagtt tatcagacat gatttcccat cctttacgcc gatagtaggg gatactgtaa
    27781 ggatacaaat aagagatcca ttgcttattc ttgcgcatat tatccaatgc aacgataatt
    27841 agatcttgca tcaatccatg gttagcatat tctggataag ttccaactcc agtcacacca
    27901 cccattttat aacgtgcacc gtgaatattg acttcacaag gatagatagc gatttgagag
    27961 atcagtttat tttcgtggaa ccatccgaac actttcgata cttccaaaat cggttttttg
    28021 gaacggataa aagctcgttt attctcaaac ccgctttcct cgatgtctgc ttcagtcact
    28081 tggaacacat aggaaagcaa ttcattgaat tgatcgatat gttcttgagt gaccggtttt
    28141 aattcaagat tttctctaaa atctttttga tccatttttt catctccatt tattagcttg
    28201 ataacagtat agcaaaattc tacaaaaaaa acttctatag ctgactaatt aaaaactctt
    28261 taaattactg cttttcgttg gtataatgga aagtgctgat tatatgaaaa gaggagacgc
    28321 tatggatata aagaaaatga aagaacgcca agagcagatt cgtaattttt cgatcatcgc
    28381 tcatatcgac catgggaaat ctacattggc cgatcgtatt ttagaaatga cgcacactgt
    28441 gacgtctcgc gaaatgcaag atcagctgtt agactcgatg gatttggaac gtgaacgtgg
    28501 aatcacgatt aaattaaatg ctgtagaact caattacaca gcgaaaaatg gagaaacata
    28561 tatctttcac ttgattgaca ccccagggca cgtcgacttc acctatgaag tctctcgaag
    28621 ccttgctgcc tgtgagggtg ccgttttagt ggtcgatgca gcacaaggaa tcgaagcaca
    28681 aacattggcc aatgtttatt tagcgttaga caatgatttg gagatcctgc cagtcatcaa
    28741 taaaatcgac ctacccgcag cagatcccga acgtgtccgt caagaaatcg aagacgtaat
    28801 cggaatcgat gctagtgaag ctgtattagc cagtgccaaa tcagggattg ggattgaaga
    28861 tattctcgag cagatcgtgg aatatgttcc tgcaccaagt ggagacttag atgcaccgct
    28921 aaaagctttg atctttgact ctatttatga tagttaccgc ggtgttgttc taaatgtccg
    28981 gatcacggac ggtatggtca aacccggaga caaaatcaaa ctgatgagta atggcaaaac
    29041 atttgatgtt acagaggtcg gggtcttctc gccaaaagca gttgctagag actttttgat
    29101 ggtcggtgat gtcggttata tcacagcaag tatcaaaact gtccaagata cacgagtagg
    29161 ggatacagta acgttagcag acaatcctgc cgctgaagct ttaccaggtt accgaaaaat
    29221 gaatccgatg gtttattgtg gtctttatcc aattgatact tctcgttaca acgatttgcg
    29281 ggaagcttta gaaaaactgc aattgaatga tgctgcttta caattcgaac cagaaacctc
    29341 tcaagcatta ggttttgggt tccgctgtgg attcctcgga cttcttcata tggatgtcgt
    29401 ccaagaacgc ttggaacggg aattcaatct agaattgatc acgactgcac catccgttat
    29461 ttaccatgtt aataaaacgg atggtacgac tgctacagta gataacccgg cagattttcc
    29521 tgaacctgta acgattcagg atgtagaaga accattcgtc aaagcacaga tcatggtccc
    29581 aaatgatttt gtcggtgcag taatggaact ttctcaacga aaacggggag aattcattac
    29641 gatggattat ttagatgatt accgagtaaa tgtcgtctat aatattccgc tttctgaaat
    29701 tgtctttgac tttttcgaca aattgaaatc aagcacgaaa ggctatgcct cattggatta
    29761 tgaaatgtct ggttatcaaa aaagcaagtt agtgaagatg gacatcttgc tgaatggaga
    29821 aaaagtcgat gcattaagct ttatcgttca ccgagacttt gcctatgaac gtggaaaagc
    29881 aatcgttgaa aaactgaaaa aactaatccc acgccaacaa tttgaggtgc caatccaagc
    29941 agctattgga caaaaaatcg ttgcccgttc agacatcaaa gccttgcgta aaaacgtctt
    30001 ggctaaatgt tatggtggag atgtttctcg taaacgtaaa ctcttagaga aacaaaaaga
    30061 agggaagaag cggatgaaac aaatcggctc cgtcgaagtt ccgcaagaag ccttcatggc
    30121 cgttctgaaa atggatgagc aagatagtgt gaaataactt ataatcaatc gaaaaaccta
    30181 ttaaataaac ctttttgagt agatgcaaca ctgaggatta tctgtataaa agattttaaa
    30241 ctgtcatttg gttatcacgg cgatactaaa attaacaaaa ttggaatatt tttcttgaag
    30301 atttttagct gtcagtatat gatgaaagca tctcatagga ggtgcttttt tcatggttga
    30361 taattcaagt ggaagggttc ttaaatctct aagaaaagag aaaaaactat ctcaaaaaaa
    30421 gttagctgat ttagcaggta tttcacaaag tactttagtt aaatatgaaa aagggtcaag
    30481 aaaaatccct aaagacgtag ataatactct aagcaagatt ctgaatatag aaactctaat
    30541 aaaagatgag gaagataaga ttgagattct catcggtaaa ctaattgcat acagagatat
    30601 gaataagtta cttaacaaag agttagctga taatatagga attagtgaag tattactcag
    30661 ttatgtgtta aatagaaaga gaaatccgtc aaaagaaatg caaaaaaaaa tcgatatttt
    30721 tctattaagt aatgaaaaag aaattttgaa ggagattaat cgtgatagtg agatatttag
    30781 tttatcaaaa gacgataaaa ttgttatggg aaaaagaata cgagaagtcc gaaagaaccg
    30841 ggaagagacg cttgaaaaat ttggtaaaaa ctttaccatc tatacaggca aaaatgttat
    30901 aagtagatgg gaaaaaggta ttaatattcc agatattgaa aaactaatga atattgccta
    30961 tcttggtaag gtcactgttc cttaccttat gtacggagaa gattataaga atatacttcc
    31021 aaaagatgaa agagttagcg attttaaaaa gataaattct tttagtatgg gattaaggat
    31081 gaggaaaatt aggaaagatt attatctaga aagggaggag tttggaaagc ttttttctcc
    31141 ttcaatttca aaatggtcca tagataggta tgagaatggt agagatatac ccaatactaa
    31201 tcgaattatc caatatgctt atataggaaa tctttcttta gaatttttga tttacgggat
    31261 ataaaaatag tttacgtcga tacttattaa
//
LOCUS       DAZAOD010000017        31283 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000017 DAZAOD010000000
VERSION     DAZAOD010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.018"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(313..2205)
                     /locus_tag="ACHDPO_000918"
     CDS             complement(313..2205)
                     /locus_tag="ACHDPO_000918"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368563.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="ACHDPO_000919"
     CDS             complement(2202..3929)
                     /locus_tag="ACHDPO_000919"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368564.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="ACHDPO_000920"
     CDS             complement(3945..4595)
                     /locus_tag="ACHDPO_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFN3368565.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="ACHDPO_000921"
     CDS             4799..5095
                     /locus_tag="ACHDPO_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFN3368566.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="ACHDPO_000922"
     CDS             5287..5907
                     /locus_tag="ACHDPO_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFN3368567.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="ACHDPO_000923"
     CDS             complement(5999..7165)
                     /locus_tag="ACHDPO_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFN3368568.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="ACHDPO_000924"
     CDS             complement(7177..7530)
                     /locus_tag="ACHDPO_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFN3368569.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="ACHDPO_000925"
     CDS             7658..8680
                     /locus_tag="ACHDPO_000925"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFN3368570.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8699..8860
                     /locus_tag="ACHDPO_000926"
     CDS             8699..8860
                     /locus_tag="ACHDPO_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368571.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9119..9553)
                     /locus_tag="ACHDPO_000927"
     CDS             complement(9119..9553)
                     /locus_tag="ACHDPO_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368572.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="ACHDPO_000928"
     CDS             complement(9663..11522)
                     /locus_tag="ACHDPO_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFN3368573.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            11523..11663
                     /locus_tag="ACHDPO_000929"
     CDS             11523..11663
                     /locus_tag="ACHDPO_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFN3368574.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(11640..12800)
                     /locus_tag="ACHDPO_000930"
     CDS             complement(11640..12800)
                     /locus_tag="ACHDPO_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFN3368575.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="ACHDPO_000931"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="ACHDPO_000931"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFN3368576.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="ACHDPO_000932"
     CDS             complement(14547..15245)
                     /locus_tag="ACHDPO_000932"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFN3368577.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="ACHDPO_000933"
     CDS             complement(15202..16863)
                     /locus_tag="ACHDPO_000933"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFN3368578.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="ACHDPO_000934"
     CDS             17081..18481
                     /locus_tag="ACHDPO_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFN3368579.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="ACHDPO_000935"
     CDS             complement(18733..19812)
                     /locus_tag="ACHDPO_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3368580.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="ACHDPO_000936"
     CDS             complement(19898..20857)
                     /locus_tag="ACHDPO_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFN3368581.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSKKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22380)
                     /locus_tag="ACHDPO_000937"
     CDS             complement(20869..22380)
                     /locus_tag="ACHDPO_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFN3368582.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22402..22965)
                     /locus_tag="ACHDPO_000938"
     CDS             complement(22402..22965)
                     /locus_tag="ACHDPO_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFN3368583.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22971..23834)
                     /locus_tag="ACHDPO_000939"
     CDS             complement(22971..23834)
                     /locus_tag="ACHDPO_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3368584.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23848..24744)
                     /locus_tag="ACHDPO_000940"
     CDS             complement(23848..24744)
                     /locus_tag="ACHDPO_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3368585.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24919..26208)
                     /locus_tag="ACHDPO_000941"
     CDS             complement(24919..26208)
                     /locus_tag="ACHDPO_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3368586.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26180..27697)
                     /locus_tag="ACHDPO_000942"
     CDS             complement(26180..27697)
                     /locus_tag="ACHDPO_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFN3368587.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27895..28785
                     /locus_tag="ACHDPO_000943"
     CDS             27895..28785
                     /locus_tag="ACHDPO_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFN3368588.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28858..29682)
                     /gene="nadE"
                     /locus_tag="ACHDPO_000944"
     CDS             complement(28858..29682)
                     /gene="nadE"
                     /locus_tag="ACHDPO_000944"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFN3368589.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29694..31166)
                     /locus_tag="ACHDPO_000945"
     CDS             complement(29694..31166)
                     /locus_tag="ACHDPO_000945"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFN3368590.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
BASE COUNT         9119 a         6577 c         5436 g        10151 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 tttttttaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    21901 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    21961 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    22021 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    22081 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    22141 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    22201 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    22261 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    22321 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    22381 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    22441 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    22501 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    22561 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    22621 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    22681 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    22741 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    22801 tcctgatccc tcacctttcc attgcgccat tacataaaaa acagcacatg tagcaggcac
    22861 gatagtaata acaggcaaac acacgattac ccagagaata cctaataaga tgtaatcaga
    22921 aaccacaatc aactgtccat aaagtttagt ctcaactatt ttcatcttcc tcactctttc
    22981 attccagaca tagctgttcc ttgaacaaaa tatttctgtg caaaaatata aaccactagt
    23041 aatggcagca ttgaaataac cgttccagcc attacaggtc cataaaaaga aatgttctgc
    23101 cctgtaaata aagctaaccc tgctggtaaa gttctcattt ttgaactact tgtcaatatc
    23161 aatggataaa gcaagtcatt ccaactattc atcagcgtga aaatccctaa tgataaaaga
    23221 gtaggtttgc tcaatggcaa catgattttc aaaaaaatat taaactcact taatccatca
    23281 atgcgtgctg cctcttccaa agaatctggt aaagtaataa aaaaggaacg catcatgaag
    23341 ataccaaatg cagttgtcat acgaggaatg atcaaacctg cataagtatc aagcatgcca
    23401 agcaaattga cttcaataaa tagaggaatc atgaagactt ggaatgggat catcattgtc
    23461 agcaaaacga aatagaacaa aactgatttt cctttgaaac gcatacgagc aaatgcatac
    23521 cccgcaagag aatcaaagaa tacagaagtg atcactgtcc ctccagcaaa aatcactgta
    23581 tttttgatgt aatctaataa agggatcgtt gtccaaacct taatatagtt atctagggta
    23641 tagctatctg caaatattct aggcggaaat gagataatgt ctttttcgtg tttaaaagaa
    23701 gaaataatca gccacaaaaa aggaaacgca ataaccaaca atataactag catactaatc
    23761 gttcgaatga tttttttacc actaactgct tttcgactat tcacagtaac tgtaatcgag
    23821 ctttctggtg ccatacaggt ttccctccta tttcatttgt ttttctttcc gtgacatgta
    23881 cacattagtg gagatagcta tagttgcaac aatgataaac aaaaccgaag acagtgctga
    23941 tgcatagccc aattcataag gtgctgtaaa tcctcgactg taaatatatt gaacagctgt
    24001 ttctgtctta aattgtgggc caccagcggt tgcaacatat acttggtcaa acacttgcat
    24061 cgaaccaatc agattcgtta aaatacaaaa acctaaggag ggaacgatct gaggtagcgt
    24121 aatgttaaaa aactgctgtc gatttgttgc accatccatt tgagcagatt catacaaaga
    24181 gggagagatt ccctgaatag cagtcaagag aatcgtcata gtaacaccaa aattcttcca
    24241 aacagtcatg atggctaccg tcggcatagc aagggttgga tcgcgaaaaa attgagggat
    24301 cggcaagccg acttgtgaaa acaagtaagg aatcgcccct acattcggat caagcaacat
    24361 agaaaaaata atcgcaattg acgtcaatga acaaataact ggaatgtaaa atgtcgaacg
    24421 acaaaaacga ttgaatctgg tatttttaga taatgctact gctgctaata aaccaacgat
    24481 aatttgtgtt ggcgtttcga gtacggtgaa atataaagaa tgaatcaacg aattaactgc
    24541 tcgttcatca ctaaatatac gtgtgaaatt ttcaaaactt acaaaatttc ttgatgtaaa
    24601 gaaaatattc aaatctgtaa aactaatagc aaatgttcct aaaagcggta tgacagtaaa
    24661 taataataaa actaaaaaag atggagttaa aaacaaatac gcagcacgat caggacgatt
    24721 ccaatatttg gtgaatccgt tcatatagtc cacctcatct ttcattttga taaaatatac
    24781 aatcttggtt taaacgaatc tgaataagat atccgaacaa tcgctgtgat ttttgcaata
    24841 acacctatct gcaaatacta ggtcgatcat tcagatatct gtatcttgcc aacagtctat
    24901 cctgtataaa gttctgtact atttttgcag taattgattg atggcatcat ctgcatcgtt
    24961 catgagtgtc tcaggatctt ctcctgctaa taatttttca atcagtggat tgatgatatc
    25021 gttattgatc gcagagattt gggtaaaacc tggtaaatat ggctctgcat agtccatttg
    25081 tttcgataat tcagatacaa taggatcatt ttttacttct tcatcttttg ctactgaatc
    25141 caagtaggca ggaaaaccat tttcgatact ccatttttta ccaatttcag ttgtattcca
    25201 atatttcaaa aactcataga cagcttcttt tttattatta tctgtacttg ccggaatggc
    25261 atatcctacg ccatctaaaa tagctgtttt tttgtctgaa tcactccctt gtggtaaggt
    25321 agtcacatta taatcaatct cgtttgcttt caatccgtta tttaaccatg gcccattgat
    25381 ttcaatggct agttgaccag cattcattaa attgtccatt tcggcgccag aaatcgattc
    25441 tggaccagtc ttgtctacat ggatcatttt ttggatcgct tttaacgttt taaggttctc
    25501 aggagacgca aattcagact tagtataatc atcgttcact aatttaccgc catttgctaa
    25561 catccagtta tataacggtg cagttccatc cttattgaag acaaaacctg atacattttt
    25621 actactatca gttaattttg gtgccatttc tgtcaattct tcccaagtag taggtggttg
    25681 ttcagtatct aatccagctt gtttaaacaa atcattattc caatacatat acatgccttg
    25741 tacctgcatg gggacaaaat actgtttacc ttctacttca cctaattcaa tagccgtttc
    25801 tttaaaatca gatttatcta ctccatcata ttcccagaaa tcgtctaatg gttgtaccgc
    25861 tccgttttct acatactgtg caaaatctgg ataatttaat gcaataaagt caggtgcttt
    25921 tttagaagaa atcgctgtag gaagtttttc attcaaattg gcccaagtca tgatatccat
    25981 ttcaattttg atgtttttat catttgtttt attaaattca ttaacgattt cttgcaatat
    26041 ttcaccatca gatgcagtaa acccattcca aaaagtcaaa gtcacttctt tatcagaatc
    26101 agattctgct gaacttccgc caccgcaagc tcctaaaata cctgttgcag ctaccaacaa
    26161 agagccaatt aaccattttt tacctttcat tttttgttcc tccttcatct gataaacgac
    26221 atctgaccac attccaagat agcggtttca ataaacaatt gattttccca tcttcagctt
    26281 ttacatttgt tgaatgactt ggttttactt gttcactttt aggaagatta gttgcttttg
    26341 tatcaaatcc actcatttca gaaaaatcaa tcactccctc taatgataat tcagacaagt
    26401 gaacagttag attcatttct tcttctccac ggttaactgc aaatatgaca agttctttgt
    26461 catttattac ggctatactt tctaaatacg gcacttcttc aaaatcttcc gtcgcatagt
    26521 ttgctgaacg aatttgtggg cttaacacct ctccttgtcc atacacagca gcttgcataa
    26581 atggataata gatcgtctgt ctccaagctt ctccgtttgt ttctgtcctg attggtgcaa
    26641 taacatttac caattgagca agacaagcaa tctttactct atctgcatgt ttcaataaag
    26701 tgattaatag acagcctaat agtaatgcat cttcaaaatt atagttatct tctagtaaag
    26761 gaggagcaat ctgccaaggc gctgcttgct catcttgttc cgctgaatga taccaaatat
    26821 tccattcatc aaaggacagg ttgatctgct tcttactatg tttcttcgcc ttgactgtat
    26881 cgcacatcgc tgtcacttca gaaatgaacc gatccatgtc taaggaacgt gcaagataat
    26941 gagaaagatc atttttttgg ttgccataat attgatgcag agacaaataa tctatttgat
    27001 cgtacgcttg atcaagaact gttaactccc aatcaccaaa tgtaggcatt tgccgattcg
    27061 aacttccgca taaaaccacc tcaattgaat catctacgag tttcatcgcc ttagccgttt
    27121 cctctgctaa ccgtccatat tcttccgctg ttttatgtcc aatctgccaa ggaccgtcca
    27181 tttcattccc taaacaccat gtcttaattc caaaagggct ctcttgacca ttcgaacgcc
    27241 ttaaatcact ccaataagtt cctttaggaa aattacaata ttcgactaaa ttacgagctg
    27301 catctactcc acgagtaccc agattgacag ccatattgat ttcggccccc acatgctgac
    27361 accagttata aaattcatga atcccaactt cattcgtttc aattgtccgc caagctaaat
    27421 ccaaccttct aggtctattt gctatgggcc caatactgtc ttcccaacga aatcctgaca
    27481 caaaatttcc accaggatat ctaatcatgg gaatgttcaa ttcttttacc aagtgaatga
    27541 cgtcttggcg aaatccactt ttattagctg atggatgatc tggctgataa atcccttcat
    27601 atactgctcg tcccatatgt tcaataaatg aactgtacaa ccgcggatca actttgccta
    27661 cacgcttgac actactaatc aacattgtgg cttccataac tgacctcctt taatttatac
    27721 atgaataata cacctcgttg aaagcgttgt caataatata aatgttaaac ttacttattt
    27781 tttatcgatt ttaattaacc aaaatattaa taatgattaa aacaaataat ttaatataac
    27841 ttttattaac aaatatgtta atatataaga aaaacctttt aagaggtgat atatatgcaa
    27901 ctacaaataa acgaagaatc cttaccggta tatgaagcat tagctagtaa aacaaggatc
    27961 aagatcatcc agctactttc caaaaaaaag atgaatgtca aagatttggc aaaagaactt
    28021 ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc tagaggaagc aaacatcatc
    28081 aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc gtgtcgataa aatcgatatc
    28141 agttttccag aaaaaatatt caatgctttt gatacgaaag aaacatcgat acctattggt
    28201 cactatacaa attatgcaat tgaaccaaca tgcggtttag ctacgatcca tgattttatc
    28261 gggaaagtgg atgaaccacg ctattttatg gatcctcgaa ggatggatgc ccgcattctc
    28321 tggtttacca gcggatttgt cgagtatcag gcacctaatt ttttaaatac agaggataca
    28381 ttggagatgt tggaagtttc tgtggaaatt tcttctgaat ttcctttttc aaatgacaat
    28441 tggccttcag atatcacttt cagcctaaat ggtgtggagc taggaacatg gacgagccct
    28501 ggagattttg ctgatatccg cggtaaatat acgcctgatt ggtatccaga taatcttaat
    28561 caatacggct tgctgaagac gatccgaatt accaaacact tgacgaatat gaatggagaa
    28621 cccttgtcaa acatcacgat caacgacatc cctaaagagc aagacacttg gcatttgcga
    28681 atcgaagtga aagacgatgc caaacatgtg gggggctgta ctttatttgg taaaggattc
    28741 ggtaattacg atcaggatat caaattaaaa gtttactaca gctgatattt ttcttttcta
    28801 ttttataaaa caaaaacagc caatccctat gaagggacgg ctgtttttgc tttattgtta
    28861 tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt ttatgttgtg tcttgttcca
    28921 ccatgcttcg attttttctt gtgcttgagc gggaacttct tttccttcta gataatcatc
    28981 aatttcatta tatgtgacac ctagtgcgac ttcatctgca atcattggtt tcccatcttc
    29041 aagatctgca gtcggaattt ttgtgtataa tttttccggt gcattcaatg cttgaagcaa
    29101 ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa atgtcggctc caccatcacc
    29161 aaatttcgtg aagaatccag taatgttttc tgcagcatga tctgtcccta atacggctcc
    29221 tgctctttct ccagctacgg catattgcgt aatcatacgt tgacgtgctt tgatatttcc
    29281 tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat acttgtactt gtgcatcaac
    29341 agctggtttg atatttactc gcagactaac atcgggctgg ataaagtcaa gagcagcttt
    29401 tgcatcttct tcatctgctt gttcaccata aggaagacga acagcgataa attgatagtt
    29461 ttcatctttt gtttcttcac gcatttcttc catcgttagt tgcgccaaac ggcctgctaa
    29521 agtagaatct tggccgccgc tgatacctag tacaaaagtt ttaagaaacg gatatttttt
    29581 caaatatgct ttcataaagt caatactttt acgtatttct tcttttggat caattgttgg
    29641 tttgacacct aattcattga taatttctgt ctgcaggctc atttattctc ctcctatgct
    29701 tctgtatgaa gttctgctac gctttttttc attcgttcca tgatagccat tttatggttc
    29761 cagcattcag tagacagatc gactgggtat ttttgcggat tcaagtctcg tttatactct
    29821 tcccatagtg aatctagatt ttcttttgta tattctttga tttcgtttag tgcaggtaat
    29881 tcgtaaactc tttttccttc gataaagata tcttgtaaaa ctgggcgagc tgtaaagtct
    29941 cgaacagttt tattgataaa cgtatgcact ggatggaaca tgaagatagc ttcttcttct
    30001 cgagggtctt catcccataa tgtcacgtag tctccttcag atttcccatc aaaatttcga
    30061 gtgatgcgcc acacttgttt tttccctgga gtagttactt tttctgcatt gcttgataac
    30121 ttgatcgtat ccatcatttt tccttcatca tcttcgatcg atactagctt gaatactgca
    30181 ccaagggctg gctgatcata ggctgtgatc aattttgtcc caacacccca tacatcaatt
    30241 ttagcttttt gcatctttaa attcaaaatc gttgcttcat ccaagtcatt cgaagcatag
    30301 atttttgctt ccgtaaatcc ggctgcatct aattgttccc gaacacgctt agatatatag
    30361 gccatatctc cactgtcgat gcgtacgcct tggaagttga ttttgtcacc taattctttc
    30421 gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat cataagtgtc gactaagaac
    30481 acgcagtctt tatgggtttt agcgtaggcc ataaatgctt cataatcatt tccataagat
    30541 tggactaacg aatgagcatg ggtcccgcta gctggtatcc caaatatctt cccagcacgt
    30601 acattgcttg ttgcatctgc tccgccgata tatgccgctc tagttcccca gactgctgca
    30661 tccagttctt gtgcccgtct agttccaaat tccaatagtg gatcttctcc gatgacagat
    30721 ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat tgaccatatt caacagtgct
    30781 gtttctacta attggcagtg cgctaaaggc ccttccactt ggattaatgg ttcatttgca
    30841 aaaactagtt ctccttcacg agcagaacga actgttgctt taaattcaaa attttgtaaa
    30901 tactccaaaa aaccttcagg atagacttct aatccacgca agtaagcaat atcggaatca
    30961 ttgaacgtca gattctctaa ataattgact aaccgttcca atcctgcaaa aaccgcgtat
    31021 ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa cagcatgtaa atcagctcga
    31081 cctaattccc agtatgtctg catcatattg atttgatata gatccgtatg cagcgtcaaa
    31141 ctgtcgtctg ggtaagtatt attcatcttg tattactcct cttggcaagt tttcatttcc
    31201 tacccattat aacaaaaaaa attaatagga aaagaaatct tccatttttt ctgaaaaagc
    31261 acatgtttta cggatatttc ttg
//
LOCUS       DAZAOD010000018        30589 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000018 DAZAOD010000000
VERSION     DAZAOD010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.019"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(11..1594)
                     /gene="abc-f"
                     /locus_tag="ACHDPO_000946"
     CDS             complement(11..1594)
                     /gene="abc-f"
                     /locus_tag="ACHDPO_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFN3368591.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(1699..1827)
                     /locus_tag="ACHDPO_000947"
     CDS             complement(1699..1827)
                     /locus_tag="ACHDPO_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368592.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(2172..2315)
                     /locus_tag="ACHDPO_000948"
     CDS             complement(2172..2315)
                     /locus_tag="ACHDPO_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFN3368593.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(2538..3017)
                     /locus_tag="ACHDPO_000949"
     CDS             complement(2538..3017)
                     /locus_tag="ACHDPO_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFN3368594.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(3090..3374)
                     /locus_tag="ACHDPO_000950"
     CDS             complement(3090..3374)
                     /locus_tag="ACHDPO_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368595.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(3452..3646)
                     /gene="ssrS"
                     /locus_tag="ACHDPO_000951"
     ncRNA           complement(3452..3646)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACHDPO_000951"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(3718..5004)
                     /locus_tag="ACHDPO_000952"
     CDS             complement(3718..5004)
                     /locus_tag="ACHDPO_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFN3368596.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            5142..5813
                     /locus_tag="ACHDPO_000953"
     CDS             5142..5813
                     /locus_tag="ACHDPO_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFN3368597.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            5779..6267
                     /locus_tag="ACHDPO_000954"
     CDS             5779..6267
                     /locus_tag="ACHDPO_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFN3368598.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            6280..7227
                     /gene="prmA"
                     /locus_tag="ACHDPO_000955"
     CDS             6280..7227
                     /gene="prmA"
                     /locus_tag="ACHDPO_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFN3368599.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            7228..7992
                     /locus_tag="ACHDPO_000956"
     CDS             7228..7992
                     /locus_tag="ACHDPO_000956"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFN3368600.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            8225..10438
                     /locus_tag="ACHDPO_000957"
     CDS             8225..10438
                     /locus_tag="ACHDPO_000957"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFN3368601.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            10449..10895
                     /gene="dtd"
                     /locus_tag="ACHDPO_000958"
     CDS             10449..10895
                     /gene="dtd"
                     /locus_tag="ACHDPO_000958"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFN3368602.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            11066..12325
                     /locus_tag="ACHDPO_000959"
     CDS             11066..12325
                     /locus_tag="ACHDPO_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFN3368603.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(12414..13361)
                     /locus_tag="ACHDPO_000960"
     CDS             complement(12414..13361)
                     /locus_tag="ACHDPO_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFN3368604.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            13755..15047
                     /gene="hisS"
                     /locus_tag="ACHDPO_000961"
     CDS             13755..15047
                     /gene="hisS"
                     /locus_tag="ACHDPO_000961"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFN3368605.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            15062..16831
                     /gene="aspS"
                     /locus_tag="ACHDPO_000962"
     CDS             15062..16831
                     /gene="aspS"
                     /locus_tag="ACHDPO_000962"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFN3368606.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            16940..17815
                     /locus_tag="ACHDPO_000963"
     CDS             16940..17815
                     /locus_tag="ACHDPO_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFN3368607.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            18081..19964
                     /locus_tag="ACHDPO_000964"
     CDS             18081..19964
                     /locus_tag="ACHDPO_000964"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFN3368608.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(20039..20323)
                     /locus_tag="ACHDPO_000965"
     CDS             complement(20039..20323)
                     /locus_tag="ACHDPO_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFN3368609.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(20313..21047)
                     /locus_tag="ACHDPO_000966"
     CDS             complement(20313..21047)
                     /locus_tag="ACHDPO_000966"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFN3368610.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            21176..21799
                     /locus_tag="ACHDPO_000967"
     CDS             21176..21799
                     /locus_tag="ACHDPO_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFN3368611.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            21991..23112
                     /locus_tag="ACHDPO_000968"
     CDS             21991..23112
                     /locus_tag="ACHDPO_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFN3368612.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            23119..26247
                     /locus_tag="ACHDPO_000969"
     CDS             23119..26247
                     /locus_tag="ACHDPO_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3368613.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            26266..29460
                     /locus_tag="ACHDPO_000970"
     CDS             26266..29460
                     /locus_tag="ACHDPO_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFN3368614.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(29606..30313)
                     /locus_tag="ACHDPO_000971"
     CDS             complement(29606..30313)
                     /locus_tag="ACHDPO_000971"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFN3368615.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT         9981 a         5561 c         6495 g         8552 t
ORIGIN      
        1 aaaaaacgtc ctagtcaatc agttggccga gcggctggcg gctgatctgc tcctgatcaa
       61 taacgagtgc ttcttggaag tgttgctgca aaaagtagcg gtcatggctg actgctagga
      121 gcgttccttg atagtcttgc agcatttctt caatttcttc tcgagcatag ctgtcgaggt
      181 gattggttgg ttcatccaaa atcaggacgt tgattttttc taaaaagagt ttcagcaacg
      241 ccaaacggat tttttcacca ccggataaat ctttgatccg tttacccaca tcgctttgat
      301 aaaagccact tttggctaat tgccgtcgag cgacttcttc gtttccagtc aatgtgatgg
      361 cgtaagccag caaacggcta tcgggatcgg caaactgcag ctgctgcggc aaataaccga
      421 tttgcaagct actacctaat ttgatggtgc caccgtaagg cttttcctca ccgagtaata
      481 atttgagtaa ggttgatttt cctgcaccat tgtcgccgat gatggctaaa tgatctccac
      541 gatagactgc aaaactgctg tctttgaata gtacttgatc agcgtactgc tggtgcaagt
      601 tttgaatgat gaaaacttct ttgccagatt ttccaccatt agacaagctt tgcagccgat
      661 ttttcggggg aggtggcggt ttgacgagtg tcagtttcgc caggcggcgt tccagttctt
      721 tggctttttt gaagaaggac tcattgtctc cttcatgtgc ccactgacga aaacgacgaa
      781 tcatgacttt caaccgctgg acttcttttt gctgcagttc gtaatttttt gtcagctcag
      841 ccaagcgagc ttctttcaag actcgaaaac ggctgtagtt tccgggatac tcaatcaatg
      901 caccttcttc cagttcccat gtttttgtgg tgacttgatc gagaaattgc cgatcatgag
      961 aaacgaccag aaccgatttt tttgtattct gtaaatagtt ttccaaccag cgaatactgt
     1021 taagatctaa atgattggtc ggttcatcga gtaaaagtaa atcggcatcg gctgctaaaa
     1081 ttttggctaa agcgacttta actcgttcgc ctccgctaag ttctgttaac cgtgcttcct
     1141 gacggtgtgg aatccctaag ccttgcaaga tcgctgcaat ccggtcttct aatacgtaac
     1201 cgcctagttc ttcaaagcga tgctgcagct caccgtaacg ggccagacac ttctctaagt
     1261 ttgtatctgg ttctgtcatc aatgcttcgt agcgactcat ttgctgtttg aggtcctgta
     1321 tctcagcggc agaatggagc aagtagtggt tgacggtcgc ttcggaaact gtaagttctt
     1381 gttcgaccgt cccgatcttt aagccttttt tgcgactgat aacaccgctg tcgacacctt
     1441 ctctgccggt caagatttgt aaaaaggttg atttgccagt tccgttgata ccgactaaga
     1501 caattttttc accagcttca atttgacagg ataaatcctc aaataatgga ttcccgccga
     1561 ttgttttttt aatagaaatt gcttgtatga tcatgatctc tctccttgag accactcaaa
     1621 aaggccatgg ttatccatgg cctgtgttat ttaaactcag attatcatga gaaaaatacc
     1681 ttgagatggc cattgatttt acgtgaattc aactgttttg gacaaacttg tcccgtcaac
     1741 agcaactgta aaaccaattg catggctaaa tgcgatatgg tatcgttggt aattttcatt
     1801 acttgttatt ttagtcatgc gcatcatagt attttccctc cttcgtgtag ttgtcttttc
     1861 cagtgtacct gaaagtgtca gaaagttcaa ctagcgctga catttactta atatttatcg
     1921 atgtgtaatt ctgtcagaga gcttttttta tctgactgag ggtaatgtct cgtggaccac
     1981 atcattgtat tctgagctaa accagcgttc aggcgaaatc atatggtgtt tgataaaaaa
     2041 ctttgtctac atgacttcct tttgccattt gcttaatacc gttgcattaa acagctcttc
     2101 tctttggaaa tctcaccaac atcgcgttca ggagtatcgt tgtggttgca atggcaagcg
     2161 gtagcctttc atcaattctt gaatgattta ccgaatgtag cacttgcctt ctcgcggtac
     2221 ccgaacccga aataaaattt tagtttggcg ataaaatcgg tatccgccat cgatacttca
     2281 tattttttcg tatcagattc atcggaaact tccacattga cgaaccaata agctttggca
     2341 tgcttaggtc gttttaaacc acaccagggc gactaatcgc cctggtgttc actttttttt
     2401 attttacttg aactcattga ctgttttccc tttattttaa acattataaa gaccgatgag
     2461 tgcttgccgc gtcttttgtt tttatcacgg ttttttgtgc aaaaaaacct gccgatagtt
     2521 ggcaggtcgt ctacgtgtta agctttggtg tggtctttag ctggcaattg gttttctaaa
     2581 tcagttcgga caacaagcac atcgcaagct gcgtttctaa taacatattc agaaacagaa
     2641 ccaataaata aacgttctac agcattcaat cctgtggctc ctaacataat caaatctact
     2701 tgattatctt ctgggatttc tctggcaata atttgttttg gtgagccata ttctacgaca
     2761 gaggttacat tattcaagcc agctttcttc gcattgcttt cataatctgc caatgtttgc
     2821 tttgccattt cagtagcttg ttctgcaagc attccatcaa aggatgaaac ggtttggaaa
     2881 gaacgtgtgt caatgacatg tgctaataga agttctccgt tatttcggat agctacattg
     2941 accgcctttt taaaagctaa ttcagcttca tcagaaccat ctacggcaac catgattttt
     3001 ttgtattgtt gtaacataag cattcactcc tcaagtcaat cgtattgtac tcttttattg
     3061 tagaacactt tagggaaaaa gagaattatt tactgctttg gttcagcaat tttttttgca
     3121 aatcggatac tgaaggtggc agaaacaata attacgatca gtaaaaagac caaggcaata
     3181 aagcgttgat tgaaaaaagc tgttaaaata cccattacgc ctaaaacagc atatgcagct
     3241 ccgtaaaatt gtaggaatcc ttgattttta tcatttttgt tgatcaatac aaaaaagata
     3301 tcctgtttat taaataaata atagctaacg aataataata ctaaagtggc gataatcatt
     3361 aaaatcctaa tcatgaacaa atcctccaaa ataagcaaca aatagaaaaa gcaatttgcc
     3421 aagagcaaat tgctttattc tttaaaagat ggtaatctcc gttaatgccg ttgtttgtcc
     3481 tgtagtattg atcccgcgaa ttcaagcagg tgggtcccat ggtcgtagct tcgaactacc
     3541 aaatgataag gcatgttacc agcagtgaca caagacgggt cccaagatat caataaaaat
     3601 gttcggtcaa cacacaaaga ggacaattcg aacatcacag atttcccacc tctatagtag
     3661 catatgaatt taaaaagagc aatgagagag ctcgcagaaa cagaaccgtt ttcttgtcta
     3721 gttttttgga ggatgctttt tccactcttt tatacggtaa tactgttgac ccagagcctg
     3781 ttcatatttc cctgtatctt ttggctgata atactgagca ttcttcagtt tatctggtaa
     3841 atattgctga ttgacccaag cctgatcaaa atgatgagga tactgataac ccacgccacg
     3901 gttgagtgat ttcgcacctt tgtaatggct atctctcaaa tgatcaggaa catctccagc
     3961 tttgccctct cgaatatcag caagtgctgc atctaatgcc atgtaggcag aattggattt
     4021 tggcgacaag caaagatcga cgacgacgtc tgctagtggg atacgtgcct caggcaatcc
     4081 caatttttca gcagctaata cagcgttcac tgtacgagcc gcagcagcag gattacctaa
     4141 acctatatct tcataaccga taaccatcag acgccggcaa atacttgcca gatcacctgc
     4201 ctcaactaaa cgggcgagat aatgaagtgc agcatccaca tcacttccac gaatcgattt
     4261 ttgaaaagcc gaaataacgt cataatgagc atctccattt ttgtcatggg taagagcttt
     4321 tctttggaca cattcttcaa tgatcgacag tgtaagatga atccttcctt ctttatctga
     4381 aggagtcgat agtgtagcca gttccagccc attcaatgca ctccgcaaat cgccgttcgt
     4441 tgcacgcgaa aggtgaagaa gagcatcttc gtctaactgg attgcttgtt gtccaaggcc
     4501 gcgttcttta tcccttaaag catgttcgac tgccaactgg atgtcttgtt ctgttaatgg
     4561 tttgacttca aagatctgtg tacggctgcg gatcgctgga ttgatggtaa tataaggatt
     4621 ctcagtagtc gctccgatca agatgattcg gccactttct aaatgaggaa gcagaaaatc
     4681 ctgttttgtt ttatctaatc ggtgtacttc atccaataag aggatcactg taccactcat
     4741 ttttgcttct tccgctacaa cttgtagatc cttttttgaa tctgtagcgg cgtttagcat
     4801 gcgaaatgca taattagtag agccggcgat cgcacttgcg atactcgttt ttccagtacc
     4861 aggaggtcca tatagaatca tggaagagag catgcgagca tcgaccatgc ggcgtatgat
     4921 ttttccttcc ccgactagat gctgctgacc aacgacttca tcgatcgttc gaggtctcat
     4981 gcgataagcc aatggctgtt gcataggatt ttcctccttc ttgtttttac gtcccttaat
     5041 tatatcatat ttagcaagat gcctagaaag aacagccttc tgttgttttg ttttcatagc
     5101 ttatccaact aatattgtgt atgataaagt aggtgagaaa aatgacggat aaacaaaaga
     5161 tagatgaatt tttttggaat aaaacgacgc cagaagtggc acgggattta ttggggatgt
     5221 atttggagca tgacacacca gaaggaagat tagctggata tattgtagac gcggaagcat
     5281 acctaggtcc agaagacgag gccgcccata gctatggttt aagaagaaca ccgcgtgtgc
     5341 gggcaatgta tgaaaaacca ggtacgatct acctttacac gatgcatact catcggattt
     5401 tgaacatcat tactcagcca gaagggattc ctcaaggagt aatgatacgt gcaatcgaac
     5461 ccgccgcaat gattgatcaa atgagtaaaa atcgtggcgg aaaaactggt ccagatatca
     5521 gcaacggtcc gggaaaatta gtggaagcat tagcaattcc tcaagaactt tatggtcagt
     5581 ctatagcaga tagttcgtta cgcttagttt ttgagaaaaa aaagacacca aaaaagatca
     5641 atgctttgcc tagaatcggt atcccaaaca aaggtgtatg gacagaaaag ccgttgcgtt
     5701 ttgttgtgtc gggaaatcct tatatctctt tacaaagaaa aaaccaaatc gagaaagatt
     5761 ggggttggag gaaagaaaat gaaaaagaag gatctattaa catatttaga tgaaataatt
     5821 gaaaaacaag tgacagacta tgatgtagct ttagattggg atacaaaaaa tcatacgatc
     5881 gagatcgttg ttcgcttgtt tgcagaaaat aaagcacaat ttgagattga tgatgcagaa
     5941 gggatcgttt cgcaagaacc aattatcgaa tttgaagacg gcgtacttct ttttaatcct
     6001 cagaaatctg tttttgatga acgcaattat ctagcagtaa tcccttatga aggaaaaaaa
     6061 gggttggcaa aatcagtagc tgattcttta gtggaatatc taaatgaagt attagctcaa
     6121 gggcaaagcg atttgcttga ttttttggat gaagacgatg acgaagctgt attcgagctt
     6181 cactgggata atcagcaact agcagaatta gtagaagtaa aacagcaaaa tgaagcagat
     6241 acttatttac cgtacccaag ttattaagga gtgacagata tgaaatggaa tgaagtaaaa
     6301 gtagaaactg aaagtgaagc agtcgaagca gttgctaata ttttgatgga ggcaggggcg
     6361 agtggtgtcg cgattgaaga ttctttagat gttgaacatt ttcagtcgga tcaatatggt
     6421 gagattttag ataaaaatga ttttacatcg ctgaaagaag gcgcactagt catggcttat
     6481 tttccggaaa cgactttctt accggaaatc ttgcctttta tcaaagatcg tatcacacaa
     6541 ttacctgagt ttggtctagc tattggaaaa aataaagtaa cagttagtga agtagaggaa
     6601 agcaactggg caacagcctg gaagaaatac tatcatccgg tgcgtattac gcgaatgctg
     6661 acggttgcgc caagctggga aaactaccag acagaagatc ctctagaaaa aattatcaca
     6721 ctagatcctg gtatggcatt tggcacaggc actcatccca cgacttcctt gacattgaca
     6781 gcactagaaa cagtcttgcg tggtggtgaa acattgctag atgtgggaac tgggtcgggc
     6841 gtgctaagta ttgcagcaaa atatcttggt gcaaaagatg tctatgcctt tgatttagac
     6901 gaagtagccg ttcgttcggc gaaagaaaat atggatatga atgaaatagc caaagatgtc
     6961 catgtatcag ctaacgatct tttgacagga atcgagattg aaagtgatgt aatcgttgcg
     7021 aacattttag cagatatcat cttattgatg atcccagatg cttggcgttt actgaagcaa
     7081 acaggcacgc tgatcgtttc aggaatcatt gaagagaaga agcaaatggt tctggatgcc
     7141 atgttagaac aagggtttat cgtggatcaa attttccagc aaaaagactg gtatgcaatt
     7201 attttgaaaa aaccagaggt ggaatagatg cagcggtatt ttttaaaaga atcatatgaa
     7261 tcaaaagact attttgtttt agaaggggaa aactatcacc acattgtacg ggttatgagg
     7321 atggaacccg aggatgaagt ttttttggca ttcaatgatc aaatagccat tgttgcagaa
     7381 atcacggaga ttactgaaga ggctgtttat ctgaaagaaa ttaaaaaaga agaaaatcaa
     7441 aaggaactgc caagttcgat taccatagcg agtggctatc ctaaagggga aaagctggat
     7501 tggatcgttc agaaatccac tgaattagga gcgcaagctt ttcttggttt cccggcatca
     7561 gcctctgtcg ttaaatggga tgcaaaaaaa cgtatgaaac gacaacaacg gcttgaaaag
     7621 attgctcaag aggcagcgga acaatcccat cggcagatcg tgccatcagt agagttattg
     7681 gaaacgaaac aagatttatt tgagcggcta gatgattatg acgtggtctt ggttgcttat
     7741 gaggaatcag caaagcaagg cgaaaaatca aatgcagcca aaattcttag tgaaacaaaa
     7801 ccagatagtc gaatcttagc tgtctttgga ccagaaggtg gattatcccg cgatgaagtc
     7861 gattattttg tagaacacaa agggatactt tgtggattag gaccaagaat ccttcgtaca
     7921 gaaacagcac ctctttattt attaagtgct gctagctatc aatgggaatt aatgaatcct
     7981 tctttcagct aacgttcttc attaataaaa gagtatcgac agaaagaatt gaaaaaatag
     8041 tcaacaattt gtataataga aacaattatt tatacaatgg atacgaaaaa tcgtttgaaa
     8101 aagcttttaa aaagcgaaca tttccgtaaa aaaacgtata actgcacgga ttttgggaca
     8161 attatcaaac agatatttgt cccgattccc gttttaccga aaaaagaaag ggggatcgat
     8221 tcctgtgaca aaagaagaaa ttttaacggg acccggtgtc ataaagctcg ttagtcaata
     8281 catgggtccc gaacatgtag catttgttga gaaagcatgc gaatacgcga ctgctgcaca
     8341 tgacggacag tttagaaaat caggcgaacc ctacattatt catcctatcc aagtcgcagg
     8401 tatattagca gatttaaaaa tggatcccca tacagtggct acaggcttct tacatgatgt
     8461 tgttgaagat acagaaatca ctttagaaga tctgagagaa gaatttggcg atgacgttgc
     8521 tatgttagtg gacggcgtaa ccaaattagg gaaaataaaa tataaatccc acgaagagca
     8581 gctagcagaa aaccaccgaa agatgctgct agcaatggct caagatttac gagttatcat
     8641 ggtcaaatta gctgatagac tacataacat gcgtacgttg aagcacctgc gagaagataa
     8701 gcaaagaagg atcgctcagg aaactttaga aatctatgcg cctcttgcac atcgtctagg
     8761 gatcagccgg atcaaatggg aattagaaga tacagcactt cgttatctaa atccaaaaca
     8821 gtattaccgt atcgtccact tgatgcagac gaagagagaa gaacgtgaaa aatacgtaag
     8881 tggtactgtt gaagatattc gaatagcgac agaagagctg gggatttttg cagaaatcta
     8941 tggacggcca aaacacattt attcaatcta tcgtaaaatg aaagatcaga aaaagcagtt
     9001 caacgaaatt tatgacttgc tagctattcg agtgatcgta gattcaatca aggattgtta
     9061 tgctgtatta ggagcaatcc acacaaaatg gaaaccaatg cccggcagat ttaaggatta
     9121 tattgccatg ccaaaagcta atatgtacca atctttgcat actaccgtga tcggtccggc
     9181 aggaaatccg gtagaaattc aaatccgaac acaggaaatg catgaaatcg ctgaattcgg
     9241 ggttgctgca cactgggcct ataaagaagg aaaaaatgaa aaagtagaac cagatggtat
     9301 gacgaaacaa ttaagctggt tccatgagat actcgaactt caagacgaaa gctatgatgc
     9361 ttctgaattt atggaaggcg taaaaggaga tatctttagt gataaagtct acgtcttcac
     9421 accaaaagga gacgttactg agttaccaaa aggatccgga ccattggact ttgcatacag
     9481 tatccataca gatatcggta acaaaaccac tggtgcaaaa gtaaatggca aaatggtgca
     9541 gcttgattac aaattgaaaa acggagatat cattgagatc atgacttctc caaattcatt
     9601 tggcccaagt cgcgactggt tgaaattagt tgctactagc aaagcaagaa ataagatcaa
     9661 acgtttcttc aaagcccaag atcgagaaga aaatgtgatc aaaggccacg aatccgtggt
     9721 caaatgtatt acagatctag gatttacgcc taaagatatt ttgacgaaga acaaactgca
     9781 agaagcactc gatcgtttta attatcaaac agaagatgat ctctatgcag ctgtagggta
     9841 tggagaagtt agccccttga cgatggccaa tcgtctgact gaaaaagaac gtaaagaaca
     9901 aaaaatcgag cagcaaaagc aagaagcaga agaaatcatg aatcagccga aaaaagaacc
     9961 tgacaaaatg aaagtacgtc atgaaggtgg cgttgtcatt caaggggtag aaaacttact
    10021 aattcgtatc agtcgctgct gtaatccgat tcctggtgat gatatcgttg gttatatcac
    10081 taaaggcaga gggatatcca ttcatcgtcg agattgtccg aatgttcagc ctgacaaacc
    10141 aaatgtagca gaacgtttga ttgaagtcga atgggaagat acatcgaata cacgaaaaga
    10201 gtatgatgca gatttggaaa tttacggcta taatcgttca ggcttattga atgatgtact
    10261 tcaaacagtc aatgcgctaa cgaaaaatct caacagcgtt gaagcacgga cgaataaaga
    10321 taaaatggcg acgatccatt tgacggttgg tatccagaat ttatcccacc taaagagtat
    10381 cgtggataaa atcaaagcag tacctgatgt ctacagtgta cgccggacga atggatagga
    10441 ggacagatat gagagcagtt gttcaacggg taagtaaagc tgctgtgtca gtcgatcagc
    10501 aagaaattgg aaaaattggc tacggcctac ttgttttatt aggcattcat gaaaccgata
    10561 cgcaaaaaga tgtggactat ctggtaaaaa aaattgcaca aatgcgtatt tttgaagatg
    10621 aacaaggaaa aatgaatatt agtgtagaag atgtgggagg acaaatttta agtatctctc
    10681 aattcacact gtttgcggat acgaaaaaag gaaatcgacc aagctttgtg gaagccgcac
    10741 gaccagaaac agctattcct ttatacgaat cattcaatga aggaatcaga agtcgcggca
    10801 tcacagtcgc taccggacaa ttcggagcag atatgtcggt ttctctcgtc aatgatggac
    10861 ctgtaacgat cattattgat tctaaaaaca aataaagtaa tctggttttc actagtaaaa
    10921 actatgaaac acgtcgctta agttagactg ataaactcta acttaagtgg cttttttgtc
    10981 tgcaaaaagc gcttcttttg tcagcagtcg gaaaaaaagt taagcttaaa ttatacaagt
    11041 tattttttat aggaggttgc tgaagatgaa agaagtacca gtagtagata tcaaaatcac
    11101 agatttaaaa aaattgtatc aaaaaggata caacatgttg gaggagttac gccatgaagc
    11161 ggacgctccc gtcgtcaaag caaagatttt caataaagaa gctatcacga tctacggatc
    11221 atcagcagca aaagtatttt atgatccaag gaatttcaaa cgaaaaggtg ctatgccaaa
    11281 attagtattg aagacacttt ttggtcaagg tggagtacag actttggatg gagctgctca
    11341 tcaccatcgg aaaaatattt ttatggatct aatgacaccg gaaagaatgg aagattatca
    11401 tcgtatctta gataagaatc tgacacaagc acttgaagca cagcatggtc aatttgaact
    11461 atttgattta agtaagatgg ttttctttac atctatttgc gagtgggcag gtatcaattt
    11521 atcagcgatt tctaaagatg aggtcgaaaa attagcagaa tatcaaatct ctatgatcag
    11581 cggaacgttt acttctccga ttgatcacat aaaaggtgtc gaaaatcgca aaaaatcaga
    11641 aaaatgggcg caaggcttga ttgaagaagc tcgacaaaat cctgtggctg gaaaagaaaa
    11701 tgtggcatta tatgcttttg ccaatgccac agatttagat ggtcagcttt tacctctgga
    11761 agtggcagct gttgaattat tgaacatcat ccgtccaacg gttgctctaa ctgtgtgggc
    11821 ggcattgatg ggacatgcac ttttcagtag accagatttg tatcagcaat taaaaaatga
    11881 cttttcgacg ttacaagatc cgtttattca agaaatgaga cgctattatc ctttcttccc
    11941 aatgctacct gcgatttcgc tgaaagaagt agaagtagat ggttatcgta taccagaagg
    12001 cagttgggtt attttagatt tatatggaac agaccatgat gaacgaacag ttgaagcgcc
    12061 agattccttt atgatcaaac ggtatgtagg gaaagcaaaa gatatttcct ataaagaaga
    12121 atatgagatg attgcacaag gcgggggaaa ttttcgacaa atgcatcgct gtgcaggaga
    12181 atggatcact cttcatagtc tacgtgtgtt ttccgatcag ctagtaaata agtttgagtt
    12241 ctctgtacct gaacaagatt ggacgattcc attcaatcag tttccgactt atccgaatag
    12301 ccgagcgcta ctttacaaga attagattag cataaactta tcgaaaaaaa ggaagatcaa
    12361 acagtgctga tcttcctttt ttcatattac tataaattga taaggtcaat tgatcaaaat
    12421 ccacgaaatg cttcatcaat ggtttgataa tcttcattgg ataaatgcaa atctaaagct
    12481 tggacattgt cagatacttg ctctggacgc ttagctccag gtataactac agacactcgt
    12541 ggattcttca tgtaccaagc taaaacaagt tgcgcaggag tggcttggta tcttttagca
    12601 atggggcgaa gtacatcgac agcggttaaa atttctctga aacgttctcc ttggaaatct
    12661 ggatttcttt ttcgaggatc tccttcacca aattgttttt cctcaccaag ttcatatttt
    12721 cctgtcagca aaccggaagc aagaggaaaa tagggaacaa aactgatttt gtttttttca
    12781 agataaggga ataattcttt ttcagcctgc cgatggatca aactgtattt atcttctact
    12841 acatcgacat atccatctgc attcgcttct ttcaattgtt ctaacgtgaa gtttgacaca
    12901 ccgactgctc ggatttttcc tgcttctttt aattcgtgca atgtagcaac tgattcattt
    12961 tttggtgtgc tttcatccgg aaagtggata taaaaaatgt cgatgtaatc agtttgcaga
    13021 cgttttagtg catcttccac cgattgtttg agaaactcag gagaattatc aaatgttcgc
    13081 cctttatttg gtacatgagc agcttttgta gcgatgacga cacgtgagcg atcatattct
    13141 ttttccttca gtacctcgcc aatcagttct tcggaacggc cgtttccgta agcataagcg
    13201 gtatcgatca aattgatccc gctattcaaa gctgtacgaa ctacttgttt tcctgtctca
    13261 tcttccaaac cgtcaaaaag attatgtcct ccaacggcat ttgctcctaa tccaagctgt
    13321 tctgcgtaga cttgtgaatg tccgattctt atttctgcca tagctgattc ctcctttttg
    13381 tctagtctaa aacaaaatac caaaaagctg aactaaaacg tttttgtgag gggaaatagt
    13441 cagatatctc ttgactttga gactggtttt tagtaggtta taagtaatat cgaatgtcaa
    13501 tgaaagagcg agtaagtttt tgaaacttta caagagagga tcatcgaggc tgaaaatgat
    13561 ctaaagtttc attagcctaa agacactctg gagatggacg agtgaaaagc cgtcccgcgt
    13621 acgagcgtta ttcgtaagag gaaagagaaa tctttcaaaa ttaggtggta ccgtgtatga
    13681 atttcattca cccttgttca tgatgaacaa gggtgatttt tttatttaca tagctaagaa
    13741 agggagagaa aactatgagt ttccaaagac caaaaggaac aaatgatatt ttgccaggcg
    13801 aatcagaaaa atggcagttt gtcgaagaaa cagcacgttt attattcaga gattatcagt
    13861 ataatgaaat gcgtacaccg atttttgaac actatgaagt gatatcccga agtgtagggg
    13921 atacaacgga tatcgtttca aaagagatgt atgattttta tgacaaaggg gaacgccatg
    13981 tgacgcttcg accagaaggt acagcaccaa tcgttcgttc ttttgttgag cataaattgt
    14041 tcggcccaga gtatgcgaaa ccgttcaaaa ctttttatat gggaccaatg tttcgctacg
    14101 aacgccctca aaaaggacgg ttacgtcaat tccatcaaat cggagtagaa gcatttggat
    14161 cagaaaaccc tgcaactgat gtggagagca tggtgatggc acttgatttc ttcaaacagt
    14221 tggggatcac gcaaatccgg ctagtcatca attcattagg tgataaagaa acgcgtcaag
    14281 cctatcgtca agcattgatc gactatcttt taccttttga atcagagctg agtgaagact
    14341 ctaaacgccg ccttcatgaa aatccattac gcgtattgga cagtaaagac aaacgagatc
    14401 aaaaatttgt ggcagaagct ccatctatct tagattatct aagcgagcct gctcaaaaac
    14461 attttgatac cgttgtttcc atgctggatg cattggctgt tccttatgaa atcgacagta
    14521 atatggttcg cggactagat tattacacac atacgatttt tgaaatcatg agtgacgcac
    14581 caaaaatggg ggcacaagca acgatttgcg caggcggacg ttatgacaat ctagtggaag
    14641 aactaggtgg tccttcaaca cctggcttcg gatttgcaat gggtatcgag cgattactct
    14701 tgactatgga ggcagaggaa gtagttatcc ctgcatttaa tgagttggat gcttacgtgg
    14761 tcgcactcgg agacgaaaca aatatcgaag cattgaaagt ggtccaagcg attcgaaact
    14821 ttggtttttc agctgaccgc gacttcatga accgtaaagc aaaagcgcaa tttaagacag
    14881 cagataaagc gaatgccaaa ttagtattgg tgatcggtga agatgagctt gctagtcaaa
    14941 cgattaatgt caaagcaatg gcaagccgaa aagaaaaaag ttttccatta gaagagatat
    15001 atgaacattt tgatgaagtc tatgatgaaa tgactttatt cgagtaggag gaaaaaaata
    15061 aatggcacaa agaacgatct attgcggatt agtttccgaa caacaattag aacaaacagt
    15121 tacattaaaa ggatgggtac aaaaaagacg agaccttggg ggagtaatct ttatcgacct
    15181 acgtgatcgt gaaggaatcg ttcaaatcgt ctttaatcct gaaatcaaca aagaagcatg
    15241 ggaaatcgcg gataaatgtc gcagtgaata cgtgatcgaa gtgactgggg aagttagaag
    15301 acgcggagaa aatgcagtaa atcctaaaat ggccactggt gaattcgaag tgattgcaag
    15361 tgaaatcgtg attttgaatc aagcaaaaac cccgccattt caaattgaag atgatcaagc
    15421 aatcagtgac gaaatacgtt tgaaatatcg ttatttggat ctgcgtcgtc caaaaatgac
    15481 taaaaacatc aaattaagaa atgcgacaac aaaagcgatt cgtcattatt tagatgataa
    15541 tgactttctc gatatcgaaa caccttacct agggaaatct acaccagaag gcgcaagaga
    15601 ctacctagtt ccttcacgtg tccatgctgg acatttctat gcgttgccgc aatctcctca
    15661 attgtttaaa caattgctga tgaatgctgg attcgaccgt tattatcaaa tcgttcgttg
    15721 tttccgcgat gaagatttac gtggagaccg tcagcctgaa tttacgcaag tagatattga
    15781 aacaacgttc ttaacagcag aagaaatcca aacttacaca gagggattga ttgcgaaggt
    15841 aatgaaagaa gttcgcggta tcgaagtcac attgccattt cctcgtatga cctatgatga
    15901 agcaatggct cgctacggca gcgacaaacc ggatacacgt tttgatatgg aattgatcga
    15961 tctaagcgat acagtcaaag aagtagaatt caaagtcttc caaatggctc ttgaaaacgg
    16021 cggtgtcgtg aaagcattga atgctaaagg cgctgcagat cgctactcac gaaaagacat
    16081 ggatcagtta ggtcaatatg taggacaatt cggagctaag gggcttgcat ggctgaaagt
    16141 agaagaagac ggattgaaag gtccaattgc taaattcatg ggagaagcaa cagaagcaat
    16201 cattaaagca acagatgcaa aaccaggtga cttgctgatg tttggcgcag ataaaagtga
    16261 aatcgtcgct gctgcattag gtgctatccg gacacgttta ggaaaagaat taggactaat
    16321 tgatgaatcg aaattcaatt tcttatgggt aactgattgg ccacaatttg aattttcaga
    16381 agaagaaggt cgatatgtct ctgctcacca tccattcacg atgccaaaag aagaagatat
    16441 cccgttattg gctgaagacc ctgcaaaagt ctatgcagaa gcttatgata tcgtcttgaa
    16501 cggttatgaa ctaggcggag gttctatccg tattcatact cgtgagcttc aagaaaaagt
    16561 actagaaact ctaggcttta caaaagaaca aatggaagaa caatttggtt tcttgttaac
    16621 agctttagat tacggattcc ctccacatgg cggtattgca ttaggattgg accgttttgc
    16681 aatgttatta gccggagaag ataatattcg tgaagtcatt gcctttccta aaaacggaaa
    16741 agcagcagat gtgatgagtg atgcaccaag tatggtttcg cctttacaat tgttcgaatt
    16801 gaatattgat gtaacgaata tagaagaata gccgataaaa aggtaaaaag gatttgtcga
    16861 atacgcttct tttgacaacc ttgatttaat tgaaaaacac tttataatga agccataaca
    16921 tataaagcgg ggcttttcca tgaaaaaaac attcgaaaat tgggcttatc atgattacac
    16981 gaccaagctt tcggtatcta tcgtttatgc gttgatcgca tcagtcgcat tgaatttctt
    17041 ttatcagcca ggacatattt attcaagtgg tattactggt ctagctcaga ttttgacgac
    17101 tttgtcaaaa tcactgatag gattcgaagt accggtatca acaactttgt atttactgaa
    17161 tataccttta tttgtattgg cgtggttaaa aatcgggaag aagtttacaa ttttcacttt
    17221 tatcacagtc actttgacct ccctttgtat ccatatttta ccggaaacag tcctatctac
    17281 cgatccaatc atctgtgcgt tgtttggggg ggctgtgatg ggactaggta ttgggctagc
    17341 gttgagaaac ggcctatcat cgggcggtct agatatcgtg agtatcacga ttcgtaaaaa
    17401 aacaggaaag tcgattggtt ctatttcgat ctacttcaat gcattgatcg tttttgttgc
    17461 cggaattcta tttggctggc aatatatgtt ttacagtacg ttgtctattt tcgtcagtgg
    17521 aaaagtaact gatgtcgttt atactaaaca aaagaagatg caggtaatga tcgtaacgaa
    17581 acatccagaa aaagtagtaa atgaaatcca aaactgtatg cgtagaggga tcacgatcat
    17641 caatgaagca gaaggtgctt ataagcatga taagcagaca gtattgatga cgatcgttac
    17701 acgatacgaa ctgcctctac ttagagaagc aatgaaagct tctgatccac aagcttttgt
    17761 aagtattgca gaaaacgtcc agatacttgg tcgtttctat gaggatggca tttagatcga
    17821 gtttgacaaa aattcatgaa atactgctgt agacagacgt tcgtttgtct gcagtttttt
    17881 tctaccatag tagaatcagc aaagaaaaac tgctttttta tttgaaattt tcttaaagtt
    17941 gaaaaaaagc atgtttattt ttttaaattt atgggatgat agaaaaaaat agtagagaaa
    18001 ggacacgatt ctacttgcta ttttcactta atacccgtat attacgaatg aaaaaagttt
    18061 atgaaaagtt ggaatattga atggaaaaac aaaaaaggtt aaaaaacagc cgctacatca
    18121 ctgggtttga tgggctccgt tcattagctg tggtgggtgt tatcttctat caccttctgc
    18181 caactagtat gaaaggcggc tatttgggcg ttccgatttt tttcgtcgta tctggttatt
    18241 tgatcacgga tctgctgcgg caggaatggg aacaaaatgg aaaaatcaat atttggcaat
    18301 tttatgtcag aagaatgaag agactctatc cggcacttgt ttttatgctt gtgacagctt
    18361 cggcttatat cactttgttt cagcgagggc tgttaaacaa tcttcgagga gttgtggtca
    18421 gcagcttact gtatgtcaac aactggtggc aaatcaataa cggtttatct tatttcgatc
    18481 gatttgctaa tgagtcaccg tttacgcata tctggtcttt agcagtagaa ggtcaaaact
    18541 atttggtttg gccgatcttg tttgtattgt tgatggtatt tgttcgtaaa agaaaatgga
    18601 tcttttatac tgtgttaggt acatccttcc tctccgccat cttgatgatg atcttgtata
    18661 caccaggagg cgatccaacc cgtgtttatt acggtaccga cactcgtctg ttttctatat
    18721 ggttgggaag tgcgcttgcg tttgtttggc caagtacgcg tttaaagaaa aacatcccga
    18781 aacaagcgaa aaatattctg aatatcgctg gaggaatctc gcttttggca ctgattcttt
    18841 gcttcttctt tttagatgat cattacaatt tcatctatta cggaggaatg ctcctagtga
    18901 gtctgttatg cgtagtgcta gttgcagtga cagcacaccc cggagcaagt ttgaatcgat
    18961 ggctgacaaa tccagtattt acttggattg gcaaacgaag ctatggcatt tatctgtatc
    19021 agtttccagt tatgattttt tatgaagcaa aggtgactga tattgccgat catgttttgt
    19081 tgcatacttt agtggaaatc acattgattc taatcatcag tgaactttct tatcgatatg
    19141 tggagcgtcc gctagcacgt tttgattatg gtcgtacatt ccaagtgatg aaaggatggt
    19201 tcagcaaacc gatcatcagt aagagcaaac catgggttgt tccaggcaca ttacttgtag
    19261 caattgcact cgttggtttc gttacggcac cgaaaaacgc tgtaacagcc gatcaaaaac
    19321 aactgcaggc aaaaatcgct gaaagtaaaa aattagcaga agaaaccaga aacaattcag
    19381 aaaacaccac tagttcggtt gaccaagcga tccttgataa gtacgagttg tccaaggcac
    19441 aagggaataa ggcacaaaaa ttagaactaa cggcatttgg tgattcagtt atgttggatg
    19501 ctgcaacgga tctacaagaa ctttatccaa aagtagtggt agatggagat gtcggacgac
    19561 aattatatgc cagtgtaccg tacattgaaa aattaaagga acaagatttg ttgaaagaca
    19621 ctgttctgat cggactagga acgaatggct cattctcgga agctcagttt gatagtgtga
    19681 tggatgcaat cggtgatcga aaagtatact gggtcaatgt ccgagtaccg acgaagcgct
    19741 ggcaaaatga cgtgaatgcg atgcttgaac agatgacgaa aaaatacgac aatatgacgc
    19801 tgattgattg gtacagctac agtaatgacc atagtgactg gttttatgat gatcaagtcc
    19861 atccaaatcc tgaagggatg acacattaca ttcacttagt cagcgaagcc ttgctaggag
    19921 gaagttcaag tacgaacagc agtgagacaa acgtgacaga atgatagcta caaaaaactt
    19981 caggcaaaaa catttgtttt tgcctgaagt ttttttatat ttaccgtgtt tttaacattc
    20041 atatagattc aggaagcaaa acggttgagt gtgtctgtaa ataacgttct ttttgttttc
    20101 gggtgagttt tttgaatgca gcttctgctt ttgttgcttc gcttcttgaa gaaaatactt
    20161 ctgcatggat catcttaaca ggtcttcttt tttgaagacg agtatattta gcaccagtac
    20221 cattgttatg ttcctctaat cgtctagaaa gatcggttgt atatccacca taaaatgtct
    20281 gatctttaca gaataatacg taaaaataat gttcatttgc catagagcat ctcacgaatc
    20341 tctgcagtgt attctccatc catattgtaa gtgatcaatg gtggagcgac tttgaatccg
    20401 tctaatttgc cttctttgat tccttcaact aacaaaatat ttgcctcttt tccaggtttt
    20461 gggtaaacaa attggatcct tttaggtgca attcgatagt cttccatgac ctgaatgatt
    20521 tctaagaacc gatcaggacg atggaccata gtaaagcgtc catttgtttt tagtagctta
    20581 cttgaaatat cgatcacttc ttctaacgtc gtatgaatct catgacgggc gattgccagg
    20641 tgtttattag ggttcgtttt atttgttggc agccctttga aataaggtgg attacagacg
    20701 actaagtcac aagaattatg tcgaacgaca gataagctgt ctttcagatc gatggtgtgg
    20761 acagtcattt gttcatttaa atggttaagc gcgatactac gtcttgccat gtctgctaga
    20821 cgaggttgaa gttcgatagc gtcgatagcc gcctgggttc gtttacttaa aaaaagtcca
    20881 actgcgccat ttcctgcaca aaggtcaaca atcttccctt ttttaggtac acgggaaaag
    20941 tgagcaagca gcacagcatc taaagaaaaa gaaaacactt tggaactttg gataatcttg
    21001 atatcttctg cgtataattg gtcgattcgt tcgtcttcgt gaagcatgga ttccctccaa
    21061 aatgaaaaaa atagtcgtct gtattatact atttttatta aaaagaacca aggtggcttg
    21121 tcaaacctct attttttatg catactatga ccataagaag ggaaaggaag agactatgtt
    21181 ttatcgattt atgcgcgggg tagttcgagt actattagcc ttagttaatg gaaatgcccg
    21241 ctatgagaat aaagaagttt taccgcaaga tgagaattac atactagttg ctccccatcg
    21301 tacttggtgg gacccattat atctggcggt agctgcagca cccaaggaat tcagctttat
    21361 ggcaaaagaa gaactgttca aaaatccagt tctgcgattt atattaactc gatccaatgc
    21421 ttttccagtt aaaagagaaa atccaggacc aagcgtcatt aaaacacctg taaagatttt
    21481 gaaatcgaca aatttgagtt tgatcatgtt tcccagtggg acaagacatg ctacagaact
    21541 taaaggcgga atggcattga tttccagaat gtctaaagcg aaaatcgtgc cagctgtata
    21601 tcaaggtccg ttgacacttg gggatctgtt caagcgtcag agagtgacag tgcgtttcgg
    21661 cgaaccaatc gacttatcag atatcaagaa aacggataaa gaaggtatgg cggagatcga
    21721 acgacgaaca caagcagctt ttgacaaatt ggacaaagaa gtgaaccctg atttcaaata
    21781 tgaagtcaaa aaaaaataaa atgataagtt tatgcgtggg cggtcttttg aatctactgt
    21841 cctgttcagt tcagactttt tcaatgaaaa cgagggagag acgtcaagtc tgccctcttt
    21901 ttgcgttcca atatgtaaaa tagaagacag gtgtcatgta atggatcaaa gtgttataat
    21961 aattagaagg acattttttg aggtgattga atgcgttttt tacatacagc cgattggcat
    22021 atcggaaaaa aactacaagg ttatgacttg attgaagacc agcgtcatgt actatcttct
    22081 atactagata tcgcgaaaga agaaaaagta gaggcaatcg tgattgccgg agacttatat
    22141 gataggagtg tcccagctgt tgatgccgta gaattataca atgaattgat ggtcgattgg
    22201 aatttaaagg aaaagatccc gatttttgct atatcaggaa atcacgatag cagtacgaga
    22261 ctttcagcgg gtacgccatg gttcagttat tcgaactatt ttttgcgaac acagctagca
    22321 gaagcatttg aaccagtcga gtttaaaaac gtacaatttt tctttcttcc ttactttgaa
    22381 ccaattgcag cgagattata ttttgaagat gacaatatcc gaacgatcaa gcaagcggta
    22441 gccaaggtga tagataaaat gcaggagcta tttgattcag aaaaaaaaca agtattgatt
    22501 agccattttt ttgtaatggg aagtgtaaaa tctgattcgg aaacgaaaat cgaagtaggc
    22561 gggttggatt cgatccctgg tgaactactt acaccgtttg attatgtagc actaggacat
    22621 ttgcataatc aagctgcttt gagacaggat aatgctcgct atagcggttc cccattgaaa
    22681 ttctctttat ctgagatcaa ccaaaaaaaa ggcgtatgga tcgttgacct gacaacaggc
    22741 ctggagttga attttaggga gatcgaaccc ctgcatgata ttgaagaaat aacagcgagt
    22801 ttcaaagaat tgctggatcc tgccttttat cagtccgtca atcgggagaa ttacatctat
    22861 atctatctca ctgatagaac gatcatcccg aatatgatga accagcttcg gcaaatatat
    22921 cctcgtattt tggggattga acgggcaaac ggtcgagcag aacaaacaaa gcgcaaacga
    22981 aaagtactag aaatgaaaga tcctcaaaaa ttagcagaag cattttttag tgaaatgacg
    23041 gaagagcagc taactgcaaa ccaagaaaaa tggctcggag aaacgttgca agaaatcatg
    23101 gaaatggaat gatcaagaat gaaaccgaaa aaattacaac ttaaaaattt tggtcctttt
    23161 atcaatgaga ccgtagattt ttcacgtttg acagaagcac cgcttttttt gatcagcggg
    23221 aagacaggag ctggcaaaac gacgattttt gatgggatca ccttcgcact ttttggtgaa
    23281 acttccggaa gacttcgctc tggaaaagag atgcgttctt tgtttgctac accagacgaa
    23341 gaaacaagcg tgactttttc ttttgaacat cagcagatga gctatgaaat cgaacgaaaa
    23401 ccagaacaag ttttagcaaa acgaaaagga aacggaacaa aaaaacaggc agccaaagta
    23461 acgttgacca tttttgatgg gaaaggaaaa gaaataaaac aaatcacaaa acgtacagaa
    23521 gcagatcagt tgatcagaga actgatgaat ctcgatgcga aacagttttc tcaaatcgtt
    23581 ttactacccc aaggagaatt ccgtaatttt ttggtttcat caagcagtga taaagagact
    23641 gttttacgtc atttattcgg tactcaattt ttccaacagt tcaatgagcg attaaaagaa
    23701 aaagcaaaac aacagcaaca aaaattggat catttagagc aagagctgca tcttctgcaa
    23761 aaaaggtttg ttttagtcaa agaagaggaa ccagcagcag ggtttgaagc cgttttagcc
    23821 caatggacaa accatcaggc aatactcgaa aaacaaatca cggaagaaaa agaagctcta
    23881 acggaacttc aggaaaaaca aaagcaacta gaaaattcct actatcgttt tgaaagcttg
    23941 aaaaaaagtt atgaagaaaa aacgatatta ataaacaagc aaaaggaatt agctgctcaa
    24001 aaagacgaaa tagaggaaaa gaaacgatgg attgggtatt atgaatttac gcaacgatta
    24061 gtcgaaccaa tccagcgcct acaagaaata aaagttgaaa aaatagaact gtcacaaaaa
    24121 agtagtgagc aaacaaagaa actagcgatg actacgcaga attatgaaga gtggcaaaaa
    24181 aatgaagcaa accgcgtacg ccgacaaaca aaaatcaaag aagctgctca aaaactgcaa
    24241 aacaaacaga tgatggtgcc aattgtcgaa tccttacgta gtaaaaaaca agacgcagaa
    24301 caattaacaa tttcattgga taaagaagaa ttgaatgccg agaagctgta tcaaaatctc
    24361 gctatctatc aggaaagaac tcgaattctt caagaaaatt tactggatca ggaaaaactg
    24421 caagaagatc gtcttgcttt tggacagtta aaatatctag atgaaaagca gcaagaaata
    24481 gaaaaacaaa aagcaaaaga cactgggtcg ctcgcacaga taagagaaga actcaaaaaa
    24541 gcaactgaag aaataacaaa aaatagtcag ctattgaaag aacagacaga acaagcagaa
    24601 cagctgaaaa gccaatgggc aaagcagcaa attgctcgtc ttcagctttt tttgcgtcca
    24661 ggggagccat gtcttgtttg tggatcaacg gaacacccca tacaacaatt aaaacacgaa
    24721 cagccaaata aggaagatat cttaaaagta gaacaacaac tggcagaagc tgagtctgct
    24781 gtagaaagaa ctcagcaaat cattgccaaa agtgaagcac atgaaaataa tcttcaacaa
    24841 caattatcag atttagaaca aaaaatcatg gcaacgaata tacaattggc tgaacaagaa
    24901 gaacacttgc aacaggcttt gaaaaaggca tttcctgaga taacagaaca aaaaacaaaa
    24961 acaactcttg tagtaatcga acaatcttta gatagacgaa aaagcaagat ggccaatgca
    25021 agaatagagc tggaagaaat aagacaacaa gcagaaaagc tcgaacaaca attagctgtc
    25081 tacaaacagc agcagacaga aaaaaataat cagctccagc aactgcaagg agaaatcaaa
    25141 agtttagaac aacaattgca agatacggat agtaactgtt tagaagagga gatacgacga
    25201 cttgaaaaac agttagaaga agactcgaat caactagctg ttgagcagaa agcaggagtg
    25261 caattgttgc aagatcttca tacgcttcgg acacagcttg atcttcaaca tgaacaaata
    25321 gaaaaaatag atgaaaaaat agaaaaggaa caagaaagaa tagctaaaaa gttagaaagc
    25381 cagtcgtatt tttcaacaat tgaagaaatc tgtgcatttg cacaacagca agcacaatat
    25441 aaagaaaacc aacgtacagt tacttcttat catgaagagc aattagtgac agctgaccgg
    25501 ctgcgtcaat tagaaaatat ccagctaact gagacattcc cagatacaga agagatcagc
    25561 caacagttag aagaaataag acgtatgatc gaaataaagc aagaaaagat atacggttta
    25621 caagaacaaa aaattagtaa tcaaaaaatc tacgatgaat gtctttcgat ttatcacaca
    25681 agccagacga aattagatga gcttacgcaa ttacagcagc tttcgcaaac attcaacgga
    25741 gaaaatccta agaagactag tttggaacgg tatgtgcttc aggtttatct tcaagaagtg
    25801 ttacaagtag caaatgatca tctccaacgt ttaacgaaaa atcgttatca atttgagcta
    25861 gcggatacca ttggcagtta tcgagggaaa accggattag aaatcaatat ctatgatgat
    25921 caggcaggta tgtctcgaag tgcgcatacc ctgtctggcg gtgagagttt tattgcagca
    25981 ctttctttag cattagctct tgccgatgtg atccagacac aagctggtgg tgtagcaatc
    26041 gatgcattgt ttattgatga aggatttggg tcattagatg aagaagcttt ggaaatggca
    26101 atggaagctt tagaaacgat cgaaagtgaa ggaagaatga tcggcatcat tagtcatgta
    26161 agagaattga aagaacgagt attacaacaa ataagaattg atacagaagg tagcggacaa
    26221 agcaaaatac gctatcaact tggataaaaa gggagattgg taactatgaa atggagtatt
    26281 ccagaaaaag tcattgcacg tggacgtcaa tacttgcaag aaggccgagt gttatcggtt
    26341 gtccctgacc aagaagaaaa cgtgtggcat gcagaagtct tgggcagtga attgtatatg
    26401 gttgatttgg atggtacagc aaaagagata gattactgcc aatgtcccta ttgggaggaa
    26461 cataaatatt gtaagcatac agttgctgtg gaactttatt tacggtcgaa aaatctatct
    26521 cgtatcatga aaaaagacca gccaatgcta gaaccggtaa aagcaacaag tgagggagaa
    26581 atcattgcaa aaggtttttc tcgtctaaaa acacaaaaca atcctcaagc ggtgcaacct
    26641 ttgattattg aataccaagt agaaacgatt gagactaatc agtatcaccc agagctttct
    26701 attttggcac tttacttgcg tatcggttca ttggcatcac cgaaaaaaac atatatcgta
    26761 aaaaacatct atgatttttt acaagcttac acagaaaaag aaacttacac tgttaataaa
    26821 cagtaccagt ttcgtctaga taaacgggcg tttcaaaaag aagatcaaaa aatactcacg
    26881 catcttgcag gaagtgctca gacgcatcaa ttattaggta cgaacggctt acaagtcaaa
    26941 ggaaaactag ataaaagata tctgcttctc ccagtagaac aagcccgctt cctgttagag
    27001 cagatgaatc agactacacg tttgcatctg cagataaatg aacaaaacga tcaaggaata
    27061 caattttccg atcaaaacaa acctttatca ttcaaagtgg aaaaatttgg agaagattat
    27121 ttgctgcaag cattgaatga ttttgatttt ttctttatgc attatcagtg gggagttatc
    27181 caagggacat tttattctct gacgaaatat caacaaacgg tttatcaaac ttggaaacaa
    27241 ttgattcgcc gattggagaa accagaagta gtgttcaaga aaaaagaatt accgtctttg
    27301 tttaaagaga ttatccctct gctgtcagag atcggcgacg tagctattgc ccctgcagta
    27361 gaagaggaag tagcagatat ccccgtcgaa tttattttct ttttccgaaa agcaaaagga
    27421 aaaatccaag ctcgagtcga tttcgtctat ggcgaagtca tctattcgac tgacccgaag
    27481 catgaggtct cgacagaaca ggcttttcag gtgttacgtg acacagtaga agagaaacga
    27541 gtacttgatc tattcagaat gtatcgctac cagaaaaatg aaactggtta tgaacgtcca
    27601 ttgccaagcg gggaagaact atatgccttt ttccgcacag aactatctgt cttccgtcag
    27661 tttggtgaag tcagacttgg aagaaaattg cgagagttgt atttagatgc gcataaacat
    27721 caaccgaaaa tcgaagtaac cgagaccggt tcatggctcg atattcgatt cgatgtgaca
    27781 gggatagagg agcaagaaat cgatcatgtc ctgcaaagct tgctgagaaa tgatgctttt
    27841 tatacattag aaaatggtca ggttctttct tttgattcag aagaatttca acaaacaagc
    27901 caagtgttgc aacaattacg ggaatcgata cgtacagaag aaggaacgat ccatgtacct
    27961 aaaaatcaag gattgatcat tcaaaatcaa ttggaaaaaa gcaatgctac ttttagtgaa
    28021 tcgttccaaa cgatggtaca agatctcatt catccagaaa gataccaggc acagcttccc
    28081 aaaggattga atgcaacgat gagagattat caaaagcaag gttttcgatg gttgaagatg
    28141 ttaggtcatt atcagtttgg cggtatttta gccgatgaaa tgggacttgg gaaaacacta
    28201 cagacaattg cctttttact ttcggaaaaa gaagaacgga aaagcttctc tgctttgatc
    28261 gtagcgcctg cgagcttaat ttacaactgg caggcagagg tgagaaaatt cgccccttct
    28321 ttaagtatcc aagtaatcaa tgggaataaa aaagaacgtg aagaattact ggctaaagac
    28381 acagatatcc gagtgacttc ttatgccagc ttaagacagg atctagctaa ttatcagtcg
    28441 caaaaaattg attatttgat tcttgatgag gcacaaatgg tcaaaaatag cagtacgaaa
    28501 actgcacaag cattgagaga attagctgta cctcagcggt ttgcactgag tgggacacca
    28561 atcgagaata atttagaaga attgtggtca ttgtttgcaa cgattatgcc aggatttttc
    28621 ccgactaaaa caaaattcag ggaacttgcc gcagaagaaa ttgcgcaaat gattcgaccg
    28681 tttattttac ggcgagataa acaaactgtg ttgaaagact tgccggaaaa aacagagatg
    28741 aatctatatt ctgcacttac agaagaacaa aaaactgttt atttagctta cttgcgtcaa
    28801 atgcgtgaag aaatcacatc aatggattct gaagcattca agaaaaaccg gatcgggata
    28861 cttgctggtc tgacaagact gcgacaaatt tgctgcgatc ctcgtctgtt tattgaagat
    28921 taccaaggcg gttccggcaa gctcgaacaa gtaaaagatc tactggtagc tgccaaagag
    28981 aacaaacgaa gagttttgct gttttctcaa tttacaggga tgctgactat cttgcaagaa
    29041 gagttagccg agctagggat ctcgacattt tatttaagag gcagtacgaa accacaagat
    29101 cggttaagta tggtagacgc atttaatgct ggcgaaaaag atgtttttct gatttcctta
    29161 aaggctgggg gaactggatt gaatctcacg ggagcagata cggtcatctt gtatgacctt
    29221 tggtggaatc ctgccattga agaacaagct gctggacgtg cacatcggat cggacaaaaa
    29281 aatgtggtag aagtgtggcg tatgatctct gaaggaacga ttgaggaacg catggattca
    29341 ctccagcaag aaaaacgcga actgttccaa aaagtgatcc aaggtaatga agaacagttg
    29401 acgaaactga ctgaagaaga catccgcatg attttaagtg taggagaaat cgaggagtaa
    29461 gagactcgaa aaagcgttca gtaatgggta agaaagcctt tctaaagaag cgattgttta
    29521 tttgatttaa aaaatagcaa ggaggctggg attccatttt atcccagctt ccttgctatc
    29581 atttttttat ttctattttt aaaggttata caaagattgt cttcattgtc tctaacagct
    29641 gatcaaaaga agaaatctcg atatcgcaaa ttggagtctg ttcaattttg cgttctcgat
    29701 ggttgaacca aagcgcttgc cagttagcac tttttgcacc tagaacatca ttgtcgtaat
    29761 tatcgccaac gtataaggtc tcttctggaa gcatatgaaa ttctttctca gctagctgaa
    29821 aaatctcttt ttctggtttt tggaaacctg ttgcttgaga aatgagcata ttgcgggaag
    29881 gaatccaatt gttcaattga agttgcttca gtttttttgt ctgatggtca gtcggcccat
    29941 ttgtgataat tcctaatggg acattctttt ccttcaagaa atcgagggtt tttttgacct
    30001 cctcatgcaa gcagatatta tcaagttctt cctcgtaaat tttttgaaat aagaggccat
    30061 cttcttccgt aatatgaggg tagtctaaat cttttagtga ttggctgatc cgatgtgctc
    30121 gcatatattc tagtgtccaa tctcctgcca ttacttttgg gaagttttca tcactatgat
    30181 ggcggaaccg gatatatagt ggatgcatat ctgcatctga aacaagcgga acgactcttt
    30241 tgaccgcgtt tcgaaatggc tgctgctgat catacatcgt atcatcaaca tcaaacacaa
    30301 ctgatttaat caaaatttta cacgcctttc ggttttcatt gattttttca caaatccttg
    30361 actattgtaa cagaaaaaat tgtctaaaaa agctgataaa taaaggtttt tcttactata
    30421 tttctatttc cttgacagaa taaggttttt atatttcagt ttttttcact aaaaatcgtg
    30481 aaacacgtca ataagtttga tgaacaaatt aatcattatg gtagaagtcg attgatttat
    30541 tttaatgcaa tctctgtgga attttcgaaa gatttatttt tttaataca
//
LOCUS       DAZAOD010000019        30223 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000019 DAZAOD010000000
VERSION     DAZAOD010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.020"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(57..635)
                     /locus_tag="ACHDPO_000972"
     CDS             complement(57..635)
                     /locus_tag="ACHDPO_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFN3368616.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(712..1242)
                     /locus_tag="ACHDPO_000973"
     CDS             complement(712..1242)
                     /locus_tag="ACHDPO_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFN3368617.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1246..2106)
                     /gene="rlmB"
                     /locus_tag="ACHDPO_000974"
     CDS             complement(1246..2106)
                     /gene="rlmB"
                     /locus_tag="ACHDPO_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFN3368618.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2099..2494)
                     /locus_tag="ACHDPO_000975"
     CDS             complement(2099..2494)
                     /locus_tag="ACHDPO_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFN3368619.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2491..3903)
                     /gene="cysS"
                     /locus_tag="ACHDPO_000976"
     CDS             complement(2491..3903)
                     /gene="cysS"
                     /locus_tag="ACHDPO_000976"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFN3368620.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(3900..4436)
                     /gene="epsC"
                     /locus_tag="ACHDPO_000977"
     CDS             complement(3900..4436)
                     /gene="epsC"
                     /locus_tag="ACHDPO_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFN3368621.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4522..4761)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4758..6218)
                     /gene="gltX"
                     /locus_tag="ACHDPO_000978"
     CDS             complement(4758..6218)
                     /gene="gltX"
                     /locus_tag="ACHDPO_000978"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFN3368622.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6388..7545)
                     /locus_tag="ACHDPO_000979"
     CDS             complement(6388..7545)
                     /locus_tag="ACHDPO_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFN3368623.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7579..8949)
                     /gene="radA"
                     /locus_tag="ACHDPO_000980"
     CDS             complement(7579..8949)
                     /gene="radA"
                     /locus_tag="ACHDPO_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFN3368624.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9012..9539)
                     /locus_tag="ACHDPO_000981"
     CDS             complement(9012..9539)
                     /locus_tag="ACHDPO_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFN3368625.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            9769..10575
                     /gene="proB"
                     /locus_tag="ACHDPO_000982"
     CDS             9769..10575
                     /gene="proB"
                     /locus_tag="ACHDPO_000982"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFN3368626.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            10572..11819
                     /locus_tag="ACHDPO_000983"
     CDS             10572..11819
                     /locus_tag="ACHDPO_000983"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFN3368627.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            11895..12239
                     /locus_tag="ACHDPO_000984"
     CDS             11895..12239
                     /locus_tag="ACHDPO_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368628.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(12356..12682)
                     /locus_tag="ACHDPO_000985"
     CDS             complement(12356..12682)
                     /locus_tag="ACHDPO_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368629.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(13297..14499)
                     /locus_tag="ACHDPO_000986"
     CDS             complement(13297..14499)
                     /locus_tag="ACHDPO_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3368630.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            14616..15131
                     /locus_tag="ACHDPO_000987"
     CDS             14616..15131
                     /locus_tag="ACHDPO_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFN3368631.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(15330..15776)
                     /locus_tag="ACHDPO_000988"
     CDS             complement(15330..15776)
                     /locus_tag="ACHDPO_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFN3368632.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(15823..17301)
                     /gene="msr(C)"
                     /locus_tag="ACHDPO_000989"
     CDS             complement(15823..17301)
                     /gene="msr(C)"
                     /locus_tag="ACHDPO_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFN3368633.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(17655..18284)
                     /locus_tag="ACHDPO_000990"
     CDS             complement(17655..18284)
                     /locus_tag="ACHDPO_000990"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFN3368634.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(18268..18732)
                     /locus_tag="ACHDPO_000991"
     CDS             complement(18268..18732)
                     /locus_tag="ACHDPO_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFN3368635.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(19219..20487)
                     /locus_tag="ACHDPO_000992"
     CDS             complement(19219..20487)
                     /locus_tag="ACHDPO_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFN3368636.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(20718..21455)
                     /locus_tag="ACHDPO_000993"
     CDS             complement(20718..21455)
                     /locus_tag="ACHDPO_000993"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFN3368637.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(21522..22091)
                     /locus_tag="ACHDPO_000994"
     CDS             complement(21522..22091)
                     /locus_tag="ACHDPO_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFN3368638.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            22219..23091
                     /locus_tag="ACHDPO_000995"
     CDS             22219..23091
                     /locus_tag="ACHDPO_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFN3368639.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            23433..24305
                     /locus_tag="ACHDPO_000996"
     CDS             23433..24305
                     /locus_tag="ACHDPO_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFN3368640.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            24302..26260
                     /gene="nagE"
                     /locus_tag="ACHDPO_000997"
     CDS             24302..26260
                     /gene="nagE"
                     /locus_tag="ACHDPO_000997"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFN3368641.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(26592..27443)
                     /locus_tag="ACHDPO_000998"
     CDS             complement(26592..27443)
                     /locus_tag="ACHDPO_000998"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFN3368642.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            27566..28033
                     /locus_tag="ACHDPO_000999"
     CDS             27566..28033
                     /locus_tag="ACHDPO_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFN3368643.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(28296..28778)
                     /locus_tag="ACHDPO_001000"
     CDS             complement(28296..28778)
                     /locus_tag="ACHDPO_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFN3368644.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(28878..29741)
                     /locus_tag="ACHDPO_001001"
     CDS             complement(28878..29741)
                     /locus_tag="ACHDPO_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFN3368645.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         8649 a         6388 c         5464 g         9722 t
ORIGIN      
        1 aaaaaaaaaa gaaatgcaat aaaaataaat aagaagctca ttaagatttt tctaaattat
       61 tcctcattat aaaatttcaa gtgttttttt attttgagtt ttactctccc gtaagcgctc
      121 attacttgct tgtgatccat tgctaaacat tcagccatgt ctacaaaatc aacgccttgc
      181 atataataat gaaaaatttt agcttctatt tttgaaaact ggatttcgca attttcgatt
      241 gcttctttta ataaaagatg ctgaattgct aaaggttctt gcaatgtgat ctctgctaaa
      301 aagtctggtc cttctgtctc tattttttgg tcgattgaga cttcatcttt ttgatcacga
      361 cgcttcagcg cgttctgctt cctcaacaga gaatagattt gattgcttat aacgctttta
      421 taataacttc caaagctaac acctttgctt ttttcgtaag ttctcaatgc ctgatataaa
      481 gcgatccttg cttcttgttc ccaatcctca gaaacataat ttcttaaata ataggtgttt
      541 ttcaaacgta gtaaaagtgg aaaatatttt tgatacaggg cagcaaatgc ttcttcgtca
      601 ccattacgtg cagcgcgcaa taactcctca gacataaaat aattcctcca taaattcgtt
      661 tatggaggaa tcttatcatc aatgattcat cgaactgatt agaacgatat gttatttatt
      721 ttttctcatt aaatcgtcca atttttggga caattttttt aactgctctt cattccatgg
      781 agaattacgt cggaaatcaa taaaatgcat atctttattt tcttgggcta ttgttttttc
      841 cgtttttttt atcgtcttat ataattcata agcagaagtt cgtaatgctc cttgggaaaa
      901 gatcatccac tgttctgcta aatcgcttgt cgccactgtc acttgtgtca aacggtcatt
      961 cagctgacca gcgattctct cgatataact gtcagccgtt tcgtcttctt tcgtaaaaac
     1021 aacatccaac tggtatttct tataattttg ttggatgccc ggaactagtt gggcatcgaa
     1081 gacaacgatg acttccattc cttcatattt cgcataattt gataaacgat gtaaaagagc
     1141 ttctcttgca tccgccattt tgtcctgctt tttaagctgg acaagttccg gccacgaacc
     1201 aatcatgttg tagccgtcta caatcaacag ctgttttttc atggtctact ccccctgacg
     1261 ttgggaaaaa gcctgataca taagcaaacc agcagcaaca ctggcattta agctctggac
     1321 gtgcccggtc atcgggatcg tcagcaattc atccatttct tttttcaatc ctggactcat
     1381 tcctttgcct tcattaccaa tgactaaagc aattgatcct ttggcattcc atttttggaa
     1441 gtttgtgccg gtcatatctg tgccaaatac ccaaaatcct gtttctttga gctgttgcac
     1501 agcttgtacc aaattcgtca cgcgtgcaac agggacatgt tcgactgccc cagtggaagt
     1561 ctttgttacg ataggtgtga ttccaactgc tcggtgtttt ggtatgatca caccatcgac
     1621 gccacttgcg tctgctgtcc gtaaaatcga cccaaaattg tgtggatctt cgatgctatc
     1681 caaaatcaaa aagaaggggt cttctttttt ctcttttgtt cgttcaatca gttggtcaag
     1741 ggataaatat tcataaggtg taatcgcaag aacgactcct tgatgcacgc cgtgatcgct
     1801 caaagtttct aatttttgtt taggaaccca tttgactggc acagcttgtt cacgtgcgat
     1861 ttctttcagt tcttctactt tttctcctcg tgaatcttct tgaagaaaga gtttattccc
     1921 tcgcccttgt tgtagcgctt ctactgcggc atggtgccca aagacgaaat tatcttctaa
     1981 tgcttcttca ttttgatcag aaactgactg atttcgtcca gtttgctttt tatttgaata
     2041 tctattttgt tttttgtctt caaatccacg tttcgattga tgtttgtttg ttctttcttt
     2101 acccattttt ttcaccaact ttctgaatac accagcggat caattcttcc atccgctcgg
     2161 tttgttttgt caaatgcaga tagcccatga gcgcttcgaa ccctgttgcg acccgatacg
     2221 tcgtaacatc agcatttttt gcgctcgtat ggcttttagc atttcttcct ctgcgataat
     2281 aaagttcttc ttcttctgtc aaaagatgtt cttccagcat ttgctgaatc aaaaaggctt
     2341 gtgcattcgc agaaacataa ttcgttgccg cacgatgcag cttattgggt tttgtttctc
     2401 cttgatcaat caggtggtca cgaacataga tttcgtaaat cgcatctcca acataagcca
     2461 aggctaaacc gttcaattgt gtgtaatctc tcatgcttct cttctccatc gggttccttg
     2521 cggtgtatct tctaataaga tccctttttc tttcaacaaa tcacgaattt cgtcgcttcg
     2581 gacaaaatca cgattgcttc ttgcttgatt tcgttcttcg atcaattgtt caatctcttc
     2641 atctaataac tcttctgctg taaataaaat accgaagatc gaaagccatt gcgagaataa
     2701 agcttctcct tgtgccaaga cagcggcaga aactttcggc tggtctagat aagtgttcag
     2761 ccacttagca agctcataga ccactgtgat cccatttgct gcattaaaat catcgtccat
     2821 ttcttcgatg aatcgctgtt ctaaattttc taacaaagcg attttatccg catcatctgc
     2881 caaattctct gaggcagttt cttggcggaa tttcaaattg tcaaacgtat tcttcagtcg
     2941 ttgtaaattg gtggctgctt ctttcatcgt cgtttcactg tagcggatcg gacgacggta
     3001 ttgtgtggtc gccatgaaga aacgcaagac ttgtggatca acgtttttga tcatttcatg
     3061 tacagtgatg aaattcccta gagatttact cattttttca tcgtcttcgc caatcgttac
     3121 atagccattg tgcatccagt aattagcgaa ttttttccct gttttcgctt cactttgtgc
     3181 gatttcattt tcatgatgag gaaattctaa atcttgcccg ccaccatgga tatcgatcgt
     3241 ttctcctaaa tgttttgttg ccataacgga acattcaata tgccaaccgg gacgtccttt
     3301 gccccatggt gaatcccaag aaatctcgcc aggttttgct tgtttccata aagcgaaatc
     3361 taatgggtct tctttttgct gctgttcttc ccctgtacgc tgacttgctc cgacttccag
     3421 ttcatcgatg gattggtcac ttaatttccc ataattttca aatttacggg tacggtaata
     3481 cacatcacct gaagattcat aagcatagcc tttttcaacc aacacttgaa taaatgctaa
     3541 aatatctggc atatgatcca tgactcttgg atgcagtgta gcaggttcga cattcaacgc
     3601 tttcgtatct tcttcaaatg ctcggatgaa acgatcagca acttctggtg ctgtaatacc
     3661 taattcgttt gctgtacgga tgattttatc gtctacatcc gtgaaattcg atacgaaatc
     3721 gactttatag cctcgatatt caaaatagcg tcgaattgta tcgaaagcaa tggtgctacg
     3781 agcatttccg atatggatat aattatacac agtcggtccg cagacataca taccgacatg
     3841 tcccttttgt atagggatga attcttcttt ttttctggtc aatgtattgt agatttttat
     3901 cattctgatc tcctcacttt ttctcctttg attcgaacga cttttgctgg tactcctacc
     3961 gctgtagcgt cgtctggaac atctttcaac acaacggcac ctgcaccgat tttggcgttt
     4021 tttccgatcg ttaccggtcc taatatctgc gcattcgcag agagcatggc tccttgttta
     4081 acagttgggt gtcttttacc cgtttctttt cctgtgccgc ctaatgttac gccatggaat
     4141 aaaatcacat cgtcctcgat ttctgcggtt tcgccaatga cgattcccat tccatggtcg
     4201 atgaacacgc cagttccaat cgttgctcct ggatggatct caacaccagt taggaaacgc
     4261 cagaattgag cattgatctt cgccaataaa aagagccggt gctgatataa aaaatgagag
     4321 aaacgatgcc aaaacaaggc atgaaaacca gggtatgtca aaacgatctc agctgtcgaa
     4381 cgtgcagccg gatcgtttct ctttgctgca tcaatcgctc gggtaaacca actcatgact
     4441 ttccactcct ttcgtaagaa ttttatgtag gaaatcatct tcttataaag aaaagaagcg
     4501 ccttttaaat aagtttcctt atcaaaagac gctttccgcg tggttccact tttcttcata
     4561 atcaatgatt atctctgaca gctaacgcct gttatacgtt cttggctact ttgtttccta
     4621 taaaacagtt tttcctgttt tctgtgtttc gccaagacca ctcccagagg catttcggca
     4681 accattcatt gataccttgc accacccggt atctctcttg taatgatcag ctgcttactt
     4741 ttttctgttc atcgtgttta gttcagtact tgatttaaat gtgctaatga tttttcacga
     4801 ccaagcaatt cgatcgtttc aggcaattct ggaccatgca tttgtcctga tacagctaca
     4861 cggattggca tgaaaagatt ttttcctttt acgccagttt ctttttgaac agctttgatg
     4921 gcagctttga cagttggagc atctactact tccatttgtt ctagctgtgc tttgaatgcg
     4981 tggagaacag taggaactgt ttcaccagca agtacttctt ttgctgcttc attcaataca
     5041 ggatgttcat tgaaaaatag cgtagacaga tcaacgattt ctgcagcata gctcatttga
     5101 ggttgataca ggctaacgat cttcttcacc cattcgattg tcttttcatc tgggttttct
     5161 gctacacgtc catcagcgat tagataaggc agacacatgt cagtaaatgc atctagatcc
     5221 attgctttga tgtaatggtt gtttacccat tgcagttttt tcgcatcgaa agctgcgggt
     5281 gatttactta ggcgttttgg atcgaacatt ttgatcaatt cttggtgttc gaagatttcg
     5341 tcttcgccca caggtgacca gcccaataat gcaataaagt tgaacattgc atctggtaga
     5401 tagcctaatt cgcgatattg ttcgataaat tgcaagattg attcgtcacg tttgcttagt
     5461 tttttacctg tttcactgtt gatgatcaat gtcatatgtc cgaaggttgg tggtgtccag
     5521 ccaaatgctt catagatcat cagttgtttt ggtgtattgg caatatggtc atctccacgt
     5581 aaaacgtgag tgattttcat caaatgatca tcgaccgcaa cagcaaaatt ataagttggc
     5641 ataccatcgc gtttttggat gacaaagtcg ccaccgatat tatcggattc gaacgaaata
     5701 gcgcctttca ccatatctgt aaatgcgtat tctgtattgc gaggcacacg gaaacgtaca
     5761 acagattcta gaccttgtgc ttctttttct gcttgttctt caggtgtcaa gttcgcacat
     5821 gttcctgcgt aatgaggcat ttctcctctt gcgcgttgtg cttcccgttc tgcttctaat
     5881 tcttcttctg tgcaatagca tttgtatgct cgattgctag caagcagctg atcaatcagc
     5941 ggttgataga tttctttacg ttcagattga cggtaagggc cgtattctcc aggattttca
     6001 ggagattcat cccaattcat tcccaaccaa gcaaggtttt ccaactggct tttttcgcca
     6061 tcttcgatat tacgtttttg gtcagtatcc tcaatacgaa taataaagtc tccatcattg
     6121 tggcgggcaa acaaataatt gaataatgca gttcttgcat ttccaatatg caggtgccca
     6181 gttggacttg gtgcatagcg tacgcgtact ttcgtcattt tcttcctctt ctttcaaact
     6241 agactttgac taacagcaaa aattccgtca gttacggctt ctcaaatatc atttatttaa
     6301 agccactcag cacaaatttt accttttcta aggtaaatag taaagccaac tggttgaatt
     6361 tccttaccag ttggctgaat ttctttttta ttttgattgt ttagtctttt tctctgtctc
     6421 ttttttattg tcgattcctc gtcctgcatg tgcaggttta gcaaagatca tgcgtccagc
     6481 agctgtttga agggcacttg ttacaacgac ttcgatacgt tcattcatgt aatgctgtcc
     6541 atcttctacg acaaccatcg tgccgtcatc aaggtaggct actccttgtt ggcgttctgt
     6601 cccggctttt actactagaa cattcatcgt ttcaccaggg atgacgactg gttttacggc
     6661 atttgccaac gcattgatat taagaacagg tacattttgg aattcagaga ctttattcaa
     6721 gttatagtca ttggttacaa tgacaccatc taaaagctta gccaatttga tcaatttgct
     6781 gtctacttca ctgatatctt caaagtctcc atcgtacatt tcgacagata taccctcttc
     6841 tttttgcaag gcatttagga tatctaatcc gcgacgacca cgcacacgtt tcaaactatc
     6901 ccctgagtcc gcgatgtatt gtagttcgta aagaacaaaa ttagggatca tcaaggttcc
     6961 ttctaagaat ccagtctttg taatatcata aatccgaccg tcaatgatca cgcttgtatc
     7021 caagatttta tatttatgga aattttctcc tgattttcgt tctaacagtt gactctcaac
     7081 ttgactagct gtttcttgct cgattttttt gcttcgtgaa ccaaaaactt tcttccattc
     7141 ttcgattcgt gtcgttccca ttctcaatcc cagatagcct aagatgatca tcagtaaaat
     7201 cggcaataca ctattgacga atggaatttc catattgtaa agaggggtcg agatcacaac
     7261 acctaaagtc aatccgatga tcgcaccgat cgcaccgaag agaagataag tcaagctgac
     7321 ctcacttagt ttttgttcta cttgtttgat aatagctgag atatgtttgg ccaacagcaa
     7381 agataataaa aagaaaataa gtgcgcctaa caggctgttg gtaaatgtat tattcagcca
     7441 tccgtttgac tgttgaccga ttgcctgcca agctgagggt aaaaatgaaa tacccaagct
     7501 tgcgccgaca atgatcatca gcaaagtaat gacacgtttt tgcatcgttt ttcctccgtt
     7561 tcgacaatca tttattagtt agcggaacac acgcttcaac gtttcagcca aagttgctac
     7621 tccaactatc tcgattcctt ttggcgcttc ccagttacct aagttgtttt taggtaggta
     7681 tacttttgtg aagccgagtt tttggacttc tttgactcgt tgttcaatat gactgacacg
     7741 tctgatttct ccagtcagtc caatttcacc gatgaaacat tccgttggct gtgttccttt
     7801 ttctttatag cttgaagcaa tactgacagc gatagctaaa tcaatcgctg gttcatttaa
     7861 ttttacccca cctgcagctt ttaagtaagc atcttgattc tgaagaagca acccagctct
     7921 tttttccagc actgccatga tcagagatac ccgattgaaa tcaagacctg ttgttgttcg
     7981 tttggcattt ccgaacatag taggtgtgac taatgcttgg atctctacca aaattggacg
     8041 tgtcccttcc attgccacaa cgatagcaga gccagttgca ccgtctaggc gttcttctaa
     8101 gaaaatctgt gaaggattag cgacttcttc caatccatgc tcatgcattt caaaaatccc
     8161 aatctcattc gttgagccaa atcggttttt tactgctcgc aaaatccgaa aactatgatg
     8221 ttgttcacct tcaaaatata acaccgtatc caccatatgt tctaacattc ttgggccggc
     8281 gatcgagcct tctttggtaa catgaccgac gataaaaatg gctatcccat ttgttttagc
     8341 ggttttgagt agttctgcag tggtttctct tacttggctg acacttcctg ccacacttgt
     8401 gatgtctggc tgcgtcatcg tttggatgga atcaatgata acataatcag gggagatatg
     8461 ttcgatggca cgactgattt cgttcatatc tgtttcagcg tatagataaa attctgtgtt
     8521 gatacttccg aggcgttccg cgcgtaattt tatctgctct gcgctttctt cgccggatac
     8581 atataagact tttccgccta tggctgctaa ttgctgagaa acttgtaaca gcaaagtgga
     8641 tttcccgata cctggatcgc caccaatcaa gaccatagac cctggcacca cacctccgcc
     8701 taacacacgg ttcagttctt ctaattttgt tttgatccga ggttcttttt tagggacgac
     8761 gtctgcgatt tttgttggtt ttgctttttc tcctgtcaaa cttgtccgag ttctgcggtc
     8821 cgttgtatct tgttcgattt cttcgaccat cgtattccat tttccgcaat ttgggcagcg
     8881 tcccaagaac ttaggcgaca catacccgca attttggcaa acaaattgta cttttgattt
     8941 ttttgccatt gtaccgcctc cttttatcct aatcatgaga cattaaatca agcttaagta
     9001 tctttaacgt tttatttact ggaagaacca aatccgcctt gacgttgagc agtcgtttga
     9061 tcttgatctg cttttaaaaa cggcaaaaag atcccttggc cgatacgctc gccttttttg
     9121 atcactacat ccttgaaacc aaagttggtg aattggaaca tgatatggcc ttcatttgcc
     9181 tcattattgt aataatcact gtcaatcaca cctactccgt ttgtcaacac taaaaaccgc
     9241 ttcaacggat tgcttgaacg gttagcaagc tgcaaaaatt catcttctcc catgtaagct
     9301 ttgattccag taggcacgag ggttggtttc aattgttttt cattttctga tacatctttt
     9361 ttcaatccat ctgcgactgt ttccaacccc tttttccagc ctgctttcca gatacttgga
     9421 atcacgacct cttctgctgc ttcaaaatca tagccagcag catgatgtgt agcgcgctgc
     9481 ggtagattga tattttgatc tttatattta gaaataactt caaatcctct ttttctcacc
     9541 ggttttcctc cctaaataaa ctactcctat tctaacatat ccgaggctgt aaaagacttt
     9601 ctttacaaat tcttcaagaa attctgctat cttaaagtaa accattaatt cgttcttttt
     9661 ccaaacgact gcaagttgta caaaaaaact attttttaca tgactttact cgtcaaaaca
     9721 agtagaatag aacgaaatta atgagtggat atttgattga ggtgtcacat gcgtaaagaa
     9781 attaaaaatg caaaacgaat tattgtcaaa gtaggaacaa gtacattgat ttatcccaat
     9841 ggaaatatca atcttgcggc aatcgatcag ttagcttttg tcctttctga tcttagaaat
     9901 cggggaaagg aagtgatctt agtctcatca ggagctgtag gcgttggtat gcataaatta
     9961 catttgtcag aacgtccgac tttgattcct gaacagcaag ctgcggcggc tgttggtcaa
    10021 gccgaactga tgaatatcta taatcaaaga ttcagtgtat ataatcaaca gacggcacag
    10081 atcctcgtga caagagacgt ggtagattat cctgaaagtc gtaaaaatgt gaggaataca
    10141 ttggaacagc ttttgattat ggacacgatc cctatcgtga acgaaaacga tactgtagca
    10201 gtggatgaat tagatcatct gacaaaattt ggcgataatg atcagctgtc agccatcatg
    10261 gcaaaacttg tcgcggcaga ccttttgatc gtcctttctg atatcgacgg gttttattca
    10321 gataatccga ctacaaatcc cgaggctcag atgtatcgct atatcgataa aatcgatgaa
    10381 aagattctgg cacaagcagg tggtgctggt agcacatttg gaacaggcgg tatgcagagt
    10441 aaattaaaag ccgcttctag gatatttgaa gcaaacagcg caatgatttt agcaaatgga
    10501 aaaaatccgg caattatttt tgatattctt gcaggaaaag aagtaggtac tttatttaag
    10561 gaggacttga aatgactgac ttgatgcaat taggacaaca ggcaaaagat agcgcgcaac
    10621 aactagcact tatgcctaca aaccgcaaaa atgagctact tgttcaaatg gcacaaacca
    10681 tcaaaaagaa tcaacaagcg atcattgaag caaatcataa agacttagaa aaagcagtcg
    10741 aaaacaatat cagtgaaacg atgcaagacc gcttgcagct gacacctgag cgaatcaatg
    10801 ccatggctac agagatcgaa aaaattgctt cgttagacga tcctattgga aaagtagatg
    10861 agatgtggac gaacaccgac ggattgagaa tcggcaaaaa gcgcgtgcca ctaggcgtga
    10921 tcggcatcat ttacgaatct cgtccaaatg tcacgacaga tgcagctagt ctagcattca
    10981 aatcagggaa tgccgttatc cttcgcggtg gcaaagaagc attcttctcg aatcaattat
    11041 tagtccaatt attgcagcaa gtactggtca gtgctggcga atctccttat gccatccagt
    11101 ttgtcgatga tacttctcat gaaactgcag gacagttgat gcgattgaca gaatacttag
    11161 atgtgctgat tcctcgaggc ggagcaaaat taatccaacg agtcaaagaa caggcaacgg
    11221 tacctatcat tgaaacaggt acaggaaata atcacgtata tatcgataaa gaagcacagt
    11281 tatctatggc agtgaacatc atcgtcaatg caaaagcttc ccgtccatct gtctgtaacg
    11341 cggcagaaac attgctgatc cattctgaga tcgcaccttt tttcttgcca gctattgaaa
    11401 aagaactggt agaacacggg gtctctttac gtgcggatgc tcgtgcgtta gaatatctag
    11461 agacggctgc tttagcagaa gacacagatt gggatactga atatctagat tatatccttg
    11521 ctgtcaaagt ggtcgattct ttggatgaag caattgcaca tatcaatcgg cataatacta
    11581 aacattcaga aacgatcgtg acagatagtt atgcggctag tcaacgtttc ttaaatgaag
    11641 tggacgcggc ggctgtctat gtcaatgcct ccactcgttt tacagacgga tcggtatttg
    11701 gttttggtgc agagattggt atctctactc aaaagttgca tgcccgtggt ccaatggggt
    11761 taaatgaatt aacttccaca aaatatatca tttatggcga tggacaaatc cgcgaataat
    11821 gtttcgtgtg aaacattatt cccgcctttt gccttttttc tgtaaaggtt ctatccaact
    11881 agaaaggtgt caatatgttt gaaattttaa tgattttttt tatttacctt atttctctga
    11941 atatcgctgc ttttctggga gtcggtattt tatccctttt ctttcaattc aaaaaacgaa
    12001 gcatagggag tcaacgggaa aaatggtcgc agtattttga caaaatcggg caaaaagggc
    12061 tggttacacg cttgcacatt agttacatgg ttgcattatg cttattagcg acaatcaatt
    12121 actattcttt tttcgatcat tcaatcgctt atacgattac gctactgatt gctgggattt
    12181 ttcacttatc ttataaatat cagctgaata aaaaccactt gaatcggact ttccgctaaa
    12241 aaatatccgt acgataagta gagtgccttg aagatcggca aaaaactgcc ggacttttta
    12301 gaggctgtga caaagatttt gtcacagcct ctttttccat ataaacggcg ttcgcctacc
    12361 agctgcctgg taaatctgtt tcctcttcgt taagaagcga aaatccgtca aatgtttcgc
    12421 catcataata acgaagcagc tcatccatgg acaagttcat cgttttttct ttttcttctt
    12481 ccgctgattc agccagtagc tgttcccgat acacctgata cataccagct attttttgct
    12541 gcatcgcttt tctagtttca ccttccgcat tgattattgg caattctttg atatagccac
    12601 gataaatcaa ccgatcatct gaaaattcaa tgggtaattc aacgagtgtc aacccgactt
    12661 cctgaaaata ttcttccagc atctattatc cccccattct ttttcttaaa tgaattttag
    12721 cttacctact gaaaattttc cagtttcatt attttgagaa aaaaagggaa tgtgacaaaa
    12781 atcgtgtcac atcccctttt tccgaataaa tggtgttctt ctgccaactc ctcaatcata
    12841 agtcacaata ttcaacaaac atgagaaact gttttttgaa attgttcctt gtgattcaga
    12901 gttaaacgac agtctcacaa cctcttggta aacggcgttc aatcagctga ccctcggtat
    12961 tagctcaaaa aacggtaaaa tatgagaagc tatttttccg ttttgtttct ctaatactta
    13021 ggataaaacg ctgattttac aacctctgtt aaacggtgtt caatcagctg tccttcggta
    13081 ttagctcaaa aaacggcaaa atatgaggaa ctatttttcc gtttgtttct ctaatactca
    13141 ggacaaaacg ctgattttac aacctcctga taaacggtgt tcaaaagctt gcatctgcgg
    13201 taataagccc aaccaaacga aaaatatgag aagctatttt tgtttggctg ttcttatgac
    13261 ttgatgcagg acagcttttt cacaacctct gatttcttat tcttcttcat ttgtagcaaa
    13321 ataattacgg tgataaatga tacaacatac actgataaga acaatggcac ctgcaaaata
    13381 aaacgcatag ctttcaccaa tatgttcacc aatcacacct gcaataaatg gtgctaaagc
    13441 tccaccgaaa aagcggacaa aactatagct ggacgaagca acgtttcgtt gcagacctgg
    13501 tatttccata gcaatcgtcg tcaacagtgt attgataatt ccttggaaaa atcctgctaa
    13561 cacaatgctg atcggtacaa ggactggcat agaagttcca gctcctaata acagcaaaca
    13621 aataatgaat aagacaaatg ctgctaaaat tgtccgataa gtcgtaaact tccgctcaag
    13681 agccggtgca acgaaaatcg aagcaatagc cagaagcaca ccccagccaa aaaatacaaa
    13741 accgacttct aattcagaat agccaatcaa taaaaatggc gcatacgcaa gtaaagtaaa
    13801 gaatccgaaa ttatataaca atgcgattag tccaactgaa cgaagtttat gattgcttaa
    13861 cgctttgaca ccttcccaaa ggcctacttt tctctttggt ttctcagttt caggtaaaag
    13921 taccgctagg gctataaaac cgcaaaacat caaaaatgct accccaaaaa atggataacg
    13981 ccatgaacca ctgcccaaga ccccaccgac tagagggcca acagccattc cgcagccaag
    14041 tgctgcttca tacatcatga ttgctttttc tgtgttacca actaaaatac tgacgatcgt
    14101 tgctaaagca gtagagacaa ataaagcatt cccgacaccc cagccggcac gtaacccaat
    14161 cagcattccg atattcccag ataatccgcc aagaccagcg aatacaacga tgataaacaa
    14221 tcctgtcatc aatgtttttt tcaaaccgat ccgactagat aagaaacctg taaatagcat
    14281 caccacacca gtgactaaca tgtaactagt aaataacagg gtcgtttcag ctggcgtagc
    14341 gtttaactgt gcagcaatcg tttttaagat tgggtctact agacccactc ccataaaagc
    14401 gatcatacag gtagctgcta caactagcgc tgaacttttc ccctttgttt cttcatttgt
    14461 ttgttcttgt atatctattt gattctccaa tatttccatc cctttctctc tattagcatc
    14521 atacatgatt tattttacat gtcaatatgc acatgtaaaa cgtggaaact ttactgtgat
    14581 ataataaaga aaataagacg agaggtagga tttttatgaa tactttagcc tatatattat
    14641 tatgcgtgct tttatccaaa ccacgttctg ggtatgaatt gaagcagctg atcacaattt
    14701 tttgggaagc ccatcacagt cagatctata caacgcttgc caagttagac cagcagggtt
    14761 atgtgaccgt tttggacaaa gacgagcact ctcaaaaaaa gatctaccac ttgactgatg
    14821 aaggacgtgc tcttgtagag gaatggatca aagaggaaac tcccgctcct acgcaaaaag
    14881 atgaatttct agcaaaaatc tatgcttttt cgacgctcga taaaacaaca gctactggac
    14941 tgctattcac tagagaacaa cagctgaaca aaatcatgca aaaaaatcaa aaaaaattga
    15001 atgacctctc gctagacaag aaacaagaat ttggacgtta tgttgtgatc cagcgcagaa
    15061 ttatgctttg tcagcaggaa ctccaatggt gtcagcaagt aagagaacaa atgcagcagt
    15121 tttttgagta agggataaac agaacctttc tagaaatatc tattgaagag caaattatct
    15181 tcaataaaag agcaatacag ttggaaaaga aaaagcgatc cgaacgacag gccaaaacct
    15241 atcgttcgga tcactatttt tctagaactg cattcaagag actatgacaa aaagcatgcc
    15301 aaggcctttt ttcaaataac agtgttccat cattcattac tttgaattgc ttttagcaca
    15361 cttcttgaaa gcgggccaac gatgatcaac tgcaacggta aagcggcaat cacattcatt
    15421 ttccaagcat tcatataagc agagaataat tgatcaggta ttccttgttc catgatcaca
    15481 ccgaataaag acatacatgt caccattcct aaaaccatca agcatgaaat agttaagatc
    15541 atttggacct tgctttctgg atttactggt agtttaaagg caattttttt cgccagcaca
    15601 ccgatgatga agacatccaa aatgaaagcc accacgaatc caggcactag accaatcaac
    15661 aaacttgata aatgaagatc ttgatgcagc cataaattat acgcgctcat ccccaagacc
    15721 atcaaaaaac acatcattgt tgtaaaaatt attccttctt ttttatttgt aggcaatctg
    15781 taccactcct ttaaatttgt cacgaaaatc atcgtagcac atttaaaaat ttctcgtaag
    15841 tacttttttt attttctgcc cttttatttc ataaacttca tcagccgtac gctcgacaaa
    15901 gtaagaatca tgagaagtaa acaaaatcgt tcccggatat atttgcatta gcttctctaa
    15961 agcttcgatc gttgccatat caataaaatt agtcggttca tctaacagca acacattact
    16021 tggcttagta aaaagcaaag caatcgtcag acgggtcgct tctcccccac ttaatgtaca
    16081 taacggtttc gtcaaagttt cctgagcaaa ccctaagtga ttcagcaaac tacggacaag
    16141 cgattctgaa aactctgttt gtctcatgac aaaacgaatg atggattctt cagatgtcat
    16201 ttgataaccc ttttgctgat atacttgaaa gcttactttc ggagagagaa ggattccttc
    16261 tccttgtttg cggatatgtt ctaataaggt tgtcttacct gaaccatttt caccgacaat
    16321 cgcgattttt ttacctaaag aaaactgaaa atcaccattt accagtaatg ttctcccact
    16381 tctttccaat tggacatttt gtcccatgat gggatagcgg ctgtggagtt caagagattt
    16441 tggtactgga aaacggattt gtttcatctg ctgcggcttg gttgtttctc ctattttttg
    16501 gagtcttctc tctaatgttt tcgcattctt ttggatggct ttttgtacac tgtctttttg
    16561 tttagaggaa gacaaccgat ccagtctgat ttgttgcttt ttctttttac tggacacttt
    16621 ttccaacttt tccgcttgtt ttttcttttc ttggatcgat ttttccaatc gttttttctc
    16681 tttcatgatc gactctgctt ctcgtagctg agtctttttc tccaattcct tttgagtgag
    16741 ataggcacta taattccccg aaaactctcg gatttctccg tcttttactt cccagatttt
    16801 cgatgctagc tcatctagaa aatagcgatc atgactaaca aaaaccagcg taccataata
    16861 ataacgaagc tcttcaatca gtcgatcaat actttttcta tctagatggg ttgttggctc
    16921 gtctagaagc atcccttgtt cataagaaga aagaagacgt atcaactcga tctttcgttc
    16981 ttcccctccg ctccatttcc gctctgaagt ttcttccagt cttaactgga aatgactggc
    17041 taattccaaa tttaggtcct ttgcttcagc gagataggtt aattgaggca ggtagttgaa
    17101 ggtgatctct gtttggattt tcccatgatc gggaaaaagt tcaccggcta ttagtttgag
    17161 caaagtcgat ttaccgacac cattttctcc tatgatccct atacgatctt gctgatagac
    17221 acgaagagaa tcaatagata gttctagctg gttgccaaag ctgacttgta gatttgttat
    17281 atttactgct aaattttcca tatgttttac actcctattt catgtaaaac aacaattatc
    17341 gatactaaaa aagagcagaa aaatctgttt gcaaaaaaac tgcatcacat cttttcctac
    17401 tctgaacgaa ataactatga ctaaatcacc aaatctgtca tagctttcac ctattctact
    17461 gtcgttcgaa aaaatggaca tactccatcc atgaaattgt tgtttataca tgtcttttga
    17521 atttatttag ttgttattca aaagttcgaa acgtaatttc atcgatgcag tcatttttcc
    17581 gacctccttt tttattaggt taccacacac gattcaaaaa aagcaatagc tactgaatag
    17641 taactgaaaa ccttttattc gaacatagtg atcttttctg gtgctaaacg aacagactcg
    17701 taaccttctt ctaccgcttt tcctattgat aaaataataa ctggaacata acggtcttta
    17761 tccaaaccaa atgcctctgc caactgatct gcttcgaatc caccaattgg atttgtttca
    17821 tagccatgat cacgcgcaac taacatgaat tgcatagccg ctaagctaga atcgactttg
    17881 actacatcgt tcatttcttc tcttgaaaaa ctcttgtaat aaggaatgat cgcagctaat
    17941 tgttgatctc tgacttcttt tggcatcttc cctgattcgt aagcttggtt gtagatttct
    18001 tcgccatatt cgtaacattg catatcgcca aaaatcatga ccattgcaga agaagtatca
    18061 ttttgtctcg tattgaaacg gatcaaagga cgcaagattt cttttgcttc ctcgctttca
    18121 gcgaccacaa agcgccatgg tttcatattg acagaagaag gtgcagtcgt cgcttctttg
    18181 atcatttcca gcatttcttc gtgtgggatt ttgtatgttt catcatatac gcgaacggat
    18241 cttctaccag tcataattgt tgaaaaatca tttttttgtt ccattattat taacctcttt
    18301 cgtttctgtt gttatattgc aaagttgggt attcaattta tctaaaagtg ttagaaattg
    18361 tttcatttct acatcgctga aagccgggga tagcacggaa cctgtatctt tatggtccat
    18421 ttcacaatgc ttgattttct tctgggcttt ttctgttagc gctacataca cttcccggtt
    18481 gttctgagga tttctctgac gcgaaacata gccatttgct tccaatacct tcagatgacg
    18541 agtaactgct ccttgatcaa tctgcaactt ttcttgcaaa ctgctttgta gcaatggatt
    18601 ttcttctttc agtctcatca tgatctcgta tctagtaaga cttataccga tattttcttc
    18661 aaagatctgg acgatttttt gatcggctaa tttgatttga tataaaaggt gactaatctc
    18721 ttctaaagac ataatttcct cctttctaat aattgactcg tcaacgattg acttgtcaat
    18781 aatagaataa aaaaagaaaa aagtcaaaga atcagctgtg taataaaaaa aacgctctca
    18841 atagaaaagt atagagaaaa gaaatttttt gtagaatgaa cggaaaaaat gataaagaaa
    18901 gcacaacgct aaaaccaaga ttattgattc ttatcaaact atagaagata gctcttctgc
    18961 agtagataat tttacaccgc caaaaatttc cgaaatcgcc ttttgcaaga atcccgtcga
    19021 atattagaaa ttggatcagt atgcttaaac agtaataaaa aagttatgac aagatgttgt
    19081 cacaaccttt tttgagtaaa cggtgttcaa aaacttgcat ctgcggtaat aagttcaacc
    19141 aaacaaaaaa catgaaaatc tgtttttgtt tggctgttct tactacttga tgcagggcag
    19201 ctttttcact acctcttttt aataaccata aaatcctatt ccttcatatc tccagcccat
    19261 cggtgttagc caatctcttt ccttagcact caaggtatag tgatgggtac cagttttttc
    19321 atttggatta aatagtcgat aaattggctt ggaaccacca gaataaaaac ttagaccttc
    19381 ataacgccaa ccgatttttg ttaaagagtt gatctcagat tgtgccattg tgtaatgatg
    19441 gtctccactg taaggattgt ataaacggta gacaggttgt ccgctgtttg gtgcttgcca
    19501 agcaatccct tcatattccc agcctacagt tggcagataa tttttttctc cggcattcaa
    19561 tgtatataaa tgttctcctg tatgacggtt atacagacga tacatcggag aagttgaagt
    19621 tggtgctgta tcatactgtg tcagattata ggtttcgatt acattgttca atgtagaacc
    19681 ataattaggc gcagtggcat aacgacctgt tagccaagcc gtagcatctt tgtaagagtt
    19741 cgtattgctt ttccatgcac cggaatagta gtaaacgcct ggctgaaaag aagtcgtctt
    19801 caataccgtt acgttatctt gcaatgattc tttgtacgaa ggatattttc taaaagcggc
    19861 attcaccgta atccattgcc cattcacata ttccgaagta ggcatcgtaa cagattggcc
    19921 attatagctt cctttaatcc caaatagatt gtaattaggg gcagaagcca aagtactgtt
    19981 cccccagcca ctttcaacga tggcttgagc aatcatgact gatgcatata agtcattggc
    20041 acttgccaaa ctttgtgcag ttgaggcaat actatcaatg aacgcttgtt gagaattagc
    20101 agatgagcga gcataaaaag catagccagt atagttttcg aattcagaca aatctgcttg
    20161 atgggtatgt gtcaatgttt gcccatctgt caattggttc gtgatttctt ctgcattctc
    20221 tggattgttc tgagcttctg ctgatgtact gtcttcggtt tgtgtttgtt ctgttgtttc
    20281 agttgttggt tcttcggttg aaattgtatt ttctgagaca gtagctgact gcaaagtact
    20341 ttctgtatcg ttttcaattc ctgtttctga agaactcgat gtctgagttg cgacagtttc
    20401 tgtcgattct tcagctagca ctgttgtgtt ggcaactgct agatttccta aaagaataac
    20461 gctaaataat aaattctttg ctttcatctt ttttctcctt tgaattatga aacttttcct
    20521 aaataacagt gtaactaaaa aagtaaaagc aagtcaatgt ccatatttaa ataacatttg
    20581 tttcttttta ataaatttgc tttttctgca taaaaagacg taaatgaaga atattcttct
    20641 ccattcacgc cttaaattga tggtcgtttg aataactatt taacaagtaa ttctctctgg
    20701 atattatccg ttatggatta tacttcctgt gtcgtcggac ggataatcat gttgctgaca
    20761 gacatccggt ctggcgtttc tatcgcaaat gctacagcag aagctatatc ttcagatgtt
    20821 aatccccatt ctttttgcgc ttcatgaagt tcaagagcag cctttttgtc gctgatggtt
    20881 tgatataatt cagtttgaac agctcctgga gagatgatcg tagatttgat gttattttgc
    20941 cgttgctctt gacgtaatcc ttccatgatt gcacggacag caaattttgt tccgcaataa
    21001 acggcggaat caggataaac aacatgtccc gccacagaat cagttgaaat gatatgccca
    21061 gatttttgtt tttccatgat tggaagtacg gcggaaattc catttaacac acccatgatg
    21121 ttgatatcaa gcatattttg ccattcatca cggtgacctt caactaatgg agcggttggc
    21181 atgattcctg cattattgta caatacatcg attcgaccga acttttccat cgctaaatcg
    21241 ataactgctt ggacttgtgc aaaatctctt acatctgctg tttgaatata tagctcagct
    21301 tctggtaaag attcttttat tgcttttagg cgatcttctc ggcgtgcagc tataactagt
    21361 ttagcccctt tttctgctaa tagcttcgtt gttgcttcac cgattccgct tgaagcgccc
    21421 atgatgacaa tcactttttc tgataaatca ttcattctat tctcctcctg ttttgaaaaa
    21481 tctcttgctt atactcacta tctcttattt catcttactg ttcaaataat ccgttcgaca
    21541 ggtttgacga ttttggcagg gattcctgca acgatggtat tgtctgggac atctttcgta
    21601 acagttgcat tcgctgcaac aatggcattc tcgccaatcg ttacgcctgg cagaatagtt
    21661 gctcctgctc cgatccaagc atttttcttg atgtggattg gctttactga caagcctctt
    21721 cgttcttttg gatcggttag atggttcacc gtgatgaggt tgacacgagg accaatcaat
    21781 actgaatctt ctaaacagat gccacctaag tcaacgaaca tcacttgacg attgataaag
    21841 acatttttcc ctatactaat atgtttgccg aaatctgtat aaaaaggcag cagaacagtc
    21901 accgtatcat ctactttgtc actaatgata ttttctagcc gtttgcggat atctgctggt
    21961 tcatggtacc cagtattcag cgctgctaaa ggctcttcgt tttccgcttg gatctgatgg
    22021 atcacttcaa agagcggatc cgttactcga atctctttat tgacgatttg tttttcgatg
    22081 aggcttgtca ttttgctccc tccttttatc cttactttat aacggacggc ttatgatgtc
    22141 taatacttat aaaacatact taactattcc ttttaactat acttagtggt atgctttttt
    22201 aaaaacagga gggaaaaaat ggatattcgt atactgacgt attttttagc agtagctaga
    22261 gaaaaaaata tcagccgagc agcaaaatct ctgcatatca cgcaacctac tctctcaaaa
    22321 caactgaaag atttagaaga agaacttggt gtgacacttt tcactcgagg ctcccgagag
    22381 atacagttga cggattctgg tcgatatctt tattcaaaag gaaaagaaat cttgtcgttg
    22441 gtagaaaaaa cggcgaacaa tttaacaaat gacgcaatca tctctggaga aatctacatt
    22501 ggcggaggcg aaactaaagc aatctctttc atttctgata gccttcattc gttgatcaag
    22561 gcgcatcctg atatccagtt tcatttatat agcgggaatg cagatgatat catagacaaa
    22621 ctggatagcg gattacttga ttttggactc gtaatcgaac cgacaaacaa acaaaaatac
    22681 cagtcatttc gactgccagc ccaagatcgt tggggacttt tgatacatcg gaatcatcct
    22741 ttagcaaagc aaacagtcat ccatccgcag gaactgaaaa ctgttccttt gatcatttcc
    22801 cggcaaacgt cagtggacag tcaactagct gaatggctag gtttcagcat agatcagtta
    22861 tcgatcgtcg gaacatataa cttattgtac aatgcttctt tgatggtcga taacgggact
    22921 tttggtgcat tagctctaga tgggatcatc aatacttatg ggacggaaaa agtattcatc
    22981 ccactcgatc cgccattaca agcttcactg aatctcattt ggaaaaaaga ccagcctctt
    23041 tctcctgctg ctcgtaaatt tttagatgtc ctaacggaga aatacagtta agtagagttt
    23101 ttttccttcg ctttcagctt tttaacaacg aataagttaa gcaaaagatc caatgattaa
    23161 ataacataag tttcttaatt tgttccttcc ttttatttct gataattcca gtaaattact
    23221 ataattataa aaaaagaatt gacaaaacat aactgtctat ataaaattga ttacgttaac
    23281 aataattcgt ttcatgtgac tagatcatac taggcatgaa aaatctctga ggaacatggt
    23341 ttccctagga ggtttttcgt gtctattttt gtttggccgc aatcaactgg tctagcaaac
    23401 gtgaaaacca aatcttcaaa aagggtgcgc gcatgaaaat caaaaagatc tttaatcaaa
    23461 atgcagtatt ggtagatgac ggtggacagg aaaaagtagc tattggaaaa gggattggat
    23521 ttgacagaaa aagaaatgat ttgatttttg atcgtgatgt cgaacggata tttgtcatgg
    23581 aaccagaagg tcaaatcaag ttgcaaaatt tacttaatca gattgatgaa cgctttttat
    23641 ttgcagcaga aacgatcatt gatcatgcgg aaactgtttt gatggaaaag ttgaatgaac
    23701 atgtattgat cgctttgacc gaccacattg ctttttctgc ggagaacatt aataacggta
    23761 tcgtcatccg caacaaactt ttaagagaaa tcgaagtgct ttacagtgat gaattcagta
    23821 ttgctcaatg ggcagtagag tatctgacaa aagagcttgg gattccatat acttatgacg
    23881 aagcaggata tatcgcaatc catattcaca gcggacgaag cggtcggaac aataaccatc
    23941 gcagtatccg tgaagtgacg attgtatctg acatcatcca tttagtggaa tcagaattgg
    24001 aaacagatat ccattcagaa ccattttcac tgaattattc aagactggtg aatcatttac
    24061 gactgcttct acaacgaacc catgcgcaac aatatgctgt tttagacacg gaaatcgtag
    24121 aaatggtcaa acgaaaatac ccagaaagct ataagatttc taaaaaaatc cgtgtgttgc
    24181 tgaccaaaga ataccagctc gcgatcacga aagaagaact gggttacttg gccatccata
    24241 tcgagcgttt aagaagcgca atcgtacaaa caaatgttaa caatcatgag gaggaaaaaa
    24301 attgaaagca tatctacaac gaatgggacg ttcccttcaa cttccagttg cggtcttacc
    24361 tgctgctgct ttactagtag ggatcggaaa ctggtgggca tcttatagta acgacattgt
    24421 cgctcatttt ttacaagctg gcggtaacgc agttttaggt caattacctt tgctgtttgc
    24481 cgttgggtta gcactaggga tgtcagtgga caaatcaggt gctgctgcct tggcaggttt
    24541 ggtcgcattt gaagttccag taaatgtttt aaaaactgat tcagtagcta ctttattgaa
    24601 tatcaaacca gaatcagttg atccatcttt tgctcagatc agtaacgtat ttattggtat
    24661 tattgccgga ttgattgcgg cagctcttta taatcgtttc cacgaagcaa aattaccgat
    24721 ggctttatct ttctttagcg gcaagcgtct agtgccaatc ttggctgcct ttgtcatgtt
    24781 gctgatcagt gcagtgctac tgctcgtatg gcctccggtt tactctgctt tagtttcttt
    24841 tgctaaattc attttgagtt taggctgggg tggtgcaggt ctttatggct tcttcaaccg
    24901 tttactgatc cctacaggat tgcatcaagc aatgaactcc gtgttctggt ttgacgtagc
    24961 aggaatcaat gatattggta aatttttggc ttctgaagga acaaaaggcg taacaggaat
    25021 gtatcaagct ggatttttcc caatcatgat gttcgggctt ccagcaggag catatgctat
    25081 ttacagaaat gcacgtccag aaaacaaagc aaaaacagct tccttgatgt tagcagcagc
    25141 ttttgcttca ttctttactg gtgtaacaga accacttgaa ttctcattta tgttcgttgc
    25201 ttggccatta tatgtcttgc atgcaatttt cactgggatt tctttagcag tgagtgcatt
    25261 cttccattgg acagcaggat ttgcctttag tgccggattt gtcgattact tcctatcttt
    25321 gaaaaatccg attgcgaatc agccattgat gttgatcgtc caaggattag taacagcagt
    25381 gatttactac tttggcttta actttgctat caaaaaattc catctgatga ctcctggccg
    25441 cgaggaagca gatctttcag atgacgatac tgcaacgact aattcagaca ataaatatgc
    25501 ggcacaagca agcaaaatct acgctgcatt aggcggagcc gacaatgtaa cttcgatcga
    25561 taactgtact acacgccttc gtttgcaagt caaagataca ggcctgatcg atcaaaataa
    25621 aatcaaagcc actggcgtac ctggtatgaa gatcatcgac ggaaaaaatg cgcaagtcat
    25681 cgtaggtaca gaagtacaat tcgttgcaga tgagatggca aaactacatg gtggtgctgc
    25741 aacacgacct gcacaaacaa acaccgtggt taaaacagaa acatttgccg gtggaacgat
    25801 cgaacaagat atttacgcta tcgcaaatgg gaaactgatt ccaatcactg aagtttcaga
    25861 tgatgtattc gcggaaaaaa tgatgggtga cggctatgct gtattaccag aaaatggaga
    25921 aatcttctct ccaatcgctg gtacgatcac aaacattttc ccaacgaaac atgctgtcgg
    25981 aatccaaaca gatgctggta tcgaagtctt gcttcatatg ggcatcaaca ctgttgactt
    26041 aaaaggcgaa ccattcactt tatatgtaaa agaaggtcaa aaagtcgcaa gaggtcaatt
    26101 gattgcttta gttgatcttg ccgctattca atctgcaggc aaaaacacgg atatggtcgt
    26161 tgtattcaca aatggcgaca aagtccaaag cttagaaatc gaacccgcac gtgatgtaaa
    26221 agcaaatgat aaaatcggct ctgtttccaa caaagcctga gccatcgtct tccccagact
    26281 tttttatcga taaacaaaca ggagctgaga caaaaatctt gtctcagctc ctttttccga
    26341 ataaaaacgg cgttctcctg ccaactccgc ggtaataagt ccagccaaac gtaacatatg
    26401 aagagctatt ttttatttga ctcttcttat tacttgatgc agaacagctt ttttacaacc
    26461 tctgataaac ggtgttcaaa aaccagttta tcggtatgaa gtcaaattta tgcaaaaatg
    26521 tggaaagcca ttttcacaaa atttttcttc atactcaaaa ctaatcggct ttttcacaac
    26581 ctctttatac attattcctg atccaatatt tcttttaatg ctgcttcaag agaagttaat
    26641 ggttttccca atactttttc taaatcatca gaggaaatag ctaactgatc ctttttaata
    26701 tcatgttgga tcgctaaaaa catgtcagct gcttcttgag ggaatccggc ttcttttaga
    26761 ttttcgacaa acgctgcatc acttgcttca ataatttcta actttttacc tgtcgcacgc
    26821 tctaatgcct tggctaattc ttcatagtca gttagattgc cggataattc taagatttct
    26881 ggagagtcac tttctactag tacttttgct gcagcttctg catattcacg tttcaatgcc
    26941 caacctgttt ttccatttcc tgcagcataa acgaattgac cagtttttaa agcctgccca
    27001 atgataggta attcattctc tacataccaa ttattccgta aaaatgtatg ggaaatacct
    27061 gaatccttaa tcattttttc agtgaattgg tgatctggcg ctaatacact gatcgagtga
    27121 tcggcatctg caaaacttgt ataagcgata taagataccc cagctgcttg tgctgccttc
    27181 actacattct tatgttcggc ttgacgattt cctggaacgc cagagacaaa aagcaatcga
    27241 tctattcctt tcaacgcttc tttcattgag tctaaatcat cataatcacc aatacgtata
    27301 ttaaatccag cttctttcag tgcttctcct ttttcttcac tacgtactag tacatagatt
    27361 tcattttgtg gaaccatctt ttttaagaat tccagcgcat aaccaccaaa acctccagtt
    27421 gctcctgtta ctaaataatg catatttgcc actccctatt ctttttattt gttaagattt
    27481 acagctgtac atttataaat tacaccttta tcataaagag tgtggtaaga taagtcaagc
    27541 aaaaaaaatg aaaggatgac aactgatgaa gtattctctg caatttagtg atgcaatcca
    27601 tgtacttgcc tatattgaaa tgtttcaaga tacccgatca ctttctagtg agatgattgc
    27661 cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc atgagtcagc tcaaaaaatc
    27721 cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc cttgccaaaa gtccagatca
    27781 gatttcttta ctagatgtct atcgcagcat cgaaggtaat acacagctta tccaagtcga
    27841 tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc caagaagctt tagaagaaag
    27901 ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct aagatcacac ttgatagtct
    27961 gatacataaa atagccgttt tggaaaaaga aaaaagacca gaaaacacag gcctcgtaga
    28021 gagattttta taattctctc tactgtgcct gcatttttct gatcggaatc gtctacataa
    28081 attcttttat tctccggggg acaaaagcct tgtcatgccc ctttttcctc tctaatgctc
    28141 aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg ttcaagtagc tgaccctcgg
    28201 cattagttct gaaaaatgca aaatatggaa agctatttcc catttttcct ctctaatgct
    28261 caggtcaaag cgctactttc acgacctcta tattatcatg gtttattgac taccggtatc
    28321 cagatttctc ccatatattt cccgttggta actcccattt cgactacagc atttggaccc
    28381 ccaacatagg cgtaatcttc tacttctctt aaaacatgcc caaaggccgt attcgtcaaa
    28441 tcatttctta attcttcagg cgattctgct aaagcgatta caacaagata cgttcctttt
    28501 gggaatggga tgattcgggt agtgtttgga acatcctgac tcgtttgaac accgacatag
    28561 tacatcattt tcccgttata gggttcgttg actgtaaaga aataatgatt ttcagcagct
    28621 tgtttcaatg catctattgt tccattaccg ataacttttt gctcaaatgc ttgtttctct
    28681 gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt ccacaccaat acccgtcacc
    28741 gtaaaatctg gtttttcttc gatcctatac tttgccattt ctcccaccct ttctattata
    28801 ttaagttcat cttacataaa attaaaggga aatgacacga ttacgctctt ttttctaggg
    28861 atatttttat tttttaacta tttttttgct ttcactgcaa tccaaatctc actgtaaaca
    28921 ttactgaaat cctctcccca ttttgtaaaa gagatctcgg gagcttcgac taactcataa
    28981 tctgaagaag gaagccattc tgcatagatt ttcccccaag tatcttgtaa agtttgggga
    29041 aatggccctt tattaggaaa aatggcccaa gtgtgttctt ctatagcaag catttctaaa
    29101 tcagcgtacg gattttcttt tgtcgtagca aagccaatca tgtgcatcaa actgcccttt
    29161 tcttccaagc gggctccatc aaatccataa gaaacgttga ttacttgatt tggatataaa
    29221 tctcctaact tatgcatctc ttccctttga gtctccgtga tcgtctgcgc taacttttgt
    29281 atttcttgat tgactccttc aaatttgaca ggaacttttt tcgccacacc tgccacataa
    29341 aactgttctt tcttttcgat acgaaattcc atcgattttc ctcctctgac atcaataaaa
    29401 aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc tgatttctga aggcagatat
    29461 cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg tttcatatcc atatctaaac
    29521 gccgtttctg tcactcttga tccatctagg agatcgcgat tagccaaagc caatctacgg
    29581 tttttgatat agtccattag cgacatccct gcaataaacg taaagatgcg ttttaattga
    29641 tattcagaga ttcctgtatt ttcggctatt attttatagg aaagtccttc tgtcaaatgt
    29701 tcttcgatgt aatcgatcaa ttggttcaga tctttaagca tatttatctt cctccttgct
    29761 tgccttttta tcatattatc aaagaaagtc aattacttga tgaatcagga accaatttag
    29821 tcagatgtag aaaatgttgt atggatctaa agaaaattct caagcagcgt ttcgtaacgg
    29881 ataattggta ttatctgcct atctatgttt tacctttaga aaaataaatt ttggggaaga
    29941 cacattctaa gtaaacaaag cggtaaaaat atcttttatt cccttagtta atccgcttac
    30001 tacctactgt acaaagcaaa ttgttgttca aactgctgat cagaacgctg cttggatttt
    30061 tctttgcgat acatcatacc tcttttatca attggaacaa ttatttattt ctaacaaaat
    30121 cacttcattt ttgtcagata aataaaaaac aaaaaaagtt ccatctttaa aacacgctat
    30181 tcttttactt tttctcacat tctctaagaa aagaaaagga gaa
//
LOCUS       DAZAOD010000020        29986 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000020 DAZAOD010000000
VERSION     DAZAOD010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.021"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            147..1016
                     /locus_tag="ACHDPO_001002"
     CDS             147..1016
                     /locus_tag="ACHDPO_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFN3368646.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="ACHDPO_001003"
     CDS             1225..2250
                     /locus_tag="ACHDPO_001003"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFN3368647.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="ACHDPO_001004"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="ACHDPO_001004"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFN3368648.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3333..5036
                     /locus_tag="ACHDPO_001005"
     CDS             3333..5036
                     /locus_tag="ACHDPO_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFN3368649.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="ACHDPO_001006"
     CDS             5038..7071
                     /locus_tag="ACHDPO_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFN3368650.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="ACHDPO_001007"
     CDS             7082..7522
                     /locus_tag="ACHDPO_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3368651.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="ACHDPO_001008"
     CDS             complement(7722..8849)
                     /locus_tag="ACHDPO_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368652.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="ACHDPO_001009"
     CDS             complement(8852..9529)
                     /locus_tag="ACHDPO_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFN3368653.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="ACHDPO_001010"
     CDS             9793..11559
                     /locus_tag="ACHDPO_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFN3368654.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="ACHDPO_001011"
     CDS             11574..12011
                     /locus_tag="ACHDPO_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3368655.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="ACHDPO_001012"
     CDS             12024..13175
                     /locus_tag="ACHDPO_001012"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFN3368656.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13237..13935)
                     /locus_tag="ACHDPO_001013"
     CDS             complement(13237..13935)
                     /locus_tag="ACHDPO_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFN3368657.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13928..15280)
                     /locus_tag="ACHDPO_001014"
     CDS             complement(13928..15280)
                     /locus_tag="ACHDPO_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFN3368658.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15503..16903)
                     /locus_tag="ACHDPO_001015"
     CDS             complement(15503..16903)
                     /locus_tag="ACHDPO_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFN3368659.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17064..17801
                     /locus_tag="ACHDPO_001016"
     CDS             17064..17801
                     /locus_tag="ACHDPO_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFN3368660.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17926..18405
                     /locus_tag="ACHDPO_001017"
     CDS             17926..18405
                     /locus_tag="ACHDPO_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFN3368661.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18402..19169
                     /locus_tag="ACHDPO_001018"
     CDS             18402..19169
                     /locus_tag="ACHDPO_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFN3368662.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19399..19968
                     /gene="lepB"
                     /locus_tag="ACHDPO_001019"
     CDS             19399..19968
                     /gene="lepB"
                     /locus_tag="ACHDPO_001019"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFN3368663.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20072..20674)
                     /locus_tag="ACHDPO_001020"
     CDS             complement(20072..20674)
                     /locus_tag="ACHDPO_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFN3368664.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20780..21010
                     /locus_tag="ACHDPO_001021"
     CDS             20780..21010
                     /locus_tag="ACHDPO_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368665.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            21001..21249
                     /locus_tag="ACHDPO_001022"
     CDS             21001..21249
                     /locus_tag="ACHDPO_001022"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368666.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            21355..21939
                     /locus_tag="ACHDPO_001023"
     CDS             21355..21939
                     /locus_tag="ACHDPO_001023"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFN3368667.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21942..23015
                     /gene="prfA"
                     /locus_tag="ACHDPO_001024"
     CDS             21942..23015
                     /gene="prfA"
                     /locus_tag="ACHDPO_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFN3368668.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23008..23847
                     /gene="prmC"
                     /locus_tag="ACHDPO_001025"
     CDS             23008..23847
                     /gene="prmC"
                     /locus_tag="ACHDPO_001025"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFN3368669.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23840..24019
                     /locus_tag="ACHDPO_001026"
     CDS             23840..24019
                     /locus_tag="ACHDPO_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368670.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24041..25066
                     /locus_tag="ACHDPO_001027"
     CDS             24041..25066
                     /locus_tag="ACHDPO_001027"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFN3368671.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25257..26501
                     /gene="glyA"
                     /locus_tag="ACHDPO_001028"
     CDS             25257..26501
                     /gene="glyA"
                     /locus_tag="ACHDPO_001028"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFN3368672.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26654..27601
                     /locus_tag="ACHDPO_001029"
     CDS             26654..27601
                     /locus_tag="ACHDPO_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFN3368673.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27735..28364
                     /gene="upp"
                     /locus_tag="ACHDPO_001030"
     CDS             27735..28364
                     /gene="upp"
                     /locus_tag="ACHDPO_001030"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFN3368674.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28503..28745)
                     /locus_tag="ACHDPO_001031"
     CDS             complement(28503..28745)
                     /locus_tag="ACHDPO_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368675.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28866..28938
                     /locus_tag="ACHDPO_001032"
     tRNA            28866..28938
                     /locus_tag="ACHDPO_001032"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28899..28901,aa:Thr,seq:cgt)
     gene            complement(29057..29695)
                     /locus_tag="ACHDPO_001033"
     CDS             complement(29057..29695)
                     /locus_tag="ACHDPO_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFN3368676.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29818..>29986)
                     /locus_tag="ACHDPO_001034"
     CDS             complement(29818..>29986)
                     /locus_tag="ACHDPO_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFN3368677.1"
                     /translation="DLENASFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALG
                     FARKFLQIKVV"
BASE COUNT        10208 a         5276 c         6086 g         8416 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gtctgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt ctggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccatgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaacgtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg acgaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcggaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggcag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatcca gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaagag
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttcgct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata
    13261 gggcagatcc aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc
    13321 caggttctca tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta
    13381 aatgacacct tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa
    13441 aggtcgttca ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt
    13501 ttcattgaat tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact
    13561 taacgtgtag tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta
    13621 gtagtgacct agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat
    13681 atagttgatc aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa
    13741 gtcttgacca ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat
    13801 actaacgatc tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa
    13861 aaggtttccg ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag
    13921 ttcataatta gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac
    13981 gaagctgcaa tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt
    14041 tgattttttc gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc
    14101 cggcaacttt tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg
    14161 ggatatccat atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc
    14221 cgtctgcgta attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa
    14281 tcatatcgat tacttgattg atacctacag gatttttgac aagtactaat gtacattttt
    14341 tcccattgat attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt
    14401 gtttgatttt atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat
    14461 tgtagacatt atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat
    14521 ctgctgacac attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt
    14581 tgaagtcaca atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat
    14641 gcaagatgtg atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt
    14701 cacgatcttc ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat
    14761 tgaagattgg tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt
    14821 ctacaatcat tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa
    14881 tatttgtaaa taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt
    14941 catctatttc taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag
    15001 tcgatacaat tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt
    15061 gctggcgcaa aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga
    15121 caacgacgac ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg
    15181 ctagtttacc tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg
    15241 tttttccaac tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga
    15301 tttgctgacg aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt
    15361 ttcttattct taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga
    15421 tttaacaaaa aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt
    15481 ccctcttacc tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc
    15541 ctagatctcg tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc
    15601 caataaacat cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc
    15661 ctaaagataa accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg
    15721 tttgttcttc tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca
    15781 taaagacaac gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga
    15841 tgttatcttc acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg
    15901 ttcgaatccc gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa
    15961 tgatcagtgt tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag
    16021 tcgtaatcga ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata
    16081 aatggtcctt ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag
    16141 ctaacacagc taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt
    16201 tgtataatag ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa
    16261 tcaaaaacat gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc
    16321 cagtgacgtc aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa
    16381 cggcatcacg ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc
    16441 caaaaagtaa ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac
    16501 cagacaaacg cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc
    16561 gtcgtttaga aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt
    16621 gaaataatat ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag
    16681 tcgatagtcc agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa
    16741 catggctatc tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca
    16801 tcaatatata ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct
    16861 gtcctcgccg ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac
    16921 aatagtcgtt tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca
    16981 gataacaata cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa
    17041 aaagaaggag gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa
    17101 atcaaaaaat aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag
    17161 aagtaaagcc taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg
    17221 aattcatgtc tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta
    17281 aaagtgagta tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga
    17341 aaactgacca tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa
    17401 tggttttaac aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct
    17461 tcaatatgcg attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg
    17521 gaagtgccct gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg
    17581 atatccaaaa gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct
    17641 atgaacgctc tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt
    17701 gcgtgttcgc tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag
    17761 cttacttaaa aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac
    17821 gtaagaaaaa aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag
    17881 taaagtaagg aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca
    17941 cctattttga agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt
    18001 attgtgaata gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca
    18061 acaccaacta cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc
    18121 actacgacaa gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca
    18181 actgacagct caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc
    18241 aatccaagta caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact
    18301 gtagatgata acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca
    18361 ggaaataccc aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc
    18421 ttatcaacgg ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc
    18481 gtggatatac gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac
    18541 tttggcaaaa ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg
    18601 tttattttac tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg
    18661 tcactcagct ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat
    18721 cgatagataa tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg
    18781 acgaagatta tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga
    18841 tcaaaacaaa tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc
    18901 cttattacta tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct
    18961 actcggacat ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac
    19021 ctgtcggatt gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc
    19081 cttatcgtct gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata
    19141 gtcgtagcca aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg
    19201 ataaaaacgt ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt
    19261 atataacgag aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt
    19321 gtagaataaa gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat
    19381 acaagtagga ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta
    19441 ttagcggcta ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat
    19501 tcgatggacc ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat
    19561 gaacgaatgg atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa
    19621 cggatcatcg gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat
    19681 ggcaaaaagt atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag
    19741 ttacaaggag aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc
    19801 tttacgagtg actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac
    19861 cgcttgattt caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga
    19921 aaagttgttt tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa
    19981 aagaagctgt gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct
    20041 tggagttgct cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa
    20101 gcgaagcgtt tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag
    20161 agacaaagcc cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga
    20221 ctttcggatg actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag
    20281 gagctaaaat ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta
    20341 caagtgatag aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt
    20401 ggatcgttcg gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca
    20461 tagtttctga agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa
    20521 caagcccagt tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat
    20581 aagtagttag ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat
    20641 ggttagcgat ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg
    20701 aaattttaac ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa
    20761 gggagaatct agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa
    20821 gtgtgtccga gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga
    20881 aaaatatatc gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata
    20941 tttaggcttt atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt
    21001 atgggaataa aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca
    21061 gaaggttacg cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac
    21121 tactctatat atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa
    21181 gtttttccaa atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa
    21241 caaaagtgag caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa
    21301 atgctgaaaa tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca
    21361 caactatttt ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc
    21421 gcacataatt atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca
    21481 agagatggtt taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata
    21541 tttgaagaaa cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg
    21601 ctgatcgatg aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg
    21661 gacgaattgg atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta
    21721 tttgaaggat caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc
    21781 tgttggttct gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt
    21841 tatgaaggcg atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa
    21901 cattactttc acccatcaat gattacagaa ggagaataag catgtacgat caattacaag
    21961 caattgaaga ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg
    22021 atacaaagcg ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag
    22081 tttatcgtcg ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg
    22141 aaaaactgga tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag
    22201 aaaaagaagt cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg
    22261 ataaaaatat catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg
    22321 ctggcgatct tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag
    22381 tgatggaagc taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg
    22441 gagacaacgt atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc
    22501 cttcaactga atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag
    22561 aagctgaaga agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg
    22621 cttcaggtgc tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact
    22681 taccaacagg gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa
    22741 aagcaatgaa aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg
    22801 agtatgatgc caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga
    22861 cgtataattt cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat
    22921 tagatcagat tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc
    22981 aaacatcaaa actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca
    23041 cgggcttctt cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt
    23101 ttggaacgaa aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca
    23161 gaagaagaac agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct
    23221 cagtatttgc taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca
    23281 ctgatccctc gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt
    23341 gtaccgttag aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa
    23401 gcagcaagaa aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta
    23461 gcgaaagaaa atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta
    23521 ggaccagtaa tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg
    23581 aatgaatggg aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt
    23641 gctgagaacg atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta
    23701 aaatcaaatg gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa
    23761 atatttcagc aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat
    23821 gaacgaatga tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt
    23881 tattataaaa aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt
    23941 ttatccacta ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag
    24001 acaaaataag aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga
    24061 tgaaacagaa ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc
    24121 taccgaaaca gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt
    24181 gttttctgta aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga
    24241 acaagtaaaa gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt
    24301 ctggcctgga ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt
    24361 gacgggagga ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt
    24421 aatcgaactt tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag
    24481 tccaacgact gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga
    24541 tgatggagct acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc
    24601 catgcctatg attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga
    24661 atctcctgtt gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg
    24721 gatgaaatac aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg
    24781 gtcaactgca gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc
    24841 cgaaattgcg gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc
    24901 agtagaagcg gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact
    24961 tggattagat ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat
    25021 gaatcgcttg aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg
    25081 tcgcattctt ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa
    25141 ctaagcgtaa ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg
    25201 aaaaataaaa ttgtaggaaa ataaaattgt aggaaaataa aaaggagctg ttgtttgtgg
    25261 tagattacaa aacgtttgac cctgatcttt gggctgcgat cgccaaagaa gaagaaagac
    25321 aagaacataa tttggagctg attgcctctg aaaactttgt ctccgaagca gtgatggctg
    25381 cacaaggaag tatcttgaca aataaatacg cagaaggtta tccagggcat cgctattatg
    25441 gtgggtgtga atttgtcgat atcgttgaaa atttagcgat tgaccgtgca aaagaattat
    25501 tcggagcgaa atttgcgaac gtccagcctc actccggctc tcaagccaac acggctgctt
    25561 atctcgcttt ggtagaacca ggggacacga tcttaggaat ggatctttcc gcaggcggac
    25621 atctaacaca tggatcacca gtcaacttca gtggcaaaac ctatcacttt gttgcttacg
    25681 gtgttgatcc gacaacagaa gttattgatt ataatgtggt acgtatttta gctagaaaac
    25741 atcaaccaaa attgatcgta gcaggtgcca gtgcttacgg acgaacgatc gactttgcga
    25801 aattcagaga aatcgcagat gaagtaggcg caaaactgat ggtagatatg gcacatatcg
    25861 caggattagt agcagcagga cttcatccta atccagttcc ttatgcagat atcacaacga
    25921 ctaccactca taaaacattg cgtggccctc gaggcggcat gattttgaca aacgatgaag
    25981 cattagcaaa aaaaataaat agtgcggtat ttcctggtat tcaaggcggc cctctagagc
    26041 atgtgattgc gggtaaagca gtagcattca aagaagcatt agatcctgca tttaaagaat
    26101 atagtgaaca aatcatcgcc aatgcaaaag caatggtcaa agttttcaat caagcaattg
    26161 gaaccagagt catttcaggg gcgacagata atcatctgat gttgatcgat gttcgcgagt
    26221 taggtataaa tggaaaagaa gcagagagca ttttggacag tgtgaatatc actgtaaata
    26281 aaaactcgat tccttttgaa acactaagtc cattcaaaac aagcggtatt cgaatcggca
    26341 cgccagcaat cactactcgc gggttcaaag aagaagatgc tgtaaaagtg gctgaactag
    26401 ttgtcaaagc attacaagca aaagatgata acgctcaact agacgaagtc aaaacaggtg
    26461 tacgcgaatt aactgaaaaa tttccgttgc ataaaaaata aaaatttaaa ttccattagt
    26521 aaacagaaaa gttcaatgtt gggcttttct gtttattttt tgggaaaacg gattctttga
    26581 caatatcggt gatgctctct agtatatgag gtgtaatttt agtcttcaca ctaaatctca
    26641 gggaggaaaa gtcatgactg atcgtatctc gttagaaaag gaagcagtag cattcagtga
    26701 tgcaaatgcg cctcatccgc gtatctatga actagcaccg gaagaaggaa gagttttact
    26761 agaagaagta caagaatcac ctgtgaacaa atattccgtc gatattgaag acttgatggt
    26821 ggatactggc gaatggggaa aactcaatat tcgtctcgta cgaccagaag ggaatatgga
    26881 taaattacca gttatttttt atattcatgg agcaggctgg gtttttggca gtgctcaaac
    26941 ccatgataaa ttgatcagag aacttgcggt tcgtacgaat tccgtcgttg tctttccaga
    27001 atatagtcga tcaccagaag caaaatatcc aacagcaatt gaacaaaatt atgctgtgtt
    27061 gcaacagctg aataaattag ccaagtcaaa aaatctggat ctcgagaatc taatcgttgc
    27121 aggagattca gtaggtggta acatggctac agtcatgacg atcttaacaa aagaacgaaa
    27181 gggcctccca atatccaagc aattgctgta ttatccagtc acaaacgctg attttgatac
    27241 agattcctat catgaattcg gagaaaacta ttttttgaca agagaaggaa tgatgtggtt
    27301 ttgggaccaa tatacgacga atgaagaaga gcgtgctgaa atcacagctt cgcctttgag
    27361 agcaaatata aatgaactaa atgatcttcc ttcagcaatg attttaacgg gagaagcgga
    27421 tgtattaaga gatgaaggtg aggcttatgc gcgcaaactt cgtgatgcag gggttcctgt
    27481 tacacaagta cgcttccaag gaatcatcca tgattttgtc atggtaaatg ctatggatca
    27541 gacaaaggca acgcgtgcag caatggcatt atctacttct tggatcaaga aaaaagaata
    27601 agctttgctt gtccgcagga aaacttcttt tcaaaaacgg attttcttag gaaaaatggc
    27661 gagtttgact agtcaatcac ttgattttgt tttacaatta aaaagaaacg acagaacaaa
    27721 ggagagctta aaaaatgggc aaatttcaag tgatcgatca tccattgatt caacacaaac
    27781 taactattat tcgggacaaa aactgcggaa caaaggtttt tcgtgaagta gtcgatgaaa
    27841 tcgctatgtt gatggcatat gaagtatcac gggatatgcc attggaagac atcgtgatcg
    27901 aaacaccgat cactgaaaca acacaaaaaa cgttgtctgg taaaaaagta gcgattattc
    27961 caatcttgcg cgcaggtatt ggaatggttg acggtatctt ggaattgatt ccagctgcta
    28021 aagtgggaca tatcggtctt tatcgagatg aagaaacatt ggaaccacat gaatatttcg
    28081 tcaaacttcc agaagacatt gatgcacgtc agttgtttgt agtagatcca atgttggcaa
    28141 caggcggatc agcaatcatg gcaatcgatg cattgaaaga acgtggcgcg tcgaacatta
    28201 aatttgtttg tttggtagca gcacctgagg gagtaaaagc tttgcaagaa gcgcatcctg
    28261 atattgacat ctatacagct tctctagatg aaaaattgaa tgaacatggt tatatcgttc
    28321 ctggactagg ggatgcgggt gaccgtttgt ttggtacaaa ataagtaaat acgaaaaagg
    28381 gtgtgacaca acttttgtca catccttttt tggtcatttt taacgtttga tgcagaacag
    28441 ctttttcaca gctttcgttt gcatataaaa aaaccatccc aaaaatgcag agatggtcaa
    28501 attcaaatct tttttagttc tttgtagtta acgattacta cacccttact ttgcgtcatc
    28561 aagttcgcat tttctgcagt ttcatcaatc tcaacaacag cggaattttt caattgcttt
    28621 gaaatcgttc cagtttgcga cttgccgtga attgtgaaca ttacgtgagt attgatcttg
    28681 aatttttcac caatttccga tggtacgata gttgtatcaa attttccaaa agttgccatt
    28741 ttcataaaac ctgcctttca catcaattat accacgtttt atgaaaaata tcatgaaatt
    28801 aaactaattt tccatcggac tctttacaat cagccaaata gagtatataa tttcttttgg
    28861 ataaggccag cttagctcag ttggtagagc aacgcactcg taacgcgtag gtcgtaggtt
    28921 cgatccctat agctggcatt aaaagagaag acagatatat caaggatttt taatccattg
    28981 atacatctgt ctttttgttt aaaggaaata aagtatgctt tcttagcaat agagcatgta
    29041 ttatttctat aaaaatttag gagaataaaa cgactagcaa tatagctgtg aaatcaaata
    29101 tcacatgaac tgcccaactt gtaatgatcg agttgctttt aatggcagct tggttgaata
    29161 acaatcttgc caccccttgt atcaaaagga tgtgtgctac agtgtgtaaa atatttccat
    29221 tatcataagt actgtaatgg ataaatccaa agatgattgc tgacaagaaa ctagcgacag
    29281 gaatgctgaa cttactagaa aaaatagcga gaaaatacac tgagaacaat tcttctccaa
    29341 gtatcatgat aggcaaaata ataaataata acgggctgaa agcctcattt attggattgc
    29401 ctgttaaacc ccatttcaaa atttgttgca aaaataccga gactgcggca ctgattacta
    29461 cattgataaa aaaatatttg gctatatttt tgacaggagc gacaggtttc gagaacattt
    29521 ttttcgtatc ttttttacca aaaacaagtg taaatgctat aaatccagtg atagttaaag
    29581 aaaaaatgct aataatggat ggcgcaaata gcaaccctaa caaaccgagt acaacgacaa
    29641 tagtgcccaa tatccctttt ttaagttcta ttttttttcc taaaatgtta ttcatgataa
    29701 taactcctac tattcagttt ttgaagatag agtcagtata catgaagagt taaaataggc
    29761 aatgtttttt tatggatatt tgtattgcta aaaatttatc ttatatattc attttgatta
    29821 tactactttt atttgtaaaa attttctagc aaaaccaagt gcttgcaact gattaagcgt
    29881 acaatttttt agatgttccg agcgtacttc aatcatttca aaggagttgc tacttaaatc
    29941 gatatttttt aaatcagtat caaaaaagct agcattttct aaatca
//
LOCUS       DAZAOD010000021        29794 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000021 DAZAOD010000000
VERSION     DAZAOD010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.022"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(158..898)
                     /locus_tag="ACHDPO_001035"
     CDS             complement(158..898)
                     /locus_tag="ACHDPO_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368678.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(1028..1975)
                     /locus_tag="ACHDPO_001036"
     CDS             complement(1028..1975)
                     /locus_tag="ACHDPO_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3368679.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(2104..2868)
                     /locus_tag="ACHDPO_001037"
     CDS             complement(2104..2868)
                     /locus_tag="ACHDPO_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFN3368680.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
     gene            complement(2872..3261)
                     /locus_tag="ACHDPO_001038"
     CDS             complement(2872..3261)
                     /locus_tag="ACHDPO_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368681.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            3396..3938
                     /locus_tag="ACHDPO_001039"
     CDS             3396..3938
                     /locus_tag="ACHDPO_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFN3368682.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            4086..4718
                     /locus_tag="ACHDPO_001040"
     CDS             4086..4718
                     /locus_tag="ACHDPO_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368683.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(4852..4977)
                     /locus_tag="ACHDPO_001041"
     CDS             complement(4852..4977)
                     /locus_tag="ACHDPO_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFN3368684.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(5111..6004)
                     /locus_tag="ACHDPO_001042"
     CDS             complement(5111..6004)
                     /locus_tag="ACHDPO_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFN3368685.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(6186..7112)
                     /locus_tag="ACHDPO_001043"
     CDS             complement(6186..7112)
                     /locus_tag="ACHDPO_001043"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFN3368686.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(7197..7958)
                     /gene="pflA"
                     /locus_tag="ACHDPO_001044"
     CDS             complement(7197..7958)
                     /gene="pflA"
                     /locus_tag="ACHDPO_001044"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFN3368687.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(8202..10433)
                     /gene="pflB"
                     /locus_tag="ACHDPO_001045"
     CDS             complement(8202..10433)
                     /gene="pflB"
                     /locus_tag="ACHDPO_001045"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFN3368688.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(10710..13160)
                     /gene="parC"
                     /locus_tag="ACHDPO_001046"
     CDS             complement(10710..13160)
                     /gene="parC"
                     /locus_tag="ACHDPO_001046"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFN3368689.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(13172..15217)
                     /gene="parE"
                     /locus_tag="ACHDPO_001047"
     CDS             complement(13172..15217)
                     /gene="parE"
                     /locus_tag="ACHDPO_001047"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFN3368690.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(15383..15817)
                     /locus_tag="ACHDPO_001048"
     CDS             complement(15383..15817)
                     /locus_tag="ACHDPO_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFN3368691.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            15944..16582
                     /gene="plsY"
                     /locus_tag="ACHDPO_001049"
     CDS             15944..16582
                     /gene="plsY"
                     /locus_tag="ACHDPO_001049"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFN3368692.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(16714..17589)
                     /locus_tag="ACHDPO_001050"
     CDS             complement(16714..17589)
                     /locus_tag="ACHDPO_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFN3368693.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(17671..18462)
                     /gene="codY"
                     /locus_tag="ACHDPO_001051"
     CDS             complement(17671..18462)
                     /gene="codY"
                     /locus_tag="ACHDPO_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFN3368694.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(18480..19880)
                     /gene="hslU"
                     /locus_tag="ACHDPO_001052"
     CDS             complement(18480..19880)
                     /gene="hslU"
                     /locus_tag="ACHDPO_001052"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFN3368695.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(19894..20442)
                     /gene="hslV"
                     /locus_tag="ACHDPO_001053"
     CDS             complement(19894..20442)
                     /gene="hslV"
                     /locus_tag="ACHDPO_001053"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFN3368696.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(20479..21384)
                     /gene="xerC"
                     /locus_tag="ACHDPO_001054"
     CDS             complement(20479..21384)
                     /gene="xerC"
                     /locus_tag="ACHDPO_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFN3368697.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(21582..22958)
                     /gene="trmFO"
                     /locus_tag="ACHDPO_001055"
     CDS             complement(21582..22958)
                     /gene="trmFO"
                     /locus_tag="ACHDPO_001055"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFN3368698.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(22927..25005)
                     /gene="topA"
                     /locus_tag="ACHDPO_001056"
     CDS             complement(22927..25005)
                     /gene="topA"
                     /locus_tag="ACHDPO_001056"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFN3368699.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(25127..25984)
                     /gene="dprA"
                     /locus_tag="ACHDPO_001057"
     CDS             complement(25127..25984)
                     /gene="dprA"
                     /locus_tag="ACHDPO_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFN3368700.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(26040..26807)
                     /locus_tag="ACHDPO_001058"
     CDS             complement(26040..26807)
                     /locus_tag="ACHDPO_001058"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFN3368701.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(26800..27660)
                     /gene="ylqF"
                     /locus_tag="ACHDPO_001059"
     CDS             complement(26800..27660)
                     /gene="ylqF"
                     /locus_tag="ACHDPO_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFN3368702.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            27920..28318
                     /locus_tag="ACHDPO_001060"
     CDS             27920..28318
                     /locus_tag="ACHDPO_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFN3368703.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            28555..29097
                     /locus_tag="ACHDPO_001061"
     CDS             28555..29097
                     /locus_tag="ACHDPO_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFN3368704.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(29180..29731)
                     /gene="lepB"
                     /locus_tag="ACHDPO_001062"
     CDS             complement(29180..29731)
                     /gene="lepB"
                     /locus_tag="ACHDPO_001062"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFN3368705.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
BASE COUNT         7996 a         6270 c         5105 g        10423 t
ORIGIN      
        1 ttattttgcc attattttct tacttactgg gagaaaaaat tcgcttaaac tcaaaaaaat
       61 ttgaggatac gatataaact ttcggataga gtataaaata aggaaacgcc gcagcgtttc
      121 ctttccaact gtagccgaat ataaatttgt atatcactta tttaaaatag ctattttctc
      181 ccaaagagtt tccttgatca tcgatcaatc cttgtaatga gcgttctaag ataccatggc
      241 tttttttcga ttttttttct tctgactgct ttgtttcctc taacgttttt gttcgattga
      301 atgttcgtac agacggctca ccatttcttt tttcttgata cggcgtcggt tctgtatcga
      361 acaacagata agagtcatcc gtttttttca tcgattcgat taaatgatcc tcagaaattt
      421 tgctttctct agggtctggg ataatcgatg cgggtacata tttaggaaca aaataagaac
      481 gctcccgcac cttcgtgtca acagatgcgt ttcgtgtagt atgcttggac tctgtccttg
      541 tttcactttg tctgacagaa cgagaggaat caccaaaaag tttttttcgt cctgtcgatg
      601 tgatttctga ttggtaatgg ccggtataat ccggtaattt tcctttatgc ttttccaaat
      661 tttccttacg cggagctgac ttcaatccat ttgttgcacg acgcttgcga cggattttct
      721 cggtgttcgt gttcgtgaaa tgaaattctt tcatctgttc aaacggggac tgattctgtt
      781 cagtcaaaag atcttcttgt ccgtcaaata atactcgctt cttgtcgttg gttaatttta
      841 cgcctaactc atcatcgtac gcaggaaaac ggaaatgttt tcgtctgatt tctttcattc
      901 aaaccatcct tctcaaaaat ggaacttttc tcaataatag cacagattca ttgttttcag
      961 tagcaatgcg ctgattattt taagaaaata gcgatgaatt tcataaatat atatatagta
     1021 ataagactta attcgttgtc tctctgataa ctagttcagg aaaaaaacga cgataacctt
     1081 gactcgcccc tttttcttct atttttttta acaacatttc tccacatact tcacccatac
     1141 gtataatatc ttgcttgatc gttgtcaatt taggtgaact gatttggtct aaaaataccc
     1201 catcaaatcc aatcacacca aattcttcgg gcaagtgtcc tccagcattt ataatccctc
     1261 ttactgctcc tagtgctagc cgatctgaac tacatacaaa acaagtttta tctgtaaaat
     1321 ctgcccagtt ttctgtcata tatctttcta cttctgtcga atgatttgga aaccgcaaga
     1381 ttttactagg aagatcaact tccttcatca cagataaata accagtttcc cttgaaattt
     1441 caaaaggctc gtccacttcg ataccgatat aaataatcgt ttgataatct ctttctaagg
     1501 catattgcgt tgcttttgct gtaccatatt cattatcgct gtctacataa tcatatcctt
     1561 cagaattttc cccaaacaag acaactggtt tttccaaacg gtcgatccaa tcgaagtctt
     1621 tttttctgac acctgtgatg atgtatccat cacaagaacc gacgtcgaag gcatcatttg
     1681 taactaattg gagagaataa tgcgctttac cgatccgttt agcgattccc atcagcaaat
     1741 tcatgtaata gggctcagtt gtgtcgattt cttccagtat aaataatttg atgatctgcg
     1801 accgattcgt gacaagtgct tttgcagcaa tatttggacg gtaatccagt tcagccattg
     1861 ctgagaaaac taactctttc aattcgtcag tcacctgttc cggatgattg atgactcgag
     1921 agaccgtcat ttttgaaaca ttggcacgtt ttgcaacatc tgctaaagtg ggcatgctct
     1981 cttcctttct aacatgttgt cattcttact atcaattata ccaaattttc ctaacagagt
     2041 ttattatagc ccaaaataaa aaacggaaaa tcctctatcg tcatgagtga ttttccgttt
     2101 caattattta tactttttta tcaaattttt tgctaaaaaa gtggaagctt cttccattag
     2161 ttgtatttgt accatatgtc gctgtgtttt tgaggaacga aaaacaattt cttttccgta
     2221 agacttatgc cgattttttt ctacaaatcg ttccgtttgt atataaggga ttttttcgtc
     2281 agcttgtcca tgccaaaaga acagaggacg tccagctaac ttttccggct gcaatgacaa
     2341 atcatagctc ttaacccatg aaatcaaatc aaaatagtct tttggtacga cataattata
     2401 ttccgatgcg cgccttacga tttcttttcc atattccaaa ggtgcagggg aacccatcaa
     2461 acacacgccc gctactatat gaggatgttt agccaacaag gcgcatgttg tcattccccc
     2521 catcgaaacc ccgccaactg caagctgatc atgtagaaga cctctttttt ctaaatgctt
     2581 gataagtgtg tcaaattcaa acagatttcc gtagatacta tcccaaaatg tataggatgg
     2641 aatagaagaa accggctgtt tgcgctcccc atgattcatc gcatctggca ggatcacacg
     2701 aatgccctgc tgcgcaattt ttcttccttg cgtcaaaact aactccttac ttgtctgcca
     2761 tccgtgataa tagatgacaa cgggaatacg ttcctctctt aattctttca gaacaacttc
     2821 taacactgga atatgatgga cagaacgttt caatataatt ggattcaatt gttactcacc
     2881 tattttcatt aaatttcctg atcgccatag caaccatgct ccaacagttg tctggaacag
     2941 gttcagtgta ccaaataata taaatgcagg actgaatggc tcgggaaata agcacagaga
     3001 acaaagtccc accactccta atgctagcga aaggagtgga taaatagaaa aattcaaaaa
     3061 actggcaacg ctaccgaaaa tattaccaat aaacagtatc aaaaagaaaa aaacgcttaa
     3121 aattaaacca tctgtcagcg acatctgaaa aacaatgttc tctacctcaa ttggctgttg
     3181 aatcgaatag acacctaagt atatactgag aaggagactt agcacgtggc tggcacaaaa
     3241 cacacgattg accgttttca ttttaatcac ctaacctatc tttataattc tattataatc
     3301 attttatcat ttttttgtat gtataaagtt tcaatttttc ttcacttacg attttttttg
     3361 atattgttgt tatataaatg aaaggagttt tacaaatgat tgatccaaaa atgttgggga
     3421 tgatcttcct cattaatttt gcttatatca ctctgaacac gttacgtttc atgttgacaa
     3481 tgaaaggcta tcgactgatt gctccacttg tcagtatggt cgagatcacg atttatatcg
     3541 tcggcttatc ccttgtttta gatcgtttag ataatccact gaatttattt gtctatgcgt
     3601 taggttacgc agtaggtatc agtgtcggaa ttttgattga agacaaattg gcattaggat
     3661 acatcatggt cacaacgatt ttgccagcaa atagcgcaga agataaaagt ttgccgggta
     3721 tactgagaga acacggttat ggtgtgacac agacttctgc aatggggctg gaaggtgagc
     3781 ggctagttct cgaaatactt tctcctagaa aaagcgaacg tgaactgtat cgcctgatca
     3841 aagaaatcga agagcgtgct tttatcattt cttatgagcc aaaatatatt tcaggtggtt
     3901 tctggactaa aaaagtgaga aaacgacaag gaaaataact cacaaactta aaaactgtct
     3961 aatatctaaa ttaaatttta aatgttagac agtttttatt tattattttg attaaaaaac
     4021 atcgacatat actcatcaat ttgttattat actttatata cttatcaatt taatttggag
     4081 atattatgga aattcaacgt agaaccacta attttttaca tttaggctct ttttttgcaa
     4141 ctttgacgat cttatttttt ctatgttatt cataccttaa gacctcacat gcgccttcta
     4201 gtgcattagg ctggttgctt ttggatcatt ctgatatcac agaagccgaa gaaaatccgt
     4261 tttttttgat tttgtcttct ctttgcggct tactgttttc tgtttatttc ggtgcctatt
     4321 tttttcatcg acatcctggt acgttaaacg aagcttcaag cgtattgatt gcatttaaaa
     4381 cgttttcttt tttagcaatt cttttttatt cgtttaatca caatacgctt ttcttcttta
     4441 tcatgaatgg tttagtcgtg attttatcca tttttactta ttttattttt tcactcattt
     4501 ttagccaatt gaaatgtccg ctcttctttc gattagttcc tgtcacctgt tttatttaca
     4561 gcttgttttc cttttttgtc cttgctttaa tgccactgac caacccttcg acgatccaag
     4621 tcgcaggaaa tctgttggat atgctcttca tcgtcagtct aggtgtattt atgtggcaaa
     4681 gaaaaaacaa acaaaataaa aagcattttg aagcctgact attacgactt cataaatgct
     4741 tttttagttt taaacacttc aatctaaaag aataacccaa gattggataa attattaatg
     4801 actcgccatt cgtttcttag tgattctgga ttatcaaatg gacttcctaa tctaatcagc
     4861 tagttcttcc cataaaatgc catacttgac tgaatcataa tattgattat ttaaaaatct
     4921 aacttttctt atcactactt cctttgtcat tccacatttc tcaccatttt tttgcattcc
     4981 tttgtttcca gaccatgtag tgaatctaat aggtggtaga taggcaaaat actcaaataa
     5041 ttcttttaac cataaaggaa gagaaaggct cctcctgcaa gagtcagtat aatttttgct
     5101 tactgctctc ttaggtttta ctcactaaaa ctgttccata ttctttgata taagaaaatg
     5161 catgcggtat aaatttcttg ctcagctcag aaaagatttg tcgtttaaga aaggccattt
     5221 cctccattgt caatgaagga tccaatgttg gtaattcaat ctcaaaattg tttttttcga
     5281 caataggtaa ttctaatgtg aatgattctt cttcctttat agtattcgtc acaagtagag
     5341 actgatggaa aatactaggc cggcgatttt tatatttatt cttacgtatc ctgtcaacga
     5401 taacttctat ttgatcaaaa aagtacgatt catttacgtc tccaataagt tcggctaatt
     5461 ctttgaatgc cttcgttaca ggaagctgat tcttctgtac aaaaaagtaa ttagccaaag
     5521 taagcgggaa gtgttctata gaggaaagtg tgataaaacg gtacttctca tttcctgcag
     5581 ttgtcctcag caattctgtc tctcggctgt ttcttactcc ataaaaatac gcttctttcc
     5641 gttcatcttc gaaacaatac gcccaaataa cttctcccat cgctaatttt tgttcatcaa
     5701 cagagagtct cttcaattgt tcagctatgg tttcagcagc cgaagtggct tgttgcaagt
     5761 aatctttagg atcaaatatt ggaaagttca aatgatatct tcgttcttcc ctcttgatta
     5821 atcctgcatc gatcaataaa tcaagaaaat gggaaaattt attttgcgaa aattcttttt
     5881 tcaattctct tagaatcgtt tcttgttctc gatgttcata tagataatcg gtcaatgaag
     5941 aaaaaagcgg atcatcggtc agtttttgat aaaagttttc cttatttttt gaataatagt
     6001 tcatatatgt tctcttttct atccgtttta ttttacttaa aaggctttta cgtaaaaagg
     6061 aggaagaaca agagtcataa ttgactgtta ttctcctcca tttcttcggc ctttagtatg
     6121 ttctatgttt ctttttatat caatcgctta tccattcatt ttgaatgctt catactacca
     6181 tttgattagc taaatacagc cgtcaattga ggtacgactt gttttttacg tgaaacgaca
     6241 cctttaagca aagcacggtt gttggtcaaa gttgtttgga aagcttcttc tactttttct
     6301 tttcctttac cagcaacaag taattctgaa tcactgtcta agatgtttgt gacaactaat
     6361 acgaacagat cgtagccatt tgctttcatt tcatcttcca ttgctgcttc tagctctgct
     6421 tgtcgatcca tcacttcatt aaggtccact gtattgactt gagcgatacg aacgttggaa
     6481 ctgcccattg ggaaactttt tgcatccaaa tcaagaagaa ccgcagctga tttatcactt
     6541 agatttgttc ctgctttcaa catttcaagt ccataagtgt ttagatcgac ttcagcgatt
     6601 gctgcaagtt cttttgcagc tgcttcatct tcaggcgtac atgttggtga tttgaacaac
     6661 aatgtatctg aaatgatagc tgagagcatg attcctgcga tttctttagg aattgttact
     6721 tggttttctt tatatagttt taaaataatc gtacttgtac atccaactgg ttctgcacga
     6781 tagtacaatg gattagctgt ttcaaagttt gcaatacgat ggtggtctac tacagctaaa
     6841 atatttactt cgctgatatc tgaaatactt tgttggaatt cattatgatc cacaagcatg
     6901 acatctgcat tttctgcttt agctgactct actactcgtg gtgcagatag ctgaaagtgg
     6961 tctaatgcgt attgtgtttc ttcattaggt gtacctagag caactgcttc tgtttcttta
     7021 cctaattcat tttgcaagtg tgaaaacgca atggctgccc cgattgcatc tgtatctgga
     7081 ttttggtgac caaaaactaa aatttttgac atgtcattcg ctcctttgtg atttctccta
     7141 tttaataata gcaaaaaaac ggaaagaagc aatacttatc ttctttccga tgcgacctat
     7201 cgcgttaaat attttgtata ctcttctgta tgaagcaatc gtttagcatt ttcgacacgt
     7261 tcttttgtag gtggttcgat cccttctaat ggatatttca aaccaagtgt ttcccacttg
     7321 tattttccca tcgtatgata aggaagaatc tctactctgt ctacatttga caaggtttga
     7381 ataaagttgt ctagtcggat caaatattca tcataatcac ttcgctcagg aactagtaca
     7441 tggcgaatcc aaaccggttt gttgattttt gacaaatatt gagccatttc taaaatattt
     7501 tcattgtccc aatgcgttag ttttttatgc tcttcattat cgatgtgttt gatgtcaaat
     7561 aacagtaaat ctgtatactt catcaattct tgaaaacgtg aaaagaaagg ttcttcatac
     7621 gtaaaaggtt ttccgcatgt atccaatgta gtatgcatct tccgctcttt tgctttttta
     7681 aatagttcga tcaaaaaatc gatctgcaat agaggttctc caccactaac agtaatacca
     7741 cctttatctc cccagtaagg tctgaagcgt tctgctttat ctaaaagttc atctgctgtg
     7801 tattctttcc ctccgccaat attccaagta tctggattgt gacaaaattg gcaacgcatg
     7861 cggcatcctt gcataaacac gacaaagcgc agtccaggtc cgtctactga accgaaagtt
     7921 tcgatagaat gaacatagcc gattgttttt tcttccattt aagttcacat cttttctttg
     7981 atttcatttt aagtacaagt tagctgtcga agcgaagctt tctgaacaaa atttttcgca
     8041 attgccgctt cgttatgtgt aaaatttaca gggacggaac atacaagtcc tgcccctgta
     8101 aatcgtttct ttcaaataag catactgatt attcgatttt gatgcgatgg ctattcaacg
     8161 tcctttcgac gctaagtcga aaaacttttt tcacgaactt tttacattct gtcgtgtgaa
     8221 gttctcatca agacatctaa ttgttgttct cttgtcaagt cacggaattt aactgcataa
     8281 ccagataccc ggatcgtcaa gttcggatat ttcattggat tttccattgc atcacgcaat
     8341 aaatcattac tgaatacatt gacattcaaa tgataagctc cttttgagaa gtatccatct
     8401 aagacattac gcaagttttc gattcttgta tcttgttctt ttccaagacc tgaaggattg
     8461 attgtttggg tatttgaaat tccatccaat gcacagccgt aattcatttt agctgttgag
     8521 ttcaggctag ctaataaccc actttgttcc gcattgtaac ttggatttgc tcctggcgca
     8581 agtggttttc cagcttcacg gccatcagga gtatttcctg tatttttacc gtaaacaaca
     8641 tttgaagtaa tcgtcaataa tgaagttgtt ggttttgagt tgcggtaagt tttatgacgt
     8701 ttgatttgtc ccatgaagta ttccaagatc catgaaacta attcatctgc acggtcatca
     8761 tcatttccgt atttagggaa gtcgccatcc acttcaaaat caactgctat tcctttttca
     8821 ttacggattg cttttacttt tgcatatttg atcgctgaca agctgtctgc cgcatgagag
     8881 atcccagcaa tacctgtagc aaatgtgcgt tgcaagtcag aatccatcaa agccagctga
     8941 gctgcttcat aagaatattt atcatgcata taatgaatga tgttcaacgt attgacatat
     9001 agttctgcta accaatccat catattcatg aagttatgtt tcacttcttc aaagtctagt
     9061 atttctgatg tgattggacg atattctggt ccaacttggg cgccagtcac ttcatcgact
     9121 ccgccattga tggcatataa tagtgtttta gccaagttag cacgagcgcc aaagaattgc
     9181 atgtcttttc cgacaactgt tcctgataca cagcaagcaa tcgcacaatc atcagaaccc
     9241 cattgttcac gaagctgatt atcattttcg aattgaatcg aagaactttc gatagcgatt
     9301 ctgctagcat atgttctgaa tccttctgga aggtgttcag aatacaaaac agtcaagttt
     9361 ggttctggtg aaggtcccat atttgttaat gtatgaagca gacggaaatc attctttgta
     9421 actaatgaac gaccatctaa tcccatacct gcaatggata aagtagccca gatagggaat
     9481 cctgagaata attggttata ttcaggtgta cgcgcgaatt tgaccatacg taatttcatt
     9541 actaagtggt cgatcaattc ttgtgcttct ttttctgtga ttactccatt atccaaatca
     9601 cgttggatat agatatcaag gaatgctgag atacgtccga ttgacatcgc agcaccattt
     9661 tgtgatttga ttgctgctaa atatccgaag tatagccatt ggacagcttc ttttgcattt
     9721 gcagctggtt tagaaatatc atagccatat ttcgcagcca tttctttcat ttgcgctaat
     9781 gcacgatatt gttcagtgat ttcttcacgt aaacgaatca cttcttcact cattgtatga
     9841 taaccagtca tatcatgatc ttttttcttt tgttccatca aatagtcgat tccatacaat
     9901 gccacacgac gatagtcacc gatgatacgt ccgcgaccgt aagcgtctgg aagccctgta
     9961 atgattttgt ttttacgagc agcacgcatt tcagcagtat aagcgtcaaa tacaccttga
    10021 ttatgtgttt tgcgccagtc agtgaaaata tgtgtcaatt catcgtttgg tgtatagcca
    10081 ttgcttttta gcgcattgtt agccatattg attccgccga acggcatgaa tgcttgtttc
    10141 aaaggtttgt ctgtctgtag accgacgatt ttttccaaat ctttatccaa atagcctgca
    10201 tcgtgtgaag taatagttga tacgatttct gtgtccatat catagacacc gttacgctcg
    10261 aattggatat catttaactt ttgcaattca tcccataatt tttctgttgc ttctgttggg
    10321 ccttccaaaa agctgtcatc accgcgatat tcagtgtagt tattttgaat aaagtctcta
    10381 gtgtctacgc cttctttcca tttggtacct ttaaatccat tccattgctc cattgtatgg
    10441 acctcctaaa tttctgtttt atgtaacagt ttttacgtga ttagtataac acagcaccct
    10501 atctttgcaa gggttttctt gttttttatt taacaatttt tatgttttat ttacatatat
    10561 ttaaatcaac gttgacatac caacatttaa gcattgtgaa cactttcatc tttttttgca
    10621 aacgtataag gatttattaa aaatgaatga aaaagagacg ccacctgtat taatacagat
    10681 ggcgtctctt cattaaaata ctacaacagt tacgactcga tgaaaatctc aggagcatcg
    10741 ataacttcga tgacttctcc accttttttc tcatccatcg caaatgatcc attcgatgtt
    10801 cgatcaccta tagggaaatc agttgggtca atcgttaact gctgcccttt ttgattcatc
    10861 aaggttattt cttttgatct tccttccgac atatagataa tacggtgcgg attttttttc
    10921 agctcacgca tgaccgtcac tccccgcttc gcacgtgaag tttggctgat ttcttgagca
    10981 agcatgcgtt taacagctcc tcgctgagta acgattacga tcggcgtatc accttctgct
    11041 aacacaagca gcccgttgat aatcctatct ccatctttca aattcataga cttcactcca
    11101 gctgcctttg ctccaacaac gggaacatct gttaaaggat agcgcaaacc cattccttga
    11161 tgcgttacta agaaaacatc taagcctggc tgatcttctt tcagatacac agcaatcagt
    11221 tcatcttctt ccgcctttag cttcatacag ctgagcggac ggctcttata ggtgcgccat
    11281 ggttcgaact ctgtcattcg tgtttgcttg atcaatccat tcttgctgat gaatacaaat
    11341 gttttctctg cttgaatttt ttgatatggg aaaacagcta aaatcgattc gtctacagac
    11401 agattggaga ttgtttgaga aatgtgctca ccagcatctt tccatttcaa atcgggtagt
    11461 tcatggacag ggcggtagat cacatttgct ttatttgtga tcagaagaac atggtccaat
    11521 gtactcaatt cacctgagta tagcaagtag tcgccttctc gcatcccgat ttcttctggt
    11581 ttggaagcac tataagaacg aaggcttgtt cgcttcacat agccttctcg cgtcacactg
    11641 acaattacgt cttcttgtgc cactaagact tgcgtatcaa ttttgatttc ttcgatttcg
    11701 tcttcgattg tcgttagacg agcggaagaa taattttttt tcacttctcg caattctttt
    11761 ttcataacag agaaaagctc tttgtcattt gaaaggattt tattcaactc tgtgatttgc
    11821 gcaatcaagc tttcggattc cttttgaagc tctgtgatat ccgtgttcgt caaacggtat
    11881 aattgcaatg tgacaattgc ttctgcttgt tcttctgtaa attgaaagac gtcgactaaa
    11941 ttctttttgg cgtctttttt gtctttactt tcacgaatcg ttgcgattac ttcatccaga
    12001 atcgataaag ctttcatcaa tccttctacg atatgctgtc ttttttgagc tttggctaaa
    12061 tcgaattgac tacgttttgt tatgacttgc tttcgatgct cgatataact tcttaaaatg
    12121 tctttcagtc caacttgatg cggagtcata tggtcgatag cgaccatatt gaaattgtaa
    12181 ttgatctgta gctcagtgtt tttgaacaaa taattcaaaa ttccttgagc attggcgtct
    12241 tttttcaatt cgacgacaat ttgcagacct gttctatcac tttcatctcg tacttcagct
    12301 attccatcga ttttcttatt caaacggatc tcatccattt ttttcaccaa ggtcgcttta
    12361 tttacttcat atgggatttc tgtgatcacg atttgctgtt tattaccctt cattgcctct
    12421 atctttgttt tcgaacgaag aataactttt cctcgtcctg tttcataagc ttttttgatt
    12481 tcatcttttc cttgcaagat ccctcctgtt ggaaagtcag gtccaggaat atattccatc
    12541 aatttttcaa ggctcgcttg tggatgatcg atcatataga ttgtgccatc gatcacttca
    12601 gctaagttat gagtcgggat ttctgttgca tatccagcag atatacctgt cgatccattg
    12661 acgagaaggt ttgggtatcg agctggaagg actgttggtt ctttttctgt atcatcaaaa
    12721 ttccacacga gatcgactgt ttctttctcg atatctgcta gcatctctcc acttaacttg
    12781 gataatctgg cttcagtata acgcatcgca gcaggtggat caccgtccat actcccgtta
    12841 ttcccgtgca tttcgatcag tacttcccgc aacttccagt cttggctcat gcggaccatc
    12901 gcttcataaa tactgatgtc accatgagga tgataattcc ccatgatatt tccgacagat
    12961 tttgctgatt tacggaatcc tttgtcatac gtattgccat ctttgttcat ggcaaataat
    13021 atccggcgtt gcactggctt caatccatca cggatatcag gcagtgcacg ttcttggata
    13081 atatatttgg aataacgtcc gaagcggtca cccatcactt cttctaaagt taattcttgt
    13141 acttcttgtc gattttccat caggtgacct cctattctac ttcaaataac tgattgtttt
    13201 catttttatc tgctcgttct tcatctaata aatcattaga aactgaagga gagatttcag
    13261 tatcctcttt tttatctaag atactgccat cttcttcgag cgtaaattgc acgtgatttt
    13321 cgatccattt tcttcgaggt tctactttgt cacccatcag tgtggttact cgacgttcag
    13381 cttgcgcagc atcatcgata cggacgcgga tcaacgtacg ggaagtcgga tccatcgttg
    13441 tttcccacaa ttgttccgca ttcatctctc caagtccttt atatcgctgc agcatatatc
    13501 ctttgccgac ttttttaatc attgctgcca attcgtcatc tgtccacgca tattcaatga
    13561 cttgcttctt tccttgtcct ttggatactt tatataaagg cggtaacgcg atatatactt
    13621 tcccagcttc aatcagcggt ttcatataac gataaaagaa agtaagcagt aatacttgaa
    13681 tatgggcgcc gtctgtatcc gcatcggtca tgatgattac tttgtcgtaa ttacagtctt
    13741 cgatagaaaa ctcaggaccg actcctgcac caatcgtata gatcatcgta ttgatttctt
    13801 catttttcaa gatatcttgc attttagctt tttcggtatt gatgactttt cctcgtaaag
    13861 gtagaattgc ttggaacttt ctgtctcttc cttgtttagc agatccgcca gcagaatccc
    13921 cttcgactaa atacaattca tttttcttag ggtttcggga ttgtgcgggt gtcaattttc
    13981 ctgaaagaag agattcgcct tttttacgct tcttcccatt tcggctttct tctctggctt
    14041 tacgtgctgc ttctctcgct tctctggctt tgattgcttt acggaccaac atctggctca
    14101 tttcgctatt ttcctgcaaa taaaagccca tttgttcact gatgacgtta tctactacgg
    14161 tacgagcaac tggcgtacca agtttttctt ttgtttgccc ttcaaattgc agaagatttt
    14221 caggtacacg gatagaaagt acagcagcta acccttctct gaaatcacta ccttccagat
    14281 tcttgtcccg ttctttcagc aaaccaactt ttctcgcata ttcattataa gatttcgtca
    14341 tcgccgcttt cataccagct tcatgggttc ccccatcttt tgtccgaacg ttattgacaa
    14401 aagataaaac attttctgaa taaccgtcat tgtattgata agcgacctct acttcgatac
    14461 cttctttttc tcctgaaaaa taaacaactg gtgtcaatgt atctttttct tcattcagat
    14521 aatcaacaaa ttctttgatt ccttcttcgt aatgaaaaat ttccttgact ggttcttctc
    14581 cacgaagatc agaaagagag attttaacgc cttttagaag aaaggcagat tctcttaacc
    14641 gttcggctaa aatttcatat gaaaatttcg ttgtactgaa tattgtatca tctggtaaaa
    14701 aatggacagt cgtcccgttt gctttttttg tttttcctat ctttttcaaa gtaccgtcag
    14761 gtttaccgcc gtttttaaat ttctgctgat actctacgcc atctctaacg atcgttacaa
    14821 ttagccattt cgataaggca tttaccacac tggctcctac accgtgcagt ccaccagaag
    14881 ttttgtaccc tccttgacca aactttccgc cagcatgcag cacagtaaaa atcacttcaa
    14941 ctgttggtat tccggaagca tgcattccta caggcatccc acgtccgcta tctgcaacag
    15001 ttatactatt gtcttcatgg atggtcacat caatctcact gccataacct gataatgctt
    15061 cgtcaactgc attatcgacg atttcataga ctaaatgatg caagcctcgg ctgtcagtgg
    15121 atccaatgta catccctggt ctttttctaa ctgcctctaa tccttccaat acttggatgg
    15181 acgagtcatt gtattcgttg tttacttttt ttgccaaggc aaacgctcct tcaataatac
    15241 tttgcggcaa aaccgcacca cgattatcat actagaaaag gtcgtgaaaa aaaagagggt
    15301 agacgagaaa tcaattttaa ttatctccta accgcttttt cgacattccc ctctatcgat
    15361 catctcttct ttgtggtcat ttttattttt ggttttcttt caacttacca agttcaatct
    15421 taatacaacg atccattacg atatctgtac gtcctgcttt tcttagcatc tcagctgctt
    15481 ctttgttttc aatccctaat tgtgcccaga acactttagc atcagttttc aaaaaatcac
    15541 ctgctatttc aggtaaaaat tcactccgtc taaatacatc tacgatatcg attggatcat
    15601 cgatttctgt caaattcgca tagactttct cgcctagaat ttcttcacca gccaataatg
    15661 gatttactgg tatgatttta tatccattgt cttgcaatac ctgtgcaacc atgtaacttg
    15721 ttcgttctgg tttattgctc aagcctacga cggcaatatt ttttgcttct tccaaatagt
    15781 tgaaaatcgt ttcttgtgtt ggatttttta cagacatttc tgccacccct tgcttttctt
    15841 tttattccat ctattatact tgtatctttc attttttcaa ttgttcctgt tacctattca
    15901 tgctaaaata aaggatagtt ttcaacttga aagagggtaa aaaatgaaat tgatcttatt
    15961 acttatttta gcatatcttt taggttctat tccttccggt gtctggattg gcaaattgtt
    16021 tttcaaaaaa gatatccgac aacacgggag cggtaatact ggaacgacca atacatttcg
    16081 tgtattaggc aaaacagccg ggattgttgt cctgcttatg gatattttaa aaggtacatt
    16141 ggctacttgt ttgccgatga tcttccacct ttctgggatt aaccctcttt ggtttggggt
    16201 atgcgccatt cttggccata catttccgat ttttgctggg ttcaaaggag gaaaagctgt
    16261 tgcgacaagt gcaggaatgc ttttaggatt taatcctgta ttttttgttt attcttgtat
    16321 catctttatc gttagtttat tttgtacaag tatggtgagt ttgagcagta tgatcagtgc
    16381 agtattgatc actttatcta cgatcgtcct tccttatgta gctcctgtga ttttggctaa
    16441 gcccaattgg ttactgacga tcattgcctt tttagtttct tcctttatct tttatcggca
    16501 taaagacaat atcaagcgta tcagaaacca tactgaaagt cgaatcccgt ttggtttgaa
    16561 tagcagcaag aaaaaatcct gatacttttt cattccaaag agataaaacg ggagtgtgac
    16621 aaatcgatgt cacactccct tattacttac aggatagctt ttttacacac cttggtaaac
    16681 ggtgttccct gctaacttct cggtcacaac ctcttacttc actgtgatgg aatattttgt
    16741 cttgaagatt tcatgggcac ctagttgatt gatccctact ttttccatca agtttccact
    16801 actgttcacc gtgtcagcga ttccgcacca cggttcgata caaacgaaag gcgcttcttt
    16861 tggataagga gaccagatcc ctacataagg catatcttta tagcttaaag ttacgctatg
    16921 ggaagatttt tcacttcgaa tggcgtacgc atttagaccc cttgtttcaa aaaccaaggc
    16981 atcttgctca aaaagttcac gattcaaagc cagattcgta tttgtctgac ctaacgtctt
    17041 ttgatccata tcgatgaatg ggcctttcaa tggtaggcgt aatcttgatt tcaatggaga
    17101 aaatgccaga tagaaatctt caaatgacaa tccttcttca agaggtacat tgaaagcagg
    17161 atgtccaccg atagaaaaga acatttcttt ttcaccggta tttgccactt gataatgaac
    17221 cgtgatgccg tctcctccta attcatagct gatcactaat tcaaaatcaa atggatactt
    17281 ttctaatgtc tccggcgtac tccttaagat gaaactagcc atttcttgtc catgttcaat
    17341 gacttcaaaa tccatatccc gagcaaatcc gtgttgcccc atttgatatg ttttcccttg
    17401 ataaacatac tgatcatctt ttaaacgtcc aacaaaaggg aataaaaccg gtgcatgtct
    17461 gccccaatac gctggatcac cttgccagat atactctaaa ccatgttctt ttgatttcag
    17521 actgatcaat tccgcaccgt gttcagcgat ttcggcgatc agctggtcat tttgaataat
    17581 aacagtcatt gccattcctc caacttcgac ttacttttta aaatgggaag gctggaacaa
    17641 acatttctat ctgccccagt ccccttactt ctaataactg tgttttgcta actcgtcttt
    17701 aaaacgggaa ttcaatactt ttaaataagt tcccttcatg cctaacgaac gagattcaat
    17761 gattccagct gattccaatt ttcgtaaagc attgacgatc acagaacgag tgatgccgat
    17821 actatcggca atattagaag cagtcagacg accttcatct ccatccaatg cttcaaagat
    17881 agcttgtaca gccttcaatt cgctataaga taatgtgttg attgccattt ggacagccgt
    17941 tgcactccgt acatctgctt cgatgcttcg agacttctga taaaggatct gcataccgac
    18001 aaccgtagct ccatattctg ctaagactag atcgtcatct gcaaacgatt gttccatacg
    18061 agataagata atcgtaccca aacgttcgcc agctccaaag atcggaacga cagtcgtcag
    18121 accaaatgga tatttctctc ttgactctac cggaaatgca gtaatatcac tagtaattgg
    18181 gatattagct tcagttttca tcaactgtgc cactgtatca gtataagatt caggaaattg
    18241 tttctcaaca aacattgttt tgattcgttc attgttcaca tcgtgacgtt cattataacc
    18301 tagtaatact ccgtcacttc ctatgatata ggtgttgctg tcaagaatac cacctagtgt
    18361 gacagccatt ttatcgtaag gcaaatctgc ttgcatgtca aaagtattct tttgctgcaa
    18421 aagtgtgttt atcttgcggg ttttcgttag caagtctgtc attgtcgtcc tccgattttt
    18481 tataaaatat agcgacttaa atcttcattt gccgcaattg agccaagttt gtcatccaca
    18541 tatgcttctg tgatcgttat ttctcccatt tgcatatctg gtgcttcaaa taatagatct
    18601 tctagtagtt tttccaaaat ggtatgcagt ctgcgtgcgc cgatattatc tgtgtcacgg
    18661 ttgacatcga aagcgatttg agcgatccgt tcaattgctt cttttgtaaa cgtaactgac
    18721 acattttctg taccgatcaa cgcgacgtat tgttttacta aagcattatt tggttcggtc
    18781 agaatcttca caaaatcttc agctgtcaaa tcatctaatt ctacccgtat cgggaagcgt
    18841 ccttgaagtt ctggaattag atcacttggt ttagacaaat ggaaagctcc tgaagcaatg
    18901 aataggacgt gatctgtttg gatgatcccg tattttgtgt ttacttgtga accttcgaca
    18961 attggcaata tgtctctttg gacgccttct ctggatactt ctccagattg ctgtgattta
    19021 gaagtgatct tatcgatttc atcgataaaa ataattccac tttcttccgc taatttgatt
    19081 gcctcactat ggatatcagc atccttgact aattttgctg attcttcctt gatcaataac
    19141 tctaaagctt ctttgactgt taccgtccgt tccacttttt tcttcggtgt caaagcacct
    19201 agagtttcat ttaggtcgat ccccatttgc tccaatccat tgttcatcat tggtgcaggt
    19261 ttcttttggt cttcaacttc aatggttact tcacgactat ccagtaaacc cttttgtagt
    19321 tgttccaaga ctgtacggcg attgattcga atatcttctg tcacttcttc ttgcggttca
    19381 gcggtatttt gctgactagc attaaaaaga ttcatcattt gttcaaattg attagtggat
    19441 tgtttctgtt cttttttgat accaggtacc aagattttta ccaaacgttt ttctgcattt
    19501 tttttagcac ttgtgtatac acggctgtac tgctcttttt ctacgatttg gatcgcattt
    19561 tctactaaat cccgaaccat tgattctaca tctcttccga cataaccgac ttcagtaaat
    19621 tttgttgctt cgactttgac aaatggtgca ttgacgattt ttgccaaacg tcgtgcgatt
    19681 tctgttttac cgacccctgt aggtccgatc atcagcatat tttttggtgt aatatcttgt
    19741 tgcatttttt catctaactg caaacggcga tagcggttac gcaaagcaac ggcaacagat
    19801 ttttttgctg cgtgctgtcc tacgatatat tcatctaatt cacttacgat ttgtcttggt
    19861 gtttgtttta attcatacat atctactcac ctcttacagt tcttctacga taatattatg
    19921 attagtaaag atacagatat ctgcggcaat atttaacgca ttttctgcaa tttctttcgc
    19981 actcatgtcg ttttgagcat agtttttcat tgctcgggct gcagccaacg caaaattccc
    20041 tcctgatccg atagctaaga taccatcatc tggtgtgata acttctcctg tacctgaaac
    20101 aagaagcatt tctttatcat tcattacgat cagcatcgct tcaagttttt gcatagattg
    20161 ctgtgtccgc cattcttgag ctaattcgac agctgcgcgt tgtagattcc cgttatattc
    20221 gtttagtttg ccttcaaatt tttcttctaa agtaaacgca tctgcaacac ttccggcgaa
    20281 acctacaaca acttctccat tgtagatacg tcgtactttc tttgcagtgc ctttcatgac
    20341 aacagattca cccattgtta cttggccatc tccagccata gcaaatttcc cgtctttttc
    20401 gacggcacag atagtggttg aatgaaatgg tgattcgacc atgtttgttt cctcctaaat
    20461 ttgttctttt ccttattttt acgctcttgg atggaaagaa cgatagtttt tttgtaaact
    20521 ttcttttgtt acatgggcat agatctgggt agtcgataaa ttggcatgtc ctagcaattc
    20581 ttggactgtc cgcaaatctg ccccattatt taataaatga gtagcaaatg tatggcgcag
    20641 catgtgagga tggatatcac tatccaaact gctttttttg atcatttgat tcaagacata
    20701 ttcaattcca gtaggcgtga ttggttttcc atgatgattc acaaaaacga tatcatgctc
    20761 ttcgtgatat tttgtcatca atacctggcg gccttccctg aaatattctt gcagagcatc
    20821 ttgagcaaaa gaacctagag gagcatatct ctctttgttc cctttaccat ggatcaacat
    20881 gacctctgaa tcaaaatcaa tgtctgatac cgacaaactg ctacactcac ttaaacggat
    20941 gcctgacccg taaaggactt ccagtaaagc gcggttcctc aaatccaaag gactatctcc
    21001 tgctacgctg tcaaaaagtg cttgcatttc attttcataa aaaaaacgtg gcagtctcaa
    21061 atttttcttt ttgagatgaa cgtaagaaaa tggattttct tttatcactt cttctttgag
    21121 aagatactga taaaacgaac gtaggctggc tatcttgcga ctgatagaat ttctgctata
    21181 gctaggacga tgatcagcta atgcactcaa atagacacga accgtaaaat attccgcctt
    21241 cagcagatca gcgtctccag attcctccaa aaaatgtttg aaatggagaa tgtcttcttc
    21301 atatgcttct ttcgtttttt ctgaatatcc tctttcgaca atcaaataac gcaaaaattt
    21361 ttgttcccac gtggcttctg tcattttctc accttccttt tgtcccagag aataatttag
    21421 cacagcgttt ataaaaagac aaataaattg tcagaattta accaatattt ctaagtttgt
    21481 tcacaattgg cgcaattcct cacattttgt ttgagaaatt cttaagaaaa acgcaagaaa
    21541 aagagcgaga ctatccgtct caccctcttc atggagtttc cttactcatt tgggattgca
    21601 gttttttcta attctgtttt tattgcctca ttagctttta aagctcgttg tgcaattgct
    21661 tcatatcttg cttttttgtc tcgaatgcgc tctggcagtt caggaaacag accatagttg
    21721 gcattcatcg gttggaaatg ttttccttcc gcatgagtaa tgtagtaagc catacttcca
    21781 atagctgttt cttgtggaaa ctcgactggt tccatttctt ttgctaagcg tgcggcgttg
    21841 attccagcaa gtagtccgct cgctgcactt tcaacatagc cttctacacc agtcatctga
    21901 cctgcaaaga acagatcttc gcgtttcgtt gattggtaag tcggtttcag caattctggc
    21961 gaattcataa agctgtttcg gtgcatcaca ccatagcgaa cgaattcagc attttctaac
    22021 ccaggaatca tccggaaaac acgtttttgc tcgccccatt tcaagtgagt ctgaaagccc
    22081 acgatgttgt ataaagaagc tgcagcattg tcttgacgca gctggataac agcataagga
    22141 cgtttgccag ttttaggatc ttccaatcca actggtttca taggtccgaa aagcatcgtt
    22201 ttgaatcctc gctgtgccat tacttcaatt ggcatacatc cttcaaaata tttttctttc
    22261 tcaaaagatt taagttctgc cacttcggca ttgattagtg cctcatggaa agctttgaat
    22321 tcctcttctg tcatcggaca gttcaagtaa gctgcttctc ctttgtcata gcgggacttc
    22381 aaatatactt tatccatatc gatcgtagct ttgtctacga ttggtgcagc tgcatcatag
    22441 aaataaaaac catctgaacc attgaatgct ttgatgcttt ctgctaatgg atgagaagtc
    22501 aaaggtcctg ttgctactac ggtgattcct tccggtattt cagtaatttc ttcgtttatc
    22561 actgttacta atggatgctc tttgactttt cgggtaattg tttcagaaaa agaatcgcgg
    22621 tcaacagcta aggcaccacc agctggcact gctgtttcat ctgccgaagt gattactacc
    22681 gaattcaatc ggcgcatttc ttctttcaat aaccctactg cattagccaa actgtttcct
    22741 cttaatgaat tggaacatac tagttcagca aaattacttg tgtgatgcgc ctcagtcgat
    22801 ttgactggac gcatttcata taaacggaca gggactcctg cttgtgcgat ctgccaagca
    22861 gcttcacttc cggcaagccc tgctccaaca acatttacca ttttcaatga aagaacctct
    22921 tttctattat ttttggatgt cttcttcgta atctccattt acacagacta cttgtttacc
    22981 gcctttgact ttcttctcga ccagatatcc gtcacatttt ggacaatttc tgcccactgg
    23041 tttatcccaa gaagtgaatt cacattctgg gaaacgggaa caaccataga atagtctgtt
    23101 tttcttagat tttcgttcaa tgacttgtcc ttcatgacat actgggcaag tcacaccgat
    23161 ttcttttacg attggtttcg tattccgaca atcaggaaaa ttactgcaag cataaaactt
    23221 cccatatttc cctaatttta tcaccatcgg atgtccacag acatcacaat cgaatcctgc
    23281 tggttcatct ttgatttgaa ttttttcgat tttttcttcc gcattcgtca gttctttttc
    23341 aaacggttta tagaaacgat caaccacttt gacccacgct tccgtgcctt cttcaatttt
    23401 atccaaatct ccttccattt ctgctgtgaa atggatatcg acgatttgag ggaagaattc
    23461 acagattaat gaattgacaa tttctcctag ttcagtcggc tcaaatcttt tttgtgtcaa
    23521 ttttacatag tagcgtcttt ggatcgtatc aagtgttggt gcataagtgg aaggtcgccc
    23581 taccccgttt tcttctagtg cacgaatcaa cgtagcctca ctaaaacgtg ctggtggttg
    23641 agtaaaatgt tgttttggtt caatatcaac agattggact acatcgcctt cttcaagttc
    23701 tggaagaata ttttctttct cttctttgcc gtcatctcta ccttccacat acacttgcat
    23761 gaatcctttg aatttgattt ttgaaccgtt cgcaatgaag atgacaccat tttgttctaa
    23821 tgtcactttc attgtatcta aaatagctgg tgtcatctga ctagccacaa aacgtgacca
    23881 gatcaatgta taaagtttca attgatcttt atctaaatat tgtttgagtt catctggtgt
    23941 acgaagcaca ctcgttggac gcacagcttc atgggcatct tgtgcgcctt gagcattttt
    24001 gatctttcgg tgatcatgtc tagaaaattc ttttccatac gtatcttcaa taaatgctgc
    24061 ggcctctgct tttgctgtat cggcaatccg ggtagaatca gtacgcatgt atgtaatcaa
    24121 gccgactgtt ccttgtttac ccaaagtgat tccttcatat aattgctgtg ctaccatcat
    24181 ggtttttctt gttcgaaagt ttaacttacg ggcagcttct tgttgcaggc tacttgtagt
    24241 gaaaggattc gcagggtttc ttttgcgctc tttcttttct acttttttaa cttcgaagtc
    24301 tgttccatca attctagcag tgacttcttt tacactttgt gcatctggta atttcttttt
    24361 cttaccgtcg attccccaga aatttgcttt gaatttcttg cgagcttttt taaaattacc
    24421 gtcgatgctc caatattctt ctggaacaaa ttctcggatc tctttttcac ggtcaataat
    24481 aatttttaaa gcgacagatt ggacacgtcc tgcacttaac cctttcttga ccttacgcca
    24541 gagaatagga ctgatcgaat aaccaacgat tctgtctaag gtacgacgag cttgctgtgc
    24601 atctactaaa tctacatcga tcgttcttgg ttccttaaaa gctgctttga ctgcgtcttt
    24661 tgtgatttca ttgaagacca cccgattttt ttctttcaga tccaacccaa gtaggtacgc
    24721 taaatgccaa gcaatcgctt ctccttctct atccgggtca cttgccaagt aaactttttg
    24781 agcttttttt gctgcggctt tcaggctttt gatgacatcg ccttttccgc gtatagaaat
    24841 ataatggggt tcataattgt tttcaaaatc gatacccatt ttacttttcg gtaaatctct
    24901 tatatggcca acactggcca ttactttata gtttcgtcca agatatttct caattgtctt
    24961 ggcttttgca ggtgattcta caatcactaa atatttatac gccattactg aatggactcc
    25021 tttccattgt cgtgttccta ctattaaaag aggattcata caaatcgtag ctaatcatat
    25081 ccattcagaa aacgtttgtc aagaaaagca aatgaaaagt atggtgttat tctttaaatt
    25141 ctgccaagat atcttcaccc gaaaccgtgc aaactgcacc gtcttggatc aaatgatgac
    25201 atccggtaga atgttctgtt aaaatatttc ctggaacaga aaaaactgtt cttccaagat
    25261 ccaatgcttg ctgtgctgtt atcagagagc cgcttttttt cttggcttca aagacacatg
    25321 ttcctttaga caaagctgcg ataatccgat ttctcattgg aaaacaatgc tttttcgggc
    25381 cggattgagg aggatattca ctcaaaagaa gatgatcatt tgcaatcacc tcttgcaagt
    25441 cacgattttc agcaggatag acttgctcta tccctgttcc aatgactgcg attgtccgtc
    25501 caccatgaga gattgctgct tggtgaccgt atgtatctat ccctttcgcg cagccactga
    25561 cgatcacata tccagcttct atcactggtt ttagtaaata ataaactgtt tttttggcta
    25621 aagcagaagt gtgtcttcca ccaacaacgc ttaacatgtt acaagaaagt aaagatagat
    25681 caccattata aaacagtaca attggcggat aggtcaagtg aagcagctga gggggatatt
    25741 tgggatcaaa gcaagtgata aacgactgtt tcgattggat tttgccccag ttagcgtgaa
    25801 tttcctgcca acttttgcga aacagctccc ggtgtttggt tattttacct atcttaatga
    25861 tgtcttcaaa tccgatttct ttataaggat actgcatcat ccagttagca agtgcccatt
    25921 ttccttgact actgattcct tttgtataag caagtttcaa taaattttct tctatttgat
    25981 acatcataaa accgcctttc gtctctcttt ctaataagat acgtaaaagc ggctgttttt
    26041 tattgtaaat atttttttac aggtgcaaaa cttttacgat ggattggcgt aattccttgt
    26101 cgttcaagtc cttctaagtg ttcctttgtt ccataacctg cattatgcga gaaaccatat
    26161 ccaggataaa gcacgtcata ttctttcatc aattggtctc gatatacttt agcaatgata
    26221 cttgcagcag caatcgacac agatcgtgca tcccctttga ttattttttc ctgctgaata
    26281 ggcaaatcca aggtcatcgc atcgatcaac aaatagcttg gtacaatgga caatttttct
    26341 actgcttgga tcatcgctaa tttacttgct tcataaatat tcacatcatc gattgtctgc
    26401 tgatcaacga tcccgatccc gattgccagg gctttttctt gaacttgttg ataaagaagt
    26461 tctcgctttt tctctgataa ttgtttggag tcattcagcc ctaatatgat ctcatttttc
    26521 ggcaagataa ctgcagctgc cacgacaggt ccagctaatg gtcctcttcc tacttcatca
    26581 atgccggcaa tccattggtg accttgtgcg tacccttgct tttcaaagca aaacatttct
    26641 tcatattttt ccttaattaa tgcttccttt ttcaatcgtc gttcaaaaga agccagtgct
    26701 tgctgcacgc ctttgcgtgg atcatttctt aatgattcta gtgtaggatc atctattctc
    26761 tgtatgcttt tcaatcgttc tttgatactt tggatggatt cagtcatcac ttttttgctc
    26821 catttcttcg caacgatcca gtgtgtatcg tccaagtttt ccttgacgaa tatcatgcac
    26881 gactaattcg ctgccacgat catagtcttc tttataccca cgttttgctg taatatccat
    26941 cagtaattcc ggtgccaatt tttcttcttg ctcgattgat aaaccataac gatcgctgat
    27001 tcttcctgaa taatatcggg caaaaaagtc taatccgtaa atcgctaaat catctaaatg
    27061 gacaagctgg tctttgatcg cgcctgtcag cgctagtttt ttgccgattt cttcatcttc
    27121 aaatttgggc cataaaatcc ctggtgtgtc taacaattcc aactcattac ctaaacgaag
    27181 ccactgctga ccttttgtta cgccaggctt atttcctgtc tgtgcaattt tcttgcctac
    27241 tagtcgattc atcaacgtag atttcccaac atttggaata cctaagacca ttgcccgaat
    27301 agcgcgaggc ttgatccccc gagcagcatc tcttgcccgt ttttctttca atgcttcttt
    27361 agccgcaggt actagacctt taattccttt actttcttgt gccgtgatag ctaatgcaag
    27421 atggccttgt ttacgaaaat attcttgcca cagctttgtc tgttgtggat ctgccagatc
    27481 cgctttattc aataaaacaa ggcgaggttt ttgctgaatg atctgatcta gcattggatt
    27541 acgagaagat aaaggtaatc gtgcgtctac caattcaaat acgatgtcca catatttcat
    27601 tttttcagaa acttctcgtc gggcttttgc catatgtccc ggaaaccatt ggatggtcat
    27661 tgttctctcc attcctttca taccggaata ttccccggct ttacttgttt ttttcttttt
    27721 caatataaat tcactttttt attataaaga aattccatct attagttaag tgaaagtgaa
    27781 ccagtcctca ttctatcaca tcttcacttt tttgatgatg caaattttta ttttggtttc
    27841 tatatatgaa tctaaatttt tgacagcgtt tcctaaataa gagatgatag acgaacaaaa
    27901 cagaaaggag acgaaacaaa tgaatagtat ggtttttgtt aattttcctg ttgctgatgt
    27961 caatcgttcc gttgcttttt atgaaaagct gggttttaaa aaaaatgaag aattttctac
    28021 tgaagaagct ggttcaatgg tatgggatga cactttttgg ataatgcttc tctctcatga
    28081 tttttataaa aaatttataa aagataaaga aatagctgat aataaaaaaa caagtggtgc
    28141 tttgatttcg tttagtgttg aaaatgcgga tgaagtaaaa aaatttgctc aaattgcaaa
    28201 agaaaatggt ggtactttcc acgaagtaga tatgggaatg cctgaagaag aaatgttttc
    28261 attagaagtc caagatctag acggaaatac attagaaccc gtatggatga agatgtaagc
    28321 agataactaa tctgacgttt tttataacaa aaaaacaaag gcggatgata cgataagtat
    28381 tctccgcctc tatttttttt attcgtacaa tctctttttt acagtttata aaagcagtct
    28441 tctcaccctt tttttaattg ttagatgcca gtgtatgtaa atcaccaatg tgtcatgaca
    28501 cattggtgat tttatggtat ccttttatta ttaactgaca aaggagagaa tattttgaac
    28561 actttgattg caaaagacgt ttttagattg cccgaaatga atgcaagatt gttgtcgacc
    28621 tctgctcttt tattagccct tgatgtcatc ttatacaaga tagcgattgg tcctgcttat
    28681 tttcaaatca cattcggatt tttaagtatg gcgcttatgg gttatctata tggaccgatc
    28741 tgggctggtt tgcttgaaat gttgtcgaac actttaaatt tcacgatatt tggttcagga
    28801 acgtttcaag ctgcttttct tatcacggct ttccttggtg gatttattaa tggcttattt
    28861 ttatatcata aaaagataaa cctgccttcc gtcatcgctg cccaattatt gattatgatc
    28921 ccagtcagcc tttttatcaa ttcttggctg atgtctgttt tgtttggtgc agatttcaaa
    28981 gtaatttttc taggtagatt catcaggaat atgatccaaa tccctattca aataatggtt
    29041 gtttattcat ttatcaaaac tttagaggct agaaaagtgt ttaaacgagc tgtttgattt
    29101 tacgtactaa ggtagtaaac tgattttgga ttaaacaata aagcgtgcag tctcaacaga
    29161 ctgcacgctt tattgtttct cactggatcc attttatttc atcaagtgga taatagacaa
    29221 atcttgcttt acctagaata tcagttttat tgatcgtgcc aaacgaacga ctatcttttg
    29281 aaactcttcg attatctcca agtacaaaat aattatcttc cggaagcttg gattgtcccg
    29341 ttagctcttg tagtgtaaag tccgtcgtat aggatgcatt tgcatgatct gatttcaggt
    29401 ttttagttag ataaggttcc ttaactactt tcccattgat cttcaattga tcattttggt
    29461 agctgacatt ttctcctgga agaccgatta ctcgtttgat ataaatcgtg ccatctgcta
    29521 attgaaaaac aacaatatca aatcgtctga tctccgaaaa tttttccatc acaaccatat
    29581 caccttgctt caacacgttt tccattgaat tgccttccac tggtaccggg atgaataaaa
    29641 atccccgcaa catgaacgca aggaatacag aaacaagtaa gtatttgaat acaagccaga
    29701 agcgattaat atagcgttgt ttttttgtca atctctatca atccatccct ctttttttca
    29761 ttctttcttt attataagaa aaatatcaaa aaaa
//
LOCUS       DAZAOD010000022        29418 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000022 DAZAOD010000000
VERSION     DAZAOD010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.023"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            129..785
                     /locus_tag="ACHDPO_001063"
     CDS             129..785
                     /locus_tag="ACHDPO_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFN3368706.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(1227..2024)
                     /locus_tag="ACHDPO_001064"
     CDS             complement(1227..2024)
                     /locus_tag="ACHDPO_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFN3368707.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(2021..3205)
                     /locus_tag="ACHDPO_001065"
     CDS             complement(2021..3205)
                     /locus_tag="ACHDPO_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFN3368708.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(3230..4477)
                     /locus_tag="ACHDPO_001066"
     CDS             complement(3230..4477)
                     /locus_tag="ACHDPO_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFN3368709.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            4692..6437
                     /gene="dnaX"
                     /locus_tag="ACHDPO_001067"
     CDS             4692..6437
                     /gene="dnaX"
                     /locus_tag="ACHDPO_001067"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFN3368710.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            6457..6771
                     /locus_tag="ACHDPO_001068"
     CDS             6457..6771
                     /locus_tag="ACHDPO_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFN3368711.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            6796..7392
                     /gene="recR"
                     /locus_tag="ACHDPO_001069"
     CDS             6796..7392
                     /gene="recR"
                     /locus_tag="ACHDPO_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFN3368712.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            7456..8100
                     /gene="tmk"
                     /locus_tag="ACHDPO_001070"
     CDS             7456..8100
                     /gene="tmk"
                     /locus_tag="ACHDPO_001070"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFN3368713.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            8115..8444
                     /locus_tag="ACHDPO_001071"
     CDS             8115..8444
                     /locus_tag="ACHDPO_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFN3368714.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            8458..9396
                     /gene="holB"
                     /locus_tag="ACHDPO_001072"
     CDS             8458..9396
                     /gene="holB"
                     /locus_tag="ACHDPO_001072"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFN3368715.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            9432..10256
                     /locus_tag="ACHDPO_001073"
     CDS             9432..10256
                     /locus_tag="ACHDPO_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFN3368716.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            10249..10596
                     /locus_tag="ACHDPO_001074"
     CDS             10249..10596
                     /locus_tag="ACHDPO_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFN3368717.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            10665..11537
                     /gene="rsmI"
                     /locus_tag="ACHDPO_001075"
     CDS             10665..11537
                     /gene="rsmI"
                     /locus_tag="ACHDPO_001075"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFN3368718.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            11646..12767
                     /gene="dinB"
                     /locus_tag="ACHDPO_001076"
     CDS             11646..12767
                     /gene="dinB"
                     /locus_tag="ACHDPO_001076"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFN3368719.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(12821..13423)
                     /gene="nrdG"
                     /locus_tag="ACHDPO_001077"
     CDS             complement(12821..13423)
                     /gene="nrdG"
                     /locus_tag="ACHDPO_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFN3368720.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(13738..15927)
                     /gene="nrdD"
                     /locus_tag="ACHDPO_001078"
     CDS             complement(13738..15927)
                     /gene="nrdD"
                     /locus_tag="ACHDPO_001078"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFN3368721.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            16253..17020
                     /locus_tag="ACHDPO_001079"
     CDS             16253..17020
                     /locus_tag="ACHDPO_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368722.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            17010..19052
                     /locus_tag="ACHDPO_001080"
     CDS             17010..19052
                     /locus_tag="ACHDPO_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368723.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            19333..19482
                     /locus_tag="ACHDPO_001081"
     CDS             19333..19482
                     /locus_tag="ACHDPO_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFN3368724.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            19493..21007
                     /gene="dltA"
                     /locus_tag="ACHDPO_001082"
     CDS             19493..21007
                     /gene="dltA"
                     /locus_tag="ACHDPO_001082"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFN3368725.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            21004..22209
                     /gene="dltB"
                     /locus_tag="ACHDPO_001083"
     CDS             21004..22209
                     /gene="dltB"
                     /locus_tag="ACHDPO_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFN3368726.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            22254..22487
                     /gene="dltC"
                     /locus_tag="ACHDPO_001084"
     CDS             22254..22487
                     /gene="dltC"
                     /locus_tag="ACHDPO_001084"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFN3368727.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            22490..23758
                     /gene="dltD"
                     /locus_tag="ACHDPO_001085"
     CDS             22490..23758
                     /gene="dltD"
                     /locus_tag="ACHDPO_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFN3368728.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            23899..24981
                     /locus_tag="ACHDPO_001086"
     CDS             23899..24981
                     /locus_tag="ACHDPO_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFN3368729.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            24981..25784
                     /locus_tag="ACHDPO_001087"
     CDS             24981..25784
                     /locus_tag="ACHDPO_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFN3368730.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            25854..26594
                     /locus_tag="ACHDPO_001088"
     CDS             25854..26594
                     /locus_tag="ACHDPO_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFN3368731.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            26605..27609
                     /locus_tag="ACHDPO_001089"
     CDS             26605..27609
                     /locus_tag="ACHDPO_001089"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFN3368732.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(27654..29417)
                     /locus_tag="ACHDPO_001090"
     CDS             complement(27654..29417)
                     /locus_tag="ACHDPO_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368733.1"
                     /translation="MLFLTGIAYFFYFIFSPADSNQMKEIKDSWVFYTKDDPDFKFDS
                     KYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEES
                     NPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQV
                     LTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCFALALGFEAVSEDILSGILFEP
                     FVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAEL
                     PELMPIANIASVISTLVTSLACIGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGI
                     YQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQH
                     IQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLI
                     LARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLIHALEHSFRETHAIENPLYRKI
                     YLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQ
                     EKDTFIDRITVQLSRNYPNPV"
BASE COUNT         9298 a         5180 c         6059 g         8881 t
ORIGIN      
        1 aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag taaaatacct
       61 ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt ttggatgggg
      121 gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat tttccgatta
      181 tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc catacgtata
      241 tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga gaatttaacc
      301 ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat tcacaattca
      361 tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat cgaatcaatc
      421 gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat gtaaaagagt
      481 attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta ttaaacggaa
      541 agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt gtgcggacag
      601 aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa ttttgtggca
      661 tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat ggtattatca
      721 ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac aatattatct
      781 tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga gaaacaaacg
      841 gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc agctgattga
      901 acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa ggaacaattt
      961 caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga gttggtagga
     1021 gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat aagaagagcc
     1081 aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta gatgtaagct
     1141 tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc acagcccttt
     1201 ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc aaaagtcccg
     1261 ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg gcttttgggg
     1321 attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt taatttgata
     1381 ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata acgcgaaaca
     1441 gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat gatgatttct
     1501 actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac acgataatgt
     1561 cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc ttttgcagca
     1621 ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga atcgattctg
     1681 ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc acgctgtccc
     1741 atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct taagtaatta
     1801 tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa gactcgtcct
     1861 ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg atctgttgtg
     1921 aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac cggccagcca
     1981 acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag taacctccga
     2041 tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc aattttttct
     2101 ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg tagtagtaga
     2161 cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt aatacgtaat
     2221 tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt gtatatccat
     2281 ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga atctgtgatt
     2341 tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa tactggcttt
     2401 taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc ttttgttgcg
     2461 tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct gctcttgaaa
     2521 cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg cggataactg
     2581 taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa gggaaataca
     2641 cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca aaccattttt
     2701 tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca aaaggaagta
     2761 ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga ttatggcagt
     2821 agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca cagttgggac
     2881 aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta tctgaaaaac
     2941 cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc tgttcttggg
     3001 ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg ccagccatac
     3061 gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag atattcaggc
     3121 agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg ccgcaattag
     3181 gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat taattaacgg
     3241 ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg ttggaaagat
     3301 ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg ttttctacag
     3361 gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg caaactggac
     3421 atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct gcttgttgtt
     3481 tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt gcattcattc
     3541 ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg gctgcttcca
     3601 taccacgtgc aatggaacct tgcacgtagc cttcacgtac gctaggatca cctagcatcg
     3661 ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa atgctggcta
     3721 cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc aatgcagtat
     3781 ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt tgaccatctg
     3841 cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa tactgctcat
     3901 tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta taaaataaaa
     3961 tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat tctgcgttat
     4021 agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc tttatttctt
     4081 ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat ttgaatcggt
     4141 caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga gctgcgtcat
     4201 ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca ccatcgacca
     4261 aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa acatcttctg
     4321 ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct tttgtcatga
     4381 ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct gccagaccgc
     4441 cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc tctgattcag
     4501 ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa acttctcgga
     4561 ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa aagccgagaa
     4621 ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt ttttaaaaaa
     4681 gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag cgtttcgaag
     4741 acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt tcccacaaaa
     4801 cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt gcagcaaaga
     4861 ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc aacgaatgcg
     4921 aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc gatgctgcca
     4981 gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat gcgcctacaa
     5041 aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca ggagctttca
     5101 atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc ttagcaacga
     5161 ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt gattttaaac
     5221 ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa tcgactatca
     5281 gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg atgcgggatg
     5341 cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact ttagatgatg
     5401 ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg agtgcttgcg
     5461 tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca gccggcaaag
     5521 aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg atgtatcagc
     5581 aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt acagaattgg
     5641 cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc gatactcaaa
     5701 atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca gtcaaacttg
     5761 cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat gatcagatag
     5821 taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa ctacgcagta
     5881 atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat aaaaaacaga
     5941 caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa gcgacaagac
     6001 agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta tctgtcactc
     6061 agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga ctagtgattg
     6121 cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg cagctttcgg
     6181 tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt tatattacaa
     6241 gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa gagggaacag
     6301 aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct caagaacaag
     6361 aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc gaagctgtta
     6421 cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat gggcaatatg
     6481 caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc acaagagctg
     6541 ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc ggtttttaca
     6601 ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc tgatgatatc
     6661 gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca aattgatgtg
     6721 gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta gttttaaact
     6781 gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga cagctacatg
     6841 aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac gatcgatatg
     6901 aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg cgatttgcat
     6961 ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg tagaaatcct
     7021 tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat ggcaatggaa
     7081 aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc accgatggaa
     7141 gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca tgatgcagat
     7201 gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac agctatgtat
     7261 ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca tggtctgtct
     7321 gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt cgaaggaaga
     7381 cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag cagcacaaga
     7441 gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga tggtgcagga
     7501 aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa aacagaaatc
     7561 attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc agtgatcctt
     7621 gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc agcagcaaga
     7681 agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat cgttttatgc
     7741 gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat cggcgttacc
     7801 gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt taccctttat
     7861 cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca aaatcaaatc
     7921 gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc ttacttaaag
     7981 ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag ctttgaagaa
     8041 gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt tgaaaactag
     8101 gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac agcaaccgtt
     8161 tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg acaggcggct
     8221 tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt gtagaagaag
     8281 cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct acacctgtta
     8341 cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa gtaggcggtg
     8401 ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag ctgagctatg
     8461 aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct tcaacggagt
     8521 tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg aacaggaaaa
     8581 catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa agacaatctg
     8641 ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc agatgttttg
     8701 gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt gcagacggaa
     8761 ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga agctgaaaaa
     8821 atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc tggagatttt
     8881 ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca atctcgttgt
     8941 caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt gcaagaagag
     9001 cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt aggaaaagca
     9061 gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta tcaatggttc
     9121 gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa attggtaaaa
     9181 tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt ttattatcag
     9241 gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca gataaaccag
     9301 ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag ttttcaggct
     9361 gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga tgatgatcaa
     9421 ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt catatctatt
     9481 attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc gaatctcagc
     9541 aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc aatgaccttc
     9601 ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa aaagacaaaa
     9661 aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg cagttgcgtg
     9721 agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa ttgatttttt
     9781 ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg gccgctgtat
     9841 ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag ataataggcg
     9901 gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat ttcgtgcctg
     9961 tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa atttccggtt
    10021 tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag acagcgaaaa
    10081 aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg aaagtcgtag
    10141 ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa aatcctgtcg
    10201 aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat ggataagaga
    10261 tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt aacagaactt
    10321 gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt ggagatggaa
    10381 aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc tccagctgaa
    10441 aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta tgaagaagga
    10501 ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc ttgtgcgttt
    10561 tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg agactggagc
    10621 ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat aatcaaaaaa
    10681 gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca attggaaatt
    10741 tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt atcgcaagtg
    10801 aggatacgcg taatacacaa aagttattga atcattttga aatccataca ccccaaaaaa
    10861 gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg ttaaaagaag
    10921 gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat cctggacatg
    10981 agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca ggacctacag
    11041 ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta ttttatggct
    11101 tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa gaacagacag
    11161 ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg aatttcttag
    11221 aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc catgaagaat
    11281 accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca gtaaagggtg
    11341 aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa gttgatgaag
    11401 agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa aaaccaaatg
    11461 ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc taccgtcagt
    11521 accatgaatt agactgagat agtataagtt gtctataatg aaagactaat gaggaaatca
    11581 gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat gaataagagg
    11641 tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa atcattcata
    11701 ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag tttcgcggac
    11761 atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta gtgactacag
    11821 caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa aaagcgtatg
    11881 agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc gatatttcca
    11941 aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt agtatcgatg
    12001 aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc aaaatcgccc
    12061 gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg ggagtaagtt
    12121 acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga atcacggtag
    12181 ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa tttcatgggg
    12241 tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga aaagacctat
    12301 atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat tctctttatc
    12361 gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga aaatctgtgg
    12421 gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg actcagttgc
    12481 gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat gggaaaacag
    12541 tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg acattgccag
    12601 aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg gaggaaatct
    12661 tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg gacccgatga
    12721 cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa cagctttgag
    12781 agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag tcttgctttt
    12841 tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca acttgattgg
    12901 attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga aattgtagtt
    12961 ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt tgcgaaagga
    13021 gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct gtccatgacc
    13081 agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc agacaaacat
    13141 ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa tcgttgcgca
    13201 agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat cgaaaatttt
    13261 gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg taaagactgt
    13321 tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata tagttttggc
    13381 tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa cttctttcat
    13441 ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata aataagaaca
    13501 aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag ggcgttcaaa
    13561 gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc ttattctgaa
    13621 taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga aaaatatgag
    13681 gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt cacaacctca
    13741 tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca tcggacgagc
    13801 ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt ttggatcatg
    13861 atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac cttcgaaacc
    13921 acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt tgtcatatgc
    13981 aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt attcacagta
    14041 gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca atttttcaaa
    14101 tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt ctttatctgt
    14161 gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt cagttagact
    14221 ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc atgcatctgc
    14281 attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg ggtttgtttc
    14341 ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc ctaacgatac
    14401 agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa gacgtttccc
    14461 gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt tacaacgttc
    14521 tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta actgccagaa
    14581 tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg taacaacacc
    14641 taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc cttgcaagaa
    14701 tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt tatcgtaatt
    14761 cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt tgatgtcgta
    14821 attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca gtttagggaa
    14881 gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa ttgctttttg
    14941 aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga aaggagtttg
    15001 tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag catcgaagat
    15061 atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat cgatccattc
    15121 ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa gcaattcatc
    15181 tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa taatctgtga
    15241 gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat tgccgatttt
    15301 gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca tcggtgtata
    15361 aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat ttgctatatg
    15421 tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca gatctcgctg
    15481 tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt ggtccttgtt
    15541 gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa aatctcgttt
    15601 ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta gtaatatatg
    15661 ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc ttttgatttc
    15721 ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg ataatgagcc
    15781 gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat cgaaatcaac
    15841 atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct gagtaacgac
    15901 agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg ttcttgtcta
    15961 tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt attcaatgtg
    16021 ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa aaaggtgaaa
    16081 acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa ataattgaat
    16141 aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat tattcgtaga
    16201 tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag aattggaaaa
    16261 gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc ccgtcaaagc
    16321 cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta tgggcccaag
    16381 tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc ctacgatggg
    16441 cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc tcagtgactt
    16501 tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata ccctaaatgc
    16561 aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg aaatggaaaa
    16621 gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac ggtatcccga
    16681 tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg ttgttcagcc
    16741 acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg ctacagaatt
    16801 gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt tagtcaccca
    16861 tgatccatat acagcaagct actgcgatag aattttattt attaaagatg gtgtgatttt
    16921 ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa tagacatgca
    16981 ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt aaaagttttt
    17041 ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc gtaatgatct
    17101 attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca agtcaagata
    17161 cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt ttgctttttt
    17221 tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata ggcatctatc
    17281 agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa atcatgataa
    17341 ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc aaactctttt
    17401 caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt atctccattc
    17461 catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta tctgtatatt
    17521 caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa gaacaagcag
    17581 atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc gggttactac
    17641 ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca tggatgatca
    17701 gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt ttcgtttgtg
    17761 tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc atattgagta
    17821 aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg caagttcatt
    17881 tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt tctttaatga
    17941 caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa gtttcctccc
    18001 cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt ctagcagagg
    18061 aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg agtatctata
    18121 gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa acacaatatc
    18181 aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca cctggtcata
    18241 ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat ggatctagta
    18301 ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt gtattaggtg
    18361 acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt tttgaaaaag
    18421 caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat aatgaaaaaa
    18481 tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt tattattctt
    18541 atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt ccggatgacc
    18601 aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct tccagctatt
    18661 cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca ctatttgtcg
    18721 ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta gcagaagcag
    18781 aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa agaaggatca
    18841 gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata ttagggatca
    18901 ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc gattactggt
    18961 tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat gtcattacga
    19021 gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag ataataaata
    19081 gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat ttttgtcaca
    19141 acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa aagcagtgat
    19201 ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa acggtttctg
    19261 taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga ggttatatga
    19321 ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg gggaaaattc
    19381 atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct gtatcactat
    19441 aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga gtatggaaat
    19501 caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc gagttgctta
    19561 tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg cacttgctta
    19621 ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca atttggagtt
    19681 tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt tgccgattga
    19741 agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac catctatggt
    19801 catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa caaaaaaaga
    19861 atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg taaaaggtac
    19921 agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag gcgtacaaat
    19981 cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg ggatcaagcc
    20041 tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat tttctattta
    20101 tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg ttcaagactt
    20161 tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt ctactccatc
    20221 atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc cggaattgga
    20281 catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc tacttgatcg
    20341 attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg tagctatttc
    20401 aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga ttggctacgt
    20461 aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa aaggagaaac
    20521 gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca atcccgaaaa
    20581 gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag gggatgcagg
    20641 tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc aggtcaaatt
    20701 acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag acaaccgaat
    20761 caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc tggttgcttt
    20821 tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat ctatcaaaga
    20881 acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt atgtcgatct
    20941 gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg aggtgaatcc
    21001 tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt tcttttagcc
    21061 attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt accagtttat
    21121 caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta ttggcaacag
    21181 ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg ctattttgtt
    21241 tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt agcgataatt
    21301 ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc gttacttggt
    21361 tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga aataagagat
    21421 ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt ctttccaaca
    21481 atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct ccatccgcct
    21541 gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt tgtcggtttt
    21601 ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt agtgggacgc
    21661 attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta cgtgtacagt
    21721 atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac aagctacatg
    21781 atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa tatcaaagaa
    21841 ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt atatatgcga
    21901 ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat gtcaaatatc
    21961 ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg gtactacatc
    22021 gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat ccgatttaag
    22081 aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc cgtatttttg
    22141 acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga taaacttttt
    22201 tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg aaaatggaag
    22261 aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga aaaaatcgtg
    22321 atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa ttattagtcg
    22381 agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga gaggattggt
    22441 gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta tgaaaaagaa
    22501 actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg tgttttttac
    22561 ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct cttcttccat
    22621 gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg aaaaacaata
    22681 tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc cgtctgttct
    22741 ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg ggacacaatc
    22801 gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca agaaagtcgt
    22861 ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt actttaatac
    22921 gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag taacgcctgc
    22981 tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga atgatacgtt
    23041 gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat ctttgaatca
    23101 gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca atattgggtt
    23161 gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac aataccaaga
    23221 aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga ataatccatt
    23281 cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag agctcaaaca
    23341 gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc agctggtctt
    23401 ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg ttaacgagaa
    23461 atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca aaaagatcaa
    23521 atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc aagcgggtac
    23581 caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg ctgcagatca
    23641 acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc atcttgacga
    23701 tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat taaaataaag
    23761 aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga ataaaagata
    23821 aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca atatgaatat
    23881 agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga tttaacttct
    23941 gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga atatgccaaa
    24001 ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa acatggtgct
    24061 ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt tatggtaaca
    24121 aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg ggggcaagtc
    24181 atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca cggtgtgatt
    24241 ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta tgaaataaag
    24301 gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg gggcatacgt
    24361 cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag taaatattta
    24421 ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt attagagaat
    24481 ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca agaagaagta
    24541 ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc ttttgcttta
    24601 gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga ttcgatttta
    24661 ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa aaaattattg
    24721 aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac agtgatttct
    24781 ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc gtctgtagcc
    24841 attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga agatgattat
    24901 ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga aacagttgaa
    24961 aaaattcgga gttatgaata atgaataata gaatacctat ttctgaatat cggaaaaaag
    25021 cacgagtttc tttggaaaat caatggggaa tcaatacttg gcttgttttc ttatctataa
    25081 tatttacgag cgtcatccag aacttttttg acggtttcag tccttttccg gaagaaagca
    25141 tgcagcagca cttattgagt tttctagtcg ataatttact tttattcgca ttcaactatg
    25201 cattgtttta cattgcgcta gtagttgtac ggggtggcag accaaaaagt aaccttttat
    25261 tttcagtttt ccaaagaaag tattttggtt cgatacttgg catcaatttg atcaattcag
    25321 tcatcaactg gctactcaac agtttaatct ttctgcccat gtttttaatc agcggagtga
    25381 gtacttatat gcagctgctt ttcagttcaa atgcggtacc tacgggtgtc atgccagaag
    25441 attttcttga tatcagcttt gttttatcga tgatagggat gatttttgtt tcagcactca
    25501 tcatgagtat tgttggcggt ttattccaat ttgctgcatg gacaaagttc gactatcctg
    25561 atttgtcggt tattcaatgt ttgaaatatg gctggttttt attgaaagat agaattggta
    25621 cgtatatttt gttgcagctg tcttttatcg gctggtattt gctaggagca atcgctttgt
    25681 tcatcggtct tttgtgggtc attgtttatg tgaatgtgtc agttgcagaa ttttatgaac
    25741 aagcacggat tgaaaaagga ggtccagacg cctattttac ttagcatgta agcagtttat
    25801 tcatcaaaaa aataactttt gtggtaggat aaatctttga gggggaatgt acgatgaaat
    25861 taactgtttt aggatgctta ggagcgtatc cttataaaaa tcaagggaca acaggttatt
    25921 tgcttcaatc tgacgggttc aatttgttga tcgatgcagg tagtgctacg ctgatcaaat
    25981 tacaagaaca ccttgatcca cttgatctag atgctgtgat ccttagccat tatcatcatg
    26041 atcatattgc tgaccttggt gtattacagt attactggca acttcatcct aagagaaatc
    26101 cggagacatt gctttcaatt tatggacaca caaaagattc cattcacttt gaagaattga
    26161 cgttggaaaa tgtctcaaaa ggacatcctt attttgaagc tgaagaatta aaaattggtc
    26221 cttttctgat tacttttatg gaaacaatcc atccagtagt atgttacgcc atgcgtatcg
    26281 tagaagaaac aacggggaaa gtattcgtat ttacaggtga ttcaggttat ttggaaagtt
    26341 tcgctgattt tgcgaaagat gctgatttgt ttctagcaga tacctatctt tttgaaggaa
    26401 atgaacatca tcatgcccat ttcacttcaa aagaagctgg agaacttgcg aaatcagcta
    26461 acgtaaagaa acttgtactt acacacctac ctcagtttgg tgatttagaa caattgaaaa
    26521 atgaagcgca aaaggcagca ggcaaaggga ttgatataga acttgctgca gttgacaaag
    26581 tgtttaacat ttaggaggaa gaacatgatt tttgtaccaa atgaaaacca cgacccaaga
    26641 atcaatttag caattgaaca atatttgctg caagaaatgc ctttagatga acctattttg
    26701 ctcttttata tcaatgaacc ttcaatcatc atcggcagaa accaaaatac gcttgaagaa
    26761 atcaatcgag attatgtgga agaaaatggc attcatgttg tccgtcgctt aagtggaggc
    26821 ggagctgtct accatgattt tggaaacctg aactttagtt ttatcatgcc tgatgatggg
    26881 gattcattcc gtgactttgc gaaagtaaca cagccaatca tccaagcact tcatgaattg
    26941 ggtgttgctg gggcggaatt gaaaggccga aatgatctag tcattgatgg catgaaattt
    27001 tctggcaacg cgatgtatgc taccaacggt cggatgtttg ctcatggaac aattatgttc
    27061 gactctgata tcaatgaagt agtcaatgca ttaaaagtaa aaaaagacaa aatcgaatca
    27121 aaaggaatca aatcgatccg ttctcgtgta acgaatatca aaccatttct tccagaagaa
    27181 aagcaaaaaa tgacaacaga agaatttcgt caagaaatct tgttgaaaat tttcggcgta
    27241 gagtcagtag aagaagtaaa aacgtacgaa ttgactgatg aagattggaa aaaaatcaat
    27301 cgaatctctg aggaatatta tcgaaattgg gattggaatt acgggaagtc tccagatttc
    27361 aatttctctc gccaaaaacg tttttctatc ggttcgattg aagtccattt gaatgtctca
    27421 gaaggaatga tcaaagaagc aaaaatcttt ggcgatttct tcggactagg agatatctct
    27481 gacgtggaaa aaaaattggt tggacagaaa tatgataaag catctctatc aaaaatagtc
    27541 agccaaattg atgtgaagaa atattttggt gcgatagaac cagaagaatt gcttacctta
    27601 ctttattgaa aataaaaaat agcggaatcc acatatatgg attccgctat tttttataca
    27661 ggattcgggt aatttcgaga gagttgaaca gtgatccgat caatgaaagt atctttttcc
    27721 tgcgttagtg ttcctgtgta acgatccgct acgtctttca tcatcattaa gtcaaaacgt
    27781 tcctgatcat ctaattcttc tgtgatgcct cgactaaata ggtttgtatc gtaatgtgca
    27841 ctatgttcgc aacaaatgac gaaatgttcc tcttgttcgt gtatcgacaa ataaattttt
    27901 cgatacagtg gattttcgat ggcatgagtt tctctaaagg aatgctctaa agcgtggatc
    27961 aaaagttgag ccagatcgtc atcgttgata ggaagttctt cgggaagatc tgcttggaag
    28021 gttatctgaa tattccgttt ggcagctaac ttctggtaac gcgctaagat aagatttgtc
    28081 acctggtggt tgcaaaaaga acacagcatt tcgaaatttt ttgcttcttc taatatcttt
    28141 tccacatagt ttttagcttt tgtttggtcc gtatgcatta aatcttgcag attctccatc
    28201 tcttggacaa attccaggcg aagtgtattt acttcttgga tatgctgtcg aagctgctca
    28261 taatgttgct ccaacaaatc atttttgatt tttaagaaat ctacttgtct ccgatctttg
    28321 tcggtattta agatgtgatc gattagattg tagctgataa taacgattag aatgataata
    28381 tataaaatcg tagaccaatt gatcgttgtt tgatagatac ctaatgccgt ttggatgtaa
    28441 atcaagcaat ggataatggc taccaagacg atccaaggtg tacaagctac ataaaaacgg
    28501 ttattcttat atgcttcgcc aatgcatgca agtgaagtga ctaaagtgct tataacacta
    28561 gcaatattag caatcggcat taattcagga agttctgcag gagtaaaagt tgcataaagc
    28621 agaacgccga taaaaatcaa aagttggaac gtacaaaaaa ttccgtacca ttttttatag
    28681 taaaacattc ggctccaata gtagcagatg atgaaagctg acgttaagat aataaataaa
    28741 tgagataaaa aagaatgaac gaatggttca aaaagaatac cacttaaaat atcttctgat
    28801 acagcttcaa atcctaatgc caaagcaaag caacttaaga gaataagtga gtattcaaga
    28861 cgtttttgtt tatacatcaa gtagatcgta tagaaaaagg tccctatagc gataaaaaca
    28921 gcgattatca tcgtcaatac ttgcggcact gattgtgaat aaataaaact aatcaatggt
    28981 ccagttgttc ctagataaac tttcggtggc agtccagcat agttctgata aggagatgag
    29041 actgtaaggg tcaatttttt tccgatataa tttgctggta aatctatcac agccaatgag
    29101 agtccgggat tgctttcttc ctgataatct ttccgttggt ataaaatctt ttcgcctaga
    29161 tatacagtaa tccattgatg gtttcctttg attagtaaat ttgcttcgtc caacggtttt
    29221 tcaagtgtcg tttccataat gaatgtttcg tctttatcca cggtaggaat cgtacgagtg
    29281 tacttgctgt caaacttaaa atcaggatca tcttttgtat agaaaaccca cgaatctttt
    29341 atttctttca tttgattgct gtccgcagga gaaaaaataa aataaaagaa ataagcaatt
    29401 cctgttaaaa ataacaat
//
LOCUS       DAZAOD010000023        29362 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000023 DAZAOD010000000
VERSION     DAZAOD010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.024"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(482..985)
                     /locus_tag="ACHDPO_001091"
     CDS             complement(482..985)
                     /locus_tag="ACHDPO_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFN3368734.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1344..2369
                     /locus_tag="ACHDPO_001092"
     CDS             1344..2369
                     /locus_tag="ACHDPO_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFN3368735.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2692..3570
                     /locus_tag="ACHDPO_001093"
                     /pseudo
     CDS             2692..3570
                     /locus_tag="ACHDPO_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
     gene            4046..4162
                     /locus_tag="ACHDPO_001094"
     CDS             4046..4162
                     /locus_tag="ACHDPO_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFN3368736.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            5090..5428
                     /locus_tag="ACHDPO_001095"
     CDS             5090..5428
                     /locus_tag="ACHDPO_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368737.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5522..5752
                     /locus_tag="ACHDPO_001096"
     CDS             5522..5752
                     /locus_tag="ACHDPO_001096"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFN3368738.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            6152..6523
                     /locus_tag="ACHDPO_001097"
     CDS             6152..6523
                     /locus_tag="ACHDPO_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFN3368739.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(6797..7489)
                     /locus_tag="ACHDPO_001098"
     CDS             complement(6797..7489)
                     /locus_tag="ACHDPO_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFN3368740.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7492..8277)
                     /locus_tag="ACHDPO_001099"
     CDS             complement(7492..8277)
                     /locus_tag="ACHDPO_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFN3368741.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            8514..9914
                     /gene="lacG"
                     /locus_tag="ACHDPO_001100"
     CDS             8514..9914
                     /gene="lacG"
                     /locus_tag="ACHDPO_001100"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFN3368742.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            9939..10256
                     /locus_tag="ACHDPO_001101"
     CDS             9939..10256
                     /locus_tag="ACHDPO_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFN3368743.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            10269..11942
                     /locus_tag="ACHDPO_001102"
     CDS             10269..11942
                     /locus_tag="ACHDPO_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFN3368744.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            11956..13587
                     /locus_tag="ACHDPO_001103"
     CDS             11956..13587
                     /locus_tag="ACHDPO_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFN3368745.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(14078..15643)
                     /gene="guaA"
                     /locus_tag="ACHDPO_001104"
     CDS             complement(14078..15643)
                     /gene="guaA"
                     /locus_tag="ACHDPO_001104"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFN3368746.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(15702..16625)
                     /gene="coaA"
                     /locus_tag="ACHDPO_001105"
     CDS             complement(15702..16625)
                     /gene="coaA"
                     /locus_tag="ACHDPO_001105"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFN3368747.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            16821..17426
                     /locus_tag="ACHDPO_001106"
     CDS             16821..17426
                     /locus_tag="ACHDPO_001106"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFN3368748.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            17734..18750
                     /locus_tag="ACHDPO_001107"
     CDS             17734..18750
                     /locus_tag="ACHDPO_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3368749.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            18891..20192
                     /locus_tag="ACHDPO_001108"
     CDS             18891..20192
                     /locus_tag="ACHDPO_001108"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFN3368750.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            20238..20900
                     /gene="deoC"
                     /locus_tag="ACHDPO_001109"
     CDS             20238..20900
                     /gene="deoC"
                     /locus_tag="ACHDPO_001109"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFN3368751.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            20921..21319
                     /locus_tag="ACHDPO_001110"
     CDS             20921..21319
                     /locus_tag="ACHDPO_001110"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFN3368752.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            21385..22467
                     /locus_tag="ACHDPO_001111"
     CDS             21385..22467
                     /locus_tag="ACHDPO_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFN3368753.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            22679..24241
                     /locus_tag="ACHDPO_001112"
     CDS             22679..24241
                     /locus_tag="ACHDPO_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368754.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            24234..25367
                     /locus_tag="ACHDPO_001113"
     CDS             24234..25367
                     /locus_tag="ACHDPO_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368755.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            25367..26323
                     /locus_tag="ACHDPO_001114"
     CDS             25367..26323
                     /locus_tag="ACHDPO_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368756.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            26422..27588
                     /gene="deoB"
                     /locus_tag="ACHDPO_001115"
     CDS             26422..27588
                     /gene="deoB"
                     /locus_tag="ACHDPO_001115"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFN3368757.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            27612..28430
                     /locus_tag="ACHDPO_001116"
     CDS             27612..28430
                     /locus_tag="ACHDPO_001116"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFN3368758.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            28447..29154
                     /gene="deoD"
                     /locus_tag="ACHDPO_001117"
     CDS             28447..29154
                     /gene="deoD"
                     /locus_tag="ACHDPO_001117"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFN3368759.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         9236 a         5113 c         6321 g         8692 t
ORIGIN      
        1 aaataacgac acagaaaata ccgtgtctca gatttctcta ctacttctaa aaactactgt
       61 ttttttcctt tgaaatgcct tcaaaaagta ggatcaggca gaatatactg gcagaatcaa
      121 ggagaaggga gcctaaataa ggagaaaaac catagaaaat ataaagtaat tacttataaa
      181 acaagctttt tatagaaaaa taatatacct gagtagggta taaattaaga cggaattcct
      241 ttctagattg agatattgac taggaagaat gttaagattt taagccttta agctaaaaaa
      301 aaaccctttt tgttaaataa ggggaatata gcctgtcagt ttcaaactgc aagtcgtcct
      361 gctgcaataa tatagtagat tagagatgaa aatagatttt tttaaaccaa tgactgaata
      421 aaaagaccgt catagataca cattggaatg tgtctattac ggtctttttt tacgaacgat
      481 tttattgaag acggacagtt cgggtcaaaa ataaaaaagc tacgatcaga aataagaata
      541 aaatgtatcc caaaataatg gctagacggt ctaacttatt tgtcgataga tgtttgttta
      601 gaagttgata ggcccataaa cctatcagtc ctcctgttgt attagttatc aaatcagtga
      661 tgtccgctac gccaataccg aataggaatt gaatcaattc tgccaagaag cttacaagga
      721 aaataatccc taatttttta gaaaaagaaa gtctcttgaa attgacattc aaaagcaccc
      781 caaaaggaaa aaagacaatc aagttataag tggtctcacg taataccgtc gtattttcaa
      841 aagaaaaagt agaaaaaggg acgagattga cattgctgta agaataagtg agaaattgtg
      901 gaagattaaa tgatagcttg aataaaatca accataatag aaagaataaa taaatcccta
      961 ataaaaattt tgatacatac cgcatagaca tctcctccat ttaaaaagta taccatcgaa
     1021 aaccgctgaa aaatcataaa aaagtatgaa gtttaaggac caacgtagtt atcgtacgaa
     1081 aattagaagc ttttttttgt tgggaatccg gtttctttaa caaagctaag atagcgagtt
     1141 gcttggaaaa gttgctatct tttttctgtc aaaacgactc ggaatgttcg ttttttgttc
     1201 taatttctcc aagttgttta ctttttgata ctaagtttat gaaaaatcaa gaaatagttg
     1261 ttatactagg taatgctgac aaacgggatt ggcatttcat cttggttcag ctttttttcc
     1321 aattactagg aaggagggat agattgttca agacttattt tcgtttcaat aaaatacaag
     1381 ataatccttt tcgtatcatg aatctgatgc tacttatctt tattgtatta tggttaggtt
     1441 acataaatca tgattttttg atttcaagtt tttcatcatt agggatcttt acttttttct
     1501 attatcaaaa cataccgatg aaatatttgc tgaaacgtat gtttctgatc ggttgcggac
     1561 tgttggttgc tttcgttttg gggatcttat cgacttatgt tttatggctt gaaccatttg
     1621 ccgtagcttt ggttgctttt tccagcagat tcgtgttgcg attattccat atttctaaac
     1681 caggtggctt gttttttgcg atgctttctg ccatgggaac gagcatgcag ctgccaatcg
     1741 ctcaattacc gatcgtctca ctttattttt ttatgggtgt cgtttttgcc ctgattgcgg
     1801 cagtgattac aaaattactg gattcacggc ctgagcagac aattgaaaaa gcaactttaa
     1861 aagaaagatt tcacgaagag cctttagtga tcattgattc tgttttctac agcgctgcct
     1921 tatttctttc cgtttatgtc agtcacggct tgaatctgca taatccttat tggttgacct
     1981 tgtcatgtgc atcgattttg ctagcagaaa acttggatgc gatgaagcat cgacaagtcc
     2041 aatatctgat tggatcgatg ggtgggttat gtgtgtcggc attcttgtca tttgtgccgt
     2101 ttacgcagtt gcagaccatt tttctgatca cttttctata tggaatcgca caatttctag
     2161 ttgctagaaa ttatgcagtt gctaatattt ttcttaatcc gatggcgttg atgctatcta
     2221 cacttattcg tggagcatac ttgatttctt tgatcgaata tcgtttttta gggatcgtca
     2281 taggaagttt catcggttta ggtgttgcgt gggtaatgac ggttggtttg caacattatt
     2341 taacggttgt tcgtcaaaaa ttagaataga aggacaaata tatgtgccaa aagaggttat
     2401 gacaagattt ttgtcacaac ctctaattca aggtgttcaa aagccagatt ctcagcatta
     2461 agtcaaattc acacaaaaat gtggaaagga actttcaaaa aaattttata tttattctat
     2521 caaaaaattt tgtttatgat ggtaactgaa taaactttcc tgagatggtc aatgctttcc
     2581 ttgaaagtct tacagatatt ctttcttcat agaaagttta agttttatag ttagtgtaca
     2641 ataaaagtat gtttatacca tatggtgtcc ggataatcag tcatttaaac aatgaggttc
     2701 aaagatatga aaaggggaaa tttgatgaag aaaataagca atgaaatcca aattctggca
     2761 gaaactttaa ctcttcccaa agtcgttata gagcaaatga ttgtacaagc aaaaaacatc
     2821 cttgatgagg tgtttgagca atatagtcat gaactaatgg atcctaataa agcaaaggcg
     2881 actgcaaaga aaatagacaa agtctatgaa gaggaacctt ttgcagcatt agctatttat
     2941 ctatatgcag cttctcaaag ttggaaaaaa atttatcaac cattgaagat tccaagaact
     3001 atctatttgg caacaatgaa tgcttttact agatttattc atgaacattt ccaagtaaca
     3061 ggaagctatc gctttgaccg tggtttttgg atttggcatt acactagtgg cttgatcttt
     3121 cggattggtg aattggagta cgaaatgaca tattttccga aagggtacac ggatctaaga
     3181 ttagaaggaa agcagtgcct ttctcttcat attccttccg atgcagattt atctcagaat
     3241 aagataagag atagttacga aagtgccatt cgtttttttg aactttattt tcctgattac
     3301 cattaccaag tgatgtacac agatacttgg ttactatcac ccaatcttac taaatagttg
     3361 aaaaaagagt caaaaatctg tctttttgca gccgattatc gattattatc agttgatgaa
     3421 caggacgata gtggagtccc ttggatcttt ggacgagtag atgcccaaat acatgattat
     3481 ccagaaagta cgagtttaca gcgacaagca aaagagcaat tgcttgcagg cgagcacatt
     3541 ggctctggct taggtattct tacttcataa gtttagtact tcgaaatagt ttaaaagagc
     3601 gtgagacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag
     3661 cagaagcaac tccttcggaa ataagctgaa attcacaaaa atttgaaaag caattttcgt
     3721 gaatttcttc ttatttcttg gagttaaacg cttctgtccc agcctctttt ttagtgttct
     3781 atcgaacaca cagtacgttc aataggtaaa ctagctataa caatagatat taaagttaac
     3841 ggacaagagg gcctttttta ggtagctaaa acgtaataat gaaaatttat ttccagagat
     3901 aggagtcaat cagctagtct gatcgactgt tttaacaagt tgactttcat tttaactttt
     3961 gataccattt aaaacacaaa tcgtaattgt ttcgatttgt gttttttagc atgactacaa
     4021 tcaaagaaga aagtgggtcg tccatatgga aaaaacagat atctcaagtg cataccgccg
     4081 cttgaaaagc ccaaatatca aaacacgaaa acgtgcgctg aagatcatca aagatgtgaa
     4141 acggaatagt gggaaaaggt aagaagaagg aaacttaatt aaaaaaatag ccgaaaaacg
     4201 tttttcggct attttcaata atcggttttt gtgtaaggtt tccgaaagaa ctgctgttga
     4261 ttttccattt ttaacatatg ataaattggt agaatctttc ttttcaaatt gataccattc
     4321 cctaattcca gttatatagt taactacaga accacaaagc acgtacgttt ataaaagtat
     4381 tatctgtagt tatttttcaa ttccctttca acctcttatt ttgaccagta gtattgatca
     4441 ctttaccttt taacaccttt gttcgttttt gaaacatttt tagtcaagaa tggaaacgta
     4501 actacataat caaaggtttt gcgaaatatt tcatgaaata tttcatgtag aagcgagcaa
     4561 tacggttgca aataaccatt atcgtttaat aagcagttac gaaagctccc aatatctcta
     4621 acgttcagct cactccattt cttttcttca aaaaaatcag tgattcgtat ctctttctat
     4681 ttgtcgaaaa agttaacttt aaaaagtaac gccgaaaaaa tatgcaaaaa aataaaaaag
     4741 cagttactat tgctagaata acatcaagga ataataagtt ttggttttca gataatagtc
     4801 gataagttgt gtattggaat tttagataca gtaataaagt atttttcatg aaattttgtg
     4861 agaatcacta ttacaagtat ctttaataaa attaatggtt aaggaggaac ttaaagtaga
     4921 atgtaaatga atagttgtag tcagtcgatt gtgatactag actcaaagtt gcaggaataa
     4981 gtttttcaat ttgtgattgg aagataaaaa atgaaaaaga agggcttttt tttatacttt
     5041 gttgattgta gtgtttattt tccctctgtt tagccaagta acattttcta tgactcaacc
     5101 agtttcaagt gaggaacatg ataacctttt tcgtgctaca gaagagttta agaaatatca
     5161 ggaaaatatt gttccggaga ctccattagc tagtgagcca attactgata ttgatggaaa
     5221 ccaaatagga tggtatatac agtacgaagt tatggtggta aataatgact caatagtaaa
     5281 aaatacagta ggcttagagc taacaccgat tgaaaaggtg agttcattgt taacgtatat
     5341 ttatactgat gaaagtgacg agactgagat cattttaacg gattactcaa aaattgctac
     5401 tgataaaaag tatatattgt ggatgtagac actagtgaaa tactttatga tatagaaatt
     5461 gatgaaaatt tactagatgt agcacaagaa atcgatcatc aaaagcagga agctattcga
     5521 tatgctggta gaaaagggaa aagaaaatat ttattacgtg aatgtagcaa aagttagaga
     5581 agatgaaaat gagtggaaag aattcaagag tcgctactca attaactcga ctccgacatt
     5641 tacagtttac agagaaggat cgatagaaaa aactgttttt tggactaaag aaagtggaat
     5701 gtctttagct gaagtagaag agtttttgga ttatgttagt atgcaacagt aagggagttc
     5761 ttattatgaa aaattttgac acatattatg ttattgtttt ttcgatatct ttgctgttaa
     5821 tattactaac tttaatgcag tataaagagt atccagagta ttttatttta acttttgtat
     5881 atttagtaag tagctacaca cttctatata aattcagaag ttcttctaga gtttctaaag
     5941 tttgtttctt aattagctta ttgattctat aatatttttg atttatatag gaaattaaaa
     6001 atattataga atcaacactc agagaacggg ttggttttta atagatttaa taagtactga
     6061 taatgaaatt tctcctggtt gggaaaacga agttggttac cctgtagaag aattttttca
     6121 agattacttt gcggagtatg ccgataggat aatgagagat tacgtaacag ataaaactca
     6181 agaagtcatc aatcaatccc agtcattaaa tgaattatct gataaggcga aagaagaagc
     6241 agttgccatt atttcttcag ggattagtga ctatattgat atgagtggtg aaatcaatta
     6301 tggcgataaa gacaaaattg tacgcatgat aaaagctttt atcaaaactt ttgatgtgaa
     6361 ggcagatctt aagtttaatg atacttacct agtaggaaaa ttaattaata tccttgggac
     6421 agagaaagat acggaaacgt ttatttcctc tttgtctatg ttgtttacag ataagcattt
     6481 ttcaactcag cttggtggag aggaactagt ggaaatcttt taaccattac gcccagcatt
     6541 aataaaagta tatcaaaaaa gtactcctga tgatttttaa gattggtttg agaaataatg
     6601 tgaaaacact atttttaatg ttaattatag atagagatga acgcgtcata tggttaaaag
     6661 aatgaaaaag tcaaagatac actgctatat ttcactaagg atatagcagt gtatctttca
     6721 tgtcgtttca ctggcagttt tttataaaag gaggtgtgca tttcagttgc ttttctttgg
     6781 tagttagttg aatcgtttaa gaattaacgg atgtggcaga caggtgctct gtccaaaaac
     6841 cagtaaaatc tttgatggtt ccatctttat ttagctgtgc ctgttcaaat actgttttgt
     6901 ttttaccgaa tggatcaatt gcaataattg ttccgatccc cgcacgtttg gcagcaagta
     6961 atcctgagta agcatcttcg ataacaagac aatcagccgg agctaagctc agtttgtctg
     7021 ccgctttaag aaaaatatcc ggttgcggtt tcccagggaa agagccgtcg tcatagacaa
     7081 tcttgtccca gtcaaaccag cgggctaaat cgaaaatatc aaaataaaaa gcaacattct
     7141 ctttgacagt agccgtggca atcgttaatg gaatctgttg gtcagtcagc tggtcaagag
     7201 tcgcttcaag cccttttgtc aactgaagct cgttttcatt ttgcaagcaa agcatacgat
     7261 aatagctttc tttttcttct gacaatacgg cgatctcaga ggcggtcaaa tgctctgaaa
     7321 tgaaatgttt caaaatctcc gtattcgtcc gaccatgaat attttttaaa atatcctcgt
     7381 ctgataaacc atcttttgta tgatcatgta tcatatgcag ccaagcagct tcatgcagat
     7441 gagagtccaa aaacattgtt ccgttgaaat caaatataat ccctttcata gttacgctcc
     7501 tatagtggta ttttcggttg aatcagcaat ttgcagatcg acatattgtg catagtgctc
     7561 ttgaacctcc cgcgagatct ggcgatccgt aatgagcaga tcgaaatcat gcaaattata
     7621 aaacacataa aaatcatctc gattgaattt tttattatca acgagtagat atttcttacg
     7681 ggaattattt agagcgatct gctgtgcttc tccttcttcg gtactgtaag tagagatcgc
     7741 ttcgttgtga acgccatttg aactgataaa tgcttttgta aactttagtc ttcttaaatt
     7801 gtcgttggtg atcggtccga caaatgcgcc ggtatttttc cggaaatcac cgccaatcag
     7861 tagaatttct ggtccatctg cttgagcaag aatatcaaaa actggataat tatttgtaat
     7921 gatccgaatt ttcttgttca gtaaatgcgt cgccaatagt tcgattgttg tacctggtcc
     7981 taagaaaatc gtttctccct cgtgaatcaa ggaggctgct gtggcagcaa tttctttttt
     8041 ttcttgaatc tgcagagtgg ctttttcagt gtgagaaagt tcttgatcta aagtgtagga
     8101 aagactttga gcccctccat ggacacgcag cagcttgccc gatttttcta attcatctaa
     8161 atctctgcga acggtcatat cagaaacatc taattgattg atgatttcat taacggtaag
     8221 gattcctttt ttattgacca tttctacgat agtaagcaat ctttcttttt tcaacattgt
     8281 cttcacctct aatttaagga taatctatca tataaacgga caacagtcaa tctaattcga
     8341 acaaaagtaa acatttaggg tggtttttat gtttgttaca atagatttta ttgctgtttt
     8401 ctggttttta tgattatttg tgtttgtttt tgttgacaaa tgttttggat gcgtttacaa
     8461 tgcaatcagt tagaaagagc gaaaactgat tatagatttg aggagagatg tacatgctta
     8521 aattaccaga agattttatt tttggcggag ccacagcagc ctatcaggtt gaaggagcca
     8581 ctaaggaagg tggcaaaggc gctgttgctt gggatgactt tttagaggaa caagggcgat
     8641 tcagtcccga tccggcaagt gatttttatc atcaatatgc aaaggacatt gaattgtgtg
     8701 aacgttttgg tgtaaatggt ctaagattat ccattgcttg gagccgcatt tttcctgatg
     8761 gagctgggaa accaaatcca gaaggaatcg ctttttatca tcgtgtgttc gaagaatgta
     8821 agaaaagaaa cgtaacgccg tttgtgacgt tgcatcattt tgatacccct aaacgtttgt
     8881 ttgaccatgg agattttttg aatcgagaaa caatagaagc atttgtttcc tatgccattt
     8941 tttgttttca tgaattcaaa gaagtcaagg tgtggagtac ctttaatgaa atctatccag
     9001 ttgcaaccaa tcaatatttg ttaggtgttt tcccaccagg aatcaaatat gattttacaa
     9061 agatcgtcgc ctgtcttcat aatatgatgg ttgctcatgc ccgtgtagtg aactatttca
     9121 aagaaaacga acttccgggt gaaattggtg tagttcactc attagagacg aaatatgcgg
     9181 caacagacgc gccggaagat aagcatgctg cctttttaga cgatgcattg tcgatccgtt
     9241 tcttattaga tgctacctat ttaggctatt attcaactga aaccttgact gctcttgatg
     9301 agatatgtga agcaaatcag gccagctatc attttcctga agaagatttc gttgaattga
     9361 aaaaagcatc cacgcgtaat gactacttag ggatcaatca ctaccaatgc cattttgtca
     9421 aagcttacga tggagaaaat gcaatccatc ataacggtac gggtgaaaaa gggacctctg
     9481 tttataaagt gaagggaatc ggagaacgta tttataaaga aggaattcct cgaactgatt
     9541 gggactggct gatttatcca gaaggtctat atgacttgtt gctgcgaatt aaaagcgatt
     9601 acccacatta caacaaaatc tatatcactg agaacgggat ggggtataaa gatcagtttg
     9661 aagatggcat tattatggat cagccgagaa tcgactattt gagagtctat ttggaatcct
     9721 taagcaaggc gataacagcc ggggtaaatg tgaaggggta ttttttgtgg tcgcttatgg
     9781 atcttttctc atggacaaat gggtataaca aaaggtatgg cttgttttat gttgattttg
     9841 aaacccagaa gcgttaccca aaagaatcag cttactggta caagttggtc agtgaaacca
     9901 aaacgattat ttaataagtg ataatggagg aagaaaagat gaataaagag gaattacaaa
     9961 tgcttggttt tgagatcgtt gcatattcag gcgacgctcg cagtacatta ttgaaattat
    10021 tgaaagaagt aagacaagga aactttgaac atgttgattc ggcgttgaaa gaagccgacg
    10081 aaaatttaac ccttgcacat aattcgcaaa caaaaatttt agcggaagaa gcatctggga
    10141 aagagatgga gatgggattc atttttatcc atgggcagga tcatttaatg accactttat
    10201 tgctgagaga tctgattcaa gactttattg tactgtacag acagaatcaa ggataggaga
    10261 agaacgctat ggatggaatc attaaacaaa tcgaaaaagg gaaaccattt tttgaaaaaa
    10321 tctcacgtaa tagttattta ggagccgttc gtgacggatt tttaacagcg atgccagcta
    10381 ttttattttc aagcattttc attttgattg ctgcggttcc tgagattttt ggttaccaat
    10441 ggcctgaatc tgtctccaca tggctatgga aagtctataa ttattcgatg ggtgttgtag
    10501 ggttactcgt ttcagcaacc actgctcgct gcttggctga ttcgatgaat cgtcgcttac
    10561 cgaaaaacaa agtaatcaac accacctctg tgatgctggc ctctgtggta agtttcctgt
    10621 tgttaagcgt ctctccgatt gaaggtggat tttcaacgga atatatgggg acaaagggac
    10681 tactggcttc ctttgtcgct gcatttttaa cagttaattt atataagttt tgtgtgctga
    10741 aagatattac cattaaaatg cctaaagaag ttcctggaac gatttcgcaa accttccgag
    10801 atatttttcc tttctctttt tcagtatttg cggccgtttt aattgattta ggcattcgac
    10861 aaatcttcca aatctcattt gcagaagcaa tcattacggt gctgcagccg ctatttacag
    10921 cagctgacgg gtacttagga atcgctatta tctggggagc gatggcgctg ttttggtttg
    10981 tcggtgttca tggaccgtcg atcgtggagc cggcaattgc ggcaattatc tatgccaatg
    11041 tggaaaccaa tctgcaattg ttcaattccg gtgaacaagc ttctaaagta ctgacggtgg
    11101 gtttagggaa ttttgtagga actatgggag gaactggggc aacattggtt gttcctttta
    11161 tcttcctact ctttgctaag tctaagcagt tgaaggcagt tgggaaagct tcctttattc
    11221 cagtaagttt cgctgtcaac gaaccattgc tatttgcggc acccatgatt ttgaaccctt
    11281 atttttttat tccatttttg ttaacacctg ttgtaaacgt ttgcctgttc aagttttttg
    11341 tcgatgtatt gggcatgaac agctttatgt acgttttgcc ttgggcaact ccagcaccga
    11401 tcggtttggt tctaggaacg ggcatgggta tcttagcttt tgttctagca gcggttctaa
    11461 tcgtcgttga cttcctgatc tatctaccat tttgcaaagc atacgatgct gtcttagtag
    11521 agaaagaagc acaaaaagca gaggtgatcg caaccgagga aggtgcttct gccgatgtac
    11581 gtgaggaagt acctgtggca gcgagtcaag ttatcagcga tgcaaataaa gaaatcaatg
    11641 tgttggtact ttgtgctggc gcagggacaa gtgggatgtt agctaatgct ttaaaaaaag
    11701 gtgcatctga atcgaaagca ccgatcagtg caatggcggg tgcttatggt tctcattacg
    11761 aaatgctgca ggattttgat atggtggtct tagcaccgca agtcaattct tactatgatg
    11821 atatcaaaga agacaccgat cgcttaggaa tcaagctggt tgcgacaaaa ggagcagaat
    11881 atatcggatt aacgagagat cctgaaaaag ctgttcagtt tattctgaac caatttcaat
    11941 aaaggaggag ccataatgaa aatgggaatt tggttgcgta aagctgtttt atttgcagct
    12001 gtgttagggg ctttgggggc tgtttcaaaa actgttgaag catctgccag cgaatttatt
    12061 cgcggagcag atatttcgat cctgtcagat atggaaaaat ctggtgcaaa atattatgaa
    12121 gacgatattt caaaagatgc cttagagatt ttaaaaaata atggtgtcaa ctatgttcga
    12181 ctgcgtttgt ggcaggatcc ttataatagt aatggagaaa gttatggagc agggacaaat
    12241 gatctggaaa cgacgattga ccttgcaaaa cgagcaaaaa atctgggact taaggtgctg
    12301 ctggattttc actacagtga tttttgggtt gatcctggga aacagaatct tcctaaagca
    12361 tggcaaggtc tgacctttga agaaatgaat acggcattgt acgactatac aaagaacgtt
    12421 ctgtcggaaa tgaagcagct ggacgtttat cctgatatgg ttcagatcgg caatgaactg
    12481 aatagcggaa tgctctggcc ttatggcaag tcttggggag aaggcggggg agaatttgat
    12541 cgattggctg cttttttgaa gtctggtatc caagctgttc gagacactca acctaaaaca
    12601 actccagtaa tgctccactt agctgatggt ggcgatacag gagcatttac ttggtggttt
    12661 gatgaaatca cgagtcgagg tgtgtcattt gatttaattg gagtgtcgta ttatccgtat
    12721 tggcacggtt caatgaatga acttcaaacc aatatgaatg cgatcagcca acggtatggt
    12781 aaagaagtga tcgtagttga aacagcttat gggcatacaa cagcgaatgc cgatactatg
    12841 ccaaatgctt ttggtgaagc cgaagcagct gcggggggat atgaaccaac accgacagga
    12901 caagcagagt atttgctgga tcttgccgat cggattcagg cagtaccgaa taatcgcggg
    12961 gcgggcttct tctattggga acctctttgg tacaacggaa atgtgagttg ggcaacacaa
    13021 gcaggtatga attatctcag tgttcaatcc actatgggaa acgaatggga caaccaagcg
    13081 atgtttgatt ttgctggaaa cgccttgcca agcttgcgtg cgtttaaaca agcaggggcg
    13141 caaataaatc tagttaaaaa tgcaagtttc gaaagcgatg gaccaacgac cagtccttcc
    13201 aattggcaaa cctggtttca acaaggaacc gctaagggta cgatcaaaac ggaagcgggc
    13261 actttttttg gggactacaa actaactttt tggcaggatc aagcatacga ggcatcagct
    13321 tatcaaaatg ttagtggcat aagcaaagga acttacacat tgagtgccta tgtaatgtct
    13381 gggggagagt ttgatactaa tcagttatat atcaaaaatt atggtggagc ggaactaaat
    13441 actgcggttg ttaaaacaag tgaatggaca aaaattacaa tcaaagacat tccaattaca
    13501 acaggtgttt gtgaaattgg ggtttatagc aaggcttcag gaaatgcttg gacgaacgtt
    13561 gattttgttt cattggtgaa acaatagact gcggatcgtt tcgattcaag atcggaggtt
    13621 cccttcagcc acatcgttag cgtagaaggc aggaatcgaa cctgcacctc gcctttgcca
    13681 aaaataacca gaaacgattt ccagtcattt ttaccaaaac gagtaaagca ccagacttca
    13741 tctacacttt gtattatgct aaagagagtt caacgatttc gtaagaagca atgaaaaaat
    13801 tgcaaaaagt tgtgcagata acataaagtt tgtttaagaa agggtaacct tagaattccg
    13861 tcgtgaatat gatttgagca cttagatgga tagaaaaaag ttctcggaaa acagttcgtt
    13921 tttcgagaac ttctttttat gataagaatg aaacaaatta acttatatta tagtctcttt
    13981 tggtagggaa ccatcttatt tttaatgaaa atcaagcatt ttagctattg aagaatgttg
    14041 atttataggg attccccctc catattatgt tggctcttta ttcccactcc actgttgctg
    14101 gtggtttaga agtgatgtca tacacgatac ggttgacgtg ggctacttcg tttacgatac
    14161 gtacagagat tttttgcaag acttcccatg ggatacgggc aaagtcagcg gtcattccgt
    14221 cgattgaagt tacagcacgg ataccgactg tgtagtcgta agtacgtccg tcacccataa
    14281 caccgacaga gcggatccct ggaagaacag tgaaatattg ccagatatca cggtcaagtc
    14341 cagcagctgc gatttcttca cgcaagatag catcagattc gcgtacgatt tctagcttgt
    14401 cttcagtgat ttcgccaaga acacgaatac caagaccagg accagggaat ggctgacgcc
    14461 aaacgattga atcaggcatg cctaactgag tccctaattc acggacttcg tctttgaata
    14521 atgtgtttaa tggttcgatc aattcaaatt gcatatcttc tggcagtcca cctacattat
    14581 ggtgagattt gatcgtctgt gctgtttctg taccagattc gataacgtca gtatacaacg
    14641 ttccttgtgc taggaaagag acgccttctt caccagcaag ttttgttgct tcgtcatcaa
    14701 aaacatatac gaattcattc ccaatgattt tacgtttttg ttctgggtca gatacacctt
    14761 tcaacttgtc taagaagcga tctcttgcat tgactttgat gatgttcaag ccgaattttc
    14821 cgcctagact ttccattact tgttccgctt cgcctttgcg tagcagaccg tggtcaacaa
    14881 agatagatgt caattggtca ccgatcgctt tttgtaaaag aaccccaacg acactagaat
    14941 caacgccacc tgaaagacca agcaagactt ttttgtcacc aacttgttca cggatttttt
    15001 ctacttgcat atcgataaag ttatccattg tccagttacc ttcacagtga caaacatcaa
    15061 aggcaaagtg gcgcagcaat tcgattccgt attcggaatg acgtacttct gcatggaatt
    15121 ggataccata aaaattacgt gttgtgtctt ggatagaagc aatcggacaa tctttgcttg
    15181 ttccgactgt ttcaaagcct tcaggaactt tagttaccaa gtcaccatgg ctcatccata
    15241 ctgtttgttg ttttggtgtt tctttaaaca agacagcttg atcgcttgtt acttctaaca
    15301 aggctttccc atattcgcgg tttttagcag gctctacgga accgccaagt ttgtacgtga
    15361 tcaattgcat accatagcaa atccctaata caggaatacc taaattgaag atctcaggat
    15421 cgatcccaaa tgcattctca tcatatacac tgtttggtcc gccagaaaga atgattccct
    15481 ttggattcat cgcttttact tcttctgcag taatgcggtg gctcaataat tcggaaaaga
    15541 ctccaagatc acgaatacgt cttgtgatca attggttata ctgactaccg tagtctaata
    15601 cgataatctt ttcaacgttc gtcatatcgg caacgtttgt caaatttatt acccctatcc
    15661 ctttaaattt tatctcaaaa tagtcaaact attttaaaat gctaatattt tcgcatgaaa
    15721 atcgaatcga tgatatgatt ttcagtttta tggagaatta tatcggctct tcctcgtgta
    15781 ggcaagatat attcctgtaa atttttcaaa ttcacatttt tccatacatc ttttgccatt
    15841 ttaaaggctt cttcacgatc tccgatagca aaacgataat aataattctc tggattttgg
    15901 aaagccgtat ccagtaacgc accaaaacga tccaaatacc atttttcgat cagcacggga
    15961 tcggcatcga catagacaga aaaatcaaaa aagtcgctga cgtagatttg ctgattcgca
    16021 ggtaattgaa gcgtattgat cccctcaacg atcaagatat caggctgctg gatcaattcg
    16081 tacttgtctg gaatgatatc atacacatca tgtgagtaaa caggtacttt tatctcttcc
    16141 tgaccagatt ttacacggtt caagaaatcg atcagcatct ccatatcata actttcagga
    16201 aatcctttac ggtccatgat tccacgctct tttaatatac gatttggata aagaaatccg
    16261 tcagtcgtga tcagctgaac gtttcttcgt ttgaaggtac gagacaaaat cgtctgcagc
    16321 agtctggctg ttgtactttt tccaacggct acacttccgg cgatcccgat aataaaaggc
    16381 ggtacttcta cgtatttatg aagaaataaa cctttactca agaacaaaga ttcaaattct
    16441 ttcatataaa gataaatcag atgagcaaga ggtacataga tatctcgaac atcctgcatg
    16501 gaaatgcggt cattcaaact tttgatatta tctagttcat cttgtgtcaa aggtgcttgc
    16561 ccattacgat aaaattctcg ccattcttct cttgccacac ggtagtagtt cattggatca
    16621 ttcatattag cctcctgcgt tctcccatca atggaactat tttaacacaa aataaacgca
    16681 aaccccacca cttaagagag attgccgatc tttttgtata atctttataa tagaaagaaa
    16741 cggagtctta ttcttgactt gcgcacggat acataaaagg atagactgtt gtcatgaaag
    16801 aaatgagaag gatggaagac atgacaaatc attactattc tgaacgccca gatacggcgc
    16861 acgattttga acaatgggct tttgagttaa aaggcagaac ctttcaattt gtaacagatt
    16921 ctggtgtatt ttcacgtgaa acagtggatt atggttcacg tgtcctgatt gatgctttcg
    16981 attgggaaga gttacctgat gaaggaaaga tcttagatgt gggatgcggg tatggaccga
    17041 ttgggttagc tttggcattt gcgacacagc ggtttgttga aatggtcgac attaatgaac
    17101 gagcggtaag tctagcgcaa ggaaacgcaa agcgtaacca aatcgaacat gttgatatcc
    17161 atcaatcgaa tatctatgaa gcagttcatg aagaaaccta tgcagctatc gtaagcaatc
    17221 cgccgatccg tgctggaaaa aaagttgtac atgaaatttt gacaggcgca tatcctcggt
    17281 tgaagaaggg cggtacactg acaattgtga tccagaagaa acaaggagcg ccgagtgcgc
    17341 aaaagaaaat ggaagaaaca tttggtaatg cagaaatcgt cacaaaagat aaaggatatt
    17401 atatcatcaa aagtgtgaaa gaataactag ctgaaaaata gtggagcgac gaaagagtgg
    17461 aactgggcgt gcatgtacgg gtacgtatca gttctttttt tgttgagaag tttttaaaaa
    17521 caaagaacta ttttttcttc aaaaagaaat agtaggaaca gagtcgttgt tttttacgat
    17581 aaaataaata agatacagaa cttgtataga aggctgccaa gtcggtagat aaaggaggtt
    17641 tttatcaaaa aacatacttt ccttttttct ctattctttt cttgggggtt ttggtacact
    17701 gatagggaat ttagatagaa gggagccaat aggatgaagc tgaccatcag agatatcgca
    17761 gaaatggcag gcgtatcagt aacaactgtc tcacagattt tgaataacaa aggaagcaga
    17821 tttagtgata agacaagaaa aaaagtgttg tcgatcgtga atgaacatca ttataagccc
    17881 gattatttcg cttcaaatgt gatcaatcga cattcaaaga ccatcggaat gatcgtccct
    17941 gatgtcactg atttcttctt ctccaaactg atcgaaggtg tagagagcta tttgaatcct
    18001 ttgggctatg tgatcatgtt atgcaattct cgtcatagcc aagaaaatga gatcaagtat
    18061 ttacaagagc tttcccaccg ctcagtggac ggaatcttgc tggccacacc aaatatttta
    18121 cctgagaaat atgcattaga cagcggtttt tatcaaaaaa tgccaatcat tttaatcgat
    18181 cgcggattga atcgtcggga taacggacgg cttatcgtaa aggaatatga gggcgcctat
    18241 caagctgttt cgctgtttat tgaaaatggc catacgaaga tcggcatgct gaaggaaacc
    18301 actggatact atcaattaga agaacgtttc aacggatatc gtcatgcgct gaaagatcat
    18361 ggcctgcctt ttaatgggaa atttgttgaa catggagagt tgactgtcca aggtggatat
    18421 actgcatcaa aaaaattact caaacataaa gatatcacgg ctattttttg cgggaatgat
    18481 gccatggcga tcggatgcta tcaggcgatc gatgaattgg gcaaaaaaat cccagaagat
    18541 atctcagtca taggattcga tggattaaag ctgtcagaat acatgattcc gcaattgacg
    18601 acagtgcagc agccaagttt tgatattgga ttttatgctg cacgtttcct gatcgatacg
    18661 atcgaatttc ctcaaagaaa agttccgaac aaagtgttcg aaacaaaatt aattattcgt
    18721 gagagcgtaa aagtattgac aaagggctaa ctcggcggta tattgcttat gtaagcattt
    18781 acaaaggcta gttagtgctt tttttatttt tagtaaacca gtttactaaa gtggtttacc
    18841 tttcctaaaa ataatgtata ataccgaatg aagacaagga ggatcaggca atgcgaatgg
    18901 tggatctgat tgaaaaaaag agggatggaa acgagctgtc gaaagaggaa atcgagtaca
    18961 tcgtcacgaa ctatacgaat ggaaagattc cagattatca agtcagtgca ttattgatgg
    19021 caatttttta tcaagacatg acaaatgaag aaatcacgaa cttaacattg gcgattgcta
    19081 attctggtga tgtcatcgat ttgagttctc ttgaaggaat aaaggtagat aagcattcga
    19141 caggtggcgt tggtgacacg accacattga ttttagcccc cctagtagct agtgtcggag
    19201 tgacagtggc taaaatgtct ggacgcggtc taggttacac aggtggtaca ctagacaagc
    19261 tagaagcaat tcccggattt cagatcgagc tttcggatga agaatttgta cgcattgtta
    19321 atgaaagtaa agtagcggta attggtcaat caggaaactt ggcaccggcg gacaaaaaat
    19381 tgtatgcctt gcgtgacgtc acagcgaccg ttgattctct tccgctgatt gccagttcga
    19441 ttatgagtaa aaaaatcgcg gcaggagcag atgcaatcgt tttggatgtg accactggag
    19501 acggtgcttt catgaagaac atcgaagatg caagacgtct ggcaaagacc atgacgagca
    19561 ttgggaaact ggctaaccga gaaacagtgg cggttatctc agatatgtca gaacctcttg
    19621 gcgaagctat cggaaatagt ctagaagttg tcgaggcaat cgaaacatta caaggaaatg
    19681 gtccagaaga tctagtagaa atgtgctacg ccttaggaag ccaaatggtt gttcttgctg
    19741 gcaaagctaa gacaaccgat gaagcaagaa cgttgcttca agaagctctg gaatcaggta
    19801 aagcgttagc aaaattcaaa gaaatgatcc aaaatcaagg gggagaccca gcgatcgtgg
    19861 aacatccaga acgaattttg actgcacgct acacaatgga gcttcctgct aaacaaagcg
    19921 gagttgtgtc aaaaatcgtg gcaaatgaat taggaattgc tgcaatgatg ctaggtgctg
    19981 ggcgtaaaac caaagaagaa gatattgatc acgctgttgg attgaaactg cataaaaaaa
    20041 ttggtgacac tgtgacaaaa ggtgagtcac tattgacgat ctatagtaac gacgaagaaa
    20101 tcacttctgt cattgaatta ttatataaaa atattgaaat tggtgaatcg gcaatgaagc
    20161 caacgttgat tcatgacatc atcacagaat aaaggaaaaa agcggacttt accgttttaa
    20221 agaaaagggg aaaagaaatg gaactaaacc gaatgatcga ccatactatt ttgaaagcag
    20281 acgcatctaa agaagctgtg atgcaaatta tcgaagaagc aaaaaaatac catttttatt
    20341 ctgtctgcat caatccagca tgggttgcgc tagcgaaaga acaattacaa ggtgagccag
    20401 tagccgtatg tacagtaatc gggtttcctc taggagcaaa cacacccgag acaaaagcat
    20461 ttgaaacaac agatgccatc aataacggtg cagatgaagt cgatatggtc atcaatatcg
    20521 gtgctttgaa atcaaaggat gatcaacaag tccaaaaaga tatcgaagca gttgttgaag
    20581 cagcaaaaga tcgtgcgctt gtcaaagtta ttattgaaac atcgttatta gatagagaag
    20641 aaatcatccg agcttgcgaa atagcaaaag ctgcaggcgc tgattttgtc aaaacatcaa
    20701 ctggtttctc aacaggcgga gcaaaggtag aggatgtccg tttgatgcgt gaaactgtag
    20761 gaccagaaat gggtgtcaaa gcttccggcg gtatccataa cgaagaagaa gcaatggcaa
    20821 tgatcgaagc tggtgctaca agaatcggaa caagcgcagg agtagcaatc gtatctggtt
    20881 caactggtga aggctattaa ttttttcaaa ggagaagctc atggcagaac tcaaacaaga
    20941 atggatcaac acagctattg aagcgttaga taaagcctat gttccttatt cccattttcc
    21001 ggtaggcgct tgtctcgtaa cggaatcagg caagatttat caaggcatca acattgagaa
    21061 tgcatcattt ggattaacga attgtgccga gcgcacagct tttttcaaag cagtatctga
    21121 aggagaaaaa acatttacgc atctagtcgt agcggggcac acccccgatc ctatctctcc
    21181 ttgtggtgca tgtcgacaag taatggcaga attctgttcc cctgatatgc cggttacgct
    21241 agtaggagac aatggtgtga cgaaggcaac gaccgttcgt gcactgctgc cttatgcatt
    21301 tactgaaaaa gatctataac tcatgttcat tcagtcagct gactgttgaa aaataaaaca
    21361 attattttag gaggctttac agaaatgaaa aaagcaaaat tatttggttt aggtgctgtc
    21421 gcactagcag cagggttatt tttaggtgca tgcggcaaca acggctctac tgattcatcc
    21481 ggtggcaaaa gctcatcaga cacaacaact gcagcattga tcacagacac aggtggtgta
    21541 gacgaccgtt cattcaacca gtcagcttgg gaaggactag aaaaatgggg gaaagatcaa
    21601 ggactttcac gaggaaatga tggcttccaa tatttccaat cttcaaatga atcagattac
    21661 atcccaaata ttgaccaagc attgaatgct ggattcaaaa cgatttttgg tattggttat
    21721 aaactaaaac cagcgatcca agaacaagca acaaacaata caggtacgaa ctttgttatt
    21781 atcgatgatg tcatcgatgg attagataac gttgtatctg caactttcaa agacaacgaa
    21841 gcttcttatc ttgcaggtgt tgcagcagct tatacgactg aaacaaacgt agtcggcttt
    21901 atcggcggtg taaaaggtga agtaatcgat cgttttgatg ctggattcaa agccggtgtt
    21961 gatgcaggtg cgaaagaatt aggaaaagaa atcaaagtat tgaatcaata tgctggtgac
    22021 ttctctgctc cagataaagg acgttcaatt gctcaaggta tgtatgcaca aaacgcagat
    22081 atcatcttcc atgcttcagg cggtacaggt aacggtgtat tccaagaagc aaaatcattg
    22141 aacgaatcag gcgacaaaaa agtttgggtt atcggtgttg accgcgacca atcagacgaa
    22201 ggcgaataca cattaaacgg cgaaaagaaa aacttcacat tgacatctac actgaaagca
    22261 gttggaacag tagtagaaga tttggcacaa aaatcagcgg acggtaaatt ccctggcggc
    22321 gaacacactg tttatggatt gaaagaagac ggtgttggtc taacagaagg acaactttct
    22381 gacgaagcga aaaaagcagt tgatgaagca aaagaaaaaa tcatttcagg tgacgtaaaa
    22441 gttccagaaa ctcctgaaga aaactaaaac catttctata gccttgttag acacatgttt
    22501 gacaaggcta tggtttgatt agaacaagaa ttgttcattt atccaagctg ccttgtgaca
    22561 gtttggataa gggaacaact ccctgaagta atgtttgttt caaaagaaga acgctcacta
    22621 agcgtgaatc ttagtcaatc gttgccctag atagaaatcg ttaggatgtg aaaaaaaggt
    22681 ggttcaagaa aatattgtca tagaaatgca gaatattacc aaagaatttg gaacattcaa
    22741 ggcaaatgac aacatcaatt tacaagtaaa ggcaggagaa attcatgcgt tgcttggaga
    22801 aaacggtgct ggcaaatcta cattgatgaa cgtgctttcc ggattattag agccgacatc
    22861 agggaaaatt ttgatgcgtg ggaaagaagt aaagatcaca agtccgacca aagccaacca
    22921 attagggatt gggatggtcc atcagcactt tatgcttgtt gatgccttta ctgtaacaga
    22981 aaacatcgtg ttgggaagcg agcctagtcg cgcagggatg cttgaccata aaaaagcacg
    23041 aaaagagatc caaaaagttt ctgaacagta tggattgtca gtcaacccag atgcttacgt
    23101 tcgtgatatt tcagttggaa tggaacaacg ggtagaaatt ttaaaaacac tttaccgagg
    23161 agcagatgta ctgatttttg atgagccgac agctgtattg acccctcaag aaattgatga
    23221 attaatcgtg atcatgaagg aattagtcaa agaaggcaag tcgatcattt tgattacgca
    23281 taagttagat gaaatcaaag cagtagctga ccgctgtaca gttatccgcc gtggaaaagg
    23341 aatcggtaca gtcaacgtta aagacgtaac ctcacaacaa ttagccgata tgatggttgg
    23401 aagaacggtt tcattcaaaa cgatgaaaaa agaagcgaag cctcaagaag tcgttttgtc
    23461 tattgaaaat ctagtggtga aagaaaatcg tggattagaa gccgtgaaaa acttgaactt
    23521 agaggttcgt gctggcgaag tacttggtat cgctggaatc gatggaaacg ggcagtcgga
    23581 gttgatccaa gctttgactg gtttgcgaaa ggcagaaagc ggacatatca agctaaaagg
    23641 ggaagacatc actaataaaa aaccccgaaa aatcactgaa catggtgtag gacacgtgcc
    23701 agaagaccgt cataaatacg ggttagtcct agatatgaca ttatctgaaa atatcgcact
    23761 acaaacctat catcaaaaac cttacagtaa aaacggcatg ctgaattatt cagtaatgaa
    23821 tgaacatgcc agagaattga tcgaagaata tgatgttcga acaacgaatg aacttgttcc
    23881 cgcaaaagct ttatcaggcg gaaatcagca aaaagcaatt atcgctcgtg aagtcgaccg
    23941 agatcctgat ctgttgattg ttgcaaatcc aactcgtgga ctggatgtag gtgcgatcga
    24001 atttattcat aaacgtctga tcgaacaaag ggacaaatac aaagcagtgt tactgatcag
    24061 tttcgaatta gaagaaattt taaatgtttc ggatcgtatt gctgttatcc atgaaggaga
    24121 aattgtcggt atcgttgatc cgaaagaaac atctgaaaat gaattaggtc tattgatggc
    24181 gggctatacc ttagaagaag cacgaaaaga gttagaaaag ggggctggcg cacatgaatg
    24241 atcgcagcga aaaattccgt aatttattag tgcctgtact ttcagttgtt ttaggattga
    24301 tcttaggcgc gatattgatg gctgcttttg gttttcagcc catccaaggt tattcttcta
    24361 tgctagatgc agcccttggt tcgcaaagag ggataggtga aacgttaagg caagcaacgc
    24421 cgttgatttt tacagcatta ggtttttctg tagctaactc agctgggttt ttcaatattg
    24481 ggctttctgg acaagcactt tgcgggtgga tcgtcagtgt ctgggtggca cttgcgtttc
    24541 cagatctgcc aaaagttgtt ttgcttccgt tatgcgtgat cttaggtgcc ttagctggtg
    24601 cgatggcagc ggctgttcca ggtttacttc gagcattttt tggaacaagt gaagtgatcg
    24661 taacaatcat gatgaactat atcttattat acgtaagcac atttgcttta catgaagtga
    24721 tgcctgaaag ctatcgctca agtttggact cttccaatat gatcagtcaa aatgcctcac
    24781 tgcggttacc atggttaaca caagcttttg gcggctctcg cgtaaactca ggattatttt
    24841 tagcaatcat cgcgcttatt ttcgtttggc tgctgatgaa gaaaacgact ttaggatttg
    24901 aaatccgttc tgttggattg aatccttttg cttctgagta tgcaggaatg agtagtaaac
    24961 gtacgatcgt tttgtcgatg gtcatttctg gcgctttggc agggcttggc ggtgtggttg
    25021 aaggattagg aacgtatcaa aacttctttg ttcaaacgac ttcgctatct attggatttg
    25081 acggaatggc tgtttccttg cttggttctg gatcagcaat cggtattctt ttatcagcga
    25141 tcttgttcag tattttgaag atcggtggac ttggcatgca gacaggagca ggtgttccgt
    25201 ttgagatcgt caatgtatcg attgctttga ttatcttctt tgtcgggatc aacttcctga
    25261 ttcgtttcgt catggctaaa gtcttccaag ggaaaaaaca agaagagatc gttgcgacaa
    25321 tagaatcgaa accaacgaat caaaaccatg aagggggcga actataatgt cgactatcga
    25381 attaattgcc ttgatcctta cttctacact ggtttattca acaccgctaa ttctaacgtc
    25441 actaggcgga actttttctg aacgaagcgg gatcgtaaac gtagggctag agggaatcat
    25501 ggtcatgggt gcttttagtt ccatcgtttt caacttgacg atgagtccat cacttggttc
    25561 tatgacacca tggatcgcta ttttagtggg tggcgtcgta ggtatcctat tttctctgat
    25621 tcacgcagta gcaacagtca gtttgcgtgc tgaccatatt atcagcggga cagtaattaa
    25681 tctgatggca cctgctttag gtgttttctt gatcaaagca tggtatggta aaggtcaaac
    25741 tgataacatc acgcagaatc tggggtattt ttctttccca ggattagcag atattccggt
    25801 cattggacca attttcttta aaaatacatt cttacctgct tattgtgcta ttttgattgc
    25861 tgtcctagct tgggtgatca tcttcaagac gaaattcggc ttgcgcctcc gttcagttgg
    25921 tgaaaatcct caagctgccg acacattagg tatcaatgta tatgctatgc gttattcagg
    25981 cgtactgatt tctggcttgt taggcggtat gggcggtgct gtttttgctc agtcgatttc
    26041 cggtaacttt tcagctggta cgatcgttgg acaagggttc atctccatgg ctgctatgat
    26101 ctttggtaag tggaatcctt taggggcaat gggtgcctca ttgttctttg gttttgctca
    26161 aagcttgagt atcattggcg cacaattacc agttatttct tcgattccgc cagtattgct
    26221 gcaaattgct ccatatttgc tgacaatcat tgtgctggtt gttttcttag ggaaagcttc
    26281 tggtccaaaa gcaaacggga agaactatat caaatcaaaa taatctttta gcgaataaaa
    26341 agggtgggtt acgggaagtg tttttcgtct cgcccttttt gttttaaagg caataaaaat
    26401 aaaaagaaag aaggaataat catgtttaaa cgcgtacatc tgatcgtcat ggattcagta
    26461 ggaattggag aagcaccaga tgccgataag ttcggtgatg ttggttctga tacattagga
    26521 cacattgcga aagaagcagg attgaacgtt ccacatttag agcagcttgg tttaggaacg
    26581 atccgtcctc ttgaaggtgt ggaatcagtg aaagatcatc aaggctatgc gacgaaatta
    26641 gaagaagttt ctgtagggaa agatacgatg acaggccact gggaaatcat gggattgaat
    26701 atcaaaactc catttcgtgt gtttcctaat ggattccctg atgatctgat caaacaaatc
    26761 gaagaatttt ctggccgtaa agtcgtatgt aacaaacctt atagcggaac agctgttatt
    26821 gacgattacg gtgaacacca aatgaaaaca ggcgatttaa ttgtatatac ttctgccgat
    26881 cctgtccttc agatcgcggc acatgaagaa atcattcctt tagaagaatt atatcggatt
    26941 tgccaattcg ttcgtgatat aacaaaagat gatccgtata tgattggccg aatcattgca
    27001 cgtccgtacg tgggtgaacc aggagacttc acacgaacaa gcaatcgcca tgattatgcg
    27061 ttgaatccat tcggacacac agtccttgat tctttgaaag aagcaggaaa ggacgtgatt
    27121 gctgttggaa agatcaacga tattttcaac ggacaaggaa tcactgaatc tgtccgcacg
    27181 aaaagcaata tggatggcgt tgaccagctg ctgaaagtta tgaaaaacga tttttcagga
    27241 atcagcttta ccaatttagt agattttgat gcattatacg gtcatcgtcg ggatgtagtc
    27301 ggctatgcgc atgcgattga agaatttgac ttacgaattc cagaattgct tgaagcgatg
    27361 gaagaagacg acttgctaat gattacagcc gatcacggaa acgatccgac gtttactggt
    27421 accgatcata cgcgagaata tgtaccgtta ttggtttaca gtaaaaaaat gaaagaacaa
    27481 ggggcattgc ctcaaggata ttattcagat atttcagcaa cgattgctga gaactttagt
    27541 gtttcttcga ctgaaaatgg cgaaagcttc ttgaaattat taaaataatc tttttaaata
    27601 ggagaaagca aatgaccaag ttaagcgaga tgttacaaga aacgacccag tttatccttg
    27661 ataaaggagt aaaagaaatt gattttggtt tgattctagg ttcaggatta ggtgaattag
    27721 cagatgaaat cgaagatgct gtaatgattt cttatgatga gatcccgttc tttcctgttt
    27781 cgacagtagt tgggcatgca ggaaagctag tttatgggtc tctggcaggc aagaaagtgt
    27841 tagccatgca agggagattc cactactatg aaggtcattc catgcaaaca gtgacctatc
    27901 cagtacgtgt gatggccgga ctaggggccc attcagtcat tgtgactaat gcatgtggtg
    27961 gtgtcaacga atcatttgta ccaggagatt tgatgctgat taccgatcat atcaatttta
    28021 ctggtgaaaa tcctttgatc ggtccgaatg aagatgcaat gggccctaga tttccagata
    28081 tgagtcaagc ttatacgcct gactatcaag caacagcaaa agcagcagca gaaaaactag
    28141 gtttggatct taaagaaggc gtatatatgg gctattctgg accaacttat gaaacgcctg
    28201 cggagatccg aatgtctcgg acaataggag ccgatgcagt agggatgtcg actgttccag
    28261 aagtcatcgt agcagctcac agcggattaa aagtgttagg aatctcttgt attaccaact
    28321 tagcagcagg tatgcaagcg aatctgagcc atgaagaagt tgtagaaaca actcagagag
    28381 tcaaacaatc ttttaaagca ttggttaaag aaacattgac attattgtaa taggaggaac
    28441 aataaaatga gtgtgcatat tgaagcgaaa gaaggcgaga tcgccgataa gattttactt
    28501 ccgggagatc ctttgcgagc taaatatatt gcggagactt ttttggaaga tccagtttgt
    28561 tacaatcagg tacgcggtat gttaggcttt accggcaaat ataaaggaga acgtatttct
    28621 gttcaaggaa caggaatggg aatgccatca gccaccatct atgcccatga attgatccag
    28681 tcgtatggtg taaagaaatt gattcgagta ggtacatgcg gtgcattgtc aaaagacgtc
    28741 catgttcgtg atttagtact agcacaaggt gcagcgacca gttcttcgat gatcgaaaaa
    28801 aatttccaag cctttcattt tcctccaatc agtgatttca atctattact gaaagcatat
    28861 gagatagcta aagaaaaggg ctatacggtt catgtaggaa atgttctttc ggaagattct
    28921 ttctacaaag atgatttgac agagacgttc caattagctg aacttggcgt tttaggagtg
    28981 gaaatggaag cagcggctct ttattactta ggcgcgaaat accatgtgca gacattaagt
    29041 ttgatgaccg ttagcgacca tttgatcacc ggtgaagaaa caacagctgc agaacgtcaa
    29101 tctacgttca atgaaatgat cgaagtagga ttggaaacag cgatagcaga ataagaagga
    29161 aatgaaaaag ctgccctgca ttaagtaata agaacatcca agcaaaaata gctcctcatg
    29221 tttttgactt ggctggactt attattgcaa atgtaagctt ttgaacaccg tttaccaaga
    29281 ggttgtgaat ctgccgttta actctgagtc acaaggaaca atttcaaaaa acagcttttc
    29341 atgtttgatg aatattgtga ct
//
LOCUS       DAZAOD010000024        27808 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000024 DAZAOD010000000
VERSION     DAZAOD010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.025"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(347..1291)
                     /locus_tag="ACHDPO_001118"
     CDS             complement(347..1291)
                     /locus_tag="ACHDPO_001118"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFN3368760.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1587..2531)
                     /locus_tag="ACHDPO_001119"
     CDS             complement(1587..2531)
                     /locus_tag="ACHDPO_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFN3368761.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLKIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2752..3966
                     /locus_tag="ACHDPO_001120"
     CDS             2752..3966
                     /locus_tag="ACHDPO_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3368762.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3988..6003
                     /locus_tag="ACHDPO_001121"
     CDS             3988..6003
                     /locus_tag="ACHDPO_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFN3368763.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6086..7459)
                     /locus_tag="ACHDPO_001122"
     CDS             complement(6086..7459)
                     /locus_tag="ACHDPO_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFN3368764.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7485..7769)
                     /locus_tag="ACHDPO_001123"
     CDS             complement(7485..7769)
                     /locus_tag="ACHDPO_001123"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3368765.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7771..9786)
                     /locus_tag="ACHDPO_001124"
     CDS             complement(7771..9786)
                     /locus_tag="ACHDPO_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFN3368766.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9965..10270)
                     /locus_tag="ACHDPO_001125"
     CDS             complement(9965..10270)
                     /locus_tag="ACHDPO_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFN3368767.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10359..11390)
                     /locus_tag="ACHDPO_001126"
     CDS             complement(10359..11390)
                     /locus_tag="ACHDPO_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFN3368768.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11597..12472
                     /locus_tag="ACHDPO_001127"
     CDS             11597..12472
                     /locus_tag="ACHDPO_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFN3368769.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12624..13466)
                     /locus_tag="ACHDPO_001128"
     CDS             complement(12624..13466)
                     /locus_tag="ACHDPO_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFN3368770.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13558..15435)
                     /locus_tag="ACHDPO_001129"
     CDS             complement(13558..15435)
                     /locus_tag="ACHDPO_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFN3368771.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15432..16853)
                     /locus_tag="ACHDPO_001130"
     CDS             complement(15432..16853)
                     /locus_tag="ACHDPO_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFN3368772.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16856..20245)
                     /locus_tag="ACHDPO_001131"
     CDS             complement(16856..20245)
                     /locus_tag="ACHDPO_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFN3368773.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20502..21893
                     /locus_tag="ACHDPO_001132"
     CDS             20502..21893
                     /locus_tag="ACHDPO_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3368774.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21966..22613)
                     /locus_tag="ACHDPO_001133"
     CDS             complement(21966..22613)
                     /locus_tag="ACHDPO_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3368775.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22621..23307)
                     /locus_tag="ACHDPO_001134"
     CDS             complement(22621..23307)
                     /locus_tag="ACHDPO_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368776.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23313..24386)
                     /locus_tag="ACHDPO_001135"
     CDS             complement(23313..24386)
                     /locus_tag="ACHDPO_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368777.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24608..25282
                     /locus_tag="ACHDPO_001136"
     CDS             24608..25282
                     /locus_tag="ACHDPO_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFN3368778.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25287..26627
                     /locus_tag="ACHDPO_001137"
     CDS             25287..26627
                     /locus_tag="ACHDPO_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFN3368779.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26776..27762)
                     /locus_tag="ACHDPO_001138"
     CDS             complement(26776..27762)
                     /locus_tag="ACHDPO_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFN3368780.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8106 a         5253 c         5044 g         9405 t
ORIGIN      
        1 ataaaaaaat tttgcagttt ttcttacttt ttttgtcgtt taattgaatg ataaaaacca
       61 gtttctttat tcagttaatc aaatatgaac gaattagata tgaatcattg tatttgccgt
      121 tgcggaagga ttttttaatt aaccacagat aaacattgat aacgattcgc ttattgtaat
      181 caacagatta aatttcatat gttcatatgt acggatacat tttcggaccg attaatttta
      241 accattctat ttatttgctt acctattaga tatcaataaa aaactgctta acagctattt
      301 cagctgttaa gcagttttag gatttttagt tcatattcat tgtttcttat aatacagtgt
      361 tcaatacttc tcttaaagca cttgttgatt tgctgaacat tgctttttct tcttcgttga
      421 ttgataattc aacaacttca cgaacaccat tttcgtcaac gattgatggc acacctgtaa
      481 agatatcttt ttcgtcgtat tcaccagtta aataagcaga tacaggcaat acagcttgtt
      541 cgttattcaa gatagctttt acgatacgtg cagtactcat accaatacca tagtaagttg
      601 cttttttacg atcaatgatc tcataagcag cattacggac tttatcagca atcacatcta
      661 attcatcttg ggcaatacga tggtcttttt ctacaatttc aaacactggt ttaccaccga
      721 cagttgtatg tgaccatgca gcaacttctg aatcaccatg ttcacctaag atatagccgt
      781 ggacgctgcg tgggtcaact tttaatttca atgcgatttc tttacggaaa cgagttgtat
      841 ccaatgttgt tccagtaccg ataacacgtg atgttggcag accagattcg ttccaagcga
      901 tatatgtcaa aatatctact gggtttgaag caacaacgat aataccgtcg aatcctgatc
      961 ccatgatttc ttttacgatt tggcgcatga ttgacgcatt tgttttaact aaatctaaac
     1021 gagattgacc aggtttttgg ttgataccag ctgtgataac aacgatatca gcatctttac
     1081 attcttcata gccacctgac catacagcca cattttcatc gccccaagcc ataccatcta
     1141 aaaggtccaa tgcttcccct tctgcttttt cttgattcac atcgatcaat actaattcat
     1201 tagagattcc ttggttgatc attgcataag cgatacttgt tccaacaaaa cctgtaccga
     1261 cgattactac tttacgactt gtttttttca tgaataaaca gctccttttc ataactattt
     1321 gttactttca tgaaaagtat agtcttgttt attcatttta tcaacatgtt aattataata
     1381 gttgttatta taatttttga tggaaacgaa ttcctgaata cgcataacag ataaatgaca
     1441 aatgtttaca cctatatccc ctgataatac aaccaaaagt ttagaactga aaataaatcc
     1501 aaaaaaattc gctgcaacga tataataaga cagcaatcgc acctaaaaca attttccttc
     1561 atatgcttta gtgaaagatt ttcttcttaa tgtttatttc tccattcatt gggagtacat
     1621 gttgaatact tcttgaataa tttgaataaa gaagtcgttt gtttatatcc gatacgatta
     1681 gcgatttctt ccaacgaaaa actcgtttct tgaatcagtt ccaacgcaaa gtcgaatttt
     1741 ttctttagaa ccagttcttg aaaggaagca tcaaaataca ttttcaattt attactaaga
     1801 tagaccggat tgtagccaaa atgagctgct gtttctttta acgtacaaga agtaaaatgc
     1861 ttatcgatat aatctaatac tctaagcatc tcattttctg cgcatccatc tgctgatgaa
     1921 aagctttgtt gttctaataa atgagtcaat tcgatcagta atagtgatgt atagagattt
     1981 aacgaacgga tcttatgact gtatgtatca aaataaatca acagcatatt ttcaatcaaa
     2041 tgcgtcaaac gacttgtttt tccgccgcga aaatgaatga attgtgtatg ttcccctttt
     2101 tcttttgatg catttatcaa aaaagaagaa agtagattat ttgtgcttgc caaatgattc
     2161 aatatctctg tagataaggt ttcttctttt aataagatgt tgattaaaat atcctcttgc
     2221 cctgtgtatt cgattctttg agtagcttct ttatcaatga tcaccacgtc actttcttcc
     2281 atctctatcc tttctccatt aataattttt aaacatgtac cgctatacat ataattgatt
     2341 tcaacaaaat catgtgtatg ctcgggaact tccgcatatc gacggtgttt actgatatga
     2401 atatttccct gttgaaatag atcccctcgg tggatttttg gcggtgtctg aagatggtaa
     2461 gctaagttta aatcattgat attcattcct tgttcacgct gcagagtttc gattgattct
     2521 tcgttacgca aaaaaaatgt ctaattcagc tagttccaat tgactccctc ctttttgtaa
     2581 gcggtttctt tcgcttatta gttcacgctg tactgctatt atatgcaaag ctatttttgg
     2641 tttcataaag actttctatg gttgggacat gaacttcctg tgattccgct attgagagaa
     2701 taaccacttc atactatatt tttgataagc gcttacaaaa atgaaaggaa catgcttatg
     2761 aataaaaaga tgatgaaatt ttctctgctg tcagtctctc ttattttgac ttctgctggt
     2821 gcagtcacgt ctgcaattcc cagtatgtca gctacttatg ccacgcgttc tttatctgct
     2881 gttgaattat taacgactgc tccctctttt atggtcacta tttttgtttt gattagtagt
     2941 tttattgcta ggaaaatcgg acaaaaacaa actgtgatca tcggattagt gattgcatcg
     3001 atttgtggta tcctccccct cttctcacaa agttacagta ttgtcttagc ttcaagagct
     3061 ggactaggta ttggctttgg attgatcaat tctttggcag tcagcatgat tgctgccttt
     3121 tatcacggag atgaacgagc ctctatgatt ggttttcaaa gtgcatttca aggatttggt
     3181 gcagctttaa tgacatttgt tgcaggacag ctagtacagt tcggttggca atataccttt
     3241 ttagtctacg ccatcagctt acctattctt gtcttgtttg ttttgtttgt tcctacacct
     3301 gaaacaactg aacttcaatc gcatggcaca gccccaacaa gacaagtaat caaaacgaat
     3361 cctaaaatga ttagttatgg tatttttctc ttgctggtca tcgtggtata taatgctgta
     3421 tcgattaaat tagccacagt cctgacgact tattctctag gaaacgaaac taatgcagcg
     3481 aatatcttaa caatcatgca attggcaagt atggctgccg gagtttgttt tggctggctt
     3541 cagacaaaag cacatcgcta tatgcttaca ctttctttac tactgatggg aatcggcttt
     3601 gtattgattg ccactgtgat aaacctgtat gtgattgggt ttggtgcgat cctaacagga
     3661 atttcttttt cgttattcat tccttactta ttcaaccaag taagtatcca agcgcccaag
     3721 tacgcggaga gtttcaatac ttcaatctta ttggttggcg ctaatttagg tactttcatt
     3781 gcaccatatg gtttgctctt tctctctttt gcttctcttg ggagtaaaac acttgctgtt
     3841 ttcgtcaatg gcagtatctt gctgttgatt agcgcgctta ttagccttct agtagtacac
     3901 aggacgaata gaaagacagt gataagagta gatgaagaaa taaaagaaca attgacaaca
     3961 aaataaattt gatggaggtc gtgtaaaatg acaaatgaaa aacataaaga tagatggctt
     4021 tggtatcctg gagactttga gatccgccat ggactgctac aaaatttcca acgggaagaa
     4081 cgaggttttg actggccagc gtactggtac atggatgatt gccatcggaa cgtcaagttt
     4141 aagagatatt actttcttga tcaaccttcc atgtttaaag tgacgatcca aggagttggg
     4201 tatgtagaaa ttaatggaca aaaacatcca tgtggaaaat ggctgacttg tccagctggt
     4261 aaagcaaaaa ttcgtatctt tgtaggacat acatcagggc taccagcgat gtttatcgag
     4321 ggagacgaag taaaatcaga tattggctgg acagcaagta attttattga agaatatcca
     4381 gctggctgga gtccgcttta tgtcgatatc gcaaaagatc caaatcaaat ctattatcaa
     4441 aaagaatgcg tccatccagt cactgaaacg gagattggcg gaggaatctt attcgatttt
     4501 gggcgagcag tgaatggctg tgtagaacta atatctctgg atgaccatat cgaatctatc
     4561 actctatgtt atggagagtc cgatgtagaa gctatggata tcgattattg ctactataag
     4621 caaataggaa tgacaagaaa aatgaaagct cgtaaacgcg cttttcgcta tttgtttata
     4681 ccagaggttt ctactggaat ggttcaactt caagtttttc atgaattttt atctctttcg
     4741 aaacaagctg ctttttcaag cgattcttct ttactgaatc agatctggtc agtatcagaa
     4801 gaagccttca agttatgtag tgatttgttt tttatcgacg gtatcaaacg agatcgctgg
     4861 atttggtctg gagatgcgta tcaatcattc atgatcaatc aatatctttt ttttgacgag
     4921 gaaatcaata aacgaacgat attagcatta agaggacaaa atgaaatcaa gcagcatatg
     4981 aatactatcg ttgactattc gatcttgtgg ttgattggta tcgaaaacca ctatatgatg
     5041 acgaaagact atgaattttt acgcatcgtc taccctaaga tgcaatcatt aatgagatac
     5101 ttgatggagc aaacgaatga attagggttt atttatggga gagcaaaaga ttggatattt
     5161 attgattggt ctgaaatgga taaagaagga acgcttgctg cagaacaagt cttattactg
     5221 aaagcctatc attccatgat cacttgcgga gatatcttag ctgaaacata tggagagaac
     5281 gaaaattatc atactcatct ctatcaagaa aaatatcaac tattgaaaca aaacctattt
     5341 gactactttt gggatgaaga acttggcgct tttatcgatt gctatgaatc tgggagaaga
     5401 aatgtgacgc gtcatgcgaa tattttcgct gttttattcg attttgctaa caaagaccaa
     5461 cagcaatcga tcttaaagaa tgtcttattg aatgacacta tcacacagat tactactcca
     5521 tatttcaaat tctatgaaca agatgcttta tgcaaactcg gacagacgaa tatcgtctac
     5581 caaacgattc ttgattattg gggagggatg ttatctcatg atgcggtaac tttctgggaa
     5641 gaatacgacc ctactcaaac aggaaatgaa aagtacagta tgtatggaga tccttatgga
     5701 aaaagcttat gccatgcatg gggagcaagc ccaatctatc ttttaggacg ctattttatc
     5761 ggtttgtatc caacaaagcc aggttatgaa gaatttatga tacaacctaa tctagattca
     5821 tttgaaacac tgaattgtac gctacctatc aaagatggaa agatttcgct tgaaaaaaca
     5881 aaagataaga tcgtgattac ttctgataga acaggcggaa cagtgaaaat gaatggtaaa
     5941 agttatcctc ttctagcaaa acagccactt gtcttaacaa gctattcaaa aataaatgca
     6001 taaaacaaaa aactgcttgc gacatatcag aagactttaa atcttcttct gatattgtcc
     6061 aagcaatttt tattttgaag tttgcttaat tctgttcttt agaaacaatg tttgttcttt
     6121 ttccggcaaa aagaaagcta gataatacga caagtaaaaa gaaagcgatg attccaactg
     6181 tcaaggctat ttgaccgtat tctcctagtt tcccaagtac aagtcctggt actagataat
     6241 cagtatcggc aaatgtagaa gaagcgattt taagatctcc taatactgga aggataaata
     6301 atggcagcca actaatcaat aagctattga aagcagaacc taataccgcc cctcttctac
     6361 cgccagtcga gttgccgaag acaccagaag cagctccgca gaagaaatgt cctactaccc
     6421 caggaatgat aactgtagtt tgcaagccta tcatagcaaa catggatagt gttcctacaa
     6481 agaagctaac aaaaaagcca attaatacag cattaggtgc atatggaaaa acgataggaa
     6541 catctaatgc tggtttagaa tcgggtacga gttttttagc aatcccttgg aatgctggaa
     6601 cgatttctgc caacaccatt cgaacccctt gaaggacgat aacaaaccca gctgtgaatg
     6661 ttccagcttg gatcagtgca aagattacag cgttgtctcc attgcttagt tctctttcaa
     6721 caaatccagg accagctaac aaagcaagtg cgacatatac gatcgacatc aagagcatga
     6781 tcgatacagt agaatctcgc aaaaagctga aacttttagg aatctttatg tcctctgtag
     6841 aacggtcttt gtttccaaaa aactttccga tccatccact agaagcataa ccgatatttc
     6901 cggtatgccc taacgcaact tgattgtttc cagtgatgtt cttcataaac ggttgacaaa
     6961 gagcaggcgt aatagttaat agtgttcctt cgaagacccc gcctaataag atcatccaca
     7021 aatttgcagt aaaccccgcg cttactaaaa tgactgctgt tagacaagaa acataaagca
     7081 ttgcttgacc tgtaagaaaa atgaatttat atcttgtgaa tctagcaagt aaaatattca
     7141 cgatcatccc tactagcatg atcaaagcag taggtgtacc gtattgttgc aaagcaatcg
     7201 ccactactgc ttcattgcta ggaactactc cttgagtatg cagagctgtt tggaacatcg
     7261 aagcaaaagg ggttagtgaa ttactgatta aaccagcacc gccgatcagt actaggaatc
     7321 cgacaaatgt tttgatagtt ccttggatca cttctgaaaa tttcttcttc tgaagaacga
     7381 gaccaagcag tgcaatcaaa gaaacgagga tggagggctg actgacgatt gacacaaaca
     7441 aattcaacaa tttatccatt gatagttcct cccttgaatc atttttattc ttttgacaag
     7501 atcttcgtta ctttttcttt tacttcttcg ctgtcaatga tcgattgcaa aggtacgagc
     7561 ttttcatcag gtatagaagt tagcgtatct ttcaaagaat gctcaatgaa gaaataatca
     7621 gccatatcgc tagatacact tccaacatcc gtatgactta cttcaaactc gtccacatct
     7681 gctccaagat ctgcaagtgc ttgtttgatg ttcatctcta ccataaaact tgttcctaat
     7741 ccactttgac atactgcaaa aattttcata tcattcgtct ccttttctta tgatcgctaa
     7801 tatttcttct tttgttgatg cgtgtaataa atcttgaaga ttttgtttat tagaaagtag
     7861 ctttgttaaa tttgccaaag cccgaagatg tgcctcatta tcgatagcag ctaaacagat
     7921 gaacaaacta atgggatggg ctggattatc aagcagatcc acaggttgtt gaagtttcag
     7981 caaagacatc cctacttcgt ttacgccatc ttctggacga gcatgaggta atgcgatgtg
     8041 atcgccaata tggataaacg caccatactg ctccacgcgc tcgatcatag ctttgatata
     8101 actttcttct attttatttt ctgataatag cggctgtgcg gcaaatgtga ttgcttcttg
     8161 ccagtttttt ggttgatccg ataattggat catttcttct gttaataatt cagatagcat
     8221 aggacgttga tcctccttct tttctaaaag tttgttcatt ttacgattta atacttgata
     8281 gagcttttct tcgtctacgc cttcttttaa ttcgatataa ggcagtagcg ccgacaacaa
     8341 ttcttgggca gaaggcattg aaaatcctgg tatcagccaa tctctttgta cttgattgat
     8401 cagctgattt ttttccaagt cagtcatgat tggatgcaga acatagagag actttttctt
     8461 atcagtaagt gtgagaggta cagtagaaaa aataatatcg taagaagttt cgtcaacctc
     8521 gtgtaagcgg tcagctgaat tagtctctgt aaaaaagatc atcgggaata attgctgaag
     8581 ttcacttttt aagatcaatg aagagctaat gccacttgga cagacgatca cggctcttat
     8641 ttttctattt ctttcttctg cgtccgcttt tctgatctct ccgccaaata gtatagtgaa
     8701 aaaaccaatc tcttcttcag ggatgctctt ccctattcgt ctttctaacg gaagtaatgc
     8761 ttttcttgtc atttcgtaga tggaagcata ttgatgctta atttgatcga tcatcacatt
     8821 aggtaaataa aaagaatagg aaatacgaaa ataggcaggg accaagtgat aaaagacatt
     8881 catcaataat tcacgaaacg aagcaaattc tacggccatc aggaattcca tgcgatggat
     8941 gacttctgaa gaacattcca gcaaaaaatc aagtgcaggc tcctggacat ctccttcaac
     9001 gatcgatgct aagcaaagag agaaaaatat aatctccgaa ttttgatgtt cggaatagcc
     9061 aaggccagtc aatacttgtc gactaatgtc agtgactgca agagaagcca acagttcagc
     9121 atcttttacc agttccatgg atgtttttcc aattcgaatg gttgtcaaac tcaaataata
     9181 agctaattca tccattcgat ttggtgcgaa tcgaagatct gatagtgaaa tcgttttatc
     9241 tagcaaatct ctaactttgg cgtaataatc aatggaaagg gttgcggtta aatacgtgag
     9301 cccaaatctt ccagcaagtg actgcatcaa acgagcagtg cgattttttg cttctcttct
     9361 taatattgct tctgacccta gcagcctaaa accagttttc ctagtatacg acagctgaca
     9421 atcttccact tctaattcat ttcttatctt tttgatatct gacaggactg tccctttaga
     9481 aacctgaaga aaatcttgaa aatgaaaaac agaaacagac gttgcagtcg aataaaccat
     9541 caaataaaga agatctcttc gctcttgttc ggtatacaca gcttcaaatc gagtaatatc
     9601 caaaaatttt tctgcccagt cgattgctcg gaatttcttt atacggatac gggtatcatc
     9661 cacatattcg gcaaaaggag ttaattgttt gatcgcctcg cttgtattta cttcgatgat
     9721 ctctgctgct ttttctagac tgatttctct tggtgttttc aggagataac taattttgta
     9781 gttcacagcg ctgttcacct cctacttata ttctagtatg gtagcgcttt taaatcgagg
     9841 ggtgtttggt acaacttaca gttggatttt ttttacgact gtaccgaacg atttctatcg
     9901 aatggataca gaaaaaaagc aggtgaccaa atgtctcctg cttttatgaa ttgatttcgt
     9961 ccgatcaatg atgatcatgt ttattttttg aggtcagttc ttcaaatttt tctttgacat
    10021 cttcaaccgc tttttcgata tctttttcaa agtgattggg ctcattaggc tttgtttcct
    10081 cttctacaga atttgaacca gataaagctg tttctttatt ttctgtttca ccagagtttg
    10141 tgccagctaa tgattcttct ttgtcttctg tttcaccaga attagttcct gctaaagcca
    10201 cttcttcttc tgttttaggg gccattgaac ctcttaatcg tttgtgtttt tcaccgtcat
    10261 aatttgtcat gttggttcct cctagtagtt ctatactttt tcatcgtaca ataagacagt
    10321 ttatgcgtca aaaaacaaac ccgattctta caaatatgtc atatttttcc ttctgattct
    10381 tgaatgcttt tgattccttc ttccaaaatt ttcatttgta agattgtttc ttcatctttg
    10441 atgacttttt ctgcgccatt aactaatgtc tcgtaaatcc cttcgtagac acggctgtaa
    10501 tcaccaacct cggaaattac tttttcttca tgataactcc cttgttcatc tatataggtc
    10561 aatacaccat aatgttcggg caaatcgata ccaaagtctt catgatcagg catgtaaaac
    10621 attttcagat gttcttcttg tcgatctttt gtttgtttca cgaacatccc tttttttccg
    10681 taaacgacga aacttggacg ttctttgatg cggaaataac tggattttat cgaaattttc
    10741 atatttccat agaaaaaatc cagatcgaag taatcattca ttcgtccttt ccctaaaagt
    10801 tgacgtacat catagctgat atcatctggt tcgccgaaat aagaaagaac ttgatctact
    10861 gtatgacaag catgtccata taaatagctg ttcgcagtag aaaattcatg cgtattttct
    10921 ggtacttccg gtctgaaata atcataatgc atttctactt ctaaaatatc ccctaatttt
    10981 ccgctttcga ttactttttg gactgtcaag aagtcagaat cgaaccgtct gttttggtaa
    11041 cattggataa atagaccttt ttcttttgct aatgcaaata actcttctgc ttcctttgac
    11101 gtttctgcaa aaggtttctc tactagtaca ttcttaccat gttcgagtgc catttttcca
    11161 tattcataat gaaattgact aggtgtagtg atgacaacta attggatctc aggatcatcc
    11221 caaagatcag acagctgatc agtatattcg atgtcttcga atgttttcca cactggttca
    11281 gatggggaaa aaattttttt gatattgatt ttgttcgtaa gttttcttga aaaaggcaaa
    11341 tgatagcgat ttgtactctt tccattgcca agataagcga ttgtaagcat gagtggtgcc
    11401 tccttttatt gatgttttca gtatatccta gaaaagcgca gaaagtattt ataatagcta
    11461 ttctggtaaa aaagttcaga aaaacacttg ttatcattcg gtttggtgaa attaatgttc
    11521 aaagtaagga taaaaatcaa aaagatagta gcggaaccaa gtgtttatca gtaagataga
    11581 atttggaggt cagatcatgc ttattgaaga aaaactaaca aaacaagagt tgtttaccac
    11641 gacagagaaa cggattgtcg attacatccg taggaatatc gaagctgcag tctacatgac
    11701 gattgaagaa ttagcaaaag ctacgtatac ttcccattca gctatcattc gtttatgcaa
    11761 aaaaatggga ttcagcggat ttaaagaatt ccgtttcgag ctggggcggg aagttcatca
    11821 attgattgct cagttcaatc aaacgattga tcctaatttt cctttttcaa gtgaagatag
    11881 cactcagcaa attgcaaaga aaatggcgga tttatcgatc cagtcaataa aaaaagcaca
    11941 attgcagatt gaacatgaag atttagatca aatcggtaaa gtattgaaca aggcacagcg
    12001 aatctttctt tttgcaaaag gtgattctca aatcacggca aggaaattcc agaataaaat
    12061 ggtcaagttg aataagtttt tgatcatggc tgaagaatac agtgattctt cttggaatgc
    12121 agccaatttg actagcgagg attgcgccat ttttattagc tacagcggtc gcatccatca
    12181 ttatgaacga ataatgacct atttgaagca tgtagaggcc cctaccttgc tgattaccgg
    12241 aaatcagcat tcagaaatgg ccaaacaggc tgatatgtgt cttgttatat cgcaggagga
    12301 atatgatttt gctaaagtag cgactttctc ctctcaaatt gccttcgatt acgtattaaa
    12361 tacgttattc tcagtgatat attctcaaaa ttttgaagag aatatccgca acttgaaaaa
    12421 caaacaagaa ttgatgcaaa aaggccttct taaagaatat cggaaaactt aagaaaagat
    12481 cctcatttag taataagaaa gatagtgttt gataggctct ctttgatatc atcataaaaa
    12541 caggctgaag ttttcttttt caaacctcag cctgtttgtt tacggaacga ttcgaataga
    12601 tatattatag aaatgaggaa tagctaactt ctgtttctta ttttgaacga ttgacgaaaa
    12661 agatatataa gaaggaggaa aatcagtata catgcagcta acaatccata caggaaaaat
    12721 cgtttgttct cggatacttt ctgtacttct ttttgaactt cttttgcatg ataaggaacc
    12781 cggtgccctc tgacaagtaa gcgatgactg ttgaccatat aaggtgtaca agttaggagt
    12841 gtcacgaaat cctgcccttt ttcgattctc agatcttttg tatcagtcgg ttctaccgtc
    12901 ttgatctgat cgacttgata agcgagtgtc cgtccattga tttcgatata gaaagaatca
    12961 cctaaagtca gtttcggtaa gtctgtgaac aactttgctt gaggcagtcc tcgatggctg
    13021 gaaataacgg catgtgtatt ttctcccccc gtaggataag acgttccttc caataatgag
    13081 gcaccttttt ctagcagcac agtattcgtt tcatcaaaaa ttggcaaatg gacattgatc
    13141 tcagggatcg tcaaaatacc gatcgtatgt ttctcaaaat aggttctatc ctttttcgca
    13201 ggttcttttt tcttagtaaa gggatctgca cctggatttc caccttcttt tgctaattgc
    13261 tggtttttct ttgtcatgtt ttcttggatt ttagccatga cttcttcatt ttctttgacc
    13321 gcttgttgct gataatgaga gatgatctgc tgatccagat aattattcag cgcgtcgcta
    13381 acaaatggat aagctagtat ccctattcct gagagaagca agaaaagcat cagcagatct
    13441 agaagtttcc ttttctttgg tttcatttgt gttctccttg tgatgactgt ttgataataa
    13501 aagaaaaagg agcatttgcg taatccgctg ctcctttttc caattcttgc aaaaagacta
    13561 aatctgactg tgcttgcgtc tagcaaagta cagtccagca atcagtagaa ggactactcc
    13621 tgcaccgata tacacataga ttcccttacc gcctgttgaa ggaagtgtac ctttgtgttt
    13681 atttggtatt ttttcaggag aaatcaactg tcctgctgtt acataagatt gttcatcgat
    13741 agtaaatgct acacggtttg ttaatggaac atatttttct ggcgctttcg tttcttccag
    13801 atagtacgtg ccatatttta gacctgtcac atcgattaaa ccgttacttg tggttgtaaa
    13861 aaccgttgct gattctttcg ccgataccca gctgacggct tttgtggatg ggtcgatcga
    13921 taaatatttc gctgtgtcac tatcttgatc acgaacgacg aattctgctc cagcaagtgt
    13981 ttggtctgat gtaacgtcac catctacttt aacaaatcgt ttgcccccag taacgacatc
    14041 gactgacggt ggtgtttgat catttgtatg cccgttatcg acatttgctt ggttagaaaa
    14101 tcctttggtt ggatctgctt tttcgttcaa atgcatatag taaacgaatt tcaatgtacc
    14161 gccaggagtt aatgaaggaa tataattcgg atcaactgaa accgtgaatc cgtctgtttg
    14221 ctcagtgaca gaataattta ctgggtcgat ttctttattt ccatcatata aggcataagc
    14281 atacgttcct gaagaatcat tatcaaatgt taaagcagcg tcatgagtat cgataagttt
    14341 gaatgttgtg tacttgtttt gcgttccttc tttatcagcg atacctaatg ggatattgac
    14401 agaaatctca tattgaattt tttcaccgat tgcgacatct tttccattca attgaggtgt
    14461 tgttttatca actttagacg tatcattttt gatggtcttt tctactggtg tttggctatt
    14521 tgccaggatc tcaaaaggcg tgattgtttg cttttcaatc atttccgcat tatcaggagc
    14581 ttttacttct tctaaattat attttccaac ttctaaatga ttaacgatca actggccttt
    14641 ttcaatagat gcctcggcaa agtcattgtt gccgatgtca taagaatgac cagtaatgaa
    14701 atgtttggct ttggtttgat cagttgtcca agtgtacaat ccatctgtga cactttggat
    14761 gtattttttg acgcttggtg ttccttcttc tttagaaata ataaattctg ctccatttag
    14821 tgcttcgttt tcggcagtac cgatttttgt aactttcaac gttccatcat taccgactgt
    14881 atttttaggg tagagatgga tagtatctag ttcttctgtc ccgtatttat aagagccatc
    14941 tgcttgtttg atcatctcat atacagggaa agctaaaacc atgtttgcgg cagctgacac
    15001 tccgtctttt ggttcttctt tgatcgtgta gactgcatct ttcccatttt gttttttagg
    15061 taaagataaa gtgacatttc catcagcatc tgtcgttcct gaagcaactg gtgtaccagg
    15121 agtcaaagac tggactgctt gttttgctgc atccacggac gctcctttat ctcgttgcgc
    15181 ataaaattct tgagtgacgt tataaactga aaatgaaata tcggctaatc cttggtattg
    15241 atcgaattcg ctcatttctt tcccgctgtt ttggattaaa ggatcgggta aatcagtcat
    15301 tttcttttta tgaaggatga cttgagctgc tgtctcctct gcaaacactt tttttgcgcc
    15361 gaagctgttt gtgagtaatg gtaaaataag gaaaaggact cctaacataa cgtttatttt
    15421 tttatgattt ttcatttttt cactcctgtt ctttttttga taaacaacca gattgcaaag
    15481 cttgcgaata ccataccaac aacgcctaaa agtgtatttt tcgtttcgtt tgtttttgga
    15541 agaaatggac ggctattttc ttttttattg actactttca atatactgtc cgcctcttta
    15601 tcctcagaaa gaaaagttga aatggtaaac ggaatttctg tttcacttaa aatataacca
    15661 gaaggtgctt cgatctcttt taatcgataa cttcctgttt tcaacccgga aattgaaaaa
    15721 gcgccatttt tatcggaaat caggtgaagc gcatctgatt cgttctttgt ccacttgtat
    15781 ccgttggctg tttgctggag gtaatttcct gctttgtttt taataaggaa tactgcgcca
    15841 gctaatcgtt tatctggttt atttgtctcg attttgacaa attgcttact ccctgtatat
    15901 acagagactt tctttgtact gacaccaaaa ccaaaatcca gtgttccgtt gttgttgatt
    15961 tccttgttcg cctgtgctgt actgcttagc tgcatctgat aagaaatggt cagttttttt
    16021 ccagcatatt tttccaacga agggatcgaa aataaaacat caaatccgtg aggtttcttg
    16081 tgtatgacaa agccttctgt cagcttttct ccattcgatg aaatcgttaa actattaggt
    16141 aaaaacgtta atgcttcatc cgcactatct gacaattcga acttttgata gtcaaggata
    16201 tttacaggaa ttgtcgtatg caaggaataa gtgatttttt caccaatcgt aaaatcattt
    16261 ctaggctctt ctaatacctt ctcaaaaggt ggatcagggt agtcgttttc ttcattttta
    16321 ggatacaaat ggatagttga aagtttttga ttgttttgtc catgtacagg aagaacaact
    16381 accatattct ctgccttttc tttgacgact tctggtactt tggattcaat gaaaagatac
    16441 gctttatctc ttttttcttg atctttagcg gccagagaaa aagaagcgat accatcttcg
    16501 ttgttaagag ttgtagttgt tgcttctgcg gtaaacatac cggaagacgc accgtttttt
    16561 gcgatctctg cttgtgcttc ttctaccgtt ttgccctttt cccgtagatg gtaaaaagaa
    16621 tctgtgacat cataaacttg gaatgtgaca ccatttaatc ctcgatacgt ttgtaataaa
    16681 gctttttctt gtccgtcatt tggatgattt ttcggcagtt gcccgtttgg gaaaagcaat
    16741 ttgtgtaaag taatctgaac catttctgtt tctgtttctg ttgctacctg agtaaaagct
    16801 ggtttaaata gtaacaagaa gagacacata ctaagccaac caagtttttt catatttagc
    16861 tgccccctct ttcttttttc aaaaaaagat accaaataga aaacgcacaa ccaatcatcc
    16921 ctactagata gattcctaaa cggccaattc ctcccgtttc aggtaatggt acttttgcct
    16981 gattcgtgat gtctaaagaa atctggttgt ttttggctcc tggtgacaga acagattcat
    17041 gatcttgtcc atccacttga attgacccat cttcgtgtat aactatagta actggctctt
    17101 ttagaccttg gtatccttct ggtgtaaaag tttcggtcag cgtataagtt ccaggtttta
    17161 aattttcgaa tagaaaggta tctgtttctt gtccatcttt tggcgattct aagtccattt
    17221 ctggtccctg cagtctgaat tttgctcctt ttaatgtctg tccgttgtct tcttttttgt
    17281 gtaccgttag atcaaacgct tttagtcgat tttgatgagt gagcgtccat acattatttg
    17341 tcatctcggt attttttccc gtgtaaatga tttttccata tttatcgatt tggaattcat
    17401 aatttcccgg cgaagtatca tatccggcag gaccagctgt ttcaacgact cgatatttac
    17461 caggtgtgag tgaatcaaaa ctggcaagac ctttttcatt cgttgtttgg ctgtcaattg
    17521 gctgataagt accatttgct tcttttttct gtagggaaaa tgctgctcct ttaagattta
    17581 tctctttgtc cgtcccttgc atcgcatact tacgtactgc tacaggaact tcaacaaaag
    17641 gattttcaat agtcaactgg atcgtatcat cggaagtagt gactgttttt ccatcaatgg
    17701 ttaccgtacc atcagaagcg atcttgattt cccaagtagt ctttttgctt aatccatgcc
    17761 cttctggagc ttttgtttct gtcagcgtat aggtcatttc tttttgcaat ttgacatttt
    17821 ctggaagaga ataggttccg tcgccatgat ctgttagtaa agtatcaata gaatctcctg
    17881 ttaatttgaa aacagcgcca ataagatcct tttcacctgt agaggaattt ttcgttattt
    17941 tcaagtttaa cggtgtgaat tgtttagtat ttttccatgt cattgcatct atttgttgag
    18001 aatcgtatcc tggtacaggt aattctttga ttgtttggta actgaatgct tgaccttgat
    18061 tattgtattg aggtagtgat aatatctctt gataactttc tccgctattt gcagataatt
    18121 tgtcaatgtc tgcacgttcc cacgtatttg ttgtatcttt agctggttta atgattcgaa
    18181 tatatccgtt tttccaagct gcagcatttg tcgtatgttc ccgttgaatc tcaaaagtaa
    18241 cttgatctgg acgatcagct agattgttgt caaattcttc ccataacttt ttgatgtgaa
    18301 gactgactcc gggagcttta gcagatggta taccgaattc agctaattca ttggtatcaa
    18361 tgtttggctg gaaagttgtc ctgccgttca tttgatacca gaaatttgga tggaagtcct
    18421 cattttctgt ttggattctc acttggtaat ggatttggat ttcttggtct tttcctaaat
    18481 agatctgatt gctcttgatg gtatttcctt ctatggaaat agatggagtg accgttgtag
    18541 gacttgtccc cacactcttg actgaaagtg taccaggctg ataaatgaat ggttctgcga
    18601 ttggatcatt tatttgtcca ttgcttacag ttgctgagat ctgtacagct tttttggcta
    18661 ggtattcaga gatatctgtt gcatgatcag ctgattcata gtaaagatcg cctttttcat
    18721 ctgatgaaac catttgtcgc atacgagact ctacttctgc ttttgagaga ccagctgccg
    18781 gatcgctttg aagttggatg ccaagaccat gtatttcgat tcctcgttct ttgagtgcca
    18841 tcgcttctcc gatggttgcg ataaacgtac tgtcgattct tctggataga ttgttttggt
    18901 caggtgcatc atagattctt gagattagag aagtatttcc cggccgatct tgcgtattag
    18961 aaaactgagt tccgtaataa ttgctgcttg attgtgcgtg tacccgctgt actttatagg
    19021 aaaatgttgg tacaccatcc gtcagcaaaa cgatcacttt tttatgtcca tttggaacgg
    19081 atagcatgct tcctgcatct cttagtgctt tttgtgtaaa agtaccacca tttgtccgtg
    19141 aaggtgtaat ggattttact tgatttttca ctgaatcaaa tgaacccatc tgtactgcac
    19201 cgttactgta gctatatcct tcgcttgagt agccgacata tcccatattg attttgtctg
    19261 tgataccgct atctgctaaa gtatcgacaa aacgatcgac accaatcttt acttcaccga
    19321 tccgattatt gtcgttcata cttcctgacc agtctacgac caatacgaga tcaagaggcg
    19381 tgatatcttt ttgtacattt ccacgagcat tcaaataaac atcaaacaat ccgggtgtac
    19441 ttgtttcctt tgcatacttt cgtatcgcat agtctgcttg attaccggtt cctccatatt
    19501 cgatatacga atgggtccga tcattaggat ctccattcca agaatttata ccatcccatt
    19561 gatttgttcc gtttttattg ccttgatgat caagaacatt tgtatttcct gtaggttgcc
    19621 aactggcttt aggataagtg ccctgatcat ctgttgtata ttctgtagga atcgtttgat
    19681 tagatggcac actcacagct ggcaaggata atgtaggcaa tgtaaatggg ctgacagaat
    19741 tttcgttttc ttttgatgat tcttcttcta tttcgtctgg ctttggtact gacacatctg
    19801 tatctttctt attttctgtc tcatcaataa tgtcatattc tttattatcg acgatcagct
    19861 tgtttgcctg gctgtggtaa agtgctggat cgattggaaa actcagatcg atagtttgtt
    19921 tagtgtttga tgagatttcc aacgtaattt tcccgctatt tacctgataa gcatagccat
    19981 ctccttcttt tctttccaca tcacttaagt aattttcgac tagaccaatt tctttttcta
    20041 tcttttcagc actggtgtta ttcgcattta gcttgatgtt cagtgctttt tttccagact
    20101 gatccgaaat gacttcagct gaaattgttt ctaaaactgt tggatcatct gtagtgtctg
    20161 ctattgcaga taatggcaca aagtttgata aactcaatat tatcagcatg aaaataactt
    20221 tcagtttctt ccctgtggtc gtcatttttc ccctcctttt tctttttttc tgttttgacg
    20281 tgaatagtga aaattattaa aataaacagg cgttacataa ttttatttat tttaatatga
    20341 taattattat acgaagggcg ctaaagggaa tcacaccaat tttcatacca attggtttca
    20401 tttatgaagt tgattccttc gattaatgag cgtttcattg aaagaaaagg gttgagggag
    20461 aaaaacatat gatcaggttg ttggaaggaa actatagaaa gatggaaaaa atcattcgaa
    20521 ttctgtccat ttctgacaag tggatgacta aaaaagaact tgccaaacga attggtagtt
    20581 cagaatctac atttgtaagg tatatcgaag agatcaaaat ccgctgggga acggatgtaa
    20641 cgattcaatc ttcacaaaaa ttggggtatc gtcttgaaca tttgaatgta ccagcttatt
    20701 taaatgttct gatggaaatg tcgcaaagtt ctacaaacag tcgtttatta aatgagatta
    20761 ttgtcaatcc gggtaaaacg attgagtatt attgtgaaaa aatttccatc agccggtctt
    20821 cttttacacg taagttgaaa caatgcaatc aaattttaga aagctattta ttaaaagtga
    20881 tcgttgacca aggttttcag ttaactagcc ttaaaagtga gctccagttg cgtatctttg
    20941 ttaccttttt ctttttaagt tactacggaa gacgcacgtt gccatttcca atcgaaaaaa
    21001 agaagatcaa agaaattatg gtcaagaata attgtcagat gaatttgttt caggaagaaa
    21061 gcccatatga gcaatctttc tttattatgt attttgttgt gcatctcatg agagaatccc
    21121 aaggaactcc atttgaatgg aaagctggag actcttatgt acagttgata aatatcgata
    21181 aaaaagactt cttaatcttg aaaaatctct taggaaaatt gaagtacagc agctatataa
    21241 aagtagtgaa ctattttgtc aatacgattt tttcagaatt ttcggagaaa gaaaaaaatg
    21301 aaatcagtga gcagatacga aaaaatatgt cctactgttc gttttcatcc gctgattgca
    21361 aagaaaaaaa cgaagaatat gttgttcaat tattaacgca aatttatttt ttctcccgta
    21421 ttttcccata cgatacgact catttgacga tccgtgcaac ttactttgca cagcagatgc
    21481 aacaccgcca gatacgtcta tatgctggat ttcgtgcaga acttcaattt tattccactc
    21541 tactgaatca gaatctgatt tattatttat ctagctatat cttttggatg cttatcggta
    21601 atcctgaaat tcaccattat acttctgata aaaaaatact gattatcagc gacttaagtc
    21661 ttcgacatag tcaatatatt gaagaatata tcagtgatat tcttgctgtg cataaaattc
    21721 actctgagac aactgctatt actgaagatc agctgtcgaa atacaatctt ctcgagtatg
    21781 atctgatcgt tacgaatcaa cccattttga atgcccatgt tcctcatata ttgattgatg
    21841 atagtgtgtc attcgcaaat gaagaagaac tcatccgctt attcgagtta tgaataatca
    21901 aaaaacagct atgtataaac caccctgata aaaatttcag gacaaataca catagctgtt
    21961 tctttttatt gtattccttc agcaatccaa cgagatttat agcgaaagtc ttttaacaac
    22021 tcttcttttg tccaattatt tgcaatgaga tccgtcaaag tgttcattac gagggtcatg
    22081 gaaaagtata ggaaactaac tgcttcttcc gacgattgaa tggagaaatg attgattctt
    22141 aataattcca gccatttttc gttcattgga gaatcagccg atagttctct acgtttggtt
    22201 gtctgctgat catttcgctg ggttaacaag tataaccttt gccaatagat actttcgtga
    22261 tctaagtcgc agcaccactc taaatatttt tcgatcccca aaaagaaatg ttgtttgttt
    22321 tcgctaatga attttaagat atcttgatgg actatgtgag aactgctttt gatcgtatac
    22381 aaataagcat cttccaaatc ttgaaaatat ttataaaaag caccgcgcga catccccatc
    22441 ttgtcaacga tttctgagac tttgacttgg ctgatgtgct gtgagcaaaa tatctccagt
    22501 aataggtcat cgattctctg tttctttgcg ttcgataaat tgaaaaaagt ttcttttggc
    22561 atccacatct ctcctttatc tctgattata cgtggatagc ccttcattgt catgaaggat
    22621 tcattccttc tttttctctt cttctgtcaa gtacccatct tccattcgat aaacgcgatc
    22681 actccattga atcatacgga catcatgagt aaccataata gtcgcttttt gtttctcatg
    22741 agcttcttta actagtaatt tgacgacttc atatgcatga tctgtatcca aactagctgt
    22801 tggttcgtct gctaagatca agcttggctc attatataaa gcgcgagcaa ttgccactct
    22861 ctgtctttct ccaccagaaa ggtctttagg ataactattt ttaagtgact ggatatctaa
    22921 agattgcagc aaggaatcga tttttgttga atcttctttt tttgaagtaa cttggtcaac
    22981 tagttcaaat tgttccttta ccgttaaaaa aggaatcaaa ttagagcttt ggagaataaa
    23041 tcctatttct ttaaagcgta aatctgctcg ttttttttct ggaagctcag ttagtgagtg
    23101 accgttgatc actatttctc cggaagtcgg tgtttgcaat cctcctgaaa tggtaaggaa
    23161 agtactttta cctgaaccag aaggaccaat gatgctgacg aattctcctt cctttacata
    23221 aaaatcaatt gctttcaaag ctgagacctt tgtatgacca gaaccaaatg ttttggtaac
    23281 ttttttcatc gttaatattt ttttcatttt tattaacctc ctattgctgt aattgggtct
    23341 actttggtta tcgtacgtat cgaaaacaat ccgcctagca ttgcgacaat gatcaaaatc
    23401 ccactatata gcaaccattg tgaccaaaaa acagcaaaag gcatcgcgct tggtaaaatc
    23461 agactagtca aataagcaaa caaaagagca agcagaacgc ctaccacccc aacaataaag
    23521 gactgtgcta ctaaagattt agcgatgaag aaatttttga tcccttgtgc tttcattact
    23581 ccaaaaatag cagtcttctg aagtgtcatc acgtacatga aaataccgac cacggcagca
    23641 accactaaga acaaaaagta tatcatcgca tttaaggtca tattttgggc agaatagcca
    23701 ggaatacttt caatgaatgt cccaatagtt aataactgta gacccttcga tgctttttct
    23761 ttcgaaattt tagctgaatc ctttattacg atcccattga tcggctgttc ttcttcagaa
    23821 gcaaacggct gttgtccata cttcaaagca gtccacgtat ctagggacgc atagatgacg
    23881 ggagaaactg tgtaataagt ttcaggaaag ataccgacaa tcgtcaaagg atcgtcgtaa
    23941 ctgccaattt tgatcgtatc tccaatttta tagcctgaat cagccagatt ttgagagatg
    24001 atgatttcat tctttgtttt aaattcatgc cctttcgtga gttttggtaa taaaaatgct
    24061 tctttcgttg tgccgaaaac tgtaacattt tctttgtttt ttcctttgat tgctccgctg
    24121 tacaatccga ttggtgcttt ctctcctcct tcaatgtatt tcagatctcc tcttgttaat
    24181 tgtgaagctg caaatacttg atttgcatcc tccgacaaaa caatctcttg tgcgtcccaa
    24241 tcatcgattg cttttttaaa ctcttctgaa agtccattcg ctagtcctga caacatgaat
    24301 acgacatacg caatcaagaa cataataccg acgatcaagc catatcgtaa tttagaatag
    24361 cgaatttctt tgatagctag aaacatttgt ttttcctccc tatgatagat tgatagtgac
    24421 aaaatgtcac ttgttgaata gtgtaactct aaagtgacaa tttgtcactt gtgttgtttt
    24481 tttcttatca ataaattgtc taagacatct ttcgataaaa ccttaacatg agtcataaaa
    24541 aatttattta agccttattt atgctttcca tgataaacta aagtgaccaa atcaatgagg
    24601 tgggaaaatg attaaactat tagtagtaga agacgataaa gtattatcca ataatataaa
    24661 agaaatactc gctgcaatcg gcgagataac acaagtttat gatggtagtg aaggactgtt
    24721 cgagttggaa agtggagttt atgatcttgc aatcttggat ttgatgatgc cggaaatgaa
    24781 tggatatgaa gtgttagcaa aaatacggaa agaaaaaata cagactccag tattgatttt
    24841 gactgcaaaa gatagtttgg aagataagat tgaaggattt gaacgaggtg cagatgatta
    24901 tctaacaaaa cctttctatc gagaagaact gatcatgcgc gtgaaagcat tattgaaacg
    24961 ctcgctaggt ctctttgatg aaaatgttct gaagtataag gatatcagtt gtgatttaaa
    25021 aagcaatgaa gtcttgtata aagaacaagt tttgcccata caaggaaaag agtttgaatt
    25081 gctcgtttat tttttacaaa ataagggaat cattttgaca aaagagcaga tatttgaccg
    25141 gatctgggga tttgattctg atacgacgat tacagttatt gaagtttata tgagcaactt
    25201 acgaaaacat ctgcgaagta ctggattgga taaagaaatc aaaaccttac gtaatgtcgg
    25261 ttatatactg caaagggtgt gatgcaatga atggagatat tacacgaaag caacgtagtc
    25321 gcttttttgc gacaaatgta gcagcatttg cttttatctt ttttcttttg ggattcatta
    25381 ctttacagat attaaaccaa tctgcataca gagaaacaga tctgtcatta gagaaaataa
    25441 attttgattc tcgaacagta caattagaga tacaaagata tcagcaaggc gatccctttt
    25501 taaacccgac tcaaacggaa caaaacagaa caaacatgga acagccatta atggaaccat
    25561 caaatgaccg ttttaacact caagtgatct tgtggtctaa aaatggtgag atattgaata
    25621 aagcagctat tggtgggcgt ttcaaccaaa tcaaagaatt aaaaatggat acgaaaaatc
    25681 tgaataccat ccaaaatatt gaattaaatg aagacagtgg ctcatctgcc ctctctttcc
    25741 gttcgattac gaaaaaagcg gagacgaatc aagatggcgt tgcctacatc caaattttag
    25801 aaaatacaaa tcaaatcaag aattcattag cgacttttcg cacgattatg attttgtgta
    25861 tgattgtttt ttggattctc tctattggta tcagttatta cttgtctagt ctaagcatgc
    25921 gccctattat tctttcttgg agaagacaaa aagaatttgt tgagaatgct tctcatgaat
    25981 tgcgcacacc gttaacgatt attcaaaata gtttggaaca tctttttacc aagcctaatc
    26041 atactattat tgaagaatcc gaaagcatcg ctcaagcatt gtcagagacg aggcgcctca
    26101 ctggattgac ttcggatttg ctgacaatcg ctcggaatga ttctgatcag cagctgcttt
    26161 caaagcaaat gatcaataca caagaatata tcgaacaact tgttaaacca tttcaagaga
    26221 tggccatcat agatggaaaa gagtttattc tccataacga tgcaacatta gaagtaccaa
    26281 ttgatgaaaa aaaaatccat caagttttgg ttattttgct ggataatgca ttaaaatata
    26341 cgaatccaga agataagatc attttggatt catctgttaa ccataaagaa tggctgattc
    26401 acgtaaagaa tactggccct tctatcagtg aagaagatca agcaaggatt tttgatcgat
    26461 tttatcggga agatcaatct cgggcgaaag agactggcgg atacgggctt ggcttggcaa
    26521 ttgcaaaaca ggtaatcgaa cagcatcatg gacagatttc tgtatccaat tatcttccac
    26581 aaggagtcga ttttaaagtc caattgccgt tgaagcctaa aaaataatgc ttatccctaa
    26641 aaaagggctg tgacaaaaat cttgtcacag cccttttttg ttgcgaataa acggtgttcc
    26701 agaagtagct tcttcggaaa taagccgaaa tttctttaag ctgaccactt ctgtcacaac
    26761 ctctttagct tacgcttacg attttttatt gcggtcttca atgtgtacat caccgcttgt
    26821 gtcaatatcc aattcttctc ggctaacatc ttctgtcact ttttcaacat cttcatgttc
    26881 ttctttatga atcccaactt cttcacgaat aactgtatgt ttgcttacat ctacttgctc
    26941 ttctttgatt gggatagtaa tcgtgtcatc ttccaatttt tcgtctgttc cctgtgaaga
    27001 ttgatctgtt actggtttgc gttcgatgac gatttcttca cgtttgaccg gtacttctac
    27061 cgtttcagta tcgttgacca catgtttgtg gatgtcgact tctccagttg tcacatcatg
    27121 tgtatttaca tctaattttt cttcttttag ttgaattgta tcatcatcta gatttggttt
    27181 gcgatcgatg tcttcagtct tgcttgtacc cattgtatca gtctcgccag gtacgtccat
    27241 cggatcagtt cctggtgtca tattcaatgg atccgttgta ttttgaaagc ctgtcgtgcc
    27301 acctacgtcc attggatctg ttccagtgcc agtttctaat ccagtcccca ttgtgcttgc
    27361 tgggctaaca gtatcttgtg tatccattgt atcttctgtt gtttctggct gacgatagcc
    27421 ttttactgtg atgacaaatt ttccatcaga aatatctcct ctatattgat ataaaggatc
    27481 attttctggt gtagccgtct cagaatcata ggtatcaaaa gaaaaagtat cttttatttt
    27541 ttcccataaa gaacggtctt cttcaccatc catccgattt tcatctgttt caacatctat
    27601 accagacaat ccgtcaaatc ctagtctaga tgctgcttca tcagtagtat aaataacgat
    27661 atcatctcgt tcataccctt cgttacgcaa ccgttcaatt actgataatg cttcttccct
    27721 cgtactatag cttccgatga ccgttaaatt tttctcttcc atgtaaattc ctcctagcaa
    27781 atagatttat gattggtata ttgttact
//
LOCUS       DAZAOD010000025        27666 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000025 DAZAOD010000000
VERSION     DAZAOD010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.026"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(79..765)
                     /gene="gpmA"
                     /locus_tag="ACHDPO_001139"
     CDS             complement(79..765)
                     /gene="gpmA"
                     /locus_tag="ACHDPO_001139"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFN3368781.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(937..1518)
                     /locus_tag="ACHDPO_001140"
     CDS             complement(937..1518)
                     /locus_tag="ACHDPO_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3368782.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="ACHDPO_001141"
     CDS             complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="ACHDPO_001141"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFN3368783.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            2653..3066
                     /gene="rpsL"
                     /locus_tag="ACHDPO_001142"
     CDS             2653..3066
                     /gene="rpsL"
                     /locus_tag="ACHDPO_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFN3368784.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            3150..3620
                     /gene="rpsG"
                     /locus_tag="ACHDPO_001143"
     CDS             3150..3620
                     /gene="rpsG"
                     /locus_tag="ACHDPO_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFN3368785.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            3714..5801
                     /gene="fusA"
                     /locus_tag="ACHDPO_001144"
     CDS             3714..5801
                     /gene="fusA"
                     /locus_tag="ACHDPO_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFN3368786.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            5973..7160
                     /gene="tuf"
                     /locus_tag="ACHDPO_001145"
     CDS             5973..7160
                     /gene="tuf"
                     /locus_tag="ACHDPO_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFN3368787.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            7567..7875
                     /gene="rpsJ"
                     /locus_tag="ACHDPO_001146"
     CDS             7567..7875
                     /gene="rpsJ"
                     /locus_tag="ACHDPO_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFN3368788.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            7906..8535
                     /gene="rplC"
                     /locus_tag="ACHDPO_001147"
     CDS             7906..8535
                     /gene="rplC"
                     /locus_tag="ACHDPO_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFN3368789.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            8563..9186
                     /gene="rplD"
                     /locus_tag="ACHDPO_001148"
     CDS             8563..9186
                     /gene="rplD"
                     /locus_tag="ACHDPO_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFN3368790.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            9186..9476
                     /gene="rplW"
                     /locus_tag="ACHDPO_001149"
     CDS             9186..9476
                     /gene="rplW"
                     /locus_tag="ACHDPO_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFN3368791.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            9515..10348
                     /gene="rplB"
                     /locus_tag="ACHDPO_001150"
     CDS             9515..10348
                     /gene="rplB"
                     /locus_tag="ACHDPO_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFN3368792.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            10391..10669
                     /gene="rpsS"
                     /locus_tag="ACHDPO_001151"
     CDS             10391..10669
                     /gene="rpsS"
                     /locus_tag="ACHDPO_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFN3368793.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            10692..11039
                     /gene="rplV"
                     /locus_tag="ACHDPO_001152"
     CDS             10692..11039
                     /gene="rplV"
                     /locus_tag="ACHDPO_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFN3368794.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            11053..11709
                     /gene="rpsC"
                     /locus_tag="ACHDPO_001153"
     CDS             11053..11709
                     /gene="rpsC"
                     /locus_tag="ACHDPO_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFN3368795.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            11712..12146
                     /gene="rplP"
                     /locus_tag="ACHDPO_001154"
     CDS             11712..12146
                     /gene="rplP"
                     /locus_tag="ACHDPO_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFN3368796.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            12136..12324
                     /gene="rpmC"
                     /locus_tag="ACHDPO_001155"
     CDS             12136..12324
                     /gene="rpmC"
                     /locus_tag="ACHDPO_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFN3368797.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            12349..12615
                     /gene="rpsQ"
                     /locus_tag="ACHDPO_001156"
     CDS             12349..12615
                     /gene="rpsQ"
                     /locus_tag="ACHDPO_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFN3368798.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            12673..13041
                     /gene="rplN"
                     /locus_tag="ACHDPO_001157"
     CDS             12673..13041
                     /gene="rplN"
                     /locus_tag="ACHDPO_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFN3368799.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            13078..13386
                     /gene="rplX"
                     /locus_tag="ACHDPO_001158"
     CDS             13078..13386
                     /gene="rplX"
                     /locus_tag="ACHDPO_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFN3368800.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            13414..13953
                     /gene="rplE"
                     /locus_tag="ACHDPO_001159"
     CDS             13414..13953
                     /gene="rplE"
                     /locus_tag="ACHDPO_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFN3368801.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            13972..14157
                     /locus_tag="ACHDPO_001160"
     CDS             13972..14157
                     /locus_tag="ACHDPO_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFN3368802.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            14193..14591
                     /gene="rpsH"
                     /locus_tag="ACHDPO_001161"
     CDS             14193..14591
                     /gene="rpsH"
                     /locus_tag="ACHDPO_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFN3368803.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            14623..15159
                     /gene="rplF"
                     /locus_tag="ACHDPO_001162"
     CDS             14623..15159
                     /gene="rplF"
                     /locus_tag="ACHDPO_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFN3368804.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            15320..15676
                     /gene="rplR"
                     /locus_tag="ACHDPO_001163"
     CDS             15320..15676
                     /gene="rplR"
                     /locus_tag="ACHDPO_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFN3368805.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            15697..16197
                     /gene="rpsE"
                     /locus_tag="ACHDPO_001164"
     CDS             15697..16197
                     /gene="rpsE"
                     /locus_tag="ACHDPO_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFN3368806.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            16212..16391
                     /gene="rpmD"
                     /locus_tag="ACHDPO_001165"
     CDS             16212..16391
                     /gene="rpmD"
                     /locus_tag="ACHDPO_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFN3368807.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            16435..16875
                     /gene="rplO"
                     /locus_tag="ACHDPO_001166"
     CDS             16435..16875
                     /gene="rplO"
                     /locus_tag="ACHDPO_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFN3368808.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            16875..18170
                     /gene="secY"
                     /locus_tag="ACHDPO_001167"
     CDS             16875..18170
                     /gene="secY"
                     /locus_tag="ACHDPO_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFN3368809.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            18232..18879
                     /locus_tag="ACHDPO_001168"
     CDS             18232..18879
                     /locus_tag="ACHDPO_001168"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFN3368810.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            19070..19288
                     /gene="infA"
                     /locus_tag="ACHDPO_001169"
     CDS             19070..19288
                     /gene="infA"
                     /locus_tag="ACHDPO_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFN3368811.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            19321..19437
                     /gene="rpmJ"
                     /locus_tag="ACHDPO_001170"
     CDS             19321..19437
                     /gene="rpmJ"
                     /locus_tag="ACHDPO_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFN3368812.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            19455..19820
                     /gene="rpsM"
                     /locus_tag="ACHDPO_001171"
     CDS             19455..19820
                     /gene="rpsM"
                     /locus_tag="ACHDPO_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFN3368813.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            19848..20237
                     /gene="rpsK"
                     /locus_tag="ACHDPO_001172"
     CDS             19848..20237
                     /gene="rpsK"
                     /locus_tag="ACHDPO_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFN3368814.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            20317..21255
                     /locus_tag="ACHDPO_001173"
     CDS             20317..21255
                     /locus_tag="ACHDPO_001173"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFN3368815.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            21283..21663
                     /gene="rplQ"
                     /locus_tag="ACHDPO_001174"
     CDS             21283..21663
                     /gene="rplQ"
                     /locus_tag="ACHDPO_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFN3368816.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            21935..22774
                     /locus_tag="ACHDPO_001175"
     CDS             21935..22774
                     /locus_tag="ACHDPO_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFN3368817.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            22750..23619
                     /locus_tag="ACHDPO_001176"
     CDS             22750..23619
                     /locus_tag="ACHDPO_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFN3368818.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            23609..24406
                     /locus_tag="ACHDPO_001177"
     CDS             23609..24406
                     /locus_tag="ACHDPO_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFN3368819.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            24609..25355
                     /gene="truA"
                     /locus_tag="ACHDPO_001178"
     CDS             24609..25355
                     /gene="truA"
                     /locus_tag="ACHDPO_001178"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFN3368820.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            26019..26213
                     /locus_tag="ACHDPO_001179"
                     /pseudo
     CDS             26019..26213
                     /locus_tag="ACHDPO_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(26401..27177)
                     /locus_tag="ACHDPO_001180"
     CDS             complement(26401..27177)
                     /locus_tag="ACHDPO_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFN3368821.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            27300..>27666
                     /locus_tag="ACHDPO_001181"
     CDS             27300..>27666
                     /locus_tag="ACHDPO_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HFN3368822.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQL"
BASE COUNT         8996 a         5062 c         5843 g         7765 t
ORIGIN      
        1 agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg tgtcacagtc
       61 ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt catcatttaa
      121 ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt cgtcagagat
      181 accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta ctaaaacagt
      241 tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag cgcgttctaa
      301 tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg cgtaacgacg
      361 gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag tatcgtaaga
      421 acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt ttttgttcaa
      481 accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt gtggtaccca
      541 aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag ttaaaacaga
      601 agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc cttcttttgc
      661 ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt ggttcaatgc
      721 attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta gctctccttt
      781 taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat tttttggaag
      841 agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga atataaaaaa
      901 acgaacagtg cccacgcaac tgttcgtttt taggtattag atgcataatt gctcgatttc
      961 tttttcaggt aaattgatat atttataaca tgttccaact gaaacaccgc attttgaaga
     1021 aataaattgg atcgtttctt ttttttcata atagagacgt cggatttttt tgatcgtttt
     1081 tgcatcgatt tttggtcttc cgccgatttt tcctttttta cgagcttcat ctaatccaac
     1141 taatgtacgt tctttgatca atgcgcactc catgtttgct aggttttcca ttaattggaa
     1201 atagattttt cccatttcgc gcgtatcgat tccttcatca agactaatca agtgcagccc
     1261 gcgatctttg aataattgcg tgagttctgt taattgccgc gtagatttgc ctaatcgatg
     1321 aagttggcaa atgactagtg catcgccttg ttgcatgtca gcgatcactg actccaaatg
     1381 aacagcagta gaatcatttt gttccacttc atatgtctca tggaaaattt cttgacaacc
     1441 aaagtcagat aattgatcaa cctgagttgt taaatcaacg tcatttatgg ttgtgcgtgc
     1501 ataaccaata attttcatgg tgattccttt ctagcagtga ttttctaact ggatataaca
     1561 gtaaaaatgt agcataaagt acgtcaaaaa gatagttttt tcgcaaattt tccgctgtct
     1621 ttttttattg gatgatcaag cagtttttct ttatttacga cggattgcgt caagaatctc
     1681 aacgcctttt tctgagccga caactacttt agaaaccatg tttaggaaaa gcccatgttc
     1741 tactacccca acaagttcat ctaaataggt agctaagctt tctggctgtt cgatgacttc
     1801 tagatgcaga tcaatgatgt aatgaccacc atctgtggtt aagacttctc cgttttcgtc
     1861 tgtacgcaag acgggttgga atcttttttc ttcaaaaata tgaagtagct gttgggagcc
     1921 ataagggatc acttcaactg ggagtgggaa cttcccaagt ttatcgacta atttagaaga
     1981 atcaacgatc caaatcgttt cttttgagta cgtagcgact attttctcga aaagcaaagc
     2041 agcgccgccg cctttgatcc cttgaaaatc agcactgatt tcatcagcac cgtctattgt
     2101 caaatcgact acggggactt catcaatact ctttaacggt attcctaatt tttccgcttg
     2161 ttcttttgtc gcatttgaag tagtaactcc tgtgatacgt aaaccttctt cacgcatacg
     2221 gcgaccaatc tcttctacca tataataggc ggttgaaccg gtcccgagac ctacgatcat
     2281 cccgtccttt acgaatttcg cggcttcaat gccagctaat tgttttaaat tcatctttgc
     2341 gtccaccttt ttttagtttg agcatcgtgc tttcctcact attttagcgt gatttacggt
     2401 aaaaagatac cattcttttt tattccaata aagctttttc aaaaaaaatt gcatctcttg
     2461 ttgacatgtt ttttcattcg tgatattcta acaaaggtgc tttatctaca ggtttctgtg
     2521 aagaaacgtg ctgactgttt atcaaagcat atttgataag gatgcagaca ttgcatttat
     2581 tttttatcac aaaaaaagaa ccacctggat gtgtggaact agacgcaaat cgtgggaagg
     2641 aggaaacaag gaatgcctac aattaaccaa ttagtacgta aacctcgtaa atcaaaggtg
     2701 gaaaaatcta attcacctgc tttgaacaaa ggatataaca gctttaagaa aactcaaact
     2761 aacgtaaact cacctcaaaa acgtggggta gcaactcgtg tgggtacaat gacacctaaa
     2821 aaaccgaact cagctttacg taaatatgca cgtgttcgtt tgtcaaactt aattgaagtt
     2881 actgcttata tcccagggat tggtcataac ttacaagaac acagtgttgt attattacgc
     2941 ggtggtcgtg taaaagactt accaggggta cgttaccata tcgttcgcgg tgctttagat
     3001 actgctggtg ttaacgaccg taaacaaagc cgttctaaat acggaactaa aaaacctaaa
     3061 gcttaatttt aattattaaa caaatgaaac ttgcttctac tatatagaag taattactat
     3121 gaacaatatt tcggaaggag gagttacgga tgccacgtaa aggtcctgtt gcaaaacgtg
     3181 atgttttacc agatcctatt tataactcaa aattagtaac tcgcttgatc aaccgtgtaa
     3241 tggttgacgg aaaacgcggt attgcagcta acattatcta taatgccttt gacttgatca
     3301 aagaatctac aggtaacgat ccattagaag tgtttgaaca agcaatgaaa aacgttcaac
     3361 ctgttcttga agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta ccagttgaag
     3421 ttcgccctga acgccgcgtt actctaggtc ttcgttgggt agtaaactac gctcgcttgc
     3481 gcggtgaaca cacaatggaa gaacgcttag caaaagaaat catggatgct gcaaacaaca
     3541 caggtgcttc tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc aaccgtgcgt
     3601 ttgctcacta tcgctggtaa gattctctct gtttggtcgg cttttataag tcgacctcag
     3661 atagtgtcct tatttttagc aactagatag taaagagagg agaaacaagg agaatgacca
     3721 gagaattttc tttacaaaac actcgtaata tcggtatcat ggcccacatc gatgctggta
     3781 aaacgactgc tactgaacgt atcttgtact atactggtaa aatccataaa attggtgaaa
     3841 ctcatgaagg agcttcacaa atggactgga tggaacaaga acaagaacgt ggtattacga
     3901 tcacttctgc tgctactaca gcacaatgga agggtcaccg aatcaacatc atcgacacac
     3961 caggacacgt agacttcaca gttgaagttg aacgttcatt gcgtgtactt gatggtgctg
     4021 taactgttct tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt tggcgtcaag
     4081 caacaactta tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag atcggtgctg
     4141 acttcttata ttcagtatca actttacatg accgtttgca agcaaacgct cacccaatcc
     4201 aattaccaat tggtgcggaa gacgacttca caggaattat cgaccttgta acaatgaagg
     4261 ctgaaatgta tacaaacgat cttggaacag agatcgaaga aacagaaatt cctgaagaat
     4321 accgcgaatt agctgaagaa tggcgcgaaa aattggttga agctgtagct gaaactgatg
     4381 aagaacttac tttgaaatac ttagaaggtg aagaaatcac tgaagctgag ttaaaagaag
     4441 gtatccgccg cgcaacagtt aacgtagaat tctacccagt actatgtggt tcagcattta
     4501 agaacaaagg ggttcaatta ctattggacg ctgttcttga ttacttgcca tcaccgttag
     4561 atatcccagc tatcaaaggg attgacccta aaactgatga agaagtagaa cgtcctgcag
     4621 acgacagcgc tcctttctca gctttagcat ttaaagttat gactgaccca ttcgtaggtc
     4681 gtttaacttt cttccgtgtg tactctggtg ttttacaatc aggttcatac gtacaaaacg
     4741 caacaaaagg caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc aactctcgtt
     4801 cagaaatctc tgaagtttac gctggagata tcgctgctgc tgttggtttg aaagacacaa
     4861 ctactgggga cacactatgt gatgaaaaga gtctagttat tcttgaatcc atggaattcc
     4921 cagaaccagt tatccaagtc gctattgaac ctaaatcaaa agctgaccaa gataaaatgg
     4981 gtgtggcttt acaaaaacta tctgaagaag atcctacttt ccgtgctgaa acaaacgtgg
     5041 aaacaggcga aacaatcatc gctggtatgg gtgaacttca cttagatatc atcgttgacc
     5101 gtatgcgtcg tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta tcttaccgtg
     5161 aaactttccg tgctggcact caagccgaag gtaagtttgt acgtcagtct ggtggtaaag
     5221 gtcaatacgg tcacgtatgg attgaattta caccaaatga agaaggtgct ggtttcgaat
     5281 ttgaaaatgc gatcgtcggt ggggttgttc ctcgtgaata cattccagct gttgaaactg
     5341 gtttgaaaga tgctatggaa aatggtgtct tagctggcta tccattagta gatatcaaag
     5401 ctaaacttta cgatggttca taccatgatg tcgattcaaa tgaaactgcc ttccgtgttg
     5461 ctgcttctat ggcattacgt gcagcagcta agaaagctaa tccagtaatc cttgaaccaa
     5521 tcatggctgt agaagttgtt atccctgaag attatttagg tgatgttatg ggtcacgtaa
     5581 ctgctcgtcg tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa caagttgttc
     5641 gtgcgatggt tccacttgct gaaatgtttg gttatgctac aactcttcgt tctgctactc
     5701 aaggtcgtgg tacatttaca atgacatttg accactacga agatgtacca aaatcagtac
     5761 aagaagaaat cattaagaaa aacggcggaa aagctgaata atttcttgaa accggatagt
     5821 cctgcaaaga gattatccaa agagactata tttttaatat agtttcgtgt aaaataatta
     5881 tcgatgatat gggcatgtgg tgtaccttgt gtacatcata tacctatcag acaaataaaa
     5941 aatatattgt atttttagga ggacatttta aaatggcaaa agaaaaattt gaccgttcta
     6001 aaccacacgt taacattggt actatcggac acgttgacca tggtaaaact acattaacag
     6061 ctgcaatcac aactgtacta tctaagaaaa acggcggcca agctatggct tacgatcaaa
     6121 tcgatggtgc tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct cacgttgagt
     6181 atgaaacaga tacacgccac tacgctcacg ttgactgccc aggacacgcg gattacgtta
     6241 aaaacatgat cactggtgct gctcaaatgg acggagctat cttggtagtt tctgctgctg
     6301 acggcccaat gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt ggtgttcctt
     6361 acatcgttgt attcttgaac aaagtagaca tggttgatga cgaagaatta ctagaattag
     6421 ttgaaatgga agttcgtgac ctattaacag aatacgaatt ccctggtgac gatgttcctg
     6481 tagttgctgg atcagctttg aaagctctag aaggcgacgc ttcatacgaa gaaaaaattc
     6541 ttgaattaat ggctgcagtt gacgaataca tcccaactcc agaacgtgac aacgacaaac
     6601 cattcatgat gccagttgaa gacgtgttct caattactgg acgtggtact gttgctacag
     6661 gtcgtgttga acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt ggtattgctg
     6721 aagaaacttc aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg ttagactacg
     6781 ctgaagctgg agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa gacatccaac
     6841 gtggacaagt tttagctaaa ccaggtacaa tcacacctca tacaaaattc tctgcagaag
     6901 tatacgtgtt gacaaaagaa gaaggtggac gtcatactcc attcttcact aactaccgtc
     6961 cacaattcta cttccgtaca actgacgtaa caggtgttgt tgaattacca gaaggaactg
     7021 aaatggttat gcctggcgac aacgtaacaa tggaagttga attaatccac ccaatcgcta
     7081 tcgaaaacgg tactaaattc tcaatccgtg aaggcggacg tacagttggt gccggtgtcg
     7141 ttacagaaat caaagcttaa ttcacttaag ttttaaagta aagcaacatt tattcggacg
     7201 taatcgctcg gaacgaaggt cttaggatct ttgttccgag cttttttatt tattgcagga
     7261 tcaggaaaaa agacaggagt attataaata gaagaaacac gaaataaaag agtcagtatt
     7321 ttctaaatga aactttatga aaacaaaatg ttttttacaa gaaaaagcct tgctttgtga
     7381 gtttatatat attataatga caaaggtgcg tttactttag tgaattgcac agacgtaatc
     7441 agaatgattt cgtcggctaa gaaacgagag gttgcgacac gcccggacgc tttgccacga
     7501 acgagcgtga cggaaatttt cgtggagcta tgtctacttt tcaaaatagg cgaaggaggg
     7561 aacaagatgg caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca ccgtatttta
     7621 gatcaatcag cggataaaat cgtggaaact gcaaaaagaa ctggagctag cgtgtctggt
     7681 ccaattccat taccaactga acgcagtctt tacacaatca tccgtgcgac tcataaatac
     7741 aaagattcac gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga cattgtgaac
     7801 ccaacaccaa aaactgttga tgctttgatg aagctagact taccatctgg tgtaaacatc
     7861 gaaatcaaat tataaaacta aaacaaaaat aatggaggtg tactcatgac caaaggaatc
     7921 ttagggaaaa aagtgggaat gacacaaatc ttcactgaat ctggtgaatt aattccagta
     7981 actgttgtag aagctactcc aaacgtagta ctacaagtga aaacaatgga aacggatggc
     8041 tacgaagcta ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa caaacctgcg
     8101 aaaggtcatg ttgcaaaagc aaacacggct cctaagcgct tcattcgtga attcaaaaat
     8161 gttgagctag gagaatatga agtaggaaaa gaaattacag tagatgtttt ccaagcagga
     8221 gacattattg atgtaacagg tactacgaaa ggtaaaggat tccaaggggt tatcaaacgc
     8281 cacggacaaa gccgcggacc aatggctcac ggttctcgtt accatcgtcg tcctgggtca
     8341 atgggtccag ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg ccgtatgggt
     8401 ggcaaccgcg taactatcca aaacttggaa gttgtacgtg tcgatgcaga aagaaatgtt
     8461 atcttgatca aaggtaatgt tcctggagct aaaaaatctt taattactat caaatcagct
     8521 gtgaaagcta aataattgta ggaagaaagg aggaactaag gaatgccgaa tgtagcatta
     8581 ttcaaacaag atggaagcca aaacggtgaa atcacactta acgaagaaat cttcggaatt
     8641 gaacctaatg aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc attaagacaa
     8701 ggaacacacg cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa accatggcgt
     8761 caaaaaggaa caggtcgtgc acgtcaagga tctatccgct caccacaatg gcgtggaggt
     8821 ggcgtagtct ttggaccaac accacgttct tacagctaca aacttcctaa aaaagttcgt
     8881 cgtttagcaa tgaaatctgt attgtcagaa aaagttgctg aaaacaactt ggtagcaatc
     8941 gaaggcttga acttcgacgc accaaaaaca aaagaattca aacaagttct tgctaactta
     9001 tctatcgact ctaaagtatt ggttgttcta gaaaaaggta acgactttgc tgctttatca
     9061 gcacgtaact taccaaacgt ttctgtagta acttctgata atgtgagtgt gctagacgtt
     9121 gtatcaaata caaaagtgtt agcaacacaa actgctctta ctcaaattga ggaggtgctt
     9181 gcataatgaa cttactagac gtaatcaaac gcccagtgat cactgaaaaa tcaatgcttg
     9241 ccatggatga caagaaatac acttttgaag tggacactcg cgcaaacaaa actttagtaa
     9301 aacaagcggt agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc gtgaacgtac
     9361 gtgcgaaatt caaacgtatg ggcaaatatg caggatatac aaaaaaacgt cgcaaagcga
     9421 tcgttacatt gactgaagat tcaaaagaaa tccaattatt cgaagctgct gaataagcac
     9481 taatagataa ctcattaaat taggagggaa aaacgtggcg attaaaaagt acaaacctac
     9541 ctcaaatggt cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa catcaacacc
     9601 tgaaaaatca ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca acggccgcat
     9661 cactgtacgt catcaaggtg gcggacacaa acgccaatat cgcgtgatcg acttcaaacg
     9721 taacaaagat aacgttgttg caactgttca aacgatcgaa tatgatccaa accgttcagc
     9781 taacatcgcg ttagtacact atgaagatgg agtgaaagct tacatcttag cacctaaagg
     9841 actagaagtg ggtatgaaac ttgtttcagg tccagaagca gatatcaaag tcggaaatgc
     9901 tcttccatta gaaaacattc cagttggtac tgttatccac aacattgaaa tgaaacctgg
     9961 taaaggtgga caattgatcc gttctgctgg tacaagtgct caagtacttg gtaaagaagg
    10021 caaatacgta ttgatccgct tgaactctgg tgaagttcgt atgatcttag ctgcatgccg
    10081 tgctacaatc ggttctgtag gtaacgaaca acacgaatta atcaacatcg gtaaagctgg
    10141 acgctctcgt tggatgcgta aacgcccaac tgtacgtggt agcgtaatga accctaatga
    10201 tcacccacac ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac cagtttctcc
    10261 ttggggtcaa ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat cagacaaact
    10321 tattgttcgt cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac attttgagag
    10381 gaggttcacc atgggtcgta gtttaaagaa aggacctttt gtcgatgagc atttaatgaa
    10441 aaaagttgaa gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt ggtcacgccg
    10501 ttcaacagtt ttcccaagtt ttgttggata taccatcgca gtttatgatg gacgtaaaca
    10561 tgtaccagtt tacatccaag aagacatggt aggacacaaa ttaggtgaat ttgcacctac
    10621 aagaacttat cgtggacatg ctgctgacga taagaaaacg aaacgctaat ttgaggggag
    10681 gataaatcca aatggcagaa caaatcacat cagctaaagc aactgcaaaa acagttcgca
    10741 cttcacctcg aaaagcccgt ttagtaattg accttatcag aggtaaaagt gtcgcagatg
    10801 caatttcaat cttgaaattc acaccaaaca aatctgctgg aatcattgaa aaagtattga
    10861 tgtcagcagt tgcgaatgca gaaaataact ttgacttaga tgttgaaaac ttggtagtaa
    10921 gcgaagcttt tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt gcaaaaggat
    10981 cagcttctcc aatcaacaaa cgtacaagtc atatcacggt agtcgtatca gaaaaataag
    11041 gagggataat cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg catcatccgc
    11101 gactgggatg ctaaatggta tgctgaaaaa gagtatgctg agttcttaca cgaagattta
    11161 agaatccgta aatttatttc aactaaactt gctgatgctg ctgtatcaac agttgaaatc
    11221 gaacgcgcaa caggtcgcgt aaacatttca attcacacag ctaaaccagg tatggttatt
    11281 ggtaaaggcg gttctgaagt cgaaagccta agaaaagaat taaacaaatt aactggtaaa
    11341 agaatccata tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa attagtaggt
    11401 gaaggaatcg cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca aaaacaagcc
    11461 atccaacgct caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc tggtcgtcta
    11521 aacggagcag atatcgctcg ttcagaagga tactcagaag gaactgttcc tcttcatact
    11581 ttacgtgcgg acattgatta cgcatgggaa gaagcagata caacatacgg aaaactagga
    11641 gttaaagtgt ggatctatcg tggagaaatt cttccaacta aaaaaaacac tgagaaagga
    11701 gggaaataat catgttagta cctaaacgtg taaaacaccg tcgtgaattc cgcggaaaaa
    11761 tgcgcgggga agctaaaggc ggaaaagaag tagcattcgg tgaatacggt ttgcaagctg
    11821 ttgattcaca ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca atgactcgtt
    11881 acatgaaacg tggtgggaaa gtatggatta aaattttccc tcacaaatct tatactgcca
    11941 aagcaattgg ggtacgtatg ggttctggta aaggggcacc tgaaggatgg gttgcaccag
    12001 taaaacgtgg taaaatcatg tttgaaatcg caggcgttcc tgaagaagta gctcgtgaag
    12061 cgttacgtct agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa cgtgaggaaa
    12121 tgggtggtga atcgaatgaa ggttaaagaa atcagagaat taaccactgc cgaaatgctt
    12181 gatcaagaaa aacaattaaa agaagaattg tttaatctta gattccaatt agcaacaggt
    12241 caattagaaa acactgcacg tattaaagaa gtacgtaaat cgattgcacg catcaaaact
    12301 gtgttgcgtg aacaagctaa gtaattatgg aaggaggcca ttaagcgtat gactgaagga
    12361 agaaatcaac gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga taaaacaatt
    12421 accgttgctg tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat gaactattct
    12481 aagaaataca aagtgcatga tgaaaacaac acagcaaaag ttggcgacat cgtgagaatt
    12541 atggaaactc gtccattatc agctacaaaa cgtttccgtt tgttggaagt agtcgaagaa
    12601 gcagttatta tctaataaca cgagattttc ctatatagat tgaatgcaaa atctgaaagg
    12661 aggatacaca acgtgatcca agcagaaagt cgtttaaaag tcgctgataa ctcaggcgca
    12721 cgtgaaattt tgacgatcaa agtccttggt ggatctggtc gtaaaactgc taacatcggt
    12781 gatgtgatcg ttgctacggt taaacaagca acgccaggtg gggttgtcaa aaaaggtgac
    12841 gtcgttaaag ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga cggttcatat
    12901 attaaatttg atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc tcgtggaaca
    12961 cgtatctttg ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa gatcgtttca
    13021 ctagcaccag aagttttata atcttgagac acttatcaaa ggaggtgcga aacagttatg
    13081 tttgttaaaa aaggcgataa agttaaagtt atcactggaa aagacaaaaa caaagaaggc
    13141 gttgtactag cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt aaatgtcgtt
    13201 aaaaaacacc aaaaaccttc tcaagctgct cctcaaggtg gaattgttga gatggaagcg
    13261 ccaattcatg tttctaacgt gatggtggtt gactctactg gtgtagctgg ccgagttggc
    13321 tacaaagaag tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga agttttagat
    13381 aaataaaagt ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga aaaatatctt
    13441 aaagaagtaa ctccatcatt gatggaaaaa tttaactata gctctgttat gcaaacacct
    13501 aaagttgaaa aaatcgtcat caacatgggt gttggtgatg cggtatcaaa cgctaaaaac
    13561 ttagataaag cagttgaaga attaactttg atcactggtc aaaaaccaat gattacaaaa
    13621 gctaaaaaat caatcgctgg attccgttta cgtgaaggaa tgccaattgg tgcaaaagtt
    13681 acattgcgcg gagaaagaat gtacgaattc ttagacaaat tggtttctgt ttcactacca
    13741 cgtgtacgtg acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg aaactatact
    13801 ttaggtatta aagaacaatt gatcttccca gaagtagatt atgatttagt agataaagta
    13861 cgtggtatgg acatcgttat tgtaacaaca gcaaactctg atgaagaatc tcgtgagttg
    13921 ttgacacaat taggcatgcc attccaaaaa taattaaagg aggcgaacta cgtggctaaa
    13981 aaatcaatga ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc ttatactcgt
    14041 tgcgaacgtt gcggacgtcc acattcagtt tatcgtaagt tccatctttg ccgtatttgc
    14101 ttccgcgaac ttgcctataa aggtcaaatt cccggcgtga agaaagctag ctggtaaaaa
    14161 gtaaattcgc ataagaagga ggtaaaagat caatggtcat gacagatcca attgcagatt
    14221 ttctaactcg tatccgtaac gcaaacatgg ttaaacatga gtctttagaa gtacctgcat
    14281 caaaaattaa acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt cgtgatgttg
    14341 aatacatcga agatgacaaa caaggcgtga tccgtgtttt cctaaaattt ggtaaaaacg
    14401 gcgaacgtgt tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt gcttatgtca
    14461 aagctgacga agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt tcgacttctg
    14521 aaggtgttgt cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa gttatcgctt
    14581 acgtatggta atcaagtaga atctacaagg aggtgtcttt aagtgagccg tatcggaaat
    14641 aaagtcgttg ttatccctga aggagtaaca gttactcaag acggaaacaa cgttacagtt
    14701 aaaggaccaa aaggtgaatt gactcgtact ttttcagcag atatcaaaat gaatatcgaa
    14761 ggaaacgaag taactttcac tcgtccaaac gacagtaaag aaatgaaaac aattcatgga
    14821 acaactcgtg cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt ccaaaaagcg
    14881 ttagaactaa tcggggttgg gtaccgtgca caattacaag gatcaaaact tgtattgaac
    14941 gttggttact cacatccagt agaaatcaca ccaccagctg gagtaactgt tgaagtacca
    15001 gctaacacac aagtaattgt taaaggtgcg aacaaagaag aagttggcga attagctgca
    15061 aacattcgtg gaactcgtcc tccagaacct tataaaggta aaggtattcg ttatgttggc
    15121 gaatatgtac gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa aattgcatag
    15181 aagccagcag caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa tacattttta
    15241 cttgtgccgc agcttctatt tttcgaaacg tatttactgc ttgaaatagt agtacaataa
    15301 aaataaagag gtgacaattg tgattacaaa accagataag aacaaaacac gtcaaaagag
    15361 acatcgtcgt gtacgtaaca atatctctgg tactgctgag cgcccacgct tgaacgtttt
    15421 tcgttctaac aaaaacatct acgctcaaat tattgatgac gtagcgggtg taacgctagc
    15481 aagtgcctct accttggata aagaaatttc aggtggaaca aaaacagaag cagcacaagc
    15541 tgtcggtaaa ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag tagtctttga
    15601 ccgtggtgga tacctttacc atggccgtgt gcaagcttta gctgaagctg ctcgcgaaaa
    15661 tggactagaa ttttagaaga aggaggaata ccattcatgg tttatatcga tccaaaacat
    15721 ttggaattag aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt taaaggtgga
    15781 cgtcgtctac gttttgctgc tttagttgtt gtcggtgaca aaaacggaca cgtagggttt
    15841 ggtacaggta aagctcaaga agttcctgaa gcaatccgta aagcaattga agatgcgaag
    15901 aaaaacttag ttgaagtacc tatggttggt tcaacaatcc cacacgaagt aatcggtgct
    15961 tttagtggtg gtagaatcct aatgaaacct gctgtagaag gttctggggt tgctgctggt
    16021 ggaccagttc gtgccgtatt agaattagct ggggtagcag atatcacttc taaatcttta
    16081 ggctcaaata caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa acaattgaaa
    16141 cgtgcagaag aagttgcaga acttcgcggc aaatcagttg aagaattaat cggataagga
    16201 ggacaacaat aatggctgaa ttaaaagtta ctttaaaacg cagtattatc ggacgtcctc
    16261 aaaaccaacg cgatacagtt aaagcgttag gtcttacaaa gattaacagt tcagtggtta
    16321 agccttctaa tgaagcaatt aaaggcatga tcaatactgt ttctcaccta gtggacgttg
    16381 aagaaattta atttagaaaa atcataacta gaacattaag gaggtgccaa acctatgaaa
    16441 cttcatgaat taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt tggtcgtggt
    16501 acttcatctg gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa agctcgttca
    16561 ggcggcggtg tgcgtttagg atttgaaggg ggacaaacac cattgttccg tcgtttacca
    16621 aaacgaggat tcacaaacgt gaaccgtaaa gactatgcag tcattaatct tgatgtattg
    16681 aaccgctttg aagacggagc tgaagtaact cctgttgctt tagttgaagc tggaatcgtg
    16741 aaaaacgaaa aagctggaat caaagtatta gctaatgggg aactaaacaa gaaattaact
    16801 gtgaaagcag caaaattctc taaagcagct caagaagcaa ttgaagcggc tggtggatca
    16861 atcgaggtga tctaatgttt agactattaa aagatgcttt taaagtaaaa gacattagat
    16921 cgaaaatcct atttactgta tttgtgttgt ttgtatttcg cctaggtgca catattactg
    16981 taccaggcgt aaatgctgct tcattgcaaa acctttcttc tttgccattt ttcaacatgt
    17041 tgaacttggt aagtggtagt gcgatgcaaa acttttccat tttctcaatg ggggtttcac
    17101 catacattac tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg cctcgatttg
    17161 ttgaatggtc gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg actcgatatc
    17221 tgacattagt attggcattt atccaatctg tcggtatcac tgctggattc aatcaatacg
    17281 ctcaattagg tttcgtgaat aatcctaacg tagcaactta cgtaacgatc ggtttgattc
    17341 taacagccgg tacgatgttt gttacttggc taggagaaca gatcacagaa aaaggtatcg
    17401 gaaatggcgt atcaatgatc atttttgcag gtatcatttc tagattgcct gaaagtatca
    17461 gagaaattta tgaagattac tttataaata ttgatccttc agacatatgg aaatctgcta
    17521 tttttgtggc cattttacta gtagcggtct tgttgatcgt gacattcgta acatttttcc
    17581 aacaagctga acgcaagatc ccgatccaat atacgaaacg cgtagctggc gcgcctacaa
    17641 gcagctatct gccgttgaaa gtaaatgcag ctggagttat tccagttatc tttgctagtt
    17701 cgtttattgc tacgccaaat gctgttttac aagcattgag cggtagattc ggttctgaaa
    17761 actggtacaa agtgatgatg gagatcttta actataatac agcacctggt gctacgattt
    17821 atacgattct gatcgttgcc ttcactttct tctacgcctt tgttcaagta aaccctgaga
    17881 aattagcgga aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc cctggtaagg
    17941 ggactgaaga gtatgtctca agattactga tgcgtttaag tacagttggt gcagtcttcc
    18001 ttggtttagt ggcattgctt ccaatcattg ctcaaatggt ttgggatctt ccacaatcaa
    18061 tcggattagg cggtacaagc ttactgatcg ttatcggtgt agctttagaa actgcgaaac
    18121 agttagaagg cttaatgctg aaacgtaaat atgttggatt cattgagtaa gaaagcgtgt
    18181 tgaggtttcc cctcaacaca cgttctcaca catttattag gagggaaaac aatgaacctc
    18241 attttaatgg ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat cattgatgct
    18301 tatggtattc cgcacatctc aacaggagat atgttccgcg cagcgatgca aaacgaaaca
    18361 gctcttggcc tggaagcaaa gtcttatatg gataaaggtg cattagttcc tgatgaagta
    18421 acaaatggaa tcgtgaaaga gcgactagct gaaccagata cagagaaagg cttcttatta
    18481 gatggctttc cacgtacgct agatcaagca aaagctctgg acgcaatgct aaaagatttg
    18541 aataaaaaaa ttgatgctgt catcgatatc catgttggtg aagaaatctt ggtcgaacgt
    18601 ctagccggcc gatttatctg cagcaattgt ggagcaactt accataaaat tttcaaccct
    18661 acaaaagttg aagacacatg tgatcgttgc ggtgggcatg aattctatca aagagaagat
    18721 gataaacctg agacggttaa aaatcgtctg gctatcaaca tcaaaaatag tgaaccaatc
    18781 ttggcttatt ataaagaaca aggtttgcta aacactattg atggtgctcg tgaaatcgat
    18841 gctgtatttg cagatgtaca aaaaatcatt gaaaaatagc acgattgccc gtagccgact
    18901 tgcattatgc agttactctt gtcaagttca ataaattatg atagaatatg tcagtccgac
    18961 ttctagagaa tcctctagat gatccatttt gagaattttg aggtgggaac tgcagtttcc
    19021 gccattttat cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg tggcaaaaga
    19081 agatatgatt gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa tgtttaaagt
    19141 tgaactagaa aacggacacc aagttcttgc tactgtttca ggtaaaattc gtatgcatta
    19201 catccgtatc ttacctggtg acaaagtaac ggttgaattg tctccatacg atcttaaccg
    19261 tggccgtatt acttatcgct ttaaataatt gtactccgta aaactacagg aggtattatc
    19321 atgaaagtaa gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat tcgtcgtaaa
    19381 ggacgcgtta tggtgatttg cccagcaaat ccaaaacata aacaacgtca aggataattg
    19441 gaggtgctat aaatatggct cgtattgcag gagtagatat tcctcgtgat aaacgtgtag
    19501 tagtttcact tacttatatc tatggtattg gtaacactac tgctaaaaag atcttagctg
    19561 atgctggtgt atctgaagat gttcgcgttc gtgaattaac gaatgaacaa acagatgcta
    19621 tccgtgcaga agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa gtgaacttga
    19681 acatcaaacg tttgatggaa atcggttctt accgtggaat ccgtcatcgc cgtggattgc
    19741 ctgttcgtgg acaaaacacg aaaaacaatg cacgtactcg taaaggccca gctcgcgcta
    19801 tcgctggcaa gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg gcagcaaaaa
    19861 aagtgaatcg taaacgccgt gtgaagaaga atatagaagc aggtattgca catatccatt
    19921 ctacattcaa taacactatc atcatgatca ctgatactca cggaaatgca ttagcgtggt
    19981 catcagctgg ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt gccgctcaaa
    20041 tggcagcaga aactgctaca aaagcagcaa tggaacacgg attaaagact gttgaagtaa
    20101 cagttaaagg acctggttct ggacgtgaag cagcaattcg ttcattacaa gctacaggtt
    20161 tagaagtgac tgcaattcgt gacgtgactc cagttcctca taatggtgcc cgccctccaa
    20221 aacgccgtcg tgtttaatga gtgccgctca ttttgagttt tatcagtaac gtcattgaac
    20281 aagacacttt tcgttttgaa aggggtaaag ataagaatga ttgagttcga aaaaccaaga
    20341 atcgcaaaaa ttgatgaaga aaaagattat ggcaagttca tcgttgaacc tcttgaaaga
    20401 gggtatggga ctactttagg gaattcccta cgtcgtattt tattatcttc tttgccaggt
    20461 gctgccatca ctaatattca aatcgatggt gtactgcatg aattctctac catcaaaggt
    20521 gttagagaag acgtcactca aatcatcttg aacattaaag gcttagcgct gaaaatgtat
    20581 ggccaagaag aaaaaaccct tgaaatcgat attaccggac ctgctacagt aactgctggc
    20641 gatattatcg ttgatagtga tgtagaaatt cttaacaaag atatgtacat ctgtagtgtc
    20701 tctgaaggag ctacgttcca tgctcgctta acagtgaaac ctggacgtgg ttatgttcaa
    20761 gcagatgaaa ataaaaaaga agatatgcca attggcgttc ttccagtcga ttcaatctac
    20821 acacctgttc gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca ccgtgaagat
    20881 tttgataaat tgacgatgga gatttggaca gatggttcaa ttgaaccgtt ggaagcaatg
    20941 agtttgtctg cgaaaatcat gactgaacat ttggatattt ttgtgaactt aactgatgaa
    21001 gcaaaaaatg ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa aatgttggaa
    21061 atgacgatcg aagagttaga cttgtctgtt cgctcttaca attgtttgaa acgtgcagga
    21121 atcaatactg tacaagaact tacaaataaa tctgagcctg aaatgatcaa agtccgtaac
    21181 ttaggacgta aatcattaga agaagttaaa gcaaaattgc acgacttagg tttaggttta
    21241 cgtaaagaag attaaaacct tttacgaagg agggaaacca acgtgagtta tcgtaaacta
    21301 ggacgcacat ctagccaacg taaagcgatg ttgcgtgatt taacaactga tttattaatc
    21361 aacgaacgta ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac tgcagaaaaa
    21421 atgatcactt taggtaaacg cggagatttg catgcacgtc gtcaagctgc ggctttcgta
    21481 cgtaatgaag ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga atcagcttta
    21541 caaaaactgt tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg atacacacgc
    21601 attttgaaga cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt agaacttgtc
    21661 taaaatcaca ctaataacat cactttatag atgattcttt tagagtgtta tgatgttgga
    21721 agatattttt ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct tggggagtaa
    21781 gcactcatca taaagtgttt ttttatacct tcaattacct gtcatgacag atatgtttga
    21841 aggcataaaa aaacatttta agcgagaaat aattgaaaat tttgtctttt tttgatagtg
    21901 ttagtaggaa ctttaggatg aagaaggagt aatcatggag ccaattattg aattagaaaa
    21961 gataaattat aaataccagc cagatgatct tcgccccgca ttgaaagatg tctcctttac
    22021 aattgataaa ggtgagtgga tcgctattat tggacacaat ggttcaggaa aatcgacact
    22081 tgccaaaacg atcaatggat tgcttctgcc agaatcaggg atcgtgaaag tgggaaatca
    22141 aatattggat gaagaaaata tttggacgat ccgacagatg gttggaatgg tttttcaaaa
    22201 tccagacaat cagtttgttg gttcgacagt agaagatgac gttgcttttg gtcttgaaaa
    22261 tcaagggatt cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg agaaagttag
    22321 aatggctgag tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa aacaacgtgt
    22381 tgccattgcc ggcgtggttg ccttacgacc tgatatcatt attttagatg aagcaaccag
    22441 tatgctagat ccagaaggtc gtgaagaagt gatctctacg atcaagaaga tcaaagaaga
    22501 aagtcaattg accgttatat ctatcactca tgatattgat gaagcagcta atgccaatcg
    22561 gatactagtg atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag aaattttttc
    22621 tgctggtcct gaactgatcg acttaggtct agatctacca tttcctgaaa aactgaagag
    22681 cgcactgaaa gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag aaaggatggt
    22741 ggattggtta tggacatccg ttttgaacaa gtagacttca cttatcagcc gaatacacca
    22801 tttgaacaaa gagccttatt tgacatcaat atgacgatca aagaaaacag ttatactgca
    22861 ttagtagggc ataccggaag cgggaaatca accttacttc agcatttgaa tgcgcttgtt
    22921 aagccaacaa gcggtacagt ccatattgga gaacgagata ttcagccgga tacggataat
    22981 aagaatttaa agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc agaagcacag
    23041 ctattcgaag aaacggtagc aaaagacatt gctttcggtc ctaaaaactt tggtgtcagc
    23101 gaagaagaag cactagtcct agcaaaagaa acattagaac aagttgggct ggatgaaagc
    23161 tatttggaac gttcgccatt tgaactttca ggagggcaaa tgcgtagagt agcaatcgct
    23221 ggtgtgcttg ccatgaggcc ggaagtactt gtattggatg aaccaacggc aggacttgat
    23281 ccccagggta gaaaagaaat gatggagatg ttttggcgtc ttcataagga acagcagatc
    23341 actattgtat tagttacgca tttaatggat gatgtagcca attttgcaga ttatgtctat
    23401 gtgttggaaa agggacgaat cgttaatagc ggggagccgc aagaggtctt tcaaaacatt
    23461 gaatggctaa aagaaaaaca actaggcgta cctactgcca ccgagtttgc agaagaatta
    23521 atggctaaag ggatgaactt tgctaccttg cctttgacag ctgaagaatt agcagacgct
    23581 atcgtccatt atgctggagg aaatgcccat gatgaataaa ttgatatttg gtcgttatat
    23641 gcctggagat tccttgatcc atcgattgga tccccgagct aaattattag ccagttttta
    23701 ttttatcgga atcatttttt tagcaaataa ttgggaaacg taccttttgt tggcattttt
    23761 cacattactt tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc gaggcattcg
    23821 cccattgatc tggctaatcc tcttcactgt agctttgcag gtcttgttta caagtggcgg
    23881 agaaacttat tggagttggg gtgttttcca tatcactgaa tttggtgtga tgaacggcct
    23941 ctttattttc tgtcgattcg tgttgatcat ttttatgtcg actctactca cgcttactac
    24001 accgcctttg gaattatcgg atgcgattga gtacttgctt cgtccattga aagccgtacg
    24061 gttcccagtc cacgaaattt cattgatgct gtcgattgct cttcgttttg tgcctacatt
    24121 gatggacgaa acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg attttggtga
    24181 aggaaaccta gttcagaaaa tgaaagcagt cattcctttg ctgattcctt tatttgtcag
    24241 cagcttcaac cgtgcggaag atcttgcgac tgctatggaa gcaagaggct acaaaggtgg
    24301 ggaaggaaga acgaaatatc gtgtattgca ttggcataat agagacacga tggttatcat
    24361 tgcttttgta ttattaactg tgctactgat ctttttgaga ggataaacgt tcagtgggcc
    24421 gctatctatt cttttcttgc tgatctgttt gcaagaaagg atgcgagcag tgtatgacaa
    24481 gaaatattag ggtctgtggc agactaaggt cacaggcctc tttcttttat ctgaaaagaa
    24541 agaacgaaaa aattttataa aaaaatcatt attccagata accttttagg aacaaaggag
    24601 agaaaaacat ggtacgttac aaagcaatca ttgcatacga cggaacaaat tttaatggat
    24661 tccaaaaaca gccaaatggg cgtactgttc aagaagaagt agaaaaaaca ttacaaaaaa
    24721 tggcaaatgg aaaagaaatc acggtctttg gttcgggaag gacagatgcc ggagtacatg
    24781 cgattgggca agtaatccat tttgattatc cagaggagcg tccgttagaa cgaatgcgtt
    24841 tcgcgctaga tacccagtca ccagaggata ttgctgtaag acaagtagaa attgtttcag
    24901 aagacttcca cgcaagatat ttggtcaaag aaaagacgta tcaatttcga gtggatatag
    24961 ggaaaccacg cagtcctttt cgacgccatt atgcaagtta ttttccttac cctcttgatt
    25021 tggaaaaaat tcagcgggcg cttcctgatt tattagggac tcacgatttc acctcttttt
    25081 gtgcatcagg aagctcgata gaggataaag tacgtacgat ctacgaggct aagatggagg
    25141 taaatgaaac aaaagacgaa ttgttgttta catttagggg aaatggcttc ttgtataaga
    25201 tgatacggat cttagtagga acgcttttga aaattggcaa tggccgattg cctgaagata
    25261 gtatcccaga tattattgcg aaaaaagatc gtaatgcagc aggacctaca gcacatcctg
    25321 aaggacttta tttgtatgaa gtgaaatatg aataagaggt tgtgacagaa gtggtcagct
    25381 tcaagaaata agaaggaatt tacgaaaatt acttctcaaa attttgcaaa atttcggctt
    25441 attttcgaag gagctacttc tggaacaccg tgaatcagag gttgtgaaaa agctgccctg
    25501 catcaagtaa taagaacaac caaacaaaaa tagctcgtca tatttttcgt ttggttgggc
    25561 ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg aaatcagcgt
    25621 tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt gccgtttgtt
    25681 gagctaatac cgaaggtcag ctgattgaac accgtttaag aaagaggtcg tgagcctgtc
    25741 atttaactct gagtcacaag taacaatttc aaaaaacagc ttctcatctt tgatgaatat
    25801 cgtgacttgt ggacgaggcg ttgataagtg aatcatcttt ttgttaccta ttttttctgt
    25861 aaccaaaaaa cgatggaacg ttgttttgat tgcccttaat gaggacagtc ggaacaggtt
    25921 tgtcattttt atatttaaat ggcacaaatt tttctaatta tttgtcattt agcgctgaaa
    25981 atttttgcta tttatctaaa aaagtgataa ctacttaaga tgaagcagaa tatttacgcc
    26041 atacggcata caaccgcgaa aaatataaaa aaaagaaaac gattgaacgc gtttttgcag
    26101 tcgcaaagga aaagcatgga atgcgctaca tcaagtatcg agacttggaa aacaatcagg
    26161 tgtatacgct gattgttttt gctgcaatga atctgaaaaa gttgtccact tggcagttgg
    26221 aacatatgtc ttcatatctt ttattataca aaaatagcaa aagcaccagt ctacactctt
    26281 agtaaagagg aaactgatcc ttttgtctac attcttaaag tacttaaact aagtacttta
    26341 ttttactctt taggattgat acagtagcat ctatcccttt attaataatc ttttattttt
    26401 ttaaataaag atgttgtctc catcttcagg cactaaaact ttttcggaaa ttcctttttc
    26461 tttattgaaa gactttaatt cttctcttga cagtccccaa tggtttacag cttccatatg
    26521 aacggcaata attgtggaat ctggtattgc tttatgcaat tcatataaat cgtctttccc
    26581 cataataaga gattctccaa ctaaaaaatg attatctcca gcatttgcta ctatgatttc
    26641 tggattatac tgatcaatag tttgtttaac agcttcatac caaactgtat ctcctgtaaa
    26701 gtatagtgtc ttctcagtcg aatgtttgaa aacaataccg caaacattac ctacataatt
    26761 caagatttct cctctgccat gtttgccttt tgttttaacc aattgtatag attcaaaaac
    26821 tgtgtcttct cgtagtacct ccacattttt aaaaccatat agtcgaattt cattcgcatc
    26881 attttcatct tgcacaaata attttatttc tttaggtagg acctctttcg ctatatcgtc
    26941 ccaatgatct agatgtaaat gtgttacaat aacagcatca ataccgttga taatatcttc
    27001 gactggcatt ggcaaatcaa ctagaggatt catttgatct tttcttggtg atggaaaagg
    27061 acctttcgaa ataaatggtg gaagtgttcc tttttccgct aacattggat caattaaaaa
    27121 ttttttacct ccatagtcta agatagctgt tgcattacga atgtgatgta tattcataaa
    27181 cgttgtctcc tttttgttga tatgaaatat ttttagtata attcaattcc atacaataaa
    27241 taaaccgaac aaaaaaagtc ttttactatt tttacttaat ttatgaaagg ttgtttacca
    27301 tgttagacca aacagatata aatatcattg aggaactatc aaaaaatagt cgaatcacaa
    27361 tgaaagaact tggagaaaaa gtacatttga ctggacccgc tgtctcggcg agagtgacaa
    27421 aactagagga aagtggagtt attgaaaatt atacagtaaa attaaatatg gaaaagctag
    27481 ggttttcgat tcacgctttt ttaattataa ttacgcaaaa tttaaatcat aaaccctatt
    27541 tatcatttat taaaaatcat gaaaaattct tgattagaaa ttataagatt agtggagggg
    27601 gctgttatct tttggaatgt agatttactt caaaaaaatc aatgaacagc tttttggaac
    27661 agctta
//
LOCUS       DAZAOD010000026        26932 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000026 DAZAOD010000000
VERSION     DAZAOD010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.027"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            99..1103
                     /locus_tag="ACHDPO_001182"
     CDS             99..1103
                     /locus_tag="ACHDPO_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368823.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            1104..2048
                     /locus_tag="ACHDPO_001183"
     CDS             1104..2048
                     /locus_tag="ACHDPO_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368824.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            2048..3010
                     /gene="opp4B"
                     /locus_tag="ACHDPO_001184"
     CDS             2048..3010
                     /gene="opp4B"
                     /locus_tag="ACHDPO_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFN3368825.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            3037..3951
                     /locus_tag="ACHDPO_001185"
     CDS             3037..3951
                     /locus_tag="ACHDPO_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368826.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            3977..5758
                     /locus_tag="ACHDPO_001186"
     CDS             3977..5758
                     /locus_tag="ACHDPO_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFN3368827.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            6106..6792
                     /gene="rnc"
                     /locus_tag="ACHDPO_001187"
     CDS             6106..6792
                     /gene="rnc"
                     /locus_tag="ACHDPO_001187"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFN3368828.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            6812..10393
                     /gene="smc"
                     /locus_tag="ACHDPO_001188"
     CDS             6812..10393
                     /gene="smc"
                     /locus_tag="ACHDPO_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFN3368829.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            10402..11211
                     /locus_tag="ACHDPO_001189"
     CDS             10402..11211
                     /locus_tag="ACHDPO_001189"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFN3368830.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            11222..12220
                     /gene="ftsY"
                     /locus_tag="ACHDPO_001190"
     CDS             11222..12220
                     /gene="ftsY"
                     /locus_tag="ACHDPO_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFN3368831.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            12407..14674
                     /gene="gshAB"
                     /locus_tag="ACHDPO_001191"
     CDS             12407..14674
                     /gene="gshAB"
                     /locus_tag="ACHDPO_001191"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFN3368832.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(14763..15215)
                     /locus_tag="ACHDPO_001192"
     CDS             complement(14763..15215)
                     /locus_tag="ACHDPO_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFN3368833.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            15365..16315
                     /locus_tag="ACHDPO_001193"
     CDS             15365..16315
                     /locus_tag="ACHDPO_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFN3368834.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            16308..17267
                     /locus_tag="ACHDPO_001194"
     CDS             16308..17267
                     /locus_tag="ACHDPO_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFN3368835.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            17264..18019
                     /locus_tag="ACHDPO_001195"
     CDS             17264..18019
                     /locus_tag="ACHDPO_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368836.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            18042..18995
                     /locus_tag="ACHDPO_001196"
     CDS             18042..18995
                     /locus_tag="ACHDPO_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFN3368837.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(19639..19935)
                     /locus_tag="ACHDPO_001197"
     CDS             complement(19639..19935)
                     /locus_tag="ACHDPO_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFN3368838.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            20290..20646
                     /locus_tag="ACHDPO_001198"
     CDS             20290..20646
                     /locus_tag="ACHDPO_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFN3368839.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            20656..21555
                     /locus_tag="ACHDPO_001199"
     CDS             20656..21555
                     /locus_tag="ACHDPO_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFN3368840.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            22075..22803
                     /locus_tag="ACHDPO_001200"
     CDS             22075..22803
                     /locus_tag="ACHDPO_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFN3368841.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            22948..24975
                     /locus_tag="ACHDPO_001201"
     CDS             22948..24975
                     /locus_tag="ACHDPO_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFN3368842.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            25083..26180
                     /locus_tag="ACHDPO_001202"
     CDS             25083..26180
                     /locus_tag="ACHDPO_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFN3368843.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            26487..>26932
                     /locus_tag="ACHDPO_001203"
     CDS             26487..>26932
                     /locus_tag="ACHDPO_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3368844.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT         9030 a         4663 c         5687 g         7552 t
ORIGIN      
        1 aagataagaa taacctttgt tataaaacgc tttattctgt gtaatgtcct tttttattaa
       61 gaaaaacttc catttaggaa gcagagaggg gtattcgatt gtccgataac caattattag
      121 aagttcagaa cctacataca ggattccgac tcaaagatga ctattacgat gcagtagatg
      181 acgtttcatt tactttagac aaaaacgaga ttttagcaat cgttggggaa tctgggtgcg
      241 ggaaaagtac cttggctact acgattatgg gattacttga tcctaataac acaaaaatta
      301 caggtgagat tttatataac gatctgaatt taatcgacct gaacgaaacg ctctataata
      361 aaatccgcgg aaatgatatc ggaatgattt tccaagatcc gttgtctgca ttaaatcctc
      421 tcatgagaat cgaagaccag atcaaagaag gactttccta tcacacaaag atgaatgcag
      481 aacagcgtca agctcgtgca ctagaattgc tagaacaagt agggattcct aatcctgcga
      541 gagttggacg ccaatatccc catgaactat caggcggtat gagacaacgt gtcatcatcg
      601 caatcgcaat cgcctgcaaa cctccaatcg tcattgcaga tgaaccgacg acagccctag
      661 atgtaaccat ccaagcacag attcttgatt tactgaaaga ccttcaggaa gaaacaaaaa
      721 cagggatcat cttgatcact catgacttag gagtcgtagc agaaatggct gatcgagtgg
      781 cagtgatgta tggcggacag ttcgttgaag tagcaggtgt aaaagaactg tttgatcatc
      841 ctaagcatcc ttatacacgc tctttactga actctatacc acaagaagga aatcatgatg
      901 cagaactcca tgtgatcgaa ggtgtcgttc cttctctgaa aaacatgcct cgtaaaggtt
      961 gtcggtttgc accacgtatt ccatggatac cagcaagcga tcatgaagaa gagcctatcc
     1021 ttcatgaagt cgcaccgaac cacttggtac gttgctcctg ctataagcat ttccacttta
     1081 gagacgaaaa aggagaggtg tagatgacag aattaatcac aatcaaagac ctgaaagttc
     1141 attaccctat tcgcagtgga ttcttcaatc gagtaacgga tcatgtatat gctgtagatg
     1201 gtgtggattt tattatcgaa aaaggaaaga catatggttt agtgggagag tctggctctg
     1261 gaaaatctac tacgggaaaa gccgttgtgg gattagaaaa ggtaacagcc ggacaaatca
     1321 tgtatgaagg aaaagatgta acgaagcgaa gcaaccgcaa aaaaatgggt tataacaagg
     1381 atgtgcagat gatcttccaa gattcaatgt ccagtttgaa tcctaaaaag cgagtgttgg
     1441 atatcattgc tgaacccatc cgaaattttg aacggttaag cgatcaagaa gaaaagaaaa
     1501 aggtaaaagg actgctagat atcgttggga tgccggaaga tgcgctatat aaatatcctc
     1561 atgaattttc aggcggacaa cgtcaacgtc taggagtagc ccgtgctgtt gctaccaatc
     1621 caaaactgat cgtagccgat gaacctgtat ctgctctgga tctatctgtt caagcgcaag
     1681 tattgaattt catgaaacga atccagcaag aatacggcct cagctattta ttcatttcac
     1741 atgatttagg tgtagtaaaa cacatgtgcg acaatatcgc aattatgtac aaaggtcgat
     1801 ttgtagaaat cggtacaaga gaagacattt ataatgaccc gcgacatatc tatacgaaac
     1861 gtctgctttc agctattccg caaatcgatg tagaaaatag ggaaagccac aaagaaaatc
     1921 gacgaagagt agaacaagag tatatccaaa accaaaaaga atactatgat gcgactggtc
     1981 gagtctacga tttgcgtacg atcacaacta cacacaaagt ggcgttgaaa gatggaggtg
     2041 caagctaatg tggaaaacga ttctgcgacg tgttttattg atgatcccgc aagttattat
     2101 tttaagtgtt ctgatcttct tattagccca agcgatgccg ggggatccat ttaccggttt
     2161 gatcaatcca aatcaggatc cggcagtgat cgaacagatg cgacaagcag ctggcttgaa
     2221 tgacccatgg tatgtccagt acttccgttg gatcggaaat gctttgcaag gcgattttgg
     2281 tcaaagtttc ttatacaaac gctctgttgc tgacttgatc ggcgaacgga tcatcaacac
     2341 tttatatcta tcgatcttga cagttgtcct tacttatttg attgctgtgc ctctggggat
     2401 gcttgctggc cggtatcaaa attcaatctt ggataagatt gtcgtaatct acaacttctt
     2461 tagttttgct gttcctttat ttatcttcgg cttgatcatg ctatttgttt ttggttatcg
     2521 tttaggctgg ttcccaacaa gtggatcaca aacactaggt ttgcaaggtg gatttatcac
     2581 tcaatggata gaccgtttga aatatattct gttaccatca attacccaag catttttggc
     2641 gactgccgtc acaatccaat atctgcgaag tgaagtaatc gattcgaaat cgctcgattt
     2701 tgtcagaaca gcccgttcca aaggggtacc gacgaataaa gtattcagtc gacatatttt
     2761 ccgaaatgca gcgttgccga tggcttctca aatggggtat gaaatcactt cgttgattgc
     2821 tggttctgta gttatcgaaa agatttttgg ttatccggga gtcggaaaac tatttattga
     2881 ttccatcggc caacgggact ataccgtgat cacatcctta gtattgattt taggaatcgc
     2941 gacgctagtg gggacattac tttcagatat catcatgagt atcgttgacc cgcgtattcg
     3001 gattcaataa aaccaatcag aaaggagaat ggatcgatga gtgaaaaaaa caatacagca
     3061 gttcaagaaa gtattcctcc tatggggata cgaatgattg ctcgagaatt taaaaaagat
     3121 aaaattgcta ttttttcatt aggtttgcta gtggttttat tattagtgat ctttatcggt
     3181 gcgatgctga ccgatcaaga caaagtgatg tatgttagta tcttcgacaa atacgctgca
     3241 ccaggaacag tttcgacaca aggacaaaag ttcattctgg gagcagatga aggcggacgt
     3301 gatgtattag gacaattgat cataggtgct agaaactctg ttacgatcgg atttgcgatc
     3361 acgatcctta cttcgatcat cggggttgga ttagggatca tctctggcta ctacggaggg
     3421 atcattgaca acatcttgat gcggatcgtt gattttatca tgattctacc gatcatgctg
     3481 atcattatcg tcttcgtatc gattatttcc agatacaatg tctggtcctt tatattcatc
     3541 atgagtgcat tttattgggt agctaaagcc cgattattcc gaagcaagac attatctgaa
     3601 gcaagaagag attatgtcag tgcctcaaaa acaatgggaa ccaatgattt taaaatcatg
     3661 ttccgcgaaa tcatgccgaa tctaagttca ttaatcatta ctaatttgac gatgaacttt
     3721 gcggcaaaca tcggtatcga gacaactttg actttcttag gtttcggctt gccggcaaat
     3781 gtacctagtt taggtacatt gatcggttat gcaagtaacg gagaagtctt agtgaatcgg
     3841 caatggatct ggttacccgc atcaatcctt attttagttt tgatgttgag tatcaattat
     3901 gttggacaag cattcaagcg ttctgcagat gcgcgccaac ggttaggcta gtatagaagc
     3961 gaagggggaa ataggaatga agaaaacgat ttttggattt gcagcgctga tgtctgctgt
     4021 cgttcttgca gcatgcgggg gcggaggtac agatacctct ggaaacaact ctggaggcaa
     4081 cggcaataac aaagaggaat taacttttcc aattgcaaca aaaaataatg atgatgcaat
     4141 cgaagacggc gaattagaag ctgcggtcgc aacggacagt cagtttaaag gattgttcca
     4201 gtgggagttt taccaagatt catatgatgc agcttttatg gctccttctc atgaaccgct
     4261 atttgcaaac gatgacgatt tcagaatcac agacgacgga gctgcaacgc ttgatctaga
     4321 tgaagatacg aaaaaagcga caatcaaagt aaaagacaac gtcaaatggt cagatggtga
     4381 agatgtaacg gcggacgatg tgattttccc ttacgaaatc attgggaata aagattacac
     4441 tggtatccgt tatgacgaca ctttccgtaa catcgtaggt atggaagaat atcatgatgg
     4501 aagtgccgac acaatctccg gaatcaaaaa aatagacgac aaaacagttg aaatcgaata
     4561 taaagaagta aacccaagca tgcttcaatc gggtggtggt atctggtcat atgcagcacc
     4621 aaaacatacg ttagaaggtg tagcaatcaa agatatggaa tcaagcgatc aagtacgtaa
     4681 aaatccagtg acttttggcc cttattacat gagtaatatc gttgcaggag aatcagtaga
     4741 atacttgcca aacgagcact actggaatgg tacgcctaaa ttgaaaaaga tcacgatgaa
     4801 atctgtaccg atggcaagtg caactgaagc attgaactct aaattatatg atatgatttt
     4861 ccaaatgcca acagatactt acgataccta taaagaaatt gctggctata caaacttagg
     4921 ccgtgaacaa acttcttata cttatctagg attcaagtta ggtaaatgga atgcagatac
     4981 aaagagtgtg gaatacaatc cagattcaaa aatggctgat aaatcattac gtcaagcaat
     5041 gggctatgca ttagataata atgcagtagg tgaacgtttc tatgcaggtt tgagaagcaa
     5101 tgcgacttca ttgattcctc cagtattcca gtcataccat gatgatgaga tgaaaggatt
     5161 cacacaagat ctagacaaag cgaaaaaact attagatgat gctggctaca aagatgtgga
     5221 tgacgatggt ttaagagaag acaaagatgg aaataaacta acaatcaact ttgcttcgat
     5281 gtccggtggg gaaacagcgc aaccattggc agattactat atccaacaat ggaaagaaat
     5341 tggtttggat gtccaataca caacaggtcg tctgatcgaa ttcaattctt tctatgataa
     5401 attagaaaac gatgatcctg aaattgatgt ttaccaagct gcttggaata caggaactga
     5461 tccaaatcca agtggactat ggggaccaaa tgctgcgttc aactacactc gttatgaatc
     5521 agaagaaaat acaaaattga tcaacgatat cagttcaagc aaagcatttg atgaagagta
     5581 ccaaaaagaa gcatatcaaa aatggcaaca atatgcattt gaagaagcat ttgcgattcc
     5641 aacgttgttc cgtaatgaag tattgccagt caacgaccgt gtcaaagact gggattggtc
     5701 ttatgatgta ccaaacccat gggcaaatgt ttctgttaca gcagattcac gttcataatc
     5761 actaaaaatg accgaaaaag ggcgatgtcc tttttcggtt ttttgatatt tttctgttta
     5821 tttctctaat attcaggtca aggcgctgat ttcatgactt ctccaataaa cggtgttcaa
     5881 agtccagttt ctcggtatta agtcaaattt atgcaaaaat atggaaagcc attttcacaa
     5941 aattttttct tcatactcga aactaaacga atttttcaca acttctcgtc aatcactagg
     6001 attattaaag ctttacttac cttttgaccg aaccatttca aatttgacaa aaaaccagta
     6061 taataaggaa gtatcgaaaa aatatccata aaaggaatgt ggaaaatgga caaccagctg
     6121 acaaaagaac taaaagaaaa ctataacatc gtttttcacg atctaaattt gcttgaacaa
     6181 gcttttaccc attcatccta tgtgaatgag catcgcaatc tgcaattatc ggataatgag
     6241 cgacttgaat ttttaggaga tgccgtttta gaactgatgg tttctcagta tttattccgt
     6301 ttatatcctc atttgccaga aggaaaattg acaaaaacac gagctgcgat cgttcgcgaa
     6361 gacagcttgt cgaaatttgc caaagaatgt cactttgatc aatatgtttt gttgggcaag
     6421 ggagaagaga attcaggagg acgtacgcga ccagcattgc tttgcgacct attcgaagct
     6481 tttttaggcg cgttatatct tgaccaggga ttcgacacga cccatgcatt catcgaaaaa
     6541 gtgatttttc ctaaagtcaa agcaggtgct ttttcacatg agatggatca taaaacaaaa
     6601 ctacaagaag tcttgcaaaa atcaggtgat gtatcaatcg aataccgatt gatcaatgaa
     6661 gaaggtccag ctcatgaacg agtattttgg atcgaagttt atgtagatga tcaattgatt
     6721 ggcactggac aagggaaatc gaaaaaatta gcagaacaag ctgcggcgga aaatgcattg
     6781 gcagcactgt aaaagtaagt gagggaaagc tttgtatttg aaacgaattg aaatagccgg
     6841 ttttaaatca tttgcagaca agacagtcat tgattttgaa aatagcgtca cagcagtggt
     6901 tggaccaaat ggcagcggaa aaagcaatat tacagaggct atccgctggg tattaggaga
     6961 acaatctgct aaaagtctgc gaggcggaaa aatgccggat atcatctttg ccggttccga
     7021 tacccgtaag cagctgaata ttgcagaagt cacagtgatt ttagacaata gtgatcatta
     7081 tctgccattg gagtacaatg agatcagtgt aacccgccgt tatcgacgga ctggggaaag
     7141 cgagtttttc atcaataaac aaagctgcag attaaaagat atccaagaat tgttcttaga
     7201 ttctggatta ggaaaagaat cgttctcaat catttctcaa ggaaaagtag aagcgatttt
     7261 cagtagtaaa ccggaagacc gtcgtgggat ctttgaagaa gcagctggtg tcttgaaata
     7321 caagcagcgg aaaaagaaag cagaacagaa gctttttgaa acagaagaca acctcagccg
     7381 cgtccaagac atcatccacg aattggaaga acagttaact cctttggccg cccagagtga
     7441 ggcagcaaag gagtttttac ggctaaaaga aacactgact caaaccgatg tctctttgat
     7501 ggttgctgaa atcaagacag caaaaaaaga ttgggacaac aaacaagcac agcttgcgaa
     7561 attcaatcta gaattaggca aactatctga gtcgatccaa gaacaagaat ccattttggc
     7621 gaagcagcgt aaagaaaatg cgcaagccga tcgtctgatc gaaaaaaatc agcaagtatt
     7681 attagatctt tcggaaaaac tgaagcagac agaaggacaa aaagatgttt tgcaggagcg
     7741 gacaaagcat acacaaaaaa gctcgcaaga atatcaaact tcattagcag aagcacaaaa
     7801 aaaggttaaa cattttgaaa agcttcaaga aagcttgatg aaagcagcag cagaaaaaga
     7861 aacagagatc caaaaagctg aagcaaatct cataaaaaca cagcaagaat tagaaaaata
     7921 ccaaaaatca acgaaagaat tattggcaga attaagagat caatatgttg atttgatgca
     7981 agaacaagca gctgtaggaa acgaactgaa gtatctagaa cgtcaatata tacaagaaac
     8041 agcaaaaagc aagcagacgt tagccaagca atcggaagta gaagcatcag tagaccgatt
     8101 gatcttacaa aaagaagaat tgacacaaaa gcaggcgcag ctaaaatcat ctttaactga
     8161 aacaaaagag aagttagaaa tgatccaaca aaacgggaaa aagttccaag aagcattagc
     8221 aaaagaacag cctaaaatgt atcaattaat gaatcaagtc cagcagctac gtgctcgtaa
     8281 gaaaagcctt caagaaatcc aagaaaacta ttttggtttt taccaagggg ttcgattggt
     8341 cttgcagcat aaacagcagc tttcgggtat tgtcggagca gtggctgaac tgatcgatgt
     8401 tcctgcagat ttcacgttag ctatcgaagc agctttaggt ggggcagccc agcatgtcat
     8461 cgttgaaaat gaaaaagatg ctcggcaagc catcacgtat ttgaaacagc aaagaggagg
     8521 aagagcaaca ttccttccac tgacgacaat caaaccaaga caattaccgg ctcatatatt
     8581 gacacaagca gcagctgtag aagggtttat agggattgcc agtgaacaag tcagttatcc
     8641 cgatcaaatc caaactgtgg ttcaaaacct gctaggaacg atccttttag ccaaagactt
     8701 aactagtgcc aatgcaatcg cgcaaacgat ccgctatcaa tatcgagtgg tttccttaga
     8761 aggtgatgtg atgaatgccg gaggatccat gacaggtgga gcgaataaac gaggaaacca
     8821 aggcagtttg tttgtacaaa atcaagaatt gaaacagttg actagtgaat ttgaagaagc
     8881 agataaacaa ctccaagcac aagaaaaaaa agttcaggag ctgcaacaag aaacagctcg
     8941 tttagccgaa gaacaagaag ttttgcgtac acgaggcgaa caattacgtt ttgaagaaca
     9001 agaagcgaca aatcagctac aaaacatcat aaatgaactt gaacgttttg aaaaagaaaa
     9061 gcaaatctca acttttgaga cacgtgaact gcagcagttt atcgaagatt acgaaaagca
     9121 aacgaacgaa ttgaaagaca aacaaacaga tcttgaatcg caacgacaaa aaatcgacga
     9181 agaaatcaaa tcgttaagtc aagaaagcga ccagatggaa gccagaagag cacaagtaca
     9241 aagtcaaaaa gcacaagaac aagcagatct tgctgtcttg aaagagcagt ttaatcatct
     9301 gcagatccag ctccgcggtg cccgagtcca aaaagcagag gcaaccgaac gtcaagaagc
     9361 gatagaaaag cagttggcga cattgacagc agacttttct gatcatgaag tcacagaaga
     9421 aagtttggaa aaacaaatta acgaattatc tgctcagcga gaaacattaa aagccgagtt
     9481 ggcaaaagcc aaagagcagc gagatagaag gcaaaaggag atcgataagc ttgaagcagt
     9541 cttggcagag cgtaatcgtg agcaaaaagc acgactgtcg gaacaatcca aattagaagt
     9601 ccaaaaagac cgagctgaaa tgattttaga taatcatttg acctatctgc agtcagaata
     9661 tcagctgaca tttgagaaag cttcccaaga ctatcaagaa acaaccgata tcgaagacag
     9721 tagaacaaag gtttcatcct taaaagaaca gattgaaaaa ctgggaccag taaacttaaa
     9781 ttcaatcgaa caatacgaac aagtcagtga aagacataca ttcttagcaa cacagcgaga
     9841 tgatctgtta gcagcgaaaa accaattgtt tgaaacgatg gatgagatgg atgatgaagt
     9901 gcggacaaga ttcaaagaag tatttgaagc tatccgtcaa gaattcaaaa ttgtctttcc
     9961 aaatatgttt ggcggcggta aagctgaatt agtactgacg gaaccaactg atttgctgaa
    10021 aacaggtatt gagattgaag tacaacctcc tggcaaaaaa ctgcaaagtc taagtttgct
    10081 ttctggagga gaacgagcac ttacagccat cgcgttgctc ttttccatta tccgtgtctg
    10141 tcctgttccg ttttgtatct tagatgaggt agaagcagcg ttagatgaag ccaacgtgaa
    10201 acgttttggt cgttacttga gcgatttcca agatgacaca caatttatcg tagtcacaca
    10261 ccgcaaagga acgatggtcg cagcagatgt actgtacgga gtgacgatgc aggaatccgg
    10321 tgtatcaaaa atcgtttctg tacggatgga agatatcaat gaagaggcga aaatcaacga
    10381 aacgaaagtg taggaacgaa aatgatcaaa ttagtagcaa tcgatttgga cggtacatta
    10441 ttaaatgaac aaaagctgat ttcagatgag aataaacaag cattagcaca agcaaaacag
    10501 caaggggtca agatcgttct atgtacagga cgccccttag ctgcgatggc gcattatctg
    10561 caagaattag gactggtaga tgaaggtgac tacagcatca ctttcaacgg cggtttggta
    10621 caaaaaaatg atactggtga aatcatggaa aagaaagtga tggaagtatc agatatccaa
    10681 cgcttataca aactggctca gcaattggat ctgccactag atgttttgtc tgacaatgtg
    10741 gttttacagc tgcctagtgc cccaaggaag caatccttgt acaatgtgtt gaataagctg
    10801 ctgcaattcc aaccagcgga tataagcgat attacagatg aatttgtgct taataaggca
    10861 gtaatcgctt atgaccaaga agaattagat cctaaaatca aagaaatacc agcagaattc
    10921 catgaaatgt atgagatcat caaaacaaga agtatgcttt tggaatttat gccaaaaggt
    10981 gttacaaaag cttatggtat ttctttattg gcaaaagatc ttggtttgaa acaagaagaa
    11041 atcatggcga tcggtgatga ggaaaatgat ttaccgatga tccaatatgc tggactaggc
    11101 gtagcgatgg agaatgctgt gcctttcgtc aaagaagcag cagatttcgt gacagccagc
    11161 aatgaagaaa atggcgtagc caaagtgatc caaaaatttg tattagagta gggggagtca
    11221 aatgggattt tttgataaaa tcaagcgtgc ttttactggc gaagagaaaa cagaagaagt
    11281 tgaagtacag gagaagtacg acaagggttt agaaaagacg cgtaaaacat ttggtgaacg
    11341 gatgaatgag ttgtttgcca attttcgaac agtcgatgaa gacttttttg aagaattaga
    11401 agaaacactt atcggtgcag atgtaggttt tgaaacagcg atacgaatca ccgaagcatt
    11461 acgtcaagaa gtgaaactca gaaatgcgaa aaaatcggca gaagtccaaa atgcgatcat
    11521 cgagaaactt gtggatctct atgaagcgga aggaatcaat gaagtaaatg aactaaatat
    11581 ccaagaagac ggactaacag ttattttgtt tgtcggtgtt aatggtgtag ggaaaacaac
    11641 aagtattggt aaacttgccc atcagttcaa aaacgaaggt aaaaaagtat tgatggcagc
    11701 agcagatacc ttccgcgctg gagcaatcga ccagttagtt gtctggggcg aacgcgctgg
    11761 tgttgaagtt gttcgtggca atgcaggagg cgatccagca gctgtcgtat tcgatgcttt
    11821 ggaaagagca aagacagagc aggcagatgt tttactagtt gatactgcag gccgactgca
    11881 aaataaagtg aacttgatga acgaattaga aaaaataaaa cgagtaatcc agcgggaatt
    11941 accagaagca ccccaagaaa cacttcttgt attagatgca accactggtc aaaacgcgat
    12001 ggttcaagca aaacaattca aagaaacaac agatgtgacc ggtcttgttt tgacaaaatt
    12061 agatggtaca gcaaagggcg gtatcgtact tgctatccgt aatgaattgc atttaccagt
    12121 gaaattggtc ggtcttggtg aaggaatcga tgacttggag ccgtttgatc caaatgattt
    12181 tgtcgttgga ttgttcaaag gattactaaa agaagaataa cccatgtcta aaaagcagga
    12241 gctgtgacaa aagttgcagc tccttgtttg aatgattgtt tttaacatag ctgtgttttt
    12301 gatgccttca tttttatact tatttgtaag cggttctcaa acaatttcgt tctttttctt
    12361 agactttttg attataatta gattcatatg aattggaggt cacttaatga tgaattttaa
    12421 gcaattatta ttgcatgtca atgcgcgccc ttttatcgac caagctcgat ttggtataga
    12481 acgggaagga cagcgggttg atcttgcagg aaatctagca aaaaccgatc atccagcaat
    12541 ctttggcgat cgatcctatc acccctatat ccaaacagat tttagcgaaa cacaaacaga
    12601 gatgatcacc cctgttaccg attctattcc cgaattattt cagtatctcg ctgctgttta
    12661 tgatgtgact gctcgttcta taccgaaaga agagatgatc tggccattaa gtatgccacc
    12721 tgccttaccg gaaaaagacg aagagatcat tattgcaaaa ttaaaaaatt tcgaagatgt
    12781 cttgtatcga cgttatttag caaaaaaata cgggaagcga aaacagatgg taagcggtat
    12841 tcatttcaat tttgaatttg gcgatgagtt gctaagaaca ttgttcagcc atcaggaaga
    12901 atttcaagat ttttccgaat tcaaaacaga actttatttg aaaacagcga gaaactttat
    12961 gcgctatcgc tggatgatca cttatttatt cggtgcttca ccaatgagtg agaagaacta
    13021 ctttttagat gaatcacatc cgcaagaacc tgttcgcagt attcgcaaca gtgcgctggg
    13081 ctatacgaat catccaaatg tgaaagtttc ctatgcttct atgaaacagt atttagcaga
    13141 tatcgagcga atgatcgaag aagggaaact ttcggaggag aaagaatttt atacaccgct
    13201 tcgtttccga ggcggaaaga aagtcgcaga tttagcaaca acaggtgttc gttatattga
    13261 attgcggaat atcgatttga atccttatgc aagattgggt atcaatccag agcaagttcg
    13321 gttcttacaa ttattcctga tgtacatgtt atggacagaa gaaaaagaag actgtgacca
    13381 atgggtagca gaaggtacga ctcgaaataa caaagtagca ctagaacaac catcagatca
    13441 aacagaattt catcaagaag gtagagaaat tcttgaagga atgaagcaaa tgctggttga
    13501 attggattgg ttggattctc tttatttagt agaggaagca ttgactcaaa tggatcatcc
    13561 tgaacaaacg ttagcagcga aactctatca agaagcacag ctatcgagtc agcaagaagt
    13621 tgctgtggca ttgggacatc aatattataa agaaagccat gaacgtccct atcagttggc
    13681 cggttttcgc gaaatggaac tttctactca gatatttatg ttcgatgcca tccaaaaagg
    13741 tgtccaagtc aaagtattag atgagtcgga tcaatttttg cgtctgcaat tccaagacca
    13801 tgtagaatat gtgaaaaatg caaacatgac aagtaaggac agctatatcg tcccacttat
    13861 catggaaaac aaaacagtaa cgaaaaaagt cttaaaagaa gctgggttcc gggtaccagg
    13921 aggcgcagaa ttttcatcca tggaagaagc ggtaaaagct tatccgagat ttgccgagca
    13981 ggcatttgtg atcaaaccta aatcaaccaa ttacgggtta ggtatcacga ttttcaagga
    14041 aggagctagt ctggaagatt atcaagcagg tttagccatt gcttttcgtg aagacagttc
    14101 ggttttagta gaagaattta tgccgggaac ggaatatcgt ttctttgtga tcgacggaga
    14161 agtccaagcc atcatgttgc gagtccctgc taatgttatt ggtgacagta tccgaacagt
    14221 gaaagaactt gttgaagaaa aaaatagtga ccctttgcgt ggaacgaatc atcgtgcacc
    14281 tttagaattg atccaattag gtgaattaga acaattgatg ttgaaagaac aagggttgac
    14341 gatcgaatca gttccccaag ccaatcaaat tgtttatcta agggagaact caaatatcag
    14401 tacaggtggt gattcgatcg atatgactga tgaattttct gaagcttaca aaaaaatcgc
    14461 cgtttctgcg gtagaagcac taggagctaa gattagtggt atcgatttga ttataccaga
    14521 taaagaaatc gatcctacaa ctgataaaaa agcatatggg atcatcgaag caaatttcaa
    14581 tccagccatg catatgcatg tttatccttt tgcaggaaaa ggcagaagat tgacgatgaa
    14641 tgtattgaaa ttgttatatc ctgaagtatt ttaaaagaaa aagcttttga cagattgtcc
    14701 tatttgatgt caatctgatc aaaagctttt tttgcatgta aaaatttatg tgttttttcg
    14761 ttttaaaata aacgatccca gaagcttttt ttcttttttg gtttttcttt ttcagctggc
    14821 gaagagtttt cttctgggta ttttttttcg atatcaatca caggttcatt tactgcttct
    14881 tttgctgtta agagcaatcc gaattcctca ggatttgcag tgacgtaatc gttgactaca
    14941 gtgaaacggc tattgttttt cgttgctagc tggatatatt ggttttggac agaaaggggt
    15001 agagccccat tcaagagtat ggaagcatct ggatgttttt tgagttcttt taaaaagttt
    15061 tctttgtttt ttggttggat catttcagca acagtcatac taagatagca gcgttccctg
    15121 aatgtcccta aatatttatg ctgttcttca gggttcacta aaggtgtacc ataaagtccc
    15181 ttatccaaat ggctttttac atcatcttgt gccataaaaa ataccctcct tcttctcttt
    15241 gtctttctta cgattatagc atattcccaa taatacctaa aacatatgaa aaagcggttg
    15301 cttttgttca acgattcact taaaataaga atgaaaatca ttctcaatta gaaaggtgga
    15361 ttggatgcgc tacggacgac tagtagcatt attagttatt ttaagtagta tttcattgtt
    15421 catcggagta tcgaatgtac aattgtcaga actgctccag ttagatgggc aaagcttaca
    15481 aatcttgcta gtgactcgtt tgccacgaac gatttgtttg atccttgtgg gagcgaccag
    15541 tagtatttgt gggttgatca tgcaacattt gacccaaaat aaatttgttt caccaacgac
    15601 tgcgggcacg atggatagtg cgcgtttagg tattttagtg gctatgattt tcctacctgg
    15661 tgcatccttg attgtccgat ccttgacagc attttgcttt gcttttgcag gaacattgct
    15721 ttttttatcc cttacgcgat tgttcctcca gaaaaatcaa ttgatgcttc cgttgattgg
    15781 agtcatgtta gggaatatca ttggttcagt tgctactttt tttgcttatc aattccagtt
    15841 ggtacaaaat atgacttcat ggcttcaagg gaattttgcg actgtgatac gaggaaatta
    15901 tgagttattg tatgctgttg ttccattgtt gctcttggtt tggctatttg cttaccgatt
    15961 tacgatcatt ggtctgggcg aatcgtttgc agtaaatctg ggaatagatt accagaagat
    16021 gcagttttta ggcattggct tagtatcatt ggctagtgca gtcatgttga tcatggtagg
    16081 aagcattcct tttatcggag tgatcattcc gaatcttgtc tctagaatat atggagatca
    16141 agtgcacaaa acaattggcg taactgcttt agcaggtagt ttgttcttag tattttgcga
    16201 tcttgtcgct cgcgtgttga tttttcctta tgaaatacca gtcagtgtga tcgttggaat
    16261 catcggtggg gctatcttcc tttatcttct gataagggga cgacgatatg cttaaaaaaa
    16321 agccatctat ttttattggt atgcttgttc ttgttttatt tgttacagga atgtacttga
    16381 cgatccatac atatggaaac tggcattttg catgtgcatt gaggagtaag aaaatttttg
    16441 catttatcct tgtctcgcta gctgtcagca gtgccacaat cagctttcag acaattacgc
    16501 ataaccagtt tttgactcct tcagtattgg gacttgagtc gttatatgtc cttgtccaaa
    16561 cggtcctttt cttctttatc ggaggagtga cgatgcttca gcagacaggt acagtttttt
    16621 tcttattgaa cgttgggctg atggtcgggc tgagtctatt gttatttttc tttcttttga
    16681 aaaaaatgag agcgaatctt tttttattac tgatgtcagg gatgatttta ggtacgcttt
    16741 ttggtagtgt cagtaccttt ttacaagtca tcatggatcc gaatgaatat gatttgcttc
    16801 aaggcagatt atttgcaagc tttggcaata tccagagtca gtatcttttg cctgcttctt
    16861 tgatcattat cggctgctgg tacctgttat ttcgatatcg acatgtgcta gacgttttcc
    16921 atctcggaaa tgaacaagca gtaaacctcg ggatagacac agatcgtttt gaatttttga
    16981 ttttatgttg tgtcagtctt ttgacaggga catcaacggc tcttgtgggt ccagttactt
    17041 ttttagggtt tattgtcgca aatatcagtt atcgtgtctt ttctacttat cgtcatggtc
    17101 agctatttat cggaagcttt ctggtagcta tgctgtttct gacaggagga cagctcgcag
    17161 tagagcagat tttcggctgg aatacaacag tgagtgtcgt cgttgaattt gtcggaggaa
    17221 tttattttgt cacaaaattg attcgcgaaa ggaagagtat cctatgattg atttacaaaa
    17281 ggtcaataaa ctgtaccatg gaaaatcagt ggttaaagat gtacagttaa cgattcctga
    17341 aaagaagttg actgctttta tcggtccaaa tggtgctgga aagtcaacgg tgttgtcgat
    17401 gatcagtcgt ttgataccaa aagatacagg tgaaatctat ttagaccata acgaagtaaa
    17461 ggcttggaaa tccaatgaat tagccaaaaa attatcgatc ctacgacaat cgaatgaaat
    17521 aaatgtccaa atcaccgtga aagaattagt agaatttgga cgatttcctt atacgaaagg
    17581 aaaattgacg acaaaagacg aggaaatcgt tcaggaatca ctggaacacc ttgggttaga
    17641 agaaatagcg gatcaatcga ttgacactct ttcaggcggt caactccaac gtgcgtatat
    17701 tgcaatggtg ctagcgcaag acacggatta tattttactg gatgaacctt tgaacaatct
    17761 agatatgaat tttgcggttc aaatcatgca gattttaaaa aatttagtac aagaaatcgg
    17821 gaaaacaatt gttattgttc ttcatgatat caactttgct gcaagttatg cagacgaaat
    17881 tgttgcaatg aaagatggac agttatttac gcaaggaacg acccaagaaa tgataaaaaa
    17941 agatgtattg gatgaattat acgaaatgga catacggatt tgtgagattg aaggccgcag
    18001 attctgtctt tatttctaaa actaacatta ggagagaaga gatgaaaaaa ttagtagtag
    18061 gtatcttgat tctagcatca tttggtttag cagcatgtgg aaatagcaac aacaccagtc
    18121 aggcagacac aaaaaaaagc agcacacaaa ctgaaactac attgacgata acagatagta
    18181 atggagacca aatcgaggtg ccaaataatc cagaaaaagt cgtcgtattc gacaatggtt
    18241 ctttagatac gatggatgct cttggtgttg gagataaggt agttggagca gctacaagca
    18301 gccttcctga gtatctttca tcctataaaa aagtagaatc agcaggtgga ataaaagaac
    18361 cagacttaga aaaaattaat cagcttcagc cagatctaat catcatttct ggccgacaaa
    18421 gagattttca aaaagatcta agtcaaattg ctccgaccat tttcctttct ttagatgcga
    18481 aaaatccatg ggaatctttc cagcaaaatg tcactgcttt aggggagatc tttggtaagc
    18541 aagaagaagc taaaactcaa ttagaggaat tatctagtgc aatcgatcag acgaaaaaga
    18601 aagcagaagc tactgacaaa aaagcactag tcacacttgt gaatgaaggg caattatcag
    18661 cctacggatc tggttctaga ttcggtttca tccatgattt atttggcttt gaacaagcag
    18721 atgatcaaat cgaagcatcc actcacggtc aaagtgtttc ttatgaatat gtgctggaaa
    18781 aaaatccgga tatcttattt gtagtagaca gaacaaaagc tattggtgga gacgacagca
    18841 aagatgatat ttctgccaat gaactggtag cacaaacgaa tgctggtaaa aatcagcaga
    18901 tcatctccct tgaaccagat gtctggtatt taagcggggg cggtttagaa tcaatgaaac
    18961 tgatgatcga agatgtgaat caagcattta aatagcataa ataacagagg attaaactct
    19021 catactatgt aacaataatg tttcttacat tcttaaatag caagagccta tcctcaaaga
    19081 agttatcaaa aaccatccgt aaaatcgtat tgatgatttt acggatggtt tttatttatt
    19141 tgagaaatct tttttcaacg tgaattcatt atctacatca tacgggttga ttctagaatg
    19201 gggagtggca aaaaatagtg tgatccattt tttcagcatc aagatcgcct cctttgattt
    19261 gaatcaaagg tacaaagcga aacttagata aaacttaaat ttagatattt ttattttgta
    19321 ccgatctctt ctttaaacga tgttccatct gctgcttctc ggcaataagt ccactagact
    19381 agaaaatatg agaagctatt ttctgtccag cgttcttatt actcaaaaca aatcgcagtt
    19441 gtcacaatct cttctaaacg atgttccatc tgctgcttct cggcaataag cccactagac
    19501 tagaaaatat gagaagctat tttctgtcca gcgttcttat tactcaaagc aaatcgcagt
    19561 tgtcacaatc tcttctaaac aatgttcaat cagctgacct tcggtattag ctcaaagcac
    19621 tgatttcaca acctctattt aggcatgtgt ctcagcaagc ggttgatagt tgatgatctg
    19681 catttttcga taaaaatcgg cgggaagctt actccaccgt tttagtaatt gatagaaata
    19741 actctcttct gctttgattt tatactcgct taatatcaat ccaaaactat tcgttttttt
    19801 tgaagctaat tttttataaa tatccaatgc tttggtttta tcttcattga caaagagtgt
    19861 ttttacttca atataagaac cctcgatatt ttgtgtttct tcgataaaat agatgttttt
    19921 tatatattcc ttcatagtga ttcctccaaa gaagtctttt atttgataag tttactctac
    19981 cgaagagttg ttaataatcc gtgaacaaaa agtaattctt tttccaatag ttgttaaagg
    20041 ttttttattt tttatagtat tttttgttat ttaagaaagg aataaggtta aacaaataac
    20101 aggttgcttt ttgggtcttt ttccgttcaa gaaactgaac gaagaaaagg gaaagttgtc
    20161 tcttttgtga taagagaaat cataataaac gaatgactta ctttccaata aattgagaac
    20221 agtcagaacc agacaaatta gttgcatctg atgaataaag tgattattct atgacatgag
    20281 gtgatacaga tgaaattaga agtgacaaaa gaagcacaag aagtattgaa gaataaatta
    20341 gaagcagacg atcaactttt attagatatc gaaaacggtg acggtccatt tgcagaaagc
    20401 caagtcagtt gccaattgga tacggcattt cgattgatca ttgtcaaaaa agatacacaa
    20461 acagatctaa gtctttattc tgtagtggct gatacaccag ttggaccaat caaaatcaaa
    20521 gacagtgcaa tactttacat ggatgatcca tccacacttg ctttagaacc aacttataat
    20581 agtttacaat taaaaggacc aagcggcttg agaaaaggca acttgcaagt tgttcgaaaa
    20641 gactagaggg ataaaatggg aaaattggcg atcatcagcg acctacatgt ggacatcaat
    20701 aaattcggcg aatcagagct gatgcagctt tggcaagttt tgcaaaagca caagatcact
    20761 cggcttcatc tagccggaga tacggctaat aaagtagacc gttgcctagc tgttgtcgaa
    20821 tttttcgtca ataaaggatt atctacgaca tttcatttcg gcaatcacga gttggcagat
    20881 gtgcccaatg aacagatgat ggaccatttt ccagacccac attttttaaa tgaacggtat
    20941 attgctttaa atgagcagac cgttctttta gggatgaatg gctggtacga ctatcagttt
    21001 tccgaattga aagattacga ggcaatcgta cgaatgaagc gtttgtattg gtatgatcgg
    21061 ttcatccagc gtgggaaaac agatctcgag gtcaatgcag aaatgcttgc agctgcaaaa
    21121 aatttgctag accagctgga agcaaaaaaa cttgaggtga ttttatccac tcatttcgtt
    21181 cctaaacggg catttatcat gtatcaatct gctccttatg agcgttggaa caaattaaat
    21241 gcatttttag gatcagaatc attcggagaa ttacttgacc gttattcaaa tatcaaacaa
    21301 gtagtttttg gccatacgca tcgtcgcttt gaagataaat ccatcggtca cacgatttac
    21361 agctgcagac cttttggtta ttattatgaa tggcagctga cccgagattt tgtcttgaaa
    21421 gaacagttgc tagacagcta tgatcctatg aaattacgtg tcctcttgcg tgcccatcac
    21481 ccagcttttc aggcctatca aacacaacat ttgcaagagg aatttgaaca agcgatgaca
    21541 atcgttccgt attgagacag cattagtaat gtgtaaaaga aaataccttg taaaacataa
    21601 ggataagtaa gagcagtaga tccatttatc gtggatatgc tgcttttttt gcggaaaata
    21661 atcagcgaat gtttatttga tcggatgatt tgtaactcgc agagtactag atgcaagcgt
    21721 gtattctttt tttgaacgat aatcacaaaa aaaaatataa tatacatttt ttatttaatt
    21781 ataattaata ttgattgaag tctaggcagt caagtcacat tttgatagat aggaggggga
    21841 cttacgaatt attttaaagg ctatgacagc tgtatttcta gattgtgttt gcatcaagtt
    21901 gcaataaaaa ctagaaatca aatcgggctg ataatcattt ataactaatc gatacatagg
    21961 accaaatata ggtctatgtt cttttatttc ataagtatcg taaaacagaa ttttgctatg
    22021 gattaatcca atcgactgat atgtttagta aataaagaaa gaggaatgtc aatgatgaaa
    22081 aaagaaatcg tattaacagc agcaatgatg ttattcagca tggtagcaag tacgactttt
    22141 gtttctgcaa ctgaagtata cccaaaggaa tataacacag aaggaacgat tacatttgaa
    22201 gcaggagatg agggtgtaac tcctcctgtt gatccagaga atcctgatcc caataaacct
    22261 gtcgatccat cagatcctcc aagccctgga acaggagggg cattatcgat tgattatgga
    22321 tcaaaattca aatttgggac tcaaaaaatt tctactgcgg ataaaacgta ttatgcagct
    22381 gctgatgtga tgaacgatgg gtctagaaaa ccgacatatg tccaagtgac agataggaga
    22441 agtaccttat ctgggtggaa attaagtgtc tctcaaccag aacagtttaa aactgccagt
    22501 ggggatgaac tagttggagc acagctgaaa tttacgaaag ggcaggctgt ttctttggtt
    22561 gatccaacat atacgccgca aacggtgaat tctgaattaa cgttgacacc gggaggaaac
    22621 aatacgttag caattaatgc taaatcagga acaggtgtgg ggacttgggt ctatcgattt
    22681 ggtgcaaatg aaaatgaaaa tcaagatgcg gtacagcttt cggtacccgg taaatctgtc
    22741 aagttagcgc aacaatattc cactaaatta gtttggacat tagaagatac acctaacaac
    22801 tagtttactg aaaagaactg ttaaaaataa atacgtagtc atattgtctt gcgaggtaat
    22861 cgagcaaaaa ttgtcaaagg ctaggctaaa tttgtttgga tacgaatagt tcatctagga
    22921 atttaacgat caggaggaaa agatatattg aaaaagagga ggatcgtgct cattttaagc
    22981 agtctcttag tgactaatat ctttccgatc atagggtact ctttggaatt gaatcagttg
    23041 gagcatggaa atagaagaga cgaagaaagc aaactcactt cgacattcga cagtttaata
    23101 gaatccaacc agacacaaga aagcagtgag gatttaagta tttcgagtag tggagagacc
    23161 actgacaacg tagaagctga gggttcggac aaacaaggac tagaagatgc accaatttct
    23221 gcggttgagc tgcctgacga tcccaatatt atttctatcg ataaaatttt tcaaacacct
    23281 atcggtacta gcacgtccat attggaaaat gggaagttac tgcagttgaa cccagcagaa
    23341 aggtctcaaa gaggagctat ttggtcaaat aagaagatta gtttactctc ggattttaca
    23401 tttaaatctt atttatactt aggaaatcaa cgagatagag cgggagatgg catgaccttt
    23461 acattgactg gcgatcctag aatggctagt aatcccagtc aagttattgg atcgccaggt
    23521 atgggaattg gctcatattc tactcgttct ggccaacctt acattgcgaa tgcgctctcg
    23581 attgagtttg atacgtataa aaatagtggt tcttctgatc gaatggatcg agagataact
    23641 gctgataata gagggcatgg acatgtcgct tttgtcacgc ctaaaccaaa taataataat
    23701 tattctggag agcatactgg cgtgacggta gctcctacat ttctttctaa tggcacatgg
    23761 cgcttgttaa taattaaatg ggacgcggag caaagaagtc ttacttatga tttggaaggt
    23821 gtcggtcgct cttctcggat tatacctgat ctcattaggc agtttggttc tacagaagta
    23881 aattgggggt ttacttcttc aacaggtact ttttttcaag aaaatgctgt cgctgtcacg
    23941 cgacttccat cgaatgtcac atcaacagct gatgtaaaag tcaacgatag tgattatggg
    24001 gccatcgctg aagctggagg aaacgataag ataactatca gaaatacatt gaaggtcgag
    24061 ggggattttc ttgaatataa gaaaatgcag actagtatcg acctcccaca agaattaact
    24121 attcccgagc atatcttgat caatggaaat caaattgatg ccaaagatat cttgataacc
    24181 ggaaatcgag tcacgctaaa tctgacagat tattttattg ctggagatac gttaataatc
    24241 gaattggaga caactttgca ggaagtaatt cctgaaaaag tactcactat gcattttgaa
    24301 taccttgaaa acgggaattt gattgagcaa tcgaatgaaa taaacctaaa gatcgcaaag
    24361 ctgaaggaga tagatatcca tgtttattat aaagataaag acagtcagat tgatattgct
    24421 gaaatgaaaa caatcactgg gaaaatagga gagaagtata aagaaactcc tattgatatt
    24481 gaagggtatg tttttgactc ggattcagcg aatacagaag gcatcttctc cgaaaataca
    24541 gaggatatct atttttatta cagaaaaggc aaactttatc tctcaactgc tcctcaatat
    24601 gtcaattttg gaaaacataa aatatccagt agaccattaa gtgaattcgg acagttttca
    24661 ggtgggttga aaattataga tgaacgggct tttggaagtt ggaaattaca attgaaacaa
    24721 gagaaagttc ttacaaatgg agattttgag cttccagaag ctctttcctt tgttacctct
    24781 gaaaatacaa cggttatagg gacatccgct gttacgattt tcgaaagtga tcaaaagggt
    24841 gaaagcgatt tgtcctctct tttagattct acagctcatc gtggaatcag aataaatatt
    24901 cctgtagaaa accaaagaat cggaaccttt gaggggaaac tatcttggat acttgcagat
    24961 gtcccaggaa attaacagga agagaagaat ataacaaaat tattgagttt caagaagggc
    25021 acaggtacca taggctcttg tgtcccacag agacaagatt ttgttatagt cttctcttac
    25081 atatgattaa aggagcgatt ttcttgagac caaaacaaca attatttata acactcctag
    25141 ttattttagg ggcacttttt aacaatatat cagtgtcagc tagtgcattt aatttttcag
    25201 tgacgccgat aacttcagag aatcaaatcg acaagagaaa aacttacttc gatcttcaac
    25261 ttgatccgga tcaggaagta gaagtaaaag cggaattgag aaatgataca gaaaaagaag
    25321 tgaaaatcga tatttctgtg aatagcgcaa ccaccaattc aaatgtgatg gttgaatacg
    25381 gaaaaaacga gattgaaaaa gacatgagcc tgatctttga tctggtagat tatgtgagct
    25441 atccacagat agtgacgcta aaacctaaaa gtgtccaaac cgttgctttt catgtcagga
    25501 tgccgaatga gcgatttgat ggtgtattgg ctggtgggat cacattccaa gaaatccaga
    25561 cggaaaagga ccaaacagaa actaaggatc aaagcttatc gattgagaat gaatacacct
    25621 atattattgc tttgttgatg caacagacac tgaacgaagt tgctccgaac cttactcttc
    25681 atgaagttaa accagatcaa atcaatgcaa gaaatgtcat cttagcaaac gttcaaaatg
    25741 atcaaaaaac ctatatcaat caagtagtta ttgaaacaaa aattacaaaa aaaggacatt
    25801 ctgaagtttt atatcaagag gaaaaagaag gattgcagat tgcgccgaat acaaattttt
    25861 cttttccaac tgctttaaat ggtcaaccgc taaccccagg tgaatatcac cttacaatga
    25921 ctgttttagg aaatgaaaat gaaaatggaa aattttcgag aaaaaaagga aatactacga
    25981 tcaactatac caatcaatgg gtatttgaaa aagattttac aatagacgga aaagtagcca
    26041 aggaattgaa cacgacggat gttacgatta aaaaagacaa taattggatt tatatcttag
    26101 tagcttcact tttcttattg tttattttat tatgcatact tttgtttgtt ttgagaaaaa
    26161 aagaagagaa agaaaagtaa ggttaagata acaaatagta aatttttatt attgtaggat
    26221 ggttgggctc tttttataac aatataaaat ataccatttt attaataaaa atgcatacta
    26281 gtaaatgata taattctaat aacaggtttg atcgcgagaa aggccaaata aaacgctctc
    26341 caaaatgtta aaaaaaagac aggacgatgt atattataca aacaagaatc gctgacaaca
    26401 gtgactcgga tccaggaaat cagttttatc cccagctagt tggtgaatgc atggaaagta
    26461 atatacgtag aaagagctga tgactaatga attatgagtt ttttttaagc aaagaagatc
    26521 acagaagtta ttcattactt aaatatttag aagcaagctc aaatttatca gagtcaatat
    26581 cgaatgttca agaagagttg tcgctatcga catttctctt gaaaaaaacg atcgataagc
    26641 tgaaacatga tttacaaaag ttcgatctag agaaaaattt gcgagtaacc gtcagtgaat
    26701 tggatatatg tctggaaatt aatggaaaat gttctagcaa agctctgtta tctcgttata
    26761 taacggattc tttatctatg aaaatggtat tggctttctt tcaggaaaaa tatatctcag
    26821 tagaaaattt tgctaaacag catcacgtga gttattctgt ggcttataaa gtattacaaa
    26881 gactaaaaag aaatctaaaa aaatatcaaa ttttttttga aaagagaaag tt
//
LOCUS       DAZAOD010000027        26626 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000027 DAZAOD010000000
VERSION     DAZAOD010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.028"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..206)
                     /locus_tag="ACHDPO_001204"
     CDS             complement(<1..206)
                     /locus_tag="ACHDPO_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3368845.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENA"
     gene            complement(320..412)
                     /locus_tag="ACHDPO_001205"
                     /pseudo
     CDS             complement(320..412)
                     /locus_tag="ACHDPO_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(548..1183)
                     /locus_tag="ACHDPO_001206"
     CDS             complement(548..1183)
                     /locus_tag="ACHDPO_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3368846.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            1695..2837
                     /locus_tag="ACHDPO_001207"
     CDS             1695..2837
                     /locus_tag="ACHDPO_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFN3368847.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            2830..3036
                     /locus_tag="ACHDPO_001208"
     CDS             2830..3036
                     /locus_tag="ACHDPO_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFN3368848.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            3115..4308
                     /locus_tag="ACHDPO_001209"
     CDS             3115..4308
                     /locus_tag="ACHDPO_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3368849.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            4513..5652
                     /locus_tag="ACHDPO_001210"
     CDS             4513..5652
                     /locus_tag="ACHDPO_001210"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFN3368850.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5645..6445
                     /locus_tag="ACHDPO_001211"
     CDS             5645..6445
                     /locus_tag="ACHDPO_001211"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFN3368851.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6445..7272
                     /locus_tag="ACHDPO_001212"
     CDS             6445..7272
                     /locus_tag="ACHDPO_001212"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFN3368852.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7277..7984
                     /locus_tag="ACHDPO_001213"
     CDS             7277..7984
                     /locus_tag="ACHDPO_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFN3368853.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            8084..8950
                     /gene="rfbA"
                     /locus_tag="ACHDPO_001214"
     CDS             8084..8950
                     /gene="rfbA"
                     /locus_tag="ACHDPO_001214"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFN3368854.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            8964..9536
                     /gene="rfbC"
                     /locus_tag="ACHDPO_001215"
     CDS             8964..9536
                     /gene="rfbC"
                     /locus_tag="ACHDPO_001215"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFN3368855.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9558..10586
                     /gene="rfbB"
                     /locus_tag="ACHDPO_001216"
     CDS             9558..10586
                     /gene="rfbB"
                     /locus_tag="ACHDPO_001216"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFN3368856.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10684..11535
                     /gene="rfbD"
                     /locus_tag="ACHDPO_001217"
     CDS             10684..11535
                     /gene="rfbD"
                     /locus_tag="ACHDPO_001217"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFN3368857.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11569..13602
                     /locus_tag="ACHDPO_001218"
     CDS             11569..13602
                     /locus_tag="ACHDPO_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368858.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13646..14926
                     /locus_tag="ACHDPO_001219"
     CDS             13646..14926
                     /locus_tag="ACHDPO_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFN3368859.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            15136..15942
                     /locus_tag="ACHDPO_001220"
     CDS             15136..15942
                     /locus_tag="ACHDPO_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368860.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            15954..17174
                     /locus_tag="ACHDPO_001221"
     CDS             15954..17174
                     /locus_tag="ACHDPO_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368861.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17164..18750
                     /locus_tag="ACHDPO_001222"
     CDS             17164..18750
                     /locus_tag="ACHDPO_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFN3368862.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            18789..20927
                     /locus_tag="ACHDPO_001223"
     CDS             18789..20927
                     /locus_tag="ACHDPO_001223"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFN3368863.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21295..22278)
                     /locus_tag="ACHDPO_001224"
     CDS             complement(21295..22278)
                     /locus_tag="ACHDPO_001224"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFN3368864.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            22656..24047
                     /locus_tag="ACHDPO_001225"
     CDS             22656..24047
                     /locus_tag="ACHDPO_001225"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFN3368865.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            24063..25103
                     /locus_tag="ACHDPO_001226"
     CDS             24063..25103
                     /locus_tag="ACHDPO_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFN3368866.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            25122..26207
                     /locus_tag="ACHDPO_001227"
     CDS             25122..26207
                     /locus_tag="ACHDPO_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFN3368867.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            26240..>26626
                     /locus_tag="ACHDPO_001228"
     CDS             26240..>26626
                     /locus_tag="ACHDPO_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFN3368868.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKH"
BASE COUNT         8656 a         4451 c         5413 g         8106 t
ORIGIN      
        1 gcattttcat ttccaattct ttgaaaaatt gcttttaaaa tatcttcctt tgaatcgaaa
       61 tgatgataaa tagcaccttt agaaagtttt gtttcattga taatatcttg caatgatgtg
      121 ttatcatatc ctttttcaca aaacattttt gtagaaacat ctaaaatgag ttttactgtt
      181 tcttctggat atttatttcg tgccataact tacctccaat acaaaccgtt ggtctgatta
      241 aagtatatct tagtatttta tgcttgtcaa tataaagact tgcaatttta taaaaatgca
      301 gaatgcaagc ctttttcatt tattctacaa tcttccagtt gctttcctta tgcggtgtca
      361 attcatactg tgatacctgc gttgcctttg cctgatttac cacaaatcag attttatccc
      421 tttcttcctc ttgattgccc acaacagaaa agaaaaagcc ctgtcaagag ctttgccacc
      481 attggtggtg ctttgcactc ttgatcgggc tttttgtttg ctgtatcttc tcgcaagagg
      541 aaaaaagtta ctcgtcctca tcatcaaaat tgttattcct taatacttct cgtaacagtt
      601 ccatatcttc ttttgagttc gggtttatca ttttcacgac ttgataaggt gtcttatact
      661 tatgtccctc tatgctttcc ccaaacatat ccatactgta taaatcatca tagcggtcta
      721 ataatttttg aaacttcaaa tgctggataa attctttgat tgggtaaagg tcggacgctt
      781 caatgctttt cccgttgata tagtctgtaa tatattcccg taacttttct aactcatatt
      841 ccagccattc ttcctcgctg tcaaagaagt tatcatagtg tccatgtttc agttctgcat
      901 ttagacgttc ttcggctctt aaaaactgac agacttcctt ttcagattga ttgacatact
      961 tccattctcc cgacaacaat tcattgggcg taacgtccag cacttccatt atcttttcca
     1021 gcgtttcata ggcaggatag ttcaaccctc tttcaatctt ggaaaggctc tgcatattga
     1081 taccgatttt gtccgcaagt tcctgttgtt tcattcccct aaattttctt atggtctgta
     1141 tattatttcc taaatggctt attttcattg cataaccctc catatctcgt tatatcttcg
     1201 ctattataag tctatcatgc ttaatatgat ttgtaaaggc aaaaaaagat attgacaaat
     1261 aagcatataa gaattactat gttcttgtaa tcgaataagc acaatagaat gaaatataaa
     1321 aacattcaaa aagaaatacc tatctgatta aatccgtaga tatgaatatc ggttgaaatg
     1381 gaacttgtta gaaaaggcaa aacagaactt gctgacaaag tatttctgac acggtggcgg
     1441 aagcctctca ggcttaccgc catgacacct tgtgtcaagg ggaagaaatg ctttgtcggc
     1501 tggcgagcct gcgagccttg tctgtgcccc cgttatctaa caggggggca ctatttcaca
     1561 aaagacaagt caaaaaccat acacccccaa acctgtgagt agtaatgaga ggttttaaga
     1621 agatagtaca tatcacactt tttgaaaggt ggtttacagg tatttcaagg ctattgtggg
     1681 attggaggaa tacaatgaac aatttagaat ttgcacttga aatgaagaac aaacgtcttg
     1741 ccagcggtct ttcacaagga gaacttgcaa gtcttaccca tgtatcaaga tatagtatca
     1801 accgctttga gaacggaaaa gctaacgcca gcaaggaaac acagaacatt atcctgcgtt
     1861 gtctgaatta ctatatctgc gataagcctt tttatctgct cgttgattat ctgtctgtcc
     1921 gttttccaac gactgacgca ttggaagtta tccgaaaggt gcttggcatg aaagcagatt
     1981 attttatcca ttatgactat gggtattatg gctataagga gcattatgct tacggggaaa
     2041 tcaaggtcat ggcttctgat gatgaacaca tgggcgtatt tttagaatta aaaggggcag
     2101 gctcacgcaa catggaatat gtcttacagg cacagaacag ggactggtat tcattcttaa
     2161 accgctgtct tgactgtggc ggtgttatcc gacgttttga cttggcaatc aatgatatgt
     2221 gcggtctgct ggatattcct gtgctatctg aaaaatacag aaatggtggt gcggaatgtc
     2281 gctgtaaaaa ctatgaaaat gtacaaggtg gaaaattaag cggaaaaaac cgtaatttag
     2341 caagtaccct ttatatcggc tcaaaggcaa gcacaaaata tttctgcctg tatgaaaaac
     2401 aaaaggaaca ggcaacgaaa aagaaacata ccgatattat caaccgtttt gaaattcgtc
     2461 tgcgtgacaa aaaggcggta caggcagttg aagaactgtt attgacgtat aaccctcatg
     2521 ggctggtgtt ttatctcatt accgattttg tggaatttcc tgactatcca ttgtgggaga
     2581 tattcatttc ccatgacagt ttaccttttg aaatgaaccc tgtacctgtc aatatggaac
     2641 gcactctgca atggctggaa agacaggtca tgccgtcaat cgtgatgata gaggaaatcg
     2701 acaggctgac aggttcaaac tacatgaaaa tgattgatga atgtacccac ctttctgaaa
     2761 aacaggaaat gcttgtggaa cagatgtgta cggacatatc agacgtaatc gaaagtgagg
     2821 gggtgtttta tgagtaatac acaggatatt cccgtatggg aaaaatacac ccttaccatt
     2881 gaagaagcgt caaagtattt ccgcattgga gaaaacaagt taagacgatt ggcagaggaa
     2941 aacaaggacg ctggctggct cattatgaat ggcaaccgca tacagattaa acgccgacag
     3001 tttgaaaagg ttattgataa attggacgca atctaatgca aatgagcctt gtatgtgtta
     3061 tgatgaacac aagtcatatc aaggctcttt ccaacaagga aaggagcaga caccatgaaa
     3121 gaaaaaagac gggataacaa aggtcgtatc ctgcatactg gagagagcca acgaacagac
     3181 ggaaaatact tatataaata tgtagacgca ttgggaaaca caaaatatgt gtatgcttgg
     3241 agattgacac ccacagaccc gacaccaaag ggaaaacggg aaaaaccctc acttcgagaa
     3301 ctggaacagc agataagacg ggatattgag gacggtatcg acagcacagg caagaaaatg
     3361 acgctttgcc aactctatgc caaacagaac gcacagagga caaatgtgaa gaaaagcaca
     3421 cagaaacaac gggaacaact catgcggtta ttaaaagagg acaagttagg tgctaggagc
     3481 attgatacga taaaaccctc tgacgctaaa gaatgggcgt tacgcatgaa agacaaaggc
     3541 ttttcctaca ataccattaa caaccataaa cgctcgttaa aagcgtcatt ctacatagcc
     3601 atacaagatg attatgtgag gaaaaaccct tttgatttca agctaagtga agtcatagaa
     3661 aatgatacca aagagaaagt cgcattgaca gaggaacagg agcaagcctt attgtcattt
     3721 attaagacgg acaacgtgta tcacaagcat tatgatgatg tgctgatact gttaaagaca
     3781 ggacttcgta tctcggaact gtgcggactg acagtagccg acattgattt caagaatgaa
     3841 gttgtgatta tcgaccacca gttactaaag agtaaggaac agggctatta tattgaaacg
     3901 cctaagacga aaagcgggat aaggcaagtg ccattaagca aagaaacgat acaggcattt
     3961 caacgggtta tcaacagccg accaaagata aagtcgatag aggtagacgg acacagcggt
     4021 tttgtgttta tcaatccgaa aggtaatcca aaagttgcca ttgattataa cgccttattt
     4081 atccgtatgg taaagaaata caacaagcac cacaaggaca atcccttgcc acatattaca
     4141 ccgcatacgc tacgccatac attctgcaca aggctggcaa gcaagaacat gaacccgaaa
     4201 gatttacagt atatcatggg gcattcaaac atcagtatca caatgaactg gtacgctcat
     4261 gcgtccatag ataccgcaaa atcagaggtt cagcgtctaa tcgcatagaa gtatttacca
     4321 cgattttaac cacgattgac agggaaaata taagaagata gacctagata tgcgaggttt
     4381 accacaaaag caaaatgccc gtagagccga taaaataagg ctttgcggac atttgagaag
     4441 atataaaaag atagtcaaaa agacatatat aatttataat aattatgact cttaattaaa
     4501 gtaggtgccc atatgcttgt ttcttttagt atggttataa gattttttct gacaatttta
     4561 ttatcactga tattaacacc tgtattcaaa atcatttcag tacaaacagg tatggtcgac
     4621 aaaccaaatg aaagaagaat aaataaagtt ccaatgcctt cagcgggcgg actgcctatc
     4681 tttatttcat ttgttatatc gactttattc ttattccgta aaattatccc tcaatcgtat
     4741 attgtaccga tcttgattgc ttctttagta atcatagtca caggagtgct cgatgataaa
     4801 tatgagctga cacctaaaca aaaaagtata gggatcttga ttgcttctct tattatttat
     4861 tttgtagcag atatacgtat tgattccttc acgcttcctt ttattggata tatccaacta
     4921 ggctggctta gttttcccgt aacgattttt tggatcttcg gtatcacgaa tgcggtcaat
     4981 ctgattgacg gtttggatgg gctggcggca gggatttcat tgatcggttt aattacgata
     5041 ggaatcattg gatatttttt cctccatgct tctacagtgt atattccagt tgttattttc
     5101 tgtcttgtag caagtattat cggttttttt ccttacaatt tttatccggc aaagatttat
     5161 ttaggcgata caggagctct attcctaggg tttatgatgg ccgtcctttc actacaaggg
     5221 ctgaagaacg tgacttttgt ttcatcgatt tctttgctga tcgtcatggg agtgccggta
     5281 acagacacgt tttttgctat cattaggaga aaagcaaacc gtgtttcttt ttctacagca
     5341 gataaaaaac atcttcatca ccgactaatc agtttaggct ttactcataa aggtgctgtc
     5401 ctgacgattt atgcgatggc tttgatgttt tctttcacag ctatggtcat gaattatact
     5461 ggaagaatcg gaacgatcat attgattatt gccatgttgt ttgctgcaat tttattattt
     5521 gaattgattg gtctgatcaa tgagaaacat cagtttattt taaaaacatt gcgattttta
     5581 gggaataaag agtaccgtac gcaagtaaaa cagaaatatt tgaagaaatg gaaccgtcat
     5641 atagatgaat aacaaattaa accagccgat ccttattagt attgtgacgg caaacagtga
     5701 taaaattttt cggacactag ataattttat ttcaactgta aaagatgaaa cagcagtaaa
     5761 aatccgaatt tttgacaaca attcacttcc cgagtacaaa aaaagactaa cagagtatag
     5821 gaaatatccc tacatcgata tctattttca tgatgaaaat tccggatttg gttatggaca
     5881 taatcacaat ctgatagcta gcgattctcg ctatggcatt atttgtaacc cagatatttt
     5941 agtggatgaa gagacagtta cagcattggt cttgttattg aaagaacatc cggaatgtgc
     6001 gatgttagca cctaagattc ttaatgaaga tggaacaact cagcacctca tccgtgagca
     6061 gctggctgtt tttgattacg ttttgcgctt tgtgcctttc aaatgggtca aaaaaaagtt
     6121 tgacaaacga ctggctgtgt ttgaatgccg aggattgcct actgatgcta atagttatgt
     6181 acggatgatc tcaggtagtt ttatggtagc tgatattgat aaatttaaag agataaaggg
     6241 gtttgatgag cgtttcttca tgtactttga agacaacgac ttgtgtttga gttttgaaaa
     6301 agcaggttac aagttattgt acacaccctt ttatgcagtt atccattttt acgggaaggg
     6361 tgcgcatcga aatgcaaaac tgtttcgcgt gtttttgact tctatgatga aatttttcaa
     6421 taagtggggg tggcgttttt tctgatgaaa ccagaaatat tagtagtcgt tgtgctttat
     6481 cagcaactat tcagtcaatc tccagcttat ggaccattaa gcaaagcact tagcgaaaag
     6541 caaattcagc ttattattta cgataatagt cctcaaaggc agcaaaatga gctgtttgaa
     6601 aaagaaaata tcgtttatca tcatgatccg caaaatcctg gtttagcggt ggcttataat
     6661 tttgcgttgt ctcaagcaga tgaaggaaca cgttgtctcg tcactctgga tcaggatacg
     6721 aggctagtcg acgattattt tgaactattg cgtaaagtaa cctttacaga tgaatgtgtt
     6781 gctgcagttc cgatgatttt ttctgggagc cgacaagttt ctcccctata ttcagatcgt
     6841 tatatcaatc gtacagctca agcagtagaa gttgaaggcc caacagctga acgaatcatg
     6901 gcaatcaatt caggtgttgc ctggtctgtc aaatttctaa aaaagattgg cgggtttaat
     6961 cctgcttttt ctttagattt tttggatcat tggctgtttt ggaaagtgga tcagttggaa
     7021 aaaactgtgg agatccttcc tgtacgaatg gaacatgatc tttcggtttt agactatgaa
     7081 aaagtttcaa gtaatcgata ccgttctatt ttacaagcag aaaatcgatt ttatcatgaa
     7141 tatgatcaaa ggcatttatc cagtcaccga cgacaattat tgttaagaac agctaaacag
     7201 ttcttgaccg tcaaaaaccg gcatatctgg cggatgactt tgcgctcata tgttaagaat
     7261 tggaaggtgt gaattcgtgc gttcggtttg tatagctacc tttaatggag gcagatattt
     7321 aagagagcag ttagatagta ttttatctca gctttcagca gaagatgaag tagtcatttc
     7381 tgatgatggg tcagtagatg atacatggga tatattaact gaatacgcag aaaaagataa
     7441 gcgaatccag cttttttcgg ggcctcgtca aggattgatc gctaattttg gttatgcgat
     7501 ccagcagacg aaaggagatc taatcttttt ggcagaccaa gatgatgttt ggttggagac
     7561 aaaagtgaaa aagatcactg actattttga gcagaatccg gatcagctag tagtagtttc
     7621 tgatttaatc attgtggaca gcgagctgca agagatccat gattcgtatt tttcgtttcg
     7681 aaattccaaa gaaggatggc ttaataatgt gataagaagt cactatattg gtgctggtat
     7741 ggctttccgg tcttctttaa aacccgatat tttgccgatc ccgtcagaag tgccgatgca
     7801 tgatatgtgg attggtttgc tgggaggaaa gaagactggg ttcctaagag aaccgttaac
     7861 tctgtaccga agacatgatt taaacgcgag tgagattgaa acacattcta aattacggca
     7921 aaaaatttct tggcgtgttc atctgattac ggcgttgatc aaacgaaaat ggtttaaacg
     7981 ttgataaaag atgtttaaat ccttaatatt tccatgacaa atataacaat tgatgagata
     8041 ataacaaagt gaaatttgaa atcaaaaagg agagcagata tccatgaagg gaatcattct
     8101 tgctgggggc agcggaacac gtctgtaccc tttaacaaag gcaacatcga aacaattgat
     8161 gccgatttat gacaaaccaa tgatttatta tccaatgtct actctgatgt tggcgggaat
     8221 caaagaaatt ctgattattt caacgccaca agatacacca cgtttcaagg aattatttgg
     8281 aaacggaaat gatttaggac tgcagatcga atatgcagta caagaaagtc cagatggatt
     8341 ggcacaagcg tttatcattg gagaagaatt tattggagat gatagtgtct gcttggtatt
     8401 aggggacaat atttactatg gtggcggtct gtctaaaatg ttgcaacgag cagcttcaaa
     8461 agatacaggc gcgacagtat ttggctatca tgtcaatgat ccagaacgct ttggtgtagt
     8521 agaatttgat gagaatatgc aagctttgtc gattgaagaa aagcctgctc agccaaaatc
     8581 aaattacgct gtaactggcc tttattttta tgacaatgag gtaatttcta tcgctaaagg
     8641 tatcaaacct tcagaacgtg gagaactaga gattacggat gtcaataaag catatttgga
     8701 taaaggaaaa ctatccgtag aacttatggg acgcggattt gcttggcttg atacaggaac
     8761 acatgaatca ttgcttgaag catctacctt tatcgaaaca attgaaaaac gtcagaactt
     8821 aaaagtggct tgtttggaag aaattgctta ccgtatgggc tacatcgata aggaacaatt
     8881 gctggccctt gcacagccat tgaaaaaaaa tcaatacggt caatatttat tgaatttggc
     8941 cgctgaataa ggagtcctta cagatgaaag taacagatac aaaattaaca gatgtcaaaa
     9001 tcgtagaaat ggacgtcttt ggcgatcatc gcggtttctt cacagaaagt tattcaaaag
     9061 caaaatttgc agaacatgga ttgaaatatg actttgttca agacaaccat tcactatcag
     9121 ctgaagctgg tgtccttcgg gggcttcatt tccaaaaagg agaagctgca cagacaaaat
     9181 tgattcgggt agtcactgga gcagttttag atgtagtagt ggatatccgc aaaggtagcc
     9241 cgacttatgg tcaatgggac ggatttatct tatctgaaca taatcatcga cagttgcttg
     9301 tacctaaagg atatgcccat ggattcgtta ctttgacacc aaatgtgaac ttcctttata
     9361 agtgtgataa ttactataat gcagaagcag atgggggcat cgcatttgat gatccagatt
     9421 tagcgattga ttggccaatt gatccatcaa gagcgattat gtcggaaaaa gatcaccgtc
     9481 atccgacatt aaaagaattt gaagcagaaa atccatttgt ttacggagaa atctaagaat
     9541 taaggagaaa ttttcttatg aaaaacatca ttgttaccgg aggtgccgga ttcatcggct
     9601 ctaatttcgt tcattacgtg gtaaacaatc atccagaagt gcatgtcact gttttggata
     9661 aactgactta tgcaggaaac aaagagaact tggctggact tcctagcgat cgcgtagaat
     9721 tggtcgtagg agatgttgca gatgcagaat tagtggaccg tctagtaaaa gaagcggacg
     9781 cagttgttca ttacgcggca gaatcccata acgataattc attaaaagat cctttcccat
     9841 ttgtacaaac gaatatcatt ggtacgtata cacttttaga agcttgccgc aagtatgatg
     9901 tacgctatca tcacgtatct actgacgagg tttacggcga tcttccatta cgtgaagacc
     9961 tgccaggaca tggggaaggc gaaggagaaa aattcactgc ggaaacacca tataatcctt
    10021 caagtccata ttcttctaca aaagctggtt cagatctgtt agtaaaagca tgggtgcgtt
    10081 cttttggctt acgtgcaacc atttcaaact gttcaaacaa ctatggtcct tatcagcata
    10141 ttgaaaaatt tattcctcgc caagtaacga atatcttaag cggtattcgt ccaaaattat
    10201 atggcgaagg aaagaatgtt cgtgactgga tccatacgaa tgatcattct tcagcagtgt
    10261 ggctgatttt gacgaaaggc agaattggcg aaacctatct gatcggtgca gacggtgaag
    10321 aagataataa gaccgtgatg gaattgatct tagaaatgat gggtcaacca aaagatgcgt
    10381 acgaccatgt aaacgaccgt gcaggacacg acttgcgtta tgcaatcgat tcgacaaaat
    10441 tacgggaaga gttaggatgg aagcctgagt ttacgaactt ccgtgatggg ttggctgaca
    10501 cgatcaaatg gtacgaagaa catgaagact ggtggaaaaa agaaaaagag gccgttgaag
    10561 cagcatatgc caaaaatgga caataataca gagaaaatgt cactgtatta atggaaaaac
    10621 acatgtgagg caggcgctcg cctgtctctt ttttaaaata aaaatcaagg agcggataat
    10681 catatgtttt tattaactgg aggaaatggg caactaggta cagaattgcg ccatttatta
    10741 gatgaaaaaa atctgcaata tgtttcaaca gatgcaaaag acttggatat cacagatgcc
    10801 gagaaaacaa tggcttacat cacagaatta aaacctgatg ttattttcca ttgtgcagct
    10861 tacacagcag tagataaagc agaagaagaa gcaaaagaat tagatgagaa gatcaatgtt
    10921 gatggtacaa gaaatgtagc acttgcagca aaagctgtga atgctcaatt cgtctatatc
    10981 agtacagact atgttttcga tggaaaaaac aaaaatgtag aatacgaagt agacgaccaa
    11041 acgaatccac taaatgaata tggtcgtacg aaattattag gcgaaaaagc agtagaagag
    11101 attttagaag actattatat catacgaact tcttgggttt tcgggatcta tggacacaat
    11161 ttcgtcttca cgatgcaacg cctagcggaa acccgcgaca aactgactgt agtaaatgac
    11221 cagtttgggc gaccaacttg gacacgtact ttggcagaat ttatggtata tgtcatcgaa
    11281 gaaaaagcac catttggtat ttatcatttg tcgaacgaaa atagctgttc ttggtatgaa
    11341 ttcgcaaaag aaatattgaa agatacagat gtagaagttg cacctgttac gtcagaagaa
    11401 tttccgcaaa aagcaacacg tccgcagtat tcagtcatga gcctgaaaaa gacagaagag
    11461 ttaggatttg tcataccaac ttggcaagaa gcacttgcgc aaatgctgga agctgccaaa
    11521 aaaatgaata agtaatttcc ttttatcaaa tagaatttgg agcatgatat ggaaaaacaa
    11581 acaagaagtg cacgacgaaa agaaaagcca aaagcgaacc aggcagattc gaatttggtg
    11641 cttgacctgt ttctaaaact ccgctatctt attggcgttt tagtcatcgt ggtcatcgtt
    11701 acttttaatt taaacggaag ttcacttggt gtttgggata aatatgtgtc gcaaagagac
    11761 gatgggaaaa aaactgatgt gatttttgga cagaatcggg aagtgcggtc agacgaatgg
    11821 ctggtgcaga caccttttta cctctcacaa gctgaagagg actttccgtt ggtgaacgag
    11881 gattattcat taaacggaca aaacatgatc attgcgtata attctcctgt aaaggatatt
    11941 acggttatcg gaaaaccatt caactgggga ttctttttcc tcggaagaga tcgaggactt
    12001 tccttttatt gggcgatgaa attagtcgtc atggtcttgc ttggattcga agtactgatg
    12061 atattaacga agagaaaaaa agctctatcg ctaatcggtg catttgcgct gacattttct
    12121 ccagcagtcc agtggtggtt catgcaacat gtgggcgatt tgattttctt tactttggga
    12181 ctgatgactg ctttttatca ttatttctac aatcatgata aaaaatggct acgaacgttg
    12241 atgatgcttt tggtggttat tttcggtatt gggtttattt tagtgattta cccagcccat
    12301 caagtgatgc tggcgtactt gctgattttt tattttgttg gcctgcttat ttactatagc
    12361 aagaaagttt catgggatct gttggatgta gtgttgattg gaggggcagt tttatttatt
    12421 ggcggagtca tggttcattt ctggctaacg tcaaaagacg cattgttagc ttctttgaat
    12481 accttatatc caggaaaacg ggtaagtact ggaggaaagt ggacgattgg cgaatttttt
    12541 tctttcctta caaattggaa aattcctttt gaagatatca actattcgaa taactctgaa
    12601 gtggccctgt tctatcactt ttttccaact gtattcctag caagtccatt tgtgttattt
    12661 ggcaaaaaag atagcgaaca aaagttactg ggacgtattt tgatgatttt ttgtctgttt
    12721 tctatctttt ggattaccgt tgggttgcca aaatggctag cagaaatcac tctgctgtct
    12781 tatgttcctc cattaagagc catccttact tttagttttg cggcttgttt attatcgatc
    12841 tggtttatcg cttatatttg gagagaagat gttattccta tttggtataa attcattttg
    12901 ttggcagtaa atgcatggtc ttatttctat gcgattacgc attcgaaaat ggataattat
    12961 ttttcggatt ttgaaaccat cgcagttgct gtgttgggaa cagtgatttt agcttttgca
    13021 ttatttggct ggagacgctt gttttacctc gcttttgccg ccttagttat cgtatctggc
    13081 tttttcgtca atccagtcgt agaaggtaca ggagcgattt ttgaaaaaac actggcaaaa
    13141 gaaatccaaa aaatcgatca acaagatcct ggtaaagttt ggttgtctga agatgaatta
    13201 tataacttca ccccaacatt gggagtgaaa tccttcaata cagtacgctt ttatccagat
    13261 atagctgcat ggaagaaaat cgatccgaaa gaagaatacg agaagtatta taatcggtat
    13321 gctcatacaa gagcttttat cgctaaggaa gatacaaagt tcattttaga tcgtccagat
    13381 atgttttcgg tcacgttgaa ttttgaagac gcagaaaaat tagggatcga ctatgtgatc
    13441 agtaaacgac cattaactga ttacaaccaa ttatatgaag cgcagttcac gcagctatat
    13501 ggaccggata aagacggtta tatgattttt aaagtagaat atccggatta tccagatgta
    13561 ccacaaacac aaactcagga aaatcagcta gtcgtacagt aataggctag ctgagaataa
    13621 tcctgaaatg ttagtagaaa ggagagtgga gataattcaa gcaatcgtac aaaaatttgt
    13681 caacaaaatg agtgtcggtt tcttgctttt gttactgacg ctagtctttt ttgtttggac
    13741 agcagggtta ggttttccag caactttgtt tatatataac aatagttcat tacttatcgc
    13801 ttttagtgtg gctattttgc tcattttaaa tgtttataaa gcaaaaggcg tcgattttct
    13861 ttatctaggt gttgcgcttg cccttttcat tttcttttct tactttcggg aattaagaaa
    13921 tgagtcttta tttggagact tactgtttcc tttgattatt ttattttgtt tagtaattaa
    13981 atggatcgag tggacaaaat gggatcgcgg tatttatctg attgtctttt cggtcttcct
    14041 cggaatcacg ttatatcgtg tatttacaga gatccaagta ccagaaggac aaagcatctg
    14101 ggctccaggc aattcgcttt ctgatatttg gatcaatacg aatataatcg gaagttcttt
    14161 gatgactctt gctttattga tcagtggatt tgccagttct tttgaacgat ggtatgtacg
    14221 aatcatcggt gcagtagcag ttgttgcagc ttttctcggg atttgggtct gccaatctag
    14281 aggtgcatta gtcgcgttga ttgtttttgc gatattggat cttttaccta aatcgttgat
    14341 gcgtgtcatt cgtgcgccat ttattgctta cacggttacg attcttttag ctttgccgat
    14401 ttcttatctg gcggctgtct ctgaaaaagt caatttgttt accggtcgag aagatatttg
    14461 gcataaattc tatcagacgc taggagaaaa atctgaacaa attttactag gaatgaaaac
    14521 atttatcttc caacgaggaa accaattttt aggaaaccac aatagttata attctatttt
    14581 gaatatctat ggattgatag gatttgggat tgctgctttg ctgcttatcc tttttattgg
    14641 tcgcttaacg ttgaaagcag atttatccaa cgggcagatg acttttatct gggccttttt
    14701 tgcggtgatg atgcagtcat ttatggagga tacattgact tcatacccat gggttccgat
    14761 tatttatatc ctgttggcta tggccgttca tcgatatgat gaaccagaag ttgcggagga
    14821 attctatgtt atggaagagg catatgacga tatgacttat gatgatacat cttatgagga
    14881 acaaccagat agcgctcatt cttccaggat ccaacgctat cattgatagg cacaaaatac
    14941 gagagaggct gtgacaaccg tcgcagcctt ttttggttta ttgcaattgt ctagcatctt
    15001 ctgtaaaata gaaacgttag agaaaatctt gtatcataga aaattaagaa agaaataaga
    15061 acgcagctcg gtaccaaaaa tatggtaaaa tggcacttga ctgtaattca ctgaaaatcg
    15121 cttggaggaa cacaaatgtt taaagatttg tatttattta tgaaggacat ttatcagaac
    15181 agaaaattat tgctacagtt ttcgatcaat gacttcaaat caagatatgc aggatcgttt
    15241 ttaggaatct tatgggcgtt tatcaatccg ctatttactg tattgattta ttggctggta
    15301 tttggtgttg gactgaaagc acaaatgatc gatgcaaaat acccatttat cgtatattta
    15361 gttaccggga tgattccctg gttcttcttc tcagatgcat ttgcatcaac tacggttgtt
    15421 tttcgggaat atacttattt agtaaagaaa gtcgtattca atattcgtat cttgcccacg
    15481 acgaaaatcc tatccaatct gtacacccac ttattcttca ttctgattgg catagctgtc
    15541 gcgcttataa atggtatata tccttcagca atgtctttac agctgattta ttatttattt
    15601 tgcatgtgtg ctttcttgac aggattgact tggctgacgg catcgatcca accattttta
    15661 cctgatatca tgcaattaat tacgatcgtg ctgcagttga tcatgtggac attaccgata
    15721 ttatggagcc ctaatcagtt tgattcaggt cttgtaagca tattgaaatt aaatccgctg
    15781 tactatgttg ttcaaggtta tcgtgagtca tttttaagtg aagcttggtt ctgggagcat
    15841 ggaacatata ctttgtattt ctgggttttc acgttagtaa tgttcgtaat cggctctgca
    15901 gtgttccgta gattgaaacc acatttttca gatgtgctgt aaggagaata gctatgacag
    15961 aatatgcaat tagactaaaa gatatcacaa aatcttataa tatgtacgca aaaccttcgg
    16021 atcgatttcg tgaagccctc aatcctttta agaaatccta tcatgatgta ttttatgcgt
    16081 tgaaaaacgt gaatgtagaa ataaaaaaag gtgagatgat cggtttcgtg ggagaaaacg
    16141 gatcgggaaa atctacaatg ttgaaaatca ttacgggagt actgacacca acatccggca
    16201 cgatggaaat cgaaggaaaa atctcagctt tgctagaact aggatcagga ttcaatcctg
    16261 agtattctgg ctatgaaaat atctatttaa atggaatggt tctaggattt tcaagagaag
    16321 aagtcgatga aatggtcgat gatatcattg aatttgctga catcggagac catatttatc
    16381 aacctgtaaa aacttattca agcgggatgt tcgttcgtct agcttttgct gtagcaatca
    16441 atgtgaatcc cgatattttg attgtggatg aagcattggc agtaggcgat cttgaatttc
    16501 aactaaaatg tatggaaaaa tttacagaaa tcaagaactc gggaaagacg attttattcg
    16561 tttctcatga tatcagttcg attcgtcgtt tttgtgatcg ttcctattgg ttgaaaaacg
    16621 gagaagtcgt cgaatatggc gatacgatgg aagtaacgac gaattatgaa aactttttaa
    16681 agaaaaaatc agttaaaaca gtggatcgga ataaaaacca agtagaacgg ttcgccgctc
    16741 cagatatcgt cgacgtgacg aaagcggaat tgttggataa agacaaaaat ccggtggata
    16801 tgctggaaca aggagaaaaa ctatacgtta aagtaactta tgaagtaaaa gatgatacaa
    16861 tcaaaaatcc ggttttagga attgcgctac gaacagtcga caatttttat gtatgcggac
    16921 ttaatactct actagatggt atcaagattc cttggaaaaa aggagagaat atcttttatc
    16981 tggagtatga aaagttaggt ttgttagctg gtgaatatta ttttgacgtt gcggtctttg
    17041 aagaaaatgc aacggttcct ttggtatata agacaaagta catgaacttg tttgtcagcg
    17101 gttcttatat cggagaaggc atcgtggtct tagaccataa atgggaagaa gggactcata
    17161 gcaatgaaat atgattttga aatggaccta gatgaacaaa gcagtgtggg aaaaattgcc
    17221 gcacagatca aaccaggaag taaagtttta gagtttggtc ccggaaacgg ccgattaacg
    17281 aaacatttaa tcggagcaaa acaatgtgaa gtgagcattg ttgagttaga taaggaattg
    17341 ttcgattttg tcagcgaatt tgctcaagat ggattttatg gtgatatcga aagttttgag
    17401 tgggcaaact attatgctgg acagacattt gattacgtct tgtttgcgga tgttttagaa
    17461 catttggtag atcctggaaa aacattgaag aaagtcagag aatttttgaa tgaagaagga
    17521 gagatcctga ttacattccc taacttggcg cataattctg tcatgatcga tttgttcaat
    17581 aaccaattgc cgtgggcttc ttatggtctc ctagatgaaa cccataattc tttttatact
    17641 catgatggct tccaaaaagt ttttgaaaaa gcgggattat tcattaatat tgaagattat
    17701 ttgtacttag ctgtaggtga tacagaatta aaatcaactt atgaagaatt gccggaagct
    17761 gtacgctatg atttcaaaat gcgaccattt ggtgaagtct accaatactt tttctcattg
    17821 atgaaacatc cagtagcaca aagttccatt gcagagccac aaaattctaa ttatgtaaaa
    17881 gtgttagaag taacccagca aacgaaacaa gatgaaacaa tccaacaaat accattcaat
    17941 aatttcacag gggaaaatga gacactaagt ttccccgtat cagaaacaac agaaagaatg
    18001 gtgtttcgct tcgcgcaaca acctagcttt atcgaattca gcgcagaagc tgccggagaa
    18061 aaactaacat ttatcgattc gaatgctgta gtcaaaacag taaatgattg ttatttgttt
    18121 gatgggaaag aattaccaga gttcgttcta acggatattt ctgggaaaga agtgactatc
    18181 cattgtcact atcgctttat cggggaattg acaccaacaa tgaaagaatt gttggaaacg
    18241 attcgtccca tggctgaagt cacaaagcag ctttctgaga aaaatgacga attagaaaga
    18301 gaaaatcatc atcttcttga ggaaaataca agactagacc atacgttaaa aacaaccaca
    18361 aatcgctatt gcacattgtt ggaaagtgat gaatggacaa taaaacatag actaggacga
    18421 cgtaagaaag aaacttcgaa aaaaatccaa gaaaaagaac tttctatatg tattgacgag
    18481 aaaatctggg atgcagaaac aaaaatatta aaaatcatcg gatggggaat cgctaattcg
    18541 gatcgccagc ccttgtccta taagttatca gctgaccaat cgccattttt cgaagcaatt
    18601 cctgtttcac gagaagaagt caatcaagca gaacagctcg caaaaggaac agaagcggga
    18661 tttgagttac gaatcctttg cgagcaagaa cgttcattct tagtggaagc agtagctcaa
    18721 aatggccaat catggatcat tgaaatgtaa ataatgatta acttataaag ataaggagta
    18781 aacgaatcgt gcaaaaaaaa gaaattgccg tatttatcga tcaaatcact cgtgaacggg
    18841 ccactggcga tttgcttatt gtgggctggg caattgatga agtgaccaaa gaaatcccta
    18901 cgataaaggt agaaaaagaa aatgtgattg ctgaagcaac acatgtcgta agattggata
    18961 tcaatcattt atataatctt gatgttaaga cccaaagcgg ttttaaggta cgtttatcag
    19021 ggaaaatgag aggaaaagcc atcttagact tccaaacagc gagacatcaa aatggcatag
    19081 ctgtgaaatt aaacggtaaa tacccttatg atgacggcat tgaatcttca tgggaaagaa
    19141 aaaaaagatt actgaaaaaa gggataaatt atgcaaggac tcatggcgta aaaaaagcga
    19201 tccgtcgggt caaattggaa ttgaagccag gatcgatcga ctatgcagag tggatcagtc
    19261 gtcatgagaa accagatttg aaagagcaaa ggaaagaagc acaaggattt gcgtaccgtc
    19321 cattgatttc catacttatg cctgtctata acgttgaaat caaatggctc gaaaaatgca
    19381 ttgattcggt actggatcaa acgtatgatc attgggaact atgtatcagt gatgatgctt
    19441 ctactgatcc agctatccga aagtgtctgg aatcctatca agcaaaagat gatagaatca
    19501 aagtcgtttt ccgaaaagaa aatggacaca tcagtctggc aactaattct gcattggaaa
    19561 tagcagaagg agaatttata gcactcttag ataatgatga tgaattaccg ccatttgcat
    19621 tatatgaagt ggcaaaagtg ctaaacgtac atccagaact ggatgtgatc tacagtgacg
    19681 aagataaaat cgatgcagat ggcaatcgct ttgatccgca tttcaaagca gactggtcgc
    19741 ctgatacatt gatgggaaat aattatatct ctcacttagg cgtatatcga acaagcattg
    19801 ttaaagaact tggcggtttc cgtaaaggct atgaaggttc tcaagattat gatttggtcc
    19861 ttcgtgtgac agaacaaatc cctgcagatc atatttacca cattgaccga gtcttgtatc
    19921 attggcggac gatcccagga tcaactgcaa gtaatggcga agccaaaagt tatatctatg
    19981 attccggagt gaaagcattg acagatgccc tgtctagaag aaacatcaaa ggaagcgtac
    20041 gtcctggcag aatttctgga ttttatgaga ttgcttatga cgtcttgcaa gaggatttgg
    20101 tcagtgtgat cattccaacg aagaatggct atgaagatct aaaaacttgt gtggattcga
    20161 tcatcgaaaa aacgtcttat tcaaattatg aaatcattat tgcggataac ggaagtacag
    20221 atccaaaaat gcaagaatta tttgcagaat acaagcatca gctgaaagac cgctttatcg
    20281 tagaattgat tgacattcca ttcaattatt ctcgaattaa caatttagca gcagaaaaag
    20341 caaacggcaa atacttttta ttcttgaata acgatacaga agtgattgag ccagattgga
    20401 tgacggtgat ggtttcttat gcacagtttg atcgaatcgg ctgtgtagga gcaaaactgt
    20461 tttatccaga tgatacaacg cagcatgcag gagtattatt aggaatcggt ggtgttgcag
    20521 ggcatgcatt gaataactat gatcgaacac attgtggtta tttcggccga ttggtcattg
    20581 acgtcaatta cttagcagtc actgcagctt gtatgatggt caaggcagct gacttcaatg
    20641 ctgttaacgg gtttgatgaa acattagaag tagcattcaa cgatgttgac ttgtgcttga
    20701 aagtttatga actgggtcgt tacaatgtct atgcacatca agcagaattg taccatttcg
    20761 aatctaaatc aagaggttat gaagatactc cagaaaaaca aagacgtttt gctggtgaaa
    20821 tcaaaaaaat gcaagataaa tggccagcat atattgcgca tgatccattt tacaatgata
    20881 atttaacaaa agaaggaatc ggcgactttt cgttgagacc agattaaact ataataaaaa
    20941 gctgttatgt tgtgattcgc tcgcacataa cggcttttta tagttttttg tcaaaaaaag
    21001 gcagaaggtg ccgactcaaa aaaataagtc gaggttggga cagaagtgtt taactccgag
    21061 aaataagaag aaattcacga aaattgcttt tcaaattttt gtgaatttcg gcttatttaa
    21121 gaagaagttg cttctgctcc caccgtttat tcgtttttaa agaatgagac aaaagtgttt
    21181 cttacttttg tcccacgctc ttattcatgc tcagagcgcc aatagataca aaatcatagc
    21241 caaagtttca cgaaccctag ctgtcaaaga atcgatattt tattttaata taggctattt
    21301 taaaataaat ggtttaaggt attcctctac aaaagccact ctatcaatta tcatgggttt
    21361 aaaataagaa gtgatggaga taaccagatt gttcttagcg tcaatataaa gaacatttcc
    21421 actattacca attgctgaat atatttcgtt ctcagaatct aatacccacc ataaatagcc
    21481 atatctcata ttttgtaagt cttctaaagc actggttcta ggtttgaaca tctcgtttat
    21541 ccacatgggt ggtacgattt gttttccttt atacatccct ttatttaggc ataatacacc
    21601 aatttttgcc agatcacttg ccgataaaca caaaccatat cctgccgtcc cgatatttag
    21661 tggatcacaa aaccagacat tggttttagg agacttatcc attgtaaact gcttatgttc
    21721 ttcagctgtt tcagcataat aattgacatg gtttggtatc cctataggat caaatagata
    21781 cttattggca aaatcaacag ttgttagctt acttgtctga tacaacaagc cagttaatat
    21841 gtgtaaacag acagtttgat agttgaattc gccggttata ccttttcttc ctcccaataa
    21901 atctagtgat gtttttgtcc aatcttcact tgaacagact tttgtccatg gatcgccttt
    21961 acatttgtag ggtgctttca ttgttagcaa gtgcttgatt gtaatagcgt aaatagtttt
    22021 ctccccgcgt ttcactttat actctggaaa ataatctaat actttatcat cgatactttt
    22081 gattaatcct tgctctaaag caatgccaat cagcaaagat acaatacttt tcgttgctga
    22141 catgatatga caagtatcgt cttttttata accattccat tcatctgtat aaacttctac
    22201 cccatcctta tatgcgacaa tttgacatat atttggttgt cgaaaaccaa taaaatcatg
    22261 caactcttgt ttattcataa gatattacct cactttcttc tataagcata atgtcattaa
    22321 aaatcgattt caattttttc gattcttcac gtaatacagg tattcttatg gactagacag
    22381 cgctttggga agatggattc tctgaaaaat ataaaggttc actttatgag tggataaaaa
    22441 aagcagcaaa tacttcgact tctttaattt accaacatta gtgaaaatcg attcatctgg
    22501 agatttgtaa tttagagtcc ttgtcttgat tagaggtgta taaagctttt tattagacat
    22561 ttttaaattc cattacaatt tgcttataaa ctaggttttt aaaggtgact atggtaagat
    22621 aatagagata ttattttgtg attaggagtg tatatatgaa taaaaatgga gaatggagtg
    22681 ctgcacgacg gatattcatt atattaatgg atgttattgt atacaatgca gcaatatata
    22741 gtagtttctt actgaagttt cgtggagaga tcccattacg aaatttagaa actttccaac
    22801 actcagcaat tattatttca gtgattttta ttgcgttgaa cattttgttg ggtgcatatg
    22861 ttttttataa tcgaatgatc agtgacatcg tgtttgtcac agtcatcggt caggtattga
    22921 tgacactagg gatcatggta gtgacttttg cgggccgctg gtttgctttt ccacgtcttg
    22981 ttatcttact ttcatttgtt ctcggtacgc ttttcttaag tatctatcgt attctcgtat
    23041 ataaacttta tttacgcgta agtcgagata aaaaggtcgt cattattggg ttagaaaagg
    23101 atgtcgcacc agcaatccaa aattttggtt caaagaaaaa caacaaacat aaagtcgaag
    23161 cagtcattct tgataactat tatgcaaaca tcaaaaatat gattaaagac atcgatattg
    23221 tctatcttgc ttctcatatc gaagaaactg aaaaaatcaa aatctatcaa ttagttacta
    23281 aaaatgaaaa aaaattgttt ttgaatacaa catttgaaaa cttgacattg atcaatccaa
    23341 atattatgaa tttcgaagat gaaagtatta ttgaagcatc tggatttaga atccaacctg
    23401 aatatgaact attcaaacgt ttgtttgata tcatcgtttc acttgtttta ttagttattg
    23461 cttcaccatt tatgttattc acagcaattt tagtcaaagt gacatcaccg ggaccaatca
    23521 tctataaaca agtgcggatc acaaaaaatc aaaaggaatt ttcaatctat aaattccgct
    23581 cgatgaccgc cacagccgaa gcaaaatctg gaccagtttt agctaagagc aatgatgcac
    23641 gagtaacgcc tgtaggtaaa tttattcgag ctgtccgctt tgatgaatta ccacaaatct
    23701 tcaatgtgct gaaaggcgat atgtcgatcg taggaccacg tcctgaacgt cctttcttcg
    23761 tcgatcagtt caatgcagaa aacccttatt actacttacg gcataatgtt cgtgctggta
    23821 tcactgggta tgcacaagtc tatggaaaat atgtctctga ttacaacagt aaattacgtt
    23881 ttgatttact ttatatcaaa aaatattcat tgatgcttga tttaaagatc ttgctgcaaa
    23941 ccatcaagat cctatttgat aaaatgtcct ctcaaggact tgaagaagac gaaaatgtga
    24001 tctcattggc agaaattgct tttccgaatg aaaaaatctt tcgctagttg ggaggcgtaa
    24061 aaatgaacaa tccgaaattc agcataatcg taccagtata caatgcagaa gcaactattg
    24121 gtcgaacgat tgatattcta aaagaattgg attatgaaga gtacgaagtc gttttagtaa
    24181 atgatggatc aacagatcaa acacaggaaa tcattcaaga actgattgaa aatgatgaac
    24241 gttttgaatt gattactacg accaatcaag ggcccggatt agcaagaaac gaaggaataa
    24301 gacagtcaaa aggagaatat ctcttattct tcgatgcaga tgacacgcca gtaaaaacga
    24361 tcttgtcaga ttatgatcat ttgctagaaa agagtccaaa agcggatctt gttgttagtt
    24421 cgtttgtttt tcgtacaatg gacgagggaa gaatcgtttc cgaaaaagaa aacttagtta
    24481 cagaatgtca ctatctaact cacgaagagt ttataaaaga catgtatcag ttaatgaatg
    24541 aacagttgat gtatgttgta tggaacaaat gctatcgtag cgatattctg aaaaataacc
    24601 aaattctatt taaaacttat aatagttgtg aggatcgaat atttaactta cattattatg
    24661 aatactgtca tcaagtgatc atgaacccaa aagtagaata tatttatgaa tttgaaggtg
    24721 ggaaggggat cactaatcaa taccgaccta acaagttcga aacatttaaa gaattctatt
    24781 cattagcaaa tactgtaaca gacgatatta ataaagacgg tatggcggcg cttcttttaa
    24841 aagggacaac ttcagttatt ttttctattt atagtacctc tgcaagaact tcaaaagaga
    24901 agaaagacga agcaaagcag atattgagtg atccagtgat ccgagaagcc aagcaaattg
    24961 ctaagacgga ttcttcagca aaaaaaataa caaagttgct ttacaatatg ccagctccac
    25021 tatttttatc tgctgtaaaa gttggaagct tcgttgaagt gaaaatgcca gggttaatgg
    25081 ctgctttgaa gcgagtatat tagttaatgg aggaaaatat aatgaaaaga attttgcatt
    25141 ttcagggacg aatgggttta ggtggagcag agtctttcat gatgaattta tatcgtaaaa
    25201 ttgatcgtac aaactatcaa tttgattttt tgatttatga agattatgca gatgttcaag
    25261 actatcattc agagattgaa agattaggag gccgtatttt tgttgtacct aatcctaaga
    25321 aaaatatttt taaatattta atagaagtga ataagttact aaaaaaagaa tctttttcta
    25381 tagttcacaa tcaggtttat tttggcgggg gaattaattt atggttagcc aaaaagaatg
    25441 gaatcagaca gagaattgct catagccatg caactgaaga tggaaaatct caaaatattg
    25501 taatgaatgt attgcgtaaa tttttaacca aattgttgtt acaaaatgca acagactacc
    25561 ttgccgttag tcaagaagct ggtgaaagtc tgtttcaaaa ccaccccttt gagatagttc
    25621 ataatggtat tgatttagag ctttatagta aaaattcaga agctaaggtt aataagagaa
    25681 aagaattgga tatctcaatg agtacttttg ttgtgggaaa cattggacga ttagagaaac
    25741 aaaaaaatca atcttatttg ttagagattt ttttagaaat actaaaaatg aattctgatt
    25801 cttacttgat tttagtaggt gaagggtcac ttagaaataa actgaaagcc aaagcagtag
    25861 aattggatat agagaaaaga gtaaaatttt taggagaaag aaacgatatt cccgagttat
    25921 tatctgtgat ggatgttttt gtaatgcctt ctctttatga aggtctgcca atggttggat
    25981 tagaagcaca agcagcaaaa ttaaaattag tcttagcaga tactatttcc aaagatacaa
    26041 agttaacaaa taatgtggat tttgtatcat tagatgaaac accacaagaa tgggcaaaaa
    26101 aagtaataaa agagccgtat gctaataaaa taacacaaga actaaagagt tatgatgttt
    26161 cgtacactac tgaacaaatg gagagtatat atagtagaga tcattaaaaa tgttcaagat
    26221 attttaggag tgattatttt tgaaaatatg ttatttgata ttggcataca atgatattgg
    26281 caacttaaag agattggtca atcgattgaa cgaaaatgca gtttttatta ttcatataga
    26341 taaaaaaact gatatagaac catttattga agcatttaaa tcatatgata atgttgaatt
    26401 tttatgtaat aaaaaccgtg ttaaaattta ttggggtggt ttttccattg tacaagcaga
    26461 aatcaattta gtaaagagag cattacaaaa tgagaaatat ttaaaatatg tattattatc
    26521 tggtgctgat tatccaatca aagataatga gtatatttat aattatttta aaaagaatag
    26581 ttcagtggag tttattcgtg gaatagatct agatcaaatt aaacat
//
LOCUS       DAZAOD010000028        25632 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000028 DAZAOD010000000
VERSION     DAZAOD010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.029"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            70..2130
                     /locus_tag="ACHDPO_001229"
     CDS             70..2130
                     /locus_tag="ACHDPO_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFN3368869.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2213..2782
                     /locus_tag="ACHDPO_001230"
     CDS             2213..2782
                     /locus_tag="ACHDPO_001230"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3368870.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(2957..3763)
                     /locus_tag="ACHDPO_001231"
     CDS             complement(2957..3763)
                     /locus_tag="ACHDPO_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368871.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3901..5415
                     /locus_tag="ACHDPO_001232"
     CDS             3901..5415
                     /locus_tag="ACHDPO_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFN3368872.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5818..6801)
                     /locus_tag="ACHDPO_001233"
     CDS             complement(5818..6801)
                     /locus_tag="ACHDPO_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFN3368873.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6806..7453)
                     /locus_tag="ACHDPO_001234"
     CDS             complement(6806..7453)
                     /locus_tag="ACHDPO_001234"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFN3368874.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7538..8170)
                     /locus_tag="ACHDPO_001235"
     CDS             complement(7538..8170)
                     /locus_tag="ACHDPO_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFN3368875.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8186..8737)
                     /gene="coaC"
                     /locus_tag="ACHDPO_001236"
     CDS             complement(8186..8737)
                     /gene="coaC"
                     /locus_tag="ACHDPO_001236"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFN3368876.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8734..9471)
                     /locus_tag="ACHDPO_001237"
     CDS             complement(8734..9471)
                     /locus_tag="ACHDPO_001237"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFN3368877.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9468..10457)
                     /locus_tag="ACHDPO_001238"
     CDS             complement(9468..10457)
                     /locus_tag="ACHDPO_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFN3368878.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10715..11257
                     /locus_tag="ACHDPO_001239"
     CDS             10715..11257
                     /locus_tag="ACHDPO_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFN3368879.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11274..12359
                     /locus_tag="ACHDPO_001240"
     CDS             11274..12359
                     /locus_tag="ACHDPO_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368880.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12371..13177
                     /locus_tag="ACHDPO_001241"
     CDS             12371..13177
                     /locus_tag="ACHDPO_001241"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368881.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13178..14005
                     /locus_tag="ACHDPO_001242"
     CDS             13178..14005
                     /locus_tag="ACHDPO_001242"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368882.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14002..15075
                     /locus_tag="ACHDPO_001243"
     CDS             14002..15075
                     /locus_tag="ACHDPO_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3368883.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15503..18199
                     /locus_tag="ACHDPO_001244"
                     /pseudo
     CDS             15503..18199
                     /locus_tag="ACHDPO_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            18264..18764
                     /locus_tag="ACHDPO_001245"
     CDS             18264..18764
                     /locus_tag="ACHDPO_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3368884.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            18776..19270
                     /locus_tag="ACHDPO_001246"
     CDS             18776..19270
                     /locus_tag="ACHDPO_001246"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3368885.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19291..20100
                     /locus_tag="ACHDPO_001247"
     CDS             19291..20100
                     /locus_tag="ACHDPO_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFN3368886.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20097..20918
                     /locus_tag="ACHDPO_001248"
     CDS             20097..20918
                     /locus_tag="ACHDPO_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFN3368887.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            20969..23068
                     /locus_tag="ACHDPO_001249"
     CDS             20969..23068
                     /locus_tag="ACHDPO_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFN3368888.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23065..24183
                     /locus_tag="ACHDPO_001250"
     CDS             23065..24183
                     /locus_tag="ACHDPO_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFN3368889.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24222..25100
                     /locus_tag="ACHDPO_001251"
     CDS             24222..25100
                     /locus_tag="ACHDPO_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFN3368890.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25246..25443
                     /locus_tag="ACHDPO_001252"
     CDS             25246..25443
                     /locus_tag="ACHDPO_001252"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFN3368891.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            25427..>25632
                     /locus_tag="ACHDPO_001253"
     CDS             25427..>25632
                     /locus_tag="ACHDPO_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368892.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVS"
BASE COUNT         8102 a         4457 c         5424 g         7649 t
ORIGIN      
        1 atataatgaa atcatcttat gaaaattact acttcatgtt tagacaagag tagggaggac
       61 taagaataaa tgtgttcaaa aagacgttca aaacaactaa ataaacacgc ttgtcgttta
      121 gataaggaac ggtcgtgttc tgaaaaacac tacgttaagt ttatgatgcg cacgatgctg
      181 atcagtttat ctgtaggtgt ctatatgcat gtacccgttc aggcaacgac acaaaccatc
      241 aaggtcgtac gtacctctgt ttctgagacc actgattccc ctatcactat tactcatact
      301 ttcactgatg caaatggaaa acagctactt cctgcattga cttcctataa taaagtcagt
      361 tatcctccaa cgataaacca ctactggtta attcctaaca aaacattatg gacatcggaa
      421 accggaagca gtgtgccgct ttctatcttt tccgatatga ctgatcctac aaaaggtgat
      481 cagttaaaac agatcactga tattttgaat catgctttga cagatataaa ggacggtgga
      541 agcgcacaag tttcttatgt atatgaaaaa gattattcac agtttgaaag aaagaaaatc
      601 gatgttctgg cagggacaaa agtttcgata tctgatctgg tagaaaggct gaagaacgca
      661 gatggaacac aaggagatat gtccaaagta atttcaaaca atgggaatat cgtggatacg
      721 actaatacag gaacatctac tatttccttg tcctattttg atccaattgc tttaaaaaca
      781 atgactgcat ctgctgtgat ccatgttcgt gctgatcaaa cagctatcaa aggaaaagat
      841 cttcacttaa gaacaggaga gagttacgcc cctaaagatc ttgttgaata tgtaacaaaa
      901 agcgatggaa cttcaggaaa taaagaagaa atcaaaatga acgggacagt agatactaca
      961 actccgggag aatatcccgt tgtattaact tatatagact cgaaaacatc aaatgtggca
     1021 gaaacaacag ctgtagttta tgtagaagca tctgctgctt catcgactgt catcactcat
     1081 tttatagata gtcaaacaaa taaagaactt caagcagaaa cacatatgag tagtgtaaat
     1141 cgtattcctg atttgcgcct acctgctgaa ttttctgatc gagtgccaaa tatagattta
     1201 tcgacttatg aacaaaatgg gaaagtcact tctatttctg attggatgca agcaaacgga
     1261 ttagacagaa aaagtcactg gtcggagatc cttgaagtac ttcactcaga actgatgaat
     1321 aataggaagc aatcaggagg ggaaattacc tttacttatg tttatatacc agacaatcgt
     1381 tcattagaag gtcatgatct tattgttcat ccaaacgaaa aaataaacaa agaagagttg
     1441 atccaatcag caacaaattc cttaggtaaa cccgtaccgt taaaggatgt atcggttaca
     1501 atcaatgaag taccattgga ggatggttat ttgaccaaac aaacaggtga ttttacgatt
     1561 atgtatagtt atcatgaccc gtattcactc caagaactcc atgctcagtc actattacat
     1621 gttttaccat taaacaaaca gatagatcaa aaagaacaaa aaagacaaga agaaagcttg
     1681 tcagaaaaaa aacaacaaat ggctcatgca gtttctccaa cagggaaagt aaaacaaaca
     1741 agaagcctag agttagcaag aatatctaga aaaatctcag aatctaataa aacgataagg
     1801 caagaagctc atttggcccc acaagtttct ggattggaaa atgaaatttt agagcctaaa
     1861 ataaaacaac aatcagaaaa agaatttgtt gctaaacagt cggaagatca gaaggaatca
     1921 gatgaccaga aggaaacgaa gaaaaaacgc ttgtcaacta ttgattccac cgatgagcat
     1981 ctgcagccgc aagtaccact tcctagtccg ggaacacccg cacctggtgg aggtattcct
     2041 tcttctgctt taggagattt catgcgaggt atggcaggaa catgggtata cgctaatcga
     2101 aatgaatttg acgcagatga ctggttctga tttatatctc tatctgttat agtcaaataa
     2161 gtagctgagt catatgttat ttggcataat ggagacgagg agggatagaa aaatgttaga
     2221 taaaacgtta ccttacgcag aaatctggat gacaagacca cttcaacaaa atgttccaat
     2281 cacgccttta gcggaaggtt ttgaatttcg attttatcaa aaagaagatg aatctgcttg
     2341 ggcggagatt gagacttccg ttggggaatt tcaaacgaca gatgaagcac ttgagtattt
     2401 tcaacaaaac tttgctcctt atcctgaaga acttgaaaga aggatgtttt ttgtagagac
     2461 aaaaaaagga gaaaaagtag caacctgtac cgcttggcga aaaaaatcaa gagagcaagt
     2521 gtatccggtt tttcattggt tagcagtgaa atcagattac caaggaaaag ggctcgcaaa
     2581 agcattgact gccagagtct tgcaagaatt tcctaccctc catacggacg gaccaatcta
     2641 tcttcacaca cagacatgga gccatcaggc gattgctctt tataaaaaaa tgggttttac
     2701 ttttattgct gaaaatctag acggcacacc taatccagat tatgaaaaag ttatgcaggt
     2761 tttaagtaaa ttagataaat aacgaaatgg tgaaataagt cctcagtatt gggataaaaa
     2821 acgaaatagt cattcctcat atcttacttt tttgagttaa tactatcgga taactaatgg
     2881 catgccatac attcaaaaaa gaaggggcag tgacaaaagt attgtcactg ccccttctct
     2941 tgttttttag catgttttat cgtttgattt ttttaggaat aaaattcttg atgaacgtaa
     3001 atttttggta atcgtttcga ctatagaggt aaccaaatac actgaaaaca actgctccaa
     3061 taaaattaac aaataaatcc ttcatagtat ccatgattcc cacgtctaag taaccatttt
     3121 ggatgattgt tttatctgtt ttaccatctg cattttgact ttcaatgatt gtccgagtga
     3181 tatctggaac atgatagaca gtgtttccgt ctttacttaa ctccacacta ttgatttgct
     3241 ggatgatcgt atctttttgc atatcgaatt gcagtaattt atctgctgaa aattccacaa
     3301 actcccacat aacaccaact gtcatcgaaa aacagaagga aacaactgct agtaataaag
     3361 gagtcaagtt catggttttt gtatttttat tgagcaaata aacaagggaa aagccgacac
     3421 ccccagctaa aaatccgctg aatgcatgta gaaaagtatc ccacattgaa aaatagccat
     3481 aaaaatcact taactctcct aaaactgttg aactaaaaat aaaagataac aaaatgattt
     3541 ctagcatatt tggaatctgt atctttaata tcttttccag aaaataaggg atttcaaata
     3601 aaattaatgt cagtaataaa agcattgtat ttccccagtg ttggttccag acctgatcca
     3661 ctagcataat aacgacgatg atacgtaata aaatatagat tccgtttgtg attctacctg
     3721 cagtttttgt actgttcgta aaaaaggttt tcaaatgatt cataaaataa ctccttcatg
     3781 tatatcctta attatactaa gaagcgtgtg tttaccaaag ctatatgact taaagaaaaa
     3841 cagagttgat attgtgaaaa aaatcactta atatagtata aggagaaaag ggggatacaa
     3901 atgaaaaaat tagttgctgg tttattaaca gccgttgcac ttcttgctat gagcgcatgc
     3961 ggcgcagatc agaaaaatac agcgcagaca agttctagta cgaaggaatc tgccgaagta
     4021 tcatcaggcg cttctgaaca agtatataca gatccaaaag aaatgaaaga atcttatgat
     4081 gtcgtgatta ttggagctgg tggtgcaggg atggcagcag ctatcgaagc aaaagatgct
     4141 gggttgaatc cagtaatttt ggaaaagatg cctgttgccg gaggaaacac atctaaatca
     4201 tcaagcggta tgaatgcttc agaaacaaaa tttcaaaaag aagaaggaat caaagactcg
     4261 aatgatgcct tctatgaaga aacgctaaaa ggtggtggag gaacgaatga taaagaaatg
     4321 cttcgatact ttgtcgatca ctctgctgat gcggtcgatt ggctagatca aaacggtatc
     4381 aaactggaca acttaacgat cactggaggg atgagtgaaa agaggacaca tcgtccgtct
     4441 gatggctcgg ctattggtgg atacttagtg gaggggttat tgaataacgt ccatgagcgg
     4501 gaaatcccta tttttgtcaa cgcagatgtg acagacatta agaaaaatgg ggaaacggtc
     4561 aatgaagtga ctgtacatgt tcaaggagaa gaaccaaaag aggtcaccgg aaaagcaatc
     4621 gtagttacca caggcggttt tggtgccagc aaagaattta ttgaaaaata tcgtcccgat
     4681 ttagctgatt atattacgac aaatcaagaa ggatcaactg gagatggtat caccatgatt
     4741 gaaaaattag gtggacaaac cgttgatatg gataaaatac aaattcatcc aactgtgcag
     4801 caggatgagg gggtcttgat tggtgaggtt gttcgcggag aaggagcaat cttggtcgat
     4861 caagagggga aaagatttgt caatgaaatg gatacaaggg ataaagtatc tgcagcaatt
     4921 acagcattgc ctgaaaaatc agcttatttg atttttgacc aaggcgtgcg tgatcgtgcc
     4981 acagctattg aattttatga ccaaaaagga tatgtcacaa ctggaaagac aatggaagaa
     5041 ttagcagaaa aaatcgattt accaaaagaa acactagcaa aaacagttga tggatggaat
     5101 acggatgttg cggagaaaaa agatgctcaa ttcaaccgtg ccacagccat ggaacatgac
     5161 ttatcgtctc cgaattatta tgcgatcaaa atcgcaccag gaatccatta cacgatgggc
     5221 ggtgtgaaaa tcaatacgaa cactgaagta ttagataaag aaaaccagcc aattaggggg
     5281 ttatatgctg ctggtgaagt cacaggtggc ttacatggaa acaaccggat cggtggaaat
     5341 tcagttgcgg agatcattat ttttgggcga caagcgggca tacaagcagc tcgatttgct
     5401 tcggaaaatg aatgaaatag aacgtaaata aaaagaggtt gtgaaatcag cgttttgagc
     5461 taataccgag ggtcagctga ttgaacactg tttagtgaag aggttgtgaa aaagctgccc
     5521 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggttgg
     5581 acttattacc gcagatgcaa gcttttgaac accgtttatt cggaaaaaga gcgtgggaca
     5641 aaagtaaaga acacttttgt ctcacgctct aaacacgtat aaacggcgga agcagaagaa
     5701 attccttcgg aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaatttct
     5761 tcttatttct tggagttaaa cgcttctgtc ccagcctctt ttttgatcag catgatttta
     5821 ttcagttatc ttcaaaatga tttttccgat gtttttgttt gcttccatat attcatgcgc
     5881 ttgtttgact gcgctgaatt ggaatgtacg gtcaatgatt ggccgaatct tgccattttc
     5941 tagaaaaggc ccagcttttt gcataaaagt ttgtgcgagc tctgctttat actgatcact
     6001 tctaggtgtc aataatgtac caagcagttg gacacgtttc ccaatcaata caccaaggtc
     6061 tatctcaggc acgatggtcc cacctagcat accaatcaag acccaacgtc catcaacggc
     6121 tatagaagct aaattctttt cccagtaaga agcgccgatg aaatccaaaa taacatcgac
     6181 tccccgacct tcagtgattt ttcgtacctc ttcttgaaag tcttgttttt tatagttgat
     6241 caattcatct gcaccaagtt ctttacaaaa ggcgagtttt tcttctgatc ctgcagtaac
     6301 gatgattttc gcgtgagaaa gctgtctagc taattggatc gctgctgttc ccacaccact
     6361 tgctcctgca tggatcaaga cagtttcgcc ttcttgtaat tttccaagcc agtaaagtgt
     6421 ttgataagca gtcaaaaaaa cttctgagat tccagcagca gaaacatagt ctagcgtatc
     6481 agggagaagg attgcacgat cggcaggcat cacagcatat tcggcataac cacctagatt
     6541 gactaatccg tatacttttg tcccaggagt aaaagtggag atatcacttt tattctcaac
     6601 tacctctcca gctacttcga ctcccaaaat agggtaggga ggtttcaaag agactgattc
     6661 tcttttcata atatctgttc gattgacagc tgctgtatgg actttgatca gtaattcgcc
     6721 ttgttttggt ttaggaacag gcacttcaat ttgttctaat acatctacag aaccaggatg
     6781 cttgattgaa atggcacgca tggatctatt cctcctttgc ccattcttgg aatgctgtat
     6841 tcaactcttt gctaccttca gaaagtacta gagtcgtacg agaaatatcc gtttcttcca
     6901 ctagagcggc aagtacagca gcaactgtag agcgagtgat cgtttttgat gccttctcat
     6961 taggcttagt taattgaatg gaagtaactt cttcatcgtt agtcaatgtg actggttgaa
     7021 gaatgacaaa atctaagtta gttcgtttca gccattcatc tgcataatgt ttagtaatat
     7081 aataatctgt catggactca ggccattttg ctggttcatc tgcataaaca gcactgacca
     7141 tcagatagcg agagacatgc gcattttcag ctgcgatcac tgttttgatt gcgccatcca
     7201 agtctacttg cagaagattc tttccttgag agccggcagc aaaaatcaat acatcgatgc
     7261 ctttgaatgc ttcggtcatt ttttccacgg accaagttaa atcaaaagag acatacgaaa
     7321 cattctcttt ttttactaat gtttgggaag caacatctct cacccctgca aaaatttcat
     7381 gggaacttgg agctaaatct tttatcaggt gtcggccaat ttgtccgttt gcacctacaa
     7441 caaaaatttt catttggatc atcctttcga cgtcaaatct ttccattcaa tagtaacacc
     7501 aaaagagaaa aaaatcagag atcggctacg atgactatca gttagtaaga gaagggtgct
     7561 tgaagtatct taacaagaca ttgcatactg ctgcagtcgc aagacctgcg acgattcctt
     7621 caggtatacc acttgtaaaa ataaccgcta gaatagctga ataaacagca tttaaatttg
     7681 ttccgatgac tttggcataa tcttgctgga ataaaaagta gatcatattc atcactaaaa
     7741 tcgtattggt caatgaaccg gaaagtccag ctaagaataa agaaacggaa tctgcttttt
     7801 gtttcattag tttgcgcaga cctttataaa cgaaataagg aaccacccca atcaagatgc
     7861 gaggaataaa cgcgatcagc aaggctttcc agcttccatg ttctgttccg atgactggga
     7921 taaacggaga aaagacaaaa gacaaaggtg tttggataac tgtgctacgg atcatgctga
     7981 tcagtccaaa tgtaccgcca agaaaagcac ctagtcttgg tcctaaaacg atcgaagcaa
     8041 tgattacagg aatatgcatg gttgttgcat tgattggacc gatagggata aaacctaaag
     8101 gcgtaacagc taataaaatc aaaatagcta aaaacatcgc agttaatgta aagttttttg
     8161 tatttttcat aagtactcct tttttctaag catttctttc attaagagtc agcatgacct
     8221 gttcgatgat cgtctgaata tcagctaagg caccttttcc aaaatctcca caagctaaaa
     8281 gagattctct tggttcaatt tcctgatagc cgacagatct caatgtttcc agattacgct
     8341 gagtgatcgg gttttgatac atattcgtgt tcatggcagg ggcaatcaat tttggtgttc
     8401 ccactggaag cgccattgcg actgttgaaa gaagatcgtc tgcaatgccg tttgctagct
     8461 tgccgataat gtttgctgta gcaggcgcga tgagaaacaa gtcagcttgt tttgctagtt
     8521 cgatatgatt gattacctgc ggatttgatt cttgcatgac gtctgtatgg actgcgcgct
     8581 tcgacagaga ttgcaaggtt aatggcgtga taaaatgtgt gctgctttta gacataatca
     8641 catctacctg ggcacctaat ttgacgaatt gacttgtaag atcagcgctt ttgtaagcag
     8701 aaatacttcc agtaacgcct agtaagatct ttttcatttt gattcctcca gtctaatttt
     8761 ctcagtaatc aatgcagcaa tctcagattt actttgagct tcttccactg ttccatcttt
     8821 agataagaga tagccgtggt gtgtctcgcc atggatttcc gtcaaatcat ttgcgaaaat
     8881 aaaatcagtt ttgttattta tcagactatt ttttgcgact gccagaagag attcctttgg
     8941 tacatctact aatagtttga aaccaatgat ttttgctttt ggctgccatt cacgtagata
     9001 agaaatgatt tttggtgttt tcttcaaaac gagcacaaga tgctcggtgt tagaagagat
     9061 ctttgaaaca gtggtatctg tctgttcatt ttccgcaaac caattgtcca gttcttcttg
     9121 cgttgaagaa gtgggtaggt tttttgccag ctgttcttct gaaaaactaa aagcaggagt
     9181 aaaatcactg actgccatac tgtggataat cgcatcgtag tgttcttttt tcgttagttc
     9241 ttctaattgt aaaaataagt ccagtgcaga ttcgatcgta taaatcgtta tattggagtg
     9301 tcttttcggt ttcagtgctt gtttcgtagt cacgtaatcg attgtggtat ccggattggc
     9361 agctaaataa tcagctaatg cttgccctaa tcgtcctgtc gaatgatttg taatagcacg
     9421 tacttgatcg attttttcag tcgttcctcc agctgtgatt agaatcttca tttatggtca
     9481 cctacattta ctagtgttct tccttggtgt gttccagcaa gtagtttaga tgctgtttca
     9541 ggcaattgat ccagagtaat ctcttggacg accagttcat ctgcaatctg caaatccgcc
     9601 atctgttgcc ataaagaaag acgttgatct attggtacat tgacagaatc aattccaatc
     9661 aactggatgt ttcgcagaat aaaaggcaag acagtcgcgt ttagtttgat tcccccagca
     9721 ttgccacata aagctactgc accgttataa gagatcaatg gaagaagact gcttagctgc
     9781 tcgccaccta ctgtgtcgat gacatagtcg atttgctgtt ttcctaaagc ttttgttgtc
     9841 tctggcagaa attcatcagg tcgtacgact tgcaaagcac ctagactttt tagccatgtg
     9901 acagactctt cttttctgga aaaggcaatg attgactgga atcctagttt atgtaacagg
     9961 gctatcgctg tactgcctac accgccagaa gcaccagtaa cgacaacttt tttatcggag
    10021 gtcatacctt gacggattaa agcgttcaca cacaacatag cagtaaaccc tgctgtacca
    10081 aggatcatcg cttgacgcag cgtcatattt tttggtagag gaactaacca gtctcctggt
    10141 actttttgat attggctata accgcctgga tgggtgacgc caagcccaaa accagtagca
    10201 agtacaagat cttcttttga aaaacgtgga ttgttacttt ggacgacagt tccggataaa
    10261 tcaatccctg gagtcatcgg atatgttcgt atcacctgac cagactcgct cattgccaat
    10321 gcatctttat aattgacatc agaataggca atttttacca agacttcatt ttcagccaac
    10381 tcagtaaatg gcagatcact gattgctgta tggaaaacag gttcctttat tacctgaaaa
    10441 gatcgaaaag cgttcattcg tgagacactc cttttaaaat tttcttttat cataccataa
    10501 agcctactct tttattcttg ttcttccgta aatttagaca aaaattaggt gaaaaataaa
    10561 gaatcaaaca actagaattt attccaaaag ataaagaaat attcagcaaa aaaaatttta
    10621 caaagggttg cctttttcaa taaatttcgt atactaatac gagtggtagt aaacaggaag
    10681 tttactatta gaaaacttcg attcggagga aattatggaa attggtgaga agttaagaaa
    10741 tttgcgcatc caaaagaatt tgacacaaga agaactaggc gaacgcacag atttgtcaaa
    10801 agggtatatt tcccagttgg aacgagattt aagttcacca tcaatggaaa cattcttttc
    10861 tattcttgaa gtcttaggtg tgactccaga agaatttttt catcaagaag cagcgaatct
    10921 gcaagtggtt tattcaaaag aagatcatac ggtttatttc gatgaagaaa acgggtatga
    10981 attggaatgg ctcgtggctg attcgaatga aaaagaaatg gagcctgtct tgctgacttt
    11041 tgaaggtgca ggagaatata agacgtttga accttcatta tctgaaacgt ttatttttgt
    11101 attagaaggg gaattagagt taagcttagg agagacggtc tatgtggcaa aagcaggaca
    11161 gtcgatctat tatcaagcga caaaacaaca tcaattaagg aatcatctca aaaaacgaac
    11221 aaaagtattg attgttgcaa cgcaatcata tttgtaatat agggggtaaa aacgtgggga
    11281 aaccaatcat ttcatttgat caagtagtga aacgctatga tgatgaaaca gtattaaaaa
    11341 aagtaagttt tgagatcgaa caaggaaaat tttatacact gcttggtcct tccggctgtg
    11401 gtaaaacaac gatcctacgt attatagctg gattcaccga agctacagaa ggggacatct
    11461 attttgaagg gaaacggttg aatgatttgc cagctaataa gcgacaagta aatacagtct
    11521 tccaagatta tgcacttttt cctcatatga atgtttttga taacgttgct tttggattga
    11581 agatcaagaa aatgtccaaa tcagatatcg aaaagaaggt aaaagatgct ttgcgtatgg
    11641 tccagcttcc tggatacgaa aaacgggaga ttagtgaaat gtctggtggt caaagacagc
    11701 gtgtagcgat tgcacgagca attgtaaatg aaccgaaagt attgctatta gatgaaccgt
    11761 tatcggcgct tgatttgaaa ctacgtacag atatgcagta tgaactgcgg gatctgcaac
    11821 aacgattagg aatcacgttt atttttgtta ctcatgacca agaagaagcg ttggcaatga
    11881 gtgatgagat ttttgtcatg aataaaggga aaatcgtcca aagtggtaca cccgtagata
    11941 tttatgatga gccaatcaat catttcgttg ctgattttgt tggggagagc aatatcgtgg
    12001 acggtgtaat gatcgaagat aatctagttg agtttgttgg taagcaattt gaatgtgtcg
    12061 atggcgggat gcgtctaaat gaaccagttg aagttgtttt acgcccagag gatttgacga
    12121 tcacgacacc agataaagga aaactagtcg taacggtcga tactcagctg tttcgtggtg
    12181 tccattatga aatcatctgt tatgatgaac agcaaaatga atggatggtc cattcaacga
    12241 aaaaagctaa agaaggaagc aaagtaggat tggcctttga gccagaagat atccatgtca
    12301 tgcgtttcaa cgagtctgaa gaagaattcg atgcacgtct tgacagctac gaagaatagg
    12361 ggggacaaga atgaaaacaa tgcgcaggat ctattccgtc ccttatattt tgtggctcgg
    12421 tttattcgtg atcgcgcctg tattaatgat catttatcaa tctttttttg atatgaatgg
    12481 gcaattcacg ctgaataatt atctatctta ttttacgtcg gggacatcgc tttctatgac
    12541 gatcaattct gtatggtatg catttttgat cacgtttttc acgctgatca tcagttaccc
    12601 gactgcttat tttttaacaa aactgaagca caagcaatta tggctgatgc tgattatttt
    12661 gcctacatgg gtgaatctgc tgcttaaagc ttacgcattt attgggattt tcagtgtgca
    12721 cggcagcgtg aatcatttct ttgattttat cgggatcggg ccgaaacaga tattattcac
    12781 agacttcagt tttctgttcg tggcaacgta tatcgagatt ccatttatga ttatgccaat
    12841 tttcaatgca ttggaagaga tgaatccttc tttgatcagt gctagtagag atttaggcgc
    12901 gaatagcttt gagaccttcc gacgagtgat ttttccgtta tcattaaatg gtgtgaaaag
    12961 tggtgtccaa gcagtattta ttccttctct ttctttattc atgctgactc gtctgattgg
    13021 cggaaatcgg gtgatcactt taggaacggc tatcgaacag catttcttgg ttacacaaaa
    13081 ctgggggatg ggttctacaa tcggtgtgat tttaatcatt gctatgttca tcgtgatgct
    13141 cctgacaggc gagaagaaaa aaggaggtcg ctcataaatg aaaaaattta aatggtcgta
    13201 tctttattta gggatcgtct ttttattcct atatgcaccg atcttctatc tgatttttta
    13261 ttccttcaat gaaggaggaa cgatgaacag ctttacagga tttacttggg aaaattatga
    13321 agctgttttt gaagatacac gtttgatcat tatcgtattg aatacgttca tgctggcttt
    13381 cttatctgca ttgatcgcca cgatcatcgg gacatttggg gctatgggaa tctattacac
    13441 gaaaaaacga cgtgcacgga cagcgttgtt gagcatgaat aacatcttat tagtctctcc
    13501 tgatgttatt atcggtgcta gtttcttgat tttctttaca ctactaggat tcggattagg
    13561 ttttcagagt gtattgcttt cccatattgc tttcagcatt ccaatcgtcg tcttgatggt
    13621 cttgccaaaa ttgcaggaaa tgaacgattc aatggtcgat gcggctagag accttggtgc
    13681 taataatttc caagtagtca aaaatatcat tttgccttat ctttctccag gaatcatagc
    13741 tggatatttt atggcattta cctattctct tgatgatttt gcggttacat ttttcgtcac
    13801 aggaaatggc tttacgacgc tctcagtaga gatctattct cgtgcaagac aaggaatcag
    13861 tttagaaatc aatgcgctaa gtgcgttagt tttcttgttc tccatgatat tggtcattgg
    13921 atactacttt attagtaaag aaaaccgtcc aaaacggctg aagaaaaaca gaagagtacg
    13981 cgagggggtg gcacggctgc gatgaaaaaa ttacaatctc tgtttttagg tattctcatc
    14041 attattgcgg tgctgctgct tggtgttcgt caacttgaaa aaacaagtgg catgagtgga
    14101 gcaaaggtac ttaccatcta taactgggga gattatatcg atcctagttt gatcacgaaa
    14161 tttgaaaaag aatatggata caaagtgaat tatgaaacat ttgattctaa tgaagcgatg
    14221 ttcacaaaaa tccagcaagg tgggacaaac tacgacatcg ctataccaag tgaatatatg
    14281 atccaaaaaa tgatcaaaga aaaactagta cttccattag atcattcgaa gatcaaagga
    14341 ttaaataata ttgatccacg atttttagac ttggattttg atccagataa tcagtattcg
    14401 attccatatt tttggggaac tttagggatc gtatataacg ataaattctt tgatgcaaat
    14461 caaattaagc attgggatga tttgtggaag ccggaattaa aagacagttt gatgctgatt
    14521 gacggtgcac gagaagttat ggggctttct ttgaatagtt taggctattc tttgaatagt
    14581 aagaatatgg cacagctgac agaagcagca aataaattga atcatttaac accaaatgtc
    14641 aaagcaatcg tggcagatga gatcaaaatg tatatgatca atgaagaagc ctccgtggca
    14701 gtgacatttt ctggcgaagc tgccgatatg atgtgggaaa atgaacattt acattatgtg
    14761 atcccaccag aaggatccaa tctttggttt gataatatcg ttatgccaaa aaccgtgaaa
    14821 aataaagaag gtgcctatga tttcatcaac tttatgctag aaccggaaaa tgcggcacaa
    14881 aatgcagagt atattggtta ttctacacca aatgaagaag caaaagcgtt attgccaaaa
    14941 gacatttcgt cggacgaaca attctatcca tctgatgaca cgatctccca tcttgaagtc
    15001 tacaaagatc taggatcgaa atacctaggc atctataatg acctattctt agaattcaag
    15061 atgtatagga gataatggca aaactcagta agaatgggga cttatcaacg ttctaaagag
    15121 ctaaaaatcg tcctttttct atctgagttt tccaatcttc taccaaaagc ggatgaaacg
    15181 ccgctttttt tgtgttattt tattttttct accacgtttt tctaccagag aaaagtggac
    15241 aaaaccattg taaaataggg cccgagacgg gctagtaaat ctaagattga aaaagttaca
    15301 gaaggataaa gtaattggaa actatgcaaa tatacttaac ccttctgtaa tctattaata
    15361 aaactaatat atgaatccag ttcaatattt gtagctatga aaaaacataa aaatcatatt
    15421 agataaaaac taaattggta gataaattat tttgtcagat atctgaggca aatattcgac
    15481 tatttgtgtt tcaaagtaaa aattggaata caaatataga atagacatat tgcagccgat
    15541 agtttattat gcttttagac acattaaact ggaggaaaaa atgaaaaaga gcgctaaaga
    15601 tcgagttttt gatgagctga tacgactaac agggaatatg tcttctgtca ctgccgagaa
    15661 aatttcgaag aatctaggta tctctcgtca gaatgccagc cattatttga cgagattagt
    15721 ggaagataaa aaggtcgaga aattaccggg aaagcctgtt ttgtggaagc ctttagatga
    15781 atatgcggtt gtagataata cggagcaaat aaacgaagcc tttcattctg tagttggtca
    15841 tgacggaagt ctgagagagg tcattcaaaa atgtatagcc gctgtcaaat atccgcctaa
    15901 cggactcagt gtattaataa atggagccac gggtgttgga aaaagttttt tagccacaaa
    15961 aatttttgaa tacgctatcc atgagcaaat tattgaaaaa gatgcaccat ttgctatctt
    16021 aaactgtgcc gattatgcgg acaatcccga actgctttcg gcaacactgt ttggatacaa
    16081 gaagggggcc tttacggggg ctgaaaagga taccgatggt ttattggcaa cggccaacaa
    16141 cggctatctt tttctcgatg aggtccatcg cctatcgaaa gaaaatcaag aaaagctctt
    16201 tctatttatt gatactggaa actatcgtcc agtcggtgaa aatgtaaatt ggcattctgc
    16261 taaggttcgt tttattttcg ccacgacgga aaaaggtgaa aattatttat tagacacctt
    16321 tgatcggcgt attcaaatta gtgttatgtt gccaactttt gaagatcgcc ccattcgaga
    16381 acgattagag ctgattcaat tattttttca aaatgaagcg gatgttttac aaaaagatat
    16441 tattgtttca agagaagcct tgtctttaat gttatctcat ccctttagtg ggaatattgg
    16501 taagctgaag aatatcatta aaatcagttg tgcggatgtg tatagtcgaa cacaagaaga
    16561 accattaacg attgggaaaa atgagatctt gattcagtta aatatgctgg aatccgaagt
    16621 agaaagcttg ccgattgcta gtttattgat aaagaaaaat caaaagataa aaacggatcg
    16681 aatcaaaccg tttgattatg attcgatttt ggaaaaaatt actcagctga taaatgaagg
    16741 taatttcaat gaaaattttt cttcgataaa gaatgaagta cagcatttgg tgcatcacat
    16801 tgataaggat tcttttttat caatgagtag aaaattgatg attcagatgt ttagaaaggt
    16861 ctgggtatcc gttttaggaa aaacgtacgg attgacgacg agtggacctg ttgcagaaat
    16921 tattagcaga tcctatgtca tttccccaag ctataagaca gacttaaccg ggataaatcg
    16981 tacattagct gcaaatctac ctcggacgac ttacttatgt aatcagttct tggagcattt
    17041 accaccgctc tcagaaaagg acgagaactt tctaagactg cttattgtcg tgactttatc
    17101 tgattatgta gatgaatcca tcgagctgaa gggcctgttg cttgctcacg gagatagtac
    17161 ggctagcagc attcaagcag tagtgaatca attatgcggc aattatgttt ttgaagcgtt
    17221 ggatatgcca gtagagagta atgtgtcaga gattgtcgaa tcgacaagga atttcgtgaa
    17281 acggcaagtg aatacagata gtctagtgct gatcgtagat atgggctctt taaatcaaat
    17341 ttacacacag atcaagaacg atttaaaagg ggagttactt cttctgaata atttgacgac
    17401 ttccattgca cttgatattg gcttgaagat gacgatgaat gcgccattta aatagattgc
    17461 ggaggatgca gcagacaagt attcaatcaa tgttcaatac tttgaaggct tttctcaaag
    17521 tagcaacatt atcatttcct gtatgtcggg tttggggatt tcggacaaat tgaaagatgt
    17581 ttttcgtcat catttatcgg atgaatccat cgaagttttc acgaaggact acagagaact
    17641 acgtgaatta atcgaccaaa atgatgaaac ttattttgac aagacaaaat tggtcatcac
    17701 gacttcggat cttccacgtt ccttttcaat tcctaatatt aatgtttatg acatcttaga
    17761 cggtgatgga gcagccaatt tggagcatat tttgagtcct gaaatgaagc cggcagaatt
    17821 taaccgcttg attcaggagc tagtaaaatt cttttcgttg gaaggaattg cggaccgttt
    17881 gaactttctg aacccaacga tcgtgatgag tgaagtggaa acagtcattt ctaaatatga
    17941 aaattactat catttcactt taaatggccg tgtaaaacta aatctctata tgcatacggc
    18001 attgatgatg gaacgtttat tcttggctcg gacagaaaaa tctgaagaac cgaattatga
    18061 tttgaaacca gatgaagatg aattttatta tgtttctaga agtatttttc aatcaatgga
    18121 gatgaaatat aattttaaag tcaatgctta tgagctttcg ctgctctatg aattattagg
    18181 accgtatatt caaaaataaa gtgtctaaaa aagtgtctaa tctgtttttt ttaggttaga
    18241 cacttttttt aatgtgaatt aacgtgatta aaccaatgtt tttaaaagtt ggcacaggaa
    18301 ttgcttatat aaaagtgaac agaaagaaag gaattaacca tatgaagaaa attctaatag
    18361 cgactcacgg tcacttagct tcaggctttc ttagcagtat tcaattactg acggggaagg
    18421 ttcaagagat tacggtgatt aatgcttatg tggatgagtg tgattttgaa caggagttga
    18481 atgtatttgt aaaccaggtg aacgagcagg atcagatttt tgtttttacc gatttatttg
    18541 gcggaagtgt caatcagaag attaccaaaa cctttttgga gaaagagatt gctgtaacta
    18601 ttttgtctgg ctttaatctg ccaattctgc tcgaaatagt attggcaacc aaggaattaa
    18661 caaaggagga tattcaggaa ctggtaaata aatgccaaca ggaattaaag atgaccattc
    18721 ttgatgaggt acatgtagta aatgaagagg aagatttttt ttaggaggaa gaaaaatgat
    18781 taaagcagtg cgaattgatg aacgattaat tcatggacaa gtagcgatga cttggacaaa
    18841 gagtctaaat ttaaccgggt tagtagtagc aagcgatgag gcggctacca acgatattca
    18901 aaagatgaca ttgaagatgg ctgcaccatc gaatgtcaaa gtcattatta aaacagttga
    18961 tgacgcgatt catttgttaa aagatccgcg ggcgaaggac atgcgcttga tggttttagt
    19021 ccctaatgtc aaagatgcgg taaaagttgc gaaagctttc ccaacggaaa tcgaattaat
    19081 gaacgtgggg aatgctggga aaatgacacc gccatcggaa gataagaaaa ccttatcaaa
    19141 ggaagtgatg ttaacgacgt cagaaattca agacttaaaa gaattagttg aactttatcc
    19201 agataccgtt tttcagccta caccggcgat ggaaaaacgt tcagctatct ctattttgag
    19261 tgatttttag aaaaaggaag gagaaaaatt atgtatgatg catttgtagt cgctttggcc
    19321 gtttttattg gagttgctgg acatgaaatg ttcgggatgt ccatgctgag tcgtccgatt
    19381 gttgttgctc cgttagcagg agcgttgatg ggggatttgc agacggggtt gattgtcggg
    19441 gcgtcactag aagccatctt tatgggtgtc gtcaatatcg gaatctctag tacggcggag
    19501 ccttctttgg ctgctgggct ggctacagcg ttcgcaatca aaatgggagg aaacgtggat
    19561 gcgattattc ccattgtctt tccactagca gtattaggat tacagttaat gaatatgatt
    19621 ttttcttttg tatgtggacc gatggctgct aaatttttca aatttgcaaa atctggtgat
    19681 caaaaaggaa tcatcaatct gcacttcttt atgtggtttg tccactatgc gctttatgct
    19741 cttattccat tctttgccgt tttatttgga gcagatgttg tcaaaagcgt cttggataat
    19801 attccagagg tcatcatgaa cggattaaca gtcgctggaa atctgctgcc ggcagttggg
    19861 atggcgatgc tgttacggat gctttggagt aaaaatattg ctgtgtggtt tttctttggg
    19921 gccgttgtta tggcgtatct cgagttacca ttgattgcaa ttgccgcagt tggaacgatt
    19981 attgcaattg ttatagccca aagagatcta caactaaaaa atatatctgt tcatgcagtt
    20041 caaagcgatg ctgctgtaaa tgcaacgctt gaccaagaag aggaggattt ctttcaatga
    20101 aattagctga tggaatttct aaagatgaga aaaaattggt tcggaagatg ttttggcgct
    20161 cgatgactat gtatgcttcg gtgaatccgg tgacgatggg cggcggtggt ttcgcctatt
    20221 ctatgatgcc cttcattaat catttctaca aaagtgaaga agatcgagct gcggcgctgg
    20281 aacgtcatac acagtatttt tcgacgacca ttccttgcgc gtcctttgtc atggggattg
    20341 cggcatcgat ggagaaggaa aattctgaaa aagctggttt tgacgtggaa agtatcaacg
    20401 cgatcaaaac gagtttgatg ggaccattgg ctggaattgg cgattcattg ttctggggag
    20461 tttggcgtgt cgttaccgcg ggactagcga tcaacttagc caatgccgga aatattttgg
    20521 caccaattat ctttttagtt atgttcaata tacctaatta cttgatgcga tactatggcg
    20581 gcgttttagg ctattcatta ggctctaaat atattgaaaa gctgtatgcg aacgggttaa
    20641 ttgaaattct gacaaaagct gctagtatct tgggtctgat catggtaggt gcaatgacga
    20701 tcagtatggt caaattcaat accgttttga gcttttcaat gaagggcgaa gaactaatga
    20761 atgtccaaga aatcctcgat agtattttta aaggaattgt accgttattg gtaacattga
    20821 gctgtttcaa attactagat aaaaaagtcg gcgtcatcaa aattattttt ggaatggtcg
    20881 tcttgggaat tttattgtca ttacttggaa tcgcatagta ggaagctgca gctactaggc
    20941 tgcagttttt ttagcaagga gggaaaagat gactattaat gaagtaattt attcacccaa
    21001 acacccattt tttaatgctg agttaaacga cggaaatgtg actacttcaa acgaatacag
    21061 ctactatcgg aatattcctg atgtaaaggg attgaccttc gatgtaagta atcaaaagac
    21121 attagcaaac cttgatgttt gcgggacgat tcaaacgttg accttttatc gagaaaattt
    21181 actaactgag gaaaaaccag gtgtttgggt caataaacag ctctctcaaa ccaattcgtt
    21241 atccttaaag gttgaagtaa acgggattgt ctaccatttg tcagaatcgg atcatcgtat
    21301 tgaagtcgat gtgattcaag actgtttgcc tagatatatt catcattatt cgacgtttaa
    21361 ggtcattgta gtatcctttg ctcccatact ggctaataag cgtttaagta tgcttgttca
    21421 acaggtttac attgtgaatg aaacacacga aagccttcaa gtttcagtga aagatgtgcc
    21481 ttcgtatcaa gagaagtatt cggatcagca aaatgtgttg atttctcaaa aaggaaataa
    21541 ggacacgatc gcacaacagg aagtggcaag cttcgccatt gcttttgtgg acccaaatgc
    21601 ttttgaagaa gtaatgactt ttcaggaatc tgatatcgaa aaatggctga aggaaacatt
    21661 gaactatttt gctcagctat ttgggcagct gtcaatgcca aacgatagag ttgtccatct
    21721 ctatcgtcgt gcactttatc aaagcttttc tagtttcggt atgaatcgac agggacaggt
    21781 cgtcggcagc aattggggca gctatcctgc tactaatcga atttggaata aggatatgta
    21841 ttacgcatca ttgccattca ccatgtttga accggagtta tgtcaaaaaa cggttctatg
    21901 gtttgatcaa tatggcgtta agtttcctgg ttcaaaattt acaggaggta tcaatcattc
    21961 tctgagtaat tcgttatcca gtgcgttact ggctagtctt tattttgaac atactgggga
    22021 tacaaaattc tttgagcggt gtccgcaggt tctactgaat gcttcaagaa ttattgagga
    22081 catattagct caacgtcggt caggggaacc aatgcttttt ccatctgttt ggttatcaga
    22141 cgcctttgca cttggaaagt atcataccgg cagcaatctt tgtctttgga aggcctgtat
    22201 tggacttgca gaaatttttg aagccctaga acaactgagt cttagcaagc gatacaaaaa
    22261 cattgcctgt aaactaaagg aatcaatttg taaacaaatg actatcgatg gtccttttgg
    22321 tgagcaattt ttggagggaa tcggtgatga ggagaaaaca acctattcag tgaagcacta
    22381 tcaaaaaccg attcttgagc aagggttaat ctttttaagt gatgtgattg tggatggaaa
    22441 aattaattta ttgatgcatg atggagaaga atcagacact acgttgatgc ctttttatca
    22501 atttttagat aataaagatc atttatatca gaacaccatg gccttttctg ctagttcttt
    22561 caatccaacc tatagcgagg aaatcaaagg catcacttgg ggattagaat ccggcgccac
    22621 ttttcctggc tttatcactg ttttaatgag cgagctgcac aaccctcaag ctttcgtaac
    22681 ccgattagaa gaactaattt gtttggcaga tttagacggt tcgtggtggt ggtggccgta
    22741 tcgcttagag gctcaacaag gagaagtcgt gcgagacttt ggctgcggca aatgcggctg
    22801 ggcatcgggt ctttttgtca gcctaatgat cagtcaatat ttcggattga aattcaaaaa
    22861 aggagtattg caaattgatc ctgttgataa tttaacgttt tcttggaaga atttgaagtt
    22921 cggtcaagcc ttcatttcga ttgaatgtac gcaatccgag ttgagtattt caaatttgtc
    22981 agaaaagcca ttgaaaataa gtgatacgaa aaaaattctt cacgtagaaa agggaaaaac
    23041 gattcacatt caaaggagaa aaagatgagt atactaaaaa atattaccca atttaaaaaa
    23101 atccagagtc gagcaatcac tcccgaaaat ccaacaggcg agaaaggtaa agctgcgatg
    23161 ttgccaagcg agctaggacc aagccgcaaa ggtcgtggcg caattccgct gacttctggt
    23221 gaagaaactg tgattgcgga tattactgga acgggaataa ttcgtcatat gtggatgacg
    23281 attcgtgatc gaacagaatt tggcagtttt gttttacgtg atttaatctt aagaatttat
    23341 tgggatgggt cggatagccc tgctgttgaa agtcctttag gggatttctt ttgtaatggg
    23401 tttggagagc gttgcgaggt gaactcgttg ccgatagtgg ttaatcctac agggggcttt
    23461 aattcctatt tcgaaatgcc tttccaaaca tccgctaaaa ttacgatcga gaatttacat
    23521 ccgaaggata tgtcctcatt tttttatacg ataaattacg ctttggtgga cgaattggaa
    23581 gaaaatagcc tatattttca cgcaaattgg catcgggaac gcattaccaa attacaggag
    23641 gattataagt taattgatcg attaaagggt caaggctatt acgtgggtac ttaccttgcg
    23701 cttacctgcc tagaacgtta ttggtggggc gaaggcgagt ttaaattcta cattgatggg
    23761 gatagtgagt atccgaccgt aacctcaaca ggttcagaag attattttgg cggggcgtgg
    23821 gcctttcatg agtacgatga gttcggacgt ccacatgcga aaaactattc aacagccttt
    23881 ttagggtatc cttaccaatc aaatagagat gccacaagag atcgttttga aacgggaaaa
    23941 ttgaatgccg ttcatgcctt tggtgacgac gcaatgccac gacatggtct ttatcgttgg
    24001 catcttcaag accccatctg ttttaccgaa gatttatcgg tcactttaca acaaatcggc
    24061 aacgatgatg ttcgcttatt tgagcggcaa gacgatgttg ctagtgtcgc ttactggtat
    24121 tcaacagaag cttcaggaaa tactaaacgt catttcactg atcgagaacg cttgccgcgt
    24181 taatgaagtg tttttcacat attcgaaggg aggaacctat gatgatatat ggggcaattg
    24241 aagctggagg gactaaattt gtctgtgcag tcggtactga ggaattaacg attttggaaa
    24301 gagtcagttt tcccacaaca actccagttg aaacaatgaa gcaggtcatt gattttttta
    24361 aaccttttaa ggaacaattg gcaggcatcg gggtcggctg ctttggtcca attgatattc
    24421 aatgcaaatc aacgagtttc ggtcatatca catcaacacc aaaacttgct tggcaaaatt
    24481 tcaattttgt aggaacgcta aagcaatatt tcaatattcc gattgaatgg acaacagatg
    24541 tcaatgcggc ttgctatggt gaatatgttg ctggttctgg caaagggtta gcaggtgttg
    24601 catacttcac tgtgggaaca ggtatcggag gtggtgcctt gttcaatggg actttcgtgg
    24661 aagggttcag tcatccggaa atggggcata tgttgatcaa gcgacatcca aaggacaatt
    24721 tttcaggaaa ctgtcccttc caccaagatt gtttagaggg gatggcagca ggaccagcga
    24781 ttgaaaaacg gttgggtgta aaaggccaga atttattggc tgacgattcg ttttggcaga
    24841 ttgaagcctt ttaccttgcc caatgtgcat acaatacaac actgatgttt tcgccagata
    24901 gaattatttt tggcggtggt gtaatgaaac aagaacacat gaagaaaaaa gttcaggata
    24961 aatttgttga gcttataaat ggatatgttg aaataccacc aattgatagc tacattatta
    25021 cgcccgaatt aggtgataat gccggaataa tcggcggatt agcattggcc agaaaagcgg
    25081 taagaaataa gcaaccataa ttaatgaatg tttcattgat actcatgtca aaagtattta
    25141 accgagtaat caaatgatca aatgaagttg gataaagcga aaatgaattc aaataaaaag
    25201 gctctaagtc aaatcgtgtt gttttcatta aatcactgaa aggaaatgct tctgcgtttc
    25261 cttttttctt tttgttgtgc gctgtatacc ttgaggatat tcactggtgg cgtacactta
    25321 aatagtaata tattgtgtta ctttatgtct gtggtaatag ttatagttgc ttaccaatgt
    25381 atgttcattt ttcgaaatgt tgacttcata atccttggct taatgtttga atttttttgg
    25441 tgatagattt tttcagccgt ataaaataaa tcgtaattct attatagaga gttgtgatta
    25501 taaaaagata gcaagaaaaa aaaagaaagt ttctatacat tttaaatatt ttattcctat
    25561 ttctattgct aaaaaagtag aaattctata tttaccttta actctcgctt ctcttgcaaa
    25621 tgtagttagc at
//
LOCUS       DAZAOD010000029        24451 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000029 DAZAOD010000000
VERSION     DAZAOD010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.030"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..830)
                     /locus_tag="ACHDPO_001254"
     CDS             complement(<1..830)
                     /locus_tag="ACHDPO_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFN3368893.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     "
     gene            complement(1054..2994)
                     /gene="thrS"
                     /locus_tag="ACHDPO_001255"
     CDS             complement(1054..2994)
                     /gene="thrS"
                     /locus_tag="ACHDPO_001255"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFN3368894.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3331..3510)
                     /locus_tag="ACHDPO_001256"
     CDS             complement(3331..3510)
                     /locus_tag="ACHDPO_001256"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFN3368895.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3557..5380)
                     /locus_tag="ACHDPO_001257"
     CDS             complement(3557..5380)
                     /locus_tag="ACHDPO_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFN3368896.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5658..7937
                     /gene="helD"
                     /locus_tag="ACHDPO_001258"
     CDS             5658..7937
                     /gene="helD"
                     /locus_tag="ACHDPO_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFN3368897.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8030..8677)
                     /locus_tag="ACHDPO_001259"
     CDS             complement(8030..8677)
                     /locus_tag="ACHDPO_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368898.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8856..9575)
                     /locus_tag="ACHDPO_001260"
     CDS             complement(8856..9575)
                     /locus_tag="ACHDPO_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3368899.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9706..10857)
                     /locus_tag="ACHDPO_001261"
     CDS             complement(9706..10857)
                     /locus_tag="ACHDPO_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFN3368900.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11074..11814)
                     /locus_tag="ACHDPO_001262"
     CDS             complement(11074..11814)
                     /locus_tag="ACHDPO_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFN3368901.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11818..12141)
                     /gene="rsfS"
                     /locus_tag="ACHDPO_001263"
     CDS             complement(11818..12141)
                     /gene="rsfS"
                     /locus_tag="ACHDPO_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFN3368902.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12198..12791)
                     /gene="yqeK"
                     /locus_tag="ACHDPO_001264"
     CDS             complement(12198..12791)
                     /gene="yqeK"
                     /locus_tag="ACHDPO_001264"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFN3368903.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12775..13425)
                     /locus_tag="ACHDPO_001265"
     CDS             complement(12775..13425)
                     /locus_tag="ACHDPO_001265"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFN3368904.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13435..13746)
                     /gene="yhbY"
                     /locus_tag="ACHDPO_001266"
     CDS             complement(13435..13746)
                     /gene="yhbY"
                     /locus_tag="ACHDPO_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFN3368905.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13762..14871)
                     /gene="yqeH"
                     /locus_tag="ACHDPO_001267"
     CDS             complement(13762..14871)
                     /gene="yqeH"
                     /locus_tag="ACHDPO_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFN3368906.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14868..15395)
                     /locus_tag="ACHDPO_001268"
     CDS             complement(14868..15395)
                     /locus_tag="ACHDPO_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFN3368907.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15575..16360)
                     /locus_tag="ACHDPO_001269"
     CDS             complement(15575..16360)
                     /locus_tag="ACHDPO_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFN3368908.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16353..17222)
                     /gene="accD"
                     /locus_tag="ACHDPO_001270"
     CDS             complement(16353..17222)
                     /gene="accD"
                     /locus_tag="ACHDPO_001270"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFN3368909.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17223..18602)
                     /locus_tag="ACHDPO_001271"
     CDS             complement(17223..18602)
                     /locus_tag="ACHDPO_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFN3368910.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18610..19029)
                     /gene="fabZ"
                     /locus_tag="ACHDPO_001272"
     CDS             complement(18610..19029)
                     /gene="fabZ"
                     /locus_tag="ACHDPO_001272"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFN3368911.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19054..19530)
                     /gene="accB"
                     /locus_tag="ACHDPO_001273"
     CDS             complement(19054..19530)
                     /gene="accB"
                     /locus_tag="ACHDPO_001273"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFN3368912.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19533..20768)
                     /gene="fabF"
                     /locus_tag="ACHDPO_001274"
     CDS             complement(19533..20768)
                     /gene="fabF"
                     /locus_tag="ACHDPO_001274"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFN3368913.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20787..21524)
                     /gene="fabG"
                     /locus_tag="ACHDPO_001275"
     CDS             complement(20787..21524)
                     /gene="fabG"
                     /locus_tag="ACHDPO_001275"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFN3368914.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21536..22453)
                     /gene="fabD"
                     /locus_tag="ACHDPO_001276"
     CDS             complement(21536..22453)
                     /gene="fabD"
                     /locus_tag="ACHDPO_001276"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFN3368915.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22560..22784)
                     /locus_tag="ACHDPO_001277"
     CDS             complement(22560..22784)
                     /locus_tag="ACHDPO_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFN3368916.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22837..23799)
                     /locus_tag="ACHDPO_001278"
     CDS             complement(22837..23799)
                     /locus_tag="ACHDPO_001278"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFN3368917.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23809..24249)
                     /locus_tag="ACHDPO_001279"
     CDS             complement(23809..24249)
                     /locus_tag="ACHDPO_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFN3368918.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         6691 a         5441 c         4250 g         8069 t
ORIGIN      
        1 tattcttgga ttgcttctcg tgtttttttc actttttcgc taagcttttc gtttttagcc
       61 atatagaaat aaaaaatgat atcgatcgta gcaaattggg ccaaaagtga attagttgcc
      121 gcacttcgat tcgtgatttc ttttggtcta gatgtttgta cgagtacatc ggctatcttg
      181 ctaagcgggt tatttccaaa ttgcgtcaac gcaatgattt cgatattcat gcttttcgcc
      241 agctcggcta atgcgactac atctgcactt ctacctgagt ttgaaacaag ccaaagcact
      301 ttctttttct cattgctgac aagttgcggg agcaagacgt ggatatcttt ttcaaaaatg
      361 attggcttac cgacacgaga ccatttttgc agaatatctt ctactactaa agaagaggcg
      421 ccaaccccat ataaaaaaac agtctctgcc gattccaaac actctacgac tttttggatc
      481 gtttcttctt ctagaatatc tactgtttct tttatcgcta cttgtgcatt gttaccaagt
      541 ttgtttttga tagagtaaaa ggactcattt gcttctatat cactaaaacc ttcatcgatt
      601 ccagtctgta gttctgttga aatcgtgatt ttgaagtccg tcagactttg aaaaccgatt
      661 tttttggaaa aacgtacaac tgtcggcgca ctcaacccgg aagcttctgc taattcatta
      721 gctgtcattg tagggacctt ctcaatatta ccgataatgt agttggccaa ctttttttct
      781 gctgaagaat aatcttccat catactttca atacgactaa ttacgctcat aagttcctcc
      841 acccttttaa tgatagtcta tgtaagtata ccatatcaga cccttattca cggtcgtata
      901 ctggataaaa aacaaaaaaa caatccgccc aacagaatat cttatcccat caatcccaca
      961 gattctattg agcatctgtg tctttgagga atacctgtta tctattgttc ggattgcttt
     1021 ctatctacta cttttttaca ggaaatttac ctattagttt tctctgctgt aatttttgac
     1081 ttctgcttcc atagcatcaa taaagatatt caaatcttct acagctgttt ctttacttcc
     1141 ataacgacgt acgttcactg ttgcatcttc caattccttg tctccaacaa ctaattggta
     1201 agggatcttt tgtgtttgag aggcacgtat cttatagccc attttttcat tacgatcatc
     1261 aacttctaca cgcaacccct tcatttgcaa acgttctttg atttcataag cataatcgcc
     1321 atgtgcatca acagaaacag ggatgattgt tgcttgtata ggtgccaacc atgttggaaa
     1381 agcgcctttg tatacttctg ttaaataagc gacaaaacgt tccattgtag aaacaattcc
     1441 gcggtggata actactggac gatgcgtatt ttccccgtct tctccaacat atgtcaaatc
     1501 aaagcgctct ggcaataaga agtctaattg tatagttgat aatgtttctt ctgtaccaag
     1561 agctgttttg acttgaacat ctagttttgg tccgtaaaag gctgcctcgc cttctgcttc
     1621 aaagtaatct agttctaatt catccatagc ggctttcagc attgcttggg ctttttccca
     1681 cattgcgtca tcatcaaaat atttatctgt attgtttgga tcgcgatagc tcaagcggaa
     1741 acgataatct gtaatattga agtcagcata tactgccacc atcaattcaa gcgtacgttt
     1801 aaattcatct ttgatttgat caggacgaac aaatgtatga ccatcattca acgtcatttc
     1861 tcgtacacgt tgtaaacctg acaaagcacc tgatttttca tagcgatgca tcattcctaa
     1921 ttcagcgata cgaattggta attcacgata agaatggatc gtgtttttgt agaccatcat
     1981 gtgatgaggg cagttcattg ggcgaagaac aagcatttcg ccatctccca tatccattgg
     2041 cgggaacatg tcttcttgat aatgatccca gtgtccagat gttttgtaca actcaacatc
     2101 tcccattatt ggtgtatata catgttggta acctagacta acttctttgt ctacgatata
     2161 acgttcgatc gtgcgtcgga ttgttgcccc ttttggaagc cagaatggca aaccagaacc
     2221 tacttctggg gaaaccatga acaagtcaag ttcttttcct agtttacgat ggtctctttc
     2281 ttttgcttct tcacggagac ggatatattc tttcaaagct ttcttgtcaa aaaaggctgt
     2341 cccgtataca cgttgcatca tttgattgtt tgagtttcca cgccaataag cacctgccac
     2401 tgataataat ttaaatactt gtatacggcc agtggatgga acatgtggtc cacgacacaa
     2461 atcgatgaat tcgccttgtt gataagcagt aatcacttct tcttctggca attcactaat
     2521 cagttctact ttgtacggat cacttgcaaa aatttctaat gcttcctgtt ttgaaagaac
     2581 acggcgttcg atcggcagat tttctttgac gattttcatc atttctgctt cgattgccgg
     2641 caaatcttct gcagttactt ggttttgtcc attatctgta tcgtagtaaa accctgaatc
     2701 gatagctggt ccaacgccaa agtggatatt tggatagagg cgacgcatgg cttgggccat
     2761 caaatgagct gctgaatgac ggactaagcc aagtgcatct tcatggtctg gtgtgatgat
     2821 ctcaatactt gcatcttcct cgattggacg agtcaaatca acgagttttc cgttcacttt
     2881 accagctaaa gctttttttg ctaagctttt tgaaatgctt tcagcaattg ccaatgttgt
     2941 tgttccagac tcaaattctt tgactgcacc atctggaaaa gtaattttta tcataatagt
     3001 ttcctccttg aaatgttttg attgatcaga tcatcaagct gaaaaacaaa aaaatcctag
     3061 catctcttga aaagagatac taggacgaaa agttcgtggt tccacctaat gttcaaacgc
     3121 aaatgcgttc ctcaagcgtt gtaacggtcc gaccgccctt gcttcaacaa gggtttcgaa
     3181 agtggtcatc ctttggtttt ctcctggaaa agtttcagcc tagcttttcc tctcttatcg
     3241 aagactctca aattcagttg gctttctcat caatcaatta tgtgtttatt taaccactaa
     3301 taaatagaaa aatcaagtgg gaaactaaac ttattttttc cattccccat ttacaccgta
     3361 tgttcctttt ttcatctcat tgatgatgac atggatgtgt tcttttggtg cctgcgtgtt
     3421 tttatgaaca gcttccgtga tatctttcat catattttct aattgttccg gactgcgacc
     3481 ttctactaat tcgacatgta cgaatggcat aatgctctct cctctttctg atcgttcttt
     3541 tttcaactcg attctatcat actatgtttg tcttgggtac tgaatcagga aaaatggctg
     3601 gatctttttt tgctctcaag gcactcaaaa tagagaccgt atccacgact tcttgcaaaa
     3661 cagctccgaa taatgcgggg attagtcccg tacttgcaat taacatcaaa aaaatacaaa
     3721 taaagatgcc aatcagtaca gactgtttcg ctattctcat cgtatctctt gaaatcacta
     3781 ctgcttttgc tacacgcaag agatcatctt tcaagatgac cgcatctgca ctttcactag
     3841 cagctgtaga accatgagcc cccattgcaa taccgatatc tgcagcagca agtgctggtg
     3901 cgtcattcac gccgtctcct accatcgcaa caggtctttg atctttaggg atactttcta
     3961 aaatggtcag tttatcttga ggcaagctac gggcatgtac agaatctaat tggacttttt
     4021 ctgcaatcgt ttgagcaatg gcagatccat ccccggtgat catcatcaaa tttttcacat
     4081 caagttttct tagctccttg attgtctttg ctgcttctgg gcgaatctga tccgaaaata
     4141 ggatcgttcc tgcaaaagat cgatcaattg ttacatagat tgctgtattg gacgtttcta
     4201 tttcttcagc tgaaacaaaa gaggcacgtc caatctttac ttcatgatta ttgactactg
     4261 cttggattcc ttgaccggtc acttctttca gttgactaac aggatacagt tggctgtttt
     4321 tcacgttgtt cactaacgaa cgagctaaga tatggctaga ttcctgttct gcactagctg
     4381 catacagaag tagctcttct ttttttattc cattgactgg ctgaatcgcc tctacttcca
     4441 atatcccttt ggtaagcgtt cctgttttat caaaagcaat cgtttttgta cgtgcgagct
     4501 tttcaatcgt tgttccagtt tttacaacga tcccgttttt acttgaacgg ctcattcctg
     4561 caactaaagc aatgggcgca gctagaatca gtggacaagg tgatgccact accagtacct
     4621 cagcaaatcg taaagggtct tttgagaacc accaagaaat accaccgatc aaataagcaa
     4681 tcaacgtgaa agggactgca taacgatcag ctaaacggac aaatcgggca ggcttttctt
     4741 ttgattcttc gactagttta ataatcattt gatactggct gtctgcggca cgtttttcag
     4801 cgatcatttg gatcgatccg tctccattta aagaccctga cataatctga tctccaggtt
     4861 tcttggtttc cgggcgggac tcacctgtca aagaagattc atcgaccgaa gattctcctt
     4921 tggtcactcg accatctgcg ggtacaagtt cgccaggctt gactagtaac tggtcatcaa
     4981 tatttatttc atcgattact atatcctgca attttccttc tttgaatcga tgggcaattc
     5041 ttggggtgtt atctaacaaa gactgcagtt ctttacccgc tcgtttattc gcgtaatcct
     5101 ctagactatc tccgcccgta agcatgatca atatcatcaa actagcccag tattctttga
     5161 cggctaatgt tgcaaggatt gcggtaatcg ctaatacatc tacgccatat cttcctgaac
     5221 gtaacgtctt gatcatttcc aaaaacatca agaaggcgag aatccctcca gtaaatgcga
     5281 caatcgcaaa tgcaagggcc ggctggtgaa aaacaaattc acttaataaa gctatcccac
     5341 caataagcaa agtaagtaaa aattttttga aatgtgtcat tgttttttct cctcttttat
     5401 gtgacttaga gaggttagta ataaatttcc agctgcctct ttcatcttaa gcatagtcct
     5461 tgactagcac tttttaaaac aataggcctt aattgaaaac aactatcact atcagcgttt
     5521 ccaaaattca tcagttctac aaacaaaaat attcagcaag gattactttt tcgattcatc
     5581 agttaaaaag tacctttttt cgaaaaacta tgctatactt ttaattcgtt atttacggcg
     5641 gaaggagcaa acatgcgatg aatgagaaac aactagaaca aacgcacgtg gatgaaacga
     5701 tcgaactaat ccagatcgaa caaaatatgc tggatacaaa acaacaagaa ttgactcagg
     5761 aaatgaatca ttcgacaaaa gacacagcta atcacaagat tcgagctggt tccaatgaag
     5821 ctttttatga atctgctgtt gaatatcgcc aacatgagca ggaattgctt ttgaaatacc
     5881 atactcttga agcacagcaa aaacgcctgc aaacgttgtc tgtcatgaaa gatagtcctt
     5941 attttgcccg tatcgacttt aaagaagacc gtgaaacaga aacattatat ctaggtatcg
     6001 cttctttaag agatctggca gaagaaacaa tcgttattga ctggcgcgca ccaattgcca
     6061 atctttatta tgaaggtgag attggtcccg cattttatga aactgaaaca gatagaatag
     6121 atgtcgatct gcagttgaaa cgacaattta aaatccaaga aggacgtatt ttatctatgg
     6181 tagatacgtc ggaagtaatc aatgatgact ttttgctaga gatattggat gaatcatcaa
     6241 gcaaccatat gaaaaacatc gtctctacga tacaaaaagc acaaaatgca atcattcggg
     6301 acacaacaag taaagtaatg ctgattgaag gaatcgccgg aagtggaaag acatccgctt
     6361 tgcttcaacg tattgctttt ctgttgtatc ataatcgcaa gtggctcgag gctgaaaacg
     6421 ttcttctatt ttcacccaac catttgtttt ctgattacat ctcgactgta ttgccttcat
     6481 taggtgaaag cggcgtgcct acacagacat tcaaaaatta tttggtgcag ctgctgccag
     6541 agttttcttt actagatgaa cagcaacaag aaagtggttt tttgctaggg gaaaaagatc
     6601 cgatacaagt gatgaaaagc ggattgacct tagtcgatca gattgatcgc tatatccaag
     6661 gcatcacaaa ctacggtccc ttgttccgtg atatgaaaat aaatggccgt acgatcctat
     6721 caaaggaatc gattcgccaa tggtataaag aaacaaatga acaattacct ttacatcata
     6781 gactttctct attacaaacg aagctcctga aaaaattagg cggtctgcaa aaagacgaaa
     6841 cacgtcagca atgggtcaaa gatctggcgg aagaacagct ccaagaacta tacgcaacag
     6901 atccaaatct tgaatataca gaacaaaagg agcgttcatt acgtaaaaaa ctggccaacc
     6961 aaatcgtacg taaaagattc cgtcgaatcc atcgagggat catgaattat caatttgtca
     7021 atataacgaa acaatatctc cactttctac aaactgtgcc actttctctt ctaacacgac
     7081 ataaaatcag cgagaccagg tggcaggaac atttgacaac tgttcgtaca cacttgcgtc
     7141 aaagagaatt gcgtcaagag gatgctgtac tattcttttt actgatgcgc cgaacatatc
     7201 cagtgacggt tacacacaaa gctcgctata tctttattga tgaaatgcag gatttcgcac
     7261 catcacaagt ggcattgctg caagccttgt tcccaaaagc aaatttgact ttctgtggag
     7321 atctaaatca aaatgtcttt ggaaatgaaa cgatcgttgg atcattggaa gaccttttcg
     7381 tggaccgtga agtcactcgt ttccaattaa cgacaagcta tcgctccaca aaagaaatca
     7441 ctgattttgc taatcatttt attgtgaaag aacatcaagt agaaacaaca gcaagaaaag
     7501 gagaccttcc tttgctcatc caaggaacaa cagatgatat caaattgaat tggttagcag
     7561 ataccattcg aacgactcag ggaaaagccc ggtattggcg tacagcaatc atagctaaaa
     7621 cacaagaaga atgcgaagct ctttatgctc aactgccaga cgagttgaaa caacaagtcc
     7681 agctgatttt aaatgagagt gactttatga agcgttccat tattttactt ccagcctttt
     7741 tagcaaaagg tctggagttt gaccgagttt tcttgtggga tgtagatgca gaacattttt
     7801 cttctcagca agacaaattg atcctttaca ccatgtgtac acgtgcgatg catgaattga
     7861 ccctttttac ctccaataat gaaagtcctt tgttaaacaa tatggatatt tcatcttatg
     7921 agaaaaaagt actgtaagta aaaagacaac tgctatcatt aatgttagca gttgtctttt
     7981 tatttacaat aataattgca gaaaaagtaa ttcaatcatt taaggtcatt tattctatat
     8041 ataaatccaa atctgtttca ggatatttta atttgacaag cgaaataatc attttcagtt
     8101 cttccatgtt ttctggatat tctgggtcaa ataccttgct atgacggcca atcccgccat
     8161 tgtcgatcaa tcggtaaatt cgattccatt caatgaattg gtcaattgat tggaaattgc
     8221 tgattggata gccgccacaa tccaaaatct ctgatacacg aaatgctagg tatgcactat
     8281 cgatcacttt attttttttc gtgtctatct tctcatttct ttcgataaga attttttcag
     8341 gacgatgttt caagctccac tctaatagta gaaagaaagc ctccatccga tactcttctt
     8401 caaataaccg aaaggctgaa tcagaacgac gaaaaagcag cggaatcaga taattttgtc
     8461 tataaatcag cattggtgcg cggtccacca tacactctaa ataacggttc agataccctg
     8521 taccgacata gtttcctaat cgatagcctt caacgccgaa tcttgcgtat ttttgcgcta
     8581 attttgaaca atcagttacg ttcacagcta actcttctac tttgcggtaa ccgcttaaga
     8641 tacgttcaaa aggttctaaa gtgatttttg cttccatatt cttccccgtc catcttccac
     8701 atacttcata tcatttcaca tgatacttat gctctcatca taccacaggt tgaattagaa
     8761 aagaaaataa atcacacaaa aaagcaagac aatctgttag tgagattgtc ttgcttttcg
     8821 aaaaagactg aatacttttc gttaaaactg gttgcttagt cttctaatgc cacattatgg
     8881 aacacatgct gtacatcttc tagatcttcc agtgcatcaa tcattttttc aaatgtttct
     8941 tgatcttctg gagatagtgt tacctcgttt tgagggatca tttggatctc agcgattgaa
     9001 aaatcagtga ttcctttttc ttttaatgct tcttgtatac tatggaaatc cgctacttca
     9061 ccgtaaacga tgatttgtcc ttcttcttcc attacatcgc gaacatcgat gtctttttcc
     9121 attaggtatt caaggatctc gtcagcgtct tctcctgcaa aagcaaagat tgctgtattg
     9181 tcaaacatgt aagaaaccgc tccggaaaca cccatgttcc cgccattttt cccaaatgct
     9241 gcccgtacgt ctgctgctgt tcgattcaca ttgttcgtca atgtatcaac aatcaccatt
     9301 gagccgcttg gtccaaatcc ttcatagcgc aattcagagt atgtttcatc tcctgcacct
     9361 tttgcttttt cgattgctcg gtcaataata tgttttggta cattataagt tttagcgcga
     9421 tcaatgacga aacgtagttt ttggtttgca tgcggatcag gatcacctga ttttgctgcc
     9481 gcgtagattt caatcccaaa ttttgcataa atccggctat tattagcatc tttagcagtt
     9541 ttctttgcta cgatatttgc ccatttacgt cccatatttt cacttcgctt tctgatttga
     9601 tagtttcata acgcaaaaac gtcctgttcc attatacttg tgaatcacga ttctgtgaag
     9661 ctttttttct ttcttccttc attcttctca tttttagtca attatctata ctcggattgg
     9721 gatttgcccg aaattctgtt ccggaatatt gcctcccaat tgatagattt gatcacttct
     9781 aactaacagt tccgcttctt gtgcctcttt ttttccgatt cgggaataaa tagaaatctc
     9841 ttttttttct tttaagaatc ttcttccagc atcggtaaat ccaagtagtc gaagataatt
     9901 tttattttgt tggacaggaa tctcttgctt tttgatattc agcaagacat aacaagataa
     9961 tcgttggatc cgtgtccatg tatatctttt tgtttttacc tttgacacaa aatcctcaaa
    10021 actatcagca gttgcagctg ctgttttcat gcgcgattct attccttcgg tcatctgata
    10081 gatatctgtc agttccagca aagtagaaga taacaaccga taacgcaaat acggccaata
    10141 agattcccaa gtctgcagcg aacaagttga aagatcttct tctgtctgag gcggcacaag
    10201 tccagctatt ctttttcctt cttctaacgc atggcgaatg gctgttgcac tggctatcct
    10261 ctgatctgtg atgatttttt catgatagcc tgcactttta cgtcggatcg gatgtaattc
    10321 catagggtgg acatacttgg cattttcctt tgcataactt aatcccaaga tatgatttgg
    10381 cgaagaaaaa tcaagcgtaa tatcgggata cagactgcga aaaacctcag tcattttttg
    10441 cggataacta tacgtttgat cagacagttc ttgaaatgcc tcttctatcc tatcttgatt
    10501 ctcttggaca aagcgtccga aactgctgta atcaaacgaa gtctcttctt ctgttccaaa
    10561 acacaaactg tcacagtcca gtgtttgcaa gatttttact gcacctttag caaaatagtc
    10621 agctgactga accgcccatt cgacgggaag ctccactact aaatccacac cattttgtaa
    10681 agcttcattc gcgcgatgcc atttatcgat gatagccggt tcgcctcttt gcaaaaaatt
    10741 cccgctcatt acagcaatga cgacctctgc tcctgttatt tttcgtgcca tttccacatg
    10801 atagcgatgt ccattgtgaa aaggattgta ctctacgata atcccgcagc ttttcatgcg
    10861 catcctcctt catagttatc gataaaaaag aaatagagac aagtaaaaaa aggcaaaaat
    10921 cggaaaaaat acccgaacta tataaactat tctcgcaaac acaatacttc tgcgacgaaa
    10981 agctgcactg caagagcaat gcctatatcg ttcggatata taatttatgt tgaagattta
    11041 ttcttttctt gttaactcga gcaggcaaaa ccgctagtct ttgtatgcta caaagaacca
    11101 gcgctttgat ttctctgatg ctgcttcgtc tgtaaaatca gaaaatgctt cgactttcga
    11161 aaagccgctg ttttccagca ttcttaaata actttccaat ggataggtac gctcttgatg
    11221 tagttcatct tcacgaataa atcgaccaga cccttcttgt tcttcaacga aaaaggtaag
    11281 aaaatgttcg atgctgtgtt tctcgcttcc tggataacta tcccacaaaa aagcaaaatt
    11341 atccccttga taatgatagc tatattctgg aaaaacctca tctacttgat aggtggagtg
    11401 tacgtcaaat aaaaatcggc cattttcttc taacgcttga tagacttcat caaacacttg
    11461 ctgtacctct tgtctatttt tcatatagca cagcgaatca gaaaaacagg taattgcctg
    11521 atattgtccg atttctgata aatcgagcat attgccttcc acaaattgga tcgatgcgtc
    11581 ttcttcatat gctcgctggc tggcaatcat caacatctct tctgaaaggt ctaaccctgt
    11641 cactttatat ccatcttttg caaaggcaac cgctaatgct ccagtaccgc atgccagttc
    11701 caaaatattt tttgtgtctt cttgtaaatg acgtttcgaa aaagctaacc attgctgata
    11761 aagtgtttcg tccatcactt catcgtaaat gaaagcaaat gtttcataag ccatatgtta
    11821 atccaaccat tcactaagat cgactagcgg agcatctgac catagttttt ccagattata
    11881 gaaatttcgt tctggcgcat ggaaaacatg tacgatcaca tctccaagat cgatcaatac
    11941 ccattttccg ccttcttttc cttcaatacg ttttacttca tatttgtttt cttcttcttt
    12001 atcaatgatt tcttctgtaa ttgcgttgat ttgacgttcg ctatttgctg aacagatcat
    12061 gaaataatct gccaacaagg aaacatttcg aacgtctaaa gcgataatgt cttctgcccg
    12121 ttttgaatct gctgcttcaa tcgcaatttt taattgttct ttactatcta tgatgatttc
    12181 ctcctaatat gagcagctta tttttttgct acccagtaat tatatgtttc gattgttttt
    12241 ggataaatct gttgttcttg cgcaagcaaa tgggccaatg tatgttttgt ttcaaatgct
    12301 acagcttcgt ctagatcagc ccatgcaatg gctcgtgcat cttgtacccc aggaaaatct
    12361 cgacctggtt caatatagtc tgctacataa atgattttgt caaggagact catcttagca
    12421 gccccagtcg tatgcacccg gattgcatga agaatctctg catcggtgat tcctaattcc
    12481 cgctctacaa acgaagcgcc aacaagacca tgccagattg cattattata attcaataac
    12541 tccggatcaa aaccgtctct tacgattacc attttgaact cctcatctgg tcgttctttt
    12601 gcataatcat gtgtcaatgc agcaatacta gctttttcag gagaagcacc gtattttttg
    12661 gcaagagcca cggctgtttc ttctactcca agcacatgct tgaagcgttg ttcgctcatt
    12721 ctcatctgta ttttttgcat caggttttct ctagaataag cagtatattc attactatag
    12781 tccatattca tacaaccctt cattttgaat ataatcaatt actttatctg gaacaaggta
    12841 gcggatagaa cagccttctt tgatcttttg acgtattttc gtggaactga tgtcgatctc
    12901 aggtacatct acccaaatta caggatatgg agtatccgtt gtgtatcctg gtcgacgtat
    12961 acccacaaag ttgaccatag aagtcagctc atcgatttta taccattttg gcaaatattc
    13021 taccatatcc ccaccgataa taaagtaata atctgtatcc ggattgtttt gcgtcaattc
    13081 cttcatagta tcataggtgt aacttttccc accacgagct aattcaatcg tttcaatctg
    13141 caaaaaagga ttgtcttcca ccgctaattc caacatgttg agtcgatgtt ttgcatcaat
    13201 cgtctgtttc tcatcaacat gaggtggctg ataagaaggc atcaaaaata cgcggtcaag
    13261 acctaaattc cggccagctt gttcagccat cactaaatgt gcaaggtgaa cgggattgaa
    13321 tgttccgccc aagatcccta cttgcttttt cttctctaag aattgaggca tttcttcagg
    13381 aaataattgt gaacgaacaa atgtcttagc ttgcgtattc atcatggtca ctccttatat
    13441 tgcttttact tcttttgata gcctttgata cttttctttt gtggaaggtt tgtataatac
    13501 aataacacgt ccaatgattt ggacgatttc gcaatctatt tctttttcta atacttgagc
    13561 tgcttcttct gcaatctcat ctgtattttg aagtaacgat actttgatca gttctctttt
    13621 ttctaaagct tcttcaattt gaacgatcat tgctgaattg atcccacctt ttccgatttg
    13681 aaaaatcggc tgaagatgat gcgctttgct acgtaaaaaa cgcttttgtt ttcctcttaa
    13741 actcataatt ttccttcttc cttaaatcaa tgctttgcgt ttcaatacat ctacaccctt
    13801 tggcgcccag cccgcaatta ctactggcgc tgttacagtg atccagccta gaccggcaaa
    13861 aacgatgtct gttttttctt tcacagaaaa ctcaaaacga acaagctccg gaaatgcctc
    13921 gacttcatca ggacgaggag gctgtaataa tccacctaca tgtttttgat aaaattcgtc
    13981 tgctttttcc agtttcgttc gatgaatatt tacatcattt gacacataag caataaatga
    14041 agcacgattg ccgctgataa aatcaaatct tgcaagtccg cccaagaaaa gtgtttgccc
    14101 ttcattcagc tgataaactt taggtttgat ttcttttaac ggtgcaatga tccgcaaatc
    14161 ttttttacct aagtagtgcg ccatttgatg gcgatggata attcccggtg tatcaatcaa
    14221 aaaatgcccg tcatctaaag gaatctcgat tttatccaag gtcgttcctg gaaactgcga
    14281 agttgtgatt acatcttgta ctcccgctgt atttttgatg atttgattga taagcgtcga
    14341 ttttccgaca tttgttactc cgacgatata gacatcccgt ccatcgcggt attcttcgat
    14401 tttttctaat agttccgtca tctcatgaga tttcttagca ctagttaata atacatctac
    14461 tggacgaatt cctgcttcgt aagcacgttc cttcatccat tgtgttaatt tagttttttt
    14521 caatgattta ggtaatatat ccactttgtt cccaactaaa agtactggat tgtcaccgac
    14581 aaaacggtgt agtcctggga ttagtgaacc attgaagtca aaaatatcca ccacattgac
    14641 gatcaatgca tctttttgcc ctaattcatt cagtaagcgc aaaaagtcgt catccgtcaa
    14701 tgagacatct tgggtctcat tataatggcg taatctgaaa caacgctgac aatagacttc
    14761 cccggaagct aaaccttttt ccaaagccgt ttgcggcgtg tatcctaatt caccgggttt
    14821 gtttgtttgt ataacggcac cacagccgat acattgtaat tcttctgtca ttcgattcca
    14881 cctcgccagc ccatatcagg gtgttttgct aatagatagg ccataattct tttttcccaa
    14941 aaacgattaa attgtgtctt ccaactatct gttgcgataa tgggttttac aaggatgcta
    15001 cgtatccctg cacgattggc tccacgtata tcagtcataa tctgatcgcc taccattact
    15061 atctcatcat ctgctaaatc caattgtttc tttgctatgt tgatccctct tgctaaaggt
    15121 ttcattgctc gtgcaacata caaaagatca aatttttcaa tcgctcgcgc gacacgtttt
    15181 gaattattgt ttgaaacaac aacaacaggg attcctgcat ttttcatttc taaaatccaa
    15241 gtaagcaact cttctgttcc atctggatta ttccatgcaa tcaacgtatt gtctaaatcg
    15301 gtcaatactg ctttgatgcc tagattcttt aattgggcag gtgtaatctg atagatggct
    15361 tctaccatcc atgttggttt gtaatttgaa aacatgctgt ctcctcatct gcaaaaaatg
    15421 aaggagcaca taaagtactc ctcaaccccg tattatactg catatcagca aaaaaaacta
    15481 cctctatact cgttcgtctt tcagaaaaag catttcttta caaaatgacc aaaaataaag
    15541 attgatcaca gaaaaattta gaaacaaaaa acaactaata ttggcggaac ctcttgtatc
    15601 gtttttccag taatttatgc tgatctaatc gaacaagttc cgtcaatctt tcaatcaacg
    15661 cttttttcat aatgtgtgcg actttatatc gtggcaactg ctcgccgttg aacgtttcag
    15721 gaataactcg atcaacgatt cctaactcgc gtagttctgg cgcagtaatt ttcatcaact
    15781 cagctgcttc tgcggcgcga ctaccgtctt tccacaaaat cgacgcaaat ccttctggag
    15841 aaagcacagc ataaatcgtt tcttccagca tccagacttc atccgctaaa cctagagcaa
    15901 gggcaccgcc acttccacct tcaccaatga tgatggcgat gatcggtacc tttaaatcag
    15961 acatttcgag cagatttctg gcaatagcct ctccttcgcc gcgctcttct gctcctacac
    16021 cgcaataagc acctgctgta ttgatcaagg taatcaccgg tctattgaac ttttccgctt
    16081 gtttcatcag tcgtaaagct tttcgatagc cttcaggatg gggagaacca aaatttctgc
    16141 ggatattttc ctgcagatcc cgtccttttt gaataccgat cactgttacc ggtttgccat
    16201 ctaatcgagc gattccacca acaatcgctt cgtcatctgc aaataaacga tcaccatggc
    16261 attcctcgaa agaatcgaag atctcttcaa aaaaatccaa gcttgtccat cgttctttag
    16321 ctcttgctaa ctgaacgaca tcatgtgctg tcttatccac gatctatcca tcctttctgt
    16381 gtatgcaatt caagaagcgt atggattttc tgtttcaatt ccatgcgggg aacaatctga
    16441 tcgacaaaac catgagataa taagaattca gccttttgga aatcttctgg aagttcctgc
    16501 ttgatcgtct gttcgatgac gcgtcttcca gcaaaaccga tcaagctttg gggttctgct
    16561 agaataatat cgccttccat tgcaaaactg gcagttactc ctccggtcgt cgggtccgtt
    16621 aaaacagtta gataaaaaag accttcattg ctatgccgtt tgacagcagc agagattttt
    16681 gccatctgca ttagagaaaa gattccttct tgcatccgtg cgccacctga agctgtgaac
    16741 aagacgactg gaagactttc ctttgttgct cgttcgaata atctggtgat cttttctccg
    16801 acaatcgttc ccatacttcc catgataaaa ttaggatcca tcactccaat aatgaaggga
    16861 atcccctgaa tggttgcttt accagtgagg actgcttcat gaagtcctgt tttatcttgc
    16921 atttttttaa ttttttccgt atattcggga aatgctagcg gatctttggt tacaagatcc
    16981 gtatcccatt cttcaaaact tttttcatca ataatcaaag ctagacgctg ccatgcaccg
    17041 attcgaaaag cgtatccgca atgagggcat actttttctt caccgatgtc tttcgtataa
    17101 aggatatgtt tgcaatttgg acactttgcc cacatgttat caggaacaga tggcgagtta
    17161 gcaggtttgc tctctctatt aggattgatc cgaatatatt tctttttctt aaacagagcc
    17221 atctatgcgc ctcctatctc cgtttctggt gtccaattcg gtaaaaattc ttcttgtaaa
    17281 aatgctgtgc tgtaatcacc tgctatgact gcaggatgac taatcaaatc catctgaaat
    17341 tctgcgttcg tgatgattcc ttctgtgata aattcactta aggctcgctg catcttcatt
    17401 aatgcttcaa aacgcgtatt tccatggacg attatttttg caatcattga atcataatat
    17461 ggcgggatcg tatatcccgg gtaaactgca ctgtctactc gcagtcccat cccacctgct
    17521 ggaagcagta agttttggat cttccctgga gaaggagcaa aatggaaagc aggattttct
    17581 gcattaatcc ggcattcgat tgcgtgtcct tggaatacta cttcttcttg acacacattc
    17641 aaaggctcac cggctgctat ctccacctgt ttttttacta aatcgattcc tgtgaccatt
    17701 tctgttactg gatgttccac ttggattcga gtattcattt ccatgaaata aaaatcgcct
    17761 tcttcatcca tcagaaactc gatcgttccg gcattttcat aattgactgc tttagctgct
    17821 cgaacagcag cgtctcctag tgcttctctt tttgtttgtg agatcactac agaaggagat
    17881 tcttccagta ctttttgatt gttgcgttgt aaagaacaat ctcgctcgcc taaatgaatg
    17941 acatgaccaa atcgatcacc taagatctga acttctatat ggcgagcagg ataaatgatt
    18001 ttttccaaat acatatcatc atttccaaat gccgctgctg cttcttgctg agctgaagaa
    18061 aaatgctgtg ggagctcttc ttttgattga actttccgaa tgcctttccc gccaccacct
    18121 gcagctgctt tcagcatcac tggataacca attctgtctg ctatttccaa tgcttcttct
    18181 actgtagata atacaccagt acttcctgga atgactggga catttgcttc ttgcatcaat
    18241 tgacgcgcat tgatcttatt tcccattgca tcgatcgttg cacttttagg accaataaat
    18301 gtgatattgc actcttcaca catggaggca aatcggctat tttcagataa aaaaccaaat
    18361 cctggatgaa ttgcttcggc ttttgtcacg attgcagcgc tcagtacttc ctgaacattc
    18421 agatatgaat caacggcttt tgccgggcca atgcagattg cttcatctgc taactgtgta
    18481 tgaagtgctt cggcatctgc ttctgaatat atcgctacgg tttggatccc tagttcgcgg
    18541 catgcacgaa tgatacgtac agcgatttca ccgcggttag ctatcaatac tttagaaaac
    18601 atatttcacc tatccaatca taaaggttaa ttccgcttcg gctacttttt taccgtctac
    18661 tttagcgatt cctttgccta ttccggctga agctttcact ttcaatatct caacttcaag
    18721 gtataaggta tctcccggtg taactttctt acggaatttt gctttgtcca atccgccgaa
    18781 ataagccgtc tttcccttga attgttcaag agaaagtaat gcaactgctc ctgcttgagc
    18841 cattgcttca acaatcaata cccctggcat aacaggttct tctggaaaat gtccttgaaa
    18901 aaagggctca ttgatcgtta catttttctt agcaacgatc cgttctcctt caaccatttc
    18961 ttccactcga tcaatcaaaa gcattggata acgatgtgga atgatttctt ttatttcttg
    19021 tatgttcatt gttttccctc tttcctgctt tgcttatttt tgctgaatcc taaagagtgg
    19081 ctgtccatat tcgacaactg actcgttttc tacaaggatt tctgtgatca ctccgtcggc
    19141 ctcactagtt atctcattca tcagtttcat cgcttcaata atgcagataa cttctccttt
    19201 ggcaacttga tcacctactt ttttgaaagc tggtttgtcg ggcgctggtt gcagataaac
    19261 gattcccacg attggcgaaa caacctcgat tccatcaaat actgccgatt ctttttcttt
    19321 cattatttct ggagcagttg ttgcttgttc aggtatgaca ttgactggct ccgaaactgg
    19381 caacgtttcg tttgtttgaa ccatattcat gcctcgactt gttttatttt tattcatata
    19441 caattcaaat tgaccttcac gcaaatcgaa ttccgttagc gaggattgat caaattgact
    19501 gactaattct ctgatttcat tgatatccaa aattattcct cccagcgttt catgcacaga
    19561 accgcattat gtccgccaaa ccctaatgaa ttactcattg cataagtaaa acttgcaggt
    19621 ttgctttcgt ttttgacaac tgtcaagtca atctcaggat cttgtttttc tacattgatc
    19681 gtaggtggga taaattgatg ttctaatgcc agcaaagttg ccaaggcttc gatcccgccg
    19741 gctgctccca ataaatgtcc agtcatcgat ttcgtgctgc tgacgtaagt atctctgaaa
    19801 ttttcaccta atgcgatttg gattgctttt gcttctgcct ggtcattggc tggtgtactt
    19861 gttccgtgag cattgatata tccgacttgt tccggctgta caccagcttc ttccatcgca
    19921 agcttcattg ctttagatgc accagaacca tctggagtag gagctgtcat atggtaagcg
    19981 tcacagtttg caccgtatcc aacgatttct ccatagattt tggcaccgcg agcttgtgca
    20041 tgttctaaag attcaagaac tagaacgcct gctccttcac ccatcacaaa accattccga
    20101 ttttcgtcaa acggaatcga accacgatta ggatcagttg attctgagag tgctgttaaa
    20161 gctgcaaatc cagcaatccc catctcacaa atcgttgctt ctgttcctcc agcaagaatg
    20221 acatcagaat agccatgttt gatgttacgg aatgcttccc caattgaatt cgttccgcta
    20281 gcacaagctg ttacgatagc tgtacaaata ccttttgcac ctacacgcaa agcaatattt
    20341 ccagctgcca tgttggcaat cgccattggt acgaacattg gagaaactcg ttttgcacct
    20401 ttttcatgta gacgaataac ttggttttcg attgttggaa gaccaccgat cccagatccg
    20461 atgatgacgc caaaccggtc ttgattcatt ttttctttat ctaaaccgct catctccatt
    20521 gcttctaaag cagcgtagat tccatagatc gaaaacatat ccattcgttt gctatctttt
    20581 ttaataaaat atttatcgta agggaaatct ttgacttcac ccgctaaggt aatccctgtt
    20641 tctgaagcat caaatttagt gatcggtgcg atgccattcg tcccctcttt taagctattc
    20701 aaaaagctgt ctgcgtcatt tccaataggt gaagtgactc catagccagt aattaccact
    20761 cgattcattt gtttgctctc cttttcttat ccgtgcatga ccaatccgcc atcgacattg
    20821 atgacttgtc cggtgatata tggattttgt gctaagaaaa ctgctgtttg tgcaatatct
    20881 tctacttgtc cgaaacgctg catcggaatt tgcttttccg cttgttcctt gactttgtct
    20941 gctaaaactt ccgtcatatc agttgtgatg aatcctggcg caatggcatt acatgtaatg
    21001 cctctagttg cagcttctcg tgccacagat tttgttaatc ctactacgcc agctttacta
    21061 gctgcataat ttgcttgacc aatatttcca atcaacccag atacactaga gagattaatg
    21121 atggcccctt ctcgctgctt catcattttt ttcaatacgt gctgcgtcat attgaaggtt
    21181 ccaatcaaat tgatatccag acattttttg aaatcttctg catccattcg catcacaagt
    21241 ttgtcatttg tgattccggc attgtttact aacacatgga tcgatccaag cttttcttct
    21301 gcttctttga tcatttgtcc cgctttctca taatcagaga tgtcaccgga aactcctacg
    21361 cattttacac cgaatgcttc gatttcttct atcttttctt ttggaatctc tccgcgacca
    21421 ttcaaaatga tatttgctcc agcttttgca aaagctaagg ccatcgcttt gccgattcct
    21481 cttgtactac ctgtgataaa tacatttttt ccttttacat ccataacgtt cctccttata
    21541 gtattgctat tgtttcatca aatgtctgct tattctcaac acgcagaact ggtattgttt
    21601 tatcgatttt tttcataaat ccgcttaata cttttccggg gccgacttcg atgacttgtt
    21661 cgatgccgat tgtttttaac ttatggatac tctcatagaa acgaacaggt tgcatgactt
    21721 gctgttcaag tagtcccgcg attgtttctt tcttcattat ttccgttgtt gtgttgctta
    21781 tgataggaaa agaaggttca gagaattgaa tctgacttag gtccttcgcc agtttttttg
    21841 ctgccggttc taaaatagct gtatgaaaag gcccgctgac atttagaggg atcattcttt
    21901 tgaacccttt ttcttttaat agtaaaacag cttcgtctac tgctttttct tcgccaccaa
    21961 tcacgatctg ctgaggtgta ttataatttg caggagatac gatgccgtac ttgctagctt
    22021 catgacagct ttcctcgatc gtttcaatcg gcgcattcat cactgcaacc attttcccgc
    22081 ttccagctgg ggcagcttct gtcatataag cgcctctttt tgctactaac gcaactgctt
    22141 cagtgaagga tagcgcatta ctagctacta atgccgaata ttctcctaaa ctcagtccta
    22201 aagctgcatc tgggatgatt ccatgctcct tcaataagcg ataatacgcg atgctgactg
    22261 ttagaatagc tggctgtgta tattgcgtct gatccaaacg ttcattttct gtaaagcaaa
    22321 gttcagccat atcgtagccg agaatctcac ttgcttcatc aaatgtctgc tttacaacgg
    22381 cttcttcata taaatctttt cccatacctt gatattgtgc accttggcca ctaaataaga
    22441 atgctgtttt catgtttttc tccaatatat ccagaatata tgtttgattc ttcctattca
    22501 aaaaggccga gacattccta tttcaggaaa tgtcccagcc cccaacctaa ttttaatgat
    22561 tatgcagttt gtttttctac gtaagtcact aaatcttgaa ccgttttgat tccgtcttct
    22621 gtttcgattt tcacgtcaaa ttcatcttca atttcattga tgatttggaa taaatccaag
    22681 ctgtcagctt ctaagtcttc ttggatgtca gtagtcaatt tgatttcttc agtttctttt
    22741 cctaattctt ctgcgatgat ttcttgaatt ttttcgaata ccataataat atattcctcc
    22801 gatattgttt gctttttatt tttataattt aacagtctac aactccatga gaatacttcc
    22861 ccatgttaaa cctccgccat agcctgtaaa tattactttc tgctgttttc ctaaggtgat
    22921 ctttccacta gaaactgctt catccaataa gatagggatg cttgcagcag atgtattccc
    22981 atatttatcc atattggtca ggaacttttc ttgcggcatc tttacttttc gggcaatttt
    23041 ctcaataatt ctgaggtttg cctgatgcaa aagcagataa tcaactggtt tgtctttcat
    23101 gacttcttgg atattgtttg caacgtctcg tacggcaaaa tcaaaaatat ctctgccagt
    23161 catttgcaaa taatacgaac cttctgaatc ttctgaatag aacggatttt tattttgctg
    23221 gtagccagcg gtcaatgagc tacttctggt accgtcagct gctaattttt ctttcagcaa
    23281 ttttttctgt ggattcgctt ctaagagaat cccacctgct ccatcgccaa acaacacagc
    23341 agtcgtacga tcagaccaat cgattagctt agatagtgtt tcaccaccaa tcaccagtcc
    23401 cttagttgag ccgcagcgga tcattttttc agccatgctt aacgcataaa caaatcctga
    23461 gcacgcagca ctgatatcaa aagcgatagc atgagttgct cccaatttcc cttgtacttg
    23521 tgctgctaca gatggtgtcg tgtaatcggg cgacattgtt gctactaaaa taaaatccaa
    23581 atctttaggg tttagatttt tctgttttat caatttttcc gccactaaaa tgcataaatc
    23641 agaagtctcc tgatttgtta cacatcttcg ttcacgaata cccgtccttg acgaaatcca
    23701 ttcatcagag gtatccatca tcttggaaag atcattatta gtaataatct tttcaggaag
    23761 gacgctggct gttgcagtaa tcattccaaa ttgttccatt aaatatcctc acttatagtc
    23821 ttgcaagaag tcgtgcaagt ttttcagtgc atccagcaag gcatgctgtt cctccgtagc
    23881 cattccgtct aagatgttct tgaccatttc acgatgaaaa tgctgatgga cccgaaatag
    23941 taactttcct tttttcgtta gtcccaactt tacaacgcgg cggtcatctt cactgcggat
    24001 acgttcgaca tagccttttt ttactaactt gttaatagca gtggtcaagg tcccaacagt
    24061 aattgatagt tctttggcta cttctgaagt tgtttttttc ttgtacatcc cgattgcctc
    24121 gatcgtgtgc atctctgtga ttgacagatc tttgaattga gattttttca gctcagactc
    24181 ttcgattgtc aaaatatcat tgaagacact aacaagataa tcatttactg tttttaaatc
    24241 tggttccatg ttccaccgtc cactaattag tttgattatc aaatcttttg atgttcaaac
    24301 tatatcttaa cttttttcaa aatgcaacct taaaagatca tttttttact atatgagctt
    24361 tttttaagat tttactcatt taaaacaact gataaatcag catttataat ttcttttatt
    24421 agaaaaatca tctatctcac atattttgat t
//
LOCUS       DAZAOD010000030        23992 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000030 DAZAOD010000000
VERSION     DAZAOD010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.031"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="ACHDPO_001280"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="ACHDPO_001280"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFN3368919.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2476)
                     /gene="purK"
                     /locus_tag="ACHDPO_001281"
     CDS             complement(1352..2476)
                     /gene="purK"
                     /locus_tag="ACHDPO_001281"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFN3368920.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="ACHDPO_001282"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="ACHDPO_001282"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFN3368921.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3373..4680)
                     /locus_tag="ACHDPO_001283"
     CDS             complement(3373..4680)
                     /locus_tag="ACHDPO_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFN3368922.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4683..5264)
                     /locus_tag="ACHDPO_001284"
     CDS             complement(4683..5264)
                     /locus_tag="ACHDPO_001284"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFN3368923.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5380..5477)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5836..7128)
                     /locus_tag="ACHDPO_001285"
     CDS             complement(5836..7128)
                     /locus_tag="ACHDPO_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFN3368924.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7125..7748)
                     /locus_tag="ACHDPO_001286"
     CDS             complement(7125..7748)
                     /locus_tag="ACHDPO_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368925.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7751..8587)
                     /locus_tag="ACHDPO_001287"
     CDS             complement(7751..8587)
                     /locus_tag="ACHDPO_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3368926.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8604..9491)
                     /locus_tag="ACHDPO_001288"
     CDS             complement(8604..9491)
                     /locus_tag="ACHDPO_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3368927.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9507..10790)
                     /locus_tag="ACHDPO_001289"
     CDS             complement(9507..10790)
                     /locus_tag="ACHDPO_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3368928.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11473..12156)
                     /locus_tag="ACHDPO_001290"
     CDS             complement(11473..12156)
                     /locus_tag="ACHDPO_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFN3368929.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12174..12791)
                     /locus_tag="ACHDPO_001291"
     CDS             complement(12174..12791)
                     /locus_tag="ACHDPO_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFN3368930.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12801..13625)
                     /locus_tag="ACHDPO_001292"
     CDS             complement(12801..13625)
                     /locus_tag="ACHDPO_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFN3368931.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13618..14178)
                     /locus_tag="ACHDPO_001293"
     CDS             complement(13618..14178)
                     /locus_tag="ACHDPO_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368932.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14352..15308
                     /locus_tag="ACHDPO_001294"
     CDS             14352..15308
                     /locus_tag="ACHDPO_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFN3368933.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15613..16569)
                     /locus_tag="ACHDPO_001295"
     CDS             complement(15613..16569)
                     /locus_tag="ACHDPO_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFN3368934.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16673..17275
                     /locus_tag="ACHDPO_001296"
     CDS             16673..17275
                     /locus_tag="ACHDPO_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFN3368935.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17363..18862)
                     /locus_tag="ACHDPO_001297"
     CDS             complement(17363..18862)
                     /locus_tag="ACHDPO_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFN3368936.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18878..19402)
                     /locus_tag="ACHDPO_001298"
     CDS             complement(18878..19402)
                     /locus_tag="ACHDPO_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFN3368937.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19700..20449
                     /locus_tag="ACHDPO_001299"
     CDS             19700..20449
                     /locus_tag="ACHDPO_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFN3368938.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20440..21225
                     /locus_tag="ACHDPO_001300"
     CDS             20440..21225
                     /locus_tag="ACHDPO_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3368939.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21194..21910
                     /locus_tag="ACHDPO_001301"
     CDS             21194..21910
                     /locus_tag="ACHDPO_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFN3368940.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22012..23031)
                     /locus_tag="ACHDPO_001302"
     CDS             complement(22012..23031)
                     /locus_tag="ACHDPO_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFN3368941.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23050..>23992)
                     /locus_tag="ACHDPO_001303"
     CDS             complement(23050..>23992)
                     /locus_tag="ACHDPO_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFN3368942.1"
                     /translation="SESVGKILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWG
                     LVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIF
                     NIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTG
                     AEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSW
                     YYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDR
                     EALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
BASE COUNT         7088 a         5181 c         4199 g         7524 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc ttttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttt gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttc
     3241 cttcaacggt gttcaatcag ctgaccctcg gtattagctc aaacaaacgg caaaatacga
     3301 ggaactattt ttccgtttgt ttctctaaca atcaggtcaa aacgctgatt tcacaacctt
     3361 tcttttgctc tattacttct tgaaggcttc ttccaatatt tcttcatctt ttttcaatcc
     3421 attaaagatc aaattcaata tgatagccgt aatgctactc attacgatgc catttccagt
     3481 gaacatttgc aatgtttgcg gcatttgact gaataatgtc ggcgtaacat tgaaacccag
     3541 cccaaatcca acagaaacag caacaatcaa tagattttta tcattgctga aatcaacttc
     3601 caacagcata cggattcctt ggactgccac catcccgaac atgactaaca ttcctccacc
     3661 aagtaccggc tcagggatga tttgtgctaa cgcaccgatt ttagggaata atcctaaaac
     3721 aatcaagaag aatgcagaga aatagatggg ttttcttgtt ttgattcccg aaagttgaac
     3781 caatccgaca ttttgagaaa agccagtata agggaatgta ttgaaaatac cgcctaagat
     3841 aacggcaagt ccttctgcac gatatccctt tttcaattct tcttctccaa catttttccc
     3901 agtaatgtca ccaagtgcaa aatatacacc tgttgattct accatgctga ccatggaaat
     3961 gatgatcatt agtaaaatcg accatacgtc gaaagttggt ttaccaaaat aaaagggttg
     4021 tggaacatgg aacaacggcg catctccaat cgcgctcaga tcaatcattc ccatgaaagc
     4081 agctaagatg cttcctccga ctaaaccaat caataccgcg attgaacgaa tgaacccttt
     4141 tgccagcatt tgcacgccta caattaggag aatcgtcaca aatgcaagta gcagatttgt
     4201 tttgtcacca aaatcagctg ctgttgcatt acctccaccc attttctcga ttgctacagg
     4261 aatcaaagtc aaaccaataa cggtgataac cgttcctgtt actataggag ggaatagttt
     4321 tttaatttta gaaaagacac cagaaactaa cacaacaaag atcccagaag cgataataga
     4381 tccgtagata gctcctactc cttcattggt tccgatcaag atcagtggag ctactgcttg
     4441 gatcgcacat cctaaaacga caggcaagcc aattccgaaa aatcggttaa ctgtcaattg
     4501 caataatgtc gctaatccac acataaagat atcaattgaa atcaaataag tcatctgttc
     4561 ttgattaaag cctagtcctg taccgatcaa aagaggcacc gctactgctc ctgcatacat
     4621 cgctagcaga tgctgcagcc ctaaaaccgc agcttttcca ttttgtgttt ctttttccac
     4681 gattatgcgt cctcctcaag aaactcaact tgtccattcg tcaaggaagc aatacgcgca
     4741 agagaaacga ctctcaatcc catttcttca agtaactgac gtccatcttg gaaagacttt
     4801 tcgatgacga tcccgattcc ttctacttgc gctccagctt gctggcataa ttcgatcaat
     4861 ccttttgccg cttgtccgtt tgccaagaaa tcgtcgataa tcaatacttt gtcttctgaa
     4921 gataaaaatt tacgagaaat agaaatcgta cttgtcactt gtttcgtaaa agaataaaca
     4981 gaagctgtca ataattcttc atccatcgtc aaactttttg cttttctagc gaagatcatt
     5041 ggaacatcta attctcttgc agcaaataaa gctggtgcga tcccagaagc ttcaatggtc
     5101 acaactttcg tgattccttg ttctttaaat acttctgcaa accgttttcc catttgttcc
     5161 atcaatacag ggtctacttg gtgagtgacg aagctgtcga cttttaatac gccctcgcct
     5221 aatatacgtc cgtctttttg aatacgttca actaattctt tcactttatt tgctccttta
     5281 tcatttatta ataccgaaat aaccgctttt gtgcaaaaac ctactatgtt tctgttaaag
     5341 aaaaacaccc tccactttat cataagaaaa gaagggtgaa atagccaatc ttttacttat
     5401 agtccagcat ttacggtact ggctagaaac tgtcatccat attatgacga tatataagta
     5461 ggtatgtaaa actaataata gtgtaaattc attttcttgc aactgttttg cacgtgaagg
     5521 cagtttgcca tatttgaata aaaaatgttg tttcaaatat tgaaaacagt ctaacactac
     5581 tttctgaaac tgacaacgtg gtttacttat ttttttgtaa aatctaatga tttttaatgc
     5641 attattcctt tttgttcggg tttaaatagt tatttttatt ttctcctatc taaaaaagca
     5701 gcccacataa aaagaaggca tgacaaaaag catgtcatag cccctttttc cgaataaata
     5761 gtgttcaaaa gacagcctat cggcaataag gcaagatttt ataaactacg ggaagtaatt
     5821 tccgtaaatc tattcttatt cttttaagct gacaagctcg tcaatcacta ctgcttttcc
     5881 tgaagcaata gaatgatttg ctgcgattcc tgtcaaaatc gacaaaatac catctacgtg
     5941 agttgctgcc cgattccacg gatcttcttc tttttcttca ccaaatagat catctaataa
     6001 acgcggatct cctccgccat gtccgcccgc ttcttgttcg acgattacct catatggctc
     6061 accgaacatc ggatagacat ggatggactg aagaacggct gctccttcat cctttttatc
     6121 tccacctgca ttgatgtaag acttttcgat cactttcatt tcgatccgtc ctttgctgcc
     6181 attgaaagaa acattgaatc cttcccacgg catatacgcg tttagcgaat acgtcaaaat
     6241 cgcaccagtt tcatatttga ccgttacgcc tagtgtatct tcaatagaga tatcatcgga
     6301 aaatacactg cggtcacgaa tatatccact gtctttttct gcttctaaat acatttctcg
     6361 caattcctca ttggctgaca ggtctatagc aaatggatca gctttagcta gttcgcttcc
     6421 atagcatcga ctgtaaaata tttctactcc gcgtttctcc gcattatgca tcccataaaa
     6481 gtttaatcca ccgaatgcaa ataccttttg gggacggctg ttcaaccaaa aattcactag
     6541 atcaaaatga tgggtagatt tatgaacaag aagcccgccg ctattgtgct tatttcgatg
     6601 ccatcttctg aaataatctg ccccgtgttg cgtatttaac agccattcga agtggataga
     6661 aaacacatca ccaatcacat cactttctat cagttccttt atcttcgtgt gatacggtgc
     6721 ataacgataa ttaaaagtga ctcgcaggct tcttcccgtc tgtttttgga ccgttattat
     6781 ttcttgagct ttttcctcat cgatagtcag aggtttttcg caaataacat catatccttt
     6841 tttcattgca cgaatgatat aatcatgatg cgttcgatct actgacgtaa taatgacttc
     6901 agccggccgt acgtcatcca gtagttgctc aaattgtgat ggcatacatg tctttacttt
     6961 tttctgtcca tacttgttca caagtatccg atttgcataa tccatccttg tttgagatac
     7021 atcacaaaaa ccgactagtt cacaagtttg atgatacgta gaggcaattg cctcataaaa
     7081 aaaacgcgct ctcccaccaa gtccgacttg tacatatttt ttcttcattt aaagtcattc
     7141 tccttttctt ttaagcaaaa tactgtgaca aatggcagcc ctggatacag taatgcagtg
     7201 agtaaaaaat catgctgtat acaccagaac agtccataca aaaggcataa ataccacaga
     7261 aaccccttga cgttttttga caacagccag atattccttt tgatcaaata aacaagacta
     7321 tctgctttat cttctttgca gatatcaatt agcgtactaa aaaaactatg ggatacaaaa
     7381 agcaacagac acaatagaaa aggaatcaga taccaagctc caatctttcc cactaataaa
     7441 taccaatcaa ctgcaaaaat aatgacaaac agctgaaaca acgtaatgat gaaacacatc
     7501 cgtttgattt ttcctttcct ccaacatacc tttttttctg ccaagtaatg gacagataga
     7561 taataagaag gatacatcat caaaaaataa atcagataga caacacgagc agacagcact
     7621 aatcctaaag tgaacaaaca tcctagaact aaagcgaaaa gagcattact gataagactg
     7681 gttaaaaaaa tccgacagac atagtagttg agcttgtaaa gaaacatctc ttctattggc
     7741 tttttcatat tcagcccttc agaccgcttg tactgatccc ctggacaaga tatttattga
     7801 agaataagaa aatcagaaaa accggtagca gcgacaacgt agacatcgca aacatactcg
     7861 cgtaagtcgt actagatcca gcgtctgcaa ataatttgat ggcaatcgat accgtgtaag
     7921 atctcggctt gtttaaataa atcaatggtc ccatgaagtc gtcccatttc caataaaact
     7981 ggatgatgat cgtcgtgatg atcgaaggtt tcagcaaagg aaaaataatt ttggtaaaga
     8041 cactatactt gctgcatccg tcaataatcg ctgattcatc taactctttg gggatgctga
     8101 ccatgaattg catgatctgg taaatgaaaa atgcttgtcc aaaaaaatgt ggtaaaatca
     8161 gcggcacata cgtcccaacc aaattcagcc gattgtaaat aataaactgc ggaatcaaaa
     8221 tcacttgtgc aggaatcatc atcgttacta acatgacgac gaaccagaat ctttttcctt
     8281 tgaaatcgat tctcgataat gcgtaagcaa tacaagtcga gctcagaact gtccctatcg
     8341 tcgaaactgc agagatgaca aacgaattcc taaagaaagt aaaaaatgaa attccagcaa
     8401 accccgccca tccttttgcg taattttccc attgaaaagt ctctggaatc aaattcagcg
     8461 aaccactcat aatctcttga tccgttttaa aagaacctgc gatcatccat aagaccggat
     8521 aaatcatgac tagacctaat agcaaaataa aaccgtattg aaaccatttc gttactgtat
     8581 tattcatttc ttcctcctct cattcacaca acgacccatt tttttgatga tttgaaaatc
     8641 agaaaggtga cagctcccat aatcaacagc atgatccacg aaatagcact agcatacccc
     8701 atagaattaa aagaaaaagc ttggttatac acataaagag cataaaagtt cgtggcatca
     8761 ttcggaccac cttgggtaat gataaatgcc tgcgtaaaag tcataaacgc cgcgattgtc
     8821 tgcataacca agttatacaa aatgatcggc gaaagaagag gtaacgtgat cttgtaaaac
     8881 gtctgccatt tgttcgctcc atcgatctct gccgcttcat aatacgagcc tgggatctct
     8941 ttgatacctg cagcaaagat gatcattgcc gaaccgaatt gccaagcaga catcaaaaca
     9001 agagggatca tgaccagttt ttgatcgcta aaccaggaaa gcgcaggtgc gcctaatcgt
     9061 tccaggaaaa tattcactaa cccgttttta gaaaacaact cccgccaaac tagagcgata
     9121 gaaatactgc caccgatcaa actaggcaca taatacaaag aacgaaagaa agtcgttcct
     9181 ttgatattcc tcgttaaaag ataagcaatc aatagaccaa agatcagttt cacaggtaca
     9241 gatgcaaata catagagaaa agtgactcgg atggagttca aaaaacgggc atcactcagc
     9301 atctttatat aattatccaa gccgatccat gagactggat ttcccaaacg ataatcggtg
     9361 aacgaataat aaagtgacaa gatcatcggt atcactgtta tcaatagaaa tcctaggatg
     9421 aatggagaag caaatacgta accgaccaca ttgtcttgat ccaagaaccg ttttagtttt
     9481 tcttttttca tgccttcctc ctgctgctat cctagaatgt ttgacgcaaa ctcataaaga
     9541 ctctctgctg cttcttctgc tgttacttct tcataaatga ctttttcaac taaaagattg
     9601 tattggtctt gaatttccgg attcaaagca ctatcaaaga cattcacttc gccgttgtcc
     9661 atatcggaaa tcatttctaa ataatcaaat gtcgcttgca aagttgcatc atctgcacga
     9721 gcgagctgtt ctcgaatatt cgacatgatt ggtacaccac gttctccttt taaaatttca
     9781 ttggcttctt cactgttttg aaagaaatca ataaacttag cagcttcttc tttatgggct
     9841 gagctttttg ccatactcag catttgcgaa gaacgtaaag ggataccaga ttctccatct
     9901 gcttttctgc gaggtggatt aatcaactga atctccatat cttcaggagc ccctgacaat
     9961 atttctgtca actggttact tgatagaaac accattgccg cttctctatc cctaaccgcc
    10021 tgaaaagaca gatccgtcgt acttgcagct ccaccacctg gttctggatg ggcccctttg
    10081 tctaccagat ttttacgcag ctggaaaaaa tctgttagat agtctggatt ttcaaatccc
    10141 aagctgttag atagatcttc ccgattataa aaattcaatc ctttctcaac ttgtggtatt
    10201 tgaataatac agccagctat aaaatcttcg aatcttgaaa tagcatagat tcctaattct
    10261 tcagtgattt gatagctgat ttgttcaaat tcatcccatg tccaatttga agctggttca
    10321 gggatattta attgttcaaa tatattttta ttgtaagcaa tcgcaaacga attcaccccg
    10381 ttagacagtc caactaattg cccgtcgtaa gtcgtcgttg ctaaatagga ttcatctgca
    10441 ttagaaatat caattatccc ttgctccaca tattcatcta atggttcaat ctgattgatg
    10501 tattgaggaa attgattgtt cagttggaaa atgtcccaga tatcatctga tgctgctagt
    10561 gtacctaatt ttgtgtaata tccttcataa tcataaaatt cataatcgat cgtcacatgg
    10621 ggattttttt cttcataaag ctcgattact tttactgttg catcgtgtcg gacttgcgaa
    10681 ccccaccaag ccatgttcag cgtgattttt ttgtcatctt cttgcccaca agccgtcaag
    10741 aagaataaca taacacttaa agctaagatg attctcattc ttttcttcat tctctgcacc
    10801 tctacttcca ttgttatttt tcaatatact gtatttttat acagaacata tttattaaac
    10861 gatctttttc aaggggaata aaaaccaaga cttgccttat cgttctgcct aggatgaaca
    10921 actcaatact ttcaagaaaa attagatagt gctgattctt ctttcatcgc taaaaacact
    10981 tcttgcttca atgatgggag gataattacg caaagaaaaa aggatatcag acaactgccc
    11041 aatatccttg acatagctaa ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca
    11101 gaaaaataac tagtaattct gtatgaaatt aggtacaata tacacgtcga tgcacaagca
    11161 ttgactatgg caacttgatt ggtcagttcc cgctgacttt tcaagccccg acaatttagc
    11221 tgctactaaa ttgtcgggtg ccttttttag tttttattcg tttttcattc tatagaaagc
    11281 gcttcaataa atcaagacat ttttttgtta gaatgctaat aataacaaaa ggttttaact
    11341 cttcttatgt acattacagg taaaaaaaca aaaaaatttc tctttttttt gaattctgaa
    11401 caaatagtac tggagtacaa aagacgagga agagccacta tctgctcttc ctcgtctttt
    11461 gattctcacc tgttattcat gattcttttt ctcagtttcc cgatattttt ccattttacg
    11521 actaaaaagc tctccgctac ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat
    11581 ggtctcagca atactttctt ccgttggacc acctgtcgca atgataggaa gttcaggata
    11641 ttttttacga aaatggcgta ctgcttctgc agtttcttta cctgcactga tattgataat
    11701 cgaaatacca gctgctaact tttcatctat ttctgtatat ttcgacgtta ccgtactgat
    11761 aactggaata tcaactactc gacaaacttc ttttactgtc tctaaaggcg taggaccgtt
    11821 caaaacgacc cctaacgaac cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc
    11881 accttgtgtc aaaccaccac ctacaccgga gaaaactgga atgtcagctg cctcaataat
    11941 gcttttagta atcgctggat gaggtgtaaa aggatacaca gcaattactg cattcgcatt
    12001 tgtattacgt atgatcgcaa tatccgtagt aaagatgatc gaacggatca attttccaaa
    12061 tatcttgatc ccgcttgctt ctaaaatgat ttccggtact cttacgatat cttttctcaa
    12121 ttccgtcatg atttctggcg taaattgttc tgccatcagc cacttctcct ttgctatctc
    12181 cggtcatact gattcaattg atacgtctcg atgacctgga tgattttttg cgcataaccg
    12241 gggtctgtcg cataacctgc atcttgcaat gcttgtgcgg cttcctgata gttggtggcc
    12301 gtaatcactt tttcatacag cgcaggattc caatctactc cttggacgaa cagttgtgta
    12361 tggtcatcca tggactgttc ccatgaatca tacactttga agtctccttg gatagttatc
    12421 cattcttcgt taacaaattc ctttgtttcc aggcttactt tcttctgatc cccataagcc
    12481 ttgatcccga aaagattatt gtatttgcta gccaaggtac tttttcccca atttgattct
    12541 aatatagctt gtcctaaaat gatactagga agcactccat aaccatcttg tagttcttgg
    12601 gcatgcggaa caagccgttc aataaattgc tgatgggatt gcgcttcatt ttcttgctga
    12661 ttatcagtaa aaggagaaga cagattcttc aaggaaaaaa caaaggctaa gagtatcact
    12721 gctacaccgg caaccactgc tggccaacgg atattcttgc gcttttgctt tttccacttt
    12781 tttttcgcca tgatcaattc ctacttttca tttaattcat tcagatattc ttctagcgtc
    12841 aattggtgtt tggtgatata ctcagcgttt tctttaccga cataacgtaa gtgccaaggt
    12901 tcatatgtga tcttagttat atcttcgtgt ccttttggat aacgaacgat aaatccatac
    12961 tgcgcagcat tatctgcgat ccatttagct ccaggctgat ctccgtaact tgcatccaat
    13021 acagtagaag gataactgtt gtaccagttt tgatcgacga catcgactgc cagacctgtg
    13081 tggtgttcgc tgtatcctgg ctccgtaatc gtttctttag taatctttgt cgcctcctct
    13141 tctgatacac cttgacgact catcacatct tggacatttt gttcgaaaac ttgttgttgg
    13201 gatgatacag accggtaagc tgagaccatc actaatggaa atccagctgc ttcagcagcc
    13261 ttggcaaatg cttcatattc tggagcaatg cgtttgtcga tcaagtatcc gttacttaat
    13321 gatgccaatt gagtagactc atcaatttct ttttctaatt tgtgatctgg accaaccaaa
    13381 actagcttcc aatcgtctgt tttaacatct ggcaattgtt tggacgtacg atcttttgtt
    13441 tctttgtcct ttaccttgct gctggttgtt tgactgttct tttctttact agcagttgtt
    13501 ttggtgcttg ttcgttcgac tgcttgattg ccggcttgaa catgcgaatc atcatcgcta
    13561 aaaataacat agcccattgc tgcgatcata atcacaactg ctccaaatcc taaaaattta
    13621 ttcacttgaa aaatcctttc gttgttcttc acgttcccca ttcgcctcat gaacgtaagt
    13681 ttcttccaga ttttcattca cccaatcgag aagttcgatt ttttctcctt cgatctgttt
    13741 ttgaacatct gctggcagac gaaaattcaa aatatcatca tagccccatt catcatattg
    13801 aatacttact ttcaagtcaa ggtatctacc agcctgctga ttatttttca aagggatcag
    13861 ctcgactttt gctgctttgc tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt
    13921 gtactctgca acggcaacgt ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt
    13981 ttgcgttagc atccattcat aatcagtgaa aagatttttt actttctgca tcgcttcaga
    14041 tggcagattt ttctcgccat ctttccattt ttgccattgt tctggactga tcagcaagta
    14101 ttcatctaaa aaattttttt cagtttcaaa ctgttctaat aatacactca taataagatc
    14161 aatatatact tgatgcacgt ttatcccctc cttttaacta ttctacttaa gttttgatca
    14221 aaaagcacct cttaaatcgc tgctttcatt ttttttaatg tttcaagtcc tctcctcttt
    14281 attcttcgtg atttttgtta taataataga cagacaagaa actcaatcca actatgaagg
    14341 agcgttttca gatgaaaaaa tatcaatggg gaatcgttgg tcttggtacc atcgcacatg
    14401 agtttgccga aagcttcaat caagagacga gcgaactaac agcagttgct tccagaactt
    14461 cagaaaaagc ggaaaacttc gctcaccgtt acaatattcc aaaagcttac ggaagctatc
    14521 aagaaatgtt agacgatgct gaaatcgaca tcgtgtacat tgctgtacca aatagacagc
    14581 atatcgacca tatcttggca gcattggaag caggcaaaca cgttctatgt gaaaaagcca
    14641 tcacgatgaa taaaaaagaa ctggctgacg ctatgcgctt agcagaagaa aagaatttga
    14701 tcttagcaga agcgatgaca atcttcaaca tgccacttta tcagcagtta cgctcaataa
    14761 tggatacagg aaaactgggg gctttaaaaa tgatccaagc acctttcggc agttacaaag
    14821 aaccagaccc taaaaaccgg ttcttcaatc cagaattagc tggaggagct ctgttggata
    14881 tcggtacgta tgctgtatct ttcgctcgtt tctttttgag ctctcaacct gaagtagttg
    14941 cctctacaat ggttcctttt gaaacaggcg tggacgaaca atccgtcact atcttgcgta
    15001 acaaagaaaa tgaacttgct gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg
    15061 gtatcgttgc ctttgagaac ggttatgtga cgattgctga ttacccgcgt gctgatcgtg
    15121 cggagatctt atttacagat ggtacaaagg aattcatcga aagcgggaat acatctgaag
    15181 caatgaatta cgaaataaag aatatggtac acatgattga aggtgacttg cccaatcgct
    15241 ctctcttctt gacaaaagat gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa
    15301 atatgtaatt ttaaaaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    15361 acaaaaatag ctcctcctat ttttcgtttg gctggactta ttaccgcaga ggaaagcttt
    15421 tgaacaccgt ttaagaaaga ggttgtgagc ctaccgttca gctccgagtc acaaggagca
    15481 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttgac
    15541 aggagaacac cgtttaaaga agaggttgtg aaatcagctt tttgacctga atattagctg
    15601 aattcacaac ctctattttt ggattttttg ttgggagaat tctgccttga tttcaataaa
    15661 acttttaaaa gactgcaaaa actggaacaa ttctgctcga tcctcgaatt cagggcgact
    15721 agtcggcaga ggcatttgcc gatacaatac ataaacttct tcaatacgtg ttaaaatttg
    15781 tctgccatca tttgactctg aaaatgtttc tgcagtataa atcaataaac catagatatg
    15841 ttttccataa taagctggtt gctggattct ctctagattt tccagcatgt ctttaatcac
    15901 attggcctgt gctcttctca tagagaagta agtttcgtag tatagcggct gtctgagcca
    15961 gtagttttct tgatgttctc tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg
    16021 ttcgcatttg atctgcacat cttctttatt ttctgataaa agaaattctg ccatttgtct
    16081 caaaatattt cgaaattctt tttcgatctg tatttggttt tccttcagct gcttcgtacg
    16141 atctggcatg taaacatttg caagcaaagc aaatactaat ccaatcgcca ttaatcccgc
    16201 ttcattgccg atcagctgcc aagacatgtt ttcctccact aaataatgag tgaccaaaac
    16261 cgaatttact actatccctt cggttaattt gaagcgagag gcaagcggga tgaacaggaa
    16321 taaaaaaaga ctgaagccaa aaatagtata cccaacagca aaaaaactga acagtgctgt
    16381 tgccgtagct aatataaagg ctgcgattcg attcatgccc gtacgcaatg tagagcgctt
    16441 ggtatttcct acacttaata atgcaatgat ccctgcagct ggccaataca acagcgataa
    16501 gctacccgct gtgaccatcg aaaagaagac actgatcact gttttgactg ttcgcattcc
    16561 tatacgcatt tacttccccc ttttttattt taattatact tgaataatga aaaactagct
    16621 atcagacaaa agtttaggta tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt
    16681 tggccgtttt cgactaggta tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat
    16741 cttgtttttt catttgactc aacgaggaat cccgatgatt gctgcattat ctgctgtttt
    16801 ttctttgcgt caggacttga ctacaaccgt ttcttttgga aagtctagga tcatcggcaa
    16861 tacattaggt ggtacattag ctatcattta tttttttgtc aaaagctatt ttcacaatga
    16921 ttttttggta gaattgatct tgcttcctat tctagttatt attgtgatcg tcgtgtcaga
    16981 tggtattaac aataattccg gtatcatttc cgcaatagct acgttgttgc tgattgcgtt
    17041 gagcatccct caaggcgaat ccgctttgta tgctatccaa cgtgtactag atacttttat
    17101 agggacattc attgcaatcg gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa
    17161 ggaagaacta tcagaagatt tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa
    17221 tttacaagag atagaagcta agatccaaaa acaaaagaaa aatagcgagg actaattttc
    17281 ttttgcaata aaataaaaaa atggagagaa gaactttaaa aagtcttcct ccatttttga
    17341 ttgaacggtg aagtgtacta ctttattctt ccttcatcga gttttgttct gcctcttttg
    17401 gcgcttcata catatttact tggctagtag tcccacgtgt cgacaaattc tctacgattt
    17461 ccttcaagtc aagtcctgtt gtcgctttta gtgtttcttg agtagaagaa agcaaatttg
    17521 tggcataatt tgtcactcgg ttcgctccac tggtttctcc tgaactgctt cctgtatcga
    17581 caacagagat tttttcgata tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta
    17641 gcatatcgat aaccatactc aagacagctg cttcgccata ttccttgaag gcattggcga
    17701 tcttttgttt tgcttcggct tctgcttttc cttttgctag tgctgcttcg gcttctgctt
    17761 gtccagctaa acgtgtctta ttggcttccg cttctgccag tgcttccaca cggaatcgtt
    17821 ctgcttcggc ttcagtcact tctttgactt tttgagcttg tgcttcttgt tctttagcgt
    17881 accgatcggc atctgctttt ttcttcactt ccgaatcata ttgcttttca cgacgtgtga
    17941 tttctttttc ttccagttcg atttgttttt gacgttctac gattttaatc tgcatttcct
    18001 gttcgattac ttgttgttgt gctcgggcac tttctaaatt gtaggcttgg tctgcttttg
    18061 ctttagcaac atcttgttct tgtttgtagg ttgctaattt cagttctttt tcttttaatg
    18121 attctgcgat ctctgtttgt cgctgtaatt cagctgcttg tgattctttt tctgcttgag
    18181 cttttttgat acgcgtttct tttagagctt ccgcttctgc tatatctgca tctcttttga
    18241 cttgggcgat tcttggtttc cctaaagagt caagataacc gtttttgtct ctgacctctt
    18301 tgatagtgaa agaaacgatg atcaacccca tttttgcaag gtctacagaa gcgacttctt
    18361 gtacgctttg actgaactta tcgcgatttt gatagatttc ttctacagtc atagaaccaa
    18421 gaatcgagcg caagtgtcct tctaatactt ctcttgcttc attttccagt tcttctcttg
    18481 tcttgcctaa aaactgttct gctgctgtag caatctcttc tacagatgaa ccgattttga
    18541 tgatcgaagt accatcacac atcaccggta cgccttgttc cgtatacact tcaggggtgg
    18601 agacgtccaa tttactcgat aatagactga tccgattcga acgttgaaaa actggcaaga
    18661 cgaatgcgcc acctccacgc acaattttga ttttgttatt gctttcatca atgtgcacat
    18721 ttttgcttcc taaataactt ccactgatga tcaacgcttc atccggtttt gctgtctggt
    18781 acttcgctac aaagacgatc agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga
    18841 taaaaacaac tggtatttcc atttaacaca cgctccttta agcttttatc atgctttcat
    18901 aaggcatgac ataacagatt ctttccttga tctcaatgat caatactttc gttccccgct
    18961 cagctgtctg ttcttggggg ctgtaaaaac aagctggacg actaatggaa ccggtaacac
    19021 ttttcaactg aatttctccc atacctcgta cagggatcgg tgtgatcaca acagctactt
    19081 gtccttccag agttttttca gaagacgaca tcgttgattc ggcatgtttc atcggcatca
    19141 atatatagaa attaagcaaa aataccaaca ctatcgatat gcctccacta gcaataaata
    19201 aaaataaaga tgattgatct gttaaacgct cacctagaaa accaaataag cttgtgaaag
    19261 ttaaccaagg gataataagc atcggatcaa gcgggccatc aaaatcgaat acatctccaa
    19321 aaataatcaa taggactgcc aatcctgcac aaatcagcaa tgtataccaa taaatcgtct
    19381 caagtgcgat tccccctatc atatacacgc ctccttccat ttctacgtct atcataccaa
    19441 tgtttgaaaa ttctgtatag cttcttttac cgactcagtg gtgtttttta taggaaggtt
    19501 gtgtttatcg ttgacaattt gttaaatttt tgttttcatg ttaaaatttt cacaataaat
    19561 tctttcgagg tagcctatgt ttcctttttt taagaaaaaa ccattaaagc tccagaacac
    19621 gatcatcctt gtcgtttgtt tctccacatt cgtttctttg attgtttctg ccatattgat
    19681 caggaatttt attctttcga tgaaccgatc tagtgtgtca gataaaatct ctagcattgc
    19741 taaaatcgtt gccaatgata aactcatcca aaaaaagctg cagactggtg acccgacaca
    19801 tgcgattcaa ggaataacaa atgaaatcat gattgcatcg aatttagatt ttatcgttgt
    19861 catggaccct gaaggcattc gatattctca cgcagaccca agttacatcg gtcttccttt
    19921 ctcaagtcat gaagatgtga aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga
    19981 aggaatgtta gggttcggct tccgctattt cgtccctatt tattatgatc aagagattat
    20041 tggtgcagtt tgtgttggct taacaaacaa cacgattgac aatcaagtca aagatggaca
    20101 aaaaatgatt gttttttcat tgattattgg acttagcgta ggcatcatag gcgccgtttt
    20161 tcttgcccaa aaaatgaaaa aagtactgct tggacttgaa ccacaagaaa tagcagaaca
    20221 gttaagtgaa aaaacgatta tcgaaaatga agtagatgaa ggaatcttag ccatctcttc
    20281 tgataaaact atcctcttga tcaatacacc tgcaaaaaac attttctacc aaacagagca
    20341 gctattggat ttcgaagtag gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa
    20401 gagacgattg agcatcaaac gaccgttcgg actcaatcca tgtatttaaa tgggatagaa
    20461 actatttcta gcgttacacc tctttttagc aatgaccgtt ttttaggagc agtcgcaact
    20521 ttacgaaatc gatcagaagt aatgaaatta atggaggagc ttggggggac gaaacaatat
    20581 ataaactcca tgagagctca aacccatgaa ttcatgaata aacttcatgt catttctggt
    20641 ttgattgatt tgaagaagta tgaagaagtc acccatttta tccagcagct aaatcaaaat
    20701 tataaaaaag agattggcca agtctcaagt ctgatcaaag tacctgcaat tgccggtttt
    20761 ttattaggca aaataaacga agccaaagaa caatctgttg aaatgctgtt agaaagcgat
    20821 tcttttatcc ctaaaatgga gatggatgac tccatccatt cacttttgca agtgttaggg
    20881 aacttacttg ataatgcaaa agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc
    20941 cggattcatt taaactatga cacagaagct gaagtattca tcgtgaccgt ctgcgatgac
    21001 ggtgtcggga tatcagaaga aatctcagaa aaaatattta cgctaggttt ttcgacgaag
    21061 ggaatcaatc gtgggtttgg attgaatctc atccattcaa tcgtcaaacg ccacggtgga
    21121 tttttagaat tttccaaaca aacaaatggc ggtacaatcg tctatctaga attaccaaaa
    21181 aaggaagatc aaaatgatga caaatgtcct gataatcgaa gatgatccaa tggttgcaga
    21241 attgaatcgt acttttgtgg aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa
    21301 tgtagaagaa ggaaaaaaat atttcagaca aaaaaacgca gatctgctgc tgcttgatgt
    21361 atacatgcct ggcgaaagtg gtatccattt tttatcttgg cttagacagc aaggaaatga
    21421 tatcccagtg attttgatca ctgctgcaga tgatatcgaa accataaaga atgtgatccg
    21481 ctacggtgcc ttagattatt tgatcaaacc gttcactttg caacgttttc agctggcgat
    21541 cgaaaagtat cttgctttct ctcagacaat ccaaacgact gaaaaagccg atcagaaatt
    21601 gatcgatcaa gtattcaacc acaccactcc cattcacgaa ataccatcat tcatcgattt
    21661 gcctaaaggt ctgtcaaaac tgactttaaa aaaaataagt gcatttattc taaaagaaga
    21721 tactattttt tcaacaaaag aactggctca aaaaagctca ctgtcacgta tatccgtcaa
    21781 gaaatatttg aattttttag tagaacaaga tatattgaac gaaagaatca aatatttgga
    21841 aatcggccgg ccgctaacct gttatgaatt gacaaagaat gggcggaaaa agctcacaga
    21901 ttactgttga gtcatcgaat tatcccatac aaaatagtcc aagtatacag aagtaacaac
    21961 tgtttacttg gactattttt aaacatttta ttgacgaata tccatgtttt cttatcttaa
    22021 ttgacgggct ttaggaagag atacctcatt tttcgttttt ccagtttcta ttatttcacg
    22081 aaagttctcg aaacttgtcg aaatcatatt tgataatgcc tcatctgtat ttgaacctac
    22141 atgcggggtt acaagaactc tagggtacat ttctactaat tgctggatag cagggtctgg
    22201 aatcgtctcc catggcttga aggatcggaa aaaaacctct gtttcatttg caaaaacatc
    22261 ggttgcaaaa ccagctaaat gattgctttt caaagctctt aaaatagctt cattatcttg
    22321 aagctctcca cgggctgtat taatcaagat gctacctttt ttcatttgag ctaaaaatcc
    22381 ttcattgatc atttgatcgt tttcacctgg gatatgaggt acatgaatac tgacaatatc
    22441 gcttttggct aataactctt caagcgagtg gaacgtcaat acttttttag cagcttctgt
    22501 ctgatgaata tcgtagccga tcactttggc tcctagtccc ttaaacaaaa cagcttccgt
    22561 caaccctatc ctgcctgttc ctatgatccc tactgtgcaa tttctgattt cacgactaaa
    22621 catttgctca tccactcgaa aatctttgaa agatgttcgg atcgtcgtat acgcagtatt
    22681 tctcaaaagc atcatggcaa aagtcaaaga taactctgct atcgcatttg gcgaatacga
    22741 tggtacacgg gctactgtca taccaaaatc agctgccgct tgtagatcga tatgattgac
    22801 tcccacagtc cgtgtaaaaa cataacgaat cccatattcc tgcatttttg caagattggt
    22861 ctcatctgct atacaatttc ccctcaacaa tacagcatca tggtcctttg ctgacacgat
    22921 attgtcatgt gtcaacagtt cttcataaag actgagatca taatggtaaa tattcaattt
    22981 ttcaaaaaaa tctatctcgt tcggacgaac accgtaacat gcgattctca tactttcttc
    23041 ctccatttct tatgaaaata aacctatgcc atgaatcatt tgtaatacaa cgatccatac
    23101 aggtgtcagt accacagcaa aaatagttga cagtaaggat gcattggagg ctaaaagtgc
    23161 ctccctatca aaactgatag cataggctgc tgccactgtt gcagctggtg tagccatcat
    23221 gataacgatt gttgccagtg cttcaaaatt gactggtaga atattcgttg ccgtcaaaac
    23281 tgctagaatc acgatattca atgcaggtac aaataccact ttgactagac tgtaatacca
    23341 tgaagttttt tcagatgcag cttttttgaa gcttacttca cctaatgttg cgccgattgc
    23401 tagccacgcc aatggtgaac ttaaaccagc taaataatcc atcggctgaa atagccacgg
    23461 tgcagtctgg tcaattcgca aaaacgctac ttggcttatc tctccttctg cacctgtaac
    23521 tgacacttgt ggcagatacc cttggaacag ccaaatgaaa aggccggcaa aagtagcgat
    23581 aatgattgga ttgacgaaca tcgctttgat atttttagct tccatcttca agccactcat
    23641 ttttatgtat ccataagaat acaaaaagat tcggtagcca atattgaaaa ttgaggaata
    23701 catcacgccg acaggaccat aaatcgcact gacgataggc gttccgaaaa aggtcgtaga
    23761 accaaagatc gtcaggacac gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa
    23821 aggttttgaa actagaataa gaataatata aataactaat ccccaaatca agacattgat
    23881 tccttgcatc agtaattctg tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg
    23941 caaagccact gttaagacga ctttcgatag aatttttcca acagattcag aa
//
LOCUS       DAZAOD010000031        23669 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000031 DAZAOD010000000
VERSION     DAZAOD010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.032"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..120)
                     /locus_tag="ACHDPO_001304"
     CDS             complement(1..120)
                     /locus_tag="ACHDPO_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFN3368943.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            299..1960
                     /locus_tag="ACHDPO_001305"
     CDS             299..1960
                     /locus_tag="ACHDPO_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFN3368944.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2392)
                     /locus_tag="ACHDPO_001306"
     CDS             complement(2030..2392)
                     /locus_tag="ACHDPO_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFN3368945.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2460..3401
                     /gene="opp3b"
                     /locus_tag="ACHDPO_001307"
     CDS             2460..3401
                     /gene="opp3b"
                     /locus_tag="ACHDPO_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFN3368946.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3402..4445
                     /locus_tag="ACHDPO_001308"
     CDS             3402..4445
                     /locus_tag="ACHDPO_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3368947.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4451..5521
                     /locus_tag="ACHDPO_001309"
     CDS             4451..5521
                     /locus_tag="ACHDPO_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368948.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5511..6464
                     /locus_tag="ACHDPO_001310"
     CDS             5511..6464
                     /locus_tag="ACHDPO_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368949.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6476..7486
                     /locus_tag="ACHDPO_001311"
     CDS             6476..7486
                     /locus_tag="ACHDPO_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFN3368950.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7771..8592)
                     /locus_tag="ACHDPO_001312"
     CDS             complement(7771..8592)
                     /locus_tag="ACHDPO_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFN3368951.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8689..8967)
                     /locus_tag="ACHDPO_001313"
     CDS             complement(8689..8967)
                     /locus_tag="ACHDPO_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368952.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9235..11244
                     /gene="metG"
                     /locus_tag="ACHDPO_001314"
     CDS             9235..11244
                     /gene="metG"
                     /locus_tag="ACHDPO_001314"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFN3368953.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11723..12310)
                     /locus_tag="ACHDPO_001315"
     CDS             complement(11723..12310)
                     /locus_tag="ACHDPO_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368954.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12485..13807
                     /locus_tag="ACHDPO_001316"
     CDS             12485..13807
                     /locus_tag="ACHDPO_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFN3368955.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13962..14738
                     /locus_tag="ACHDPO_001317"
     CDS             13962..14738
                     /locus_tag="ACHDPO_001317"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFN3368956.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14731..15300
                     /gene="rnmV"
                     /locus_tag="ACHDPO_001318"
     CDS             14731..15300
                     /gene="rnmV"
                     /locus_tag="ACHDPO_001318"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFN3368957.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15293..16177
                     /gene="rsmA"
                     /locus_tag="ACHDPO_001319"
     CDS             15293..16177
                     /gene="rsmA"
                     /locus_tag="ACHDPO_001319"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFN3368958.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16628..17257
                     /locus_tag="ACHDPO_001320"
     CDS             16628..17257
                     /locus_tag="ACHDPO_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368959.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17381..18490)
                     /locus_tag="ACHDPO_001321"
     CDS             complement(17381..18490)
                     /locus_tag="ACHDPO_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368960.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18699..19121
                     /gene="mgsA"
                     /locus_tag="ACHDPO_001322"
     CDS             18699..19121
                     /gene="mgsA"
                     /locus_tag="ACHDPO_001322"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFN3368961.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19308..19406
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19444..19980
                     /locus_tag="ACHDPO_001323"
     CDS             19444..19980
                     /locus_tag="ACHDPO_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFN3368962.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20020..21783)
                     /locus_tag="ACHDPO_001324"
     CDS             complement(20020..21783)
                     /locus_tag="ACHDPO_001324"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368963.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21786..23501)
                     /locus_tag="ACHDPO_001325"
     CDS             complement(21786..23501)
                     /locus_tag="ACHDPO_001325"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3368964.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7635 a         4322 c         4801 g         6911 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt tttcatttga ttgctccttt atttttggtt
     2401 cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg gaaacattag
     2461 tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc acgctttggt
     2521 taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca tatacgaatc
     2581 aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt ttggataaac
     2641 cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat tttggaattt
     2701 ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc ggaccatcct
     2761 tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt ttaggaacga
     2821 tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta gcgatattag
     2881 gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt gcaatcaaat
     2941 tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta ccaacaattg
     3001 cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa atggtggaag
     3061 tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt tgggaaatcg
     3121 cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta ggaccgttag
     3181 ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt cctggtatcg
     3241 gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg gctgtaacga
     3301 tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg tacggtctag
     3361 ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg ataccaaagc
     3421 gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa aaaaataccg
     3481 aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat tcatggcgcc
     3541 gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc atcattttga
     3601 tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac gtggcttata
     3661 tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga aaagcaatgg
     3721 ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac gtaaatttct
     3781 ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg ggaatgagaa
     3841 tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt gtagcttacg
     3901 ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa
     3961 tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt tttgaaccag
     4021 gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg gcacgtatcg
     4081 ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga ttgacattag
     4141 gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct agtgtcatta
     4201 ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt ttaagcttta
     4261 tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc gaagggtaca
     4321 agacattcct gtatctgcct tatctattat ggattccggc agtaacttta tcggttatca
     4381 tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag
     4441 agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt ttgatacgta
     4501 tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag gagaaacatt
     4561 ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca tcatgcgctt
     4621 gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta acgatatcgt
     4681 tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca
     4741 agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg ctgagtccct
     4801 tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag aattgcttaa
     4861 attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc agttctcagg
     4921 aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg aaatcctgat
     4981 tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt tggagctgct
     5041 gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg accttggtgt
     5101 agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg
     5161 aacatcggaa gaaattttct acaacccgca acatccctat acttggggac tgcttggttc
     5221 aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt ctccaccgga
     5281 tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg cgatgaaaat
     5341 cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg cagcaacttg
     5401 gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac gtcgctgggc
     5461 tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg atgccaaata
     5521 aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac
     5581 atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt ttagttggag
     5641 aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat gaacctactg
     5701 atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa aaaggtttga
     5761 cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg ttgaatcctc
     5821 gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta gctaaatcat
     5881 ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg aatccaagcc
     5941 acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt ggtattgcac
     6001 gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct gcactagatg
     6061 tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa catcaattga
     6121 cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac cgaatcggtg
     6181 taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat aatcacggtg
     6241 ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca gaccatgaga
     6301 gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta cgtcaacttc
     6361 gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca tattacgcaa
     6421 aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga catagatgct
     6481 aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat tgattcgtac
     6541 ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga aaagttggca
     6601 acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag aatacccatt
     6661 cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg atcgggcttt
     6721 tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg
     6781 gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg gctacttaaa
     6841 gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg aaggatcgat
     6901 tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac tactttgtga
     6961 tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct atcatccgaa
     7021 gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc accagacaga
     7081 agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag
     7141 aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag taatggatct
     7201 ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg ggaaattggt
     7261 caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac atgctgattt
     7321 ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc aatggtataa
     7381 taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg taagaaagag
     7441 ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa tgaatgaaac
     7501 tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt tgtttctagg
     7561 aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca atagcagaaa
     7621 aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt tacgaataca
     7681 tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt ttttcttgaa
     7741 tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct tgagctgata
     7801 gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga aatattggag
     7861 catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta agaatttagc
     7921 aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta gaacttgcgg
     7981 ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt gactatggtc
     8041 aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg agatagccac
     8101 ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc agcgtacttc
     8161 cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt agctgactgt
     8221 gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt gctcaatatt
     8281 ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc tttctccagt
     8341 tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat aaggatgccc
     8401 ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc acatcagtac
     8461 gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt gataccagtt
     8521 aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt ctttagaagc
     8581 aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct tattgtagca
     8641 gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt aaatatgaaa
     8701 aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca atactttata
     8761 ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa tgataaaacg
     8821 caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa aataaccata
     8881 catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag caatactaag
     8941 tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag atagatagtc
     9001 tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga tatgaaacaa
     9061 aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt gaacgtagat
     9121 agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg ctttttttat
     9181 ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag ccccgtggca
     9241 gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa acttcatatc
     9301 ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg gttgatgggc
     9361 tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga aacaaaagca
     9421 gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga tgtcaagaaa
     9481 ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga tgattaccat
     9541 aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat ttacttaggt
     9601 gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac acaacttgca
     9661 gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag tggacacgaa
     9721 gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc agaccgtcta
     9781 ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa aaacgaaatg
     9841 atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac aacttttact
     9901 tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat cgatgcatta
     9961 tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt cgaaaaatac
    10021 tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac gatctattgg
    10081 ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg gcatggctgg
    10141 ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg
    10201 cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc tgttccgttt
    10261 gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta tgatctggca
    10321 aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata ttgtgatgga
    10381 ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc tacgacggct
    10441 gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa tacagcattg
    10501 gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac agaaccatgg
    10561 gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat ccatttagct
    10621 gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac gccagagaag
    10681 atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt acactttggc
    10741 gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc acgtttagat
    10801 atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca aacaaacgaa
    10861 gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga aaaacaaatc
    10921 aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa
    10981 gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag ccaagaccgt
    11041 caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat cgggaaaaaa
    11101 gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg
    11161 atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc aaaatccatg
    11221 ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt tgtgtcatac
    11281 cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta cttgaagcca
    11341 atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag aagtacgagc
    11401 ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac agaaaaaaag
    11461 cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt ttttattgtc
    11521 cttacattca taaagtttga atgcaatgac tttattacat ctatatttat atctaacagt
    11581 agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt gtgctcttat
    11641 atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg atgattgttt
    11701 tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt tttgtcttca
    11761 aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca taccagaaaa
    11821 tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt aacaagatca
    11881 accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg acttcactaa
    11941 gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc atccgccagt
    12001 tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag
    12061 gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc acaggacctt
    12121 tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt gataacgttg
    12181 caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt
    12241 ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga taagaacgct
    12301 taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa
    12361 aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa aaagaatggt
    12421 aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa gaaagaggat
    12481 gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag ctaccgttat
    12541 gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg ctagtactca
    12601 gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga tctgtgctgg
    12661 attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg taaaatatat
    12721 tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa gcttgattta
    12781 ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga cgaacttatt
    12841 acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt ctgtgacagg
    12901 gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa
    12961 attaatacca attgctgtga ttgtcatatg gggattattg accccaggac aaggaactgt
    13021 ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc
    13081 gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa tggcagggga
    13141 aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga gttttgtaac
    13201 agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg atcatcttgc
    13261 cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa
    13321 gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt atacactaac
    13381 tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca gtaaacagct
    13441 gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc agttagcagt
    13501 agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt tgatttttgt
    13561 gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa aaaaagcgcc
    13621 ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta ttgcgattct
    13681 cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag cattgatcgg
    13741 tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga
    13801 agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct agatcttcgt
    13861 gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact tctgcaagta
    13921 gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt gattctcata
    13981 cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag cgagcacaag
    14041 aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt
    14101 tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat ccgacagagg
    14161 ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact ttaccaaagg
    14221 ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg aaagaagtcc
    14281 aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta ccaatcagta
    14341 ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa gatgttcgag
    14401 atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa cgatttcttg
    14461 acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc
    14521 aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat gccccttatc
    14581 tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt tatacagtag
    14641 aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa acatggacaa
    14701 atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca agagattata
    14761 gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc agatacgata
    14821 gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca tgcccaagag
    14881 actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat aagaaaaatc
    14941 attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca agctaaacca
    15001 aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt agaagcattg
    15061 aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac tagacaagac
    15121 cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga aaaactaggt
    15181 gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt gaagatgttt
    15241 cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca acatgagtga
    15301 atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac atggtttttc
    15361 atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa ggaaaatcgt
    15421 agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc
    15481 attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg
    15541 tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta ttgtacatca
    15601 agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg aggagcttcc
    15661 gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga tgcattttct
    15721 tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag tagctgatcg
    15781 tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg ttcaatatta
    15841 tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc agccaaatgt
    15901 agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag tgacagacga
    15961 aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa cgctttggaa
    16021 taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag caaaaagctt
    16081 ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac aagaattcgc
    16141 cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt
    16201 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatgt
    16261 ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    16321 ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa acagcttctc
    16381 atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact attatgccga
    16441 acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat
    16501 tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat gtgtcttgac
    16561 agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat attaggagag
    16621 agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat tgattgggat
    16681 gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt cctttacttt
    16741 ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg cagtggctgt
    16801 tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg cattgcgagc
    16861 attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc atccgagtat
    16921 cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt tcaattttgt
    16981 gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt actttattgg
    17041 taatatgcct gaaacatatt attctcaagg atatttttat acagtattca tcttgatggg
    17101 gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta tagcaggaac
    17161 actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa atcggaaaga
    17221 gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca aaaaaaaaac
    17281 tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc taaaaagagc
    17341 tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt ttgatgactt
    17401 gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg tcgactattt
    17461 cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta gaaccagttt
    17521 ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct gatttcacta
    17581 cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct ggacgaatac
    17641 cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt tttccttcag
    17701 gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat gtcacattaa
    17761 agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg ggtgtatcat
    17821 aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata acgattcggt
    17881 cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt gtttcaagac
    17941 gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca tctaaatttg
    18001 ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt cccaatgcca
    18061 cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat tctgtcagac
    18121 ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca tatttacgta
    18181 atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt
    18241 ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact tttccgccga
    18301 tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa gtagttgact
    18361 ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt gatagattaa
    18421 aatcagttac agaataattt tctgcattgt catatttttt atatacgttt ttcagagcca
    18481 tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt taaagtataa
    18541 atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt ttttttgtca
    18601 atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat acactggagt
    18661 aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc
    18721 atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca atattggaaa
    18781 aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca accggcttgc
    18841 cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga gccatgattt
    18901 cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca cagccccatg
    18961 aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg ttagctacga
    19021 atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta gattttcgaa
    19081 gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc gtatggaaaa
    19141 ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga taatatgcga
    19201 tataatacga acgtattgga taatataaac aataatatta gtttttcgta tttgcagtaa
    19261 atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac agagtagaaa
    19321 ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga cgtaatgttc
    19381 gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa ggagatgcta
    19441 aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt attgattgca
    19501 ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa aatcagtgtc
    19561 acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc agggataggc
    19621 gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt ctttattgga
    19681 tttacattga atgcatttat tgaaggagca atctacggat tctttttcta tcgaaaagag
    19741 atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat caacttattt
    19801 ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg ggtcgtttgg
    19861 gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc catttattac
    19921 gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca cgctaaataa
    19981 aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg tgaattgtgc
    20041 ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg tgcccatttc
    20101 gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg tggacaggcg
    20161 atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt gttggatttt
    20221 tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca tagggggatt
    20281 actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata tctttaaccc
    20341 ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt catacatata
    20401 agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc caaaacgaag
    20461 attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc caaaactttt
    20521 acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa ttgttccttt
    20581 tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg cccctgtttt
    20641 tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt cgatcaaacg
    20701 ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt tgatattttt
    20761 gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat cgatcaaatc
    20821 aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc cagaaagttc
    20881 gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca caccaacagt
    20941 gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg ataaataagc
    21001 aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt gtgcccgttg
    21061 tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag cttcttcttg
    21121 ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc ccgagatatc
    21181 cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa cgatccaact
    21241 cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg gacttagacg
    21301 catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt gattgaaggc
    21361 cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga cgatatttcc
    21421 gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa atgcatcttt
    21481 tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga tgagccattg
    21541 actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga acagtcgatt
    21601 gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt gtaacgtcat
    21661 cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa tgtcttttgc
    21721 ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt tttttacttt
    21781 cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga ttgagcaagt
    21841 aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa gatatgatgt
    21901 gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc aagataagtc
    21961 tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa agagtcatct
    22021 aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg ctgtttttgt
    22081 ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt tggaagctga
    22141 cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt ttctgtggcg
    22201 tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac agaagtttgg
    22261 ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac atccattccg
    22321 tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg tgtcaaagtc
    22381 gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt cagctgaaat
    22441 gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac atggtcaaaa
    22501 gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc aagaatcgaa
    22561 ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg tgtgaagatc
    22621 acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata attgatcaaa
    22681 gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc aactgtcagc
    22741 aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag ggcagagata
    22801 ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa cttctctgtt
    22861 tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt ctgactaacg
    22921 tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac ggtttttttg
    22981 atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa cagacctact
    23041 tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg tgctctgatc
    23101 aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt tgtcattcgg
    23161 gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt attgattttt
    23221 ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga agcatagtat
    23281 tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca taagcccatt
    23341 tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga agccatcatt
    23401 aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc caaaatgatt
    23461 tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct cctattattt
    23521 atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa tttagaatga
    23581 aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt agaaattgaa
    23641 tagactattt tttttaaaaa aaagaaaat
//
LOCUS       DAZAOD010000032        23663 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000032 DAZAOD010000000
VERSION     DAZAOD010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.033"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            70..480
                     /locus_tag="ACHDPO_001326"
     CDS             70..480
                     /locus_tag="ACHDPO_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFN3368965.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            473..1174
                     /locus_tag="ACHDPO_001327"
     CDS             473..1174
                     /locus_tag="ACHDPO_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFN3368966.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            1174..2760
                     /locus_tag="ACHDPO_001328"
     CDS             1174..2760
                     /locus_tag="ACHDPO_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3368967.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2779..3000
                     /locus_tag="ACHDPO_001329"
     CDS             2779..3000
                     /locus_tag="ACHDPO_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFN3368968.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            2997..3758
                     /locus_tag="ACHDPO_001330"
     CDS             2997..3758
                     /locus_tag="ACHDPO_001330"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFN3368969.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            4138..4647
                     /locus_tag="ACHDPO_001331"
     CDS             4138..4647
                     /locus_tag="ACHDPO_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFN3368970.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4722..5261)
                     /locus_tag="ACHDPO_001332"
     CDS             complement(4722..5261)
                     /locus_tag="ACHDPO_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFN3368971.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(5401..6012)
                     /gene="rpsD"
                     /locus_tag="ACHDPO_001333"
     CDS             complement(5401..6012)
                     /gene="rpsD"
                     /locus_tag="ACHDPO_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFN3368972.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            6274..7125
                     /locus_tag="ACHDPO_001334"
     CDS             6274..7125
                     /locus_tag="ACHDPO_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFN3368973.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            7153..7788
                     /locus_tag="ACHDPO_001335"
     CDS             7153..7788
                     /locus_tag="ACHDPO_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFN3368974.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7808..8581
                     /locus_tag="ACHDPO_001336"
     CDS             7808..8581
                     /locus_tag="ACHDPO_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFN3368975.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            8989..9786
                     /locus_tag="ACHDPO_001337"
     CDS             8989..9786
                     /locus_tag="ACHDPO_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFN3368976.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9764..10177
                     /locus_tag="ACHDPO_001338"
     CDS             9764..10177
                     /locus_tag="ACHDPO_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFN3368977.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            10161..12806
                     /gene="mutS"
                     /locus_tag="ACHDPO_001339"
     CDS             10161..12806
                     /gene="mutS"
                     /locus_tag="ACHDPO_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFN3368978.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12824..14932
                     /gene="mutL"
                     /locus_tag="ACHDPO_001340"
     CDS             12824..14932
                     /gene="mutL"
                     /locus_tag="ACHDPO_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFN3368979.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14954..15514
                     /locus_tag="ACHDPO_001341"
     CDS             14954..15514
                     /locus_tag="ACHDPO_001341"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFN3368980.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(15599..17587)
                     /gene="treP"
                     /locus_tag="ACHDPO_001342"
     CDS             complement(15599..17587)
                     /gene="treP"
                     /locus_tag="ACHDPO_001342"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFN3368981.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17810..18523
                     /gene="treR"
                     /locus_tag="ACHDPO_001343"
     CDS             17810..18523
                     /gene="treR"
                     /locus_tag="ACHDPO_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFN3368982.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            18600..19046
                     /gene="msrB"
                     /locus_tag="ACHDPO_001344"
     CDS             18600..19046
                     /gene="msrB"
                     /locus_tag="ACHDPO_001344"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFN3368983.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGVFKSLVE"
     gene            19216..19818
                     /gene="ruvA"
                     /locus_tag="ACHDPO_001345"
     CDS             19216..19818
                     /gene="ruvA"
                     /locus_tag="ACHDPO_001345"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFN3368984.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19831..20832
                     /gene="ruvB"
                     /locus_tag="ACHDPO_001346"
     CDS             19831..20832
                     /gene="ruvB"
                     /locus_tag="ACHDPO_001346"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFN3368985.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20861..21439
                     /locus_tag="ACHDPO_001347"
     CDS             20861..21439
                     /locus_tag="ACHDPO_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3368986.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            21491..21973
                     /locus_tag="ACHDPO_001348"
     CDS             21491..21973
                     /locus_tag="ACHDPO_001348"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFN3368987.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            22090..22464
                     /locus_tag="ACHDPO_001349"
     CDS             22090..22464
                     /locus_tag="ACHDPO_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368988.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            22894..>23663
                     /locus_tag="ACHDPO_001350"
     CDS             22894..>23663
                     /locus_tag="ACHDPO_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HFN3368989.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRN"
BASE COUNT         7734 a         4232 c         5079 g         6618 t
ORIGIN      
        1 agcatgtttt gaaactttca gaaaaggttt gttagtaaaa tgaaagctat acgtaaggag
       61 tgttgtttga tgaaattttt tcaagagttt ttcattatta ttttcttttc tgtattagga
      121 gaaggcatac ggatttttgc tcatttacct attcctggaa gtatcttagg tattcttttt
      181 ttatttttag catttgaaat gcatcttgtt gatcctgaaa aaatcggagc aactggtgat
      241 tttttattga ataatctagc cattttattt gttcctgctg gtgtaggttt attggaatat
      301 tttgatgata ttgcttcgat atggcctgtt ttactgggag cagtcgtcgt gtgttccatc
      361 gtcacgatgg ttgcagcggg aaaaacggca gaaggtgtag aagctttgct gggctatgtc
      421 cgtaagaaaa aagcagaaag ggtatctgta aacgaaatgg aggagaatca aattgactga
      481 gttttttgtg aatccattat ttggcttaag tttgacttta ggagtgtacg tattatctga
      541 caaatttttg cggaaatata aactgcctgt tttgaatcct ctcgtattat cgattgttgt
      601 tattatctta tttttgcatt tttctgggat cagctataaa gactataata tcgggggcaa
      661 ttttttgact atgctgatta ctcctgcgac agtggcactt gccatccctc tttataaaaa
      721 cttccgttta ctgaaagaga atttttatcc tgtaatggct gcgattttag caggaatagt
      781 cgcaaattgc ttggttagtg tagggttcgg ttacttcttc tctcttcata aagagatggt
      841 gatctcatta ctacctaaat ctgtaacgac ggctatttct gtcgatttat ctcatacgat
      901 gggcggggtg aatgccgtga cacttgctat tgttgtctct acaggtattt ttggttcgct
      961 gatcgccact catattttcc gcctattcaa gatcgaaagt ccagttgctc gcggtgtggc
     1021 gttaggaagt acttctcatg ctattggtac agcaaaagca atcgagattg gtgaaataga
     1081 aggaatcatt tccggacttg cgatatgcgt caacggaata ttgaccgttt tattgctacc
     1141 gttattcttt cagccttttg ctggcttgtt ttgatgcgaa aaccactatt ttatgctaca
     1201 ataaccaaaa cgttcgagca taaaaaagga gggaaagacg tgtatttgtc ttccgagtat
     1261 cttaaacaat ttgataaaga tctatattat aagattctcc tcctagaaag ttttgaggat
     1321 caagcttggc ataccgctgc acaattagcg caagttgttc agctggatgc ccgcagcgtg
     1381 tcgaaatacc tgaacgagct gtctaaaaac tatcagcagt ttagcggtaa gacacaccct
     1441 ttgtttacaa aaaatcaccg ttctggttat aacttttatg atacgctcga ttcaattgaa
     1501 catgagcgtt ttttgatcta tctcgtgcaa agtacgctga aattccagtt gctgcacgac
     1561 attttttttg aagaattcca tacaatgtac caatttgcgc aaaagcatta cattagtgaa
     1621 tctactgctc atcgaaaaat caatgaatgg aaacagcaac tgcaaactta cggaattcgg
     1681 ctgcaacgag gtacatatat cgctcaaggc gaagaagaaa tcattcgact ttacttgcat
     1741 atgacattct ggcagttgtt tcgagggaaa atctggccat ttgaaacgat ttctcaaatg
     1801 gacgtaaaga atatggcaga acatatcatg gcttttttta atgttcgtct gaacgagatc
     1861 aaaaaaagac gattggaata tatgctaggt gccttttttt taagaaaatc acagaagcat
     1921 tatgttgtat tgaatgagaa aaaaagacgg ctgatttctg acaatctgtt gttccagcga
     1981 ttttgccagg tcatggagcc ggtatttcct aattattttc aagtagaaga cgagttaggc
     2041 gcattatttc ttgtactgat gactcgtgaa gaatattata gtgatcctaa gatacggaag
     2101 aaaatttttg attttcatca acaagcaaaa acaccgccct ttacagccct ttcagaagca
     2161 aaagccgctc tttctcttta tcaggaagag caggggctgc cagcagaaaa tctaaccttc
     2221 gaggcagaaa actatttatt cagcagtcat tttttcgcct atctttttcc taatgcgaaa
     2281 gaaacgattg atggcaatag tagtgatttt attaatcatt tagttattga aaacaaggaa
     2341 ttgaaacaat ggctcgtaca tttttttgaa agtagacaca aacatcccaa tcatctggca
     2401 tttaaaaatc atgcgttttt gatggggcgg tatctgactg tgtttaaaac attaggagcc
     2461 tttactccac agcttccaaa gatcacgatc cttttaatga cagatttccc attatttgaa
     2521 gagcaactgt tagaggaggg attacggaca tttttccgta atgagtatca gctgattttt
     2581 ctgccaacag attatcgggg gagagaagtt gatcttctga tttcgacaag taaagtccac
     2641 cgcaaaccat gggcggatct tgactatttt attgtgactg aagaactaaa attaattgat
     2701 tacatccaac tatctcaaaa atttgaaatg attcaaaaac aaaaactatt aaaacaataa
     2761 caaagaagga gaaaaaagat gacatttgaa gaaattttac cagaattgaa aaaaggtgca
     2821 aagattattc gtaaaggatg gagtggattt gaactttatg ttgttctcgt atccgatgat
     2881 gaatttgatg gctgtccggt gacgccgtac ttattgatca aaacaagtga cgaaggtttt
     2941 tccagcttcg ctcctacagt ttgtgatatt ttagcagatg attgggcgat cgtagaatga
     3001 aaaaccagta tccagatcta gctaaacagg ttgtatttat cacaggagct gcttctggaa
     3061 ttggtgctgc gcaagcccga gcgtttcttg aacaagatgc ttttgtattt ggattagatc
     3121 aaaagttcgg taaaatggaa gaaatttctt tgcgatttcc tgaaactttt gcctacgcac
     3181 taggtgatgt tcgacaaatg aaagaactcc aacaagcggt atcgaaatgc caaaatcatt
     3241 ttggtgaagt tacgatttta ctgaatacag cggggatatt ggatgcctac aaacccttga
     3301 tggaaactga cgaatcgctg tgggatctga tttatgagac gaatgtgaaa agcatgtatc
     3361 agctgacaaa aatcatcctt cctgatatga tccgccaaaa aagcggaacg atcatcaata
     3421 tggcttcgat tgctggcttg attgctggtg gaggtgggat cgcttataca agcgcgaaac
     3481 atgcgattgt cggatttacc aaacaactcg ctctggatta cgcaggacag ggtatccgag
     3541 taaaaggaat tgctccagga gccatccaaa caccaatgaa tgcggctgat tttgaaggga
     3601 aaggtgagat ggcagagtgg gtggcaaatg aaacaccagt caagcgatgg gcacagccgg
     3661 aagaagtagc tgagctgacg ttatttcttg cctctcctca agcaagctac atacaaggaa
     3721 cgatcatccc aatcgacggc ggatggttgt taaaataacc ttgtgttttt ttcaagcttc
     3781 tgtatgataa aactaaagag agaaacaacg gttgatgata aaaaaagtcg atgactgttc
     3841 ccgacattcg atgccgaaca gccagttcaa aaaattcttt ttaataatcg ttaatattcg
     3901 aaactaagcg gcttttcacg acctcttgat ataaacgata ttcaaaagct tgcaactgcg
     3961 gtaacaagtc cagccaaatg aaaaatataa ggagctattt ttatttgacc attcttatta
     4021 cttgttgcag ggcagctttt tcactacctt ctgcgacact tcagttggaa ttttcttccc
     4081 atcctttggt cgcggtcatt accaagataa aattatcttg caaaggagaa atagaacatg
     4141 gaaaaaaata atacccgttc agccaaacgc tggacaacga cagatgtgac tcggatggcg
     4201 ctagtcactg gtttatatgt ggcagtgacg ctggttttgt ctgtctttag ctttggagtg
     4261 attcagattc gtctctcgga gatgttcaac tatctgtcct tgtataacaa aagatacatc
     4321 gtcgcggtaa cagcgggagt agctttggct aatattgctt ctcctcttgg actgatagat
     4381 gttgcagtag gaagcgtcag cacgctgctt gtattgctta tcaactataa aatcactagt
     4441 cgcatcaaaa acatgaaaat caaaatggcc gtgacagcat gcgtatttgc tttttccatg
     4501 tttacagtag ctggtcagct aacgatttta tatcaactac cttttttctt gaattggtgg
     4561 gtgattgctt taggagaatt ggcatcaatg attgtcggtg ggataattat ttattggatc
     4621 ggtaaaaaag tggatttgtc aaaataaaga tctgtttaat ttaaaatagg gcagcatgga
     4681 agagactgaa tgttgagtct tcttccatgc tgcttttttg attaatttgt atgaagaaat
     4741 cgatttagcc gttttttcat caagataccg atataagctg ctccagttgc cttgattgct
     4801 tccggcagta aaaacggcag tagtccactg gcaaatgcag ttgtaaaagt aagatcacca
     4861 cttattttca gccagatcgt tccgcagatc aatgcagcaa gagagcccat tagattggca
     4921 aagattgcat ataagtaatg agcatccgtt ctttcgatca tccaaccagt tatccacgtt
     4981 tgtaagagaa atccaatcaa atatccgcca gttggcccaa ataaaacagc tatacctcca
     5041 gtcatccctg aaaatacagg aagaccaatc aagccaagta aaagataaac tccaacagat
     5101 atcaatccta gttttcttcc gagaaaagtt gctgttaatc caatagcaaa tgtttgccct
     5161 gtcaaaggaa ccaaaccaaa aggaatggtc atctgagaaa ggacagaaat aatcgcggca
     5221 aattccgcag caagtatcaa ttctttcaat gttcggttca taacgccctc ttttcgttaa
     5281 cttaatattt ttatttggtt aacgaaattg taaaacaaag tgattacttt gtaaatagaa
     5341 aatataaaaa aagaccagct atccaataga tagcggtctt tttcaagaaa gcttttgaaa
     5401 ttataagctt tggttgtagt attcaacgac aagagcttcg tcgatttctg gatatagttc
     5461 gtcacgttct ggtaaacgag tcaatgaacc ttccaatttt tcagcgtcaa agcttacgaa
     5521 tgctgggcgt ccaacagttg cttctacagc ttcttttact gttacgatgt tttgtgattt
     5581 ttcacgaact gagatcactt gacccacttc tacgtggtat gaagggatat caacgcgttt
     5641 gccatcaact aaaatgtgac catggttaac taattgacgt gcttgacgac gagtcgttgc
     5701 aagtcctaaa cggtaaacaa cattgtctaa acgttgttct agtaagatca tgaagttaac
     5761 accatgttta ccttctttga ttttgctagc ttttacgaac aagttacgga attgacgttc
     5821 gttcattccg tacatgtgac gaagtttttg tttttcagtt aattgcatgc cgtattctga
     5881 ttgtttgcca cggctattag gtccatgttg acctggtgcg taagggcgac gtgctaattc
     5941 ttttcctgtg cctgacaatg agatgcctaa gcgacgagaa attttccatg atggtcctgt
     6001 ataacgagac attaaaattt cctccaatga atataagttt ttggagtaaa ataatccgtt
     6061 gaaaaattca taatcatata gtttgttctt caatcttcac ctttgcagcc gcggttacac
     6121 aatcgaaccc gagacggggc aacaaactag ggatgagtta ttatttttct gctgcattat
     6181 tttacacaaa ttacagtata tgatagatca tccacgaatg tcaagataat tagtacataa
     6241 aaacgcttta caaacctagg ctgtctttat aaaatgagag ggtatgtgca aatggaaaaa
     6301 agcgaaggaa gtttaaggag aaaatcaatg aatccggtat caccattatt tgagaaaatc
     6361 gatgcttcaa ttgaaaagaa ggcgaatctt tttgaaaaca gcttttcacg ttacgctgtt
     6421 cgagcggttc tcgcctgttt gtttttgact ttaggaacgg ctgtggcatt tgcgatcgcg
     6481 atgaaggggg aagatatcgc gcatggtcta ggaaagattt tatacgcatt tatgttcagc
     6541 tggggtctgg tcatgattct atacatgaac gccgaattag gaacatcgaa tatgctttat
     6601 atgaccgtgg gtgtttttcg gcagagactt gctttaagta aggcagccaa gattctattt
     6661 gcctgtattt ttttcaatat gattggcggt atattatgtg gatttctaat ttctatgact
     6721 acgccatttc aagatttaac gttggacaac tttatgttag aatcaatagc agtaaaacta
     6781 gcaaaacctt cagcaacgat tttggtggaa gggatgtttg cgaatatcgt tgtcaatacc
     6841 gctgtactga tcagcatgcg gatgaaagag gatgtcggaa aagtgatcac agtcgtattc
     6901 atcattttca tttttgcttt tttaggatat gaacacgtga tagcgaattt tcctgccttt
     6961 acgcttactt actttgcttc tcacggacag atggatggaa tgacagtcag caatgtgtta
     7021 cataatttgt tttttgcttt ggcaggaaat tatattggtg gcggtttagt aatgggactg
     7081 ggatatgctt ggctgaatca gtcaaaatca tcctatgtgg actaaaaagt cgttcattaa
     7141 aggggaagtg ccatggaagt tttagttttt ccaaaaaatg aggaaaaagc gttacaaatg
     7201 gaaaagtaca tgaaaaatct tttttccttt gctggagtac ctaagccgga acgcgctctt
     7261 ttacaacaac cgttactgga tgagagcaaa aatttatcta tttctgaagt tttagctttt
     7321 gttcattatt attatgaaca aatcgaaaga gagtatcagt atgtagcgat cgatttagtc
     7381 cagaaaaaca tcaaacggct tacatttgaa gacttagtcg tattgttgcc actagttcag
     7441 aaaaaagaat ggtgggacag catcgactct tggagaaaag tatacagcac atggtgtaaa
     7501 gcctacccag agcagcgtga agaagtcttt caattgtttg aaaaaaagga agatttttgg
     7561 ctacgtcgaa tagcaatcac gttgcaatta ggttataaac agcaaacaga cacaggacta
     7621 ttgatccgag caatagacga agatcgtcaa acaaaggaat tctttatcca aaaagcaatt
     7681 ggttgggcat tacgcgatta tagtaagacc gatgccgatt gggtaaaaag acagctgaca
     7741 acagatttga gtaagttagc tgttcgagag gcaagtaagt atttataaga aagcgagacg
     7801 acaagagatg agacgcaaat tatttgcttt tgatattgat ggaacgttgt tagattcaaa
     7861 caaacaagct ttagatagca caagagaagc attggaaaaa ttacgcaaag ccggtcatct
     7921 ggtcacgatt gctacagggc ggagccgatt tcatgcgcaa gagatcattc gcgatcttga
     7981 ttttacgaac tacattttat gtaatggagc ggccggtttt ttagaccatg aacaagtata
     8041 taagaattta ctagatcgcg accagttgga tgcgttcgtt caagaagcgc atcatgagca
     8101 gatcgataca gcttttgtca gcttagacaa tatcaagcgt tcttcttcca atgatgtaac
     8161 ggtgatggaa gaagcgatgc attctttcgg tgctgtcttg cctgaattag atcagttttt
     8221 tgcagaggaa caagaaatat accaagcgtt agcatttttc gatcaaacat atgatgggaa
     8281 gttctcttca tatgataaaa ttcgatttgt ccgctggcat gagaacagtg tagatgtcgt
     8341 acctaaaaat ggttctaaag cagcgacaat tctgcactta gcagaacaag taggcatccc
     8401 tcatgaagac atcatcagct ttggcgatgg acaaaacgac cgtgaaatgt tgcgcatgtc
     8461 aggaattggg atagctatgg ggaatgctgt gccagaagta caagcagaag ctaagatggt
     8521 cactgataca aacgatcagg atggaatttg gaaggcattg aaagagttaa gcgtgattta
     8581 aaagaggttg tgaaaaagct gttctgcatc aagtaataag cccagccaaa caaaaatagc
     8641 tcctcctatt tttcgttttt ctgggcttat taccgcagat gcaagctttc gaacaccgtt
     8701 taaggaagag gtcgtgacag aagtggtcag tttcaagaaa taagaaggga tttacgaaaa
     8761 ttgcttctca aatttttgta aaattacggc ttatttctga agaagtagat gaaacaacgt
     8821 ttattcggga aatgggactg tgacaagatg tttgtcatag tcccattttt ttattttatt
     8881 tttcaaaact aagaaatacc aggaaagagt tccttttgtt tgaccttttc tttcttattg
     8941 aaaacaacta taatatagag tgatgttaaa agagaagagg aatttagtgt gcgggtattg
     9001 tttattggtg atgtagtagg ttcaatggga cgagagatga ttactgaata tcttcctaga
     9061 ttgaagaaga agtaccgtcc gcaagtaacg attgtaaatg gtgagaatgc cgcttctgga
     9121 cgtggaatca cagaaaaaat ctataaaaaa tttttgcaag acggcgtaga tgtcgtgacg
     9181 atggggaatc atacgtggga caaccgcgga atctttgagt ttgtaaatga agctaaaaag
     9241 atggttcgtc cggcaaattt tccggaaggg acgcctggac aagggatggt ctttgtcaaa
     9301 gtgaaccaag tcgaactggc agtgatcaac atgcaggctc gttcttttat ggtggacttg
     9361 gatgatcctt ttcgtaaaat gaatgagctg gtagaagaag ccagaaaacg tacgccgatc
     9421 atttttgtag attttcatgg agaaacaaca agtgaaaaac aagcaatggg ctggttttta
     9481 gatgggaaag tttcagcagt ggtcggtaca catacacacg ttcagacaaa tgatgcgcga
     9541 attttgccaa gaggaacagc gtatctgaca gacgttggga tgacaggtcc ctatgatggt
     9601 attttgggta tgcgcagaga acctgtaatc gaaaagtttc tgactgcatt accaaaacgt
     9661 tttgaagttg tggaacaagg ccgatcgatt ttaagcggct gtatcttgga attggatgat
     9721 acgacaggtc atgcaaaaga aatccagctg attcagatca acgatgatcg accgttcatg
     9781 gagtagaaag agaggcagtt ttttgcagca ggagccggaa attcaaaaag aagtaaggaa
     9841 actgacaaaa cttttaagag agaatgaaac gatcattcgc tacaaagaac ttgaagaaaa
     9901 gatccagcaa aaccagtatt tagctgagtt gagagaaaaa atcaaacaag cgcaaaaaga
     9961 tgctgttcat tttgcccact atgacaaacc agcagcagaa aaagaagcaa tcaaacaagc
    10021 ggatcaattc atgcaagaat ttgatcagca tccgcttgtt gtagcttata gaaaacagct
    10081 gttggaagca gatgatctgc ttcatcattt aacaactatg atacaagaag aaatcaatgg
    10141 acaaatagag gaggaaaaac atgcctcaaa aaactaaaaa tactcctatg atggaacaat
    10201 atctaagcat caaggcccaa taccaagatg cttttttgtt ctatcgttta ggagactttt
    10261 atgaactatt ttacgaagat gcgatcaaag cgtcacagct tttggaatta acgttgacga
    10321 gcagaaatcg aaatgcagaa gaacctattc ctatgtgcgg tgtacctcac catgcagcac
    10381 aaggatatat cgatgccttg attgaaaaag gctataaagt agcgatttgc gagcaggtag
    10441 aagatccaaa gacgactaaa gggatggtca agcgcgaagt gatccagcta gtcactcctg
    10501 gtacagtcat ggacagcaaa ggattgtcgg caaaagacaa caatttttta acagctgtag
    10561 ttagtcaagg aaatgaattt ggctttgctt atgccgattt aagtacggga gaattgaaga
    10621 cggctcggtt gcatgatgaa gaagctgttt taaatgaagc ctctgcattg cagacaaaag
    10681 aactcgtatt aggcagtgag atcactgata cccttcgtga acagctaagc gggcgtttag
    10741 ggctagtctt ttctcaacaa aatgagatgg aagaaaacgc ggaatttagc tttttgacaa
    10801 gcgaactagt cgatccgctg gaaaaagaag caaccggcaa actattgact tatttatcgg
    10861 tgacacaaaa gcggagttta gctcatatcc aaaaagcagt agaataccaa ccagatcatt
    10921 ttttgaaaat ggattattat tcaaaattca acctagaatt aagccaatct attcggactg
    10981 ggaaaaagca cggcactctt ctatggttgt tagatgaaac aaaaacagca atgggtggcc
    11041 gtttactaaa acaatggcta gaccgtccgc ttatccaggc aaaacaaatt aaagcaagac
    11101 aagaaatggt cgcttctttg ctagacagct attttgaacg tatcgatttg cagtcagcat
    11161 taacgaaagt ctatgatctg gaacgcctag caggtcgagt agctttcggt aatgtcaatg
    11221 ggcgagactt gatccagctg aaaacttctt tagaacaagt gccaatgatc agagggttga
    11281 ttgaaggaat cgatcaaggt caatggcaaa gtctgctttc agaaatgcag ccgatggacc
    11341 atctcgtcca attgatcgac caagctatcc aagatgatcc gccgttacaa ataacggaag
    11401 gaaacatcat caaagatgga ttcaatgagc agctcgatat gtaccgttct gctatgagaa
    11461 acggaaagaa atggttggca gaacttgaag caaaagagcg tcaagaaaca ggaatcaaga
    11521 acttaaaaat cggatttaac cgcgttttcg gttattatat agaaattaca aaagcaaatc
    11581 ttggaaatgc agaactggag aagtatgaac gaaaacaaac tttagcaaat gcagagcgtt
    11641 tcatcacacc agaactaaaa gaattggaga cacaaatcct cgaagcagaa gaaaaatctg
    11701 ttgatttaga atatcagttg tttttagctg tgagagaaga agtcaaaaag gctatccagc
    11761 cgctacaagt acttgcaaaa gcaatcagtg cagtagatgt gctacaaagt tttgcaacga
    11821 tcagcgaacg ctatcagtat gttcggccag aacttgtcag tgacaagcat cagcttctga
    11881 tcaaagacgg acgacatcct gtagtagaaa aagtattagg acatcaggaa tatatcccta
    11941 acagcgtaga aatggcagaa gacgaaatga tcttgctgat tacaggaccg aatatgtctg
    12001 gtaaaagtac gtatatgcga cagttggcat taactgttct gatggcgcaa atgggctgtt
    12061 tcgttccggc aaaacaagca gttttaccta tttttgatcg gatttttacc cgaattggtg
    12121 caagtgacga cttaattgct ggacaaagta cttttatggt agagatgatg gaagccaatc
    12181 aagccctgcg ttatgctacg ccaaacagtt tgattttgtt tgacgaacta gggcgaggaa
    12241 cagcaaccta tgacggaatg gcgttggccc aagcaatcat cgaatatatc catcgtcatg
    12301 tacaagcaaa aacactcttt tctactcatt atcatgaact gacggtactt gagaaagaac
    12361 ttccgcagct taaaaatgtc catgttggag ccgttgaaaa agacggagaa gttgtcttct
    12421 tgcataaaat gatggatgga cctgcggata aaagctacgg catacatgtg gcaaagatcg
    12481 caggattgcc ttccaatcta ctagaacgag cagcagatat cctgcatacg ctagaaaatg
    12541 gcgataacgg acaccatact gttccagctg aagtagaaga gaaaactaaa acagccaaac
    12601 aggagcaaat aaaaccacct gcagaaaaag taaatcaaga ccatatacaa gaccgtgtaa
    12661 aagaagaaaa ccaacagctt tctttattca gtgaattatc cgaaaatgaa acagaagtca
    12721 ttgaatcact gaagcaaata aatttactag aaatgacgcc aatggatgca ctaaacacat
    12781 tatatgaatt acaaaaacaa ctgtaggaag aaggcggata tcgatggcca aaatccaaga
    12841 attatctgaa cgtttagcta atcagatcgc tgcgggagaa gtagtggagc gaccagcttc
    12901 cgttgtgaaa gaattagtgg aaaatgcaat tgacgccggc agtactcaga ttgatatctt
    12961 agttgaagaa gcgggactgc ggacgatcca agtgattgat aacggagaag gcattttggc
    13021 agacgacgta gagaatgcct tcaagcggca tgcgacaagt aagatccata atcgcgacga
    13081 tctttttcgc atacgaacgc tgggctttcg aggggaagct ttgccaagta ttgcctctgt
    13141 ttctgaaatg actctggaaa cggcgaatca ggaagaaaaa caaggcacct atctgtcgct
    13201 gaaaggcgga gaagttattg agcatcgacc agcaccactg cgtcaaggaa cgaagattac
    13261 cgtcagcaat ctgtttttca atacgccagc ccgcttgaaa tacgtgaaaa cactgcacac
    13321 agaattagcg aacatcgggg acatcgtcaa tcgactggca ttgagtcatc catcgattgc
    13381 ttttcgttta gtacatgatg gaaacaaaat gctggcaact gctggaaatg gcgatctgaa
    13441 acaaacaatt gcgggaatct acggattatc taccgcaaaa aaaatgctga aaatcgaagg
    13501 aaaagatcta gattttgagt tatttggcta tgtttcattg cctgaggtga ctcgtgccag
    13561 taggaattac ttatcgacga tcatcaatgg acgttttatc aagaactttt ccttgaataa
    13621 agcaatcgtt gcaggttatg ggtcaaaatt aatggtcggt cgtttcccta ttgctgtatt
    13681 ggaaatcaaa atggacccgc ttttagtaga tgtaaatgtt catccgacga agcaggaagt
    13741 ccggctgtcg aaggaaaaag aactaacaga gctaattagt aacgccattc aaaaagcatt
    13801 gtctcaagaa aatctgattc caagtgcagc ggataatcta cggtttaaga aaaaagtacc
    13861 tgatcagcct aaaacagaac aaatcgaaat cgatttgtcc tacgcttttg aagaagaaaa
    13921 acctaaaaag ccaagtagtt tgaattttga tcgacagaca ggtacctttt tcgtagaaga
    13981 actaaagaac acatttgttg acagaattgt tgataagtct gtggaaaatg ttgaaaacta
    14041 ttctggtttt tctgaagaaa acaccactta tccagaaaaa acagcgaaaa cggtggataa
    14101 gtttggtgaa aatgttgata actttgtaga aaaaacagtg gaaaaatctg aaaagaaaga
    14161 atttcccatt gtggataaca tggagaaaac aaatgaagaa caagcagata aatccgtaga
    14221 agaggatgaa aagatttacg aggaagaatt gacactccat cctgaatttg atttcactca
    14281 aggaaacgac aaaacattag aacaagccat caagaaatta gaaacggaaa aaccagtaca
    14341 acgttttcct cagttggaat attttggaca gatgcacgga acgtatcttt ttgcccaaag
    14401 tagcgatggg ttgtacatca ttgatcagca tgctgcccaa gagcgcatta agtatgaata
    14461 tttccgggaa aaaattgggg aagtatctga tgatctgcaa gaattgcttg ttccatttgt
    14521 gttagactat ccaaacagtg atgctttgaa attaaaagag caaaaacact tgctagaaga
    14581 tgcagggatt tatttagaag aatttggtca aaacagcttt attgtacggg cccatcctac
    14641 ttggtatccc aatggagaag aagaatcgat tattcgggag atgatcgata tgctgctgac
    14701 aactggaagt gtgagtgtaa aaaaattccg tgaagcaaca gcaatcatga tgagttgcaa
    14761 acgatcgatt aaagccaacc attatttgaa tgaagcacaa gcacgtgtgc tgctgaagga
    14821 tctggcacga tgcgaaaatc ctttcaattg tccccatggc cgtccagtat tgattcactt
    14881 taccaattcg gatatggaaa ggatgttcaa acgaatccaa gacccgcatt aagtcaaaga
    14941 gaagagggaa aacatgaaga ttgtattagc atcccaatca ccaagaagaa aagagttatt
    15001 ggctcatatc gtttcagaat tcgagattga acctgctgat atcgatgaaa cgccatttcc
    15061 agacgaacag cccgtcgatt atgttcgtag aatggctgaa gaaaaagcac gaactgtctg
    15121 ggaacaagat gaaaaagaag accatttagt gattgccagt gacacgactg ttgttctcaa
    15181 tcaagagatc atgggtaaac cagaagatct ggctgaggct gaattcatgc tgaaaaaact
    15241 aagcggggaa acacatactg tatatacagc tgttgtttta aaaacaaagg aacgagaaga
    15301 acggatacta gcagaagcac atgtcacttt ttatcctttg acagacgaag agatcaaacg
    15361 ctacttggag acgggggatt atgcggataa ggcaggggca tacggcatcc aaaatgctgc
    15421 gagtgtattc gtcaaagaaa tttctggaga ttattacagt atcgtaggat ttccgattgg
    15481 tgctgtcaat caggcactga aaacattcat ttaaacaaaa aagcggacta tctgattttc
    15541 gattgaaaat ccatgatagc ccgttttttt tattgaaaag attacttatc tactctgact
    15601 aagattttac ttcagcttta ccgactgctt cgcccgggcg aacaagtcct gattggtcaa
    15661 gagaaagtcc tgcaactttt tcattattgg tcaaagcaac aataatgtca gttttcttgc
    15721 cagcttgttc tatttctggc aaatccattt cagcaatcag ggtctctggt gtgacaaggt
    15781 atccttcttt cacgaataca ttgaaaggaa caccctttag ttcaacagta tctaatccca
    15841 tgtgaacaag tacttccagc ccctcattag aaagaatacc aatggcatgt tttgtttcaa
    15901 agacactcgt cactttaccg tttactggtg catagacttt gccgtttgac ggttcgacag
    15961 cataaccgtc acccatcatt ttttgtgaga aaactgggtc atttacttca gttatttcct
    16021 tgatggtccc tgcagcgact gcgaataatg tttcttttgt tgcaactgcc gtaccagttg
    16081 ctgaaacagg ttcgaaagac tgtggcgttg ctgttgcgcc atttgctgtt tgaagttgta
    16141 catcagcagc attttcagga acagcaggat caatcttatt caaaattccc tgacgtctaa
    16201 agatgatcgt caagccaaat ggaatgatga cagcaatgat cattgcgatg atgaaaggta
    16261 cccatgtttc tgcttggata gctagtattc ctggcaaacc gcctactccg atcgcgttag
    16321 ctcgaacacc catcaagtta gcaaacatgc cagctaatcc agagccgacc attgcagcga
    16381 cgaaaggata gacgtatttc aaattgattc cgaacatagc aggttcagtt acgcctaagt
    16441 aacaagaaat cattgctgga atcgagattt gttcttcttt tttattccca cgatgtaaga
    16501 agatgatggc taagactgca gagccttggg cgatatttga taaagcaatc atcggccata
    16561 aattcgttga tccgaaatct gcaatcagct gcatatcgat ggcattggtc atatggtgga
    16621 gaccagtaat cactaaagga gcatacagga atccgaatac ggcactaaac aaccagctga
    16681 tagaagacgt caatccagta tttacgatat ttgagatcca gcttccgact gtccagccga
    16741 taggacctaa aataacgtgt gcagctaaaa cagttggtaa caatgaaaac aatggaacaa
    16801 aaatcatcga gatcgactga gggatatatt tgcggaagaa gatttctaga tacgctaaca
    16861 taaaccctgc cagcatggct ggaataactt gcgcttgata accaatcatc tggacttgag
    16921 caaaaccaaa atcccaaaat ggaatatctg ctgcggctgt ggaagctaca ctataagcat
    16981 ttaataattg cggagaaact aacgtaattc ctaaaacgat tcctaatatt tgtgtagtac
    17041 ccatcttttt tgcaatactc caagtgatac ctactggaag aaaatggaaa attgcttcac
    17101 cgggtaacca caaaaaggca ttgacaccat tccaaaactt cgagtgttca acgattgttc
    17161 caccaagact ttcaaactgg ataccttcaa gtacatttct gaatccaagg atcaatccac
    17221 cgacaatgat tgcaggaatc agtggtgtaa agatttctgc taaaacggca atagcacgtt
    17281 gaacgggatg aaggttttgt tttgcagctg cttttccttg ttctttggaa accccttcaa
    17341 ctccagatac tgcaacgaag tcgttataaa aagtagaaac atcgtttcct atgatgactt
    17401 ggaactgtcc tgcattcgtg aacatccctt ttacgctagg tatatcttcg atcgcttttt
    17461 cgtccgcttt tcctggatca ttcaggacaa aacgcatacg agtcgcacaa tgactaactg
    17521 cagcaatatt ttcttttccg ccgatatcat gtaacagctt ctcggcatct gcttgatatt
    17581 ttgccatatc aataaacccc tttctcttaa cttgtctatg caagttgttt cttcatttac
    17641 tatacttttt ttcggagaga attgcaagcg ttttattaaa aagtacgaga gaaaatgata
    17701 tcgttttaaa aagcttaaaa taagcttttc ttaaaaatag gaacattgaa atacaaaaag
    17761 agctgtagta tagtgaagaa atgatggaag aacgagtgag ggaaaaaaca tgaataagtt
    17821 caatgaaatt tttttagatt tggaacagaa aattttagcg aaagaatatc ctccgcattc
    17881 gcttttaccc agtgagaacc aattgatcaa aatttatggt gtttcacgag aaacaattag
    17941 aaaagcgctg aatcttttga ctacggaagg ttatattcaa aaaaaacaag gaaaaggttc
    18001 gatcgtactg gatcggaatc gcttcgactt tcctatttct ggattgacta gctataaaga
    18061 gctacaggag acccaacgta ttccaagtga aacgatcatc catacgttag aagaaacaga
    18121 agtgacaaaa gcattgaacg agatcactgg ctgggagatc ggtgcgcctg tttggcattt
    18181 gatacgcgaa agaaaaatca atggcgaagt agttatatta gacaccgatt atctattaaa
    18241 ggaaatcgtt cctattttaa ctccagcaca agcacaagga tcgatctatg aatattttga
    18301 aaatgagctt tctttgacga ttgcttacgc gcaaaaggag atcacagtag aagaagtaac
    18361 ggaaatcatg aaaacagcga tggatcttca cgatgacact tatgcagtag tagtcagaag
    18421 cctcgttcat ctggaagata cccgctgttt cgagtattct gagtcggttc accgattaga
    18481 taaattccgt ttcgttgagt ttgcccgacg ccgaaaagtg taaatagttc aaaagaaagc
    18541 aaattgttgg catctgtcca ctttggcgct atgataggat cacaaagggg gcatttttaa
    18601 tggataaacc aataagacca gaaaaagaag aactgaaaga aaagttatca cccatggctt
    18661 atgcagtcac acaagaaaat gcaacagaac gaccatttag cgggaaatat gatgattttt
    18721 acgaaaaggg gatctatgta gatatcgtca gcggtgaacc gttattcagc tctgcagaaa
    18781 aatatgatgc aggttgtggc tggccatcat tcagcaaacc aataacgaaa agacaagtgc
    18841 gcgaaaaagc cgatttttct catggcatgc atcgaataga agttcgaagc aaagaagcag
    18901 attctcatct cggacatgtg tttaccgatg gaccagtaga tcaaggtggt ctacgttact
    18961 gcatcaattc tgcctcactg aaattcattc catatgaaaa gatggatgaa ttaggttatg
    19021 gggtattcaa atcacttgta gaataatgga aatacacaaa gagcggtaca atacggggat
    19081 ttactcgatc gtccgctctt tttttattca agcgattgct atttgaaaga aacgctccct
    19141 agactccttt tttcacaagg tgaaatgtgc tacaataaag ggaacgtatg tgtgcaaaag
    19201 aaagaggact agaatatgta tgaatatctg acaggtgtgg ttacctttat caacccctat
    19261 tacatagtag tagaaaccaa tggtatcggc taccagatcg cactaggaaa tccttaccgc
    19321 tacagtagca aactaaatca aaaaataaaa atttatgtcc atcaggtaat acgtgaagat
    19381 gcgcatcttc tgtatggatt tgattcgcta gaagaaaagc aactgttttt gcgattagta
    19441 agtgtttcag gaatcggtcc gaaaagtgcc cttgcaatca tggcaagcga agaccactcc
    19501 ggtttgattc aagcagtaga atccagtgat gtcacttatt tgacgaaatt tccaggagta
    19561 gggaaaaaga cagcacaaca aatgatcttg gatctaaaag gaaaattcgg tgagctgagt
    19621 atcgatacac cttttagtct atttgatgaa gcaaacacaa aagacgctac agctctatct
    19681 gaagcaatgg aagctctctc ggctcttggt tacagtgatc gagaaatcaa acgtgtagaa
    19741 aaacaattaa aagaagtaga taatcagaca acggatgagt atctacgcca agcactcaag
    19801 ctaatgatga aaaaataagg aggagaccaa atgacagatg aatacttgtt atcaccagaa
    19861 tctggcgaaa atgaactgag tttggaaaaa tctcttcgac cacagctgct ttctcaatat
    19921 atcggacaga gaaaagtcaa acaagaactt cagatttaca tcgaagctgc cagaaatcgg
    19981 gaagaacctt tagatcatgt tctgttgtac gggcctcctg gattaggaaa aacgacgatg
    20041 gccatggtca ttgctaatga gatgaccgta aatattcgta cgacgagtgg ccctgctatc
    20101 gaacgtccgg gtgacttagt agcaatcttg aatgaactgg aagcagggga tgtcctgttt
    20161 atcgatgaga tccatcgatt acctagagtg gtagaagaga tgctttattc agctatggaa
    20221 gatttctatg tagatatcat ggtaggacaa gggccaaccg cacatccggt tcatttccct
    20281 cttcctccct ttactttgat tggcgcgacg acacgggcag gtatgctttc tgcaccttta
    20341 cgagatcgat ttggcatcat ttctcatatg gaatattatg acgaacagga tctgcaggag
    20401 atcgttttac gttcttcgga tatttttcaa acagagatca ttgaagaagg ggcattggaa
    20461 attgctcgcc gatcacgagg aacgcctaga atcgctaatc gcttgctcaa acgggttcgt
    20521 gattttgcgc aagtccaagg agacgggaaa atcgatcgtc ctatagcgga tcaggcactt
    20581 actttgctac aggtcgatca ggctggattg gattatgttg accagaaatt gttgcgaaca
    20641 atgatcgagt tatatggcgg cggaccagta gggttaagta cgctttcagt aaacatagga
    20701 gaagagcgtg agacggtaga agatatgtat gaaccgtatc tgatccaaaa aggattttta
    20761 aagcgtacac ctagagggcg aattgctact gcttatgcct atgaacattt tggttacgac
    20821 tatcatatat gatttttgct tttagattgg aggaaaatga atgagtgata caacacgtac
    20881 gaaacaattg atcaaaaacg tattgattga tttgtgccaa acgcaatctt ttcgaaaaat
    20941 cagcgtccaa aaaatcgcaa acgaagcaaa aatcaatcga caaacatttt attatcattt
    21001 tacagataaa tacgatttgc ttcgttgggt ctattgtgag gatgcattgc attatttaga
    21061 tccacaatgt ctttcacttg ataattggga agagcaagca ttgaaaatgc tgaaagcaat
    21121 tgctgagaag aaagaatttt atgcaaatac tgtgctttct gacccagaaa ttttacaaaa
    21181 agagttttct caactgatcc aaaaatcatt tatcaagatt tttgaacaaa tggatgaaga
    21241 aagacaactt tctgcaagag acaaactatt ttatgctcgt tttttttctt acggttgcag
    21301 tggtgtatta gtcaattgga tcacgaatga atatgaagaa acaccgatgg aaatcgctat
    21361 gcagcttttc cgtttagcca aggatacgga attatattct tatcgtcttt atgcaaaaga
    21421 agagttggaa gaacagtaat agaaaaattt tttgttggaa aagcaataat cgctaaaagg
    21481 agatggggaa atgacaaaaa ttttatttgt ttgtttggga aatatttgcc gttcaccgat
    21541 ggcagaaggc ttgctgagaa aacgaatagc attagaagga agggaagcag aattttttgt
    21601 ggattctgct gctacaagca cgtatgaagt tggaaagaca ccgcaccctg gaacgaaaaa
    21661 aatattaaac caagaaaaag tagatatgac gaatatggtt gctcggcaaa tcacacccca
    21721 cgattttgaa acttttgatt ggatcattgg catggatcaa gaaaatgtag aagaactgaa
    21781 acgaagagca ccacgctcag cgcaggggaa aatccatttg tttttaagta gcattcctgg
    21841 aaaagaaaaa gaaaatgttc ccgacccata ctataccaat aactttgatg agacatatca
    21901 cttgatcaca gaaggcctga atcattggtg gaatatttgg attgatgaaa ataaaataac
    21961 aaacaatttg taaagttaac gctttctttt taaggcgatg ttagagcatt tccttgtttt
    22021 tttgtaaaat gttaggtaaa ataaaattaa ttaagtaaca ctttcttagc taaaggagga
    22081 gtgcattcga tgaacgaaga gacagtatcg ccaatgaaga agcttacgaa gttagttact
    22141 catacttcgt atcaactttt tgattctttt gtaaatgaca ctgaagaaca tgctaagaat
    22201 gtacgattgc aaggaaagtt tattcttgag ctgcaaaaag ctgctactga acatagtcta
    22261 gttatcttac aagtaagagc aaatcgtttg agtagcaagt atgaaacgat ctcaggctgg
    22321 gtggcgacaa aaacggtcga aaaagaccga gtgatgatcc gcctacaaaa cgaagagcag
    22381 cagatccgga tggttcctgt agaacaaatt gaaaaaataa caatcctttc accagcaggg
    22441 gaacaggaac ggttatcaaa ataatttata ccagatagaa aagcacgtat gagcttgtac
    22501 catcaatcat tactaatcaa aaataaccga atgctttaag ctgatatcag taaaacggaa
    22561 cgttttagga tgagtatcat agcatgacag cattcggttg attagttgaa tcgattggat
    22621 ggtacaagtt tttttgataa aaaaaggtcc tgctagccgg ggagctagca ggataaggag
    22681 ttaaaaatga aaaagtgttg ttagggttgt ttgttggtat gcttatataa tagtcattag
    22741 ttgtgaatat tttgtgacga aagttttcga aagttgttaa gtttttgaga gtataaaata
    22801 ttttgtgtaa atgaaaaaat ccatacaaaa aaggaagtcc cttctgtaga ataaagttaa
    22861 cgacaaccaa ttcacagaaa agaggacttc cctatgaatg attttactac agaaattgtg
    22921 caaactctag tcactaaagg cgatttaaat gaattattcc gttcgcactt agaaaaagcg
    22981 ataaacacac tcctacggac tgaattaacg gcttttttag attacgaaaa atatgatcgc
    23041 actggtttta attcaggtaa ttcgagaaac ggttcttact ttcgatcaat caaaaccgaa
    23101 tatggtgaat taacattgga aatacctaga gatcgtaatg gtgagtttaa acaacaaact
    23161 ttaccagcct acaaaagaac aaacgataca ttggaaacca ctattatcca tttattcgaa
    23221 aaaggtgtta cgatgtctga aattgctgat ttgatcgaaa aaatgtacgg tcatcactat
    23281 actccacaaa ccatgtccaa catgactaaa gttctgactg aagaagtaaa tgcctttaaa
    23341 tccagagcct taaatgataa gtatgtcgct atttttatgg acgctactta cattccacta
    23401 aaacgtcaaa ccgtatccaa agaagcgatt tatattgcca ttggtatacg agaagacggc
    23461 actaaagaag tactgagtta tgcgattgct ccaactgaat caacatacgt ttggaatgag
    23521 ctgctacagg atattaactc cagaggagtt caagaagtct tgctttttat tacggacggc
    23581 ttaaaaggca tgaaagatac tatccatcaa atttatccta aagcaaaata tcagcattgt
    23641 tgtatccatg tatctcgtaa cat
//
LOCUS       DAZAOD010000033        23651 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000033 DAZAOD010000000
VERSION     DAZAOD010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.034"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(169..621)
                     /locus_tag="ACHDPO_001351"
     CDS             complement(169..621)
                     /locus_tag="ACHDPO_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368990.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(628..1176)
                     /locus_tag="ACHDPO_001352"
     CDS             complement(628..1176)
                     /locus_tag="ACHDPO_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFN3368991.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(1221..1553)
                     /locus_tag="ACHDPO_001353"
     CDS             complement(1221..1553)
                     /locus_tag="ACHDPO_001353"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368992.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(1567..1824)
                     /locus_tag="ACHDPO_001354"
     CDS             complement(1567..1824)
                     /locus_tag="ACHDPO_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3368993.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(2019..2561)
                     /locus_tag="ACHDPO_001355"
     CDS             complement(2019..2561)
                     /locus_tag="ACHDPO_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFN3368994.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VGQEAQKIDAIKIYYVRSAY"
     gene            complement(2582..3673)
                     /locus_tag="ACHDPO_001356"
     CDS             complement(2582..3673)
                     /locus_tag="ACHDPO_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFN3368995.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(3681..5891)
                     /locus_tag="ACHDPO_001357"
     CDS             complement(3681..5891)
                     /locus_tag="ACHDPO_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFN3368996.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(5907..8435)
                     /locus_tag="ACHDPO_001358"
     CDS             complement(5907..8435)
                     /locus_tag="ACHDPO_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3368997.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(8487..8897)
                     /locus_tag="ACHDPO_001359"
     CDS             complement(8487..8897)
                     /locus_tag="ACHDPO_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFN3368998.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(8910..9128)
                     /locus_tag="ACHDPO_001360"
     CDS             complement(8910..9128)
                     /locus_tag="ACHDPO_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpD family membrane protein"
                     /protein_id="HFN3368999.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(9125..10117)
                     /locus_tag="ACHDPO_001361"
     CDS             complement(9125..10117)
                     /locus_tag="ACHDPO_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFN3369000.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(10196..11107)
                     /locus_tag="ACHDPO_001362"
     CDS             complement(10196..11107)
                     /locus_tag="ACHDPO_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFN3369001.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVSAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(11126..11470)
                     /locus_tag="ACHDPO_001363"
     CDS             complement(11126..11470)
                     /locus_tag="ACHDPO_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369002.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(11490..11768)
                     /locus_tag="ACHDPO_001364"
     CDS             complement(11490..11768)
                     /locus_tag="ACHDPO_001364"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369003.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVLQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            complement(12127..12627)
                     /locus_tag="ACHDPO_001365"
     CDS             complement(12127..12627)
                     /locus_tag="ACHDPO_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369004.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(12628..13173)
                     /locus_tag="ACHDPO_001366"
     CDS             complement(12628..13173)
                     /locus_tag="ACHDPO_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369005.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(13170..14426)
                     /locus_tag="ACHDPO_001367"
     CDS             complement(13170..14426)
                     /locus_tag="ACHDPO_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFN3369006.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(14786..15097)
                     /locus_tag="ACHDPO_001368"
     CDS             complement(14786..15097)
                     /locus_tag="ACHDPO_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369007.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(15120..16595)
                     /locus_tag="ACHDPO_001369"
     CDS             complement(15120..16595)
                     /locus_tag="ACHDPO_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFN3369008.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(17044..17496)
                     /locus_tag="ACHDPO_001370"
     CDS             complement(17044..17496)
                     /locus_tag="ACHDPO_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369009.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(17498..17863)
                     /locus_tag="ACHDPO_001371"
     CDS             complement(17498..17863)
                     /locus_tag="ACHDPO_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369010.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(17962..22245)
                     /locus_tag="ACHDPO_001372"
     CDS             complement(17962..22245)
                     /locus_tag="ACHDPO_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HFN3369011.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(22392..22631)
                     /locus_tag="ACHDPO_001373"
     CDS             complement(22392..22631)
                     /locus_tag="ACHDPO_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369012.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(22721..22963)
                     /locus_tag="ACHDPO_001374"
                     /pseudo
     CDS             complement(22721..22963)
                     /locus_tag="ACHDPO_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(23076..23312)
                     /locus_tag="ACHDPO_001375"
     CDS             complement(23076..23312)
                     /locus_tag="ACHDPO_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369013.1"
                     /translation="MFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTELKDKN
                     NVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
BASE COUNT         7009 a         5098 c         3442 g         8102 t
ORIGIN      
        1 attttgaact ttaactttta aaaactttaa aaataatctt atttgttctt ctaaacaatc
       61 atctatactc atataatcac tccactaatt aatctcccca aaaagacaca gcattaagag
      121 atataccaac acaacagtgc aaataactct acatcttcct tcgcaacctt atttcaataa
      181 accataaaaa ttatttttta atagaaactg aaaattaaaa ctagaaaaag tagttttacc
      241 gaatgtaaga gcatcatcac catcaatata gaaatacatt cttttccagt tacatttaat
      301 ttttaaacaa aattctcccc aaaaaggaac tttttctagt gaaaacttgg taatctcttt
      361 gtaattaatt cttgttaaag aataattaaa cacttcattt ttacttgtta ttttttcatt
      421 gactataact agttcatctg gtaaaaaaat taaccaacaa acatcgacaa acagtaaatg
      481 atataatcca tttccacctc caagcatatt caatactggt gaacatgcct tagaaacacg
      541 aatatagtta tggtttaaat agatattttc tttaaacatt gcttgtttaa aagccatatg
      601 ctcttgttct aaacttttca taaactttta ctctaatgca cagctagcag cagctgctgc
      661 aattcctgct acaatattta ccttagctaa ctctttagct gcagcttttc ctaattgttt
      721 ttctgcaatt tttaataata aatccgcagc tttttcaaaa ttaaaagctt ttaatgcttc
      781 aataaaatct ccctgcgtac ctatagccca agccactcct cctccaggaa gagaattaat
      841 ggctacacat ccagcatatc gtttccaatc aactttctcc attctaggaa caataatatg
      901 ttcataaaag actcttgctg ctcttccttg ttcgttatct tgactgattc gttcacgaat
      961 agcaccaaaa tcctttatat ggtatacacc atgttcgtct aaaaaaccaa ctgtatcaaa
     1021 ataaaaagtt aattcatcta ctaatttatt ctttatttct aaatcaactg tattcacttt
     1081 ttctgtggca tacacacttg ttccagtact aacaaaagta cttaaaccta ataagaaaac
     1141 acctaaaaca ccaaatattt taattattct tttcataatt tctcctccat aaaaaataag
     1201 ttacttttta aatatcttgt ttatgaattc attccccaaa ggccttttaa gattgataca
     1261 gcagtccgtt cacttctttt agacttgtca tacaagtctt ttaaatgatc ccatatcaga
     1321 ctagtttgtc tatctagctt caatccatta aacgctaatg aacggttcat tttttctatt
     1381 actttagata aagctacaga aatttttata ccttcacaac gcgcatcttg gatttcaata
     1441 atagtatcat caattagttt ttgaatttct tgcctatcaa catattcaat cttagaaaga
     1501 gaatctttta aagctactaa tgattcaacg atttcttttt tctcttcaga cattttcttc
     1561 ctccttctag tgacccgtaa agccatgtag agcagagtcc attgaaccag taattacact
     1621 atctacaacg ccattccaat ttactctaca ttttccattt ttcagatttg tcggtccata
     1681 cggatagcct ttttgacatt caatgttcgg attataccag ataggattat accattcagc
     1741 cgcagaagca gattcagtcg atacaaacaa tcccacacca acaaatccaa tacacatcac
     1801 actatagcca attagttttt tcatctcgta tccatctcct aaaaaataga atagttctta
     1861 tagttattca taagacatat tttttccgtt tttgttttat cctttctgtc ctataacaac
     1921 ttttttcaag taaagaatga catagttttt cttaaaaaaa cagtctgttt ttttctattt
     1981 cttcggtgta taataaatat gagtgttcat tttttatttt aatacgcact ccgtacataa
     2041 taaatcttga tcgcatcaat cttttgagct tcttgaccta ctttcaattg aagtaataca
     2101 aattgagtaa ccttattcat tgtttcttct ccaaataaca aatattgatc cggattctct
     2161 atatcttgtg tcacctggta aagtttccca gttgttttca tttgtacatg cgggtctaca
     2221 tcaatactat tgtctttaat acaacgatct gtcatatagt ccctcacagc ttgattgcgt
     2281 ttataaacat ctgtgaaatt actccatttt ctagcaaaat cttttaagaa attttttgtc
     2341 atttcatcta tttgcatttg ttgcgctgtc tcgtcttcta atgaaccaat ttgactgtta
     2401 ctttcagtac tttgaagagt tccacttgtt tcttttactg cttcgattgt ttcttctgtc
     2461 gttctcaatt gtgttttttg tttttcagaa gaaaaccaat gacaaccagt aagacctatc
     2521 aaacataacc aactaaatac taaaattatc ccttttttca cgtttctagt cactgccttt
     2581 cttatttcac cttacgaacc agactacgaa tttttgtttg attgtacgtg cgttgatacc
     2641 gagccataat ccgtccttgc tcggcattct gttccacact agagaaatgt tgtccgccat
     2701 atgaaacatc tgttataatt ccggtgtgac catagattcc aggagacaat gcaccacctg
     2761 cttgccaatt caccacatct cctgcttgta aatcacttgg ttttgggttc atgattactt
     2821 gccaaccata ggttgtccag ttataatctt cccctattaa catcgcaaac atgtgtccag
     2881 aacccattaa ctgtgggcca cctaattgag atacatacca tgccgtacca ccataacatt
     2941 ccccattatt tacggatcgt ccaatgatcc gatccaaaac cttcgcattg cctttacttt
     3001 ttcctgcaat aagcgaagtt ttttttgttg gtaggctatt ccaatgcttg atcgcaaaag
     3061 tatcatattc cgttaagtta taggacgtta tgatactcat tgctcctcga taatacggac
     3121 tcccttcggt aatacctgct gccgcatagc ctccacgacc tagaatcaat aaacaacttc
     3181 caggatcttt attgcccaca cattgattaa agttgctttg gctcgccacc ataaagccat
     3241 aatagtcata acaagctttt aagttcggaa acttcatata gaaaccacct tcagaaccac
     3301 caattccacg tgcagaacct tgtgggtagg gacaaccagg aaaccaggta atcccaaaaa
     3361 agttcgtatc gtttcttcca gattgtgact gtccataagc tgattcatag cctaattgag
     3421 aaagaatcac actcggtaat aactgatact ttacagctgc accaactgct gcttgcgcat
     3481 gttcatctgt gattggacca cgtcctttaa tctctgaaaa aatcggtaat ccttcggtat
     3541 attccccatt aaaagcgaca gctagacctg tagcttctcc tccatgctca gaaagttctc
     3601 ctgaaaaaaa gaatggcaat agaaaaaagg gaagaataaa gaaaagaaga caacctagac
     3661 accctttctt catttcttcc tcatcctttc ttcgataatg gtttttggac tgttcgtcct
     3721 tttggtaaag taaaatcagt tcctggtttt gcgtccaaaa tcggcagtgt tttaggatcc
     3781 ttttctattt tttccgattg ctctgttggc ttatctaaag aagaaaatgc aggttgtaac
     3841 gattttggtg cggaaatcga cggtttactt tcagacgaac gttgccccgg ttgttgcaca
     3901 gaacgatttc ctgatagagt ggctaccgac gaattaggaa cagagtattg gttcaataac
     3961 tgctgcattg ctggataact cccatttttc gcctgatttt tcacttggcg aatctgttgt
     4021 gaaagagaac cagcagctgt taattgtggc acgggtactt ttccagaagg caacggaatc
     4081 gattgaccaa caaaagcgat acctttattt aacaatggtt ttctttgatt attcccttgt
     4141 tgcttactca attgtgccaa tgattgtacc tgttgttttg gtcttactga attcatggac
     4201 gaatttggaa tcaaaccatt tgaaagacca gaattccact ctgttttcga tttggtagaa
     4261 gacatttcag gctctacccc atgataacga acatgacgac cactataagg caaggcttga
     4321 tttgaacgcc cacctagttc aaagggatta accacttgcc tcccttttac cgattcttgt
     4381 ggtgtacgtt tttgttgaaa cttttgaaat ccatgtatcg ctgcagaagc gagtggattc
     4441 gttgctcgat acacattccc tgctaatcct gcacctttga ttgccaaatt ttgtccagca
     4501 gttgatagtt gaccaggcag ttgtttcatt tgagacaaag aatgacttgc tatgtttttc
     4561 gtgttgttta tagtttgatc tgcagctcct aaccctagtt tctttaataa atctttccgt
     4621 tttacaatga gtaaaattga taggagtgct ttgacaaaca tatttcctaa aaaaccaaaa
     4681 acagtattca ttggaattaa atcgtctact atgttataga tcaaaaatgc caccaaaata
     4741 atcacactgt aaaaagattt ttgaaacatc aagcccaaaa aggactttaa ggtattcatg
     4801 agcatataat caaatactgg aacaaaagaa gcgagtaatg aaaaaggaat cacaagtaat
     4861 aaacacaaca ccaacatttg aaagataaaa cgaatcatgc caatcactac aagtggtaat
     4921 ccaatactta gattaagcaa tggcaccata gaaccaacga ctgctttata aacagcttta
     4981 gttggttgaa tatagacacg ataagccttc tttttccctc tatcttctcc tgcagcagtg
     5041 gtcacttttg tctcaatatc agataattct tcacttgacg cttccttggc tagaaattct
     5101 tgtggttcaa tctctgcttg atacaattct tctaaatttg ttgtcccata atttaacaat
     5161 atatacggat caacaacagc cgctttataa taaagttggc gcactttttg aatggcttcc
     5221 ttttgtgtcg ttggcactaa aacaccattg acatcttttg tcgccaattc atctagacta
     5281 tttgtagcag aaaaaataaa gccttctacc tccacggaca aatcatttaa ccctttggta
     5341 aaagcttctc ctttactagg tacgttacta ccatagccaa accaaaccat tgaaaaaatg
     5401 acaacgaaga gaaatcgaat aaacaccatt tttgcgtaat gtttccctct aaatatacga
     5461 agagtaaata gatataacac atacaagacg acaatccccg caccaatagg atcgtatatt
     5521 tttgaataaa tagtatccga aaaagtgaaa aactggtgaa ttaactcgtt cattgcagct
     5581 ccttcataga gcttctcaat gacaaaatca aggccttgcc aaatcaattt acttaaacta
     5641 aagaacatat tcgtcatcat ttttagaaaa tctgtgccat ttgccccaaa taacattttg
     5701 cctaatgaaa attcactatc agataaataa gaagaaaagg tatcaatatg aaatttccca
     5761 atctcataga tcgattgatc cacctgcttt tctgccgcat acaccaatcc accaacaaaa
     5821 agcagtccga atccaatcgt taaaaaaaac aaaacgcacc atttcttttc cttatgcttt
     5881 atataagcca ttgtttcacc tcatttctat tgcatgatta acgtatcctg ttcttctact
     5941 tgagagtgac ttgttttttc cgttgtttgt aatgcagcgg tcatttcttc aaacaaactg
     6001 tgtacattga gttttcctac acgtccatag ggatctaaca tccaacactg tcctttaatc
     6061 atgtggctca tttcagctaa gttcgcttca tttacttcca aacgtaaatg attcaaaatc
     6121 ttttctcgct cactgtcttc atcaaaagca aagacgacac caaaattccc tttttcttta
     6181 tctgaaccta agtcaccaat aaattgtgta tctaacacta attgattcat ctgggaacgc
     6241 cccacacgtg ccattgctgc aataatacta cgtcctgcgt tcgaattatt aaatacccat
     6301 gcttctgtaa aataaatcgc tgttttctta ctactatctc gttttccaaa catttcacaa
     6361 aaacgaccta aactaatcat caaacacaaa gactttcgat ccgcatctgt atatagttct
     6421 ggtcggacat tgtcatttgg taatttcaaa tcttggatct ctaaaatcgt tgttttggca
     6481 ttaaagtcta atcccgggtt ttctccataa gaaaatccta aacgtaaaat cgaatcttct
     6541 accgtcaagc gtaaaaactc accatattct cgaacctctt tttgttccat ttgttctaaa
     6601 tagtcgacca catgcatcaa gccaacttgt tgtccggctt ctttttgaac taaaacttct
     6661 tggattccct ttaataccgc cccttttaaa aggtgattgg tacctaacgg acttaactca
     6721 tcaatcatat cctgggctac ttgtttcgca tctactcggg ataaacaaac aattggatct
     6781 aatacaccat aattacgggg atttgtagca tctaacgtga cataactcat tttttgcaaa
     6841 tgttctacaa acaaagggta atgtttctga taatacgggt cttgaatgag tttcgtaaac
     6901 catttgcgct tttctccttt gggatccaca aataaacttt gtacattcat aaacgaacta
     6961 tacaaaaaga gcaagccaac taaaaaggtc ttccctttac cggtttttcc agttactgct
     7021 acatgaggcg catcaaacaa cgcacctttg attccttccg caatggctag aagattcaaa
     7081 aagacaaaac gatttgacgc ataaattaat tcttctaatg gtgttttttc tcctcgagaa
     7141 ccaccatccc ctaatgtatc ttgccgacca atataccagc cggattccat acctaattct
     7201 gatactgctg aaaacaacca ttcgccaact gcttctacag ttgttcggtg cttccaatgt
     7261 aactgccgtc ccaatggttg ccctaataaa catttataga acaattctcg ttgatcattt
     7321 tttgcacggt ggatatggat aatcgtatga agttgttgaa taaccgttgc actattttga
     7381 cgaacttctt caaccgtttg accgtataca ataaaacatg cgatccaatc gacgacaggt
     7441 tgcccattat ctactcgttg ctttaaatgt tttactaatc ctcgaacagt taataagcgt
     7501 tcactaggtt cttcatcatt ttgaaccaat tccttatgct ctgttttgaa ccgttccgat
     7561 agccaattca gttttaaacc aatacctccc tgtcctttca agcgtggata gtgaattttc
     7621 attcgcaatt ctgctgggaa agaaagatcc tgagcaaatt gaaatagatc acaatttctc
     7681 atattttcag gtgtttcccc aataggcaac aatgctaaat aactactccc taactcatct
     7741 tctaattgaa gaaggccttt atgttccttc ggtatacgta catacgttcc ttgattgtct
     7801 ttcagtactt cccaattatt ttgttcttct actttgtgag ccattcctcg aatatattgc
     7861 agacgattga gatacaacag ctcttttttt actaagggac gaatagaaaa gctataaagt
     7921 aattgtgtca cttcttttac ataaggatca ctttcagaaa acaaagtttc caaatcatct
     7981 acttctaatc caaataagcg tgctaaactt cctgctaaat ctaaccagat tagatttatt
     8041 acatcatgaa aactctccac cgttgctttt tctttgactt tgattcctaa aataaatgaa
     8101 ggacgataga cttgaccttc tcgttccaac aatgtcactg tttcttttgc ataatacgca
     8161 ccaattgctt gactatcggg agaaaatccc tttcctaatg tgtcaaactt cgtccgtaaa
     8221 ttcattgttc gtggatacat caccaactcc acatcttcat aatctgctaa aagcaacagt
     8281 aaacgagcca tcatttcttt tatttcctgt gtcttttttg gtgtgttttt tgaaattgtt
     8341 cgtggaaaaa catgatagta ggcccagata caatcctctc catttaacaa acaatttttc
     8401 ttgaatgctt ttactggttc ttttacaagc accaatgaat ttcacctccc aataaaaaag
     8461 gaacaaccag ttgattgtcc ctttttctaa tcctctaaat aaacatactt attcacaaaa
     8521 agtaattctt ccaatgcatt gtttgatacc ttgtcccagt tataatacac acaatcacca
     8581 ttcatcatac gaatcatata acaaaaccaa tcccataaat aaaaatgcac tttttttcca
     8641 tcaggtttta gttttgccag tgctaacaca cataaatagg ggagtcctat ataaaaaaca
     8701 actcctgctg gtggaaaaaa agaaatgacc caaccaataa atgaacgtaa aaataaatat
     8761 tcaaagatta cgaccaacaa aaaagttgct gcattgacta atgcaactgg aaatggaaga
     8821 cgccaattgc ttgtaatctg ttgtacgcga taaggttccg cataaacaat cgaataatca
     8881 taaggttccc aatccacttc actatcctcc taatccataa ataatttttc aatgatttta
     8941 ccaaacgcat caaatacacg tgttggatca tttaagaaga aataaactgc ggcacctgct
     9001 gcgatagata ttaatgcatt tcctactttt gatttcataa aatttcgcaa tcccagataa
     9061 acaaccacca ttattaaaaa atagccacct tgcgttaata taaaatctac aattcccttc
     9121 agtgtcattt ccgttcttct cctttcctat ccaaccaatt atgtgttaat ttttcaacat
     9181 aatactgatt tgtttttttc gtaatgacaa tcgtcatttg ttctttttgt aaaagtgacg
     9241 tatcaccatc tcgaaagacg accgttgctt ttacaataaa aggttttttc gtttctttat
     9301 aacgcaatac tttcatctct acttgatcaa ctttagctgt ttgattgagt ccttcaggtt
     9361 ctttcatcat gtatgacata tcttttgcat tgtttttcgc atacttatct aagaaatctt
     9421 ccacaaatcc ttcaacatct ttcgcttccg acgcatcaac cgtttcgtat aatgtgtcat
     9481 cataagtaat cattcgttgt ttttctgtat tctttggtag tgccgtaaaa taaggataag
     9541 caataatacg acagcccttg tttgaaatag aaaagggaag attgagtact tgtgtgattg
     9601 tcacacttgt ttctttctta ctctctggat tcatcgagcg aatatcataa gttactttat
     9661 aactagcagt tggaatggtt tcaatttctt ttaatccaat aaacgaagca gcagttaatt
     9721 ttcgaacacc tgaaacactt cctggttctt gaataaagtt ttgtgcataa aactcttttt
     9781 ttaatgtttc ttgacgttgt tgttcttgtt catgattatc gaatgtattc atatacaaag
     9841 caacaaaacg attcataaag gattcaattt caggtgtgta cgttaattct gaccgacttt
     9901 gtacttcttt cttttgtaat tgttggattt catctttcaa aaacgacact tgaaccttcg
     9961 ttttcatgga ttgaaaaaat gccaagcccc ctgaaaaaca aagaaataaa accaaacacc
    10021 aaatccattt cactgctttt tttgaatgga ttttcttttg cttcggtact ttctctgtat
    10081 aaactttttc tttccgccgt agttgtcgtt ttttcataag ctactccttc tagtatgttt
    10141 ttactagtac gtacgattga caacgataag cttgtttttc tgaaaaatag tccattcaat
    10201 taccctcatt ttctattcct tttctctttc ttttatatcc aacaaatcca gcaatacttg
    10261 tcaacactcc tcctagaaca gaaagtgcaa catgtatttc ttcaccagtc tttggtaaga
    10321 cttttgtttt tccatctgct gttttgattt caatattgcc acttggaagt ttctttacag
    10381 gaatcgacaa atcctttacc aaattccctt cactatcttg gattaatgga ataccatctt
    10441 ttacaccaac aattgtttga tcacctgcta cttttaatgg ggtggttggt gttggaatat
    10501 gggtcaattc ctctacatta ctagtgacaa tcggtacact cattccttga gaagtattcg
    10561 tcgtaatttc accgcttggg gttaccgata ctgtgacttc ttttgctgaa acaataggtt
    10621 tattttcttt tggaattgct tctgattttt caacaggttg tttcggttct tctttttgtt
    10681 cttcactggt agacgacatc gttggctgtt ccgtacttga cgaatcagta ttcttttcag
    10741 aagaactggt tgttcctgat tgttccggag ttgtgactat acttgaatcc gttgttgttg
    10801 aactatgcac accttcttct tcgatcgaat cagtcggtaa agttgattca ggaaactctg
    10861 gttctggtgt cactggctct ttttcaggtt tctctgactg caattgttca ggttctgctg
    10921 gtttttccgt tgttcctcca tttagctctg tctcaacatc tggtaatcct tcccctggca
    10981 atgtttctac aatttctgac ttaggtgttt ctacagtttc atctgcataa accaatgaac
    11041 tccctaattg aaacgaaaat aatgaaattc ctagtgttgt tacgactgct aatgttgttt
    11101 ttttcatgat tattcctcca attttttatg caattcgtgt tttgttcata gacgccgcac
    11161 taatattatc tgaacgataa aagaactccc gtccgttttc ttctaaccca acatatggat
    11221 tatttttgaa taattgaatc aatagttcac tggtgttgta ttttggatag tttgcaaaaa
    11281 aataatactg tgcttgtcgc ccatccgaaa attcaacaag taattcataa cgataccgct
    11341 tcaatccttt tcgttgtttt aaaggatctc tataccaact tgtccatcgt tccattcgtg
    11401 gatagagata gacacgatac acatagaaca atgccatacc acataccacc aaaaataata
    11461 atcgccacat aaaaattccc ccttttcttc tacctttctt gaatcatcga acattcatac
    11521 cctctataga gatttgaaaa atccatcatc aattgttcat ataaacgttg ttgcaaatag
    11581 cgattgtttc gaatacataa ttcttcatag ccatcaatca cttgatcttc tttttcatag
    11641 catcttgtag ctctatgacg ctcagcttgc aagacataac caaactctgc accatatcgt
    11701 tctactgtta ataactgttg actacgcaat aatgcaatat aacaatcaca aaaatgttca
    11761 accgacattt gatttttctc acgtttgtga aataggtatt ctttagaaag cacattattc
    11821 gttaaacaat ctgataaata gcgataatct ggcggtcggt tattttcatc tgtgaatttt
    11881 tcccataata aactgatttt tattcgttca gcggctagat agtcttgttc gcgtggataa
    11941 aattcatcaa tcgcacaaag ttttttatca cctgaataaa caaatccata taatgcgaaa
    12001 cgaactcttc cttttcaatt ggctctccta aaaattccag tgacatacca tcttctcctt
    12061 cctaaaaaaa ataaaaaagc agaaaccgat ttggcttcta cttttctttc cttttatagc
    12121 tcttttttac ggaagaatcc gcaaatgaca ttttttcaaa aaatcaatcg gcacaagttc
    12181 acgaaaactt ggagcaattt tggatagaat cacttcccca tcttgtaaaa tacaatcata
    12241 aaaatcatca gttacttgat acttacgctt cttacaataa ttgataaaat agtagcgatc
    12301 attttctatt tccattcgtt gttctactaa gcgcatacga acatcatcat agaaataagc
    12361 cacaaatcgc ccttcaagtt catgtttttc aatgggatac tcttctggta acaatctatt
    12421 ttttcgtcgt ttatacattg ctggatacct tagaagaagt tcatctaaac gtctgtcagt
    12481 atatggtaac tgacgaatca acgattctaa tcgttcttta tacagataga ataattggcg
    12541 caagcaatag tgtaccgcct ctggattttc taatactgtt ggatcacgtg accaatacgc
    12601 accaacataa atcataattt ttttcattta gacaatcaca ccagcaatac taatgaccga
    12661 tccacaatag gtagaacaag tggcatagcg accaatttcc tctaattcta tctcaatctc
    12721 ttctaaagaa agatatgtct gttcttctgt tggctggcga ctcatttccc aagtgacagt
    12781 caccaatgaa atttcttcca taagaggttt ttcgctgcta agtgctgcca cacagttttc
    12841 atatatcttc attttatcgc agcctttttt aaccgctaaa atcgcaggta ttggcaatga
    12901 aaatcgataa aagcgaatga attctagcct tcctttcctt cggctaaatt ccaactcttc
    12961 gagttcttgt tcgtatccct tacgaacttc taataagcgt gcaatttctt gccagttctc
    13021 tttttcctga taacgtccag cttttaccgc ttgttcaata taaggaactc gaaaacgaaa
    13081 ataagacaaa tcaaccatct tttcatttaa tgcttcgatt gcagccttta aatccaacag
    13141 gcgcagccat tctgttgtcg tatatgcatt catgcaattt tccctcctga cgttcccatc
    13201 cattctagat agttttgttg ctcgtcattt agttcggcat tatcaatccc ttcttgtaca
    13261 aagtctcttc ctaaaatacg atctgcttct tgtaacaact ttaatgtcgg agctacttgt
    13321 ttcaaaaacc agcgttctga acgatctaat gagaattttt ctggctttac tgtaaaatcc
    13381 aattcttcca tcgaacgaaa taattttgcc catcgtttat caacaatccg tgcatcactt
    13441 tccagtctat cccaaacaat aagttttgca ttaattaaac caacgccaat ctctcctaaa
    13501 cgtttcggtg aatcacctaa aataaatgct tctactgctt gtgttgcttt ctcattggct
    13561 aaccgtaact catatcgatt ataaatacca tatttcgtta atgcttctaa ttctgaaatt
    13621 ttttctcggt tcgcaatttc aaaacgtttc tcataaaaat taaaaaagag aggactcttt
    13681 cgcgatccaa aatacaaaga taatccttca cttcgaaaat agccatcatc taaaaaacaa
    13741 ccgccaatat tctggaatct cttaaagtcc atttctaata aacctgcttt ttgtttttct
    13801 agtaattcaa agagatcgaa atgttcttcc gtttccaatc cccaaagttc atctaacgca
    13861 atatcgaatc ggctacattg cacacgtgta taaccagctt ccaactttcc ttgatttttc
    13921 caaatggaat atagccatgt tcgccaatct gtttgttgtt cacgcatgac ttcctcatat
    13981 tcccggcaac cttgtcctga aaattgcaca agtacatttt ctgttacagt tcgttttgaa
    14041 tgccagaaca cccagatatt cccacgaaca gaaagacagt caaaaagata caagcccgtt
    14101 ggacgtgttt caaattctgt cagatccatt cgtaatacac gttgaatcac tgttttgtag
    14161 tctgtcccaa aaaaggaaag acgcaaataa tcaatcattg ctcgaagatc tattccgctt
    14221 ttcatataca atcgaaagcg ttccttgatt cgttgttcaa aatcctctgg gatttttctt
    14281 ttcccttgtt ccatctttct aatgtaatct tttgagcagc ccatcaattg cgcaaatctt
    14341 gcttgtgata gcggcttttt atctccactt atattatgaa ttgcacttaa cttctttctg
    14401 tagcttttta gctcaatcgg tgtcattttc tcgctccttt tataaaataa caaaatcgat
    14461 ttttttaacc ctttagaaac accgatatat caactagtcc ccctcgtttt ttgggaaaag
    14521 tagtacaact gctgacctta gataatcact tgatacaaaa gggtttataa aacttttttc
    14581 tatgtgttat gttatttctg ccccccatat tatatatcgg ggggctttac acaaagaggc
    14641 cgtgcgcaag cgcacgacct ctttgtgagc tgcacacgct gctagcgagt gcgcattata
    14701 ggcccatgct tcgcagcctt aatgcgcacc gccaggcaga gtgcggctac cagactacgt
    14761 ctagagccct cccgatagat aataactaca aaattaaatg atctaatttt gttatttcac
    14821 tatatttttc aggagaaaaa acgcgataaa ttgacaaagt taaatcctct tctaaatcta
    14881 ctcgataatg atacaatcga gtcaatcgtt ctatatcttt tttcgttagc aatacttgat
    14941 taataacttt tcctgtaaaa acacgttctt tgcgcaaaaa gcggtaatca gttacttgtt
    15001 caatacgatt caaccaatca taaaacgttc tggaagaaag agaaggatta atcattcgta
    15061 ttgctgtagc tactctataa taacaactct ctgccattta acttcacctc cttagttgat
    15121 tacaaaatat gcgcatcaga aaaacttgtt ccttttggat cttttgctaa atacatttgg
    15181 cgctctagtt gttcttgtaa caactgatta tcatctccca tcgtttgatc ttgactatcc
    15241 tcttttactg taaaatcata gacaatcatt tcagtaaatt tctcaaattc tttgataaag
    15301 tgataatctt tgtaaacaaa tggcgcaaaa aactctacag gtacatcaaa tcctggaaaa
    15361 gcatatccac gaccaggttg atctttgttg taaaatggct tatttttaaa atcttctcca
    15421 aaagtcatta aataaccaat gggagacaat cgaccaacag aaatacggaa tgttaaatta
    15481 tcccgaacac cacttggaaa atattctgca tctggtcgtt gcattgctaa aataatgtac
    15541 atccctgctt gacgaccctt taatactaat ggctgaatca atttatcgac tctatttctc
    15601 gcttccatat ccaacgaacc ataaaaagct gcccattcat caaaaaagat aaaatgcggt
    15661 ggtaacccat aataagcata atttttccct ggttcatatt taggatcttt catggttttc
    15721 atataggcat accgttgatt catttctttt aatgcatttc gtaaacaaat aatcatttct
    15781 tcatttattt tgtaaaacac atgtcctttg aatacatcga cgtcacctaa tgctgctaaa
    15841 tctgccgctt ttccatcgca aatatctact gtcccaacac ttaaacaagc ttgaattaaa
    15901 gaatacaata aataggtttt cccaccaccg attgcaccag caatcaacat atttggtgat
    15961 tgatcatata cccaatccaa agttttcatt aaatgaatac gtccattttc tgctatacat
    16021 tgatcaatag gaatccgacc agaatctgaa aggaatacat aattgattcg ggctttttct
    16081 cgttcttcac gaattaaatc acgcaaaaat acttcagata acaaatgacc catttttaaa
    16141 aatcgttcgt gaaaacgccc accatctaaa ggaaaagaaa ccactaattc ttgtttcttt
    16201 tgataaaaat aaacttttgg taatctcatt ttttcccttg tttgtttctc actaacttgt
    16261 ttctttgtat aaacaaaccg attgtcaatt aacattcgaa caagtaactg acgccaataa
    16321 acagaggcaa aatatccttc ttttagtcgc gaccaatgca tcaaccctaa aattaaccca
    16381 ctaaccagca acaaatacaa cacaatactt attccaggaa taagatacat ttgccaattc
    16441 gaaaacgtac ttaaacgtgg ataaaatact ttccaactaa accaacctaa cagaatcaaa
    16501 aatggaaaca aaaagaaacc ataatagcaa aaccataaat aacgattgaa atagcgaatt
    16561 cgccgaccac gatacttgaa aaaatgagct ttcaattgtc acattcctcc tttctgtttt
    16621 tacttttcct gtgctaaaaa cttttgacaa aaagcaacta atacaggaat atcacattta
    16681 gtaaaaaaac ataatcgaaa aagatttaat cgatttttat aagggtgtgc acacatatta
    16741 catattcgta ctatacgaat ccaaatcact tcctgatgat cttgtttcca ctggtacggt
    16801 aatgaaaaac gaacaagatc acgtaaaaac atacactgcc caataaccgc acaaatatat
    16861 gcatttgttt gtacaaaaat cgttggattg tctccaaaat actcaatcaa ttgttggata
    16921 ttttgataac aagcacaatc tctcaaagta tttgattggt tttatctgaa ttcaaaatct
    16981 ccccttcctt ctatcttaga taaaaagaat aggaagactc cttcctattc tttcaaaaaa
    17041 accttatttt ttctcttttt ccttagaatc aacacttggt tgtttttgat ctaaaccttt
    17101 ttcttgtgat tgtttcatat taggattatt tgttggagct tctactttct ctaatccttt
    17161 cgcataaatc actaaatctg aatattcacg attgccatct tgtgctggaa tatataccac
    17221 atgatattct ggatcaatta atttcacagg atcacgtcgt ttaaaaccag tcaaatctac
    17281 atctgctgga aatttaactc gtcgtgcaat ctttggttca tctggatttc caaaaactaa
    17341 ttgtgctcgc tgtgatcgaa tttctcccgt ataatcgcct gtttcattat caaatacacg
    17401 atcagactct tctaatgcgc caaagcgtac ggctcctaaa caagtttcat ctaatgcttc
    17461 tgtaatgtca taattatttg gaaattttaa tcccatctta caaaacctcc ccaattttta
    17521 caccagttaa aaagacacca acatcttgat agccagttgt tcgacgctct gtttgtccca
    17581 tatcatttgt ttcacgacta ttcactcgtt ctttacgaaa aacaaaataa gcttcttcaa
    17641 atgaaatacg cacctctttt tctggtaatc gtaatctttt atcctcttca gctgtgagat
    17701 aaacaaaaaa agcaggctgt tcttctcgcg aacactctgc ttgtaattga acatatcgcc
    17761 cagacacacc attaatttcc tttggtggat taggttcccg tgaacccaat aaaaatactt
    17821 gacctaaaaa ctctttcttc atacgcaatg ctttttctgc cataaagttt ttcctcctct
    17881 taaaaaccaa aataaattct aaatatttct acattacaat caaacaagcg gttaaaaatc
    17941 ctaaccgctt gttcctcatg actaatcttt ggctttacgt actttataaa gtgttatacc
    18001 taaagcaatg actaatacta ctaatccaag aaccataagt atactacttg tttgttcacc
    18061 tgtttttggc aacattggta caacagtagc tggtttaacc cgttgttctg gtttcactgg
    18121 ttgcggtggt tttggcgctt ccacaatttg aaccgtttga tctttgtttg ttagatctac
    18181 attgtgtttc gccacttctt caaacgtttc tttctcatct tccgttttcg cttggagcca
    18241 ttccgcaaaa ctcaagcctt ttcctgcaag attgcgaccg tccactaaga attcaaataa
    18301 gaattccatc atttctttat cggccgcaaa gactttttcc gcatgagtgc cttcaaatgg
    18361 tgtgccgtct ggtgttaagt agccttgaac aattaagcga tagatttgac caatcgcaag
    18421 accgtctact ttgacccatt caagcacagt ttgatttggc aaggccaaga tctcttttcc
    18481 gccattttta ttcgtcgctt tcgtcgtaat ggttggatta ctgattttga tggtttggtc
    18541 attgtcggta atatctgcgt gagaagccaa taatacgcct tctctaaaca gatcttcaaa
    18601 gaccacgact tctttgcctc gcaacgcacg tgcgtctaga ataaagtcta gattgactgt
    18661 accatccgtt gtttctgcca caaacgttaa ggtacttgtg acttcttttc catctactag
    18721 cactggtttt tccgttactt tgtccattag aacaccgttg actgtgtatg tttttccaac
    18781 gaccaaatcg tggtatttca cagcgtctgt aatggtgact ttcgttaatg gattaacctc
    18841 tttcaagcca gtgggtttat gtgtagccgt tgtacgtaca cttgggttag ttactcgtac
    18901 cgtttgccct ttgtcgttga tgtctttatg gtttgctagt tcttcatcat ttctaaaaag
    18961 actttcaaac acgacgattt cacgaccatt tatacctgtc aaatcaaagg taaatggtac
    19021 gatcaccgtt tcattttctg ctttggcaat aaagccaaca ctcgtttcta ccgtatttcc
    19081 atgcacaagc aagggttcac cggttgcttt atccattaag atccctttga ccaagtatgc
    19141 ttttcctgga agaatctcgg taatttcaac ggtatcgttt aaggtaaaca atcctgttgg
    19201 gtctgcgact gtcaatccgt cttcaaagac agccgtggta tgaacggttg gattattcac
    19261 tttcacactt tgggcttcat cgttgatatc cgcatgtgct gcaacttcaa tgccatcacg
    19321 gaaaagtttt tcaaaaacaa cgatcgtttg acctttcaga acactagcat taaccacaaa
    19381 ttcaaggtct tttgtgccat tgactttgtc tgcaataaag gccaaggtac ttgtgatttc
    19441 tttgccatct tgtaaaattg gcgcattcgt tgccttgttc atcaatactc ctgaaatggt
    19501 gtattctttt ccgacaaaca agttggtata agaaacactg tctttaatga cgatcgtttc
    19561 taatggatca accacttttt caccatcggc tttatttgac gcttgtgttt ctagttttgg
    19621 tggaatcaag taattacgta cagaaaccac taacgtttcc ccatcatctg gcgcattttg
    19681 tttgaatgca accgtgaatg cttgtttatc tgtatttggt tggaaacttt ctaatggggc
    19741 attttccaag aagtaatagt catcggcaac tagacctttc actaaaattt ccccgttttg
    19801 atcagtggta tattcaccaa ttgcttgatt tttaccgtta tacaaggtaa agttcacacc
    19861 tgcgagcggc gttttcttct tgttccattc ttcatacttg aataatttta cacttttccg
    19921 tgcttgacgg ttcgcaaaat ggatcacttt gatcggttct gtatcattgg taatcgagaa
    19981 cactaatggg ttttgattca aaacgtaatt tacgggggct ttgatttctt ccaaacgata
    20041 gcgatctttt ccataagtaa gtgtaccgtt agttaggaaa aagccttttt cattggtttt
    20101 aaagatatcc gttgtttctg tatcatttgg aatctccatt gtgacataac gattggctaa
    20161 agtatcaaaa atcttgaatt ctgtattagc aagtggaatc acttttcctg tttcttgatc
    20221 cactttcacc actttaagac gttgttcaat tactttatct tctaaaacat aatggaaagt
    20281 ttgcccattt tcagaaattg tgacttcaag tggttcaaat agtttatacc cttcttttcc
    20341 tttggtttca gaaagaatgt acgtatcaaa gacaacggta tttttaccaa aagtagcata
    20401 accatcattg tctgtcacaa cggttttcac cactttgcca gttgtttttg acgtcaaagt
    20461 gatttcaatg ccagctaatt ttggtttgtt atctggattc gttgaatcga ctaaatcttt
    20521 attagcaact ttcactaaat caatggttcc tttgatcact tgatcttttg cggtcgcatt
    20581 gacagttttt ccaggttcaa caacaatttc aattgcttca tcagaaagca cataaccttt
    20641 tggcgctttg atttctttta aaacatattt gccaggatca agatctttaa tttctgcctg
    20701 tactttgccg ttaatttttt tcaaggtaat ttctttaatc tttttcccat ctgcttgata
    20761 caaaccatag accgcatttt ctaaagaagc tgcaccttgt gctttcacac cagtttccgc
    20821 atcttcttta aacacacgaa tgtttccttg ttttagaatt tgtaaattaa taacagacgc
    20881 attaggttct gttggatgta acacaccaat tgtttgagct cctggacgac gataggctaa
    20941 tggcgcacct tgaactttaa ttttattcaa ttgaattttt gctttatccg gtgcctcttt
    21001 tgtgactgta atccatactt cattgccgtg aatagataca ttgacacctt ttggtttttg
    21061 aatgtctttc acatatttca aaaaatcatt tttattcttt actttcaacg tttcgccaat
    21121 ttttaccgta tgtgtttgat tattaaaagt tgctttttca ccaaagttat taatcaaacg
    21181 ttgaatttct gcttttcgac gatcataatc aacacggata tttttgattg ggatttttgt
    21241 gcccaaagct tcccaaatca taaattgtgc cgcaatgtat tgttcatcgg atttgtcttt
    21301 atttgtgaca tatcctaaat aagagatcaa gcttgttttt ttccgtacat ttgaattttt
    21361 caaatagttt ttcaaagcag tagctgtata aacttgacct tctgcggctg agacaccagg
    21421 ctcaatacaa aacgccactt gtccattaat ctcaaaacga accatataat ttaaagtgaa
    21481 gtttagattg ttcggactag aagtaacacc aatattttcg ccccaatcaa ttttccgacc
    21541 acctaaaaca gctgcattgg ttgcacggcg aacacgaacc gaacgattgg ttggtactgt
    21601 tactaacagt gtaggtgtac ctgtttttgg aatgttctgc tcttttttct tttgattttc
    21661 aatactagcc gtagattctt tgtttggttt cgttggttga ttttgactag ctgcggttga
    21721 agagattgtt ttttcaacgt tttcctcatt ttttccttct ttgtcagcag tagccgctgg
    21781 ttgttccact gtttcttcta ttcgtttctt ttcttccgct tgtttctcag aagactctgg
    21841 ctgcacagaa ggcgttgctt cggcagcttt ttctccttct agagtggacg tttctgaagc
    21901 aggggttgta attgaggcag tttcttcaac tggttgtgaa gtaccaggac tattccctgg
    21961 gtgttgtgtt tccccaatcg tctgatcgag agtcgttttg gaattgaccg ttggcgcttc
    22021 tgtcacaggg gcctgttcaa cagtggcttc accagctggg accccggctt ctgctggttg
    22081 gacttctgtc acttcagaag cgacttgggc aatggcttcc atcgtaggtt gtatagccgt
    22141 cgtttcttct gcatgtgctt gagcagttcc caccaagaaa cagaattgag aaaaagccac
    22201 caatgcgagt gctttcaacc aattcatttt cgtttttgca tacacaagaa ttcctccttt
    22261 tcctgagaat tttatataat aaaacaaaac gccgttacca aaagtgataa cgacgtgaac
    22321 tgtctcttct atttttatct ggcgctctta tctgaacaca tttcatcaat gattttaccc
    22381 tcccactata attacagaac aaaaaaagaa cctgcttcgt ggaaatcaac tgtccatttc
    22441 ccaattggaa taccagcttt tttggcaact tcaccatcac caaatctcat gccataccaa
    22501 ttactacctt catccttaat ttctttccaa ccatatgaca tagcttcatc taatgaatca
    22561 aaaatcatga cactattgcc aattgttaca ggatctggct taagatcttc tggaagagaa
    22621 atatcaatca taccataatg atccgattcc tcagtattat tgtcattact agctactggt
    22681 ttggttgttc tactggctta ttttgataca acaagtactc ttattcttct tttacttctc
    22741 cgttttcaat ttcccattca aaccactccg caaagtcttg cttaaaacca tctactcgat
    22801 acctattttg taaataggca tcttctgacg tcgtaggatc taaataggta ggtttattct
    22861 ctggacgagc atagacacct acccatgttt cgtaatctcc ttcaaaataa ctatctacca
    22921 aatagccttt ttttctaaga atctcccgaa cttgattttt aattattgat acttgttcaa
    22981 aaccatcact cattctatca cctcaaataa ctctagattc tcataaatat tcccgacaat
    23041 ttcaatccta tcaatgatct ctaacaaatc gctacttatg cttccccatt cgtataagaa
    23101 tttcccttcc gcaaaataaa ttttccataa acttcttcat gatcgtccca accaatatca
    23161 ctctcgaaaa attccacgtt gttcttatct tttagctcag taaatgccat aagttcaaca
    23221 tgttttccaa cctcgaaaca atcacaccac ccatcaaccg ttacacgtgt gccttcaata
    23281 cctaagaaac tttgtcctcg tgtattaaac actaaaactt tccgcatttt ttgctcatta
    23341 attaatcacg cgcgaaatct aggaatcaca acttattcgc ttcttcttta taaataaaaa
    23401 aactccaata atcggaaatt actatctttt cctcattcct tttttaaatc ttcatacttc
    23461 ttcttatctt tgtcctaacc taataacaca aattttgaag aaaaactcag taaaacctga
    23521 ttcttttttt atcttcacaa caaccaactt tttcttcaga tccttttact agaacttgta
    23581 tacaaaaatt gttgaatgct gatataattt gcggctactt gaaaaaacga tagatgtaaa
    23641 aagataaata g
//
LOCUS       DAZAOD010000034        23610 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000034 DAZAOD010000000
VERSION     DAZAOD010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.035"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(29..574)
                     /locus_tag="ACHDPO_001376"
     CDS             complement(29..574)
                     /locus_tag="ACHDPO_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFN3369014.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(586..1278)
                     /locus_tag="ACHDPO_001377"
     CDS             complement(586..1278)
                     /locus_tag="ACHDPO_001377"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFN3369015.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1297..1581)
                     /gene="macP"
                     /locus_tag="ACHDPO_001378"
     CDS             complement(1297..1581)
                     /gene="macP"
                     /locus_tag="ACHDPO_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFN3369016.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1594..2157)
                     /locus_tag="ACHDPO_001379"
     CDS             complement(1594..2157)
                     /locus_tag="ACHDPO_001379"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFN3369017.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2385..3047
                     /locus_tag="ACHDPO_001380"
     CDS             2385..3047
                     /locus_tag="ACHDPO_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFN3369018.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3171..4367
                     /locus_tag="ACHDPO_001381"
     CDS             3171..4367
                     /locus_tag="ACHDPO_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFN3369019.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4468..5844)
                     /locus_tag="ACHDPO_001382"
     CDS             complement(4468..5844)
                     /locus_tag="ACHDPO_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFN3369020.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5881..6748)
                     /locus_tag="ACHDPO_001383"
                     /pseudo
     CDS             complement(5881..6748)
                     /locus_tag="ACHDPO_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
     gene            complement(6837..7862)
                     /locus_tag="ACHDPO_001384"
     CDS             complement(6837..7862)
                     /locus_tag="ACHDPO_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFN3369021.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7880..8554)
                     /locus_tag="ACHDPO_001385"
     CDS             complement(7880..8554)
                     /locus_tag="ACHDPO_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFN3369022.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8738..9631)
                     /locus_tag="ACHDPO_001386"
     CDS             complement(8738..9631)
                     /locus_tag="ACHDPO_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFN3369023.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9705..11402)
                     /locus_tag="ACHDPO_001387"
     CDS             complement(9705..11402)
                     /locus_tag="ACHDPO_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFN3369024.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11395..12708)
                     /locus_tag="ACHDPO_001388"
     CDS             complement(11395..12708)
                     /locus_tag="ACHDPO_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFN3369025.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12708..16649)
                     /locus_tag="ACHDPO_001389"
     CDS             complement(12708..16649)
                     /locus_tag="ACHDPO_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFN3369026.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16758..17216)
                     /locus_tag="ACHDPO_001390"
     CDS             complement(16758..17216)
                     /locus_tag="ACHDPO_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFN3369027.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17514..18032)
                     /locus_tag="ACHDPO_001391"
     CDS             complement(17514..18032)
                     /locus_tag="ACHDPO_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFN3369028.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18034..18651)
                     /locus_tag="ACHDPO_001392"
     CDS             complement(18034..18651)
                     /locus_tag="ACHDPO_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFN3369029.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18648..19502)
                     /locus_tag="ACHDPO_001393"
     CDS             complement(18648..19502)
                     /locus_tag="ACHDPO_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369030.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(19499..20410)
                     /locus_tag="ACHDPO_001394"
     CDS             complement(19499..20410)
                     /locus_tag="ACHDPO_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369031.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20451..21785)
                     /locus_tag="ACHDPO_001395"
     CDS             complement(20451..21785)
                     /locus_tag="ACHDPO_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369032.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            21993..22823
                     /locus_tag="ACHDPO_001396"
     CDS             21993..22823
                     /locus_tag="ACHDPO_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFN3369033.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVDGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23067..23316)
                     /locus_tag="ACHDPO_001397"
                     /pseudo
     CDS             complement(23067..23316)
                     /locus_tag="ACHDPO_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6907 a         5143 c         4118 g         7442 t
ORIGIN      
        1 ttttatttta tcaaatcact ttgttttttt ataaaatttc tgcgcctagt gtggactcaa
       61 aatgtctcaa tgcccattca tgtccaacgg gatcgaaact tgccacggaa tctttgaaaa
      121 tatggagttt gtatcctaga ttatacgcat cgactgctgt atgcaacaca cagatatctg
      181 tacatacgcc ggtcaaataa atatctgtga tctggcgttc tcgcaaacgg atgtctagat
      241 ctgttccact aaaagcggaa taatgccgtt tgtctatcca ataaacattt tcctcttgct
      301 catagtcttg gtataaactt tttaaagagc cgtacaattc ccgtccaccc gttcctatca
      361 cattatgcgg aggaaataag cggttctccg gatgaaagga atcttttgga tcatgcgcat
      421 caatggcaaa aacgacaaaa tccttttgat caataaactt ctttgtatga gcagtcagct
      481 ttttttcaat tacttgtcct gctgtcccag tagtcagctt tccatcctct gcaacaaaat
      541 catatgtgta gtcaatcgag atcaatgcgt tcatcttagt cctccttata cgagatgttt
      601 gacaaattcg atcaccattt ctgctgatcg tttgcctgcg tcttcgataa attcgtcaaa
      661 gctttgtgtc gccgagtgat ctgctgtgtc gctcattgca cgtacgatca aaaatgggat
      721 attgaactga cgagctgttt gtccaacagc ggctccttcc atttcgcaag ctaatgcttc
      781 agggaaattc gttaagattt ctttgatttt atctggcgag tcgacaaatg tatcacctgt
      841 aacgatcaat ccttcttttg cgttcaaatt cgttgctttt gctgctttaa ccatttcact
      901 gcgcaaatat gtgcttgctt cataatatag aggcattcct ggtaattgtc ctgggttgta
      961 gccaaatcct gttgcatctg catcaaaata agctactttg tctgatataa cgatgtcacc
     1021 tacttgtaag ccttcaccga ttccgccagc tgaacctgta ttgatcacca tgttcacgcc
     1081 gtattgttgg atcaacagac ttgtggtaat agatgctaag acttttccta taccggaacg
     1141 tacgacgatc acttcgtggt tacctaatga acctgaaata aataaagcgc ctgcgcgttc
     1201 ccatgataat ggttcgctta ggttctctct caaaattttt acttcttctt ccattgcgcc
     1261 gataataccg attttcatct ttttaattcc ttctttctat ataaatgcga ttgctaaaaa
     1321 aaccacacat aacattagga taacaataat aagagatttc atcaaaaaag agttccattt
     1381 ggtcgtcttt tcccgttcgc tgatccttgt tttcgtgatt ggtttattct ttttgctttc
     1441 tttacgataa aagctggcaa tctttttttc ttcttgctga taagctgttt ctgcttttcg
     1501 ctgttttttt aatgactcgc ttgcttgtgc ttgttgtcgc ttgcgaagtt cgcttcgcgt
     1561 aataagcggt cctttggcca taagccgatc cctctacttt cctttggtca atagttccca
     1621 gtattgaatc gcataaatcg tctttgcatc acaaatcaac tgatctttca tcgcttgttg
     1681 cgcctcttca agagttagat gatacaactc cagtacttcg tcttcatctt gtgctaaagg
     1741 attctcgacc ttctctaccc cttgtgcatg ataaatatga aggacttcat ttgcaaaacc
     1801 tggtgaaaga tacatcgaag taagatggct cagcgacttc gcacgatagc cagtttcttc
     1861 ttctaattct ctagctgctg tcatttcggg attttgtcct tctcctggat cgatttttcc
     1921 agctggaatc tccaaaatca ctttttctaa aggttttcga aattgtttga caagaagcag
     1981 acgatcttgt tcgtcaaaag caatgatccc gacaccgcca ggatgaaata ccagttctct
     2041 cttcgaagtt cctccatctg gcaaacgaac ttcgtctaca gcaacatcaa taatttttcc
     2101 gctatagatt tctttgcgac tgattgtttt ttcttcaaat tgctcattgt tcagcatatc
     2161 ttctcctgct ttctttgtaa tcataactgc ttttttttca tttttcaatt tttctcaaaa
     2221 actccttatt agtttaccat agataaacct tagattttct ctaaatatag aaaatccttc
     2281 tttagtccga tactctttct agtagtccgt atgctaaaat aagtatgtaa tcgaataacg
     2341 aaaagaattc aatactcaac gataaatgac atggagggtt tattatgata aaacgaaatt
     2401 ggccgtggct tctagcattg gtcttgctat ttctctttgt ccgaaacaat agtttttctt
     2461 ttgttctagg acttttattg ataggtgtag ttttagtttt gtggggactc tttggttcgc
     2521 gcaggaaaaa gggaaaacaa gaagaaattc ctgcactgac tgacgaactt gaaactcact
     2581 atgaaaaaag cggtatgaca gcgaatgaaa tttcattttt tcgacaaaca atgaatcaaa
     2641 caaaaaatga gatcaatcaa ttgcaaatga atatgcagca gacagccaaa cttaaagcaa
     2701 tcgatctccg ccatgatcca gtcaaagcag cgaaagcttt attcaaagaa ttggtgaaag
     2761 aaccaaaccg actgcatgaa gcaagtcagt ttctttatac gcatctgccg aatctagttg
     2821 atttgacaaa taagtataat gagatcaatg accatgagat caaaaacaaa cagacctatg
     2881 aaaaactaga agaaagcgcg cagatcatcg accagctgtc agctttaatc gcacaagatt
     2941 atcaaaaatt cgttgctgag gatctagatg atatcgacgt agagatatct gttgcgaaac
     3001 agagcttaaa gcgtgataat aaatatgaac cagaacaaaa ggattaactc ttttgttcat
     3061 aaaagaagac tcggaacatt cagatgatgt ctggctgttt cgagtacttt ttctaaagta
     3121 gagacattca tgtaagaatc gagaacagat tcaacaagga ggaatttttt atggatcata
     3181 aaccgactga aacaaaagat gttacaccag ttaacgatac acttgaagat ttattgaaca
     3241 acccgttttc aactccaaca gatacgctga ccacttcaca acaagcggag attgatcagc
     3301 tccaagagca acagacagct gctcgtttaa ttgacaaact accggcggaa cgccaagaac
     3361 aagctaaaca gctagcagca aaaatcgatg ctaatgatgc acagtctgtc atcagctacg
     3421 gatcggctgc ccaagcaaaa ttaagtgaat tctcacaatc gatgttgaat catgtgcaag
     3481 cacaagatat tggtcctgta ggagattcct taactgaact gatgtatcgt ctccaagaag
     3541 ccaatcctga cgaactgcgt gccggagaag ggaacatctt ccagcgtgtc ttcgggaagg
     3601 tcaaacaatc gatctatgaa gtgacagcaa aatatcaaaa gattggtgca caaattgaca
     3661 agatttcagt gaaattagat aaagaaaaag acggtctgct aaaagataat ctgatgttag
     3721 aacagcttta ccagaaaaac aaagactact ttgatgcact gaatatttat atcgctgctg
     3781 gagaattgaa aatggaagaa cttcaaacaa cgatcattcc agaagcgatg aaaagagcag
     3841 aagaaactgg cgatcagatg gatgttcaga ttgccaatga ttacacgcaa ttcctagatc
     3901 gtctggataa acgtacgcat gatcttcgct tagctagaca gatcacgatc cagcaagcac
     3961 cacaaatccg tttgatccaa aacacaaatc aggccttggc tgaaaagatc caagcatcta
     4021 tcgctacagc cattccgctg tggaaaaacc aagtcgtgat cgcattgacc ttgcttcgtc
     4081 aaaaagatgc agtaactgct caacgccaag tctctgaaac aacaaacgac ttattgaaga
     4141 aaaattcaga aatgctgaaa atctcagcca tcgaaacagc gaaagaaaat gaacgtggaa
     4201 tcgtggatat cgagaccctt caaaccactc aaaatgattt gatcgaaaca atccaagaga
     4261 cattgcgtat ccaaaaagaa ggaaaagaaa aacgtcgtca tgcagaagta gagcttggac
     4321 acatggaaga agatctgaaa caaaaactgt tggatttaac ccaatagatc acctttcgct
     4381 tgttactaaa acaaacgccc aacaacagtt tattacaact gttgatgggc gtttttctta
     4441 tctttcttct aacttctcca ttggagtcta tttctcattc atcttgctgt gtccatagcc
     4501 atagccaaaa taaatgatca gtccaataac cattacgata ccgaacacga tccatgtcac
     4561 agtttgcaga cgaagcatca atacaataca agtcaaaatg gagacgattg gcaatagcgg
     4621 aacgaatggc actttgaatt ctccagcttt tggtttgcca aacatttttc tcaacttcag
     4681 taagcctaga ctaacaagca tcaaataggc gagcgccatg atattcgtta gttccgctaa
     4741 tacattcaat gggaaaaatc cggcaaagaa tacagctgcc acaccagcgg cataagtcgc
     4801 ttttttcggt gtacgatgct tttgatcgat ttctgtcata aacttaggaa gtaagccatc
     4861 cttgctgaca gcaaacagta aacgagcaag tgaatacatc atcgagatcg ttaccgtcag
     4921 tagcgttaaa attgccccta cagcgatcac cgcgcccact gttccatgtc ctacatacct
     4981 cattgcaaaa gccactgggt cattgactcc tagttcagta tacggaacga ttcctgtcaa
     5041 gatcagcgtc acgatgatgt aaaggacagt agcaatcagt atcgaaccaa tgattcctct
     5101 tggcacatct ttttgcgggt ttttgacttc ctcggctgcc attgcaacgg catcaaatcc
     5161 caagaaagca aaaaacacaa gagctgcacc atctagcaca ccggaaaaac caaaaggcat
     5221 gaatggctgc cagttatcag gtttaacgaa aaatattcct acaatgataa acaacgcgat
     5281 gataccaaat ttgacatata ccatggcatt attcaaacgt aatgctttct tggcttcaag
     5341 cgacacgatg taagtgacga atatcactac gagcaccgca atcaagtcaa tgtatgtacc
     5401 attttccgga ttgtacccgc cagttaatgc ttgtggaagt tcggccccta aacttttcaa
     5461 aaaaccttgc atatagccag accatccgga agcaacagag gaaaccgcta gtaaaaattc
     5521 cccgatcaac aaccaccctg tcagccaggc agcaaattca ccaaatacaa catacagata
     5581 ggcatatggc ccaccaatca ctggcactcg cgaagcaaat tctgcgaaac ttagtccaga
     5641 caaaatgaca acgattgcag ctaagacaaa tgaaagtgac agtgctggac cagcattttg
     5701 attggccgca acccctgtca ccacaaatat tcccgtaccg atgatcgcac caattccaag
     5761 catgatcaaa tcagacgttt ttagttcttt tttcatctca ctcgtatgat tgagattgat
     5821 ctctttctta cgaaacaaat ccattgaagt tcctccccat tttaggttgg aaaacagcga
     5881 ttaaactgtt ttcatatacc ctaaaaggga taccacctaa aatgactaaa aggcaaccaa
     5941 caataacata aatgagctct tttttcgttt ttctttcgcc aaggatgaaa atcccaccta
     6001 aagtagagat aatgatcccc atttgtgaaa gtgagaagcc aacagctaaa ccaagtgatt
     6061 tgactgttag aagcatgcag atgtttccta agccccataa taatccacag atcatgtttt
     6121 tccacacaaa ctgatcgact ttaactttac ggaaagcaaa gaagcttgcg cctaagatca
     6181 ttccgatact ttgaggtaag ataattgaca tcgcatccaa attcgcccag ttgacgatga
     6241 tggtatatac accataacca atcgtagaga agatcaatgc tctaaaaccc ttaccaaaat
     6301 caagcatttt attatctgta tctatttttc cttcgtcatc ttgtcgggca gtcaaatacg
     6361 caccgcttac aagaagagct aaagcaataa taccgtatac ataatctttc gtttgtgtcc
     6421 attcatggaa gaaaacggct cccgcaatcg tattcaaaat taattgaaaa ccagtagaca
     6481 atggtagccc tacagaaaca cccatgtact tcattccatg gaactgtcca ttttgtccaa
     6541 cactccaagc taagccggat aaaaatccga tcaagaaaat ccaaggggtg attacaggac
     6601 taacaacgaa aaagacaact aaagaaaaca gaaatgcacc gatcgtcatt cctagtgttt
     6661 gttgattggc atcgccacca attttaccac ttactaaacc aatactaccc catgccaaca
     6721 tagggactaa tgctattaaa atttccataa ccaatctcct tttatttcac atgataagaa
     6781 acttatcagc gaaaacgtta acaacacaag cacttttttt cgtttctaac gattttctaa
     6841 cgtttttcat tataaaaatt taagattggg aaaaataaag tcattgttgt cccttttcct
     6901 tcagttgatt cagccgtcaa atggatacct aatttttcgg ccagattttt tgctaaataa
     6961 agtcctaatc ctgttgaatg tgttttgcta agtcgaccat ttctcccagt aaatccctta
     7021 tcaaagatcc gtttcaagtc ttccgctggg ataccgatcc ctgaatcttt aactgaaagg
     7081 ctgactcctt gcgcttcctt ttctatgctc acaatgatgt ttccgtgatc cggcgtatat
     7141 ttgatggcat tactaagcaa ttggttgaag ataaaagcga tccatttagc atcggtcaaa
     7201 acagtatgat cctcaccaac gatctcgtag cgaatatttt tttggataaa ataatttgcc
     7261 tgactgcgta tcacaggctg aatgattcct tttagtccat attcttggat gaggtagtcc
     7321 cgcgagaaac tgtcgagtct tgcataatac aaaacttgtt ctacgtattc atcgattttt
     7381 gataattcat tttctagtaa tgtatacttt tgatcgtcaa tatcgaactc gatcgaacga
     7441 actagcaatt tagaagcgga aagtggcact ttgatttcat ggacccatga gtcaatataa
     7501 tctttttggt cttgttgatt actgattgct gattgcatta cttcttggtg ttcacggatc
     7561 agctgattga tatattcttc taccagtttt tcttcttctg tcctcccacc actcaaataa
     7621 ttttgcaaag gggaagtttt ttgtatgtcg gctaattttc cccaccatct tctcttgctc
     7681 aagtaaccac ccagcagata aaaaatcaga aagacgccct caatcaaagc taaataagca
     7741 attgtgctca aatcaacttt gatgtttggc gccagccaca tcacaaagat cgtcaatgca
     7801 ataaaaaaca gccatcccaa gatcaatgtc cactgatctt tcaaatattt aaaaaaattc
     7861 atcttaaccg ctcatccttt cagggaacga tatatccctg tcctactttt gtttcgatat
     7921 atccttggat acctgcctgt tcgatttttc ggcgtaaccg attgatgttg actgtcaatg
     7981 tattgtcatc tacaaatcgt tcgtcatccc acagtgctcg cagcaatttt tcccgactta
     8041 agatctttcc attgtgcttc atcaaaataa ataatagacg atattcattt ttgctcaaat
     8101 caatgatctc tccgttgatt tccatacttc cgttgtcaac attcaacgta atgccattgt
     8161 ggctcatcat ttcactagat aattctgtgt agttgtaaga acggcgaagt aatgcattga
     8221 tttttgcaat cagtacatcg atttggaaat gttttgtcac aaaatcatct gcccccatgt
     8281 tcatagccat gatcatatcc atattcgtat tcctgctgga gataaaaatg atcggtactt
     8341 tcgatacttc acgtattttt tgacaccaat aatagccatc caaaacggga agattaatat
     8401 ctagtaatac aagctgtggt tcttctcttt caaagtctga gaacacttga ttgaaatcgg
     8461 tcgttccaaa ggtttcaaat tgccatttct caagttcctc catgatcaat tgtcgaatga
     8521 tctcttcgtc ttcgactacc atgatttttg ccataaaaaa tccctccatc tttcttcttg
     8581 ctactacaat atcaaagaag cccttgtgaa acaagttggc ttacctggaa aatgtcattt
     8641 tagcaaacgt taaaaaaaac tggaaatatg cgatttaatc gcgtttgtct cttccaagca
     8701 gcttaaattt attatgttat tcttaataat tggtctatta tctgttattt ttctttcgtt
     8761 gtttttgtct tttaaatttt cgataacacc aataaccgaa aagcgttagc actagcaata
     8821 tacctagaag gagtataagt aatcgataaa gatggtattt ttttgtctgt tctatctttg
     8881 aagagacttc ttctgtaaag ggaactcgtc ttcctgtcac tagtaatcgg tgagtgttca
     8941 cggtgtaagg tgtacaagtg ataagtgtga ctagatcctg cttttctcta attgctaatg
     9001 tatttgtttt tgttggaagg acaacaattt tctcaacgac ttcataagcg agcatccgac
     9061 catacacttc aagatagaat cggtcatctt gctccatttc ttcaagatcc gtaaagagtt
     9121 ttttctcagc aataccgcta tgggcggtaa tcacggaatg tgtactctct cctccagttg
     9181 gaaaagaggt gccttgcagg actgtcgctc ctctatctaa caaaagatca ttcgtttcat
     9241 caaataaagg caagctaaca ttgattttcg gaatatagat ggctccgatc atatgttgtt
     9301 cgtaatattc ttttcctgga ttttggacat ttctaaccgc ttgctcaaaa ggatctttga
     9361 cttgtcccat tcctgggatt actgatgtat gagcaagcgt ctgatttttc ttttcatgca
     9421 ctgctaattg ttgctcatgt ttttcttctt tatcgcgttc aagctgcttt tgataattct
     9481 cgatccttct ttgatccaaa taattgctga gagcatctgc taaaaatgga tatgtaaaaa
     9541 ctgcagctcc ggcaagaaac atcactgcca taaataattg taataaaaga ctgatttggg
     9601 tttgaggtct attacctatt ttctttttca ttttcttcac cttcttattt aaaaaaactg
     9661 cagcaacctt tataaaaccg attgctgcag cttatttttg ttgcttatac ttcagacttc
     9721 attttagatt tacggtacca gctgtacgct ccaatcatca aacttattcc gattagtaag
     9781 aatgccaaga gcccgttccc accagtagca ggaagtgacc cgcgtttcat attcggtact
     9841 ctttctggcc ctggattttc tactcctacg atctgaattt cttcattata gcttccataa
     9901 gagatgataa attcagtaaa ggctgcctca cctgttggaa gtacataacc ttctggcgcc
     9961 atggtctctt tcatttgata ggttccataa tctaaccctt gaacctcaaa gtatccattt
    10021 ccatctgcga caaattctgt tgcttgtccg cttgttgccc actcaattct atctgctcct
    10081 gattcataaa cagctaaagg cgactcccct ttataaaata ttgcgtattc agaacggtct
    10141 tcattccaca attcgaatct tgcatcttta agcaattcac tgcttgatgc atcatatttt
    10201 tcaaactttc ttccacctgt tgtgactttc tctggcggct ctactccttc ttcataatca
    10261 aattcatcat ttcgtccgat ttcaataacc gctgtgttgt tatggaaatc atccgcttct
    10321 agttctgtgg aaaccttcaa attatacgtg atcgttaaat ctcctccacg tgcatctgct
    10381 aatctaccta aagtatctac tttggctact ccattttctt ctgtcaaaat cgtcacgaca
    10441 aacccgttgc ttactacttc tactatataa tcttgtcctt ttgttaaaat cgtctcgccg
    10501 gctcgcactt ctatttcctg atcataataa gttagaccaa ctgtaggcgt atctgtgatt
    10561 ttgtaatttt tgataacagc gcttccgttt tcaaggacag aatcgatgaa ataaggaata
    10621 ggtgctgtga tcgtgtaaga agccgttttt cctctttcta gatcaatata agaaatcgtt
    10681 tcttgttctc cagcttcatt aataatcgtt acttgtctaa ggtcgctttc ctctacattc
    10741 atctgtttat ctgcttctct gatttcgttt ttcggataca aatgcacatc tgtattgtat
    10801 gtgtctttcc atgtagaacc atcccacacg ccatccacca tatcaggcat catcactggc
    10861 atcataacaa ccattggaga cgcgattctg gaaatatgag ctggcgaata agtttctaag
    10921 aaaagataga ctttatctct agaagaaggt gcttcttccg tcacttggac ggtagagaat
    10981 accgcttctc cagcttcatt cgttgtttgt ttgtcaatac ttgtcagtcg atattttaaa
    11041 aaccaacttt ctgtgtgccg tttttgaatc cattcaatcg cttcggcaga attaagaccg
    11101 tcttctcgtt ccggtgttaa aggattatct cgaatcaaat cgtaatatac ttccgttacg
    11161 tcaaacaaat caaaatcgac tcctggaata ttttcttcac caaaatccgt agaaaccaat
    11221 ccgctattcg gtcgttcttc cggaacagat gagaaacctt ttttgtgtaa tgtaatcgtc
    11281 acttcacttg gtttttgtgc gacttcttcg gctttgacta gttttccgtt cccgaaaatc
    11341 cctattcccg cagtaacgag taacagtaca ctcattcccg tgacaatcat ttttttattc
    11401 atttttttct ccccgttctt tttttattaa taaaacagca cctaacaata aaagaattcc
    11461 tagtaaagaa atcaacgttc ttgcttcatt cgtttgcggg aatacggacc attttcctga
    11521 ttgacctgga ttgcttggac cactcggctc tttcggtttg tccgttgttt cttttacggt
    11581 ctcgttataa acacgtggtg ttgcggattc ataggcagag actggaactt tcccggattc
    11641 taattcagcc atctcctgtc cgttaactac tacatattgt ggttggcctt ttgcatccac
    11701 ccaaaattca gggatgatga cctcgattct cttacttgct tcatccatct cgtaaccttc
    11761 cacacctttt aattcttcaa aataataggt gccagaaggc aagaaacgtt gtcctgtcgt
    11821 aacaaggccc tctttatccg aaatgaattt gcttacattt ttgtcattca aaggatcatt
    11881 gtctgctggt ttgatccatt gatttttcaa gtcattagca ggagccatat ctaaataata
    11941 tttcccccct tctatcatct gatatagagc aaaaacagca ccttctaatg gttttccttt
    12001 ttcagttgtt cctctttgac gtccatactt gaagaagtat ggatctctta gataaccgac
    12061 atttttagga tagatatgaa tctcttgcag ttcctcggtt gattctgtcg ggtgataaat
    12121 tggcaaaata gcagcaattg ggatagctgt ctgatcgata tcaacatcca atccaacttc
    12181 tggatcaatc gattcttcga aaatcaaata aactgcatcc cgatcttggt ttttcttagg
    12241 tgctttgata cgtgcaatcc cgtctcctaa tccgccaacc gtatctttcc cagttgttac
    12301 cgaagtccct atttggacaa gcctttcttc tgtgattagc tgacggatat tgtttctgtt
    12361 cgtttcagcg atttgctgga cgaattcttt aggagtcatg ttttcagcag cttttttttc
    12421 atgataataa tcggtcatgt cgtaaatggc aaatgtcgct ccatttagtg gcaccgtctg
    12481 tgaaatgata tctgctgttt cccctgcttc ctcagagata gccaagccat cattttcatg
    12541 gtattcaaat tgatcgttat aatcgatatc tcgaatcatc cgtttatgca acacgaattc
    12601 cacgacatct tcccctgatt cttctgccga catcgcatgt ggaagaagga ctgctgcaag
    12661 cggtagtaaa acaagtaatt gaagcatcaa acacaacagc tttttcatta ccttgctccc
    12721 tcctttttag attgtctgac aaacaaacca taggctgctc ctgcaagcgc catgaagaat
    12781 gcagcaagca ggatatagaa taatcgtccg gatcctcctg tagcaggcaa cggattttca
    12841 ggatcgttcc cgacactaag ctgtaatctg attcgatttg tctccaaaag ttcatattct
    12901 aactcttgct gtagatcagg cgtctctgct tcttcgtttg gataatacga aatctcaact
    12961 tttagtgtac ccgcttcttt tcctggaact acccgatcat tttctatgtc aggttcttct
    13021 cgataactaa tttctaaaat aaagtaacct ggaagttttc tatagctgtc aggtgacttc
    13081 acttccttga tccgatagac cccttccaac aagtctgaag cattgaatag ggaagaatcg
    13141 tttggatctg gtgccaagcc tccctcgatg atttcatact ctcctgcact attttgtttc
    13201 tcaattgaaa attctgcgcc ttcaagacgt cggctattca tactgtcaat tttcaaaagt
    13261 tccaaatcga ttggcgctag ttcatcttct aaggttactt gtagtacacc atcgatgatt
    13321 tcatagcctt ccggcaaggg agcagtttcg tcttcgatga ccgtatcttc aatgataaac
    13381 ttaccttctt cattcagtgc aaactggaac acttgatcag atagccgata cccatttggt
    13441 gcgacagatt ccgagacctc atattcacca atagacagat gcagaggttg gtcgtaattt
    13501 aaatcgacat acttttctac tcctacggca cgagaataga agtatccgat cccaggcaaa
    13561 cgtttcgatt cttctggttc taacggatta ccagtgtatg ctcgatacag cgggaaggaa
    13621 gaatccccca ctttcctgat atcgaaacct gcaccatcta atgtatggcc ttcatggtct
    13681 aattttctaa ctcggatctc ccgataatca aacgtattgt aagcagtgaa tgctacccat
    13741 aaacgatcct cttcatctgt tgtatacgtg agatattgcc aattttcttc acctgtttgc
    13801 ttgagttgga tagtccctat agcattatcg taaagtcgca agatccatgt gtcattttca
    13861 tcaggttctt tgaaaccttc tgggttctgg ctctcaatga ttttgtattc tgcatagttg
    13921 gtagtttctt cactatcctt ataaacaaat gaatctggct ctccgattgg atgaataact
    13981 ttctcaccat ccacgattac atatttcccg tcttcatcta ctgaatagaa cgtgagtctc
    14041 cctttctctt cctctacttc gttcacacca gaaagccctt tcgctactgg atatccgatt
    14101 tccagtccgt taccatctgt ttcataaagt tcaaactctg cgccattgat tggcatatta
    14161 ctgccttcaa ttagtttatt gatattcatg tggattggct tgaattcatt tcgcatttcc
    14221 agtttgacat acaactcatc atactctgtg ccttctatgt taggctcttg tacaacagaa
    14281 agcttgtgat attctccttc ataataggaa ttcggatctt taccttccgg tccgccgact
    14341 ctcgaaccag atgtatattc atctacaagc tcgtagtgac ctaacatctc atcttcgttg
    14401 gctgcatatt ttttgatttg gaattgatac gtctcatcta ctaactgata acgtggtggt
    14461 ccagcgatct ctctgatcca aaatatgtcg ctgactgctc cagtttcatc tcctaaaatc
    14521 ggcatcttcg tttcaaagat cgctattccg tccgtggtag ttttacttgt ttcgattggt
    14581 tcggcttccc cactctctgg attttggtca tataatgcaa attcgactcc agccaacggc
    14641 tcgccatttt gacccttctt gctgacttgg aaattacggc ctttatgttc gtaacgaatg
    14701 gaagaagatg ggaaatacat ccgtccagta gtgatatcat tctcataatc ctccaggttc
    14761 tgaatatagg ccatattgtt cactgtgcaa aaatttccgt cttgagctcc cgcatcaagt
    14821 tttacttggt acttgatcct gaccatttcc ccttcaccta aagaaatcgg agaaaattta
    14881 taagcttggt tttcccgtcc gacatacgtt gtcggagtcg ccactacttc tggtggggct
    14941 tgtccatgac gttcttcatc ccatatttct ggctcttggt acttcatgcc gttttctcct
    15001 ggatctagat ggtaaaactg aatatctgcc gatctgccag ctccaaatgg tgagacatta
    15061 aaaccagttt catcataaag tgtggcttgc tggatcgttc tcttgaaggt agaagagata
    15121 tcctccaagg ctgtaacaat gtcattcttg ttgttcgcat tgtaatatcg cggtgttacg
    15181 ccatcttctt ctaaatcagc aatatttttc aatacatttc gtccaatagc atctagtcgt
    15241 tgtctcccgc taacgtttcc atcgattcct aaaccaatgg agaagatact tggcgggttc
    15301 tcttgatact tgtttttcag ccaatgatga taagcaactg tgttgatcgc agatgacttt
    15361 tcttgcgaag taggactgcc attcgtattg ttattagaag aaccatcacc aacccagtga
    15421 gtcgctttat tatctccttc ttttacctct ccataacgat agtgtacatt tacttcatct
    15481 tctggacggt taaagtcaga tgcataggta actggatgag taaaccctgc attagaagta
    15541 ttcccagaaa actcctcaaa atttctgaac aaaacgtcat tatcttcagc aatcttatct
    15601 tccatcacag tccagttgct ccaagctcca ttagtgctcg tacgataact tgactgaatc
    15661 ggtgcataac tgaaggtcgg tgtcccatct cccacaacga ttaggatttt ttctggattt
    15721 ctattttctc cgccattgtc tttatacaat gtttcatagc catttttaag ccctagtgta
    15781 agcggagttc ctccgattgg tgtacgattt aatgctgtat tctcacttcc cgtcaaacga
    15841 ttgatatcat ttgtcaatgg aaagatgtcc gaactgattt gctcatggtt attgatagct
    15901 gtactattat ggtaaaaatt caccataccg attcgaatat ccagactcgg gtcagagagc
    15961 agatctttac tcatttcgtt tactgcctca atcaacgcag catttttagt ttgactattg
    16021 gtcccagcgg ttaattcact catactcgct gacttatcta gaacaaaaac gatatcgatt
    16081 ggactgattt cctttttctc gcccccgatg acatctagat agacattgta aagggttgtt
    16141 gcatcttcag gatgtagatc agatgctgtg ctgcttggca gaacaggttc tacccatttt
    16201 ttgatgtacg ccccgttata atccaagtaa ctgttttcaa aattccgttc atttccccaa
    16261 agctgaacgg tttgagctgg aacgtttcta tcttcttcgc ctgcagttga tccattatta
    16321 gtagcatagt cgtaatttcg ccagttcgct cccccgtttg tataatcact atcatcgatc
    16381 aagttctctc cgtcatatgg cgagcctttg tctccttgat agcgttcatt gctttgtgtc
    16441 caatttccta acacttttgt atagtcattc gttgtaaact tcgggtagcg atgctgttcg
    16501 ttttcaactt ctccgctagg atagatatat tcataggggt cttgcgtagc tgttggccca
    16561 agacgctcca aaataccgtt gaataactgg cgttgaatgc gctggagtgc ttgaccgctg
    16621 ggtacgattg gttcgtccag cttttccatc tcattttctt cgctacgttg aatttcagcg
    16681 gaatcttctg tatcagtttc attttcttgt aattcttggt tatctattct ttcatcaacc
    16741 accacttgaa gaggtagtta cccttcgttc acatcgggga tcttttctgt ttcaaaaatc
    16801 aatgtgccgg tttctgcttc ttttgaataa acttttccga cataccattc ttgaccatcg
    16861 atcgtctcga cttttaggtc ttctccatct tcatcatagg aggatagacc tgttccacga
    16921 acgtttttta cggtaccaat cccggcggct gccgcatcga ttgctaaacg tattctacct
    16981 tcattggcac tttccttttt ttcaaaagcc agatgccatt caagggtttc ttctttttca
    17041 atatacttcc cttcaatttt tgcatagtcc tcatctaaga atacctcatc ctcctttgtt
    17101 tctgttgact cagcagctac atccagggtc gtcatatgat agactgactg gaaatatggt
    17161 ccaaatagca aactgacagt tactaactgc aaaagcttca attttaaccc tttcacatcc
    17221 ttatactcct ttcaaaaata tttgtcttct ttcacaacaa tcaacaaaac aatgcccatc
    17281 taattataat ttaatttaat tttaatttta aatcaaatga tatccttttt agttaaaaaa
    17341 caccaattat acaacattta ttattaaaat taaattataa aattttataa cgttctcatt
    17401 taacaaaact taagttatta agacaaatga ataaacaact acgctttcct cgaaacaaaa
    17461 aaataaagca caaatgcgca tttacgcact catgctttat tcgtacaatt aattcagata
    17521 acggcagcgc ataggatgcc aataacactt cctaaaatag ctcctcctaa aatgtcagta
    17581 ggataatgta aaagtaaaaa aatcctcgaa taagcgatca aacaagcaaa taaaaaggct
    17641 aatattcctg caactggact taattcgaac aacgcagcta ctgataaaaa ggctagcgct
    17701 gtatgtcctg aaggaaaaga agaagtcttc ggtttacttg tgtaaaggac aagccgacga
    17761 tttttttcat aaggtctttt ccgtcttgtc gtttttttga taaaaagcaa accaacaaaa
    17821 aaatagatca aactgccgat aagaatggct agaccatatt ctctagtatc aggtatcaag
    17881 actaaaacag cagcaaggag caaccaaata aaaccaccat tagagatatt actgataaat
    17941 ttcaaaaaat tgatttttcg actatccgtt ttccgttgct tggcgaactt gttgataata
    18001 ctatcatcga ttttagcaat caaacgcaac atgttattcc tcctttttaa gaaccttttc
    18061 ttgcgtacga tggataaaaa gcaggacttg aaaataaaac aagaaactga aacctaataa
    18121 agcaaaatag attggtcctg caaaccagaa tgcgacaaga aggatcaacg tgcctgccaa
    18181 atagaaaagc gcgcttttga aatcattaaa aaacaagaaa aatgcagtaa tccaagaagc
    18241 ttctttttgt tccagttgaa gcaagatttt gtaactaaag agaagcgcgc ttaatagaag
    18301 caaaaacaac gtagtataca tcaatgtata gccaattccc ccaccccaat agcggaaaat
    18361 ctgataatcg atcaatagaa gaagaaaata aacacttgct aaactatctt gctttccata
    18421 aagagagaag ttctcacgaa actttttcca gaatagtgaa ccgagctttt tctcttcatt
    18481 ttttttgtaa tgataaatca tatacagaac tgttcgactt gcagttccta atgtgaaaac
    18541 aggcaagacg cacaggaacc atagtagctg taaatggata agacgtggaa tccattcaat
    18601 gatttctaag aaataatcat tggctttttt accaatcgat cgattcatca tccttttgaa
    18661 cctcctgtca aatccatccc ttcaatgaaa taacgttgtg caaaaaagaa cagcaaaatc
    18721 gtcgggatca agacaagtgt tgctcctgcc atcagataat tccattgtgt cgttgcttgg
    18781 ttctgaaaaa cttgcaagcc aatctgtaac gtgtattttt cttgatcttg gatatataac
    18841 agaggaccta agaaatcatt ccaagctgcg ttgaaggaat tgatcgcaat ggtaatcaag
    18901 gcaggtttcg tcaatggaag catcaaatga ctccaaatat acaaatgatt cgctccgtcg
    18961 atttcagcag cttcgatcaa ttcattattg atcgataagt aaaattgacg catcagaaat
    19021 atattgaacg cattgccgaa gaacgatgga acgatcaggg gcaaataagt acctacccag
    19081 ccgatcttgg agaataatac atattgaggg atcatcgtta caaaccccgg gatcatcatc
    19141 gtagaaagaa ccaaagcaaa catcagcttt ttcccaggaa aatcaagctt cgcaaatcca
    19201 taagcaataa aagaatttga aaggacatta ccgatcacta ctagcacagt gatgaataat
    19261 gtatttcttg catagcgcca aaaaggaaag gcggcaatcg tatccagata gttttcccat
    19321 acgatttttt ctgggaaaaa ggtcggagga taacgaacga tttcttccat tggtttcaat
    19381 gaagtaaaca ccatccaaag caatggaatg atcaaaatga ttcctattac tgtcatgagg
    19441 acataactta gtattttttt tgtttgccga ttcacactgg tctttttgaa ataatccatc
    19501 atttgccgtc acctccagaa taatagaccc acttaggtgc aagcttcaaa ttgacaaacg
    19561 tcagaaccaa cacgatcaga aacaggatca ttgacatagc catcgcataa cccatatcaa
    19621 aagctacgaa cgccttgttc cacatatgca gattataaaa aagcaaagaa tttgcaggtc
    19681 cgcctgttcc atttttcgtc atgacataag cttcttgaaa aatttggaaa gaaccgatcg
    19741 tagaggtgat cacatcgtaa aaaataatag gagtgattaa tggcaaagta atacttttga
    19801 actttcccca aacgcctgct ccatcgattt ctgctgattc atataaagat ctaggaacat
    19861 tttgtaatgt agctaagtaa agtagcattg ctcctccaga actccatatt ttcatcaaaa
    19921 tcaacgcagg tttcgtccat tgtggatcaa acagccaagc tggtccaggg atatggaacc
    19981 agcccagaaa tgtgttgatc aatcctgcag atggagaaag cagctgcatc cataagatgt
    20041 agactgctac tcctgataag actgccggta aatagaaagc tgtacggaat acactgattc
    20101 ctttgatttt ttgattgagt actgtggcta aaaacacact gaaaatcgtc gtcagcggta
    20161 cattgaagat gacgaaataa acggtgttgt ataacgattt ccaaaataaa tcatcgtgaa
    20221 cgaacattct tttgaaattt gctagaccaa tgaaattcat cttggatgtc aaattataat
    20281 cggtgaaact accaataact gaaaaaagca taggccctag cataaatacc aagaacccga
    20341 taataaaagg cgagataaat aaataggccc atcttgcttc ttttttcttt cggatagata
    20401 aacgcttcaa attttcttgc ctcctctgta cctagacagt caaaaatgga ttattgattt
    20461 tgcttgacta agttttctac tgctttttgt gcatctgcca atccttcttt tggtgatttt
    20521 gttcctaaaa gaatctggtc aatctgttca ttcactaatg tcgtgtaatc cggagcatct
    20581 aaaggaactg gtgtgatcac cgtattttta aagttttcgt ccgccatttg atagatcatt
    20641 tttcctttat ccgttaggtt gtcattattc actaaattct cattggctgt cttgctcgcc
    20701 atgatatcaa aacttttttc gccgaatttt tcttgtactt ctggagaaga aagatatttg
    20761 atgaattcat aagaggcctc aggatctttt gctccgtatg gtacttccaa gacgaatccg
    20821 ccaccccacg accaatggcc tgaaccttct tctttttctg ggagctgcat cacgccaaaa
    20881 tcaaaatcat ccggtgcatt ttccatcaaa ctagagtaat aattgatatt ttgggcacgc
    20941 atggctacta atccggaaat aaatggatca gatacaccag acccaaattc ggcttctaat
    21001 ttattgatcg tatttttccc ataataatct tgccagtctt ggatccactc caaggcttcc
    21061 actttatttt tagtatcaat cttgactttt tcatctttgt caaaccaact agtcccgtta
    21121 tctgcgttta gcgcccatac atcagcccct aaattccata atggataaaa accgatgcgt
    21181 gtaaattctt ttccttcttt tttatctagt ttacgtgctg tttcttctaa ttcatcccaa
    21241 gttgtcggta gatcttgttc actgattcca gcttctttaa ataacttttt attataaaaa
    21301 atgacttgtg tatctgtatt gaatgggatc gcataaggat caccttcata ttctactgta
    21361 tcccaaagct gcggataaaa atccttagaa gtgtcttttt ctacatattt ggagagatta
    21421 gttgcttgct gtgcttctgc tctttgggca acggaattta tgtcctgtac aataacatcg
    21481 ggtgcatttc cagctgttat tgcagataaa gatttagtcc agatgtcacc ccatggctga
    21541 tacttataat ttacatggat ctcgttttgt gattgattga aatcctcaat gatttcttcg
    21601 atagcttctt ttcgtgcacc ggatccccaa aaggaccaga aatcaatatt ttttcttcca
    21661 tcacttgttt tttcagaaga atttgctgca cttgaactgg catcgcttgc attacttgat
    21721 ccgcatcctc ctaataaaaa caatgctgaa cttgccagca accctgtaaa caataatttt
    21781 ttcatatttt acctccaaat tttaatgtaa ccgatgccgg ttttaatata acgatatcat
    21841 tttgttctga aaataacaat ttataaggta tgattctaaa aaaattatta atgataccaa
    21901 tactttatat aattcgcgag cgctttcttt gaatttttta atctttcgta gcagaatgag
    21961 aatgtattaa aaatagatta ggaggaattt tgatgtttag acaccagaaa gaattgcagt
    22021 ttgaagcaaa accagatcgt ccgaatccat taatcgcgaa atatctgcag gagctgatcg
    22081 gcggccaata tggcgagatg agtgtagcta tgcagtacct gttccaaggc tggagctgcc
    22141 gaggagaaga aaaatataaa gatatgctga tggacattgc aacagaagaa atcggccacg
    22201 tggaaatgtt ggcgacaatg gttgctcgtt tattagaggg tgcgcctgtt gaagatcaag
    22261 aagcagcgat gcaaaaagat ccaacaatcg gtgccattat ctctggaatg aatccacagc
    22321 acgcgatcgt agatggctta ggacctcgtc ctgctgacag cgtgggcaat ccatggagcg
    22381 gtgcctatat cattgcgagt ggcaacttgt tagcagactt tagagctaat ttaaatgccg
    22441 aatcacaagg aagacttcaa gtagcacgta tttacgaaat gatcgatgat cgtggcgtaa
    22501 aagatatgct gtctgttctc cttgcaagag atagctatca tcaaaatcta tgggaatgtg
    22561 cagtgaaaga attagaagaa aaagaaggtt caatcttagt cccaagtact ttcccgcgtg
    22621 acaaagaacg aaaagacatt gcttatgact tctataactt ctcagaggga gaccaaagta
    22681 gtgaaggttc ttgggctagt ggcaaagcac tggatggcga aggcgaatat caatggttga
    22741 aagaacctaa gatcgaaggc gctgcaccaa aattagaacc agtaacacca aaaatgtatg
    22801 ggacacctcc attcaagaaa taaatatcta cccgtagaaa cacccgtttt ttgttccaca
    22861 cgctttgtga gcaaaactga ctaaagtcat taatcataac cacccttcaa aagggtggtt
    22921 ttctctagag ctataagctc aaatcaccgg ccagcgccta aagacgctgg ctttcatatt
    22981 ttatgttcaa gccatattgc ctttgccagt tttgcccacc tcttaaaagg tttatgtact
    23041 actccttagc ccttaaaagg atcgtcttac tctcgtacac tcagcttatc taacgcacta
    23101 tcatgttttt cttgttcttg aatgtacttt ttgatggtcg cttcattttg tcctactttt
    23161 gtcacatagt atccttccac ccaaaagtgt cgatacccaa atttatattt tagatttgca
    23221 caatctcttg atgatctcct gaatattggc tcgatattga ttataaatta tttttcttct
    23281 atactttggt gtgaatacaa tgtggtattt acacatctac tttgtacggg ctaaactatt
    23341 tccctttatt gctccacccg catagcaagt ggttttgtat ttcaatcgct cggcgcgctc
    23401 aattaggtct aaagacaata aatctaaaaa cccgctgctt cactgacaga aacaacgggt
    23461 tttcagaaaa aaatgaaatg aaaaagatct cttacggcaa tctattttat ttttttgatt
    23521 ttttataaat ggaaaatgct tcaagaagtc caagaaataa agccgtataa aaacaagaac
    23581 ctatgaaatc tttatttatt agatattcaa
//
LOCUS       DAZAOD010000035        23234 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000035 DAZAOD010000000
VERSION     DAZAOD010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.036"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(93..1244)
                     /gene="queG"
                     /locus_tag="ACHDPO_001398"
     CDS             complement(93..1244)
                     /gene="queG"
                     /locus_tag="ACHDPO_001398"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFN3369034.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(1263..2015)
                     /locus_tag="ACHDPO_001399"
     CDS             complement(1263..2015)
                     /locus_tag="ACHDPO_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369035.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(2156..3105)
                     /locus_tag="ACHDPO_001400"
                     /pseudo
     CDS             complement(2156..3105)
                     /locus_tag="ACHDPO_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
     gene            complement(3106..3945)
                     /locus_tag="ACHDPO_001401"
     CDS             complement(3106..3945)
                     /locus_tag="ACHDPO_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFN3369036.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(3942..4688)
                     /locus_tag="ACHDPO_001402"
     CDS             complement(3942..4688)
                     /locus_tag="ACHDPO_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFN3369037.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            4926..6296
                     /locus_tag="ACHDPO_001403"
     CDS             4926..6296
                     /locus_tag="ACHDPO_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFN3369038.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(6351..7247)
                     /locus_tag="ACHDPO_001404"
     CDS             complement(6351..7247)
                     /locus_tag="ACHDPO_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFN3369039.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(7361..7531)
                     /locus_tag="ACHDPO_001405"
     CDS             complement(7361..7531)
                     /locus_tag="ACHDPO_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369040.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(7528..8205)
                     /locus_tag="ACHDPO_001406"
     CDS             complement(7528..8205)
                     /locus_tag="ACHDPO_001406"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFN3369041.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(8296..9201)
                     /locus_tag="ACHDPO_001407"
     CDS             complement(8296..9201)
                     /locus_tag="ACHDPO_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFN3369042.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            9376..10800
                     /locus_tag="ACHDPO_001408"
     CDS             9376..10800
                     /locus_tag="ACHDPO_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFN3369043.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            10846..11877
                     /locus_tag="ACHDPO_001409"
     CDS             10846..11877
                     /locus_tag="ACHDPO_001409"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFN3369044.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            11884..13071
                     /locus_tag="ACHDPO_001410"
     CDS             11884..13071
                     /locus_tag="ACHDPO_001410"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFN3369045.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            13227..14609
                     /locus_tag="ACHDPO_001411"
     CDS             13227..14609
                     /locus_tag="ACHDPO_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFN3369046.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            14646..14966
                     /locus_tag="ACHDPO_001412"
     CDS             14646..14966
                     /locus_tag="ACHDPO_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369047.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(15166..15834)
                     /locus_tag="ACHDPO_001413"
     CDS             complement(15166..15834)
                     /locus_tag="ACHDPO_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFN3369048.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(16023..17449)
                     /locus_tag="ACHDPO_001414"
                     /pseudo
     CDS             complement(16023..17449)
                     /locus_tag="ACHDPO_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612187.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            17692..18147
                     /gene="tnpA"
                     /locus_tag="ACHDPO_001415"
     CDS             17692..18147
                     /gene="tnpA"
                     /locus_tag="ACHDPO_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFN3369049.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            18412..18510
                     /locus_tag="ACHDPO_001416"
                     /pseudo
     CDS             18412..18510
                     /locus_tag="ACHDPO_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(18733..18963)
                     /locus_tag="ACHDPO_001417"
     CDS             complement(18733..18963)
                     /locus_tag="ACHDPO_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFN3369050.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(19193..20011)
                     /locus_tag="ACHDPO_001418"
     CDS             complement(19193..20011)
                     /locus_tag="ACHDPO_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFN3369051.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            20172..20861
                     /locus_tag="ACHDPO_001419"
     CDS             20172..20861
                     /locus_tag="ACHDPO_001419"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFN3369052.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            20875..22377
                     /locus_tag="ACHDPO_001420"
     CDS             20875..22377
                     /locus_tag="ACHDPO_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFN3369053.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            22390..22866
                     /locus_tag="ACHDPO_001421"
     CDS             22390..22866
                     /locus_tag="ACHDPO_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFN3369054.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(22963..23073)
                     /locus_tag="ACHDPO_001422"
                     /pseudo
     CDS             complement(22963..23073)
                     /locus_tag="ACHDPO_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6940 a         4365 c         4299 g         7630 t
ORIGIN      
        1 aattctctta aaaaaatgta aaaaatacaa aaaaaccagt aattgttaca acaattactg
       61 gacaaaaact ttgaataatg ttaactattt ttttatttta actttctccg caataatttc
      121 tgggcatgtt ccaattcgtt tataacgact tcttctgttt ctttagctaa tatttcatct
      181 aatacatcaa gccatttttc cggttctttt gttcctagac gtccaatagc ccaagctgct
      241 gttcctctga tgacagggcg gacatctgtt aaacattctg aaatctcagg caatgccgtt
      301 cgatcaccta gattagctaa agcaatcaat gcgtttctct gcaaaggttt cttcccacgc
      361 catgaaccag ctaaatgccc aaattgctgt ttgaagtctt tattagacat cgaaagcatt
      421 ggctttaatt ttggatatat ttcgtctact tttggttcca tctcttcatg aaaatgaaaa
      481 tcttttcctt gattgtaagg gcagactaac tggcagatat cacatccata aatgacattt
      541 cgcatttttt tacgatattc ttccggcatc atcccttttg tctgagtttg ataagacaaa
      601 catcgctggg cattcattct tccgtcacca agcaatgctt ttgtcggaca agcagtcacg
      661 cagcgcatac agtcaccgca accaaattct cctggtttat caggctcaaa tacaatatta
      721 gtaacgatct caccaagata gacaaatgaa ccgaactctt cagtgatcaa caatccgttt
      781 cgtccaataa atcctaaacc agctcgctgt gctacagcga catcgatcag ttctccagta
      841 tctacttgcg gagctagacg ccattcctct tctttttgcc atttttctgc tcttgtttgg
      901 atgaattcga tcaatcggtt caaacggtct ctgagtatat catggtaatc gatcccccaa
      961 gaagcacgag caaactgccc gcgtttttca tccctaggca cttcttcatg gatcctagta
     1021 ggatacgcaa gtgcaatgga aatgatcgat ttcggctgat caaatgtcat ttctggataa
     1081 agacgctcat cgatatttgg atgttcaaag ccagaagtat ggccagctgc tttttgttct
     1141 tccaacgatt cttttaatga atcaaaaggt tccgccgtgg tgaacccgat tttgtcaatt
     1201 cctaatcgtt tgctttcttg tatgatttct tcttttaatg tcatggtctt cctcgcttgc
     1261 tgttaacggc tgtataaccc ataatatagt ttttcttttt tcagctggac aaactggatc
     1321 tgctgatcgg caatcttctt ttcttccatc catttttttc ttgcagcaaa tacttcccaa
     1381 taatttgttg aaattaattt tcttttgtta tctaatgcat taaaaaaatt caatgaaact
     1441 ggttttgtac ttaacagttc atggagcctt acctcttccc atggcgaaaa ctcagacaga
     1501 tcgcgggaat acaatacttc ttcatagaga tttttttgct gtgtgtacgt gaatgtttgc
     1561 gggattttcc caggcctagc aatttctact agacgattat aaaacatatt cattaatttg
     1621 ctgttggcaa taaattgact tttataatag gccgactgga tctttttgat tactccttct
     1681 gctttgatga ctgaaaataa tgcaggccat gctttgacgg ttatttcgtc gttttgttta
     1741 actaatacgc caggtgtgaa gccgactgga gaaaggaaca caaaataacc gataccggta
     1801 ttttcatcta aaggctgaaa ttcatcaaac aaccatttgc ctatgtacag ctcttcatct
     1861 ggttctgttg tctcattttg atttgctatg aataatttag ctaattctgc ttcaagaaat
     1921 tgaaggtctt gatccttgtc ggtattttcc tgctggctga tcaatcgaaa gacttcttct
     1981 ttaatcgtat atttatcttt acgtgtaaaa ttcatagcca caccttcctt ccttactcta
     2041 actataacgg aatttcttca aaaaaggtat ctgtacgacg aaaaacagca taattttttt
     2101 tcatatctct tataaaaaat gcaaggtctg ctcctcaagc tagaccttgc acttttcagc
     2161 tttcttttgt ttgtgacaaa ccttcatgga tcgtttcaat attccatttc atcatctgat
     2221 agtaagaatc tccttgttct ccttcttttg ctatggaatc agtgaacagt ttatcataga
     2281 ttttcaaacc cgtttctttt gctacccgtt ccatgcttct tgagtctaca ctggtttcca
     2341 cgaataaaac cggtacttct tttgctctta tctgatcaat gatcgctttc atttgatcag
     2401 gcgtaccttg actttctgta ttgatctccc atatataagc tgctggcaaa tcatatgctc
     2461 gtgaaaaata cttgaatgcc ccttcacttg ttactaataa ttttttgttc tcttcgatag
     2521 aagcaaaact ttccttcgct tgtgtatcta attcttttag tttttccaca tatgcttctg
     2581 cattttttta tagagtgtcg cattttctgc atctttttca gagaatatac gtgcgatttc
     2641 ctccacatat tttattccgt tagataggtc tagccaagca tggggatctg cttttgtatg
     2701 ttcttcaccg ctagttaaat aaagaggttc tacatttttg ctaactgcaa aataatcttt
     2761 tccttcttct tttttagccg tttccatcaa gttatcgaac cagctgttac ctgtttcaag
     2821 attcaaaccg ttgtataaaa taacatctgc atcgcttgcc tttttgatgt cttctggtag
     2881 tacttcatat tcatgcggat ctgttccgac tggtacgata ctgtggatat ctatttgatc
     2941 tgttccgacc tcttttgcca tgtccgccaa gatcgaattg gtagccacga ctgacaactt
     3001 ttctttactt ccttcatccg cttggtcaga agcctgcttt ccgcaaccgg ctaataccaa
     3061 gaaactaact gccaagatta aaaagagtga tttttttgtt ttcatctatc tgcttccttt
     3121 ctgaaataaa attccttttg ttggagaaaa taaaaaagca aggataaaaa atgcggtaca
     3181 tgctaacacg atcgtagctc ctgatggcca attgtaacta taactgaaaa acacaccgac
     3241 aactgcactt agcataccga ttcctgcagc tgtaatgatc attttcagta aatggttcgt
     3301 tagcaagtaa gccgtggcgg ctggtgtgat caacatggca atcaccaaga ttgttcctac
     3361 tgtctgtaaa ctgactacag ccactaatgt caaaaagaac atcaaaagat aatggatcag
     3421 cgatgtgttc agcccataag cttttgccat tgtcggatcg aatgatgtga tcttcaattc
     3481 tttataaaag aaaaagacaa atatcaagac gattccacta acgagtgctg tcagcaacaa
     3541 atcgctttcc ctaacagcta agacattccc aaataaaata tgatacaaat ctgtcgcact
     3601 ctgggcatat gaaatcaaga taatccctaa tgcaaaaaag gagctaaaga caattccaat
     3661 cgctgtatca tttttcaatc ggctccgctg agtcacgaaa ccaatcactg ctgctgttag
     3721 catcccaaaa gcagtggctc caaagatgta actaaaacca aacatataag aaatggctac
     3781 acctggaaga actgcgtgag agatagcgtc tcccatcaaa gacatccctc gtaaaataat
     3841 aaaagaaccg atgactccag aagcaagtcc tacaagcatg gaagtgacca aagcgtattg
     3901 caggaattga taattcatta atccatcaat aaaggattgg atcatttttt ctctcctcct
     3961 tttactaaat gtctgatgat ctcaccatag gccaattgaa ggttcttcga tgtaaagact
     4021 tcttgtactg gaccggaagc gatcagctgt ttatttaaaa gaataacctc atcgaaatat
     4081 tcttctactt tatgaagatc atgatggacg atcaaaatcg tttttcctga attcttcaat
     4141 tcctgcaaga tgtcaaagat ctttcgttca cttaacgcat caatccctac gaatggttca
     4201 tctaaaaaga tccattctgc tccttgggct agagctcttg caataaaaac tctctgaagc
     4261 tgtccacccg atagttcgct gatctgtctt ttggcatatt cttccatccc tacttttttc
     4321 aaagcttgtc ttgcacgttc tttttctttt ttcccaggtc tttgtccaat tcgtaaagat
     4381 ggatatgttc ctaaaagtac aacgcctaat acatcaattg gaaaggaaag atccaattca
     4441 cttcgctgtt ccacgtaggc tattttttta cggactgagt ttaccgactg tccagaaaag
     4501 gtgactttac cagtagtagc tggtatcaac tctagcaaag atttcataaa tgttgatttt
     4561 cctgcaccgt ttggtccgat aataccggta attttttgtg gatttatcgt caagttgata
     4621 gttttcaaaa cagttttccc ttgataagcg gctgaaaggt cttgaattac aatggccgta
     4681 cgttccaaat cttacactcc tttttaggtt tacctaactt tttatttaaa tatagtttaa
     4741 ctaaaatgga aagcattttc aagtagaatg atgaaaaagt ttttttcgaa ttttcctcgc
     4801 attttatgaa aattttctgt agaattacat caagagttca ataaggctaa cctaataatg
     4861 aaaaacatgt gttgaaacgt ttgattattt tttcttgttg actcaacaac gaaaggagtt
     4921 tttgtatgga agaagaaaag ttaactcgaa gtcttagtgc ccgtcatatc caaatgatcg
     4981 cactaggtgg aacgatcggt gtcggtctgt ttatgggtgc ctcctcaacc atacgttgga
     5041 cagggccctc agtgatggga gcctatgcga ttgcaggatt ctttttgtat ttgattatgc
     5101 gtgctttagg cgaaatgctt tacgttgatc cttcgactgg ttcttttgca aattacgcga
     5161 gcgagtacat ccatcctgtg gctggctact tgaccgcttg gagtaatatt tttcaatata
     5221 ttgtcgtagg aataagtgaa gtgattgctg taggatctta tatgaattat tggtggcctg
     5281 atttgccggc aattattccc ggaatcattg tcgtcttgtt tcttatgctg gcaaatctta
     5341 tttctgtcaa ggcgtttggc gaattagaat tttggttttc gatcatcaaa gtcataacga
     5401 tcattttgat gatcattgca ggtcttgggg taatcttatt tggatttggt aatcatggtc
     5461 aggcagtagg gatttcaaat ctttggaaaa atggtggatt cttcactgga ggcgtcaaag
     5521 gatttttctt tgcattatcg atcgttgttg cttcctatca aggaatcgaa ctgatcggaa
     5581 tgactgctgg tgaagcagag aatcctaaaa agacgatcat tgaagctgtc cagtccacta
     5641 tcggtcgaat cttgattttt tatattggtg ctatttttat cattgtgagt atctatccgt
     5701 ggaatcaatt gagtgagatt ggttcacctt ttgtacaaac tttttctaaa gtcggcatta
     5761 catttgctgc aggactgatt aattttgtcg tgattacagc ggcattatca ggttgcaatt
     5821 cagggatttt cagcgcaagt cgtatggtct atacacttgc cataaatgga aagatgtcta
     5881 aaaaatttct gaaactatct cgtcacggtg cgccttttta tcctgtcgta gcaatctcag
     5941 gtggaatctt aattggtctg atcttaaatt atcttctacc aatgttcatc aaccagtcag
     6001 aaaatatttt cgttttcgta tacagctcaa gtattttgcc tggtatggtt ccttgggtag
     6061 tgattttgat cagcgagatt cgcttcaaaa agaagcacgc agataaaatg catgatcatc
     6121 cttttaaaat gccactatct ccttatacga attatgtgac acttgctttt ttagctatcg
     6181 tattgatttt catgtttatc aatcctgaaa cgagaatctc attgattatt ggactcgttt
     6241 tcttgcttta catgacgatc cattactttg tacgcgaaaa aagaaccgga aaataaaaaa
     6301 agaacgaagc ttcaccttag tggaagcttc gttctttttt attgctttta tcaattcaat
     6361 tttagcgtct caccgggagt caggaaataa ttctccatgc tcatcccatt cagcgacaag
     6421 atcgtttcta ctggtacgcc agttcgttcg gctatttgat ttggaccttc tccttccaaa
     6481 actacggttg tcgcagcctg tgaagtcgcg ctgttggtat tagtttcaga ggaatctgtt
     6541 gtgtcttgtg ttgttcgagc ttgcatttca gaagcttcta ccgactctgc tgtctcagaa
     6601 tcagaagatg ttgtgtcttg tgtgcttgtt gactctgctt gaagagaggc gctagtctgc
     6661 aaataaatat cggaaatctt agcgacatga ttcgtataat tagccgataa ttgattgatc
     6721 aaagtatcta agtctacacc gtctttattt tctgctgcct gatacgctgc acgtaatttt
     6781 ctgatccctt cgtcggagat tgcttgaagc tcacgtgctt tttggttagc aactgctgat
     6841 aaaccagcta ttccctcttg atttccctga atttctgtct ggtattcttc aatcaatgca
     6901 ggcgtctttt cttcgatctt tttcgaataa tcatttacga ttgcttgaag ttgctctggc
     6961 aaaccatttg ctgttttttc ttcagaagtt tgtgtctctt ttgttttagt tgatgactca
     7021 cttgtttgtt tcgtctctgt tttctttgtc gttgtttccg ttatggtcgt acttttcgct
     7081 tctgacgaat tttttccatg aaaatataga cccgcaactc ctcctgctat gatcaaaaac
     7141 acggcaactg ctgccccaat catgatcatc cgcttacgag ctgcctgttt ttgctgtctt
     7201 cttcgggtca tccgaacatt ttctccccac tcattttcat catacatttt tttcaccacc
     7261 aatttttatg tataatagcg ttatcaaacg cttcatattc ttattgtagc aaataattgt
     7321 cgctgtgcac atttttatct ttgttattta taagaaaatt tcaccagttg agatgattcc
     7381 aagattgtcc gtcgatttct ccttgcagct gcattgttcg ttcgtctatc tcagccatca
     7441 gtttctttat ttcatataag agcgcacggt cttgatattc tgatttttcg cttaattcat
     7501 ctaattgttg gatcagccaa tcatttgtca taatgaagtt cctttcattt cttgcagtgt
     7561 aaaggtcaag tcttcgatct gctcttttgc ctcagtcagt gcttctacga tatatgcttg
     7621 tttttcagat tcttcttcct gcattttctg attttcctgt actctttgaa taaaccagtc
     7681 aatccgctga gtcagcgatg gtttgccttc caatgagaga tactgctgat aagcaattag
     7741 cttctcccaa cgtttttcct gggataaata cataaattgt gctaaaacga atggcggaag
     7801 ataggtcata tggaatttat ttgcgattcg ctgatacggc ctcaaaaatt cggaaatcgt
     7861 atattcttct tttcctccag cttggtattc tttttccgcc acacctgttg tcaatacgat
     7921 tcctagttct ttccctttta atacatgtgc tgctcgttcc aagacattat cttgccaaat
     7981 ttttaaatga gcaggagaac tataccagta aaacggaaac tggaaaatga tccgatcatg
     8041 ctgggccaag agctgtagtt cagtctctat atctattttt ccgtctggat aacttgattc
     8101 caaatgatgc caagtagctg gtaaaccagc agaagcttct ttgaaaaatt gctgatttaa
     8161 agattcttcg atcgttggat ggctaatgat gataagtgta cgcatccctt ttcctccttt
     8221 ttagtcttcg ctttacagtg tagcataacc gccacaagtt tcttttgccg atgcttgtca
     8281 ttttaaccag actaatcagg ttgtccaaga aactgcggtt tgtttttcca actgtttttt
     8341 caaggtatcc aaagcaatat tcttaaaatt ttcgtttttc atacgtttac gatagttcgt
     8401 agccgtttct ccggtactct ttttgaacat tcggctaaat acgactagac tattgaaccc
     8461 tacttgatag gcaatacttt ccacggattc atccgtcaga gaaagaagaa acgcccctcg
     8521 attgatccgt accccgatca aatattcctt gatactggta cccatatgat ttttgaatac
     8581 tcgcgacaaa tggctccgat tgaccgctaa atgctgggcg atttcctcaa cagacaattt
     8641 ttcagcataa tgtgcctcga tgtatttgac tgtttcaaca gctaaagagg aatgaacctt
     8701 ttgtacacca ccgctgacct ttccgccatc ttttaaaagg actgataaaa aacggtaggt
     8761 taatgctgtt aactgtaatt cattttccaa ggtttcttcc gtatctttca tgcattctaa
     8821 aataatgtcg atatattttt gtatgtcaga agagaccatc gtgtattggt cttctctgaa
     8881 aagcgactgc cgaatgattt cttctgcagc actcccacca aatgaaagcc agcaatacat
     8941 ccacggatct tctccatctg ataagtaaaa cgtcgagtct cctggacgaa tcaagaacag
     9001 atcacctttt ttcaattgga attgttgatt tttcacatga taagatcctt tgccttccat
     9061 cacgacatgc aggatgtaat cattgcgaat agcaggacca aaagaatgaa acggcatcgt
     9121 tttagagaaa ccacaaaaat caaaatacaa ttctttttct acttgttgat gttccttttt
     9181 taaaaaaatc gattgctcca cgtctatccc tccttactcc tttagtataa tgcaacaaaa
     9241 agttaaataa aagtcacaga aatatattaa aaaggaagcg atttcttgtt aagtttaagt
     9301 cattaaaaga tctttgttat tcgttgtaac cggtttactt agtattatat attgaacagg
     9361 agaggaatac agattatgaa aagcaaaatg atccaacgtg tgtcctacgc tttaggcgct
     9421 tttggacacg acacattcta tgttacatta agcacttatt ttatggtatt cgtgacaagc
     9481 cagatgttcg caggaacaga taaggcaacg aatgcaaaaa tgattgctac agttacaagc
     9541 ttagttgtag gtatccgctt agttgaaatt atttttgatc ctttgattgg tggcatcatc
     9601 gataatactc gtacaaaata cggtaaattc aaaccatggt tagttatcgg cggcgttgtt
     9661 agttccgtac tcttggtagc aatctttacc aatttctttg gcttagctac tcataatacg
     9721 actttattta tcatattatt tgcaatcgtt ttcatcttat tggatagttt ttattcattt
     9781 aaggatatcg ctttttggtc aatgattcca gctttgagta cggaaacaaa ggaacgtgaa
     9841 aaatttgcta cgtttgctcg tttcggctct tctctaggtg caaatggtac tactctagtc
     9901 gttgtcccta tcgttacttt ctttacctat cttgttactc ataaacatat tgaaggcgct
     9961 tcaggctggt tctggttcgg tgtgattgct gctgttattt caggcggtac tgcgattatc
    10021 actgccttgg gcacaaaaga agtcgatact gcgatccgtc agcaaaatga aaaagctggg
    10081 atcaaagatg tgttcaaagc agttgctcaa aatgatcagt tgatgtggct tgcccttgct
    10141 tatatcgctt atgcgattgc caatgcagca acaactgccg tattattcta cttcttcaaa
    10201 tatgtacttg gccaaccaac tgaattttgg atcgttggtc tagttgctgc cttacttggt
    10261 ttagtagctg ttccactatt cccaatgctt acacgcgtca tctctcgtcg ctacgtttac
    10321 cttggaggga tcgcaatgat gatttcttct tactttttct ttacgatcgc aggttcaagt
    10381 ttgccaatcg ttatcatcgg gctagtattg ttctacttcc ctcaacaatt gattttctta
    10441 tccgctttga tgacgatcac agactctgtt gaatatggtc aatggaaaaa tggtatccgt
    10501 aacgaagctg ttactctatc aattcgccct ttactagata aaatcgctgg tgctttgtct
    10561 aacgggatcg tagggtttgt cgctatcgct tctgggatga ctggtaatgc tactgctgct
    10621 gatatcactg ctcatggcgt aacgactttc aaagcttatg cattctatgc tcctgctgct
    10681 ttgatgattt tctccgctat tatttttgct tggaagatta cattgacaga gaaaaaacat
    10741 gcacaaatcg ttgagaaatt ggaaaacaaa ttggctccag ctgatacaat ggaagattaa
    10801 cttcacgatg cagtagttcc ttcccattaa gaaaggatct tgaaaatgaa gattacagaa
    10861 aaagattttg gccaaggtta tcacttgata accttggaga acaaaaacaa gctagcactt
    10921 tctatctctg atttaggtgc tagaatcgtc agtttaaaat caaatgatcg agaattagtt
    10981 ttgggatttg acaccgctga agaatatatc gaaaaagatc cgtatatcgg tgcttctatc
    11041 ggtcgcaccg cagggagaat cgaaaatggc cgcttttctc tcaatggaaa aacttaccaa
    11101 ttagccacag atccaaaaac tggacataat ctgcatggtg gtgctcctgg atttgaatta
    11161 aaaaaatggt cttatgtcat tttgaatggc gaaaatgaag cttctgtcat ttttactact
    11221 acaagtcccg acggagaaca tggttttcca ggtacaatgg atgtggaaat ccgctatact
    11281 ttgacaaaag ataatatctg gcgagtgacc tctcgcggca ccagtgacca agatacttta
    11341 ttcaatccga caaatcatgt ttacttcaac ttgacgggag atgcttctca gtcaatcgat
    11401 caacatgagc tttggctcaa tagcgaagct tatgctcctt tgcgaacaga tagtattcct
    11461 ataggggtaa aagaaaatgc tgcaggaagt gctttcgatt ttcaaatacc taaaaaatta
    11521 gcgtccgttt ttgctagtga tttggatcaa aaaaatcttg ttgacggaat cgatcatcca
    11581 tttttcttaa aagaaaccgg cttgggtaaa gaagccgctc gcttgactag ccccgataaa
    11641 agaatccaag tagatattgc tacagatgct tctagtgtgg ttattttcac tgcaaatttc
    11701 ggcacagaaa caccagaaat gcgcaaccga aaactggcac atcacggtgg catcacattt
    11761 gagactcaaa cagctccagg tgcagagcgc ttctcagcat ttggttcgat tcatttaaaa
    11821 gccggatcag tatttgaaac agtaacagaa ttcaaaatca aaacaagaaa ggaataactc
    11881 atcatggaaa tcaaaagaag cttaaacaca aaatttgccg aaacattcgg acctaaaaaa
    11941 actacacaat acttctcacc aggacgcatc aatttgattg gtgaacacac agattacaat
    12001 ggaggccatg tcttccccgc ttccatcact tatggaacgc aaggtgtagc agcacctcga
    12061 gacgataata aaatattagt ttattccaca aactttgacg atatcggtgt cattagtttt
    12121 actttagatg agctagaata tgataaaaaa gcaaactggg caaattacgt aaaaggaatg
    12181 gtccttaaat taaaagaagc tggacactca atcgatcatg ggtttgagtt attagtggaa
    12241 ggaacaatcc ctaatggtgc aggactttcc agtagcgctt cattagaatt attagtaggt
    12301 gttgtattag aagatctgtt tgatttaaaa acagatcgct tggaactagt ccaaacaggt
    12361 aaaaaagtag aaaatgaatt catcggtgtc aattcaggta tcatggatca gtttgccatc
    12421 ggcttcggtg agctagatca tgcaatctta ttagatacaa atacgctgaa atacgaaatg
    12481 gttccagtga aactagatgg ttatgcaatc gtcatcatga atacgaataa gcggcgggaa
    12541 ttggcagatt caaaatacaa tgaacgccgt agcgaatgcg aagaagcctt ggcacgtttg
    12601 caaaaaactt tgcctatctc ttctttagga gacttagatg aagaagaatt tgaatcaact
    12661 attgaccaaa tcggcgatga tacattgata cgcagagctc gccatgccgt ttctgaaaat
    12721 cagcggactt tgaaggcaaa agctgaatta gaagctggga acttagaagc atttggtcaa
    12781 ctgttaaatg attctcacca ctctcttcgc tatgattatg aagtaactgg gatcgaatta
    12841 gatacactag tagatgctgc tcaaaaacaa gaaggtgtct taggtgcacg aatgacagga
    12901 gctggatttg gtggctgtgc gattgctctt gtcaaagaag aaaatatacc tgccttcaaa
    12961 aacaatgtct atgatgaata catgaaagtt gtcggctatg ctccggaatt ttatgttgca
    13021 cacattggaa atgggacaac aaagatcgat ccagaagctg ttcatgtttg ataaaaaaat
    13081 caacgatctc agctaaaaac aaatagataa aaataacctc tcagcaattt ccaaatgtga
    13141 gccttttgct cgtatttgaa aattgctgtt ttttattgac acggaaagag aacgtgtgtt
    13201 ctaattgtgt tgaagaggtg attgttatgt gggcgaatca aaatccggta tttgtttatg
    13261 aaaaagaacc ttcaagagat attttatgta ttgactgcaa atctttttac gcctccgtag
    13321 agtgcgttga aaaggatctt gatcccctta caactaaatt agtagtcatg tcctatccgt
    13381 ccgattcgac agaaacacgg ggtagcggat taatcttggc ttccagtcct gcagcaaaaa
    13441 aagcttacgg catcaccaat atcagccgtg ccagagatct tcccttcccc tatccaagtg
    13501 atttatatat tgttgcccca aggatggcct attatatgga aaagaacaga gaaatcaatt
    13561 ctatctataa aaaatatgca gacgaagcga accatcatgt ctattccgtc gatgaaagct
    13621 tccttgatgt aacaaatagc atggcactct ttggtaaaac aaatgcgtac gacatggcta
    13681 aactgatcca taaagatgtg tttgagcaga ccggaatcta cacgactata ggaattggcg
    13741 ataacccgct acttgctaaa ctagccttag acaatggctc aaaagacgga aagcaaatgt
    13801 ttgctgaatg gcgttatgaa gatgtaccag aaaagttatg gaaaatctca gatatcactg
    13861 acttttgggg aatcggcaaa cgaacagcaa aacgtctgaa acaaatgggt atacattctg
    13921 tttatgattt agctcacgcg gattattatc acttgaaaag caagctaggg gtcatcggta
    13981 ctcagcttta tgcccatgct tggggcatcg atcgaagttt tttgggacaa gaatatacac
    14041 caaaatcaaa aagtatcgga aatagtcaaa tcctagatag agattataca agacgagaag
    14101 aaatcgagat cgttatcaaa gaaatggccg accaagtcgg cactcgcttg agacgatctg
    14161 cagcaaaaac acaagtagtc agcttatggg taggatactc tttaggctat cttgatccaa
    14221 atggcaagac cgggtttcac cagcaaatga aaatcgaagc gacaaatgct agcagagatc
    14281 ttgcagatgc tttattgacc attttccacc agcattacca ctaccaggat attcggcgtg
    14341 taggcgtgaa ctgttccgac ctcgtatacg cgacaggttt acagcttaac ctttttgaag
    14401 atcctgaaaa gcagataaat gaagcgaaag ttgattttgt tgtcgatacg attagaaaaa
    14461 aatacggctt tcaatcaatc atccatgcgc atagtctctt gcaaggagga cgcgccatcg
    14521 cacgtagttc tctcgttggc gggcatgcag gtggtatgag tggattagaa ggtggaaaag
    14581 atgagacgga cagcaaaaaa attcattgac tataacgagt atcgagatcg gccatttgga
    14641 ttaaaatggg ggactgcttt tgcgatggaa gaactagtca acggtatcaa aaaaatgaag
    14701 aagaagcacg caaacagcct cttcctaaac aacaaatgac attgcaagaa atcgatagta
    14761 tactgacaga agccttttta tctcgtaaag cagtaatcat tcagctcaat ttaaaagatg
    14821 aatttggaag actcttggat gaggtcgaag ggcacttcat tggtgaagcc tatgaagatt
    14881 actttatgat tgaccatcag ccgatattgt gggaagacgt acggtatatt gagttaaagg
    14941 aaacaaaaaa atggtttgtg acatgagagg ttgtgacaga agtgatcaac ttcaaaaaat
    15001 aagaaaggat ttttcgaaaa ttgcttctta aatttttgtg gaattttggc ttatttttcg
    15061 aagaagcaac ttctggaaca acgtatatta gatatcagag gttgtgaaaa agtcgcttag
    15121 ttttgagtaa caagccaagg cgctgatttc acaacctctg tctatctatc catctattcg
    15181 gtaagattca tgcatgacgt cttctttatt tagtatgtag agcccttttt cttctgacca
    15241 ttcaacataa atcagctgtt ttacatctgc atagccttct ttcttcaagt tctccataag
    15301 ccatgcttca gtcaattgat tggactgaag cactttatgc tgaatttgcc cttcatctac
    15361 aagcaggatc gataaagctt tgtcttcatc tgattttttc aatacactca tttgaccggc
    15421 attctctagg ataacatgtt tggcattttc aagaaaaaag cattcttgct gtcttaagat
    15481 tgctcgcaac tgctccatct cgatatggtt atttgtcaac tctgtcatgt tgatgacgcc
    15541 gtctttgatt agaacagatg gctcgccttt gacccaacga ttgacctttt catttttttg
    15601 gacgatacgt tcgataccat aaatcattac tgcccaaagc gcaatggcaa ataggacatg
    15661 ccctacatgg acattgtcat cataggttga ttcttctaag atcccaccta aaacaagcgt
    15721 atagactaaa tcaaacggtg tgatttctga catggatttc ttcccaagca aacgtaccac
    15781 taataataaa ccgatcaacc cgaacaccag tttcattgta attgaaaaaa tcattttttc
    15841 tccccctaac tatctgttaa ttaaattata tatgctttct cacgaacacg catggaatat
    15901 acaaggaaga aatgtatcct tttactaaaa aaaggactgt gacactgtag tgacccccaa
    15961 aagttagact tttttggagt ggagaaatcc actccttttt tttatgctct aaaatgatat
    16021 ttttacacaa ccgttacggt tgttttacga aattggacga gactttgcca gtttaatttc
    16081 tgttttatcc gttcattatt gtagtaatag atatagctat cgatggctga ttttaattcc
    16141 tcgaaacagt tataaacttt cccgtgaaaa atctcttgtt ttaataagcc aaaaaaattc
    16201 tccataagtg aattatctaa gcagttccct ttccgagaca tgctttgaaa gattttgtac
    16261 tccttcaatt tgtttctata agctttcatt tgatacgccc aaccttgatc tgagtgaaac
    16321 gtacgacgat agggacaatc gttagtggtc tggatagctt cctccaaacc ttccattacc
    16381 gctaatgcat tgggcttttc agagatacga taggataaaa tctcactatt gaacatatcc
    16441 ataaaaggat ctagatacaa tttcttttga cggataatgc ctttggcatc cacttcatgg
    16501 tatttaaatt cagttgtatc cgtcgtgatt ttctgatggc agatactggt gtagaaacga
    16561 cgatggatcc gatttttggc tactgctccg acttgtcctc gataagaatt gtagcgccgt
    16621 gatttacgtg tgtatgtcgt tacttttatt cctagcttct tgatcaggcg ctgaactttc
    16681 tttttattga tagagaaacc gcggtttctt agttcattgg tcatccgtaa acagccataa
    16741 tccttgtgct tctcccgaac tttaagcatt tccgcttcaa tctcttgatc tggattttta
    16801 cggtccaatc gtttttgcca gtacataaag attgccttag ggaactttaa agtttctaga
    16861 agctcaacta atttaaacgg tcctcggagg cttgcgatga ttcgtgcgat tgcttcattc
    16921 gtcgttgttg ggcttcctgt tttcgcagct tcctcaattc ttttaaaaag gcattttcaa
    16981 tttgaaggga acggactcgt ttctccaact cctcgatgcg ttcacgttct ttagacgttg
    17041 ctttagttgt agattttttc ttatttttgg gttcattttt cttagacaag ataggtggac
    17101 atcctttcgt ttttgagagt ccatcgatcc caccctcacg gaattgacgc atccaactag
    17161 cgatcaaatt agggttgttc atgttaagtg tgttggcaac ttcacgatag gacagctcac
    17221 ttgttagata taactctatc gcatccagct taaattgaac agaatatttt ttcttttgtc
    17281 gctttcttac tagaccctct tcaccaaatt cttgataggc attgatccag cgcttcactt
    17341 gtgatggagc cttaatggaa tatttctttg ccagataatc acttccgcct ttaccatcca
    17401 agtaatcatg aacgatcttt aatttaagtt caaaagtata cttagccata aaaaataccg
    17461 acctccaaaa gttagatttt ttggtctaac ttttgggggt cggtacaaaa cttaaaagtt
    17521 ttagaccctt ttattttctt aatgacttca gtcagttttg tgcgtaaagc gtgcgaaaca
    17581 agaaaaccgc gcgtttctac gcgtggaaga agtatcttta gcgataaaaa ctcctttcga
    17641 tatactagtg agtggctacc aaccgctcat cagatcgaaa ggagtttttt catgtcaaat
    17701 gacgataaaa gtttagcata tactcgttgg aattgtaagt atcatattat ttttacacca
    17761 aaatatcaac gaaaagtaat ctatgggcaa ttacgaaaag atcttggaaa aatacttagg
    17821 aagttgtgcg aaatgaaaga tgtggaaatc atagaagcac atgcaatgct agatcatatt
    17881 cacatgcttg ttcgagtacc accaaaaata tgtatatcca gttttatggg gtatctgaaa
    17941 ggtcgtagtg cggtactaat ccacgagcag cacgcaaatc tcaaatataa atacggaaac
    18001 aaatcctttt ggtcgaagag atactatgtg agtacagtcg gattgaatca aaagacaaat
    18061 gaaaaataca tccgtgaaca agaagctgat gatcgcattc gatatattat aagtaaaaga
    18121 gagtacgtag aaccatttaa aaaataaaga gaagtaagtg agtgaagatg agcagttggc
    18181 ggtcttttaa aaatcccctt ttaaggggca gcgagtgtcg accccttcta gggggattaa
    18241 aaatacaccc gtcctcacgg gtgtatgggt tactgataga cttgatttta actggtgtca
    18301 gaaacttatg tccagaaagg gtgatgaaat tttggcaatt tacggctatt caagaattag
    18361 cacaagcaac caagattaca aaacacaaat tcaaacatta gaaaatgctg gcgcagaaat
    18421 aatcttccta gaaaatcact ggattatcga acacctttgg aagtattttt gagttacgta
    18481 agtattgatg atctgtctaa cttaatttga caattaagag tatatttact tcagatggta
    18541 aggcaacaaa ataaaataca ataggcagat gaactaataa ataaaatctg tattaaatac
    18601 agataaatta atataaaaat caaaaggatc ataaactttt aacaagtgat gaaatgggtg
    18661 gaaattgatt cttatagaca gtttgtctca taacattgaa gtattttgca attttagcat
    18721 tgaaacactt ttttaatctt caacgttgtt cttataaaca agatgattgg gaatcttttg
    18781 aattaacact gtatagctta gaacaccctt tatagaaaac attcgcttag caatcttaat
    18841 aattccttgt gcccgatgtc gtttagattc agtaggttcc tgctcatcga tcatggaaaa
    18901 aatttgaagg atcagatcct taataaattt atttaagaga ggatgatcca ttgcttcatc
    18961 catactcgat aaactagtga taatgagcta cacgtttttc tttcaagttg atcaatagct
    19021 tccacgataa aaatatcttt agataaaatc aagaaccgta ggaactacag ggatatttgg
    19081 tcaataagag ccaccgctat tagtaaaaaa taagctatca agtatgctct catcccaaga
    19141 attgcctact tcaatcgtta aaaaccgtta ggtttagcta agtgggggta gttcactcaa
    19201 tacttttatc aataatagag cgcaaaactt tttctcttaa ttcaactgaa tcaatattat
    19261 tgttttgttc ataaccatga actaatagat cacaaatata aagttgtgat atttttccag
    19321 ctaaagatcc accattaaga aattcttcaa tggctgtttg taaaactaag tctgcagact
    19381 ttcctatagg tgaatgaata tagttagtta tagcaataat ttttgcgcca ttttttttag
    19441 ctattttcaa tgaatcataa gtatctttcg ttttcccaga taaagaaaaa atgattacta
    19501 aatcattaac tgttaataaa gaagcgactt gggcttgaaa atgagggtct agtacagctt
    19561 ttgcttgaac tcctacgcga agaaacatat tttctaaatc aagactagta tttccactag
    19621 atcccactcc aaatatatat atgttttttg attgagtgat cattttaatg gcttcattca
    19681 atttttcttc gtctaaaagc ctaatagtgg aatagagagc ttctgttaaa ctattagcaa
    19741 tttcatcata gtactttaca ctagtcggat gttctttttt ttgactaaag tcttcctttg
    19801 caatttcaat ttttaaatca gaaaaaccag aaaaaccaat tttttgacaa aagcgaataa
    19861 tagtagcatc gccaactttt gtgtttttct taatatcact catcgtacta taaataatag
    19921 ttttcccaga atttaaaata aaatcagcga cttttttttc agacttcgtt aaaaatggat
    19981 aattttcttt aattaaatag atataactca tacaaactcc tctacaattt caacttttct
    20041 ccattatact ccaaaataat aaaaaaaact cctaaatact ccatttttat ctttactttt
    20101 atgaaagcgg atgctatatt gtttttggag ttgttatcca aaaataataa aaaattggag
    20161 tgtttaggat aatggataaa aagaggtttt tagatcttat ttcaaaaggt ttgattgttt
    20221 cctgtcaagc attacctggt gaaccatttt acaaagagga agaaagttta atgccttatt
    20281 ttgctttggc tgctcaaagg gctggagcag ttggtatacg tgcaaattct gttcgagata
    20341 ttattgaaat tagaaagtgt gtatcattac caatgattgg aattattaaa agagattatc
    20401 caccagaatc tccattcatt actgccacta tgagagaagt agatgaatta gtagaaaccg
    20461 gtgttgaggt aatcgctctt gattgcactc ttagaaatcg acatgatgga ctatctataa
    20521 attcttttat tactaaaata aaagaaaaat atcctcatca gttatttatg gcagatattt
    20581 ctacatttga agaaggcaaa aatgcatata aagcaggaat agattttgta ggaactactt
    20641 taagtggata tactgaggaa agtaaaaaac aagatgggcc agatatagat ttgattaaaa
    20701 aattggtaga agaagggatt tgtgtaattg ctgagggaag gattcatact ccagaacaag
    20761 caaaagagat aaaaaaaata ggagttgcag gtattgttgt gggtggtgct attactcgac
    20821 cacaggaaat tgcatcaaga tttgttaaag cattaagtta gggggagaaa taaaatgttt
    20881 aaaaaatttt cacaattagg acgcgctttc atgttaccaa ttgctatatt accagtagcc
    20941 ggattactat tgggactggg aggagcgtta acaaatgaga gtgctataaa tgcttatcca
    21001 tttttagatc aaccgtggtt gcatacaatt ttaagtatta tgagttatgc tggaaatgca
    21061 gtttttgcaa acctagcact aatttttgca attggtattg ctgtaggact tgcaaatgga
    21121 gataaaggaa cagctggttt agctggtgga gtagcttatc tagtatatac tgcaactatt
    21181 agtgggtttc ttgaactttt ttcagcaaaa gatgcaacac tagatacagg tgtagtggga
    21241 tcaattgttg ttggtggtac tgttgcattt ttacacaatc gttatagaaa aattgaatta
    21301 ccacaattct taggtttttt tggaggatca agatttattc cgattgtttc tagtttagct
    21361 gcaatcatta ttggttcttt cttttattta atttggccac caattcaaaa tggtttagta
    21421 gttgctggtg aacaaattgc ccaaatgggt agtttaggaa cttttttata tggtttttta
    21481 ttgcgtttaa caggtgctgt tggactacac cacaccattt accctttgtt ctggtataca
    21541 tctttaggtg gtaccgaaac tgtagctgga tcaacaattg ctggagccca aaatattttc
    21601 tttgcccaac tagctgatcc aaaccacact ggtctgttta cttatggtac tagatttttt
    21661 gcaggaagat ttgcaacaat gatgtttgga ttaccagcag catgttatgc aatgtatcgt
    21721 gcaattccta agaaaaatcg taaaaagaat ggtgggcttt attttagcgg ggcccttaca
    21781 tcatttttaa ctggaattac tgaaccagtt gaatatatgt ttttatttgt tgctccttgg
    21841 ctttatgtga ttcatgcatt cttagatgga ttatcttttt attttgctga tatcttaaat
    21901 attcgtgtag ggaattcctt ttcaggtggt ttgatcgact ttttattatt cggtgtactt
    21961 caagggaatg acaaaactaa ttggttaaaa ttaattcctt ttggtattgc atgggcattt
    22021 atatatttct ttgtttttac attctttatc aaaaaattta aggtagctat tcctggaatg
    22081 gaagaagaat cagaagttca ttctgaaaaa gtaataaaca aaaatacatc attacatgaa
    22141 gagtctctta tcattattga agctcttggt ggaaaagaaa atattgagtc tgttgaagct
    22201 tgtgcaactc gtttgcgtgt tgctgttacg aatggggaga ttattcaaaa acaaacaata
    22261 aaagacactg gtgcaactgc tgtcttcgaa gtgaagggtg gcatccaagc tgtttttgga
    22321 gggaaagctg acttattaag tcaagaaatc aatcaaatat taggaaaaga taattaggag
    22381 gtttttaata tgtttgaaat tttcaaaaag aaaaaacaag aaacttttta tgcaccttgt
    22441 tccggaaaaa tcatttccat cacagaagta aatgatcctg tcttttcaca aaaattacta
    22501 ggtgatggtt ttgccgtcat acctgatggt tcaaaaattt atgctccatt ggctggtcga
    22561 gtaacaaata tatttcctac taaacatgct attaatataa aaagcaactc aggcattgat
    22621 tatttgattc atattggaat tgatacagtt gaattacaag gagagccttt ttcgatttgt
    22681 gttcaagaaa atgatgaggt tactcctgaa acctcgttgg ttgatgtgga ttttgacaaa
    22741 ataataaaat ctggtaaaga tacttctgtt atagttgttt ttccggagaa aaatcagttc
    22801 aatgatttaa taatagataa tggtcgaatt gctcatggga attcatgtgg aaaaatcact
    22861 ttttaaaaaa gtgtatataa aaagctataa aataagctaa ataggatatt tgtcaaatga
    22921 agttggtgaa cagaaagaac tgttttcttt ctgttcattt ttttatttta ttagtaatga
    22981 ttccccatgc caaatcatga tccgtaattt aaagttataa aagcttcgaa atccattggc
    23041 atttcgttgg aataccttga tatgattatt caaatataaa atatagagag aagagagaga
    23101 gggaagatat ttataaaggg caaagttatg tttactcaac ttaggaaata gaaatagatc
    23161 aatttatatt ctcttgtcaa tcgaatatga accttagcac tatataccaa atatagtaaa
    23221 atgctgaaag atgt
//
LOCUS       DAZAOD010000036        23027 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000036 DAZAOD010000000
VERSION     DAZAOD010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.037"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            165..647
                     /locus_tag="ACHDPO_001423"
     CDS             165..647
                     /locus_tag="ACHDPO_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369055.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            844..1734
                     /locus_tag="ACHDPO_001424"
     CDS             844..1734
                     /locus_tag="ACHDPO_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFN3369056.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            2060..4534
                     /locus_tag="ACHDPO_001425"
     CDS             2060..4534
                     /locus_tag="ACHDPO_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFN3369057.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(4637..6373)
                     /locus_tag="ACHDPO_001426"
     CDS             complement(4637..6373)
                     /locus_tag="ACHDPO_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3369058.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(6370..7074)
                     /locus_tag="ACHDPO_001427"
     CDS             complement(6370..7074)
                     /locus_tag="ACHDPO_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFN3369059.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7205..7708
                     /locus_tag="ACHDPO_001428"
     CDS             7205..7708
                     /locus_tag="ACHDPO_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFN3369060.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            7668..8006
                     /locus_tag="ACHDPO_001429"
     CDS             7668..8006
                     /locus_tag="ACHDPO_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFN3369061.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            8027..9445
                     /gene="ffh"
                     /locus_tag="ACHDPO_001430"
     CDS             8027..9445
                     /gene="ffh"
                     /locus_tag="ACHDPO_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFN3369062.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            9557..10135
                     /locus_tag="ACHDPO_001431"
     CDS             9557..10135
                     /locus_tag="ACHDPO_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFN3369063.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10139..10660
                     /locus_tag="ACHDPO_001432"
     CDS             10139..10660
                     /locus_tag="ACHDPO_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFN3369064.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(10739..11293)
                     /locus_tag="ACHDPO_001433"
     CDS             complement(10739..11293)
                     /locus_tag="ACHDPO_001433"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFN3369065.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            11546..11821
                     /gene="rpsP"
                     /locus_tag="ACHDPO_001434"
     CDS             11546..11821
                     /gene="rpsP"
                     /locus_tag="ACHDPO_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFN3369066.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            11833..12084
                     /locus_tag="ACHDPO_001435"
     CDS             11833..12084
                     /locus_tag="ACHDPO_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFN3369067.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12208..12999
                     /locus_tag="ACHDPO_001436"
     CDS             12208..12999
                     /locus_tag="ACHDPO_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369068.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13169..13690
                     /gene="rimM"
                     /locus_tag="ACHDPO_001437"
     CDS             13169..13690
                     /gene="rimM"
                     /locus_tag="ACHDPO_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFN3369069.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            13680..14441
                     /gene="trmD"
                     /locus_tag="ACHDPO_001438"
     CDS             13680..14441
                     /gene="trmD"
                     /locus_tag="ACHDPO_001438"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFN3369070.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            14577..14924
                     /gene="rplS"
                     /locus_tag="ACHDPO_001439"
     CDS             14577..14924
                     /gene="rplS"
                     /locus_tag="ACHDPO_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFN3369071.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            15234..15476
                     /locus_tag="ACHDPO_001440"
     CDS             15234..15476
                     /locus_tag="ACHDPO_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFN3369072.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(15564..15710)
                     /locus_tag="ACHDPO_001441"
                     /pseudo
     CDS             complement(15564..15710)
                     /locus_tag="ACHDPO_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            15767..16081
                     /locus_tag="ACHDPO_001442"
                     /pseudo
     CDS             15767..16081
                     /locus_tag="ACHDPO_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
     gene            16110..17369
                     /locus_tag="ACHDPO_001443"
     CDS             16110..17369
                     /locus_tag="ACHDPO_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369073.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            17422..18318
                     /locus_tag="ACHDPO_001444"
     CDS             17422..18318
                     /locus_tag="ACHDPO_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369074.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            18329..19198
                     /locus_tag="ACHDPO_001445"
     CDS             18329..19198
                     /locus_tag="ACHDPO_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369075.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            19208..19883
                     /locus_tag="ACHDPO_001446"
                     /pseudo
     CDS             19208..19883
                     /locus_tag="ACHDPO_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            20089..21753
                     /gene="alsS"
                     /locus_tag="ACHDPO_001447"
     CDS             20089..21753
                     /gene="alsS"
                     /locus_tag="ACHDPO_001447"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFN3369076.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            21766..22476
                     /gene="budA"
                     /locus_tag="ACHDPO_001448"
     CDS             21766..22476
                     /gene="budA"
                     /locus_tag="ACHDPO_001448"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFN3369077.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            22606..>23027
                     /locus_tag="ACHDPO_001449"
     CDS             22606..>23027
                     /locus_tag="ACHDPO_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFN3369078.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEID"
BASE COUNT         7574 a         3989 c         4811 g         6653 t
ORIGIN      
        1 ttgtaaattg aatcctgcaa taatcaatta ctttttcatt atttctagat taaatgaata
       61 aactctcatg ccattatctc taaaaaaaaa gtttttcccc ctaatttttt tagatagaaa
      121 attgtatagt atgatgagag aaaaagtagt ttgggggaac gttaatgaga agaaaagcag
      181 taatcgatcg gctttattta tttttttggt tttttcctat cgttttgcta ccttttacat
      241 gggtaaatgc tgttgtacaa ggtgcggaga tattaggcct gatccaagga agcggattag
      301 tggtttctag gaattttcca gctttgactg ttttctattt agtgataagt gtaggtctct
      361 tattaccaaa atctctgatc aatcactaca attggcagct gctttacttt tcttgcttat
      421 tagtatttac atctatgttt tctttgctgc ctcgcttgat tatcggccct aatggtttga
      481 gcgagagtgg attgaaggat tcagcttatt cctccatgta tttcttgacg atcaaaccat
      541 ggttctattt agtaattgcc tcatttattc ttgcaacatt tttttacttc tggacagaaa
      601 tcaggataaa aagtgaacga tctgtatcta taaaaaataa ctattgatgg tggatcatca
      661 gtaaaaaagc atatgagctg cgtaaaatgc atgtttctca tatgcttttt ttattattat
      721 gtaaagaatg cgaaaaacgt ttacatgatt tttacataac ttaactatat ttttacagca
      781 accatacgag ggatttacag tcgactgata aactttagtt gtaaataaga aaggagcaat
      841 aaaatgaaaa aagtattgtt tactctaggt atgatgggaa ttcttttagc cggatgcggc
      901 tcaggatcag gaaatacaga tggctctgcc acacaaaata attcaagtga ctcaaatgaa
      961 caagtaaaaa tcgttgcggt aggttcgaca gcattacagc cgttagtcga tgcagcacaa
     1021 gaaagctttg tacaagaaaa tccaaattat caaatctctg tacaaggagg aggaagcgga
     1081 actggtttga gccaagtcga agctggagca gttactatcg gaaactctga tgtatttgca
     1141 gaagaaagag acggagttga tgcttcaaaa ttagtggatc ataaagtagc agtggtcggg
     1201 atggcaccaa tcgtcaataa agatacagat gtcaaagata tcaccaaaca ggaattgatt
     1261 gatatcttta caggaaaaat cactaactgg aaggaagttg gcgggaaaga tcaaaaaatc
     1321 aacgtcgtga accgtgcaaa cggcagcggt acccgcgcga cattcgaaaa atggggactg
     1381 gatggtgcta cccctgtgca gtcccaagaa caagattcat caggaacagt tcggcagctg
     1441 gtaagtcaaa caccaggagc aatcagctat ttagctttct catatctcga tgattccaca
     1501 caagcactaa gtatcgacgg tgtagaacca aaagaagaga atgtagcaga taacagctgg
     1561 ggaatctggt catatgaaca tatgtacacg aacggaaaac cttcccctga agtccaaaaa
     1621 ttcttagact acatgatgac agaagaaatc caagaaggac ctgtcaaaga attgggctat
     1681 ttaccaatca caatgatgga agtagaacgt gatcacgaag gaaatatcaa ataactagca
     1741 gataaacatg ccacggtagt cgttactatt aaggaaaaat caactatgtt tccccacata
     1801 tacatttttc ctttaattgt gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat
     1861 accgagggtc agctgattga acaccgttta ttcgaaaaaa agagctacga catagaactg
     1921 tcgtagcttt ttttttgcta tatgacagga atgaaaggtg tttgcaagct taatgtgagg
     1981 aacactttcc atatctgttc tatactggat aggagaagtt tggaaatatc cagaaaacga
     2041 aatcaatcga ggtagccaca tgaagaataa atggataaat cgaagtaaaa aaaagaaagt
     2101 aacacaaaga tcatcagata aagtcatccg tctttttcca tcgtataaag aaggattaac
     2161 ggcagatcaa gtcaaggaac gaatagaaaa aggtgcagca aataattcag tcgatcccac
     2221 attcaaaaca aatcagcaaa tcgtattgga aaacatattt acgtatttca atttgatctt
     2281 tcttatctta gccattttgc tttgtttagt agaatcctat aagaacttga cttttttacc
     2341 agttatcata gccaatacag gaatcgccat ttttcaggaa attcgatcca aaaagatctt
     2401 ggacgaacta aatgttttaa atacagcaaa agtcaatgtc atacgagacg ggatagaaca
     2461 aacaatagat atagaagacc ttgtaataga tgacattgtt attttagaga ctggacatca
     2521 aattccagca gatgcagagg tcgtggaagg gaaactgcaa gttaatgagg ctttattgac
     2581 aggcgaagca gatgaaataa ccaaagaaat aggcgatcca ttaatgtccg gcagtttcat
     2641 tgtttccgga aaagcttacg cccgattaga caaagttgga gcagattcgt atatttccca
     2701 gctgacagtc aaagccaaga caatgggaga aggagaacag tcggagatga ttgcttctct
     2761 taatcaattg atcaaatgga ttgggatcat cattattcct atcggtatcc tgcttttttc
     2821 tcaaagttac ttttttaatg gaaacacgat caaagaaagt gtcgttgcaa tggaagcagc
     2881 attgatcggt atgatacctg aaggactgta cttgctgacg acgattgcat tagcattaag
     2941 tgcgactaaa ctagcaaagc aaagagttct tttacacaat atgaaaagca ttgagacatt
     3001 ggcaagggta aatgtccttt gtgtagataa aacaggaacg atcacagaaa ataaaatgtc
     3061 tgttcaaaaa gtgatcgtct ctaaaaaaca agaaataatc agtcagtcag atcaattgga
     3121 agcatgcatt gctgactatg caaaagcgat ggcaggagac aatgcaacaa tggaagctgt
     3181 taaagcatat tttacaaaaa ccactgatca atcctatcac catgttattc ctttttcttc
     3241 tgtccaaaaa ttcagcagtg tagcgttggc agacaaggtg tatgttttag gagcgcccga
     3301 aatggttttg cgcgatcaat tgccggaata tgcggaagag tttgtttctt tcgctgaaaa
     3361 aggctatcgc gtgttggtct ttggtgtgta cgatgggatt cttgaagaac cagtattgac
     3421 agaagcagtc acaccattag gctatattct gattgctaat cctatcagaa aagaagcaag
     3481 agccacattt gattacttca aaaaacagca agtagccatc aaagtgattt ctggagataa
     3541 tccgctcacc gtatccaatg tagctgtcca agcagggatt tcacatgctg atcagtacgt
     3601 tgatgcatct aaattatcag aagaagaata tgaagcagct gtcgaaaaat atacagtttt
     3661 tggacgcgtc aagccagaac aaaagaaaat cttcgttcaa ttgctaaagc gtcgtaacaa
     3721 tacagtagct atgacaggtg atggcgtgaa tgatattcta gccatgaaag aagcagactg
     3781 cagtatagcg atggcttccg gaaatgaagc cgccatgcag gcctcacaag tggtcttact
     3841 tgattctgac ttttcacgca tgccagaagt tgttgcagaa ggacggcgcg ttgtgaacaa
     3901 tattgagcga tcagccagct tgtttttagt gaagaatatt ttctcctttt tgctctcact
     3961 gttttcagtg atctttgctc tgacctatcc tttagaacca tcacaaatca cattgattag
     4021 tttgtttact atcggacttc catctttctt gcttgctcta gaagaaaaca aaaagcgaat
     4081 cagagggaaa ttcatcatga atgtgatgga aaaagctgtg ccaggtggac taacagatat
     4141 gatcgtagtc ggtgcgttgg tgatctgcgg ggtgactttg aatctaaata aaacagatgt
     4201 ttctacagca tctaccatgc ttttgattgc agtagggttc ctcgttctct ataaaatctg
     4261 ttcaccgctg aataaattca gaagtcagat cattcttttc tgtgctagcg gtaacttttt
     4321 ttcggtcatc tttttgcata agctgttttc aatcaccggt atctcagctg tatcactttt
     4381 gctgttgagc attctatttt tctcggcaga ttcgattttt aggcatttga ccacattggt
     4441 agaatatttg tttgaacgta aaaatgaaaa agagcaaaag ccgtttagtc gcgtagttaa
     4501 aaaatttcta tcgatattta aacgagaaaa ttgacgaaaa gtatctcaaa aaagagtaaa
     4561 aaagaacaac cactcgtgta tctttcgaag caggatgagt catccaactt taaaacgcac
     4621 gagcagttgc tcttttttac attttcggaa tggtaacggt gaaagtcgaa cctgttccaa
     4681 gatgactgtc tacagtaatc gtaccatgaa ggagttgcac gtagtctttt acaatcgcta
     4741 accctaatcc ggtcccgcct gaatgccggc ttcgcgcctt gtctacgcgg taaaaacgct
     4801 caaagatccg ttcctgatcc tcaatgtcga tacctatacc aaagtcttgg acagaaaacg
     4861 atagatcatc tgttgcctga tagcggataa taatctcgct gtcgcttttt gaatattgga
     4921 cagcattttc aatcagattt ttgataattg gataaaggat atctgtttta gtagtaaatg
     4981 gttcgttctt tccaatcaat cgaatcgtca accgtttctt ttcgatgatt ggctgataat
     5041 tttgaacgat ttgctggaaa taaggttctg tataaattgt ctggatctcg taagaattct
     5101 cgccatcttt tgacagctgg atgatttccc gaatcagttt atctaaccgg atcgcatctt
     5161 tttgcatgat ctcaagaaaa gaagtcagag tttgcgggtc atcttttgca ccatccagta
     5221 aagtctcggt aaaaccaatc agtgaagtca caggagtttt taattcgtga gagacgttgc
     5281 caacgaaatc cttttgtagc ttttctaaac gtcgcacttt cgttaagtca tacgccaccc
     5341 ctagaatctg tccggtacct tctgaattag taaagtagcg caaactcaag tctaatgtct
     5401 gccgaccttc tgtaagggtg atctcctgat ggatcagcgg atgctcagga gtcacttgat
     5461 gaatcagctg aatgagtttt ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat
     5521 agcttaccac gtttaaatgt agctgcatct ttggattaag cagtagtaaa cgagaatcag
     5581 catcatcaat caggaatacg ccaatcatca gttcgttcag taacgtatat aattgctctt
     5641 ctgtggtagt atacgcccga tacatcttac tcatttgttc gctcaacgca ttgatcgtct
     5701 gatacaattc ttcccattga tcgggtgttt gcatgattac ttccgcctga ttaggatttt
     5761 gcaccatttt ttttagtacg ggcagcacgg ttttcaatgg ctggtttttt tgatagatca
     5821 gataatagat cattcctgca agaacaagga agaaagacag aaagaagaaa aagacccaac
     5881 ggcgaaaact ctcagttctc ggtaaaaaac cgcttgtcgg ttctgcgata cgtaaaatgg
     5941 cttctaactg gccacttttt ttgactggta atgcgacata taaaagatcc ccattcaaag
     6001 tagtactttt gcgcaaagcg ctacctaggt tcccaccatt caatacggct ttgatttcgg
     6061 gacgggagtt tcgctgttca ttcaatgttt cattgtttgt gtcaaataag atctttccag
     6121 tagcatccat taaagtaatc cgttcgttcg actgatggac gaattcttcc aaagcagttt
     6181 tgttttgcgc tgcttggagg ttttcgacat ctaattgccg gatcagcagt tgtgcttttt
     6241 ttgtcaggta gctttcttgc tgttccacga tctgctgttg aaaataatgg gaaatcaatt
     6301 gccagccacc aaaaaacaaa ctaactaaaa gaataagaaa gaagagacgt tcataaattt
     6361 ttttccattt catcgtttgg gttcctgaaa cttatagcca aatcctctaa tagtcaccaa
     6421 gtactttggg tgttttggat ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc
     6481 tacgattcgg ctttgtcctg cgaagtcaaa attccaaatg cggtctagca atgtgtctcg
     6541 gtcgatcaca cggtcttttc gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt
     6601 tagttcaatc agatggtcgt ctacggtcac ttgataattg gtcaaatcag cagtgatttg
     6661 tccaatcgat agatattcag gctcagcttc atcttttgat tgcttacgag gttcaattcg
     6721 tctgaatatt gctttcatac gggctaatac ttcgcgagga ctaaatggtt tggtcaaata
     6781 gtcgtcagca cctatttcta ggccaatgat ccgatccact tggtcatctt tagccgtcag
     6841 catcaaaatc ggtgtttcat ttttttcttg acgcagccgc tgagtgatct ccatgccatc
     6901 catcgttgga agcatcacat ctaaaatgat gaaatcaaat gattgttcta atgctaattc
     6961 taatccttcg cctccatctg tggcactggt taccttgtag ccttcttttt ccaaattgaa
     7021 cgtcaagagc gttacaatag aaggttcatc atcaacaact agtatttttt tcattcaaat
     7081 ctcctttaaa taggtttcat tctgtttata ttttagcata gaatcagtac aaagggctat
     7141 tttacaaaag aaataaatgg tataatagga aggcactttg ctgaatagaa aggaagagca
     7201 gtcaatgatt ggaatcagtg catgtttagg cggtctggcc tgtcgctatg atggacagaa
     7261 aaaagaagta ccagaattga tggaactagt tgaaactgga gaagctgtca tggtctgtcc
     7321 agaagtgatc ggcggattac caattcctag agatcccgct gaaatcattg gtggaaatgg
     7381 attcgatgtg tggaaagatc aagcaaaagt atggacgaca agcggcgaag atgtaacgga
     7441 agcgtacaaa aatggcgcga tcaaagccta tcaaaaattg caggaaaaac acattgatct
     7501 agtcatcatg aaggaaaaaa gcccttcatg cggaacccat tcgatttatg acgggagttt
     7561 ttccggaata aaaaaaaatg gtgccggagt ggctactgct tattttattc agcaaaaaat
     7621 gactgtgctc tctgatgaag aatggctgaa aactagaggt gagcagaatg gaaatcgaaa
     7681 agaccaatcg aatgaacgcg ctctttgaat tttattcgac cttattgaca gaaaaacaaa
     7741 tgaactacat ggaattatat tatgcagatg atttttcatt aggtgagatc gcggaagaat
     7801 acgaagtaag ccgacaagca gtatatgaca atatcaagcg gacaagcaag atcttggagg
     7861 attatgaaaa aaaacttcat cttttttcta attatattgt tcgagaacag gtattggaaa
     7921 atatgactgc atatattaca gataagtacc cggaagataa aaaactactt gaatatgtac
     7981 agcaaattca agcaatcgaa gaataaataa aaggaatgaa gaaaatatgg catttgaaag
     8041 cttaactgaa cgtctccagc aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga
     8101 agctgacgta aaagaaatga tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa
     8161 cttgcaagta gtcaaagatt ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt
     8221 gctggaaagt ttatcacctg cacaacaaat cgtaaaaatc gttgatgaag aattgacgat
     8281 cacacttggt tctgaaacag cagagttaaa taaatcacca aaaataccaa ctgttatcat
     8341 gatggctggt cttcaagggg caggtaaaac gacctttact ggtaaattag ccaattattt
     8401 aaagaaaaat gaaaatgctc gtccgctcct aatcgcaggg gacgtatatc gaccagctgc
     8461 gatcgaccaa ttgaaagtat taggtcaaca gctagacgtt cctgtatttg atatgggaac
     8521 tgaagtcagc ccggtagaga tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa
     8581 cgactatgta ttgatcgata cggcaggacg tctgcatatc gatgaaacat tgatggatga
     8641 gttgaaacaa atcaaagaat tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat
     8701 gactggtcaa gatgccgtca acgtagctga tagcttcaac cagcaattag gtattacagg
     8761 ggtcgtcatc actaaacttg atggggatac tcgaggcggg gcagcactat cgatccgctc
     8821 agtgacaggc gcaccaatca aattcatcgg ttctggtgaa aaattgactg acttagaagt
     8881 attccaccca gatcgtatgg ctagccgtat ccttggtatg ggggatatgc tgacattgat
     8941 tgaaaaagcg cagcaagact atgacgagaa aaaagcggaa gaacttgcac agaaaatgcg
     9001 ggaaaattca ttcgatttca atgactttat tgaacagctt gatcaagtga tgggtatggg
     9061 cccactggaa gatctaatca aaatgatccc aggaatgaat caagtccctg gaatcgaaaa
     9121 cgtcaaggta gatccaaaag atgttgaacg caaaaaagcg atggtttatt ctatgacgcc
     9181 agcagaaaga gcaaatcctg atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg
     9241 ttctggaaac agtgttgttg aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa
     9301 aatgatgcag caaatgtcca aaggggatat gaacatccca ggtatggacc aaatgtttgg
     9361 ttcaggcgtc aaaggaaaac taggcaaaat ggcgatgaat cgaatgatca agaaaaataa
     9421 gaagaaaaag aaaaaacgga aataagatga aaaaaacagc ttcggtacag actgaaaatg
     9481 tctactgccg gagcttttct atcagcaatt tttattcttt actaatacaa ttactctaaa
     9541 cgaagaggtg gcacagatga gatgtccgtg gagtgaacaa acagaaagta tgcggcaata
     9601 tcatgatact gtctggggtg ttcctgaata tgatgaccaa aagctgttcc gaaaattgat
     9661 gcttgatatt aatcaagccg gattgagctg gcagacgatt ttaaataaaa gtgaagcatt
     9721 cgatgaagca tatgatcgat tcgatattaa aaaagtcgca aattatggag aaacaaaaat
     9781 cagtgaacta atggaaaaca aaggaattat tcgtaaccga agaaaaatcg aagcagccgt
     9841 ccaaaacgcc aaagcagtct tgaaaattca agaagaaatc ggcagttttt cagagtatct
     9901 ttggtcgttt tctaatggaa aaatcgttga ttcttcttat cattcacaag aagaagtccc
     9961 aacaacaagt cctctttcag atgaattagc aaaagatcta aagaaaagag gatttaaatt
    10021 tatcggaagc acaacaatct atgctttttt agaagctgtc gggatcatca atgatcacct
    10081 tgacagttgt ttccgcaaag aagaggtcgt acgtatcggc agaaagggcg aataaagcat
    10141 gcgaaaaatc atattttatg gtgctataag tttagatggc tatttggcaa cgaaaacgga
    10201 tgatcttcaa tggctttttg acactccaac aggtaagcaa accacttatg aagcttttta
    10261 tgaaacaatc gatacgacca tcatgggcag aaaaacttat caggaagcaa aaaaatattt
    10321 ggagaccgaa gcaatttatc cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt
    10381 acaattgcca gatgctgagg tcgtaaacga agatcctgtt gcttttctaa aaaatctaca
    10441 aatgacagaa ggaaaagata tctgggttgt gggtggcggt cgattgatca aaccgctatt
    10501 ggaacatcaa atgattgatg aatggtatat ccagattacc cctgtattat taggggacgg
    10561 gattccttta ttccaaaaag gaacatatga agcgcgtttt gaaatgctag acacgacacg
    10621 attcggtgaa tttatcgaat tgcattatgt acgaaagtag aagtaaataa aataaaaaag
    10681 gcaactatat gcagaaatgt cctgtacata gttgcctttt ttattaccgt tatgcttttt
    10741 actctgttaa tttgttagaa aaatctagat acgcatctaa aatcgtttgg aagaaactta
    10801 atgttccttc aacgatatta ccattttcat caattagatt cgcaacgttt ccgatatatg
    10861 cttccggttg ctgcaaggtt ggcacattca aaaagacaag tgattgtcgt agatggtggt
    10921 ttgcgccaaa gccgccgatc ccacctggtg atgcagtaac gactaaacct ggtttatgat
    10981 cccaaacact gtgtccataa ggtcttgagc ctacatctaa agcatttttc aatactgctg
    11041 gcacagaacg gttgtattca ggagtaacga aaacgacacc gtctagtccc ctcacttcct
    11101 cacgaaaacg agtccattca gcaggagcct gttctggagt ttcgagatcc tcattgtaaa
    11161 atggcagatc atcgattttt acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa
    11221 aagcttctgc tacttttttg ttgtaagaat cttttcttaa actaccaata aaaaatccaa
    11281 ttttttttgt catacgattt ttcctccttc aaactatcta taacaatctt acaaaaaata
    11341 agtaactgga gcaaataaaa acacttactg acaaaagcta catagaagat agattactta
    11401 tttttaacaa aaaagaagtc taaaatcttc tatttcctaa aaaaaatcga atttaatcaa
    11461 gctgtaaaga aaaaaagctt tacagggtaa aaaaaaactg ttacactaca tcttgtgaat
    11521 aaaacaatgg aggtggaaat aaataatggc agttaaaatc cgtttaaaac gtatgggttc
    11581 taaaaagagt ccgttttacc gtatcgtcgt agctgattca cgttctcctc gtgatggacg
    11641 tttcatcgaa actgtaggta cttacaatcc tttgaaagac cctgcagaag tagttttaaa
    11701 agaagactta gttcttgact ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa
    11761 catcctttca aaagaaggcg ttatgcaaaa acaccacgaa gctaaattct caaagaaata
    11821 aggtgaccgg atatgaaaga tttaagcgac ttagtcttaa caatcgttcg tccgctagtc
    11881 acttatcctg atcaagtcaa gttagacgtc gtagagtcga aagactttta cgagtacaat
    11941 ctaacagtgg ctcctgaaga tattggccgt atcattggaa aacaagggcg tgttgctaaa
    12001 gcaatccgca caatcgttta cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat
    12061 atcatcgatg ataaggaaaa gtaaataaac gtgctgtact cgaattttcg agtgcagctt
    12121 ttttgttttt ttattaattg aagaaatgat tatttggcaa aacaagcaag aaagcgtatc
    12181 cttataggag gagggagtga acagccaatg agaaagaaaa tgttatttat tccatttgct
    12241 ctattgttaa gcgcttgtag ttcggttact caagaatcag acaatacaca tctatcaagc
    12301 agtatatctg aaactgttac cagtccagaa aaaagtagta ccaaaacggc taccaccact
    12361 gaacaaacaa tggctacctc aaataatgag aaaaagactg ctttagacca gttgaaagaa
    12421 caacagccaa atgttcccat gcctctagat gtaccagtct cttcaggcta tctcaatatc
    12481 gcagcgacac atacaaagca aggttattct attttatatt acagaacaga tcgtcccctc
    12541 gggttgaatg ctgacgaatt gaatcaagaa acgcctattg caacctatct atatcaatat
    12601 gggtttgctt ctagtcaaga aacaatccaa gttttgcagc cctttgagat cgacacaaat
    12661 ggtcagcaag tggacttagg ttctcgaatc acagggtatc agcaaggtgc agcaggttca
    12721 agttttcttg aatggcaaga aggaaactgg cgtattcgaa tccgtgggaa taatatagaa
    12781 ggccaagatc ccttactatt agctaaagaa atcgtagctt atttggaaga aaacagtcta
    12841 ccagcacctg aacaatttgg taaaattact gttgatatgg gtgatacgac gaatcgagcc
    12901 gtagaagtaa gctggcaaga accgaaaaat gcctatacga tcactcatca agatcctatg
    12961 tctgcgttga agatggcagt ttctatgaag aggttgtgaa atcagcgcgc tgatctgagc
    13021 ccatcattta actccaagtc acaggaagta atcaaaaata gcacgccgca tttttgcata
    13081 attttggctt aataccttaa aagaaaacta gaattgcctc ttcacacatg ctaaaataaa
    13141 acagacaaaa aagaaatggg gatataagtt gactgaatac ttgaatgtag gaaaaatcgt
    13201 aaacacacaa ggtatcaaag gcgaagtccg tgttatctca acaacggatt tcccagaaga
    13261 acgttacaaa aaaggaacgg tgttaacact attccaagac ggaaaagcac ctgtggaatt
    13321 aacagtcaaa agtcatcgca aacataaaaa ttttgactta ttgagttttg aaggacatcc
    13381 ttctatcaat gatgtggaaa aatatcggga tggcatatta aaagtgtcaa aagacaactc
    13441 tgtagatcta gctgaaaatg aattctatta ccatgagatc atcggtctgc atgtattaga
    13501 agatggaact gagttaggta aagtaaaaga aatcttgtca ccaggtgcca atgatgtttg
    13561 ggtcgttcaa cgtccgaaaa aagctgatat attgcttcca tatatcgctt ctgtcgtcaa
    13621 agaagtcgat ttagaagctg gagtggtccg tgtagaaatt ccagaaggac tgattgacga
    13681 tgaagattga tgtattgact ttatttccaa gaatgtttga aggtcctatg ggggaatcca
    13741 tcatcggtaa ggctgtagat aaaggattat tagatatcaa tatctctaac ttccgcgatt
    13801 attcagataa caaacatcag acagtagatg attatccata cggcggtgga gcaggtatgc
    13861 tgctcaaagt ccagcccatc tatgataaca tccaagccat tgaaaaagct gcaccggatg
    13921 tcaaaaaaag agtaattctt cttgacccag ctggtaaacg attcgatcag aaaatggcag
    13981 aagaattttc acaagaagaa cacttagtat tcatttgtgg tcattatgag ggatatgatg
    14041 aacgtatccg cacattagtg acagatgaag tttccttagg agattatgtc cttactgggg
    14101 gagaattagg tgcgatggtc atgatcgatg caacagttcg gcttttgcca gatgtgttag
    14161 ggaatcagac ttcagctcaa acggattctt attcaaccgg tttattggaa catccccaat
    14221 atactcgccc ggcagaatat aaagggatga aagtaccaga agtattgaca aatggaaatc
    14281 ataaattgat tgaagaatgg caattaaaag aatcactaag aaggacctat caacgtcggc
    14341 ctgatctttt ggaaacactt gaatggacac ctcaaatgac gaaattttta gaagaaatca
    14401 agaaagaaga acaagaaaaa acagcagatg aagccaagtg actttttcta aaatattctt
    14461 tacagtaggt tgataatatg ttagtatttt atggtgagtg caaaagcact taactattac
    14521 gatattccgc tatgagaaaa gctcataaga atatttggaa taaggagaag aaaaccatga
    14581 atccattaat cgaagaatta acaaaagaac aattacgttc tgacatccca gcgttccgcc
    14641 ctggtgacac tgtgcgtgtt cacgcaaaag ttgttgaagg tactcgtgaa cgtatccagt
    14701 tatttgaagg tgttgttatc aaacgccgcg gtgctggaat cagcgaaact tatacagtac
    14761 gtaaagtttc taacggagtg ggcgttgaac gtacattccc attgcataca ccacgtgttg
    14821 caaaaatcga agtagttcgc tacggtaaag tacgtcgtgc aaaattgtac tacctacgtg
    14881 cattacacgg aaaagctgct cgtatcaaag aaatccgtcg ttaatcattg ttatcagact
    14941 gagaaagaac ccttggtatt caagggttct tttttcttag catgtaattt gaacaccctg
    15001 atccagtttt tttctttaat tattggtagg ggagaataat ggattagaat aaatctacct
    15061 ataagtagta gtaaaaaaaa gagcactatg ataatatctt tcttaagagt aaccgcttta
    15121 ataaaaaatc cagaatattc taacataaat ggagtattct tagaatcaaa aggagaaaga
    15181 agatggttta tacttatacg gagcaagaaa aaatgaaagt ttgagacaca ttcatgaatg
    15241 atggaaaagt aaaacaagta ccaagttcaa caaaaaagaa aaacatccta ttgaaagaag
    15301 tcttgaaacg ctttgaccat ggagtgactt atacagaaac agaggttaat tcgatactgc
    15361 tgaacgtatt ttctagtggc gattatgtcg aacaaagacg ttatctaatc acatttggct
    15421 ttttcaaaag aagttcagac ggtcgggcat atcagatgat gggaattgaa aattagaagt
    15481 tttaatttat actcattgaa aaaagttcaa gtatgcgata ttggttctac accgcatact
    15541 tgaacttttt ttgtcatctg tatctataat acaaagccaa gaacgttatt caaaatatgg
    15601 atagctatga taaaagctaa tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc
    15661 gttccaggag cgtacatgaa aaaatcaatt ggatgcgtta catgaataaa gataattctc
    15721 ttttatttgt acgaataaat accaaaacgt acctcctaaa attagattca aagaagatag
    15781 caaagaggaa aaagatagtt ctgcagcagc tatagcggca tgtggattgc tagaactttc
    15841 caaacaactg cctgtttcag atcctcgtca tttcgattac gaagagatag caatcaaaat
    15901 cttggaagaa ttacagaaaa actatacaac gaaacgagtt aacggatcaa acggtctgct
    15961 tctccatgcc gtttatgata aaaacagctt aaaaggtgta gatgaatgtg tgatctgggg
    16021 cgattacttt tatgtagaag gaatcactcg tctagctaaa acatggtact gttactggtg
    16081 atgtataaga gaagaggagg attcatataa tgaagcgatg gaaaaaaatg atgattggat
    16141 caatagtttt aggaatgtca ctcgtatttg gtgcttgtgg taatcaagaa gacagtagtg
    16201 aagaatcagc aaatgaaatt accgtttcga catggaatta tgaaacaaca cctgaattca
    16261 aagcgctctt tgaagcattc gaaaagaaaa cgggaatcaa agtgaaagca gtagatattg
    16321 cttcagatga ttatgatacg aaactcacca cgatgctttc ttctggagac acgacagatg
    16381 tattgacgat gaaaaatctt ttgtcgtatt caaattatgc tttacgagat cagttagtcg
    16441 atcaaacaga acgaattaga gaattagaca ctgatgctgc tgaagaaaca tatgaaatgt
    16501 atgatatcga tggaaaaaca tatgcattgc catatcgaac ggacttttgg gtactatatt
    16561 acaataagaa aatgtttgat gatgcaggaa tcgaatatcc aaaaaatcta acttgggacg
    16621 aatatgaaga tttagcaaaa aaacttagta aaaatgacgg acaagtttac ggagcatatc
    16681 aacatatctg gcgttcgaca atccaagcta ttgcagctgc tcaaaacgag gcgaatcttg
    16741 ttgaaccaga ttatcaatat atgactgatt attatgatcg agcattgagg atgcaaaaag
    16801 aaggcgcgca gatggatttt ggcacggcta aatcaacgaa agtaacctat cagtctcaat
    16861 ttgaagaaca aaaagcagca atgatgtaca tgggaacttg gtatatggct ggcatactcg
    16921 caaacaaaga agcaagtaag acagaagtag aatggggaat tacagctatt cctcagaaga
    16981 aaaaaggaga atcggtcacg acgtttggct caccaacagc atttgctgtc aataaaaact
    17041 caaagaaaca aaaagcggcg caagaattta ttgaatttgc agccagtgaa gaaggagcaa
    17101 aagtattagc aggagtagga gtagttcctt catatcgtac ggatgagatt gatcagcttt
    17161 attttaatct cgctggaatg ccaacggatg aaatttctaa aaaagctttt tctcctgatg
    17221 aaatcaaact tgaatttccg attgatacgt atgggcctgc aatcgataag attttacaag
    17281 aagaatatga cttagttttg gttggagatg aaacgccgga aaaaggaacg gtaaatatgg
    17341 agaaacgtgt agctgcggaa aaagaataat catgaaagga gagaagccaa gagataaaac
    17401 actcttggtt tcgtcatcga aatggagaat agtataaata agaaagctac aaatcatttg
    17461 cgtagaaaac gaacgtggat cgcttattcg tttatcgccc cgaatttcat tggttttttc
    17521 gtttttacat taataccaat cctgttttcg cttgtactag catttatgaa atgggattct
    17581 ttttcaacgc cagaatttgc tggactagat aactttcgta aaatggccaa cgatgagaca
    17641 ttttggattt ctttgaaaaa tactttttta tataccgctg ctgtagtgcc tggcacactt
    17701 gtttgttcgt tagggctagc tttactacta aatcagaaaa ttagagggat gaagcttttt
    17761 cgtacgatat ttttctttcc gtatgttact tccttagtag caattgctgt tgtttggaat
    17821 atgttgtttc atccaacagt gggacctatt aatatctttt taagacgatt tattgaacat
    17881 cctccaggtt ggacttcaag ttcaaattgg gcgctttggg caattgtaat tgtcagtatt
    17941 tggcgaggga tgggttatta catgattcta taccttgcag gactacaaag tatccaaaaa
    18001 gaactatatg aagcgtcttc gctagatgga gcaaaccgtt ggaaacaatt tttgaatgtg
    18061 acattacctt cgttgagacc aacaaccttc tttgtaacga tcatgcttgt catcaattgt
    18121 ttcaaggtgt ttgaccttgt gcaagtgatg acggatggcg gccctggtcg agcgacaaat
    18181 gtgctggttt accaaatcta caatgaagca ttcaaaaaat ttgattttgg ttatgcttca
    18241 gctatttcac ttgttttgtt cgtaattgtt ttgggcgtta cggttgttca attttcttgg
    18301 aataagcgtc gtacttagga ggtgtgatat ggaagagagt gttcgaaatg aaagaaaaaa
    18361 agcaaaaatt cgttcaaaaa acatgccctt tattcaatgg ttgggtatga ttctgctgat
    18421 tgtattagct ttattgacga tcattccttt tttatggatg gtttctgctt cattcaaagc
    18481 aaataatgaa gtgttaacga ttccgattca atggatccct aaaacttggc atttagagaa
    18541 ttatctggtt atttggtctc gtattccttt agtgacattt tttaagaata cagctttttt
    18601 aagcgttgtg atcacgttga ttcagttgtt tacttctagt tttgctgttt acgggttttc
    18661 tgaactaaat tttaaagggc gcgatatttt atttttagca tatatcggca cgattgctgt
    18721 cccttggcag tcttatatga tcccgcagtt cattatgatg agaaaagtgg gtttaacaga
    18781 tacgttgtgg tcgttggtgc tattacaagc gttcaatgct tttggtgtgt tcttgttgaa
    18841 gcaatattac agtagtatcc cagattcttt atgtgagagt gcgcggatcg atggcttatc
    18901 agagtgggaa atctatcgca agatcatttt acctcttaca aaaccggcga ttgccagttt
    18961 gacgatcatc acattcgtta atacatggaa cgattatatg gggccattca tttatttgtc
    19021 ttctacggaa aataaaacaa tccagttagg gttgaaaatg tttattgggc tatttgatgc
    19081 agagtacgca ttaatcatgg ctgcctcagt tgtttctgtt cttcctgttg cttttatatt
    19141 tttagcgatg caaaaatatt ttgtagaagg gatcgcttca tcaggaatga aggaatagga
    19201 ggtgattatg aaagagcagc gttttgacaa aaatgtttat atggaattct tttattggtt
    19261 gtatcaatca ttggcaagta gcctttgttt ttggtgtgtc aatatcttgt atatagcagc
    19321 tgcgttcctt ttgtcgatag atggaaggaa tgtcttttcc tttatttttt ctttactttt
    19381 tattggtcca ggttgcatcg tgatgatagg tatgacagaa gaattagcaa aagaaaaaag
    19441 tttttcacca gtacgtttgt tcataaagac gtttcgccaa ttttggctaa agggattttt
    19501 ttattggcta tttgcttgga tagttagtgt gataatgatt tttgattgtt tcttttttat
    19561 acgtttttct tatggaaaat ggttgattcc gttgtttgtt ttacttgctt gttttacttg
    19621 cttgtttatc agtttccttt agcatcaact gctggtattt tcaggtgaga aatccagcgt
    19681 cgaaaccaaa tcaagttcta cggatagcgt tctactatac gttgaaaaaa tggtatgtga
    19741 gtttactaga ttttttacta ttgacaagtt tgtttctctt ctttttcgta aagccccaat
    19801 ggtgtattct actaggtcct tctatcgtat ttggtttgat ttacttcaac aatcgtaaat
    19861 tgatgagaac tatggatctg tagactttat aaattgaaac tttcaattaa gaatgacagt
    19921 tttttatgta aaaactgtca ttctttttca ttttttgaaa catatggcta aacaaatgaa
    19981 ataaaacatg ctatactttt gaatgaaaca ggtttagaaa ctgtatcact tatttgtgat
    20041 tatttctaac taataattaa aaataaagca taaaaaggac gatgttcaat ggctgaaaaa
    20101 atgaaacaag gttcgaaatc tgtagtagaa agtttgatta atcatcatgt tgattatgta
    20161 ttcggtatac caggtgcaaa aatcgatggt gtatttaatg aattagagga tcaaggtcct
    20221 gaattaatcg tgactcgtca cgaacaaaat gctgcattta tggcacaagc aatcggacgt
    20281 attacaggag agccaggagt agttatcgca acaagtggtc ctggtgctag taacttagct
    20341 acaggtttgg taacagcgac agcagaaggt gacccagttt tagcaattgc cggacaagta
    20401 aaacgaagcg atctattgaa gttgacccat caaagcatgg ataatgcagc actgttccag
    20461 ccaatcacaa aatacagtgc agaaatccaa gatccagaaa caatttcaga agtgattgcc
    20521 aatgcttatc gtatggctaa gagttcaaaa aaaggcgcga gctttatcag tatcccgcaa
    20581 gatgtagtgg atgcacctgt ccaaggtaat gtcatcaagc cattgagcga tcctaaatta
    20641 ggttctgctt ctgcagatga tatccgttac ctagctgaac gcattagaga agcaaaacta
    20701 ccggtactat tagtaggtat gcgaggatca agtgaaaaag aaacgttagc catcaggcaa
    20761 ttagttgaaa agacagcatt gcctgttgta gagacattcc aagcagctgg agtgatctca
    20821 cgtgaattag aagcgcattt ctttggtcgt gtgggtttat ttagaaacca accaggagat
    20881 atgcttttga aacgaagtga tctagttatt gcaattggct atgatccaat cgaatatgaa
    20941 gcaagaaact ggaatgcgga aaaagatgcg cggatcattg tgatcgatga agcgccagct
    21001 gaaatcgatc cttttatgca gcctgaaaga gaattgatcg gtgatatctc agccactctt
    21061 gatttattga caggttcatt agagcctcaa caagtgtcag aagatgcaaa agaatattta
    21121 gcatctcttc aagcaaaatt aacggagcgg gacattgttc aatcaaaagg agaagcaggt
    21181 atcttgcatc ctttagaagt tattaacacg cttcagtcaa aagtaacaga tgatatgact
    21241 gttaccgtag atgtaggtag tcattatatt tggatggcac gccactttag aagttatgaa
    21301 cctcgtcatt tgttattcag taatggtatg caaacgcttg gtgttgcatt gccatgggcg
    21361 atttctgctg cattggtgcg tccaaataca cagatcgtat cagtttccgg cgatggggga
    21421 tttttattct ctgcccagga tttagaaacg gcggtacgta aaaaattgaa tatcgttcat
    21481 ttgatttgga atgatggaca ctacaatatg gtagagttcc aagaaaaaat gaaatatcag
    21541 cgggcgtcag gtgtagactt tggtccagtt gattttgtga aatatgcaga agcttttggc
    21601 gctaaaggaa tccgagctac aagtgtagag gaattagaaa aagctttaga agaaggattt
    21661 gcgacagaag gacccgtaat tattgatatt ccgattgatt accgtgataa tgagaaattg
    21721 ggagaaacaa tcttaccaga tcaattctat taaggaagtg tcgacatgac tgaaaaaatc
    21781 ttataccagc acgggacatt aggagctttg atggccggct tgatggatgg aacagaaacg
    21841 attgctcata tattagaaaa aggaactctg ggattgggaa cattgcatgg gcttgatggt
    21901 gaagtcatct ttttagatgg cgtagcttat caaggaagat cagatggctc agttgcccaa
    21961 ttagatggaa gtgaacttac cccctatgca gcaattacag attttacgcc agatactagt
    22021 ttttctgtct caaaaactgc agatggagaa caattgaaaa aagacatatt agtaagagaa
    22081 gccggggaaa acctattttt ggcagtgaag ataactggat tattcaaaaa tatgcacatc
    22141 cgtatcatgc cgaagcaaga aaaaccttac agaagactag caaaaatttc agagtctcaa
    22201 ccagaattcc aacaaagcaa tgtccaagga acattagtcg ggttctttac gcctgaatta
    22261 ttccaaggag ttgctgcagc gggatttcac ctgcatttta tcgatgatac acatacattt
    22321 ggcggacatg taatggattt tgaagtggct gaaggaaaag ttgagattag ccgcatctcg
    22381 tcccttgtac agcattttcc agttgatgat ccgacttttg ttcacgaaac gattgattat
    22441 gctgatttag cagcagaaat ccaacaagca gaatagaaaa agacagcgag atgcgttcaa
    22501 ggtgattaac ctgacgtatc tcgttttttt gaggagaaaa cctagcgttt acaaaaaaac
    22561 tgagctataa tcttctccat agatcaaaaa ggagcggttt ttatcatgtg gacagaaaaa
    22621 cagaaaaaag atgcatacga aattttatta ttacagcaac aaggattatt agaagcagaa
    22681 gataactggt tagcaaattt agcaaattca tctgcattgt tgaatgagac tttgcctgag
    22741 actgtctttg caggatatta tttattcgat ggtaatgaat tgattttagg accgttccaa
    22801 gggcgagttt cttgcacacg tatcaagatg ggaaaaggag tttgtggaga atcagctgaa
    22861 aaacaagaaa cattgatcgt tgatgatgtc aaaacccatg caaattacat ttcctgcgat
    22921 tcagccgcac aatcagaaat cgtagtgcca atggtaaaag aaggtaattt aatcggtgtt
    22981 ttagatatcg attgcggagt aacgaaaggg tatgatgaaa tcgatca
//
LOCUS       DAZAOD010000037        22911 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000037 DAZAOD010000000
VERSION     DAZAOD010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.038"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            116..670
                     /locus_tag="ACHDPO_001450"
     CDS             116..670
                     /locus_tag="ACHDPO_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3369079.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(843..1280)
                     /locus_tag="ACHDPO_001451"
     CDS             complement(843..1280)
                     /locus_tag="ACHDPO_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3369080.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1328..2275
                     /locus_tag="ACHDPO_001452"
                     /pseudo
     CDS             1328..2275
                     /locus_tag="ACHDPO_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            2546..2981
                     /locus_tag="ACHDPO_001453"
                     /pseudo
     CDS             2546..2981
                     /locus_tag="ACHDPO_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            2997..3830
                     /locus_tag="ACHDPO_001454"
     CDS             2997..3830
                     /locus_tag="ACHDPO_001454"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3369081.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            4075..5100
                     /locus_tag="ACHDPO_001455"
     CDS             4075..5100
                     /locus_tag="ACHDPO_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3369082.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5238..5363
                     /locus_tag="ACHDPO_001456"
     CDS             5238..5363
                     /locus_tag="ACHDPO_001456"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369083.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            5388..6503
                     /locus_tag="ACHDPO_001457"
                     /pseudo
     CDS             5388..6503
                     /locus_tag="ACHDPO_001457"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            6586..7482
                     /locus_tag="ACHDPO_001458"
                     /pseudo
     CDS             6586..7482
                     /locus_tag="ACHDPO_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            7498..8322
                     /locus_tag="ACHDPO_001459"
     CDS             7498..8322
                     /locus_tag="ACHDPO_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369084.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8354..9664
                     /locus_tag="ACHDPO_001460"
     CDS             8354..9664
                     /locus_tag="ACHDPO_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HFN3369085.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            9812..11071
                     /locus_tag="ACHDPO_001461"
     CDS             9812..11071
                     /locus_tag="ACHDPO_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFN3369086.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11081..11953
                     /locus_tag="ACHDPO_001462"
     CDS             11081..11953
                     /locus_tag="ACHDPO_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369087.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            11965..12795
                     /locus_tag="ACHDPO_001463"
     CDS             11965..12795
                     /locus_tag="ACHDPO_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369088.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            12835..15018
                     /locus_tag="ACHDPO_001464"
     CDS             12835..15018
                     /locus_tag="ACHDPO_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFN3369089.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15079..16299
                     /locus_tag="ACHDPO_001465"
     CDS             15079..16299
                     /locus_tag="ACHDPO_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFN3369090.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16296..17756
                     /gene="gtfA"
                     /locus_tag="ACHDPO_001466"
     CDS             16296..17756
                     /gene="gtfA"
                     /locus_tag="ACHDPO_001466"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HFN3369091.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            17833..18939
                     /locus_tag="ACHDPO_001467"
                     /pseudo
     CDS             17833..18939
                     /locus_tag="ACHDPO_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19261..19470
                     /locus_tag="ACHDPO_001468"
     CDS             19261..19470
                     /locus_tag="ACHDPO_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFN3369092.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMASKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19463..19612
                     /locus_tag="ACHDPO_001469"
     CDS             19463..19612
                     /locus_tag="ACHDPO_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFN3369093.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            19766..20431
                     /locus_tag="ACHDPO_001470"
     CDS             19766..20431
                     /locus_tag="ACHDPO_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3369094.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20715..21800)
                     /gene="xerS"
                     /locus_tag="ACHDPO_001471"
     CDS             complement(20715..21800)
                     /gene="xerS"
                     /locus_tag="ACHDPO_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFN3369095.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22134..22367
                     /locus_tag="ACHDPO_001472"
     CDS             22134..22367
                     /locus_tag="ACHDPO_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HFN3369096.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22364..22771
                     /locus_tag="ACHDPO_001473"
     CDS             22364..22771
                     /locus_tag="ACHDPO_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFN3369097.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
BASE COUNT         7834 a         3431 c         4389 g         7257 t
ORIGIN      
        1 aaactaaatc ccttgatttt attgactttc aaaagtttat atatataagt taatgattat
       61 ggtaaaatat atacataatc attaactcag aatattttta agaagggaaa caatagtgag
      121 ctataatgta caaccgttaa ggacaaatga agagatacaa gattttcagt tttggctaag
      181 aagaacaagt aatccggaaa gagatagttt tttatttttg tttggaatca ataatgggtt
      241 acgtatgtca gatattatag gattaaaagt tggagatata cgaggcaaaa gtaagcctat
      301 tattgttgaa cataaaacag gtaagcgaaa accgattttt atagataatt tgagagaaga
      361 aattttatta tatactgaag gtaaagaaga aaatgattgg ttatttccga gtcggcaaca
      421 aggtcgacat ataacaaggg atcgtgtcta tcagatatat gcagatatag cagaaaaatt
      481 aggacgagat gatataggaa cacatacatt aagaaaaact tttgggtatc actactacaa
      541 gaaaactaga gacattgcta ccttaatgtt tatttttaat catagctcgc aagcaattac
      601 aaaaaggtac attggtataa ctgaagatga aataggagca tcacttcgtg gatttaaact
      661 aggtgtataa tttaaaaatt tttataaaca gtaaagacaa agattaaaag ctatttttat
      721 ctagaacgat tttatttcat aaagttcgcg gaataaaagc tggggttact ggtacttggt
      781 ataggttcgt gttatataaa ctaagtaatt aaataacatt tttaggttgg aaaaggatga
      841 aattaaaaaa agagaatcaa tacggtctca aaaacgcaaa cgctgcggaa taagaaaaat
      901 actgataact caacgtttag cagactatct aatagggata gtctgctttt ttcgtttttg
      961 accatacttt tgaccttctg caaacttcct tgcttttcct ctgtagaact catgaaatct
     1021 gcaaaacgaa ttgccgtttc ctctgtctgc tttttcgcga tatgggtgta tatatcatcc
     1081 atagtggttt taatatctgt atgtccaagt cgaacataca cttctttgac agacgcacca
     1141 gattcaaaga gcagactaca atgggtatga cgaaaaccat gaagtgtgat atgttttaag
     1201 ttattctctt taatgatgat tttcaaattg tgatttacat agtctaaata aaggggctta
     1261 ttttcttctg atgaaaacaa aagttgttca ccatctttta taggtttgat tctcattttt
     1321 agatattatg cccgcacgta ttcatcacat ttctattgtg aatcgcttta ttcgaccgac
     1381 atttgacttt tatcataata tactcggttt aaaattacta atgaaaacaa ttaatcaaga
     1441 cgatcatacc atgtatcacc tgtttttttc agataatcac caccgtgtgg gaactgaact
     1501 gacttttttt gaagtacaag aagggaacaa ccagtttttt ggaaccaata cgattgaacg
     1561 aacgatacta aaagttcctt ccgaagcatc attgcatttt tgggaaatat attttgaaac
     1621 acaaggcgtt tgccattatg gaatcgaatc attttctgga cgacctatct tacgttttga
     1681 agggccagat gcaacacgat tagctttagt tcccttacgc gaatttgaag atattgatga
     1741 ttatttcccg tatgtcacag accagatccc tacagagcat gccattttag gaattgatgc
     1801 cattcaacta cgcgtacaat attccgatgc gactgaacga gagttattgt cggtaggctg
     1861 gtagcacaaa gaatacgtca gtttcttttc gggtcatcaa cgagtgacaa tcttagaaaa
     1921 tcaagacact cagttctatc aagaagttca gattattcaa gatcgtgaga atccagttgc
     1981 cattgaaggg attggtagcg tccatcatgt tgcgtttggc gtagaaaata aatctgattt
     2041 acaacgcatc gacaaacaat tacaagagcg caattttata aattcaggaa taaaagatcg
     2101 tgaatttttt gtatcacttt attatcgtga cccaaatcaa ttattgattg aaattgctac
     2161 aggggaagga aacctagatg caaaagcgta tgaaaatcaa agtccacgct ttgaagaaat
     2221 tcctttattt ttaccgcagt acttaaattt cattcgtgaa caagtggagc aataattagc
     2281 taatcaaatc catgacgaag agtaagaggt tgactcataa gtcaaaaaat aaagaaaaac
     2341 gcatcaaatc cattctaaag aatgttgatt tgatgcggtt cctattttta taaactatca
     2401 ttttcgacta ataaaactac ttatgagtca gcctctcttt ttttcttgat ttttatacct
     2461 ctttctaggt aaactaaaca tctgccaaaa ataccgtgtc tcattgaaac attctcaact
     2521 atttcaaaat aaaggggagt accaaatgaa cgagtatatt gaaattatcc acgcaagaga
     2581 aacaacttaa aaatgtcagt ctcaaaattc ccaaaaataa aattagtatt tttaccagcg
     2641 tatctggttc aggaaaatca tcgattgttt ttgatactat tacccaagaa gctggtcgtc
     2701 aactgaatga cacctatgat agttttaccc gtttattttt acctaaatac agtcgtccag
     2761 aggttgatga gattgataat ctttctacgg cgattgtggt caatcaaaag aagattggtg
     2821 gcagtgcgcg ctcaacgtta gggacgatta ctaacatcaa tgcgttattt cgtgtgttgt
     2881 tttcatgttt tgcaacacct agtttaggat atgcaaatgc ttattcattt aatgatccta
     2941 gtggaatgtg ttctgtctgt cagggaatcg gtaagacgat tgcattttta ataggattgc
     3001 tttatttttc ggctattgat aatgctgatt ttgtattttc tgatccattt accgcagaag
     3061 ttttgtctgg aattgaggaa caggcaaaga atcatggtta ttttgtattg gtgcataatg
     3121 ttaattcagc agaagatgtt aaaactattc agagaaattg gcgttttgag gggttcattg
     3181 ttgttggtgt acgtgtaaaa gaatttttgg aattaaataa cgtttttgat ggtcctgttg
     3241 tttatattga tacgcatctt tcaaaagaga cattaagaga acttgaacaa caaatgaatc
     3301 gtttatttgt aaatacaaat gattaccaag ctagtacatt ggcagtggaa catttgattc
     3361 attatggtca tgagaaaata gcgtttcttt cttttgacta cattgtaggt gaaccaagtg
     3421 ttattcaaga acgacatcaa gcttatatcg atacattaaa gaaatatcat ttaaccttta
     3481 aatcgcattg gatatataac aactctgaat ttgagcgaat ttatcaagaa ttagctgaat
     3541 ttactgcaat tgttgttact ggagattatt tagcggctaa attagtaaaa tttttaaaaa
     3601 ataagaataa acgagtgatg gaacaattat cgattattgg atttgatgat attacttttg
     3661 cagaattaat ggatcctgcg ttgacaacaa tacgactaaa tccaggtaac aagggggcga
     3721 ttgcttttca ccaactgatt ggactggcca aacaagaaga aataaaaaat caagtactac
     3781 tattagaggg agaattgatt tctcgagact ctgttcacaa aatcaaataa aaaagctctg
     3841 tgaaataagt atagttaaca ataaaatatc cgaacgatag agagaatgaa ctgtgatcta
     3901 gcagttcctc gtcgcaaatt cactagaatt agcattattt actctaaatt gttcggatat
     3961 tttttcttgt ttttaattat gattacagtg cctattttta acgaaatttg cttattttca
     4021 aaatgtatga ttatatgtta gtaaacactt tcaaatatga aaagaggagc tattatggta
     4081 ggaattaggg atgttgcaaa acgggcgggt gtgtccattg caacagtatc gcgcgtgcta
     4141 aatgaggatc cgacactttc agtaaccgat gaaaccaaac gaaagattgc agaatcggtt
     4201 aatttttatc attatgtcaa aaaaagtccc gttgcaaaaa atttaacaaa tattgcatta
     4261 ataacgacag tttctgaagt agatgagttg gaagatccct attttcgaac gattcgcaga
     4321 gggattcaag tcgaagcaga acaaagcaaa gtcaatttga agaaaattat tcgtttgtca
     4381 gaaacaccgt tggagcaaga cgatttgcta aaatgtcaag gtgtgttgat tattgggcag
     4441 gtgctatctt ctgtgattga agaagtatca gcaattaatt cgaatgtcgt agtgattgat
     4501 gaccctagta ttgaagctga agtagatgca gtttatactg atttaacaaa agcaacgaat
     4561 cagcatttag atcgattgta taaaaaagga caccgaaaca ttgcgtttat cggaggagga
     4621 cgtgttcgtt tagatagcca aggaaataaa cacgtgtcag atgatgatta tcgaaaaata
     4681 gcctatgaga cgtggatgaa acaaaaagga ttagaaaaat atagtcaaat ttatttagaa
     4741 ggctggacca cacttgacgg aatgcaggca gcagatttac ttttgaaaaa acatgctaaa
     4801 gataagttgc cgactgctat catggtagga aatgatccta ttgctgtggg ggtttatcgt
     4861 tcacttcaaa aaaatggtct acatattcca gaagatattt cgattgtgag ttttgataat
     4921 attgaagttg ctgaattttt aacacctgca ttaaatacgg tgaatgtgaa tacagaagaa
     4981 attggaaaac tagcagttcg catggttaat gaacgaataa aagaagttag aaatgtttcg
     5041 atcaaagtga ttgtttctaa taatattatt gttagagaaa gtgaaaaaaa tatcgattaa
     5101 aaaagtaaac atccaaaaaa gggtgtttac ttttttgttt actaatattt ttagtaaaaa
     5161 atctcgacaa aacattaagt aaacagttat ggtgttgtta acaaaaagaa aacgcattca
     5221 aaacaggagg aattaagatg aaacatttca aaaaaatagc tttaacaggg atagctgttt
     5281 taactgggac attactcgca gcatgtggtg ggggagatag taattctaaa gacgggcaag
     5341 taactttaag ctatgcgagt tgagatactg accaagctcc aggactaaga aaaatgttag
     5401 atgaatttga aaaacaaaat cctgatatca aagtagaaat ggagacaacg ccttgggatc
     5461 aatattgggt taaattagaa gctgcaacaa cgggaggtaa tatgccagat gtagtaacca
     5521 tgcactctag cgaatcctat aaatatatgt cacagaatgc tttgatggga cttgatgatg
     5581 ttatcaaaga aaatgatatt gacatgggaa actttactga aggaattgct gatttctata
     5641 cgcttgaaga cgaactatac gcaatcccta aagatgcttc tgtagtgggg ctatggtaca
     5701 acaaagaatt atttgataat gcaggtgtcg attatccaga tgaaacatgg acatgggaaa
     5761 cactcagaca agctgcaatt gatttaacag atgaatcaaa aggcatctat ggttttgcat
     5821 cacatattgg aacagagact ggctactggc catttattta tcaaaatggg ggagaagtat
     5881 ttgccgatga caatacaaaa tcaggtttga ataccccaga agcacaagaa gctttagctt
     5941 tttatcgaga tattgcactt gttgatcatg cttcaccaac aattacagaa ttacaagatc
     6001 ctgataagtt aagtcgtttt caatcaggta gattagcaat gatgattgaa ggaaactggt
     6061 ttgcaccggg atttttgaaa aatgactatc tagttgaaaa tgttgcttct gccgtgttac
     6121 ctaagggaaa agttaatgca acaattacaa atggacttgg ttgggctgcc agtgcgagta
     6181 caaaataccc agaagaagtg aaaaaactaa tggcattttt agctagtgag gacgccaata
     6241 aaatccaagc ggaaacgggg gcatcaatcc cagcactaaa aggctttgaa gacgagtggg
     6301 ctgcttcttc agatacaatt gatttgagtg cttttggaaa aatgttggag tatggagtcc
     6361 ctcgtccata caataaagat ggattacgag ctgaacaagc agaagttcaa attattaacc
     6421 gtattctgtc tggtgaagta actgttgaag atggaaccgc tcaaattgaa aaagaagtca
     6481 atgcgatatt gagcggaaat taaattagtt aattatacaa tatacaggcg aaaggattct
     6541 atttcgtctg tatattaatg gatgaatacc aaaaaggggg atattatgaa aaatcgaatt
     6601 tttggaaaat atcgtaaaga tcaagtgata tggggctata tttttatttt tccaacggca
     6661 ttaggattaa ttttattaaa tatatggcca gcaattcaaa cagcaatttt aagttttcaa
     6721 aaaacggtag ggttcggtga tactgaatgg gtcggattaa gaaattacca aaaaatgttt
     6781 gcagacggtg aagtttttca gtctttatta aacacattaa tttatgcagt ggtttcgata
     6841 cctagtattg ttgtattatc cttgttggtg gcagttttaa tgaatagaaa agttaaagga
     6901 ttgtcgattt atcggacaat ttattttcta ccagtcgttg ctgcaccatc cgcagtcgca
     6961 atgatttggc gctggatgtt caataatgat tatggactga ttaataacat gttggctaaa
     7021 ataggtctcg atggaccagc atggttaacg gatccatcga ttgcgattta ttctattatc
     7081 attgtaggag tttggagtgc tattggttat aacatggtgt tattactagc cggcttataa
     7141 gaaattccta aagattatta tgaagcagcg gaaattgatg gtgctagtcc aatccagcag
     7201 tttttcaaca ttacgttacc attagttaca ccaacattat tttttgtagt tgtaacaaca
     7261 gttatcaatg ctttccaagt atttgatgtt atttttatga tgattactcc taatagtacc
     7321 gccatgttta aatcacaatc attagcctat ttattctata aacattcatt tattttaaat
     7381 gacaagggat atggttcggc aatcgttatg ttccttttag tgattatatt aattattact
     7441 gcaattcaaa tgaagttgca gaaaaagtgg gtaaactatt aaggaggcta tcaaattatg
     7501 aaaaataaat ttttttcaaa tgcgccaatc catatcatgc ttattttagg tggtattgca
     7561 atggcattac cttttatttg gatgatttta acttcaggga aaacgttggt tgaatctacc
     7621 caaattccac ctacaatttt ccctgagaaa tttcagctaa gtaactatca acaagtactt
     7681 gatttattac cattcatggc tttttatatc aatacatttt taatggttgt tggacgagtg
     7741 attggctcgg ttttattttc agcaatggct gcatatgctt gtgcgcgtct aagttttcca
     7801 gggaaaaata tccttttcag cttagtactt attcaaatga tgattcccgg ttccattttt
     7861 attactccac agtatttatt agcacaaaaa ttgggtattt taaatacaat tccagcatta
     7921 atattaccag gggtagttag tgcgtttggt acgtttttat taagacaatt tttcttaggt
     7981 ttacctgatg aattggagga agcggcctat ttagaaggtg ccaatatttg gacgatcttt
     8041 ttcaaaatta tgttgccgct tgctaaatca ggattggttg cacttggaat attcacagcg
     8101 ttgtttgcat ttaaagattt aatgtggcca ttgattgtca atacttcaat tgataagatg
     8161 cctttagctc cgggattagc aaacttacaa ggacaatatg ccacgaactt cccacaatta
     8221 atggcaggtt cgttattagc aatttggcca atagttgtga tattcatcgt tttccaaaga
     8281 aaattcattg aaggaattgc tacaacaggt agtaaattat aaaactatta attagtgatt
     8341 ggagagtaag tacatgacaa aaattacatt tattggtgca ggaagtacta tttttgcaaa
     8401 aaacgtatta ggcgatgcga tgttaactcc aagtctacaa gatgcacata ttgcattgta
     8461 cgatattgat gaaaaacgac taaaagaatc aaatttaatg cttaaaaata ttaataaaaa
     8521 ttcgaatgaa aatcgtgctg atattgtttc ttattatgat cgcaaagaag cgttaagaga
     8581 ggctgatttt gttatcaatg ctattcaagt gggtggttat aaaccttcaa cagtgattga
     8641 ttttgatatt cctaaaaaat atgggttgcg acaaactatt ggtgacacca tggggattgg
     8701 tgggattttt agaaccctac ggacactacc agtaatgtta gactttgcta aagaaatgga
     8761 agaagtttgt ccaaatgctt ggttattgaa ctatacaaat ccgatggcga tgttaaccat
     8821 gggtgtttta aaagcgacga gtattaagac tgttggttta tgtcatagcg ttcaagtatg
     8881 cgtaccagaa ttgtttgagc atttaggaat agccgatcaa tatgacttaa atgactttca
     8941 atggaaaatt gcaggcatta atcatatggc attcttgttg gaaattacaa aaaatgggga
     9001 agatttctat ccaacaattc gtcagttagc tgcagaaaaa ccaaatccac atccagattc
     9061 tgtacgtttt gaattgttga aacgttttgg ttactatatt acagaatcaa gtgaacacaa
     9121 tgcagaatac catccatact ttattaaatc aaaataccca gaattgattg acgaattagg
     9181 gattccgttg gatgaatact tacgtcgttg tgaacaacaa attaatgatt gggaaagcat
     9241 gcgagaggac attgtaaata atggggagtt aacacatacg agaagccgtg aatatgcttc
     9301 atatatcatg gattctatta cgacaggaac tccgtcagtg attgcaggaa atgtcttaaa
     9361 taaaggctta atcacaaact taccgacaga tgtttgtgtg gaagtacctt gtttagtcga
     9421 taaaaatggc gtgcaaccaa cctatgtcgg tgaattgcca acacaattag ctgctttaaa
     9481 tcggacgaat atcaatgttc aagaactgac agtagaagcc gctttaacac tagataaatc
     9541 aaaaatttat caagcagcgt atttagatcc acatctatca tctgaattgt ctttaacaga
     9601 tatcaaaaat ttagtggatg atttaatcga agcacatggg gactatttac ctgaatataa
     9661 ttaaaaagaa gctgaaagag taaggaattt tcaattcctt actcttttct tagttaaatt
     9721 tagtaaaaat attgacaaaa cacttagtaa acagttacat tagtgttaac aaaaagaaaa
     9781 cgcattcaaa ttgtataagg aggagcataa aatgaagtgg tctaaaaaaa ttattttagc
     9841 ttgtatagca ctaggagcaa cgatctcttt gactgcttgt ggaaaaaatc aggaagatgc
     9901 aagcggtaag gtagaaatag agttttttaa tcaaaaaaaa gaaatgactc aaacgattca
     9961 ggagattgct aaagattttg aagcaaaaaa ccctgatatt catgtaaaag ttgtggatgt
    10021 accgaatgct ggtgaagtaa ttaaaacacg tatgcttgca ggcgatgtac cagatgtcat
    10081 taatctttat cctcaaagta tagaattgaa agaatgggcg aaagctggtt atttagagga
    10141 cttaaccgaa gaaccgtatt tagagaatat caaaaatgga tatgcacaac gttttgctat
    10201 tgaggatcgt gtatatagca taccattaac cgctaatgtc tatggttttt actataacaa
    10261 aactgctttt gaggaaatgg ggattcaagc accagaaact tgggcagaat ttgaaaaaat
    10321 agtagctgag attaaagatc aaaacaaagt accgtttgcg attgcaggag cagaaggctg
    10381 gactttaaat ggttatcacc aactagctat agcgactgct gctggtggtg aagaggaagc
    10441 gaacaatgtt tggcgtttct cagaagttaa tggaattaat gctgaaagca aagaaatgca
    10501 aaaagatttt aatcgattag atttgttaag agaaccaaaa gctttgcaaa acaactggca
    10561 aggtgccggt tataacgata cagtagttac ttttacaaaa ggtgatgcgt tgattatgcc
    10621 gaatggttca tgggcaatgc cgatgattca ttcacaaaat ccagattttg aagtaggaac
    10681 ttttcctttt ccagcagatg aagcaggtca aagtctaacg attggcgcag gagacctagc
    10741 cttatcagtt tctgcaactt ctcaacataa agaagaagcc aaacgttttg tagaatatat
    10801 gacaacacct gaagcgatgc agaaatatta tgatgtagat ggtgcaccgt gtgctgttga
    10861 gggcgttatc gagaatactc aggattcacc attaagtggt ttaactgaac ttgcttttac
    10921 tgatcgtcat ttagtttggt tagccaaaga ttggaatagt gaaaatgatt tttatacctt
    10981 aacaacaaat tatttacaca atggcaatca aaaagccatg attaacgcat taaatgcttt
    11041 ctttaatcca atgaaagctg acggaaggta ggaaaataaa atgaaaataa aagaaatttt
    11101 aaatcgttac tgggcaatca tttttgtagc aattccaatt attttgcaga tgattttttt
    11161 ctactttcca atggttcaag gtgcttttta cagtttaact aattggactg gtctgactta
    11221 taattttgat tttgtgggtt tgaacaatta taagattctt ttttctgatc cgaagtttat
    11281 caaatcgatt ggcttcactt taattgtgac gctttgcatg attgctggac aaattggttt
    11341 tggtattttg attgcgcggg cgttgaacgc aaatattaaa gggaaaacat tctttagagc
    11401 atggttcttt tttccagcgg tcttatcggg cgtggttgtt tctttagtat ttaaacaaat
    11461 ttttaactat ggtttaccaa aaattggtag tatgttaggc attgaatttt tacaaaccag
    11521 tcttttagga acaacatggg gagcgatttt tgcagtaatt tttgttttac tttggcaagg
    11581 aattgccatg ccagtcatca ttttcttagc gggttttcaa agtattccac aagaaattat
    11641 tgaagctgct agaatggatg gggcgaatga taagcaaatt ttttggaata ttgaaatcac
    11701 ctacttatta ccaagtattt caatggtatt tattatggca ttaaaaggtg gcttaacagc
    11761 atttgatcaa atttttgctt taactggtgg tggaccaagc gatgccacaa catctttggg
    11821 gttacttgtt tataattatg cttttaaaaa caatcagttt ggttatgcga atgctattgc
    11881 tttagtctta tttatcttaa ttgggattgt ttcactggca caattaaaat tatcgaaaaa
    11941 atttgaaatc taggaggttt cccaatgaaa acatcaaaag aaaaaaatat ttctaaatac
    12001 ttgcttttat tattaggggg cttcatgatt ttagttccct tagtttcaac gctattcggt
    12061 tcatttaaaa caacacccga tattatgaat aatttctttc gttttcctaa tccagcgact
    12121 ttggaaaatt tccgaagatt gttagcggat ggaattggtc attacttttg gaattcggca
    12181 atcatcacaa tcattgcagt agttgctgtg acagcaatta ttcctatggc tgcttattca
    12241 ctagcaagaa aaatgactcg tgggaaagca tacggattga tgtatttatt tttaatttta
    12301 ggaatttttg ttcctttcca agtaattatg attccgatta ccgttatgat gagtaaaatt
    12361 ggtttagcaa atatgtgggg attaatctta ctctatctca cttatgccgt accacagaca
    12421 ctatttttat atgttggttt tattaaacta aatgtgccta tcagtctgga tgaggctgct
    12481 gaaattgatg gggctagtca ctttacaact tatttcaaaa ttgttttccc aatgttaaaa
    12541 ccaatgcatg cgacgactat tattcttaat gctctatggt tttggaatga tttcatgcta
    12601 ccattattaa ttttaaatcg tgattctaat atgtggacac taccattgtt tcaatataat
    12661 tatacgggac aatattttaa cgactatggt ccaagttttg cttcctatac agtaggaatt
    12721 gtcacgatta cactagttta tcttgctttc caaagaagta ttatagctgg aatgagcaat
    12781 ggagcagtga aataaccaat aaattattct cattataaag gagttcataa acttatgatt
    12841 atatttgaca atcacacaca aacatttcat ttacaaaata aaaaaattag ctatctatta
    12901 ggaatcgaag aaaataatta tttaacgcat ctttattttg gaaaaaagat tacgcactat
    12961 tctggtgggt atcgctaccc ccgaacagat cgttccttct cacccaacaa tgcaaatgcg
    13021 caagatcgtt tattatcttt agacacatta ccattagaat ttccaggata tggacatggt
    13081 gattttagag aaccggcgca taatattaaa ttaggaaacg gtagtcgtgt aaatgatttt
    13141 cgttatgata gctacgaaat tcaaaaagga aagcccagct tagcgggatt gccagcctta
    13201 tatacggaag atgatgatga agctgaaacg ctgattattc aattgaaaga cgcgattagt
    13261 ggattgactt tacagttgtt ctacacaatt tatcaaaatc acagtgtaat tattcgttct
    13321 acgcaattag taaataatag tgatgaaaca gtggagatta accgcttagc tagtcaatca
    13381 attgattttc caaatcgtcc actcgagtta attcatttaa atggtacctg ggcaagagaa
    13441 cgtcaaatga ctagagaaaa aattcataca gggataaaag tattagatag taaacgcgga
    13501 tcaagcagcc atcaacaaaa tccgtttgtt gctttagtag atgccaaaac agatgaattt
    13561 caaggagagg catatggatt taatttagtt tatagcggta atcacgaaac ggtgattcaa
    13621 aaagatccat ttgaccaaac acgggtcatt atgggaatta attcatttaa ttttggttgg
    13681 caactaaaaa ctggcgactc atttcaaacg ccagaagtcg tgatggttta tagtaatgaa
    13741 ggtctgaata cgttatcaca gacgtatcat gaattgtata atcaccgttt aattcgtgga
    13801 aactatcgtt taaaagaacg tcccacgtta atcaacaact gggaagcaac gtattttgat
    13861 tttaacgaag aaaaaatcat gaatattgtc gatgatgcga agaacttggg cattgaaatg
    13921 tttgttttag atgatggttg gtttggcggt cgtgaaaatg acttcacttc attaggtgat
    13981 tgggttgaaa cagaaggcaa acttgcttgt ggtttggaaa atttagccaa gcaagtgcat
    14041 gataacggga tgaaatttgg gatttggttt gaaccggaaa tgatttctga agatagtgaa
    14101 ctatttcgag cacatccaga ttgggcattg ggtattccag gtcgtgaccg ctcaattagt
    14161 cgaaatcaat atgttcttga tttttcaaga caagatgttc gtgataatat ctatcaacaa
    14221 atgacggcga tttttgatcg tgtaccgatt gattatgtga agtgggatat gaatcgaaat
    14281 atgacagaag tctattctgt cttgttggac tcaacgatgc aaggtgaagt ggctcatcgt
    14341 tatatgttag ggttatatga atttttagaa aagttaacaa cgaattatcc aactatttta
    14401 tttgaaagtt gttcgggtgg aggcggtcgt tttgatgcag gtttcttgta ttacatgcca
    14461 caaacttgga cgagcgacaa taccgatgcc gtggctcgtc tgaaaattca atatggaacc
    14521 agcttagtgt atccaatttc aagtatgggt gcgcatgttt cagcagtccc aaatcatcaa
    14581 acaggaagag aaacgagttt aactattcgt ggcaatgctg cgatggctgg tgtttttggt
    14641 tatgagctag atctaacgca attaacttct gaagaaaaag cagaaattaa agaacaagtt
    14701 gccttttata aaaagcatcg ccaacttttg caatatggaa ctttttatcg cttggaaagt
    14761 ccgtttgaag gcaatgatac tgcatggatg tttgtctcaa aagaccaaac agaagccatg
    14821 gtcttttatt tccgagtatt agcagaagct gcgcatccat tagtcacatt gaaattagca
    14881 ggattagcag aagaagcaac ttatcaaatg gaagatgtaa catttgctgg cgatgaattg
    14941 atgaatctcg gtttttatat tgactcagaa ctacatggtg attatgcgac acaacgcttt
    15001 tatttgaaac agatatagta gcttgaattt acaatataag tgcaacacca aaagagactc
    15061 attccaaacg aagaaaatat gttttattta cacgcattta ctaaaaagca gcctgatttg
    15121 aattgggaaa atgaagaagt acgtgaagaa atctatgcaa tgattaacta ttggttagat
    15181 aaaggactag gcggatttag aatcgatgcg atattaaaca tcaaaaaaaa actagagtat
    15241 ggcatctttg aatctgatgg agaagatggg ttagccttca ttgggccctg gattcttaat
    15301 cagtcgggca ttgaagtgtg gttaaaagaa atgagagagc ggacatttaa accacataat
    15361 agtatgacgg tagcagaagc cgatgttcct aatgaacgtt tagatgaata tattggtgaa
    15421 gatggctatt attcgatggt ttttgatttt agttatacgg atattgatgt acctgaaact
    15481 ggtgaatggt ttaaagatag ccaatggaca tggacggata tgcgtaccaa tatttttacg
    15541 aatcaattag ttacgcaaga taaaggttgg ggcgccttat atttagaaaa ccacgatcaa
    15601 ccacgttcaa ttaataaata tattccagaa gaatggatca atgattatag taaaaaaatg
    15661 ttggcgacgc tttttatgtt actaagaggt acccctttta tttatcaagg acaagaacta
    15721 ggaatgacca acatagaaat ggcatcatta gaagattttg atgatgtagc tacgcattct
    15781 cagtataaac gggcattaga atatggattg gcaccagagc aagcattgaa agctgtcaat
    15841 aaacgaagtc gggataattc tcgcacacct atgcaatgga atacgcaaaa aaatgccaga
    15901 ttctcaactt ctgataatgt atggttaaaa gtaaatccta attatccaga actcaatgca
    15961 gaagctcagt taaccaatca acagtcggta ttcaattatt atcatcaatt aattaaatta
    16021 agaaaaaata gtgtatacaa agacgtgcta atctacggac aatttctacc agtgaaagat
    16081 aaaaatgaac atattttgct ttatgaacgc caattagaag ataaaatcgt attagttatc
    16141 ttaaacgtta cagcaacaga acaagaatat tatgtagatg aacagtacca acaagtatta
    16201 atcaataatt atgaagatgt tttattagat caaagtcgaa aattgcgttt acgaccgttt
    16261 gaaagtattg tattagctaa ttatggagga caattatgaa aattaaaaac gaagcaatgc
    16321 tcatcaccta tgcagatagt ttaggaaaaa acatgggcga attaaaacaa gtcttagaca
    16381 aacatttaca aggtgttatt ggtggtgtac atctgttgcc tttttttcca tcgacaggtg
    16441 atcgaggctt tgcgccgagt gattatacga cagttgatcc agctcttgga acatgggaag
    16501 atgtggaagc attaggtgaa gattattatt tgatgtttga ttttatgatt aatcacattt
    16561 ctcgtgaatc aaaatttttc caagatttca aaaaaaacca tgagcagtca ccatacaaag
    16621 aaatgtttat ccgtattcat gaatttttcc cagaaaatcg accaacacaa gaagatattg
    16681 atttaatcta caagcgtaaa gacaaagcgc cgtttcaaac ggtagaattt gcggatggta
    16741 cgacagaaga ggtttggaat acctttgggg aagaacaaat tgatttagat gtgaccaaag
    16801 aagttgtgaa agaatttatt cgagaaacca tcaaagatat ggcgaaccat ggctgttctt
    16861 taattcgatt agatgcgttt gcttatgcga ttaaaaaatt agataccaat gatttcttcg
    16921 tggaaccaga tatttgggaa cttttagacg aagtgcgtca agaagcagcg aaatatgacg
    16981 tcgaattatt accagaaatc catgagcatt attccattca aatgaaaatt gccaatcatg
    17041 attattatat ctatgacttc gccttgccaa tggtcactct gtattcactt tatagtggaa
    17101 aatcagaacg tttagccaat tggttgaaaa tgagtccgat gaagcagttt acaacattgg
    17161 atacgcatga tggaattggt gttgtggacg ctcgtgattt attaacagat gaagaattgg
    17221 attacacctc tgaggaattg tataaagtcg gggcgaatgt gaagaaggtc tattcaagtg
    17281 ccaattacaa taatttagat atttatcaaa ttaacagcac ctattatagt gcattaggcg
    17341 ataatgaccg tagctatctg ttagcacgtg cgattcaagt atttgcgcca gggattccac
    17401 aaatttatta cgttgggtta ttagcaggaa aaaatgatat tgaactgttg gaagcaacga
    17461 aagaagggcg taatattaat cgtcattact atgatttagc cgaaattgaa gaagaagtgc
    17521 aacggccagt gattcaacaa ttatttgcac ttttaaaatt tagaaatgaa tctgcggcgt
    17581 ttgatttgga tggaacgatt gaagtagcaa cgccatcaga atcagaaata gtgattacac
    17641 gtaaaaataa aaacggtagt gatagtgcaa cattaacggc taacttggat acgaaagaat
    17701 ttatcattga gtctaaagat ataaaaattt tcactagtgt tgcattaaaa ttttaaccta
    17761 ttccatagaa caaaaaatcc tttatactag cacttggatg acttatccaa gaccaataaa
    17821 aaggactcat acatggataa gtataaaaca aatacagcat ttaataaatg gttttctgcc
    17881 ataaaattag gaaaactttc tgtcaactcc caaaaatgta tttttgatta caattcgtat
    17941 cgtaaaaaac tgtcttttga agctgtgctc aagctctttc tctacgcagt taatgaagaa
    18001 aaagaaagtt tgcgtgattt gagtacagct cttatcgacc gatcgctcca actagaaacc
    18061 gatgtgtcat cgattagtca tacccaattg tctcgagcat ttaatgcact tgaacctaaa
    18121 gtgttagaag aaatttttca acaactgtta gaaaaagttc aacatcaaat caaaccaacc
    18181 aagcgaaatc atctgtatct gattgattcc agtacgtttt cgcttagttt aaaacgtcat
    18241 aagtgggcga ctttccgtca aacaaaatca ggtgtcaagt tacacttaaa ctattgttat
    18301 atggacgata ctacgatgta tccaactgat tttaccttaa caaatgccca tgaacatgat
    18361 ctcaatcaac taccagtatt ggtgaatcaa ccagaggcaa cttacgtgtt tgatcgtggg
    18421 tattaggact ttgaaaagat ggatcagatg cattgggatg gctatttctt cgtcactcgg
    18481 attaaaaaaa acaccaaagt tcacgtgata gatactctgg aaacatcgcc agaaacagaa
    18541 attctacgag acgagctggt tcgtttagga tctaaaacct atctaaccgc caatttccga
    18601 ctagtcactg ttcaagataa gaacggacgt gtgtttcaat ttatcaccaa tcgaatggac
    18661 gtctcttcaa aagaaatctc tgatatgtat cacgctcgtt ggcaaatcga attgtttttc
    18721 aagcacatca aacaacacat gaccattaaa accttctttt ctcaaagtga aaaaggcgtg
    18781 cagaatcaat tgattttaac gatgatttcc gctctcctca cgtttctcat caaattggag
    18841 acgaaaacgg aaaaatcagt gttccaaatc aaacgattct ttcgttattt actgtttcag
    18901 ccctttgaat gttgtctaga aaaattaatt cccacatgag aaaaaagaaa tttggctcgt
    18961 tacttttggt tttcagttga ataacagata aaaaattttc tggaaaaagt catcctctgc
    19021 gtcagcacag ttttttttga cttattttca gaggaaatag ttttcagaat attctaaaat
    19081 gttttatgca acactagtga tattttttag aattagattt ctaatgtgca ttttttgagt
    19141 attaaggagc aagtatacaa agatttataa agctgattaa atttgaataa aaatatgcag
    19201 gaacgctact atttttagta gtgttctttt ttatatttga ataaaaaatg tggtggttaa
    19261 atggtggtta taacaaaaaa tgaattaatg aaattaggtt atgggaagta tcagtctgag
    19321 agaatcatac gacaggcaaa agcaattatg gcttcaaaaa gctataccta ttacgaaaat
    19381 agaagattag gactagtacc tgttgaatct gtagaagaag ttttaggtat gaagatagag
    19441 gtagaggagg attttcagaa tcatggttaa ttttaaaaaa gataaaaatg ggaaatatca
    19501 ttttactgct agtttgggat tcgacaaacg aacagggaaa agagtacaaa aaaacgtaga
    19561 ggggttaaaa cagttaaaga agaaaaaaag cgtataccga acttgtttct aattatggaa
    19621 aagaagcaga aacttctcaa agtactatgt tgtttgagga gtttttttat aaattattcc
    19681 taccttatta tcaagggaaa gtagaagaaa gaacatataa aaatcggtta tctacaatca
    19741 aaaaaacttt tcttatttct ttaaaatgga gttaagagaa atacgtccaa ttgacattca
    19801 aaagtggcaa aataatttat tgagcaaata taaaaattct tatgtaagaa acatgtatgg
    19861 gatttttcag atgtcattag atcgagcagt tgttttggga ctacttgaaa aaaatcctgc
    19921 aaaagttatt ggaaatgtga agaaaaggaa aactacagtt gatttttgga caaaagaaga
    19981 atttacaaaa gttatttcaa ctttttatat tgatgatttg taccaacatt ttggttttat
    20041 ttgtatgtgg ttacttttta tgaccgttat gcgtttggga gaagccactg cattaacttg
    20101 gaaagatatt gattttgaaa ataaaaactt gcgtgtgaat aaaacactct attataagag
    20161 agccaaaacc tatgagtttg tagaacccga aacggcttct agtattcgta caatcgaact
    20221 agacgacaat acaattacct ttttaaaagc ttggaaggag cgtcaagttt caataggagg
    20281 catgtcgttt gtactttctt ataatggaac acctactcag aaatatacaa tccgtcatat
    20341 tatgagaaga catgcaacga tcgttggtgt tcatataatc cgcatacacg gattaaggca
    20401 tagtcatgct tctttgctta tatcacaata aaaagatgca cttcgaatta aagaaaggtt
    20461 aaaacatgct gatgtacaaa cgactttagg aacttatggt catttgtatc taaattcatt
    20521 gagagagata acaaatgatc ccacagatta tatccaaact aatttttcta aaatcaaacc
    20581 gacacctatt tacgataata aaaaataaat gataaacaaa agtaggatca caccaaaaga
    20641 aacacactag aaaaactata atacaggctt ttctagcgtg ttgtttctta tttccgccta
    20701 tttatacatt atactcataa agcatttaat gcatcgatcg tagccgcatt gtctatatgg
    20761 gtatataaag ttgttgtatt ggtacttgaa tgtcccaatt gttgggcagt taataccaat
    20821 gaatttgtct gttggtagag tctagtagct aatgtatgac gcagtttgtg agggctgact
    20881 tgaattctaa agccttttga atattttgct accatccgtt cgattgcaat accggatata
    20941 cgcttggctt ctccttggta aattgctaga aataaagctt tttcgttttc tgttacttta
    21001 tatcgttctt tccgaatagc tagataatta gctaaatatt ccattgcgaa tgctgctata
    21061 ttgacagcat ctcttttatt tccttttcta gttactacca cattattctt atctaaagat
    21121 aggtcatcta aattaatatt tataacctcg gagagtctca atccagatcc taaaatcagt
    21181 gcattgatcg ccaggtctct ttctacatct cgttgataat agatcaaagc tcgtttactc
    21241 aaagtatttt tatattcatt ggcaatataa tctagataat tttgtgtatc cttatctaga
    21301 aataattttt tctcaatggc attggcacgt gcagctaacg tagttttatc tgtgatggtt
    21361 gctacttgat ccataggatt attgtctaag tatggttttc ctagaggatt attggaactt
    21421 ttcgaaagat atttaaatag aacctttaat gccgtgatat ttctattgat agtagaagta
    21481 gatagaccta agttattatt atctttgagc ttagtttttg ttgtctcttt ttttacattt
    21541 tcttttgtgc gacgtttcaa atgagatttg tacaagttta ggtcataggc agttaactgt
    21601 cttatcgagg tgatagaagt atcaggaacg atagactcac tcagaagcca ttcataaaag
    21661 agcttataat tttttagata ttctaaagtg gttcgaggtg attgatcttt atcctcacga
    21721 tcttgaacaa aatcttttat ataatcgggc atatgaagta tgattgtatc tattttttga
    21781 tatatttctg tatttttcat gtcattcatc ctttcaataa gtaggggaga agagtatctc
    21841 tataattgga ctataccaat tatagaatgt tttgtcaatt ggtatgctct aaaatttatt
    21901 aatttgtttc aaaaaaagca tataaacagg tatacgttta ataatttaaa ataaatggta
    21961 tacataaata gggaaggaaa tagaagggag caatctaaat tttttgaatt ttcttaatta
    22021 attatataga aagaacaatc tttctataga gttagacatg agagggacta tgcttgattt
    22081 aaaatcaaca agcgtatata ctgtatatac aaagaaaaag gagggagaag actatggcaa
    22141 ttaaagaaag aaaatttagg gaagtgggga actcagtagt attaactatt tcaaaggagt
    22201 ttcttaaaga aaatgggtta aatcccggag atacggtttt tttagatgaa gaaaaacttc
    22261 gagcggcaat tacaaaaaaa caagccttat ctgatgaaat tgatttagca atatctcaag
    22321 cattaactga atatgatact acttttagag agcttgtcga taaatgagta ttcattacct
    22381 agaagccaaa gatattataa aaatgaatgt aatccaaata aaaaaatact ctcctaatga
    22441 accccttggt gtaaaggatg cgaatgcttt agaaatgtgt gtagggcaac ttcgagcctc
    22501 agcttttggt gaagaggttt atccttcgat ttatgaaaaa gcagctatcc tacttataca
    22561 attgataaag aaacatcctt ttcacaatgc aaataaacgt actgctttct tagctacttt
    22621 tgtctttttg aaaatcaatg gacagctttt agctattgat caaaaagatg ctgtaaattt
    22681 agcggtatat attgctacgt atgataagga tttcgatcaa ctaaaatatg aagtgatcaa
    22741 cactataaag acacatacgc agcccattta aggagttact gtatgtgtct ttatagggtt
    22801 attagctgct atagcgaaat aattgaagta aattacaaat agctataatt caaatccaac
    22861 tatatagaaa acgtaaattt tctatatagt tggattaaga taacgactat t
//
LOCUS       DAZAOD010000038        22818 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000038 DAZAOD010000000
VERSION     DAZAOD010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.039"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            199..3477
                     /locus_tag="ACHDPO_001474"
     CDS             199..3477
                     /locus_tag="ACHDPO_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFN3369098.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(4018..5925)
                     /locus_tag="ACHDPO_001475"
     CDS             complement(4018..5925)
                     /locus_tag="ACHDPO_001475"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFN3369099.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            6055..6930
                     /locus_tag="ACHDPO_001476"
     CDS             6055..6930
                     /locus_tag="ACHDPO_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFN3369100.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            7010..7984
                     /locus_tag="ACHDPO_001477"
     CDS             7010..7984
                     /locus_tag="ACHDPO_001477"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFN3369101.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8164..9309
                     /locus_tag="ACHDPO_001478"
     CDS             8164..9309
                     /locus_tag="ACHDPO_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFN3369102.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9446..9790
                     /locus_tag="ACHDPO_001479"
     CDS             9446..9790
                     /locus_tag="ACHDPO_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFN3369103.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            10061..11347
                     /gene="efmA"
                     /locus_tag="ACHDPO_001480"
     CDS             10061..11347
                     /gene="efmA"
                     /locus_tag="ACHDPO_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFN3369104.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11485..12084)
                     /locus_tag="ACHDPO_001481"
     CDS             complement(11485..12084)
                     /locus_tag="ACHDPO_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFN3369105.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12488..13609
                     /gene="mnmA"
                     /locus_tag="ACHDPO_001482"
     CDS             12488..13609
                     /gene="mnmA"
                     /locus_tag="ACHDPO_001482"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFN3369106.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            13855..15276
                     /gene="arcD"
                     /locus_tag="ACHDPO_001483"
     CDS             13855..15276
                     /gene="arcD"
                     /locus_tag="ACHDPO_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFN3369107.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15290..16408
                     /locus_tag="ACHDPO_001484"
     CDS             15290..16408
                     /locus_tag="ACHDPO_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFN3369108.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16468..17760)
                     /locus_tag="ACHDPO_001485"
     CDS             complement(16468..17760)
                     /locus_tag="ACHDPO_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFN3369109.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            17910..18470
                     /locus_tag="ACHDPO_001486"
     CDS             17910..18470
                     /locus_tag="ACHDPO_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3369110.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            18599..18976
                     /locus_tag="ACHDPO_001487"
     CDS             18599..18976
                     /locus_tag="ACHDPO_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFN3369111.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18909..20981
                     /locus_tag="ACHDPO_001488"
     CDS             18909..20981
                     /locus_tag="ACHDPO_001488"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFN3369112.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(21192..22139)
                     /locus_tag="ACHDPO_001489"
     CDS             complement(21192..22139)
                     /locus_tag="ACHDPO_001489"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFN3369113.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            22385..>22818
                     /locus_tag="ACHDPO_001490"
     CDS             22385..>22818
                     /locus_tag="ACHDPO_001490"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFN3369114.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
BASE COUNT         7388 a         4157 c         4819 g         6454 t
ORIGIN      
        1 ttatgctctt ttttatacgt tattttaaaa aaacttattc tttttacgtt aataaatctc
       61 tttattatca acaacttaag ttatattttt tctttttata aaatacactt attataattt
      121 tgttttttat tgacagtaaa aataaattag gtaatacttt aagtaaacgc tttctaattt
      181 gttacgggag gaatacactt gttaaaaaaa cgtataaaat acagtgcgct aatgatgaat
      241 ctccttatgc tcagtacccc ggttttaatt tctgtcgttg aagttgctgc taacgaacaa
      301 cagtctgtga acgaagaaaa tgcacacgtg aacattgaag ggatgtcaac aatggaggaa
      361 ataccaagaa ctagtgaaga tatggatacg gaagaaggaa atgatcctat gatgaaagaa
      421 tcagaaaatg aaaagacaaa aaagcaatct gaagaagcaa atgaagagtg gaaaggggtt
      481 gttttcggag aaagcacaag tgctagtagg tatgccattg aaccattaga agacggcgtg
      541 cggctctctt ccacgaataa cggcggaaaa ttccagtcaa gcggatcaga tggaatgacc
      601 tattattatc aagcaatccc caaagacatc aactttagga tgcgggcgac gatcgaaata
      661 gaatcttgga cctatacgaa tgcccaagaa ggatttgctt taatggtaag agacgcagta
      721 ccaaaaaatc atttgtttgg gcaggcattt tattcaaatt catttgccat actaggcagt
      781 cggatcgaat atgtctggga ctcggataga caagaagtgg tcaacacgag cggcagcaaa
      841 tatacgatgc gacttggatt ggggacacgg gcaatcacag gaatatcatc tgaagatccg
      901 caagctgcgc cagctcctgg gagtgtctca gtggaaacaa cacctttaga gacttcagca
      961 gggttcttgg aaaaagaaac aggttcttat aatatattcg gaaacggtca tgggaatctg
     1021 tttccggcca cgaactcgat tactaaactg gacgtagaga tgaaaaaaac gaatactggt
     1081 ttagaggcat attattacga tcctgaaaca ggagaagaaa tggcttctga catcatgtat
     1141 gactgggaaa aattatacgc ttcagatgaa tcggttattt atgcaggatt tgctgcagca
     1201 aggaatatga cgatcaaggt agaaggaatc gaagttgctt actcagatcc tgcgacagat
     1261 cctcctgggc aagaaagacc tactcgcttg attgatccga tttacactgt gacctctagt
     1321 aatcattcag gaaaccaaga tcatactatg tcctttagag caaatgctga cggattattg
     1381 acaattaaaa ataaagcaac aggagaggtg cttaagaacg caaaaaactt ggctatcact
     1441 gcgaatcggg aatttgatta tcagacaaaa ctgatggaag gaacgaacga atttactttc
     1501 agttttacgc cagataaaaa ctatccgcca gaagaatacg tagagatgac tagttatgaa
     1561 acaaaagaga ttcttcatac agtggactac cgtaaaccta aatattcgac agtttatgta
     1621 acaccagaag ggtcagatgc aggaaacgga agcagacaaa atccattatc tctgacacaa
     1681 gcattgagat acgcatatgc tgggcagaca atcgtcatgg cgcctggaac ttattccttc
     1741 gaaagaggat tgacgattcc aaaaggcgtt aacgggacaa gagaaaaccc gattcagttg
     1801 attgcagaga aaaatccaga aaacaagcgt cctgtacttg attttaaagg aactggaaat
     1861 gggatgacac tgttcagtca ctactggggt ttacgagggt ttgacattac aaatagtgca
     1921 gctatgcaaa aaggattaca gatttctgga aatcataatt tgatcgaaga gattcatgct
     1981 tatcggaatg gaaatacagg aatccaaatc agcggtagct caaatgatcc tttcgaagca
     2041 tggcccgcgc ataacttagt caagaactgt acatcttttg aaaatgccga tccaggattt
     2101 gaagatgccg atggatttgc ggccaaactg acaataggag aaggaaatgt atttgacggt
     2161 tgtatcgcgt atcataatgc agatgacggt tgggaccttt ttgctaaaaa tgaaacaggt
     2221 tcgatcggaa aagtaatcat caaaaactca gttgcttatc gaaacggctg ggtaccagga
     2281 attgagggag aaggtaacgg taatggattc aaaatgggcg gttcttcttt aacgggccct
     2341 catgaattga tcaatagttt gtctttcgaa aatcttgcga aaggaatcga ttccaatagc
     2401 ggaacagata ttatcgtcaa tagcagtaca agttttaata acggttcata taatgtggct
     2461 ctttatacct cttcagcagg aaacacagac taccatgctt ctggtatctt atctttccga
     2521 acagagaatc ttgagatgag agagcagatc cgcccattga atcaaaacga agatcaaatc
     2581 taccactcgt tgaactacta ttggaatgaa cgagagaaac aatcagaaaa tactcttgga
     2641 cataccatat caaaagattg gatcgagtct ctaaatacat gttcgaaaga aggtcagcag
     2701 cctgttacgc gctatgaaaa tggaagtatc catgttcatg gactgatgca gattaaaccg
     2761 gggaatcgtc aaacagaaaa ggaaagagtg gatggtcttc cattatctgt aggtgctatt
     2821 tttgacggag aaacctcacc gtcttcggaa tatccagagt atgcaatcgt acaagaacca
     2881 aatcagacaa aaccaaatga acaaaataat ccgattatta tacaagaagc aaatggtgtg
     2941 gcggagaatg cagaaggaaa tatcattgaa ctgaagcctt ttacagtttt tgtgtcaact
     3001 ttcacaccaa atcaaggaac gcctgtcttt gaagatatgc gttatttccc agaaaagatc
     3061 caaatcgttg aaacacagtc aagtgctcaa ttttctaatc ataccgctat tttttcagca
     3121 ccttcaaaag gagaatatac gctagaagtc acttatcgtt cggaaatatt tgatggggaa
     3181 aaatggtctg ctcatacaga atctgttacc cagcaaaaag cgatcactgt gcgagaaact
     3241 gccgatgtgc ccccgggaaa tgacaaacca gaaagagaaa atccaggaaa tgaatcacca
     3301 aatggaaaac caaatggaaa accttctcat ccggatagga cagcaaaaga aagtgaaaaa
     3361 aatggcactc aaggactccc aaaaacggga gaatttaata acccgttgct agcattagct
     3421 ggaggaattt tgttaatcgg tgtagttgtt tatgtcatga aacagcgaaa aaaataagtg
     3481 gaatttctcc ttttatgatg taaaacaatt gactgaggaa agtaaaaata gaaggaaatg
     3541 agaccaatag atgtctcact tccttctatc tttttataga tgaggttctc cttgctgctt
     3601 ttgattggct gttcttatta cttgatgcag gacagctttt tcacaatctc tccactaaac
     3661 ggtgttcaat cagctgaccc tcggtattag ctcaacaaac ggcaaaatat gaggaactat
     3721 ttttccgttt ttttctctaa tactcaggtc aggacgctga tttcacaacc tctcgataaa
     3781 cggtgttcaa aagccagttt ctcggtagta agtcaaattt atgcaaaaat gtggaaagcc
     3841 attttcacaa aatttttctt actacttgaa actaagcagc tttttcacaa cctctaatac
     3901 atggtattcc agaagtaact tcttcgaaaa ataagccgaa atgtcacaaa aatttgagaa
     3961 gcgattttcc caaattcctt cttatttctt gaagctgacc acttctggca caacctctta
     4021 ccagattcgc actctttttt ctggcgctag atacatagcg tcttgttccg tgataccaaa
     4081 tgtttcatag aattcgtcaa ggttttttgg ttgcacgttt gctcggagtt tagcaggggc
     4141 atggacatcg atttgcagta aaagttgttg gtattctttt tttgcttttg tacgccaaat
     4201 cgttgcccaa ttgacaaaga attcctcgat agaaagatct gattccgttt ttgctgcttc
     4261 caatgcacag cttagaccgc ctgcatcagc aatattttcc gaaacggtta attttccgtt
     4321 tacttttccg tcagcaaaag gcagaccatc gaattcttcg atcattgctt gtgctttgtt
     4381 ttgaaattgt gtaagatctt cttctgtcca ccagttgttc aagttgccat attcgtcaaa
     4441 taaagcgccg ttattatcaa atgcatggga aatctcatga gcgataacag ctccgattcc
     4501 accataatta gcagagcttg attgttctag actgtaaaat ggtgcttgaa ggatcgctgc
     4561 cggaaagacg atcacattcc gaaatggatg ataataagca ttgaccgtgt cagcactcat
     4621 ttcccattct gaacgatcca ctggtttgtt ccatttgctg aaacgatctt ttaatgtgag
     4681 tttgctgaaa acaagagtat ttgaaagcaa agtaccaccc tgatctgcag gtactgtttt
     4741 gaactggtcg aataatgctg ggatcttatc ggggtagcct acttggatac ctaagttatt
     4801 taattttatg acggcttttt cttttgttgc atccccaagc cagtcatttt cttctagacg
     4861 ttttttataa acggcgatca tttttttcac catttgttct acgtcttttt tagcagcttc
     4921 gccaaaatat ttttttccgt agtaatcgcc aactacttga tcgaattgtc cagaggcaag
     4981 gtaatacgct gcttttttct gaggcattgc ttcgtctgtt ccagacaata cgcgagaata
     5041 gattccgctg acttggcgga attcttctga tagataacca ctaagagaac gtactgtttt
     5101 aatgatcatc cagcttttga ataacggaaa atgagcttct gtcaggatgt cattcaaatg
     5161 atcgaagtac actggatcag ttacgatcac tttatctgga gttgtcccaa tcaaacccgt
     5221 gacaagtttt ttcaagtcca gtttatctgt gtatttaata aatgtatcaa aagattgcgg
     5281 attatacatt ttgctgtaat ctgcgttttc ttctgcactt tttacatgag gagcaatcaa
     5341 tttatcaaat tgcactgctt gttccgtgat tgcttctgcc tgactttttt ctttgccggc
     5401 aagctctaat aactgaacag ccatatcaaa gaaaacgcct attagttgtg caccgttggg
     5461 atggtctgat gcataatacg tcttatctgg aaggaataaa gaaggcggat aagcaaagaa
     5521 ggcgttcgtt tgcgcattct tcatatctgc atctacatcc agattaaatg gcaatggtaa
     5581 tgtatccaac agccattctg gaaattgctt attcaattcg tcgaaagact gcaatgattc
     5641 aactttttcg attataggtt gaagcggttg agcatgcaac tcatttcttc ggtcataatc
     5701 gtttgccagt tgataatatg caaggaaatg tttcattttt tctgaagaca ctttttctgg
     5761 atgggcaagc agatcgtctg tttctcccat caaaagttgg tcgatcccgt caactaaatc
     5821 ttggaaaccg cctgtagctg gtttatctgc agggattttt gctgtttttt gccattcttc
     5881 attgactgct tcatagaaat cttgtttcaa tcgttctttg ttcattcatc gatcgctcct
     5941 tttttgtttc gtgtgcccat tatcttacaa aatgaaggaa ttaacaaata gaacataaaa
     6001 aattgaaaat tcgaacaatc aaactgattt gtttttttca atccttcact tataatgaaa
     6061 aaaaggaggc gatcccaact gaatcaagta gtggataaac ctttatattt caaagtagat
     6121 aaaaaaatta aaaaattagc cagcactcag cagctgcagt caagaaaaag taaattgctt
     6181 tttttagctc tggtttttga agatcaaagt tatgtgatta tcgatcaatc aggacatccg
     6241 gtagaatatt ctccagcaaa atatacttat caagagggtc tttcttgtaa aaaatggaag
     6301 ctgatcaatg aagagccaat cgagttatct agatggatca acagaaaaga agatattccc
     6361 gttttgatcg aagaaaaaag gtcaggaaag gaactcgcaa attgctgggt gggattgcca
     6421 gaagaacgtt ttttgaggta taagaaatgg gctaccccct caggctatct ttgtggtact
     6481 tacgcggcag cagttctcct tgcctattat caagactatc gtaaggggtg gatgcttcca
     6541 aatgagattc gcaagaaaaa tacggctgat tcgttggttt tgacgaaggc attgcgtagc
     6601 cagatccaac cactaggact tcctacgatt ccttttcagg ttagtacagg gatttctagt
     6661 tttttaaaga agaatggcaa tcatgagcgt gcacgagcaa ctcttctagg ttcatggcag
     6721 cgagctacaa aacgtatacg tgaaggcaaa cctgtgatga ttggtatttt gaaagtactt
     6781 ggcagtacat atggcaatca ttgggtgaca gcgtacgctt attttgaaac tgaaacagga
     6841 gaacgttatt acaaagtaca cgacaactgg ggcgattatc ataaagtcat tcctgccagt
     6901 tggagtaacg gaacagtttc acttccttaa gaatttgctg aaattaacag aaaatcttgg
     6961 aaaaatatgt taaactatcg aagaatagag aagttttggg gaggactaca tgagtaataa
     7021 gtatcaggat gacacgttga agatttttag tttgaatggc aaccgtccat tagctgaaaa
     7081 aatcgcgaaa gtgttcggaa cagaattagg taaaagcgtc gtgaagcaat ttagtgatgg
     7141 cgagatttcc atcaatatcg aagaaagtat tcgaggggat catgtgtata tcgttcaatc
     7201 aacgaatgca cctgtcaatg attactatat ggaactactg atcatgatcg atgcaatgaa
     7261 gcgagcaagt gcgaaaacga tcaatgtcgt attgccttac tatgggtatg ctaggcaaga
     7321 ccgcacggcg aaacctcatg aaccgatcac tgcgaaattg atcgctaact tgatcgaaga
     7381 agcaggggca actcgagtac tgactttaga tctgcacacg gttcaagtac aaggattctt
     7441 tgatattcct gtagataatt tatttacgat gccgttgttt gctcattatt accgtcaatt
     7501 aggtctgacg ggagatgaca tcgtagttgt ttcgccaaaa aacagcggtg ttcagcgtgc
     7561 acgtagtctt tcagaatatt tgaacagcac attagccatc gtagatcatg cagatgatgc
     7621 ttcaactgag ggtggttatg tgatcggtga tgttcaagga aagacatgta tcatggtaga
     7681 tgatatcttg aacacaggag caacgcttgc acgagcagca aatgtattaa aagaaaacgg
     7741 cgcaaaagaa gtatatgcct gtgcgtcaca tggattattg tccgatcatg cgaaaagtat
     7801 tttagacaat gcaccaatca aagatatttg tatcactgat tctgttttca cagaagaaaa
     7861 tcgtcatcca gaaaacttaa caatcgttac atgttcagaa ttaatgggtg aagcggtcaa
     7921 acgcatccat gaaaatacac cgatgagtcc gttattccgt ctggaagaaa aagaattcga
     7981 ataaacaaaa aaaagaggga aagaagttgt gacagaagtg agcagcttca aggagctgcg
     8041 acaagacttt tgtcacagct ccttttttct atgcccatga aacgtcctct agacaaaaat
     8101 gagctcttct ttggtttgtt cgctatttta tgctagaatg tgcctagcaa taatttggaa
     8161 gggatgaatg aagtgaaaac tatttatctg gatcatgcgg caactacccc catgcatcca
     8221 caagtaattg aagcgatgac ggcaatcatg caagacacgt ttggaaatcc ttcaagcata
     8281 catggatttg gtcgccacgc gcatgaaaaa ttggaaacag caagacaaat cattgcagac
     8341 agtctgcaag caaaacctca cgagatcatc tttaacagtg ggggaacaga aggggataat
     8401 acagctatct tagaaacagc gttctcgcgt caaaaagaag gcagacatct aatcactaca
     8461 gctatcgaac atcctgctgt tcttaatacc atgaaatatt tagagacaaa ggggtttgac
     8521 gttacatatc tgcctgtaga tgaaaaaggg aatctgtcga tcgaagaggt caaaaaagcg
     8581 ttacgagaag atacgatctt ggtctctgtg atgtacggga acaatgaaat cggaaatttg
     8641 atgccaatca aagaaatcgg tgaactttta gcggatcatc cagcttattt ccatacagat
     8701 gcggtacaag cgtacggaaa ccaaacgatc catccagaag aattaggaat cgatttatta
     8761 agtatctctg ctcataaaat caatgggcca aaaggcgtcg gtttcttata taaacgagac
     8821 ggagtaaata tccctgcatt gcttttaggc ggggagcagg aagaaaagcg gcgtgcaggt
     8881 acagaaaatt tagcagggat ctggggtatg gcaaaagcag ttgaactgct gtcacctgaa
     8941 gaacgtgaag cacgtaacaa caaatataaa ggattccagc aattgattct tgatacatta
     9001 gaagcaaacg aaatccctta tcaagtaaat ggtgatttaa cgaataaact ccctcatgtg
     9061 ttgaatcttc gcttaattgg cgaagcaaat gatttgctac tgatgaagct tgatcttaat
     9121 ggggtcgcta tttctactgg ttcagcttgt acagcaggaa atatcgagcc ttcacacgta
     9181 ttagaagcaa tgtatggaga agatacaccg atactaaaag aatccatccg tatcagcttt
     9241 ggtttgggaa ataccgaaga cgacatccag tatttccttg atcaattagt tcgtgctgtc
     9301 aaaaaataac tagtgaagtc attcttatat gaacagatgt ctgagagaac gccttcattt
     9361 tttagggaac ttaactgaaa aacctagtaa aaatcaggat aaacttttat aataaagaga
     9421 aactaatttt atcgaggtga aaatcatggc atttgaaaca acagcaacgg tactgggcgc
     9481 accaattagc tatcgtttgc atcctgatgc aaaaagatat acattgcgcg ataatggatt
     9541 tacagaaaca aacggaggca attatcaatt gatccgacca ttagatgcca cgccgcaaag
     9601 caaagaagga ttcaaattaa aaatcactgt atcaaaagat attcaaacat tgaaaatgtc
     9661 gatcactaca gcaaatggat tgaaagcagt caatattttc aaagatccaa aacagaaaat
     9721 gagccaagat aaattttatt ttctgatgga tgggatgatt agccgtgggt tattcgaaaa
     9781 agtcgaatga tctgtggata taaaaagaca actagttttg aaacggccta ttgttagatg
     9841 actaactttg taaggacgac gcaaattagt tgtctttttt atttttaaat ttaacacatg
     9901 ttgttatttt taatattttg ctgatttatt gtttctaagt aaagaaattt aaattgaaac
     9961 gattgttatt tagggaaaaa ggtatttttt gaaaaaagaa tcccgtataa tgattgttgt
    10021 gcaaacgcta tacaaaatga aaaagaaaag agggatgttt atggaaaatg aacagtcggt
    10081 cgttttaacg aattggaaga gaaattattt gttcttttta tcgggacagt ttttgtcagg
    10141 aatcactagt atggtcgtcc aatatgcgat catctggtat ttgacaagag aaaccggttc
    10201 ggcgacaatt ttgagttttg ctactttact aggaatgatt cccatggttt tactaagccc
    10261 atttgtagga ccgctagtgg atcgctggga taaaaaagct cttttgattg tcacggatat
    10321 tattgtagcg attttcgcgc ttattttagc agtagtcgga acgatttcag aatccttccc
    10381 gatttggcta gtttttgtgt ctttgtttat gcgttcggtc gcacaaacat tccaaatgcc
    10441 aacgatccag tcgattatgc cgacaatcgt tccatcttct cacataacaa ggacgaatgg
    10501 acagttagga atggtccaat cagcgaattt catcattgcg ccagctctag gtgcggcttt
    10561 gttttcagtc gttcctgtca attaccttat tttattagat gtattggggg cagtttttgg
    10621 tgtcggctta ttgatttttg tgaagatccc aaaagtttct cctgaaatat tggaagttcc
    10681 gcttactatt tttaaagatg caaaatttgg gctgcagcaa ttgatggata ataaagggtt
    10741 atggtacata acgatcaatg gtgcatttgt gatgctgttg ttcatgccag caatcagtct
    10801 gtatccattg atgacgctag attactttgg tggttccgtt ggacaggcgg gagcagtgga
    10861 agtagtctac gcagtcggaa tgctcttagg cggtgcactg atcagtttta taggaacatg
    10921 gaaagaccga atgaaaccta ttattatagc ctacatcatt atgggcctga cgatcggtgc
    10981 aagcggattg gttccaaacg atagtcaagg gttcttgtac tttcttatct tgaatgcagg
    11041 agcaggttgt gcaacgccat atttcaatac actgctgatg gcaatgatcc agcagagtta
    11101 tgaatcgaat gttttaggtc gtgtcttagg gaacttcaac tctttgatga acctggcagg
    11161 tccaattgga ttattatttg caggaccatt agctgatcgt ttaggggtag aaaaaatgtt
    11221 cttgttttcc ggaatcggga ttttattatg cggaatcgtt ttatttttaa cgtcagctgc
    11281 ccgaaattat gataaagaat tacagaaaaa actggtaaaa gaacaccatg agcaaaaaga
    11341 cgaatagtat ggaatggagt tgtgacagaa gtcttgttac aactccattt ctgatcctaa
    11401 tgttcctgtg gcaataagcc tactcaaatg aaaaatatga gtaattatct ttatttgttt
    11461 aatacttgat atagggcagt tttttcacga cctatcgtac ttcctctttg cttcatagat
    11521 ttctttgatt tgttgctcag ataacggagt gccaaatggt agtttttcct ttaagagttc
    11581 tctttccggt gcgtctacgc ctacattgac atcgttctcg ataggtacgc tgtaatgatg
    11641 gatatgtcca tgaagattgc ggatagtgtc gttaggcccg agcaacatcg gataatgagt
    11701 caagtaatat tgttgatggt cgaatttaac gatggcacct acatcataaa aataaaattt
    11761 gggacttccg tcagtaagcc taggatcatt tttttctaaa taacggaaaa aagcgcgact
    11821 gtcatggttc cctttgatca agtggattgt tccttgcagt tgagtgacca gttccaaaat
    11881 ttctgcattt gctttttcat attgcggatg catagcaagg tcgcctagat gataaacatg
    11941 gtcggtttct tttattactg cattccagct agtgatcaac tgttggttca tttcatccac
    12001 atttgcaaag agccgcggag caaagtcgtt ttttcctaat aagcgttcat ggaaaaagtg
    12061 catatcactg ataaagtaat tcatgtatct tttgcctccc ttttttctta gagtaaacaa
    12121 aatcacttat ctgagcaact cataacatct aaaaagaaaa ggttgtaaat gagacgtgca
    12181 gctttaagcg ataagaagca attttgaaaa atagtttttc acaatttata aaattattcc
    12241 ttattgccga aaggctggcc ctttttatga gtatgccaat tttttatatc gaatgctcaa
    12301 aagatgagtg attttttggt tgactatcat gtttgtgtac tgaataggtc cagtagaaca
    12361 gtatttttac gacttgataa ttaagggatg aaattttcag aaatatgacg tataatgtaa
    12421 aatactgaaa agttgcgacc ttcaactcgt agatgtttca gaatctaatt gaaatgatgg
    12481 tgatatcatg acagacaaca gcaaaacacg cgttgtcgta gggatgagcg gcggtgtcga
    12541 ctcatctgta acagcacttt tgttaaagga acaaggatac gacgtgatcg gaatattcat
    12601 gaaaaattgg gatgacacgg acgaaaacgg tgtatgcacg gccacggaag attataagga
    12661 tgtagcgaaa gtagctgctc aaatcgggat tccttattac tctgtgaatt ttgaaaaaga
    12721 atattgggat cgtgtatttg aatatttcct agccgaatac cgcgcaggac gtacacctaa
    12781 cccagacgtg atgtgcaaca aagaaatcaa attcaaagca ttcttggatt atgcaatgga
    12841 tcttggcgcc gattatgtag ctactggaca ttatgcgcaa gtcactcgcg atgaaaacgg
    12901 cgtggtccac atgcttcgtg gagtagacaa taataaagat caaacttact tccttagcca
    12961 attatcacaa gaacagcttt caaaaacgat gttccctcta ggcggcatgg aaaaatcaga
    13021 agtacgggca attgctgaac gcgcaggcct tgcgactgct aagaaaaaag attcaacggg
    13081 aatctgcttt attggtgaaa agaacttcaa acaatttttg agcaactatc tgccagcaaa
    13141 aaaaggaaat atggtcactc ttgatggtga agtcaaagga caacatgctg gcttgatgta
    13201 ttatacgatt ggtcaacgtc aaggactagg gatcggtggc ggaggagatt cgcaagaacc
    13261 ctggtttgtt gtaggaaaag atctagcgac aaacacatta tatgtggggc aagggttcca
    13321 tcatcctgca ttgtatgcca caagcttgga tgcaagtgaa atccacttta cgacgaatga
    13381 accaatgcca aaagaattca agtgtacagc gaaattccgt tatcgtcagc aagacgttcc
    13441 tgtgacagtt cgcttattgg atgataatcg tgcagaagtc gtattcgacg aacctgtacg
    13501 tgcaatcact cctggacaag cagttgtatt ttatgatgga atggaatgtc tgggtggtgg
    13561 tttgatcgac cacgcatatc aagaaacaaa agttttacaa tacgtttaag cgatattaaa
    13621 tgaatcaaaa cagctatggc taacaaaaga aacacctttt cttttggata gcatagctgt
    13681 ttttttgcaa taaaattaat ttttattcat tttatacttg aaatacttgt gtaaaaagtt
    13741 cataatatcc aataatatga ataaagttgc tttttgttaa gcaagagcag ttgcaaaata
    13801 gaagggaatc ttttgcaagt gatttgttca attttataag tgagggtgat ggaaatggaa
    13861 aagaaatcga cgggtattag caaatgggga ctggttgctc tggttgtcag ttcgtcaatc
    13921 ggaagcggtg tgtttgggat cacaagtgat ctggctagtt ctgcagctcc agggccagcg
    13981 atcctttcat ggataatcgt tgggattggt attttagctt tggtattatc gctgaatcat
    14041 ttaggagaaa agcgtccaga tctagatggt ggtattttcg gttacgcgga agcttcattt
    14101 ggtaaattag gtggcttcat cagtggttgg ggttactggt tgtctgcgtg gctgggaaat
    14161 gttgcttttg caacgatgct gatgagcgcc atgggagaat ttttcccgat attcaaaggt
    14221 ggacaaaatg ttccttctat tttatttgca agtattttta tttggggtct gactttatta
    14281 gtaaacaatg gagttgaagg agcgagcgtc atcaatacaa tcgtgacgat ctgtaaatta
    14341 gtgccattat tcctattttt aatatttgta tttatcgcat ttaaagtgaa tatattcact
    14401 gctgattttt ggggtaacgt atctgataat ctagtgaatg gaacagggca gcaaggaacg
    14461 atctggttgc agattaaagg ttgtttgatg gttatgatgt gggtctttgt agggatcgaa
    14521 ggcgcaagtg ttttagccaa ccgcgcgaag aaacgttcag aagcccagca agcatcgatc
    14581 attggtctgc tttgtttatt gtttatctat atccttgctt cgatcttgcc atacggcgtc
    14641 ttatctcaag aagagttagc aactatttca caacctgcta tggcaaatat tttaaaagga
    14701 atcgtgggaa attggggagc agcgctgatc aatatcggct tgattatttc gatcattggt
    14761 tcttggttgt cttggacgat gctcccagca gaaacaacga tgttgatggc tcgagacggt
    14821 ctgttgccga aaggttgggg aaaaacgaat aaaaaaaatg ccccaactta ttcgttagtt
    14881 gttactgcaa tcttgactaa tctattctta ttgactttct tagttactga ttatgcctat
    14941 caatttgcct attctttatg tacagcggca attttgattt gttatctact tgtcgggatc
    15001 tatcaagtcc agttttcttt aaaagaagga atcaaaaaac aagtagtgat cggtgggatt
    15061 gctgtagttt ttgaattgat gggcatcatt ttagcaggat tttcttatgt ccttttatgt
    15121 agtattgcct atcttcctgg tttttgcttc tactggatcg cttgtcgtga aaccaaacat
    15181 caaattacgg gaaaagaaaa agtaatgatt gggctgattt gtgtggccgc actgctttca
    15241 atcgggttgc ttgctgtagg ctggatcaag atataagggg gaaagaaaca tgaaaatcgc
    15301 aaatttcggt gtagaagaat ggctaaataa atgggaaaag aaagcggtat atgatattgc
    15361 acaaagctcg atcgaagcat tgacattaga cgaactcgtt ggcttagatg ggactagcgt
    15421 aagtaaattt ttcgaaaaac gcaaaaacga accattggac tatggctgga tcgaaggatc
    15481 agatgttttc aaacaagaag tcgcttctct ttatcaaacc gtcgatccgg aaaacatctt
    15541 acaaacgaat ggagcgactg gtgctaatct tttagctcta tacgcgttag tggaagcagg
    15601 agaccatgtt gtttcgatgc ttcctactta tcagcaatta tatgacatcc ccaaatcttt
    15661 aggtgccgct gttgactttg ttcatttgaa ggaagaagaa gattggcagt ttgatttaga
    15721 acagctagaa gccttagtca aacctgaaac aaaaatcatc tgtttgaata gtgcaaacaa
    15781 tcctacaggc acattgctag atcggaaaac tttagaaaaa atcgcagaaa ttgctcgtac
    15841 agtagatgca tatgtattga tagatgaagt atatgcgcct ttaacggata aaggtgaatt
    15901 cttgtcgatc gtagatgtct atgaaaaagg tatagcaacc aattccctat ccaaaaccta
    15961 ctccattcca ggtattcgta ttggctggac agctactgga cctgagttgg cagaagtttt
    16021 tcgaaagtat cgagactaca cgatgatttg cggcggagtc ctgtcagatg atcttgctgt
    16081 acatgcattg aagaataaag aaaaaatatt ggcgcgaaac aaaaagatca ttacagagaa
    16141 ccttgtgatt ttaaaacaat gggtagccaa tgaaccgaaa gttgaacttg tcgctcccaa
    16201 ttacgtctct acttctttca ttaaattagc catcgaagaa gatgaccaga cattttgtat
    16261 caatttatta gaagaaacag gagtactatt agtaccagga agtgcctttg atttaccgaa
    16321 gcatgcccga ctaggttact gttgtaaaaa agaaaccttg gaaaagggat tattcctctt
    16381 atctgagttc ttgaaaaaac aggcctaaac aaaaacactg caaggacagt ctgtgacaac
    16441 tgttcaagca gtgtttttca tttacgctta ttgtctatga gaaggagagt gccctgaagc
    16501 tatggagact cctgaagctt tttcttctgc agtttcttgc tgatggatct cttgtgtatt
    16561 gtgtcgtaca agcaagaagt tgaccaaaac aagaagagaa gtcgaaagaa agacgccgcg
    16621 ataaccaaat gcactggaaa cactggagcc gatcataggc cctactacgt taccagttgc
    16681 ttggaaagat tggttataac tgaagatccg tccagcagct tgatgaggcg aatattttgt
    16741 gatcaatgct tggacagcag ggagcagaca agcatcagag ataccaatca aaaaacgtaa
    16801 ggcagctaat tgccaaacat tcgtgacgaa tgccattggg atataaacca gaatcgcaaa
    16861 acccaaacca atcgcaagta ttctttcact cccaatcttg tcacctaagc gaccaaatct
    16921 tggagcggct atcaaagtgg caatcccagg tatcgaagca atgattccgc tgatcaacgt
    16981 aacattccca tgtccatgca gcaattggcg aatgtacaga ctgatgattg gactaatgga
    17041 attgttggat gcttggatga tcatcgttgt gacgaacata ccgatgacga cgtgtggata
    17101 tttcaagtct ttgaaaatct gtttggcaga aaccatgttt tcttttttca ctgggacaaa
    17161 tttttcatgg acgaaaaaca gactcaacaa gaagacgaaa aataagatga tccctgtaat
    17221 gaaaaaggta gggcgatagc caaacgctga agcagagatc ccgccaagaa gcggtccaag
    17281 taatgttcct gtaacagaac cagttgctaa ggttccaaga acttgaccac ttttttcttt
    17341 tggcgtccca gttgcgacaa gggcagtggc attactgata taaccagaaa aaatcccttg
    17401 aagcagacgc aatgcgacta attgatacac actagtcacg caacccatca aagaaatgac
    17461 gattgccatt cctaatgaag cacgcaacag catcaatttt cttccttttt ggtcggctaa
    17521 ttttccccac caaggagaga taagcgtagt caccaagaaa gtagatgaaa aagtcaatcc
    17581 gctccaaaag ttcaattgtg acgtactata attacctaac gtatctatgt aaagtgacat
    17641 aaaaggcatg actaaactaa atccgatacc agccataaat gttccaaacc ataagacaaa
    17701 caagttttgt tcccaagttt ctcttttcct aaataatttt tcctttattc ttgcagccaa
    17761 ttagactcct tctttctgaa aattttcatc tacagctctt tattataaac tacaatatgt
    17821 agtttatcaa tgaaagtctc ttttttctct ttctttttcg tggtaaactg aaagagtgaa
    17881 ggatttattt tatgagagga aacatggaaa tgaaaaaaag aaatctgtct caagagaaaa
    17941 tcatcgactg ctttcgagaa ctagcagaag agatggatgt tcagcaaata acctttcagc
    18001 atttagccaa acgcttggat atcaaggctc cctcgctgta taaccatttc aaaaatattc
    18061 gtgatgtcaa aacagcgcta acagcgaaac ttctgcagga acttaatgac cagctgcgac
    18121 gggctcttgt gggaaaaagt ggtcaggaag cactgcagat ctatgcagaa acttatcgat
    18181 cctttgcttt ttcaaatcaa gcagtgtatg agttactgat cagtgtaccg cataccaatg
    18241 aagctgtttt attagatgga atccatgaaa cgaatcagat cattttgcag atatttgagg
    18301 cttttcaatt aacgaaagaa gaaaaagttc atcgaagcag ggaacttcgt agtatgatcc
    18361 acggttatct ttccttacgt tttttaggat actttacaaa agaaccaaca atcgatccag
    18421 aagacagcta tttttggatg atcaataact ttatcgctac tttgccttaa acaatcagat
    18481 tcatttgtaa caattttaag atgttcatta aatgaccctt ttataagaga aaattcttgc
    18541 aactttcttg aaaagtgact aagatgagtc tagaaaagct gaaagaagga gcacgagtat
    18601 gtatcaagta attaccatgt tcggggacaa tgagccttgg tggttttttg aagactggga
    18661 agaagatatt gaagaagaag aaacattcga gtctttcgaa gaagcacgac aagcgtacga
    18721 aaaacaatgg aacgaaatcc atcaaaatta tgaatatatc aatgcaaaaa gtaactttct
    18781 cagcgccttt tggaatgacg gagatgagcg ctggtgtgaa gagtgtgacg atgatttaca
    18841 gcaatacaag ggacttgcgt tgttgaaaaa tcatcagccc atcacagtag aaagcagaaa
    18901 ggaattttat gaaacaacta attctagcgg aaaaaccaag cgttgcgaaa gacctaagca
    18961 aggtgcttgg tgctaatcaa aagcacaaaa attattatga aggacccaag gtgatcgtta
    19021 cttgggccct tggtcattta ttaggattga aaatgccgga agatctgaat aaggaatggc
    19081 agagctggca aatggacacg ttgccaatga tccctaaaaa actaggaatc aaaccacttc
    19141 ctaaaacagg acatcaatta aaagcaatca agcagctggc tcagcgaaaa gatgtctcag
    19201 aagcagtcat tgcgacagat gccggaagag aaggggaact tgttgctcgc tggatcttag
    19261 agtatgtgca tttcaataaa ccagtgaagc ggttatggat ctcttctcaa acagataaag
    19321 caatcaaaac tggattcaag caactaagac ctgcgaaaga atatgatgca ttgtatgaat
    19381 ctgctcttgc ccgggcaaaa gcggactggc tggtaggatt gaatgtgacc agagccttaa
    19441 ctgtgaagta cgcggataat ttatcagcag gccgtgtgca gacaccgaca ctagcattag
    19501 tgagagacca agaaaagaaa atcgagcagt tccgtccaca aacgtatttc acgatcacgt
    19561 tgcaagctgg aaaagaacaa gccaaaatgc ttcaaaaaaa tcaatttgct ttaaaaacac
    19621 aagaagaagc acaaaaactt gttcaattga tcagtacaag caaaggaact gtcacagaag
    19681 tccaagaaaa attaaaaacg gaatctgcgc cattgcctta tgatttaaca gagatccaaa
    19741 gagaagccaa tcaacgctat ggctattctg caaagaaaac attaagtctt gtacaaagtt
    19801 tgtatgagac ccataagatc gttacttatc cgcgtacaga cagcaaatat ctgacaaatg
    19861 acatgaaaag tacgatgaaa gaacgattgc aagcagtcag cgactttgct cctgaggtca
    19921 agcagtattt gaaaaacgga gccatcgtcc aacagacaaa agtattccaa gacagtaaag
    19981 tgaccgatca ccatgcactt ttgccaactg aaaacagagc acgttatgaa aaattaagta
    20041 atgaagagcg aaaaatctat caaatgattg tctctcgttt tttaggactg tttgctcaac
    20101 cccataaagt cagccaaaca aaagttacgg ttgaatttgg taaagaacga ttcatttttc
    20161 ggcaaaatcg tgtcgtccaa gcaggatgga aaggcgaaac tgaaactgag acggaaacag
    20221 tcaaatggga aaaaggaatg agaatcaatc ccgatttcgc catcaaaaaa gaactatctg
    20281 caccgcctaa accattgtca gaagcaagct tgcttggtca aatggaaaaa tacagtctgg
    20341 gaaccccagc tacgcgtgca gagattatcg agaaactaat caaatctgaa ctgatggaac
    20401 gtacccctca aggactgcaa gtatctccta aaggtaagca attattagta ttggtaaatc
    20461 cctctttagt aacaccagat ttgacagaaa gctgggaaaa agaccttgaa gctattgctg
    20521 caggaaagaa acaagcagga accttcttga atggaatcga aaaagaaaca aaacgcttgg
    20581 tgaatgagat caaatcaagc aaacaagaat atcaagattt ctcgattacc caaaagaaat
    20641 gcccagaatg tggggccaat ctgcgcgaga aaaacacacg tgacggcaaa atctatgtct
    20701 gcaccaattc agattgcaac taccgcagaa gaaaagatcc aaaagtctct aatcatcgat
    20761 gcccgcaatg tcaccggaaa atggaaatca tcgaaggtaa aaacggtgct tatttccgtt
    20821 gtaaatacga tggaacgaca gaaaaattgc ttgataaaaa agagcagaag aagaaaatga
    20881 ccaaacatga agaacgacgc ttgctgaaaa aatatgcaca agcagaagaa ccagaagaaa
    20941 gcccattagc agcagcacta aaagcagcaa tgaagaagta ataagatatg aaagaggttg
    21001 tgatagaagt ggtcagcttc aagaaataag aaggaattta cgaaaattgc ttctcaaatt
    21061 tttgtgaaat ttcggcttat ttccgaagaa gctacttctg gaacaccatt tattcggaaa
    21121 aaaggactgt gacaagactt ttgtcacagt cctttttcat ttaaaaaaat gtttacttca
    21181 tttgacgtat attattggtg aggcttcaat tcatttggct tcactttttc tgtttctctt
    21241 atgatataaa caggacgctg tttcgtttct aagaagattt tcccaatata tttcccgatg
    21301 attccaagac ataacaattg gattccacca atgaacagga agatcgagac catggaaggc
    21361 catcctgatg taggatcacc aaacaacaat gcccgcaaaa taatgaacaa aattgcaata
    21421 ccagaaccga cacaagacaa agcgccgata aatgaagcaa tcgttaacgg tgcatccgag
    21481 aagttcacga taccatcaat cgagtagttg aataatttcc agaaggacca agatgtttcg
    21541 ccagccacac gttcgcggtt ttcataagaa atatattctg ttttaaatcc gacccagcta
    21601 aataatcctt ttgaaaatcg gttgtattct gttaattcta ggacggcatc caccatttga
    21661 cgagtcatca agcggaaatc acgagcgcca tcgaccattt ctgtatcgct gattttattg
    21721 atcaactggt agaatttttt cgcaaagaaa ctgcgtatcg caggctcgcc ttcacgagtc
    21781 gaacgccggg tgccgacaca atcgatatca gaagtagtga tccggttgat catctcagga
    21841 agcagttcgg gcggatcttg cagatcaaca tccatcacgg tcactaaatc tcctgtagaa
    21901 gcttgcaatc cagcgtacag agccgcttct ttcccaaaat ttctggaaaa tgagacaaag
    21961 cggacataag gataagctga ggctagcttc ttgattgctg ctaacgtacc gtcttttgat
    22021 ccgtcgtcaa taaacaaata ttcgaactca tgggcacctt tgaatttttc aacctcatca
    22081 aaaaaaagag gaacagtttt ttcttcatta aaacatggga caacaattga tactttcatc
    22141 gtttctatcc tttcaatcgt atgtttatat atggtttaca ttcaaaattt aataaacctt
    22201 aaataacacc tttaaaattt gattttacgt aaaagaacag gtattctttt tgtaaactaa
    22261 cgtatttagt ttaccatgtt tcctcggttt atcaaacttt taagaacaat ttttattagt
    22321 tggcaagtag ttttggatag agaaaaagga ggaagttcca gtctattgac taggagcaaa
    22381 caaaatgaaa atacacacac ctatcggctt tttatggtta gatgcagatg aatccggatt
    22441 gactgctgta tcttttcagc caatttcaga aagcgaatca gcgaatcagc gaattttaac
    22501 gcgcacacaa gaacagtttg aagaatattt tgcgggaaaa agaaaagaat ttgatgttcc
    22561 tttatctata aagagaggta cgccttttca gcaaaatgtc tggaaagctt tgtcgaccat
    22621 tccttatgga gaaatccgaa cgtataaaga agtagccgtt gctgttgata gtccgaaagc
    22681 tgtgcgagcg attgggcagg caaatcgaac caatccattg ccaatcgtta ttccttgtca
    22741 tcgagtgatc gggcaaaatg gaaaactgac aggatatatg ggaaacgcaa tagatggggt
    22801 tgaaatcaaa cgccaatt
//
LOCUS       DAZAOD010000039        22615 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000039 DAZAOD010000000
VERSION     DAZAOD010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.040"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            127..3654
                     /locus_tag="ACHDPO_001491"
     CDS             127..3654
                     /locus_tag="ACHDPO_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFN3369115.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3651..7373
                     /gene="addA"
                     /locus_tag="ACHDPO_001492"
     CDS             3651..7373
                     /gene="addA"
                     /locus_tag="ACHDPO_001492"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFN3369116.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7442..7783
                     /locus_tag="ACHDPO_001493"
     CDS             7442..7783
                     /locus_tag="ACHDPO_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFN3369117.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8092..9135
                     /gene="pheS"
                     /locus_tag="ACHDPO_001494"
     CDS             8092..9135
                     /gene="pheS"
                     /locus_tag="ACHDPO_001494"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFN3369118.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9140..11560
                     /gene="pheT"
                     /locus_tag="ACHDPO_001495"
     CDS             9140..11560
                     /gene="pheT"
                     /locus_tag="ACHDPO_001495"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFN3369119.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="ACHDPO_001496"
     CDS             complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="ACHDPO_001496"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFN3369120.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12994..13731
                     /locus_tag="ACHDPO_001497"
     CDS             12994..13731
                     /locus_tag="ACHDPO_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFN3369121.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13745..14560
                     /locus_tag="ACHDPO_001498"
     CDS             13745..14560
                     /locus_tag="ACHDPO_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFN3369122.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14573..15220
                     /locus_tag="ACHDPO_001499"
     CDS             14573..15220
                     /locus_tag="ACHDPO_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFN3369123.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15236..15892
                     /locus_tag="ACHDPO_001500"
     CDS             15236..15892
                     /locus_tag="ACHDPO_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFN3369124.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16054..16875
                     /gene="racE"
                     /locus_tag="ACHDPO_001501"
     CDS             16054..16875
                     /gene="racE"
                     /locus_tag="ACHDPO_001501"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFN3369125.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16878..18233
                     /gene="rph"
                     /locus_tag="ACHDPO_001502"
     CDS             16878..18233
                     /gene="rph"
                     /locus_tag="ACHDPO_001502"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFN3369126.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18234..18752
                     /locus_tag="ACHDPO_001503"
     CDS             18234..18752
                     /locus_tag="ACHDPO_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFN3369127.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18859..19359
                     /gene="cbpB"
                     /locus_tag="ACHDPO_001504"
     CDS             18859..19359
                     /gene="cbpB"
                     /locus_tag="ACHDPO_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFN3369128.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19639..20559)
                     /locus_tag="ACHDPO_001505"
     CDS             complement(19639..20559)
                     /locus_tag="ACHDPO_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFN3369129.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20685..21737
                     /locus_tag="ACHDPO_001506"
     CDS             20685..21737
                     /locus_tag="ACHDPO_001506"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFN3369130.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="ACHDPO_001507"
     CDS             complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="ACHDPO_001507"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFN3369131.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
BASE COUNT         7531 a         3948 c         4818 g         6318 t
ORIGIN      
        1 cgtatactta aaaaagtaga aatatcagaa ccttaaaagg atataatttg aagaatatag
       61 aacaaatgtt cagtattttt tgatataata aaggagcacc gtatcatgtg ttgaaggagg
      121 aaaagcatgt ctttacaatt tattcttgga aacgggaaaa aagatcaccg tcaagtcttg
      181 atcgacgaag catccgcttg gctcgaccag gatgcaagta accaagtatt tttccttgtt
      241 cccaactaca gcaaattcga acaggaacaa gaaattttag cggagatgcg aagaagaagc
      301 ggaaaaaaaa ctttcagcac aacaaacgtt caagtattta gtttttatcg tctggcttgg
      361 tatttgctgc aacagacaac tcttcttaca ggaaatgaat tatcagaatc aggatctgca
      421 atgatcttgc gacagatttt agaaaaaaat gaggaagaat taacaatctt tcgcggagaa
      481 atcaataaaa gagggtttat tcgtcaatta caagaactct acagtgaatt gcgtacagga
      541 aatattcaac cagaagacct gatgctttta tttggtgatt cacctaatgc agaagaccag
      601 caacttaaaa tgaaagactt gaagctgatt ttttcagctt atgacagcga attgactcaa
      661 cgtgcactaa caaatgaaga tgcactatct atactagcaa attatatgca gacacaagat
      721 ttcaacaacg tcaaatttat tgtcagtggt ttttctcgaa tcaatggtca agagtatcaa
      781 ttactgcagg caatgatgga aaaggggcaa ttggttgtcg atttattgct ggatcgtcct
      841 tatacagcgg atcttccaga agtacttacg ctctttcatg agactggaaa gctttatttc
      901 cgtctttttc aaagtgcaag agaacggaaa gtccctatat tagtggaccg atttgcacca
      961 gagcagactc gtccgacaga gcttcaactg ctgcaaacaa tgtgggaaga gacatctagc
     1021 caaaagaaag cggcagtaca caaaataggg ggacaagagc atctccattt gtgggaagct
     1081 gaaaatccaa ctgaagaagt ccgacaatta gctgttgaaa tcagacgact agtcagtgaa
     1141 gaaaactacc gttatcgtga tatccaagtg ctgacaaaaa atatgtcttt atatggaaat
     1201 atccttcggc cgatctttca agaaatggca attccttttt atatcgatga agaacaaatg
     1261 atggaaaatc atccgctgat cgaatggatc aacagtctgt tcgctcttga ccgctattct
     1321 tatcggctaa gtgatattat gcgttttttc aaaactgaat tatttctgtc gacggaagca
     1381 gaaaccgaac ttgatgaatg gaaacaagag cgagatgaat tcaggaaaaa actggacatc
     1441 actgaaaatg tagcacttgc ttacaattat caaggaactt attggactcg tgaaaaagac
     1501 tggcagtttg tggcgtatga ttttgaagca gaacagattg aagacgtaca gtatttggaa
     1561 gaacagtcaa atacgattag acgattattt cagaaagctg taccagtatt tttgaaaaaa
     1621 ataaagaaaa gcaaaacagg acaagaggcc gcaaatgttt tttatcaatt tttgatccaa
     1681 agtggcgtac agcaacaatt attgttttgg cgtaatcagg aagtagacag aggaaactta
     1741 gaagcggcaa gaaaccatga gcagacatgg ggagcgctga ttgatctgtt ggatgaatat
     1801 gtagtaattt atggtgaatc ggcttttgac tggtcactgt tccaagaaat cattacaagt
     1861 ggtctagaaa atctaagtta tggtaaaatc cctaccgcaa tcgaccaagt gcgaatcaat
     1921 cgtttggaat tagttcgacc aaatcaagct gccgtcactt ttgcattagg gttgaatgat
     1981 caagtgtttc cagaccgaaa agagacaaaa ggattgttgt ccagtgaaga acgagaagta
     2041 ttaaatcagg ccttgccaga tggacagttt ttattcgacc catcaaagga aagtatctct
     2101 tttgagcctt tccaagccta tcttgttttt ctttccggaa cagatcgatt atatcttagt
     2161 tatgcacaaa gctatgacac agatggttcg ctgaagatgt ctccttattt gcgtagaatc
     2221 acagaatatt tatctgttcc cgtcgagaga aaagagcatt tgacgatcga aagcgaccct
     2281 aattgttatg tagggactta cagaagcgga atcaatacag tcaataggat ttatcgatta
     2341 gctttagatg aaaaaaaacc tgtaccaaag cactggcaaa agctcaaaga attagtactg
     2401 aattcgtcat ggcgaaattt tgctttacag atttttgaaa gtcaggaaca tttaaatgtt
     2461 cctgtttcga tgccagaaaa aatggcggaa gagctttatg gaaaagagat ttatacttca
     2521 atttcacgta tggagaattt ttataattgt gaatacaaat acttcatgca atttggtttg
     2581 aaattgaaag aacgaactgt ttatggtcta actccagcag caactggtga tttttatcat
     2641 gaatcattgg atcgtttctt caagctactg ttttcaaacc aattatcctt agtgaatatg
     2701 tccgatgcgc agcgtagaga ctttactgaa aaagtgctgc aggaagtatt cggagaactt
     2761 cggtttgaga tattggatag ttctgcaaga atgaactata tccgctacca gttaggacag
     2821 acgattcaaa aagtgacatg ggctttgcaa aaacagagca aaaatacagg catgcatcct
     2881 cttcagacag agattctatt tggtcagatt gctggagcaa aaggtatcac aggtctggaa
     2941 ttaccgttga gtaatggtgg aaaactccat gttcgaggga aaatcgatcg aatcgatgta
     3001 gcttctgaac aagaagatac ttggctaagc gtcgttgatt acaaatctag cggacgttca
     3061 ttcgatgtca cagaagctta ttatggcatg gctatgcaat tattgacgta tctggacgta
     3121 gcattgatgg atgcggtacg tttgactgga aaggcggctg ttaaaccagc aggatcatat
     3181 tatttacatg ttcataatcc tgtattgacg gagacagatg atgtagagaa gaatacattg
     3241 aaaaaattta gttatgatgg cgtttttgtc gatgatcccg ctcttttaga agtactagat
     3301 cattcactgg aagcaaaaga acaatcactg atctatccag tgaaaaaaaa tgcgaaagat
     3361 gaataccaaa aaggtagttt cagtaaagac aaatttttca cggaagaaga actgcaacta
     3421 ttcatggcgc ataatcggga aaatatgcgg ttagctggag atgcgattac ttccggagaa
     3481 atcaaactaa atccagctta taaagataaa cagcggattg cctgcgaatt ttgtccattc
     3541 agaagcatct gtacgtttga tgtgatgctg aaagaaaata attaccaccg tctggagaaa
     3601 atagataagg aagaagcact gcgtagaata ttgaaaagga gtgaagaaga gtgaatcaaa
     3661 ttcctttaaa accgcaaaat gaacgattca cagatgatca gtggcaagcg atttttgatc
     3721 aaggagataa tctattagtc tctgcgtctg ccggatcagg taaaactaca gtgcttgttc
     3781 gaagagtgat tgaaaaacta aaaatgggtt ttgatatcga tgaattattg attgtgacat
     3841 ttactgaagc tgccgcaaga gaaatgaaag aaagaattca agaggcatta caagaatccg
     3901 tcaatagcga aagtgaccct gtacgtagac agcattttac taagcagtta gttttattgc
     3961 ccacagcgaa tatctcaacc ttacatgctt tttgcctgac agttattcga cgttattatt
     4021 acttaattga tattgatcca gtctttcgca tgttaacaga tgaaacagaa acgatcttga
     4081 tgaaggagga tgtgtgggac gagctgagag aagcacttta tgcagaaaat gatgaacgat
     4141 ttttccaatt aacaatgaat ttttctaatg atcgttcaga tgacggcttg acgaatctgg
     4201 tgttttctct ttatgagttt gcccgtgcca accctgaccc ccaaaaatgg ctagaacagt
     4261 taagcgataa ttatcgtttg cctgaggggc tagcgaaatc tcgattatat caaaaacaaa
     4321 tccgtccttt agttttggca gatatatacc aatgtgtaca gttatatgaa cagatgactc
     4381 agttagcaca aggtgaagga ttagaaaaaa tgcatgagca agtagctgga gaacaacagc
     4441 agatcaagaa tatctatgaa gcgttctcgc aagatcggtt agaagaagct tatgctggtt
     4501 tggaacaact aactttttca acttttaaga gcagtcggaa agcagaattg aaagaaattt
     4561 ccaatgaagt caagggcatg agggataaag caaaaaaact gattcagcag ataagtaaaa
     4621 gttattttcc tgtttcccca agccaaatgg aagaattaac ggacaaagca ctaccgttag
     4681 tcgaagaaat gacaaaagtc acgcaaagct tcatggacgg tttcagtatg cgtaaacggg
     4741 aaaaaggtgt gctggatttc aatgatctgg aacatttagc gttgcagatt ctcacagaaa
     4801 aaacgaaaga tgtatggctg ccaagtgaag cttcaaaaca ttatcgaaaa aaattcaaag
     4861 aagtaatggt agatgaatat caagacgtga accaattaca agaagccatt ttatactggc
     4921 taagagaacc cgatgataca aaaggaaata tgttcatggt tggggatgtc aaacaatcca
     4981 tctattcttt ccgtttagca gatcctagtt tatttatcgg gaaatacgag aatttctcaa
     5041 agaaagaagg cggacgtcga atcgttttgg ctgagaactt ccgctctaga aaagaagtcc
     5101 tttcttttac gaatcttatt tttgaacaac taatggatcc agcagtgggt caaatcaatt
     5161 atgacgaagc agccaaactg atccaaggat tttcagactt tccagagaat gaacagtttg
     5221 agccggaaat catgatctat gaaaaagaac aggaagaatc agagattgag attccgacgg
     5281 atgatatact ggaagacaaa acagaaggcg aactttttat gacaggacta aaaattcgtc
     5341 aattaattga ttcctccttt atgatttatg ataaaaaatc aaaaaaaagt cgtccgatag
     5401 agtacaaaga cattgttctc ttgacaccta caaagaagaa caacttaacg attttagaga
     5461 ttttcaaaac attggatatt ccattagaga tgaatgatgc tcaaaactat tttcaagcga
     5521 cagaaattcg cacgatgatc tcgctgctac aattaatcga taatccctat caagatattc
     5581 cgcttgcggc tgtattgcgc tcaccgatcg tgggtctgat tgaaccagaa ttagccagca
     5641 ttcgattagc taaccgtgca catacttact atgatgctgt gcttgcttat caagcatcaa
     5701 acgaagatga attagcagct aagctggaac attttggcaa gcaactagag cattggcgag
     5761 aacttgctcg ccgttcttcg atcactgact tgttatggga tatctattat gagacgggat
     5821 atctagagta tgtggtcggt ctgccagcag gggcacagag acaagccaat ctttatgcat
     5881 tggttgatcg tgccaaagct tacgagcaaa gttctttcag aggattatac cagttcgtgc
     5941 gtttcattga aaaaatgcaa gaaaaagata aagacttagc agaaccagtc atttcaatag
     6001 aagataatgc tgttcgcgtt atgacgatcc atgcaagtaa aggcttggaa ttcccagttg
     6061 tatttttgtt agatatgaca aaggagttca acttacaaga cttgcgcaat cggtatgctt
     6121 ttgaagaaaa acttggagca ggaattcgct atatggatcc tgaaacacga gtgttatatg
     6181 atacgttacc gtttcaagcc atcaaattgg caaagcaaaa caaattgttg tcggaagaaa
     6241 tgcgtaaatt gtatgtagga ttgactcggg cagaacaaaa gcttttcatt gtcggttcct
     6301 ataaaaataa agagcaaatg atccaaacgt ggtctgaagc agctgatcat gaggagttag
     6361 tttttgatcc tgcgctacgt ttgaagggca gaagcagctt gatgaattgg attggttacg
     6421 gattgatccg tcatcctgaa atgcagaaat acttagagga agaaatttcg acttctcttc
     6481 ttcaacattc aaatgcacag ttttctattt catggatgaa tcagcaatcg atcattgaac
     6541 aaagacagtt gcttgctgaa aaagaactgg ttaacttaga tcagcagatg aaagaagatg
     6601 aaactttatt agcagattcg ttacaaaaac gtctggcata tgaatatcct tatcaagctt
     6661 cttcacaaac cacaagttat caatctgtat ctgaaatcaa acgattattc gaagatccag
     6721 atgatacaca agaatcacgt ttgactctgg aaagcagtca gaacaaagca gcatcccgtc
     6781 aatttcgtta tacgcaagaa caactagcag aaccaaaatt tttgcaaaaa gatcggcaag
     6841 tgtcagcagc tgctgttgga actgctacgc atgctttgtt acaattactg ccattagaga
     6901 tgccaactac agagagtatc catcaaaaat tacaggaatt ggtaaggaaa cggttagtag
     6961 acgaaaaagt cgcgaaaaaa gtagatgttt cttctattat atggttcttt caaacagaac
     7021 ttggtcaaca gctgattgcc aacaaagaaa acgtaaaacg agaacaacct ttttccatgc
     7081 tgcttcctgc tgacgaagta tttcaagact atccaaatca agaagatgaa ctattaatcc
     7141 acggaatcgt cgatggatac ctagaagaaa aagatcatct caatatctat gattttaaaa
     7201 cagattttat tttacatccg gatgatccag cagaaataga tgcaatcgtc caaaaatatc
     7261 aaggacagct aagactttac caacaagcaa tgtcagaagc tttgaataag ccagtagaaa
     7321 atgttttcct aattttgctt cgagtgaaac aaattataaa cattaacaaa taattataat
     7381 tgagcaaact tgacttatgt tttgtaagga ttatgctata ctctgggaag aggtgagtat
     7441 gatggagcta acacagacag aattcgtttt atgccctaaa tttgaaaaaa cattctctat
     7501 tttaggaaaa aaatggaacg gattgattat cgatgtacta ctcgaaaacg gtccgcaacg
     7561 ctttgttgag cttgcggcaa aaatcccgat ggtcagtgat cgagtattag tcgaacgctt
     7621 gaaggaatta gaaaaagaag gaatagtcac tcgaaacttt gcctgtagcg aaaagagccg
     7681 ttcagaatat ctcttgactg aaaaaggagc agacttgcaa aaagcgatgc gtcaaataca
     7741 agtttggagc gaaaaatgga tcacagagga agaatgcggt tgattttgta aaaaaaatct
     7801 tgtaaactat agtccatacg aataagtaaa gaacgatgac gaaaaagagt agtttggcta
     7861 aaccagttca gggagatctg tcgcagactg aaagcagatc ctgtgtttga aaaatgaagt
     7921 tcactttccg agttcgtctg ataaaatcag accggcaatt gtcgttaacg aagtaagagt
     7981 gcggtgtaag tcatttatcc gcaaattagg atggtaacgc gaagacctcg ttccttaaca
     8041 ggaatgaggt ctttttgttt tgtatttgga atttaaagga ggaacaagca catgtctcta
     8101 caagcacaat tagagagctt gaaagaagca acgctcgtca aaatcacagc ggcacaagat
     8161 ttaaatgaat taaatcaaat acgtgttgaa acgttaggaa aaaaaggacc gatcacagaa
     8221 gtattacgtg ggatgaaaga tctaagtcca gaagagcgac caaaagtcgg aagtttcgca
     8281 aatgagatcc gagatctttt gacagaagag atcgagcgaa aaaaacaagt attagaagaa
     8341 gaagcgttaa atgcagcttt ggcaaaagaa acaatagacg tgacactacc tggtagaaaa
     8401 gtaaaacatg gtacacgtca tatcgtgaca caaatcatgg aagaaattga agatattttt
     8461 gtgggtatgg gctatcagat cgtagaagga tatgaagtag aatctgatca ttacaatttc
     8521 gaacggatga atctgccaaa agatcatcca gcaagggaca tgcaagatac tttctatatt
     8581 tcagacgaga tattgattcg gacacatact tcaccagtcc aagcacggac aatggaaaaa
     8641 catgatttct ctaagggtgc tctacgaatg atctcgccag ggaaagtctt ccgcagagat
     8701 acagatgatg cgacccacag tcatcagttc catcaaattg aagggctagt tgttgataaa
     8761 aacatcacaa tgggcgacct taaaggaaca ttagaagtcg taatgaaaaa aatgtttggg
     8821 gaagatcgtg aaattcgttt gcgtccaagt tatttcccat ttacggaacc atcagtagaa
     8881 gtagatgtca gctgtttcaa atgtggtggt gccggttgta acgtatgtaa atacactgga
     8941 tggatcgaaa ttttaggagc tggcatggta cacccgaatg tgttgaagat gtcaggaatc
     9001 gatccagaag aatattcagg ctttgctttc ggccttggac cagaccgcgt agctatgttg
     9061 cggtatggag tgaatgatat ccgtaatttc tatcaaaatg acttacgttt cttaagtcag
     9121 ttcaaggggg agtaagaaaa tgttagtttc atataaatgg ctcaatcgtt atgtagattt
     9181 atcgaatgta acaccaaaag aattagcgga taagatgtct gtgacaggaa tcgaagtaga
     9241 gggagtaacg gttccagaag aaggcttgaa aaaaatcgtt gtcggtgaag tcaaggaatg
     9301 cgtaccacat ccagattctg atcacctttc tatttgtcaa gtcgatattg gcgaagacga
     9361 actgtctcaa atcgtttgtg gagcgcctaa tgtgaaggtt ggaatcaaag tgattgttgc
     9421 acttcctaac tcacgtatcg ctggtaatgt aaaaatcaaa aaaggaaaaa tgcgtggcca
     9481 agtatcaaat ggcatgattt gctcattaca agaaattggc tattcagata gtgttatacc
     9541 gaaagaatac gctgaaggta tctattatat gccacaagaa gctgtaaatg gcgatccagt
     9601 ttttccttat ttggatatgg atgattcgat tattgaatta tctatcacac cgaatcgtgc
     9661 ggatgcattg tcaatgcgtg gcgtagctta tgaagttggg gcaatttatc gtcagactcc
     9721 tacattcgat gacgaaaagc tggtagaatc ctcacgtcct gctagcgata aaattcaagt
     9781 ggaagttgaa gataaagaag cagttcctgc ttatcaaatc agaatcattg aaggagtaag
     9841 aatccagcca agtcctcaat ggctgcaaaa tcttttgatg aacgaaggca ttcgtccaat
     9901 caacaatgta gtagatgtga cgaactatat tttgctttta ttcggacaac cactacatgc
     9961 atttgactac gacaaattga aatcaaaaga gatctttgtc cgccgtgcaa aagaaaatga
    10021 aacattagta acactagatg gagaatctcg ggaattgaca actgacaatc tcgtcattac
    10081 taacggcaaa gaaccagttg ctttagctgg tgtcatggga gggttagact cagagatcac
    10141 gaatgaaaca acaacagttg cactagaatc tgctttattt gatccaattt cgattcgtcg
    10201 tacagcaaaa caatttaatt tgcgtagtga atcctctgca cgttttgaaa aaggaatcaa
    10261 ccatgcgact gttggagaag ccagtgaggt tgctgcagca atgatcgttt ctcttgcggg
    10321 tggggaagtt ctacaaggcg cggtcaaagg ctcagagatc aaagcagaag acgtatcagt
    10381 gaagatttca cttgaacgca tcaatcaata tttaggaaca tctcttgtcg ttaaagaagt
    10441 aaatgagatt tttgaagcac ttggatttag ctatgaagaa aaggagtatg tttattccgt
    10501 agtagtacca ccaagacgct gggatatcca aatcgaagca gatattatcg aagaagttgc
    10561 tcgtatttat ggatacgacc agttgccatc tacacttcca agtggagaaa cggttgctgg
    10621 aagcttgtca aaagaacaag aaactactcg taaaattcgt acaatctttg aaggaagcgg
    10681 attgagcgaa gcaatcagtt atgcattgac aacagaagaa aaatcaagac agtttgttat
    10741 aaatgaaagt aatattacac gtttggactg gccaatgagc gaagaacgtt ctgtattacg
    10801 aatgaatttg atcagcggac tattagatga tatcagttat aacactgccc gaaaaaatac
    10861 agagattgct ttatatgaaa ttggtcgggt gttcttccaa gaaaatgatc cacgtacaca
    10921 tctgccgcaa gaagtaaaac atgcagcaat cgctatttct ggtatttggg aagaaaaaga
    10981 ttggcagacg aaagctcaaa atgtagactt tttcaccatc aagggtcttt tagaaaactt
    11041 atttgaacaa ctaggcatca ctgaagatgt ccattatcaa acagtgacag aaatgaagga
    11101 aatgcatcct ggaagaactg ctgcgattta ccttggcgaa aaatttattg gttttgtcgg
    11161 tcaagtgcat ccaacgatta caaaaagtta tgatattcca gaaacatatg ttgctgagtt
    11221 tgatttatct gctatagtgg aagctgctca aaaagggatc gttttcgaag cagtgacaaa
    11281 attcccagca gtcagccggg acatcgcttt gcttgtaaaa gaaactgtga caaatcagga
    11341 attaacagaa gttatccgtt ctgctgccgg aagattttta acagatatcc aattatttga
    11401 tgtctatcaa ggagaaaaca ttgaaaaagg acataaatcc atggcgtata gcctgacatt
    11461 cgtcaaccca gaagcaacat tgacagatga agaaatcaat aaagcaatgg aaaaagtcga
    11521 aaaagcgttg gtagaaaacc tagaggcaag tattcgctaa gaaggaaaat atagtaagta
    11581 acgatcaagt agcttttgaa gaccatacat ttgaaaaaaa gatgtgacac aacttcgtca
    11641 catctctttt tttgatttta aaaaaggaat agcacagaga cgagataaaa aaacaggcct
    11701 ttacagcctg cttttttaga gtaaatgaat taatggaagt aattgattcc cattgctgat
    11761 tttacttcag aaagtgtttg tgcagctact ttagcagctt cttcactacc tttacgtaag
    11821 atttccataa cagctgaagg atctttttcc aattcttctc ggcgcgcacg gatcggtgca
    11881 aattcagctt ccaatacatc aatgaggtat cgtttgatct ttacatcacc aagtccgccg
    11941 cggcggtaat gagctttcat ttcttcaatt gcttctttat ctgttccgaa tacatccaag
    12001 taggtgaaga ccatattccc ttctacttgt ccaggatctt gtacatggat gtggtttgga
    12061 tcagtataca tactcatgac ttttttctgt aagacatcgg caggatcgga gatataaata
    12121 ccgtttccta acgatttact cattttgcca tttccatcga ttccaggtaa tctacccatt
    12181 ccttttggtg ggaatacgcc ttttggttcc accaagactt caccatatgt atgattgaag
    12241 ctttgtacga tttcctgtgt ctgctctagc attggttttt gatcctcacc aacaggtaca
    12301 agattcgctt tgaatgcagt gatatctgct gcttgagaaa caggatagat aaagaatcct
    12361 gtaggcacgc tttcaccgaa ttttttttgt tcgatttctg ttttgacagt cggattgcgc
    12421 cgaacgcgtc ctacgctgac taagttcaaa taatacatgg ttaattcagc taattccgga
    12481 atttgtgatt ggataaataa agtagatttt gcaggatcta atcccacggc taaatagtct
    12541 aaagcaactt gcaagacatt tgatgaaacc ttctcaggat ttttagcatt atctgtcagt
    12601 gcttgcatgt cagcaatcat gacaaacagt tggttgtctt catctgcctg catagccact
    12661 cgggttttta gagaaccgac gtaatgccct aaatgcagct tcccagttgg tcgatctccc
    12721 gttaaaataa tatttttcaa aaaagacacc tctttacgat ttgtaagtct gagcacttaa
    12781 tatcttaccg tttttcctga aaagaaacaa cagttcctaa ggaaaaaaca aggaaagagg
    12841 ataaaataac taatagatta gaaatggaag aaatatttat gggagaataa acgttctaag
    12901 aaactttaca aattactaaa ctatcagata taatgtattt tattatacat ctttaaaaga
    12961 aatcttacta aataataatg ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg
    13021 gataaatatt atggcaagtt ccacgcatta aaaaatatca atctcgaatt cgagaaagga
    13081 gaagttgtcg ttgtcattgg tccttctggt tcaggaaaga gcacgatgct tcgctgtatc
    13141 aatggattag agacgatctc ttcaggtaag ctgctgatta atgatactga cttgcatgat
    13201 aaaaagacaa aactgacaga agtccgaaaa aacatcggca tggttttcca acatttcaat
    13261 ttgtacccaa ataaaactgt tctggaaaac atcaaattag caccaatcaa agtgttgaag
    13321 caagaccagg caactgcagt caaaaacgcg gagaaatttt tgaaaactgt caatatgtta
    13381 gataagaaag attcttatcc ttccatgtta tccgggggac aacagcaacg ggtggcaatc
    13441 gccagaggtt tagcgatgaa tcctgagatg ctgctgtttg atgaacctac ttctgctttg
    13501 gatccggaaa tgattggtga tgtattagac gttatgaaaa aattggctca tgacggtatg
    13561 tcaatgattg tcgtgacaca tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc
    13621 ttcatggctg atggagaagt attggaagac agcagaaatg tgagagactt tttcgaaaat
    13681 ccaaatgaag tccgagcaca gcaatttatc agtaaagtta tcaatcattg ataggaggaa
    13741 aaagatgcgc aggttaaaaa aaatacgcct gattttcctt ttaggcattg cttttcttgc
    13801 actagccgga tgtaaaggaa atgggttggc aaatgaagat attttagagc gaagcaaatc
    13861 taccaatgaa atcatctggg gtgtcaagta tgatactcga ttatttggaa tgatggatat
    13921 tgagagcaga actgtacaag gatttgatgt agatattgca aaagcaatca ctaaaaagat
    13981 ccttggtgac aatggaaaaa cagaatttgt tgaagtcact tctaaaactc ggattccatt
    14041 attgaaaaac ggaaatatcg atgcaattat tgcaacgatg acgatcacag atgaacgaaa
    14101 aaaacaggtt gacttttcag atgtctattt cgatgctggc caagctttgt tggtaaagaa
    14161 aggaagccaa atcaaaagtg tagatgattt gaatgcttct acaacggttc tagcagtcaa
    14221 aggttctaca tcggctgcga atatccgaca gcatgcacca gatgcaaaaa ttttagaatt
    14281 agaaaactat gcagaagcat ttactgcttt acaatctggt cagggagacg cgatgactac
    14341 ggataatgcg attttgttag ggattgcaga tgaaaatcca gagtatgagt tagttggtgg
    14401 aacgtttact aatgagcctt acgggattgc gatcaacaaa gggcaagaaa acttcttgaa
    14461 agctgttaac caagcgctag aggaaatgca tgcagatggc acatacgata aaatctatca
    14521 aaaatggttt ccaaatgaaa ctgaaggaaa agtagagtaa gggggagagg caatgagcga
    14581 attgatacaa acttatggac caatctttgt cgacgggttc aagatcacat tgttttcgag
    14641 tgtcttagca cttgtgttta gtttgattat cggaacgtta atggcaatct tccaattatc
    14701 aaagaataaa gtagtgagcg ccttagcaaa ggcatatgta gaatttttta gaaacattcc
    14761 attattaatc atcgtgatgt ttttttatgt tgtcgtaccg atttattggt ttaatctaga
    14821 tggattccaa gcaggtacga ttggattaac gatctataca tctgctttta ttgctgaaac
    14881 agtacgttca gggattcaaa ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg
    14941 ttttacctat tcagaaatca tgcgttatat tgttttaccg caagcattca aaatcgttat
    15001 cccgccatta ggcaaccaat ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt
    15061 agctggttta gatttgatgt atcaaggaga cttgatcgct agtgaaacat tcaatacctt
    15121 cgatacgtat atcatcgttg ggttatttta cttagttatc acgctaccgt tatcttactt
    15181 aatggtttat cttgagaaaa aatgggcggt tcgttcatag aaggagggga aatacatgga
    15241 ttttagcggc gctttttcat ggatgaatat ccgtttttta ttggaaggat taaaggttac
    15301 tgttgaagtt tcattgtttt cgatcatttt tagtttcttg atcggtggtc tgacaggtgt
    15361 gattcgtttt gcgaatatcc ctttcttttc caaaatcctt ggtgtagtga ttgatattat
    15421 acggaatctt ccattattat tgatcatttt cttcacttac tttgccttac ctcaaatcgg
    15481 cattcagatg aacatcttct ggtccgctgt cgcagcatta acgatttttg agtcagctat
    15541 gttgtcggaa attttccgag ctggactcaa tgctgttcca aaaggacaga tggaagcagg
    15601 attatcaacg ggactgactt atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt
    15661 taaatcaatg atcccggcaa ttgtgagcca attgatttca ctgatcaaag atacttcatt
    15721 agcagtaatc atttctttac ctgaactttc tcatcaggca cgtattattt atggacagaa
    15781 caccaattat gtgcttccga tgttcatcat catgacactt atgtacttcg tggtatgtta
    15841 cgcgctttct ctgctttccg gttacttgga aaagagacgg tacagttatt aatagatgat
    15901 tcttttagcg gttgtggcaa actaaagtca caaccgcttt tcctctttcc attcgaaaaa
    15961 aagagatttc gattgtttta agcaagtaag agcacttgaa aattcacgct aaaaagtaca
    16021 caatagggag gatagaattt attgaaaaaa aggatgatac gattgacaga taatcgccct
    16081 atcggattta ttgattcagg tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa
    16141 ttaccgaatg aaaatatttt atttgtagga gacacagcac gctgcccata tggccctaga
    16201 cccgcggaac aggtaatcca gtatacttgg gaaatgacgg attatctggt ggagcaagga
    16261 atcaagatgc tggtgatcgc ctgcaatacc gcaactgcgg tggctttaga agaaatcaaa
    16321 gctgctcttt ctattccagt catcggtgtg atccttcccg gtactagagc ggcagtaaaa
    16381 aaaacacaaa ataaacaagt tggcattatc ggtacgattg gtacggtaaa aagtcaagct
    16441 tatgaaaaag cactgaaaga gaaagtacca gaattgactg tgacaagtct tgcttgtccc
    16501 aaatttgttt cagttgtcga aagtaatgaa taccattcat cggtggcgaa aaaaattgtg
    16561 gcagaaacat tagctccttt aaccactaaa aaaatcgata cattgatttt gggatgcacc
    16621 cattatccat tattacgccc catcattcaa aatgtaatgg gagaaaatgt tcaactgatc
    16681 gattctggag cagaaacagt aggtgaagta tctatgctgt tagattattt caatttgagc
    16741 aattcaccgc aaaatggtcg gacattatgc cagttttata caactggctc tgccaaactt
    16801 ttcgaggaaa tagctgaaga ctggcttgga atcggacact taaatgtaga acatatcgaa
    16861 ttgggaggaa aataaggatg cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg
    16921 agcttcaaac aaatgttttc aaatatccag aaggatcggt agtgatccgt tttggtgata
    16981 caacagttat ttgttctgca acaatagaaa attctgttcc cccttttttg agagaaacag
    17041 gaacaggatg ggtgacagca gaatatagta tgctgcctcg agcaacgagt acgagaaatc
    17101 gtagagaaag cagcaaaggg aaactttctg gtagaacaat ggaaatccag cgtcttattg
    17161 gtcgttcctt gcgtgcagta gtagacttgg aaaaattagg agaacgtagt atcatcgtag
    17221 actgcgatgt gatccaagcg gatggcggta ctagaacagc aagtatcact ggggcatttg
    17281 tggcattgaa attagccatt gaaaaacttt taagagaaaa agaattgtca gaagatccaa
    17341 taaaagaaca tcttgctgca gttagcgtag gaatcttacc agatgggact tgcgtcacag
    17401 atttggatta ccaagaagat tccgcagcac ttgtagacat gaatcttgta atgacagaat
    17461 ctggaaaatt cgtggagatt caaggaactg gagaagaagc aacgtttgat ggtgaacagt
    17521 tgaatgaaat gctctttttt ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac
    17581 atgctttgct aacagagttt gctcaaaatg atgagcggat agaagaaaca aaaacaatca
    17641 tcattgcgac aagaaatcca ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg
    17701 gatatcatgt aaaaacatta cttgactatc ctgaattgcc agatgtggaa gaaactggca
    17761 gcacatttga agaaaatgcc cgattaaaag cagaaacgat tgcacaattg cttgatcagc
    17821 cagtcttagc agatgattca ggtttgaaag tggatgcttt aggcggtatg ccaggaatct
    17881 attctgcacg ttttgcaggg gaacaaaaaa gtgatgcggg gaataacgcc aaattattat
    17941 atgaattgac agatgtgccg gatgaaaaaa gaacagcaca attccattgt acgttagtat
    18001 tcgcggcacc caaaaaagac agccttgtag tagaagcgga atggcccggt cgagtagccc
    18061 gtataccatc tggcgaaaat ggctttgggt atgatccttt atttatccca gaaggtaaga
    18121 aacaaacagc agcagaatta tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag
    18181 caatgaaaaa attgagtgcc gagtggaaac aatggctgga aggagagaga tagatgcggt
    18241 atttagtagt aagtgataat catggagaca gagatatcct cgttgactta gtagatcgtt
    18301 atcgttctga agtggatatc tttttccatt gtggtgattc ggaattagaa gcttctgacc
    18361 cattatggga tacattccaa gtggttcaag gtaattgtga ttatggacca ggattcgaac
    18421 agaaaaaagt gatccaaact ggtcaggata cagtattcat gactcacggt catttatcga
    18481 atgtccgatt tggtttgaca cagttagcaa tcgaagctcg agctgcaact gccgatatgg
    18541 tgttttttgg tcatacccat caaataggct gtgagatgga tcagaaaatc ctgtttttga
    18601 atcctggtag catttctcag cctagaggcc cgatccaaat cccatcatat gctcttatcg
    18661 aaagtttaga tgaccaaatt tctgttcaat actataaccg tgcccatcag gcagttgaag
    18721 agttggcctt ttctttttcg agagagcgct gaataaaaaa actctaattt ttaataaaaa
    18781 taagctttat tttatgaatt ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat
    18841 agaaatggag gccatcagat gattggacct atagtaagag aaatgctgct ggaaaatcag
    18901 gaaacgtttt tgattcctgc agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc
    18961 catggtttac ttgtgttatc gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat
    19021 gatcactttg taggactagt aagtttatca gatgtggtca ataaaatgat tgacttgcaa
    19081 acaatcagca tggacccgtt agaaggacta acggttgctg atgtgacaga aacagatgtt
    19141 ccgacaattg atgaaaattg ggaactagaa gaagtactcc atttgttagt cgattcgcct
    19201 tttttaccgg ttgtcacaga agatcggatt ttcaaaggaa tcattacaag aaaagagctg
    19261 cttaaagccg taaacttcat ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa
    19321 atcgaagaat taaaagaaca aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata
    19381 atcaaaaaat aagtagaaaa aacagcgtac cagttttgac tttatcttga aaaagaggct
    19441 gggacaaaag cgtttaactc caagaaataa gaaggaattc acgaaaattg cttttcaaat
    19501 ttttgtgaat ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt
    19561 ttagagcgtg ggacaaaagt gttctttact tttgtcccac gctcttttta gtgagattcg
    19621 ttgcatcgtt tgtccaaatt attttccgac agcaattgga ctgttcggaa tcgtgaaacc
    19681 agaagctgtc aattctttga cataggagct caagaactct tcttttaagg catattgttt
    19741 tccgttcaat gcgtagcaga ccgtacgaat cgcaaaattg ctgtttccaa gatccactaa
    19801 tccaaagata gaaggttcag tttggagctc ttcttggtat ttttcagcta atgtacgatt
    19861 tactcgatca atgatctcat agattttgtc atatccttct tcaggaacaa tccgaatatc
    19921 taaaagtact tgcatatttg cacgagagag attgctgatc gtggtgatgt ttcgattcgg
    19981 gatgaaatgg acagtaccat ccgttgcttt cagctgaagg gtacggatac caacagatac
    20041 gacggttcct tcaatcgtta agtttgctag cttgatgtag tccccaacat ccatctgttg
    20101 ttccatgata ataaaaaatc cggtaataac atcactcatg aacccttggg caccaagacc
    20161 gattgccaca cctgcaattc cggcaccagc caaaagtgat ccgatcggca caccgatagc
    20221 agataaaatt gcatagataa aaaagaaacc aagggtataa tgaaaaatag tatttaaaag
    20281 actatgtaaa gtctttaagc ggctctcgtt tagaatggct tttttagaat actgattaaa
    20341 agacttatca atcagatatt ttcccacacg gtgaagaatc caaaaaagga cgatcaaaaa
    20401 aatcagatat aaactttttt ggataaaggc agccaaaatg gcgtcccaat caatcccgtc
    20461 ccaaaaccgc tgaaacgcat ttactttgct gacagcttga tctgtcaatg tctcgccaga
    20521 agagtctgtc gtaccggcag ttgctaataa tgaaaacata aaatcctctt ttctaaaatt
    20581 tgattctttc tgtattgtac caagaagttt tcaaaaaagg aaatagcaaa aataactata
    20641 atgaaggaaa aaagctgaaa ataaaatgac aaataatatg gataatgata aaatgtggag
    20701 aaaataacga aggtggtaag tatatgcaaa tcgattggaa caatctaggt ttttcttata
    20761 tcaaaactcc ttggcgtttt attgccaaat ggaaagacgg acaatgggaa gaaggagaat
    20821 tgacagaaga taattacctg acgattcatg aaggctctcc agcgcttcat tatggtcagc
    20881 aatgttttga aggtctaaaa gcttatcgtc gaaaagacgg caaggtcaat ctctttcgac
    20941 ctgaacaaaa tagtcgacgg atgaatcaaa gtgctagacg attgctgatg ccaatggtcc
    21001 ctgaaaagat gttcgttgat gctgtcaagc aagtggtaaa agcaaatgaa gattttgtgc
    21061 cgccctatgg aacaggcgct acattatact tgcgcccttt actgattggg gtcggtgaaa
    21121 acattggtgt ccatccagct ccagaatatt tatttgtcgt cttctgtacg ccagtaggag
    21181 cgtatttcaa aggtggacta aaaccaacga attttattgt atctgattac gatcgtgctg
    21241 ctcctaaggg gactggtgca gcaaaagtcg gcggaaatta cgcagcgagt ttacttccag
    21301 gaacagaagc aaaagaactg gattactcag attgtgttta tcttgatcca gccacacata
    21361 cgaaaatcga agaagtaggt gcagcaaatt tctttggaat tacaaaagac ggaaaattca
    21421 tcactccgca atcgccctct atcttaccaa gtatcacgaa atattccttg ttgcagttag
    21481 ctgaagaacg actaggactg caagcaattg aaggagatat tttcattgat gatctagatc
    21541 aatttgcaga agctggtgca tgtggtacag cggctgttat ttctccaatc ggtgggattt
    21601 atcacaataa caatcttcat gtattttata gtgaaacgga agtaggacca gtaacaaaac
    21661 ggttgtatga tgaattgaca ggtattcaat ttggagacat agaagcacca gaaggctgga
    21721 ttgaagtcgt ggaataattt caaagtaatg agttgaaaaa aacgtaaaaa gaaaaaatca
    21781 ggaagagact ttaaaaagtt ttttcctgat ttttatatgt tttactttaa agaatgcaac
    21841 aaaagtttat gaaagatgga cacctttgtc aacgtagata atatcaccga tgattccgct
    21901 ggaaagtggg ctgattaaga aagcacaagc attaccgact tcttcgatcg tcacaccttg
    21961 ctgatcaggc gtacgagatt cagataactg gatcagtttt tgatagtctt taacacctgt
    22021 gacagctaat gttttgattg ccccagctga gattccattg acccgaattc ctttaggcga
    22081 gaactcagct gccaaataac ggatagcagc ttcaagagaa gctttcgcaa tacccatcat
    22141 gttataattc gggattgcgc gttctgaacc tagataagtc atgctaacga tcccgctgtt
    22201 tggtgcaaga aacggttgtg cgtattttga tacagcaatt aaagagtagc tgctgatatc
    22261 ttgagctaat tgatagccgt ctctggaaat atcagacaca tttccggaca attcttcttt
    22321 gttggcgtaa gcaactgcat ggacaaggcc gtggatctcc ccagcatatt caccgatggc
    22381 attcattgct ttttcgatgc tttcgtcgct agaaacatca cattctacag tgaatgcttc
    22441 ttcgccgacc aatttgacta atgatttttt cattcgttca ttttggtaag tatagataat
    22501 ttctgcccct tgtttcaaca ttgcttcagc acaaccccaa gcaatgcttt ttttgttagc
    22561 gacgcccata atgacgattt tttttccttc tagaaatgac ataatgactc tcctt
//
LOCUS       DAZAOD010000040        22365 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000040 DAZAOD010000000
VERSION     DAZAOD010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.041"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(2..454)
                     /locus_tag="ACHDPO_001508"
     CDS             complement(2..454)
                     /locus_tag="ACHDPO_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFN3369132.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(467..877)
                     /locus_tag="ACHDPO_001509"
     CDS             complement(467..877)
                     /locus_tag="ACHDPO_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3369133.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1152..1364
                     /locus_tag="ACHDPO_001510"
     CDS             1152..1364
                     /locus_tag="ACHDPO_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HFN3369134.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1367..1579
                     /locus_tag="ACHDPO_001511"
     CDS             1367..1579
                     /locus_tag="ACHDPO_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369135.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1719..1874
                     /locus_tag="ACHDPO_001512"
     CDS             1719..1874
                     /locus_tag="ACHDPO_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369136.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(1871..2095)
                     /locus_tag="ACHDPO_001513"
     CDS             complement(1871..2095)
                     /locus_tag="ACHDPO_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFN3369137.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2173..2361
                     /locus_tag="ACHDPO_001514"
     CDS             2173..2361
                     /locus_tag="ACHDPO_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369138.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2500..2628
                     /locus_tag="ACHDPO_001515"
     CDS             2500..2628
                     /locus_tag="ACHDPO_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369139.1"
                     /translation="MAREEALKIGKVIADNRWGNSRPIILSKQHIEKQKAWQQIKK"
     gene            2687..3022
                     /locus_tag="ACHDPO_001516"
     CDS             2687..3022
                     /locus_tag="ACHDPO_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369140.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3255..4196
                     /locus_tag="ACHDPO_001517"
     CDS             3255..4196
                     /locus_tag="ACHDPO_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda-exonuclease family protein"
                     /protein_id="HFN3369141.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4198..5088
                     /locus_tag="ACHDPO_001518"
     CDS             4198..5088
                     /locus_tag="ACHDPO_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFN3369142.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5131..5931
                     /locus_tag="ACHDPO_001519"
     CDS             5131..5931
                     /locus_tag="ACHDPO_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFN3369143.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            5946..6797
                     /locus_tag="ACHDPO_001520"
     CDS             5946..6797
                     /locus_tag="ACHDPO_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3369144.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            6998..7459
                     /locus_tag="ACHDPO_001521"
     CDS             6998..7459
                     /locus_tag="ACHDPO_001521"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFN3369145.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7485..7937
                     /locus_tag="ACHDPO_001522"
     CDS             7485..7937
                     /locus_tag="ACHDPO_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369146.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8043..8237
                     /locus_tag="ACHDPO_001523"
     CDS             8043..8237
                     /locus_tag="ACHDPO_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369147.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8268..8654
                     /locus_tag="ACHDPO_001524"
     CDS             8268..8654
                     /locus_tag="ACHDPO_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369148.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            8651..8854
                     /locus_tag="ACHDPO_001525"
     CDS             8651..8854
                     /locus_tag="ACHDPO_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HFN3369149.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            8851..9147
                     /locus_tag="ACHDPO_001526"
     CDS             8851..9147
                     /locus_tag="ACHDPO_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369150.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            9223..9639
                     /locus_tag="ACHDPO_001527"
     CDS             9223..9639
                     /locus_tag="ACHDPO_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFN3369151.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            9900..10037
                     /locus_tag="ACHDPO_001528"
     CDS             9900..10037
                     /locus_tag="ACHDPO_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369152.1"
                     /translation="MDKEIKVTVKLDLTELKELLNKASDQVEQLQETLDEIANFKIQV
                     S"
     gene            10447..10677
                     /locus_tag="ACHDPO_001529"
     CDS             10447..10677
                     /locus_tag="ACHDPO_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369153.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            10836..11669
                     /gene="terS"
                     /locus_tag="ACHDPO_001530"
     CDS             10836..11669
                     /gene="terS"
                     /locus_tag="ACHDPO_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFN3369154.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11662..13077
                     /locus_tag="ACHDPO_001531"
     CDS             11662..13077
                     /locus_tag="ACHDPO_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HFN3369155.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13089..14618
                     /locus_tag="ACHDPO_001532"
     CDS             13089..14618
                     /locus_tag="ACHDPO_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFN3369156.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14536..15588
                     /locus_tag="ACHDPO_001533"
     CDS             14536..15588
                     /locus_tag="ACHDPO_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFN3369157.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15590..15907
                     /locus_tag="ACHDPO_001534"
     CDS             15590..15907
                     /locus_tag="ACHDPO_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369158.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16034..16657
                     /locus_tag="ACHDPO_001535"
     CDS             16034..16657
                     /locus_tag="ACHDPO_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFN3369159.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16672..17562
                     /locus_tag="ACHDPO_001536"
     CDS             16672..17562
                     /locus_tag="ACHDPO_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 family protein"
                     /protein_id="HFN3369160.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17585..17800
                     /locus_tag="ACHDPO_001537"
     CDS             17585..17800
                     /locus_tag="ACHDPO_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369161.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17812..18153
                     /locus_tag="ACHDPO_001538"
     CDS             17812..18153
                     /locus_tag="ACHDPO_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369162.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18153..18524
                     /locus_tag="ACHDPO_001539"
     CDS             18153..18524
                     /locus_tag="ACHDPO_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369163.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18517..18912
                     /locus_tag="ACHDPO_001540"
     CDS             18517..18912
                     /locus_tag="ACHDPO_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFN3369164.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            18914..19291
                     /locus_tag="ACHDPO_001541"
     CDS             18914..19291
                     /locus_tag="ACHDPO_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFN3369165.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19292..19900
                     /locus_tag="ACHDPO_001542"
     CDS             19292..19900
                     /locus_tag="ACHDPO_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFN3369166.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            19900..20241
                     /locus_tag="ACHDPO_001543"
     CDS             19900..20241
                     /locus_tag="ACHDPO_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369167.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20483..>22365
                     /locus_tag="ACHDPO_001544"
     CDS             20483..>22365
                     /locus_tag="ACHDPO_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFN3369168.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTG"
BASE COUNT         8095 a         3263 c         4631 g         6376 t
ORIGIN      
        1 tttaatgttg taatactaaa tgttcaagat tatgaggaag ccctaaatat tcaataattt
       61 ggaactgact catatcagat aaatcttgtt catctattgt tctagttaac atttcaattg
      121 caaacatatt agcttcagct tctataccat aaatcataca actaaggttg tttgctctaa
      181 aagctgctgt gcaaatacct ttatggagtc taacgtgggc tatttcatgc cataatacaa
      241 atcttttcat agaaggtgat aggttttgat taattaatat cacataacat cttttattgt
      301 gtatcgtttg tcctaatgtt ttattcccta aatcagtttc aattaaatct atatcagaat
      361 atttgattat tttatatgga ttaatcgcat cagatccaaa ctctacaaat aatttttcta
      421 tttcttctaa tatccagtat ttgtttaaat gcataccaaa gcccacctat tgacgatatt
      481 ttttaggagt gaattttttc tttgctttaa ctttggttaa ggcaagtgca agttgaatgg
      541 catcgtataa tttttcctta tcttcatcgt ctaaaggttc accataataa tttgtttcag
      601 catctgaatt caagccttca agtaattttt cagcttgtaa agcaatatct tgtttatctt
      661 tttctgttaa atcataataa tggcgtttat cagtacgtcc taaaagataa tcagttgata
      721 cattaaagta atctgcaact ttttgtattt tatctccaga tggagtactt ttattccatc
      781 tagacatgct tccatttccg aaatttaact ttctttcaag ttctgccaac gtcattgaac
      841 gttcttttaa taagattttt atacggtcta atagcatagg atatgcattc ctttcaaaat
      901 accgacaaaa aaagtatttt tctgcaaatt atctatttac aaatagagaa tttgcagtta
      961 tactagtttt gtaagcaaga tatttacggc atacaaagac taaaagcaat aaactaatag
     1021 tctccccaga catcagtaag ctcgcttttt gtgcgctgta ttttgtatgc ttacataata
     1081 gcatatttgc agtttttgtc aaacttatta gacaaaaata ttagaaaata ttcgataagg
     1141 gggtatgaag catgacttta aaacagcaag tattaattgc tttagtaaag aaaggttgga
     1201 gtcaaagaga gttagctcga cgaatgggta tatcaattac ttatttacga gatatcttca
     1261 tcgaaaaaag aaaacctaag gaacgtttaa aacaaatcga agaacttttg gatatcaagt
     1321 tagaagtaga ttctaatgat cagccatcag aacaggaggc gtaaaaatgg tacaacgttt
     1381 gagcaaagcg gagtttaaag agaaatataa gtattctgaa agtacttatc aaagaagaat
     1441 gaaggaattt aaaaaatcac gttttagtga ggggtataac gcagttactt ccaaagaaat
     1501 aacaattgat gtcgatttat atgaacagtt tagaacatgg cgttctaaaa atcgatttag
     1561 agttagagct gtttgttaat agctaaaaaa tctaaattca ccacttctga aaagaggagt
     1621 tgctgctctc ctttcaagtt tgccaaagtc cacgtttttt cattttggca actcctcttc
     1681 ttggaggtgg tgacggcgag agacgaagga gggatgacat gaaggaagaa tcaaaaatag
     1741 ggattttgaa tgagaacaat tacacaagat taattattga aacagaagaa gggaaaaaag
     1801 tagcagaagt tacattgacc gatgcaactc ctgctgacgg ttatcgtatt cgattaactc
     1861 ctaaatatga ttaacctttt ggtgggtgtg gatcgtttcc gtgactatca cggctttgaa
     1921 tttttccatc tctgccatga ataaatagct cagatccttg atttttagaa atctctctag
     1981 cgatttttac tgcttctgat tttgtattag tatgtgcagt cgctttagaa tttccagcac
     2041 ctttgacatt ccaaccacca ttggaattag gtacaacatg ttgatttttt cccatagttt
     2101 tcacctccat ttctatagaa atattttatc aaatagaaat ggagaaattc aataaacgaa
     2161 aggagaagtg atatggcata taccttgcaa caagaacatc aaattctcgg tttgattaaa
     2221 caacgcagga aacaattaca agatgaccgt gcagcgctta gaaaagccga tgagctatca
     2281 gataggcaag ctgaactaat tgcttctgaa cttgaggatt tgagaatgct agaaataaaa
     2341 aatagggaga ttagattatg aagaagacag acacactttt tataggattc attttggggt
     2401 tattagtgat tgtagcgcac caaagtatta tcgggggaag cttgttcgca gcattgatgg
     2461 ttttaatcaa tctgcttgat tcaaaagaaa ggagcaacta tggcacgaga agaagcgcta
     2521 aaaatcggta aagtgattgc tgataatcgg tggggaaata gccgccctat tattttaagc
     2581 aagcaacata tcgaaaagca aaaagcatgg caacaaataa aaaagtgact ctgccagcca
     2641 gcaaagagtc acatacaaat ttataaaact aggagaatta tatcacatga ataagaaaat
     2701 tgaaaatctt atcgaagaat tgaaacgtga atgccaaaag caaggtgttt ctattatttg
     2761 tacagcccaa aaagaagggg aacttaaaag tctcgtttat ggtgagacaa cagaaatttt
     2821 actttgtctt gctatgcaag aagaacattt agatgaaaat ctcccattgt cagcacatat
     2881 tatgcgtaga attgctgtgg atgcttacga acaagcgaaa aatgaagaag aaaatcaacc
     2941 ttcaaatcat acttttgtta ttaataacaa ggaagattta gctgatgtga tgactcgtat
     3001 tctcaagggg gaatttcaat gatgaatgaa aaaacaattg atctactcat tattttattt
     3061 ttcacgttag tgattgtagc gaaaagttat gtaatctttg gcttgttatt cgcaattacc
     3121 atgcttgtgc tttgcgtgtt agcaagcaga aaagaggtta aacatgaacg agttagcaaa
     3181 tcttgacaac tatttaactg atcctgatta tgctaaacca ccatatgaag caccaattga
     3241 tgaggaggat gaagatgagt aaatctacct tagaaatgag ccatcaagaa tggcttgaag
     3301 accgtaagaa aggcatcgga ggttcggatg ttggaacaat tttaggattg aataaatgga
     3361 aatctcctta tcaactatgg ctagaaaaaa caggacaagt agtacttgaa gaatcaggaa
     3421 gtgagcccgc ttattggggt aatgttttag aagaagtggt tgctaaagag tttcaggaac
     3481 gtacaggcaa aaaagtacgc agaagaaacc aagtatttga acatccatta catccatttt
     3541 taagagcaaa tattgatcgg gaagtagtgg gagaaaatgc cattctggaa tgcaaaacag
     3601 ctaatcaatt tctcggtaaa gaatgggaag gcgaagaggt accgcttagc tatctctgtc
     3661 aagttcaaca ttacatgaac gttctaaaca aagactattg ttacatcgct gtcttaatcg
     3721 gtggtcaaaa atttatctgg aagcggattg aacgagatca agagctgatc gatacaatca
     3781 ctgaacaatt agtagagttt tgggaaacaa acgttcttgg aggtatcgag ccaattattg
     3841 atggtagtca agcgacagct gatttcttga aagagaagta tgcagatgtt gaagacgttc
     3901 aaacgacgtt accaattcat ttcgatgaac tagttgaaca gaaaaacgaa ctcaaacgga
     3961 ctaagaaaga aattgaatca gctatccgtc aagtagacaa cgagattatc agcgagctag
     4021 gtaaacgtga agccagtatc ggtatcactc aaaaaaacat catcagttgg aaatttgtcc
     4081 gtacgagacg tatgaactcg aagaaactag cagagaaata tccagatgtc gcaaatgatg
     4141 aagagattta taacgttact gaatcaagaa ggctaaccga aagggagatc aaataatatg
     4201 gcaacaaatg aatcgttaaa aaatcaattg gcagcaaagc cacagaaaca agttgcacca
     4261 ggtcaattag gacttaaagc tttgatgaat acaccaacaa tgagaaagaa gttcgaagag
     4321 gtgcttcatg acaatgctaa tgcttttatg tcgaatgtta tgactcttgt atctaatgac
     4381 agttatcttg cagatagtga accgatgtct atcatgagtg gtgcgttaac tgctgcaaca
     4441 ttaaatcttg ggctagataa gaatttaggt tatgcatatt tagttccatt caatagtaaa
     4501 aacaagcaaa caggaaaatg ggaaaagaaa gctcaattca tgcttggcta taaaggatat
     4561 atccaattag cccaacgatc aggtaaatac aaagcattaa atgtgatcga agtttacgaa
     4621 ggagaactaa aaagctggaa ccgactgaca gaagagtttg agtttgatcc aaatggtaga
     4681 acgtctgatg aagtcattgg atatgttggc tatttcgagt tactgaatgg attcaaaaaa
     4741 actgtctatt ggaccaaaca agaaatcgaa gctcatcgga ttgctaacaa taaagatcgc
     4801 gataagacaa agttaagtgg tgtgtgggca tctgattaca atgcaatggc acgaaaaact
     4861 gttttgagaa atcttctttc taaatgggga atcttgtcca tcgaaatgca agaagccacc
     4921 acatcggatg agagagtcca aagggttcaa gaagacggca gcattattgc tgaaacagaa
     4981 gttgaagaag atattcctga aagaaaagaa gcagaggtta tatctgaaga aaatgaagat
     5041 gtacaaactg gattatttga tgcatctaat ccgccgttaa acaaataatg agggagcttt
     5101 ctcccttgct tttctagagg agaaatacga atgaacacag gatatgtcaa attacatcga
     5161 aaagtgatga attcattcgt ttggaccaat ccttatatgt ataaattatg gaacttgtgt
     5221 ttgatgaaag cgagtcatga gaatcgcaag atacttttta atggaaaaga gatacaagtg
     5281 aacagcggag aattcgtcac agggcgcgat gctatcacat ctgagatgaa cgaaggcgtg
     5341 aaacgtgaac atcaagtgaa cagcggttct gtatggagat ggctaaaaca atttgaaaaa
     5401 aacggaatgt tgaacatcaa atcaactacg aaatacagcg ttatatcaat aaaaaactgg
     5461 tctttgtacc aaagcagtga acaacaaatg aacatcaaac gcacaacaag tgaacaacaa
     5521 gtgcacacaa acaagaatga aaagaattat aagaatgaaa agaataataa aacatcatcg
     5581 tcgcaaccac gcaaaaagcg tgtttacgac accgactcag tttactacat tctcgcggag
     5641 gagttattca aacagatttg tcagaatcag gaaatcaaaa agccgaatct gcaaagttgg
     5701 gcagataaca ttcggaaaat gatcgagatc gacaagcgga ccgaaaacca ggtacgggga
     5761 atgattgaat ggagtcagca caatgtgttt tgggcatcga atattttatc tgctaaaaaa
     5821 ttgcgagaaa aatacgacac aatggcagcg caagccaatc gtgattataa aacaaaacaa
     5881 actaaaacgc ttgaatacga gaaatttagc acagatgagt tgcctatttg agaggaggcg
     5941 taggcatgga aactgttggg gaaatcatgg aaaagctgat acagaaagtg cttgtccaac
     6001 gtggcgaatg tcctgaatgc ggacagcctt tgtatggatg gcgtacgaag aaccctgatg
     6061 gctcagaacg ttgtaagcca acctgtatgc aatgtgggta taaagcattg cgagttcagg
     6121 aagacttaca aacagaacga atttacaacg agagcctgaa agcaagagca atcaattttt
     6181 tcaaaggtgg ttctgttgtg cctaatcaag cgttgtttga ttgcacattg cagaattatc
     6241 aaattgtcga tcaagaaaca agacaagcgg ttgaagtaac caaacgcttt gttaattcag
     6301 tcttgttagg aaatccaagt caccttgttt taactggaaa acaaggaaca ggtaaaagtc
     6361 acctagcgat ggcagcggct tgggaagtct tgaagcgatc aaactacgat aaaaaaatct
     6421 tatttatcgg gttacaggaa atgctggatc aaatcaaatt ttcgtacaac aatcctgaac
     6481 tcagaaaaac gattgaggga tcgttgattg cagatatcaa aacagcggat ttagtcatca
     6541 ttgatgatat cggttcagaa ctaggaaaag atgcatcaga tagtcgagcg tttggcataa
     6601 acacgctaaa ttcgttcttg gatgcacgac agaacctagc aacgattatc acaacgaact
     6661 tgcttggtga agaactgaaa aaagcttacg gtacgagaac aatatcaaga atgtttgtca
     6721 actctgatgg atttacgatg gtattttctc aaacagcaga caagcgcata aaaccagtca
     6781 aaggagcgat cgcatgaatt tgactaaaca agaaaaaaga atctgtcgtc agataatgtt
     6841 gcaaattata ggtgatcgtg acatggacga attatctcaa caagagagtc gaatggttcg
     6901 gaagataagt aagctaatta tttatcggga tacagaaaga tttctcactg ttttaggtaa
     6961 cgtctacgag aatccagagt tattggaggt agagtaattg ccaaaaatat tagatgcatg
     7021 ttgcggtagt agattgttct ggtttgataa gaacaattct gacgtaacat ttatggattg
     7081 tcgtcagcag tatgaagaat tatcaacagg tcatgtgatc aatgttgatc cagatgtggt
     7141 cgcagacttt cgcgatatgc cttttgaaga tgatgtgttc gatatggttg tatttgaccc
     7201 gccacactta agacatgtcg gcgaaaactc atggcttgcc aaaaaatatg gaaaattaga
     7261 cgaactttgg ccagaagaca tcaggcaagg ttttgcagag tgtatgcgag ttttacgacc
     7321 ttcaggaaca ttaattttta agtggaacga ggaacagata ccactttctg atgtgttaga
     7381 ggctattgga gaacagccat tgtttggtaa taaacgaagc aaaacacatt ggcttgtgtt
     7441 tatgaaaaaa ttcagctaac ggaggaaaca aaggaggaaa agtaatgaag attgtattaa
     7501 ataaatgttt tggtggcttt gggttgagcc atgaagcaaa aatggaaatt tttaaaagaa
     7561 aaaatattga agtattccca tacatcaata actttagcta tgactcagat gatgaataca
     7621 cgagatacac aggccaaaag ctaggttcga tggattttat ctactatttc aaaaaagacc
     7681 cgaaaatcga caaagttaca ggaatttata gcgaaattga ccgactgtac ggaattgctg
     7741 atgattccag tttttcaagt gattcaaaca gaggtgataa ggacctcgtt gctgttgtcg
     7801 aaaaactagg aagtgaggcc agtggaccat atgcaagtct taaagtcgtt gatatacccg
     7861 atggggctga gtgggaaata agtgattatg acggcgttga aactgcacat tatggttttc
     7921 aaacaggtag tatttagtcc actaatgaca actaaagagg aggcagaagg atgagtgaag
     7981 atgaatactt tgaacagtag tctattaacg acagagattt ttaactggaa aggggtgtag
     8041 tcatggacgc atcggaagta gtaaataaaa ttaatagtct caaagaggtt ttcggagacg
     8101 tcgaagtagt gataaacgca caaggctatg acaacggatt ttttaagcag attaccgaca
     8161 ttagcattca gcaaggaatg gaagacgaag atggaaactt tatcgatgaa gtagccattt
     8221 tagtgacttg cgagtaagta attgacagct aaagaggagg cagaaggatg aaaaaattgc
     8281 accaactcat atctgagaaa gaaagcgaac tccaaaattt agaagatagt ttgggattgg
     8341 ggtttccaat tgttgagcaa gctaaaatga ctcaaatcag tcatctacga cttgaattgg
     8401 aagatttaag acaaatagaa aaatcaattc aactcaacga caaccagaaa atcgtgttgg
     8461 agtggttgaa aagcgagaca attttaacta gagaagcacc aatattatct gttaatgctt
     8521 tttctgataa aaatttacta ggaaaattac ctgataaagt acgcaaagct tataaactat
     8581 tggcttgtaa acaagaatat gaagtcctat cagcattcgc tcaatgggga ttagaacagg
     8641 aggaagcgga atgaacaaca gacatcgcag aataacaaaa ctaagaaaac aggaactgaa
     8701 tgtactaaag acaaagtttg aaaaagaata tggaatttca gcagaagaaa catataaagt
     8761 ggcaagtcag tttgttgctg atgcgagtaa tgctattcgt aagtttggga tttcgatatt
     8821 aaatgatgat cgtaaatggg aggaaatgag atgaaaataa aagacggatt ttacgctagt
     8881 agtcatggta tcggcggttt aatgctagac atgccgataa agaaccctaa aacacgtcag
     8941 aaatcaaaat tcaaaatcgg tgacatggtc cgatgtaaag cagaagagtt catctatccg
     9001 tttcgtggat atgtagagca tgtctataat cattcagcaa tcattcacat tgaaaacacg
     9061 atggaatgcg ataagtggtt agcgaaaagc aaagataatt tagcagtggc tcgtttggtg
     9121 gatatggaac taatcaatga caaataaaaa agccggatcg ctccgactga ttcaataaat
     9181 ccaacacatt tattatatca cataaaggag cggtttgact tgatgcaatt gttacgagag
     9241 gtagatttca aacagacaag atgtaatgcg agagatgtgc tgaagaactt tcggcgtttg
     9301 gagcggatgg caggtcgctc tttgatagat attaagtcgc cgattattac ggatatgccg
     9361 aaggcaccga agcacggcaa taaggcagaa gacgcgatca ttcagatgat ggatatagaa
     9421 gcggagagag acgcaatact agcggctttg atggctctta gtctgattag ccgtcagata
     9481 ctctactaca gcttctgtga cgtaaacaag cactctaatt atgaaatagg gcaattgata
     9541 cgaggatacg gagagaagaa tgtagagaag ttgaaatcca tcgcattaat cgaatttgca
     9601 gaagcataca aaaaaggcgt gttagttcag tatcgttgat tttgtagggt ttttgtaggg
     9661 atagtgtagg gtttttgagc ggtttaacgt gatattatgg tagtgtcgaa agattagtga
     9721 taggtctgag acaaaataaa atgtaaggga ggaaatctcc ctcatcgttt taacttaagc
     9781 ttcgatagac agcaacggaa atattaagaa taaggatgtg aatttcaact ccttctaaat
     9841 tgttcttatt atctatcatc cgttgttgtc tattaattta tgcatcggag gaaaaacgaa
     9901 tggataaaga aatcaaagta actgtcaaat tagatttgac tgaactaaaa gaactgctca
     9961 acaaggctag tgaccaagtc gaacagttac aagaaacttt agatgaaatt gctaatttta
    10021 aaatccaagt ttcttagcag tatatttttt agcagctgca ctcataaaat cataccaagt
    10081 atcagaaaaa tataacttaa ctaaataatt aaaaaaggtg ggtaaataga aatgacggcg
    10141 ttaataattt caatttttgc gctctgtctt aatgtctata tgattggatt taaaaatgga
    10201 caaaataaaa aatagtagca gccgagaata attttatagt gtcactgtgg cggaaataga
    10261 agacgcaaag gtggaggtag gaagcgtatg gcgcactatc gggaccttgt acaaaactag
    10321 aaaggactag tacgtgtgtg gtgcgagccc tagggaggaa caggataacc gcctgtgtgt
    10381 aggttgctat tacatattag atcactcttt gagtggtctt tttatttaca taaaggaggc
    10441 tacataatga gaaactactg gtatatatcg ctaactaatg aatatcctcg aaccattgat
    10501 gattgttcag tgcgtgttgt gcgttctgtc caaatcaaaa agaagtactc cattgttgaa
    10561 atgaccagag aagctacgcc aaaagagatt gataaatgca aacttcttta ttgcggtcat
    10621 ggtttctatg atgaaccaaa cattcaaaat aatattaaca agaatttgag ggattagaat
    10681 gcaagaaatg gcttaaaaat ctccaatcag gacaaatcaa gttagacaaa gtttccgatt
    10741 taaagatatt gattgaagct gatttaatgc taaaagatat tgaaaattag aaaacaaaac
    10801 tcaacctaag aagattgcga ggtggtgtgt attgaatggc aagacaacgt gatccaagac
    10861 gtgatgaagc caaaagaatt tggttagaat ccaacggaga aaagcagtta aaggaaattg
    10921 catctgaatt aaatgtttca gattctcagg ttagaaaatg gaaatcgcaa gacaaatgga
    10981 gcgctgaatt gaaaagtaac gttaccaatg gcaaaagtaa cgttactaat caaggtggcg
    11041 ctcctattgg taatcaaaat gctaaaggta acaaaggaaa cagcagagca tcaccgccaa
    11101 agagaaataa gaatgctctt aaaactggtg agtatgaaac aatatttttt gacacgttaa
    11161 ccgataatga gaaggacatc tattctagtt tgaatgatga tccttctttt gctttgtccg
    11221 aagaaatacg acttcttaaa ataagacaac ttcgaatgat gaaaagaatc caacaagctg
    11281 aagctggact aaatgatgaa gaagtcgaac gattgcagca gctaagaaag attaaaactc
    11341 cgattgaaaa aaatggtaaa aagctagaaa tcaagcgtga ggttatgcaa gatgtgcaga
    11401 ttagcagaaa aaaacatcgc aaaattgatg atattctttc aattgaagat tcattgactc
    11461 ggattagcaa ccagttagct aaagccatca agcaaatgaa tgaactttat atgaatgaat
    11521 acagaactga tttaattaaa gctcagactg ataagatcca agctgagaca aatgaaattg
    11581 gcggaaataa ttcaggtgaa gaaatagaag aatggaaaca ggcagtttta aatgccgcaa
    11641 acaaacgggc ggtgaaagaa aatgaataat gaatttattc cttttgctga tattggttct
    11701 gccattgatt attactatga taaaccagta gctttttgcc aagatatttt gcatttgaat
    11761 cctgatgaat ggcaagaaaa tgttttaaat gatttagctg aattttcaaa ggtttctgtt
    11821 cgttctggtc aaggagttgg aaaaacagca ttagaagcag gagcaatact ttggttctta
    11881 acgtgtcgac cctacgctaa agtaatagca acagctccga caatgaagca actttacgat
    11941 gtactttggg cagaggtagc taaatggtta aatgatagct tgatcaaaaa cttactgaag
    12001 tggacaaaga ccaaaattta tatggttggt gattcagagc gttggtttgc tacggctaga
    12061 acagcgacta aaccagaaaa tatgcaaggt tttcacgagg accatatgtt gattgtggta
    12121 gatgaagctt ctggtgtgtc tgatccaatt atggaagcta ttcttggtac gctatcaggt
    12181 tttgataata agctgttgat gtgtggaaac cctaataata ttgaaggtgt cttttacgat
    12241 tcccacaatt cagaccgtga taaatacaga gttcataaag tatcaagcta tgatagtaaa
    12301 cgtacaaaca aagacaatat agaaatgatt cttaaaaaat atggaaaaga aagtgatgtt
    12361 gctcgtgtcc gtatttttgg agaatttccc aaaggtgcgt tggattcatt tatcagtctt
    12421 gaaacggttg aattggctac agaaaaacaa attagtgatt ctttagtcaa taaaacaacg
    12481 gttgctcata ttggtgttga cgtagctcga tatggtgatg attctacgat tctctttcct
    12541 agaattgcta ccagggcatt ggagtatgag aagtattcaa aacgtagcac tatggaaaca
    12601 acaggatatg tcatcaacat ggccaagaat ctaatgagtc aatatccgag tattgataaa
    12661 gtgatgatta aagtcgatga cactggtgtc ggaggtggtg taaccgaccg cctagaagaa
    12721 cttatagaag acaagcatta tccttttgag gtgtttggag tgaataacgg ttcaacatca
    12781 gaagacgatt tttacgataa tttaggtact caactatggg gaaacatcaa ggaaatgtta
    12841 gaagaaaata tgacagcaaa tcttaacgga gaacagcctg ttattgaatt gccttctgat
    12901 agttcgttaa tcaaagaatt aagtactcgc aaattcaaaa tgacaagtag aagtcgtata
    12961 cgtttagaaa gtaaagatga tatgaaaaag cgaaatattg gtagtcccga tattgctgac
    13021 gcactggctt tagcgtttta tgagccacca agtcactatc aatttattca attttaggag
    13081 gtgagttttt gattagtaca gtattatctt tagagagata taagaagcta cgtgttaaat
    13141 atgcaacaca aattgaagat ggaatgtttg atccgaatgg ttttatagaa tatatgaaac
    13201 cattttttgc tgatcgcgaa agaaaatatc tagcttatac tagcgaaaag aatgaaatag
    13261 acaatagacc aaagcctaac actgatattg taaaagttaa taataaactt catgctggta
    13321 tgtattcaat tgtcgtagac caagcagtca atcattttac tggtatacct atcaaatggg
    13381 attacgatgt atcggaacaa aaaagaacac tcattcaaag attaaaagat aaattcttaa
    13441 aaaatgatat agaacttcca acagttccag aagcttttaa caaattaaca agcaatcttg
    13501 attccatgag attcgcaatg cttgattctg aaactgcaac ttttcaagga gcttgtggag
    13561 tagctttccg attgttagag cctgtggaag aagatgatgg ttggaagtta agagcaagta
    13621 atattgaacc ttggagagca gaaagatatg gaaatgccgg aatctatatc aaagaaaagt
    13681 atgactctta ccagaaaaaa ttttttcaag aaatgaaagt tatgacaaga aataaaattc
    13741 tgacatatgc ttgctatggt gatttgaatt ttgttacaag cggaacgttc aaaaaaattg
    13801 atgagaccga taaccctttg gggacgatta ccttggcaga atttaaaaat aatacgaatc
    13861 gttattgtga ttttgaagta gctgaggaaa ttggagatgc aattgatcgt gctttgtctg
    13921 atcaacaaaa cgaaatcgaa caatttaagc ttgcgtacat gcttgttact ggcacaacaa
    13981 tgagcaaagg cactgctaaa gaaatgatga atcagctagg gattatcaac ttaaaagacc
    14041 ctactgcaaa agctgaatat gtcacaaaaa aattagcaaa agatttcaat gaatatcata
    14101 tggatctatt gaaaaaacag ttttacacca tttgtaaagc aatcgatttt aacgatgagg
    14161 tgtttaaatc aaacagttct ggagaagctc gcaagtggca aatcattagc ctagaagcga
    14221 aaacaaatac taaagagcaa tattttagag aaggattgaa agaatgcgca gaaacaattg
    14281 ctgcttttct taagtttcat gacaaagtag aaattgagcc tgaaaaaatt atttttactt
    14341 tctctagatc tttgccaact gatttaagtt atttagctga agctttacct aaacttgcac
    14401 catacgtatc caaacgaact attcagagcc aaattccatt tgtaacagat gttgattatg
    14461 aaaatgaaat gatggaattg gaaagtggaa gtgcttatcc agatagtgaa tacaattttg
    14521 gcggaggtgg caatagtgac gatagaaacg aagtattgga ccaaacgtcg agaactggag
    14581 gatcaagcaa ggctcaaaca agaaaatcag acacttaaaa aattaactag tgtatttcct
    14641 gaagcactga aagagataca agcaaaacta ttatcacaag ctgacttaca caatatcact
    14701 tatccagaaa tgatggagtt ttacagtaca agtaatcaga aaaaatatcg tgaatatgtg
    14761 gaaaaaaatt ataagtcatt aaaaatgtat gatgcaaaat acaaagagtt tatcgatgaa
    14821 ttttttccac catttgacta tgcaaaagtc aatcgcttat tacaaatacg atcagatgta
    14881 tttaaaattc ttgcagaata tgcgatggat gcagatgtga atcaatattt ttctgatcgc
    14941 ttagaggaaa ttcttcaaag aacatattct tctaatgcta atgtttttgt tcaactttta
    15001 aacgttgata taccaaatta tttaccagaa aatgaaatta aacattattt gaactatcca
    15061 tggtcaggaa agacattttc aagaagactt tggggaaata tttcatcgct tgaacagaaa
    15121 ctctctaatg ctattgtaaa aagtgttgct agtggagaag gcgttataca cgcattaaac
    15181 accatgagat tagactcaga aatttgtgac atgtttaagt tagaagaatc aaagtataac
    15241 aaagcgatag aaaatctcgt tcgaacggag tatgcaaaat ttgcacaaga tggtattgaa
    15301 aaatcatatt tagaaacagg tattgaggaa tacaacgtat tgactgcaaa agatgagaga
    15361 gtttgccgga tttgtggagg aaaggcaagt aagaatccct ataaactgaa agatgctgtc
    15421 ataggtgaaa atcgagcacc tttccatagt cgttgtagat gtacggatgt tcctaattta
    15481 ccaaaattag gaaaggatat tgatgaagaa tatgaccgtt tatttggcga tttattagat
    15541 gagtttgcac atgattcttt tggaattaat ttgaaacgga ggaagtagaa tgaaagattt
    15601 ttttgaagca gtactaacaa ttaatgtaaa tgctgatatt gcagaagcct acaaaacagc
    15661 tattgagtct gagaaccatc ctaatggctt gagagaccat tggaatggca attatgccta
    15721 cgtggttatt ggcgatcaaa ctgttaatta tcaagataat actccagttg ataagaatac
    15781 cgttaattta acgattcaat tattatctca ttcattacca aatttaaaag aaacagttga
    15841 ttggtatgaa aagatgggat gtattgttgt tagaactgac tacaaagaag gaaagtctag
    15901 taattaggct tttttatttt gtccgaaatg acgttaaact agcgcaatac tgggcttggt
    15961 tgaatggtgg ggcgcaacta ttaaaactca aagcaatgcg gggcgtgaaa acgaatcgtg
    16021 gggcgaaagg agaatgagca tgaaacacaa atcattaatg ccaatgaatt tgcaatactt
    16081 tgccgaaggt gacgatcaaa agttttcttt tgatgacttc aaatcttttg tggaatccaa
    16141 tgaagaagct caaaaattta ttcagtcaca atctcaaagt gttgccgaca aacaattgga
    16201 agcttggaaa caaaataact tagataaaat taaacaggat accatcaagg aatatgagga
    16261 atctaagaaa aacaagtcac ctgagcaaat tcaactggaa aaactacaag ctgaatttga
    16321 agcagaaaaa gcgttgcgtg tgacaagtga taataaagca tttgttgcag aacaaattgc
    16381 tggattagaa ctagatggag agttaaaaga gtctatttct caatttatgc taaataatct
    16441 tgttagttcg gatacagatt tcactaagaa tgctgttgaa ggttttacaa gtgttttgaa
    16501 tgcaattaat gagaaacatg cagatgcatt aaaagaacta caaatgaagt ctgcatttgg
    16561 tggaactcaa caatcgaata accaggttca gcagaacaat gaaacattaa caaatccaga
    16621 agaacaatta ggacaaattc ttcaacaatt taactaggag agtgaaaaat tatgaaaaaa
    16681 acatctttaa ataatttaga gtatttggat atttcaccag cgattaatgc tatgcaagta
    16741 ccaaatacac cttttttaag ctatttactt ggtgctggaa aaacagagcc agcaaactcg
    16801 acagaaatta aatggcgtga atatgatatc aacaacgatg attcttctga aaaacttgag
    16861 ggcggagaat atccagatgc tgaatcaggt cgaacttggt ttaacaacta tactgaaatt
    16921 tttagaaaat caacctctgt atctggtaca ttagatgcta ttaatgtgaa tggagtcgga
    16981 aatgaattaa ctaatcaagt agcactacgt ggtatggaaa tgaaaattga tttgaaccga
    17041 aaattgatta ctggtgtaaa agctgatgaa aatggttcta aaggtcgtcg aatgaatggg
    17101 attttgaact tgatcaattc agcaaataag gcagaaacag ccactgcggg tgcagtaaca
    17161 agaaaagata tcgatacttt atttaaattg atgtatgaaa aaggttatat gggagaaaaa
    17221 ctatgcttga tttctccaga tatgcaggag ttaatgactg atgagttaga tggaaaatca
    17281 acaaaaattg ttcagttcgg ggaaagagta acttttggat tgcaaattgg aaatatcgtg
    17341 tctaattacg gtacaggtat tgctctacta gaaccatcat tgccaaaagg aacaattgcc
    17401 gcaatcgata ctaattatgt gaaactacgt ccattacgtg aatggagagc agaagaactt
    17461 gcaaaaacaa cggattctag acgtatcggt cttgtaggtg aatactctct tgaatacaat
    17521 gcttcaaact ctggggcaat tttaaattta aagtctgaat aaaagggagt tagtactccc
    17581 ttttttgata ggaggaatta cagtggtaaa aaaagatgaa actaaaaaag atgaagtcgt
    17641 gaaatataga gtaggtaaaa ctaaaaattt tgttgggttt gttcatccta aaactcgtag
    17701 atttatcaca gcagattcaa ataacgaatt tatcatttct atagatgata aagaagcaat
    17761 tgcaattttg gaagatgcaa ttgatgttaa tgaaatttag gaagtgatct gatggatgaa
    17821 tcgctaaaaa cggaaatcat tgagtctaca aaagaagatt ttccagattt gagtgaagaa
    17881 cgcataacta atttattaga aataattttg ctagaaattg aatcatacaa cacttgtaaa
    17941 aatgatattt catgggaaaa gttaaaaagc gtgattagtg aagtgttgta taaaataata
    18001 aaaaatgaat cagaaaaaac agtatcttca gttagacgtg gcgatacaac gattagttat
    18061 gcttcaacaa caaatgatgt tagtgagtta cttctaggct atggtgattt gatacgaaga
    18121 gttattggtt gtggaggatt ggagtttttt taatgaatga agcagatatt ttagaaacta
    18181 cttatgaaga tagttgtatt attgaaagac tgacggacat tgaagattct aatacaaata
    18241 ttactattca agattacaaa aaagtatatg ataatcctat ttcttgcgct ctttcacaag
    18301 gtcaaatcga tggactagca gtcatagaag atggagagat ggtaaatgtt tcaactgaca
    18361 catataaatt atttgttcat cctaagatta aactaaaaaa aggagatcga ataacaataa
    18421 ctcaaaaggc cagtggctta attttttctc tatttgctac taagcctttt tactatccta
    18481 gtcattgtga agtgaatttg ataggaagtg agaaaaatgg gtaatctcaa atatgaatca
    18541 aatgcagaaa agatcattga gaattttaaa aatatgactg taattgctca aaaagaagga
    18601 atatccttcg ttaacgattc aatgaataaa gtcgttagtt tagctaaacc attaactcct
    18661 gtaaaatcag gtaatttaag gcgaggatat cgtgtagtaa aagctagaaa actatcaagc
    18721 ggtcgaattg ttggagcagt tataaacaat gaacattatt ttaaatatgt agaagaaggt
    18781 cataggacta aaaatggtgg ctttgtcaaa gggaaattca tgttaactcg tgcaacgaat
    18841 cttgcaaata tgtcttatat tcctcgaaga tttaaacaaa tggcaataaa aatcgttaag
    18901 aaaggaaagt aacatgaaag atgaaatcat tgctgcaatc agtagcaaat taaaagaaat
    18961 ctatcctgat gggacaatat atcttgattc agttatgcag tcaactaaag atttttattt
    19021 cgttttatca gtaatggaat ctggaactga aaatgtagga attgatattc aaaatgtttc
    19081 tttcttaatt gatattgcat tgattgataa taaacctaat agaaatttaa ttaatgaatt
    19141 agtctcacgt tgtgggactt tttttaatac gattacaatc gatgagcaaa tattatttcc
    19201 aaaagcctat ttacctgatg aagcagatgg tgttcaacat attcgtttta cattagaatt
    19261 tccacaatat attgaatgga gtgaaagata aatgggagaa aaaagaagta aaaccggaat
    19321 tatttctgtc gaaaaaccta cttggtttcc tttggaagat gagacaggga attttccggt
    19381 atatggtact gcgttgccaa tgggaacagc agtaagtatc aaaccaacag ctaattatga
    19441 aacaacacaa gattatgggg attcagtggt tcaagatcaa tttacagctt ttggtggtgc
    19501 agaagttgaa ctggaagcaa atggatatac tcataaagtt ttatctacaa ttactggagg
    19561 gaaaattgtt aaaggtggtg ccttgcgttc tggagaagat attgcgcaag atggtgcgtt
    19621 tgcatataga cgtaaaaaat cgaatgggaa ataccgttat acggtctttt ataaaggaca
    19681 gtttgctcta gattcagatg aaacatcaac gattgaagga agtaaagtaa gttttactca
    19741 tccaacttgg aagggttcat ttgtagatgt accaggactt ggatatatgt attcagttga
    19801 tgaagatgat gaaggcgtgg ataaagcaat gatcggaaat tggtttacaa aagtagcaat
    19861 tccaattgaa gaagcagaac tttcaggagg tacagaataa tgtcaaaata tcaaacaacg
    19921 attaaattaa cgaaaaaaga tgaagaaggt aaatatgagc aagtacaatt taaatctgct
    19981 gaatttctac caggcccagt cgtagaagaa gcagcagaag taatggaggg aatgcaaaat
    20041 gctgtagatg gaaaatcagt atcagaagca ttaagtcgag cttattcatt tattgcagat
    20101 attttgtttg aaggacagtt tactggtgaa gattatcgtc aagggatcga tgctcgagaa
    20161 attgcttcgt tgacaggtaa gttattaaaa tctgttactg caggctttga tgaaacttat
    20221 acagaaacga aaaaaaagta agcgaagctc tcaaatatcc tttttttaaa cattcgatta
    20281 cttatcgaga attagattta aagacgcaat tactcgaagc aggttggacg ttaccagaaa
    20341 ttgaacgtac tgactttgac gagttaatgc gtctttttgc ttttcgagat gcagtaaaag
    20401 agcatgagga tgttgagtac tacgataact tcacccaatt ttaggaggtg atactttgaa
    20461 taacgatgac ctaattctga agatgatact agatgaatct ggttttactg ccggtatgaa
    20521 taatgctgtc aaaaagttga actcttttga tgaaacaatc gaaagaaaaa gtagaaatag
    20581 tggcagttca ttaggtagta tttggaaaat atttgctgga agttttctag ctagcggagt
    20641 aactagaatc gtaggagctg gctttgatct aatcaagggt tccataagtg gagcggttga
    20701 tcgagtagat acgatgaata acgctctacg aaatttccaa aatatgggat ttagtaattc
    20761 agaaattatg aagaatatcg gaaagaatgg gcttttatct caaggtattc aaggacttcc
    20821 tactgctttg aatgatgcga taagtcatgt tcaacttctt gcttcttcta caggtgattt
    20881 aactcgttca actcaaatat ttaaagcttt aaatgatgga attcttggtt tcggtggttc
    20941 aactgatcaa gttaatgaag ctgttattca attatctcaa agtttctcaa acggaaaagt
    21001 agacgcacaa acttggaact caatgatcaa cgctcaactt ggacctactc tttctgctat
    21061 tgctaaaaag atgggaatta caatgggaga tctgaaagaa ggtttatctc aaggtaagat
    21121 ttctgttgaa gaattccaaa atcaattaat agaaatggat accaaaggtg gcggaggact
    21181 taaatcatta agtcaaatcg ctaaagattc tactaaggga attaaaacct ctatacaaaa
    21241 tgcaaaaaca gctgttacac gtggtgttgg tgaggtaata gaaggattaa ataaagcatt
    21301 agtagattca gatttaggtg gatttaaggg aattattgat aaagtgggca gttcaatgga
    21361 atcgttctta aaagtaattg ctgcaaatat tcctacagca gtatcatttt taagtaattt
    21421 atttaacgaa attcaaaaat ttggttctgc tttgaaattc atgatgccct ttcttgttcc
    21481 tgcagctacc gcttttggag cgttcatgtt tcaacttaaa ggtataccag caataataaa
    21541 aagcttcaat aattttaaga atgccataat tggcgttgga aattcattaa agattatggg
    21601 ggcaatagct gctgctaatt catttgtttt aattattggt gcagtcgttg gtgcaatagc
    21661 tgttttcggt tactttatgg caaccaatga agagcttaga aacaaggtta tatctatttg
    21721 gaatgatgtg aaagattccg taattggtgt attaaaaaat ataaaggact ggggaattga
    21781 tacttggaat tctgctaaag aaatggcatc aaatgcagtt gagggtgtca aagatgcttg
    21841 gtcaggaaca aaggaatggt tttctaacac ctggaaaggt attaaggatg gggccacagg
    21901 tttatttgat aaaacagtag agacttcaag aaatgcagtc gatagtgtaa aaaatgcatg
    21961 gtctaatatg aagaaatggt tttctgatac ttggcaaagt ataaaagatt cagccagaga
    22021 aaaatggaat ggaatcaaag gttctattat gtcagttgct ggtccattga ttacaggtat
    22081 aaagaatgca tttttacatg ttacttttta tctagagacc ttatggaata atttagttga
    22141 gattggtaaa aacgtctttg agattttaaa aaatgttata cttgcgccgg ttttgtttat
    22201 tacctccatg atttctggtg gatgggaaga aacaaaaaat aatatgattg ctgtttggaa
    22261 taatattaaa gaaagtgcca taaatatttg ggaatctata aagaatatat ttgtaagtta
    22321 ttttacaaat atttattttg ctgcactcaa tatttggaca gggtt
//
LOCUS       DAZAOD010000041        22245 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000041 DAZAOD010000000
VERSION     DAZAOD010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.042"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            19..540
                     /locus_tag="ACHDPO_001545"
     CDS             19..540
                     /locus_tag="ACHDPO_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3369169.1"
                     /translation="MHIGDKIHKLRRLNNETMNDLVKQTGLSKSWVSDIESGKKQRAD
                     FNKICAIAKHYKVSLEYFQDDYLDSDEHEDIIPLTDETRVKSVKSLEQSLKYLNNKQE
                     PNLLEIKLKDTDSVPEVYYKGQKLEGLIDVSYHYHTTTDVVAGSTNDINMEYLGEVTK
                     YPDIKTIGHKRDV"
     gene            637..858
                     /locus_tag="ACHDPO_001546"
     CDS             637..858
                     /locus_tag="ACHDPO_001546"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFN3369170.1"
                     /translation="MCQECKRRGRNTRGTIIHHIVEAREDLSLFWSVDNLECICVACH
                     NREHPERSGGKKKPKPKSHIVKMYSTPER"
     gene            complement(1015..1179)
                     /locus_tag="ACHDPO_001547"
     CDS             complement(1015..1179)
                     /locus_tag="ACHDPO_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HFN3369171.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGREVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            1282..1803
                     /locus_tag="ACHDPO_001548"
     CDS             1282..1803
                     /locus_tag="ACHDPO_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFN3369172.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1790..2230
                     /locus_tag="ACHDPO_001549"
                     /pseudo
     CDS             1790..2230
                     /locus_tag="ACHDPO_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
     gene            complement(2270..2428)
                     /locus_tag="ACHDPO_001550"
     CDS             complement(2270..2428)
                     /locus_tag="ACHDPO_001550"
                     /inference="COORDINATES: protein motif:HMM:NF024064.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HFN3369173.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            2521..3282
                     /locus_tag="ACHDPO_001551"
     CDS             2521..3282
                     /locus_tag="ACHDPO_001551"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFN3369174.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENFDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            3469..4821
                     /locus_tag="ACHDPO_001552"
                     /pseudo
     CDS             3469..4821
                     /locus_tag="ACHDPO_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
     gene            4837..6057
                     /locus_tag="ACHDPO_001553"
     CDS             4837..6057
                     /locus_tag="ACHDPO_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFN3369175.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDAEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALIKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGGNEGLKVKFASNVDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGSNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTNSSKSVAENG"
     gene            6092..6769
                     /locus_tag="ACHDPO_001554"
     CDS             6092..6769
                     /locus_tag="ACHDPO_001554"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFN3369176.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGIDCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAETPQEETLLQKKLKA
                     LNGGKNE"
     gene            6766..7962
                     /locus_tag="ACHDPO_001555"
     CDS             6766..7962
                     /locus_tag="ACHDPO_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010905933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFN3369177.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRQFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     INPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSNWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIINVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTSIANE
                     VPVTNG"
     gene            7977..8300
                     /locus_tag="ACHDPO_001556"
     CDS             7977..8300
                     /locus_tag="ACHDPO_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFN3369178.1"
                     /translation="MILDPKMDLDEIKNALKIDTDDDDVEVRRAVQAAIAYIRGAIGN
                     DKPSFYKQENDTVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKARYL
                     LFVEE"
     gene            8304..8639
                     /locus_tag="ACHDPO_001557"
     CDS             8304..8639
                     /locus_tag="ACHDPO_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFN3369179.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVRTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            8636..9031
                     /locus_tag="ACHDPO_001558"
     CDS             8636..9031
                     /locus_tag="ACHDPO_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFN3369180.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEKLQQNT
                     PYWDGTKSNGKRGSYMQEHAKDHVVTSSVKNGLIEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            9028..9399
                     /locus_tag="ACHDPO_001559"
     CDS             9028..9399
                     /locus_tag="ACHDPO_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369181.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EIFGNYEDFASNNPLTIQFNVQVDVWVSTLKEVDAFYFALDEIMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            9415..9975
                     /locus_tag="ACHDPO_001560"
     CDS             9415..9975
                     /locus_tag="ACHDPO_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFN3369182.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGVNVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLAKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEEMTLQKFKDLVNNKAGE"
     gene            10102..10413
                     /locus_tag="ACHDPO_001561"
     CDS             10102..10413
                     /locus_tag="ACHDPO_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369183.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     R"
     gene            10437..10628
                     /locus_tag="ACHDPO_001562"
     CDS             10437..10628
                     /locus_tag="ACHDPO_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369184.1"
                     /translation="MDQIYKDLIESGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            10628..14473
                     /locus_tag="ACHDPO_001563"
     CDS             10628..14473
                     /locus_tag="ACHDPO_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFN3369185.1"
                     /translation="MAGKGQPAGNIKLGISLDSTNFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKKIEDFGDKSTRSARKLDGLKDKLGSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIDKVGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NKVSDAIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGADKLEEWKVPQYAKGTPNGGHPGGPMMVNDGRGAE
                     AVITPNGQAFIPRGRNVVLNAPKGTHVLTAEETAYMTGNKAPRYRYAKGTGFFGNLWN
                     NVKGFAGDVGNKLKDVVGDVWDFVTDPGALARKVLNGLGVLEGLVKYPLDVGKGILSK
                     ATEALTNKITELFSSGSLDTSMGMQGVYKYLADVAVAVMKKFPGFVATSGYRPGDPYS
                     HGKRNAIDIALPGVTGGSPRYTEAANYAFEKFANKIGYVITNGKVRDRSGQSGTGIHN
                     DWRPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTAN
                     LNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFDP
                     LSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAKR
                     SRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKGN
                     SRTDRDLALDIQKILVRRM"
     gene            14474..15346
                     /locus_tag="ACHDPO_001564"
     CDS             14474..15346
                     /locus_tag="ACHDPO_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage distal tail protein domain-containing
                     protein"
                     /protein_id="HFN3369186.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSENVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            15343..16392
                     /locus_tag="ACHDPO_001565"
     CDS             15343..16392
                     /locus_tag="ACHDPO_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369187.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGADEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            16396..17220
                     /locus_tag="ACHDPO_001566"
     CDS             16396..17220
                     /locus_tag="ACHDPO_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369188.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWSGTALMHDTQTVQPSKKMWQTVSGFLLVWLPYENGQAIGDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            17238..19370
                     /locus_tag="ACHDPO_001567"
     CDS             17238..19370
                     /locus_tag="ACHDPO_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HFN3369189.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDKTNDRIDQTNQQIGDLGKLKKMYSNSIDFGDYD
                     YSGNPNLSAKLNASSFSLGTGATVADDNDEIVFTLDGTNQLSKYASKAQVPVAEGKQY
                     TISCEIMLEDGFTGDPSGIRLQHAYLPGGVVVLQTETVPKNELNTWQTLIGTRTVKYT
                     SDVPNEWYPLFRDIRTLKPTGKVRLRKIKIEEGSTATPYQPNLLDDPYWLGKAPLGEN
                     IANKSVTFPIKSSAYSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRY
                     GNLEPVEGLVDTWGLTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGNTRTP
                     NISEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEI
                     NSQLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSA
                     KLYREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQL
                     SIGADGAIKWRRNSSYGSDYTFAITYTI"
     gene            19387..19536
                     /locus_tag="ACHDPO_001568"
     CDS             19387..19536
                     /locus_tag="ACHDPO_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369190.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPILNWKPKFNY
                     WEGNK"
     gene            19533..19979
                     /locus_tag="ACHDPO_001569"
     CDS             19533..19979
                     /locus_tag="ACHDPO_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369191.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            19981..20118
                     /locus_tag="ACHDPO_001570"
     CDS             19981..20118
                     /locus_tag="ACHDPO_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFN3369192.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            20155..20448
                     /locus_tag="ACHDPO_001571"
     CDS             20155..20448
                     /locus_tag="ACHDPO_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369193.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERSR"
     gene            20471..20668
                     /locus_tag="ACHDPO_001572"
     CDS             20471..20668
                     /locus_tag="ACHDPO_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFN3369194.1"
                     /translation="MILPDKYYQVIKWTVLTVLPALSVLVATLGKAYGWNGTDMAVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            20679..21698
                     /locus_tag="ACHDPO_001573"
     CDS             20679..21698
                     /locus_tag="ACHDPO_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFN3369195.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGVNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            21955..>22245
                     /locus_tag="ACHDPO_001574"
     CDS             21955..>22245
                     /locus_tag="ACHDPO_001574"
                     /inference="COORDINATES: protein motif:HMM:NF014505.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFN3369196.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRG"
BASE COUNT         7748 a         3782 c         4925 g         5790 t
ORIGIN      
        1 gattaaggag gaagagtaat gcatatagga gataagatac ataaattgag acggcttaat
       61 aacgaaacaa tgaacgactt agttaaacaa accggactgt caaaatcatg ggtatctgat
      121 attgagtctg gaaaaaagca acgcgctgac tttaataaga tatgtgcaat agccaaacat
      181 tataaagtta gcttagaata ctttcaggat gattatttgg atagtgatga acacgaggat
      241 attattcctt tgacagacga aacaagagtt aaatcagtga aatcgcttga acaaagccta
      301 aagtatctga ataacaaaca agaacctaac cttctagaga tcaaactaaa agatactgac
      361 tcagtaccag aggtttatta caaaggtcag aagttagagg gattgataga tgtaagctat
      421 cactaccata caacaactga tgtggtagct ggttcaacaa acgacatcaa tatggagtac
      481 ctaggtgaag taactaagta tccagatata aaaacaatcg gacacaagag agatgtgtaa
      541 atgaaagaag ctagacctag agacgagata gacaaactat acaagaccaa acgatggcga
      601 gacctaaggc aagtagtaat agctagggac ttcggcatgt gccaagagtg caagcgtcga
      661 gggcggaaca caaggggcac gatcatccat cacatagtcg aggcgaggga agacctgtca
      721 ctgttctggt ccgtagataa ccttgaatgt atctgtgtag cttgtcacaa cagagagcat
      781 ccagagagat caggcgggaa gaagaaacca aaacctaaat cacatatcgt taaaatgtat
      841 tcaactcctg aaagataagt ttgcagcgaa atgaaggtag cccccctact ctaaaagatt
      901 aaagagtaag gcttgagaag aacggtgctg tccttccttc gtaaaaagac cgcttttcaa
      961 gttttttgga gaaaaaggaa aaagccgacc aatttaagcc ggctttggac gaagctattt
     1021 cttagtccat ttgtttcctt tttgagaagt aggaggtaat cggtcgcctg gatcaatttt
     1081 tacttctcgt ccgccttgga catttccacc acgaggtccc acttctttat aggttccttt
     1141 tggtttattg tcttcgccgg gtttatagag ttctcccata ggaatccctc cctaaaaaaa
     1201 tttcggcaca gcactgccga taacttaatt ataaggattg tgataacgat ttcaatatat
     1261 cttttgaaag aaggtgatat tatgccgcaa ccagcgaaga gtgcaaaatt acaattatta
     1321 aacggaaacc caaataagaa gaataccgaa gaactccgca agcgagcggc cgcagaagac
     1381 aaattaaaaa tggctactga caaaatcaaa ccgccgttat ggctagattc gctaggaaag
     1441 gatacctttg agtttatcgc tgatgaattg ctgtctgtgg atttaatcag taatccggac
     1501 gtccatacaa tggctctcta ctccaattgg tattcgcaat acgtttcttt agaaaaacag
     1561 cttcgaaaac tacaacgaga gtacaagttg aactatgcgc ttgcgaaaaa ggaggcagag
     1621 gcgagaggtg agccgtttaa tgaacctaat gaattaattg gtaatccgct ctctcggcag
     1681 atggatacag cgtcgcggaa tctccgttct tttggcgctg atttaggact atcaccagca
     1741 gccagagcta agttagctat taagatggct gatgatggtg gtgatgacga tgacgacttc
     1801 taatattttg gatatgtcct acacagaacg tgtggactat tggcaaagct atcttgagga
     1861 gcaagcttct tggggtggct ttttaaaatg tccatatccg gaattgttaa ctacttggta
     1921 tgcggaacga ttaatcgatg gaagcatacc agccagcaaa gaaaatattc aagctgctaa
     1981 acggcatatg cgtgatttgc agcgccaagg aacagatgat tttccttgga tctttgacga
     2041 agaaaaaggt caccggccta ttagatatat cgaaaaaaaa tgtaaaccaa ctgaaggcga
     2101 ctttggttcg tttgttttgc aaccttggca gcatttcata attggatcca tgtacggatg
     2161 ggtacatcgt gatacaggag agcgtcgctt ccgcgaggct cttatttttg ttggacgtaa
     2221 aaacggtaag ttttgccgtt taaaaatcgg gcaaaatcgg tgaaaacctt tatttttggc
     2281 tttcttttag taataattcg atagctttat caagcaattt agacatagga accatagttt
     2341 cttccgacat tttttttaat ccttcgtata aatctttatc aattgcgtta gaaattctaa
     2401 ttctgttttt tagtccgtat ttgtccatgt gtgacactcc tttttatttt actataacat
     2461 ccgattccac cgcttgcaac taccatcaat tgatggtagt atataaaaga ggtgagtaga
     2521 ttgaaaaaat acattattta caaacactta aataaaataa atggcaaaat ttatatcggt
     2581 gtcacaaatg atattggcag aaggtggagg agcggtggga ttgaatataa accaccaaag
     2641 aacgaaaccc aacaccacag aagtttttgg aatgcaatac aaaaatacgg gtgggaaaat
     2701 tttgatcatt tgattattga agaagactta acgatgaaag aagcttttga gaaagaaaag
     2761 ttttatattg aactttatga ctcaactaat aagaaaaaag gttataacat cgcaaaaggc
     2821 ggaaatggcg gaataatata taaagttcac cccaaaggaa tgctagggaa aaaacaatct
     2881 aaagaatttt cttcaaatca cagtaaatgg gcaaagaacc ataagaataa ttgtatgaca
     2941 aacggtgatg ttgtatgggg tgttactcac gaacacccaa aaggcatgtt gggaaagcac
     3001 cacagcaaag aatcaattat gaaaaagaaa gcatatagtg gtgaaaatgc tgtaacctca
     3061 aaaccaattg tcgcaattga acgggatgga actaaaagag aatttcacag cgctaagctt
     3121 tgcatggctt actattcgat tagtacatgt gttttttacc gacttttaaa agatggcgcc
     3181 ccttatgtga taaatcctaa agcgaactac agaaataaag aaaaaatatt agctatcgaa
     3241 ggaattatgt tcaaacataa agaagatacc gaggtaagtt agtagattgc gaaaggttac
     3301 taactaccgt aacgcgtagg agttgaataa atataatgct cccaagagtg tccgacagca
     3361 gataatttgc tgaaaatgta cgctaaactg ggccagaact gactgaccga tgaaaatgag
     3421 ggtgacctcc agagtgcgag ataaaaagct cgcagataat aacaatcgaa aacatcacta
     3481 atttcaggcc tttccacata catggtcgct tatgatgatg aacaaggcgc caacgtttac
     3541 gtattggcaa atgctcgtga tcaagcaagc ttgttgtttg ataaggccgc agaaatggtc
     3601 aaacaatcgc cggcgctctt taagaaattt ggtaagccta aacgatcaag tattaattat
     3661 gctcccgcct tttctaaaat ggaaccacgc gcctcagata gccggaaatt ggatgggcta
     3721 aacactcact ttggtatttt tgacgagatc cacgagttta cgaattacaa tctgatcaac
     3781 gttatcaaga aatcaagagg aaccagaaaa cagcctctga tagtttatat cacaactgct
     3841 ggatatgtat tagatggtcc gttgatgtct tattttgagc aaggtgtgga ctgtttggaa
     3901 catttggaag atgacatcga tgaacggact ttctattatc tggcaaaact tgacagtgcg
     3961 gaagaggctg atgacccaag attatggatc aaagccaatc cgaatatttg tctaatgaat
     4021 tttgttggca tgctagatga ctatgttaag gataaaaaag atccaaaaga atatgctgac
     4081 tggattacca agcaatttaa cttgttttcc gatatcgatg agctgtcatt tgtcgatatg
     4141 cctaccatta aacgaaacaa taaaaccatc gatattgaaa cgctcaaagg taagaagtgt
     4201 gtcggtggtt ttgacttgtc cgaaacggaa gactttaccg cagccgtttt agaatttccg
     4261 cttgaaacag gcgaggtatt cattttgcaa cacacatgga tcccacaagc tagatttgat
     4321 cgagataaca atcaagagcg tatcaaagcg tgggagaagg tgggagatct aacgattatt
     4381 cctggtgatt acgtcaatta tgaatacgtc ttaaattggt ttgtagaaaa ttcgaaaatc
     4441 tatgacattg taaaaatcaa ttatgacaag gccaaggcgc tacgattaaa taaagaacta
     4501 gaaaatgcag gatttgaaac caacgagatt cggcaagggt ttctatcatt aggtgggcca
     4561 atgcaaaact tcaaggaaat gctattggac ggtaaggtga ttttcaacaa ttccaagctt
     4621 taccgatggt atctatccaa cgtcaagctg gtgatggatc gcaactcaaa ctggatgccg
     4681 tctaagcagt ccaagagtag aaaaatagat ggttttgcag caagtttgaa cagccacgcc
     4741 gaagtgttga atatgttggt taatcctgtc ggaaccggga aagtaaccta ttactcgatt
     4801 tccgatttaa tgaatatgta agaaaggtgt ggaggaatga gtattttaga tcgtttgcgt
     4861 tcttttggcc gagcgaagcc gaaagcgagc aaacaagagt attttttgaa tgacccggga
     4921 ttgataccgt atttagtcgg aaaagatgaa atatcagaag ggattttttc cgtaattagc
     4981 cgtgtatcga acgtttttgc gtctctccct ctcaaaatga tagatgcgga gtttggccaa
     5041 ccggacgact gtcctgcata caacttgttg agcgaaggcc ctcgatattt tacaaagttt
     5101 gattttttcc gggacgtgga agttttgaga aactaccaag ggaatgcgta tgtgcagatt
     5161 ttccgaaata tcaatggaga agtagcagat atggcgttaa taaaacctgg tgcttgccat
     5221 ccagtgattg atatggatag cggggagctt tactaccaag taactgcgac tgacaaaggc
     5281 agttataagc aagttattta tgtacattac atggaaatgc tccactttaa acaaccgagg
     5341 tttggtggct tggaaggtac agaccccaca aaagtattaa cgaataccct cggatatgat
     5401 cgagaagtcc gaaaaatctc tttaagtcag cttaaaggag gtaatgaagg gctaaaagtt
     5461 aagtttgcta gcaatgtgga tgaagaagct aaaaaagcta cagttaaaaa cattgctgat
     5521 ttttatcgac aaaacggtgg actacttgtg gaagaaaacg gtgtagaaat cgaacgttta
     5581 caacgagagc tggtagacag caagctttta gatactgata aagtatctcg ctccagaatc
     5641 gcgatggtct acaacgtgcc ggaacatttc attgggagta accagtcgag ttactcttca
     5701 caggaacagc tcaatatgga gtttttgaca tacaatctag taccgaccgt taatcaatat
     5761 gaagcggaac taaataagaa aacactatcg agaaccgaaa aagcaaaagg ttatcgatat
     5821 aagtttaatg tcgcaagttt gctaagagct gacactcagg caagggggca attctatcaa
     5881 atcatgcgac gaggcggagc atactcagcg aatgatgtcc gaagatttga ggacttgcaa
     5941 ccgataaata aaaccggtat ggatgattat catatttccg gagacctata tccaatcgat
     6001 atggatccaa cattaagaaa aacaaactcg tctaaaagcg tagccgaaaa cggttaggct
     6061 tttttagttt gcaccgaagg gaggtgaaag gatgaaaaaa gtgacgttaa gcggcgatgt
     6121 cgtggataac gataccgcgt ggttatatga ctggtttggg attgattgta tctcaccagg
     6181 gaaaatttct gccgctctta cagaagcagc gggggatgaa gtagaacttg atatctcatc
     6241 taacggtggg gatgtcctag cggcaagcga aatatatacc gctatccgtg cctatccggg
     6301 aaaggtatcc ggaaatgttg tgagtattgc agcaagcgct gcaagtgtaa tcgcttgtgc
     6361 ttgcgaaccg cttagaatct cgccaacagc acacatcatg attcacaacg catgggtgac
     6421 cactagcggc aacgccgagg aattaaaagc caatgcggaa atgttaagca gtgtggatga
     6481 gtctatcgtt aatgcttacg agatcaagac aggactcgac cggaaaaagc ttgctgattt
     6541 aatggcaaaa gatacttggt taaacgcaca aacagcagtg gcggaaggtt ttgcggatga
     6601 aattatgttt gcagaagcac cagtaacggt actcaatgcc tctcaaccgg ttattccaaa
     6661 aaacgcggta actaagttga aaaatctaat actcaaagcg gaaacaccgc aagaagaaac
     6721 gctcttgcag aaaaaactaa aagccttaaa tggagggaaa aacgaatgaa tttagaacaa
     6781 ttaaaaaatg cgtgggtcga ggcgggaagt aaagtctctg atttaaacgc gcaactcaat
     6841 gcagcattgg ttgacgatga aaaaacagaa gaagatgtag taagtttgca agcacaagta
     6901 aaagcagcac gggctaaacg ggacggattg aaagagcaag tggcaaatat ggaagccgaa
     6961 caagtcttaa acgtcaaaaa agaaccatta gataaaaaag atgaaaactt gaaaaacaag
     7021 tttatcaaag actttaaagc gatggtcaat ggtgatcctg ctattatggc tactttgaca
     7081 tctaatacgg atgaatctgg taatgctatc ggattgacta ttcctgtaga tgtgcaaacg
     7141 actattcata ctttggttcg tcagtttgac tctttgcaag aatacgtaaa cgttgaaaaa
     7201 gtgaccacta ctagcggttc tcgggtttat gaaaaatggt ctgatattaa cccactgacc
     7261 gctttggata ctgaagacgg tgaaatccca gcaaatgatg atcctgcact ttacttgatc
     7321 aaatacttga tcaaacgcta cgcaggtatt tctacagtaa ctaacagctt gctaaaagat
     7381 actgccgaaa acattttggc atggttgtct aactggatcg cgaaaaaagt agttgttact
     7441 cgcaatacaa aaatcttggc agctattgat ggaatcaaag cagcgcaaaa gaaagatgtt
     7501 acagatgttg atgggattaa agatatcata aacgtccaac ttgatccagc tatcgaagct
     7561 acatctatgt ttattacaaa ccaagatggc ttcaatgttt tagataaagt gaaacgtgct
     7621 gatggatctt acttgttaca aaaagacgta gcttctgcaa ctggatatac cttcttaggt
     7681 aaaccaatca agaaaattgc ttctcgtttc ttgccaaaca aaggtacgca agctactcct
     7741 aaatatccac tgtatattgg tgatctgaaa gaagctgtta cattgtatga tcgcgaaaac
     7801 atgagcttgc tgacaacgaa tattggcggg ggggcttttg aaacagacac caccaaagta
     7861 cgggttatcg atcgatttga tgtgcagtta gtcgatgatg aagcagttgt tttagctaca
     7921 tttacatcta tcgcaaacga agtgccagta acaaacggtt aaggagctga tttcttatga
     7981 ttcttgatcc taaaatggat ttagacgaaa tcaaaaacgc actaaagatt gataccgatg
     8041 atgacgatgt ggaagtaaga cgtgcggtgc aagctgcaat tgcatacatt agaggggcta
     8101 tcgggaatga taagccctct ttttataagc aagaaaatga cacggttgat ctgattaatt
     8161 tagctattct gcaattagca gatcattatt acaacgctcg atcagcaacc gtgagtggga
     8221 acttgcgaga gtacgattta ggttttacaa gcctaatctt gcaactcaaa gcaagatatt
     8281 tgctttttgt ggaggagtag cgtatgcccc ttattcaaac aggaaattta aatcaacgca
     8341 tcaagtttgt ccgagatacg acggtcaagg acgaggacgg gcaagttgtc cggacttcta
     8401 caaccattct tacttgctgg gcaagtgtgc agacacaacg cctgaacgat attaagacgt
     8461 ccattggtac ggctttggaa ggaacactga cgttcattat ccgctatcaa caaaaatcag
     8521 agctaaccaa tgatatgaaa gtgcgttgga atggaaaaac gtttgaaatc attacgatta
     8581 cgaaaggcga gtttgcgaag gacttcacga caatcattgc aaaagaggtt tcaaaatgag
     8641 tgtagaagtc gatgcaaccg aagtgtacaa agcgcttagg gaagtaaaag caaacgttca
     8701 acgagtggaa agcccagcac ttagaaaagc tggggagtac gctcaagaaa agttacaaca
     8761 aaacacacct tactgggatg gaacgaagtc aaacggtaaa cgtggttcgt atatgcaaga
     8821 acatgctaag gaccatgtgg ttacaagctc ggtaaaaaac ggattgatag aagtcggcta
     8881 tgataaagat gtttcttggc ggatgcactt tatcgagttc ggaacaatca aacaacgtcc
     8941 aaaaggtttc gtacaaaaaa cacaaaagca aatcgaaaaa caagtaacac aaatcattgc
     9001 tgacgaagta aaaaggaggc taggactttg aaaacggcag tatcacaagt ctattcaatt
     9061 ctgaatagca atgaaaaaac aaagaacatt gatttttaca ccaatagtgt tccggaatcg
     9121 gctcaaacag tacctagcct tccagttggc agaattacag agatattcgg caactatgaa
     9181 gatttcgcaa gcaacaatcc tttgaccatt caatttaacg tacaggtaga tgtatgggta
     9241 tcgaccttaa aagaggttga tgccttttat tttgcccttg atgagattat gagggggaat
     9301 ggttggcaat gcgcatacac ggaacaaaca gatgatgagg atttagaagg tgcaaagcgg
     9361 attatcaaac gatatgtagc aaatatttca ctaaattaaa aggagagaaa atagatggca
     9421 acagtaggat ttgagagcgt catttttggc gtaaaaacag gtgcaggcgg cactctaaaa
     9481 gaattagtag cagataagtc gaaaggcgga gcgatcgaag ctaaaattac tggattaggc
     9541 gcaacttcta acacaacata cgcttcaaac gtaccattct tcattgcaag taaaggggtt
     9601 tcgtcgccaa aagttacgct tgacgtggca gacttaatgg ataacggcat ttacagcgaa
     9661 atcattggcg ctaaaaccgt ggatggtgta aatgtaattg gttcagaaac tgaagcgcct
     9721 tacgtgtcgg tagtcatggt tacagcgaac aaagaaggaa aacgcttatt catgggattg
     9781 gcaaaaggaa aattcagtca tccagatatc gacatgaaaa cagctgaaga caaaggagtt
     9841 gaattgcaaa ccgattctat cgaaggggaa ttcatttctg atgaacgtgg ctatgtatac
     9901 ttaacagccg tagaatcaga agaaatgacc ttacaaaaat tcaaggactt ggtaaataac
     9961 aaagcggggg agtagttaac cctgcatcta caccaacgac agatacaggg acaccaaaag
    10021 aaccagaacc aaaaattgat acacaaggtt agccattttt tggctagcct tatttttttg
    10081 taaaaacaag gaggaaaaca aatgattgaa ttgcaattga aacttgacgg aaagaaaaaa
    10141 acattcaaac aacaagatat ttccgcacgt gcaatgcgtg agtgtatcaa attttacgag
    10201 aaagcggaaa aagcagacct aactgattta gaagcaattg attcaatgat tgcaattaca
    10261 gcagatattt tccaagatcc agcagttaca tttgatgcta ttttagacgg tttgactgcg
    10321 agcgagttag taccggcatt agaaagtgtt tttgaacaaa tcaatgaact gggaaacaat
    10381 gaaaaaaagc agacggcgag caaaaagaga taagtttttc tgaagctagg aaagcaatgg
    10441 atcaaatcta caaagattta atcgaatcag gttggacgat gagagatgtg gacgaagccg
    10501 actatcatta tttgttacac ctttttggag aagtggagag tggcgaagaa tatgtagatg
    10561 gtgctgattt catcaaacaa tttttatcgg ctgaagactt ggtaaaactt gaggaaggag
    10621 gtaaataatg gcaggaaaag gacaaccggc aggaaatatc aagctaggga ttagtttaga
    10681 tagcactaat tttggtaaca cgctggacga aatcaatgcg aaagtcaaac aagctgagtc
    10741 gaatatgcgt gccaatctaa aggcttatga ttcagcagga cgttcatacg aagcacttag
    10801 tcaaaagacg aaagacttgt ctacggttat ggaagggcaa aacgccaaag taagagaatt
    10861 aacaaagcgc cgtgatgaag cgattagcaa gtatggcgag gaatcgaaac aagttgctaa
    10921 ccttaacaca cagataaaca atgctaccgc aaaatataat gcttacagtc gccagttgaa
    10981 tgacacaaaa aaagaattgg tgtattccaa aacagccgtc aatgatttat ctaacgaaat
    11041 caaagaaaat gaacgacaaa tgaacgccga agtaaaagcg ttgaaagccg ctggtgatga
    11101 atctggtgcg tttgaagcaa aacaaaaagg gctagccaaa caaacggaat tatccgagaa
    11161 agctatcgaa gaacagcgca aagttgtgaa actgatggct gatgagtttg gcgattcagc
    11221 aaatgaaacc gaagatgcaa aaagggcatt agaaaagtta gaacgacaaa gccaaatatc
    11281 tagcaggcaa ttagaagcac tcaaaagctc cagcgatcaa tcaggaaaaa aaatagaaga
    11341 ttttggcgac aagtccacaa ggtcagctag gaaactggat gggctaaaag acaaattagg
    11401 ctcgctaaaa agcgcatttt cgtttggtgc agttgctgga ttagcgcata acgctattag
    11461 cagtgtagta agtggcgtgc aaggcttggt tggcgaagca gtaaacgcat cggattcatt
    11521 gatgaagttt tccaaaacca tggagtttgc taactttggg aagtcacaga tagaaagctc
    11581 gaaaaaagaa atgaaagact acgccgataa gacggtttat ggtttagaag aaattctgaa
    11641 cacaaccgca caattggcat ctaacgggat tcctaactat acagaactaa ccaaggcggc
    11701 aggtaacttg aatgccgttg caggcggttc tagtgataca ttcaaatccg ttgccatgat
    11761 gctaacgcag acggcaggag ctgggaaact aacaactgaa aactggaatc aattagcaga
    11821 tgcgataccg ggcgcttcag ggctgttaca agacgctatg ttgaaaaacg gagcttatac
    11881 aggaaacttc cgtgatgcaa tggcgcaagg tcaaatcact tctgatgagt ttaaccaagc
    11941 gattgtacag ttaggtatga atgacggagc agttaaagca gctacttcca cagatacatt
    12001 gagtggttct tgggaacaga tgaaatctac tgtaataaat gggttacaaa gtatcataga
    12061 caaagtaggc gttgaaaata tcactggttt catcaacaga gtaacaaaag ggattgaaaa
    12121 ttctattcct aaaattactc aatttatagg ttggttgaga gatattggaa cgtggatcgt
    12181 tgaaaataga gagccactaa catggattgt cggaatcata ggcggaatta cattagcagt
    12241 aaaagcattg aacgtagcaa gtatgttgct ggcaattact ggcggaacat tggcagcccc
    12301 ttttgtggcg attggtgtag cattaggcgc actagcaggt gctttggtga tagcttatac
    12361 aaaatctgaa acatttagaa atatagtcaa tgcggctttt acagctgtga aaaacgtagt
    12421 tatgagcgtt atcaataatt tggtggaata ctacaaaatg ttgtggagcg tgttgcagtg
    12481 gctttgggaa aaaataaaag aatgggcttc atggattggc aataaattca ttgaaatgaa
    12541 gaacagcgtt gtgaatacgg ttcagaacct atggaatggt gtgaaaaact tcttcagtaa
    12601 tggcgttgga gacacttgga ataaggtagt tggctgggta aaaaacattt tcaacaaagc
    12661 aactgaattg aagaacaaag tttctgatgc aattggtaac ctgtggaacg gtatcaaaga
    12721 cacattccgt agaggcattg atacggtatt caattggttt tcagaactac cgacgaagat
    12781 gaagaatgcc attattggcg gtaaaaatgc cattgttgat gcgttcaaaa gtattttcaa
    12841 cgcagcactt aaagcgatag gtaaaccagt taacgcaatc atccatggag cttcatgggt
    12901 actagaaaaa ctgggtgctg acaaactcga agaatggaaa gtgccacaat acgcaaaagg
    12961 aacaccaaac ggaggtcatc cgggcgggcc tatgatggta aatgacggta gaggtgctga
    13021 agcggtaatc acacctaacg gacaagcatt tatcccacga gggcgaaatg tagtgttgaa
    13081 tgcaccaaaa ggcacacacg ttctaacagc tgaagaaaca gcttatatga ctggaaacaa
    13141 agcaccaaga tatagatacg ccaaaggtac aggctttttc ggaaatctat ggaacaacgt
    13201 caaaggattt gctggagatg ttggaaacaa gctgaaagat gtagtcggcg atgtatggga
    13261 ttttgtaaca gacccgggag cgttggctag gaaagtgtta aatggtcttg gcgtactgga
    13321 agggcttgtc aaatatcctt tagatgttgg taaaggtatt ctaagcaagg ctaccgaagc
    13381 attgacgaac aaaatcacag aactattcag cagtggcagt ttagacactt caatgggcat
    13441 gcaaggcgtt tacaaatact tggcggacgt tgcagttgca gtaatgaaga agtttccagg
    13501 ctttgtggca actagtgggt atagaccagg tgacccctat tcgcatggta aacgtaatgc
    13561 cattgatatt gcactacctg gtgtcacagg aggctcgcca cgctacacag aagcagccaa
    13621 ttacgcattt gagaagtttg caaacaaaat cggctatgtt atcacaaatg gcaaggttcg
    13681 tgaccgttca ggacaatcag gtacaggtat tcacaatgat tggagaccat ggcccgatgg
    13741 agatcactat gatcatgtgc atttaaacgg tgtgaaagac ccacaaaaca ctcaaatttc
    13801 aggagatagc gtgggaggca gtggggtaga aagatggcgc aatgtagcaa ttagagcgtt
    13861 gaaaatgacc ggtcaataca gtactgcaaa cttaaatgca ttactaaatc aaatgcgtac
    13921 agagtcaaat ggtaatccta atgcagttaa caattgggat attaacgcca aaaatggaac
    13981 accatcaaaa gggttgctcc aagtgattga cccaacattc agacagtatg caatgccagg
    14041 attcaacagc aatatttttg acccactatc taacatctta gcttcaatca gatacgcact
    14101 atcaagatat ggctcactaa caaatgccta tcgtggagtt ggttacgcaa acggtggaat
    14161 tgtaaaccaa catcaaattg cggaaatcgc agaaggaaac aagccagaaa ttattattcc
    14221 tttagataag gctaaacgat caagagcgat gcaattattg tctatcgcaa tggacaaact
    14281 aggagtttct cctaaaactt atggaaatgc gacaactgtt tccagtgatt acgaaatcct
    14341 agaagccatt gaaaaacagg cggcaacaac gaatcagctg ttatcgttat tgctggcatt
    14401 tttcaaagga aatagccgaa ctgatagaga tttagcttta gatattcaga agatcttggt
    14461 taggaggatg tagatgcgaa ctgtattact gagaaataga ataaacgaag aaattgattt
    14521 gtctacggag gattattttg ctactgggtt gagtaatatg gggtttgaag taaaaaaaga
    14581 acatgtggga cagtggggga atttcagaga aagcagtgag aacgttgaaa tatctgaatt
    14641 tcagtcatct gtaatcattt ctgtgcatgg gtttcgagaa aaagaactgt acaattcact
    14701 tgtgcagttc ctatcggaag gtccgtttga actggaattt gcttttgacg gcgaaacaat
    14761 ggtaagaaga tgcagtctaa aatctttaag taagactgaa atcgatccga aaacatcgtt
    14821 actaacagac actttagaac tatatttcac atcaaactgg tattccgtaa aacgcgaaaa
    14881 attaattcag cgaccgaatg tagtgaaaac acgtggtaag gtttttccgt ataaaagatc
    14941 ttatatctac actcaaaact tgtgggagaa aaaaggtgta ttcaaattca ataataattc
    15001 tgtataccta acgaatagca aggaacggat gtccccgcta aaaattcgtg tgattgggaa
    15061 gtgttcaaat ccgtattggg aagtaatcca aaactcacaa atcatcgcaa cggatggata
    15121 cttcatagat atgactgaaa cacagactct agaagtatca agcctttttg aagatacaac
    15181 ggcgatttta aaagatattg caggggtaga atcttctgtc taccaacaac aggattatac
    15241 aaaaactaat tttgttcagg ccccgactgg agaattcagc attgtgtttc atgttggggg
    15301 ggcagacgta gagattgagt tatacgagga gcgtgatctg ttttgatttt agcagtcacg
    15361 ctttttcatc gtgatttaat gctttataac gaacatttat tctctaacag ttttgaattt
    15421 ggtgcggacg agatcaacga agaggctagt agctttacga tggataagta cgttcctgta
    15481 aaaacaggcg attttctact agcaaaatat attcctagtg gaaaatttgc atattttggt
    15541 gtaattacgt cgcaggaaga cgaaaaaatc agttgtaaaa gcttacttag tttagctgat
    15601 agtgagatac cgactgcacg tgtgtcagga gataactacg aagagcatat ccggcggttg
    15661 attgaatact atttgctgaa tgatccaacg aaacaactaa aagatatttt agacgtcaaa
    15721 gcagaaagtg cgacctctca ttcgtatcaa gctaccgata cgaataaaca caagttaagt
    15781 gcgtatattc tcaatggttt caaaaaatac aacgtaaaat ggtatttcaa gggaattcaa
    15841 aacagaaaaa tctatacagg catacgtgct gtaaatgaat caatttacat taaagacaat
    15901 tcttctgaat ttagcgattg ggatgtgttt gttcaggcgc cgggcgctgg aaacgagaac
    15961 aagctattaa tcgttgataa agcaatgaaa gatatagaga aaccgataat actgtcaaca
    16021 tggtatttgg acgaagaaaa caatttgaca caagatggat cgaaagaaaa tatcacgaaa
    16081 ccaactgtca atttggttaa tatctacgat caaaccgcag aagataaagc atcctacgaa
    16141 gatgtggcaa aatcagagtt gaaaggcaat acgtattcgc atgaaatcaa agtgaacgtt
    16201 gtaagaaatg caaaaaattt gaatgtcgaa acgattgaaa cagggatgtt tgccacgatt
    16261 tcttataaag gaaagatata caagtcggtt ttgacagctt ggcgaatatc aagtgataag
    16321 gagtttgtgg aattgacttt cggaaacata agaagtcgtt ttatggatta ttttgaagat
    16381 aatgggggat aaaaaatggt tagcaatgtg gatggatatc aatttgaaaa cgtgaaagta
    16441 agcgcagaaa atgatgctag actttatcac gttttatata atcggaaaaa tcaggttatt
    16501 gatggttacg atcagtctat gaatttatct tcaagcggat taacagtaaa agttgctgca
    16561 ggagcagcga ttattcaagg tcgtatggtc gttgttcgac aagaagaaag tataacagtt
    16621 ccagcaaact caagtggtta tatagcatta acagtggatt tgacacaaga agttatacct
    16681 ggatctattc ttccagaatc ggaagaatat gaatggacta ataatcaagt caagctagaa
    16741 tttataacaa aagttataaa aggtaattta aacaatggtg ataaggtcta taatttacca
    16801 ctatgctcag ttacttctac tggatcaact gtttcaatct caaagatatc ggatagttac
    16861 gagctgactc tctctaaagg agaaattttg tggagtggga ctgcgttaat gcatgatact
    16921 caaactgtcc aaccttcaaa aaaaatgtgg cagacagttt caggtttttt attagtatgg
    16981 ctcccatacg aaaacgggca agcaattggg gatagatatg taactacgcc tttttataaa
    17041 gagcgtgtaa cttttactaa tgttttagga gaaattgttt caggatttga tgactatcac
    17101 aaaaagtggt ttagtaaacg aataaactat aattcgaata ctaatatatt tacaggtgca
    17161 gcaagcaatg caagtggaga taacgcaaat atggtgctta ggtatatagt ttctttttag
    17221 ttaggaggta tggaagagtg gcaaatttag aaattaaatt atctgcaaat aagagacagc
    17281 cttatctacg tcaccgtgtt gttggtagag ttggtgatgg ggggctcaca acaatcaatg
    17341 tacaacttct tgaggaagat gaaattacac cttttgtaat taatctaaac ggtactttga
    17401 aatttgtggg cgaagtttca aacggtaact ataccgaggg agaaccagaa ataatcgatt
    17461 cgactaatgg gttaattagt tacacgttca ctaagtcaaa tttcagcacg agtcatcaat
    17521 tcaaacaagc atattttgaa tatgtagatc ctaacggcaa aaaagtaact tttcagaact
    17581 tcatcataga cgtgttagaa cgagtagata ttaattcgga gcaagcgaaa tactatattt
    17641 cttcattgga aaaattacag agtgaaatgc aaaccacttt caatcagttc attagtgata
    17701 aacaggtcca atacgatcaa atctactcga aatataacga attagtaaga ttgataaatg
    17761 aatcagataa gcaagtaaat gatcgtattg ataagacaaa tgatcgtatt gatcaaacca
    17821 atcagcaaat cggcgatctc ggcaagctga aaaagatgta cagtaacagc atcgacttcg
    17881 gggactatga ttatagtggg aatccgaacc ttagcgctaa acttaatgct tcaagttttt
    17941 ctttaggtac tggcgcaaca gtcgcggatg ataatgatga gattgtgttt accttagatg
    18001 gcacaaatca actatcgaag tacgctagca aagcgcaagt gccggtagca gaagggaaac
    18061 aatatacgat tagttgtgaa attatgttag aagatgggtt cactggcgac ccttcaggaa
    18121 tacgtctgca acacgcatat ttgccaggcg gggttgttgt tttacagaca gagacagtac
    18181 ctaaaaatga attgaatacg tggcagacgc ttatcggaac gcgaacggta aaatacacct
    18241 ctgacgtacc aaatgaatgg taccctttgt ttagagacat ccgaacactt aaaccgaccg
    18301 gtaaagttag actaagaaaa attaagattg aagaaggctc aacagccacc ccatatcagc
    18361 caaacttact tgatgaccct tactggctag gtaaagcgcc tttgggtgag aatattgcta
    18421 ataagtctgt tacgtttcca atcaaatcta gcgcctacag cctataccaa gctaacatgg
    18481 aagaagaatt tgttttaggt caaacctata caattaccat gaaggcaacc aaaccaccta
    18541 tccaaacgtt cattgtttac aacgaggata gtggagatta tagatatggt aacttagagc
    18601 cagtagaagg gttagttgat acatggggtc tgacttttac accgcagaag gttggagtta
    18661 actaccccaa acggttaact attatccagt atccccaatc aacaacaggt gcatgtcaaa
    18721 ttgactggct caagatcgaa aaaggcaata ctcgaacccc gaatattagt gagtataaat
    18781 atcgtggtac tggtatgcgt gattcaaaca atccaaaaga ttatgtttgg gatctagcac
    18841 cagaatatgt cgaagataat ttggccacag atattaaaat ttctgaaatt actggtaaag
    18901 caaacaatta taccgatggg aaagtatcgg agattaattc gcagttgact gcttcaatta
    18961 atgaagtaga caccacagct aaggatgctc aaacaaaagc gaatgctaat gcgactgcta
    19021 tagatgaatt agacaataag atcgatgaac gcattaatga tacagctact accacattaa
    19081 cagttacaaa cgggaatacc ggatcagcaa agctttatcg tgaaggaaaa acagtttcta
    19141 tatattttgt ggctttaaac ggaaaaagca gtggtggaaa tgattcaacg atactaacaa
    19201 ttccagaagg ctatcggcca ccaattagtt ttgagcaact ggttggctcg atagaccgtt
    19261 ctactttgaa cagtgctcag ttatctattg gtgcagatgg agccattaaa tggcgaagaa
    19321 actcaagtta tggatcggat tatacctttg caattactta cacgatttag aaaagcgtga
    19381 atcgatatga aggcagcata tagaccaatt gaaccttacg gattcgagca aatcattgtg
    19441 aatgatgaag aacatttacc ggaagaatgc acagaagtcg aaccaccgat tctaaattgg
    19501 aaaccgaaat tcaattactg ggagggaaat aaatgaaaaa catttggaaa tatggacgta
    19561 ctggcggaga gtacgcagga aaagtattgg acgacatgct tgtatccgtt ccttacacag
    19621 atcagccacc gcttgaagga attcgtgctg atggcgaacc gttaacaatc gctgatcaaa
    19681 tgtttgatcc taaattgaat caatggatta ttttagcgaa cgcactagat cacaacgatt
    19741 taaacaatct caaagcaatg tatgagtcgt tagaaaatga gaacggcgat ttaaaacaga
    19801 tcaatgccaa actcatgcta agcgatgtag caattaaaca ggaaaatact gcattgaaag
    19861 aaaaagcgga tagtttagca caaatcaatt caaaaatgat gcttgcttcg ttacaaaata
    19921 gcaaagacat ttcagaaatt aaagagcaac taaatccagc ttcaaaggga ggtgagtagt
    19981 atgtttagtt ttagcgatgt gaaaatgatg tatgattggg gctgttttac tgacgatcaa
    20041 gttcgactat tcgttccact atgcattaca gacgaagaag cagataaaat cattagcaaa
    20101 gaagaaagcg catcttaagt gatgcgtttt tatttaaggt aaaggagttg tcacatgatc
    20161 aatttagggg aatggggaac aatcgcagga tcaattactg cgattgtttc tttgatttta
    20221 ttagtaataa gaccagtcac tgcatctttc tcgaagatta ctgaaactct ttcaaaagta
    20281 agtcacaatt tagatttgct gactaaagat ttagaatcga gcaaatcaga tcgattgatg
    20341 attcatgaag aactaaagaa acacgatgaa agattagata cacatgcaga aaaattggta
    20401 gaacacacac aacaaattaa aactttattt agagaaaggt ctcggtaaaa aagaaaggag
    20461 ttaagaagaa atgattttac ccgataagta ttatcaagtc attaaatgga cagttttaac
    20521 agtattgcca gctttatctg tattagtagc cacattaggc aaagcatatg gatggaatgg
    20581 aacagatatg gcagttctga ctatcaatgc agcagcaaca tttttaggtg ttatcactgg
    20641 tgtgtcggct tataatttga aaaaatagga ggaaacaaat gaaaaagaaa attactatta
    20701 ctgcgatgag cctattaacg gctctttttt tattgccgat taatgggttt gcctatacga
    20761 ttaacaatga atttaattta ggtgtaaacg aaggtagttc tcaagtagca aataatcagt
    20821 acattttact gcatgaaacg gctaatgaaa cagcaacagg acgcaatgaa gcgcagtata
    20881 tgcaacgttc atggactagc gcttatactg cttatattgt gggagacggc ggaattgttt
    20941 atcaagtcgg tcaacctggt tatgtacagt acggtgctgg ttcgtatgct aatgcaaata
    21001 gtcctgtgca gattgagtta caacacacac atgataaagc aacgtttgag aaaaactaca
    21061 aggcatacgt tgaattagct agagattcag caatgaaata tggtattcca cttacactag
    21121 acacaccgta taatcaacca gggatcaaat cgcatttatg ggtaacacaa aatatttggg
    21181 gcgatcatac agatccttac ggttatcttt ctgaaatggg cgtaagtaaa gaaaaattag
    21241 cctatgattt ggctcatgga tttaccgatg aaaatccgac aacttcagat gataaaccag
    21301 tcattgatcc aactcgagca ggtgctgcaa atcctaccct gacagatgga acaaattacg
    21361 cccacattga tcagttcgga gaaatcgaaa acgcaaactt acatgtggct ggttggcaca
    21421 tcgctaacta taaatacgag tatatcttca ttatggatta caatactggg aaagaattag
    21481 ctcgagtaaa agctgatgga atatatagac cagatgtaaa tcaagcttat aatactttag
    21541 gaaatgttgg ctatcatgta tcttttaaca tgcgcaactt ccctaataag aaagtctatg
    21601 taatgatgcg ggcaacgaat gatccagaag ggaacactaa aggcggagca caagattttc
    21661 atgataaacg ctggtattta aatattccgc aacgataaaa atagcccctc gtttttgagg
    21721 ggaagtacat aatgcaaatt tgtccataac ttattgatta tcttgtaaaa atgcggtaat
    21781 ttaatagtta gtgagaagag gtgcttaatt atagttaaaa aagaggaaat agaagcagca
    21841 tgtaaccaag caaatgttag gtttattgga gaagctttat ctggatatcc taagtataaa
    21901 tacttacaca actggttaca aagtaaaagt ttttatctta ataaagaaag atgcatgcct
    21961 aataaaaatt atagggttta taaaagagga actattgtat atgttgattt tggggtgaac
    22021 gtgggttatg agttatctgg taatcatttt gctattgttt taaataataa agataattcg
    22081 aaaaatggtg ttgtatgtgt agtaccaatc tcttcaaaaa agaaaagtaa ttatgtatct
    22141 gtaggaaaaa tattagaagt tgctagtatt aaacaattta taagccaagc tgataaatta
    22201 aaagagaaac ttaggataat tattttactt tcattaaata gaggc
//
LOCUS       DAZAOD010000042        22175 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000042 DAZAOD010000000
VERSION     DAZAOD010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.043"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            240..2075
                     /gene="tdc"
                     /locus_tag="ACHDPO_001575"
     CDS             240..2075
                     /gene="tdc"
                     /locus_tag="ACHDPO_001575"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFN3369197.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2380..3858
                     /locus_tag="ACHDPO_001576"
     CDS             2380..3858
                     /locus_tag="ACHDPO_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFN3369198.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3824..5155
                     /locus_tag="ACHDPO_001577"
     CDS             3824..5155
                     /locus_tag="ACHDPO_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFN3369199.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5269..7821
                     /locus_tag="ACHDPO_001578"
     CDS             5269..7821
                     /locus_tag="ACHDPO_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFN3369200.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7828..9267)
                     /locus_tag="ACHDPO_001579"
     CDS             complement(7828..9267)
                     /locus_tag="ACHDPO_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3369201.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9242..9424
                     /locus_tag="ACHDPO_001580"
     CDS             9242..9424
                     /locus_tag="ACHDPO_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369202.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            9613..9975
                     /locus_tag="ACHDPO_001581"
     CDS             9613..9975
                     /locus_tag="ACHDPO_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFN3369203.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10162..11019)
                     /locus_tag="ACHDPO_001582"
     CDS             complement(10162..11019)
                     /locus_tag="ACHDPO_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFN3369204.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11139..12050
                     /locus_tag="ACHDPO_001583"
     CDS             11139..12050
                     /locus_tag="ACHDPO_001583"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFN3369205.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12057..13708
                     /gene="mdcA"
                     /locus_tag="ACHDPO_001584"
                     /pseudo
     CDS             12057..13708
                     /gene="mdcA"
                     /locus_tag="ACHDPO_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            13810..14109
                     /locus_tag="ACHDPO_001585"
     CDS             13810..14109
                     /locus_tag="ACHDPO_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFN3369206.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14099..15775
                     /gene="mdcD"
                     /locus_tag="ACHDPO_001586"
     CDS             14099..15775
                     /gene="mdcD"
                     /locus_tag="ACHDPO_001586"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFN3369207.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15779..16372
                     /locus_tag="ACHDPO_001587"
     CDS             15779..16372
                     /locus_tag="ACHDPO_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFN3369208.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16396..17472
                     /locus_tag="ACHDPO_001588"
     CDS             16396..17472
                     /locus_tag="ACHDPO_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFN3369209.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17497..18366
                     /gene="mdcB"
                     /locus_tag="ACHDPO_001589"
     CDS             17497..18366
                     /gene="mdcB"
                     /locus_tag="ACHDPO_001589"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFN3369210.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18477..19241
                     /locus_tag="ACHDPO_001590"
     CDS             18477..19241
                     /locus_tag="ACHDPO_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFN3369211.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19730..21823
                     /locus_tag="ACHDPO_001591"
     CDS             19730..21823
                     /locus_tag="ACHDPO_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFN3369212.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21848..22150
                     /locus_tag="ACHDPO_001592"
     CDS             21848..22150
                     /locus_tag="ACHDPO_001592"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3369213.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7179 a         3788 c         4725 g         6483 t
ORIGIN      
        1 tgtttgttcg ctttttttag gttatctatt ttagaagact gatttattga aaaattgttc
       61 gcttttttgc gttgaattat cagaaaaatc cgactttatt tatttttgtt tgtaaaaatc
      121 tacgtggatt tgatgttata aaaaaaaaat tctcattttt ggcgctatag tgaagaggtg
      181 ttacagataa acacatgtat ctgcaagaca ttgaccaaca aaatatggag ggaagaaaaa
      241 tgaaagatat ggatatcaag gccgtcttta taggcgacaa agctgaaaat ggaccagttt
      301 ataaaatgtt gttgaacaag atggtagatg aacatcttgg atggagagaa aattatattc
      361 cttcagatat gcctgcaatt agcgaaggag ataagctcac tccagattat ctagccaccc
      421 gcgaccatat gatagaggtc ttggatgaag tcagtcagcg attacgcgca ggatcgatcc
      481 catggcattc agcaggccgt tactggggac aaatgaatgc tgaaacattg atgcctgctt
      541 tattagctta caactatgcg atgctgtgga acccaaataa tgttgcattg gaatcttcta
      601 tggcaacttc gcaaatggaa gcagaagtag gacaggattt tgcttcatta ttcaatatga
      661 cagacggatg gggacacatt gcagcagatg gttctattgc taatcttgaa ggattatggt
      721 acgcccgttg catcaaatcg attcctttag ctgtcaagga agtgctgcct gaaaaagtga
      781 aaaaaatgtc tgagtgggaa cttttgaatt tatctgttga agaaattttg gaaatgaccg
      841 aaagctttac ggacgaagaa atggatgagg tcaaagcagc ttcttcccgt agcggaaaaa
      901 atatccaaag attagggaaa tggctggtcc ctcaaacaaa acactattct tggatgaagg
      961 cgttagatat ttgcggagtc ggcttagatc agatggttgc tatcccagtt caagaggatt
     1021 atcgaatgga tattaatgct ttggaaaaaa caattcgtga attagctgga caaaaaatcc
     1081 caattctagg tgtggttgct gtcgtaggaa cgacagaaga aggtcaagta gacagtgtag
     1141 ataaaatcgt ccaattaaga gaaaggttaa aagatgaagg gatctatttc tatttacatg
     1201 ttgatgccgc atatggcggc tatgcgcgtt cactgtttct aaacgaagca ggagaatttg
     1261 tgccgtatgc ttccttagct gaattctttg aagaacatca tgttttccac cactgcgtaa
     1321 cgattgacaa agaggtatat gaagggttca gagctatttc agaagcggat tctgtcacga
     1381 tagatcctca taagatgggc tatgtccctt atgctgctgg aggaatcgta atcaaacata
     1441 aaaatatgag aaatatcatt tcttatttcg cgccatatgt gtttgaaaaa tcagtaaagg
     1501 ctccagatat gttaggagct tatattttgg aaggatcaaa agctggagca accgccgccg
     1561 cagtctggac agcacatcgt gtattgccat tgaatgtgac cggatatggt caattgattg
     1621 gggcttcaat cgaggcagct caaagattca gagaatttct cgatcatctg acttttactg
     1681 ttaaaggaaa aacaatcgaa gtctatccat tgaatcatcc tgattttaat atggtcaatt
     1741 gggtattcaa agaacaaggc tgtacagatt tgaacgctat caatgaatta aatgaaaaaa
     1801 tgttcgatcg gtcttcttat atggatggcg atgtttatgg tgaacggttt attacttctc
     1861 atactacatt tacacaagaa gattacggtg attctccgat tcgttttgtt gaaagaatgg
     1921 gtctaacgaa agaagaatgg aaaaaagaac agaaaatcac tctgctacgt gcggctatca
     1981 tgactcctta tttgaatgat gatcgaattt tcaattttta tacaaaaaaa atcgccaaag
     2041 caatggaaaa gaaactaaac gaaatcatcc aatagaactg atttttgtgt gaaagaataa
     2101 caagagacat atggagaaca gacaattatt tgcttcatca aaacaattgt atttccccct
     2161 gtttttcata tattcctcgc caagatattc ttttttataa aacgttctat aagttggatc
     2221 gttcgtttca tgtatcaaac ccagttcact aagatcgttc aatggatgtt tcggtgatac
     2281 tgggttttgt actgaatcga tgaaaccttg tcatttctgt tcttgaacaa aaataaaaga
     2341 aaacaaaaac atatgtcgct attgaaagaa ggaataaaga tgaaagatac tggttcatca
     2401 aagcaaatca cgaccatgac ctttatcgga atgacctgcg cccttgtagc aagtgtacga
     2461 aatattccag atgtagcagc aacgagctgg acgatgattt tttacatgct ggttgcagta
     2521 ttattgtacg cttttccaat ctcattgatc tctggtgaat ttgctggaat gtttccccaa
     2581 aaaggtggtc cagaactttg ggtatcgaat gctctaggaa aaaaatgggg gttcgttgtc
     2641 tcatggctgt tatgggtcca aatgtttcct gggatggtga tggtcgcttc agcactcgct
     2701 ccgttgtttg gtaatattat cgataatgtg ccgcttggtt tgaacagcaa atttacatta
     2761 gttgtcattt tagtcgttta ttggatcatc acttttttga atttgaaatt tgatatggca
     2821 aaaatcggcg gaaaagtcgg tgtttggtta ggattgtacg tgcctttgac gatgatgctc
     2881 ttattagggt ttgctgcgtg gatcaaagtt gggatcgtac caaccggaac attaggcagt
     2941 ttttcatggg acaaattaat accagatact acgactgcat cctcatttgt ttattttgcg
     3001 ccgatcatgt ttatttttac tggtatcgaa atgtcctctg tgtatatcac tcgattggaa
     3061 aatccagtta aaacgtatat tcgcggagta tttgccgcgt taatttttat atttttcgtc
     3121 aatattttga atgctttagt tgtagcaaat gtcgtaccaa aaggacaaat ggaattgaat
     3181 aatatcgcgc aatctatttc gatttattgc caaattcttg gtttgccaca tcttattgtg
     3241 aatctgttta gtttacttgt cttcattggt gtagcagtcc aattatctgc ttgggcctca
     3301 ggaccagcaa agacagtgac agaaagtgct agaaaaggtg cgtatccacc aaaattcaat
     3361 ttttggaaga cgaatcaatt tgacgtatcc aaatccgtta ttttgactca gtctgtcatt
     3421 atctcaatct ttgcactttt ttatttgctg attcctggcg tcaatcaagc atttttgatg
     3481 ctcgtaaatt caactactgt tatctactgt atcgtctatg tcatcatggg gatcgcagtt
     3541 ttgagattgc gttatacaca tgcaaagttg aatcgaccat ttagaattgg aaaaaaagag
     3601 aaaaagagca atcttggagt ttggactgtc gttattgttt tatttgcggc aatcggattt
     3661 tctgtcggac tgacgatgaa agctggaaca tggatcaatc taattgcagt cacagccatc
     3721 agtgtcattt tgtttgtagt accactctgt attgaaaaaa taaagaaacc ttcttgggaa
     3781 caggaagtcg ccatgctgct tgaaaaagaa aaaggtgaac ttgatggaaa aaccggcaat
     3841 gaaacggact ctaactaatc gaaatatcca gttaatcgca ttaggtggcg caattggaac
     3901 aggattattt ttaggttcag caaaggcaat tgcatcagca gggccagctg ttattctcgt
     3961 ttatttgata tgcggtttgg ctatttatgg tttgatgcgg gccatgggtg atttattttt
     4021 agcaaatagt acatttaact ctatcagtga tttcgttgac tattatttag gcaaaaagtg
     4081 ggcatttttt gtcaattgga cttattggct ttgctggctt ggagctggac ttgcggaatt
     4141 aacagcaata ggattgtata tccatttctg gtttgtacat gtaccagctt tgataagcgg
     4201 aggtagcgca ctaatgatct taatggcagt caaccttgtt gcagtcaagt ggtttggtga
     4261 attggaatct tttttctcaa tcatcaagat cttggggatt ttccttttta tcttattggg
     4321 tataggattg agtgtctcag attttcatac ccagtctatc ggaatcaaag aaaattttgg
     4381 acagatcgat gaattactac cgtttggctt tgctggaatg gtagtctcat ttcctatggt
     4441 tttattcagt tttgctggaa ttgaaatgat cggcttaacc gttggcgaga caagtgatcc
     4501 gcaaaagaat ttgaaaaaag caatcaactg tctgccttgg cgtattctct ttttctatat
     4561 aggaacgatt ttgtcgattt tatttgttgt tccatggcat tgtttagatt taaaagaaag
     4621 tcctttagtg actatgctgc aagtgatcca ttgccaaggc ggagcagcaa ttgtcaatct
     4681 aatgattttg gttgcttctt tgtcctcagc aaatagtgca gtctacagta ctagcaggat
     4741 tttatatcaa acagcaaaag aaaaaagttt gccccattgg ttttgtgcgc tttctaagaa
     4801 aggcgtacct ttacacggta ttttaattac aggaatgtta ttttttgccg gtctttgtct
     4861 acattttttt gtagctgata gtcgattgtt ttttcagctt ttggcaggca tgacaacgag
     4921 ttgttttcta tttgtgtggt cttcgatctt gtgtgcacat gttcaattta ttaaagaaaa
     4981 gaaacggaac actacacaaa gatataaaga tcttgctttg ttggtgtttt ttacttcaat
     5041 tgctttcagc ttgttattcg aaagcacgac acgctttatt ccttttttat tggttatctg
     5101 gtttgtattc ttaaattttg tatataaaag aataagcaat agaaatatca gttaggccca
     5161 gatacatttt gcaaaacgaa ttatttcaga cccccctgaa ataatcgata cgcctgaaaa
     5221 aacttccctg cgtataataa cagtatcaat taaacaggag gggataggat gaactggtac
     5281 agattgacgg tagaagatgt attgaaaaac tatcaaacat caacagaagg cttgtcgcaa
     5341 gaagaacgac agaaacgcct gactgatcaa ggatataatg aaataaaagc aaggcagcag
     5401 acaaaacgat ggaaaaaaat agcaaagcat tttactgatc tgctgatgat cgtgttgatc
     5461 attgcctctt ttttgaaatt tgcttctagt gaatatattg aaggaagtat tattttattc
     5521 gtagtgatcg tcaatggact cgttagttac tggcaagaaa gaaaagcgga agaatcattg
     5581 aatggtttga agcagctgat gggacaagaa gcgatagtac tatcaaacgg gatgcaagaa
     5641 aaaatccctg cgaaagaact ggtaaaagga gatgtcattg tcttacgtgc cggagatgtc
     5701 gttccagcag atatccgatt aatcgaagca catgatttat tagtggaaga atcgattttg
     5761 acgggagaat cagaagcatc tgaaaaaagt catgccgttt tgacagaaga agaatcgatc
     5821 ggcgaccaga aaaatatggg tttttcagga acgcttgtac aatctggttc tgcagtcggt
     5881 gtcgttgtag aaacaggaaa cacgacagaa atcggtaaaa tcaatcaagc attgcaatcg
     5941 gtcgaacaac aaacgacgcc tctgattaaa aaaatcaacc gattaaacaa acaaattttt
     6001 caaggcattc tttgtttgag cctattctta gttattttta cgacatttcg atatggtatg
     6061 gattggcata tccttctttc ggctacgatt gctttggtgg tgtcaatggt acccgaagga
     6121 ttgccagctg ttttgaccat gattctatcc gttggagtac atgaaatggc aaaagaaaag
     6181 gcgatcatca aaggacttcc ttcggtagaa acattaggtt ctatgacagt gatctgttca
     6241 gataagacag gaacattgac aaaaaatgaa atgacagttg tggatgtagc tgcaaaagaa
     6301 gaagcctgcg tgttgtccat tatgaaaaac tgtcaggaat taaaaacaaa agaagaacag
     6361 aaaacagaaa atttaagtgg caatccgaca gaagttgcgc tgattcgaca cacagaaaca
     6421 gccaatctac ctttgaaaaa aatagaagca aagattccgt tcagttctga atacaaatat
     6481 atggcaacga tgcatgcgga ggaaaaagga gcggtgattt acgtcaaagg tgcaccagaa
     6541 gtattatttg ctaaatcaac tctttcttct gcagaacaag aagcatggag tcagacagct
     6601 gcagaatttg cgagaaaagg tcagcgtgtt ttaggatttg cttataaaaa agtagattcg
     6661 aaacaggaac tcacgcatga gactttaacc caattaactt ttgcagggat cgccggattg
     6721 atcgatccgc caaaagaaag tgcagtcaaa gctgtaaagg aatgccaaca agcagggatc
     6781 tcagtgaaaa tgattacagg ggatcacaaa gacacagcaa aagcgattgc ggaacaaatt
     6841 ggcttaaaac atactgccaa agttttagaa gggatcgatt tggatcttat gtctgatgaa
     6901 gagttgattc agcaagtgcc aatagtcgat gtctttgctc gaacgacacc agaacataaa
     6961 ctgcgaattg ttaaagcttt gcagaaaaat ggagaaatcg tcggaatgac cggagacggc
     7021 gtaaatgatg cacctgcttt gaaaagatcc gatgtaggaa ttgctatggg aatcaaaggt
     7081 agtgaagtaa gcaaacaggc agctgatatg gttttaggag atgataattt ccatacgatt
     7141 gcaaaagccg taaaagaggg ccggcggatt ttggataatt tgcaaaaaac catcaatttc
     7201 ttcttgccaa ctgcattagc tcaaggattg atcttgattt gggcacttat gctgaatcgc
     7261 ccgctacctt tgtccccagt acagatttta tgggtcaata tggtaacgac aatcacttta
     7321 tcttatgcac tagggttcga gtcgccagat ccagaaatca tgaagcgccc accaagagat
     7381 ccaaagcaag gaatcctatc tggttatcat ttgtttcgga tcatctatgt ctccctactg
     7441 atcatggttc ctgcctattt attggctatg cagtttgaag ggcaaagctt acagcaaacc
     7501 attcttctgc aaaatatcgt cttagctcaa gctgtttaca tgatcaattg cagagagttg
     7561 tccaagccgt cattgaacca aggtcttttg caaaacaaag cgctttttct ttcattaggt
     7621 atccttgctt tattgcaagg gatggttatt tttctaccag tcggccagca gctgatcggt
     7681 acagtaagtt taacgatgac acaacagtta ttgattggag caaatgtgat tcttctattc
     7741 ttagttgtag aaatagaaaa agggatcatg aacaaactgt ttcgcaaaaa agaaaaaaca
     7801 gctagagaat acagtcgcta gccgttacta taaaaaagtt ttgaaagtga gttcagtcaa
     7861 acgattgagc tcatttttcg ttggaataga agaaatgtat acaataggga tatctagaga
     7921 atctagaggg aaattggaaa tcaagatatc tgttttttca aaagaaatag tggaaagatc
     7981 ggttagttcg ataggtaaga agcagacacg ttttcctaag taatctttta attcctgctg
     8041 caagaacgcc ttccatgaag gttctccttg gaaaataaaa tagacattga acaaattcgg
     8101 tttgatagaa aaaatcgttt gttggatcag tagagacaag agttggagaa agtaatttgg
     8161 ttcattgatt tctatttctt tttttagatc gttcagtaaa ttctctttct gttgatacaa
     8221 gtgtgcatat tgctgatcat atgtttctaa aaaacgatgg tattgacggt ccaatgcttc
     8281 aatcaatatc ggcgattcat gatattttaa tatgaggaga gccaagttat cagtcagaga
     8341 tgtttttttt agttgatcaa gagacagctc tgaagctagt tcctctacaa acgtttcgag
     8401 gacctctaaa aatggagaat gatgcaggca gcgagcggtt tcttgtccat agttattgtt
     8461 gtaattccaa ctttccagaa agcagaaaga agcaaaagaa agctcagtgt ctttaagata
     8521 aataccttcc gttaaataca attttttcaa tgcagagtca tacagggagg agagtgtgct
     8581 gttggtatgg atagaagaat ctaatcggca attcgctttt atacggatcg tattgataaa
     8641 gaaccaacat gttccgaaaa tctcttctgt ttcaaccgct agttcagttt gactgaggtt
     8701 tcttaaaaat tgaaaataat gggattcatg gatcgaataa tcctcgaaaa aatagttgtt
     8761 atgagtgaaa ggaatcagca atcgatgata aaaagtacga atcgcacgct cttttccaag
     8821 aatacaagct gtatatttcg tcaaatcgat ctgcaagtcg taacttgcta aacgctgatt
     8881 gattttagtc acatgtcttt tcaatgtccc ataagaaagc ccatggtcgg ctagaaaatc
     8941 agggacagca actttttttg taaaaagcag atttttcagc agttcgacac tgactgattg
     9001 tttgaaaaaa atctcccaaa ggtcatttgt taataaattt tgctggtttt gcaaactgat
     9061 tcctgcttga tcgctgatga tgtcccagcc ttcgggcagc tgagagcgaa tagattgaag
     9121 gtcagaaaaa atcgttcgtt cggttgtccc tatgatttca gctaattcat ttacggttat
     9181 ctttgtatga ttcagcaatt gttctactaa agaaacatga cgtcgaatat ctttttcggt
     9241 aatgattttt ttcattagtg aatacatcaa tcagactccc ttctattcta agaatacgga
     9301 gaaaataaac ggtggtcaag tttcaactga tttttcaatc attgtttatt tttctggagc
     9361 atttactgat gataagaatt tcatcatgaa cttgaaaaat gataccacta aaatcaaaaa
     9421 ataggtgggc aaacaataat aaacatttta atagtagatg gtagcaagac caacacaggc
     9481 ggattgaaca tttaagagtt gataaaaaag aaaaatatcg aagtatttga ttagcaacta
     9541 cttgtattca tttttctatt cttacgtggt atctttgaat aaagcgaatc aataagaaag
     9601 agatggaagc agatgctaac gaaaaaagaa ctaatcgatc acatcaatga aacatacaat
     9661 ttgtctccag aatatatttt taaaaaattt cctgattatt gcgtattcag acatcaaaaa
     9721 agcaaaaaat ggtttggggt cctgatgtct gttccagaag aaaaaatcta tgatgatgca
     9781 agtgaccata ggatcatcaa tattcttgat ttgaaggtcg atcctgaact tggcggaatt
     9841 ttgcgaggaa aagaggggta ttttccagcc tatcacatga ataaagaaca ttggatctct
     9901 attgatctac gtaaaataga aaagctagat gaactagcag atttgattga tggaagtttt
     9961 aaatcaacgc aatgaatgtc taggacaata gagaagaggt tgtgacagaa atgtttagct
    10021 tcaagaaata agaaggaatt tacgaaaatt gcttctcaaa tttttgggaa atttcggctt
    10081 attttctaag aaattacttc tggaacaccg tttgttcgaa aaaagagctg cgacaagaat
    10141 tttgtcccag ctcttttttt tttattttcc taaataaaat tcccgcatcg tttttgcaat
    10201 cattttgatc aaaggatgat cttctgtgaa gctagaagat aaataaattg ttcgtgtcaa
    10261 gggcaaatct ttgatttccc gcaagacgaa aggatcattt ttatcgtaag accaagaaac
    10321 ttttgggaaa aagctaacag ctaatccttg cttgacaata gaacgtaatg tcgcaggatc
    10381 atctgtcgtc gaactgatcg tcaattcgat acttttcgct tcaagtgctg catccagtgt
    10441 atgacggaag gcgttgctct ttgacagcat caagatgggg gtgcgttgga tatcttctaa
    10501 ttgcagatgt tcttttttag caagaggatg tttcttagga atggcgacat aaacaggttc
    10561 tttcatgata ggaatattgg tcatgccagg cttcatctcc gaagtgatgt acagtacagg
    10621 atcggtaata tcatctggta aatgatgttg catgatcgtt aattggatat caggatgctt
    10681 ttccataaaa attcggacca agttcggaat agaaacagag gctacctcta aatacaatat
    10741 gacggaagta acgatcttct cattgaccga agacaataat ttgattcctt cttctaatgt
    10801 gtctaatgtc ttgactgcat atggataaaa ttcttctgca taaacggtcg tctcaatgtt
    10861 tctgccgcta tggtaaaaca aagggacacc taattcgttt tccaaatgtt tgatcgcacg
    10921 gctcaaggca ggttgagaaa taaataattc tttggctgct tgggtaacat tttttgtttc
    10981 gaatactttt ttaaaatact gcagatgaag caatttcata attatccatc ccatccatac
    11041 ctttttgtta tggttttttc tttttttggc attttttatt atagcagaaa ttgactaaga
    11101 tagcagtgga aaaagtaagt gctgaggagg cgaggctcat gagtacaggt ttcttatttc
    11161 ctggacaagg cagtcagaag ttagggatgt tagcggatat ccctgaaatg tacatggaac
    11221 gtttagaaaa tgtgacgggg tatcggttag ttgataaaga agaaaactat caagatacgg
    11281 tttttatcca gctagcatta ctgacaaaag cagtatttta tttagatgaa atggaaaaaa
    11341 acggtattca gcctgatatt gcagcaggac attcgattgg tgctttttgt gcagctgttg
    11401 cttgtcgatc tttgagattt gagaatgcag cggaactagt ctatcaccgc gcagtcttaa
    11461 tgaaagaagc ttatccaagc ggttatgcaa tgggcgtagt agtaggtgtg acgagaagcg
    11521 aagctgagga aattgtagca aaaacatttg atcctgacca tccagtttat ctgtcaaatg
    11581 aaaattgtcc gatgcaacat acgttatctg ggagtatcga aggtttatcc gttacgttgg
    11641 cagaagccaa acggcaccaa gcgcaaacag cgaagctgct gaaagtccct gtgccatctc
    11701 actgtctctt gatgaatgat acggtcaaga aattcaagcc gtatatgcag tctgtccatc
    11761 tatctgatgc tagatgtttg tatataaaaa atacggatgg aagagccact caggacgcag
    11821 aagagattcg taaagatttg ttggaaaacc tagctttccc tgtgcagtgg aaccaaatga
    11881 tggacttggc aaaagaatta ggaatggatc tgacgattga atttcccccc ggcaatactt
    11941 tgacaaagct gattcataca aaatttggtg tagataaagg gatccgtacg atcaatctag
    12001 accaacatgg tattgatgac gccacgtttc tatatcaaaa atggagatga ctaattatgg
    12061 aaaaaccaaa ccgcaactgg gcttctaaac gcgaaaaaaa agcgcagcga ttggaaaaaa
    12121 tcagcaactt gctcaatggc aagtatgtag aaactgaaaa aatcgtagaa gtaatggaaa
    12181 aactgattgc tcccggcgac aaagttgtat tagaaggcga caatcaaaaa caagcaagtt
    12241 ttctttcaga aagtcttgaa aaagtagatg cagaaaaagt gaatgatctg catttgatca
    12301 tgtctagtat ctcacgacca gaacatttga atatttttga aaaaggaatc gcaagcaaga
    12361 tcgatttctc ttatgctggt gcacaaagct tgcgtgtcgc ccaaatgatt gaagacggca
    12421 caatgaaatt aggtgatatc catacttatt tggaacttta tggacgctta ttcatcgatt
    12481 tgattccaaa tgttgtttta gtagctgcag ataaagcaga taaagacggc aacttgtaca
    12541 caggtttcaa tacggaagaa acaccaacaa tcatcgaagc tgcagctttc aaagatggta
    12601 tcgtgatcgt tcaagttaac gaagttgtcg attctttacc acgtgtagat atccctggtg
    12661 actgggtaga cgttgtcgtg aaagcagata aaccttatca attagaagct ttattcacac
    12721 gagatcctca aaacatcaca gaattgcaaa ttctaatggc aatgatggca atcaaaggaa
    12781 tctacgcaga acacggcgta caatctttga atcacggtat tggattcaat acagcagcta
    12841 tcgaattgtt actgccaact tatggtgaat cactagggtt aaaagggaaa atcgcgaaga
    12901 actgggtatt gaacccacat ccaacgatga ttccagccat cgaatcaggt tgggttgaaa
    12961 gcatccatag ttttggtggc gaagttggta tggaaaaata tattgctgct cgcccagatg
    13021 tcttttttgt cggtaaagac ggcacgatgc gcagtaaccg aacattatca caagctgcag
    13081 gacaatatgc catcgatatg tttatcggtt caaccttgca attagattac gaaggaaact
    13141 cttctaccgt aacaaaagga cgtttatctg gttttggcgg tgcgcctaac atgggacata
    13201 atcctggcgg tcgtcgtcat tctacaccag catggcaatc acttcgcgac aatgatgatc
    13261 cattagggaa aggccaaaaa ttagttgttc aaatggttga aacatatggt tcaaataaaa
    13321 aaccagtctt tgtcgaagaa ttagatgcac tagctgttca aaaacaagca ggcttagcca
    13381 atgcaatgca ccagtgatga tttatagcga agatactaca catatcgtga cagaagaagg
    13441 aattgcttat ttgtacaaag caaaaacaaa agaagaacga caagcagcaa ttgcagcaat
    13501 tggcggtgtt acacctcttg gaatgactag cacgaaagaa tcactagata gcttgcgtgc
    13561 agccggcatc gtgaaattac cagaagatct aggcatcaaa cgtagtgaag cgaaacgttc
    13621 attattagct gcacaaacca tcgatgattt gatcgaatgg tcagatggcc tgtatgaacc
    13681 accaatgaaa ttcagaactt ggtcataaaa ttggcgagaa aaaccttttg tcgccattta
    13741 cccagatgga agaagaaaga cgaataagca gaacgtgtat gctctgtttt acaaaaaggg
    13801 gagagatcca tggaacaatt agcttataaa tatccaacga aacagccgat caataagaaa
    13861 atccatgtag gagtggtcgg ttcaggagat ttggaaatct tgatgtttcc aacagaaaaa
    13921 acagaatcta ctgtaaaaat ttgtacagga agcgatggct tcggcgaagt atggaacaat
    13981 gtattaacga gattttttga tcgttatcca atttcagcag atatcgtgat caatgacttc
    14041 ggtgctacac caggagttgt gtacctacga ttgacgcaag caatggagga actttcagat
    14101 gaaaaatagt tttgtagaat taaacgccag agaacgagtg aacgctctac ttgacaatgg
    14161 acgtgaattg attgatccat tcgatcaaat catcgcgcca agtttaccag cacaaggaat
    14221 cgtccctgaa agtgatgacg ggatcgttgt cagccgtggc acgatcaatg gcaaacaagc
    14281 agtagtaatc gctatggaag gaaaattcca aggtggcggt atcggtgaag tttccggtgc
    14341 aaaaatcgtt gctgcacttg aacatgtgtt agaagaaaat aaaaaaggaa atgagatctt
    14401 tccagtcatt gtactagata caggtggtgt tcgtttgcaa gaagcaaact acggactgtt
    14461 atctatttca gaaatcggaa atgtaatcat tgctctaaaa caatatgtac cagtcatcgg
    14521 tttgattcca ggacgtgtag gatcatttgg cggtatgtcg attacttcag cattaatgag
    14581 ttatttaatc gcaacaaaaa aagcgagagt cggtttgaat ggaccagaag ttattgaaca
    14641 agaagcaggc gttcgagaat ttgattctag tgacaaagac ttgatttgga atacattagg
    14701 atctcgtcaa cgggtagaat caaaaatcat tgatgaatta gtgactgata gtgtagaagc
    14761 aatcaaagct gctgtcatcg cagcaatgga cgaacgaaaa gacacgcatc gcagtgaaag
    14821 ctcagcattt tatttatcat tacttgattc tttagatctt tcaaaaccaa tggccattga
    14881 cgattacaat gaagcaattg ctaaccatca agcaaaatca attgacttac cagaagtagc
    14941 agaaggaaat gaaccagctg cagcaagtgt tggttacgat tggtttgcgg cactaactgg
    15001 catgaaaaat ccaacttctt ctattagtac tgtgtattat ggtaaatcaa gtaaattcat
    15061 agaagaagcc atcgtgacat caatcgtacc tgatcctaaa aacccgatgt accgtgtacg
    15121 aaacggtgaa gttggtttag ttgaaggttt ccgcatggga caaattttgg atcacgttta
    15181 cgaagaagat aaagacaaaa aagtgaaacg gccaatcatc gttgtgatcg atgtaccaag
    15241 ccaagcatac ggctataacg aagaattgat cggtatccat gtggctttgg ctaatagtgc
    15301 tgctgcttat gcaaaactcc gtcaagctgg acatccagtt attggattga ttgcaggaaa
    15361 tgctatttca ggtgcatttt tagcacatgg attacaatca agccgcttga ttgctttaaa
    15421 caataaagaa attaccgtcc aagcgatgtc taaagaaagt gctgcacgtg tgacaaaacg
    15481 ttcggttgct gaaatcgaag cagctgctga aaaagttcca gctatcgctt acgatatcaa
    15541 taattataca aaactaggag cgatctatca tttcctagaa gatatcaccg accaagctgc
    15601 ttcagaacaa aatgtcagca aagtcatcga agcaatcaat gaagccattc aagatgtccg
    15661 caatacaaat gacacgatgc tgacaaatcg atacacaaac gaaacagcca aaacattcgg
    15721 acgtgtcgaa acaaataaag tccgtgccaa aatggacgaa gaatgggatg cataaaaaat
    15781 gattcaagca catgatattg tcctttttga taaacatgaa atagaagggt tcaccttgcc
    15841 tgaatgggtc gttctaactg aaaagatgtt cggaacagtt cgtcgtgcgt cgacggatca
    15901 cgcagaaata ctaccgattg gtttacgtgg acctgcccgc aatcagagat ggtcaacaga
    15961 aatctcaaaa catgccgtca aacaagtcat tcatccgtgg gacatcatcg aacaagaatc
    16021 gtatagacaa gagaaaatca tggattatcc tgtttatcag caatttcatg ctgctagaaa
    16081 catattatca ggatgtaaat ggggaatcgg cggcagctta ggatttgaat tatcgactgg
    16141 gattccggca gtaaaagaaa ccagtgattt tgatttgctg ctgtacgcaa attcaccgat
    16201 tgaattgcca attcaggtaa ttcaatcgca tcctgctttt tttgagcaat tcgataccca
    16261 agtagtgact cggcaaggcg gtttttcact aaaagagtat ttgagagagc cagagaaaaa
    16321 aattctattg aaaacagtcg aaggacctaa attaaccaaa gaactttggt aataaagaaa
    16381 aagagagaga aagagatgtt tgaaaacaaa aaaatcaaaa tcaacgtaag tgacttccag
    16441 aaagtatcag ctgtaacggc tgttatgatg caaacgatat tgagctttgc tttggcaaac
    16501 agccacagcg caacaaatac agcttttctt ggtacctttt acgtcatcgt taaatacaca
    16561 gcaccaatgt ttatttttgc aattgtttat aatatggtaa aaacaagtca gcatttgtct
    16621 tattgggaat ttttgaaaga aaagtttttt gaactagtcg ttccgtatct tctatggacg
    16681 acggcttatc tttggctatt tccagcagtc caacaacaaa ctccgtatac ggatactgca
    16741 agctttttac tgaaatatgt cacaggtgat ggagcgcctc atttatggta taccgttatg
    16801 atgctgcaga tccaattgtt catgccgttt tttgtttggc tcggttacaa agtatttgct
    16861 aataaaaaat atgtatggcc agtattgatt ggttcaacga ttttatatgt cgcatggtat
    16921 ctgttctatc aaacacaagt attgactggg ccttatcatg acagctggta cttattagat
    16981 cggtttgttg ctagtttcat gatttatggg gtagccgcat ttgtttatca cgaaaaagtc
    17041 tatcaatatt tggacagagt acgttatctt ttcttacctg ttgccttagt tatcgcgttc
    17101 ttttctgtcc gttcattgct cgcacatcca ggagacttga gctttgcgaa tgcaccttac
    17161 ttgaatacga tccaaagttt atacagttta gtcatcatct ttgctgtctt cataggcgct
    17221 tccaaaatga ttgtaaacga ttcgccaaaa ttgccattgt tcaaatggtt gtctgtttat
    17281 gcttatcgta cgtatttagc caatgtattt gttttccaag tactgttatt attgtttaaa
    17341 gatagttggc tgcagttacc ttcaggagtc atgattcttg tagcttatct aatgacggca
    17401 agttgtgcat ttgctttaag ctggttactt catatcattt gggtagctat caaaaaaggt
    17461 ttcagcaagt aatagtagga agaaggagtg agtgtcatga taaatgacga acgaaaaaaa
    17521 gcagtgactc agcaactcgc tgcgttggta gaggaagcat tgatcgcaga agtaacatta
    17581 agtccaaaac ctggattagt ggatgcactg gatgcgggtg cacattccga tatggactat
    17641 gctttatttc ttaagtctgc taagacgcta actccttttt ttgaagaaat ggctcaaata
    17701 gcatggcatc atgctattga tcaggagtta agagaaagaa ttgctgagat tgggcgaaaa
    17761 gcggaaaagg caatgctgat tgctacaaat ggcatcaata cccataaagg agcgatttgg
    17821 gcaatggggc tattgatcag tgtcattgca caaaaaatca gtatggaaca gcctttttct
    17881 ttatcgaaaa tacttgatga tgtcagcaag cttgctgctt ttcctgatac aaaatatcgt
    17941 cataaaaaaa ccactcatgg tcatagggtg aagcaaaaat atggcgtaaa tggtgcatat
    18001 gaagaagcga tattagggta tccgcatatc aggcttgcaa ttcaagcagc taaggagcta
    18061 gataatgatt catatgtaca gaaacaaatg catatgttgt tagttttgat gagttcgcta
    18121 gatgacacat gcgtattgca tcgcagtgat cagaaaacgt tagtggaaat gcaaaaactt
    18181 gctcatgctg ctagtcaaag tgctttacca aatcgtccat ttacagcact gttgcacttt
    18241 tgtcaggaaa accaaatctc tcctggagga agcgcagatc tcttgtctgc aagcttgttc
    18301 atgctgaaga tagaggaatt atggactgcc gacacataca tttgtccgat gttactcaat
    18361 gactaaataa gacaaaattg ctaaaaaaac agtttatgca tctggttatt gactcttcct
    18421 tttagcaagg ctatcataaa aatagttttt tgtaataaaa gataacgagg aagacaatga
    18481 aaaaaatcaa ttatttagca atcattttgt tagtgggcct atgtttgttt gctctgccga
    18541 cccaaggatt cgctgtcgcg ggtggtcatg gtggaggtac atctagcggt cgaagttcgg
    18601 gcagaggttc atttggtggt cgttcatatg ggggcagtta ttttggcagt cgttcttacg
    18661 gcagagattc ttatgggtat tatggtccag gtacaggtcc ttctagttat gagcaaacgg
    18721 gatttcttgc attagctgtt ttgtcagtag gaggggtttc tgctttttct atcgtcaaga
    18781 ataaaagaca aaagaaaagg ctgaaagcgg agatattgtc ccgcatgtca ggaacggcta
    18841 aagaaaagaa agcacagttt ctggaaatcc aaaagatatt catgaagatc caatccgctt
    18901 gggaagaaga aactcctgaa aaagccagaa gctgttatac agacaagctg tttgccgaac
    18961 atcagaaagt tctgcaaaaa aacaaagcag acggtgtaag aaatcatact aaaaaaataa
    19021 ctattcagga agtaggaaat tatcgacaga tccacgaaaa tagttttgcc atccgaattg
    19081 atttcagatg ctgtgattat tcagtcgatc gaaaagatgg gcgattgatc tcaggaagta
    19141 agacacaacg acagtatttt tctcagatat ggtattttga tttttctgag aaagaaaaaa
    19201 gatggcaagc cgattttatt cagccgatta tgctggattg acaggaaata tttatgaacg
    19261 gagttgtgac aaaagccttg tcgcagctcc tttttctgaa taaacggtgt gccagagata
    19321 gcctatcggc aataaggcac gattttgtaa aatatgggaa gcgatttttc aaaatcgctt
    19381 cttatcgctc aaggctgaac atctctgtca caacctctcc actaaatggt gtttaaaagc
    19441 ttgcatctgc gataataaga acaaccaaac gaaaaatagg aagcactatt ttagtttagt
    19501 tgttcttatt acttgatgca ggacagcttt ttcacaacct cttttttgta tagatgggca
    19561 aaatttttgt aataataggc gtatgtcttt ttcgttgagg agatgaaaaa gcatatggct
    19621 tattttttgt ttgctttgct tactttcttt ccacttcaag tggcagaaat atctactttt
    19681 tattatgtaa gcggaaccat atacttgaaa tcagaaggag atcatttcta tgaaaacaag
    19741 aacaattgaa atacttcaca gaatcatgac agcccaatat ccagtaaaag caaaacatct
    19801 agcaagtgag ttcaatgtca gtcagcggac gatccgtcag gaagttcttg aagcgaatat
    19861 ctggttgagc agtaaaaagc ttccggagat ccgtacaatt cgcaacaaag gttttttgtt
    19921 gaagctggaa aaggaaaagc aagctcgatt agaaactgaa ataaaagatg tgaaagacgg
    19981 ctttttgaat cggcgcgaac gtatttttga tctagtttta gccgttgctt acagccgaat
    20041 cccgatccat ctaaacaaaa aagaagaaga atttcaaatc tctaaaagta cattagatga
    20101 agatatgaga cggttacgag caacactggt cagttatggg atagagatcg tcagttatgg
    20161 aaagcaagga ctggtttata aaggttcaga acgatctatc cgtacgatga tctatgattt
    20221 tatcaatcag aatctgggaa tgaccgactt ctttatgaat caagatgcac aattaacacc
    20281 ggctcaaaaa atctttctcc attattttcc tttggtggaa atcaaaaaaa tacaggagat
    20341 ctattccaat aagttgttga aacaagaaga tgatatttat aaaaaacaaa tcctgctttt
    20401 tacattgatc tggatccagc gaatcaggaa acatgaattt atctctgcca ttaattggaa
    20461 aaatacagaa ataaaagaca gtagcttttc tgcatttatt gaccacatga tcgaggaatt
    20521 tcaattggac aatgtcccgc aagtagaaag aaattatctt cgtttcacta ttgagacgtt
    20581 caatgctaga gatatctcca attcaatcga gtgggtacaa gctcaattac taacgatcca
    20641 attgatccaa tttgtagaga acgagacaca cgtacctttc catctaaagg aagaagcttt
    20701 attcgaaaat ctctataagc acatggctgc actgattgta agaatcaaga atcatatcca
    20761 agtcatgaat ccattgaaag aaaacatccg aacaaattat ttcccaatct accgcgcagt
    20821 cactcatttt gttcctacga tcgaagaagt aattggtggc aagatactgg aggacgagat
    20881 agcttttctt gtcatccact tttcgacgat cgccagtgta atcaagcgag acttgaatta
    20941 tgtttataaa tcagtcgttg tctgtaacca tgggatggct actggaaatc tgttagcaga
    21001 gaatctgaaa gaaaagtttc ctcagatcga gattactgca gttttaagtt caaaagaaat
    21061 cgaattagta gataaattgg atgtcaatct ggttttcagc acctttcaat tgaattatcg
    21121 aaataagccg cttttagttg tcgatccgat tttaactgag acgaatatct tggttataga
    21181 agactttttg aaaagaaatg aagaactaca gcggttagag cctaacagtc atgaatcgac
    21241 ggagttattc actcaaataa tagatgtcat gaaagaaagt ggtggccgag tagatcgaat
    21301 catctatggc aagttagaaa aattattcga aacaaacaat ttagaaatca acaaaaggga
    21361 gatccagcct atgttaaaag atattttgac ggacagcaat atcatgatca aagaaaaagc
    21421 cactacttgg gaggaatcga ttgaactagc tgctagacca ttggttaaag aaaacattgt
    21481 cgaagagcgc tatgtcgaag cgatgattcg tgcagtgaat gattacggac cgtatatcgt
    21541 gattggcaaa cacatggcac tagcccatgc ccgaccagaa gatggggtca ataaattagg
    21601 agtcagcgta gctacgattg agcaaccaat cgatttcggt aatcctgaaa tggatccagt
    21661 aaagattatt ttttgtttgg cagcagtaga ctcctactcg catctgaaca tcatgaaaga
    21721 actaattgaa ttgatcaaca acgaagagaa gttggatcga ttgattgaat gcacaaatat
    21781 cgaagatttc aaacaactgc ttttttcagt agttgagaaa taataaatga tacgggggag
    21841 aacaaagatg aacaaattga acattttatt cgtatgcggt gcaggtttag gaagtagttt
    21901 tgcagcacag atgtctgctg aggatgtttt gaacaaatta ggagtagaag ccaaactgga
    21961 ccattgtgat atttcttccg cagtttccat gaaaccagat gtgatcatca cagcagaaaa
    22021 ttttcgttcg cagttcgaaa agttcgcagt tgatcctaaa acggcgatga tctatttgaa
    22081 aaatattgtt tcaaaaaatg aaattgaaga aaaaatcacc ccagttctgc aagataaggg
    22141 agttatctaa atacaaaaag aaaagagggt aaaaa
//
LOCUS       DAZAOD010000043        21600 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000043 DAZAOD010000000
VERSION     DAZAOD010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.044"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(317..1813)
                     /gene="lysS"
                     /locus_tag="ACHDPO_001593"
     CDS             complement(317..1813)
                     /gene="lysS"
                     /locus_tag="ACHDPO_001593"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFN3369214.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1924..2928)
                     /gene="dusB"
                     /locus_tag="ACHDPO_001594"
     CDS             complement(1924..2928)
                     /gene="dusB"
                     /locus_tag="ACHDPO_001594"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFN3369215.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2929..3816)
                     /gene="hslO"
                     /locus_tag="ACHDPO_001595"
     CDS             complement(2929..3816)
                     /gene="hslO"
                     /locus_tag="ACHDPO_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFN3369216.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4033..6144)
                     /gene="ftsH"
                     /locus_tag="ACHDPO_001596"
     CDS             complement(4033..6144)
                     /gene="ftsH"
                     /locus_tag="ACHDPO_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFN3369217.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6234..6779)
                     /gene="hpt"
                     /locus_tag="ACHDPO_001597"
     CDS             complement(6234..6779)
                     /gene="hpt"
                     /locus_tag="ACHDPO_001597"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFN3369218.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6779..8224)
                     /gene="tilS"
                     /locus_tag="ACHDPO_001598"
     CDS             complement(6779..8224)
                     /gene="tilS"
                     /locus_tag="ACHDPO_001598"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFN3369219.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8344..8814)
                     /locus_tag="ACHDPO_001599"
     CDS             complement(8344..8814)
                     /locus_tag="ACHDPO_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFN3369220.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8860..9285)
                     /locus_tag="ACHDPO_001600"
     CDS             complement(8860..9285)
                     /locus_tag="ACHDPO_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFN3369221.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9352..9621)
                     /locus_tag="ACHDPO_001601"
     CDS             complement(9352..9621)
                     /locus_tag="ACHDPO_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFN3369222.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9632..11227)
                     /locus_tag="ACHDPO_001602"
     CDS             complement(9632..11227)
                     /locus_tag="ACHDPO_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFN3369223.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11242..14763)
                     /gene="mfd"
                     /locus_tag="ACHDPO_001603"
     CDS             complement(11242..14763)
                     /gene="mfd"
                     /locus_tag="ACHDPO_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFN3369224.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14780..15340)
                     /gene="pth"
                     /locus_tag="ACHDPO_001604"
     CDS             complement(14780..15340)
                     /gene="pth"
                     /locus_tag="ACHDPO_001604"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFN3369225.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15693..16667
                     /locus_tag="ACHDPO_001605"
     CDS             15693..16667
                     /locus_tag="ACHDPO_001605"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFN3369226.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16837..18237
                     /locus_tag="ACHDPO_001606"
     CDS             16837..18237
                     /locus_tag="ACHDPO_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFN3369227.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18315..19037)
                     /locus_tag="ACHDPO_001607"
     CDS             complement(18315..19037)
                     /locus_tag="ACHDPO_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3369228.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19116..19622)
                     /locus_tag="ACHDPO_001608"
     CDS             complement(19116..19622)
                     /locus_tag="ACHDPO_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFN3369229.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19745..21544
                     /locus_tag="ACHDPO_001609"
     CDS             19745..21544
                     /locus_tag="ACHDPO_001609"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFN3369230.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         6003 a         4717 c         3877 g         7003 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataacttttt tgttatgttt
       61 ttgaataaat attttcttct gtcttttgga caagtaataa tataccaact aaatttagct
      121 tggtcaacga attttttgta ttttttcaag tttttttcaa taaacgatta ttcataactt
      181 ttctttcttt atcgttcgtt ttcgtcttct ttaatgtcta gaatagtcgg cattagcttt
      241 tgaactttcg ttattattta ttcctttcta cacagcaaaa gctgcctaag gaattcctta
      301 gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga attgattgtg
      361 catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca gttggcggca
      421 taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg tcatttccta
      481 gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga tcgttcagtt
      541 ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga tctgtgaatc
      601 gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt ccgtatacaa
      661 acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg ataacatgtc
      721 cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct aatgcttctt
      781 ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca tctaccatat
      841 ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg atttttgctg
      901 ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc attacatcat
      961 tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta tgtgtagtat
     1021 caattccttc attacggaaa acgcggccga tttcataaac tttttccatt ccgccaacaa
     1081 ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg tccagtgcat
     1141 tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc aatactggtg
     1201 tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg ataatttggc
     1261 ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag tagcgttgtc
     1321 tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga cgaagtgctt
     1381 ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct gttttcatga
     1441 tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact tcataggcct
     1501 catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga tcttgtagat
     1561 gcgcaaatcc agctttccct tttcctcggc gagtcatcat acgaccagct acactagcgg
     1621 tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca tgcaattctt
     1681 ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct tcacgcaatt
     1741 gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact tgatgttgtt
     1801 gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat aatgccaatg
     1861 aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg aaaaacttag
     1921 aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt gatccagcag
     1981 gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt tcgctgctcg
     2041 aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaag ctactttttc
     2101 tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt tttcggctgg
     2161 tgttggttca ggaatcagtt cccctgtttc gagataatgc tgtgtgcggt gaatcatcca
     2221 tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat agtcaagcat
     2281 ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggaa tcgtcaaatg
     2341 ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct gaacccgtgt
     2401 acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg cattttctac
     2461 agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg ggatatttac
     2521 tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa gccattttgc
     2581 tcctgcttct gctttgatta ctttatttac tggacagccc atattgatat ctattatatc
     2641 ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt tatttccgcc
     2701 aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct ctaaagtttt
     2761 tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta agcccgcacc
     2821 aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg gtgcaacaac
     2881 gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt aaatccctcc
     2941 taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt tgttattaca
     3001 gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga tttcttctgc
     3061 acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt tgaattgaac
     3121 aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca atatttcttc
     3181 tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta attgttcttc
     3241 gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga atcctcccgc
     3301 cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg aagggatttg
     3361 ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa caatcggcgt
     3421 ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca ttccttgtgt
     3481 tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac tgagatgcgg
     3541 atttttgatg taacctttca catctccctt tccatttgca tctactacaa ttcctgttgc
     3601 tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg tcgcaccaag
     3661 tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc aagtatcatg
     3721 acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc ggacgaatcc
     3781 gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc tttttccgtt
     3841 tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg gaatgcttct
     3901 tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac aacttaaata
     3961 aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc agatcaattg
     4021 acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt gttgagaatc
     4081 tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt caaaatcacg
     4141 tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg cttcttcaaa
     4201 agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag gcatcacacc
     4261 gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca aaagtttttc
     4321 agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt tatcatgagc
     4381 ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt ccgagtaagc
     4441 ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat attgaacagg
     4501 acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag ctgtcgcttg
     4561 ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt cagctgtacg
     4621 tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca agaactgatc
     4681 ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga tcgttacttt
     4741 gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag cttcgtgata
     4801 agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg gacctgcaat
     4861 cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat ttcttctagc
     4921 agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa aacctggtgt
     4981 ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc gtgcatggac
     5041 tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct ggcggtcaaa
     5101 acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg cagcaatgac
     5161 gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt tcaatgtttg
     5221 ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta ccgcatcaat
     5281 ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca aatcacgaac
     5341 acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga tcgagtaaaa
     5401 cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg ttcctggagg
     5461 tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc ggcgaggatc
     5521 tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac ccgctacatc
     5581 agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt taccaaagtt
     5641 catgacacgg ccgccaccgc caccgccgcc gccttgttgt cccatcatca tgtaaaagaa
     5701 aaagatgatg attacgattg gcaagaagct aagcaatagg gaaacccata taccgctgct
     5761 tgattcttct tttactgttg tagcaacttt gttttctttt gccagttctg ttacttggct
     5821 caatgttgta tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg tatctgttga
     5881 acctaagata gctaacccac cgctgttagc gacggtctgc tgttctttgt attcaccagt
     5941 gatcttatat acaccatttg caggctgcac ttcaaattct ttgatcttgc ctgcttgtag
     6001 ttgttctgtg aattttgagt actcgatatc tgacgatcgc tggccgttat taccaaaaat
     6061 gaaataaacg accattacca tcgctaagat tacgaggaca taatacaagg catttttcat
     6121 catgccgttg ttctttttgt tcatagttgc cctccctaag cgtcaattta atttaacagt
     6181 tttttatcaa tcctgaccat tctattgtac cataatttaa ttgagataca gcattaattt
     6241 gattgataaa cactaggttt caatacaccg atgtacggaa ggttacgata tgcttctgca
     6301 taatccaagc cataaccgac cacaaattca tttggtacgt tgaagccaac ataatctgct
     6361 tcgatattta ctactcttcc ttcaggtttg tcaagtagtg taacaatttt gactgatttt
     6421 gctttgcggt atttgaaaag atccactaaa taagcaagtg ttcttccgct gtcaatgata
     6481 tcttcaacga tcaacagatc gcgaccttct acattcgtat ctaagtcttt gacgattttt
     6541 acttcccctg acgagactgt tgcattcccg tagcttgaaa catccatgaa atccaattcc
     6601 aaatacgtat cgatagaacg aacgatatct gccatgaatg gtaccgctcc ttttaagaca
     6661 cctactacta ggggattggt gttttggtaa atttctgtta actctttgcc tagttctttg
     6721 caacgaactt gtatctcttc ttgtgagatc aaaattctct caatatcctt ttccaacatc
     6781 aggttctcct tccaattgct tctttttgat atttgtaaag aagtatgtag tgtattttat
     6841 cagtttcttc acgaatactc aaatatgaaa aggcaaaagg tatcaagcta tatatatttc
     6901 ttttggcatc tgtaatgatc caagcatgct gcctttgtga attaggtact ttctgatcga
     6961 taaaatatct agatactttt tttgtgagat tctctgttaa tttaatgcgg tctcctgctt
     7021 ttcttttttc gacatacagt tgcacatcag caggaatcca aatgtcatga gaaaatagag
     7081 accatgaatc tgttgctttg atgtcccctg cattttcagg tttgaccaga ccaatccatt
     7141 ctgtttcatt caaatatatt ccttgttctg gaatcagcaa caagcgctgg tcttctgtct
     7201 ggctagttgc ttgtttttct tttttagaga gtacaacaaa atgatactct cttttcagta
     7261 tccaattatt gccaatactg agttgccatt ggcttttttt ctgttgccac tggtctaaaa
     7321 tcgactccat ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct ttgtcgaaaa
     7381 aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt tctgcagaaa
     7441 atcgaaattg ttcctcccac tgttcgactt ccttttcgat caactgtccc atatattttt
     7501 gaatgacttg gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt ctcaacgcct
     7561 gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg aagccgattt ctctggatat
     7621 ctaacaattg gtttgtctga tcctcaaagt aaacaagctg cgattccgct gcataagtat
     7681 ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta gcaaatggtt
     7741 gtacttcttt gattccagaa aaagtattta actgtccccc acgaacgatt ttcattaaca
     7801 ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat tgtccttctt
     7861 ccatcacgcg agtgaattct tgataacgaa agttacgagc ttctgtttct atggcggatt
     7921 tggctggatc ttcccaaata cttacatata aagggagatt cttctcttca caatatgagc
     7981 gaagataggc agcttcttct gctgattctt ctcttaattg gtgattgatg tggacgatac
     8041 ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa atggagcaaa accatcgaat
     8101 caacaccacc tgataccgct gctaaaattc tcgatccttg ttgccagaat ccttgttcat
     8161 tcccgtgccg aataaatgac tgctgtaata gcggtgcttt tttcccgcct ttttcaacgt
     8221 tcatcctttc cacacccttt cttcctaaaa aaaagagagc gggaaaacgt ctaaaacgac
     8281 aattaacctg ccctctgttg atactatgac ccaaatagtc gcactatcat tatttgcggc
     8341 tttttagctg cgacgtccgc cacggccacc gcgctttcct tctgtgtttc gcttcaatga
     8401 agataagcgg tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga agtcttcttt
     8461 ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt gctggacgat ttcggttgtc
     8521 acggggatct ttttgttgat attttttagg acggctttct tctccagatt cagcaggttg
     8581 ttcctgcgct ttccggatag atagtccgat ttttccatca tcatttactg aaataacttt
     8641 aactgttact tcatctccta cacttaaaac atcatggatg tcttttacat agccatttga
     8701 cacttcgcta atatgaacta gacccgtttt tccagcacct agatcaataa acgcaccaaa
     8761 atttgtgatt cctgatactt ttccttgcag ttttgctcct acctcgattg acataaaaaa
     8821 aatgttcctc ctaattattt ccctttttta tattcctgct tattttgcag ttgtagaact
     8881 agttgattga tctgtttcat ttgtcgagct gtctgtattt gattctaata taggataaac
     8941 tttttcaccg tcttttgagt aaaagaattt gcttctggca agtttagcta catactcatc
     9001 atctttcagc aatgaaacat cttggtgcag ctgatcaacg tctgcgttga cttctttcat
     9061 ttcagtattt gcttcgactc tcaattcgtt caattgatgc atcctttgca tgtcatggaa
     9121 aatctgcaca cctattatcg cgaaaatgac caaagcacca acaaaaattg cagccagtct
     9181 gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat tcagcatact ttttctttgc
     9241 atattccgta tctagcgcag cgattttatt gctttttttc gtcacttgga ttcgctccaa
     9301 tctttttgat tgtctttttc attataccaa tatcgtgaaa gcttgtctaa tctatttctc
     9361 tagtgtttct gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat cttctttttt
     9421 ggttgattca tgtaattccg taattttcac ttccaacgtt ttgttgccaa actggacttt
     9481 caaaatatcg cctactttga catcactgga agatttcgcc aatttaccgt tgatttgaat
     9541 tcttccttta tcagctactt cttttgctac tgatcgtctt ttgatgattc gggaaatttt
     9601 taaaaattta tctaatcgca tatcttattc ctcacttttt aattttttta tttaatcgca
     9661 ggattttctt accaaaaggc aacattagcc attctcgtac tgtaaacaga cgaagacgaa
     9721 tcactgcata aatgaacaca gaagccccga tcccaactcc tatcacgctg acaaaaaaag
     9781 cagtggaacg atgagttaca ggaccaaata ctatattcaa tacaccataa tacagcagca
     9841 gtactactgt catacaaaga aggctgaaca tcaacttccg tccaaaatgc cgttctttcc
     9901 aaaaagcatt tagctctttt gtttcaattc gaacaaaata ccaaagcgtc acacctaatc
     9961 ctaaaagggt agacaggctt gcacctgctg ttcctaataa accggtcaga aaagaagtag
    10021 tcaatccttt taccaatagt ccccatcctg cgccttttaa agaagggcga aacgagttct
    10081 tgctttgagc aatactttga taagcttgga tgactgcagt gaaagcaatg gaaaaaacaa
    10141 ataatacaag cgctgcattt cccgcataat ctttaaacaa cgcataattg atataaggga
    10201 gcagcaaggc taatcccaaa gacgcagcta atgctaaagc ggtcgtcaat ctaagataga
    10261 ttttggctgt ctgtaaaaac tgacgataga tccggttggt caaatgacga gtcaacgcag
    10321 gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc taattgtact aaaggctgac
    10381 ctcgatcata gacccctttt gctatcttcg caccgtattc tgacagtccg taaacttcca
    10441 aagcattttt tacaaagaaa gagtcgatca gctggaaaaa gataagcaat ccactataaa
    10501 tcgaaaccag tccgccttct accagaaaac gccggatcaa gggctttgac ggctgtttga
    10561 acaatggaaa ccgtcggaag cttaacgctc ctccatgaat cttttgttca tagtagtgaa
    10621 ggatcccata tgcgcataaa ccgccaaaaa cagctccact cattgctgcc gtccctgttt
    10681 ggtacaccgt ccatccaagc tttctaaaag caaacgcact acagacaatc acaaaaacac
    10741 gaacgaactg ctcaactact tgagaaacag cagttggttc catcaagaat cttccttgga
    10801 aattccctcg ataaaaagat agaccaggca tcagcaaaaa ggtaaaggaa actacttgga
    10861 tcagcggttt caattgtatg tctcccatca tccaagcaat ccagctgcta aatgcaaaga
    10921 caaacaacca caaaaagaca cctgtccaaa atactaaggg ataaagattt tgcaaagctt
    10981 gctttcgctc gaaaggattc tttctttctg caacgtactt tgatatgaac tgcggaagac
    11041 cggataaagc taaagtcatt gctatcccat aaattggata aacttgctga taaacataaa
    11101 aaccttcgtc gccgactaag ttttggaggg gaattcggta aagggcactt aatacttttg
    11161 ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat gacgcgccgc atttctttat
    11221 gatccaaatc attgctcctt cctacgctga cagatatttt tgctcacgca acgctttgac
    11281 aaacttttgg atttcctgaa gccatactgc ttcttccatt tggttgggga tcgtcaagcg
    11341 tatcaccatc tgttcttttt caacgcctag actggctttt agttttgtcg ctgtcagtgc
    11401 ttcgaataac tgttccacac tatagcgttt tgttccaact ttacttagag taaagactat
    11461 atgcgcctcc tgtttcctta tcgtttctag gagcgctcga tcgccatcca ttttgatctg
    11521 cccaattgtc aagagatgtg ctacttcttc tggatattct ccaaaacggt cgagcagatc
    11581 atcttctagt tcatctagca tttcttgcga atcaagttca cgaattcgtt tatagatctc
    11641 gattttctgc cgttgatctg ccacgtatgt ttcaggtaga tacgcatcga caccgaggtc
    11701 gatctcaaca gtggtcttct ccacttgact attctttcct tgtttacgag aaacagcttc
    11761 gcttagcatt tgagaataca tatcgaaacc gactgcatca ataaatccat gctgctgagc
    11821 acctaagaga ttacctgcac cgcgaatgga aagatcccgc atcgcaatct tgaatccaga
    11881 tcccagttct gtaaaatctt tgattgcctg aagacgtttt tcactgactt cgttaaggat
    11941 cttctgctgc tcatacataa agtaagcata tgcgacacgg ctgcttcttc ctacccgccc
    12001 tcgcaattgg tataacgtgg ataatcccat ataatcagcg ttctcaacga acaacgtatt
    12061 tgcgttcggg atatctactc ctgtttcaat gatggttgta gtgacaagaa catcatattg
    12121 accttcaata aattcaaaaa gcgtattttc taattgcgcc tctgtcattt gcccatgagc
    12181 ataaccgatc cgtgcttccg gaacgagttc ttggatttct tctacttttt gttcgatcgt
    12241 ttctacccga ttatataaat agaatacttg tccacctcgt cccatttctc gatggattgc
    12301 ttcgcgaata gccccaggat ttttttccat aacatacgtt tggatcggat aacgattcgc
    12361 aggcggtgtt tcgattactg aaagatcccg cacgcctaac atcgacatat gcaaagttct
    12421 cggaatcggt gttgcagtca gagtcaaaac atccacttgt gcacgtaact gtttcaatcg
    12481 ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg atcagtagac ccaaatcgct
    12541 aaattcaata tcttttgaca aaattcggtg ggttcctaca acaatatcaa cttgacctgt
    12601 acgcagttgt tcgatggttt ctttttgttg ctttcttgtt ctgaaacgac ttaatagccc
    12661 gatatttacg gggaaacctt caaatctttc cagcatcgtt tcatagtgct gctgtgccaa
    12721 gatcgttgtt ggaactaaaa aggctacttg tttgctttcc tttatcgctt taaaggccgc
    12781 tcgaagcgct acttctgttt tcccataacc aacatcacct acgagtagtc gatccattgg
    12841 tttttctttt tccatatccc gtttgatctc cgctgcactt ctcaactggt catcagtttc
    12901 agagtagggg aaggcatttt cgaattcttt ttggtaggcg tcatcaggtc caaaagcata
    12961 tcctttttct gactctcttg cggcatataa tttgattaga tcgtcagcga tatcctcgat
    13021 ttttgaagag acttttcgct tggttttcgt ccattcactt ccgcctagct tattgatgcg
    13081 aggcgctttg gcttcagagg cgacatattt ttggatcaga ttcagttgag taacaggaat
    13141 aaacagtttg tcgtcgtttt gatacaaaat agtcatatag tcttggtgaa cgccatctac
    13201 ttctagcgtt tccatcccaa tgtatttccc gataccatga ttggcatgga caacgtaatc
    13261 tcctgctttt aactcattat agcttttcaa tcgctctgcg tttgttactg tttgacgtct
    13321 cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct gtgatagcta ctattttttc
    13381 ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact aattgtacct gtcctctgat
    13441 caatgcattt ttttctgttt ctactactaa tatgtcttca tctcgaagca tttgttctgc
    13501 tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca gtctgttttt gcttgcgcca
    13561 acggtccatt tctgttttca gcaatggcat ttgtccgaag aactgttgca tcgtccgata
    13621 ttgaaaatta tggattgctt ggaaacgaag atttcccatc cctttttgga agagtgagaa
    13681 aaaggttgtg gtgaactttt ccttctgcac gattttttgt atatctgctg aaaatgtctg
    13741 ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc cattctgccg cttccctttc
    13801 gatttcccga tttgtttcca tgattcgctg ataatcatca acgactagta aactatttga
    13861 agggaaataa tccaagatcg tcacagattc ttggtaaaga agatctgagt agaattttgc
    13921 ttcttctgtc gggacacctg cttgccagct tgaagtcagc tgaccgaagt aatcttgcaa
    13981 aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt ttttctagca ttttttgcat
    14041 ttgctctatt ccatgttcta gatcctctgg tccgtagact tgttcactcg ttggggaaac
    14101 ccagatttct tccgtttttt cgattgagcg ttgtgtttct gcttcaaaat accgcataga
    14161 atctatctct acatcaaata gttctacacg aacaggatag gttgtcgtta acgggtaaat
    14221 atcgataatg cttcctcgaa tactgaattc tcccggtttt gcgaccatct cttctcgtac
    14281 atagcccatc aaagtcaatt ggcgaggaag attttccacg tctatctcat caccaatatg
    14341 ccaattcaat tgcgcctgta gccaagtttt cttattcggc agtcgtttgt gcaaagatgc
    14401 gactggcaac aaatagatac ctgctttttt ttcttgaagt gcgttaagcg ttgcaactct
    14461 ctcgcctcgc gcttctggag aagaaaaggc catttcagca gaaagcactt catccactgg
    14521 aaataaatgg atctgatctt gcggaatcac atgttgcaga tcttctgcta actgattcgc
    14581 ataatacaaa tttggcatca gaataatcat gtttttattt gttttcttaa acgctcgagc
    14641 aaatagaagt gttttcgctg agcccgctaa tcctgtgatt agttgtctag gcattttttc
    14701 ttctaaattg ctgacccatt cttttacttg cggatctttt ccgactaatt gaataatatc
    14761 cattcctttt cctccttcct caattgaatc gattcatcgc atccacgaac gaatgccctt
    14821 ctatgagata ttcgactgct ttaacagatt gacacatgct ttcttctatc aaaggctgat
    14881 tttctttgct gaaaggacta agcacatgct ggactactgt ttttttccct tctggcctgc
    14941 cgattcccac cttgattcga tcaaagacat tcgtattcaa atgggaaata atacttttga
    15001 taccgttatg cccgccggca cttccctttt gacggagccg gatttttccc actgccagat
    15061 ccaaatcatc gtagattacg actaattcct ctggataaat cccaaaataa gtcattagtg
    15121 ggccgactgc acgaccagat tcattcatga atgtttgtgg tttgactaaa aggatctttt
    15181 ctccattatg aaaaaattcg gcaacttctg cttcgaacgg attttttttg aaagtagctt
    15241 gatgctcgcg tgcaatttta tccacgacca taaagccgat attgtgtttt gtatattggt
    15301 atttggtacc tgggtttcct aacccgacga tcattttcat ttttgttttc cacctaattc
    15361 taaaaagcag cacaaaaggc tggactgcta attagcggtc cagtccatcg agcttttttc
    15421 ttttttacac ttgtcaatgc atagtataac acaaaacaag gcgtttcggc taaaagagaa
    15481 tcgttaataa atgataaaga aattaaaaat ttcttcaaag tttaatgaaa taattgatat
    15541 ataaaaatag tgaaataacg cacatgtaag cttttacata taatacaacc ttgttatctg
    15601 ttatatttta tagccaaata gcgtgacatg gggcttgaga aatgttagca taagcatggg
    15661 aaaaaacaaa tcaatggaag gattgatact aaatgactgc agctgcagaa aaaaaagatc
    15721 atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc tagctatgcc tttgctctag
    15781 ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat caatactgct aaaactgaag
    15841 gagacgcaat tgacttgtct cacgctttgg catttacttc acctaaaaaa atctattctg
    15901 ctacttacgc agacgcacat gatgctgact tagttgttat tacagctggc gcaccacaaa
    15961 aaccaggtga aactcgttta gacttagtaa acaaaaacct aaaaatcaac cgcgatgttg
    16021 tcacacaaat cgttgaatca ggatttaacg gtatcttttt agttgccgct aacccagtag
    16081 atattttgac ttactcaact tggaaattct caggtttccc taaagaacgc gtaatcggtt
    16141 caggtacctc tcttgactca gctcgtttcc gtcaagcact tgcggaatta gttgacgttg
    16201 atgcacgtaa cgtccatgct tacatcttag gtgaacacgg agattcagaa ttcccagttt
    16261 ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg ggtaaaaaac aacccagaaa
    16321 tcgatgaaga agctatggtt aacctattct ttggcgtacg tgacgctgct tacacaatta
    16381 tcgagaaaaa aggcgctact ttctatggta tcgcagtagc attagcacgt atcactcgtg
    16441 ccatcttaga tgatgaaaat gctgttcttc ctttatcagt attcatgaat ggcgaatatg
    16501 gattgaacga catctacatt ggtgcacctg ctgttatcaa ccgtcaaggt atccaaaaag
    16561 taatcgaaat tcctttaagt gacagcgagc aagaccgtat ggctgcttct gctaagcaat
    16621 taaaagaaat tctagatgaa gcttttgcta aactagacgc tgaataatct ttgaacatga
    16681 cggaaaacat ctattcggtg ttttccgttt ttttatttta tcacccttat ggtttctaaa
    16741 ttttttcata aagtagagat aaccttcgtc ttttcctcta aattatgcta tcatgagacc
    16801 gttccaccct aaacttttac ttaaggagtt gtcgatatga caagatcttc gcatcgaaaa
    16861 aaatcgaaac atgttgcttt gctttcagtt cttggtgttc tcttagtgct gatcagcttt
    16921 tatacctatc gcagtacata ctacacaaag cattttttgc cgaatacaga aataaatgga
    16981 ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa aattaaaaga agcttattct
    17041 gataaaaaac tggctattaa agaagatgga aaagtctggc aggaagtacc aaaatccgag
    17101 ctcggctaca aagatgattt cacttcggag ctttctccga tcctaaatga acaaaacgga
    17161 tggacttggg gaatgactta tgtctcagcg gcagaaaaac aagaaataga tcctgtcagt
    17221 caaaaccacc aaaaactaga cactaccgtt cagacattga caactaagct gactgatttg
    17281 aacaaagacc ggacacctac tactgatgca acgatcgaaa aagcaggtga ctctttcgtt
    17341 atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg ctgcggtcaa acaattaaaa
    17401 agtgcggtaa actctggtaa agatacaatt gaattgactg aattcaaaga aaaaccaaaa
    17461 gtaacatctg aagacagctc actgaaagaa caactcgcat ccatgaatgc tatcgcaaat
    17521 gtaaaagcta cttacagtat aaacggtgag actttccaga tcccatcaag tgatattatg
    17581 agttggctga cctacaatga tggaaaagtc gatttagata cagaacaagt acgtcaatat
    17641 gtaacagatt taggcacaaa gtataacaca agtacgaatg acacaaaatt taaaagtaca
    17701 aaaagaggag aagttacggt cccagttggc acttacagtt ggacgatcca aacagacagt
    17761 gagacagaag cattgaaaaa agcgattctg gcaggccaag attttactcg ttcacccatt
    17821 gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag atacgtatat cgaagttgat
    17881 ctggagaacc agcatatgtg gtattacaaa gacggaaaag tggcccttga aacagatatc
    17941 gtttccggaa agccaactac acctacacct gctggagtct tctatgtttg gaataaagaa
    18001 gaagatgcaa ctttaaaagg aacaaatgac gatggaacac cttacgagag tccggtaaac
    18061 tactggatgc cgattgactg gacaggtgtt ggtatccacg attcagactg gcaacctgaa
    18121 tacggtggag acttatggaa aacccgcggt tcacacggct gcatcaacac cccaccaagt
    18181 gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc ctgtattggt cttctaacaa
    18241 aaataatata taaaaagaaa gcacccgtac gattggtaca ggtgctttct ttttattatc
    18301 taacaatgtg ctacttacat ttcagcagca gtaaagactt ctgaaacatc atcatcgtct
    18361 tctagcttat ctactagacg ttccaattgc tctttttgtt cctcatttaa atcaatcgtc
    18421 gtttgtggaa tcatcgtcaa ttctgcttgc gccaaagtga actctttttc caactcatct
    18481 cgtacagcag caaaatcttc tggtgcagta taaatctcga atacttcagg agaagtttgc
    18541 agatcttctg cccccgcctc taatacatcc tcaaacatcg tctcttcatc aacagtcaac
    18601 ccatcgcgtt caatagcgat atatcctttg cggtcaaaca agtaactgac tgaacccgtt
    18661 tctcccagtg atccaccgtt tcgagtaaaa gctactcgga catttgtcgc tgtccgatta
    18721 cggttatctg tcaatgcatg gactaagatt cctactccac ccggaccata tccttcatac
    18781 gtgatttcat cgtaattcgt ttcatctacg gcactcgtag cctttttaat cgcccgttcc
    18841 acattgtcgt taggcatatt tgcagctttt gctttgtcca caacaagccg caaagctgga
    18901 ttcatagatg gatcaggacc gcctgcttta gctgccatat aaatttcacg agaaagtttc
    18961 tgaaagactt tccctcgttt tgcatcttgg gcattttttc ttccttggat attatgccat
    19021 ttactatgtc ctgacatgat ttttcctccc ttgttctttt gagaatacac ttctattcta
    19081 gtactatttc acaaaaaaac aaagccacag ccaatctata aacgcttctt gaatgccgca
    19141 aaaagcacac ataatatcac agcagtcaga gcaccgatcg aatccaacat gacatcttgg
    19201 aacataggtg ttcgtccacc ggtcatcatc tgatggaatt cgtccaaacc tgcgtaccct
    19261 gttgctgaaa gccaagcaag gatcgctgtc agccaccaaa tttttagctt ggggaaaaca
    19321 cctaaaaaca agctgcctcc caaaataaaa taggtaccga aatgtgcgcc cttccttaaa
    19381 aagaactcta aaaatttggc gtagcccaga tggttgatac tcaccatact tccaccataa
    19441 ttaaaacgta tacccgctaa tgtgtcttta aatggctgat taggcagcca gctttctaat
    19501 cgcgaaactt gtgattgctg tccgtaagtt tgagaagaac tgtaaaataa gattataacg
    19561 actatcagtg cgattactaa ataaatattt ccgtttttca tttgtttttt tgaagaattc
    19621 ataagtcacc tctgtatttt atcttagact ttttttgaag aaacaacaat cattttcata
    19681 gagacttctt ccataaaaaa gtgctatact taattttgta ttacaatatg aagggagttt
    19741 tttcatgagt tattcattaa attggaatct agattctatt ttttccggag gcagtcattc
    19801 tgatgctttg aaccaacgga tgaagcaatt ggaagaccaa atgaacgagt attatcaccg
    19861 cgtaacaaaa tggtcaccta gttctgacaa tgcagagcag ttaaacgcta ttcttcaatt
    19921 gcaagaaacg attacgaatg gttttaccca atgcagcagc tatattactg cattgctttc
    19981 tgccaatgtc aatgattcag atgcaaaggt cttatcaggc aagctttacg caatgctgcc
    20041 tcgtctgcaa tcagccgaaa ctgtattgtc aaagaaattt gcagaaatat ctgacaatga
    20101 ttggaatcag atgctttctc aatcttcgtt tgaaacaatt gcttttcgtt taaacgagat
    20161 tcgtcgtgat ggctcacaat tattatcaga agctgaagaa aacattataa atacgctttc
    20221 tttagatggt ctaaatgctt ggagcagtca ttatgatacg attgtagcca gcatttcgat
    20281 tcccttcgaa caagatggac aagtagtcga attatctgct ggacaagcct tcaataagat
    20341 gatgggcgat ccagatccaa aagtcagaga aacacttttc gcagcatggg aagaagcctg
    20401 gaaagaaaag gcacccctct tcacggatac tttgaatcat ttagatggtt ttagactttc
    20461 tgactatgaa cttcatggtg tcacagattt tctacaaaaa ccattagagt acaatcggtt
    20521 gaagaaagaa acattgtctg tcatgtggga tacaatccag aaaaacaaac aaccccttgt
    20581 taattacttg actagaaaag ctaatctttt cggtaaagaa aaaatggaat ggcaagatca
    20641 agatgcacct attattttag gcgatttgaa agaaaaaacc tttagttttg acgaagcagc
    20701 agcatttatt atcgaaaact ttaacaaatt cagtccaaaa atggctaaat ttgcccaatc
    20761 tgcttttgaa aagagctgga tcgaagcaga agatcgtcct gggaaacgtc ctggtggtta
    20821 ttgtactgag ttaccagaaa caaaagaatc aaggatcttt atgacctaca gtaattctgt
    20881 taatgaggtt gcgacacttg ctcatgaact aggacatgct ttccatagca gcacgatgtg
    20941 ggatttacct tctttaaatc gcgaatatgc catgaatgtc gcagaaacag caagtacatt
    21001 cgcagaattg atcgtagccg atgctacatt aaaagtcgca aaaacaaaag aagaaaaaat
    21061 caatttgcta gatacaaaac tgcaaaatgc tttagctatg ttcatgaata tccattcccg
    21121 attcattttt gaaaatcgat tctatgaagc acggcaagaa ggattagtct cagaagataa
    21181 gatcacagag atgatggttg aggcgcaaaa agaaggctat caaggagctt tagctactta
    21241 ccatccatat ttctgggctg caaaattgca tttctttatt gatgacgtac cgttttataa
    21301 cttcccatac acatttggct acctctttag tttgggcatc tatgcttacg ccaaccaaaa
    21361 gggagcaaat tttgaagaag aatatatcca tttactacgc gatactgcct caatgacgac
    21421 ggaagatctt gcgaagaaac atttgaatgt cgatcttacc caaccagatt tttggcaagc
    21481 aggtatcgac atggtgactg aagatatcca aacgttcatg gaattgacag aagaatttat
    21541 ctgatttcta ttttatcaca ataaaaaaag agttagtcca gaatgggcta actctttttg
//
LOCUS       DAZAOD010000044        21577 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000044 DAZAOD010000000
VERSION     DAZAOD010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.045"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            87..1511
                     /locus_tag="ACHDPO_001610"
     CDS             87..1511
                     /locus_tag="ACHDPO_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFN3369231.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(1553..1810)
                     /locus_tag="ACHDPO_001611"
     CDS             complement(1553..1810)
                     /locus_tag="ACHDPO_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369232.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            1972..3081
                     /gene="pdhA"
                     /locus_tag="ACHDPO_001612"
     CDS             1972..3081
                     /gene="pdhA"
                     /locus_tag="ACHDPO_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFN3369233.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            3084..4061
                     /locus_tag="ACHDPO_001613"
     CDS             3084..4061
                     /locus_tag="ACHDPO_001613"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFN3369234.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            4086..5729
                     /locus_tag="ACHDPO_001614"
     CDS             4086..5729
                     /locus_tag="ACHDPO_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFN3369235.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            5737..7143
                     /gene="lpdA"
                     /locus_tag="ACHDPO_001615"
     CDS             5737..7143
                     /gene="lpdA"
                     /locus_tag="ACHDPO_001615"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFN3369236.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            7305..7580
                     /locus_tag="ACHDPO_001616"
     CDS             7305..7580
                     /locus_tag="ACHDPO_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFN3369237.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            7586..8353
                     /locus_tag="ACHDPO_001617"
     CDS             7586..8353
                     /locus_tag="ACHDPO_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFN3369238.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            8521..10350
                     /gene="typA"
                     /locus_tag="ACHDPO_001618"
     CDS             8521..10350
                     /gene="typA"
                     /locus_tag="ACHDPO_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFN3369239.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            10611..12383
                     /gene="recQ"
                     /locus_tag="ACHDPO_001619"
     CDS             10611..12383
                     /gene="recQ"
                     /locus_tag="ACHDPO_001619"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFN3369240.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            12497..12799
                     /locus_tag="ACHDPO_001620"
     CDS             12497..12799
                     /locus_tag="ACHDPO_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFN3369241.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            12802..13965
                     /locus_tag="ACHDPO_001621"
     CDS             12802..13965
                     /locus_tag="ACHDPO_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFN3369242.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            13991..17419
                     /locus_tag="ACHDPO_001622"
     CDS             13991..17419
                     /locus_tag="ACHDPO_001622"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFN3369243.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            17440..18564
                     /locus_tag="ACHDPO_001623"
     CDS             17440..18564
                     /locus_tag="ACHDPO_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFN3369244.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            18545..18991
                     /locus_tag="ACHDPO_001624"
     CDS             18545..18991
                     /locus_tag="ACHDPO_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFN3369245.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            18975..19313
                     /locus_tag="ACHDPO_001625"
     CDS             18975..19313
                     /locus_tag="ACHDPO_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFN3369246.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            19432..19992
                     /gene="rsmD"
                     /locus_tag="ACHDPO_001626"
     CDS             19432..19992
                     /gene="rsmD"
                     /locus_tag="ACHDPO_001626"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFN3369247.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            19989..20480
                     /gene="coaD"
                     /locus_tag="ACHDPO_001627"
     CDS             19989..20480
                     /gene="coaD"
                     /locus_tag="ACHDPO_001627"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFN3369248.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            20470..21513
                     /locus_tag="ACHDPO_001628"
     CDS             20470..21513
                     /locus_tag="ACHDPO_001628"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFN3369249.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
BASE COUNT         7318 a         3747 c         4739 g         5773 t
ORIGIN      
        1 cttatgtttt gcaaaaaaag tttttctttt ttctcgtaaa ttcggtaaaa tcaaaagaaa
       61 aaatagacaa tagaaaagag aagcttatgt gggaaaaagt agagaaaaaa caaggaccga
      121 tttatcgtca aattatggaa cagattatga gagaaatcga aaacggaagg atcaatcctg
      181 gaagtcaact tgaatcagaa cgaaaactag ggcaactttt tggtgtgaat cgttccaccg
      241 ttgtccatgc attggaagag cttagggagc ttggggtact aacgagcaaa cgtggcagcg
      301 gatggtttgt taatcagact gaatggggga aattcgctgt tccaagaatc gattggcggc
      361 aaatgatctc tcctcgttat gagcagacgg actggtatga gcaaaaaata agagaagcaa
      421 agcagatcca aaaaacatcg tttcttgatt tatacgctag cgagatgcca gatgagcttt
      481 tgccgaattt tgagtttcct tcttattctc ttgaagaaat cttagcggaa gaaaaagaaa
      541 tggatctttt aggctatact ccgttacgta acaaaatcaa acggtatttg gaaagtaaat
      601 ttgaattggc attttccccc aaccagcttc ttgtgactgg tggcggtcag caagcaatct
      661 ttttgatttt acaaacgatt ctttcagctg gagaggggat agctgtagag tcaccttctt
      721 ttttttaccg attacctctt ttcaaagctt caggaacgcg tttatttggg ataccgatgg
      781 atgaagaagg gatcgactta gaaaaactga aagaatcgat ccataaaaat aaattgaaag
      841 cagtgcttat caacccgaat tttcaaaacc ctacaggaaa agtgatgagt caaaaacgac
      901 gagaaaagct agtagaattg tgtcgacagt atcggcttcc aattattgaa gacgatgtat
      961 ttacggatct ttcatttcta aaccaagaag aagtccttcc tatacgaacg attgatccgg
     1021 ataatgtgtt atacgtcggt tcgttatcta gggttttagg aaaaacaacg aaaatcggtt
     1081 gggtgatagg acctgagact tttatctcgc aactagctca agcgcaagaa atgatggagt
     1141 tttcgatgaa tatccttaca caaatcacag tggctaatgt atttaatgaa gcaattgatt
     1201 tgaaaatgca agatgtaaga aaaaagttga aagaaaaaag ccgactgata agcgcttggg
     1261 gagattcaca atcgtttttc aagcttcatt caattttagg tggttactat gcctggatta
     1321 cttgggatgg gaaaaaacta gaccccgaac tagcagaaaa agtagtagat atgggtcttg
     1381 gaattgcacc aagtctactt tttgggcaag atataaatgg aatcagaatc aattacagta
     1441 ggctggatga aaaccaaata ccgttgtttt attcaaagat gaaaattcta gaaaagtggt
     1501 taacagaata atttcacaaa gtaaatagat taaagaatat aacagcttgg atttaaattt
     1561 caagctgttt cttttttttc ggaaaaagaa tacgatataa agaaactaag aaaaaaccat
     1621 tatttgtacg tccgttcacg atgtgtaaat aaaataaatg tttgcaacaa aactgtataa
     1681 caccaacgtt tttaaataga aacagatggt tgtaagtttg attagaaaat agaaaaaatg
     1741 cagatgaaat ataaaacgct ttccttattg tgattttatt cactaatgct gttaatatgc
     1801 ggattggcat aatttccttt catcgtgaaa atttgtgctt ttagcttgta tttctcataa
     1861 atccatgata atttattaat gaagacggtt aaatagtgat acagttttat tcactgtttc
     1921 aatcgcagaa tgaagagatt ttcttataga tgagagagga atgtgtgaca aatggcaaac
     1981 aaaaaagcac cgatcgactt ccaagcactg ctagatgaag tcaatgcaga tttcccagta
     2041 tatcaagcac ttgatcaaga tggaaacgta gttaacaaag atttagtacc tgatttatcc
     2101 gatgatgaac tcgttgaatt aatgactcat atggtatggt ctcgtgtatt agaccaacgt
     2161 tcaacagcgc tgaaccgcca aggacgccta ggcttttttg caccaactgc tggacaagag
     2221 gcaagtcagc tggctagtgc ttacgcattt gataaagaag atgttcttct tccaggttat
     2281 cgggatgtac ctcaactagt aaaacatggt ttacctttat ctcaagcttt tttatggtct
     2341 cgaggacatg ctgcaggtaa ttcttatccg gaagaattga aagctctacc accacaaatt
     2401 atcatcggtg cacaatatgt acaagcagcc ggtgttgcat taggtttgaa gaaacgaaac
     2461 aagaaaaatg tcgtcttcac ttatactggt gatggcggtt catcacaagg tgatttttac
     2521 gaagcaatca atttcgctgg cgcttaccat gcaaatgccg tattttatat ccaaaacaac
     2581 gggtatgcga tctctacacc tcgtgaaaaa caaactgcag caaaaacact tgcacaaaaa
     2641 gctgtcgcag ctgggattcc tggtattcaa gtcgatggaa tggatccgct tgcagtatat
     2701 actgtatcta aaatggcacg ggaatgggcg atcagtggaa atggaccagt cctaatcgaa
     2761 acactgactt atcgttatgg accacataca ctatctggtg acgatccaac ccgctaccgt
     2821 acaaaagaca cagatgacga ttggcagaaa aaagatccat tgatccgctt ccgtaaatat
     2881 ttgacggaaa aaggactttg gtctgaagaa aaagaagaac aagtcatcga agcaactaaa
     2941 gaagaaatca aagcagctat tgctgaagcc gacaaagtac caaaacaaaa ggtttcagat
     3001 ttcttgaaaa acatgttcga agtatctcca caatcaatca aagaacaaat tgcaatttat
     3061 gaagcgaagg agtcgaaata atcatggcac aaaaaacaat gatccaagca atcacagatg
     3121 ccttagcact tgaactagaa aatgacgaga atgtcgttgt ttttggtgaa gatgttggga
     3181 aaaacggagg agttttccgg gcaactgaag gattgcagga aaagttcgga gaagaccgag
     3241 tattcgatac tcctttagct gaatctggaa tcgcaggatt gagtttcggt cttgcgttag
     3301 aaggatttcg tccagttcct gaaatccaat tctttggttt tattttcgaa gcaatggacg
     3361 aagtagtagc tcaaatggct cgtacaagat atcgaatgag cggcactaga aatctaccca
     3421 tcacaattcg ttcgccattt ggtggcggtg ttcatacacc agaattgcat tcggataatt
     3481 tagaaggttt gatcgctcag tctcctggta ttcgagtagt gattccttcc aacccttatg
     3541 atgcaaaagg actattgatt tcttctatta gaagtaacga tccggttgtt ttcctagaac
     3601 acatgaaact atatcgctca ttccgagaag aagtgccgga tgaagcttac gaagttcctt
     3661 tggataaagc agcagttact cgtgagggaa cagatgtatc tattatcaca tacggagcaa
     3721 tggtgcgtga agcaatcaaa gcagcagaca atcttgcaaa agaaaatata tctgttgaaa
     3781 tcattgatct tcgtacagtt gcgccattag atgtagaaac gatcattcaa tccgtggaaa
     3841 aaactggtcg cgtagttgtt gtccaagaag cacaacgaca agcgggcgtt gccgcgcaag
     3901 tagtttctga gatctcagaa cgcgctatcc tttcattaga agccccaatc ggacgagttt
     3961 ctgcacctga tacagtcttc ccatttggac aagcagaaaa tgtctggttg ccaaatgcaa
     4021 aagatatcga agacaaagta aaagaaatcg cggaatttta agaaaagaag ggacgaaaca
     4081 aagtcatggc ttatcaattt aaattgccgg atatcggtga aggaatcgca gaaggtgaaa
     4141 tcgtcaaatg gttcgtcaaa ccaggagata cgatcaatga agatgataca ttactagaag
     4201 ttcaaaatga caaatcagta gaagaaatcc cgtcacctgt tacaggaacg gttaaaaatg
     4261 tgattgttcc agaaggtacc gtagcaaatg ttggggatgt attagtagaa atcgatgcac
     4321 caggacacga agacaatgaa ggggacagtg gtgtagccgc agaatcccaa actccagcta
     4381 aaccggctgc tgaacccact gttgatacag aatcagctgg atcgtcaagc gaaggagtct
     4441 tccaatttaa gttaccggat atcggtgaag gaatcgcaga aggtgaaatc gtcaaatggt
     4501 tcgtcaaacc aggagatacg atcaatgaag atgatacatt actagaagtt caaaatgaca
     4561 aatcagtaga agaaattccg tcacctgtca cagggacagt taaaaacgtg attgttccag
     4621 aaggcactgt agcaaatgtt ggggatgtat tagtagaaat cgatgctcct ggacacaata
     4681 gtgcaccgtc aactagtgcg ccatcagctg aagcaccaaa agaaaaagtg gaaacatcag
     4741 gttcagcaag tgtcgttgaa gctgccgatc caaataaacg tgtattggct atgccatctg
     4801 ttcgtcaatt tgcccgtgaa aaagatgtag atatctcaca agtaactgca actggaaaag
     4861 gtggcagagt aacaaaagag gacatcgaaa acttcttggc aggtggtcca agcagtgcac
     4921 cagcgaaatc agaagcgcca gaagcggcag caccgaaaga agcagctcct gcagcagaaa
     4981 gcaaaccagc tgcaccagca aaaccattca agtccaactt aggagacttg gaagaacgtg
     5041 tagcaatgac gccaacacgt aaagctatcg ctaaagcaat ggtcaacagt aagcatacag
     5101 ctccacacgt gacattgcat gatgaagtag aagtgtctaa actatgggat aatcggaaac
     5161 gatttaaaga agttgctgct gcaaatggta cgaaacttac tttcttgcca tatgtcgtga
     5221 aagctttaac agcgactgtt aagaaatacc cagtattgaa tgcatctatc gacgatgcaa
     5281 accaagaaat cgtttataaa cattactaca atatcggtat tgcaactgat acggatcacg
     5341 gactatatgt accaaatgtg aaagatgcag accgcaaagg aatgtttgct attgcagacg
     5401 aaatcaatga gaaagcaaaa ttagctcatg acggcaaact atctgcagaa gatatgcgca
     5461 atggaacaat tacgatcagc aatatcggat ctgtaggtgg cggttggttt acaccagtca
     5521 tcaactatcc agaagtagct attttaggtg taggaacgat tgcacaacaa ccaatcgtaa
     5581 atgctgaagg cgaaatcgtt gtcggtcgtg tgatgaaact gtcattaagt ttcgatcacc
     5641 gtatcgtaga tggagcaact gcgcaacaag caatgaataa tatcaaacgt cttttagctg
     5701 atccagagct attaatgatg gaaggatgat aaacaaatgg tagttggaga ttttgctgta
     5761 gaattagata cagttgtaat tggtgcggga cctggtggct atgtagctgc catccgcgct
     5821 gctgaaatgg gacaaaaagt agcaatcatt gaaagagagt atattggcgg tgtttgtttg
     5881 aatgtcggct gtattccttc aaaagcactg atagctgcag gacaccatta tcaagagtca
     5941 ctagattctg aaatgtttgg agtaactagt gaaaacgtca aactagattt tgcaaaaaca
     6001 caagaatgga aagaaaacaa agttgtccat acgttgactt ctggtgttgg tttcctatta
     6061 aaaaaacata aggttgaaac aatcgaagga gaagcgttct tcgtagatga tcacacacta
     6121 cgcgtcattc atccagattc agctcaaact tattcgttca ataacgcaat catcgcaaca
     6181 ggttcccgtc caatcgagat tccaggattt aaattcggag gacgtgtgtt agattctact
     6241 ggcggattag cattgaaaga agtacctaag aaatttgtga tcatcggtgg cggtgtgatt
     6301 ggtgccgaat tgggcggagc gtacgcaaac ttaggagcag aagtaacgat tcttgaaggc
     6361 tcaccacaaa ttttaccaac ttacgaaaaa gatctagtaa aattagtaga agatgatttc
     6421 aagaaaaaag gcgtaacagt cgtaacgaat gcaatggcga aagaagcagt cgataacggt
     6481 gacagcgtga cagtgaaata tgcagtggac gggaaagaag aatccgttac tgctgattat
     6541 gtgatggtca ctgtaggtcg tcgtccgaat acagatgata tgggcttaga acaagcgggt
     6601 gtcgaagtag gagaacgagg attgatcacg gtggataaac aaggacgtac gaacgtacct
     6661 aacatctatg ccatcggtga tatcgttcca ggggcggcat tagcacacaa agccagttat
     6721 gaagcaaaaa tcgctgctga agcaatctct ggcaaaaaag tagctgtaga ttataaagca
     6781 atgccggcag tagccttcac tgatcctgaa ttggcttctg taggtatgac gatcaaagaa
     6841 gcaaaagatg ctggtatcga agcaaaagca tataaattcc cattttcagg gaacggtcgg
     6901 gcattatcgc ttggtaaaac agaaggattc atccgtctag ttacgacgat cgaagataac
     6961 gtgcttattg gcgcgcaaat cggtggagtc ggcgcaagtg atatggtctc tgaattagct
     7021 ttagcaatcg aatcaggaat gaatgctgaa gatatcgcct tgacgattca tcctcatcca
     7081 tctcttggcg aaatcgtcat ggatgcttcg gaattagcat taggtttacc aatccatatt
     7141 tgatttgaat aatacaggcg aaacgcaact gaaaaatcag ttgcgttttg ttttttagaa
     7201 ttatcaataa tattattatg taaacttaaa aatatgacaa cttcttggtt tattaccact
     7261 tcctatgcta cactgaagag gaatatgaaa taggagagtt gaagatgcaa gaatatcagt
     7321 atccacttga tttagattgg acaacagacg aaatggtcat tgtaatgaag atgtgggaag
     7381 atctggaacg tgcgaatgaa aaagggataa acaatgaagc ttttttgaag acttatcagc
     7441 agtttaaaac tgttgtcaaa tccattggtg aggaaaaacg attgggacgg gaatttgaaa
     7501 aagcttccgg ttattcttta tatcgtacag tgcagcaagc aaaaaaaaat ccaaacaaaa
     7561 ctttgagaat gaacgggtga gataaatgga acagatgatt gatcatatca agtcctggct
     7621 tgaagaagct ggtgagaaaa tcaaatcttc tcaacaaaca ttaacaatct cgcaaaaatc
     7681 aaatcgaacg gatctagtaa caaatgtcga tcgaaacatc cagaattttc taatcgaaaa
     7741 aatccattcc tttgatccag aggcgaaaat attggcagaa gaagaagggt gtaatcaatt
     7801 atcggatctc gatggaagag tctttatcat cgatcctatt gatggcacct tgaattttgt
     7861 gattgaaggg gaaaattttt gtattatgct cgctgtttat gaatccggcg ttggaaagct
     7921 tggtttcatt tatgacgtga tgagaaatga acttttttgg ggtggaaaag gaataggcgt
     7981 gtataaaaat gatgagccat tgcctagacc agcaaataaa tccttatcgg aaggcttact
     8041 tggtgtgaat agttatcttt tcggtcataa taaatatgga atccgagaaa ttgcggaaag
     8101 cagcatgggg acacgtatgt acggatgcgc tggtcttgaa ctagtggcaa tcttgaaagg
     8161 aaaccacatt gcttatattt caaaccttag cccttgggat tatgcagcgg gaaatgtctt
     8221 attggaagag tttggtatgg taacaagcgg tctttttggt actcctttga catttgaaaa
     8281 aagggaatac tatttagcag ggacttcttg tgcatatgca gaaatcgcag accttttgaa
     8341 aaaagaaggc tgaaaaaaag gtagaaatca ttcacaaaaa tgataaaaac gagcaaaaga
     8401 ttaattttct cgaaaaaatg aaaacatttt actatatttc atgaaaaaag tctgctataa
     8461 ttagcagtcg agtaaaattt gccctgtcat aaagaaccaa taaaaaagga gttagttaca
     8521 ttgaattata gaaacgatat ccgtaacgtc gcaattattg cccacgttga ccacggaaaa
     8581 acaacattag ttgatgaact attaaaacaa tcagatacat tagacgcaca tacgcaattg
     8641 caagaacgtg cgatggactc aaatgcgcta gaaaaagaac gtggtatcac gattttagcc
     8701 aaaaacacag ctgtagacta taaaggtatt cgcgtaaaca tcatggatac tccaggacac
     8761 gcggacttcg gtggcgaagt agaacggatc atgaaaatgg ttgacggcgt tgtgttggtc
     8821 gtagatgcgt atgaaggaac aatgcctcaa acacgttttg tattgaaaaa agcactggaa
     8881 caacatatca caccaatcgt tgtcgtaaac aagattgaca aaccttctgc tcgtcctgag
     8941 catgtcgtag atgaagttct tgaactattc atcgaattag gagcagatga tgatcagtta
     9001 gactttcctg tgatttatgc atctgcacta aatggtacgt caagcttgtc agatgatcca
     9061 gcagatcaag aaccaaccat ggcacctatt tttgatacaa ttattgaaaa aatccctgct
     9121 cctgtcgata acagcgacga accattacaa ttccaagttt cattacttga ctacaacgat
     9181 tatgtaggtc gtatcggaat cggacgtgta tttagaggaa caatcaaagt aggagaccaa
     9241 gtagcattaa ttaaattaga cggaacagtt aagaaattcc gtgtaacgaa attatttggt
     9301 ttctttggac taaaacgtct agagattcaa gaagcaaaag ctggagactt gattgctgtc
     9361 tcaggtatgg aagatatctt tgtcggtgaa acagttactc ctgtggatca tcaagatgcg
     9421 ttacctatcc ttcacattga cgaaccaaca ttgcaaatga ctttcttagt taataattca
     9481 ccatttgccg gtcgagaagg taaattcgta accgctcgta agattgaaga acgtttgatg
     9541 gcagaacttc aaacagatgt atccttacga gttgaaccaa caaactctcc agatgcatgg
     9601 acagtttctg gtcgtggaga attgcatttg tctatcttga ttgaaaacat gcgccgtgag
     9661 ggatacgaat tgcaagtatc tcgtccagaa gttattgaaa aagaaatcga cggtgtaaaa
     9721 tgcgaaccgt ttgaacgcgt gcaaatcgat acaccagaag aatatatggg tagtgttatc
     9781 gagtccttga gcttacgtaa aggtgaaatg caagatatgg tccatacagg aaacggacaa
     9841 atccgtttga cattcttaac acctgcccgc ggtttgattg gttattcaac tgaattcctt
     9901 tcaatgacac gtggttacgg aatcatgaac catacttttg accaatatct gccaatgctt
     9961 cctggtcaaa ttggcggacg tcaccaaggg gcgcttgttt cgatcgatac aggaaaagca
    10021 acgacttatt ctatcatgag tatcgaagaa cgcggtacag tcttcgtaga accaggtaca
    10081 gaagtatatg aaggaatgat tatcggggaa aacagccgtg ataatgattt gactgtcaac
    10141 atcacgaaag caaaacaaat gacaaacgta cggtctgcta ctaaagacca aacatctgtc
    10201 atcaaaaaac caaaacaatt gacgttggaa gaatctttgg aattcttgaa tgatgatgaa
    10261 tattgcgaag taacaccaga aagcattcgc ttgagaaaac aaattttaga gaaaaatgct
    10321 cgtgaaaaag catctaaaaa gaaaaaataa tctgtaaaag gatgaagaga gaaaccagct
    10381 tgttataaaa aatagctggt ttcttttttt gtccaactct tttctgtgga gaagtcatct
    10441 ttgtcaatgg acataaattc agaaaatacg ccgaaagacg tttaaaagac ttttaaaaaa
    10501 cttatttcta gagagttttt gtttcataat aagataatgt ttcacgaaag gagatcaact
    10561 tgtccttcga agaaaatcga agtaaaatgg caagagaaag gagcgggaag atgaacgact
    10621 tattaaaaca atactttggc tatgatgagt ttagacctgg tcaaaaagaa attatccaga
    10681 aagtcattga tcaggaaaat gtattaggaa tcatgcctac cggaagtggg aaatcaatct
    10741 gttaccagct tccagcttta ctattagatg ggcttactgt ggttgtgtcc cctttaatct
    10801 ctttgatgaa ggatcaggtg gacgcggcga atcaattagg tatacccgcc acttttatca
    10861 atagctcgtt agatggttac gaaacagcta gacgcttcca agaaatcgat agacagcagt
    10921 accgtttact ttatatcgct cctgaacgtt ttatcatgcc ggattttatc caagcaatga
    10981 agcgatggaa cgtccgtatg atcgctattg acgaggcaca ttgtatctct cagtgggggc
    11041 atgatttccg cccaagttat ttacagatgg cgaaccagct agatcaactg ccaaatcgtc
    11101 ctgtaattgt tgctttgaca gctacagcga ctgtgcaagt agctgctgac ataaaaagac
    11161 ttttaaaaat tccagaaaac aaccatattc agactggttt tgaacgagaa aatctacgat
    11221 ttcaagtaat taaagatcaa aaaaaagaac aatatctaat cgaatattta aagatcaaca
    11281 aaaatcaatc tggtatcatt tatgcagcaa cgagaaaaga agtagaccgt ctctatcatt
    11341 tgcttaaaaa attcgatttt tccgtgggta gatatcatgg tggtctaaat gagaatgagc
    11401 gaacagaaat gcaagaagcc tttttatacg atcgcttgca gctgattgta gcgacaaatg
    11461 catttggtat gggtataaat aaaagcaatg tccgttttgt tatccattat caaattcctg
    11521 gctctctaga agcatactat caggaagctg gtcgggcggg aagagatggt ctttccagtg
    11581 aagccatcct gcttttctct cctcaagata tccaagtcca aaagtttttt atccagcagt
    11641 cccaaagaga agaagggcaa aagcaaaaag aatatgaaaa attaaaagcg atgacagaat
    11701 acgtgtatat tgagtcctgt cttcagcaat acatcctaaa ctattttggc gagacaagca
    11761 gtccgtgcaa ccgttgtggt aactgtttag atgacagaga aatagtagaa gtaacgacag
    11821 aagcacagat ggttctttct tgcttaaaac gtatgggtga gaactatggt aaacaaatgc
    11881 tgatgaaagt cttagcagga tcgaaagaac aaaagctgca agctttaggt tttggacatt
    11941 tatctaccta tggactgatg aaaaaccaat cgcaaaaaga aacgatgcag ttaattgaat
    12001 atttgatatc gaatggctat cttctgacca tcaatggtga gtatcctgtt ttgaaagtaa
    12061 cagaaagagg gatacaagta ttgaaaggac aagaatctgt ttatcgaaag gaacccaaga
    12121 aagtccagca gctatcggat gaagaaaccg atacactatt tgaagtgctg cgggaactgc
    12181 gaacggatct agcatcagaa gcaggcgttc ccccgtatgt cgtattttca gattccacat
    12241 tgaaagaaat gagccgaata cgtccatcaa gcagattgga gatgcttcag ataaaaggag
    12301 ttggccaaag caagcttgat aaatatggcg aagccttttt atctcggata aaaaatgcgg
    12361 actctaacgt tctggataag tagaaagaac gaatacgtaa aaatgaataa aaacaactgg
    12421 ttaaatctgt tttttttgct ccttatgaaa atcaaatatg ttataattaa ggaattagaa
    12481 tgggaggtaa gcacagatgg attctttgtc gaaaaaactt gcgatccaag tattaaatga
    12541 tgaagcagaa cggatcaaac gattaatccg aaatcaaaac aacagtctct gtatctcaca
    12601 atgcaaagcc ttcgaagaag tggtagatac acagatgtac ggcttttccc ggcaagtcgg
    12661 ttttgctgtc cgtataggag taatcggaaa gaacgagggc cagctgatgt taagtgagct
    12721 agaacgagaa ttgaatcagt tatatagtga ggtttaccaa gaaatttatg ataaaaaaga
    12781 agttggcaag gaggaataga cttgcctaag aaagtgaaaa aaaggcatct attagactat
    12841 agcatcttga ttccctattt aattttatgt gtattgggat tgatcatggt atatagttct
    12901 acgtcgtatc tattattaga aaacggacaa aatccgtccg catcagtcat taaccagagt
    12961 attttttggg tgcttagctt gattgctatc gcactacttt ataaaatgaa aacagatgtt
    13021 ttgaaaaacc agcgtttgat catggcagcc atcgcagttt tgacgatttt gctgctgatt
    13081 gttgtgtttt ttggtaagga gatcaatggg gcgaaaggtt ggctgcaaat tgcaggattc
    13141 tcgatccaac ctgccgaata cctaaaaatc atttctatct ggtacctgtc tctgacttta
    13201 tctaaaagac aaaacagtgt acaaaaagat tttcttggga ctgtgaaacg tccacttgca
    13261 atggttatcg gacttactgc attagtcgct attcttcccg attttggtaa tgcggcagtt
    13321 atctttttga ttattttggt tctgctttta gccagcggag tcaattatgt gtatactttg
    13381 attgtaggag taggaggctt ttgtctaagt acttttacga tctggctgat caatatcaca
    13441 aacggaaaga tcttacccgg acgtttacag tatatctata atcgatttgc tatttaccaa
    13501 aatcctttct cagacgaatt aaataaaggg catcaactag tcaacggcta ctatgccatg
    13561 ttcaacggag gactatttgg caggggatta ggtaacagta tccagaaaaa aggattttta
    13621 caagaagcac aaaccgattt tatttatgca atcgtagtgg aagaactggg agtgattatg
    13681 gggattttga tattagcgtt gctattcttt atgattgtgc gcattgtcct tgtaggtatc
    13741 cgttcaaaag atccgttcaa ttcgcttttg tgcattggga tcggcgcaat gtttttgatc
    13801 caagtatttg tcaatcttgg aggaattact ggcgttattc ctttgacagg gatcacgttc
    13861 ccatttttaa gtcaaggagg ctccagtttg ctgatgcttt cgatttgtgt cggctttgtc
    13921 ctcaacatca gtgcggatga aaaacgcaag agcttaggtt tataataaaa aaagatgtag
    13981 gagtggttcg atgaaaaaag ttttagttgc taacaggggt gaaatcgctg tacgtgtatt
    14041 tcgtgcttgt acagaattag gaattaaaac tgttggaatc tatgcagaag aagatgaata
    14101 ttccgtacac cgtttcaaag cggatgaagc atatttagta ggacaaggaa aaaaaccgat
    14161 tgatgcgtat ctagatattg aagggatcat ttctatcgcg aaagaatgcg gagctgacgc
    14221 tattcatccg ggttacggtc ttttgtcgga aaacttgaat tttgcgcaac ggtgcgaaga
    14281 agaaggcatc atttttgttg gacccaaact gcatcattta gatatttttg gagataaaat
    14341 caaagcaaaa gctgcagcta tcgaagcggg gattgcttcg attccaggca cagatggacc
    14401 aatcgcttct atagacgatg ccttggagtt tgcgaaacaa tacggttatc cgattatgat
    14461 caaggcagct ctaggcggcg gcggacgcgg catgcgtgta gctcacgatg aaaagagtgc
    14521 aagagagggc tacgaacgtg cgaaaagcga agcaaaagca gcctttggta gtgatgaagt
    14581 gtatgttgaa aaatacatcg ctaatcctaa gcatatcgaa gtacagattc tcggggatac
    14641 gcatggaaac gtcatccatc tttttgaaag agattgttct gttcagcgcc gtcaccaaaa
    14701 agtagtagaa gtagcgcctt gtgtctctat gaatgaacag caacgtcaaa aaatctgcca
    14761 ggcagctgtc caattgatga aatatgtcgg gtatgtcaac gcaggtacag tagaatttct
    14821 tgttgaagga gatgattttt actttatcga agtcaaccct cgcgtccaag tggaacatac
    14881 gatcacagaa atgattacag atattgatat cgtaacaacg caactgttga ttgctcaagg
    14941 tttggatctg cataaagaaa tcggattgcc tcagcaagaa ggaattaaat taaatggttc
    15001 agccattcaa tgccgaatca ctacagaaga cccgttgaat aactttttac cagacacagg
    15061 gaaaatcgat acgtatcgtt cacctggtgg ttttggcgta cgtctggatg tcggaaatgc
    15121 ttacgcgggc tatgtagtga caccgtattt tgattcattg ctagtaaaag tatgtacgca
    15181 tggtgctacc tttgaaacag ccattcagaa aatggaacgt tgcttgaaag aatttagaat
    15241 ccgtggagtg aaaacaaaca ttccatttat gctcaatgtc atcacacatc ctgaattcca
    15301 atcaggaaat gcaaaaacaa ccttcattga tagtacagca acattatttg aatttcctcg
    15361 actacgagac cgcggaaaca aaacgatgaa atatatcggt gaaattactg tgaatggttt
    15421 tccaggtatc gaaagtggcg aaaaaccatt ttatgaagaa ccacgtatgc ctaaagatct
    15481 aatcacaaga actgattacg taacggctaa gaatgtatta gatgcgaagg gtgccgatgc
    15541 tttggtcgaa tggatcaaag gacaggaaaa tttgttgttg acggatacga catttagaga
    15601 cgcccatcaa agtctgctag caactcgtgt tcggacaaag gatttcaagc agattgcacg
    15661 tttgactgga gaaggtcttc ctgaactctt ttcaagtgag atgtgggggg gagcaacatt
    15721 tgatgtggct taccgctttt tgaatgaaga tccttggcaa cggttgagaa aaattcgttc
    15781 tttaatgcct aatacgttgc tgcaaatgct tttcagaggt tcaaatgccg ttgggtattc
    15841 taattatcct gacaatgtat tggtggaatt tgtcaaagaa gcagcagcgc aaggaatcga
    15901 tgtatttcga atctttgata gtttgaactg gactccacaa atggaaaaaa gtatccaagc
    15961 tgtacgggat actggtaaaa tcgcagaggc agctatttgc tatactggcg atatcaacga
    16021 tccaagtcgg gcaaaataca atgttcagta ttataaagac atggcaaagg aactagaaca
    16081 actgggtgcg catatcattg caatcaaaga tatggctggg ctgcttaaac cgcaggcagc
    16141 ttatcgtttg attagtgaat tgaaagaaac gacagatctg ccaatccatc tgcatactca
    16201 tgataccagc gggaatggaa tcatcactta ttctgctgct tcaaaagcag gagtagacat
    16261 cgttgacgtg gcaatgagtg caatgagtgg gaatactagt cagcctagca tgagcagctt
    16321 gtattatgca ctggtcaatg gtccacggct gccagaaatc acgattgaaa atgcacagaa
    16381 attaaaccat tattgggaag atgtgcgcat gtattacaaa ccgtttgaaa acggcttgaa
    16441 tgctcctgaa acagaagtat atatgcatga aatgccagga ggacagtatt cgaatctaca
    16501 gcaacaggca aaagctgtcg gattaggtca tcgctgggat gaaatcaaac aaatgtatca
    16561 tactgtcaac ttgatgtttg gcgatatcgt taaagtaact ccatcatcta aagtagttgg
    16621 agatatggca ctatttatgg tccaaaatga tcttacagaa gaagatattt atgaaaaagg
    16681 cgaaacacta agtttccctg aatctgttgt gactttcttc caaggagaac tagggcaacc
    16741 cgttggcgga tttcctaaaa aattgcaaaa gattattctt aaaggcagac ctgcattgaa
    16801 tgaacgtcca ggtcttttgg ctgaatcagt cgacttcaac gaagtaaaaa aagaattggc
    16861 agaaaaaatt ggctatgaac caaaacaaga cgaagtatta agctatttga tgtatccgca
    16921 agtctttttg gactatcaaa aagcatataa tcaatttggc gatgttacat tactggacac
    16981 accaacattt ttccaaggta tacgtttggg tgaaacaatc aatgtacaaa tcgaacgcgg
    17041 aaaaacgctt atcattcgtt tagatgaaat cggagaaccc gatatcgaag ggaatcgcgt
    17101 actgttcttc aatttgaatg gacaaagacg tgaaatcact atcaaagata attcgatcat
    17161 cagtacggtc caaacccgat tgaaagctga accgacaaac cgagaacaaa ttggagcaac
    17221 gatgtctggt tctgttttgg atgtattagt gaaaaaaggc gataacgtta aaaaaggtga
    17281 tacgttgatg attactgaag cgatgaaaat ggaaacggcc atcgaagcac gttttgacgg
    17341 agaagtcgca catgtatatg tgtcttcagg agacactatt tcgtctggtg accttttgat
    17401 tgaagtgact gagaaataat aagcgaaagg tggggaaaca tgaaaagact gggtttgttt
    17461 tggctgattc tgctattagt tattgtggca ttctacatgg aaccagtctt gtttccgcca
    17521 aaacttgaag tgaaggaaaa ctctgatcaa caaatatcaa accaaatgac aacgtggaaa
    17581 taccaggagc ttaaagcaac tggtttttct acttatatcg gaaaaccgat cgatcagctg
    17641 gaaaaggatt ttggccaagc ctatgatcga ttaactagcg gatttggttt tgaaacaaga
    17701 tattatgaaa ataaagctag tcatctcaca tttgaagcga acatccaaga cagcagagtc
    17761 acaactgtta aagtactgca aacagggcct gctgatatcg cgccgtttta tttagggatg
    17821 acgatgcaag atcttacgaa aatcactact atctatacta atttcacttt tgagtaccat
    17881 gatacagaag ttggaatcga actaatggaa gaggatatga attatcgtcc gctaattgct
    17941 tttgataacg acacttttgc tattttattt tttgatcaaa caacaaacgg cctattttca
    18001 gttgtgtatt tagataaaga tagtcttttg aaactattgc catatcaagt gtttggtgaa
    18061 ggccttccac attatcaagc agataaatcg gctgattggg aatcaatcaa tcgcgttaaa
    18121 gaacgaaaaa gtacgacttt attaaatatg cttagaagag aagacgaact tcccatatac
    18181 aatcaaacac ttgcctttca aaaccacagt cagctgctac tacatgattt tttgacaagg
    18241 cctgaggaaa tattgtcaga ggaacgtatg gctgattggc aaaaatcgct aggcagtgct
    18301 caaacgacag tgaaattctc actgacgaat gatgaattgg agaagttaat cagtaaacaa
    18361 aaattagaaa atactagtgg gctatttatt catccggcga ttgacgctac tttttcgttt
    18421 ttatattggt acagcgatcc ttacaaccat gaccgtttca tggacccggg aacggattct
    18481 gtaggcattg ctttttctaa agaaaatatg ttagtcttat tgcaagaaga aaacggagaa
    18541 agtagtgata gcagtgatcg ttaacgaaga gctgtttcaa ctggaggatc aatgcctcca
    18601 agtcgctgaa atgataaaaa agagtaaaac gatggcttct tatcttgaac ataaacagtc
    18661 aatggaagaa tctgcaaaag tttgccagtt gaaagaagcg ttcttgtcta agaaagaagc
    18721 atttgaaaat gtagcggcat atggtgagta tgcacctgat tatcgtgaaa aaaaacgagc
    18781 tgttcgaaaa gcaaaaagac agcttgatat ggatgagcat gttgcagctt tccgatatag
    18841 tgaaacacag ctgcaaagtc tgttggatca aattgtccaa gtacttgccg aagaagtttc
    18901 taatgaaatc aaagtagatg caggtagccc gttttttgaa acgaaaaaac actttggatg
    18961 cggaggtaat tgtcatgcaa ttagacaata gtgaatttga aataacaaaa cgacgcgggc
    19021 tgatcgtatg ggtctacagc ttaaaacaat taaagaatct gaaaaagttc ggcttgttgc
    19081 attatgtctc aagaagaatg aaatatgtcg tgctttactt aaatgaagag acattggaag
    19141 aaacagaaga acgaatccgt aaattacatt ttgttcgaaa cgtagaacgt tcttaccgac
    19201 cggatatcga aatgaatttt gccgaaaaaa taggaaacaa aacagtatta aaagacgaag
    19261 gtttcgaaat tgaagagcta aatacagaaa tccgattagc tgaacatctt taaaaatctc
    19321 ttatgagcag tttttaaata aaaaataact tggataacga tcgatttttg atcattgtcc
    19381 aagtattttt ttggtatact agtaccagta ccatttctaa ggagtgagta gatgcggata
    19441 atatcaggaa attatggcgg gcgccgttta aaaagtttag caggggcgaa caccagacca
    19501 actacagata aagtaaaaga atccatattc aatatgattg gaccatattt tgatggagag
    19561 acagtattgg atctgtttgc aggaagcggt ggtttagcta tcgaagcagt atctagaggc
    19621 tgcagtcatg cggtatgcgt agacaaaaat taccaagcgc taaaaatcat caaagaaaac
    19681 atcgaaatta cgaaagaacc agagaaattt accacaataa aacttgatgc ggacaaagca
    19741 atcgaacggc tagcagcgga gaaacaacaa ttcgactact tgtttcttga tccgccatat
    19801 gcaaaacaaa aaataatcga tcaaatccat aaaatggaag aactgggact tttttctaaa
    19861 accgcagtta tcgtatgcga aacggataaa acagtcgaat tgccagaaac tgtggctgga
    19921 ttccatcaaa taagaaaaca gatttatggc ataacggccg taactatcta tagaaaagag
    19981 ggaaatcaat gaaacgtgca ttattcccag gaagttttga tccttttaca aaaggtcact
    20041 tagatacggt ggaacgtgcg gctaaattat tcgatgaggt agtaattggt gtttttatca
    20101 atacttcaaa gaaaagtttg tttcccccag aagaaagaat gacattgatc acaaaagctg
    20161 tttctcatct tcctaatgta aaagtcatgc atcaagaaaa tcaattgacg gtagaaacag
    20221 caaaagagat tggtgcagat gcgttgatca gaggcatacg aagtatcaaa gactttgaat
    20281 atgaacgaga gattgctcag atgaatcatc atctatatga tgaattggaa actgtcttct
    20341 tattagcaaa accagaatat agtcacgtga gttccagtat tttaaaagaa gtactgcact
    20401 ttggcggaga tgtgagcagc tacttaccgc cagtgatcaa cgaagcttta gctggaaagc
    20461 gtgaatcaaa tgaaagctaa acaatggttg aaaacagtac tgattatcat atttggaatg
    20521 ttgatcattg gatttgtagt agttcccttg ccgtattatg tagaatcacc gggagccacg
    20581 atcgatctga aagaactaat tacggtcaat gataaggaag ataaaggttc tgggtctttc
    20641 tctcttacct ctgttggtat caggcaagct acaggtttct tagctttaaa agctaaaatg
    20701 accccttttg aagaattgat cagtgaagaa gaattgactg gtggggcgac aaatgaagaa
    20761 tataatcaaa tgcaacagta ttatatggat tcttcccaaa atgcagcaat cgaacaagcg
    20821 ttaaaacttg cagacaagcc ttataaaatg gaattcaaag gcgtatatgt catgagtgta
    20881 gagaaaacat cgaatttctt tggcaagctt tcagttggag atacagtaac aaaagtagac
    20941 gggaaaagct ttcaaagtac agaagcattt atggattatg taaaaagcca aaaagttgga
    21001 caaacaatcg aaatcagtta tttgcataat ggtgaagaaa aaacagcttc tggtgatctg
    21061 atcgagttac caacagataa aaaggcagga ataggtatca cgcttactga ccataccgag
    21121 atcgaatcag atacagatgt tcgtattaat tctggctcta tcggtgggcc atcagcggga
    21181 ttgatgttca ctttagaaat ctatgaacaa gtcactggta aaaacttgcg acatggtaag
    21241 caaattgcag gaactggaac gatcaacagt gaaggagaag ttggccgaat cggaggaatc
    21301 gataaaaaag tggcaagtgc ggataaagct ggcgtagaga ttttctttgc accagatgat
    21361 acgatttcag acgatgttaa gaaagaatat cctgaaataa aaaccaacta cgaagaagca
    21421 aaagctgccg ctaaaaaatt gaattcctca atgaaaatcg taccagtaaa aacagtacaa
    21481 gaagcgcttg actatctaga gaaaatgaaa tgaaactaaa taattaaaga ggggttgtga
    21541 cacgagttct gtcacaaccc ctctttttcg tcaaaaa
//
LOCUS       DAZAOD010000045        21575 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000045 DAZAOD010000000
VERSION     DAZAOD010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.046"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            225..1217
                     /locus_tag="ACHDPO_001629"
     CDS             225..1217
                     /locus_tag="ACHDPO_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3369250.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            1277..2698
                     /locus_tag="ACHDPO_001630"
     CDS             1277..2698
                     /locus_tag="ACHDPO_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFN3369251.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            2691..4190
                     /locus_tag="ACHDPO_001631"
     CDS             2691..4190
                     /locus_tag="ACHDPO_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFN3369252.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            4229..5623
                     /gene="uxaC"
                     /locus_tag="ACHDPO_001632"
     CDS             4229..5623
                     /gene="uxaC"
                     /locus_tag="ACHDPO_001632"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFN3369253.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            5782..6465
                     /locus_tag="ACHDPO_001633"
     CDS             5782..6465
                     /locus_tag="ACHDPO_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFN3369254.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            6467..7303
                     /locus_tag="ACHDPO_001634"
     CDS             6467..7303
                     /locus_tag="ACHDPO_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFN3369255.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            7314..9068
                     /locus_tag="ACHDPO_001635"
     CDS             7314..9068
                     /locus_tag="ACHDPO_001635"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369256.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(9344..9685)
                     /locus_tag="ACHDPO_001636"
     CDS             complement(9344..9685)
                     /locus_tag="ACHDPO_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFN3369257.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(9753..11924)
                     /locus_tag="ACHDPO_001637"
     CDS             complement(9753..11924)
                     /locus_tag="ACHDPO_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFN3369258.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            12135..12992
                     /locus_tag="ACHDPO_001638"
     CDS             12135..12992
                     /locus_tag="ACHDPO_001638"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFN3369259.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(13063..13920)
                     /locus_tag="ACHDPO_001639"
     CDS             complement(13063..13920)
                     /locus_tag="ACHDPO_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFN3369260.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(13905..16607)
                     /locus_tag="ACHDPO_001640"
     CDS             complement(13905..16607)
                     /locus_tag="ACHDPO_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFN3369261.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(16620..17909)
                     /locus_tag="ACHDPO_001641"
     CDS             complement(16620..17909)
                     /locus_tag="ACHDPO_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFN3369262.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            18059..19105
                     /locus_tag="ACHDPO_001642"
     CDS             18059..19105
                     /locus_tag="ACHDPO_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3369263.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            19107..21260
                     /locus_tag="ACHDPO_001643"
     CDS             19107..21260
                     /locus_tag="ACHDPO_001643"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFN3369264.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
BASE COUNT         6381 a         4369 c         4094 g         6731 t
ORIGIN      
        1 ctctcctcct tttaaaataa aaggctttca tttttctgta aaattgatac tcatctaatt
       61 aaatgagcat tccccgcttt caagaatagc ataattaaaa ataaaaatcc aagtaatttt
      121 taacgtgtgc aatcttttca tatcaaagat ctattgactt atcgtagtta tcgtaatatg
      181 atgaatgcgt taacaaaaag tgaaaaagta aggaaaatga tggaatggta acgatcaaag
      241 atatcgctaa agcagctggc gtttctcata cgacagtttc tcgtgctttg aataacagca
      301 gtttaataaa aaatgaaaca aaacaaaaaa tacgacaact agctaaggaa atgaattatt
      361 cgccaaacta tagtgcaaaa ggtttagtga atcaaaaaaa atatctaatc ggactatttt
      421 tctcaagttt gcataaagga acttcatcaa atttcctagc agattccatt gcaggcatcc
      481 attcagtatt agacacaaat tacagtttat ctgttgaaag tatcgatgtt gttgatttaa
      541 cagaaatcaa cctgcaacgc tacgatggac tgatcgttat gagtcaaagt gatgatgatc
      601 agcctttcat cgactatctc aaagaaaaag aatttccttt cgttgttgtc aatcgtcaca
      661 tcaatgatcc agcggttatc aacgtcactg ccgatgatgc ggccggtgtt atgcaggcag
      721 tagattacgg tattggatgc ggacatacga agatcgctta tattggcgga aagaaaaatt
      781 ttcgttcgac aaaagaacgg gaaaaagggg tattgaaaag tctaaaaaaa gcgagcatcc
      841 ctgtcaatcc agcctatttt ttaacaggag attacagctt agaaagcggc ctccaaaaca
      901 tggaatacct attatcactt tctgacctgc ctactctggt tttttgcggc aacgacgaca
      961 tagcgattgg tgcattgaga gctgtacatt tagctggcct ccgtgttccc cagaacattt
     1021 ctctgatcgg gttcgatgat tctccagtcg tctcctatct caatccgccg cttaccaccg
     1081 tacgtaagcc tttgaaagaa atgtgtcaag aaggaacaaa gcttttacta gatttgatcg
     1141 aaggcaggac gatcgaacaa tctaaaattg agctctccac cttgttgatc cttcgtgagt
     1201 cgatcaatta cttgtaaact acaagtaatt ttatataaaa atgttaacgt gtgcataaca
     1261 cagaaaggaa gtttatatga aaaaactgac aaaagaatta gtgaaaaaaa acgaagcacc
     1321 tgtaaaagtt cttcagtttg gtgaaggcaa ttttatgcgt ggatttattg attggcagat
     1381 tcagcagctg aataaccaac aattgtttaa aggtaatgtt gcaatcattc aacctttaga
     1441 acaaggtctt ggaaatatga tgaaccagca agataattta tatacggtca ttttacaagg
     1501 actcagcaat ggcgaaatcg ttgatacttc cgagattatc accgtagtag aacaaatgat
     1561 caatccttat gatgaatggg atgcttatct atctctagca gaaaatgacg acttggccta
     1621 tatcgtctcc aatacaacag aggcaggaat ccaattcgtg gagactgata atttaacaga
     1681 tactccccca cagagcttcc cgggcaaact gacagccttt ttataccgac gtttcaaatt
     1741 aaacaaagct ggctttacca tcattccttg cgaactgatt gacagaaacg gcgaacgtct
     1801 aaaagaaatc attttacgct acgcagaaaa atgggattta gaacctgctt ttgttgagtg
     1861 gttagaaaaa gaaaatgttt tctgttgtag tttagttgat cgcatcgtcc caggttatcc
     1921 tcgcgaagat gcaggtgttt tcaatcaacg gcataactat gaagatcaat tgatggtcaa
     1981 agcagaacca ttcatgcttt gggtgatcga agggcctaaa gaattggaga atcaactacc
     2041 attcaaacag gctggcttga atgtcatcat cacagatgat atgactcctt atcgtgaacg
     2101 taaggtgcat ttgcttaatg gaccgcatac agcgatggtc cctcttgctt tgttggcgga
     2161 attggaaact gtagaagaag taatgaaaga tcctttattc tccgcatatg ttgatcagtt
     2221 attcaatcta gaattgattc ctatgctttc tttacctaaa gatgaattag ccatttatgc
     2281 tgaccaaatc aaagaacgtt tcttgaatcc ttttgcccat cacaaattag aagcgatttc
     2341 attaaatagt gtttcaaagt tcagcacccg tctgcttcca gtgttcaaga agtatatcga
     2401 agaacaaaat caggtaccac cgttaatcac tgtttcacta gctgcgctac ttcttatgta
     2461 tcgaggcgat caagtaaagc cacatgatga tgaaaagacg ataagcgaat ttactgatgc
     2521 ttggtctgat aatggaacag ctattcctcg attattgcaa aacgctgcgc tttggggaga
     2581 agatttgtct caaataccga atgtgacaga tacagttcaa gaaatagctg caaagatcga
     2641 tcaaaaaggt gtccggtcag tattacaaga aatgaaagga acgatggtcc atgcttgaaa
     2701 ccctgcaacc aacaatgaaa ttaaatcgac gagacagtgt ggtcgtcgca ttaaccccta
     2761 ttccaaaaca aacacaactg acgattgatc agcaaacgat caccactctt gaagatatcc
     2821 cgcaaggtca taagattgca ttgggtgatt tgaaagctgg agacaacgtg atcaaatatg
     2881 gctatccaat cggtcatgtg acgacagacg taactgccgg tcaatggctg cacactcata
     2941 atgtaaaaac caatctttct ggtgaattgg attatcgata tgaaaaagat gtccatccaa
     3001 gtcattacct ttttgagaac cgaacatttc aaggttactt gcgaaaaaat ggaaaagtag
     3061 ggattcgtaa tgatttgttt ttagtaccta ccgttgggtg tgtgaatggc attgctgaac
     3121 tgatcgtcaa acagttcaag gaaaaacatc cagatctggg acagtttgac catattacga
     3181 ttttaaagca tccttatggc tgttcgcagc ttggaaaaga tcatcaaaat actcgagaaa
     3241 ttttagcgga cgcagtaaat catcccaatg ccggaggagt tttagtattt ggattaggtt
     3301 gtgagaacaa tacagttcct gaattcaaaa aaattttagg tgaatatgat gaagaacgag
     3361 tgaaatttct agtggctcaa gatgtttacg atgagatcga acaaggtgtg gctctattag
     3421 aagagctttt aacagcggcg gaaaatgacc agcgcatatc agtcccgctc tctaagttga
     3481 atgtcggttt gaaatgcggc ggttctgatg gtctatcggg aataactgct aatcctttac
     3541 ttggtgcatt ttctgactac ttgattgctc aaggaggcag cacgatctta acagaagtgc
     3601 cagaaatgtt tggcgcagaa caagtattga tggcacgagc ggaaaatgaa gaagtttttg
     3661 actcaatcgt tgacttgatc aatgacttca aacagtattt cttgtcttac ggggaaccag
     3721 tttacgaaaa cccatctcct ggtaataaag caggtgggat cactacatta gaagataagt
     3781 ctttaggctg cacgcaaaaa tcaggaagct ctcctgtcgt tgatgtgcta caatatggcg
     3841 aaaaaatcag aaaaccaggg cttagtttat tgcaagctcc cgggaatgat cttgtagctg
     3901 cctctgctct tgcttcatcc gattgccagt tggtcttgtt taccacagga agagggactc
     3961 cgtttggctc atatgtccca acggtcaagg tatctacgaa tacaactctt tttgaacgca
     4021 aaggtcattg gatggatttt aatgcaggcg tcttattaga acaaccaatg gaagtaatct
     4081 tagaatcgtt tgttcaaaaa atcatcgctg tagctagtgg agaagaaacg aaaaatgaac
     4141 aaaatgacgt tcgagaaatt gccattttta aaaacggagt aacactttga ttttcataaa
     4201 acagtataaa aagaaagaag gaagatttat gtttttatct gatgattttt tattaaaaga
     4261 cgattgggcg aaaaagcttt accattccta cgcaaaaaac atgcccatta ttgattatca
     4321 ctgtcactta gatccaaaag aaatttacga aaacaacaat ttcagcaatc tgacagaagc
     4381 ttggttagga ggcgatcatt acaaatggcg cttgatgcga gcttgcggcg tgcctgaaga
     4441 aaaaatcaca ggaaatgctt ctgattttga aaaattttta gcttggtgtc aaaccgtacc
     4501 aaaaattatc ggaaatccgc tttacagttg gtcacatctt gaattgaagc gtttcttcgg
     4561 tattgacttg ttgataaatg aagaaaatgc agagaaaatt tggacacaag caaatgaaat
     4621 tttggcagct cctgattttc gccgtcggga aatcgcaaaa aaatcgaatg tagaagtgat
     4681 ttgtacaaca gatgatcccg cagacgactt gcactatcat cagttgcttg ctcatgaaga
     4741 accagatttg aaggttctac cttcattccg tccagataaa gcactcaata ttgaaaaaga
     4801 aggatttaat gcatgggtca cactactgga agaagcagct gaccaaacga tcaccaccta
     4861 tcaagaactg atagaagtct tagggcagcg gatagaatac ttccatcaac atggatgtcg
     4921 tgtttccgac cacgctttag acatcttacg ctataaagaa gcggatgaaa cagtattaga
     4981 agagattttt caaaaagcac gagctaacaa actattatct tcagatgaaa tcgatgctta
     5041 tcgtacagaa acactgatac atttgaccca cttctatcat tctcataatt ggacgatgca
     5101 gctgcacatc catgcttatc gtaactgtaa tacacaaatg ttggaaaaat tagggcccga
     5161 taccggctat gatggaatga atgatctttc tttgactatt cctctgcaaa aattattgaa
     5221 ccgtgcagaa gaaacggatc agttgccaaa gacgatcctt tattcattga atccgaatga
     5281 ctatcctgcg attttagctt tgatgggctg tttccaaaaa gaacagaatg gaaaactgca
     5341 gttaggttct ggatggtggt acaacgatac tcgagctggt atgcgcgatc aattgacaca
     5401 atttgctgat ggtagtgctt tggggaattt tgtcggcatg ctgacagatt caagaagttt
     5461 cctgtcctac actagacatg aatatttccg tcgtgttctt tgtgaatttt taggcgaaat
     5521 ggtcatgcga ggagaagcac ctgaagatga acaactttta ggaagtctag ttcaagcgat
     5581 tagttataca aatgctaaaa attactttgg cttttttgcc taattgatta atagtaacag
     5641 taacgaatca aaaacaggat agtgaaataa cggaatccgt ttatccacgt tttagagaag
     5701 aagacggacc aaatttgctc cgtcttcttc tcttgctgtt ctgcttcatt gcctataaac
     5761 ctttatgaaa gaagagataa catgcctact atccatattg ccggtgattc tactgcggca
     5821 gaaaaagatg aaaacaagcg tcccgagaca ggttggggag aaaaaatctc tgcttatttt
     5881 tcacccgaga tccagatcaa taaccaagca aagaatggac gcagcaccaa atcatttatc
     5941 caggaaggaa ggttagcccg tctagcttca cagtttcagc cgaatgattt cttatttgta
     6001 caatttggac ataacgacca gaaaatccaa gaagaaagag gtacgcttcc cttcggtagc
     6061 tatttaaaaa atctgcagat attttttgaa tgcgcaaaaa aagcgaacgt ccaaatggtc
     6121 ttactgacat ctgtgacgcg acgagattac ttagaaaacg gaacattgaa tccagatata
     6181 cttggagact atccaaaagc gatgcgtgca tttgctgaga aacaccatat tcctctttta
     6241 gatgtgttct caagatcaca agaattgttc cagaccttct caaaagaaga gacaaaaaaa
     6301 ttctacctgc atcttatacc tgatacttgt aaaaattacc cagaaggact aaaagacaat
     6361 acccacttta gtccagaagg cgctgataaa gttgcccgaa taattgttga attgataaaa
     6421 gaatcccgtc tgcctcttgc taattattta caaaaaggag tttgagatgt ttccattaaa
     6481 tttaggcatc cgtgcccacg atttagatgt tcgaaatcgt gaagaaatcg ttcaaaaagt
     6541 atcacagctt cacttgtccc atatccaatt tgcaccacaa aaagcatttc ctgaacaact
     6601 taaattaact gacatgacac ttgggagtgc tgcctatttt ggtgaatact tccaaaaaaa
     6661 caatatcgaa ctttccattt taggatgcta tatcaaccta tccagcaaaa atcaagaagt
     6721 tcgtgcacaa gcattggcaa ctttcaaaca gcaaattgct ctgtgctctg cctatcaagc
     6781 caagatgatt gctacggaaa ccggtagtgt ctctgtcggt tacacaaaag aaaattttac
     6841 tgaagaagct tatcagatcg ccagaaattc tatcattgaa ttagtcgctc atgcagaaaa
     6901 ttttggcgta actgttgctg ttgaagcagg gatcaatcat ccaatctata actatcagtt
     6961 agctaaacgt ttaatcgatg aagtagcttc accaaattta aaaatcattt tagattgtgc
     7021 gaatttgatg cataaagaaa atcatgctga tcaggaaaaa gtgatccgag gtgccttgga
     7081 caatttacat ggttatatta cagcgcttca tctcaaagac tatatcatgg aaaatggaaa
     7141 gatccgcatg gtacctgttg gcaagggctg tttagatttc cgcccggtac tgcattatat
     7201 caaatatgag cgtcctctaa tgtacgccac tcttgaagct actcctgaga tttatgttcc
     7261 tgaagcaata gaacacttgc agtttattta ccaagattgt taaggagaag attatggagg
     7321 aacgaataca gaaaagttat caaaaatatc atgcaaatgc ttttcagaca ttgctgcatc
     7381 tttatcaggg aaattattgg cgttttgcca tgtcaggact cttttttatt atcaaacatc
     7441 ttccatcttg gttaatgccg atcgctattg ccaatgtaat caatgcagct tcatcgaaag
     7501 attcttctca gttgcaggcc atttatttca acgctttttt gatggcttgt ctgattggtc
     7561 aaaatatatt gacgaattat tttcatgtaa aataccatag cacttcgatc cgtcaagtag
     7621 aagctggact aagagcgacc cttatcaaga aaatccaaga actatctatt ccttatcaaa
     7681 aagaattgca atctggacga atccagtcaa agatcatccg tgatgtagaa gctatccaaa
     7741 cgttgtcctc tcaagtattt gtcagcggat taaatatcgc tgtcaattta ttcgtagctt
     7801 taggtatcac gctttataaa agtcctgttg ttttcatgtt tttcttattg actgttcctc
     7861 tcgccgcatt cgttactctc tttttccgta aaaggatcag acagtccaac tcagacttca
     7921 ggcaagaaat ggaagagact tctgcaaaag tgatcgaagt gatcgaatta gcaccgattg
     7981 ctcgagctca tgggttagaa aaacacgaaa caactcgctt aaataagcat tttactcaaa
     8041 tctatgaaaa aggattccac ttagatatcc tgcaatctgt tttcggatca gtcagctggg
     8101 ctagttttca gatatttcag ctgatttgtt tgattttcac tgggatatta gctttacaag
     8161 ggcgcatcca acccggcgat gtcgtgatgt atcagacgta tttcacgacg atcgtcaatt
     8221 ccgtttctgg aatgatcacg ctgattccta cgatttcaaa aggcatggaa tctatcactt
     8281 ctattggcga actgttgatt gctggcgatg tagaaactta tcacggtaag aaaaaaatcc
     8341 aacatttgga tggaaatttt cgttttgagg atgtttcttt tctttatccg gactcactca
     8401 aaccgattat cgatcatttt tctctagagg tgaaagctgg agaaacaatt gcttttgttg
     8461 ggccatctgg ctctggaaaa tctacactcc ttaacttatt gattggattt atccagccga
     8521 cttcaggaaa aatttttcta gatgatcagc ctttggatga actggatatg cgaagtgtgc
     8581 gaaattattt agccgttgtt cctcaaacca ctttgttgtt ctccgcttcg atcaaagaga
     8641 acatcactta tggcttgaaa aacgtatcaa aagaacgttt agatgaagtc atcgaagctg
     8701 cgcaactttc ttcactgatt gaccagcttc ctgatggtct ggatacctta gtaggcgaac
     8761 atggcaacaa gctgtctggt ggccaaaagc aacgtatctc cattgcacga gcgttgatac
     8821 gtcagccaaa aatcattttg ctagatgaag caacctcagc tttagataac cagtcagaga
     8881 aaaaaatcca gcaagccctg aattacctga cagaaacacc cactactttt attgtggctc
     8941 atcggctttc aacgatcaaa gaggcagata aaatcgttgt gatcgatgaa ggaaaaatcg
     9001 ttgaaatagg tacttacgaa aaactgttag ctcaaaaagg ctatttctac cgcttgaaaa
     9061 atgaatgaca aaaaatagga gctatgacaa gacttttgtc gtagctccta tttctgaata
     9121 aacggtgttc tcctgccaac tcctcggtca caagtcacaa tagtcatcaa acatgagaag
     9181 ctgttttttg aaattgttcc ttgtaactca gagttaaacg gtaggctcac gacctcttgg
     9241 taaatggtgt tcaagagaca gcctatcggc aataagaagc aattttgtca tcgctcaagg
     9301 ccgaacgtct ctttcacacc ctctgttgtt tcataaaata gttttattcg ctgtaaaggt
     9361 cgcgaactgg tgtcatgatg atacggttca agtcattgat gattgtactg aagccttgct
     9421 ctttttgcat caagtcattg attacttctt ctgattggat tttcacagcc atttcttgtg
     9481 ctttcattgc atcttcgtcg ctgaactctt gtccactcat ttgtttttct tgtaattcga
     9541 tttgcatcgc ttggaagtct ttgaacagtt tgtgtgcttc ttcgtttgct tgtactttct
     9601 cgtacgcttc tttcaacgct ttgaattctg gtaattcacg gatctcacgt tcgatttgat
     9661 tcgcgctatc gtagatgttt gacatgttat gccctctttt cttttagtag ttactctcta
     9721 ttgtaacatg gggttattcg ttttcaaagg ggctactctc cttgatattt ccgccagagg
     9781 tctttagccg cttcaccaat tccctgaacg ccttctttca ccatatcgcc gaagtttttc
     9841 agcccttctt ttgcttgttc accatattga ttcaagttat cttgccaatt tccagactct
     9901 ccattagaat ttcctgtgtt tccaacttga tctgcagcta ccacttgtcc tcctgtggca
     9961 taggcatctg ctacactaaa tcctgttttt gaagtatacg gaaggatgcc ttctgccgct
    10021 gatttgaaga ctttcccgac aacatttcca cttgtccctt ccaaatagtg cagcttgctg
    10081 gattcttcgt aacccatcca tgtcgaaatc actacgtctg gcgtgtaacc gatcatccat
    10141 tggtcatttg cttttgtggc atcgaaatta gtttctgtgg ttcctgtttt ccctgctatc
    10201 gtataacctg caggattcgc agcagccgct gttccatttg aaaatgtacc aagaagcatg
    10261 ctggtcattt catcggctgt ttcctttgat atgacctgtt ttggtttttt gtttgtgtta
    10321 tcgacgatca ccgctccagt cgaatcaacg attttcgtga taagatgcgg cgtatacatc
    10381 tgaccatcat tggcaaatgc actgtaagca cccgccatga tcaatggaga tactcctttt
    10441 tccagtccac caagggctaa gccataatac ttatcagatt ttgctaaagg caggccgaat
    10501 tcttctgctt tatcatatcc tttttgtaaa ccgatctcat gcaaaagcca tacagtaggc
    10561 aaattcaaac tttgtgcaac agcttgatac atcggtactt ctccttggta tgtcccgtca
    10621 aaattatgcg catcgtaata actttgcggt tcgtctttca agatactgga aggcttgtat
    10681 ccagcttcca gtgctggtgt atatacgctt aatggtttga tcgttgatcc tggtgaacga
    10741 cgcatctgtg tagcaaagct gaatcctcta aagacatgat ctcctcttcg tcctactagt
    10801 gcttgtacac cacctgtatt cggatctaaa gctactgaag cagattggac catggcacca
    10861 tctgaagcat ttgctgggaa taatgcactg ttttgataag tagcttctaa ttgcttttga
    10921 taatcctgat ctaaagctgt atagatttta tagcctttat tcatgacatc ttcttcatca
    10981 agaccatact cgttaactgc ttcatcgatc actgcatcaa aataataagg ataacgataa
    11041 ccagaatctg aattatcgta tgtgtcatta agatacgcgc tgatatctgt ctggctttct
    11101 gcttgttctt gttcttttgt gatttttccg ttttcttcca ttacacttag tactgtgttt
    11161 ttccgatcat tcgcattttt tgggtgatcg atcggattat aaataccagg acctttcagc
    11221 attcctgcca aagtagcagc ctcagacagc gtaacattcg ttgcatctac tccaaaatac
    11281 tttctggaag cgtcttggac accccatacc ccgttgccaa aataggcatt gttaagatac
    11341 atggtcaaga tttcttcttt gctgtacttc ttttcgatct cgattgccaa aaataattcc
    11401 ttcgcttttc gatcaaacgt ttggtctaat gtcagatacg catttttggc aagctgctga
    11461 gtgatcgtac ttcctccgcc ccctgatgtt ccgccagaca agaccattcg gactgctgca
    11521 cgggcaatcc ctttgatatc aaacccgtga tgctcgtaaa aattcctatc ttctgtcgag
    11581 attactgcat cttggatata gggagaaatc gcgtttaatt ctacatatgt tcctttttgg
    11641 gcgtacagtg tgccagcttc ttcgtttttc ttatcataaa tgactgtcga ttggcttaat
    11701 cctgatttta acgtttcgac atttgcttgt tttgctaaaa taaagaggta gatacttgtc
    11761 actaagacac agatcaaacc aatcagcaaa atcaatttgt tcacatgata ttttttccag
    11821 atgcgctttc gccatcgatg gaattgtccg agatatggtc tgatccaacg ccaaaaactg
    11881 atcaaagcag cttttatctt ttctaaaatg ctttgaaaat ccatttgctt cttctcctgt
    11941 ctatttgatt caatcgtctt attttaccat agtgaaagag tgttttcttc ctgcttaagt
    12001 tgtagttcaa tatgtttttt tacgttagtg caagtagagt aacataagaa tgaacagaaa
    12061 aatgtaagtt ttttcttaaa tatgttttaa aaatggtaca attagtctgc gattgcactg
    12121 aaaggagtac acttgtgaaa atcacgatca ctttacctat gaaccatcct gaaacaacaa
    12181 ttcgcgactt gcttgaaaag gaatggttag ttcctagaaa ggttcgacac tttttgcgta
    12241 tacgtaaaaa cgtttggatc aatcaacaac ctgctttgtt ccatcatgaa gtaaagggca
    12301 atgaccagat cacattgtta ttcgaagaaa cagattataa ttatcaagaa gttcaattag
    12361 gagatgcgaa gcacatccgt gttttatatg aagatgagca tttgattata gtggataagc
    12421 ctgcaggaat gaagactcat ccaaatgaac cgacagaaaa cagtacctta ctcaatcatt
    12481 tagctgctta tctcgacact aaacagcaac gaccttacgt tgtccaccgc ttggacaaag
    12541 aaacaagcgg tgccgtttta tttgcaaaaa atccatttgt cttgccgata cttggaagaa
    12601 tgttggaaca aaaaatgatc tatcggagat atcaagccat cgtatgggga gaaattgcca
    12661 aagatatgac catcaccaat aaaattggac gagatcgcca tgatcggaga aaaagggtcg
    12721 tagatgataa aaatggtcag agcgccttga cacatgtcac tgtcaacaaa gtactttctg
    12781 aacaaacaca agtctattgt gttttggaaa ccggacgtac acaccagatc agagttcatt
    12841 tagctcataa gggacatccg atcgttggag accctctcta ccaaaataga acagctgaac
    12901 gactgatgct ccatgcatta gaactgcaca tgatccatcc atttactcaa gaaaaaatag
    12961 tcggtaaagc tttacctgga ttatgggaat agaaataaaa aagaacagag tcttatcagc
    13021 agataatgat aagactctgt tctttttgtg taatttgtct gcttactttt gatgttcgtg
    13081 ttctgctaac agcaaactac cgataatccc actttcattc ggcagtcccc aacgaacgat
    13141 atattcactt acttgaggtg tttccatata accacccatc aattcaacaa attgctgacg
    13201 gattttttga aggagatgat cctgattcat taccccaccg cctaaaataa tcttttcagg
    13261 tgctaacgtc aacgtatagt tgatcagtgc ttgagcaata taataagcct gaatagccca
    13321 aacaggatga tcttgcggca gatcttgccc tttgatccct gtgcgtgcct caatagacgg
    13381 tcctgctgct aatccttcta aacaatcttt atgataagga caagtacctt cataatggtc
    13441 atctggatgg cgtttcaccc aaatatgtcc catttcagga tgtgcgatcc ctgaaaaaat
    13501 ttcttcattg atcacgacac ctgcaccgat tcctgttccc acggtaaggt aaatacaact
    13561 attttttcct tgtgctgctc cttgcttcaa ttccccatat gcagcagcat tgacatccgt
    13621 tgtccaagca gcaggaatat tgtagcgttc cttgattgtg ccaagaaaat cgaattgtgc
    13681 ccaccctttt ttgggagttg ccaaaacgta tccgtaatta tcttttgttt tgtcgatacc
    13741 aatcgggccg aatgagccaa tcccgattcc cttcaattca taacgatcaa aaaattcaaa
    13801 tacctgatcc aatgtttctt ctggtgttgt ggtagggata cttaattttt ctaaaatttc
    13861 tccaccatct gaaaccgcac acacaaattt tgttccgcct gcttctattc cgccatacat
    13921 tcgttttcct cctcgaatcc gattgtccga atctcataag gttggattat tgggacaacc
    13981 gcttgcttcg ttggttcttc aagcagattc aatatgacag tttttccatt gtctttagtt
    14041 atttccaatt tttctaaatg actagacata ttgaaacctc ttactactac tttatcacta
    14101 aacttgctgc gtttcaaagc tgtaattgca aacgtttcac tttttatcgt taaatattgt
    14161 tgttttgaaa tcaatgttcc ttcatgatgt ttgatttgtt gagtggaaaa aggaatctgt
    14221 gctgcgtatg catgcaaata agtagagaat ttttcttctg gtccatgtag ttcaatgctg
    14281 taattgaacc gatgctcacc tagacactgt gcttctggtg ttggaaaata tccccaatcg
    14341 cctagttctc ccacactgcg aagtagcgtc actgcgattt gtccgtcttc tgttacttca
    14401 tattcattca aaccaaagtt tccgactgtt acaccgtact cttcatcatg aatattgaca
    14461 aatgcttgct gatgttgcgg attcgtgggg ttttcccaac ttttagacac atggtttggg
    14521 cgcttcacca cttcaaaaat actatctgct tcgtgatgtt ccacatgtaa ctttgtagga
    14581 aacaagacac gtaagcgatg atctttcatc tgattgtcga gagtcgtttc aaagtcgatt
    14641 tttttactat cttttctgat tgtcatgatt gtttttattt gaaggattcg tttttctttg
    14701 gatcgttctg cttttcgata acgaaattcc acaaccatct gctgttcttt ttctaaacgc
    14761 tcgtctgcag aaacagggat ttccatttcc tgtagaatac ttatttttgc tatttccggt
    14821 gtatctacta atacttttac ttcagagttt tctttgttac tggataggat tggctgatca
    14881 cagaaaggtt gtttaaagat atactcattt cctatatcgc cgatatcttc aaaaatatgc
    14941 agattattca actttcgttt gtttttgcga tcttccattg taatggtacc atttttttca
    15001 atcgtcaaat gtagagggcc gttttcgatg attcgtccac tctgatgaat cattgtttcc
    15061 ttttcttctg ctttcgcttc cccttctaca agcgcgaatg tttcccaaga aaatgctggc
    15121 atgttttcta atggtaaagt cactttgatc attcttgcca tatatggcac acggaaacgg
    15181 tctttcggca aatcataacc aaattggaca gtttcttcag ataaaatagc tggtatagtg
    15241 gccccacttt ttgtttctac atgatactta cgtttaggca aattttctaa ctcttgatat
    15301 agttgttcag gtattccttc agcgaatctt tttctttcta attcgatggt tatttctgct
    15361 tcaccagttt tatccattcc tgcagtattt acaatgacaa atggaaagct gtcttttggg
    15421 aatccggtcg tatcgattgc tgcggtcagc tgttctaagg aatcttgtgc aagatacttt
    15481 ccaacttcat ctgctttttc aaaacgaggt atcatttccc gatggacaga atcgactgaa
    15541 caaccgcaaa tactgtcgtg aggatgattt tgcattaatg tcttccaagc ataatctaat
    15601 tgatcatggg gatagtttcc actaacttca taagccatcg tcgcaagtgg ttctgtaata
    15661 ttttctagct gtcgctggac cttggtattc cattgtttta agtaaacccg agcagatgct
    15721 gtattggcta aagtatacca gccatccgtt tcttgacttg tcaattctcc ttctactgag
    15781 cctaagtctt ctggcacatc tttttgaact gcttccagat agtcagtaaa attagaatga
    15841 ataaactcgt aatctggaaa cagttcattt gcgagatgga ttgcttttga tatatctttt
    15901 tgtaccggtt gatgatcaac accattcatc atcaataagt ggttcgtaga ggcatattgt
    15961 tctgcatccg ctaatttttg cttccaaaag gcaagagctg cttctttttc tactggaatc
    16021 tcattcccgt tgctatacca attggcaaat agcagaccaa agattgctgt ttgatcaggg
    16081 cctttccacc acatctctga gtattgggaa gaatagtttt ctgcttccaa aacttgatta
    16141 tcaaagccaa ttggttttac accacggcca aacgctgctg ctgaaatacc agcttgtttc
    16201 attaattgag gcgtctgtcc catatttcca aatgtatcgg gaaaatagcc taacatgaca
    16261 ggggttcccc atttacggct ttcttccatg ccaatcagca tatttctcac gttcgattcc
    16321 gagctgataa gaaaatcatc ttgcaagata taaaatggtc caattctcaa ttttccttca
    16381 ttgattgctt gttggattgc ctgtcttttt tctggcctta cttgaagata gtcatctaaa
    16441 ataatcgttt gcccatccaa atgaaaactg ttgaaggacg gatcaacttc aaatagctct
    16501 agtagatcgt ctatcaattc aatcagtcgc atgtgatgct gttcgtaagc catgtaccat
    16561 tcacgatccc agtggctatg agaaatgata tatactttct ttttcattta cgatacctcc
    16621 tacttttcta ctctaatatc aaagtaatcc atgactaatt cgcaaaacat catatttgcc
    16681 caagaaaacc attctctcgt ataattttca ggattgttca catcgaatcc ttcgtgcata
    16741 aggtgtgttc ctgcgtcagt tgctacaagt aaattcaata tccgctcttt ttcagatttg
    16801 tctgacgttg tcattccttc catagctaat gcaatcggcc aaacgtattt ttctggcgta
    16861 tgggaggatc caattccttt tgcgtacttt ccttcataga aatatggatt ttctttactc
    16921 aacaatgttc ttcttgtttg cagataatct tcctcttgtt cagaacaata tcccaagtaa
    16981 ggtgcggcga tcagattggg cacattactg tcatccatga ctgtggcgtt tcccattcca
    17041 tctacttcat atgcataaat cgtttgccct ttttgattaa ccgttcgtcc gtgattctga
    17101 atcccctctt ggatctcttt cttcaatttc tgtgtttgct gtacaatttc tttatcatcg
    17161 agtatcgttt gaaaaatttc ttccacataa cctaacacga ccaccgcaaa catattggat
    17221 ggtaccagat atccataacg gcaagcatca tcgctaggac ggaaaccaga ccatgtcatt
    17281 cctgtaaaag ctgtttttgc acctcgcccg tcattgatca gcgtatcttc ttttcttgtc
    17341 gtgtctcgta caaatgtata aggagagtgt tcatgatctt gctctgtttt gaacacgtcc
    17401 aagatttttt tgataccttc aataaaagat tgattgaatt gatcagtttt tcctgtattt
    17461 ttgtaaagaa gataggccaa ctgtattggg tagcataaag aatcaatttc atattttctt
    17521 tcccagatcc aatcgttcat ttttgtatga tctgtttggt ggccagcacc gttagcttct
    17581 tcgttgaagg cattcgcata tggatcgata ttgatataaa aaaattgctt tttgactaac
    17641 ccgctgatca tgtcagctaa ttcctcatct tcttttgcaa tcactaaata aggacgaact
    17701 tgtgcagtag agtctcttaa ccacatcgct ggaatgtctc ccgtcaataa aaaggtggtt
    17761 ccgtcatttt gctttttgac tgttgtcaac agagtattgg caaatgctgc tgtaaaattc
    17821 tttgcccagt ccgcatggat atccccacat ttttgtgtga tatcttccat aaatttctgc
    17881 accgattttg gtatatcttt ataaaccact aataaaacct tctttctatt tgatatatct
    17941 ttaaagatta tacttcatac agccaattat gtctacgctt tcaaaaaata tctttttatt
    18001 tactttttca tccattatgg tattatttga atatgatata tcattaagag gtgtttatat
    18061 gactcaacca ttgtaccaga caatatttaa tgatttgcaa acggctattt taactggtga
    18121 attacctgta gacagccaac taccaactga aaaagaactt tcacgtacct ataaagtaag
    18181 cagaatcact tccaaacgtg cattgactga attagagcaa ttaggactta tttatcgcgt
    18241 tcgcgggaaa ggcagtttcg ttaaatccgc ttctccggaa cagattcttg cttctcctac
    18301 aaaaacacga cggattctgt ttcttcttcc atatgtcgct gatttgtctg ttggtgattt
    18361 tagcaaggga ttgaaccctg tgatgcaaga taaacagatt gatgtcatga tgacgacgct
    18421 tgactttcta caaaataaaa cagcaaaaga gctaatcaat gaatttgacg gattgattta
    18481 ttatgctctt gatacagaac aacatcttga cttacttttt gagctttcat tgaaagaatt
    18541 ccctgtcgtc atattagata aaaaaatcta tgagttacct tttcctaccg ttctttccga
    18601 taatttccaa ggcggtgcgc ttgctgcctc ttatttgatc gaacagggac attcaaaaat
    18661 cgcttatttg tttggtacgc agactcatcc acaatccgtt cgacagcgtt accttggtta
    18721 ccttgaagca ttggacaaag ctggtttgac tttccacact tcactggatg acaaaagcgc
    18781 gacattagat gaattgcttt cttatatcac taagtatgaa gtaactgctt ttgtttgtga
    18841 aaacgatgtt gtcgctatcc agaccatgaa tctcttgaga cagcatggtt atcatatccc
    18901 tgaagatttt tcaattatcg gatttgatga tatccaagca gcagctcttg ttgacccgcc
    18961 actgacaacc atcgcacaag attttgaaca gttaggtaag cttgcgggag atgctttggt
    19021 cacttggtta gagacaaaag atcgaccatc cgatagtaaa tttccagttt cattcatcaa
    19081 aagacaatca acaaaggaga aataaaatga atatcggtca aatagatact agacatgcaa
    19141 cagcgaatca gccaaatttc tctaatggga actgccagcc ttatactggc gttccttttg
    19201 ggatgaatta ttttgcaccg caaactacgg atcaaaacgg cagctggtgg tttcatcctg
    19261 atgaccgcgt ttttcaaggc taccgtctta cccatcaacc aagtccttgg atgggtgatt
    19321 tcagtcatat gctgtttacg ccgatcaatg gaaaactaca ggagaacacc cttttccatg
    19381 ctcaaagttc ttaccgccca gaagaaagta tattttgccc gactcatctg tcgatctgtc
    19441 aattacgtta tggcatctgt tctacattga tacctagcat gtatggcgga atcttatcta
    19501 ttgattacag caaaaatgac agcggtttac ttttatcctt tccgggacgc catcagctct
    19561 ttgttataga tccttacaca gtggaaggaa aaatcacaca ttttgctggt tcagaagatc
    19621 ctgatttttc tttttatttt atattgagat ttgaatatcc tttaacaatt gatgagttag
    19681 ctgtttccaa caaaaatagc gactcgatcc cgttgtattt tgaacagaca aaaaaacaaa
    19741 ctatccgatt tgggacatct tttatcagct cggaacaagc agcttataac ctggaactag
    19801 aacaaaacca aagcaaagag acttaccttg ctcacagtca agaacaatgg cagtcctatt
    19861 ttgatcgtat acagctcaca caccatgatc aacaacaatt gcggacgttt tatcataatt
    19921 tatatcgggt gtttttattt ccacaaacat tttatgaaat tgatcctagt gggcaaaaaa
    19981 tccactatga tacgactagt cgatctataa aacctggtgt tctctataca aataatgggt
    20041 tttgggatac gtataaaacg gtttatcctc tttattcttt gattgctgta gaaaaatacg
    20101 aagaaatgct ggaaggtttt ttgaacagct atagagaaag tggctatttg ccaaaatggc
    20161 tgtctcctga tgaacgtgga cttatgcctg ggacattgat cgatgcggtc attgcagatg
    20221 ctgctgtaaa agatatccga cgagacttga tgcctgaatt tctaacggca atggaaaaag
    20281 gtgctacggt tcaaagcaaa catccaaatt atggacgcca aggaacagaa gattacttga
    20341 catatggcta tgttcctaat cactaccacg aatcagtcaa tcacacatta gactatgctt
    20401 atagcgattt ttgtattagc caagttgcca aggtactaga agaagaggaa atgacgaaga
    20461 aatatcagca gcaatcattg aactatcaaa atatctttga ctatgagtca ggatttatgc
    20521 gttcaaaaga taaagatggc aagttcagag aaccattttc agctaatcgt tggggacaag
    20581 attatgcaga aggaagtgct tggcaaagca gctttgctgt ttatcacgat ttttcaggac
    20641 tgatcggaaa atatggtggc agtgagagat ataaagaaaa actcattgag ctgtgcaatc
    20701 agcccccaac gtttgaccca ggaggatatg gttttgagat ccacgaaatg agtgagatgg
    20761 ccgcgataga atttggacaa ttagctattt caaaccagcc aagttttcac tatccttact
    20821 tgttcagtta tataggacaa cctgaaatgg cacagccact gcttaaacag ttgatgactc
    20881 agaccttcga cgattctcca atgggttacc ctggagatga ggacaatgga agtatggccg
    20941 cttggtatat cttcaatagt ctgggatttt atcctgtcac gcctggaacc ggtgaatatg
    21001 ttatcggtat gccattaatt gacaaggctg ttttgctttt gtcaaatgga aaggaattga
    21061 cgattgaagc aacgcctaat cggccgcagc aacaatttat ccataaaatc aaacggatgg
    21121 acagagaata tacgaaatta tattttaccc atcaagattt gctgaaaggc ggcacgatct
    21181 cttaccaatt agggatcatc cctcacccta agaaatatca agcaaaagat ttgccttttt
    21241 ccttatcaaa ctataattaa caagaggttg tgaaaaagct gtcctgcatc aagtaataag
    21301 aacagccaag caaaaataga tcctcatatt tttcgtttgg ttggtcttat taccgcagat
    21361 gcaagctttt gaacaccgtt tattgagagg ttgtgaaatc agcgttctga cctgagtatt
    21421 agagagacaa atggcaaaat agttcctcat attttgccat tttttgagct aataccgagg
    21481 gtcagctgat tgaacaccat ttagtggaga ggtcgtgaaa aagctgttta gtttcgagta
    21541 ttaagaaaaa ttttgtgaaa atggctttcc acatt
//
LOCUS       DAZAOD010000046        20989 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000046 DAZAOD010000000
VERSION     DAZAOD010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.047"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            654..1343
                     /locus_tag="ACHDPO_001644"
     CDS             654..1343
                     /locus_tag="ACHDPO_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFN3369265.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1330..2538
                     /locus_tag="ACHDPO_001645"
     CDS             1330..2538
                     /locus_tag="ACHDPO_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFN3369266.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2832..4103
                     /gene="serS"
                     /locus_tag="ACHDPO_001646"
     CDS             2832..4103
                     /gene="serS"
                     /locus_tag="ACHDPO_001646"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFN3369267.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4652..6136)
                     /gene="guaB"
                     /locus_tag="ACHDPO_001647"
     CDS             complement(4652..6136)
                     /gene="guaB"
                     /locus_tag="ACHDPO_001647"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFN3369268.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6641..7336)
                     /locus_tag="ACHDPO_001648"
     CDS             complement(6641..7336)
                     /locus_tag="ACHDPO_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFN3369269.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7426..8526)
                     /gene="ychF"
                     /locus_tag="ACHDPO_001649"
     CDS             complement(7426..8526)
                     /gene="ychF"
                     /locus_tag="ACHDPO_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFN3369270.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8535..8726)
                     /locus_tag="ACHDPO_001650"
     CDS             complement(8535..8726)
                     /locus_tag="ACHDPO_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFN3369271.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8747..9637)
                     /locus_tag="ACHDPO_001651"
     CDS             complement(8747..9637)
                     /locus_tag="ACHDPO_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFN3369272.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9624..10391)
                     /locus_tag="ACHDPO_001652"
     CDS             complement(9624..10391)
                     /locus_tag="ACHDPO_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFN3369273.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10403..11116)
                     /gene="rsmG"
                     /locus_tag="ACHDPO_001653"
     CDS             complement(10403..11116)
                     /gene="rsmG"
                     /locus_tag="ACHDPO_001653"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFN3369274.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11348..13249)
                     /gene="mnmG"
                     /locus_tag="ACHDPO_001654"
     CDS             complement(11348..13249)
                     /gene="mnmG"
                     /locus_tag="ACHDPO_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFN3369275.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13266..14663)
                     /gene="mnmE"
                     /locus_tag="ACHDPO_001655"
     CDS             complement(13266..14663)
                     /gene="mnmE"
                     /locus_tag="ACHDPO_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFN3369276.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14962..15345
                     /locus_tag="ACHDPO_001656"
     CDS             14962..15345
                     /locus_tag="ACHDPO_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369277.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15513..16271)
                     /gene="jag"
                     /locus_tag="ACHDPO_001657"
     CDS             complement(15513..16271)
                     /gene="jag"
                     /locus_tag="ACHDPO_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFN3369278.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16289..17107)
                     /locus_tag="ACHDPO_001658"
     CDS             complement(16289..17107)
                     /locus_tag="ACHDPO_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFN3369279.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17104..17460)
                     /gene="rnpA"
                     /locus_tag="ACHDPO_001659"
     CDS             complement(17104..17460)
                     /gene="rnpA"
                     /locus_tag="ACHDPO_001659"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFN3369280.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17578..17712)
                     /gene="rpmH"
                     /locus_tag="ACHDPO_001660"
     CDS             complement(17578..17712)
                     /gene="rpmH"
                     /locus_tag="ACHDPO_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFN3369281.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18235..19569
                     /gene="dnaA"
                     /locus_tag="ACHDPO_001661"
     CDS             18235..19569
                     /gene="dnaA"
                     /locus_tag="ACHDPO_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFN3369282.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19767..20897
                     /gene="dnaN"
                     /locus_tag="ACHDPO_001662"
     CDS             19767..20897
                     /gene="dnaN"
                     /locus_tag="ACHDPO_001662"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFN3369283.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         5999 a         4275 c         3845 g         6870 t
ORIGIN      
        1 tcaagacgcc ctacacattt ggtttgtctt actttgttca gttttcaaag gtctacttca
       61 tcaggagtgt ttcccgattc gtttttggct gccgtagcaa cttttatatc atatcagaga
      121 gacaagtaat tgtcaactct tttttaaaag ttttttcgat ttcgtttttc gaaatcttcc
      181 agcaactcat ttatcataac ttatcgtttg ttatttgtca agaacttttt tgaagttttt
      241 ttcgatagaa tcaagcttcg caagtggttc ttttttaacg actcagttat cttatcatgt
      301 catttccaac atgtcaacaa cttatttttt attatttaat aagttattgg tgttcttttg
      361 aacaaataat aatatatcaa catcacatgt gaaagtcaat aagaaaatgc ttatttatca
      421 acatttctag cttacatgat cattggttag ttctggtcct ttttcgttcg tctttataac
      481 tccgagagac gtaaaatcct tttgttttca gtttaatgtt catgttcttg tcttattcac
      541 accaactaga tgtctcacct tctaaaattt tccttaacaa agtgctgctt ttatctattt
      601 ctgctttttt ttgctagaat aatagtaaca atatgactct ggaggattta tttatgaaaa
      661 ttttgattgc tgacgatgat aaagaaatcg ttgaattatt aagtatctat gttcacaatg
      721 aggggtatga agcagtaaag gcttatgatg ggaaagaagc attatctaaa atcagaacaa
      781 tccctgatat tgaattactt attttagata tcatgatgcc tgagatggat gggatgcaag
      841 tagtgaaaga gctacgaaaa gaatcccaaa taccaatcat tatgctgaca gcaaaaacta
      901 ctgatatgga taagatcaaa ggactggtcg ctggtgcaga tgattatgtg accaagccat
      961 ttaatccgtt agaagtaatg gctagagtaa agtctttatt acggcgtaca aaaatgcaga
     1021 ttgccccaga tcagcctgat gtattagaag taaatgcatt aatcatcaat aaagactctc
     1081 atgaagttaa aacaatcgat gggaaagaaa tccagttaac agctttggaa ttcggtatcc
     1141 tctacttgct tgctagtcat cctaatcgag tatttagcgc ggatgaaatt tttgagcgtg
     1201 tttggaaaca agaaagtatt gtctctgcta aaactgtcat ggttcacgtt agtcatttaa
     1261 gagataagat tgaagaagca actggtggtg aaaaagtcat tcaaaccgtt tggggagtgg
     1321 gctataaaat tgacgcaaga tagtaaacga gcaactgaaa aacgccgtcg gatcaatttg
     1381 acttcaaaag aaatcagcga attgttagcg gaaggaatca tcacgattat ccttttgctt
     1441 ctattaaatg tttctattct ggttgttatc agttcggtga tcaacagttc accttctttg
     1501 acgaatgcga tttgggattc aaagaatatt tttgcagaac gattgaacac tgatttgttc
     1561 tggaacggcc ggaattttat tattcccttt ttctttctat tagatattgg tgttttgtat
     1621 tggcgcttga ttcgaagata tcgccaaatg caattgcggc atatcatcag cgaacttcac
     1681 tacatcgcaa acggaaatta tgatcatcgt atcccttttg aactgagtgg tgacttaagc
     1741 cgagtggtaa caagtatcaa tggattggtg gatagtaccg tagcagcgat tgaagacgaa
     1801 cgtaaaatcg aaaaatcaaa agatgaattg atcacgaatg tcagtcatga tatccgtacc
     1861 ccactcacgt ccatcattgg atacctagga ctgatagaag atggccagta tcactcagaa
     1921 gaagatcttt taaagtatac gcatactgct tatatcaaag caaagcagat gaaatcttta
     1981 gtggacgact tatttgaata cactaaggta cgccagcctg ctgtcccggt gaatttttct
     2041 gcctttgaca tgatccagtt gatcgaacag ttagcagctg attttgagtt ggaagcttct
     2101 aaaaaaaata tccaaatact tgttcaatca aaagtagact cccttatcat ggatggcgat
     2161 accgaaaaac ttgtacgtgt cttcaataat cttttgacga atgcgttgaa atacggaaaa
     2221 ggagcaacga agatcgtaat cgaagtagaa cgtatcggtt cagaagttgt tgcaacagtc
     2281 aaaaataacg gagcaatgat cccacaacag gcaatcgata atctattcga ccgtttttat
     2341 cgtgtagaag aatctcgttc acaagcaact ggaggaactg gacttggttt agcaatcgct
     2401 caaagcattg tggctttgca cggcggatac atttatgcaa aatcagataa gcaatggact
     2461 tctttcatca tgcaccttcc aatcaagaaa aatgaaaaat tacctattga tacacaggaa
     2521 gttattgacg aaagctgaaa tattcgctat tcttattaca attattagaa taaatgaaaa
     2581 acacagaacc cagtacactt tattcttttt cagagagctg atggcaggtg taaatcagca
     2641 aaggataatt tggaagttcc agttcgttta cgtgcccttt cgaaataaga aaggtcggtt
     2701 caacagccgt tatgtgttca acaagtgcag ctgacgctga acttgggtgg taccgcgaat
     2761 ttcagactga ttcgtcccaa gaataatggg atggatcagt ctttttttat tttcaaaaag
     2821 gaggaaatca tatgttagat gtaaaaatga tgcgacaaaa tattgaagaa gtacaagaaa
     2881 aattgatgac tcggggcgta aaaaaagaaa cattagctga attcatggaa ctagatgaaa
     2941 atcgtcgtaa gctactagtc aaaagtgaag aattaaaaaa atatcgaaat gatgtttctg
     3001 ctgagatcgc ccaattgaag cgtgcaaaag aagatgcttc tgctaaaatc gctgaaatga
     3061 aagaagtcgg tggcaacatc aaagcattgg atactgaaat tgctgaagtg gatgaaaaat
     3121 tgaaacaaat tgcaactact ttgccaaacc ttccccatga ttctgtgcca gttggaacag
     3181 atgaagagga caatgtagaa atccgtcgtt ggagcgaacc acgtacattt gcttttgaac
     3241 caaaaccaca ctgggaaatt gcagaaaatc ttgatatttt agattttgaa cgtggcgcaa
     3301 aagtagccgg tagccgtttt gtctattaca aaggattagg tgctcgatta gaacgtgctg
     3361 tctacaactt catgcttgat cagcatattt acgaacacgg ctatactgaa atgatcactc
     3421 cttatatcgt caacagtaaa gcgatgtttg gtacgggaca atttccaaaa ttcaaagaag
     3481 atgttttcca attggagaat actgatctaa cattaatccc aacagctgaa gtaccattaa
     3541 ctaactatta taatgatgaa attttagatg gtgcagattt acctatttat ttcactgcac
     3601 taagccctgc ttttcgttct gaagccggaa gtgctggtcg ggatacacga ggactgattc
     3661 gtcttcacca attcaataaa gtagaaatgg tcaaattttc ggatgtagag cattcttacg
     3721 aagaattgga aaaaatgaca gctgatgcag aagatatctt gaaaaaattg catttgcctt
     3781 atcgtgtgat ggccttatca actggagaca tgggcttttc tgcagctaaa acttatgact
     3841 tagaagtatg gatacctgca caagatactt atcgtgaaat cagttcttgt tctaactgtg
     3901 aagatttcca agcacgccgc gcaatgatcc gttatcgcga taatgatgga aaaatccact
     3961 atactcatac tctgaatggt tcaggacttg cagttggccg tacagtagct gccattttgg
     4021 aaaactacca aaatgaagat ggttctgtca cagttccaga agcgctcgtt ccttatatgg
     4081 ggaatctgaa agttattaaa taaagaggct gtgaaaaagc cgcttagttt cgagtattaa
     4141 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta ataccgagaa
     4201 actggctttt gaacaccatt tatcgagagg ttgtgaaatc agcgaattaa cctgagtatt
     4261 agagaaaaaa atggaaaaat agtccctcat attttaccgt ttgttgaact aataccgagg
     4321 gtcagctgat tgaacaccgt ttagtggaga ggtcgtaagc ctacccccca gctcctagtt
     4381 acaaggacaa attcaaaaaa cagctcttca tattttatga atgttgtact tgtgattcgg
     4441 aggtggcaag ggaacactgt ttattcaaaa agaggctggg acagaagcgt ttaactccaa
     4501 gaaataagaa gaaattcacg aaaattgctt ttcaaatttt tgtgaatttc ttcttatttc
     4561 cgaaggagtt gcttctactt ccgccgttta tacgtgttta gagcgtgaga caaaagtgtt
     4621 ctttactttt gtcccacgct ctttaatgtt tttaagattc aactgaatag tttggtgctt
     4681 cttttgtgat ttgtacatca tgagggtgtg attcttttaa tccactgccg ctcatttgga
     4741 taaattgcgc ttcatcacgt aattgctgta gattggctgc cccaacataa cccattcctg
     4801 aacgcaaacc gccgatcatt tggaaaataa tatctgcaac acttccttta taagcaaccc
     4861 gaccttcgat tccttctggt actaatttat ttgcttcatt gacactacct tggaagtaac
     4921 ggtcttttga acctttttcc atcgcgccta atgagcccat acctcggtat gttttgaatc
     4981 gacgtccttg gaagatttcg aattcacctg gtgattcatc tgtccctgcc aacatacttc
     5041 ctagcatcac tgcatgtccg ccggcagcta atgctttgac gatgtcacca gaatatttga
     5101 tccctccgtc tgcaataatc gctttgccat attgacgagc aactgatgct gcatcataaa
     5161 tagctgtgag ctgaggtaca cctacaccgg ctaccacacg tgtcgtacaa atcgatcctg
     5221 gtccgatacc aacttttacg acatctacac ctgcatcata taaagctttt gtcgcttcag
     5281 ccgtcgcaac gtttcctgca atcaatgttg catctgcaaa agttgaacgg atttcttgaa
     5341 tttttcggat cacacctgca ctatgtccat gagctgtatc gatgatgatt gcatctgccc
     5401 ctgcttctaa taaagcattc gcacgctcaa atgtatcgct tgttacacca acggctgctg
     5461 ctacaagcaa tcgaccatgt tcatcttttg ctgcatttgg aaattcgatc actttctcga
     5521 tgtctttgat cgtgatcaat ccgcttaaac gaccttcgtt atctacgatt ggtaattttt
     5581 cgattttatg tttttgcaaa atcttttctg catcttttag agaggtacct actggggcag
     5641 tcactaagtt gtcttttgtc atcacatcag caatcggcat gtgataatct gttacaaaac
     5701 gcatgtcgcg gtttgtaatt atccctacca attttctgtt ttcaagtgtt tcaacgattg
     5761 gcacaccact gatacgatat ttgctcatca attcttctgc gtctgctaca agatgctgtg
     5821 gcgttaagaa gaacggatca atgattacgc cactttcaga acgtttgact tttcttactt
     5881 catccgcttg ctggctgatc gtcatgtttt tatggatcac acctagtccg ccttgtcttg
     5941 ccatagcaat ggccatcttg ctgtcggtaa cagtatccat acttgcactg atgattggaa
     6001 tattcaactt aatattttta gctaattgta cgctcatatc cacttcgttt ggtaacacgt
     6061 gactttctgc tggtatcaat aagacatcat caaaagtaaa tccttttttc gtgaactttg
     6121 tttcccagtt ggacattttt agtaccactc ctctaattta gtttatctat taaaataatt
     6181 gattttttca tttaagtcaa tgatctactt ggaatcaagt tagctttctc atagaatacc
     6241 aatataaagc gtttacatct gtgtgtatta aaagagattg taaaaaagct gtcctgcatc
     6301 aagtaataag aacagccaat caaaaacagc ttctcatgtt tttgaattgg ttgggtttat
     6361 taccgcagat gcaaactttt gaacaccgtt tagtggagag gctgtgaaaa agctgcttag
     6421 tttcgagtag taagaaaaat tttgtgaaaa tggctttcca catttttgca taaattggac
     6481 ttaataccga gaaactggct tttgaacacc gtttatcgta aaaagggact gtgacaagac
     6541 ttttgtcaca gtcccttact attatttaac tatggataaa caaaatgagg ttctttacta
     6601 cccctagata tctagcaaaa tagctgatct ttttgctagt ttatcttctt gggacggata
     6661 aacttccaat aatcccgtat tttttcttca agtagtaacg gattgctaaa gcagttgccc
     6721 cgataatgat aactactact ggatctaata ctggattgat aactggtggc aatagtgttg
     6781 tcgcagaaaa cagtacgacc caaagaagtg tcgttccacc taggataagc aatgtcttac
     6841 ccattcctgg tttcttgctt cgatctgctc cgggatattc atattgatag atgtatttgt
     6901 acatcatata aaagacccag ccaccgattg cagaacctag aacgagtgta gaaaagccat
     6961 aagctggcgt tgttccacgt gaaaacaatc cggtaatcgc aatcatgata cttaatagac
     7021 caagcaacag caacgtatta tctaaccaca tcaataaagg ggtggatgaa ttttttactt
     7081 ctgctggctt attgatgatt gcttccgttc tttcagagac tgtcccaaac aattgacggg
     7141 ctgttcttcc gcctttttgt tctgcaacta aagtaggcag aatgtcatga agggctttta
     7201 ctttttcttc ttcagacaaa ttcgctgctt ctaaagattt tttcaaatca aaaatgtact
     7261 gttgatttct tttggttaat tttgtttcta aactattgtt ttcttttacg attgctcgta
     7321 attgttctgg ttccattatc taatagtcct ccttagccgt tccttttctc aacggtcgtc
     7381 acaaaagaca ttctaccata ttctacagct agtttgatag cccttttaca cattaaagcg
     7441 gaataacatt acgtcgccgt cttgtacgac ataatctttt ccttctaatc gaacacgtcc
     7501 agcttctttt gctgcatgca tgtttccgta atgatccaag tcttcaaaag agacagtttc
     7561 tgcacggata aatccgcgtt cgaaatctga atggatgatt cctgctgctt gtggtgcttt
     7621 gattcctttt ttgaatgtcc aagcacgtac ttcttgttcc ccagcagtaa agtaagtagc
     7681 taagcctaac aaatcataag cagcacggat caactgatcc aaacctgatt cttcgattcc
     7741 taaagcttct aaaaattccg ctttgtcttc ttcatctaat tctgcgattt cttcttctgc
     7801 acgagcactg accacgatca cttctgcatt ttcttctgca gcaaagttgc gcacttcttg
     7861 tacataatga ttcgcgtctg catctgctac gtcatcttct gagacattgg ctacataaag
     7921 aattggtttt gtcgtcaata aaaatagtga tttaacgatt ttttgttctt cttcagtaaa
     7981 ttcgatcgtt cgggcagatt ttccttcttc cagtacaggt ttgattttat ccagtacagc
     8041 tagttctgcc actgcatctt tatctttggt tttagcaact tttgctacac gagtatagcg
     8101 tttgttgata gattctaagt ctgctaacac tagttccaag ttgatcgtat caatatcttc
     8161 tagtggatca acacgtcctt ctacgtgagt aatattatca tcatcaaaac agcgaacaac
     8221 gtgacaaata gcgtctactt ggcggatatg gcttaagaat tgatttccca aaccttctcc
     8281 tttacttgcg ccttttacga ttccagcaat atctgtaaat tcaaaagtcg tcggaacagt
     8341 ttttttcgga tgtacaagtt ctgttaagcg ttgcaaacgc cagtcaggta cttctaccat
     8401 ccctacgttg gggtcgatcg tcgcaaaggg atagtttgct gcttctgctc ctgcttttgt
     8461 gatcgcatta aacaaagttg attttcctac gttgggcaac ccaacaattc cagcagtcaa
     8521 tgccataaat ttattcactc tttctctgca tttttttcaa ttactttttt taatttcttt
     8581 tcaaaatctc gacgggtcat catgacgata tgtccgcaat tcatacatct gattttgata
     8641 tctgcgccca ttcgaatgac ttcccagcga ttcgtctggc aagcgtgagg ttttttcatt
     8701 tcaacgatat cgtgcaagtc gtacataaaa atagcctcct ttttgtttat tcttcatcaa
     8761 attgaatatt caagatatca agaattcgag tcaaatcttt ttgagaaaga tattcaatct
     8821 cgatcttacc tttcccattt ttttcttgga tagctacact tgtaccaaat ttatccatca
     8881 aacgatcttc gctttctcgg atataatatg gtttttcctt tgctagcctt gggatttttt
     8941 tcttttcttt tccatcattt tgatttaact cagaaacaag ctgttccagt tggcggacag
     9001 ttaaattttc agttactgca cgattggcta atttcaagat caatgtttta ttttttaaac
     9061 ctaacagcgt acgggcttgt cccatagata aacgctgatc ttgtaccatt tccttgacaa
     9121 gatccggtaa agaaagcaag cgcaaataat tggcgatata aggtctgctc tttcctaaac
     9181 gactagctac ttctgcttgt gttagtttca ggtttttcat cagcatctca tatgcttctg
     9241 cttcttctaa cggattcaga tcttctcgct gcaagttttc cagcactgct acttgcatca
     9301 tcgcttcttc gtcaaagtct ctaacgatag cagggatcgt ttctttttca gctagtttgg
     9361 acgctcgaaa acgtcgctcc cctgcaataa tctcatatcc ttttactgcg gaacggcgta
     9421 cgatgatggg ttgaaagaca cctgattgtt caatagaatt agctagttcc tgcaaagata
     9481 cttcttcaaa tgttttacgg ggctgatacg gatttggtcg cagctcattc aatggtagct
     9541 ggacaacggt atcatctttt acatccaccg tctctaagtt ttctaaatct tgaaacagtg
     9601 catcgattcc tcggcctaat cctttacttt tcttcacgac ttaccacttc ctttgccaat
     9661 gcttggtaga cttcagctcc tcgagaacgt ggatcgtagt cgatgatcgg ttttccatga
     9721 ctaggtgctt ctgataaacg aatatttctt ggaatgatcg tttcgtaaac tttttcgcgg
     9781 aagtatttac gtacttcttc tacgacttca tttcccagat ttgttcgtgc atcatacatt
     9841 gtcagtaaga ctccctcgat ctctaattct ggattaaagt gtttttggac taaacgaacc
     9901 gtattcagta attggcttaa tccttccaat gcgtaatact cacactgaac aggtatcaaa
     9961 atcgaatcac ttgctgtaaa tgaattgatt gtcagatggc caagagaagg cgggcaatcg
    10021 atcaaaatat aatcatactg actgcttact tctgctaaag atccttttaa tcttgattct
    10081 cttgccatca ttgacgtcaa ttcgatctct gctcctgcta attggagagt cgcaggcaca
    10141 atactcaaat tttcgtgttc agtgatcaaa gttgcctcat caattggcaa ttcattgact
    10201 agaacatcat agatgtctct tgtcacatca ggttttctga tcccgacacc actggtagca
    10261 tttccttgtg catccatatc cactagcaat acttttttgc caaggctagc aagacaagca
    10321 cctagattca ccgtcgtcgt tgttttgccg acgccacctt tttggttcgc aacagatatt
    10381 atttgtgcca tctcttctcc tcctatttga ttggctgctt attaggcagt ccgggctttc
    10441 ttgggtattt ctttggggtt ggtttctttt tttgaataac gatgatatgc cgttgatcag
    10501 agacattcgg caaggtaacc gcctcttctt tgaggaattt accacctaat aaagcaatcg
    10561 cttgttttgc ttctgtcaat tcctcttcac tttttgctgc tttcaatgca taaaaatagc
    10621 cttcttgttt agccaagggc aaacacaatt ccgctaacac attcaaacga gcaaccgcac
    10681 gagcagtgac aaggtcaaat gatgcacgaa agtgaggatt ttgcccaaat gtttctgccc
    10741 ggtcatgata taaggaagca tcgattccta ataatcgggt taactcagat aagaaggtta
    10801 ttcgtttatt cagagaatca acgatcgtta tctgcagttc tggaaaggca atttttaaag
    10861 gtatgctagg aaaccctgcc cccgaaccaa catcgcataa agataaaggt tgcgtaaagt
    10921 ctacttcaaa tgctaatgta agtgaatcgt aaaaatgctt cagatatacg tctttttcat
    10981 ccgtaatagc tgtaaggttc atcttttcgt tccattcgac taatgtccga taataaatag
    11041 cgaattgatt catttgatga tcggtaagct ctatcccttt ttctgccaag gattggcgaa
    11101 attcttctgg tatcataaat attcctttca ttgtgaaaca gcaattgttt cacagattct
    11161 ctccctactt taacgcaaaa tctctagaca tgcaatcctt ccatatggat tcttaaaaat
    11221 ttgaaaagta agaaaagccg atagactttt tctttctagt atgactcata aaatatacac
    11281 agaagagaga actagctttg agcaatttct gcaaaaacta gttctctctt ctatttatta
    11341 ttacgtatta cgctggttca ctgactttcg caatcttccc ttgttcgata tagaccatta
    11401 ggatacttag gtctgcaggg tttacgccac tgattcggct agcttgggca attgtttctg
    11461 gttggatttt ctgcaatttt tgttttgctt ctgttgctaa tccgttgatt gctgcgtagt
    11521 cgatgttttc tggaatcttt ttcgcttcca tgcgttttaa tttttctact ttttccatgg
    11581 cttttttgat gtagccttca tatttgattt ggatttctac ttgttcgatt tcttttcgtg
    11641 tcaattcttc attttctgga ataaaccgta gaagttctgc ataagtaatc tcaggacgtc
    11701 ttaaaaagtc gcttgctagt acaccatctt ttaatggtgc cgcattaatc gttgctaaaa
    11761 agtcttggac ttcttctgtt ggtttgattc gtacattcat caaacgtttg atttcttgtt
    11821 caactgcttc ttttttcttc aaataattct tgtattgatc ttcttttact aagcctacac
    11881 ggtgacccat ttctgttaat cgcaaatctg cattatcatg acgtaaaagc agacggtatt
    11941 cagcacgtga agtcagcaaa cgataaggtt cgttcgttcc ttttgttacc aaatcatcga
    12001 tcatgacacc gatgtaaccg tcacttcgtt tgatcactaa aggttctttt ccctgaactt
    12061 tcaaagctgc attgataccg gcaatcagcc cttgtccagc cgcttcttca taaccgcttg
    12121 taccatttgt ttgtccagct gtataaagat tttcaacgac tttagtttct aatgtcggac
    12181 ggagctggtg tggctctact acgtcatatt cgatagcata tcctgtacgc atcatttcta
    12241 ctttttctaa tccagcaata gaatgaagca tgttgacttg aacatcctct ggtaaagaag
    12301 tagataaacc ttgaacatag acttcttccg tatttaagcc ttctggttcc aaaaataatt
    12361 gatgacgtgg tttgtctgca aaacgcacga tcttatcttc gatggatgga caatagcgag
    12421 cgcctacccc ttcaacgatc cctgtaaaca ttggggcacg atgtaagttg tctcgaataa
    12481 tttggtgagt cgtctcacct gtataggtca gccagcaaga ttcctgatct agtttatagg
    12541 cactatctgg tgtgctgaag ctaaaatgat tcggctcttt gtcaccaggc tgctcttctg
    12601 taacagaata gtcgatcgta cttgatttta ctcgaggcgg tgttcctgtt ttgaaccgtt
    12661 cgatagcaaa gccaagttct tttagatgat tcgctagtcc aatagaaggt tgagagttat
    12721 tcggacctga tgaatatttc aattcaccga taatgatttc tccgcgaagt gctgttccgg
    12781 ctgtaataac aactgctttg gcccggtagc tcgctcctgt ggacgtcact actccatgac
    12841 aaacaccatc ttcgacgatc agttcttcga cgattccttg tcttagcgtc aaatttggtt
    12901 ctttttcgat cgtatgtttc atttctgttg aataagcatg tttgtctgct tgtgctcgca
    12961 atgctcggac agctgggcct tttcctgtgt tcaacatacg catttggata taggttttat
    13021 cgatattctt acccatttct ccgcctaacg catcgatttc tcgaacgaca acgcctttag
    13081 ctggtccgcc tacagaagga ttacatggca tgaatgctac catgtccaaa tttattgtca
    13141 gtaataatgt ttttgatccc atacgtgcag cagcaagtgc agcttctgaa ccggcgtgtc
    13201 ctgcgccaac aacgatcacg tcatacgcat ctgcttcata atgttccaat cgtttgttcc
    13261 tccttttatt ttcctaaaca aaattgactg aataattgag tgattagctc atcttgtaca
    13321 ctgtcgccga caacttctcc tagatagtcc cagcaacgcg tcatatctat ttgaacgaga
    13381 tccacaggca ttcctgaatc aatacctgca atgacttctt caagtgagag ggaagctttt
    13441 tctaacaacg cgatatggcg ggtattagaa acataagtag cgtctctttc tcctgtttct
    13501 ccgctgaaga ataaatcaga aatagctgat tccaaacgat ctagtccgtc gtttttagct
    13561 acggaaattg aaaaaactgg ttcattttcg atcaatttct tcaatttttc ttgttccagc
    13621 tgtgctggca aatctgtttt atttagaaga atgatccgtt tcaatccact tgtcgcttcc
    13681 aataattgtt catcttctgc tgtcagtggt tcgctttggt ttagaacaag taagatcaag
    13741 tctgcttctg ctaatgcttt tcggcttctt tcgaccccga tccgttccac cacatcttct
    13801 gtttcccgaa ttccagctgt atcgattagc ttgagcggta ccccccgaac attgacatac
    13861 tcttcgatta catctcgagt cgttcctgca atatccgtaa cgattgcttt ttcttctctt
    13921 aacaaatggt ttaacaaact tgatttgccg acatttggcc ggccgatgat tgccgtactt
    13981 aacccttccc gcagaacctt cccttgcttg gatgtagcaa gtagcgcttg gattctttgt
    14041 tggatcatct gcgctttttc aagcaataac ttcgtagtca attcttcgac atcatcatat
    14101 tctggataat caatatttac ttctacttgt gctaatgtct ctaaaatctc ttgtctcaat
    14161 gagcggatca aagcagacag attgccgtct aactgattaa gagctagtcc cattgctttg
    14221 tctgtttttg cccgaatcaa atccatcaca gcttctgcct gtgaaaggtc aacacgacca
    14281 ttcaagaatg ctcgttttgt gaattcgcct ggctcagcta atcttgcacc ttctcttaac
    14341 aatagctgca aaatttgatt gactacaacg atcccaccgt gacaattgat ttctactaca
    14401 tcttcccgcg taaatgtctt tggtgctctc atcacggaga ccatgacttc atcgacaagc
    14461 tgattgctct tgggatcaac gatatgtcca taatggatcg tatgacttgg tacttctgat
    14521 aatcgtttgt ttccagattg ataaacttta tctgctagtt gcacagcttg atcgccactt
    14581 aaacgaacga tactgattgc accttctcca ggtggggtag aaattgccgc aatcgtatca
    14641 aattctaaag taatttcagc cattttttca cttccttttt cattttgcgc acaaaaaaag
    14701 tgcccactcc accctttatg cacaataaac ggtgaacttc gcactttgac tgcttgttct
    14761 tgattaaatt ctggtcatag attatcacac ttgctataag gaatcaagtg tttaaaacaa
    14821 ttagatgaag ttgagcctgt tctgcttcca ttaccttata tttaattgtc cttggatgtc
    14881 tctttgcgtt ctttggttta ttcgaagaga agatactgta taaacaaggc tttatctttc
    14941 ttaaaaaaaa cggtacacta aatggtagcg ctatctaaac tatacacttt tgaaaggaga
    15001 aaatatgtga gcccgttcag atctgctgca ttggaagaag aaagtgaccc tcggatcaac
    15061 gatgtcgttt tatctacagg gaatatcaac cagaaatata tcgtccgcga tatcgttttt
    15121 gttgtggaat gcttagaagc tgatttgttt gacccatctt ttcccaaaga tgaccttttc
    15181 ttaacaacga agaggaaatt aaagacgaag gtacttgaat atggtgcgaa tgcagtaatc
    15241 aactgtcatt ttgagtatca gcaaaaaaaa cgcgacggaa agtattttct ggaacttttt
    15301 gcttatggaa cagtgatcca atttatccaa acaacgattg gttaaatgaa acagacaaaa
    15361 aaagcggatc aaaactgaag acagtttcga tccgcttttt tctatcaaag ttagtgacta
    15421 cttcatcgta tactctgata agaatgattt ctagtaaaat atacttggtt tgaaaaactt
    15481 tgtcaacgtg atttattcaa aaagtaatgg aatcaataat attttttagc aggttctact
    15541 actaaataac gataaggttc ctcaccttcc gaatgtgttt ttacatgttc atctttgctt
    15601 aatgcagcat ggatttgttt acgttcaaat gcaggcattg gttctaagaa aacaggctgc
    15661 cctgtccgtt ttactttttc agccgtgcga tcagctaaac gctgaatgat ctcttggcgc
    15721 ttttcacggt aattgcctac attgactact acagacagct tatttcttgc taaacgatgg
    15781 atgaagactt gtgccagata ttgcaatgca ttcagtgttt ttccatgttt cccaatcagt
    15841 atgccttgct tttgtgtttc taaatggaaa acaaccatat tatttgattc tctttccatt
    15901 ttgacaagag ctggagcatc aagctgtttt gaaatttcag taagataaac tgccaattcc
    15961 gttaaagctg cttcatcacc tagctcactt acttcttctg ttttttcttc aagaatcgtt
    16021 tcgttgacta cctcgatctc agctgttggt tcttcttcca aaatttcttc tacagtctgt
    16081 tctactgttt cagaaacttt ttcgctgata cttggctgga tcgaaagccg tgcattcttt
    16141 cgacccattc ctaggaaacc tttttttcct tcttccagta tttcgatttc gacttggtct
    16201 ttggccaaac ccaaatcagc cagacctagt tggacagctt cgtctattgt tgcagcttca
    16261 taaatcggca ttagcattac ctcccctatt atttccgttt tttcttagga ttcattgctt
    16321 tcttaagagc acgttctctt tcgcggattc tccgtgcttc ttcttcacgc tcttttcgaa
    16381 ttttgaaagg gttgttgatc agcagcgttt gtacaacttg gaaggcattg gaaactaccc
    16441 agtataatga aagaccgctg gctaaattga cacccatcac taaaatcatt acaggcatca
    16501 cgaaattcat gatcttcatt gatgcattcg attcaatttg actcatgcta gataaatacg
    16561 tacttgcaaa agtaaagatt gctgctaaaa tcggcaaaat aaatgttgga tccgcgttcc
    16621 ctaagttcaa ccataagaaa tgcccttgtt tcaactctgg tacacgtgaa atagattgcc
    16681 ataacgccat caagattggc atttgtacta ataaaggaag acaaccagca tatggattga
    16741 cgccattttc tgcatataaa cgctgctgct cttctcttaa cttactttgt gtttccggat
    16801 ctcttgaact atattgttgc tgcagtgctt ttaatttcgg ttgtaattct tgcgttttac
    16861 gcatgctctt tgtttggaaa tgcatcaacg gcaataggat cacgcggatg atcagtgtaa
    16921 ataaaatgat ccctatccct gcattaccaa atgacaacgc cttgatcgcc tcagcaaagt
    16981 aataaacaat ataacgatcc caaattcctg tactctgtgc gctgacttcc ccagttccgc
    17041 aaccggataa gacgatgacc aaactaacga taccggccat caaaagtaaa cgtttgtatt
    17101 tcttcactta ctcttttcct ctctgtcgat tatttttgca agttttaaga cgtggactaa
    17161 attggagcga acctcatcat aagtcaaccc cttcacactt ggtctagcaa tcacaataaa
    17221 atccaactcc ggatcaattt cttcttttat agaataaact gctgctcgga tttttcgttt
    17281 gacttcattg cggtttaccg cgttgccgac cttttttcct acagataaac caactcgaaa
    17341 atgaggctgt cccggttttt ccaaacggta aacgacgaat ttgcggttag caaaagaatc
    17401 tcccgtatgg aacacggctt gaaactctcg ttcttttttt actcgatacg cttttctcat
    17461 tagttttctt tccttttcta tctctcactt acgctcataa tcataccata attacgattg
    17521 tcctttcatc atttccctaa aaaagagtat aaaaaaaacc actgaaaccc cagtggccta
    17581 agctgaaaga acttttcttc ctttgcgacg acggctagct aacacacgac gtccattttt
    17641 agtactcata cgtttacgga atccgtgaac tttttgacgt ttacgtttat ttggttggta
    17701 tgttcttttc atatattcca cctccaaaat gttcttatct attttataaa cacagacata
    17761 ctttgatagt ataacgacaa agtagtgatt ttgtcaatat aaaatagaag atcgattgtt
    17821 aaaacttatc cacaagatta tttttttcta tgggaatcct atgtggaaaa agttatgcac
    17881 agggattatc cacagataat aaaaggctgg ttttacacag aaaacacacg tgtaaaaaaa
    17941 gtaatccaca atcaggcgat ttcctgtgta ttccgtctcc taactattgg tatatctgta
    18001 ttttttatcc acagacgcaa gaggaaatct attggttttt acgagttttc cacctgtgca
    18061 ttagtggtgt ggaaaacttt ttttgacaac tgtgtttttc tcttttttct ttttgtcgat
    18121 tgtgtggata attgtaatta aaaaattttt ttcttcggtt tctgtggaaa actattgaaa
    18181 aaaatgctaa attagtacta gttattcact ttttaatgaa ggaggaggcc ttatatggta
    18241 tccctcgatg ctttatggaa tgaattaaaa gcaacatacc aaaaggattt atcgcctgct
    18301 agctataata catggatcga aacagcgaac cctcgaaccc ttgatcaaaa ccagctcgtt
    18361 gttgaggttc ctagcaagat tcataaagaa tattgggaaa aaaacctggc gacaaaaatc
    18421 gttgaagtcg gttatatgtt atcaggaaat gagattatcc ctcgctttat tactggcgaa
    18481 gaagcagagc aagaagaagt tatagaagaa aaaaatccaa aagttgtggc acctagtccg
    18541 ctaaaaaaag ccatgctgaa ccctaaatat acctttgata cgtttgtcat tggtaaagga
    18601 aaccagatgg ctcatgcagc agcgctcgtt gtagcagaag atccaggttc tatttataac
    18661 ccgctcttct tttatggagg cgtgggactt ggtaagactc acttgatgca tgcaattggt
    18721 catcaaatgc tgcaaagtca gcctaatgcc aaagtaaaat atgtaagcag tgaaactttt
    18781 gctaatgatt tcatcaattc gatccaaaac aaaacagcag aagagttccg tcaagaatat
    18841 cgaaatgttg atttactgct agtggatgac attcaatttt ttgcagaaaa agaagctacg
    18901 caagaagagt ttttccatac tttcaatgcc ttgtacaatg aagggaaaca aatcgtacta
    18961 accagtgatc ggttgccaaa cgagattccg aaactgcaag aacgccttgt ttctcgcttt
    19021 gcatgggggc tgtctgttga tattacaccg ccggatcttg aaacaagaac agcgatttta
    19081 cgtaaaaaag cggcggctga acgtctagag atcccagatg acacactaag ctacatcgca
    19141 ggacaaattg attctaacat tcgtgaatta gaaggtgcgc ttgttcgagt gcaagctttt
    19201 gctgcgatga atagtgaaga tatttcgact agtctagctg cagacgcact gaaaacgtta
    19261 aaatcaggaa aaggacatcc tcaattgtca atcctgcaga tccaagaaga agtggcaaag
    19321 tattatcaca tccaattgaa agatctcaaa ggaaagaaac gcgtcaaatc tattgttgtt
    19381 cctagacaaa tcgctatgta tttggcacgt gagctcacag ataattcttt accgaaaatc
    19441 ggagctgaat tcggtggcaa ggatcataca acggttatcc atgctcatga aaaaatccag
    19501 cagctgatgg attctagtgt cagtatgcaa aatgaagtat cagaaatcaa aaacttttta
    19561 ctaaattaat ttgtcgattc tatcaactga aaatagcatg tggataaaag aaaaaaacgt
    19621 tcaaaagtta tacacacttt ttccacagct gttttttcgt ttctctctta cgttttttga
    19681 gttttccaca gaatcaacat gccctattac ttttattatt ctttttaact aataataaat
    19741 aaacaaacat tcaaaggaga tacatcatga aagttacttt aaaccgagct agctttatgc
    19801 aggaattgca aactgttcaa cgagctattt caagcaaaac cacgatccct attttgacag
    19861 gtgtaaaaat cacactgaca caagaaggtt tgactttgac ggggagcaac gctgatatat
    19921 caattgaaac ttttttgtct gttgaaaacg aaaaagcaaa tatgcaaatc gaatctactg
    19981 gttccattgt tttacaagca cgtttcttta gcgaaatcat tcggagactt cctgaagaaa
    20041 catttacttt agaagtttta gaaaataaac aagtagcgat cacttctgga aaagcgaatt
    20101 ttatcgtaaa tggattagat gcagataact atcctcatct tcctgttgtc gaaagccata
    20161 accagatgaa attacctgta cacgtattga ctaaactaat caacgaaaca gtttttgctg
    20221 tctcacaaca tgagagtcgt ccaatcttga caggtgtgca tttcatttta tctgataatt
    20281 ctttattagc tgtagctact gattctcacc gtctaagtca acgcgtgatt ccagtagaac
    20341 aagcggctga tcattttgat attgttattc ctggaaaaag tttgatcgaa ttatctcgct
    20401 cattaacaaa tgaagaagaa atcgtcgaaa tcagcattat ggaaaaccaa gtgttgttca
    20461 aaacagaaac gatgtatttc tattcccgtt tgctagaagg aaactatcca gataccaatc
    20521 gtttgattcc ttcaagtttt aatacagagg ttgaattttc tgttcctagc tttttagcgg
    20581 cgatcgaacg ggcttcttta ctttctcatg aaggccgtaa caacatcgtt cgtttatcta
    20641 ttcgtccaga tgcggttgtt ttatacggaa attcgccaga aatcgggaaa gtagaagaaa
    20701 gcttgagtta tacagcaagc agtggcgatc cattagatat ttctttcaat ccggattata
    20761 tgaaagcagc gttgcgtgca tttggagata tgagcatcaa agtgaaattt atctctgcta
    20821 ttcgtccatt tacattggaa ccaacggaag atggcgttca atttattcag ctgattactc
    20881 ctgtacgtac aaattaacaa tgattttcaa tgttcttgaa aatttaattg aaaagaaata
    20941 gaaaaaataa aattttaaac agaaggccct aaaatctctt ttaaggctt
//
LOCUS       DAZAOD010000047        20778 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000047 DAZAOD010000000
VERSION     DAZAOD010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.048"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(128..1015)
                     /locus_tag="ACHDPO_001663"
     CDS             complement(128..1015)
                     /locus_tag="ACHDPO_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFN3369284.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            1200..2039
                     /locus_tag="ACHDPO_001664"
     CDS             1200..2039
                     /locus_tag="ACHDPO_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFN3369285.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            2235..3209
                     /gene="sgrA"
                     /locus_tag="ACHDPO_001665"
     CDS             2235..3209
                     /gene="sgrA"
                     /locus_tag="ACHDPO_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFN3369286.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            3507..3863
                     /locus_tag="ACHDPO_001666"
     CDS             3507..3863
                     /locus_tag="ACHDPO_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369287.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            3995..5023
                     /locus_tag="ACHDPO_001667"
     CDS             3995..5023
                     /locus_tag="ACHDPO_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369288.1"
                     /translation="MYWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWIS
                     LLRISLQRMKQGHSITYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTE
                     QAYLYFMFGVMNTYLEEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLY
                     VNLAMIHLYSRVFGTKKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNT
                     YYEKNRRLIFQYCMLVRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYS
                     ASADQLPDIVISDYPIDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSI
                     LEKLDFVN"
     gene            complement(5049..5489)
                     /locus_tag="ACHDPO_001668"
     CDS             complement(5049..5489)
                     /locus_tag="ACHDPO_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFN3369289.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            5649..6155
                     /locus_tag="ACHDPO_001669"
     CDS             5649..6155
                     /locus_tag="ACHDPO_001669"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFN3369290.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            6323..8236
                     /locus_tag="ACHDPO_001670"
     CDS             6323..8236
                     /locus_tag="ACHDPO_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFN3369291.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            8241..9242
                     /locus_tag="ACHDPO_001671"
     CDS             8241..9242
                     /locus_tag="ACHDPO_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFN3369292.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(9444..9650)
                     /locus_tag="ACHDPO_001672"
     CDS             complement(9444..9650)
                     /locus_tag="ACHDPO_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFN3369293.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(10296..11144)
                     /locus_tag="ACHDPO_001673"
     CDS             complement(10296..11144)
                     /locus_tag="ACHDPO_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFN3369294.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            11308..12210
                     /gene="gnd"
                     /locus_tag="ACHDPO_001674"
     CDS             11308..12210
                     /gene="gnd"
                     /locus_tag="ACHDPO_001674"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFN3369295.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            12212..13213
                     /locus_tag="ACHDPO_001675"
     CDS             12212..13213
                     /locus_tag="ACHDPO_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFN3369296.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            13210..13494
                     /locus_tag="ACHDPO_001676"
     CDS             13210..13494
                     /locus_tag="ACHDPO_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFN3369297.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            13527..14324
                     /locus_tag="ACHDPO_001677"
     CDS             13527..14324
                     /locus_tag="ACHDPO_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFN3369298.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            14338..15171
                     /locus_tag="ACHDPO_001678"
     CDS             14338..15171
                     /locus_tag="ACHDPO_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFN3369299.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            15189..16046
                     /locus_tag="ACHDPO_001679"
     CDS             15189..16046
                     /locus_tag="ACHDPO_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFN3369300.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            16068..16577
                     /locus_tag="ACHDPO_001680"
     CDS             16068..16577
                     /locus_tag="ACHDPO_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFN3369301.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            16614..17015
                     /locus_tag="ACHDPO_001681"
     CDS             16614..17015
                     /locus_tag="ACHDPO_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369302.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            17127..17480
                     /locus_tag="ACHDPO_001682"
     CDS             17127..17480
                     /locus_tag="ACHDPO_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369303.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            17514..17957
                     /locus_tag="ACHDPO_001683"
     CDS             17514..17957
                     /locus_tag="ACHDPO_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3369304.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            17974..19059
                     /gene="uxuA"
                     /locus_tag="ACHDPO_001684"
     CDS             17974..19059
                     /gene="uxuA"
                     /locus_tag="ACHDPO_001684"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFN3369305.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            19052..19765
                     /locus_tag="ACHDPO_001685"
     CDS             19052..19765
                     /locus_tag="ACHDPO_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFN3369306.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(19972..20121)
                     /locus_tag="ACHDPO_001686"
     CDS             complement(19972..20121)
                     /locus_tag="ACHDPO_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369307.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            20517..20717
                     /locus_tag="ACHDPO_001687"
     CDS             20517..20717
                     /locus_tag="ACHDPO_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFN3369308.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7104 a         3207 c         4317 g         6150 t
ORIGIN      
        1 tgttttggta caaataaaaa aaggccccga tgaagttgtg gcaaaagtgg tttgcctcaa
       61 aaataagaag gaatttccaa aaatcacttc tcaaattttg ccacatcccc aattgggtca
      121 aatttgttta tttgaatata ttttttacat aaggatcttt aatagttaca ttgtcttttt
      181 tcatcacttt acggattgtt ttatccatga attccgtatc aagagttttt gcttcggtag
      241 caattttttc tagctcagat ttgtatttgt ctttattaga acctttatcc tgttttttta
      301 ccatttttac tagataatag ctttgctgat aagtcgttgg atctgttaca ggaatgatat
      361 cagaaacttc cccgtttttt agtttaaatg ctgctttttt tacttcagta ggaatctctg
      421 gattggttga atcaaaattc atttttccat cagtttcctt taatgtttta ttttttccat
      481 aagcttgaac aagcttggag aaattttctc cttcatttgc ttcttttttt gctttatctg
      541 cttcttcttt agtcgaaaat agaatgatct gtgtactaac ttctggatag aattctttcc
      601 aagcagtgtc tagatcttta tctgttaatt ttacattggc tttcaaaccg tattggaaag
      661 ccagcatctg tttaaagagt ttcttatatg tctcttctgt ttggccaact gcttttaatt
      721 gttccttgta gtttggaccg agttttttga tttgttcatt atattctttt gttacttcct
      781 ttgaagaaat ctcttttccg tatacatcat caaatgcttt gaagacaatc atttttttta
      841 atagtgtttg attatttgat ttaacttttg ggttatcata aaaatcctga actgtaagtg
      901 ttccaccttt aaacgttgca atcgtttcat tggacttgct acaacctgag aatagtaaaa
      961 ttgcacatgc tgaaaggcac ataattagta gttgtttttt caaaaaattt cccatccttt
     1021 ccttattaaa aacagtctaa cagaagaatt agggagacag tctttcattt tcgtaaggtt
     1081 gctgtagata ttcttagttc gtaaaaatct attctctcta tgatggagaa catttacata
     1141 gttttcacga gacaagaaag aaaagggttg ttaaacttaa tataaaggag ggatgaaaga
     1201 tgatcaggat tattcggttg attggatctg ttttaatagt ctttgttggt tttgttttag
     1261 gaattcttgt caataatgca cttgcggata tgtttattgg aaatagtgaa tggattggag
     1321 caattgccgg tacggtcgga catttagctg tttttttact agctttattt cttgctagta
     1381 aggtcgaagg aaaaagaata gaagattatg gtgtttctgt tcgaggaaaa gactgggggt
     1441 atttagcggg aggtctcgtt gttggaattg gagtgtttct gcttattact agtccattat
     1501 atttgacggg ggcgtatcgg ttagattcag gaaacgcaaa cattgtgccg ctgataacga
     1561 gttttatttt atttattgca gtgggggcat cagaagagct tttattccgt ggcttttttc
     1621 agcatcagat gcttagattt ggtccgttaa tagcaatgat tggatctgct gcattatttg
     1681 ctcttttgca cggattgaat cctaacatga catttctggc agttttcaat atctttttag
     1741 caggttgctt tttcagcgca cttatctaca gtacaggaag tttatttacg gctattggtg
     1801 ctcatattac ttggaattgg acacaaggag ctattttggg tataccagtc agcggaacgc
     1861 aagaacaagg ttttttctcc actctgatcc aatcgcaaaa tacaataatt actgggggaa
     1921 actttggggc tgaagcatct atatcaacta cattattctt gttagtcttg attgttggtt
     1981 tgttactcta tgcatataaa acaaagcgga tgaagaaata cactgctgtt tatcaataaa
     2041 agatgaagaa agcaaggctg atatcggtct tgctttttta agtctgtcat tgattaaacg
     2101 aaaaagtaaa caaattcaag cgaatacacg acatcttttg ttagattttc acaactgact
     2161 gtcgtgttct catcattttc attttatata attcctttat caaatagaag gtaattatat
     2221 ggagagtgat agaaatgaag aaaacagcga ccgtattatt tgttattctt gggctgagta
     2281 taattgcagc aatgattgga atcagtactt ctgcaaatga acgggcaaat gagaatcttt
     2341 catttactgt gaaaactgat cggattgttt atgacatgac acaacaagtc attactattc
     2401 cagtcaaacc aaacaaaagc gtgaatgcta gtgatgtaca tgctgttcta acatatggtt
     2461 gggatggtaa tggaagttca gaaaaagtta ttggggaagt ttatttaaaa gacgtacaat
     2521 ggaccgctgg tattgagtat acaataatga tttctgcaga actatcgatt gatgagatca
     2581 agagtaaaga taaagttgat ttgattgttt tttatgatgg acagatgacg atcacggaga
     2641 atttgaaacc aagcagttgg acagttgttg gaccgccaag cagtacggat agcacaagta
     2701 gtgaaagcag tacagaaaac acgagcggtg aaagcagtac agagagtacg agcagtgaaa
     2761 ttagcacaga aaacacgagc agcgaaagca gtacggagag tacgagtagt gaaagtagca
     2821 caggaagcac gagcagcgaa agcagtacgg agagtacgag tagtgaaagt agcacaggaa
     2881 gcatgagtag tgagagtagc acaggaagca cgagcagcga aagcagcaca ggaaaagtaa
     2941 ataatgaact tgatttggta cctatcatac caactaagga acaaaagaga aatgcaggga
     3001 gcaacctaaa aagtgtgcta aaacagcctg attttgtttc tcgtggaatt gatcatcaag
     3061 aaaaagcgaa agaaacagat aatagaaaaa gcgatttacc agaaactggt agtagaacct
     3121 tgaacaagct aattacatgg atgggtgtgt tactcatttt gattgtagga gcaagctatt
     3181 ttcgttctct cttccatcga gtgaaataaa gaataaaagc aacagatcta aaattgaata
     3241 aaacgataga tttttgagtg aatatttcat tcgagagtgc tgtattgcct ggcgaagttg
     3301 tagctttgcc agatctattt ttgtttacta acatatttga gaaacaggaa ataacaggaa
     3361 cacaaatgga aaataagagc aagaataatt gacaatgcac actgcgcatg gtagtatctc
     3421 tgaaaaatca gtaacgaatc tatttgtacg ttattcatgt agctgtcgga ataagtctaa
     3481 ataatagata aaaaggagta tgtactttgt ttgaagaatt tattgatatc aatgaaaggc
     3541 aagtatatca atttttgaac tattgttatg aaagagacga gaaattatat gtggtgaagg
     3601 atatcgcttt agatctaaac tacaccctgg ctaagatgaa ttcggtgatt caacaagcag
     3661 aatcgttttg cgaaaggtat ccagaatata aattatcttt tctttcagaa aacaagatga
     3721 taaaagtcga gttttcttct cagtttttac tgagtaaagt ttattctata cttttagagg
     3781 gaacgattgg ttatatttta ctggattcac tttacaaagg tacttatcaa tccttagaaa
     3841 atcttagtca aaaaattata taagtttgcg tacgattcaa agaaaattaa gagaacttaa
     3901 tactattttg aaaaactatc atttatcttg cagcttgaaa aaaggtaatc cgatagaagg
     3961 agaagaatac cgtatccgat acttttttca cttgatgtat tggcagtcat tcgacgaaaa
     4021 tcattctgat atattatcaa gtataaaaaa taaacgtcaa ctattagaaa aatttgcgaa
     4081 acatgcgcca tatacgcgta gtatagatag aaagaaatgg atcagcctac taagaatttc
     4141 gttgcaacga atgaaacaag gccactcgat tacgtatgtc ccagaagaga tgaacaaatt
     4201 tgtgcatcca ttgataacaa aagaagagtt tacgcattac atactagagc ctttttttga
     4261 agcaaacttc tggtcgatga atcacatcac tccaacagag caagcttacc tttattttat
     4321 gtttggtgta atgaacacct atttggaaga agatttgttg gatactccag ataaagtaca
     4381 agaaagttgg ggctggattg aatcgtctat tgtagaaaat tttgaaaaaa acttcaagat
     4441 ttgttttaca acttcagaaa aaaattatct atatgtcaat ttggcaatga tccatttgta
     4501 ttcaagggtt tttgggacaa aaaagaaggt ggatgctttt ggaaaatcag cagaagacag
     4561 agattttcag catatatttc cagtgatgta tccaatcatg caacagtttt ttagtggggt
     4621 agctcgcaga attccagagc ttaatactta ttatgaaaag aacagacggt tgatttttca
     4681 atactgtatg ttagtcaggg atatttttat aaaacacgaa caacctgtca tattctatat
     4741 tcaatcaaag tatggtaaaa cacaggaatt atgggcaaag aaaaggatat tatctatgac
     4801 tgaacgccca ataaaatata gtgcatccgc tgatcagtta cctgatattg tcattagcga
     4861 ttatcctatc gacaaaaagg catatgatca aacgaataca cagatatttt actggaatgg
     4921 acaacctaca aaaaatgatt gggcgcgtct gaaagctgaa atcataaaaa tcaggaatga
     4981 gaaaaataga tccatattgg aaaaattgga tttcgttaat taagaaaagc agattgttta
     5041 tgccaaaatt aagacattgc aaaaagatta ttttctttaa aatcgacaag atgaccagaa
     5101 agcaagagtt cgttgagctc ttgctttctt ttagttttag aaaggaacat cctgatttta
     5161 tcttcgctaa atccagtcaa aagttttgca gattggtcgt agataatcgg ttttttcaat
     5221 aaagaagggg atgtacgaat ctcaatatat agttcactca aactgagttc atctattctg
     5281 tgaacaagat ttttataact aatagaatga gtagagagca tttcggtcac gccgttgttt
     5341 gtcaatttta gtaagtggat aaattcattt ttggttagtg gttgacgaat taagttctgt
     5401 tcgataaacg gtatatcatg gacgataagc caacgttttg cgcgtcttga agacgagcag
     5461 ccagaacctg tatacaattt aatcatcata cattcctcca atagctaagt atttatgaaa
     5521 taataacatg aagaaatagt cgaaaagtgc catttagagg tgtaaaataa gaaaatgttg
     5581 tcacgtataa tggaactagc tagataagaa atactattaa atcaagaaaa aagaaagaag
     5641 gcacaagtat gtcaaacaca gccgacgcaa tagtagtgat cgatttacaa aaaggggtat
     5701 gttttgattc ttcgccgata cacgaattag aaacagtgac agcattagtg aataaaagaa
     5761 tcaaaacata cgaaacgatt gggaaaccag ttattttcgt tcaacacgaa gatgctcaat
     5821 tagtgccaca aacaaaacca tgggagctat tgtcggaatt atctattcct gagcacagtt
     5881 attttgtgag aaaaacccat gcgaattcat tttataagac taatttgagt gttttattaa
     5941 ctgaattgga ctgtcattcg atcgaattat gtggggcaca agcagagtat tgtatagata
     6001 cgactgtgaa gtttgctcat ggattaggat accagcttat gatgtgtaga ggagcaacga
     6061 caacttatga taatcctttt atgaaagcaa aggaaacaat cgctttttac gagaaaattt
     6121 gggataaacg atttctgaca tttttggagc aataagttgt ttcttcgttt aaaaaaagca
     6181 gaatggatac tggtttatcc attctgcttt attacgtaaa atgagaaaat aatcctgttc
     6241 tatttttatg ggataaacca tttatttttt gtataaaaaa tgtttgcgtt tacatataat
     6301 tctcctagaa acataaaaag gagtgaatag cttgagaaca aaacaagtat taaagggagc
     6361 gttggtcatc ttatttgctg taagtacaag cgtcccgcaa tggacagtat atggagagag
     6421 catttcttcc gaatcggaat ctcgggaggt agaaaccaca gaaactactg atgctggaaa
     6481 tgaaacgaaa tcgagtactt cacaaacaga aacaaatact gaaacaacgg ttgagacatc
     6541 tgttactagc acagatcaag aaacgaccgc taccacagat aaccaacaaa cagaagaagc
     6601 aacagctaca aaaatgtcaa acgacgaatc ctcttctgct aaagtaagtg acaaagagaa
     6661 tgggacagaa aatgatgata tcggtaaagg tgaaaatttc aatggtaaag aatatttgaa
     6721 ttacttcggt aaacagatga cagaaatact taatggacca acagaagaca tcaagtcaaa
     6781 attaatagag ttattagtca ctgagcttgc tgttaatgat tatggtgtag ataaagagat
     6841 tatcaaacat ctgattgcta cttatctatt gtacgatatc gcttttgcaa aaaacagtgt
     6901 gttgatgtcg atgcttggag gtacagatga tgggacaacg cctacagaaa acacaggctt
     6961 ctatccaaat acaaaacaac ttcatcaaac tgtactaaac aaacaagatg gcaaaatgat
     7021 ggatgtatat gcatattatg tcgatcaagg ttcagataaa acagtcatga tccatggcgg
     7081 atttcgaggg aattggaata acgggatcgt tacagaagaa tacaatgatt tttataaggc
     7141 cgggtataat ttattatttg ttgattccag agcgactggt aatagcggag gcgattatgt
     7201 gacctatgga caatatgagt cagatgacgt cctttactgg ataaatcaag aagttcgaga
     7261 gcggccatct caaaagattt tactttatgg tggttcgatg ggagcagcta cgatgatgtc
     7321 tgtattagcg aaagatattc ctgtcaatgt caaaggaatt attgaaaatt gcggatttgc
     7381 atcaattgat gaacaactac gttttacgta cagccagaca gtagcccccg cactaccgga
     7441 tgccataaaa aatcagttag acatcattgg ggatcaagag catgaagatt tatttatggg
     7501 ccttttgaaa caatactatt ttgatcagga gatgcatttg gatacaaaag ctgctctacc
     7561 tacgattgga atgtcagatt cattgcctaa attgattatc catggaacag cagatgatgt
     7621 agtacctgtg tctaacgcgc aaaaattata tgagttatca ggagggtata aagatctttt
     7681 attagtagaa ggagcagggc atggaaaggc acaggaagtt gaccatgctg cctacacgaa
     7741 acatgtaacg gactttttga aagtagtgtt ccatgatcag ataaacgtaa agtatgtgga
     7801 tgaaaacaat aaaagtctac tcaaagacca ggacgaaatc cagctttacg gagcttatgg
     7861 agaaaattat atgacagagc aaaagacatt cgaaggatac gaattagcaa atgttgaagg
     7921 accgactgaa gggattttta atgagacgat accaactatt attttctatt acaaaaaaat
     7981 cccagtagct ccaccaaaaa agcaagatcc gacagagaat gcagacaata agggaaagaa
     8041 tgaacctcga gaggatcaat caagtgatga tacgcaaccg attcagatga cagtgaaagt
     8101 acaaaaaaag acagatgcaa aaaaaagaat gttgccgaaa actggagaaa agaaacattc
     8161 gcttctcatt tattcaggtg gatttttatc tgttagcacg attatcacat ggatttggcg
     8221 aagaaagaga gggtaaatga atgaaatggt tcaagcgaat agtgattgca gtaccagtta
     8281 tcatcgtagt tattttagtc actgtatttt tgattaatca aatcacacca aagccgatta
     8341 gcttgcttgt tagaaaacaa tttgacacaa gtgaaaaaga acaagtatat gcccgaccag
     8401 atgatttcca gcaaaaaatc gaacaaatcg atataaaaaa agaaatatcc tatccttcaa
     8461 agtacaaaaa taataatatg gatatctaca caccgaaagt ggaaaagaaa aaattaccga
     8521 ttcttttctg gatgcatgga ggcgcatatg taggagggga taaaaatgat tgtcgtgatt
     8581 atttggaata tctatgttca gacacgcagc aaatcatcgt aaatatagat tatgaacgat
     8641 caccggaagc aaaacatcct acaccagtta tccaattgaa cgaagccatt caagcagcta
     8701 aaaaagagat aaaagatcaa gcagattggt cgaatatttc gattggtgga aattcggcag
     8761 gtgcacaaat tagtggagaa tatttgttag cacttcaaaa tgaagaaatt aaaaaagctg
     8821 atcatcttga tccgactttg gagaacaagc agattacgaa gtttatttct ttgtctggtc
     8881 tgttggatcc ttctgcactt actcaagtaa gtgataaaat ctctagcttt ctttatgaaa
     8941 aatgtggatg ggcttacttt gataataagg actttgaaca atcagagaag gtcaaaagtt
     9001 tagccttggt cagacatgcg gatcgttgga cgcaaaacac attcttaacg gatggaaata
     9061 caaatacgtt tacgaaacaa atggaagaag taacttctgt atttgagaaa gcgggggtga
     9121 aagtcacaaa agtagattat gcggagaaaa atgctgtttt gaaccatgaa tatcagtttg
     9181 atttcagcaa taaacaagcg caagaaacat atcaaaagtt agtaatgttt ttcaaggagt
     9241 aaagtcttat gatgcaaaag aggttgtaat ctgtcactta gctccaagtc acaaggagca
     9301 atttcaataa acaagctttt catggtttat gaatattgta acttgtgact gaggagttag
     9361 agatggcaag gggcaccttt tattcgaaat ttgggaatat cacacgatta ttgtcacgat
     9421 ctcttttacg taaattttat aagtcagatt tgttgttttg atcgtttaaa aaaagcaaca
     9481 aatccgaagc ctgcggaggc aagaagggac aaaaagccga gtggtaagca aaagaatgct
     9541 ggttccacta atattccgtt gttattgata taaggctggg aacaaagatg aatagcaaat
     9601 aaaatcaatg cactagcgaa aaaaagcaaa gaaatatgga tagctttcat aagcagcacc
     9661 tcctttttta taattgtatg ataaatagat taagaatcta taaatgtgac aagtttgtta
     9721 ggatgtgaat aaaatgatca tctagcgaac ttgaaacaaa gatggctaat gataagcaat
     9781 taatgattca gcaatcagat aggtacaaag tttaccatca tacgtctaga ccaataatag
     9841 aaaatatggg aatataatag aaaagattta ggataccccc aaaagaattt ccccaaaaat
     9901 tcgatgtatc ctaaactttt ttattttaca taacaatcat atcaactgtg aaataaaatt
     9961 acaaatgata acctaaaatg aggccaaaag ccagtgttat caaggaaata cttaattcac
    10021 caaaattttt tttaattttt tagaaaataa gaaacaaaaa taataaaaaa aagaaaagat
    10081 aaatttttta ctactgtata ctaactttgt tatcgcatct aacaagtaac tcgaataata
    10141 ccaatacaac cttctccaaa gatgcgatga catacgttct aacccaccga ctattgatgt
    10201 tctgtaccac ccttgcagaa ccaaaaaagc cactaccaaa tatttggtag tggctttttt
    10261 tgttttatgg atttttcgct ttttctgtta tggtgctatt ctttgatttc agaaatagta
    10321 tgtcgaactt tagcgataga acgacgtgat tctttttcgt tgtaaaacat caaaatcaca
    10381 tatagagagt ccaaaatgct tagttgagaa atacgggaag ctaaagcttc agatcggaat
    10441 tctgtttctt cagaaataga aataaaaacg acatcgccaa gtttagcaag ggaagaatta
    10501 gcttggctag taataacgat tgtttttgct ccagtttttc ttacggtttc agcaatatgg
    10561 attgtttctt ttgattgccc tgtgtgagaa atcaaaacag cacagtcttt ttccgtcaat
    10621 aaagaagctt ccatcaattg aatatggtaa tccgtgctgt gagaagttgc gataggggaa
    10681 cgcaaaaatt tatgataagc gtcagttgct acaatctctg aaccgccaac accgaaaaaa
    10741 tagacacgtt tagattcatt gataatagta gccgcttttt ttagatcctt ttgttgtaac
    10801 aacttttttg tgtcatttaa agttgaaata ctagactcga acaccttttg cgccatagtg
    10861 agctcagtat ctgttttctg aatattttcg tggatagaaa tagcagatag atcattttct
    10921 tggatcaaca tggccatttt aaaatcttta aatccattat aaccaagttt ttttgtaaat
    10981 tgaaaaaaag tagagtcagc aatgcccagt tcacttgcta aattgctaat aggactatga
    11041 cttactttgc ttggattttc taaaatataa tcggcgatag cctgttcttt tgggctgaag
    11101 tcgttgtaca ttgttttgat ttgtagtctt atggagacgc tcatgagaat tcctcatttt
    11161 cataataaga ttatcatttt ttccgttctc attaatgtta aagatacaag gagagtagga
    11221 aaaaatcaaa caaaaaatat ttttgtaaaa tctatttaca aaaaaatttt tttgtataat
    11281 gagggtataa gaaatggagg cgctatcatg gaaattggtg taattggttt gggaaaaatg
    11341 ggattgaatt tagctttaaa cttaaaagag caccatcaca aagtacaagg actcgacatt
    11401 tcaagtacag ctgttagtca ggcaagagaa aatgacattc ctgcttatca agagatctct
    11461 gaatttctag ctacttttga gcagaaaaaa atcatctggt taatgcttcc tgctggagag
    11521 ataaccgaaa acatgttaag aaaacttttt ccaaaactcg gaccaggaga cattattatt
    11581 gaaggcggaa actcttatta taaagattca atccgtcgag cagaagagtt tcagaaaaat
    11641 gaaatcggtt acttggattg tgggacttct ggaggaatcg aaggagcacg acatcaagcc
    11701 tgcttaatga ttggaggaga taaagaaact tttctatccg tggaacaatt attcaaagat
    11761 gtagcaattg aaagaggata tctgtatgct ggtgcatccg gaagcggaca cttcttgaaa
    11821 atgatccata atggaatcga atatggaatg atgcaagcaa tcggtgaagg attccaactt
    11881 gtacaaaaaa gtgagtatgc ttttgacttg gaacaagtcg cacgtgtttg gaatcatggt
    11941 tcggtgattc gcggctggct gatggaaatc atggaagatc agttaaacga acatcccaat
    12001 ttaagtaatt atcggggaat cgtttctgca tcaggtgaag caaaatggac ggttgaaaca
    12061 gcgctagaaa tggctgttcc agttccagta attgcaacta gtttgttcat gaggaatctt
    12121 tcacaggaag aagatagttt ttcagcaaaa gtagtttcag cactaagaaa tgggtttggc
    12181 ggacatgaaa tagttgaaaa gggtgagtaa aatgccagat tatcatatag caatcgttaa
    12241 ttccagcagt ttcggaagag tctttccaca ccacttggaa agattaaagt cagttggaga
    12301 cgttcatttc tttactgttg atcaagagat tccaggaaaa gaactagcgg agttacttaa
    12361 aggattcaat atcattattg caagtgttac gccatttttt cgacgagatt tttttgaaaa
    12421 caaagatgaa ctgctattga tttcccgaca tggtattggt tacaacaata ttgatttaaa
    12481 agcagcaaaa gaacaccaga caatcgtatc tatcatacct gctttaattg aacgaaatgc
    12541 tgtagcagaa aataatataa ctaatttgtt gtccatgctt cgacgcacga cacaagcaca
    12601 agcaagagtc aaggacgatc gatgggaaga tcgggcggag ttcgtcggta ggacgctgtt
    12661 taacaaaaca gttggtgtga ttggtgcagg aaataccgga agcggagtaa tcgaaatttt
    12721 gcgtaacggt tttcgctgtg atgttctagc ttatgatcct tacaaatcag atttatacat
    12781 cgaaagcttt ggtgcaaaaa aagtagaact tcaagaatta ctggaacaat cagatatcat
    12841 ttgtttatgt gcgaatttga cagaagagaa ctatcacatg atttctgata aagaagtcga
    12901 tcagatgaaa gaaaatgttt atctatctaa tagtgcaaga ggcgctctag ttgatgaaga
    12961 agcgatgatt aatggtctga aaagcggaaa gatcgcagga tatgccacag atgttttaga
    13021 agaagaaccg ggacgtcaag atcatccgta tttagcgttt gaacaagtag tgattacgcc
    13081 acatatatcg gcctacacaa gggaatgttt agaagcaatg ggtgaaaaat gtgtcagaga
    13141 tgtcgaacag atcagtcagc accttcttcc tgaacgttct gtccagacaa agagcaacta
    13201 tataaaagga tgatgaagaa aatggtgaac ggtttaaaag tgaaaacagg ccctcaattt
    13261 tatttatatg aagaaggtgg tatttcaaaa gtttctgatc tcttgaaatc atacggcgcg
    13321 aaaagagtac tggtcaccca cggaacggta tcatgggaaa aggcgctacc taaattagta
    13381 tttttgaatg acgaaacgat tcaatttttt tatcatcgtt attctggaga atgtagttat
    13441 gctgaagcca gacgaatagc tacaatcatc aaaaaaatga aatcgatttc gtagttggcg
    13501 ttggcggagg aaaactgacc gatctagtgg gttatagtgc caatcttgca agaatcgatt
    13561 tcggagtcat ccctacttta gctagtaatt gtgctccatg gacacctctt gctgtcatgt
    13621 ataaggagaa tggacaagca gaagggaaaa cagaacactt ttacagacaa gctgcttttt
    13681 ttataacaga tccccaatta gtgattgatt cccctgttcc atatttcatt gccgggttag
    13741 cagatacact agcaaaatgg tatgaatctg agctcatctt agaacaagat tttttgcaag
    13801 atgaatcatt tttgaagcta gcacaagata ctgcgaagat ctgcaaagaa gagattttga
    13861 atcattctgc taaagcaatc caagatatgg cacaaagaaa actgacatcg gagttcaaac
    13921 agctttcaga gattatcttt gctgttgctg gtttagttgg aggattagga gataaatacg
    13981 caagaaatgc ggcagcacat gctatgcatg acgctatcag taaatatatt ccggaaagcc
    14041 atcgttttct acatggagaa aaagtagcgt atgggatttt ctatcaactg gcactagaag
    14101 gtcgctggga aaaaatagac gagttatatc ctttgtatcg ggaattagaa ctgccggttt
    14161 ctctagaaca aatgggatta tttccgaaag ataaacagat aatagataaa atggctgaat
    14221 ttattgattc gaaagagaaa gtgcatttga ttcctataga ggtaacacag aaatcactga
    14281 tacagtcaat gatggaactg gaaggttata tcagaaagat ctgaaggagg aggacacatg
    14341 gaaacattaa gtgtagtaca aagtttgttg attgctttat gggtagccgc ggttatgtcc
    14401 cgctggttag gtggaggagc cacgttgacc ttacgttttt ctcctttgat gactggatta
    14461 gtcgtcgggt tgatcatggg ggaagttgca caagcgatga ttgttacagc cgctttgcaa
    14521 atgatttata tgggggtttt ttctccagga ggatcaatgc cagctgaacc atctattgca
    14581 gcagctatcg cagtaccagt cgcattatta ggggatctgt cgccagaagc agcgattgcc
    14641 gttgcggtgc cagtcggatt gctcggaagt tacttgtatc agtttcgttt tttcatcaat
    14701 acttttttag gtaaatatac agacaaagct gtagaagatt tgaatacaaa agctatggcc
    14761 cgatcaatta ttctttatcc aacggttgcc tcatttttat tattcgttcc gcttgttttc
    14821 attgctttat atttaggggc gccattgatc gctgatgtaa tcaaagcttt agagggaaca
    14881 gtcgttatcc acattcttga agtagtaggt ggagggttag cggcaatcgg tatcgcgaca
    14941 actgtatacg ttatcggtcg aaaagattat ctggtctttt tcttccttgc ttattttatg
    15001 agtgttgttt tgaaatcttt agatattacg atggttactt atgccatttt tgggattatt
    15061 atcgctttga tctttgtcca gtcgcaaaaa gggaaacaag tacagcctgc cacaagcaat
    15121 aacaattcag catcttttga tgacgaagat gactatgatg acggatttta atttaggagg
    15181 aatgggaaat ggctgaaata atggataatc aaacaggtgc tcctgaagaa atcacgaaaa
    15241 aagatgtaac aaaagcctat ctgagatggc attttgcaaa cgaaattcct cactcttttg
    15301 aacgttactt ggcgccatca ctactatacg gaatgatgcc aatcttgaaa aaactttata
    15361 aagatgaaga ctctttaaaa gcagcatata aacggcagtt actgttcttc aacactcaat
    15421 taagctgggg tggcggtgtg attactggcc taatgtcttc tatggaacag caaagagcag
    15481 aagaagagta tgaagaaaaa gagatcttga tgcaggatga cttgatgtat aacacgaaag
    15541 cgggattgat gggggcacta gcaggaatcg gagatgcaat cgattcagga accgtccaat
    15601 atatttttat cgcaatcgcg gtaccttggg cacaacaggg aagtccttta ggcgcacttt
    15661 ttccttttat ctgctttggg ttgtatcagg ttttactagg ggtatttttc gcaagacaag
    15721 ctttcactat gggccgtaat gctacaggcc taatgcaaaa cactggtgtt cagacagcga
    15781 ttgaaatgct atcagtttta gggttgttta tgatgggggt gcttgcggga aactatgtaa
    15841 aagtagaatc ttcattgaaa tttgcgatat ccggacgtga gtttgttatc caggaaattc
    15901 ttgatcaaat cgtgccaggg atattacctt tagctgtcgt aatgggtgtg tacttgttct
    15961 atacgaaaaa aggattgaaa gtcacacaag cattattatg gctgactgga atattaattg
    16021 tgctagcagg aatcggtatt ttataaaaag aagggaacgt gaataagatg ggtgtagtca
    16081 atttagcgcg tgtggatgag cgtttgatcc atgggcaagt aatggtaacg ttatctcaaa
    16141 aaagtggagt gaattccatt tttgttgtag acgaagttgt agcaaaagat aaatttatga
    16201 gagatcttta caaaaatgca ggaagccgta caggacaaaa aacaattgtc attacaccag
    16261 agaaagctaa attctattgg gatgaatatc aatttaaaga atacaattgt attttgatcg
    16321 caaaaacagt ccaaacgatt tacgacttag taaaacacgg aatccccatg gaagaattga
    16381 atattggagg gattgctcaa aaaaatcctg atacagatct tttagtgacg aaatctgttt
    16441 atttaaataa atcagatgct gaaaaattga aagaaatgaa tgaacaatat ggcgtaaaga
    16501 atatttattt tcaagccact ccatctgcac ctaaaacagg attaaaagat gtattgaaca
    16561 agtttgattt gtcataaaca aatgcttaga aaaaagataa agagggcgaa aaaatgaaga
    16621 agaacgagct gtttcgtgat tgggaatttc gttatcgcta tatttaccgt aagcgccgta
    16681 caaaaaagag taaacagcgt tttctttcag cattagtatc agatatttac agtatgagaa
    16741 cagatgtgac agtcattgct tacgatacgc tagcctaccg atcaaaaaat atttatgttg
    16801 gagatatcga aaaagcagag aaagttatct gtacttatta cgatacaccc gttcatgcat
    16861 taggaagtta tttcatgttt gattggaaag accaaaggaa aaaaacaatc tactctatat
    16921 tattgtcctt cattttgttg ttcagtttag gttggtgggg aatgatgata tataacaaaa
    16981 atcctcatca cgtattcgat ctgctatccg tataaacagg tatcactgta ctagcatttg
    17041 ggagctactt tttcttattg ggaaaagcag ctcgcggatg gcctagcaga caaactttta
    17101 ttcgaaatac ttcatccata ttaacgatgc tagaaatgat ccgtacgatt gatgatccga
    17161 gtgtagcgta tgcgtttgtt gatgaaggct gttatggaga aaagggctta gacagcgtga
    17221 gatcgggtat gaaaaaagag gctattcttt tttatctaga ctctgttggg gcagatacac
    17281 cgctacagtt ttcgggaaat tatttttcaa ataaagaaca gtggctgaaa caagttgata
    17341 agttgaaaga aaaaaacgtc aattatattt ttagtgcaag aaaaaagcaa gcgcagttct
    17401 tctatttgac caaaacagat ttacgaggga aaacatttaa ttggcaaaat gccaatcaga
    17461 ttattgctct ttttcgataa gtaaaaagtg caaaacaagg agtgagaaga ctaatgttgg
    17521 aaatcatgat cgttacacat ggtaagttga gcgaaggact gaaagatgcg gcggaagtaa
    17581 ttgtcgggac atcgagccat attgaaacaa tgtgcttaga gtctggggag gacatccaaa
    17641 cattcggaga gaaggtcaaa gaaaaattaa ctatgatcaa cacagcagaa cccatgctag
    17701 tatttgttga tctaattagc gcaagtccgt acaatcaagc gctcttggca gtcaatgaac
    17761 tgactgaaga aaagaaagca gccacttatg tcataggggg cgtgaatctg ccaatgttgt
    17821 tagaagcaat caatcatcag atgcttcaca caccgataga agaagcggtg gaacaaattg
    17881 tcaaacaagg aaaagataat ttaactgttt ggcatgcttc agcggaagaa aaaaaattag
    17941 atgaggacga tttttagaag gaaggctgaa aagatgaagt ggggatttag atggtatggt
    18001 gaaaaagggg attcgatccc attaaaatat gttcgccaaa taccgggaat aaatgggata
    18061 attggaactt tgctgactaa aatgcctgga gatgtttggg agatttcaga aattgaggag
    18121 ttgaaagcat ctgttgagag ccaaggactg gaactgcttg gaattgaaag tgtagcgatc
    18181 cacgatgcaa tcaaggcagg gacagatgaa cgagattact atattgataa ctatatacga
    18241 acaatcaaaa acttgtctcg atgtggggtt cgattgattt gttatagctt caaaccaatt
    18301 tttggatggg cgaaaactga tttgtttaat gaaaacaacg atggaagcta ttctctttta
    18361 tacgatcaga aaatcgtcga tcagatggag ccaggagaaa tgtatcaatt gatacacagc
    18421 cagtcaaagg gattcaaatt gccgggttgg gaagaagaac ggttgaaaaa attcgctcag
    18481 ctggaaaaac tgtatgaagg aatgaccgaa gaagaattat ttgaaaatct gacttatttt
    18541 ttagaaaaag tgattccagt gtgcgaaaaa gcagatgtaa aaatggctat ccatccagat
    18601 gatccgccat gggaactttt tggttttcct agagtgacga aaaatcttgg cgacttgaag
    18661 aaaattctaa atgcagtaga ttctccatat aatggactaa cgctgtgcac aggatcttta
    18721 ggggcaaatc cggaaaacga tttagttgaa atcatccatg aggtaggttc gcgcatccat
    18781 tttgtccact tcagaaacgt ggagttttta ggagaaagaa agttcaaaga aacggcacat
    18841 ccctctacag aaggctccct tgatatgtat catattatga aagcgttggt gcaagaaggg
    18901 ttcgacggtc ctatacgccc tgatcatggt agaaccgtgt ggggtgaagt ggctatgcct
    18961 ggatatggcc tgtatgatcg tgcaatggga ctcacttaca tgcaaggtct atatgaggcg
    19021 ataagtaagg aaaaaccact gggagagcat tatgaataaa atcaagctct tcatctttga
    19081 tatggatggc cttttattag aaactggacg tttagcttat cgtgcttatg taaaatcagc
    19141 acaaaagtat gattatgaaa tgcgtaagga agtctattat ttactaactg gccaaacaga
    19201 aatggcgata agagaacaaa tgggcatttt gtacggagaa gatgttccat atatcaaatg
    19261 gcgagaagca atcaatcaat ataaagaaaa aatcgtgaaa gaagataaga gagtatatac
    19321 gaaaaaagga gcagaagaaa ttttatcttt tgcaaaagaa agaggaatcc atacaatcgt
    19381 ggcttcgtct aatacacggg taaaagtaga aatgtattta aaaatggaaa atctatatgc
    19441 cttgtttgat caaatcattt caggggatga tgtaaaaaaa ggaaagccgg aaccagagat
    19501 ctttttgaaa gcttgttcaa aaatgaatat tcctccaagt gaagcacttg tatttgaaga
    19561 ctcgattgca gggatcgaag cagcaaggcg agcgggcatt ttgtcttttc tcatcaaaga
    19621 tcatttgata gggttgcccg atcataatgg gaagcataag ttgaaagtag atgtaagttt
    19681 atatgaatcc aataaagcag actatgaatt ttatgacctg catcaagcaa aacgattttt
    19741 agaaagtaaa gggttgtatc tctaataaag aggactattt tctagtcctc tttatttatt
    19801 gtcctgcacg actgagggaa cagatgaaaa agaagtaatt ttttattttg aagtatctac
    19861 cttatttgta gtgaacaatt tagaacaaac acaaaacgca tctactgtta tctaccagta
    19921 gatgcgttta aagagaagaa cgagaatcgt ccatatgagg gtttccactc cttatgcaga
    19981 tttttttaat tcttgcactg cttgttcgat cgtaacacct gtcgctacat gattggtatt
    20041 ttctttgtca aaaacgacaa atagattcaa atctgtatcc aaggttactc gatattgtat
    20101 atctttgtta tagaatgtca tagccattct cctttcttta aatacttgct gaaaggcaac
    20161 gaacgcgttg ataacgaaat tccatttata agtataccac caattgaaag gttttcatag
    20221 ttaagaaatt ttaaagtcaa aagttgcaga taaaagcaaa taaacaagaa aacaaaaagt
    20281 gaatcaatcg cggttattca actttttctt cgattcgaag acaatagaag acaatgaatt
    20341 ttatatttca ttgcattatc cttgtgttat tagaaaaagc atgatatatt aaatgagtaa
    20401 tctattttga aacgtaattt gagcgatata tctacataga taaaactcct tttgcctatc
    20461 aaatatttat tgcaacgaaa aaacgtacat tgatacgtat caggaggaat ttatttatga
    20521 ataacggtac agtaaaatgg ttcaacgcag acaaaggttt tggctttatc actggtgaag
    20581 atggaaatga tgtatttgca catttttcag ctatccaagg tgacggcttc aaaactttag
    20641 aagaaggcca agcagtgtct tacgatgttg aagatggtca acgtggccct caagcaacaa
    20701 acattgttaa agcttaataa aaattgactt ttaaccgtct tttcgaaaga aaagacggtt
    20761 tttttgtacg aaaaaatt
//
LOCUS       DAZAOD010000048        20494 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000048 DAZAOD010000000
VERSION     DAZAOD010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.049"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            79..807
                     /gene="purC"
                     /locus_tag="ACHDPO_001688"
     CDS             79..807
                     /gene="purC"
                     /locus_tag="ACHDPO_001688"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFN3369309.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            807..1061
                     /gene="purS"
                     /locus_tag="ACHDPO_001689"
     CDS             807..1061
                     /gene="purS"
                     /locus_tag="ACHDPO_001689"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFN3369310.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1063..1734
                     /gene="purQ"
                     /locus_tag="ACHDPO_001690"
     CDS             1063..1734
                     /gene="purQ"
                     /locus_tag="ACHDPO_001690"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFN3369311.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            1735..3957
                     /gene="purL"
                     /locus_tag="ACHDPO_001691"
     CDS             1735..3957
                     /gene="purL"
                     /locus_tag="ACHDPO_001691"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFN3369312.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            3942..5381
                     /gene="purF"
                     /locus_tag="ACHDPO_001692"
     CDS             3942..5381
                     /gene="purF"
                     /locus_tag="ACHDPO_001692"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFN3369313.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            5404..6456
                     /gene="purM"
                     /locus_tag="ACHDPO_001693"
     CDS             5404..6456
                     /gene="purM"
                     /locus_tag="ACHDPO_001693"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFN3369314.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            6453..7031
                     /gene="purN"
                     /locus_tag="ACHDPO_001694"
     CDS             6453..7031
                     /gene="purN"
                     /locus_tag="ACHDPO_001694"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFN3369315.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7028..8563
                     /gene="purH"
                     /locus_tag="ACHDPO_001695"
     CDS             7028..8563
                     /gene="purH"
                     /locus_tag="ACHDPO_001695"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFN3369316.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            8579..9853
                     /gene="purD"
                     /locus_tag="ACHDPO_001696"
     CDS             8579..9853
                     /gene="purD"
                     /locus_tag="ACHDPO_001696"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFN3369317.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            9975..10889
                     /locus_tag="ACHDPO_001697"
     CDS             9975..10889
                     /locus_tag="ACHDPO_001697"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFN3369318.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11022..12587)
                     /locus_tag="ACHDPO_001698"
     CDS             complement(11022..12587)
                     /locus_tag="ACHDPO_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3369319.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(12580..14031)
                     /locus_tag="ACHDPO_001699"
     CDS             complement(12580..14031)
                     /locus_tag="ACHDPO_001699"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFN3369320.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14045..15061)
                     /locus_tag="ACHDPO_001700"
     CDS             complement(14045..15061)
                     /locus_tag="ACHDPO_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369321.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15281..16369
                     /gene="chvE"
                     /locus_tag="ACHDPO_001701"
     CDS             15281..16369
                     /gene="chvE"
                     /locus_tag="ACHDPO_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFN3369322.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            16423..17949
                     /gene="mmsA"
                     /locus_tag="ACHDPO_001702"
     CDS             16423..17949
                     /gene="mmsA"
                     /locus_tag="ACHDPO_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFN3369323.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            17951..19156
                     /gene="mmsB"
                     /locus_tag="ACHDPO_001703"
     CDS             17951..19156
                     /gene="mmsB"
                     /locus_tag="ACHDPO_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFN3369324.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            19413..20390
                     /gene="guaC"
                     /locus_tag="ACHDPO_001704"
     CDS             19413..20390
                     /gene="guaC"
                     /locus_tag="ACHDPO_001704"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFN3369325.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT         6572 a         3473 c         4692 g         5757 t
ORIGIN      
        1 attgctaaaa tttaaagtga aaaaacgaac aaaaaacgat gtatttgctt ttaatgtaaa
       61 taaaaaggag agacgtacat ggagaagaaa gaacttttgt atgaaggaaa agccaaaaaa
      121 atatatctta cttctgatga gaacttgatt tggatagaat atttagatca agcaactgcg
      181 ttgaatggcg cgaggaaaga ccagataagt ggaaaaggag aattgaataa tcaaatcaca
      241 agtgcaattt tccgttatct gactcaaaga ggaataaaaa atcattttat tgaacaattg
      301 tctaaaaccg aacaattagc aaaaaaagta caaattatcc ctctggaagt ggttatccga
      361 aatattgcag caggaagttt ctcaaaacgt ctaggtgttc ccgaaggtaa agaattcatc
      421 aaaccaatca ttgaattcta ctataaggat gaccagttgg atgatccatt tatcaatgaa
      481 gagcatatct atttcttaca acttgcaaag ccggaagaaa tcagtgagct gaaagcccaa
      541 gcgttggcta ttaatgaaat tttgaccgaa ttatttgcta aggtcggttt ggttttagta
      601 gatttcaagc tagaatttgg ccggtcgaat ggacaaattt tgcttgcgga tgaagtaaca
      661 ccggatactt gccgattatg ggatgaacgt acgaatgaac atatggacaa agacgtttac
      721 cgcagagatc taggtgattt gatcccagtc tatcaagaag tatataaccg tctatcggaa
      781 ctaactgaag aaaaggagcg agtatgatgt atttcgtaaa agtatatgta acctataaag
      841 attcagtgtt agatcctcaa ggggaggcag taaaaaaagc agtccatcgt atgggatatg
      901 aaacaatcga agatatccga ataggaaaat actttgagat acaacttgct gatgcagaag
      961 aaccaatcga tacagtgatt gaaacgattt gtgacaagct gcttgcaaat gtaaatatgg
     1021 aaacataccg atatgaaatc aaaaaaatgg aggaagtata acatgaaatt tgcggtcatc
     1081 gtttttccag gttcaaattg tgacgcagat atgttatggg cagttcgcga gatcatgggc
     1141 gctgatgccg aatttgtacg gcatgatgag tcctctttag aaggatttga tggggtttta
     1201 ctgccgggag gattctccta tggtgactat ttgagatgcg gtgcgattgc tcggttttct
     1261 acaatcatgg aagaagtgat tcgttttgct gaagaaggga aaccagtatt cggtacatgc
     1321 aatggattcc agatattgac agaagcagga cttttgccag gtgtactgag acgaaatgag
     1381 tctttgcatt ttatttgcaa aactgtacca ttgaaagtca accccaagac ggcctttact
     1441 tcagagtatg aagccgacga aataatctat cttccagttg ctcatgggga aggaaattat
     1501 ttctgtgacg aagaaacact tcaagaacta aaaaaaaata atcagattgc ctttacttat
     1561 aatgacaaca tcaacggcag cgtggaaaac attgcaggga ttacgaacaa agcagggaat
     1621 gtgttaggaa tgatgcctca tccagaacgt gcagtagaag acttgctagg atcagaagat
     1681 gggaaacggt tctttgcttc cattttaaaa aacttcggaa aggtgaccgt atagatgaaa
     1741 acattgaaag aaccgacagc tgaagagatc aagaaaaaaa gaatctatgc cgaatgggga
     1801 ttgactgatg aagaatatcg aatgatcgaa gaagatatct taggaagaat gcctaattat
     1861 acggaaactg gactgttttc tgttatgtgg agcgaacatt gttcctataa aaattctaaa
     1921 ccggttctac gcaaatttcc tactagtgga cctcatgtgt tgcaaggccc tggagaaggc
     1981 gcaggcatcg tcgacatcgg tgatggacta gcagttgtct tcaaagcaga aagtcacaat
     2041 catccttcag ccgtggagcc ttatgaagga gctgcgacag gagttggcgg aatcatcaga
     2101 gatattttca gcatgggggc tcgtccaatt gcgttgctag attcattgag gttcggcgaa
     2161 ttagataatc caagaacgaa atatttacta gaagaagtag ttgcaggtat cggcggatac
     2221 ggcaattgta tcggcatacc gactgtaggc ggcgaaattg catttgatcc ttgttatgaa
     2281 ggaaacccat tagtcaatgc aatgtgcgta ggtttgattg aacacaaaca tatccagaaa
     2341 gggcaagccg ctggcgtcgg taattcgatc atgtatgtag gtgcaaaaac aggtcgcgac
     2401 ggtatccacg gagcaacttt tgcctcagaa gaatttaatc aagaagaaga acagcaacgt
     2461 tctgctgtac aagtaggcga tccttttatg gaaaagctgc tgcttgaagc gtgtttggaa
     2521 ttaatcttgc atcattcgga ttctctaata ggtatacagg atatgggagc agcaggactt
     2581 gtttcatcta gtgcggaaat ggcttcaaaa gctggctcag gacttatatt gacattagat
     2641 gaagtcccac aaagagaaac tgggatgaca ccttatgaaa tgatgttatc ggaatcacaa
     2701 gaacggatgt tgatttgtgt taaatcagga gaggaagaaa aaatccaaga actatttcag
     2761 aagtatgatc tagatgcagt cactatcggt aaagtaacag acgacgggca atatcggcta
     2821 tatcatcaag gagaagaagt agcaaatctg ccagtcgatg cattagctga agatgcacca
     2881 gtttatcata aagaaatgaa agaaccagct cgaatcgtag aatttcagca gttagctcct
     2941 tatcagccag ttatcgaaga acctggacaa gtattgcttg atctgctgca gcaaccgacg
     3001 attgcttcaa aacgttcaat ctacgaaact tatgattcac aagtacaaac caatacagtt
     3061 gtccgtccag gaagcgatgc tgctgtgatg agggttagag ggacgaataa agcgttagct
     3121 atgaccacag actgcaacgc gcgctatctg tatttggatc caaaaatcgg aggacaaata
     3181 gcagtggcag aagctgctag aaatattatt gctagcggtg gtaagccctt ggcgatcacc
     3241 gactgcctga actatggttc tcctgataaa ccagaagttt tttgggaatt atcgacttca
     3301 gctgacggaa ttgctgctgc gtgtgaaacg ttaggaactc ctgttatttc aggaaatgtc
     3361 tctttatata atgaaacgga tggtcaagca atctatccaa caccaatgat tggtatggtc
     3421 ggattgattg aggatcataa acatatcact actcaggaat tcaaaaaatc aggggatcta
     3481 atctatatat taggtaagac gtttgcagat tttgatggca gtgaattaca aaagatgcag
     3541 cttggaagaa tcgaaggtgt gatccgaaac tttgatctat ccattgaaaa gagaaaccaa
     3601 gagttagtat tgacagccat ccaaaacgga ttgattgaaa gtgctcatga ctgttcagaa
     3661 ggtggcttgg caattgcact ggcagaatca gctttcaaac atcagctagg gatatctgta
     3721 cagtttgaat tgtcctctgc tcaattattt gcagaaactc aatcaagatt tgtgttgaca
     3781 gtcgcaccgg aaaataagac acgattcgaa gaaatgatgg gagatgctgc tgttttagca
     3841 ggtaaggtga cggatgaagc gataatcgaa atttcagcaa ctgacggtca gatcaaaata
     3901 gaaactgcag tagcaagaaa gtgctgggag gatgcaatcg tatgtcttat gaagtgaaga
     3961 gtttaaatga agaatgcggg atcttcggtg tttggggtca tccagacgcc gctagtgtgg
     4021 catacttcgg gctccatagt cttcagcatc gaggacaaga aggtgcaggt atcgtgtcca
     4081 atgatcgagg aaagcttaag gggcatcgag atttggggct gctttctgag gtattcaaag
     4141 atcaaagaaa attgcagcag ttaacaggag aagctgcaat cggacatgta cgttatgcaa
     4201 cagcaggcaa tggaagtgtg gacaatattc agccttttct attcaaattt catgatcagt
     4261 cgatcggctt agcgcataat ggtaacttga tcaatgctcg ttcccttaga aaagagttag
     4321 aggaaaatgg ggcgatcttc cattctaact ccgatacgga gatattgatg catttgatcc
     4381 gacgaagtga agaaacagat tttttaaata aattaaaaag tgctttgaat gaagtcaaag
     4441 gtggctttgc ctatttatta atgacagaaa cggcaatgat tgccgctttg gacccaaatg
     4501 gttttcgtcc attagcaatc ggacaaatga aaaacggagc atacgtgatt gcctcggaaa
     4561 cttgtgcatt agaagttatt ggggcacgtt ttataagaga tgtccagcct ggtgagatag
     4621 tgatcatcaa tgacgaagga atccagattg attgctttac gaaggacacg cagctttcta
     4681 tttgttcgat ggaatatatc tattttgcca gaccagattc aaacatcgca gggatcaatg
     4741 tgcatactgc acggaaaaat atgggacgga atttagcgaa agaatcgcca gtaaaagcag
     4801 atatggtcgt tggcgtacct aattcttctt tgtcagccgc aagcggttat gcggaagcta
     4861 gtggaatccc ttatgaaatc ggattagtaa aaaatcaata cattgcccga acatttatcc
     4921 agccaacgcc tgagctaaga gagcaaggtg ttcgaatgaa attatctgct gtacgaggag
     4981 tagtggaagg taaaaaggtg attatggtcg atgattcaat tgttcggggt acgacaagca
     5041 gacggatcgt ccatcttttg aaagaagcag gggcaaaaga agtccatgtg aggattgctt
     5101 ctcctccttt gaaatatcca tgtttttacg ggattgatat tcaaacgcgt aaagaactca
     5161 ttgcggcaaa tcacacgatt gatgaaatca aagaatgtat cggtgcagat tctttaggtt
     5221 ttttaagtga agagggtctg atcgaatcga tcggtctgga aaaagatgct ccgtattcag
     5281 gattgtgtat ggcttatttc aacggagatt atccgacgcc gttatatgac tatgaagaaa
     5341 aatatcagga atcactaaaa gaaaaagtat cgttctttta aaagcagacc aagaagggag
     5401 tatatgaatt caatggcaaa tgcatacgca aaagctggcg tagatgtcga agctggatat
     5461 gaagtagtag aacggatcaa gaagcatgtc aaaaaaacgg aacgtttagg tatgatgggc
     5521 gctataggag gattcggcgg ttgttttgat ttatcggtct ttcaattaaa agagccagtc
     5581 cttgtctcgg ggaccgatgg cgtggggacg aaattagcag tggcaatcga agcagacaaa
     5641 cacgatacaa tcgggatcga ctgcgtagcg atgtgtgtca atgatatctt agcacaaggc
     5701 gcagagccgt tatatttctt agactactta gcaacgggga aaaatgatcc gttacgtttg
     5761 gaaaatgtag taaaaggtgt agcagatgga tgtgttcaag gaaatatggc gctgattggc
     5821 ggagaaacag ctgaaatgcc tggtatgtac tcaggtaatg attatgatct agccggattt
     5881 gctgtaggga tagctgaaaa atctcaatta ttgacaggag aaacgatcaa cccaggagat
     5941 gtgttgcttg gaatagcatc tagcgggatt cattcaaatg ggtactctct tgttcgcaaa
     6001 attttctttg agcagcagca gttttcttta tcatcaaaac tgccagaatt gaaaaaaaca
     6061 cttggcgaag aattgcttga gccaacgaaa atctatgttt cttccttgct tccgctgatc
     6121 aaagaaaaga aaataaaagg agctgcacat atcactggtg gagggtttgt agaaaatatc
     6181 ccgcgaatgt taccagaatc tatggctgca caaatcaaac ttggctcatg gccgattctt
     6241 ccaatattcg gctgtttaca aaaatatggt gaaattcctg agatggagat gtatgaaatc
     6301 ttcaatatgg gcatcggtat ggtcctggca gtccaagaat cgaaagtaaa agaaatagta
     6361 cacgaaattg agcaagctgg cgaaaaagtt tatgaaatcg ggaaagtgat cgccaaagaa
     6421 aaacatcgtg tggtgtttat aggagaagaa cgatgagaat cgctgttttt gcttctggaa
     6481 acggaagcaa ctttcaagcg ctagccgatt atctatcgaa aaaaggattg gaatcttcga
     6541 ttgactggtt gttttgtgat cagcctgaag catatgtttt gaaacgtgca actgcgttga
     6601 gtgtaccggc agattgtttt tcacctaaag aatttgattc aaaaaaagag tatgaagaag
     6661 caattttgca taaattgaaa gaaaaaaaga tcgatttgat cgtattagct ggatatatgc
     6721 gaatcattgg accggtattg ctgaaaaatt atgataaaag aatcatcaat atccatccgt
     6781 ctcttttacc tgccttccct ggtttgcatg gcatacgtga tgcctttgaa gctggagtaa
     6841 aagaaacggg tgtcacaatt cattatatcg accaaggtgt agatactgga ccaatcatcc
     6901 ggcaggaaaa agtgagaatt gaacaggagg acacgttcga ttctttagaa gaaaaaatcc
     6961 atagagtaga gcatcgaatc tatccagaag tgattagtga aattattgaa aatggaggct
     7021 atctgaaatg acaagagcat tgatcagtgt atcagataaa actgggattg tagcattcgc
     7081 ccaaggtttg attgaacaag gagtagaaat catttcaaca ggaggaacaa agcatgcgtt
     7141 ggataaagct gggatcaaaa cgctttcgat cgaagaagtg acagggtttc ctgaaatgat
     7201 ggatggccgt gtcaaaacac ttcatcctaa aatccatggt ggtcttttag gaagacgcga
     7261 tctccctagc catatggagg caatggaaac ggaaaatatc caaccaatcg actttgtttg
     7321 tgtcaattta tatcctttca aagaaacgat tatgaaacca gatgtcgaaa tagcagaagc
     7381 tattgaaaac attgatatcg gtggtcctag tatgctccgt agtgcagcaa aaaaccatga
     7441 atttgtcacc tctgttgttg atccatctga ctatgaagaa gtactttcag aattacgtca
     7501 gtatgggcat acttcacttt ctttcagaca aaaactagcg gcaaaagtct ttcgtcatac
     7561 tgcggcatat gatgcactga tcgctcaata cttaacggat tgggtggaag aaaaagaacc
     7621 ggaaaaattg acacttacgt atgaacgaaa acaaacgctt cgttacggtg aaaatagcca
     7681 tcaagccgct gccttttatc agtccgctct tctggaaaaa tattcgatcg cagcagcaaa
     7741 acaactccat gggaaagaac tttcttataa taatatccga gatgcagatg ctgcgctacg
     7801 gatcatgaag gaatatgacg agccaacggt agtcgccttg aaacacatga atccttgtgg
     7861 tattgggaca gcatctacga ttttagaagc gtgggaagca gcgtatgaag cagatcctgt
     7921 ttcaatcttt ggtgggatca tcgttttgaa tcgagaagta gatctgccaa cagcagaaca
     7981 gatgcataag ctgtttctag aaatcatcat tgccccttct tatacacaag aagctttgga
     8041 attactgcaa aaaaagaaaa acatccgatt actgacagta gactttgcgc aggaagaaaa
     8101 tcaaaatcga gaagaaacgg tctcagtctt aggtggactt cttgtacaag atcaagatct
     8161 ggcaatagaa aatgaagaag agtggaaagt cgtgacaaaa cgtaagccga ctccagcaga
     8221 agcaaaagca ttagcgtttg cttggagagc tgtcaaacat gtgaaatcta atgcgatcgt
     8281 actggcaaac gaacgtcaga cagtaggaat cggagccggg cagatgaatc gagtcggttc
     8341 agtaaaaatt gcgattgaac aagcgcaaga gaaaatggaa ggtgcagttt tagctagcga
     8401 tgcttatttt ccaatggatg attcggttga atatgcagcc aaacatggta taaaagcaat
     8461 cattcagcca ggaggaagca tcaaagacca agattctatt gatatggcga ataaatacga
     8521 tctagcaatg gtctttactg atgttcggca ttttagacat tagagaggag tcggataaat
     8581 gaacattttg gtgatcggtg caggtggtcg tgaacatgca ataagtaaaa aacttttagc
     8641 cagtccgaag gtggatacgg tgtattgtgc gccaggaaat ccggggatga caaaagatgg
     8701 tatcaattgt gtcgctatca gtgagcgaga tcattcagcg ttaatccatt ttgttaagaa
     8761 agaggctatt gattggagta tcgttggtcc tgaagttcct ttgttaaatg ggatcgtcga
     8821 tgattttatg gcggaaggat tgaaaatctt cggtccgaca aaagcagcag ctctgatcga
     8881 aggttcgaaa agttttgcta aacaattaat ggatacttat caaatcccga cagctaaatc
     8941 cagaagtttt gaatgttacg aaaaagcagc agcgtatatc aaagaaaatg gtgcgccaat
     9001 cgtagtgaaa gcggacggct tagcagctgg gaaaggtgta gtcgtggcta ccacagtgaa
     9061 ggaagcgctg gatgcggcag aacaaatgtt gaaccagcat cgatttgggg atagtagcaa
     9121 aaaaatcgtc gtagaagagt ttttggcagg agaagaattc tcccttttgg cgtttgtccg
     9181 taataccaag gtgtatccga tggtcatttc gcaagatcat aagcgggcat ttgataacga
     9241 taaagggcca aatacaggcg gaatgggtgc ttattcacca gtaccgcaaa tttcaaaaaa
     9301 gatgattgaa aaagctgtgg aagaagtttt aaaaccagcg gctttgggaa tgaaagaact
     9361 aggacgctct ttcacgggtg ttttatatgc gggtttgatt gctacgaagg aaggaccaaa
     9421 agtgatcgaa ttcaatgcgc gtttcggtga tcctgaaacg caagtcgttc tttctcggtt
     9481 gaagagtgac tttgcgcaag taatcgatga tttattagag aatcgtacag tagagttaaa
     9541 gtggcagcaa gaaggataca atgtaggcgt tgtggttgca gctgccggtt accccgaaga
     9601 atatgagaca ggaatggttc taccagattt tctggaagaa gagctttctg tttactatgc
     9661 tggagtttcc tcaaataacg gcaaactagt tggagcagga ggacgtcttt atttagtaga
     9721 agcatacggt gagacgatca aagaagcaca gaaaaaaatt tacaccgcgt taatggataa
     9781 aacgacagat ggaacatttt atcgtacaga tattggagaa aaagctgcca atagcgaact
     9841 gatcgtgaag taaatcagct gcttccattt ataaaaaata caacaaacat aatcggaagc
     9901 gccgatttta gtgaagcctt ttcataaaga gtgtggtaca cttttgttgt gtatataaat
     9961 aaggaggagt tcagatgaaa aaaattcaat taggtacttc tgatcagaaa gcagctgcag
    10021 tgatcttagg ctgtatgcgt atcaacaatg cggaagatcc agtaaaagtg attgagacag
    10081 cttatgaaaa cggcattgat ttttttgacc atgcagatat ttatggaaac ggtgaatgtg
    10141 aagaaatctt tgcagatgct ctagcaaaaa catcaatcaa acgagaagat ctttttattc
    10201 aaacaaaatg tggaatcgtt ccaggtgtga tgtttgattt ttctaaaaaa catatcattg
    10261 aatctgtaga aaaaagtttg acccgtctga aaatggatta tgtggatgct ttacttcttc
    10321 atcgtccaga tacattggta gaaccagagg aagtagctga agcgtttgat gaattggaac
    10381 ggtcaggaaa agttcgttat tttggcgtca gcaatcaaaa accaatgcaa atcgaattgc
    10441 tgaaaaaata tgttcgtcaa ccattagtag ctaatcagct gcaatttggc ttgaaacata
    10501 ctggaatgat cgatcaaggg attcatgtca atatgacaga tgaagcaagt atcgatcatg
    10561 acggtagtgt acttgattat tcccgattgc atgatatgac gatccaagca tggtcaccat
    10621 accagtatgg attttttgaa ggtgtattta tcgggaacga aaaattccct gaattaaacc
    10681 aaacattaga agaactagca gctaaatatc aaacgacacc aactggcttg gcttctgctt
    10741 ggattttacg ccatccagcc aatatgcaag tgatcgccgg tacgatgaac gtagggcgaa
    10801 tcaaggaaat cgctcaagct tcagaaatta atatgtctcg ggaagattgg tacgaattgt
    10861 accgtgctgc tggaaacatt ttaccttaaa gattgtcata agcaggtcaa aagggctata
    10921 aattaaaaag acagaataac ttgaaagctg ttttcagctt cgagatattc tgtctttttt
    10981 tattgcaaat ggaaagagta tcattgtacg gatttcgttt attagttatt tttgttttta
    11041 aggaaaagct gtgtccgata ttcttttgga gaaatccctt gttttttctt aaataaataa
    11101 ctgaaatagt tagggtcatt ataaccaatt tcaaaagcaa tatctgaaat acgatagtct
    11161 gattgctgca ataatttttt tgctaattcg attctttgtt ctgtcagata atcgatgaat
    11221 gtttggttaa acgattgaga aaaaatcgta ctgaaatgag agggacttaa tgcaacttgt
    11281 tgagcgaccc aagttaagga catatctgga tcggtaaaat tttctttgat aaaatccaat
    11341 gcatggttca aaattggctg atatttgttc cttgaaggct gtgagggcag agcagttaag
    11401 aaagaaatga acatataaac tgtcgaacgg taaagcgagt cgtcggcgct gattgctaag
    11461 cgttgactgg tggatgtgca atgaaccatt tcttgcggga ttttcttttc tttcaggcag
    11521 acatgctgga gtagcttagt caagacaaat aaacgatata atcgtgttcg agttggtgtg
    11581 ccttgtggtt tcgtcaagtg ttcgatgtac ttagatactt cgtttttcga taatgaagac
    11641 aaatcaagtg agaggtcaaa gtaaaagaca gaatcaactg gaagtttcgc ttcttgaatc
    11701 aaatcctcat agctgataat ttgttcttta agggaactgg cggtttcaag tatcatctgc
    11761 gtgatctcaa aagatgcagg taattcgctg attctttctg cgacaggacc aatggcgaca
    11821 gaaaaattat ttttttgtcc cttttctaat tcatggacca acgtttgggc tacctgataa
    11881 ctggtctcga tcacattttc ttcaagagaa tcaactatta aaaatttgat gaatcgagag
    11941 gaaacagcag agaagatcac ttgttgattc tccctaaata aaaacttcaa ataatcactg
    12001 agatgagcgt aatcttcaaa gtctgtactg acttggtttg ctgctaataa tacggtcatt
    12061 tttttccctg ctaaagagcg attgaaagat tcagcaagtt tcaatgtttc actgatcgta
    12121 agtgagcctt tgaacaaacc gttcaagaaa tgattttttt tcaattcgaa aacaagatca
    12181 gaagaagtgt gcgtttcttt ttgctgcaaa tctaaagcag ttactgcttt ttctattgct
    12241 tgtttcaatt cgctactttt aatcggttta agcagataat catctgcctg tacctggatt
    12301 gctcctttca tataatcgaa atcgtcgaat ccactaataa atatgagacg agtccaagga
    12361 agtagtttcc ttgcttcttt tgaaaaagtc aacccgtcca tgaaaggcat ttggatatca
    12421 gtcagaatga tgtcgggctg taagtcgata attgaagaca gtgccatctc accatctcca
    12481 gcttcgccga cataagtgat tggataataa gaaccaagga cagttatttg ttcccgcaag
    12541 ttattgcgaa tgaggtattc gtcttcgatg ataaaaactt tatacatgtt tgtttcctcc
    12601 aattgttttg ggagatagag ggatcatcag tgtgacagtt gttccttctc ggtatttgct
    12661 gtcaatcgtg ataggttttt gatcatttcc gtaataaaga aggagacgct tgtttacgtt
    12721 gtaaagtccg tagccgatac tgaaatctga atcgatccct ttggctaact ctttacgtat
    12781 ttctgccagt ttttctgcag ggatgccaat cccgttgtct ataactttga attggatcat
    12841 ctcatcaatt ttgcatgtgg taatacgaat aaatcctttg tgacggacgt acttcgttcc
    12901 atggtataca gcattttcaa tcaatggctg caagatcatt tttaaaatag aaacaggaaa
    12961 aagtgtttct ggtatatcga tcttatagtc aagcatatgg ccgtatctta tttttaagat
    13021 gactagataa tcattgatat ggctaatttc tttttcaaga ggaatccagt cttgtccttt
    13081 gcttaaagac gtacgaaaaa agccggaaag tgcatgggtc atagtcagag cttcttcaaa
    13141 gcagtcttgt tcgatcaaag aaataatggc atccaaactg ttataaataa aatggggagt
    13201 aatctgagct tgcaatacac gaacttcact ttgtgctaaa tggtattgtt tcaaagcgtt
    13261 ctcccgtaaa gactggttta gatcttccgc cattttattc atgctagcgg taagtgtttg
    13321 taattccagt gtttccggca gggttaaacg aaagccaagg ttccctgaag aaagttgttc
    13381 tgacatctcg atcagctgat tgatcggttc ttggaccttt ctctctaaaa agcgacgatt
    13441 ctttttcgca tagaaaaaaa tggtactaag aactccaagt tccactattg ttaatagaat
    13501 gagcgagcgg acaagtgtcg tatttttttt gcttgctaag tcgatctcca cacgaacaaa
    13561 atcttgtaag atatctgaca gcagttgagt gacagaatct acctgattga tgatctcttc
    13621 attggtatcc ataaaatctt ttgccaagat attattgatc agctcgtttt gataatcttc
    13681 cagtgtatcg atcgtacgta gcgatacatc taacgtacta atttctttaa gtgtatttgt
    13741 attatttttg atctctcgaa tatcattcct aagttcttct aggatatttt cctcattgaa
    13801 ctcatctacg gttacttggc cagaaatcaa gtcccacata ctttccaaaa ctttttgatc
    13861 aaccttcaaa gcaattgcat ctgctttttg gatatttgcg atcgtctgtt gataaatcaa
    13921 aagctgttgc gaatataaca gtatgctcag tagcaaaggg ataacagcaa atagaagcat
    13981 ggctttgttt gcttgggcaa aaatctgttt tatgcttaaa ttttttgtca tgatacttct
    14041 ccagtcaata atttctggtt gggatgttag ctatattctg ctgggaaaag acagtctcgg
    14101 aaataaaaat atctttaggt aatgtttttc ctgtttgaat atttccaaaa taacgagtaa
    14161 cggtattggc tacataccag ccgacatcag gtttacactc gactacacaa ttgacgattc
    14221 ctgagcgtag cttctcgatc atatcttctt gtccatcaat agttacaatg atcaaatctt
    14281 ctccaggttt gattgatgtt tcttttatcg cagctaaagc accgtgagtc atttcatcac
    14341 tatggctgta taatacatcg atttcggata aatcatttgt ttctaaatat cgtttcatct
    14401 ggtcttttcc tttcatccga ataaaatcac cgacaattcg gtgaacaata gtcatcggag
    14461 gtttatggtc gatggttcca tcttttttta gggttggttt acgattgatt gattccaaaa
    14521 atccttcgga gcgtagcttg gtcggtgtgg agttctctga accagcaagt tctaggattc
    14581 tgatttcctg tttctttgaa tttgtgaagt gattgctgac aaataaaccc gcccgatttc
    14641 cttctgcttt gaaactgggg ccaatgtggg tgacgaaaag ctcgggatca ttcgtttgaa
    14701 tatgtctgtc gacaagtatg acagggatcc ctgctcgctt tgcttctttt aatacagagt
    14761 cccacccgga ttcttgcaaa ggagtaaaaa tgatcatatc cactttatag gcaatgaacg
    14821 tccgtatatc ttggatttgc cgttcctgat tcatgtagcc atttcggtag agaacttggt
    14881 aatcttcttt ttcaagcgca gtgataattg attcagtatg ctttttccgc cagctactct
    14941 ccgttcctga ttgcgaaaaa ccaacgacta gtgggtcagg tgcttccttt gtattaggtg
    15001 tacaccccat catttggtaa gcgattacaa caagggctaa aaaaaataaa acacgtttca
    15061 ctttaaatca ctccatctgg atttgttagt actatcttat cagataaaag ggaaaatcaa
    15121 agtcaaaagg aatcaatcga aaaaaatcca agaaacttaa aaaaatccaa gacaaaaaaa
    15181 gtacacctaa aaaatttaaa gtaaatccca taaaaaaatc aatgttaacg ctttctttat
    15241 tagctatact cggtgtatca attgaaatgg gggataaaaa atgaaaaaca aatttagaaa
    15301 gattgttggg actatcgcta ttttgaccgc aagcattcta ttaagtgcgt gtggcaattc
    15361 aggatctgca gatgatagta cggggtatgt aggaatcgct atgccgacca aatcagcaga
    15421 aagatggatc gctgatggga acaacatggt ctcggaatta gaaaaactgg gttataaaac
    15481 agatcttcaa tatggagaag ataaagtaga aaatcaagta gcacaaatag aaaatatgat
    15541 tacaaaaggg gtagatacac ttgtgattgc ttctatcgat ggttcggctt taactgatgt
    15601 gttagctaaa gcaaaagaag cagatatcaa ggtgatcgcc tatgatcgtt tactgatgaa
    15661 ttcagaaaat gtcgattatt acgcgacttt tgataatttt ggagtaggtg tatcgcaagc
    15721 agcttatatt gaagagcact taggattgaa agaaggaaaa ggaccattca cgattgaatt
    15781 atttggtggc tcgcctgacg acaacaacgc actaatcaat tacaacggag tgatgtctgt
    15841 tttacaacca tatatggaca acggtcagtt ggtcgtgcca tctggacaga cgagtttcag
    15901 tcaaatcgct acgcttcgct gggatggttc tacggcgcaa gcaaggatgg ataatctgtt
    15961 aagcgcaaat tatactgacc aaacattgga tgctgttttg tcgccatatg atccaataag
    16021 tttaggaatc atttcgtcat taaaaggcgt ggggtatggg agtgaaagta aacctttacc
    16081 tgtgattact ggacaagatg cgacagttgc tggcgttaaa tcgatcattg ccggggaaca
    16141 aacacaaacg atctttaaag acacacgtat cttagcaaaa aatacgattg aaatgatcaa
    16201 agcaatcagt gatggagaag aggttccggt caatgatact gaaacttatg ataatggggt
    16261 gaaaactgtc cctacgtatt tagcaaatac agtatctgtc gataaagata attatcaagc
    16321 agagctgatc gacaccgatt attataaaga atccgatctg aaaaattaag aggaaccaaa
    16381 caaggaacta aagagatcta agtcagagag aggataagaa ttatggcgga ttgtatttta
    16441 aaaatggcag atatcaccaa aaaattttct ggaatccgag cgttagattg cgtgaatctg
    16501 atgattgaac gtggggaaat ccatgcattg tgcggagaaa acggagcggg aaaatcaaca
    16561 ttgatgaatg tcttgagcgg cttgtatcca tatggctcct atgacgggga aatcttttat
    16621 gatggaaagc tgtgtcaatt taaagatttg aaagatagtg aagaaaaagg catcgtcatc
    16681 attcatcaag aattagcact aagtccttat ctttcaataa aagagaatat ttttctcgga
    16741 aatgaacaag cagaaagagg cgtgattgat tgggaactga cagaaaagaa aacatatgaa
    16801 ctgctgaata aagtcggttt gtctatcgac ccgaatcttc tagtatccca gattggcgta
    16861 gggcaacagc aactagttga aatagctaaa gcattatcaa aatccgtccg tctgttgatt
    16921 ttggatgagc ctaccgctgc attgaatgaa gaagaaagcg cgaatttgct gagattgatc
    16981 cgagagttga aagagcaagg tgtaacctcc atcattattt cacataagct gaatgaaatc
    17041 gtggatatcg cagatcgaat caccatttta cgggatggac agacgattga gacactagaa
    17101 aatgaaatga tcagcgaaga gcatattatt cgcggaatgg tgggcagaga tttagttgat
    17161 cgttatcctg aaagaaaacc ggatattgga gaagtttatt ttaaagtaga agactggacg
    17221 gtctatcacc ctcttgatca cgagcgaatc ataaacgacc acatcaactt gcatttgaaa
    17281 aaaggagaga ttgtaggaat agctggactg atgggagcgg gcagaactga attcgctatg
    17341 agtctatttg gacattctta tggaagcaag atatccggac gtatattaaa ggaaggggca
    17401 gagatatcag ttaagaccgt tccttcagcc attgcaaacg gactcgctta tgtctcggag
    17461 gaccgaaaat ctttaggact gaatctgctg atggatattc gggaaaacgt gacgctgagc
    17521 agtttggata aaataagtca aaaaggagta ttagataaag aaaaagaagt aactgaggca
    17581 gaaaatttcc ggaaaaagat gcgtataaaa acaaactcca tccatcaaat tgtcagtagt
    17641 cttagtggtg ggaatcaaca aaaagtcgtt ttatccaagt ggctgatgac acaacccgat
    17701 attctttttt tggatgagcc aacccgtggg atagatgttg gggcaaaata tgagatctac
    17761 acgattatcg aagaaatggc agcaaatggc aaagctgtct gtcttatctc ttctgaactt
    17821 cctgaaatat tagggatgtg tgatcgaatc tatacgatga acgaaggacg tattacagga
    17881 gaagtctcgc gagaagatgc agatcaggaa gtcttgatga aattaatgac gaaagaagag
    17941 gtgggttaag ttggaacagg caaaaaatct tacggataaa aaagagaaaa aactaaattt
    18001 gaaaagtaga gcagctgatc tttttggtcg ctacagcatg gtgatcattt tagcgggact
    18061 acttattgcg tttcaattga tgacggatgg tattttctgg cgtccattga atataactaa
    18121 ccttgttctg caaaatagcc atatattagt actagctgca gggatgttat tagttgtgct
    18181 cttaggtcat gtggatttgt cggtagggtc agtgatggcg tttgttggtg caattgcggg
    18241 catgatgatg gtcaatcgcc aaatgaaccc gtggatgaca gttatcgcat gtcttgcagt
    18301 aggcgggctg atcggcgcat ggcaaggttt ttgggtagct tatgcaggga taccggcgtt
    18361 tatcgtgact ttagcaggat tgctgatgtt tcgtggactg acacaagttg ttctaggagg
    18421 ccaatctcta gcaccttttc cagctgtttt ccaaaaaatg tctacgggtt atttaccaga
    18481 cttaagcgaa ggaagcagcc ttcacttctt gacattgatt ttaggaatga tcatcacgat
    18541 cgtgttagtt gttggtcaat ggcgaacaag aaatcgtcgg aaaaatcatt tatttgaagt
    18601 ggaatctcca acagctttct tggtaaaggc ggtatttaca gcagtcgttg tactaggaat
    18661 aacttatatc tttgcctctt atcaagggta tccgattatt ttgatcattc ttggtttgat
    18721 cgttgcagca tatgggtttt tgacaaataa aacagtagca ggtcgacaga tttatgcgac
    18781 gggcggaaat cgaaaagcgg ctgaactatc agggatcaaa acaaagcgaa tcacgttctg
    18841 ggtattcgtc aacatgggag tcatggcagc tttagctgga ttagttttag ctgctcgatt
    18901 gaatgcggca acacctcaag caggtacatc gatggaactg gatgcaatgg cggcagtata
    18961 ttttggtggt gcttcgactt ccggcggcat tggaacaatc atgggtgcga ttgtcggtgg
    19021 cttggtcatg ggtgtattga acaatggcat gtcgatttta ggcgtcgggg tagactggca
    19081 gcaggcaatc aaaggattga tcttgctttt agccgttgtg ctagacttgt ataataagaa
    19141 aaaacgaaca acgtaggaga acgccggtta ttcagaaaaa agactgtgac aagacatttg
    19201 tcacagtctt tttttcgcta aaagcgaaca ttcattgttt cgtttgtata gactaaaaat
    19261 aatatatgtt tttttaccat tcgtataaat tctctttttg ctcttgattt ttttgcttaa
    19321 ttgagttaaa ttacataggg cgctaaaaaa agccttgatt aaattaataa tgttcgtgtt
    19381 ttgctggatg tgaacatcag gaggataatg taatgaaagt atttgattac gaagatattc
    19441 aattaattcc taataaatgt atcgtaaata gccgttctga atgtgataca acggtcacat
    19501 taggtaaaca tacattcaaa atgccagtag tgcctgccaa catgcagacg attattgatg
    19561 aaacaatcgc agaattctta gcggaaaatg gttatttcta tatcatgcat cggtttgatg
    19621 aagcagctcg aattccgttt atcaaaaaaa tgaaaaagcg tggattgatt acctcgatca
    19681 gtgttggcgt caagaaagag gaatattcct ttatagagaa gttggcagaa gaatcgctaa
    19741 atcctgatta tatcactatc gacatcgcgc atggacatgc taactcagtt attgatatga
    19801 ttcagcatat taaaaaatat ttgcctgaaa cttttgtgat tgccggtaat gttggtacac
    19861 cggaagccgt ccgtgaattg gaaaatgcgg gcgcagatgc aacaaaagtc gggattggtc
    19921 caggaaaagt atgtattaca aaaatcaaga caggctttgg gactggaggc tggcaactgg
    19981 cagctcttag atggtgtgcg aaagcagctc gcaagccgat catcgctgac ggtgggatca
    20041 gaacacatgg cgatattgca aaatctgtcc gttttggtgc gacaatggtc atgattggtt
    20101 cattgtttgc cggtcacgag gaatctcctg gcgaaacaaa agtcgaaaat ggaatcgtgt
    20161 ataaagaata ctttggttct gcttcagaat tccaaaaagg cgaaaaacga aatgttgaag
    20221 gaaagaaaat ctggatccaa cacaaaggat ctttgaaaga tacactagtg gaaatgcaac
    20281 aagaccttca atcatctatt tcttatgctg gaggaagaga tctggaagcc attcgaaaag
    20341 ttgactatgt catcgtgaaa aattcgattt ttaatggaga cacaatctaa aaaataaata
    20401 aaatattagg atgttgtgaa aaagttgtcc tgcattaagt aataagaaca gccaaacaaa
    20461 aatagttctt tatatgtttt gtttggctgg aatt
//
LOCUS       DAZAOD010000049        19617 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000049 DAZAOD010000000
VERSION     DAZAOD010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.050"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(541..1566)
                     /locus_tag="ACHDPO_001705"
     CDS             complement(541..1566)
                     /locus_tag="ACHDPO_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3369326.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1841..3526
                     /locus_tag="ACHDPO_001706"
     CDS             1841..3526
                     /locus_tag="ACHDPO_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFN3369327.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3540..4823
                     /locus_tag="ACHDPO_001707"
     CDS             3540..4823
                     /locus_tag="ACHDPO_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369328.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4893..5762
                     /locus_tag="ACHDPO_001708"
     CDS             4893..5762
                     /locus_tag="ACHDPO_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369329.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5759..6595
                     /locus_tag="ACHDPO_001709"
     CDS             5759..6595
                     /locus_tag="ACHDPO_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369330.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6621..7688
                     /locus_tag="ACHDPO_001710"
     CDS             6621..7688
                     /locus_tag="ACHDPO_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFN3369331.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7685..8512
                     /locus_tag="ACHDPO_001711"
     CDS             7685..8512
                     /locus_tag="ACHDPO_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFN3369332.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8557..9582
                     /locus_tag="ACHDPO_001712"
     CDS             8557..9582
                     /locus_tag="ACHDPO_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFN3369333.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9579..11762
                     /locus_tag="ACHDPO_001713"
     CDS             9579..11762
                     /locus_tag="ACHDPO_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFN3369334.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11762..12892
                     /locus_tag="ACHDPO_001714"
     CDS             11762..12892
                     /locus_tag="ACHDPO_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFN3369335.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12889..13566
                     /gene="pgmB"
                     /locus_tag="ACHDPO_001715"
     CDS             12889..13566
                     /gene="pgmB"
                     /locus_tag="ACHDPO_001715"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFN3369336.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13650..14177
                     /gene="msrA"
                     /locus_tag="ACHDPO_001716"
     CDS             13650..14177
                     /gene="msrA"
                     /locus_tag="ACHDPO_001716"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFN3369337.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14378..15064)
                     /locus_tag="ACHDPO_001717"
     CDS             complement(14378..15064)
                     /locus_tag="ACHDPO_001717"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFN3369338.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15144..16682
                     /locus_tag="ACHDPO_001718"
     CDS             15144..16682
                     /locus_tag="ACHDPO_001718"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFN3369339.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16802..17269
                     /locus_tag="ACHDPO_001719"
     CDS             16802..17269
                     /locus_tag="ACHDPO_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFN3369340.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17803..18231
                     /gene="rplM"
                     /locus_tag="ACHDPO_001720"
     CDS             17803..18231
                     /gene="rplM"
                     /locus_tag="ACHDPO_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFN3369341.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            18247..18639
                     /gene="rpsI"
                     /locus_tag="ACHDPO_001721"
     CDS             18247..18639
                     /gene="rpsI"
                     /locus_tag="ACHDPO_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFN3369342.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(18727..>19617)
                     /locus_tag="ACHDPO_001722"
     CDS             complement(18727..>19617)
                     /locus_tag="ACHDPO_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3369343.1"
                     /translation="LPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMF
                     DIAEILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFN
                     NHLLTFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGR
                     KDTVIQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYL
                     NYRINSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNT
                     PDIVDKAVFEAFQRGLNKCD"
BASE COUNT         6354 a         3540 c         4157 g         5566 t
ORIGIN      
        1 gtctaaaata atttgtctaa ctagaagaaa agtgggaaag gatcttaaca acatcggttc
       61 gtatccaatt aaggtatcgg aacgatcatc ttccaagaga agtcaatcaa caaaagtaaa
      121 gatagatcat tttttgaatg caaaataaat tgatgggaag atagagcggt tatttttaat
      181 attttgctag ctattattga ataattcctc gaataaaaca aaaccagtag acatgtctgt
      241 tattctattt atgttttaga gataagtatc cccaaataac atggattgaa ataagggtaa
      301 atgtgtttaa aaaaacgaac tataaaaact tatacacaac gtggttaaaa atagtttttt
      361 cttccctgtg gaaaaaatag tttaacacaa acattatagt tatccacagc tatctaaaac
      421 agatggaaaa taagaaaaat tcgctaaaat accgggaggg ggtaacgagg gatgagtgat
      481 tgaaaaaaga acagagtaac tgacttatcc tcagtgtttc tgttctttta taattctgtt
      541 ctacatttct tgttgttgga tcgaatctgt gagagtaatc tcggttgaaa gaatgattct
      601 tttttcttca gggtattggt ggtggattag ttggaataaa agttctgtgg ctttgattcc
      661 taactgattt gtcggaatgt ctatccgagt caactgtggc gaaaataggg aggacaataa
      721 gggatcactg aatcctgcga tcgaaagatc atcaggtatc tgctttccag attgttctgc
      781 cactttgtaa atactcaatg attttaatgc atcggtagaa aaaatcgcag ttggtctttc
      841 tcgtagcttc attaaatcat tcattgctgc catgctatct tctaagcgaa agccgccgtc
      901 tataatccat tcattacgga tatctaggtg gtgatcaaat aagcattgac ggtaaccatt
      961 gagacgatca ttggatacat aaacttctgt cggagcatgg agacagccga tatgacggtg
     1021 tccattcttg atcagtgttt ccaccaaatc gtaactatcc tggaaattat ccgtgtccac
     1081 tgagtagatg ttcgtgtagt cgtttccgac ttttccgatt accacaatag gaatattgta
     1141 ttgatccaat tcaaaaagaa gtgtttcatc catcgtagag cttaaaataa taattcctcg
     1201 gatcattttt tcttggatct ttttcgcgca tttttctagc tcttcttctg gtgtttttgc
     1261 cgtttgtaga atcaagtcga agttattttg ttcagaaacg gcagaaatgg attgaataac
     1321 atctgaaaaa aaaggattgc cataggtcgt atgagaagta cgatgagata atgctagaat
     1381 cgcgtcaaaa ccatttcctg acagtcctct tgcaattttg ctcggttcat aattcaattc
     1441 tttgattgct tgaagtacac ttgcttttgc tttatcagag atatttggct ggttatttaa
     1501 tactctggag acagttgatt ttgagacatt agcttttttc gcaatgtcat aaatagtagg
     1561 tttcaatttt atatgcacct cctttttggg agcgttttag aataattcca tagtacaata
     1621 gacattcttt tttgtctatg attttgaaaa tttaggaata gcttgcatga tcatgagaga
     1681 ccatattttt ttaagaagct attaattatt gatacataag ctttcttatt tgtatttttg
     1741 tgtatatcaa aattatttaa aaaaatgcta ttgacagtaa gcgttttcca taatatgatc
     1801 aaatcgttgg gaacgctccc aaaaaagaaa ggggaatccg atgtatacaa aacttttaca
     1861 agcgatttat cgcgactcag atttgtctga gaaaaccgcc tctatgattg aacaaaaagt
     1921 cagtgtttat cagcagaaga aaggccaggc aggcaaactg cattgggacg aagaagatat
     1981 tttcttgatt acttatgggg atcaattttt tgaagagcag caaccaactt tgcgtacatt
     2041 taagaaattt tatcaaaagt atttggcaga tacatttaga gttgtacatt tcttgccatt
     2101 tttcccatat acatctgatg atggtttctc cgttgtaaat tatcaggcaa tcaacgaccg
     2161 tttgggcaca tgggaagata tagaagaaat gagaagcgaa acacggttaa tgttcgactt
     2221 tgtctgcaat catatgtctg ccgaaagtac ttggtttcag gaatatttaa acttgaatga
     2281 tacgtacaaa gattttttta ttgatttgcc actggataca gatacaagca gcgtgactag
     2341 accaaggacc agcccgttac ttacaacgtt cattgacaaa aacgggaaag aaaaacacgt
     2401 atggacgact tttagcgaag atcaagtaga cttgaatttt aaaaatccag aagttttatt
     2461 gaaaatgatc gatattcttt tgttttactt agaaaaaggc gcttcattta ttcgcttgga
     2521 cgctgtggga tttttatgga aagaactagg aacttcttgt atacacctgc cagaaacgca
     2581 taaaatcatc caattattcc gtgcaatcgc tgatgaagca gctccaggaa cggtattgat
     2641 cactgagaca aatgtgccac acaaagataa tatcagttat tttgggaatg gcgagaatga
     2701 agcacagatg gtctatcagt tttcgctacc acctttgacc cttcaagcga ttcgttcggg
     2761 taatacaagt aagttgaaag aatggttaaa aaccatcgat ttcgcatcga aaaaaacaac
     2821 tttttttaat tttttagcct cccatgacgg tatcggattg aatccggtac gaggtattct
     2881 gccggaaaaa acgatccttg aattagtgga acagctgaag aaagagggta cccgagtaaa
     2941 ctacaagaaa aacccagatg gaacgaccag tccatatgag ataaacgcta cgtatctaga
     3001 tgcgttaagt tctccaacag atacgacgga atggagaagc aaacgctttt tagctgctca
     3061 ttcatttttg gtaacgttac caggcgtgcc ggcaatttat attcaaagtg tgctgggaag
     3121 tcgaaatgat tacaaaggcg tagaaaaaac aggagagaat cgaaaaatca atcggcaaaa
     3181 atttttgtta gcagatattg agaaagagtt gcagacagat ccattaagaa cagcagtata
     3241 tggtgaattg acccagatgc tatctattcg aaaaaaagaa aaagccttcc atccgaatag
     3301 tttgatttac ttactggact cagcagattc ttttatcagt tttattcgcg aagcgaagga
     3361 agagaaagtc ttagttatcc ataatttttc caatcaatca gcaggttatc ttttaccaaa
     3421 aggagattac ctagacctgt tttctggaca aattatccat tgcagtcaag aacgaaagtt
     3481 gatattccag ccgtatgaat atatgtggct gaaaataata aaataagagg tggaaaaaaa
     3541 tgaaaaaaat tattgttact acctgtctgc tagctactgg atttcttctt actgcttgtg
     3601 gtgaaagtca aagctctaac gaatcacaac agacaacgat tcaattcatg cactcttctg
     3661 tcgaacagga acgattaagt gtgatcaatg aactggttgc tgattttgaa aaagaaaatc
     3721 cagacatcaa aatcaagcaa gtgccggtag aagaatcagc gttcaataca aaaatcgtta
     3781 cgttagctcg ttccggtaaa ttaccagaag taatggaagt cagtcaggat tttgctaaag
     3841 tgatggataa agatgaactg attgatcaga cggcagtcca aaacgttatc gaggaagctg
     3901 gagaagataa ttattatgac ggagccaaaa accttgttcg ttcagaagat ggaaaaagct
     3961 atattgctgc accaattagc ggctgggttc aaggtatttg gtatgacaaa gaaaaattat
     4021 cagaagctgg tttttcagaa ccagaaaatt gggatgatat tttaaaaatt gctcaacatt
     4081 tcacagataa agagaataaa caatatggaa ttgctatgcc tactgctgaa ggaacaatga
     4141 gtgagcaagc gttctctcaa tttgctttgt caaatggagc aaatgttttg gatgatgaag
     4201 gcgaggtaac gatcgatacg gaaaagatga gagaagcatt gtcgttttat caaaacttat
     4261 cccaatacac gatgccaggc tctaatgatg tgacagaaat caaagatgct ttcatgaatg
     4321 gaacagcacc aatggcaatc tattcaactt acattttgcc ttctgtttat gaagcgggga
     4381 actcagaaaa tatcggtttt gctatcccaa cacaaaaaga tcaagctgtc tatggcacag
     4441 tatctggatt gacgatttct tctggtctag acgagaaaca aaaagaggct gctgaagcat
     4501 tcacagcttt cttatctcaa ccgaaaaaca tggaaaagtg ggtcttgatg tctcctggtg
     4561 gtgctcaacc agtgaataaa caagtagtcg aactggatgg ttacaaagaa aatgaagtca
     4621 tcaagtcttt tggcgagctg ccatctgaga ttgctagtgc ttttgatgaa gtacaagtct
     4681 ttggactagt cggggaaaag aatttcacga aaatgggaga tatcacaagc tcaggtgtga
     4741 tcggaaaagc agtgaaccaa gtaactgtcg gaaacgaaga tgtcgatcaa gctttagctg
     4801 acgcacaaaa aaatacgaaa taacaagaag ttctgccaat ggtgttcgaa aaaagtagat
     4861 agctattggc agattatcag ggggaggttt caatgaatcg tccaaggaaa cattctgact
     4921 taaaattagc catgggactt ttagcaccaa gcatgctttt attagctgtt ttagtgctga
     4981 ttccaatgct ttccaatatt cagatcagtt ttttcgatat gccgctgaat cctaactcag
     5041 acgccgtttt tatcggatta agcaattatc ttgaaatttt aagtgatagt gaattttatc
     5101 gttctttagg tttaacagtt gcttacacat tcttagttgt agcaggcagt acagctttag
     5161 gattagccgt agctattttg cttaaccgca agttcagatt taggaaaacg gtgcgttcac
     5221 tgattttatt aagttatgtt acgccatcta tttctttgat ttttgcttgg aaatatatgt
     5281 tcaataatag ttatggaatc gtcaatgatc tgttagtaga taggttgcag cttttcaacg
     5341 aagcaccgct gtggttcgac cagccagttg ctagcttctt tatggtcgtt ttgtttgcta
     5401 tctggagata ctatccgtat gcgtttattt catttttggc tattttgcaa acagtcgaca
     5461 aaacgcttta tgaagcagct gaaatggacg gtgcaaatgc ttggcagaag ttcaagatcg
     5521 tgacactgcc ggcaatcaaa ccagtactag caactgtgat tgttttacga tctatctgga
     5581 tgttctatat gtttacagat gtctatctac tgacgaataa agtcaatatc ttaggcgttt
     5641 atttgtatca gacagccttt gcgttcaatg atcttggaaa agcagcagct atatcgattc
     5701 tattgttcat cattattgca gcggtcgtct tgctctcacg aaagaaggtg gacttgaaat
     5761 gaaaaataaa aagagcagga aaatcttatt ttacgcgacg attttgttgc tattagctgt
     5821 caatttgttt ccatttttga tcatgctgat gacatcattc aaggattcac aagaagcaat
     5881 tgcaacgaca caaactattt ttccgaaaga atggactttt gaacattatc aggatatttt
     5941 caatgctgag atttttccat tcatcatgta tttcaaaaat agtttagtga tctccttgat
     6001 agcctccgta actgcagtag tgattgggat cagcggggca tacgctttgt caaaactacg
     6061 cttcaaagct cgctcgaaaa tcaatgctag cttttacacc gtttatatgt tttccggtat
     6121 tttgatcgtt gttccattat ttaaaatcat ttccggtcta ggtttgtatg ataccaatac
     6181 agcactgatt atcacgatgg tcgttcaaac acttcctact gcgatattca tgctaaaaag
     6241 ttattttgac acgattccga ctgatattga agaagcagca atgatcgatg gtcttagccg
     6301 gatccagatc attattcgga tcattatacc attggctatt tctggaatca tttctgtctt
     6361 cgtttattgc tttatggttt cgtggaatga ttatttattt gcttcgattt tcctgtcgac
     6421 ctccgaaaaa tttactttac caatcggttt gaacacatta ttcagtacac cagactacat
     6481 ttggggacga atgatggccg cttcattggt gaccgcttta ccagtcatca ttatgtatgc
     6541 gttatctgaa cgatttatta aaggtgattt agtcgaaggc ggcgtaaaag gataaaaaga
     6601 aaagaaagag gaaagaaaag atgaaaaaat tagttgcatt agaaccaaga atagccggat
     6661 tcaaagatta cgaagaccgt gagatcgaaa agaacgaagt acgtatccga gtaattttcg
     6721 ctactccaaa accaggaaca gaaattgtcg actttagagg attaagtcca tttatcgatg
     6781 aagaattttc agaagaatgg cgcctattct tgccaagaga agaaggaagc caacgcggtg
     6841 tggtatttgg cgaatttcaa ttaggaaata tgattgtcgg tacgatcgaa gaaacgggca
     6901 gtttggtgac agagtatcaa aaaggagagt tagtctgcac ttatggaccc attcgtgaaa
     6961 cgctgattac aaacggtgtt gataattata aactacgtaa acttgatcgg ttggatcaat
     7021 ggaaaaatgc agtatgttac gatcctgctc aattcgcttt aggtggtatc cgggaagcac
     7081 atgttcgagc aggtgatgct gtagcaatct tcggtttagg cgctatcggg caaattgcga
     7141 ttcaattagc taaaaaagca ggtgctacta ccatcgttgg gatcgatccc atagcgcagc
     7201 gtagagaatt agcagaaaaa tacggtgccg attacacgct agatcctatg aaagcagatg
     7261 tcggttttcg tctaaaggaa ttgacagata aacgtggagt agattcagtt attgaaacga
     7321 gtggcagtgc tgccgcatta caagcttctt taagagggat cggctatggc gggatcattt
     7381 cttatgttgc ctttgctaaa ccttttccag ctgggtttaa tcttggtcgc gaagcacatt
     7441 tcaataatgc aaaaatcgtc tttgctcgag catctagtga accaaaccca gattacccaa
     7501 gatggaaccg taaacgaatc gaggacacat gttgggaatt attgatgaac ggttacttgg
     7561 attgtgaaga aatcattgat ccagttgtgc catttgcaga aagcgcagaa gcttacatgc
     7621 gttatgtaga ccagcaccca gaagaaagta tcaaaatggg cgttcaagtc cgaggaggag
     7681 aacaatgaaa ttcggtacgc aagatcaagc atttttccca agagacattt tagaaaaatt
     7741 tagatttatc aaagactgtg gatttgaaga atacgaaatc gacggtaagt tgttaataga
     7801 aaatatcgac acagtcaaac aggcaatcaa agaaacaggg atcccagtag tgacagcttg
     7861 taacggctac gatgggtgga tcggtgactt tatcgaagaa cggcgtctta atggtgtacg
     7921 tcaaattgct gagattttgc gtgcactaag cgaggttgga ggcaaaggaa tcgttatccc
     7981 agcagcttgg ggaatgttca cttatcgatt accgccgatg gtttcacccc gaagcaaaga
     8041 aggagactat aaagcagtca gcgaatcact tcgttattta gataaagtag ccgaagaaac
     8101 aggtacggtt atttatttgg agcctttgaa ccgataccaa gaccatatga tcaatttgtt
     8161 agcggatgcg cgtcattaca ttgactctaa tcaattgaaa catgtgcaga tcatcgctga
     8221 tttttatcat atgaatattg aagaagatga tatttcaaaa gcattgacta cgcaaaaaga
     8281 gtatgtgggt catatccatt tagcagataa tcatcgctac caaccaggat ctggcgcaat
     8341 tgattttact cgccattttc aaacgctact tcaaaatgag tatgaaggtt atatggtata
     8401 tgaatgtcgt ttgcgaggag aaaatgaagt gaaaatttat caggaatcat tgcaatactt
     8461 gaaaaactgt ctggaaacag cgcgtcattt aaatgattta gagaaagaat agagaaagaa
     8521 taacaataag taaataagca aaggagggag aaataaatga agaaagtagc aatcataggc
     8581 gctggacaag tagcagaaaa agtacatgct gcttattatc aaaaaagatc agatgtctta
     8641 gaattggccg ctgtggttga tccagtcagc cagcgagcag aagacttttg ccgacgtaca
     8701 ggattttctc atgcgtatac atcagttaca caaatgctga atgagatttc tcccgatatc
     8761 gtgagtgtct gtacacccaa tcgctttcac ttcgaacatg tattggctgc cctcgaagct
     8821 aatgcttcag tgatgtgcga gaaaccacca gctatgacag ctgatcaagc aagaaagatg
     8881 gcagagacag ccgataaaaa cgggcagatt ttggcttatg gattccagca tcgtttttct
     8941 gacgaagcaa caatgatcaa gaatcatctt gatgttctcg gggatattta ttacgtagaa
     9001 gcgaatgcgc ttcgtcggtc tggtgttcca ggctggggaa cgtttatcga caaagaactt
     9061 caaggaggcg ggcctttgat cgattatggc attcacatgc ttgatacagc gatgtatatt
     9121 actggatttc ctaaagtaaa aagcgttcgg gcgtacagct tccaaaaaat tggtacgaaa
     9181 aaaaattcag ggaaattcgg gaaatgggat ccaagcaaat tcacagtaga agatgcaatt
     9241 tttggcacac tggaattaga aaacggcaag atcatccaac tgaatacttc gtttgctttg
     9301 aatatcagag aagacaaact gaatgtggct ttttgtggcg atcaggcagg tgctaatctg
     9361 tatccaggcg aactattcga agatgtagat ggaaagctgg tttccttaca aaagaccacg
     9421 ccagttaatg acccacatga actaagtatg gctcattttg tgaatcgggc gctcggtgac
     9481 cagactcaga tgattgcaga tggctggcaa ggatatgtca tccagaatct ggtggaaaat
     9541 ttatatcgtt cggcagaaac aggagaagtt attaccttat gaaagtagaa gaaaaacagt
     9601 ttgatttaga gtatatcaat aagtatgcga gtcagatgac cattggaaat ggattttttg
     9661 gtatcagagg aagccaggag gaagactatc ggaatcaagt aaggggaatg tttgcagctg
     9721 gtgtatataa ccgaccttta ggagcagaat cagccgagtt agtgaatctc ccagatgtca
     9781 tcagatggga aataaaaatc gacggtgaac atttttctct tgagacgatg aaagttcttg
     9841 catacgagcg ggcactagat ttagaaatgg gagagcttaa acgctatgcg ctcattgaaa
     9901 ctgctcaagg aaaaaaagtg gaagtcatta cttgtcgtgt tgctgatcaa aataatctcc
     9961 atcaggcagc cctgaaagtg gtcatcaagc cgttgaccga agactgccaa gtagatgtga
    10021 aaacgggtat cgatggacag caaaccaatt ttggtacaca gcagttggtt gaaaaagaac
    10081 tgcgagtatt tggtgacgat ttgatcagtg catcctacca gacaacagaa agtaaaattg
    10141 atattgggat tgcagctaaa ttcaataaag caggtgtatt ccaagcaaaa aatcgccgga
    10201 tcaccgcttc cttttcagaa aagatcagaa aaaatacgtc ctttacgctg gagaagatca
    10261 tcgtgctctc tacctctctt cagcaaacag acccgtttaa gaaaagtatt gcccaagccc
    10321 agaaaagcgt tagttataca gaaattttag agcagtcgat gtcttattgg acagattttt
    10381 ggcatcagca tcggataacg atccaaggcg attcttcttt cgatcagtta gcgatggact
    10441 tcgctgctta ccatttacag attatgactc cccgcaatga tccaagtgtt agtgtagggg
    10501 cgaagggact aactggcgaa ggttataaag ggcatgtttt ctgggatacg gaaattttta
    10561 tcctgccttt ctttttatat cagtttcctg aagtagcaaa gaatttgctg ctgtaccgtt
    10621 atgatcgatt agaaggcgca cggcaaaaag caagagatta tcactatcaa ggtgcacttt
    10681 tcccatggga aagcgcacac actggtcagg aagagacacc caaatttgct gcattgaata
    10741 tcaaaaccgg aacaagacaa gaagttgctt cagctgccgc agaacatcat atcagtgcag
    10801 accttgctta tgccgttcaa gagtatgtcc aagcaacaga ggatcaatcg tttttagaaa
    10861 caaagggaaa aacgctcatt catgaaacag cagctttttg gctgagcaga gctgtaaaag
    10921 tcgatgatca tttagagata cacagagtca ttggtccaga tgaatacaca gaatatatcg
    10981 acaataatgc atatacgaac tatctggcgc attataatgt ggccttagct gttaaatatc
    11041 aagctggcga tccgcttttt ttgaaagaat gtcaaaattt tttagataag ttatatttgc
    11101 cagtgcctaa caaagaacag ctgattccgc aagatgacac gtatctcagt aagccagtta
    11161 ttgatttgac cacttacaaa gaacgtcctg gcagccagtc tattttactt gattatgccc
    11221 gtagcgaagt aaatgaactc caagtcagca agcaagcaga tcttgtcatg ctgttatact
    11281 tattacctga gtatttttct caaccaatcg tttctaagaa tttgcattac tatgaaaaca
    11341 aaacaatcca cgactcatcg ttgagtaaag cgattcacgc catagaggct tgccgtatcc
    11401 aagaaatgga atgggcgtat catttattcc aagaagcgtg cctgattgat ttaggaccag
    11461 atccgcattc atcagatgac ggaattcatg ctgcttcatt aggagcacta tggctagcag
    11521 ttatatttgg tttttcaggt attacagtaa cgaatggaac tctttctatt tctccaagac
    11581 ttccttcagc atgggaaaaa atttcttttc cttttatttg gaaaaatcac aggttgctat
    11641 ttgttttgac aaaaaaacaa atagtaataa aaaaagagac gaaagaaaca ttacctattt
    11701 ttgtcaatgg agaccaatac cagctggaaa aagaactgat cttggaacgg aggggaaaat
    11761 aatgcgtatt ctgattgcgc cagattcttt caaagaaagt ctgacagcct tagaggcagc
    11821 acaagccatt caatcaggtt ttcaagaagt ttttgttcag gctgaatatg atctgctacc
    11881 tataggcgat ggaggagaag gaacggtttc atcattagca gacagtttaa ggttgaagcg
    11941 gcaaacagca gtcgttacta atgcatttgg caaaaacaaa gaaatccagt acgcttcaga
    12001 cggtcaaact gcgatttttg aaatggcaga aatcgtcgga ttgaaagatg tcccactaaa
    12061 ccaacaacag ccacttaggt tatccacgcg aggagtagga gaactgatac gacaattgtt
    12121 gcaacaaggt gttcgacaca tcatcatcgg cgttggcgga agtagtacca acgatggcgg
    12181 catcggcatg gcagaaggtc taggttatgc tttttacgat caagataatc aaaaagtaga
    12241 agcactggga gaaaatctag gtaaaattgc tacagttgat aaaacgaacg tgcctattga
    12301 gctgattaaa gccaaaatca ctgtcattac tgatgttact aatcttttat gcggaaaaga
    12361 aggcgcttct tttgttttcg gaccacaaaa aggcttgaaa gaaaatgaat tagcagtggc
    12421 tgaccaagcc atgcatgatt tttatatgag atttgcccct caagtaatcg aggcatcggg
    12481 cagtagtgct ggtggtggaa tgggtgcagg actgttagca tttgcttcag ggaaaatagt
    12541 ctctggcatc gactacgtat tggatttact ggagttcgat aaacgggtac agcaagcaga
    12601 cctcgtaatc gtaggcgaag gacgtctaga tggacaaagt ctaaaaggaa aagcgccagt
    12661 tgggattgct agaagagtac cagagggcgt tcctgtgata gctatttgcg gaagtgttgg
    12721 taaaggaagc gaaaaagcag cagatgttgg catttcggcc gtttttccga tccttcctgc
    12781 agctgtgcct ttacaagaag ctttacagca agccactgat aatcttcatc gcacagctaa
    12841 aaacatcgca tctttacttc aagtcgttca ttttcaagga ggtaatcgat gaaaatcaaa
    12901 gcagcactat tcgatttaga tggcgttctt gtagacacag ctcgttatca ttacgaagcg
    12961 tggctggttt tagctaacca gctgtccatt ccattcactg agaaagaaaa cgagcaactg
    13021 aaaggaatat ccagaaccga gtcactagag cgattgctgt catttggaaa aatggaacag
    13081 aaattctcag aaaaagagaa atcagccttt gctgagcaaa aaaacaatct atatcttcaa
    13141 gcgattcaaa aaatggatga aacatccgtt ttgcctggtg caatagctgt tcttgagtac
    13201 ttgaaaaaaa caaacatcaa gatcggattg ggatcagcaa gcaaaaatgc acgcctcatt
    13261 ttagaaaaaa cgaatttgac aagttatttt gatgtcctta ttgacggcac gcaagtatca
    13321 aaagcaaaac ctgatccaga agtttttctc aaaggagcac agcaattgaa tgtaccgcca
    13381 aatgcatgct tggtcattga agattcagaa gctggttgtc aagcagcttt ggctggtaac
    13441 atgcatgtat tgggaatagg tgaaaacata aatcttcctt ctgctgaata tgtgattcct
    13501 gatttaaccg tttttgatca agtacgttcg ttttggcatt tatcagaagc cgtatcacgt
    13561 atataatagt ttccgttttt tctgtcacaa gcaaaacgtt atcctccttt tggaaatcaa
    13621 ggtatgatga gaaaaaaggg ggattttata tgacaaaaaa agcagttttc gcaggcggat
    13681 gcttttggtg tatggtcaaa ccatttgaag agcagccagg gatcatttct gtgacatccg
    13741 gttatactgg cgggcatgta ccaaatccaa cttatgaaca agtaacaaca ggcacaacag
    13801 ggcatacaga agcagtagag atcgaatatg atccagaagt tatttcttat gatcagttgg
    13861 tggaaatcta ttggcagcaa accgatccga ctgacgcatt aggacagttc gctgatcgcg
    13921 gtgattctta tcgtccagtg atctactata atgatgaaga agaacgaaat attgcagagc
    13981 gttcaaaaca agcattgcaa gacagcgggc gattcgataa gccaatcgtg acaaaaatcg
    14041 aaccaagaag cgaattttat cctgcagaag attaccatca ggattattac aagaaaaaca
    14101 agctccatta caatctttat cgagaaggtt ctggacgtgc aggtttcctt cgtcgacatt
    14161 ggggcgtcaa gaaataagaa gccgaaaaag ctacttatgg aacaccgtat atcagaggtt
    14221 gtaaaaccag cattttgagc taatactgag ggtcagctga ttgaacacca tttagtggag
    14281 aggttgtgaa cctgtcgcct agctccaagt cacaaggatt tggtaagaga acactatata
    14341 tcagaggttg tgacaagtcg tttgtcacaa ccttttttca atacctaaga tgaaggacaa
    14401 tcagcaacgc actgctcaaa aaaggaatga aaggcagctt ttccaacttt tttttatgac
    14461 agataaagta aacagaaaaa acggatattc caaacagact agcaagaaac aagatctgaa
    14521 gcaactcttc tagagacaag ccaccactcc aagaaagcat caacagagta tcgccagctc
    14581 cgagatagga ttgaccatag cgaaggcaca caccgcctac gataaacgtt aacagcacac
    14641 tttgccattg gaagacgccg gcctgcaacc aaaaaatcca taaaattgcc caagaacaga
    14701 atagcgtgtg agaatggacc atgaagtaaa ataaatccat caacgaaaat agcaaagccg
    14761 aaagcatcca tatgaacgtc gaaaaatttc ttgcggaaga aaaagtaaag aaccaggcaa
    14821 aaagaccacc acataaggct tctgccaaca aatagtagaa gggcaaccga cacctgcaat
    14881 agcggcagcg aaatcgttgg acgatgatcg agagaatcgg aatcaattca taccaagaaa
    14941 gcgaacgaca gcatttgaca caatgagatc taggataaat aatagagtga cctaacggaa
    15001 tccgctgggc ggttaaacat aaaaatgatc cgatacagca accaatgata aaataaagta
    15061 acacgccatc tccccctttt caaaaccaag atacgcaagc ttaaactaaa tttttgtaca
    15121 tacataaaat ttgaggtgaa aaaatgaacg tttcaatcgg attagatatc ggaaccacac
    15181 aaaccaaagc agttgctttc acagatgaag cccaagaagc agcatccgct tattttcgct
    15241 accctttgat ccaagaaaca caagggatgg cagaacaaga tcaggaattg atctttcaag
    15301 gtgtctgcac cgttataaaa gaagtaatta aacagttgcc ttcagacaca atcattcaat
    15361 ttgtctcctt ctcctctgcg atgcatggcc tgatattgtt ggatgaagag aaaacaccgt
    15421 tatctcgaat gatcacttgg gcagataacc gagcagcgga cgaagcagaa aaactgaaat
    15481 ataccgtgct tggcaaagaa ttttatcggc agactgggac gccgattcat ccaatgacac
    15541 cattgaacaa aatcaagtgg ctgcaaaaca gccaacctga attattcaaa aaaactgctt
    15601 attttgtcgg tatcaaagac tatatctttt atagattgtt tggcgaactg atcagcgact
    15661 acggaacagc ttcaggaact ggatattttg atatccatga attccaatgg gcagaagaag
    15721 tgcttgacta cttgaacatt cgaatagagc aattgccgca agtctttcct tccacctatc
    15781 aagtaacagg tctaccatca aaaacagcag cagaactagg tttgccaaat gatatatcat
    15841 ttgttttggg aggggcagac gggccgcttt ctaatctagg gttaggtgct tttggtgata
    15901 cgatcgccgc tttgaccgta ggaacgagcg gagcacttcg ttttattact actcagcctc
    15961 agttccatcc agaaatggag acgttttgtt atgttctgga tcagaaacat tgggtagtgg
    16021 gaggagcgac tagcaatggt gctggcatct ttgattgggc agggcataca tttttacagg
    16081 aagtcgttca atctgctaaa gaaaaaggag aaaatccata tgatgcactg ctttcggcta
    16141 tcgcttttgt gccagcgggt gccaatggtc tgatttttca tccctattta cttggtgagc
    16201 gagcaccgct ttgggacgca gatgcgtttg gcagttttat cggtttacag cggcaacata
    16261 cagaaaaaga aatgatgaag gcgattctag aagggatctg tctcaacctt tatcggattt
    16321 taaaaggagt ttgccaggaa aatcagctca cagagatccg tgctacaggc gggtttgctc
    16381 aatctccgat ttttcgtcag atgatggctg atgtactggg ttacccgctt gttttcccta
    16441 ctgtcacaga agcatccgca ttaggagctg tgattttagg ctggagaagc atcggaaaga
    16501 tccaaagtat cagtgaagca caggaattga tagaattgaa agagcaagtt ggagtacaag
    16561 aaactgatca taaaaaatat cagaaaatct atccattatt tgtttcgaca caaaagcatt
    16621 tagcacagac ttatcagcaa tttgctcaac tgcgagaaga attagctgat tctgaaaaat
    16681 gattggcttt acggataaaa aagcgaactg aaaatcgttc tcaggtaaat gattttgttg
    16741 tacttttcat tgaaagtcta ctattatttt aagtgtaaga aaatgttagg aggcaagaaa
    16801 gatgaaattc caacaaacca aagaagtatt aaatcaatta gttgcagatc taagccaaat
    16861 gtctgttgtt gttcaccaaa cacattggta catgagagga ccaggtttcc ttacattgca
    16921 cccaatgatg gatgagttca tggatgattt gaacgctcag ttagatgaag tatccgaacg
    16981 cttgatcaca ttagacggtt caccttattc tacattgcgt gaatttgcag ataacacaaa
    17041 aatccctgat gaaattggcc gctgggatcg tactattcca gaacgtttgg aaacacttgt
    17101 tgcaggctat cgttatctag cagatcttta ccaaaaagga atcgaagttt ctggagaaga
    17161 aggcgacgat ccaacacaag atatctttat cgaattcaaa acagccacag aaaaacgtat
    17221 ctggatgatc caagctcatt tgggcaaagc gccagagatc gacgcgtaaa aactgttgtt
    17281 gaacttgacc gaaaaagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa
    17341 acgtcaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat
    17401 tgaacaccgt ttaccaagag gttgtaagcc tgccgttcag ctccgagtca caagaaacaa
    17461 ttttaaaaaa cagcttctta tgttttatgg atattgtgac ttgtgaccga ggagttggca
    17521 ggagaacacc gtttattcaa aataaggggt tgtgacaaga cttttgtcac agcctctttt
    17581 tgtttttcat tttgacagga aacgaccctt ttatataaaa gaaagaaaag aagtaaagtt
    17641 tcatataaat ttttcaatca agcagaaaaa cgttgacatt gactagatta gcgggtaata
    17701 tgttaaatgg tattgtttgc cccacaaaga gccccggaaa ctcgaagtgt atgtcaaaca
    17761 tcagaactta aattggagga aaataacgtg cgtacaacat atatggccaa accaggcgaa
    17821 gtagaacgta aatggtatgt agtagacgca actgatgttc cattgggacg tctttcaaca
    17881 gttgttgcat ctgtactacg tggtaaaaat aaaccaactt tcacacctca tttggatact
    17941 ggcgatttcg tcatcgtcat caatgcagac aaagtgaaat taacaggtaa aaaagcgact
    18001 gacaaaattt attaccgtca cagcaactac ccaggaggat tgaaatcaat cactgctggc
    18061 gaattgcgtg ctaaaaattc tcgtcgtttg atcgaaactt ctgtaaaagg tatgcttcct
    18121 aaaaacactt taggccgcaa acaatttaca aaattgaacg tatacggtgg agcagaacat
    18181 ccacatgcag cacaacaacc agaagtttta gacatcacaa acttaatcta ataggaggga
    18241 atttcattgg cacaagttca atatatcggc acaggccgtc gtaaaaacgc agttgctcgc
    18301 gtacgtctag taccaggaac tggcaaaatt actgtaaata aaaaagatgt tgaagaatac
    18361 attccacatg ctgacttgcg tgaagtaatc aatcaacctt tcgctgttac tgaaacaaaa
    18421 ggcgcatatg acgtatttgt taacgtaaac ggcggaggat acgctggaca atcaggagct
    18481 atccgtcatg gtatcgctcg tgcattgcta gaagttgatc ctgacttccg tttagctctt
    18541 aaacgtgctg gcttacttac tcgtgacgca cgtatggtcg aacgtaaaaa accaggtctt
    18601 aagaaagcac gtaaagcttc acaattctca aaacgttaat atcctttata tatcaacgtt
    18661 tctggcactt ttcaattatt tggaaagtgc ttcttttgtt tttaagaaca catttaagaa
    18721 cacatatcaa tcacacttat tcaatcctct ctgaaaagct tcaaaaacag ccttatcaac
    18781 tatatctggt gtgttcacat atatctttgt tgtagaaata tctgagtgtg ttaaagcatt
    18841 tgaaatttga ttcatatctg ctccaccttg tctagctata gttgcataag tatgacggag
    18901 tttgtgtgga gataaatgaa ctaagtcagg atgccttctt ttaattgaat tgattcgata
    18961 gtttaggtaa tcggcatgaa caggacaatt tacttctcca gatggtttag tataagtaaa
    19021 gagatactga tctaacgttt gcttaatttt taatttcaac aattgatcag cttgtaccga
    19081 tttccattca cttagcaatg tcattacaac ttctggtact tgaatgacgg tatcttttcg
    19141 accttttgta aacttttttc tttgatattt atctaaagta tgtttaagac ggaccgtttg
    19201 tttttcaaaa tcaatatatt tccattgcaa agcgtaagtc tcactttttc tatcaccaag
    19261 atacagggta atcataaaaa gtgtgtaatc atgaaaagta agtaaatgat tattaaaatc
    19321 atcatttact gcttctatcc aattagtaag ttcttttgat gatagtgctt gcttaccttc
    19381 ttgtattctt ttttcttcta aagcattttt tttaggtgca gtgatacttt gaataatttt
    19441 agtagttcga ttaaattcga tataatttag tatttctgca atatcgaaca tggaacgaac
    19501 atatcctttt atgattttta tatttgcata ttctttcgat tttttggtta attcatctga
    19561 tattatctca gtattgatat ttagataatt cattgcgtat tcaccaaaca taggtaa
//
LOCUS       DAZAOD010000050        19206 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000050 DAZAOD010000000
VERSION     DAZAOD010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.051"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..429)
                     /locus_tag="ACHDPO_001723"
     CDS             complement(<1..429)
                     /locus_tag="ACHDPO_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369344.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDE"
     gene            696..2396
                     /locus_tag="ACHDPO_001724"
     CDS             696..2396
                     /locus_tag="ACHDPO_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFN3369345.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGRGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            2366..2584
                     /locus_tag="ACHDPO_001725"
     CDS             2366..2584
                     /locus_tag="ACHDPO_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFN3369346.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            2604..3494
                     /locus_tag="ACHDPO_001726"
     CDS             2604..3494
                     /locus_tag="ACHDPO_001726"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFN3369347.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            3512..3796
                     /locus_tag="ACHDPO_001727"
     CDS             3512..3796
                     /locus_tag="ACHDPO_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369348.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            4283..4897
                     /gene="gmk"
                     /locus_tag="ACHDPO_001728"
     CDS             4283..4897
                     /gene="gmk"
                     /locus_tag="ACHDPO_001728"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFN3369349.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            4902..5207
                     /gene="rpoZ"
                     /locus_tag="ACHDPO_001729"
     CDS             4902..5207
                     /gene="rpoZ"
                     /locus_tag="ACHDPO_001729"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFN3369350.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            5460..7868
                     /gene="priA"
                     /locus_tag="ACHDPO_001730"
     CDS             5460..7868
                     /gene="priA"
                     /locus_tag="ACHDPO_001730"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFN3369351.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            7883..8374
                     /gene="def"
                     /locus_tag="ACHDPO_001731"
     CDS             7883..8374
                     /gene="def"
                     /locus_tag="ACHDPO_001731"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFN3369352.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            8367..9305
                     /gene="fmt"
                     /locus_tag="ACHDPO_001732"
     CDS             8367..9305
                     /gene="fmt"
                     /locus_tag="ACHDPO_001732"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFN3369353.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            9305..10663
                     /gene="rsmB"
                     /locus_tag="ACHDPO_001733"
     CDS             9305..10663
                     /gene="rsmB"
                     /locus_tag="ACHDPO_001733"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFN3369354.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            10676..11416
                     /locus_tag="ACHDPO_001734"
     CDS             10676..11416
                     /locus_tag="ACHDPO_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFN3369355.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            11413..13482
                     /gene="pknB"
                     /locus_tag="ACHDPO_001735"
     CDS             11413..13482
                     /gene="pknB"
                     /locus_tag="ACHDPO_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFN3369356.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            13647..14546
                     /gene="rsgA"
                     /locus_tag="ACHDPO_001736"
     CDS             13647..14546
                     /gene="rsgA"
                     /locus_tag="ACHDPO_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFN3369357.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            14559..15209
                     /gene="rpe"
                     /locus_tag="ACHDPO_001737"
     CDS             14559..15209
                     /gene="rpe"
                     /locus_tag="ACHDPO_001737"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFN3369358.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            15210..15848
                     /locus_tag="ACHDPO_001738"
     CDS             15210..15848
                     /locus_tag="ACHDPO_001738"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFN3369359.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            16003..16857
                     /gene="mreC"
                     /locus_tag="ACHDPO_001739"
     CDS             16003..16857
                     /gene="mreC"
                     /locus_tag="ACHDPO_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFN3369360.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            16861..17370
                     /gene="mreD"
                     /locus_tag="ACHDPO_001740"
     CDS             16861..17370
                     /gene="mreD"
                     /locus_tag="ACHDPO_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFN3369361.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            17625..19199
                     /locus_tag="ACHDPO_001741"
     CDS             17625..19199
                     /locus_tag="ACHDPO_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFN3369362.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT         6501 a         3515 c         4119 g         5071 t
ORIGIN      
        1 ttcatctaaa tagcgataat aaatccgatt cagctgatca ttaagatcga agtatacaaa
       61 attattctgt agtttataaa aaaacggcga atgaagatgt gttttcatat gaccaaaata
      121 taataattct gaaatttcta aaggtgtcaa ttctttcagc atcgttaaat cagtaaagtc
      181 gatccacttc aattcatcga atccacgcct gttacgagaa gaggaaaaga aacgctgaat
      241 attttctgta ccacggatta ctttcagccc tgtatgggat tcatattctc cagcagaagc
      301 agatggatca agcaagagca agttttgagg aaaatgcacg atactgtttg caaagtcagt
      361 agcagtcagc ccttttgtta aaacagcatt acttgtggta tcaatatgta cataaactga
      421 ctcagtcatc atgttcctcc tcttatttcc tcttaatctc ttttatttta caacatttgc
      481 attaaaaaag cttgtttctt ttattttaaa attccattac aaaatcacgt tttcattgaa
      541 aacactctca ttttcaatta atttttgtga tttttgtatt tttttattta aaggaggttt
      601 tatgaattgt tttcttatgg aatctacaaa gtcgaatacg agactcatga cctttttatg
      661 acgtactggt atacttgaag aaaaaggaga gcgcgatgga gataaaaaaa gtttactttt
      721 cacagaaaat gtcgctgtat tcgcctatcc agcaagcaaa acaacccctt ccattttttc
      781 aaagtcatca agaaagtaga gacgcttttt ggcgttctgc aaaaaagcaa tgtgctttta
      841 aagcagtatc gaaaaaatat accgtctatt ttactattgc taaaagtaga ggagatgtta
      901 tttttaataa tctgttgatt gaaggtgaaa cttttgaatg gaaaaaattt tttcggtata
      961 tggaagcttg cgctcgtttt tttattaaag aaaactgttg ttttttattt caatctcctc
     1021 tatcagaaga atggttgcgt atttttcata aaaacggcta tcaaggaacc acacaattaa
     1081 ataaaaagct ggtctatcat acagcacttg ttttaggtag aggaggagcg cacggtgctt
     1141 atcagattgg tgtgtggcag gcgctgaagg aacatgatat caactttgag attatcacag
     1201 gtacctcggt aggtgcgttg aacggcgcat tgattttaca aggagatatg aaaaaagctg
     1261 tgaatttatg gaaaaagctg tcgacaagac aagtgcttgc gttaccagaa atggctgcag
     1321 ttgaagacct tcgtgaacgc ttctatcgag aaagacgcca aatgacgaaa acagcactaa
     1381 ttgaaggcgg ggtttcttct gctccattgg aaaagatggt caaagacaat ttggatttgt
     1441 ccttactcaa acataatccc aaaatacgtt tatatacggt gtctactaaa ctgccagaac
     1501 tagcggaagt agtgactgat atccaacaga caaaaacaga agaaatacca gattggatac
     1561 tcgcctctgc ttcattttat cccgctatgg cttatcgaaa gatcggaaaa aataaatatg
     1621 cagacggtgg gtatcgcaac aaaataccta ttgatattgc gattaacaaa ggagcaacag
     1681 aggcatttgt cgtagatgtg caagggccag gcccagcgaa aaaaattcgt atgccagaca
     1741 tttttatcca ttggaaatgt caaacattgt ggacactagg cagctttctg ctttttgata
     1801 gccaaaggaa ccaattaaat ttacaattag gctatctgga aatgaaaaaa cgattaggct
     1861 attactatgg gaactggtat acatttcatt ctgttaaacc tgcaagaaca tactggcgag
     1921 gatttttgtc ttacttaaca aaagaaattc agttagaatt atcttttttc aaaagcataa
     1981 aattttggca aaaactgcgt aatttatata agaacagggt cgtaccagag acatgcggat
     2041 tggcgatgct agaactttta gcaaaaaaac attttttact gcccaatgaa atctatcaag
     2101 tagacatgat gattcaaatg atctgccaac aagatataaa aagtatgccg gatgatttat
     2161 tggcacaaat tggtcaatta agtactgaag aatggcgaag gtatcgaaaa taccagcaaa
     2221 aaatacaaaa tgagcgcacg aaaactgttt attttgatta tctgctacaa ggaaaacgca
     2281 aggatcgttt gcagcatgaa ttgcttaagc aaccagttga cacattactg atcctatatt
     2341 tatattatct caaggaggaa caaccatggc acaagaattt tcatatgaaa tcgtagaaga
     2401 aatcgctata ttgtcagaaa acaacaaggg gtggcgtaaa gaactgaacc tagtcagctg
     2461 gaatggtcgc ccgccaaaat tcgatcttcg agattgggcg ccagaccatg aaaaaatggg
     2521 gaaaggcctg acattgacga acgaagagtt tgaacaactg caaaaagcaa tagaaaatat
     2581 gtaatgagga aggaccctgt cgaatgaaaa gtatgactgg ttttggcaaa gccatccgcg
     2641 aaacaaaagc gtatcagtta gatattgaaa taaaaagtgt caaccagcgt tttctagatg
     2701 ttcaaatacg aagtcctaaa atcctgaact ttgttgaaaa cgattttcgt cagcttatta
     2761 aacagcagtt aagccgcggt cgaatcgaag tatttgtgaa tctagcttat attggcaaaa
     2821 acgaaaaaca gatcgtcatc aactgggaat tgattgattc acttatcact caattgacag
     2881 acggaattca acaacgatac ggtagtcaaa atcaagtgtc aattagtcgg atggcggaac
     2941 gcttcgtgct ggacgaaaac ttcgtaacgg tagaagaaaa accggaagag agcatggaag
     3001 aattggcaca gttagctcta gatacattga aaagcgcact tgattctatt gaggcgagtc
     3061 gagaaaaaga aggtcaagct ttagctttag tgttgaaaaa gaatactgaa gaattcaaag
     3121 aagtactaaa aaaactcgat agttttgtag aaatctatga aaaggaattt caaataaggt
     3181 atcaaaaaaa gctggaggaa tttcttggag cgaaagtcga tgagcaacgg ttgttgacgg
     3241 agctagccat cttgttggaa cgcggagata ttcacgagga actggatcgt ctggcgatcc
     3301 atgtacaaaa actagatgaa cttatcgaag cacaatgtcc tgtaggtcgg gaattagatt
     3361 tcctgatcca agaaatgaat cgggaaatca acacgatcgg ttccaaatca aatgcaatcg
     3421 aaattaaaaa tcaagtcgtc cagtctaaga cgatcttaga aaaaatcaga gaacaagtac
     3481 aaaatattga atgacgaaag aggtagagat aatgaaatat tatgacgtaa cgttccacga
     3541 attaagtgga aaaactgtgg ttaaacggga tatcccttct gaaaaaaacg gctttgacgt
     3601 atggaaagat gcctgtgcag actataatga gaacgaactg tttattttga tcaacgacgg
     3661 tgcttacgtg acgatgaatc ggaaatttat tgttcgaatt gacacagaag aggtagaaga
     3721 tccgacagaa aaagcacgtt ctcgaaaaga tgagatcatg ggtgtagtga atactttgtc
     3781 caatatgggc ttttagcaag gatgctgaac aaagaaatac aataaataaa cagaattgga
     3841 tttcttcgct tagcttcttt gctctaggaa tacatttaaa ggttgtgaca aaattcgtgt
     3901 cacaatcttt ttttattttg aataagtgat gttcaaaaac cattttctcg gtattaagcc
     3961 aaatttatgc aaaaatgtga gaaactattt tcacaaaatt tttcttcata ctcgaaacta
     4021 atcggcttct tcacgacctc ttatacacgg cgttcaaaag cttgcatctg cgataataac
     4081 cccaaccaaa cgaaaaacat gagaagctgt ttatgtttgg ctgttcttat tacttgatgc
     4141 aggacagctt ttttacgacc tcttggtaca gggtagcttt tttaccaatt tctagctata
     4201 attaaagata accttgaaag ttgcagaaaa aaagtgcaaa ataaacgata agtacaaaaa
     4261 gactagttga aaggacgtcg tcatgtcaga gcgtggatta ttaatcgtgt tgtctggtcc
     4321 atccggtgta ggaaaaggca cagtacgaaa agcaattttt gagagtgagg ataatgattt
     4381 tcagtattcg atctcaatga ctacccgtaa aatgcgtgaa ggggaggtcg aaggcgttga
     4441 ttatttcttc cgaagcaaag aagagtttga atcaatgatc gaagctggag agatgctgga
     4501 atacgcagaa tatgtcggga attattatgg aactcctttg tcatatgtca acaagacatt
     4561 ggatgaagga aaagatgttt tcttggagat tgaagtccaa ggagcaaaac aagtcaaaga
     4621 aaaagtgccc gatggtgtat tcatcttttt gactccgcca gatttagcgg aattaaaatc
     4681 acggatcgta ggccgaggaa cagatgcaga tgaagtaatc gaaaaacgaa tgaaagttgc
     4741 aaaagaagaa atcgaaatga tggctcttta cgactatgct gttgtaaatg atgaagtgcc
     4801 gctagcagtt gaacgaatca aaaacattat tgccagtgaa cattttcgag tagatcgcgt
     4861 aatcggtaaa tatattaaaa tgttaaagga gatgtagtct tatgatgtta aaaccttcaa
     4921 ttgactcact attagatcgt gtaaattcaa aatattctct agtgatttta gcaagtaaac
     4981 gcgcgcatga attggatgca agtgcacagc ctactctaga ttcttttgat tcagtaaaaa
     5041 gcgtcggtca agctttagaa gaaatcgatg caggaaatgt agtcaatgat ccacatcctg
     5101 aattaaaacg tgaacgtttg aagatggaag aagaggaacg tcaagcacaa aaagagcgtg
     5161 aacaacacga attggaatca cgtatccgtg aagagcaaaa aatgtaataa agaaaaatag
     5221 agcgaacatc taaaaagaaa agcaaaccca gctgtttcct tttcaaacat tcgccactta
     5281 ttgtctggta gaaaaggctg tgtctgaact ttttgacaca gttctttttt ttcttatctg
     5341 ctgttaattt tttgttagga tttggcagaa gataagacaa atccatcgat ctctagtaaa
     5401 ataggcaagg aactttttgt cgcttgataa gaaaagacaa aaaaaggagg aaacgaacca
     5461 tgacattaac agctgaagtc attgtggacg tacctactat gcagaccgat cagccattca
     5521 cttatttggt tccctctgaa atggaaacag ctttgcaagt cgggatgcga gtagaagtcc
     5581 cttttggtaa tggcaatcgt catgtccaag gatttgttat ggctatccaa aaatcagaag
     5641 aatcagctaa tccatctttg aaggcagtta ttcgtttgct agaccttgct ccggtggtca
     5701 atgaagaatt actttcatta gctgattata tgaaaaaaat tacttacgca ttcaaaatca
     5761 cttgtctaca aacgatgctt ccgagtgtga tgaaagcaga atatgataaa ttgatctatc
     5821 ctttggcaga cacaccagaa gttcaggtat tgtttgatca gcgagaagtg atttcctgga
     5881 aggaagcaga agaagaaggc agcctttctc aattgattcg ctggcgccaa gagcaattag
     5941 tagatatcaa atatgaagtc catacacgaa ataaagtaaa aacgattcgt ttggtccgtt
     6001 ctttgttaac tgaaaagcaa atcgaagaag aatgggcaaa attacggcaa aatgccaaga
     6061 aacaaaaaga acttcttttg tgtttatctg aactgagcca agaagaacca attgcttatt
     6121 tcaaaaataa aggaatcagt actgctgtct tgaatcaagg aaaagaaaag ggctggctgg
     6181 agtttataga atcagaacgt tatcgcgacc cttataaaga ccgagtattt gaccaaacga
     6241 cggcattgga actgaatgca gaacaaaaaa atgctgtcga acaaatcatc acagcaggtc
     6301 agcagcaaaa agatcaggtc tttttgctgg agggaatcac tggcagcggg aaaacagaag
     6361 tatatcttca ggcaatcgct gatgttttgt cagaaaataa aacggctatt atgttagtgc
     6421 ctgaaatcgc attgactccg caaatggtcg agcgattcaa aggacgcttc ggagaatcag
     6481 ttgcggtctt acatagcgga ctttcccaag gtgaaaaata tgatgaatgg cgcaagattg
     6541 agcgggaaga agcgcaagta gtagtaggcg cacgatctgc tatttttgcc ccgctgaaaa
     6601 atatcgggct gatcattatc gatgaagaac atgaatcaag ttacaaacaa gatgagacac
     6661 cgcgttatca tgcgagagat ctagcaattt ggcgcagtaa atatcatcat tgcccaatag
     6721 ttctaggaag cgcgacgccc tctttagaat caagagcacg agctcaaaaa ggcgtttatc
     6781 agttattgca gttaaaccac cgagccaaag cagctgcaca gcttccagct attgagatcg
     6841 tagatatgcg tgaagagttt cagaatcatc ggacctctac tttttctgct aatttgcagg
     6901 aaaaaataca aaatcgatta gacaaaaaag aacaaactgt cctactgctc aatcgtcgag
     6961 gatattcgtc ttttgtgatg tgtagggact gtggatttgt tcttccatgt cctaattgcg
     7021 atatctctct tacactgcat atggatacac gttcaatgcg ctgccattat tgcggacatg
     7081 aagaacctat tcccaatcgc tgtcctaatt gtggcggcaa taaaatccgc tactatggaa
     7141 caggtactca aaaagtagaa gaggaactcc gagaacttta tccgcaagct aggattttgc
     7201 gtatggatgt agataccact cgaagaaaag gggcacacga acagatttta caaaaattcg
     7261 gtgcaaaaga agcagatata ttattaggga cacaaatgat tgctaaaggt ttggactttc
     7321 cagaagtgac attagttggg gtgttgaatg ctgatacctc cctgaattta ccggattttc
     7381 gttctagtga gcatacattc caattgctta cccaagtttc aggacgagca gggcgagcgg
     7441 aaaaagcagg cgaagtcgtg atccaaacat tcaatcctca acattacgcc atagaattgg
     7501 ctaaaaaaca aaattatgag cagttttatc agcaggaaat gcatgtacgg catcgtggag
     7561 gctatcctcc ttattacttt actgtgaaaa taaccgccag ccatcctgaa gaacaagtag
     7621 cggcaaagaa aatctttcag attgccaatc agctaaaaga agtgttaagc cctcaaagct
     7681 tgctattagg gccaacgccc agcatgattt tgagagtgaa aaaccgatat tattatcaac
     7741 taatcatcaa atataaacat gaaccgaatc ttcctcatgt tttggatgaa attttgaatg
     7801 gaagccagaa agaacagcga caaggtcttt ttgtggcaat tgacaacgaa ccattaaact
     7861 ttatttaaga aagggccaaa ttatgcgcta tcctatattg atccacccta atgataaatt
     7921 aaaaagaact gctcagccaa tcgatgtaat cacggacgag acaatcgctt tattagacaa
     7981 tttatatgag acaatgattg cgaatgacgg aatagggatc gctgctcctc aagtaggaca
     8041 aaacaagaga attgctgtga tcgaagtaga tgaaggcgag aaatttgaac tgattaaccc
     8101 agaaatcatc gaagcaaaag gtgaaagcct tgacgtagaa ggttgtctca gtattccgca
     8161 tgtctatgga acggtcaagc gagcagatga agtgaccgtg cgttattatg atcgagacgg
     8221 agaagagata gaagtgacgg cttttggcta tttagcccgt gccttccagc atgaaatcga
     8281 tcacttagac ggtatcttgt tcattgagaa aatgatacag cagatcccgg aagaagaact
     8341 tgaagaatat atggaggaac atcttgatga ctaagctagt atttatgggc acacctgctt
     8401 tttctgtgcc gattcttgaa gggctgatag aatcaggtta cgagatccag gcagtggtaa
     8461 cacagcccga ccgtccagtt gggcggaaac gagtaattac gccgacaccg gtaaaaaaag
     8521 cggctctgaa gcacggtatc cgtgtgctgc agccagagaa aatctccggt tcgccagaaa
     8581 tggaagaaat cattgaattg gtgcctgatg tgatcgtcac tgcggcattt ggccaattct
     8641 tgcctgaaaa gttattgcaa gtaccaaaat taggggcaat caatgtccat gcttctttac
     8701 ttcctaaata tcggggaggt gcgcctgttc attatgccat catgaatggg gagaaagaaa
     8761 ctggtgtaac gatcatggaa atgatcaaaa aaatggatgc aggcggaatc tatgcgcaag
     8821 aaagcatacc aatcactaaa caagatgatg tagggacgat gtttgaaaag cttagccttt
     8881 taggaagaaa gctattgcta gaaacattgc ccaatatttt ggatggacaa aaaccagtac
     8941 ctcaagacga gtcagaagca actttttcgc caaacatcac acgggaacaa gaagcaatcg
     9001 attggcataa aactgcagaa gaaattgaca accaagtacg cggaatgcgt ccttggccaa
     9061 ttgcattcac gacctatgag ggcatacgct ggaaattatt atcggttgaa gtattggcag
     9121 aaactacaga caaagcacct ggtacgatca tccggaaaga caaaaaaaat ctatggattg
     9181 cttgcggtaa acagaccgtc ttagccatca atgaattaca gccagctggt aaaggaaaac
     9241 aggccgtaca tgatttcctt aacggaagcg gtcagcaagt tcagattggt cagcaggtga
     9301 aataatgaaa aaaatcccta aaaaaatgaa aaaatcagta cgatatatgg cattactgac
     9361 attagagcga gtgaacaagg gtggcgccta ctcgaatctt ttgttgaatg agatgatcaa
     9421 acaaagcgag ctaaatcaaa aagatgtggg tttatttaca gaattgatct atggtacgat
     9481 tagccatcag cgactattgg aattttacgt tgcaccattg atcgctaaag caaaaaaagt
     9541 ggatgactgg gtcaagatgc ttctttatct ttctgtatac caattagaat ttttagataa
     9601 agtccctgca catgctattt taaacgaggc ggtcgaaatc gcaaaagtaa aaggaaatcc
     9661 tgggacaggg aaatttgtaa atggtgtctt gaggaattat cagcgtcaag gagcaccaga
     9721 tctgcaaggc attgctgatc ctatcgaaag actttctgtc aaaatcagcc tgcctctatg
     9781 gatgacgaaa cgactggtgg atcaaatcgg atacgaagaa actgaaaagc tcggtttatc
     9841 gctatatcag cctagccatg ctagtgcccg agtagataca cgccgacttt ccagagatca
     9901 ggccatcact gttttgcaag aagaagagat cacagctgaa aaaagccaag tcagtccata
     9961 cggtatagta gcgaaaaaag ggcatttagc ttctagctca ttgttccacg atggcgtcat
    10021 gacgatccaa gatgaaagtt cgatgcttgt agcgccgtct atgcaaatcg agcctgaaca
    10081 tcatgtctta gatgcctgtg cagcacccgg aggtaagacg acgcatattg cttctttttt
    10141 agatccgtca tgcggtggag aagtggtcgc tttagatgta cacgaacaca aagtcaaact
    10201 cattgaagat aatgcagcac gtctaggtgt ctcttctgct gtctacgctc aaaagatgga
    10261 tgctagagaa gtcagtaaac agttcgaagc agagcagttt gatcggattt tagtagacgc
    10321 gccttgttca ggtcttgggc tgcttcggcg aaaaccagat attcgttata aaaaacagcc
    10381 ggatgaatta gcgaatttac caaaaatcca attggaaatt ttagaaagct gcgcaccaac
    10441 tttaaagtct tccggtattc tgacttatag cacttgtacg atcttaaaag aagaaaacca
    10501 agacgttgtt tctgctttct tggaaagaca ccctgatttt gagaggattg atgttttgac
    10561 caatcctatg ctacaatcat caatcgaaga gaaaatgttg actttgtatc cgcatcagtt
    10621 ttacacagat ggatttttca tttgttgttt gcgcaaaaag taatgaggtg aaaaaatgca
    10681 gattgaatat caatcagatg taggaagacg acgtaacaca aatcaagact atgccagtgt
    10741 atttaccagc cgttcaggtc tcaagcttgc tgtattagca gacgggatgg gtggtcatcg
    10801 tgccggagac attgccagtc agatggcggt aacgaatcta ggcgaagctt gggaaaaaca
    10861 agaagctgtt gacgatgaaa aaatcgccca atggttcatt caatcgattc aagaagaaaa
    10921 tatgctgatt tatcagcgtg gacaagaaca gccggaatat aacggtatgg gaacaacaat
    10981 cgtagcggcc gctctgtcag atgactggtt cacgattgcc aatgttgggg atagcagagc
    11041 ttatttgatt cgtgaagata aaatcatgca attgacggag gatcattctt tagtcaatga
    11101 actagtcaaa tcaggagaaa tcagcgaaga aatggcagtg aaccatccaa ggaaaaatat
    11161 tttaacacgt tctgtcggca tgcctggaac agtcgaagta gatgtttcta ctcatctttg
    11221 gcaactaaaa gatcgactgc tgttatgttc agatggcttg acgaacatgc tgtctgaaga
    11281 agaaatagga acgatcatca atcaagaagg cccattgtct cataaagtaa ctgagctgat
    11341 tgatcgtgcc aatgaagcag gcggagcgga taatatcacc gttcttctta tcgaatataa
    11401 ggaggacagt gtatgatcga gttgggcaaa aaattaaatg gccgttatca aatcactgga
    11461 aatatcggta gcggtggtat ggcaaatgta tttttggcgc acgatttaat cttggatcgt
    11521 gatgtagcag ttaaagtctt acgatttgac tttcaaaatg accagactgc gattcgacga
    11581 tttcagagag aagctttagc agcaacagaa ctcgttcatc caaacattgt tagtgtttac
    11641 gatgttggtg aagaagacaa catgcagtat ctggtgatgg aatacgtcaa aggaatggac
    11701 ttgaaacgat atatccaaac acattatcct gttccttatg aaacagcagt aaatattatg
    11761 cagcagatcc tttctgctat ttctttagct cataaccatc aaatcatcca ccgagatttg
    11821 aaaccccaaa acgtactgat cgataatgaa ggtgttgtaa aaatcacgga tttcgggatt
    11881 gctatcgctt tatctgaaac atcgatcacg cagacgaata cgatgctagg atctgttcat
    11941 tatctgtccc ctgagcaggc cagaggaagt atggcaacga agcagtcaga tatttatgct
    12001 ttagggatca tcctttatga gatgttgacg ggtagcgtac cgtttgatgg tgaatctgct
    12061 gtaacaattg ctttaaaaca ttttcaagat gatcttccat ctataaaagc acttgatcca
    12121 aatgtgccac aagcactgga aaacgtgatt ttacgggcaa cggctaaaga acctgcagac
    12181 cgttataagt cagccgagga aatgtctgat gatctttcta cagtattatc accagctcgt
    12241 gcaaacgaag aaaaatggca gcctcatgtg atggataatg aaacaaaagt tatcacaccc
    12301 cttacggaag atgcaccaat gcctgattca ttcaaatcta tgcctctgcc aaaagacaag
    12361 ccagaaaacg aaaccttacc agaggaggaa gaagttctgc ctgatcctaa aaagaaagga
    12421 cagaaaaaat ggtggctgat cctattagct attcttgctg ttttaggaat cggaacagct
    12481 gtattctttg cttctggcgg gcgaggagaa gttgttgttc ctgatgtttc tgatctttct
    12541 gaagcttctg ctagagaaac actcgcaaaa gcgaaattag aagtagcaac aaaaacagaa
    12601 gaaattgcag atgacaaaat cgaagaaggt aatgtagtga agacagaccc ggcagcggga
    12661 acgacagtca agcaaaaacg cgaagtcact ctgtatatta gtagcggcac gaaaaaaatc
    12721 aaattagatg attacagtgg taaaagttat gaagatgccg aagcaagttt gaaagaatta
    12781 gggttttctg ctgacttgat tcaaaaagaa gaggaattca gttcagaggt agaaagcgga
    12841 atgatcattt cgcaatctcc atcagaagat acagaagtcg atcctaaaac agacacgatt
    12901 actttcacag tcagcaaagg accagaaaca gtgactttga gtagtcatgt aggagaaaac
    12961 tacgaaactg ttcgtaattg gcttgttaca caaggattca atatcaataa tattagtgct
    13021 acttatgact atagcgacac tgtaccatca ggttcgatca tcagtcagga tccagcctcg
    13081 ggtgaagttg tagcagaaga aacttacatc aattttgtcg taagccaagg aacagagcct
    13141 aaattgaatg atatctccgg ctatacaaaa agcgaagcac aaagttattt agctagtgtc
    13201 ggtgcagaat atatcgggca tgagacttcc gaatattcaa acacggtgga taaagataaa
    13261 gtgattcgta cagtaccagg ggcaggaacg acaattacca aaggaatggt tgtgaacgta
    13321 atttactcta aaggaccaga tccagcgtct tctagttctg aaaaagactc ttcagacagt
    13381 tctagcagct caagtagctc cagtagcaca agcaactctt caaaagaaga atcttccagc
    13441 tccacaagtt catcagctag cacctcagaa agttcaaaat aagtgctgaa taaaatatat
    13501 cagaagggaa tgcgacattg atttgttgca ttctcttttt tgtgtttcta tctcttttga
    13561 tcaattttca agccatatac tttgagaagt ttgcatggaa taacacctac tttcctcttc
    13621 gtatggtaaa ataaacaaaa acggaggtgg cacttatcaa aggacaaatc agaaaagcaa
    13681 tcagcggttt ttactatgta tacgcaaacg gagagaccta tcaaacaaga ggaagaggaa
    13741 atttccggaa tcggaaaatc acgccgcttg tcggagatca ggtgatcttt gagagtgaaa
    13801 atcaaacaga cggctatctt ctggaaatct tgccgagaaa aaatcaatta gttcgcccac
    13861 cagtcacaaa tgttgatctt ggaatcattg tcacaagtat cgtagagcct gcattttctt
    13921 ataatctact tgaccgcttt ctagttacct tggaatacga gtcgatcgaa ccgattattt
    13981 ttttgacaaa gaccgacttg tcagacgacc cagaaaaaat cgaagagatc aagcaaacct
    14041 atactaaaat aggctatccg gtgattgtac ccaatcatac gggtgatacg acagaactga
    14101 tccgttactt cccagaacgg ctatcggtct ttatgggtca gtctggagca ggaaaatcga
    14161 cgctactgaa tcaaatatca ccggaactga atttagcaac aggagagatt tctgatgcac
    14221 ttggaagagg acggcataca acacgtcatg tggaactgat tcctatctat ggcgggttag
    14281 tagcagatac accaggattt agctcgattg actttttgac aattgaagca ggagaactgc
    14341 cgagacaatt tcctgaattt gtagaagctt ctgtccattg caaatttaga gagtgcatgc
    14401 atgctaaaga acctggctgc gaagtaaaac atagagtaga aacaggtggt atcgcacaga
    14461 cacgttacga caattatttg caattcttac aagaaatcga aaaaagaaaa ccaatgtatg
    14521 caaaaaaaga aggtaaacga aaataggagg aaacaagaat gaagatagca ccatccattt
    14581 tgagtgcaga ttttgccaat ttacaaagag acattgagtt agtggaaaaa ggaggcgcag
    14641 attacatcca cgtagatgta atggatggcc gatttgtccc aaatatcaca ttagggccaa
    14701 atattgttca ggcaatccgt cctgttacta aattaccgtt agacgtccat ctgatgatcg
    14761 ttgatccaga aaactacatt ccagcatttg caaaagctgg agcagatatc attactgtcc
    14821 acgtcgaagc aactcctcat attcatcggg cacttcaaat gacaaaaagc ttaggagtta
    14881 aagctggagt agttatcaat ccaggaacac cagtctccat gatcaaacat gttttgcctt
    14941 tggctgatca agtactagtc atgactgtca atcctgggtt cggcggacaa agctttattg
    15001 aagaaacagt agaaaaaatt acggaactcg ctgatctacg tagagagaac aattggactt
    15061 atgcaatcga agtagatggc ggaatcgttc cagaaacagc aaaaatctgt aaagatgcag
    15121 gggcggatgt cttcgttgca ggatcatata tctatggagc cgaaaatcca gtcggacaaa
    15181 tcgaacgatt aaaagaggca ttagactaaa tgaaaatttt attagctgct ggaggtaatc
    15241 cgcaaaactg gccgcagtct ctgctgtcca aatacgatgc ctatgtcggg atagaccgtg
    15301 gtgcgctgta cctgcttcaa gcaggctacc cagtagatct ggcagtgggt gattttgatt
    15361 cattgtcgaa cgaagagcag aaggaagtat ttgcaaaagc caaagagtat acccgttccc
    15421 ctgcagaaaa agacgataca gatacacagt taggtatctt aaaaacattt gaacgttacc
    15481 cgcaagcgga agtcactttg attggagcta cgggcggaag attggatcat cttttagcca
    15541 atctctggtt aggtatggaa cctcgcttca aaccctttgc ccatcagctt attatcagag
    15601 attgtcaaaa ttatttgtct tattatttgc ctggagagca tatagtaaga cagataccag
    15661 atatgaagta tttagcttat tgctgcttga ctcccgtctc gaatcttaca ttaaaaggca
    15721 gcaagtatgt attggaaaat aaagaagtag aatatccgac atcttatgca agtaacgaat
    15781 ttctttcaga taccgcagaa ttttcttttt cagatggtat gattgcagtt attcaaagca
    15841 aagattgatc cataaacaaa taaaaaaatt tgtctttcag gctaaaaatg acagaatcta
    15901 ttatttgcta aaaaaaagct taagaggagc aacttacctt ttgtttcacg gcatttagtg
    15961 ataaaattga acacaagagt ctaattaatt cgaggtgtct ttgtgaagaa gttcaatcct
    16021 aataaaaata ttattattac cttggttatt gttatcatcg tggtgacgat actaagtgtg
    16081 accgctgcgc agcgagcgaa tgaaggaaag cccaatttct tccaatccat cgttaatgac
    16141 agtgttgcaa tggttgataa aacaatctct gccccagtac ggtgggtacg aaatggagta
    16201 gattctgtcc ataatctttt ttcaacttat gccgaaaatg agcggctaaa agaaaaaatc
    16261 gatagctatg atgacgtttc acagcaaaac aagaattacg agagagaaat cgaagcgttg
    16321 aaaaaagaac ttgagttgaa tcagacgctg actagttacg aaaaagtaac ggcaaatgtc
    16381 attactcgtt cgcctgacag ttggcaggac atgctgatcg tagacaaggg ttctaaagac
    16441 ggtatcgaag caaatatggc agtcatgtcg caaaaaggat tgattggccg agtgatcgag
    16501 gtcaatacgg cttcgtctaa aatcgaatta ctgtcatcct ctaatgaaag ctccaatcat
    16561 tttccagtac gggtatcttc ggctaatggc gaagcgtttg gtttgcttaa aaactatgat
    16621 gaaaagctcc atgccttagt ggtgacccaa ttaactggtg atacggatat caaagaaggg
    16681 gatgttgtcc agacatccgg tcttggaggg aattctccag ctaacttgcc gatcggtacg
    16741 gttattaaaa cgaaaccaga tagttatggg ctggatcggg aagtttatgt gaaaccttat
    16801 gcagaaatgt atgacgtgtc agttgtgacg attgtccaac ggctagcgga ggattagtcc
    16861 atgttgaaga aagaaacaat gaagtactat ctgccaatcg ttttgttctt tttgatgttg
    16921 atagatggtc atttaacaag aatgctaggg gagtggtcga aaggcaccta tatgtcaaat
    16981 gcccactttc tgatattggc attattatgt tgcagtatgg cgtttgaaaa acgttattta
    17041 ctgattacca cgattgttct cggggctatc tatgacgctt actatattgg cgttatcggt
    17101 atctatgcag tagctctccc tttaattgta tggttgatgt atgtaatgaa agacgttatc
    17161 catgtcaaca tctttactga atttttcagt atgatcatct ttgtcacggg ttatgaattg
    17221 tttacgatgg tggtccagtt gatttttaaa ttagcagtag taaataacac gtattttatt
    17281 acaaggtttt taggacctac actgctgttg aacatgatta tatttgtatt attcattttt
    17341 ccctttaaga aattattcag tgatgaataa tttctttttt tatttttagg tcgaaagcga
    17401 aaaagaatcg ttgttatctt aagaaatgct agacttaacg cggctttttc atgatcattt
    17461 tctgaaacga acagttttgt catttttaaa agttgttttg aaacattttt gtaacataac
    17521 tattatatcg ttgacacact gctatggtac aatttttata tcgttaagaa agacttaaat
    17581 atatttagat atttattaaa ttaagccagt cggaggaatg aagagtgaaa aagagtttaa
    17641 tatcagcagt aatggtatgt tcaatgacct tgactgccgt agcatcaccg atcgctgccg
    17701 cggcggacga ttttgattct cagatacaac agcaagatca aaagattgca gacttgaaaa
    17761 atcaacaagc agatgcacaa tcacaaatcg atgccttaga aagccaagtt tctgaaatca
    17821 acacacaagc acaagaccta ttagcaaaac aagatacatt gcgtcaagaa tctgcacaat
    17881 tagtaaaaga cattgcagat ttacaagaac gtattgaaaa acgtgaagat acaatccaaa
    17941 aacaagcacg cgaagcacaa gtaagcaaca caagctcaaa ctacatcgat gctgtattga
    18001 atgctgattc attagcagat gctattggac gcgttcaagc aatgacaacg atggtaaaag
    18061 caaacaacga cttgatggaa caacaaaaac aagataaaaa agctgtagaa gacaaaaaag
    18121 ctgaaaacga tgctaaacta aaagaattag ctgaaaacca agctgctttg gaatctcaaa
    18181 aaggcgatct tttatctaaa caagctgatt tgaacgtact gaaaacttca ttagctgctg
    18241 aacaagcaac tgctgaagac aagaaagctg acttgaaccg tcaaaaagca gaagctgaag
    18301 cagagcaagc tcgtattcgt gaacaacaac gtctagcaga acaagctcgt caacaagctg
    18361 cacaagaaaa agctgaaaaa gaagcacgcg aacaagcaga ggctgaagca caagctactc
    18421 aagcttcatc tactgcacaa agctcagcaa cagaagaatc atcagctaca caatcttcaa
    18481 tgactgaaga atcatcatca gctacacaat cttcagcaac agaagaatca acaacacctg
    18541 aatcttcaac agaagaatca acagcgcctg aatcttcagc aacagaagaa tcaacaacag
    18601 cgcctgaatc ttcagcaaca gaagaatcaa caacagtgcc tgaatcttca gcaacagaag
    18661 aatcaacaac agtgcctgaa tcttcaacaa cagaagaatc aacaacacct gcgcctacaa
    18721 caccatcaac agatcaaagt gttgatacag gaaacggcac aggaagtagt actccggctc
    18781 caacgccaac accaacacct gaacaaccaa aacctgtaac acctgctcca gctccttctg
    18841 gaagtgtgaa tggtgcagca atcgtagcag aagcttacaa atatattggt actccatatg
    18901 tttggggcgg taaagatcca agtggctttg actgctcagg gttcacacgc tatgtttaca
    18961 tgcaagtaac tggtcgtgac atcggtggtt ggacagttcc tcaagaatca gctggaacaa
    19021 aaatttcagt ttctcaagca aaagctggag acttgttatt ctgggggtca caaggcggaa
    19081 cttaccacgt agcgattgct ttaggcggag gacaatatat ccatgctcct caaccaggcg
    19141 aaagcgtaaa agttggttca gttcaatggt ttgcccctga ctttgctgtc agcatgtaag
    19201 aatgat
//
LOCUS       DAZAOD010000051        18812 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000051 DAZAOD010000000
VERSION     DAZAOD010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.052"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..435
                     /locus_tag="ACHDPO_001742"
     CDS             <1..435
                     /locus_tag="ACHDPO_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFN3369363.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="ACHDPO_001743"
     tRNA            complement(759..842)
                     /locus_tag="ACHDPO_001743"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="ACHDPO_001744"
     CDS             1370..1870
                     /locus_tag="ACHDPO_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3369364.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="ACHDPO_001745"
     CDS             complement(2060..2404)
                     /locus_tag="ACHDPO_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFN3369365.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="ACHDPO_001746"
     CDS             complement(2558..3478)
                     /locus_tag="ACHDPO_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFN3369366.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="ACHDPO_001747"
     CDS             3665..4156
                     /locus_tag="ACHDPO_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFN3369367.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="ACHDPO_001748"
     CDS             complement(4180..6555)
                     /locus_tag="ACHDPO_001748"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFN3369368.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="ACHDPO_001749"
     CDS             6881..7507
                     /locus_tag="ACHDPO_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFN3369369.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="ACHDPO_001750"
     CDS             7530..8234
                     /locus_tag="ACHDPO_001750"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFN3369370.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="ACHDPO_001751"
     CDS             8426..9259
                     /locus_tag="ACHDPO_001751"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFN3369371.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            9456..11384
                     /locus_tag="ACHDPO_001752"
     CDS             9456..11384
                     /locus_tag="ACHDPO_001752"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFN3369372.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            11522..11977
                     /locus_tag="ACHDPO_001753"
     CDS             11522..11977
                     /locus_tag="ACHDPO_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFN3369373.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            12057..12185
                     /locus_tag="ACHDPO_001754"
     CDS             12057..12185
                     /locus_tag="ACHDPO_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369374.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            12447..12716
                     /locus_tag="ACHDPO_001755"
     CDS             12447..12716
                     /locus_tag="ACHDPO_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369375.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            13116..13370
                     /gene="rpsT"
                     /locus_tag="ACHDPO_001756"
     CDS             13116..13370
                     /gene="rpsT"
                     /locus_tag="ACHDPO_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFN3369376.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(13459..14505)
                     /gene="holA"
                     /locus_tag="ACHDPO_001757"
     CDS             complement(13459..14505)
                     /gene="holA"
                     /locus_tag="ACHDPO_001757"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFN3369377.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(14543..16816)
                     /locus_tag="ACHDPO_001758"
     CDS             complement(14543..16816)
                     /locus_tag="ACHDPO_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFN3369378.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(16809..17348)
                     /locus_tag="ACHDPO_001759"
     CDS             complement(16809..17348)
                     /locus_tag="ACHDPO_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFN3369379.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(17484..17702)
                     /locus_tag="ACHDPO_001760"
     CDS             complement(17484..17702)
                     /locus_tag="ACHDPO_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFN3369380.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(17699..17944)
                     /locus_tag="ACHDPO_001761"
     CDS             complement(17699..17944)
                     /locus_tag="ACHDPO_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFN3369381.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(18060..18788)
                     /locus_tag="ACHDPO_001762"
     CDS             complement(18060..18788)
                     /locus_tag="ACHDPO_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFN3369382.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
BASE COUNT         5782 a         3642 c         3309 g         6079 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct tatttgagaa atgttctggt
     9301 tttttatttt ctttaataat aatcattata aataataaaa acaacatcaa gcttaatcac
     9361 caaatgataa ccattatcgt tctcatttag ctgttattat tatcaattac atttttatta
     9421 tgctatcctt gttttgacaa ggaggtctaa taacgatgac taatcagaaa aaagcttttg
     9481 cagcaacaat cggctgcctt ttatttatga tcttcggttt tatcttcgac cgattctctc
     9541 ttaccatcac cccacttttt tatatcagtg ccattatcat cggtggatat aaacaaacat
     9601 cggaaggctt gaaagaattg tggaatgatc ggacactgaa tgtggattta ttgatggctt
     9661 tagctgctat tggtgcctgt ttgatcggta attactttga aggagcaatg ttgacattca
     9721 tcttttgttt aagcggtgca ttagaggaat acacaactaa taaaagtcaa aaagaaatta
     9781 ctgctttgat gaatcttcaa ccacaaaaag cccaattatt aaaagaaaat ggacaaatgc
     9841 aagaagtaga tgtttctcaa ctaaaggtgg ataacttggt atttgtcgct aaaggagcag
     9901 ctgttccgat agatggcttt ttagaaagca cacaggcaac gatcgatgag tctgcattaa
     9961 gcggtgaatc tgtgcctgta gaaaaatatt taggcgatga gatgtatgca ggaacgctga
    10021 atcaaggaaa tcccatcacg attcgagtaa caaaaacgag ttccgaaact gtctttgcta
    10081 agattatcca attagtagaa gaagcgcaga atacgccaac tcaaacagct tcatttatcg
    10141 aacgaatcga aaataattat gtaaaattga ttttgcttgc tgttcctcta atgatccttc
    10201 tcccccactt tttcctaggt tggagttggg atgaaagctt ttatcgagga atggtattat
    10261 tagttgtggc ttctccttgt gcgcttgtcg catctgctac accagcttct ctagctgctc
    10321 tttcaaattc tgcaaaaaat gggattttaa tcaaaggcgg tatccattta gaaaagcttt
    10381 ctgaattaaa agcgattgcc tttgataaaa caggaacgct cactaaagga aaaccagttg
    10441 taactgacag ctttttcttt gatgaaaagg atttggcaca acaacttctt gttgctatgg
    10501 aacaaaaaac gacgcatcca cttgctcatg cgattttgca atatttcgat tgcacaatac
    10561 ctgaagaaat ccaatactta ccaatagaag aaattactgg ttttggatta caaactacct
    10621 atttaggtgc gcaatggaaa gttggcaagc acgcatatga tcctgagacg atgataatca
    10681 gcaaagagat tgcggaaatg atcgaacgtt tggaaaatca aggcaaaacc gtgatttatc
    10741 tttctaaaga tcagcagtta attgctgttt taggtctgct agatattcca aaagcaaata
    10801 cccaacaagt aatttcctac tttaaatccc aaaacatcca tacaagtatg ataaccggcg
    10861 accattctgg cacagcaaag gccattgctg aacaagtagg gattgaacat tactatgcaa
    10921 gctgtactcc ggaagaaaaa acacaactag tcaaaaaaga gaatgaactt taccaagtaa
    10981 atgcgatggt tggtgatgga gtcaatgatg cgcctgcttt agcagccgct tctttaggtg
    11041 tcgctatggg gcaagggaca gatgccgcta tggatatcgc agacatcgtc ttaatgaaaa
    11101 gcgacttaaa taaatttgtc tacagtcatc ggctatcttt aaaaatgcgg cggatcatca
    11161 aacaaaatat tattttttcg attcttgtta ttctcttgtt gattgcttct aacttcctgc
    11221 aatttttaaa tctacctctt ggagttgtag gacacgaagg aagcacaata ttggttattc
    11281 tgaatggctt gcgtttacta agacctttac ctgatctttc tgattcttca aaaaaatgta
    11341 agtcttgtcc actatacaaa gcgcggctgt cttctgtcaa ataagcaaag tgttttttta
    11401 tgattttgtt tattttatga aaaaaacagc ttatgaatag gtcttgaagg atgaattcct
    11461 acttttgtaa ctttctaaaa acatgttatg attgtttcga agaaagtgag gaatatattt
    11521 catggaaagt tggctttttt taggaattat tttacttgta gcaattttag ctaaaaatca
    11581 aagtctgatg atagcggcag cttttgtttt gattatgaag ctcataccag cctcccgttc
    11641 ctttttccct tggcttcaag gcaaaggaat caatattggg gtgacgatca tcacagcggc
    11701 tattctaatc cctatcgcaa caggagaaat cggtctacgt gatctattag aagcctttaa
    11761 atcccctatt ggctgggtag ctgttttttg cggtgggcta gtggctgtct tatcttccaa
    11821 gggtgtagga ttgattgctt ctgatccaca aatcactgtt gcacttgttt tcggcacgat
    11881 tttaggtgtt gtcttcttaa gaggaatcgc cgccggaccg gtcattgctt ctggtatcac
    11941 ttactgtatc ttacaagtat ttgctttagg aaaatagaac aaattttgtc tattttagga
    12001 gattcttaac acccccaatt tactgatccg tgatatactg acaacgaggt gatacaatgt
    12061 tcgaaaaatt aaagtatttc ataggaacaa tcggctggtt tcttctagcg gtacttttga
    12121 ttctgggctt agcttatcta ttatttcctg atttgataca aaatgtgttt gatactgctt
    12181 tttgattgac ctattaaaac gatatagggg atgctcctgc gatgcagggg ctttttttaa
    12241 tcaatgtttt gtaataattt aggccgtgcc aatgagactt cctatagaat tcgatgctct
    12301 tttttctttt tggctcttct gctctttttt gttatactag attacagtgg acaaaagaaa
    12361 gaatgatcgc atccacttca acgaatatca aaatggaaga attagtgcct gttttcaggt
    12421 tactttgaaa agaaaggaag acgcttgtgg aaacttttga aggtctttta attgatacgt
    12481 acgttttaca agaacagcca atgatgctga ctgggatcaa cttgcagctt gaggaccgtg
    12541 tgatcaatgg cctgcttaaa gatcgctatt tggcaaaata tatcttacgt ttgcccctaa
    12601 ataaatatgt gctggaagta agtggcaaat ggaaccgtcg gaaccagttg gtcataaaaa
    12661 aaatgttgat aaaaaatatc gatgaataca ttaaaataat cggtacacca gaatagcctt
    12721 tactgatcaa aggatactgg ttataaaata actgcagttt cttaatagaa aaacaaagaa
    12781 caacagggaa tcgtatccct tttcaaaaaa aactttgcaa acggttctct ttgttatata
    12841 ataacttagt accaaacatt cccattcaaa ctttgtttaa atagataaat aaaaatctag
    12901 tttggtttga cgctattgcc tcccacaata gcgtcttttt gatttttttc agcttgtact
    12961 atccgttttt actgaaaaaa aatcctaata aaagactgtt aaggaaaaaa acttgtcatg
    13021 ttcatattgc aaagcacgct gcctttaggt ataataatga atgttgaatt atgcggtaac
    13081 acgcgtaaga acttaagtta tcggaggtga aactaatgcc aaacattgaa tctgcaatca
    13141 aacgtgttcg tacaagcgaa aacgctaatg tgaaaaattc atctcaaaca agcgctatgc
    13201 gtactgcaat caaaaaattt gaagatgctg tagcttcagg tgctgacaac gtagatgcgt
    13261 tatataaaga agctgttaaa gctattgata tggctgaatc aaaaggtcta atccacaaaa
    13321 acaaagctaa ccgcgacaaa tctcgtttaa gcaaaaaaat cgctaaataa aagaatcggc
    13381 ttcggccgat ttttttattt gtcaaaaaaa ggacaaaaac aaacgacctt cccgcatgct
    13441 ttgccctcgt ctttcttctt atcgatttct taacaactgc cctgtgcgca aaacgaatag
    13501 ttgaaaactt aattcttttt cgatttgtcc cgttttgatt tgataatcca tctcaactaa
    13561 ttgatcaaac aactgtacca gcaaatgttc atcgaatttt tttacttcct gcatggcaag
    13621 ttttacacga tatggatgga ttttcaatgt ttcagcaata tttgcctgct gataaccaat
    13681 ctttacaaga aattttgtct gtaaaaataa acgtaattga gaaagcaaaa tcgcattaat
    13741 tttgattgtt tcttcccctt gcataactaa atcttcgtat aaacgcaaag cttgttccgt
    13801 cttccctttt aaaatatatt gggtcatgtc aaaaatatta tgttctaacg ttttaggaac
    13861 taattcttct acttctctta ccgtgatttg ctgttgattt tgtccataaa ggaccaattt
    13921 ctgtaactct ctcatcattt tggataaatc taagtcggtc aacctcaaga ataaatcaat
    13981 tgcacttcgt tccattttga ttgaggaatt ctctaaggta ttcatcagat attgacgtac
    14041 ttctttttca ttcaactgtt ggacattgat gataattgct gtttttttca attgtttcgt
    14101 tacttttttc cgttcatcca acttttcata tggcgcaaag aatactaata cagtcgattc
    14161 taatggttct ttcaaataag ccgtcaataa atcagtattt tgttcgattc cattgtttac
    14221 tttttcacct gttaaaaaat aaggattctc tacgaatact aaccgttgat ctccgaaaaa
    14281 cggcaacgtc tctgcttcag ctactacctc atctaaactt gcattttcca tgtcaaaact
    14341 taaaaaattt aagtcatctt cgccctctaa ttggattttt ttgacaattt ctgtccgaac
    14401 ttgatcttgg agaaactttt ctgttcctaa aatcaagtaa caagatgcaa gtttttcttt
    14461 acgtattttt tgtaactctg cttgtatact caaattactc accactttca aaaattatcc
    14521 taccatgagc agatgagaat tactagtcta tcattgtttc cactagccca tgaggatgaa
    14581 aaactggatg ccagcgatag gtgatcattc cttgttgatc cgttcgccat gtttttatct
    14641 gattttcttc tagtgtctcc aatacttcgc tgtgcgggtg accataacga ttatttacgc
    14701 cgcaggatat aatcccatgt tttgcttcaa tatgggaaag aaaatctgtg ttacttgacg
    14761 tacggctacc gtgatgacct aatttgacta catcggcttt cagattagga taaatcaaaa
    14821 gcaattgttt ttccattgct tgattcaaat ctcctaaaaa taaaaagcgc ctattgttat
    14881 attccatcca tagaccaatc gaatcttcat ttcttccctc tcccttttca aaaggagtca
    14941 atacataaag atcataataa ccgctgatcc tgtccccatg tttgatttca atgatctcag
    15001 taccattttt ttgagcttca gataaatgcc tttgtaatgg ctcatttcgt ccagcgcccc
    15061 aaccgatata aatttttttg atagtaaaat gctgagataa cgtgggtaat tctcccacat
    15121 gatccgtatc gtcgtgtgtc aagatgagtt tatcgattac acttatcccc tgacctttta
    15181 gatatggaac gatatttctt tcagcaggag gacgtatcat accttgcgcc cacttttctc
    15241 tttcaaagtg taactgacct ccagtatcga tcaaaatcgt ttcttttcga aaaggacttt
    15301 gcaaaaagat actgtctcct tgaccgacat cgataaaagc gatcgttgaa gaaaagcgta
    15361 aaaatggcaa agtcaaaaaa ataaaagaaa aaagaccaac ataaaacaag tgtttcacag
    15421 gttgttcttt caacctatcc atacaaatca gtaatccgaa aatatacatc ccagatagca
    15481 caaggggcaa acgtcctata atgagagacg accctgaaga aaaatcgatt attcgctcaa
    15541 ataagattaa tccctcttct atcagcaaaa gtaaagtttc cggcagccag cgattgaaga
    15601 gtgtgagaaa taacacacca ggaagaaaaa gaaacttgaa taccggtgca atcagtaatg
    15661 taaaaagact acctaaaata ggccactcat aaaaatgcca tacaatcaac ggcatcgtga
    15721 tcatagtaaa caggacgtga gaggccgttt ttttcaacca atctccatca aaagaaatca
    15781 ggataaacaa aaaactcatg aaaaaactaa gctgtccacc cgcatgaaaa agaaatcgag
    15841 gatcaaatag taaaagaagc caaaagacaa ctgcaaataa gtccatggtg gaataatgct
    15901 tattcagcaa tttgactagc aatcgcaata aaaacagcaa actagcacgc aaaacagaaa
    15961 tagaacttcc tgcaatagaa acataacaga tagttagtag actcaacgga ataatactga
    16021 cgtgtagtgg ccatccgata cgtcgaaaca aataatacag ccaccctaaa taaaattgga
    16081 tgtgtagacc cgatagactg aacagatgca gcaaaccact ctccctaaaa atttcttctg
    16141 gttctctgaa tcctgcatct ttatagcccc ataataaaga attaatatat acacttgttt
    16201 tttgcggaaa ttcagattgg acaaaggaga taaaagatcc tctttttctc tgaagccagt
    16261 ttcgccagtg attttgcatg gtgatctgtt caatcttttg aatttggaac cgtccagaaa
    16321 ttctatggtt cctgaagtaa gcttcttggt caaaattata aagattccgc ttttttgctg
    16381 gagagatgaa ctcgccttca gcagtcaatt ctattccctt tcctcggaag ttaagccatg
    16441 ttttcaattc tgcttctgtg tttacttgat aagaaagctg gagcttttgt ttattctctg
    16501 ataaccttcc ttccattgtc aaaaaattac catttgcacg aatcgtatct gtaaatacag
    16561 taatttgcgc agatgttgtt ttttcctcta aaaatgaata ctcttgtagc ctataagaaa
    16621 tggataccgt tatgctacac aaaatacaca agtacgcgat aaaacgtcct tcttttagcg
    16681 aaaaccataa aaaaattccg gcaagaagca aacgataacc ccaattgtca gtgtaataca
    16741 acaaacagat aatcatcgac gtaattgccg gaaaaatcaa ccgatttcga acatgccttt
    16801 ctaaaacgct agacatgttt tcctgttaat tcattttgaa gttttgaaaa atgctgtgag
    16861 tctaaagcaa cttggtgtac agatacacct aattgttcga tcaacgcttg ggcataagga
    16921 tcatttcgat agtcatggag ataattgatc cctttcacac cagcttgcaa caaagccttt
    16981 gtacaggcca aacatggaaa atgtgtgaca tagatttctg aaccttccgt cgggatacca
    17041 agttttgcac actgtaggag tgcattcatc tctgcatgga tcgttcgcaa gcagtgtcca
    17101 tccacgacgt aacacccttc atctatgcag tggacatctc cactgactgc tccattatag
    17161 ccgccagcaa tgatcctttt ttctcgaacg agtgtcgctc ctacttctaa acgtgtacac
    17221 gtactacgta aagataacag tactgcctga gccataaagt actggtccca aggaatgcgt
    17281 tcattatgtg acttatcagt aactttttct ttattcgtat cgcatgcttt tgaagatttt
    17341 tctaacatgt tttatattcc tccgtttttt caagttgatt aaaaagtact cattgcttaa
    17401 acaaaatatt ctttaaatat aacgaatcat cctgtctgac aaaagatcct acccttcact
    17461 gccgaaatga agtccgtcat ccattagccc attataaaaa ttcttcgaat ccatttgttc
    17521 aagaaattcc gtataaaaat cgatacttca caatcatggc gttttgctac ttctgtgaga
    17581 acagagatat attctttgat caacttgtta ttccgatatt tttgttttgt ctcatcgact
    17641 gctggtggcg tgataaagaa agcatgatca gaactatagt cttttttcag ctgaactatc
    17701 atccactgca gattttttgg tacgtttctt tagaaagttg tttatgctct gctagatcat
    17761 tcgtcccaat gagaataaat actttatctg ctgtatagct aagtacatct ttggcaaagc
    17821 gttctcgtag agcttgactg ttattgccgc tgacagccgt attcataata tgaatcccag
    17881 atattttatt ttggagatag acattcagca ttggtttttt taatgtttct ttgcgaacaa
    17941 tcaagctatt tcctatccaa aaatactacc tcctcgtcct gccaagctct tagaattgga
    18001 ttattcttag tatccattag cgtccattta ttgctcgtgc cagtcgattt tgaatcattc
    18061 tatttaattg taacgaagtt ttttagtttt tcaactgtct tttcaccgat accagaaatc
    18121 tcctgcaggt cttccacttt ctggaaggat ccgttttctt ctctaaatcg aatgatttct
    18181 tgcgctttga ctgatccgat cccaggaatc tgctgaagtt ctgatggagt ggctgtattg
    18241 atatttattt tgggaggctc ggaatctgct gtaggctgtt ttccttccga ggatgccaac
    18301 tgatcaagat gttctggcag ctcttcacct acagcaggga tatataggac ttgctgatct
    18361 tctatcttcg cagaaaagtt gattcgatcg ctatccgctt cttctaataa tccacctgca
    18421 cgctttagta catcatagac ccgttcttct gaagaaaagg aatagatacc aggctccttc
    18481 acacttcctt tgatatcggt gtacatgacc tttggacgag catcctcttc tacatcgttt
    18541 ccttcagctg atggatcttc tccactggaa ctaaacgaag aaagtatttc ttttgcagca
    18601 gtctcttctg tttctctata aaatagcaaa tttgataata aaaaaccact tgcgatacaa
    18661 aagataagaa ctatcataga catccaaatg atcaatttgg gtgaagctag tattttcttg
    18721 ctgatttttt ctatcattgt tcttttttca aagaatgacc agtaaaaatc attcattact
    18781 cctttcattt aaaattgaag aaacagtgag ct
//
LOCUS       DAZAOD010000052        17989 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000052 DAZAOD010000000
VERSION     DAZAOD010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.053"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(404..766)
                     /locus_tag="ACHDPO_001763"
     CDS             complement(404..766)
                     /locus_tag="ACHDPO_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFN3369383.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            989..1741
                     /locus_tag="ACHDPO_001764"
     CDS             989..1741
                     /locus_tag="ACHDPO_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFN3369384.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(1881..2804)
                     /locus_tag="ACHDPO_001765"
     CDS             complement(1881..2804)
                     /locus_tag="ACHDPO_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3369385.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(2819..3091)
                     /locus_tag="ACHDPO_001766"
     CDS             complement(2819..3091)
                     /locus_tag="ACHDPO_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369386.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(3435..4622)
                     /locus_tag="ACHDPO_001767"
     CDS             complement(3435..4622)
                     /locus_tag="ACHDPO_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFN3369387.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            complement(5035..6660)
                     /gene="groL"
                     /locus_tag="ACHDPO_001768"
     CDS             complement(5035..6660)
                     /gene="groL"
                     /locus_tag="ACHDPO_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFN3369388.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(6711..6995)
                     /gene="groES"
                     /locus_tag="ACHDPO_001769"
     CDS             complement(6711..6995)
                     /gene="groES"
                     /locus_tag="ACHDPO_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFN3369389.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            7220..7882
                     /locus_tag="ACHDPO_001770"
     CDS             7220..7882
                     /locus_tag="ACHDPO_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFN3369390.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(7958..9250)
                     /locus_tag="ACHDPO_001771"
     CDS             complement(7958..9250)
                     /locus_tag="ACHDPO_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFN3369391.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            9420..10049
                     /locus_tag="ACHDPO_001772"
     CDS             9420..10049
                     /locus_tag="ACHDPO_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFN3369392.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(10152..10961)
                     /locus_tag="ACHDPO_001773"
     CDS             complement(10152..10961)
                     /locus_tag="ACHDPO_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFN3369393.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(11016..11885)
                     /locus_tag="ACHDPO_001774"
     CDS             complement(11016..11885)
                     /locus_tag="ACHDPO_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFN3369394.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(11886..13202)
                     /gene="yycH"
                     /locus_tag="ACHDPO_001775"
     CDS             complement(11886..13202)
                     /gene="yycH"
                     /locus_tag="ACHDPO_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFN3369395.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(13199..15034)
                     /gene="walK"
                     /locus_tag="ACHDPO_001776"
     CDS             complement(13199..15034)
                     /gene="walK"
                     /locus_tag="ACHDPO_001776"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFN3369396.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(15039..15743)
                     /gene="yycF"
                     /locus_tag="ACHDPO_001777"
     CDS             complement(15039..15743)
                     /gene="yycF"
                     /locus_tag="ACHDPO_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFN3369397.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(15933..16793)
                     /locus_tag="ACHDPO_001778"
     CDS             complement(15933..16793)
                     /locus_tag="ACHDPO_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFN3369398.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(16780..17349)
                     /locus_tag="ACHDPO_001779"
     CDS             complement(16780..17349)
                     /locus_tag="ACHDPO_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFN3369399.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            17730..17802
                     /locus_tag="ACHDPO_001780"
     tRNA            17730..17802
                     /locus_tag="ACHDPO_001780"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17763..17765,aa:Lys,seq:ctt)
BASE COUNT         5204 a         3786 c         3070 g         5929 t
ORIGIN      
        1 tttttcttac ttgataaaat aagtagattt tcctactaca atcgtagccg ttaagatacc
       61 gatgattgaa caaatataac caaatgtctc tacaacataa tcaatggcaa aagtttttga
      121 agcaataata cgtctttcct tttttgcttc ttatccccaa agaaacggat ataacttatt
      181 atgtattgaa tttttttgga aaggcgaatt atgacaagat ataccttgcg ttgaaaaaac
      241 tcgcggaaaa aatatcacac gtttttaaaa agatacaaag taagaaagca gctgtcaata
      301 gaatggaaac aaaaatggcg agacatcaat cagtctcgcc ttgtttttta ttgtatacat
      361 tagatatgga gcaggttacc ataaagatga ttattagtcg ttattaaata gaatccttcg
      421 tatttttttg ttctatcact acaatatctt tatttggacg tttgaattgt attccggcac
      481 gttctagctc ctgtttcact cctacatgga ctttgacatc ttctcgtgtc atttttaaaa
      541 cgtgatgaat cgcatagtcg atttcttgcc ttgtgatttt tttcttcgta ttgatcatca
      601 cgacttgctt tttatcatat gtgtctacca atagcagttg tgttcgatct aacgaaaata
      661 atttgtaata attaatagcc gtattcccaa aaaagaattc cactacttta ggataaaatg
      721 tcttaatatt taaattacta ttcacaggtg tttcgattag cttcatctca ttcctctttt
      781 ctatatagtc gatttagatc caatcttaag ttatgttacc atctttccta gcattaagga
      841 atcggttaca attgaacctt taaagacaaa aggatttacc ttttatcact taatagtata
      901 acataatttc gtgagaaaaa aatacaattt tttcttgacc atctcgttac gtaaaggatt
      961 atgcttacat ttgtcaggag gaaaaataat ggagtacaca ataaagaaaa tgtcagagat
     1021 atcaggagtc agtccgagaa ccttgcgctt ttatgatgag attggactgc taaaaccagc
     1081 taggatcaat tcttcaggtt atcggattta tggcaaaaaa gaagtcgatc gtctgcaaca
     1141 catcttattt tatcgaacaa tggcattcaa gttggatgat atccaagagg tcttagacaa
     1201 tccatctttt gaccaccaga aagctttaat caagcatcag caaatgttgc tggaaaaacg
     1261 ggcacaaatc gataccctct tgacaactgt ccaacagaca cttgatatgt acgaaggagg
     1321 aagaaaaatg agtgacaaag aaaaatttga agggtttaaa caacaaaagt tgaaagaaaa
     1381 tgaagaatcc tatggacaag agattcgaca aaaatacgga aaaaaaaagg ttacagcatc
     1441 caatgaaaaa tggatgaata tggataaaga aacgtatgaa gaaatgcaaa ctgttgaaaa
     1501 gcagatgtta tttgatctca ctctttactt aaaagaacca gaagatgaaa gcttagcaga
     1561 ccgtatcttc caagctcata agaagtggtt ctcttacagc tggcctgaat atcagccaaa
     1621 agcgcataaa ggactaggaa tgatgtacga agccgatgaa cggttcactg catattatga
     1681 cgagcgaagt ggtcatggtg cagcaaaagc tttaaatgaa attatccaaa aaaaggcgta
     1741 atcttttaca tgatccaaca aaaaagtaca cgtaaaatga cctaataaca aaacagcaga
     1801 cacccaagtt agatttttat gctaactttt ggtgtctgct ccattctttc acaagttttt
     1861 tcatcctact ttaaatatat tcatcgttga ataaacgtat aaggtatttt cactttatcc
     1921 tttttttctg taagaaacaa ttgaaatgcc atttctccgc aagcttccag atggtggtcg
     1981 atggttggga aaccaagaag ctcgctgatc agcaaattat cgcgtccaat caccactggt
     2041 gtcttatctt gcagatagct ttgcaagatg cctgctgcaa ccatatccga atttgtaaag
     2101 acaccatcaa ctccaagctc tttaaaaaag aagcctgctt gttttccttt ctctgcatct
     2161 atacaatccc aaaaaacaag tgattcatca aaagatggaa aaagttgatg acatagctgc
     2221 aaagtgattt ttgagttata acttagcctg ccacttcgcc ccaacgtgat gcccaattgc
     2281 tttatacctt gctgcttcaa ataagtaaga ccttctgtaa ttgattgttc tcgatcaata
     2341 aagacacagc ttgcctgttt tcccttgatt tcttcacaaa aaactagagg tccatatttt
     2401 tgatatgcca ataaatcatc tagtgtattg gcacgagacg taatgatcaa tccatcgaaa
     2461 gctttagctg caaattcttc aagatacctt cgctcttttt ctttatgata gcccgtcggt
     2521 aaaagtgtca ctttgtaatc ataatcaaac gctgcttcaa tgatcccact gatcaactga
     2581 tcaaaatacg gatgattggt ataaggcaga atcactccaa tgcttttcgt ttttccataa
     2641 cttaactgtc tggcatttgc attagggata taatcgactt ctttcatgac cgcaagtatt
     2701 tctttccttt tttcctcatc tacatatgga tgtccattga ttacacgtga aatagtagaa
     2761 actgaataac ctgtgagctt tgcgatatct cgaatgtttg ccactgctgc ttcgccacct
     2821 atacaaaaag attttcttgt aaatagtcta ccacagctgg accgcattca aaaaactgat
     2881 acatttttcc ttcatgcgaa aaactgatcc gctgcccgcc ccaatatata tcttttgtca
     2941 aattttcgat ttcattcatt ggtatttctt ttactatatt cctattcaac ccttgaaaac
     3001 tgtacaacgt taatacggat cccttgaact cgacaaacgc ataaaaataa ttgttcgttg
     3061 tgccatctgt tatctctaca taagtattca ttgcaagccc tccttttgat actttgagta
     3121 tagtgtatga aacgcgtctc atagcaagga gtttgttttg ccaaagaaaa gttttattcc
     3181 tctttcatta ttaccaaagt ctcttatttt aaattgaata cattataatg atactgtaaa
     3241 tatatcttta ttattagtga atggagtcaa gtccacaatc ttgtgtaaaa gttcaacctc
     3301 atcaaaagca caatgttttg cgttgtgaac ctaactgcca tgcctttctt tctgaggaga
     3361 gaggtcagga gcagtagcgc agcgactctt gatgtctctc ctcagaaaga agagactcgc
     3421 acaggttcat ggtgctaaat gttattcgaa ttaaattcta aatattttcg tggagaagcc
     3481 agccactcag tgtctttttc catcaaaagt gttccaatta tccgagtgat ggaattgata
     3541 tttggaaaaa tccgaatcac tcgttctctc cggcgaatct cttcgttcaa ccgttccaac
     3601 acattggttg tacgaatcct tcggcggata ttttcaggaa aagacaaaat ttgaatagca
     3661 tcttcaaagc cgttttctaa aatgtcgcaa gcagcactta attttgaatc acaaccatat
     3721 ttttccaaga agtgctcttt tctttcacgt gtcaattcaa gttcagaggc tttaaagata
     3781 ctcttcaact cgtcttttac atcagaagaa actttctttg gcagcttatc aaaaatattt
     3841 ctcaaaaagt gggcttggca tctttgccag ctcgcaccta aaaagttctt gcgaacagcc
     3901 ttaactaacc ctttgtgtgc atcagaaatg accagtttta caccgaacaa acctcgttga
     3961 acgaacgatt gaaaaacggt atcccaatta tcttccgatt cgccgtcttg aacatcaaaa
     4021 ccaagaatcg tacgtcgtcc atcagaatca atgccgatac caatatatac accttttgag
     4081 acaatacgat gattttccct tactttcata tacagggcat cacacatgaa aaatggatat
     4141 tccgagcctt ctaggctccg gtttctccac tcaaaaacaa atggatccaa ctgtttcatc
     4201 agatttgaaa cgaatgattt agaaacagtc gcaccatccg ttagcagttc aactgtttta
     4261 gttactttgc gagtggagac accagaaatg accatttcaa tcatggcagc gatcaaagct
     4321 ttttcgcttc gctgatatct ttcaaagata gtaggactaa acttaccgtc tctggttcgt
     4381 ggaacatgaa gttctaacgt accaattcga gttgtaaacg aacgatcgta gtaaccattt
     4441 ctttgtgatt gccgttcttc tgaacgttca taggcatttg cctgaatata ttgatttcgt
     4501 tgttcttcca tcagctgatt aaacatgata gtcataagtg tttttgcggt atcattcgca
     4561 ccgctttcgt ttataattgc ttgaatttct tcgctttcaa aagtaaaatg tacttgagtc
     4621 attgatatca gtcctattcg agtatgtttt ctgcaaaaaa cattgtactc ctaactgaga
     4681 tcaatggctt ttttgatgct tcacttttac acaattatat ggacgtaatc gtgaatggat
     4741 atttactttt aatagataaa atattataac tattaaaaat aactattttc attataatta
     4801 cacacaaaaa agagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
     4861 tataaacagc ggaagcagaa gcaactcctt cggaaataag ctgaaattca caaaaatttg
     4921 aaaagcaatt tccgtgaatt tcttcttatt tcttggagtt aaacgcttct gttccagcct
     4981 ctttttatct gtctttcact aatgatcagt tgtagataag caagttgctt tttcttacat
     5041 cataccgccc atcattgatg gatccattgc aggagctgct ggcgctgctg gttctggttt
     5101 atctgcaacg actgcttctg tcgttaataa caaggcagaa acggaagcgg cattttgcaa
     5161 ggcagaacgt gttactttag ttgggtctac gatacctgct tcaaccatgt ttacccattc
     5221 tccagtagca gcattgaaac cagtgcctag ttccacgttc ttcaatttat caacaatcac
     5281 tgatccttca taaccagcgt tttcagcgat ttgacgaatt ggttcttcta aagcacgaac
     5341 aacgatcttg atacctgttg ccacgtctcc ttctgcttct acagcagaaa ctttgctgat
     5401 aacgttcact agagctgtac caccacctga gaccattcct tcttctactg cggcacgtgt
     5461 agcattcaat gcatcttcaa tgcgtaattt taattctttc aattctgttt cagtagctgc
     5521 accaacttta acaacagcta caccacctgc taatttagct aagcgttctt gtaatttttc
     5581 gcggtcaaaa tcagaagttg tttcagcaat ttggtttttg atcaattgca cacgagcttc
     5641 gattgcttct ttttctccag aaccttctac gatcgttgta ttgtctttat ctacaacaac
     5701 tttagaagca tttcctaagt tttcgattgt tacatctttc aattctaaac ctagatcgtc
     5761 agtaattact gtaccacctg tcaaaatagc gatatcttca agcattgctt tacgacgatc
     5821 gccgaaacca ggagctttta cagctactac gttgaatgtt ccacggattt tgttcaatac
     5881 aagagttggc aatgcttcac catctacatc gtcagcaata atcaacaatg gacgtgattg
     5941 ttgcaagatt tgttctaaca atggcagaat atcttggatg ttagagattt ttttgtctgt
     6001 gatcaagata tatgggtttt ctagaacagc ttccattttg tcgttatctg ttaccatata
     6061 ttgtgataag taaccacgat caaactgcat accttctaca acatctagtt ctgtttcgat
     6121 cccttttgat tcttcgattg tgatgacacc gtcgtttcca actttttcca ttgcatcagc
     6181 aatcaaatgt ccaactttat cagaacccga agaaacagct gctacttgtg caatggcttc
     6241 ttttgaatca acaacagttg agatattatg caattcttcg actgctgctt ttgttgccaa
     6301 ttcgatcccg cgacgaatgc ctagaggatt agcacctgca gttacgtttt ttaaaccttc
     6361 gcgaacgatt gcttgtgtca gaacagttgc tgtcgttgta ccgtctcctg caatatcatt
     6421 tgtttttgat gctacttctg atacaagttt tgcacccatg ttttcaaaat gatcttctaa
     6481 ttcgatttct tttgcgatcg tcacaccatc atttgtgatc aatggagagc cgtaagattt
     6541 ttctagtacg acatttcggc ctttaggtcc taatgttact ttcactgtat ctgctaattt
     6601 atctaccccg cgtaacatag ctgcgcgtgc gtcttctgca aatttcaatt cttttgccat
     6661 gattgattca cctcattgat tatttttgat tattttttta tcttccaaat ttactcaaca
     6721 atcgccatga tatcttttcc tgcgacgatc agatattctt ttccttcgta ttttacttct
     6781 gtaccggcgt atttttcgaa cataacttgg tcgcctgctt ttacagcggc aggaactttt
     6841 tcaccgtttt ctaacaaacg gccttcaccg actgcaacaa ctgtcccagt ttggggtttc
     6901 tctttagcag cagaagctaa aacgattcct ccgacagttt tttcttcttc ttttgcgact
     6961 tcgataatga cgcgatcacc taatggtttt aacacgataa atccctccga taactctttt
     7021 tttaatctgt tagcactctt aaccttcgag tgctaaccta catttttaat aatactcatt
     7081 ctccctcttt tttgcaagct tttaaatcaa agaaaagaaa ttttattctg acagctgctt
     7141 attgaaatta tgatataatt gaaatcaatc gatataagct tgccttgcat gcttgttatc
     7201 ccttaaaagg aggaattaca tgtctttaaa aaaatatagc ttcctcagca ttttttgcta
     7261 tggtctaatt tttatctcac ccttgatcct agcttcgata ggacttgtaa aatctacgtc
     7321 tgaattgatc acagcaactg cagtcatgta tatactaggc gccgttgtcc tagctatttt
     7381 ttattttaag caacgtgaac ccttagcgat cgaatcagcg gtaaaaaaag cttctgctcc
     7441 aaagattgtt atttatggat tggttggaat ctttgtcgca ttgattctgc aaagcatcgc
     7501 tgtcatgtta gaatctgtat tgtttggcaa agcaacccct tccgagaata cacaaaatat
     7561 catccagatg atcatggaag cacccgcttt tattttggcg acaactgttg ctggacccat
     7621 catggaagag ttcgtattcc gccgcagtat actggggatc atcagtcgat attcaaattt
     7681 ttgggtcgga gcagtgatca gctctttgct gtttgcgttt gctcataatg atggtcatct
     7741 gctaatctac tttttcctag gtttcttctt cagcctagag tacaaagcaa ctggtcggat
     7801 ctggacatcg atgatcacac acgtaggaat gaacacatta gttgttcttg ttcaattagc
     7861 tgtccaaaaa gggctagtat aaacatgact ataaatactc ctgtcatcct agattggtga
     7921 ttttcccaat ctaaagcgac aggagtattt ttgtttttta gtcgttcatc ttttctgctg
     7981 ctccatcatt ttttgtctgt ctttcctttt tgcagtttgc agaatctatt tttttcaaaa
     8041 atgggaaata aatgaaaaaa ctaattgaca acacgatacc ttgtaaaatc gctgcaggca
     8101 ctccgcctac taagaaaccc gagaggatcg gcggtgttgt ccaagggact tggactgctg
     8161 taaataaagg aacgaatcca aaatataaag cggaataggt aatcaatcct gaaacgaccg
     8221 gtgcgaaaat aaaaggaaca gccatcatcg ggttcatcac gatcggtgtg gaaaaaataa
     8281 ttgattcatt gatgttgaaa aaggctggta aaagagcaag atttcctaat tctctgtatt
     8341 tcttcgattt cgcaaaaacc gtcataaaaa atacagcccc taacgtcaat ccagcacccg
     8401 taaccgtcat gaactgatcg agaaattgct gagtaacgat atgtccgcca tttgccaccg
     8461 tcaactcttg tcctgaggct aagatttctg cattcgctaa tgaattcgct tgcaagacgg
     8521 gactaaccaa cccattgacc atcgcagatc catgaagacc aaataaccat aaaaacggaa
     8581 caaaaaaacc taataaaagc acaccaaaca acgtgtctat gaacgattga atgggaagct
     8641 ggacatatgt ccatactcct tgaacaacag tcattctgaa caactgttga aaaaccgctg
     8701 aaccgataag cgtaaaagtg actataacaa tgattggaat caatgaagta aaagactgcc
     8761 aaacattttc aggtatcttc tctctttgct tccacccttt cgcaagtctt actaaacgtg
     8821 catagcccca tccgatgatg agcccagttg taactgctcc tagtatccct tcagcacctg
     8881 tccagacagt atctatctga gtatttagtg gctgaataag cagtagataa gcagacaagg
     8941 ctgttatgcc gactggtaag cgatcgatgt cttcttcttt tgcataagcg tatgcaatgg
     9001 caaaaacgat ccaaaaggct atcacatcaa atgtagcctg gtatacttgt gtaaaataca
     9061 tagaaaatcc tgttttgtct atccactgag cgatgtaatc cacaggaaaa tgagcaaata
     9121 agaaaaacag cgagccaaca ataattattg ggatcgtgta agtcattcca ttacgcaaag
     9181 cagttaaggg tctaagattc acaacagatg ttatcattgg taaaaaggca cgatctaacc
     9241 actctttcat ttcttatctc cttcaacttc tatttttatc aatcagtttt cttaatttaa
     9301 ctatacccaa tgatcacgaa ccatgaaagg aatgcgcact gagcttttca aaaatcggat
     9361 tctttgacga atattcagca actgcttaca atggacagga ataaaaaagg aggtttttta
     9421 tgaaaattgc actcattgga gctactggcc atgcaggttc atttatttta gacgaagcat
     9481 tgtccagaga tttagacgtg acggcaatcg tgcgtcatcc agaaaaattg ccatcagatg
     9541 ttccgtttat acaaaaggat ttatttgagt tgacaactac tgatcttgca tcttttgatg
     9601 ttgtcgttga tgctttcaac gctcccaaag gaaaagaaga aatgcatcaa acttctttgt
     9661 cccatttgat tgagatgctt gaaggaaccg atacacgctt aattgtcgtt gggggtgcct
     9721 cttcgttatt cttagataca gaaaagacga ctcgtatgat tgaccaagta cctaaaaatg
     9781 cacccttcta tccaacagct ttcaatatgt acgaaggatt gttaaaattg aaacaatcta
     9841 aaaatctaca ttggacttat atcagtccag cttctttatt tgatccacat ggcaaacgta
     9901 caggtactta tttgttaagt gatgattatt tacaaagaaa cgctgctggc gacagtacga
     9961 tcagcatggc agattacgcg attgcattag tagatgagat actggatgag aaacatgaaa
    10021 agcagcacat cagtgtagtc agtcgataat acggttattt ttttaatatg ctaaaaaaat
    10081 aaaaatagaa gataaaacca accctgattg attttatctt ctgcttttta tatttttatt
    10141 gattgaactg tttaaatcga aaatagctca gttgcttcat ctggatctgt atcatagatt
    10201 tcaaaatcat gtccaacgcc aaaatctttt tctttcaaaa cattttccat tgttaaatga
    10261 gcaagttctt tcatattgtt ttccttgcta agatggccaa gatagattcg tttggtccga
    10321 ttaccgatca catcagtcat gacaagtgca ccgtcttcgt tggaaagatg tcctctatct
    10381 cctaaaatac gctgttttaa attccacgga taaggtccca tgcgtaacat ctcaagatca
    10441 tgattacttt ccatcaaata accatcggca ttttcaatga cacctcgcat ataatcactg
    10501 caatatccgg tgtccgtcaa catgacgaat gaccgatttt ctttatggaa acgataaaat
    10561 tgcggagccg ctgcgtcatg ggagacgccg aaactctcaa tatcgatatc gccgaatgtt
    10621 ctgactttcc ccatctcaaa tagatgtttt tgttccactg gtacatttcc aatcagtggt
    10681 tccatcgctt cccaagtctg ctgattggca aaaacatcca aatgatactt acgagccaag
    10741 acacccacgc catgtatatg atctcgatgt tcatgcgtca caagtattcc atctaattgg
    10801 tccggtgtcc gatcaatttg agccatcaag gaagtgattt ttttaccgct aagtcctgca
    10861 tcgaccaaaa gccgtttttt ttcactttcg atataaagtg aattacccga acttccactt
    10921 gctaggatac tgattttaaa agctggtttt tcttcagcca tttgactcct acttcccttc
    10981 ttactttgta aacttttttc attatactcg cttttttatt gatcttccac ttttggtaca
    11041 gtattgtttg tcacgatcgt attgctgaaa gcgttgacac tctcaatttg gaccacttta
    11101 tcgcttgttt cgatcgctac atgccaaaca ggaacataca catttttttc ccggactttc
    11161 agaatacagg aataagctag ctgacgccat aaaatttttg atcctcttgg tattttgtta
    11221 ttgatgtaca atgtattgat tgcttcctct tccgtataca gttccgtctt ttcgcgcagc
    11281 tgctcgatat cagataaatg cgtctgcatg tatttcgtga tgctataatc attatcgttt
    11341 ttttctaaag aaagaacgat ttttgctgta tcatcattga atgggatgcc ttcatactct
    11401 tggcttgctt ggatttctag tggttcttct tctaaatgag aaaagttttt cgtgtacaca
    11461 taatcattac cgaataaaat attgtctttg ttagataaaa aatcttccaa ggaactacta
    11521 attttatctg gatcgatcac gttcttttca gcatctgaac tggataaaga tttcgtcaaa
    11581 acatcaccgt ctaaaaacac accacttgcc agcaagccgc ttttaccagc cttgcgataa
    11641 ttcgctaatg aagtgctaag attggtctgc tccgcgctaa gataatagcc ttgcttgttc
    11701 tcagacgaaa tcttccccgt gtaagtgata tcgtcgctag ccagacgttg ttggattgat
    11761 tcagtctgat tagagcgaat gacattgttt tcttggtata ccgcgtcatg ataactgctg
    11821 aataaaaaca cattcaaccc taaaaaagcg acgaaaaata tccattcgat ttttttgaaa
    11881 tccaattaat tcgcctccaa tccaggtaat ttttccagaa ggtcgttagc tgaataccag
    11941 ttatctttat atttcacata ccattcaggt aagagatcaa cgacacgatt cgtttctttg
    12001 acattttgcc atgtatagcc aacgatcact gaaccaatct tgttgctatc tgctccctta
    12061 gcttttaact gctggatgat ttcattcgta cttgcaagtt ctacttcttc gtctgaaggt
    12121 atcggcactt gaatcgtatt caaactggtt tggatattca cttgcacaga accattcgtt
    12181 tcaccgccaa cttccacacc aatctgtcct ctgctgtctg tcccaaaaac cgggaagcct
    12241 tccacgaata tccgataatc gatcgtattg tcactgcggt caaaatatct gaggttccct
    12301 aaagaactgc ctaatttgct aatatagggg aaactttcag aaaatacact agcattttct
    12361 tttttctctg gcagctctcc acgaaaatca actacttgcg tttccgaatg gatagacatt
    12421 gtttcattcc caccgtaaaa aatcaattca ttgctttcat cattattttt cacgctatct
    12481 ggtttctgga aaaaagcatt tctaaaaagt gtatagggtt gctgtgacag gatataacta
    12541 tactttttca gtttgatcga atgtttcgta gcatattgcg tgtcgatcgt cgatggttct
    12601 gttgtcattt ctgtccattt tgtgtctttt gctgttaatt ctttattgat atctgtccaa
    12661 ttcaacgaaa tatttgcttc atatacgaga tggttcgaat aattcaaaaa tcggattttt
    12721 ttatttcctt gatcgaattg tattctagta aaatacatat tttcgctttc ttttgccaag
    12781 ttcgacacat ctaaatctaa atcaaatgct tccttgtatt ctcttagcaa aaaaggcgca
    12841 ttataggcca actcaaaacc agagttcaga tttttcacct gttcaaactg tgatttgtct
    12901 cctgaaacta cttcagaaag ctttccaaat cttgctttat cgatgatcaa ttgcaatcgg
    12961 tacacgagat tttcactgtt ggtttcttgg atcattcccg aatggtgcca tgtaacatga
    13021 agcggaagaa agacttcgga agtttttcga ttgctttgag actcgatcat ttgagtgttt
    13081 gtctcatcta cgttgattga actttttcct gctgggctca gccagattgc ataagagaag
    13141 tatatgctta acgcaaccat caaaatgagt cctatacgaa cgactttttc agagattctc
    13201 attcccacca ttcctcctca taaggttcat atggcagcga gatataaaaa gtcgaccctt
    13261 ttccttcctt gctctctgcc caaatagcgc ctcgatgcgc cttaatcact tctctagaaa
    13321 tagctaatcc aagtcctgtc ccaccttgtg ctcttgcacg tgctttatct actcgataga
    13381 accgctcgaa cactcggttc agatcttttt taggaatccc caatccttga tcggtgatac
    13441 ttaaaaccac gttattatgc gtttctaata agcgacaagt aatcgttccc ccatctggtg
    13501 aatacttgat cgcgttattc atgatattat cgactacttg gatgatttta tctgtatcta
    13561 cttcgaccca aagatctctt tgcgtaaatt cacgacggat cttataattt ttttcctgat
    13621 ttcccaccat catatcaaac cggtcaagaa caaaattcac taactcgttg aaattgacat
    13681 attctaattg aagctgggta ttacctgtat ccatgcgaga tagatttaag aggtcattga
    13741 tcattcgaat cattcggtct gtttcatcta gcgttacctt caaaaaattt ggtgctactt
    13801 cctcgtcttt ccacgcacct tcgctcaatg cttcgatata actacgcata cttgtcaacg
    13861 gtgtacgaag ttcatgggaa acattagaga cgaattcacg acgttcccgt tctgtttttt
    13921 cttgttctgt cacatcatgc aagacagcta ctaatccgct gataaaacct gattcgcgac
    13981 ggatcataga aaagtctact cgcaagatca tctgatcact ttccaatgta ctggttgaac
    14041 ggtcaagtac catttcgttt ggatcttcta ataatttccg caacgtatat tcttcttcga
    14101 tatctaaaag tgtcaaaatc gattgtccga ttgcttcctc gtttttgata tctagcaagg
    14161 aaacagccat atcattgatc gtaatgactt tacccctgcg atctgtcgca atgacgccgt
    14221 ctgtcatatg ggatagcacg ctatccaaac gattgcgttc agcttccatt gtatcttgag
    14281 cttcttcaat acgttcagct aactgattga aggtatcagc cagctgtcca agttcatctt
    14341 gtccatgcac tttgactttc cgactgtagt ctcctctagc gattcgaatg gcttgttctc
    14401 tcatttcacc gatcggctgt gtaatcgaac gagcaactaa aacagatacg atcattgaaa
    14461 taaatgccgc aattagtgag gcagtaaaga aaatgactgc tgtgttattg atttccgaat
    14521 atttttgttc gatattactt ttgacgtaaa gagccccgat aacggcatcg ccggtcgggg
    14581 acaggatcgg ttgaacattg atattcaccc gtttatcgtc gttatctaaa gcaacataac
    14641 gtttagtcgt gaaatcattg atatcaacat aatcattttt ctttcccaca gcgctttgtt
    14701 cattgacatc ggttgttcct cggatgatcc ctttttcgtc aacgacccgt atttcgatga
    14761 tatcgctagt cgcactgttt tcaataaatc ttttgatatt cgcatttacc tcttcatcat
    14821 ctgcattatc ttttcgattc aattccgggc tgattgttgt tgctaatgat tccaccgttt
    14881 gattcatatc tttaataaat gtattgatcg tggaacgttc taaaccacgt ataaagtagg
    14941 caccaataat ttcgatcgag atcaataaaa tcagaataaa ggtaatagcg atcttaaaat
    15001 tgactgatcg aaaaaagcgg acttttcttt tcatccaatt actcctgttc tgggttacgc
    15061 aaatagtaac cgacaccacg acgtgtcact aaataatttg gatggcttgg attatcttcg
    15121 atcttttcac gcaaacgacg tacagttaca tccactgttc gtacatctcc aaaataatca
    15181 taaccccaaa ccgtttgtaa taaatgttct cttgtcatca cttgtccaag gtgcttcgcc
    15241 aagtaaaaga gtagttcgaa ttcacgatgt gttaactcga ttgtttctcc tcgtttcgtc
    15301 accatgtaag cttctggatg gatcgtcaaa tcaccaatcg tcaattccgc aggtgctgcc
    15361 tcttctggtt ccttcgcagc cgtggcaccg cgacgaagat ttgctttgac acgtgcaact
    15421 aattctcggt tggaaaatgg cttggtcacg taatcatcgg cgcctaactc taagcctagg
    15481 actttatcaa tttcagaatc tttggctgtt accataatga tcggcatatc ataagttttg
    15541 cgtacctcac gagcaacttc taagccgtcc attttaggta gcatcaaatc aagtaaaatc
    15601 aaatcaggtt ctacctcagc aactttttcc aaggcttctt ccccatcata tgcagtataa
    15661 acatcatagc cttctttggc taaattgaat ttgacgatat ccgaaatcgg cttctcatca
    15721 tcgacaacta aaactttttt cataaagagc cacctcttat atattattgt cataccttct
    15781 cattataccg tatttctgct tttgtttcat ctttgcctat aaaacaaaag agaaaattaa
    15841 aatgaaagtg caaaatactt tattattttt tgttctaact tcaataaaaa aggaaaacac
    15901 tgattttcac ctcagtgttt cctttttttg atttatcctt ctaaaacttg tacaccgaca
    15961 cccaataatc ccggaccagt gtggactact aatgccggag aaatctggcc aaagtagatt
    16021 tggtttgctt gtgggaactc tcttttaagt ctcgcttcca tttcaattgc ttcttctttc
    16081 gcatccccat gggcaacagc taagttgaag acctttgcat taccgatttt ttctttgacg
    16141 taagcaaccg ttttatccaa acttttttta cgtcccctag cttttcctac tgtgtaataa
    16201 atcccttctt cattacatga gatgattggg ttaagcttta aagcggttcc tacaatagaa
    16261 gcaactaaac cgatccgtcc acctttttga agatattcca atgtcgcaac attaaagaaa
    16321 acttttgttc tttcgactaa ctcattcaga ttactgatca gttgatccca ttctactcct
    16381 tcttccagcc attttgctgc ttggatcgca gaaaaacctg caccaatacc aatatttttc
    16441 gtatctagta catatgcttc caattcttct tgctgttgtg caattaaacg aaccacatta
    16501 tatgtcccgc tcaatccact ggaaattgtt accgcaagta ccttttcata accgtctttt
    16561 ttgatttgct caaagatttc tgtgatcgac tcaccatccg gcaaagatgt accagggatt
    16621 tcctctggca aacgttgata gatctcttca gaggtaatgt caattttatc tgtatatacc
    16681 tgatctttat aaataatttt caatgggatc atatacatct cgtatttttt tatcaattct
    16741 tctggcacat ccgtacctga atctactaaa attgcgattt tattgttttt catttgtttt
    16801 ctcctctttt aaatattcgg tttctagaac aatcgttttt tccgcaagaa gtttcattgc
    16861 aaacgataaa gttgccgctc ttacagcaat atattctaca ggggttgcct ggtcgaattt
    16921 ttgcggatga gatttacctt gtgctaattg gctgaccatc cacacagctg cttcttgttc
    16981 atcgcaaaat agattatagg cttcacgaat tcctactgtt tttccttgga acaatatccc
    17041 ttctttgatt tcaggaatag tcaatacttg tttcaacgta gtgattgcaa gtaaaaatgc
    17101 tacgtgttct ttgttatatc tttttttaac tggtgctggt atcaaaccta gtttaacgta
    17161 attgtttacc atagaagagg taagcaatgg atgcttttct ccttgtatca caggtgaaag
    17221 ataacgatca actaacgttc tgacttggtc catataaagt tctaagtcag ggagttcttc
    17281 ccagtgaggc agacggaatg tttctagttc cttcccccac tccattaatt gctgacgcat
    17341 tttttccatc ataaccgctc cttttttcat ttcataaaca tgatatcaga cttatgataa
    17401 acattcaatc tagttgcttt aactaggtga tttgattagc gggattccat gaaaacaaaa
    17461 aacaagaagg ctaagccttc ttgtctttta tcgttaagaa caggagaccc gccggggaga
    17521 cggcgggaaa ggagtaaaaa atgaaaaaag tgttagggtt tgttctcttg caagaacttt
    17581 gtttgttggt atgcttatat aatagcgagc aaatgtgaat aatctatgaa tgatttccta
    17641 taaggaagta aagatttttc tgattttctt taaatgtagt cttgcatttt aaaattctta
    17701 gtgctactat tattaagtac tttttgtacg ggccgttagc tcagttggta gagcagctga
    17761 ctcttaatca gcgggtcgcg ggttcgagcc cctcacggcc cattgggtgc caaacccacg
    17821 tcaccagtac attcttggct acttaggtag tttcgaaaag agtgtacgtg gtggcatttt
    17881 ttatttttcg ggtatgaaat tcgggtatgc attttagtat tttatttttt aataacatcc
    17941 taatcagtca ataaacctgt agattatcac agtatgtact tcccctcca
//
LOCUS       DAZAOD010000053        17750 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000053 DAZAOD010000000
VERSION     DAZAOD010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.054"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            39..851
                     /locus_tag="ACHDPO_001781"
     CDS             39..851
                     /locus_tag="ACHDPO_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFN3369400.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            848..1648
                     /locus_tag="ACHDPO_001782"
     CDS             848..1648
                     /locus_tag="ACHDPO_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFN3369401.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1809..3077
                     /gene="rseP"
                     /locus_tag="ACHDPO_001783"
     CDS             1809..3077
                     /gene="rseP"
                     /locus_tag="ACHDPO_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFN3369402.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3145..4854
                     /locus_tag="ACHDPO_001784"
     CDS             3145..4854
                     /locus_tag="ACHDPO_001784"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFN3369403.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5066..9418
                     /locus_tag="ACHDPO_001785"
     CDS             5066..9418
                     /locus_tag="ACHDPO_001785"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFN3369404.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9562..10035
                     /gene="rimP"
                     /locus_tag="ACHDPO_001786"
     CDS             9562..10035
                     /gene="rimP"
                     /locus_tag="ACHDPO_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFN3369405.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10059..11234
                     /gene="nusA"
                     /locus_tag="ACHDPO_001787"
     CDS             10059..11234
                     /gene="nusA"
                     /locus_tag="ACHDPO_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFN3369406.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11256..11549
                     /locus_tag="ACHDPO_001788"
     CDS             11256..11549
                     /locus_tag="ACHDPO_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFN3369407.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11546..11857
                     /locus_tag="ACHDPO_001789"
     CDS             11546..11857
                     /locus_tag="ACHDPO_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFN3369408.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11870..14176
                     /gene="infB"
                     /locus_tag="ACHDPO_001790"
     CDS             11870..14176
                     /gene="infB"
                     /locus_tag="ACHDPO_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFN3369409.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14203..14550
                     /gene="rbfA"
                     /locus_tag="ACHDPO_001791"
     CDS             14203..14550
                     /gene="rbfA"
                     /locus_tag="ACHDPO_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFN3369410.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14658..15162)
                     /locus_tag="ACHDPO_001792"
                     /pseudo
     CDS             complement(14658..15162)
                     /locus_tag="ACHDPO_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15327..17690
                     /locus_tag="ACHDPO_001793"
     CDS             15327..17690
                     /locus_tag="ACHDPO_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFN3369411.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
BASE COUNT         6052 a         3148 c         3912 g         4638 t
ORIGIN      
        1 aagatagtgg gaatctttta agtataggag gaaaaagaat gttacgtttt tttccgcaaa
       61 aaaacaaata tattcaagaa aaaagcgaat ttcaatttaa taccgatgga ccaattcctc
      121 agcacattgc catcatcatg gacggcaatg gtcgttgggc gcaaaaccgt cgtttgccac
      181 gagttgctgg ccataaagaa ggcatggaaa cagtaaagaa agtcacaaaa aaagcatcaa
      241 ggcttggagt gaaagtgttg acgctttatg ccttttcgac tgaaaactgg aagcgaccaa
      301 aagatgaagt aagttttctc atgcaactac ctgtcgactt ctttgatacg ttcgtaccag
      361 aattgattaa agaaaatgtc aaagttcatg tcatgggtta tgaaaacgta ttgccagaac
      421 atacgcaaga tgctgtaaga cgtgcaattg agcaaacaaa aaacaatact ggaatggtat
      481 tgaattttgc tttgaattat ggaagtagag cagagatcgt gactgctgtc caagaaattg
      541 ccgaagaagt agcaaaagga gaaatacacg cagaagaaat cgatgatgaa ttgattgcta
      601 agcatttaat gacaggtttc ttgcctaaag agttacaaga tcctgagctg atgatccgta
      661 caagtggaga agagcgaatt agtaattttc tgttatggca gatcgcatat agtgagctgt
      721 attttacaaa agcgctttgg cctgattttg atggtgcgca tcttgaagaa gcaatcgcct
      781 cttatcaaaa tcgagaccgt cgattcggcg gtgtaaaaaa aacagaagat gagaaagggg
      841 atcagtcatg aaacaacgtg tgatcacagc agctgtggcg ctagtcttgt ttattccgat
      901 tatatggatc ggaggcatag cggttgagct tacagcagca atcttagcgg tagtaggagt
      961 ttacgagctg ttccggatga aaggattgac actcttaagt tttgaaggag ttttatccgc
     1021 cgttggtgca gtgttacttg ttttgccaaa agaaagatgg tttttctttc ttccagagaa
     1081 tgtaagtaca tttatgttat tttatcttat agttatgatt cttttaggaa catcagttat
     1141 ttctaaaaat acgtatacga ttgatgaagc aggttttcct gtgcttgtca gcttgtatgt
     1201 gggaataggt ttccagaatt ttgtcaatgc acgaacagaa agcttggctg ttttgatatt
     1261 tggtctattt attgtttggg caactgatat cggagcatat atggttggtc gacgttatgg
     1321 tcagcataag ttaagtcctg atatttcgcc caacaaaacg attgaaggtg cgctcggtgg
     1381 tatcggtagt gctgttgtag tcgcatttct ttatttattg ctatacccag caaaagaact
     1441 attcaatcat ggtatgtttg tcatgcttct gatgacgatt attttttcag cagtcggaca
     1501 atttggtgat ttggtcgaat ctgcaatcaa acgtcattat gatgtgaaag actcgggaaa
     1561 tatcttacca ggccatggtg gaatcttaga ccgtttcgac agtttgctgt ttgtatttcc
     1621 tatcatgcat ttatttggca ttatttagta agtatacctg cgtttctttg tgaatttcat
     1681 aaaagacgca ggtttttatt tttcattata ttgatactat tggtgtcttt ggtatactat
     1741 ggtaaaatta tagtgtttta tcgttgtttt ataaaaaaca caaaaaacaa gtaaaggaga
     1801 aaaaagctat gaaaacgatt ctgacattta tcatcgtttt tggtatatta gtgattgttc
     1861 atgagtttgg tcatttcttc tttgcgaaac gatcaggaat cctcgtccgc gaatttgcta
     1921 tcggtatggg tccgaaaatt tatgggcatc aagcaaaaga cgggacaaca tatacgcttc
     1981 gcctattacc tattggcggt tatgttcgaa tggcaggcaa tggggatgat gaaacagaaa
     2041 tggcaccagg aatgcctctt tctcttttac taaattctga cggcatcgta gagaagataa
     2101 atttaagtaa gaaaatccaa ttgacaaatg ctatcccgat ggaattgagc cgttatgatt
     2161 tagaagatga gctgactatc actggttatg tgaatggaga cgaaacagaa gtagtaacct
     2221 accctgttga tcacgatgcg acgattattg aaaacgacgg aacagaaatc agaattgcgc
     2281 caaaagacgt acagttccaa tcggctaaat tgtggcagcg tatgctgacc aactttgctg
     2341 gacccatgaa taactttatt ttggcaatcg tgttattcat cattctggca tttatgcaag
     2401 gtggtgttca agtgacgaac actaatcgcg taggagagat catgcctaat ggagctgcgg
     2461 cagaagcagg cttaaaagaa aatgatgagg tagtcagtgt ggacggaaaa gaaatccatt
     2521 catggaatga tctgacaaca gtcattacga aaaatccagg taaaacatta gactttaaga
     2581 tcgaacgaga aggtcaggtg caatctgtcg acgtgacacc gaaatctgta gagtcaaatg
     2641 gcgaaaaagt tggccaactt ggtataaaag ccccaatgaa tacaggtttt atggataaga
     2701 tcattggagg gacgcgtcaa gctttcagcg gttcattgga aattttcaaa gccttaggat
     2761 cactatttac aggtttcagt ttagataaat taggcggacc tgtcatgatg taccaattgt
     2821 cttcagaagc agcaaatcaa ggtgtaacaa ctgttattag tttgatggcg cttctttcaa
     2881 tgaatctcgg aatcgtcaat ctgcttccga ttcctgcctt agatggcggg aaattagtct
     2941 tgaatatttt tgaagggatt cgcgggaaac cattaagtca agaaaaagaa ggaatattga
     3001 cattagctgg ctttggattt ttaatgttgt tgatggtgct agttacatgg aacgatattc
     3061 aacgattctt tttctagaaa aagttgacaa atagggtata ataacaaacg ataactattt
     3121 tgaggaaata aaggagtata tagaatgaga caatcaaaaa tgttgattcc aacattacgc
     3181 gaagttccaa atgatgcaga agtattaagc catcaaatct tgctaagagc tggatatatc
     3241 cgccaagtat cagcgggtat ttattcatat ctgccattag caaatcgtgt attggaaaaa
     3301 ctgaaacgca ttatgcggga agaatttgaa aaaatcggag cggtagaaat gctgatgcct
     3361 gccatcttgc cagcagaact ttgggaagaa tccgggcgtt acgaaacata tggaccaaac
     3421 ttgtatcgtt tcaaagaccg caatgatcga aaaatgatcc ttggaccaac tcacgaagaa
     3481 acttttactg atttgatgcg taatgaaatc aattcatata agaaattacc tttaaatctt
     3541 tatcaaatcc aacctaaata tcgtgacgaa aaacgacctc gcttcggttt gcttcgcgga
     3601 agagagttta tcatgaaaga tgcatattct ttccatgcaa cggaagaaag tttggacgag
     3661 acatataaag attacgaaaa agcctatacc gaagtattca agcgttgtgg cttagaattt
     3721 cgctcgatca tcggagacgg cggcgcaatg ggcgggaaag actcaaagga attcatggcg
     3781 atctcagaaa tcggggagga tacgatctgt tattcgactg aaagtgatta tgctgcaaac
     3841 ttggagatgg ctacaagcta ctatgtatca aaaaaatcgc atgaaacaca gcttgaattg
     3901 gagaaagtag ctacacctaa cgtaaaatca attgacgaag tagcagattt cttttctgtt
     3961 gaacctcaaa aaatcatcaa gtctgtattg ttcattgcgg atgaacaacc tgtccttgtt
     4021 ttggtacgtg gagaccatga agtcaatgac gtaaaactga aaaacttttt atctgctgac
     4081 tttttagaag aagcaacaga agaagaagca caaaaatatc taggtgctga gtttggttct
     4141 gtcggaccag tcggtgtttc agatgacgta aaagtatatg cagaccgtta tgtccaagat
     4201 ttagcgaatg ccattactgg agcgaacgaa acaggattcc actataaaaa tgtgaatcca
     4261 aaacgcgatt tcactgtgct ttcttatgaa gatcttcgtt ttgtacaaga aggagatcct
     4321 tcaccagaca acaacggtgt tcttgccttt actcgaggaa tcgaaatcgg acatatattc
     4381 aaaatcggca ctcgttacag tgaatctatg ggagcaactg tactagacga aaatggacga
     4441 gaaaaatttg tgattatggg ctgttatggt atcggtgtaa gtcgtttatt atcagcaatc
     4501 gtagaacaac attcagatga acaaggaatc aattggccaa aaggaattgc gccatttgat
     4561 ctgcatatcg tccaaatgaa tctaaaagac gaataccaaa caagcctgac gaatgaacta
     4621 gaagaagcga tgacaaaagc tggctatgaa gtactggttg atgacagaaa tgaacgcgca
     4681 ggagtgaaat tcgcggattc tgatttgatt ggctgtccaa tcagaatcac tgtcggtaaa
     4741 aaagcagtgg atggaatcgt agaagtgaaa atcaagaaaa ctggcgaaat ggttgaagta
     4801 cgtaaagaag aattggcgaa tactttacca atcctcttga accaaggcga ataataagcg
     4861 ttaaaacaca gaaaataaaa atagctgaat cagctgtttt tgacaatctg atgattcgct
     4921 tttaaaattg gaactgcgat ttgaatcgca gttccaattt tttaatgtaa aactcagaaa
     4981 aaacgagtat actaaaaggt actgaaaaag aagaggataa gatgcgatca attgcattgt
     5041 ttctcatcag aaagggcgta tatctttgtc agaaaaacga gatttatttg aaaaactgtt
     5101 ggaacaaatc caactagagg aagcagaaaa aaatcatcca ctgcttactg ctggtgaaat
     5161 ggatagtgta gtggtccatc gtaaatcgcg tttatgggaa tttacgctac atttttccaa
     5221 aattttgcct attatgctat atcggtcatt gactcagcat ctgactatcg cttttaaaga
     5281 tattgcacaa gtcaaactga atatcttagc agatgaccag acattcgatg aacagctctt
     5341 gcaagattac tgggcccaag ctttggaaaa tcagcaatgc gatacaccac tagcacagca
     5401 agtattgaaa acgcaggtac ctgtgataaa agatcgtaaa gtcatcttgc caatcgacag
     5461 tacaggagct atttcttatt tgaagcaaca atacttgcca ttagtagaag agttgttcgt
     5521 cagttacgga ttcccaaaat ttcgtatcga accagaagtg gatgagcagc aagcggaacg
     5581 tgtattgaaa ctttttgaag aacgcaaaca agaacaggca gaagccttta tgaagcaagc
     5641 agctgaaagt ctagttgtcc acgaacaaaa gaaaaaggaa agaaaagagc aatcgccagc
     5701 tcttgaagga cccatccagc taggacgaaa tattccagcc gatgaaccaa cgacaccaat
     5761 gatcagtatc gttgaagaag aacgaagagt cacacttgag gggtacgtat tcgacaaaga
     5821 agtcagagaa ctacgttcaa aacgcaagat cttgactttg aaaatcacag attatacttc
     5881 atcatttatc gtcaaaaaat tctcgaacgg cgaaaaagat gaacaagtat ttgatgcgat
     5941 cagtgtcggt agctggttaa aggtacgagg aagtattcaa gaagatacgt ttgtccgtga
     6001 tttggtcatg aatgcgcaag atatcataga agtcaaacat acacctcgca aagattatgc
     6061 tcctgaaggg gaaaaacgag tagagcttca tgttcatagc aatatgagta cgatggatgc
     6121 aacaaacagc atctctgatc ttgtggcaca agcaggaaaa tggggacacc gagctatcgc
     6181 cattacagac catggtggtg cgcaagcctt tccggaagca catagtgctg gaaaaaaagc
     6241 aggtgtgaaa atcttatacg gcgtggaagc gaatgtcgta gatgatggtg tcccaattgc
     6301 ttataatgat gcacatgaag cattgagtga agccacatac gtcgtatttg acgtggaaac
     6361 gacaggattg tctgcagtat atgacacgat catcgagcta gccgcagtca aaatgtataa
     6421 aggaaatgtg atcgaaagct ttgatgaatt tatcgatcca ggacatccat tgtcacgaac
     6481 aacggtagat ctgactggta tcacggatga aatggttcga gggtcaaagt cggaagaaga
     6541 agtattgcgg atgttccttg aattttcaaa agatacaatt ttggtagccc acaacgcggc
     6601 ttttgatatg gggttcttga atactagcta cgcaaggtat ggtattcctg aagcggccaa
     6661 tccagtcatt gatacgttgg aattagctag atatctgtat cctcaattca aacgtttcgg
     6721 attaggtgtg ttatctaaaa agtttggtgt tagcttggaa cagcatcacc gagcaatcta
     6781 tgatgctgaa gcaactggtc acttagcatg gatctttgtg aaagaggcaa tggacaatca
     6841 taacatgctt tatcatgatc agctaaatga gcatatcgga gaaggagatt cttacaaaag
     6901 ggctcgacct ttccatgtaa cgattttagc aaaaaatcag gcaggactga aagatttgtt
     6961 caaactgatt tcaatgtcga atgtcgaata cttcgaacgc gtcccacgaa taccacgctc
     7021 ccaattgaaa aagatgcgtg aaaatctatt gatcggctca gcttgtgata agggagaaat
     7081 attcgaagcc atgatgcaaa aaggggtaga agaggcaaga aaccgagcaa aattctatga
     7141 ttatattgaa gttatgccaa aagcggtcta tgcgcctttg atcgagcaag aattggtaaa
     7201 aaatgaacat gatttggaag aaattatcca aaatttggta gaaatcggaa aaagtttgga
     7261 taaaatcgtt gttgcaacag gtaatgtaca ttatctgaac gaagaagatg ccatttaccg
     7321 aaaaattttg atcaattcta tgggcggagc gaatccgttg aatcgtcata gtttgccgga
     7381 tgtccatttc cgaacaaccg atgagatgct aactgcattt cactttttag gggaagaaac
     7441 agcgaaagag atcgtagtag aaaatacgaa taaaatcgca gatatctgcg aagaagtgat
     7501 tccagtcaaa gatgaacttt atacaccgaa gattccaggt tcagaagatg aaatatcaga
     7561 attgagttac acaaaagcaa aacaaatgta cggagatccg ttacctgaga tcattcaaaa
     7621 acgattagaa aaagagttga attctattaa tggtaatggc ttctcggtta tttatctgat
     7681 cgcccaaaaa ctagtgcata aaagtaatga agatggctat ctagtaggtt cacgtggctc
     7741 tgttggctct agctttgttg cgacgatgac aggaatcact gaagttaatc cattagcccc
     7801 tcattattat tgtccagagt gccaatattc cgagtttttt gaagatggta cgtatggttc
     7861 tggatttgac atgccagaaa aacaatgtcc aaaatgtggt gcacgcttaa acaaagacgg
     7921 tcatgatatt ccatttgaga catttttagg attccatgga gacaaagtgc ccgatattga
     7981 tttgaacttc tcaggtgatt atcaagcaga agcccataac tatacgaaag tattgtttgg
     8041 cgaagactat gtttaccgtg ccggaacgat tggtacagtc gccgacaaaa cagcatatgg
     8101 ctatgtaaaa ggatacgaaa gggacaataa tctgcagttt cgaagtgcag aagtcgacag
     8161 attagcaaaa ggcgctactg gagtcaaacg gacaaccggc cagcatccag gggggatcat
     8221 cgttattccc gattatatgg atgtctatga ttttacgccg atccaatatc cagcagacga
     8281 tcaaaattca gaatggaaaa cgactcattt tgatttccac tcgattcacg ataatgtatt
     8341 gaaattagat attctagggc atgatgaccc aactgttatt cggatgcttc aagatttatc
     8401 agggatcgac ccacaaacga tccctacgga tgacccggaa gtgatgcgga tatttgccgg
     8461 tcctgaagta cttggagtaa gtcaggaaca aatttattcc aaaacaggga cattaggtat
     8521 tccagaattc ggcactcgtt ttgttcgagg gatgttagaa gaaacgcatc ctacaacttt
     8581 tgcagaacta ctgcaaattt ccggactatc tcatggtaca gacgtatggt taggaaatgc
     8641 ggaagaattg attcgacgag gagatgcgac actggcggaa gtaatcggct gtcgtgatga
     8701 tattatggtt tatttgatcc atgctggatt agatagcggg atggcattta aaatcatgga
     8761 aactgttcgt aaaggacaat ggaacaagat ccctgatgaa ttgcgagaaa cctatctatc
     8821 ggcgatgaaa gaaaataatg tgcccgactg gtatatcgat tcttgttcaa aaatcaaata
     8881 tatgtttccg aaagcccatg ctgcagctta cgtattgatg gctcttcgtg tcgcttattt
     8941 caaggtttat ttccctattt tgtattactg tgcatacttt tctgtacgtg cagacgactt
     9001 tgatctagtc tccatgtgca aaggaaaaga tgctgtgaaa caagcaatga aagaaatcac
     9061 ggacaaggga ttagatgctt ccgtaaaaga aaagaatcaa ctgacagtgc tggagttagc
     9121 caatgaaatg ctggaacgag gattcaaatt tggaatgatt gatttgtata aatcggatgc
     9181 cgttaacttt gttattgaag gtgatacgtt gatcgcacca tttagagctg tcccaagttt
     9241 gggaaccaac gtggcgaaac aaatcgttga agcaagaaaa gacggtccat ttttatccaa
     9301 agaagatctt gccacccgcg gtaaagtttc aaaaacattg atcgaatata tgaacgacaa
     9361 tggcgtattg aaagatctac cagatgaaaa tcaattatcg ttattcgata tgctataagc
     9421 atctgttttc ctgtctgctt gtaattttaa gcagagtatg gtatagttct tataggtaat
     9481 gatactaact gtgagtgagc ggatttttcg ctcactcttt ttaatggaat tacgcactta
     9541 atttttaagg aggcgaaact tttgagtagc gtcgttgaaa cagtcacaga aatggtgaca
     9601 ccgattttag atgaacaaaa ttttgaactt gtcgaagtcg aatttgtaaa agaaggaaaa
     9661 agctggttct tacgagtatt tattgacaaa gaaggcggta tcgatatcga agaatgcgcc
     9721 tttgtcagtg agaaactgag tgaaaaactt gatgcagcag atccagatcc gattcctcaa
     9781 gcttatttcc tggaggtatc ctccccggga gcagagcggc cattgaaaaa agaaagcgac
     9841 tatgaaaagg cacttggtga ttatgtccat gtctccttat accaaccagt agatggcgaa
     9901 aaacaatatg aaggatttct tcaatcattt gatgctgaac agcttacatt gaaaatacgc
     9961 ataaaaacac gagaaaaaga attgactttt gaccgaaaaa atattgcaaa agctcgctta
    10021 gctatccaat tttaatcacg gagaggaatc agaaaaaaat gagtaaagaa atgttaaatg
    10081 cgttagacgc tttagaagct gaaaaaggga tctcaaaaga aatcgtgatc gatgctttag
    10141 aagcagcatt ggtttctgca tacaaacgtc actatggcca agcacaaaac gtcgaagtgg
    10201 aatttgatca gaaaaaagga aagatccatg tctatgcggt aaaagaagta acggaagaag
    10261 tgatggattc acagttggaa gtctcattga aagatgcact tttaatcaat ccagcatatg
    10321 agatcggtga tacgatccgt tttgaagtaa caccaaaaga ttttggacgg atcgctgcgc
    10381 aaacggctaa acaagttatt ttacagcgtg tacgtgaagc agaaagaacg attatttata
    10441 acgaattcag tgcttatgaa aaagacatca tgcaaggaat cgtcgaacgc caggataaac
    10501 gttatattta tgtcaatctt ggtaaaattg aggcagttct ttctaaacaa gatcaaatgc
    10561 caaatgaatt ttatcaacca catgatcgaa tcaaagttta tgtttcccga gtagaaaata
    10621 cgtctaaagg tccgcaagta tttgttagcc gcagccatcc agacctattg cgtcgcttat
    10681 ttgaacaaga agtaccagaa gtctatgatg gaatcgttga aattgtcagc atcgcccgtg
    10741 aagctggcga tcgttcaaaa gtggcagttc gctcaaatga tccaaatatc gatgcagtcg
    10801 gtacatgtgt cgggccaaag ggacaacgag ttcaagcaat cgtcaatgaa ttaaaaggcg
    10861 aaaacatgga tatcgtcgaa tggaatgaag atccagctgt attcatcgca aatgcattga
    10921 atcctgcaca agtcatggat gtgatcttcg atgagacaaa tccaaaggcc tgcacagttg
    10981 tcgttccaga ctaccaatta tcgctagcaa tcggtaaacg cggacaaaat gcacgtttag
    11041 ctgctaaatt gactaaccat aaaatcgata tcaaatcaga atctgacatg acggaatttt
    11101 atgaaaatca agaacaacaa aaagaaacag aagaactgca tgatgaagca atcgttcagt
    11161 cagatttaac agacgatgaa tatgaaacaa ttgcattcaa caatgaaacg gtcgaagaaa
    11221 aaccagaagc ttaactttag taaggaggca aagagatgaa acaaaggaaa attcctttac
    11281 gcaaatccgt ggtttcaggt gaaatgaaac ctaaaaaaga gatggtccga atcacccgtt
    11341 caaaagaagg ggaagtatcg atcgatccaa ctggaaaaat gcctggacga ggagcgtatg
    11401 tctcacttga gccggaagaa gtacaacaag cttgggataa aaaaattctc gatcgagtac
    11461 tcgaaacaac attaacagat gagttttatc aagaacttct tgactatgtc actcaccaaa
    11521 aagcacgtaa agagttattt ggaaaatgaa tacagttaat cggcaaaaag ccatgaatct
    11581 catcggtcta gcgatgcgcg cgggaaaact aatcacgggt gaagaactga ccattgctga
    11641 aatccgcaaa caaaaagcaa aattggtgtt tgtggcaacc gatgcaagtg agaatacaag
    11701 aaaaaagata aaagataaga gttcatatta tgaagttcct tgctttgagc tattttctga
    11761 agcagaaatc acgcagatga tcggaaaacc tcgcaaggta ttcggaataa tggatgccgg
    11821 atttgcgaag aagaccaagg agctaattga aggttaggaa ggtgattgca tgggcaacaa
    11881 aagaatctat gaattagcaa aagaactcaa aaaatctagt aaagacgtcg tggaaaaagc
    11941 acaacaactt ggcatcgatg tgaaaaacca tatgggtgcg attactagca gtgatgagaa
    12001 gaaattgcaa caagcgttca aaaacccaag cacgaaacaa caagctgcac aacaagcaag
    12061 cagaaaacca gccaatcaac agccgaacga tcaacgtaaa aaagaaacaa cgaacaatca
    12121 acaaaaaaat aaaaataacc gcagttatca agatcgcggt caagggagcg gtcaagtgaa
    12181 tcaaggaaaa aaaccaacaa caaaccaaaa taatacggga aataccagca gccaaaatcg
    12241 tcaaggaacg agccaaggcg gcaatcaaaa ccgtactaac aataacaaca aaccaaacaa
    12301 taacaatcgc ggcaaattta ataataataa ccgtaatcgt tataataaaa aaggtaaaaa
    12361 aggcaaacag caacaatcaa ctaaaccagc tgtaccacca cgcaaattcc gtgaattgcc
    12421 agatgtatta gagtatactg aaggtatgaa cgtagcagat attgcgaaaa aaattcatcg
    12481 tgagccagca gaaatcatta aaaaattatt tatgcttggt gtcatggtca atcaaaacca
    12541 agcactggat aaagatacga ttgaactgtt agcgacggac tatggcatgg aaccacaaga
    12601 aaaagtccaa gttgacattg ctgatatcga taaattcttc gaggcagaag aagtcgatcc
    12661 agataaatta gtctcacgtc cgccagtagt aacgattatg ggacacgtag accacgggaa
    12721 aacaacctta ttggatacat tgcgccattc acgtgtaaca agcggcgaag ccggcggaat
    12781 cacacagcat atcggtgcct accagatcga tattgatggt aaaccaatca ctttcttgga
    12841 tacaccagga catgcggcct ttacaagtat gcgtgcacgt ggagcaagta tcacagatat
    12901 cacgatctta gttgttgctg cagatgatgg cgtcatgcca caaacagttg aagcaatcaa
    12961 ccatgccaaa gctgcaggcg ttccaatcat cgtcgctgta aataaaattg ataaaccagg
    13021 tgcaaatcct cagcatgtta tgcaagaatt aagtgagtat gaattaattc ctgaagcatg
    13081 gggtggagaa acgatttttg ttgagatctc agcgaaattc ggccaaaaca tcgaagaatt
    13141 gctggaaatg atcctgttag tcgcagaagt agaagattta aaagcagatc caacacaacg
    13201 cgcaatcgga acagtgatcg aagcacgtct tgataaaggt aaaggtcctg tgtcaacctt
    13261 acttgtccaa gaaggaacac ttcacgttgg tgacccaatc gttgtcggta atacttacgg
    13321 acgtgtccgt gtaatgacaa acgatcttgg ccgtcgcgat aaagaagcag gacctgcaac
    13381 gccagtagaa atcactggct tgaatgatgt acctcaagca ggtgaccgtt tcgtagtctt
    13441 cgaagacgaa aagacagcac gtgcagcggg tgaagaacgc gcaaaacgtg cattattgga
    13501 aaaccgtgct gccacaagcc gtgtgacttt ggacaactta tttgaaagcc tgaaagaagg
    13561 cgaattgaaa gaagttaacg taatcatcaa agcagatgta caaggttcag cagaagcact
    13621 ggctgcatca ttgaagaaga ttgatgtgga aggtgtccgt gtaaaaatcg tccattcagc
    13681 tgtcggagca atcaatgaaa gtgatgtaac cttagcagca gccagcaacg ctattatcat
    13741 cggtttcaac gttcgtccta caccgcaggc aaaagtgcaa gctgatactg aagaagtcga
    13801 tattcgtctt caccgtatca tctataaagc catcgaagaa atcgaaactg cgatgaaagg
    13861 gatgctagac cctgaatttg aagaaaaaat caccggtcaa atgatcgttc gtgaaacctt
    13921 caaagtttct aaagttggta cgattgcagg tgcctatgta acagaaggat atattcgtag
    13981 agatagcggt gtccgtgtaa tccgtgacgg aatcgtaatc tatgaaggcc aacttgcaag
    14041 tctgaaacga ttcaaagatg acgtgaaaga agtcaaaatg ggttatgaat gtggtgcgat
    14101 gattgaaaaa ttcaatgaca tcaaagtaga tgacgtaatt gaaggattta tcatggaaga
    14161 agtcaaaaat gactaaaaac tgataaaagg aggccaatca ttatggctaa ctaccgtgat
    14221 cgccgagtcg gtcaagaaat cttaaaagaa gtcaatgata ttttgcgcaa aaaggtccgt
    14281 gaccctcgtg tggagaacgt aacgatcaca gatgtgaaag ttacggggga cttacagcaa
    14341 gcaacgatct attacagcat tttatctgac ttagcatcag ataagaaaaa agcacaagat
    14401 ggattgaata aagcatcagg attgattcgt cgagagttag ggcacaatct aagtatttat
    14461 aagacacctg aattgttctt tgaacttgat gaatcagttg tctatgggaa ccatatcgat
    14521 gaattgcttc gcgacttgaa caaagactaa tcaaaaaatc ccgcaaatcc tgtgaaatca
    14581 ggggttgcgg gatttttttg ttttcattaa gacgtattac ctaagagttc catgacttta
    14641 gtctggtagc gtgtcagcta accaaaaaag agaaaaagaa aagtaaaaaa ttcgactttc
    14701 ttttttctat agtatataaa tttttgcata tagataaaga tcaagatacc gataacggaa
    14761 gctagattgt aatctatttt agtgacagtc aggtatagcc aagtaactag aagatcagtg
    14821 gaacctgcac cataaaagtt tgagtttgtc ggtccgttga cagttaaaag aaaaatcacg
    14881 ttgaagttat tgatatttcc gattacgccg cttcgatttg gtcacgatcc aaattttgga
    14941 taatccctgt agaaattagc atagtagctg ggataccaat tcacatattg acaaagataa
    15001 cagagacttt tacataaaac ggatcaatca ggaaaggaat tgctcgatcc agccccagtt
    15061 ttccaacaat gtgttaactg gcctagcgtc attcagcaaa ttatgcatga tgaggagcga
    15121 aatgaactgc ggaacagcca ttgtgataac gacaagtttt ttggatcaat gtaaaaaacg
    15181 tcagcgaaag gaaaaatttc gtggtttttt atacctgttc atttggctag atataaaatc
    15241 caaacaaatg aacagaagtg cttattaggt ttcaattggg agtatctgcg ctagaataag
    15301 agtaataatg aaaaggagtg ttatgtatgg attattctag taaagaatac tttgataaaa
    15361 tgacggcttg gtggcgtgct gctaattatc tttctgttgg gcaactttat cttaaagata
    15421 accccttact gagacgtaca ctgaaaccag aagatgtcaa aaaacatcca atcggtcatt
    15481 ggggaacgat tcctggccaa aattttattt atgtccattt gaaccgagtc atcaataaat
    15541 atgatttgaa catgttttat atcgaagggc caggacacgg cggacaagtc atggtatcga
    15601 atgcttattt agatggaagt tacacagaga tctatccaga agtaacggaa gatgagacag
    15661 gaatgcaaaa attattcaag cgattttcat ttcctggagg cattgcttct catgcagcac
    15721 cagaaacacc aggttctatc catgaaggcg gagagcttgg atactctctt tcacatgcag
    15781 tcggagctgt attagacaat cctgaagtaa tctctgctgt cgtgattggt gatggtgaag
    15841 cagaaaccgg tcctttagct ggaagctggt tctcaaatgt ctttatcaat ccagtgatag
    15901 atggagctgt tttaccgatc cttcatttaa atggtgcaaa aatagccaac ccaacgatct
    15961 tggcacgtaa atcagatgga gaattagcaa attactttaa cggacttggc tgggagcctt
    16021 tctttattga aggaaatgat ccagaaaaat taaatcctgt tatggctgaa aaaatggatc
    16081 aagcaatcga gaaaatcaaa tccatccaaa aagaagctcg cctgaagaca gcaacagatg
    16141 tcgtgatgcc aaaatggcca gtattgatcg tacgcacacc aaaaggatgg accggtccaa
    16201 aagaatggga cggggaacca attgaaggaa ccttccgagc acaccaagta ccgattcctg
    16261 tagatcaaga acatatggat catgcagatg ctttactccg ttggctgaaa tcctatgaac
    16321 cagaaaaatt atttgatgca caaggacgta ttttagaaga aatcagagaa attgcgccta
    16381 ctggtgacca aagaatggca aaaaatccta tcaccaatgg tggaatcgat ccaagaccgc
    16441 ttattatgcc agattggaaa aaatatactt tgcaatttga aaaaccaggc tccgttaaag
    16501 cagaagatat gaccgaactt ggtaaattcg ttcgcgagat cattgagaaa aatccagaaa
    16561 atttccgtat atttggacca gatgaaacaa aatcaaaccg attgaatcaa gttttcaaaa
    16621 cgacaaatcg ccaatggatg gaaaaaatcg aaccagaaaa tgatgaatgg ctttcgccat
    16681 ctggtcgcgt catcgacagt caattatcgg aacaccaaga tgaagggttc ttagaagggt
    16741 acgttctgac tggacggcat ggtttttttg caagttacga atcattcttg cgagtggttg
    16801 actctatgtt gactcagcac ttcaaatgga tacggaaatc acatgacctt tcttggcgaa
    16861 aagattatcc ttcgctgaat ctcattgcaa gctcaacagt cttccagcaa gatcacaatg
    16921 gatatagcca ccaagatcca ggaatattga cacatttggc agaaaagaag gcggagttca
    16981 tccgtgaata tctgcctgcg gatgcaaata cattgctcgc agtcatggat aaagcattcc
    17041 gctcgtcaga aaaaatcaat ttgatcatct cttccaaaca tccgcgtgct caattttact
    17101 cagcagaaga agcagccgtc ttagtgaatg aaggcttgaa aatcattgat tgggcttcga
    17161 cagcaaaaga ggaggaacct gaattggtca ttgctgctgc aggaacggaa tctaacttag
    17221 aagcattagc agctgtaact ttgctgctgg aagaattccc aaaactaaaa attcggttca
    17281 tcaatgtcgt agatttattg aaattacgtc atccaagtca agatccgcgt gggttgagcg
    17341 atgaagaatt tgatcaatat tttacaaaag acaaaccgat cttatttgct ttccacggtt
    17401 atgaaacatt ggtccgcacg attttctttg atcgtcataa ccatcattta atgattcatg
    17461 gctacaaaga aaatggagat atcacgacac catttgacat gcgtgtagta aatgaacttg
    17521 atcgttatca tttggcaaaa gacgcagctt taaaaatcaa aggaagtcaa gcagaagatt
    17581 ttgcggaaaa aatggatcag aaattacaag aacatcaaaa ctatattcgt gaaaatggta
    17641 ttgatctgcc agaagtattg gattggaaat ggaaaaatct tgaccaataa aatgataaaa
    17701 tcgatcccgc aaaacagaat tttttacatt gtattatttg tcaaattaag
//
LOCUS       DAZAOD010000054        17607 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000054 DAZAOD010000000
VERSION     DAZAOD010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.055"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(176..2173)
                     /gene="tkt"
                     /locus_tag="ACHDPO_001794"
     CDS             complement(176..2173)
                     /gene="tkt"
                     /locus_tag="ACHDPO_001794"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFN3369412.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2275..2526)
                     /locus_tag="ACHDPO_001795"
     CDS             complement(2275..2526)
                     /locus_tag="ACHDPO_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFN3369413.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2673..3296
                     /gene="lexA"
                     /locus_tag="ACHDPO_001796"
     CDS             2673..3296
                     /gene="lexA"
                     /locus_tag="ACHDPO_001796"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFN3369414.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3476..3694
                     /locus_tag="ACHDPO_001797"
     CDS             3476..3694
                     /locus_tag="ACHDPO_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369415.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3983..4495)
                     /locus_tag="ACHDPO_001798"
     CDS             complement(3983..4495)
                     /locus_tag="ACHDPO_001798"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFN3369416.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4509..6806)
                     /gene="recJ"
                     /locus_tag="ACHDPO_001799"
     CDS             complement(4509..6806)
                     /gene="recJ"
                     /locus_tag="ACHDPO_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFN3369417.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6948..7391)
                     /locus_tag="ACHDPO_001800"
     CDS             complement(6948..7391)
                     /locus_tag="ACHDPO_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFN3369418.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7392..8180)
                     /locus_tag="ACHDPO_001801"
     CDS             complement(7392..8180)
                     /locus_tag="ACHDPO_001801"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFN3369419.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8177..9118)
                     /gene="rnz"
                     /locus_tag="ACHDPO_001802"
     CDS             complement(8177..9118)
                     /gene="rnz"
                     /locus_tag="ACHDPO_001802"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFN3369420.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9295..9882)
                     /locus_tag="ACHDPO_001803"
     CDS             complement(9295..9882)
                     /locus_tag="ACHDPO_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFN3369421.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10103..11416)
                     /gene="obgE"
                     /locus_tag="ACHDPO_001804"
     CDS             complement(10103..11416)
                     /gene="obgE"
                     /locus_tag="ACHDPO_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFN3369422.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11704..12714
                     /gene="gap"
                     /locus_tag="ACHDPO_001805"
     CDS             11704..12714
                     /gene="gap"
                     /locus_tag="ACHDPO_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFN3369423.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12799..13734)
                     /locus_tag="ACHDPO_001806"
     CDS             complement(12799..13734)
                     /locus_tag="ACHDPO_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFN3369424.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13920..14879
                     /locus_tag="ACHDPO_001807"
     CDS             13920..14879
                     /locus_tag="ACHDPO_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFN3369425.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14965..16059)
                     /locus_tag="ACHDPO_001808"
     CDS             complement(14965..16059)
                     /locus_tag="ACHDPO_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFN3369426.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16248..17009
                     /locus_tag="ACHDPO_001809"
     CDS             16248..17009
                     /locus_tag="ACHDPO_001809"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFN3369427.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17124..17564)
                     /gene="fabZ"
                     /locus_tag="ACHDPO_001810"
     CDS             complement(17124..17564)
                     /gene="fabZ"
                     /locus_tag="ACHDPO_001810"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFN3369428.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT         5060 a         3833 c         3086 g         5628 t
ORIGIN      
        1 tgacaaataa tattctcaag aaacacaaac taatccgaag aattctttgt tttgtcattt
       61 aaatgtaaca tagccgaaaa cgaaaagtaa tattgattta ttcttctaac acataaagaa
      121 cagctgtctc caacttgcag acagctgttc ttatcagtca aacaattgct tggatctatg
      181 atagttgatt gtacgtattc acgacatttt ctactgtaaa tccaaattct tctaaaattt
      241 tagtgccagg ggcagatgca ccgaaatgat cgattgtaat cgttgcgccc tctgttccta
      301 cgtagcgttc ccatccaaat gatgcagcag cttcgatagc cacacgtttc ttcactgatt
      361 taggaagtac actttcttta tattcagaag attgtttttc aaagaggtca aagcttggca
      421 tagaaacaac agaaacatct ttgccttttt cagccaattc tttttgagct ttcacagcca
      481 aatcaacttc agaacctgtt gcaatcaaaa taccttctgg tgtttctcct tgtgatggag
      541 aaagaacata cgcgcctttt ttcaccattt catctgctac ttcttttgta gaaggcaata
      601 ctggaaggtt ttgacgactc aatacaagga tagtaggcgc atctgttgtc tccatcgcta
      661 ctttccaagc agcacgtgtt tcatttccgt ctgccggacg aatcacttga acaccaggca
      721 tgcagcgaac agatgctagt tgttcaatcg gttcgtgcgt tggtccgtct tctccgacag
      781 caaccgagtc atgtgttaag acgtaaacaa caggagtatg ttggattgct gctaaacgaa
      841 ctgctggtct tagataatcg acaaagacaa agaatgttcc accgtagata cgagttccgc
      901 catgaagttg gataccattc atagccgaag ccattgcaaa ttcgcggaca ccgaaccaga
      961 tgttgcgtcc ttcataatgt tcaggagtga aatctttatc tgcagccacc attgtattat
     1021 tggaacctga caagtccgct gaaccacccc agaagcttgg tatagctttc gataattctt
     1081 ggatgacttc tttacttgaa acacggcttg cttgactgct tccaacttca taagttggca
     1141 attctgcatc ccagttttct ggtagtttgc catcaaaagc atcttcaaat tgttgtgcta
     1201 attcaggata agctttttta taattggcaa acatttcatt ccatgcatct tcagcttttt
     1261 gtccttcttc tatcatcgtt tgatggaagc gggcagctac ttcttctgga acagtgaaat
     1321 ctggatactc ccaaccataa acttctttag ccatcttgat gccatcttca ccaagaggag
     1381 caccatgaac agcagatgtt ccttctttag gagcaccata gccgatgact gtttttactt
     1441 cgatcaatgt tggtttgtct gtttcagctt ttgcttcttc aatcgcttta gagattgctt
     1501 ctaggtcatt tccgtctttc actaagatat gttgccagcc atatgcttca tagcgagcac
     1561 caacgttttc tgtgaaagct tttgaagttg gaccgtctag tgaaatatcg tttgaatcgt
     1621 ataaaacgat caatttccct agtttcatat gacctgccat cgaacttgct tcttgagata
     1681 ccccttccat caagtctccg tcaccgcata ttgcatacgt atagtgatcc atcacattaa
     1741 agttttcttt gttatacgtt gctgcaaggt gcgcttctgc cattgccata ccgacagcca
     1801 ttgcaatccc ttgtcctaat ggccctgtag tggcttctac accatctgta tgatgtactt
     1861 caggatgtcc tggtgtttta gaatcccatt gacggaattg tttcaaatca tcgattgtca
     1921 cttgatagcc agctaaatga agcaagctat acaacattgc tgacccatgt cctgccgaaa
     1981 gaacgaaacg gtcgcggtca gcccagtttt ttgatgtcgt tggatttact ttcaggtgtt
     2041 ttgtccataa cgcatatgcc ataggtgctg cgcccatcgg caatccagga tgtcctgagt
     2101 ttgctttttg gactgcttca atacttaatg tacgaattgt gttaacgcca agttggtcaa
     2161 ttttgtcaaa caaaataacc cctcctatta atttaggttt tttttacctt tatttcttac
     2221 actttcattc tataagatgt cacacgaaaa agcaatcttt ttcagtattt tttactaaaa
     2281 gttgtcattt cggttgtgta agcctttttt cttttggatt tcttttaatt tttccggggt
     2341 cacgtcattg ccctcaggat cgacgacttt cattccttcg atatgatgac gcataccgga
     2401 acgaaaagct tccaaatact ctttgcgcaa gttgatttgt tcttgttctt cggcttttga
     2461 gagaccattt tccttctttt tacgtgcaag ttcattgatc cgctctattt tttcaggtga
     2521 cagcatgctc agccctcctt ttactctcct tcatattata taaaaactga aaaaaaaaca
     2581 actagataaa ctaaataaaa tacgaacatt cgtttgattt agcgcttttt atatggtact
     2641 atttatttat caagtgaaag aaggtgtacc ttgtggcccg acaaactgaa tcaagacaaa
     2701 tcgaagtctt acgatatatc catgaacaag taacccaaaa aggatacccg ccgactgtcc
     2761 gtgaaatcgg ggaagctgtt cagctttctt ctacttctac tgttcacggt catcttgcac
     2821 ggcttgaaaa aaaagggttt atccaaagag atccgacgaa acctcgtgca atcgagttga
     2881 caaaacaagg tttagaaaag attgggattc gtccaacaac tattccagta cttggcgtcg
     2941 taacagctgg agaacccatt ttagcagtag aggatgcttc agacttcttt ccaatccctc
     3001 ctaatctttc ttccgaagaa ggcagtctct ttatgctgac aattcgtgga gatagtatga
     3061 tcaatgctgg gatattggat ggtgacaacg tgatcgttcg gaagcaagaa actgctcaaa
     3121 atggcgatat tgtcattgca atgactgccg aggacgaagc gacttgcaaa cgattctata
     3181 aagaaaaaaa ctttttccgt ctgcagcctg aaaacgactt gctcgaacca atcatcttag
     3241 atcaagtatc tatattagga cgagtagtag gactttatcg tagtcatatc tattaattgc
     3301 tactaattaa aagaaaactt tttaaaaaga gtttgagacg ttggtctcaa actctttttt
     3361 cgcccgggtt cttcttcttt caaattttta tcacttccct ctttacaaac cgaacaaata
     3421 ttcgtatact aaatatacga acaattgttc gcataaatta aagaggtgag aattcatgaa
     3481 atcaatgaga cgtcttggct tagtattaac tgttttgttt ttaggtatta ttattggtaa
     3541 tttcggcata cgtccagctt tacttgtgtt tgttccgtta tttactttgt ggttcatgtt
     3601 gtgggatgaa aagaagtacc gtcaatctga gcggcgcaga attcatgaag atcatttcta
     3661 tcatgagccc tactacagat ccaggcaatc ataataagga ttgactgcta attattcaaa
     3721 agacaagaag ttaaactttt acgggggtgt gacaaaaatc ggtcacatcc tttttttcga
     3781 ataaacggtg ttctaaagcc agtttttcgg tattaagtca aattgcggaa aaagtgattt
     3841 tttaaacttc tactggtctt tgcttgtttc catttataaa aaaatagcga ccctcaaaag
     3901 tcagatagag aatctgactt ttgagggtcg ctttaaaatc gcttctttaa gaataacatc
     3961 aagaatagct tcttttttct gcttaatatt ccattaatgt aatgatgtca tatcctttga
     4021 ttttgtcgcg tccatggaga tccatcaatt cgatcaaaaa tgcgcagcct acgactacac
     4081 cgcctaattg ttcgatcagt tcgatcgtcg ctttgattgt tcctccagta gctagcaaat
     4141 cgtcacaaat cagcacacgt tgacctggtt taatggcatc cttatgcaat gtcaatgtat
     4201 ctgttccata ttctaatcca taagtcactt cgatggtttc tcgaggtaac ttcccttttt
     4261 tgcggactgg ggcaaaaccg actcctaact cataagcaac aggacatcct acgatgaatc
     4321 cacgggcttc tggcccaact accatatcaa ttcgtttttc ttttgcataa tttacgattt
     4381 gtttagtagc ttcccgataa gcgtcaccat ctgccatcag tggggaaata tctcgaaaca
     4441 caattccttt tgacggatag tcgggaatac tggcaatata atcttttaaa tccactcttt
     4501 gtttcctcct aggttgttaa ccatttcttt atggtaggaa tatcgctcaa aagcaaaaat
     4561 tcctcaactt tgattttatt gagccgtcgc tggtataatc tgctctcagt caaaggatga
     4621 ctttctgggc tagcgacttt ttgtaaaaca ccgttctcta ttgtaacaaa tttcaattca
     4681 aaaaacacct gtatcataaa aattaataat ttttcaggga tacgcaaata ttgagctatt
     4741 gcttttattt tatgacgtat atcaattcgt tcttgagaat ggatcaattt aaacaatttt
     4801 gcgtactgtt ctcttgtgcc taccccattc aaataggcct catcaggtga aatccccatc
     4861 agataaacac gattgaatga ataagaccga aaaacttctt tcagatccgc taaatcatct
     4921 ggacaatcca taacaactag agagtttggt tttctttttt caattattgc ctttacagaa
     4981 tctagtcctt cgaaaacaat cgcagcttcc tggataatct caggcacgaa tttcaacgtc
     5041 gaagaatcaa atgctaaata aaggctacct tccgacgttc ggctctgttc acggaaacgt
     5101 tttgcccgcc aatcaaatac ttgcagacca cccacagaaa aatcagatac catcagctgc
     5161 ggtttcttac gcccgttcca ttcattgatc gaaagctttc ctaccacatc tacctgatta
     5221 ttcagcagtt cttcttcttg agtaccaaaa ccaaaagcga ccgcatcaag ctgactcgat
     5281 gcatcggaaa ggacaaattt cagatgctgt tggtttgctc cgattctttt gatattttct
     5341 gcttggactt gtcgaaataa aaactgaggc aaaggattat ccgtaccaaa tggcgccaat
     5401 agtttcagct catcaattcg ctctactgtt acttcatttg gcagcaatac ttcatcaatt
     5461 ctcaactcag gccctctcat caagtcaatt tgatgatcga ctatatattg gttcatcttc
     5521 tcctgtagta tagtgacatt ttcacttggc atcgttaaac cgactgctgc atgatgtcct
     5581 ccgaagtaag taaataaatc tcgcatctgg tcaagcattt caaaaagatt caaggcttca
     5641 atactacgtc cagatccttt agctgatcca tcttctttta aagtaaggac aagcgttggt
     5701 ttacccgttt cattcattat tttcccagca acaatgccca aaacgccttc atgccatcct
     5761 cggtttacca atagatggat atgattctcc ttattgacca tcgctaatgc ttcttgtgtt
     5821 atctgctcta cgattgcttt tctttcttca ttgatctcat tcaatttttt tgcttgaacg
     5881 gatgcttcct cttcatcaaa cgtcgcaagt aacgagacgg caggacgtgg atcgcccatc
     5941 cgaccgattg catttagtct gggagcaatc gaaaaaccga tcgttgtttc gtctgcgtcc
     6001 ctcattttta cgccgctttc ttcaaatagc gcctgaagtc ctatccgttc tgaatgatga
     6061 atggcatcga ttcctaatga aacaaggatt cgattctcat cagtcaatga aactaaatcg
     6121 gcgatcgttc ctatcgctac taaatccaaa aattctgcag gcggttcttc caataatgca
     6181 gaagctactt tgaatgctac tccgactcct gccaaatctg gaaatggata gtgccccgct
     6241 ggatgacgag ggtgaacaat cgcataagcg tctggtaaat tctcaggtag ttcgtgatga
     6301 tctgtaatga tcacgtctac accagcttgc tgagcgtatg ctaccgcatc atttcctgct
     6361 accccgttat caacagtgat gatcaactgg attccttctt cgatcttttc ttggtatacc
     6421 gattggtttg gtccataccc atgctcaaat cgatttggca ggaatacttc tacttctgca
     6481 ccaagtaatt ccagtgtttc tttcattacc gttgcactgg tgatcccatc tgcgtcataa
     6541 tcaccgtaaa cgaggatttt ttctccactg attacagctt cttggattcg gctgattgct
     6601 ttatccatat cgtgtatcag atacggatca tgtaattctt gttcctttgg atgtaaaaat
     6661 cggttgatat ccttttcctc atggtaacct ctttgccaca gtaacttacc gacaaatgga
     6721 gataatttca gttcacggat catttggaga aaggattcag aaggctctgt ctcgcttaac
     6781 ttccaatcaa aatttgcttg tctcactttc tcactcctaa cttagttatt atagcaaagg
     6841 aaatcagcaa aaaaaagcag aaagaaagaa taaaaacaga tcagatccgc tagacagatg
     6901 ttcagcagga cctgatcttt tgtacgacca tttatgaaat atccctatta gtcaaaataa
     6961 ttgaagcttt gtttgggcga ttgagttttt tgttcttccg gcgctttcaa ttgactgatt
     7021 tgtgcggttt tcgcttgtaa ctccgcctga taagcagctt ccaactccgc acgttcgttt
     7081 ctaaactcgc gttgctgttc ttcttttgct tcttcaattt tcttttgaag ttctgtttga
     7141 tattctgaca tttcctgagt cagctgtttg atttgctttt tttgctgcca tagtgttgcc
     7201 gaagcagtca aaaatacaat cagtgcacca atcagcgcag aaccgatgat cactaagatc
     7261 aatggcgcag aaaaggaagt gaagccaaaa cttacaggaa catttttatt gttcaataca
     7321 gcaaaaagaa caataatcaa aactaaaaca aatccaagaa tcacattgct ttgctttttc
     7381 aattccttca cctacttttt gttaaaaatt ccgctggcta aataatcacc aatcgttgga
     7441 aacagcgtat aaaattttga tgcaacttct aaaataaacg gttgattgat ttcccgtttt
     7501 ggatgtctca tattgcggac gatcattttt gccaacttgg caggttctaa aacgatttgt
     7561 ccgacttttt ccaaatagct tccgcttgga tcagccttat cgaagaaatt tgtctcgatt
     7621 ggacctggat tcactgtcgt aacagctacg ccaagtggtt tcaattctaa tcgcaaagcg
     7681 ttggagaagc caaggactgc aaatttcgtg gcagaataaa ccgttgattt tgcagttgcc
     7741 atttttccag ccatagaggc gatattaatg atatgacctt gtcttctttc tgccatatcg
     7801 atcgcaaatt tttgtgtcaa aaccatcatt cctaagatgt tgacttcaaa catatcgtat
     7861 gcttttccaa ggtcgaatgt aaggaagtct tcgaaaatcc caaaacccgc attgtttacc
     7921 agaatatcga cgcgcccgac ttcttccatc accttttcat ataattcgtc cacgctttca
     7981 ggattgctga cgtctacctt gaaagcataa gcctctttgc cgctcaagcg tctgcactcg
     8041 tctctgacac cttctacaaa tgccattctt cgtgcgcaac ttataacgat tgctccttgc
     8101 tttgctgctt cataacagat ttgtgcgccc agaccgcctg aactacctgt tactaaaaca
     8161 actttatctt ctaaattcat gcctcttcct cctcgcgaaa tggaatctca atgctatcaa
     8221 aatctttcat aatcgtcgtg ttttcaaaca cttcttgtgc ttctttttca agctctaaag
     8281 ctgcttttcc taaatatctc gcactgatat gagtaagtag cagccgtttt gcctgcgctt
     8341 cttttgcaac ttcagcagct tgatgagtcg tggaatggaa atagttgtgc gccattcttg
     8401 cttcatcttt attaaatgtg ctttcatgta ccagaatatc gctattttcc gcaagcacaa
     8461 cggaattatg tgtttttctc gtatcgccta aaatagtcac gattcgtcct tttttatctg
     8521 gacctacgaa atcttttcca ttgatcgtcc gcccatcttc tagttggatc gtttcacctt
     8581 gcttcagttt gccgtacagt ggtccagctg gaatacctaa ttcttttaga cgatccacct
     8641 gcaattctcc tttatgatca tgttcaacca cacgataacc aaaactgtcg atcccatgat
     8701 ttagtttttt tgtataaaca gaaaattgct gatcagtaaa aatcggggct gtttcattta
     8761 gctcaatgaa tttcagcgga taacttaaac gcgtttgcga aatacctaaa gagactttta
     8821 tgtattcctc tatccctttt ggcccgtaaa tctctaatgg cgtatcccca ccttgaaatg
     8881 accggctgct gatgagcccg ggaagtccaa aaatatgatc gccgtgtaaa tgtgtaatga
     8941 aaattttacc gatttttctc ggacgaatag tcgttcgcaa aatctgcatt tgcgtgcctt
     9001 cgccacagtc gaacaaccaa acttcattgc gctcgtctaa aagtttcaat gctatacttg
     9061 tcacatttct atgttttgca ggaacacctg cacctgttcc taaaaattgt aattccataa
     9121 tctacctgac tttctttaag ttcctcttta attttagggt aaaaagaagg gataatcaac
     9181 cgtaagtcga gaatgggttc aaattaaaaa taacgttcta aagcgatagc gttttctttg
     9241 aaaattacta taaaaacagc agcgaacccg tttgagatcc tctgctgttt tttattaatt
     9301 tgaagatcca gaactttcat tgtcgttgga agtttgcgga tgtttgtcct tccaagtctt
     9361 ttgtgcagct tctttcgcat gattttcagc ttctttcgca tcatgcacat ctttttcgac
     9421 atcttcataa tccaagcgag taatttctcc gcctaattcc atcattacca attgattcag
     9481 tgggcgattg tcctcttcat cagcaatcaa gatcagtcct gtagctcctt caccgatttt
     9541 atttcctaca aagtcgaaca cggtctgggc atcttttatt tctttggcat cttgtgtcgc
     9601 accgatcatt cctccggcaa accatcctaa taaaatccct agcggaccac ctaatacacc
     9661 aaccaacatt ccgattaatc cacccgtaga agatttgtta ttaccggtaa agtcgataaa
     9721 atcttctatt ttgaattgat gtgtcccatt aggatcatgg ctgacaactg ccatctgttc
     9781 tcctttaatc gaacgaacag catgtaactt tttgatttct gaaaatgcct gatatgcctg
     9841 gctttctact tgaaaattta aaatgattac tcgtttgctc attaaaaacg cccctttcat
     9901 accttcttgt tatttatttt acctttaatt gaaaaataag aaaagaaaag cactcttttt
     9961 ttccaataaa atagggctgt gacaaaagtc gtatcacagc tcctttttcc gaataaacgg
    10021 cgttcttgaa gctgatcact tctgtcacaa cctcccttaa atctgaatct atattttttg
    10081 gtatttgttt ttatttgctt gcctattcga caaattcaaa ttcaaactca ccgatacgta
    10141 caaggtcgcc atctttcgca ccgcgtgccc gaagagcttc atccacaccc ataccacgta
    10201 attgacgagc aaaacgcatc actgtttcat catgatcgaa attcgtcatt tggaataatt
    10261 tttcgatctt ctcaccagat aagatccacg ttgcatctga atcacgatcg atttggaact
    10321 caggaccttc tggattgaat ccatagtgta cagtttcttc ttccagttct tcttcgtaca
    10381 atgggaattc tggcgttact tctaacaaat ctgctgtagc attcaataac gcgtccaatc
    10441 cttgtcgagt cactccagaa attggaaata ctgggatgtc atcagcaaat tcatcttctt
    10501 tttccttgtt cagctgttct ttgaatttca ctagattttc cggtgcatcc ggcatatcca
    10561 ttttgtttgc cacgatgatt tgcggacgct ctagcaagcg taagttataa gtagataatt
    10621 ctttgttgat ggcaagatag tcttcataag gatctcgtcc ttccatccca ctcatatcga
    10681 tcacatgtaa aattactcgt gttctttcga tatgacgaag gaattgtgta cccagcccaa
    10741 caccttgcga agctccttca atcaagcctg gcaagtctgc tgcggcaaaa cttctgccat
    10801 cacttgtagt aaccattcct agattaggta cgagcgtcgt gaaatgataa gcgccgattt
    10861 ttggacgagc agatgaaata acggatagta aagtcgattt cccgacagat ggaaaaccta
    10921 caagtccaac gtctgccaat actttcaatt ctagttcgat ttttcgctct tgtcctggtt
    10981 caccgttttc agcaatttcc ggtgcaggat tccgaggaga ggcaaaacgg atattccctc
    11041 gtccaccgcg tccacctttt gccacaacta gtgtttgacc attttcaatt aaatctccta
    11101 aaagagcacc agtctccgca tctcggacag tggttccttg tggtacttta acataggtat
    11161 cttctgaacc acgaccgtgc atccctttac tcatcccatt ttcacctggc tgcgctttga
    11221 aatggcgatt gaaccgaaaa tccatcaatg tacgtaaccc ttcatcgacg atcaagatga
    11281 catcgccgcc acgaccaccg tctccgccag ccggtccgcc gtcaggaacg tatttttcgc
    11341 gacgaaatgc aaccattccg tctccgccct tgccagcttt cacatcgatc gttacttgat
    11401 ctaaaaacat ggacataatt aagtcctcct attattcatt tatttatttg actgcctgaa
    11461 tttccacaat aaacaaaagt cttacttatt ttatcggtga aatctgattt tgtctatcat
    11521 ttcagcaaaa agattgttta ccttcttctt tttttatcat ttggtaaggt ttccaacctt
    11581 ttttctgcta ccaagtataa ttttttgaca aaatattctt tgcgtagcag aataacagtg
    11641 tattaattgt attaattgag gatgccgttt cacagcaccc ctaataaagg aggaactttt
    11701 gatatgacag taaaagtagg tattaacgga tttgggcgta ttggccgtct ggctttccgc
    11761 cgcatcaaag aagtctcaga tgatattgaa gtagtagcaa tcaacgactt aacaagtcca
    11821 actatgttag cacaattatt gcaatttgac tctactcatg gtacttatcc tggcacagtt
    11881 actgcaacag aagactcaat cgtagtggat ggcgaagcaa ctcgtgttta tgcagaaccc
    11941 gacgcaagca aaatcccttg ggcaaaagaa aacggtgtag atatcgtact agaatgtact
    12001 ggtttttata catctgaaga aaaagcaaaa gcgcatttag atgctggtgt caaacgagta
    12061 gttatttctg ccccagctgg tgctatgaaa accatcgtct ataacgtcaa tgatgataca
    12121 ttagatgaaa acgacaaaat catctcagca ggttcatgta caacaaactg tttagcacct
    12181 atggcttatt tcttaaataa tgaatttggg atcgaagttg gtacaatgac aacagttcat
    12241 gcctacactt ccacacaaat gctcttagat ggacctgtaa aaggcggtaa tttgcgtgct
    12301 gctcgttcag ctgctgacaa tactatccca cattctactg gtgctgcgaa agcaatcggc
    12361 ttagttatcc ctgagctaca aggaaaatta caaggacacg cacaacgtgt tccagtcgtt
    12421 gatggttcat taactgaatt ggtttcagta ttgaaaacaa aagtaactgc tgatcaagta
    12481 aacgaagcaa tcaaaaaaca cacagttgac aatccttcat tcgggtatga tgaccgtcaa
    12541 atcgtttcta gcgatgtcat tggaacaact caaggttcga tctttgaccc aacgcaaaca
    12601 gaagtaacaa ctgctggtga tttccaactt gttaaaactg ttgcatggta tgacaatgag
    12661 tatggattta cttgccaaat gattcgctta ctagaaaaat tcgctaactt gtaatttgat
    12721 agatcaatcg ataaaagaag cctttgactg gatccagtca aaggcttctt tcttttcatc
    12781 ccctactttt aaactcgttc aatgaacata ttggcttaaa aattgttgga ctacttgctg
    12841 atatttttca ggatctgtct tgtatgcttc cgcatgctcg gctcctttta caacatactt
    12901 ttcttttggt cccttcgttg cacgatagac cttatctaac atttcaaatg gtacaaatgt
    12961 atcttcgtct ccatgtataa agagcattgg gcgctggttt ttcttcaatt gttccactgc
    13021 atttgcttca ccgaaaaagt agccagcacg gacttttgtc actagactcg ttacttgcat
    13081 aagcggaaat gctggaagac taaacatatc gtctagctga taagcaagct catcatgaac
    13141 ggaagaataa ccgcaatctt caatgattgc tttcacatta tctggtagtt tttctccgct
    13201 agtcatcata actgttgctg ctcccatgct gacaccgtat agaacgattt cttgcgattt
    13261 tccattgttt tctagcactt tgtttatcca ctgtacatag tctttacgct ctggccatcc
    13321 aaatccaatg taatcccctt cgctttttcc atgtcctctt gcatcaggaa caaggacatt
    13381 gtaacccata tcatgaaaca tctttgcgta attggtcatc gtttcagcgt ttcccatata
    13441 gccatgagcc acaagagctg ttttttcact tttcgtttca gcaggaagat aaatcgctga
    13501 taatttcaga ccgtcttttg aagtgatggt ccaatcgctt cggttttctt ttgaactaaa
    13561 ccatttatgt gcatccgttt ctttggatgt ctgtgttgta ccaggtgtat cttcgtctaa
    13621 aaagtctttc tcagaaggca caacagcata attataaaaa taattccctg caaacactaa
    13681 cgcaacaatc agagctaaag cgacgcctaa aaggattttc atccaaagtt tcataaatca
    13741 tccatctcat ttctcttttt tcatataacc ttgaattagt ataatcaaag aatctctact
    13801 atgcaatgtt catttttata acccgcgaat tgtaaaatta agttagaaaa ataaaaaggc
    13861 atttatggta cactcaaatt gtatttccga cgaaagaaaa caaaggagtg taaccataaa
    13921 tgacctacaa acatcttacc atagacgaac tgacaatgat agaatcatat tatcttcaac
    13981 ataataagcc ggttgaaatc gctaaccgaa tgggacgtgc tatacaaact atttataatg
    14041 tagtcaataa gttcaagcaa ggcaagactg ctcttgatta ttggcaccag tataaagaaa
    14101 ataagaaaaa atgtggtaga aaagtcattc aattacctgc tcatgaagta gattacatta
    14161 aagagaaagt cactcttggt tggacgcctg acgtcattat cgggcgaaaa gaaaggtctg
    14221 tttcatgcgg tatgagaaca ctttatcgtt tattttctaa aggaatattt gatattgaca
    14281 cactaccgat gaaaggtaaa agaaaaccca atggccatca ggaaaaacgg ggaaaacaac
    14341 agtatcagcg ctcaatccat gatcgacctg ataattatcc tgatttcaat tctgagtttg
    14401 gtcaccttga aggtgatacg atcgttggca ttcatcataa aagtgccgtc attactttag
    14461 ttgaaagatt atctaaagtc attatcacga ttaaacccaa cggccgtaag gcattagata
    14521 ttgaaactgc ccttaatcaa tggttttctc gcttccctaa aaacttcttt aaatctatta
    14581 cgtttgactg tggaaaagaa ttttctaact ggaaagccat tagtaaccaa catgatattg
    14641 atatatattt tgcggaccct ggaacacctt ctcaacgccc attaaacgag aattctaacg
    14701 ggattctgcg tcgtaatgga ctgccgaaat caatggattt tagaaaagtg aatcagacat
    14761 ttatttccag tgtcagcaat caacgtaatc atattccaag aaaatcattg aattacagaa
    14821 caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc ttaatttgac
    14881 aaatcataac ctataaaaaa acaaaataaa aaagcagaaa taactggcta tttctagcgg
    14941 attatttctg caataactaa ttatctattt tttattttca attaatttaa agcttgacca
    15001 tggtttcaaa aagtcaagga ggaataattc gtcatcggag attcttccta caacattgac
    15061 acgtccgtcg tttttcatat ccttcaaggc gatttgtgtt tctcctttgt attgaccgta
    15121 cccttcattg tcaatcagta catccccatg atgcatatct cgcgtattat gaggcgggaa
    15181 atctttatct ttgtagtata cacgagtcat cgttgaacga aggatatatt ctgagcgatc
    15241 ccctcgataa ctatgaaggt tatcaaacaa gcagattcgt tcgttttctg taataccttc
    15301 ttccgtatct actttcaatg ttggataatc cgcgttaaat gcttctgcca tttctttcaa
    15361 ttcttcttca cttgcgtacg catttccaat agaaatatca tcaatcaatc ctgtaaggat
    15421 taaatgcttc acttgtgtcg caatttcaag atctcggtgg tcttccagcg tgcacaagcc
    15481 atcttgcgta ggccaagggc caaactcagc agattgcgaa ttgacgaatg ccatcgtatt
    15541 caaattatat tttctgaatt tttctgaaca aaaaacaaag tgttcgtatc ctaaaccaga
    15601 gtatcgatga ggataaaaat tatgagaacc taataaatta tccgtgtttg gcgaataact
    15661 catgatgttg tcaacgtaat tcgtgcccga actcatattg atctcgattt tgataccaaa
    15721 aggattgcgc gtcatttttg cttcttctgc tcctgtgaat ccgatatcta agcggacccc
    15781 gtaggcaccc atcttatgga aaaaagataa gtcatcgtaa gaaatctcca actgttcaaa
    15841 taacgctgga ttgatatcaa ccattacttc catgcctagg ctattcgcgt aatcaactac
    15901 ttctttaaat tctgaaagaa ctttttcttt atcatcattg atctgcagca aactggtaaa
    15961 aacccgttta tacccatact tatgagctaa atccaagtac gctttgtcct tttcaaatgt
    16021 tgaccgttct ggataaatcg agattcctaa ttttcccata ttaccatttc ctcctgcatc
    16081 ttttcgtttt tgtatccact tacattatag caaacacaaa gtaaatggtc tacacctttt
    16141 ctttttcttt taaaataaat gataaattcc aataatttaa gtaggtattt tccctctatt
    16201 ttgttatcat taaagataac aaaatagtaa attggaaagg aacagttatg aagaaaaata
    16261 aagttatttt aagtattagt ttagcagcag cattgctgtt tgctgctggt tgttctgcaa
    16321 acaacacgac ttcttctagt tcgtctacag aaagttcaaa aagtacatct actgcggaaa
    16381 gcacgactgc cagtagcgtc gatttgaacg cattggaatt accacaattg acgaaagatg
    16441 tcgccgaaaa tgaagatctg gtcgaaatgg tgacgaataa aggcacaatc aaaatcaaat
    16501 tatttcccga acacgcacca aaagcggttg aaaactttat gacacatgca aaagacggtt
    16561 actacaacgg actgactttc catcgcgtca tcaaagattt catgatccaa ggtggcgatc
    16621 ctaaaggcga tggcactgga ggggaaagca tttggggaga aggatttgaa acagagatca
    16681 acaaccacct ttataatata agaggtgcgt tatctatggc tcgctcacaa gatcctaaca
    16741 gtaacggcag ccagttcttt atcgttcaaa atacagatga tatgcatgat ggtcttttaa
    16801 aagacgacta tcctcaagca atcatcgacg cttataaaaa cggcggttat ccttcactag
    16861 atggccatta tactgtcttc ggccaagtga ttgaaggaat ggatgtcgtg gatgctattg
    16921 caaatatcga aacagatagt tcagacaaac caaaagaaga agtaaaaatc gataaaatca
    16981 atatactgca agaagcaaaa caaaaataaa aaaataacgt ctgaatcctg catagatgac
    17041 aacgtatgct aggattcagg cgtcttcttt ttacataaaa agcaagtaag cttccttttg
    17101 ttttgctata tcaggtttta tagtcaagca ttttggttga cgatgaacgt gaactcgcac
    17161 tcacagactt ttttatcatc tacatatgct gcagataacg ctgtaccgac tgatcccttc
    17221 attttggtga tttcaaaatg acatttcagc acatctcctg gaacaacttt ttgacggaat
    17281 ttggccttat tgatcccacc gatataagct ctttttccta gaaactcttc tgattttagg
    17341 ataagtatcg aacctgcttg tgccagtgtt tctagaatca acgcacccgg catcactgga
    17401 ttgtcaggaa agtgaccttg gaaaaaatct tcattgattg ttacattttt tgtcgcaacg
    17461 atcttttttc ctggttctaa agtatctaca taatcaatat aacaaatagg ataacgatta
    17521 ggaatcaatt ccattacttc agtagcagat aatacgtaag acataattaa actccttctt
    17581 tcaggcaatt gccattttca ttacttt
//
LOCUS       DAZAOD010000055        17556 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000055 DAZAOD010000000
VERSION     DAZAOD010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.056"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            10..975
                     /locus_tag="ACHDPO_001811"
     CDS             10..975
                     /locus_tag="ACHDPO_001811"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFN3369429.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(1074..2246)
                     /locus_tag="ACHDPO_001812"
     CDS             complement(1074..2246)
                     /locus_tag="ACHDPO_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369430.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(2233..3378)
                     /locus_tag="ACHDPO_001813"
     CDS             complement(2233..3378)
                     /locus_tag="ACHDPO_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369431.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(3392..4324)
                     /locus_tag="ACHDPO_001814"
     CDS             complement(3392..4324)
                     /locus_tag="ACHDPO_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369432.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            4441..5520
                     /locus_tag="ACHDPO_001815"
     CDS             4441..5520
                     /locus_tag="ACHDPO_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFN3369433.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            5517..6135
                     /locus_tag="ACHDPO_001816"
                     /pseudo
     CDS             5517..6135
                     /locus_tag="ACHDPO_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(6245..6472)
                     /locus_tag="ACHDPO_001817"
     CDS             complement(6245..6472)
                     /locus_tag="ACHDPO_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFN3369434.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(6575..9163)
                     /locus_tag="ACHDPO_001818"
     CDS             complement(6575..9163)
                     /locus_tag="ACHDPO_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFN3369435.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(9183..9842)
                     /locus_tag="ACHDPO_001819"
     CDS             complement(9183..9842)
                     /locus_tag="ACHDPO_001819"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFN3369436.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLLNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(9891..10394)
                     /gene="trmL"
                     /locus_tag="ACHDPO_001820"
     CDS             complement(9891..10394)
                     /gene="trmL"
                     /locus_tag="ACHDPO_001820"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFN3369437.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(10615..11481)
                     /locus_tag="ACHDPO_001821"
     CDS             complement(10615..11481)
                     /locus_tag="ACHDPO_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFN3369438.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            11590..12231
                     /locus_tag="ACHDPO_001822"
     CDS             11590..12231
                     /locus_tag="ACHDPO_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFN3369439.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(12293..13654)
                     /gene="mgtE"
                     /locus_tag="ACHDPO_001823"
     CDS             complement(12293..13654)
                     /gene="mgtE"
                     /locus_tag="ACHDPO_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFN3369440.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(13672..14571)
                     /locus_tag="ACHDPO_001824"
     CDS             complement(13672..14571)
                     /locus_tag="ACHDPO_001824"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFN3369441.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(14573..15370)
                     /locus_tag="ACHDPO_001825"
     CDS             complement(14573..15370)
                     /locus_tag="ACHDPO_001825"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFN3369442.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(15348..16052)
                     /locus_tag="ACHDPO_001826"
     CDS             complement(15348..16052)
                     /locus_tag="ACHDPO_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFN3369443.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            16183..16758
                     /locus_tag="ACHDPO_001827"
     CDS             16183..16758
                     /locus_tag="ACHDPO_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFN3369444.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            16876..17553
                     /locus_tag="ACHDPO_001828"
     CDS             16876..17553
                     /locus_tag="ACHDPO_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFN3369445.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         5189 a         3780 c         3126 g         5461 t
ORIGIN      
        1 gaggaaatca tgaaattcca ttatcatata ttgatcaatc catcggcagg cagcggaaat
       61 ggctataaag tagcagaaag aattttaccg gtattaaaaa ataagcatat tgactataca
      121 cttcattata gtgaatacaa aggacacgat gctgagattg ctgaaacttt ggcaaaagaa
      181 acattgattc cttggataga agaagaacag aaaacaatcg atactttccc ccttttgatc
      241 atcgtaggag gtgacggcac cttacatcag gtacttgata ctttctatca gatggaagta
      301 gaattcccag ttgcttatat tccagcaggt tctggaaatg attttgctcg aggggcaggc
      361 cttccaaaaa atcccaaaaa aggacttcag ctgattttag cagctcaatc accagaaaaa
      421 gtccacataa tggcttatga agaaaaaata agtgaaaaaa aaggaatagc tgttaataat
      481 ttcggtatag gattagatgc agctatcgtc catgcgacaa atcattcttc cacaaaaaag
      541 cgattgaaca aatacaactt aggatcattt tcgtatttat tctctattct ccgtgcttta
      601 ttcactcaaa aaggatttcc aattctggta gatgcaggag gaaaacaatt aagtttttca
      661 aacgcatttt tatgtacagc aacgaagcat cctttttttg gcggaggaat cgcgattgtt
      721 ccaactgctg atgcgtctaa accagtcatt gattttgtcg tggtcgaacg aatcaatttc
      781 tttaaaatct tgtggctcat tcttttactt atacagaaaa aacaattgaa atcgaaatat
      841 ttccatcact acacaacaaa cagattacgt atcgtttcaa caacaccgca acatggtcaa
      901 gaagatggag aagaaatgga aaaacgacct tttgatatca caataaccac aactaaacag
      961 ttgttttggt gttaataaaa gaggttttgt cagaagctac atctggaaca ccgtttattc
     1021 ggaaaaaagg actgtgacac gacttttgtc acagtccttt ttttactatg cagttaattc
     1081 tttgcccaat tgggttgcca tcgatagttt ctttctttac ccaaaataaa ttggatcatt
     1141 gaaaacaccg cagcaaaagc aactaagaca caaccattga accaaaaaga ttctgcaaat
     1201 gtttgattgt aactgagtgt ttcactgatc aagttattat tttgaacaaa ccaatatgtt
     1261 ggtgtgaatg ccgctatttt gctaaccatt tctggcaagt attctgctgg tacaaacacc
     1321 ccaccgataa agcaactgcc tgtgataaaa atatctttga tcccaccgct ggtttctgag
     1381 ttttttacca atgaagtgat acaagccgaa aagctaatga tcggcaataa aaacaagaaa
     1441 gtatttaaaa tatgatacca taccgttata tcccacgagg tgtggatcac taacagaacc
     1501 attagaagta agaagccact gaacaacagc agcgagtaac taatcaaact aaaggttact
     1561 ttgcgattca agtttcgttt ggtaatgggc gcactctggt ttcgtttact gatctctttg
     1621 cgattaaacg ctagattgat gacgctgaaa ccgctaaaaa tggatagaaa caacccataa
     1681 gacaagaaat taaaggttgt gcccgtcaac agctttttca tccgctgact atatcccgca
     1741 cttagctcaa cttctccagt aaccgagagt gccatttgtg tctgttccat agctgcatcg
     1801 attgttttat cttcttcttg aaacagaatc agtgtttgca aaaaggtgtt cacttgctgt
     1861 gtaacaactg ttttagaaaa ggcatctggg cgactctgta tcttgatcgt cgccatcttt
     1921 cctacttcga cttgttcggt aaagtctgca ggcagatgta agataatgtt tacacgatta
     1981 aaataaagag catcatcgat ttctttttgt gaggttccat ccaatgtaac gactgtttcc
     2041 ttgtcattca aatatttacg aaggccatcg actacaggcg actcttcttc actaatcaag
     2101 gcgattttcg catcttgcag agaggtattt tcaacatcaa tattttgcgc aaaaaagaat
     2161 gtggcaacaa cagtgataat tacacctatc agtaaattcg atttatttgc tttaagcaat
     2221 gtccaaatcg ttttataaag cgtcataacg cacccctctt tccatccaag catttcctaa
     2281 cgcaaaaagg aaaataaatc cgatcaacca tagaagattg gtataaaaac tagccaaatc
     2341 agtgtagaaa taaagtttat acaaactttc gctgatcaag ttgacgagat ttaattgacc
     2401 aacaatcgga atatgaagat caatccaata cttcacttgt tccgacccca tcataccagc
     2461 aaaaaagctc atcgcaatcg tcactgaaat caagatgcta tccttttgca ccagattcat
     2521 ttttggtatc aaattaccaa ccaatgtacc taacaaaatc gcacacaacg accccagagc
     2581 ggtaacaatc atcaaccatt gccaacgttc accaaagtct acttgataga taaaacgaaa
     2641 gacagctaac ataatataaa tctctgtcaa aacaatcgta aagcttgctg ccaaattagc
     2701 gattgaaact aacgattgct ttctaggaat caaggacaag cgaataccat ttgacgattg
     2761 atttgcttgc tgatcctgta cattgcggac cccccacatc gtcccgtaga gaatcgccat
     2821 tccaatcaga gtgaagaaat aaaaactttt gaaactcata ttacgacctg catgaacttc
     2881 ttgaaaagat acttcttgtt caaaaacagt catgatgggc gcgagatcaa cgttctccac
     2941 ttctgccact ttactcgaaa ttataccaat acgctgtaaa aattgatcca tgacgttttt
     3001 catcaacgtc tgactcattc ctgcttgacc cacatggagc gaaacagatg aaccatcaat
     3061 gagataaaaa ccagccaaat catctgcatt tagcttttca ttcgcttcta cttccgatag
     3121 ttcctgtact tcaaataatg gtttatcatt gacttcgact tgttctaaga ctgtggtaaa
     3181 attttccgaa agcgctgttt gatccgcttt gattacaatt ccagtattaa tcgtttcaag
     3241 attgccacct tgatcaatct cgccaaaggc cgccataaac atcaatccta aaagaattgg
     3301 aaaggccaat gtccaaaaca acatggattt atttcgcagc agtatttttg tgcgatattt
     3361 ataaaaatgc caaaacatta tttcccctcc tctagtctct caaatccttg ccagtaatct
     3421 ctaaaaagac atcattcaag gacgcttctt tggttgctat ttttccgtaa ctgatctttt
     3481 cttcttgtaa gattgtaaga atcggcaaca atactgtatt tagttcagta gttgttactt
     3541 ggagctgacc ttttttataa gcgattccat cagaagctat tgttcgctga atcgctgaca
     3601 acacattttc tgggagtaat gggatgtcga tcgtcaaacg atccgccgtc cgtaccatat
     3661 cttttagaga ttctttggtt cctttagcaa tcacctgtcc ttgatccatg atcacgatct
     3721 ggtcgcaaag aatttctact tcttccatgt aatgtgttgt atagacaatg gttgctcctt
     3781 gtcgattcag ctccttgata ctttctaaaa ttttattccg actttggggg tctacagcta
     3841 ctgtcggctc atctaaaaaa attaaccgcg gcttgtgggc aatcccacat gcgatgttca
     3901 accgacgttt caagccacca ctaagttctc ctggacgaaa cgaaacatat ttttctaatc
     3961 ccactaattg aatcacctct tcaatcaagg ctttcctttt ctctttttcg gaaacatata
     4021 aaccgcaaaa ataatcgata ttttcttgca cacttagttc gtcaaagacc gcaacgtctt
     4081 gaggaacgac cccaatcatt gccttgacag cataattttc aggagtcatt gttgtcccga
     4141 acaatttaat ggttcctttg tcataattta acaaagaaag catacagttg atggcagtcg
     4201 atttcccact gccgtttgga cctaacagac ctaagacttc tccttcttgt acttgcagat
     4261 caaaatgatt caatgctaca aaatctccat agcgtttgac taatttatca atttcgataa
     4321 tcatcatgaa aaactccttc caaatttctt gttgatctga ctataataaa gtgcaagaaa
     4381 agaaactagt gacgattggc taaaccacac atgacatttg tcacaatgaa ggagtctgct
     4441 atgcataaat ctcggctact caacgaaact agctttctac tggttatctc attgcttttg
     4501 ctggtaagtc aaggattcgt tgctatgcaa gttatctatt tattgatcgc cgttttattc
     4561 actggtgtca gttatttact gcctacaaag ccaaattgga ttttccaagt tattctattt
     4621 cttttatgtg cctttttacc tgatcttgtc ctgtttctgc cagcgacgat gcgagtgatc
     4681 gcccctgaag aaagccacct tgattacttg tttttgttag gttttttgtt gatttcgacg
     4741 gttggtaatc atccccccat caaggtcgcc tttgtcgtaa ttttgctgtt tttttccttt
     4801 tacttacgaa aaaaagatca acgaacgacc gatcttgaga aaaagtacat tgtctccaaa
     4861 gatactcatt gggaaaaaca acaagagtta tcggaacaaa ataaagcatt ggccctgtca
     4921 caagaaacac aattagcctt gcaaattgtg gaagaacgga accgaattgc ccgagacatc
     4981 catgacaatg tcggtcatct gctgtcaagt gcgattttac aaattggtgc gcttgaaatg
     5041 atcaatcaag aaccaaaact aaaagaacca ttagaaaatt taagtgccac cgttcacact
     5101 gggatggatc ggattcgtca aagtgtccat gacctccatg agacatcgat ctcttttcaa
     5161 cactccttag agtttctgat cgctgatttt ccttcttctg ttacgattga aggaaacttg
     5221 tttgaaggat tgaatgaaac gcagcaaaac tgcttcttaa tggtcatcaa agaagcctta
     5281 accaacagta tcaaacatag tcatgccaaa accgttgttt tacattttcg aacgttgccg
     5341 gccttttatc gcttgcaaat cacgaatgat ggcaccagcc cacaaaaaaa ttctgctccc
     5401 ggtattggtt tgaaaacgat gcgtcaacgt gttcaagaac aaaagggaca agtccatatt
     5461 ttccaagaaa accagcaatt tcagttaacg atcattttac caagggaggg acaccaatga
     5521 taacagtagt cattattgat gatgatccat ttgtgacgaa atcgttacaa accattttag
     5581 aaagcacgaa agagatccgt gtgttaggca ttggtcattg tgccaaggat gcgcgaaacc
     5641 catcgtcccg atgttttgct gacggacatc cgcatgccta aacaaacggg catcgatgct
     5701 gccaaagaaa ttttggctaa atttcccaaa gccatccttt tgcttttgac gacattcaaa
     5761 gatgaagaat acatccgcga agcattttcc atcggtgtca aagggtattt aatcaaacag
     5821 aacttgcaag cgattattcc ttctgtcaaa tccgcttata atggacaggc cgtatttggt
     5881 aatgaaatca tcgagacttt cactcaaatg atgaagaata aaccgacgat tgatagtcat
     5941 gcttatgctt cttttagtga acgtgagctt gcaatcatca aagaagtagc tgccgggaaa
     6001 aacaataaag aaattgcaga tgccttgtac ttgagtgacg gcactgttcg caattacatc
     6061 agccaattac tagaaaagct agatttacgg gatcgcacgc aattggctat ctatttttat
     6121 cagcatttgc aataagtctt atctaacaca aaaaaacctg aatgatgctc cttcgcatca
     6181 ttcaggtttt tttcacatct tctattcaat tgtcccgcaa accatttcct cacgattgaa
     6241 agaatcaagg attcgcaggg ctgccaggat tcgttggatt gttcggcgtg ttaggcggaa
     6301 aaataggcgc cttgtctaac gttttttcta gttttgattc ttcacgatcg tctcgttcta
     6361 catcaggact ttcattcaat ttgaattctt tttccatctc atctaacttt ttaaagtcat
     6421 tgccagattc ttttgctaat ttcgctaatt tatcttcggt ttctttagcc ataaagtaac
     6481 gccccccttt tgatttcagc ttagcatatc acactgaaaa aacaaaagaa aacgctaacc
     6541 aacgatcatt tttagctatt tctcatcttt aaaatcaagc attttttgcc ggtataaaat
     6601 cgtagggaga actgttttcc ataccaatca tcggatctac taactggtta tcgatcactt
     6661 ctgctgtaag aacgaaatct ttagaaacag caggttctac ctcttctttc ttttcttctc
     6721 caacaaatga agaaaacaga tctggttcca ctgtttccat tacttggttt ttcgtttcat
     6781 tcgtcccact gtcatcttct acaggtagct tttcttttac aacccgtggc tcttttgtat
     6841 agttcccatc ttcaaatgga tcatttccga ccaaagaatc ttcataagct gctagtttgg
     6901 tccggagagt gatattcatt ttatcattat ccatgatcct tgatttcaac gtagtcatcc
     6961 ggcttgctga ttcattcgct acacaagtga cataggcttg ctcttcccct aacaaaatca
     7021 acagttcctt actgcgagtc actgccgtgt agagcaaatt acgctgaagc atccgctgat
     7081 attgatggac catgggcaaa ataaccatct tgaattcact gccttgtgat ttatggattg
     7141 agcaacaata agaaagagtg attttattcc attcgtttct tttataagtg acctcatttg
     7201 catcaaactg gataactaat tcatccactt tatcttcaga atcttttgcc aagatgatac
     7261 ccgtgatttc tcccatatct ccattgaata cattcaattc gggagtattg actaattgga
     7321 ggactttgtc tcctatccga taaacggtgt cgttccaatg tacttccttt tttccaggtt
     7381 tccctggatt gaatatctcc tgcatcattt tatttaacgc atcgatccct gcaggtcccc
     7441 gatacattgg tgctaatact tggatatctt gtgcacggaa tcccttattt ttcgcttttt
     7501 ccacaatttt agagatcaag ggttcaattt gataagcatc acttcggaaa taggaacgat
     7561 ctttttgatt ctttgtgaaa tcttttggca gacgtccttc tttgatctca tgggcaagag
     7621 gaataatact agaaccatca ccttgccgat aaatctgatt gagttccatt ttgggaattt
     7681 gttcgatttc caaaagatca tggagtactt gaccaggacc gacagaggga agctgatctt
     7741 tgtctcctac taagataact tgcatattcg tcggaatcgc tttgaataat gtgttagcca
     7801 gccatgtatc gaccatagac atctcatcaa caatcaaaag tccgccttct aattctttcg
     7861 tactgactga aggtgttttt tcccgtccat tcagccccag aagacgatgg atcgtactgg
     7921 caggcagacc tgtcgtttcg ttcattcgtt tagctgctcg gccagttggt gctgcaagta
     7981 gaataggaaa aatttcttgg gtatattttg aaggatccaa ttccagtccg ttcaactctg
     8041 caaaaagatt gacgattccg ttgatcacag tagttttccc cgtacctggt cctcctgtta
     8101 aaataaatag aggggaacgg attgcttcag cgatagcttg ttcttgcgaa ggtccatact
     8161 gtatgccgaa tattttttcg atacgccgaa tattcttctg cacttctttt tcaggataat
     8221 ggatttcttt tttacgactg agaaggcgct ggatcgaatt accgatcccc cattcagaaa
     8281 agtacaaact gttttcgtaa agattagtct cttcttgttg tatctttcct tcttcaacaa
     8341 gttggataat tacagtagca acctgatcag gctggatttc aattgggcga cttgtttcta
     8401 aaatacggat cgtttgctga agcaatgtct ccgccggtac gtatgtatct cctgtttgaa
     8461 ctgcatgctg aaaaatctga tgcaagatag ctgctcgaat tcttctcggt gaatctgctg
     8521 caataccgat ttgttcggct agattatctg cacgtttgaa cccgattcct tctatgtctt
     8581 cgactagctg gtacggattt tcttcgatga tatccaaaga ctcgttctta taggcctggt
     8641 agatactgaa agctaactga ctaccgaacc cgtaacgatt cagtcccatg atcacttgat
     8701 ccatcccgtg gtttagccga atcgtctcag caagcatttc tctttttggc ttcgtcaaac
     8761 cggagatttg ttttaatacc gaaggatcag caatgatttt ttcgatagca tcttctccca
     8821 gcaattctac aattttttct gctgttttct tcccgattcc tgggaatttt tcgctggaaa
     8881 gatacgctac gatcccattt gcagttgttg gcttttcttg ctcatatctt tcgagtttaa
     8941 gctgccttcc gtatttagga tgatccacta attctccata aaaacgataa gtctcatttt
     9001 cttgaatatc gccgaaactt ccggtgacta caatctcttt ttcacggtaa tcagctgtgg
     9061 tttcactgat gtgtaccaaa agcactttgt aaaaattact aggattttga aaaaaaatcg
     9121 cggcaactgt accaacgaaa taaggcattt cttctggctg catcggaagc cgcctccttc
     9181 ttctatagta aaggttctgg tgctgtttca gttcctaaaa aatctgtttg gttccatact
     9241 ttcagttcat atggcaataa tctgcaaggc tcttcagtct ctaaaatcgt caaactacta
     9301 tttaacaatc cacccatttc acgcaactca cttagctctt ttcctgtcat ccattgaatg
     9361 gctgcagtta aagaagctcc atgtcctacg aataaaagtg ggccatcttt atgtcgggca
     9421 accgcatctg ctacaacagt ttcgatacgt gtgattgccg attcaatcgt ttctccgtga
     9481 aaaggagaag gatcatacag atctaaatga ttacgcaaat tcggcagatt atccggatat
     9541 ttctggtaca tttcatcgat cgactgacct tctaaagtac ccagccctag ttctcttagc
     9601 ttatctgtat aaaaaatctc taccggacga gcaagctctt tgttgatacc ttctgctgta
     9661 tcacgtgctc gctttgctgt actggaataa attgctttaa aaggaacata ttttaccttt
     9721 ttcccaaatg ctttgatttc ttcgtaactt tgtggcaaaa gcggagaatc gccattgctc
     9781 ccttgaaaac gtctttcctg attccattgt gtcttcccat gtcgggtaaa atatagttcc
     9841 atacgcagca aactcctgtc tttcttttat tttactctat aataaactgt ctaatccagc
     9901 ttgtcatttt catagtgatg cgtcaattct aaattaggga atccttgctg gcgaagtgct
     9961 tcatacacta tcattgcagc tgtattcgat aaattcaatg agcggacatg ctcatcattc
    10021 atagggatgc gtaaacactt ttcttcgttt tcacgcataa atgtttctgg caaaccggtt
    10081 gtttcttttc caaataaaaa gaagtgctct tctccatcag caaaattttc gtcactatat
    10141 actttatggg caaattttga gatcaaatgt agtttacgat tacctaaaaa tgttaaaaaa
    10201 gcttctaaat tactgtggta agtaatattt acatcattcc aataatccaa ccctgcccgt
    10261 tttagatgtt tgtcatcagt tgaaaaacct agtggctcga ttaaatgaag cggagtattc
    10321 gtggctgcac acgtacgggc aatatttcca gtgtttgcag ggattaatgg ttcaaataaa
    10381 acgatatgat tcatcaggat cattcctctc atatttatgt tcgtttctat tttctgacaa
    10441 tttgattttt gcataaaaaa aaacgtatca actcggtgtc agtcactgcg agtcgttacg
    10501 ttagtgaagc tcttctcact aacttttatc agaacaggaa cctgataaaa accaatgaaa
    10561 aaacaacttg ttgctaatat aacaccctca actttttttt gcaacctcta ctcattaaaa
    10621 actgctagaa aaacgttttc tcttagttcc ttttaataat tctatgtcaa ttgtaatctt
    10681 cttcaaagga ttcttatata agtctgcttt gattcgctct tctacctgcc attctaaagg
    10741 tgacatggcc aaaagatctt tttgattttc ctctggtatc tcaaattcat aggttacacg
    10801 ctgacgttca gttaatttca ttgcttcagc aaacttggct actacacgtt cattggaata
    10861 actctgtttt tcaggttgat tcggataaaa agcctgacgt agttccttta aataattttc
    10921 ttgtggcacc accttcaaca cttctccatc ttctgagagt acacgttgga attcttggta
    10981 atgagaaggc gaaaagatat ttaaaaccgc gttgaatgtt tgatcagcaa acggcaaatt
    11041 ggtcaaatca gctacacacc aaaatgcttc ggcagattgt tctgtagctg cgtagactcc
    11101 ttcttttgaa atatcaaatc caacagcatt ttgaatcttt ttcaattttg aaagttcatt
    11161 caagaagcta ccttctccgc agccaacatc taatagcgag acttcttcag gtaaatgctg
    11221 cgcaatagtc tcaataacgg gctgatacat gccagattgg atcattctac gccttggaac
    11281 gaacattcct tgatcgtatt ctgttttaac cgcatgggat aaaaaataaa gtgttccttt
    11341 tttggaaagg tcaaaacggt gattattttt gcatatcaag ccattatcag acttttttac
    11401 ttcttcttgg caaaccggac agcggaacag ctgatgattt tctgccaaaa actggcgtcc
    11461 tcggtcaatt ttttttaaca tagttccccc tcatttctgt tttatcttac cgttagatgc
    11521 tcactttggc aactgctaaa aatatgatac aatgcctaga agaaagtgaa agataaagga
    11581 gaagattaga tgatcaaaga attttgcgct gaaaactaca catctattcc tctagcaatt
    11641 gctagaggag ccgatcggat cgaattgtgt gacaacttag cggtcggtgg cacaaccccg
    11701 agtactggtg tgatcgaaga aacgttaagt tatgctgggg aaaaagatat ccccgtaatg
    11761 acgattattc gtcctagagg gggcgacttc gtctataacg atatcgaatt gaaaatcatg
    11821 catactgatt tgattgaagc aaagaaatta gggacggatg gcgtagtatt tggttgtctt
    11881 actccttcag gctggctaga cgaagaggcc ttagaactat tgatcgaaac agcagaaggg
    11941 ttgcagatca ccttccatat ggcttttgac agtattcctg aagatcggca attcgaagca
    12001 atcgattggc tggtagaaca tggtgttgac cgtatcttga ctcatggcgg tcctgctgac
    12061 aaaactattg tagaaaattt cccacggctt aaagaattga ttgcctatac agatggccgc
    12121 ttaatcattt tgcctggtgg tggtgtcact gcagagaatg cagcacatgt agctaaagaa
    12181 ttgaacgtaa gcgaagtaca cggaaccaaa atcgtggatc ttcagttata atcttataaa
    12241 caaaaaaaca tttgcaacag gcataatgct tattgcaaat gtttttgttt ttttacataa
    12301 aatagcccat aaataaagaa gcaatattga aataaatcag tacactcgtc aaatcgctca
    12361 aagtcgtgat aaagggaccg cttgctactg ctggatcaaa tcctagacga tccattagca
    12421 tcgggattaa actacctgca agattcgcca ctgtgattgc aaatagcata gccatcccta
    12481 tgacaaaccc caagataaaa ttatgtttcc aaaaacctac gattagaaaa atcgtgatcc
    12541 ccgtaacagc tcctgtgaca acgccggtca agacttcagc caaaacaagt cgaacaaatc
    12601 catgatcttt ctcatcagaa atcgcaagtc gacgaacagc cacagctagc gactgggttc
    12661 cagcattacc ggcagttcct gtaatcagcg aaatgaagac tgctaaaata ctcgcttcac
    12721 ttaccaagtc ttcatagtga ctgattaaag aagcggtcga catacctaaa aacaacagag
    12781 tgatcagcca aggcaaacgt cgagacgctg cctttactgg attttcatta atttcttcca
    12841 cattgacccc ggcaagtcct gaataatcgc tagcagcttc atcatcaata acgtcgatga
    12901 tatcatcgac tgtgacgatt cctaacaaat gatcatcata atcggtaaca ggaagagcta
    12961 agaagtcata atctctaaat gtttgtgcca catcttcttg gtcgtcgcct acatgaactg
    13021 aaagcactcg ttcgctcatc agatcagaaa tcattgcgtc gtcatcattc acgattaggt
    13081 cgcgcagaga aataacccct actagctgac cttcttgatt aacgacatag atgtaataga
    13141 ttgtttcagc tacatctgct tcgttcttca gcacgtacat cgcagagcga acagtttgat
    13201 tggctacgat cgaaacaaat tcagttgtca tgatcgcgcc agccgtttca tcctcgtaat
    13261 ggagaagttc cttgatttca ctggcatcgt ctgccgacat caaacttaaa tatttagcaa
    13321 tttgcttttt atccagcgta ttaagcaagt caacagcatt atctgtatac atctcagaaa
    13381 gcatatcagc tgcatagcta ggacgcattt catctaggta ttctttcata tgttcgttgt
    13441 cttcttcaat cacatcgaac atatccgcta attctttagg cgacagatag gaatagatca
    13501 gctgcctgtt ctcttctgta agagattggt agaattgccc ctgctcatag atatgcatct
    13561 ctaaaaaact gtttctgaat gcctgaatat tattttccct taaatcttga gtcaactggg
    13621 caaatctttc ctctaattct tgattttcat ccaaaccaat ctcacctcgc cttattcttc
    13681 aaaccgtctc acaactgcct ccatgtctgc ggctaaaggc tgcttgaact ccagcaactc
    13741 ttctgtaaat ggatggtaaa aacgcagatc ataacaatga agggcttgtc tttttattcc
    13801 cagatccatt cgcccgccat acatatcatc accgagcagg gcacagccaa ttgcggaaaa
    13861 atgaactctt atttgatgtg tccttcctgt atgcagctgg atatcaacta acgcgatttc
    13921 tgttagtcgc ttctctatcc agtactcagt ctgtgccgaa cgtccttcat cagagaccat
    13981 tcgcttcaat agcgaagaat aatctcgggc gatcggcaaa tcgatatgtc catgtgccga
    14041 taaatctgaa agccttccac tgactaaggc ctgatatttt ttcacaaact tcttttcacg
    14101 aagttgcata tctaattttg cgtgcgcaaa tccatgcttt gcaaaaagca tcaagccaga
    14161 tgtatcccga tctagtcgcg tcaccacatg gattacttgg ttttcgtaac cttgtttttt
    14221 ataataagcc tttacacgat tagccattgt cccatttgga tggtattggg caggaataga
    14281 cgaaacgcct gctggtttat ttactaccag aacgtgttca tcttcataca cgatatcgat
    14341 cggtgtttca tccaaaagta cggtttcatg ttctccttca gcaggaatca caatggttac
    14401 cttatcatcc ttagctagag aaaacaagac attttctact tgatcattaa ctttgatttg
    14461 accgccttga aattttattt tcgctaacag accctttgag atcccttttt cttttaaaaa
    14521 atattttact tgctgagaat gatctttctc ataatcccat gtaaactgca tatcaatcct
    14581 cactaataaa ggcatctttc acacgatgcc aaaaatgcat atgtcgataa gaagcaaaat
    14641 ggatccgttc ttctgctatt cgataataaa ttgagcggat atttgctttt gcgacattca
    14701 attgatcaac cgttacaaga taatcttctg tattttccaa ttttatttct agccattcat
    14761 catgggcaat cacgatcgga gaacccaaag tacgaaacac tcgattattc agtgaagcaa
    14821 tctctgccaa ctgaaaggca ttgatactag gatggatcac agcaccgccg acacttttat
    14881 tatatgctgt cgaaccagta ggcgtagaaa tcgtcaatcc atctcctcta aaactttcaa
    14941 acagctcgtt tttgatgtat acatcggcta ccatcgtacg attggcccgt ttaatcgttg
    15001 attcattcag tgctaaaaaa tgctggtccg gtgtttcatc caaataactg atccgaacat
    15061 ccagcaaggg ataactaaca ctttgttccc ggttcgttcg taagctgtct actagttctt
    15121 ccagctcgta atcccgccaa tccgtgtaaa accctaaatg acctgtatgc acgcccaaga
    15181 aacgcacatc attcagacaa tgactgtagt gatggaacgc cgacaataat gtgccgtctc
    15241 cgccgactga gatgaccaat tctggctcat gatcatctcg ttgaatccct gcttgttcta
    15301 aaagtgcgtt caaacgttct gtcacttcta tagtctttgc ttctttatta tgaacgatcg
    15361 ctactttcat cccctgcctc ctctctttcg ctttctttct tcaaaagcgt tcgatagtag
    15421 acatcatctg attttcctct tccatgggag aataaccgct gtgcttcttg gatttcttca
    15481 cggatactgg acatctcttc atccaactga taggcagctt ctgccgcacg ctgaagtcgt
    15541 tcactcattt cttctggaaa aacgccttga tatttataat tcagcgaatg ctcaatcgtt
    15601 gcccagaaat tcatcgcaag agtccgaatc tggatttccg ccaaaatttt cttctcaccg
    15661 ctgatcagct gtacaggata ctcgatcacc agatgataag aacggtagcc acttgctttt
    15721 ttatttgtga tgtaatctcg ttcttggaga actttcatgt cttttctttt acggatgatc
    15781 tcaacaactt gatggatatc ttctacaaac tgacacatga tccttaaccc ggcaatatca
    15841 gacatttctt cttctaaacg tcccattgga atatgccgta attgtgattt tgttacaata
    15901 ctatcgactg gcttgactct cccagtgaca aattcaatcg ggacatgtcg attttgttca
    15961 cggaactgtt tgcggatccc ccgcagtttc actttcaatt ctgatacagt ttgttcatat
    16021 ggtgctaaaa atgcttccca atctcgttcc atagctgata cctctacttc attaacattc
    16081 attgtttatt ctaccatata tgcaaagttt tttcgtactc ttgatttatg cattgaccaa
    16141 aaaaagaaaa ttaggcaaaa tagacaaaaa ggagtcgatc aaatgacaca aatgcttgaa
    16201 atcgaatata aatctatgct gacaaagcaa gagtacgaga tattcatcgc tcactatcaa
    16261 ttaacagata aagatttccg tgtacagact aatatttatt tcgataccgt tgatgaacag
    16321 ctgaagaaac aaaattgtgg cctacggatc cgtttcgttg gtcatcaagc tgaatataca
    16381 ttaaaaacac ctgctgaaaa agggcgtctc gaaacaacgg atacctttat aacagaagaa
    16441 gcagaagcat ttatcttcga aaaacgtctg cctcgttcag gcgcagtttt tcaaaaactt
    16501 tctgatttga atatcgatcc tgcttcatta atccaaaccg gaaagcttac aacaaaacga
    16561 gctgaattcc ctattgaaga aggactttta gctattgatg aaagctgggg agacaatcta
    16621 cacgattttg aactggaact agaggtaggg gatgcatctg tgggaaaaat tgcttttata
    16681 aattttttaa aacgtttttc tttaccttat cgtcctgcta agaacaagat ccaacgtatg
    16741 cttgaagcta aaaattagaa acctttcatt ttcacaaggc acttgagttc atttttttac
    16801 ttttttctgt taagttatag gatgtgaaag aatctagtca ctagttgtat agaatctatt
    16861 ttgggggaga ttcatatgat cgaaatctat ttatttgtta atcctttagg ggaatactgt
    16921 ttcgaaatgg aacaacagtt attacaattt atcgaagaag agtacgggac accatcaaaa
    16981 gaaaagatgc aatttcgctt tcttcctttg gtcaatttgc agacaattgg ggatgtcatg
    17041 caacaaaaag gaatttctca gaacaatctt gaggaacgta atcacttatt ctcaatgact
    17101 tattctgcag cattggactg caaagcggcg cagtttcaag gaaagaaaaa aggccgccgt
    17161 tttttgatca aattgcaaga agcagtcggc tgtaatgaca taccatattc tcaagaactt
    17221 gctgaatcca tatttgaaga aatcggcggc gatttgaata tgtttaaaga agatcgtcag
    17281 tctgacttcg ttaaagaagt attcttttct gatcaaaaaa ttgctcggga aatgggcatc
    17341 acaaaacacc cttctgcagt cgtttacaat tatgcctgcg accgtgattt tggtgtttta
    17401 gtagaagtaa aaggtacaag tagcctttgg agaatcacag agctgtgtaa aacaacagat
    17461 aactcatatc aagtttttaa tggtgaacat ttacatacaa atgattctca gttccattca
    17521 agaactagcc atttacactt gctttctaat taaaaa
//
LOCUS       DAZAOD010000056        16370 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000056 DAZAOD010000000
VERSION     DAZAOD010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.057"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(112..360)
                     /locus_tag="ACHDPO_001829"
     CDS             complement(112..360)
                     /locus_tag="ACHDPO_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369446.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            359..487
                     /locus_tag="ACHDPO_001830"
     CDS             359..487
                     /locus_tag="ACHDPO_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFN3369447.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            544..2238
                     /locus_tag="ACHDPO_001831"
     CDS             544..2238
                     /locus_tag="ACHDPO_001831"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFN3369448.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            2338..2511
                     /locus_tag="ACHDPO_001832"
     CDS             2338..2511
                     /locus_tag="ACHDPO_001832"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369449.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            2889..4022
                     /locus_tag="ACHDPO_001833"
     CDS             2889..4022
                     /locus_tag="ACHDPO_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFN3369450.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            4053..4373
                     /locus_tag="ACHDPO_001834"
     CDS             4053..4373
                     /locus_tag="ACHDPO_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFN3369451.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(4402..4866)
                     /locus_tag="ACHDPO_001835"
     CDS             complement(4402..4866)
                     /locus_tag="ACHDPO_001835"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3369452.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(4998..6251)
                     /locus_tag="ACHDPO_001836"
     CDS             complement(4998..6251)
                     /locus_tag="ACHDPO_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFN3369453.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(6280..6597)
                     /locus_tag="ACHDPO_001837"
     CDS             complement(6280..6597)
                     /locus_tag="ACHDPO_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFN3369454.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(6623..6943)
                     /locus_tag="ACHDPO_001838"
     CDS             complement(6623..6943)
                     /locus_tag="ACHDPO_001838"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3369455.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(7407..8822)
                     /locus_tag="ACHDPO_001839"
     CDS             complement(7407..8822)
                     /locus_tag="ACHDPO_001839"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFN3369456.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(8839..10155)
                     /locus_tag="ACHDPO_001840"
     CDS             complement(8839..10155)
                     /locus_tag="ACHDPO_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFN3369457.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(10305..11003)
                     /locus_tag="ACHDPO_001841"
     CDS             complement(10305..11003)
                     /locus_tag="ACHDPO_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFN3369458.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(11292..12281)
                     /locus_tag="ACHDPO_001842"
     CDS             complement(11292..12281)
                     /locus_tag="ACHDPO_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFN3369459.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(12361..13194)
                     /gene="msrA"
                     /locus_tag="ACHDPO_001843"
     CDS             complement(12361..13194)
                     /gene="msrA"
                     /locus_tag="ACHDPO_001843"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFN3369460.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(13369..15003)
                     /locus_tag="ACHDPO_001844"
     CDS             complement(13369..15003)
                     /locus_tag="ACHDPO_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFN3369461.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(14990..16366)
                     /locus_tag="ACHDPO_001845"
     CDS             complement(14990..16366)
                     /locus_tag="ACHDPO_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369462.1"
                     /translation="MLISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEA
                     IALTIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLF
                     LSKQIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSI
                     SDSIIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFP
                     WFLFQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVT
                     SIAAKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVK
                     VGESWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLV
                     NVDVNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKE
                     INKKNENK"
BASE COUNT         5138 a         3252 c         2748 g         5232 t
ORIGIN      
        1 gttctaatga taacggttcg cttaaatttt tctttttcac tctcccattt ttctccctcc
       61 atccataaat cgtggaagta tccaaaacaa cgtagcaagt taaaataagg cttagtccgt
      121 catcagcttt tcaaagaagc actgtctcgg tgcttttttt gtacccaaat ttctaaaaat
      181 agaaccatac acctcctcaa atcttttctt cttacctacc ctatttttat ttacaggaaa
      241 atcagacact tcttcttttt tgtcaaaatt tcctttttct tctcgtccta tcatttggca
      301 ttctaataaa aacgaactat ccttggatat agaaagagaa aacaaggagg cgtttttcat
      361 gagtaaaaaa ttaatcaaag tcggcatcgg tttaggtttg cttgcccttg gcgctgcata
      421 tctaggaaaa aagacaggac tattcgaaga tgacagtcat ttatatgatg aattcgaatc
      481 aatctagcat cctatttagt tgaatcacta cggacatact tggaagacat tggaggaatc
      541 acaatgagaa aaagtaaagc aataatgatt ggtgccggta ttgccaatat ggcagcggct
      601 gtttatttga ttcaagaagg caaatggaaa ggggatcaga tcacctttta ttcattggat
      661 gatcacggtt caaatgatgg tgcaccgacc gacactgtag tggatgaata ttggaataaa
      721 aaccatccat tagaaaacca aaaaggctat attgctcgag gcggtcgcat gcttaattac
      781 cgtacctatg tagatttgat ggatctgtta agtcgaatac cttctgttac tgagccaggg
      841 atgactgctg aagaagatac gagagatttt gatgcaaaac accgaacctt tgacaaagca
      901 cgtttgatgg aaggtggcaa aggaatcatt gatggcggaa aactgggatt caataataaa
      961 gaccgtattc ttctgactaa actgattgct atgcctgatt cagaagaaga aaaactagac
     1021 aatatcacta tcgaagaata tttcaaagat gatccacact tttttgaaac aaacttctgg
     1081 tttatgtggg aaacaacatt tgctttcaga acacgtagtt ctgctcaaga attgcgtcgc
     1141 tatatgcatc aaatgattta tgaattcact caaatcgaac atctagtggg cgtcaatcga
     1201 acacgttaca atcaatacga aagtattatg cttcctttga tcgagtactt gaaagaacaa
     1261 ggatgcaaaa tcattttgaa ccgccgtgtc actgactggg aattcaaaga aacaccgatg
     1321 caagatgaaa tcactgtgac tggtttgaaa attaccaata cactgactca agaagaagaa
     1381 tacgttgtgg tcgatgaaga tacagcagtt attttcacta atgggtccat tacagattca
     1441 gctactttag gagattacga aacaccagct gtagaaaata tggattatgg tgcagcttct
     1501 agtctctgga aaaaagccag tgaacgtttc tacaacttgg gaaatcctga caaattcttt
     1561 gctgatcgag atgcaagcga atgggtcagc tttaccctga cgacgaaaaa ccatttgttg
     1621 ttgaatgaaa tcacccgtat cacgactcaa gaaccaggaa atgccttgaa ttcatttatt
     1681 tcaaccacac cgatcacgcc gttaggccaa aaagatgtca atatgtctat tgtcgtgcat
     1741 catcaaccgc attttacgtc tcagaaacca aatgaaacag ttatttgggg ttatttcctt
     1801 tatccaagac gacgtggcga atttgtggat aaacagtata ttaaaatgaa tggaaaagaa
     1861 atgctagaag aactgattgg acaactttca aaagtagatc ctggaccagt gaatattcgt
     1921 gaaaaagaaa cagaaatttt cgacagcgta ataaataata tccctgtcta tatgccttat
     1981 gcttccgcgt tgttcaataa tcgtgccaaa agcgatcgac caaaagtcat tcctaaacat
     2041 tcgaccaatc tggcctttac aggagaattt gtcgagcagc cttatcagat gatctttact
     2101 gaacaaagtg ctgtacgttc tggagaaatc gctgctttcc attttgcggg tattcctatg
     2161 tcccgtcttg tcaaaacacc gcgttacgac aaagatattc ctactctagc tcgtgccgca
     2221 aaaaaaatgt ttgaataatc aagaggttgt gaaaaagctg ccctgcatca agtaataaga
     2281 acaaccaggc taaaacagct tcttatgttt ttgatttggt tggacttatt accgcagatg
     2341 caagcttttg aacaccgttt accaagaggt tatgaaaaag ctgccctgca tcaagtaata
     2401 agagcagcca agctaaaaca gcttcttatg tttttgactt ggttagactt attaccgcag
     2461 atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aaggcgttta gtttcgagta
     2521 tgaagaaaaa ttttgtgaaa atggttcctc acgtttttgc ataaatttga cttaataccg
     2581 agaaactgat cccttctgtc ataacctctt tttatttatg tctgtttctt tttgaaaaca
     2641 actatttttt caacgtttac tctcttgcca atccaacatc atctaacgga tacaactatt
     2701 tcaatgatta ccattacact aaaaaatcgg aaacacacct ctccgaacac aaatacataa
     2761 gactatagaa tgtttcattt aagaaaaaaa gcgtttcatt atcaaaaagg taagatctcc
     2821 tttaaaatga aattatctgt agtactaata atgcagacaa ttttatgaat ctgaaaggag
     2881 catctccaat gaaagcagtc acttggcaag gaaaacagaa aatggaaatc agaaacgtag
     2941 atgatccaaa aatattagaa ccaacagatg caatcatccg tatcacagca acagccattt
     3001 gcggctccga tctgcatctt taccatcatg gtgaagcagt tttggaaaaa gggtatgttg
     3061 taggacacga accaatggga atcgttgaag aagtgggatc tcaagttcaa acattgaaaa
     3121 aagggcaacg tgtggttatc ccttttaata ttagttgtgg tcattgtcat ttctgcctga
     3181 atcacatgga aagccaatgt gatgaatcaa atccagatca gttatatggc gggcttttcg
     3241 gatttggcaa gttgaacggt aatcattggg gtggtcaagc ggaatatcta agagttcctt
     3301 atgcagactc tacttcattt gttgtaccag ataatgatct tcctgatgaa aaagttttat
     3361 ttctatcaga tattttgccc acagcttatt ggagcgttga aaacgcagga gtaaaaaaag
     3421 gcgatacagt tgtgattcta ggttctggtc cagtcggtct attcgctcaa aaattcgctg
     3481 ttatggctgg agcagagcgc gtaatcgcag tagatccagt acagcaccgt ctagataaag
     3541 cggctaatta caatggggtt gaaacttatt tcttagaaga cacggcacaa gctggaacag
     3601 aattgtatga actggctaaa ggtggcgcag atgtcattat cgattgtgta ggaatggacg
     3661 gattagagcc tgtcaaagaa aaagcgaaaa atttagtaag cttacaaagc ggcacaatct
     3721 ctccattaca gatggcatcg caagctgtca aaaaatttgg aacagtccaa gtaactggtg
     3781 tttatatgac tccagcttct tcttacccgc tgcaagaatt ttttatgcgg gatatcgctg
     3841 tcaagcatgg acaggcacca attatccatc taatgccaaa aatttacgca atgattgcag
     3901 aaggactatt cgatcctaca caaatcatta ctcattcgct gccactatca gaagcagcac
     3961 aagcatatga gatctttgac aaaaaagaag ataaaaatat aaaagttgtt ttgaaacctt
     4021 gaattcagta aaaaatacag gtgattttct ttatgcccaa aatcaaacga aatacccatg
     4081 agatcgaaat aggaaaagaa gaagatatcg aaatacgagg acgtcgcttc cgcttctatt
     4141 tccaaaatcg ttacacattg atctcactgg ctgtcgattt attaaccggg attttctata
     4201 tttttggaag ccttgcttcc ttaactaaaa tccccgatcg atatggcacc tatttttatt
     4261 tggctggtgc tattttcttg acgattcgtc ctattctcag aatcgtaagg aacattttta
     4321 tttacgacga aaaaaaagca atgaagagaa caagcaaaaa aaaagaggca tgagaatttt
     4381 tcaaatctca tgcctctttt ttcaccctat cgtatcactt tgatacagac gagcggtcgt
     4441 cccactttct tccttgacca ttgtcaaaaa tgtccactcg tatcgttcat aaaacgtggt
     4501 atgatctgta attaagtaaa gtttttcgta cccaagttga tgcatttctt ttctgatttc
     4561 cgctaatatc cgcttggcta tcccctgctt acgcttttcc ggttcaacaa acagggcaca
     4621 aagatttggt gtcagatcag ggcggttatg gaagtcgttt tcaatgacgc ccgctcctcc
     4681 gacgatggtt tctttttcat ctaagaccac ataccattga ggaatacttt ccttattagc
     4741 gattccagta cgaatacttt cctcatacac aacagcagga actccccatt ttgatgaaaa
     4801 ccaattcgcg ctttgtttta ctaattctgg gtgttctctt aatttgatcc agttatatgt
     4861 aaccaatgtt taaacctccg actaaaataa aacgtttaca aaaattatac aagtctttat
     4921 gaaaattagc aatgacaaca atagtgatgt aaaaaaaaaa acggaaaaca atcacttgtt
     4981 ctccgttttt tgattaatca agcatctaaa gcttcttttc ttctttcttg gatcgtagct
     5041 accttgacga acggtagata gatcaaaata gaaagaacca aattgacagc ggctagtaca
     5101 ccacctgcaa tactttttgt tgccaataca ccgccaataa ttggtggagt tacccatgga
     5161 ggcataacgg tagctgctgg cactaaacct gtagaagtcg caaagtaagc aacactaact
     5221 aagaccattg gtgtcaaaat aaatggaatg aacatgatcg ggttcaacac gataggtaac
     5281 ccaaacatcg ttggttcatt aatattgaag acacctggcg caatcgacaa gtttgttaca
     5341 accatatatg gtttgttttt acgtcctact aaataaatag ctaacagtaa acctaaagtt
     5401 gcacctgttc ctcctaagtt gacaaagctg tcaaagaaag gtttgttcac gataaacggt
     5461 gcgctatgtc cagctgcgat tgcattaacg tttgcttcaa tggctggcgc attgattgtt
     5521 tgcatcaaag gatcgaccat attcgctccg tgtaaaccaa agaaccataa gaatggtgtg
     5581 ataaatgcaa gcagtaaggc agatggataa gagtttgcaa gtcccataaa tggttcttgg
     5641 accactgtat agaaagaacc tacgatatca tcaacaccga atgcagcaaa aattgcagca
     5701 actaaagcaa acgcagagat agtgatcatt gctggtagta atgaagcaaa tgcttttgca
     5761 actgccggtg gcacaccatc aggcattttg atgatcaatt tttcatttcc gcttaaacgt
     5821 acaaagattt ctgttgaaat aatcccaaca ataatagcaa taaacaaacc gtttgagctc
     5881 atacctaatg ctccgcctaa agcgaagaaa gagcctaaag aaatcacacc tgcggaaaca
     5941 ccgtcttttc ggtagccgtt agctaaatga taagcaagca agaaagcaat caagacagaa
     6001 agaatggcaa atgtaccgtt ccaagcagca gccccgaatc ctttccatga ttcaccacca
     6061 aaaattgagt tcatcaattc ttggaacccg ggaatcggta agttattgat cattactgct
     6121 aatgctccta agatcattaa cggcatactc accataaatg agtcccgaat cgcaactaaa
     6181 tgccgttgtg caccaatttt tgatgctaca ggtataaaat gtttctccat aaatgcaaca
     6241 aatttatcca taaatcttcc ctcttttctt tactgtagat tacgcgttca atcgacgata
     6301 cagatcaatg atctcttttg ctaaatctgt aaaagctata gatgtcatca gatgatcttg
     6361 actgtggacc gtcaaaagcg tgacttcaac gtgatttcct tgtgcttctt gtgtcagcat
     6421 ctctgtttga gagtgatgtg cttggactaa agattcctct gcatctttga ttttttcatc
     6481 tgctaaagtg aaatcacctt ttttcgcagc agcaatcgct tccattgcat cgctttttgc
     6541 atttccgcca aacatgatca gacccatgat ggcttctaga tttttttgat cttccattta
     6601 ttgtatcctc cgataatttt tattatttgt ttattagttt ttctgcttgg tcgagtactt
     6661 tttcaccatt catcatgcca tagtcagcca tattgattac atctaaagga atgcctttag
     6721 gtgctagctt ttcagcaaat tgattttgca taaagcgtac ttgcggtcct aaaagtaaaa
     6781 cgtctacatt tttagattct agttgattat ccgcatctga agcagataca gcaaagatgt
     6841 ctgcttccat tccttttgct tctgctgcct tttgcatttt tgtgactagg agacttgtac
     6901 tcattccagc tgaacataca agcatgattg ttttcttttc cattttaaac acgttccttt
     6961 ctatacttac acttgtatat aagcaagtag cgtgccaact ttaaaagcgc tttaaaaagt
     7021 tgatatcatc acatttaagg tctataccaa gttgcataca cactaaaaaa gaaagcgcac
     7081 actaaacaca caaattaatt tttattacct tttttctttt aacgtgcaca aaaaaagttg
     7141 tgacacaaaa cttgtcacaa cttttttcaa ataaacggta ttcaaaagct tgcatctgcg
     7201 gtaataagtc caaccaagtt aaaaacataa gatgttgttt ttactttgct attcttatta
     7261 cttgatgcag gacagctttt tcacaacctc tcaataaacg gtgttcaatc agctgaccct
     7321 gggtattagc tcaaaacgct ggattcacaa cctcttttat ttcaaataac cagtaaatac
     7381 aatgaacatc tacaaaaaac ttctatttat ttatagattt cgtcaggcaa atccaattct
     7441 ctcttatcaa tcaaagtctg ataccacgaa gcagattttt tcaatgttct gcttcgttca
     7501 tcgttcaatt cgattcgaac taatccatat cgattcttaa atgcattcat tggtgacaca
     7561 cagtcagtga atgcccataa catatagcct tcgcaatttg cgccttcttc tgttgctttg
     7621 atcaagtaat gcaaatgctg tccgataaat tcgatacggt aatcatcttg cacgattcct
     7681 ttctcatcca tatactgttc ttcatattct cttcccatac cgttttctgt tatcagccaa
     7741 gggatattat gataattttc ttttagatac atggctatat catacatgat tttcggatag
     7801 atttcccatc ccctggaatt attcattttc ttcccaggta aatcaaagac ttcataatat
     7861 cgttcaggat ggaaaggtgt ctcttcattc cattgataac gaggggcgcg aacgcgttta
     7921 ggataatatt gattgattcc aaggaaatct actgtatgat gctgaatcgt ttctaaatcc
     7981 tctgttgcag gatcgaaata aatcgattgt ttttgacaca actccaggaa ctcttctgtg
     8041 tagtatcctt ttaccatcgg atcaaaaaat actcgattat aaaacaaatc atacatataa
     8101 gcagcttttt ggtcttctgg agaattggat cgagcataga ccatttcagg atttaaaata
     8161 cagccaatcc ttccaccata atttccgctg cggtaaatct ctactgcttt agccgttgct
     8221 aaaactttat gataattcca catcatccac ttttttgtgt tttgttcatg cggccagcga
     8281 acagcatcca aatagcaacg cgtttgggga acgattggtt cgttgaatgt aaaccagttt
     8341 tttaccctat caccgtaacg atcaaaggca atttgagcat acttagcata aaaatcaact
     8401 acttttcttg aagaccagcc atcatatttt tccaaaagaa aagctgggac ttcataatgt
     8461 tccaaacaaa tcatcggttc tacgtctgct tcgatcaaag agtcgatcat ttcacttata
     8521 tgctgagcat attcttcatc tactatacag ttctcataat cagtaaaaaa acgagcccaa
     8581 ttgatagaag tccgataatg tgtcagatgg atggatttca tcagatccac atcctgctgg
     8641 tattgttcca taaaattagt tgctacggct gggccatacc cattatgcca aacaaaatgt
     8701 tcatttttat accagctatc tataaacgaa tcctgtcctt ctttttttcc tttccaacct
     8761 tccgtttgcc aagcagaaga tgcagcacca agaataaaat tttttggaat agtaattttc
     8821 atgatttcct cctgtttttt agatcccatc attttccaca cgatttgcta cttttacaaa
     8881 tggcagatag atcaaaatag aaacaataat acaaacaagt tgcgtaataa ctgcaccgat
     8941 atttcctgct gttgccagat aagcattgac gatcggcggc attggccaag ggaccattac
     9001 aactgctttc gccgcaaatc ctaaagcggt tgcaaaataa ccaatcgttc cagtgataag
     9061 aggcgttaag ataaacggaa tagctaaaat tggattcagc atgatcggca taccaaaaat
     9121 aactggttca ttgatgttga agatcccagg agcaagggat aacttggtga tttgtttcat
     9181 atcttcccgt tttccaacta acaatactgc aatcagtaaa ccgatcgtga ctccagaccc
     9241 gcccatactc atatacatat cccaaaatgg catagtaata atgttcggta cttcttttcc
     9301 agcttcaaaa gcttccgtat ttacagcaat tgccgctaaa agcaacggtt cccgtatcgg
     9361 cttcaccatt tgatttccat ggataccaat cacccaaaag acttgcgcaa taaacatcaa
     9421 tagcaaaata cccggtaacc cttgtacgac accttctaat gggcgttgta cgacattgta
     9481 aatgatatca taaaggtaca ttcctgtaag ttctttgatg ataaatcccg cagccgcgat
     9541 acccgataca gtcagaatcg tcgggaataa agcagaaaaa ctagcagaaa cattcgttgg
     9601 cacggtatca ggcattctca gctgtagttt cttctgtttc ctcaaccagc aataaagttc
     9661 aatagaaagg atggagacca acattcccaa aaataaccct ttcgtatctg tatattgttt
     9721 agccaatacg ttttctacta taacagtctg attttcattc actaattcat aaacagttgg
     9781 attaacagat aaataagaca tcactgcgat gataccaggg aatacaccat ccactttatt
     9841 cagcttggct aattcgatcc ctatcagaaa aacagcatag atggtcaaga aacttagtgt
     9901 gacatagctg atggcagatg cgataggctt taattcttct aaaaaacgca agaaacttat
     9961 ctgtgctaag ccattttccg agtcaaagac cattgctgaa aacaatgtgc caaaagcacc
    10021 cgtaataatt accggaatca atgcagcaaa tgcgtttttt atcaccatga tataccttaa
    10081 attattgatt ctcgttgcca cgttccctaa aacattggct aatttatcca taaaactcat
    10141 tccagatccc ctcattcctg cttcttctcc ttgacgtcat ctctttttgt ctattagtca
    10201 gcgcttacat ttcgatgaac agaaactatt tactcctctt ttttaccaaa tataaaacaa
    10261 aaattcatct gatgtattta tcataaaata catcagatga actgtcaatt agtttctttt
    10321 tctcctatta ttttctgtaa ttctctccga tttattgcca tatggacagt cattgcatca
    10381 aacgcagcaa gtgcattccg cctttcgatg gcctgaacga tctctgtatg aatatcgatc
    10441 gtctcgattt tcagatgctg gatatcataa tttttattaa acaaagcaat tgattcatta
    10501 atgattggga taatatgcag caaggctacg tttccgctag cttctgcaat catcgtatga
    10561 aaatcgatgt ctaattgaac atgttcttgt gtgccttctc gaaaagaagt ttcaatcttt
    10621 tgcgttaatt ttttcatttg gacgatttga ttcttcgttg catattccgc tgccaaacct
    10681 gccatcttag gctccaataa atatctcagt tcaaataagt ctcgtatcat ccgatcctga
    10741 tcttcaatca aagaaaaacc gagtgggtca ttggcaatcc ctcgcttatc actgacaaat
    10801 gtccccgctc cttgccgaac ttcaaggata ttcctggaag ctagagcccg cacagcttct
    10861 cgcaccgtgc ttcgccccac ctctaaataa tcggacaatt catattcatt cggcagttta
    10921 tctcctactt gcaactgcat ttcctttaaa tatctaagga tcttgtcagt agttacttct
    10981 actagggttt tattttcttc caaaccacat acctcctttt catctgatgt attttttcgt
    11041 aattattata acacgtttga atcatctgat gattttttgt atacaaaatt gattaatccg
    11101 ttcatagaca tacaaacgaa gaagatattt accataaaaa agactaggat aaaattcact
    11161 cctagccttc gatcattttt attttgaacg acaaaaaata tgatgttcaa taacagacga
    11221 tcttcattcg attcttgatg tcatcttttg ttttttttaa tatatggata aaaagtttga
    11281 ttacatcgtt tctattctag aatttggtcg attctcaatt cttcttctgg tgagaaatct
    11341 aaattatcca tcattcgaac actttcttgt aactgactta accgacttgc tccgaccagt
    11401 acacttgtaa cagatttttg tcgcaaattc catgcaaggg ccatttgcgc taatgattgt
    11461 cctcgtgata cggcgattgt ttgcagtgct ttgatttttt ccagagttga tccaacttgt
    11521 tcttctgaaa ggaatggtat ttccttacga tgtgctctag aatcttcagg aataccatgt
    11581 agataacgat ttgtcagcaa cccttgagca agcggactga acgtgattgc ccctagccct
    11641 tcttcttcta atactggaga tagatcgtct tctagtagtg cacgagaaaa catattgtag
    11701 cgcatctgat gaataatgaa cggtgcttcc tttcttttta aaatttcagt catttttttt
    11761 gtatcttctc cattatagtt ggatatacca atatataatg cttttccttg tcttacaagt
    11821 tgcatcaaag cttctgctgt ttcttccaaa ggtgtatcag ggtctgggcg atgatgatag
    11881 aagatgtcaa cataatctag ccccattctt tggagacttt ggtcacaact tgaaatgatg
    11941 gatttacgag agccccattc cccatatggc ccttcccaca tatgataacc tgctttgcta
    12001 gaaataatca gttcatcacg gtaggcttga aaatcttctc taaaaatacg cccaaagttt
    12061 ttctctgcag ctccagcagg gcctccataa ttattcgcaa ggtcgaaatg ggtaattccc
    12121 atgtcgaatg cgcctcttaa aatctctctt tgattatgga taggatcata atcaccaaaa
    12181 ttttgccata atccgagaga taaaatcggt aatttcaaac ctgaatgacc ggatttacga
    12241 tattccattt tttcataacg tgcactatct gcaatataca atttttctcc tcctcatcaa
    12301 atctttttaa aacgctttct tttttctatt tttagtttac tacattttaa agaaaaggag
    12361 ttaatcaaaa tgattttttc gtatattttt ttgccatttg ttttttactc gttgatagat
    12421 cagaaattga ttacgtgctt gctggatttt tttataacgt ttcggttgtt ttttgtaaaa
    12481 ttgctgatga tagttttctg ctggccaaaa cgtaccggct ggttcgattt ttgtgacgat
    12541 tggttggtgg aaagttcctg aactgtctag tttctgtttt gattgttccg ctaattcttt
    12601 ttgtcgttcg acttgataaa aaatcactgg acgatattgc ttccctctat cttgaaattg
    12661 tccaaatgta tctgtgggat cagtaatttg ccaatagatt gtcagcaact cgctataact
    12721 tatttctctt gtgtcataaa tgatctccac agcttccaca tgacctgtgt aaccaccact
    12781 tacttgatca taatttggtt tttcaacatg tccgcccgtg tatcctgaca aaacagatag
    12841 gatccctttt ttcgattcaa acggctcgac catacaccag aaacatcccc ctgcaaatac
    12901 tgcacgttct tgatagtcag catcttgcat ggcatgcttg gaaaagtcat atttttgctc
    12961 cttatcaaat ccttccgtaa tcaataaata aaagtccatt acatcaggcg tcagattcat
    13021 tcggatagct aatggacgta gtgttgcttc tagttttgat aactgttctt taacggatat
    13081 attttctctt atgtcattct ttgtctgaat caatactttt cgttcccaat ctcgtgtatt
    13141 cggattcaaa atcagattat aaagtgtttg aatgaatatt tgttcctcat ccatagattc
    13201 tcctcctttc cgaagaagac aagctagtga ctttagctgt aatttatcat aaagtgagga
    13261 aataagcgat tacttcatcc ccctacagat ttttcgtata aaaaagagag aatccttatc
    13321 gacagattct cctttttaat caatttattt tataaatgaa aagttaattt accttttatg
    13381 gaaaactatt ttaaaaaata aacataaata tgcagttaat gtaacaagat aagaaataat
    13441 agtcgttact gtataacttg tgcttacttt aatatcagca actcctttga ctccgcttat
    13501 ttgtaccaat ccattagcat tcacctgctc ctttacaggt tgatgattta tttctacatt
    13561 cgttcctaaa taagcatata caggaagtgt gattacttgg ctcttctcat tagttactct
    13621 atatatgata gaactaccag ttgttttata aggaaggttt acccattgac tgccaatctt
    13681 tgcttcgtgt tttattatat gctccttatt ctccaatgaa gcgataggag aataatcata
    13741 taaaaaataa tccattcctt tagtggtata cgcctctact gtttctttgt ttacaacaat
    13801 atgtcccggc tgagaaatta ttttttgatt gaaatttttt ttactagaaa cagttaaagt
    13861 gattaataac aaaacagtca taaataaata aaatagttct cttgtcttat tgtatcttct
    13921 atttttgaaa aatatcatcg ttaatatcag agaagagaat attatttgca agcttaagat
    13981 ccgccaagga aattgtaaca atttggctgg cgtattttgc agaagatacc atggcaccaa
    14041 actagttgta gctagccaag tcaaacacgt accataataa atcttttttt ctatgtttgt
    14101 taatttttta aataaaatca ggggaataca taaagataac agaccaacta gtcccattga
    14161 gtaagtagtt aagtcgttgt tcatagcttc agtcagacta tcgaacacat tagatgcatg
    14221 agcatataaa tttgtcacgc taggtttgtt gattttttgg tagagcattt gttcaaacat
    14281 cggataccaa aaagcactcg tcagaaccaa tgtcattcct gccgcactaa ataatttttt
    14341 aaatatagca ataaaatctg cattcttgaa acctttagaa accaaacgaa taaaaataaa
    14401 aatgataatt aatgctgtac tcattaatgt tgatagtaca tggctgtaca ctagcaaact
    14461 catactcaat gctagcttta cagacggata cttttcttct tttccagaga tgatttgata
    14521 agcataaaat aatacaggga taacaagtgt tattgcgata gcttcggcaa ttgcggaacg
    14581 atagtagatg tctactgtcc gataagcaga gaaaatatag agacaactaa ataaaaatgc
    14641 cgcttttttt tgttttaaaa accgctcgcc ataatgataa gctacgagtg ttgtacacaa
    14701 gttcaataac caaacgtaaa taatatagct tacaatcaaa ttttttgtca tccaatataa
    14761 cattacagct ggaaaaaaag tcagaaaggg ataaaaataa tttacaccat atccagtata
    14821 attgaatgtc tcataattaa tcggactggt aaaaatagtc gataacccct tgattcgaga
    14881 taagtgaaaa gaaagatctc cagtggtata aatactctgt gtatttttga aaaagatgaa
    14941 agaatatata ctactaacta taattaatcc actcaatatt actacttttt tatttatttt
    15001 cattcttctt gtttatctcc tttttagtca catatcgaga atctttcaac ttattaggtg
    15061 caaatcgttt aaaacttgaa tacaccacta aacaataagt cagaatactg atccataaag
    15121 ccatgagagc agttggagta tattttgttg taatttctat cttattttct ccagcattta
    15181 catccacatt cactaagcca tgttttttat aagagtcatt tacgacttta ccgtttactt
    15241 ttacctgtgt acctaaataa gcatatactg gtactgtcac tttttgcttt ttgttgcttg
    15301 ccactgtgta agtaatgtta ttatctgcag ctttatactt ccctttttcc cacgattctc
    15361 ctacttttac ttcatgtttt tctaagtgag gcctttcttt tatcgcttct gttggggcgt
    15421 aatcgtataa tcctcccata tctgatgttg tataacgtgg gagtgtttct tcattgataa
    15481 caatatgacc gtgttttgat tggataactt ttgcgtaatt ttcttttgct gctatagacg
    15541 tgacgagtag aaacaccaca gtagcgccaa tgattaacca tgaatatttt ttattcatag
    15601 tctttttcat aaaaacaagc gttatgatca ttgaagaaaa aaagatttgg atacctaaga
    15661 tacgccaagg aaactggagt aagcttatcg gtgttttttg aaacaaaaac catggaaata
    15721 aattagttac gcatacccat gtagaaacta cgccaacata gatgattttt tcttttttct
    15781 ccatttcttt cagtatgaat aaaggaaaaa tcaacgcaac caatcctaat aaccccatag
    15841 tgtatgttgt aatatcgtta tttaacgctt gaatgatact atctgaaata gaaagtgctt
    15901 ctagctgcaa atctgttttg aagggactgt gtatttcttg ataattcatc tgctgcaaca
    15961 taggatacca aaaatagcta gttaatgcac aagtcaaaaa aacagccttt actaaattca
    16021 cgaccacaaa ttttatatcg ttttttattt gcttgcttaa aaacaaacga actataatca
    16081 tacaagcaat caatgcacta cacaatagtg tagttaagac atgagtatac acaagtagac
    16141 ttatactgac agataaagcg atgacttttt tttctctatt gaatatcaat ccataagcat
    16201 aatataaaac agctgggata atcgtaagag cgattgcttc tgcaattgcg gatcgataat
    16261 agatatcaac tgttcgataa gttgcaaaag tatataaaca actaaataaa aaagcagcat
    16321 ctatcttttt aaaaaacttt tctccataat aaaaactaat cagaatcgta
//
LOCUS       DAZAOD010000057        16132 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000057 DAZAOD010000000
VERSION     DAZAOD010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.058"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(536..721)
                     /locus_tag="ACHDPO_001846"
     CDS             complement(536..721)
                     /locus_tag="ACHDPO_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369463.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(1571..1912)
                     /locus_tag="ACHDPO_001847"
     CDS             complement(1571..1912)
                     /locus_tag="ACHDPO_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFN3369464.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(1912..2142)
                     /locus_tag="ACHDPO_001848"
     CDS             complement(1912..2142)
                     /locus_tag="ACHDPO_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFN3369465.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            2429..2767
                     /locus_tag="ACHDPO_001849"
     CDS             2429..2767
                     /locus_tag="ACHDPO_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369466.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(2972..3534)
                     /locus_tag="ACHDPO_001850"
                     /pseudo
     CDS             complement(2972..3534)
                     /locus_tag="ACHDPO_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(4266..4847)
                     /locus_tag="ACHDPO_001851"
     CDS             complement(4266..4847)
                     /locus_tag="ACHDPO_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3369467.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(5030..5656)
                     /locus_tag="ACHDPO_001852"
     CDS             complement(5030..5656)
                     /locus_tag="ACHDPO_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFN3369468.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(5678..7009)
                     /locus_tag="ACHDPO_001853"
     CDS             complement(5678..7009)
                     /locus_tag="ACHDPO_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFN3369469.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(7164..7565)
                     /locus_tag="ACHDPO_001854"
     CDS             complement(7164..7565)
                     /locus_tag="ACHDPO_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFN3369470.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(7651..7857)
                     /locus_tag="ACHDPO_001855"
     CDS             complement(7651..7857)
                     /locus_tag="ACHDPO_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369471.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(7952..9454)
                     /locus_tag="ACHDPO_001856"
     CDS             complement(7952..9454)
                     /locus_tag="ACHDPO_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFN3369472.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(9472..9927)
                     /gene="argR"
                     /locus_tag="ACHDPO_001857"
     CDS             complement(9472..9927)
                     /gene="argR"
                     /locus_tag="ACHDPO_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFN3369473.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(10025..10642)
                     /locus_tag="ACHDPO_001858"
     CDS             complement(10025..10642)
                     /locus_tag="ACHDPO_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFN3369474.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            10863..12236
                     /locus_tag="ACHDPO_001859"
     CDS             10863..12236
                     /locus_tag="ACHDPO_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3369475.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            12311..13423
                     /locus_tag="ACHDPO_001860"
     CDS             12311..13423
                     /locus_tag="ACHDPO_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFN3369476.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(13495..15132)
                     /locus_tag="ACHDPO_001861"
     CDS             complement(13495..15132)
                     /locus_tag="ACHDPO_001861"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFN3369477.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(15300..15908)
                     /locus_tag="ACHDPO_001862"
     CDS             complement(15300..15908)
                     /locus_tag="ACHDPO_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFN3369478.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         4512 a         3297 c         2777 g         5546 t
ORIGIN      
        1 ttttatagaa tagaactagt gttgttttca tagactctcc tttcttcata tttccaatta
       61 atcacaaatt cacggcatta ctagaaaaat taaaggggcg cagaagtgga aaaatactct
      121 tcgactttcc ctacaaacca ggccatcttg tgtttaataa ctataccaaa tctaaggtac
      181 ctctaaatct aaattccatt tgtggcggtg acctccaatt tttaactctt ctatctccca
      241 tccagtatac ataaccttga tacttcgacc acttatatat cgaacacaca aatacctatc
      301 cattgcagga gtactaccta acttagttgc tacttgcatc taaataacag ctgaaaagat
      361 aggacttact cttagtaaag tatctgaact attaattttt aaactatcat ttttatcctc
      421 aactacatgc acatctgttg caacttcact ttctgtctca tccagataaa tgattaagga
      481 atcgggaatt gcaatatctt cagctgacgc tggaatagtt gagctaaatt agtcatcata
      541 tctttattat aaaataacca acagcaaaaa atacaatgaa aaacaaactt ggaactaatg
      601 tatcattaat aaatgttgaa aaattcagca actcattact gtatgatttt agcagcccaa
      661 ccaacatata ccctataaaa gctaataaga tggttaggaa tcctttagaa tttttactca
      721 ttcatagaca cttccttaaa taacttttat tatagaaggt attgtaaata ataatattga
      781 caaaaagtga ctcaaaataa aaaaaacctt acattatact ggaatgaact gtattgatag
      841 tgtacctaaa agctctactg acataagatc gtgtaatcgg taaagtaatt ttattaatta
      901 tacgggatgt aatcaattag agaataaact aatcataaaa ggtactttta cattcataat
      961 tgtcgctttg agattctact ttggttcact atctgaccca attgcacatt ttcgatcatt
     1021 acaagtattg gtgtcgttag aacaactaaa taaaaactag cggtagattt ttcagaatct
     1081 atgctaattt ctgtatggat gttccagtga tggcaaattt ctcttttcat tgtttttctt
     1141 gtcgcatgat atgccttttt gtgttattca gttaaactat agaaattctt tcctagacag
     1201 atcttgatcc caaattttac gtttttgagc atcgatatag tttaaaatga cattactcat
     1261 atctaaagag tttagatttt ttaggactaa aactgtcagt tgttcttttt cttctttctg
     1321 ttaaagtatt gtcgcgactt ttcgtatacg ttaagatatg tcgtgaaaaa acaagttttg
     1381 tgacacaaaa aaacgaatga cttgaggaaa tcacctcaat cattcgttta aaatgctata
     1441 tattctttag tttaagatac ggaaattaat gccatcgacc acactagtag aatgaacgac
     1501 atttacttgg ccttttttta atttcgttat gtttagcata taaaaatatt atagagttta
     1561 cttacaatgc ttaaaacata tactgtataa tctgatcaat tttagccatg tcttgcaatg
     1621 gtaagttttc tatttttttg agttttcgtt ccttaaaatc aagagatttt aattgtgtaa
     1681 taattacttg tccttttata tctagctctt caggtaatga gtaacgtgtc ggtaaattct
     1741 ttatagtgga agtaattgga catatgaccg aaaacattgt tttacggtta aattcataac
     1801 gagagacgac tagtcctggt cgtctttttt gaatttcttt tcctacggag ggatcaaaat
     1861 caatccatac aatatcacct tttttaggaa tataaattct ttcttctgac actataaaat
     1921 ttctctccct tcaggagtta aatcttccca ttcgtctttc tcataatact cggcctcttc
     1981 cccaccacta aatggatctt caatttttgg aactaacgta attgttccat catcagaata
     2041 cacaacgata tattcttggt tttctgaagg tttctttccg ttatcagaag gtaaagttac
     2101 cactacagaa cttccttgta atctagattt tgtaacaagc attatcatca ctcccttaat
     2161 aaaagtatac tatataacac taagtaacgc aaaattcccc tttgtaaact atctagaaaa
     2221 ttgttttgtt taaagtatat cttattggat ataaatagaa ataaattgta gccagttcat
     2281 tttttcttta actaaaaaaa taatccaaga aacattgaac ctatggatcc aaaagctacc
     2341 caaatactat agctaacccc ccgctacctt caattttgca gataaaacgc tttgggagaa
     2401 aatttcaaag acaacaggcc atcctatcat gcccgattat aaacaaaaag ctggctattc
     2461 cttttgctct gacaaatttc aattgggaaa gttcacgaaa ctagcaggtg aagaagtttc
     2521 aactgttcgg atcaaagaat gcccgcttca aatagaaaca ttggttcaac gaatttcaac
     2581 tagacaagac tttgctattg tagaacgtga gatcgtagct atttttgtag aagaagggat
     2641 tttacatgat ccaactcata tcaatgtgga taaatggcaa cctcttatct ataaattcag
     2701 agaatataca actgccaacc agtcgttaac tttgaatttt agattccaag aattcaaaga
     2761 gtcataatga taaacatcgt taggtataaa taaaaaagac tcgcagcacg agtaaaaaac
     2821 aaatagaagc tatacattag aaaggtcgac tgtgacccta tagatgcagt atatgcagct
     2881 tatgagcatt tcttctgttc tctttgtttt tgggatctgt gctgaagtct ttttcgtttt
     2941 ttgccgctct ttctttgaaa aatcgattat gttatacctt ctccattact aattcaggca
     3001 tctgctgagt aatgattttt cgcgcaaaag aaatatctgt tacccaaggt tcgatttgtt
     3061 cttcagtcaa gacaagcggc attcggtcat ggattggtgc gactgtgcgg ttaggttcag
     3121 tagtcattat gattgattct gccatttttt catcctgatg gctacgataa aaaccgccaa
     3181 tatacactat tttttcctta tttgaaaaca taaatttgtc tttttcttca ttccactcat
     3241 tgggaaaaca caacgatttt gcaaaaatgg ttgatgaaag gtcttttttt cttctactgt
     3301 ctctgcacgg gcattaatca tcaattgtcc ttttttaaat ccggtaaatc cccacttcat
     3361 gatttccgga gtgaggatgt tttcttcctc ttttcttaac gtcacaacaa gatttgacgg
     3421 aaaaacttct ccagctgcta attctgctgc ctgcttcggt tgtttcgtct gggcttctcg
     3481 ataataattc tgaaggagct ctgactctag atcaaaaaaa taacgaccac acatcctaat
     3541 ccctcccaat ctttttttct atcatacact gcaacaagaa gttcgcacca acaaaacgct
     3601 ttcaattttt gtagaactaa aaaagttgtg acaagtgaca aactctccag tgaatggtat
     3661 tctcctgcca actcctcggt cacaagtcac aatattcaac aaacatgaga agctgctttt
     3721 tgaaattgtt ccttgtgact cggagtgaaa cggcaggctt acgacctctg ggtaaacggt
     3781 gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtag aaagctattt
     3841 tcacaaaatt tttcttaata ctcgaaacta agcgactttt tcacaacctc ttccttaaac
     3901 ggtgttcaaa agcttgcatc tgcggtaata agcccaacca aacgaaaaat atgagcagct
     3961 atttttattt ggctgttctt attacttgat gcagggcagc tttttcacaa cctctccact
     4021 aaacggtgtt caatcagcta accttcggta ttagctcaaa aaacggcaaa atatgaggaa
     4081 ctattttgcc gtttgtttct ctaatactca ggtcaaagcg ctgatttcac aacctctaat
     4141 acacggtgtt ccagaagtag cttcttcgaa aaataagccg aaatttcaca aaaatttgag
     4201 aagcaatttt cgtaaattcc ttcttatttc ttgaagctga ccacttctgt cacaacctct
     4261 aattattaaa gaaccttttg cgaagttaac aatctttctt tgatcaattg aaaattctgc
     4321 ctaagtagtg atagatcctg tgtgactttc aacaataaga tacttccctg gatttcagca
     4381 atcaacgctt tggcttgacg gtctgcttct tcatcggaca gtttttcttc agaaagtgcc
     4441 aggatatttt gtttcgtata cttgacccat tgattgacta attctagtag caacagacgg
     4501 tattcttcat ccactgtact caactcaata atcaaattac ctacaggaca gccatgataa
     4561 gtgatctgtg tctcatgatc agcgaaaatc cagtccaaca tttcttctaa tgcttcttct
     4621 ggctgttttc cagcatttaa gatgtcttcg aacaattctg tctgccatac gtccatatgc
     4681 gcatggatca ccgctagaca aacttctttt tttgaagaaa agtaataata aaattgacct
     4741 tttcctgtat cagaagctgc tagaatatct cggattgacg tttcatgata gcctttttta
     4801 taaataagat ctttggtcgc ttccaagatc ttttcctttg ttttcaatga tattctcctt
     4861 tttcatttct catagtccta tattatacag taaattcatc attttttctt cttaatcgtt
     4921 taaaaaagac tgtgccaaat tatctgacac agccctcact ataaaactgt tctcatatag
     4981 ctagatgttc attgattcaa gaactgcgag gacaaaagca attcctatct tatgatagtt
     5041 gctctaatac ttcctctgtt gtcatcactt gatctgcaat aaagccaaag ttcgtcaacg
     5101 ctgcatccat tgcttcttgg ccaggagcac caattgcatc tgtcgctacc acaacattga
     5161 atccactctc taccaattca cgcatatggg aatcgctaca caagtttccg ttcattccac
     5221 caagaattac tgtgtcgatt ccattttttc tcaattggag cgccaaatca ttgctttctg
     5281 gtccaaagat tttatgagga gagctgatga tcgtattttc atccaaataa ggtttcaatt
     5341 cttcgataaa atcggctcct gaaccttctt ccactgattc atattgactt tttctagcaa
     5401 acatctgctg ctcaagcatc atatgttctc ctgcaccgcc aaattgccat ttatggtcat
     5461 gtgggtaaaa ataatgagga gaaataaaga gtttgtatcc tttttctttt gcttgtttta
     5521 ccatttcaat catattttcg atcgtattgt atttttctaa gatatctttt gtcaaaccaa
     5581 agccaccgcc tgctggtttc aagaactcga cttgcgggtc agtgagaact actgctgtat
     5641 ttttattatt gaacatggtg gattctccat tcgttattta ttttaataca tcatttagag
     5701 cttcactcat tgtcggatga gaatagattt gatctctcaa taacgtataa ggaagttttc
     5761 cattcatagc tagcgaaatc aagttgatga cttcatgaga atcttccgca tagatacttg
     5821 cccctagaat caagtcagtt tcagggtcga ctaaaacttt gaatacacct ttaggatctt
     5881 ctaatacttg tgctttaggg acaccgcttg tcatatactt gaataatttg taattgacgc
     5941 cttgtgcttt ggcttgtttt tctgttaaac ctacattgga taaagtcgga gtgataaata
     6001 cactgtaagg cacagctttc cggttattcg ttgttcgttt attctcgccc ttcaactgat
     6061 ccataatgat tcgataatca tctagagaga tataagtgaa ctgcaatccg cctttgacgt
     6121 ctccaatcgc ccaaatgttg tctgcatctg tacgaaggta ttcatccaca gcgattgctc
     6181 cgcgatctgt tagtttaaca tctgtatttt ctaatccaag tgatgctgta cttggttttc
     6241 ttccagttgc agccaaaact tttgacgctt ggattgttac ttcttggcca tcttctgtaa
     6301 aggtgacggc agctgttgat tcttggtctg ctacttgatc tacagataca cctagatgga
     6361 attcgattcc cgcatttgtc atgtcttcta aaatcatttg cgcgatatct tcatcttcac
     6421 gtggaagaaa ttcagaatgg gcatcaagaa cgacaacttt agatccgtat tcattgaaca
     6481 ttgatgcaaa ttccaagcca atatatccag ccccgatgat cactaatttt tccggtaatt
     6541 gttcctgatc catcgcttgc gtagaatcaa tcaagtagcg acttgtattc aatcctttga
     6601 ttggtaaaat gattggttca gaaccagtat tgatgaaaat ccgttcgcct tcaacaatca
     6661 ctttttcacc attattcgtc acttcgattt gatggttaga aagaaaacgt gctgtaccgt
     6721 ccatcactgt cccagttgcc tcatcgctga tcatatgata atttttggcg cgaagcatgc
     6781 ccgtcaattt ttctttccga gcaacagcct ctgtaaagtc gattcctctt tctccattga
     6841 aaatcaatga tttagaagga atacagccga tgttgataca tgttccgcca tacatacgtg
     6901 ttgacttttc aacgactaaa accgattcac cttttgaagc taacgccttc gctaaagtct
     6961 taccgccctt tccaaaaccg atcacaatat tttgatattt ttccatcatt tttccctcgc
     7021 ttctttttta cctaccgatt ggtacaaaaa tatgataacc gataattgtc tattctccaa
     7081 atcatctgct ttatttgtca aaaaaaacca gacaaaaagc ggtcctttca cgtttttagt
     7141 ctggttcgat ttcctttatt cttctaaaca atcgttactt ctacatcgat atttcctcta
     7201 gttgctttgg agtaagggca gaattcatgc gcatcttctg caattttttg ggcttcttct
     7261 tcgctgatgc catcgatatg cacttctaat actacaccga tctgatagcc gccatcatct
     7321 aaattataaa gagagacacg tgcttttact gtggactctg ctgtcattcc tgcttctttg
     7381 atcatatgtt gtaccgcccc attgaaacaa gaagcataac ctgctgcaaa taattgttct
     7441 ggatttgttc cttctgcatg gattcctgga ggagtgattt tcatatgcat cgagccattt
     7501 ggtgcctcga cttctccatt gcgcccgcca tggttgatca ttgctgtttc gtatgctttt
     7561 ttcattgtac tgctcctttc gattgaccat ttgctacttg gctataatta tagtgtatga
     7621 caagtaaggc gctttctaca aaaattctgc ttattcgaat accagaatgc cgtcttctac
     7681 tatttttcca aaaaacaaaa aaatactact cgtgaacaac agcgtcatat ttgttccaaa
     7741 ataaatagca atcttttcta cataatcttt tatatgattg attttaagat acatatatac
     7801 cagaaagttg accccataaa ccaatactgt taaaaaaata accatattcg ttaccatttt
     7861 ttcctccttt tgctggtctc cctaccagca ctcgatttaa ccataccact ttttttgccg
     7921 tccaagcaac tagcctttca aaaagactgg tttattctgc tgttaatgat tcaagatcag
     7981 aaaaatgtcc gaataatttt gctaatttta ctaacgccaa cttgttcttt ccgaattcat
     8041 cattttctat ctgtaatact agtaacggct catgtaagct taaacggatc aaaaaccagc
     8101 cgtttccgta tggctcttct agatcatatc gaataccttc ttcattttcc gggtcgaagt
     8161 tcatcccttt ttcttcttcc aacagtcgct tcatttcttc taatatcttg tttccttgtt
     8221 cgcgtggttc atcgctgaac aattttaatc ggatttcttg tacttctacg ggctgtttca
     8281 actctttgat ttgttcatct aatgtgatac cttttctttt taattctggc aaaagcatca
     8341 ggatctttgc gatgacatat gcaccatcat ccagaaaata gttttccttg aatgcagcgt
     8401 gtccgcttgt ttcgatggct agctgtgtat ctttcccaag acggttaagt tctaatgctt
     8461 tattgattac atttcgatag ccggaaatat aacgaacttg gatgcctcct ttttcttcaa
     8521 tgaatctttg tagatgagaa gaagtagggg aattcgtcac gattcttgtt cctggatgct
     8581 cttttaatac gattgtactt aatactgcga tcaaattatt tcgattgatc actgttccag
     8641 aagcactgac aactgcagaa cgatccacat ctgtatcgaa aatgatccca agatctgctt
     8701 catttgctaa aacagcctgc ttgatacttt ccatcgcttc tttattatca ggatttggga
     8761 tatgattagg aaatcggcca tctggttcca aaaattggga acctgttgaa tccgcaccta
     8821 agctattcaa tactttttca gcaaagaatc caccagcacc atttccggca tcaacaatga
     8881 ttttccaacc atttagtggt ttgctttcta gtgttccaat ccccttttta atttttgtga
     8941 ctaaatcttg cgcataaggt gtcaaaaggt ctgctttttc tacgcttcca gtttgttcgc
     9001 tttttatttt ttgctgctgt gataggataa aagcaatatc ttctttttct gctcctcctt
     9061 ctgaggtaaa gaattttatt ccattataat aatagggaag atggctagca gtcagcataa
     9121 ccgcagcatc gcacgagaac tgttcaaatt gagtggacat aaacatagca ggcgtagtag
     9181 ctaattcgaa atcgatgaca tgtatccctt gttctttcag actttggatc aacgcctctt
     9241 tcagtgctgg tccgcttatc ctactgtcat gaccaatccc aatcgtccat tttttatttg
     9301 gatcggttga tttcttcttt ttctttatcc agtttgctag tccccagccg atctttttta
     9361 ccatgtctgt cgtcaagttt acttcatatc cttcaactgg taatgcgatt cctcgaatat
     9421 ccgatccatt ttgcagcgct ttcatatctt tcatataaaa gtcctcctca tttattccct
     9481 cattttttcc agcttttctg caaatcgctg tgcttcttct tctgagcggc aaataataat
     9541 gaatgtatct acaccggcca tcgttccgac aacttcaggg taagccactt catctagcca
     9601 attcgttacc acatcggcac catttcgttc agtcaatacg ataaccatga actgaacaga
     9661 ctggatacgc aaaacctcgc gtctaattgc tgtacgcaaa cgttcttcat ttaaagaaac
     9721 agatggctgg ttaaataatg tatagcgtac tattttgttt tcattttgac tttttactaa
     9781 cttcatttct cgaatgtctc gagaaatcgt tgcttgagtc acatcggcgc ctgcttcatg
     9841 cagccgcgca agcagctctt cctgtgtccc aataggttgt tctgtaatga tctggcggat
     9901 cagtgcttgt cgctgtttct ttttcatatt agacacctct caatgttgat tatagcaaaa
     9961 gataagtaat atttcttcat attttggtat tttttacttt tattttttgt tttcattcag
    10021 gttgctaacc tttttctatt ttaacacgca aaatcgtctt cattttttca ggtgctgatt
    10081 ttcttggatc gctgatgtaa atctctttgt gttctttaga agctctttca tagccttctt
    10141 ttgcgatgaa tgcttctaat ttctcaaacg ttgctggttc ttcggcatag ggcccgacgt
    10201 gtaagatttg ggcacaaaga ccttcttcca tctttttgaa tactacttgt tctttcaagt
    10261 cttccggaag tttgctagaa cgctgaatgg cttcttgtgc tatcgcttct gtaacaaagt
    10321 caggctgtcg gatcatcaat tgataagaaa aatgttcttt tttcatcact ggttcatgca
    10381 aatacttttc ttgcagtccc cattgtcctt ccagtggata gacagtatac atctgataat
    10441 caggaatcag ccaatttttt ttaggcgaca tgcgtattgc atagctgact gcatatagac
    10501 aggctactct tcgtttaaag tcttcctgat tcgggtcgcc gatccctctg atgctaaaga
    10561 atgatttttt aggaacctct agtatttgcg ggcttttttt catactatag ctcttgtctt
    10621 tacgccattc aattttttcc atttttcttc ctccgcgaaa ttccatttag ttatttatta
    10681 tcatacctct ttttgagtga cttggctaat cgtgttgaca ctatttttca gtttgtgcta
    10741 gaataagtga agtaaataaa tcgtacagat aacacgtttc ggcgtgtcga gagagaggcg
    10801 gtttctattt ttataataga aatcactctc tttttttacg aaatttttta gaggtgatgt
    10861 aaatgacaaa acaaaaacag ctgcttttag tacctgcagt aattgcaaca gggatgatgt
    10921 cttttgcggg cgtattgatc gagacggcca tgaatgtaac tttcccaact cttatcagac
    10981 agtttgattt aacgactgca caagtccaat gggtaacaac gatttatctt ttgatgattt
    11041 cgatcattgt tccgctgtct acttatttga atcgcaattt tagtctcaaa aaactctttt
    11101 tagcttcaaa tctgcttttc ttggcaggta taatgatcga tttcttctct cctaccttca
    11161 tggtcctatt gtttggtcga ttgctccaag gtgcagcgac aggtatcgct cttccgttga
    11221 tgttccatat tatcttgaca tttgcccccc tcaatcgacg aggcgcgatg atgggtgtcg
    11281 gtactttgac aacggccatt gctccagcaa ttggccccac ttatggaggc attatgactt
    11341 cacattttac atggaatcat atcttcctgt ttcttgtgcc cgttttgttt ctttctttga
    11401 ttatcggctg gtttgctatt cccgagatgg cagtacaaaa aagtggttat ttggattgga
    11461 taagcgtttt aggaatttgt cttttgttta gtggaagtct aacatttttg agtacgttgg
    11521 gaacagtttc cagctggatt gctttaatca tcggcggtat tggctggttc cttttttact
    11581 atcgaagtaa aaaagtggag catccactga tccgactgtc tattctttca aataaaacat
    11641 tccgcttgtt tttgattggc ttcttagttt atcagttttt attacttggt gtatcttttg
    11701 tcttgccgaa tttccttcag atcgttcaag gaagtagtcc ttttgtcgct ggattagcga
    11761 tgcttcccgg cgcagcggtt ggtgctttgc tttctccttt ttccgggaaa atgctggatc
    11821 aatatggtcc gaagaagcca atttttgctg ggctgattct ttctttgatt ggttggctag
    11881 cattattcct actcatagga cacgcttcag tgggtgtatt gattgcttgt catgtgtttt
    11941 atatgatcgg tatcggatta tcttacagca atatgatgac caccggaatg aatgcactga
    12001 atgaagaact acaaggagac gggaacgcaa tgttcaatac cttgcagcag ttttctggcg
    12061 ctgtggctac ttcattagta gcggtcatta tcaattacgt ccagcatcat acttcccata
    12121 actatgaagt gtctactaca ttaggatcaa aagcagcatt aggcgtcttg ttgctgttgc
    12181 ttctcgtaag ctttgctcga ttcgcctatt atctgttctt tgctaaaaaa gcgtagattc
    12241 catatacggc aggtgttgca tctgccgttt ttttgtgtga aaatggttgt ttgtaaaagg
    12301 aggctttttt atggaaaaaa ttgccattat cggtggcggg atcattggta tgaccctagc
    12361 cagttactta gatacatcaa aattcaatgt tgctttattt gatgaaggga caggacaggc
    12421 aactaaagct agcgctggga ttatctcccc ttggttgtcg aaacgcagaa acaaacaatg
    12481 gtatcgtctg gctaaagacg gcgctgcttt tttccctaaa cttataaaag atttccaact
    12541 tgatcaaacg atttacgcac aatcagggac acttttgctt cgacctgaaa aagatttagc
    12601 tgaattggct gttcttgccg agaaacgaaa agaagaagcg ccagaaattg gaaacatcga
    12661 atggctttca cctgaacaga catctcaagc acttccgtta ttgaaaccag cagtttcact
    12721 gcgtatcagt ggtggtggtc gtctggatgg aaaagcatat ttagaacatc ttggtcagcg
    12781 tttagcacaa aaacaaatgg agcagatcca ggcaaaagtc actttgcata agaagagcga
    12841 ttcttggctc atcaagggac cgtttggaga atacacagct gatcgtgtaa ttttgacacc
    12901 tggcccggca cttaagcctt tattacaaga attaggctat gctgcagata tacgtccgca
    12961 aaaagggcag ctcttagcat ttcagacatc ttataagatg agtcaagact ggcctgttgc
    13021 tatgcttgac ggagaagctg atttcattcc tttcatggat ggaaagatcc ttttaggtgc
    13081 tacccatgaa aacgatcaag gctgggattt ggctcctact agcgaagctt ataagggatt
    13141 gactaagagt acagaacagt tcttgactga tccagatcag ataaaaaact ggccatacga
    13201 gttccgtgta ggtacccgtg cttatacgtc agatttttcc ccatttttcg gcgtactgcc
    13261 agatgatcca agcttactgg ctgctagcgg tctaggctct tctggcttga ccacaggtcc
    13321 ttatatcggc tatctattag ccaacttctt aaatactggt cattggccta cggaagatta
    13381 tcaaaaggac atctccacct atattacgaa aaatccatca tagaaaaaca gctttttcaa
    13441 gtaaggatcc cgagcgatat tgcgcatgga ttacttcttg aaaaagctgt tattttagtt
    13501 caatttctga atcaaattct ccaaactttc ttttgcttca tctggcaaga gatcttttcc
    13561 tatctgagct tcaatgaatc gtaaacgaat atcaagtcgt tgtttcacca gatttttata
    13621 ggacgtatcc tcaaaagaaa caggaaaatc tggtataggt aaatagtgga tgtcttcaaa
    13681 tggaccaaac gacttgaatt ctgccgtttg ttgcacgatt ctttcaacga ttgacaatgt
    13741 cgtttcaggt ttgatttttt tatcatcgaa atatccagta ttcaggacat agcaggctgt
    13801 ttgctgtttc aaaaacaact ctcgaaaagc ttgatagtct tccctaagag gatagacacg
    13861 gaaaggatta gcaaatggtt caatgactag ctcatctagc tgtctttttg tagtgatatt
    13921 ttccgcgtct gatcgttttg ttgctaatgt tgcaccaaaa gacgctgcta aaactgggtc
    13981 attgatcttg ataattggcg gaagcgaatc atctttcatg atccaaaaaa cagcatcgat
    14041 cttttcgcta agatgatcga ctcggtcggg tgtcgcataa cgtgatttga ctgtccgccc
    14101 atttccgttt cgtatatctc ctgttactag gactttttct cctttacttg tacatgtcac
    14161 gcccacattc tgacaagtaa ggaaagaaga aatggccgga tcatcagacg gatagtcttg
    14221 tgttttatca aagtaagaag gttccaaggc agtagcaaaa ccattttttc gagaaataac
    14281 gaaagcatcg tcatgcaaga tcgaaacaga gtgaccttcc gtatgttttg ctaaggtaat
    14341 cgttgatttt ccagaaccgg acaacccaaa tacagccatc gtataggtct ggtcattact
    14401 agcatattgt ttcatcccac cgtggcaggc aataaagcca ttgcgatttc ccaatgccca
    14461 agcaagcgtc aaagtcgctt tttttaattc tccaaagtaa cgtaatccta gcacagccgc
    14521 tgtattatgg agagcatcaa acaaaatgag tccatttgga aatgtttcat gtgtccattc
    14581 gggatcacaa aagatataaa gatctccctc atcaaaggaa acagactttt gataagtctc
    14641 taagatcttc gaattcgctg gctgaaaatt cagcaaataa gaatacaaat tgttctcaaa
    14701 tccttctgga atcagcaaat gactttgcac agaaaattct tcagataggc caacgattac
    14761 ttttgtatgg taaaactggc gcttgcgact ttgatacaca gcttctctta aaattttctc
    14821 gtatttgctt tgttccttgt ctaagtcctc aaagatccgc cgagcacttg ctgttcttcc
    14881 cacaatgctt ccatcattga atactagtgt cctaacatca gctggtaaat ctagttcttc
    14941 agcatgtgag attgttaaat ctgtgatgat cgttcctgga ctcccttttg ctagttgata
    15001 agctgtcttc ctatcaaaaa cttcatgaac attattaccg taaaatgtcg tttctacaat
    15061 cgatcgaata ctggataaca gtggatttcc acttgtgatt tcgtttaatt cgagactctc
    15121 ttttgtactc atggctcctc ctcattccct aaacaaaaaa acgttttctt tattatacat
    15181 tattcgagtt tttatttgta ctgctgcgct gtgggaagca aacgagttat ttttcacaca
    15241 aaaaaaccga gaacttgaat aaacaagttt ctcggtttca tcattttcct tttatcggct
    15301 tagtaccagc cgtttgctaa ccagaatgtt ttagcagcat cccatgaacc ataacgagat
    15361 gttacatatt gttctgctac acgttcttga ttggcagctg aatagtcgcc gtttaagtat
    15421 gaagcatcta attgataacg gccgatgtaa cgtccgttag tagctgtgta tgaaccgcct
    15481 gattcttttt gtgcgatcca ttcttttgca gagcttgaag ttggcgctgt tgcagcagct
    15541 ggggcagcag gagctacttc aactgtttca acaggtgcaa cgtatgtatg ttcttgcgtt
    15601 gctgtttcag ttgtagatgc tgtattttct gttgttttgt tttctgttgt tgctgaagaa
    15661 tcatttgaag ttgggattgt taattgttca ccaacataaa tgcggttgat gtttgcgatc
    15721 gaattttttt cagcaattgc atcgatcatt gagttgtctc ctgcaaattt ttgtgagatc
    15781 ttagataatg aatcacctga ttttactgta taaacttcat cagcgtgagc atttgtagtt
    15841 cctacaaaca ttgcagtagc accagcagca aaagttgtac ctaaaacaat tttcttaaat
    15901 gaattcatat taaactcctt tttttctccg ttttttattc tttcgacgct attaacttta
    15961 tcatttagaa atatttcata ggtaaaagaa acatgacatt taatgacaaa ataacgaatt
    16021 atttaatatt tgtaacattt aaacaaatat ttttttgata caaaaccata aaagccttgt
    16081 tgtataagca aagtaatcgt ttttctatgt ttttttattt ttgaatgaaa aa
//
LOCUS       DAZAOD010000058        15830 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000058 DAZAOD010000000
VERSION     DAZAOD010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.059"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            60..383
                     /locus_tag="ACHDPO_001863"
     CDS             60..383
                     /locus_tag="ACHDPO_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFN3369479.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            565..1935
                     /locus_tag="ACHDPO_001864"
     CDS             565..1935
                     /locus_tag="ACHDPO_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFN3369480.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(2065..3366)
                     /locus_tag="ACHDPO_001865"
     CDS             complement(2065..3366)
                     /locus_tag="ACHDPO_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFN3369481.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(3720..5711)
                     /locus_tag="ACHDPO_001866"
     CDS             complement(3720..5711)
                     /locus_tag="ACHDPO_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFN3369482.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(5855..6121)
                     /locus_tag="ACHDPO_001867"
     CDS             complement(5855..6121)
                     /locus_tag="ACHDPO_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFN3369483.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(6631..8757)
                     /gene="pnp"
                     /locus_tag="ACHDPO_001868"
     CDS             complement(6631..8757)
                     /gene="pnp"
                     /locus_tag="ACHDPO_001868"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFN3369484.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(8945..9214)
                     /gene="rpsO"
                     /locus_tag="ACHDPO_001869"
     CDS             complement(8945..9214)
                     /gene="rpsO"
                     /locus_tag="ACHDPO_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFN3369485.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            9465..10028
                     /gene="def"
                     /locus_tag="ACHDPO_001870"
     CDS             9465..10028
                     /gene="def"
                     /locus_tag="ACHDPO_001870"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFN3369486.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(10281..10802)
                     /locus_tag="ACHDPO_001871"
     CDS             complement(10281..10802)
                     /locus_tag="ACHDPO_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFN3369487.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(10805..11647)
                     /locus_tag="ACHDPO_001872"
     CDS             complement(10805..11647)
                     /locus_tag="ACHDPO_001872"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFN3369488.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(11640..12365)
                     /locus_tag="ACHDPO_001873"
     CDS             complement(11640..12365)
                     /locus_tag="ACHDPO_001873"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFN3369489.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            12541..12837
                     /locus_tag="ACHDPO_001874"
     CDS             12541..12837
                     /locus_tag="ACHDPO_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369490.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      13093..13267
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            13405..14997
                     /locus_tag="ACHDPO_001875"
     CDS             13405..14997
                     /locus_tag="ACHDPO_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFN3369491.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            15010..15750
                     /locus_tag="ACHDPO_001876"
     CDS             15010..15750
                     /locus_tag="ACHDPO_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFN3369492.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         4530 a         3253 c         3050 g         4997 t
ORIGIN      
        1 tttatcctag gattaattat aaaaataaaa cattcgttga ttcgaaggag gttaaacaga
       61 tgtttgaaag ttttgatagc agccgcaacc gttacgcttc agttggtgtc gtatcaagtt
      121 tgccagatga attgattgac agtatatggt ttattattga cctagatctt aagggagtca
      181 ttccattaga aaatatatta acctttgatt tgatcgaaaa tcgtggaaaa gtgacgatgc
      241 atttttctca agcaggaagc aatgtggaaa tggatattga tttgccgttt gcctattcga
      301 accaatttcc tgctcaagta tacgcctatg atgacggtac gagagaaacg atccttttac
      361 caagtgagat tagacaatat taaggtgata gataaacgtg gatgtccctt attttacaga
      421 ccaggccaag ttgttgattc tttgactcaa ttcttggctt ctttttatgg agtttcataa
      481 attatcattg atttctaatt ggtattctca ggataaacgc tatatactac taactaaatt
      541 ttaaagatat aaggagttta aaagatgcgc gatttaacaa aaggaagccc cgctaaactg
      601 attttgatgt tcactgttcc tttactgatc ggaaatgttt ttcagcagtt ctacaatatg
      661 atcgatatga tcatcgtggg tcagacgcta ggtaaaaatg cgctggcagc ggttggtgca
      721 actggaagcc tgacattttt gatcattggc tttgcccaag gtttaacagc tggtttagcc
      781 attattaccg cacaacgtta cggtgcaaaa gattatcggg gtctgaagaa aagttttgct
      841 gctagtgttg tcattagtct tgtcgtcact gtgattttaa ctgtcctaag tctcctgttt
      901 attcgtccga tgcttcaatt gatgcaaact cctcctgaaa tacttgatca agcacaaaca
      961 tttatttcaa ttattttatt agggatcttt gcatcagtca gtttcaattt gctttctaat
     1021 gtcattcgcg cacttggtga cagccgcaca ccactattct ttctgatcat tgcggtcatc
     1081 atcaacgtcg tacttgattt gatctttatt atctattttg gcatgggtgt ggaaggtgca
     1141 gctattgcta cagtaatcgc acaagtttct tccagcgtac tgtgtctagt gtatatcaag
     1201 aaaaaaatgc ctttgttaca gttacgcaaa aaagatttca aatttgaaaa agaagagttt
     1261 gctgtacacc taaatgctgc tttgccaatg gcgtttcaat cttcgatcat cgctgttggt
     1321 gctatcgtgt tacaagcagc actaaatagt ctagggacag atgtcgtagc tgctcaagcc
     1381 gctgctggtc gtatcgacca atttgcaaat cagccgatga tgtcatttgg tattgcaatg
     1441 gcaactttca ctgcacaaaa ctatggtgcg aaagaatatg gccgaatctt gcaaggggta
     1501 cgtcaaactt tactgatgag tgtcggattt agtctcttag caggtgctat cgtcattttc
     1561 ttcggtcatt tctttgttca attgtttgtt agcccatcag aaacacgtgt atttgaatta
     1621 gcacaaacct acttcaatat caatgggtct ctttactgga tcttagcagt cctgttcatt
     1681 ttacgctaca cacttcaagg gcttggacaa agcaagatcc ctacgatcgc cggtatgatg
     1741 gaattgctta tgcgttcttt tgcagctatc gttcttacag gaatgtgggg atacccagga
     1801 gcagcagcag cttctccttt agcttggatc ggttctgttg ccgtgttgct ttactcttat
     1861 atgcgttcga tgaaacaatt gaaacacatg ggtgaagagg aacatttcac attagaacat
     1921 gcagaagcaa gatagccttg attaaaagaa atcgttgcgg ctaaaaatga aaacttttat
     1981 tgaaaatatc ttcttcgttt accgaaaaca ggttttttag ataacaaaaa ggctgtgaca
     2041 aaaaatgtca cagccttttt tcttttattc tgtttttctt tccgtggact ctactttgaa
     2101 ataatcgata tgtgcatgct ggtattctaa taccgtgaaa cggaatgatg caatctcaat
     2161 gattgttcct gcttttattt ctttatatcg gctagaagca aagcccgcaa gtgtagtaaa
     2221 attcgtttct tcaaactctg gaatctctac atgaaaataa cgctggaaat catctaatgt
     2281 tagtttgccg gagatgatat aagagccatc tgactgttcc gctatcaatg cttcgtccaa
     2341 atctgtctca tctcggattt ccccgacgat ttcttctaaa atatcttcaa tcgtcactaa
     2401 gccgcttgtc cctccgtatt catcttttaa gatagcaata tgcttaccct tttttcgcat
     2461 gatcgtcaat aattttttta tagggatcgt ttcagttgtt acgatcggct cttcaatcaa
     2521 ctgttctact gtcagctggt catctttata agattgcttg atcaaatctg gcaaggtgac
     2581 ataacctaaa acattgtctt ttgattctaa gataaccgga tagcgagtat gtccttgttc
     2641 aatcgaagct tttatcgctt ctttgacggt ttctgaagct tcgaatactt gcatggacgt
     2701 acggtctact tgtatatctt ttgccaaggt atcatcaaat tcaaacacgt tttccaaata
     2761 ataatattct tctttggtca actctccttt ttcataagaa ttcaatgcga ctaatgtcag
     2821 ctcttcttga gacaatgtct cttctccttc agatacgaga cgcacaccta atagcttccc
     2881 tagccctgca gctgaatgat tcaataccca aataaaagga aacattactt tataaaaata
     2941 atgaagtggt ttaactacga acaagacgac cttctccgta ttgacgatac tatagctctt
     3001 aggaagcagt tcgccaataa ccacatcgat atacgtaact aaaataaatc ccagcgccac
     3061 agagattgta ctgctaatag ccgaactaaa aggtagttta ccgatcactg gttctagtaa
     3121 agccgcgaca gatccttcac cgacccaccc gatgatcaaa ccggttagcg taattcctaa
     3181 ttgactagct gataaatagt tatctaaatg gtgtgtaaca tgaagagcta gcttggcgtt
     3241 ctttacattt tccttttcta gttgttccaa tcttgatcgt ctgattttca ctaaagcaaa
     3301 ttcacttgct acaaaaaatg aagtaattgc aatcatcaaa aataaaataa tgaaattgat
     3361 aaccatattc tcccgccttt ctctttttct attgtaccct ttttctacaa aaagattgaa
     3421 aataatgcgt attcatattt aggaataaaa aaggagatgc ggcatttttc agccacatct
     3481 ccttatcact tcaaaatcat tgcgttactt gttgctaaac agctttttca tgacctctga
     3541 taaaaacggt attcaaaagc ttgcatctac ggcattaagc ccaaacagat gaaaaacatg
     3601 agaagctgtt tttatctgct cgttcttact gcttgttgca gtacagcttt ttcatgacct
     3661 ctgataaacg gtgttcaagt agctgacatt cgacattagt tcaggtcaaa gcgctacttt
     3721 cacaaccgct ctttcaacca tgttttccga gtatttccaa tgataagcgg aacagtttca
     3781 tgttttactt cgctgtactc tagcccaaac catgtttctg gcgaggtagc gatttttttg
     3841 attgccagtt ttgcctgcat gatttgacgt tgccattttc ctagagttgt cacattggaa
     3901 actacttcat caatcaggac aaattggaaa tcgccaactt ctcgccctgg tgtcagagag
     3961 tatctttgtg gctgttttgg caaacggcct tgtttcatca aatcatggat gacttggcga
     4021 acatatacgt tgatttcctg ttggaccctg aaacctaaga acagattcac ttggacaata
     4081 aaatcagtgt ccatcatatc tacttgatat tctttcgtat atggctcatc cgtcacttcc
     4141 acatgaacaa accaatagac tcgtgctctt ttaggccgtt tatctaaaat cgaatagatg
     4201 aactgtcggc caactttatc ttcagccata tcaggaacca agaagaccac atttgtctga
     4261 tagattggta aagaagtatc atcacgtaat tctctaagct gcgggatata atctctcaaa
     4321 gacacatcct cggttgacga ttcgcgaata atgttccctt gttcccaaat aaacatcacg
     4381 actaagatga tcaaaccaat cagaacggct acaaaaccgc ctcggaagaa tttgacaaca
     4441 cttgagataa agaaaacgac ttctatcgca ccgaagaaaa aggtaactaa atatgcaagc
     4501 caacgagaat gcccattttg gataagataa aagtaaagca gtgctgttgt catcaacatc
     4561 gtcacagtga tcgatagacc gtaagcagct tccatatgat gagacgttcg gaatgtgaca
     4621 accactagag aacaggcgat ccataaaatc agattgactg ctgggatata catttgcccg
     4681 atactgttcc caggatacat gatctttaac cgaggcagca gtttcaactt gattgcttct
     4741 gaaactagcg taaacgaacc tgtaatcaat gcttgcgaag caatgactgc agcgactgtt
     4801 gcaaaagcaa cgccgatcac gatccaactt tgaggcatca tttggaagaa tggattcagg
     4861 ttcttgattt gctgtgcttc agggttttga taaacattca acaaccacgc agcctgccca
     4921 aaataattga taaccaaaca aattttgacg taaggccagc tcagacgaat atttcgtttg
     4981 ccgacatgtc caagatcgga ataaagcgcc tctgcacctg tcgtagccag gaaaatattt
     5041 ccaagaatga acaagcctaa tttgttatct gcactaaaaa gcagctggat agcataataa
     5101 ggattcagtg cacggataac tgtccagtct tgactgaagt tcattaatcc cattacgcct
     5161 aaaaaagtaa accaagcgaa catgattggt ccgaatgctt ttccgacaat atctgtacca
     5221 aagcgttgga ccatgaataa aacaaaaata ataactaaag tgataatgac gatcacgttc
     5281 tggttattac cgaaccggtc aaaaaactgc ggaattcctc gcaagccttc aatcgcagtc
     5341 gttaccgtca cagcaggggt caatacccca tctgctagta aggcagctcc tccgatcatt
     5401 gcaggaatga tcaaatattt cccacctttt cggacaagtg tgtagagtga gaaaattcca
     5461 ccttcaccat ggttatctgc attcaatgca atcacgacat atttgattgt tgtcagtaga
     5521 gtcaatgtcc aaaaaatcaa tgagactgat ccgataacaa aatcaggatt gattcctgac
     5581 aatccgccat tatcttcaac aatcgatttc ataacgtaaa gcggacttgt cccgatgtct
     5641 ccgtagacga ctcccatcgc tacaagcagg ccagccattg atatcttttt ggtattgtgc
     5701 gttgttgcca cgtttttccc tcatttcttg ttatatggat atcctttagg taagcttgaa
     5761 tgatagatga tattcttatc catgacaccc gctttcctaa attgcttcta attatccaag
     5821 taacacactg aagtgtcaac ttatttgaat aaaattattc tttctttgga cgttctctga
     5881 tacgtcttgc cacaaatgaa taaagagcaa ggcaaaaaat tgcacccaat aatgctggta
     5941 tcaaataaaa accgccgagt tccggtccca gtggtcctag taaaaattcg ccgagccaac
     6001 tacctaaaaa accgataatg atatttccag atacgcctcc cgggacttcc tttcctaaaa
     6061 ttgcgccagc tatcaaacct aatataccgc cgataaataa cgaccataaa aaattcagca
     6121 tctcctttcc ctcctttatc catatttctc acttttattt tacgctttat tcagaaggac
     6181 tccaaaaata tgcgccaaga aactccagaa aaaaagaagt tgtaacaaaa gtgttcagct
     6241 tatttccgta gaagctgctt ctggaacacc gtgaatcaga ggttgtgaaa tcagcggttt
     6301 gacctgagta ttagagaaac aaacggaaaa atagttcctc atattttgcc gttttttgag
     6361 ctaatatcga gggacagctg attgaacatc gtttattgga gaggttgtaa aaaagctgtt
     6421 ctgcatcaag taataagaac agccaagtaa aaacagctcc taatgttttt aacttggctg
     6481 gacttattac cgcagatgca agcttttgaa caccgtttat tcgaaaaaaa aggactgtga
     6541 cacggctttt gtcacagtcc ccttttttcg aataattatt gtccccctgt caccttcacg
     6601 atcacaagta cattattcct atgaattaaa ttatttttct tcatttttcg ttgaaccatc
     6661 ttcgttcaac attgcttttc ttgacagatt tacgcgtcct tgtttatcga tttcagttac
     6721 tttcacaagg atctcatcac ctagtttaac aacatcttcg actttattga cacgatcgtt
     6781 tgctaattgg gaaatatgga caagtccatc ttttcctttg atcaagttga cgaatgcacc
     6841 gaatttttcg atacggacaa ctttccctag ataaacttca ccaactttga cttctttggt
     6901 caaatcttcg atgatcttga tagctttttt gatcatttct gcatcagctg aagcaatact
     6961 tacttttcca tcttgatcga tatcgatttt cacaccagtt tcatcgatga ttccgttgat
     7021 cgtatcgccg cctttaccga taacatcttt gattttagca ggttcgatct ggatcatttc
     7081 gatttttggt gcatattggc ttaattcttc acgtggagca gcaatcgttg aagtcaattc
     7141 ttctaagatt tccatacgtg cttgttttgc ttgagttaat gcttcagtta ggatttgttc
     7201 tgtgattcct tgaatcttga tatccatctg taaagcagtg ataccatctt ttgtaccggc
     7261 aactttaaag tccatatcgc caagatgatc ttccagccct tggatatcag ttaggatcgt
     7321 atagttttca ccatcagaaa caagtcccat cgcaataccg gcgactggcg ctttgattgg
     7381 tacacctgca tccatcaatg ctaatgtgcc agcacagata cttgcttggg aagaagaacc
     7441 atttgattcc aatacttctg ctactaaacg gatcgtataa ggaaattctt cttctgaagg
     7501 gattacttgt gctaacgcac gttcacctaa tgcgccatgt ccgatttccc gacgccctgg
     7561 agagcctgca cgtcctgtag aaccaacaga aaattgaggg aaattgtagt ggtggatgaa
     7621 tcgtttgctg acttccaccc ctaaaccatc aatgatttgg tgctctccta gaggtgcgag
     7681 tgtacaagct gataaagctt gtgtttgtcc tcgtgtgaac aaacctgatc catgtacacg
     7741 tggcaataag ctgacctctg atgacaatgg acggatttca tccaatttac gcccgtcagg
     7801 acggatctta tcgatggtga tcaattcacg tacgacatct ttttcaagat cttctgtgat
     7861 ttgtttaact tctttcaaca agtgatcttc atcttcatga cctgcaaatt tctcagcata
     7921 agcttcgcgg atatcgatct tcacctgctc gatattatct tcgcgagcaa gtttttcttc
     7981 agtcattact gctgctttca ttgtagcgta agaagcatca aagatttctt ttttcaatac
     8041 ttcatcaact tgcagtaaag tcacttccat tttttctttc cctactgctt gaacgatttc
     8101 ttcttggaaa gcaactaact ctttgatagc gtcaaaacca aacagcaatg caccaagcat
     8161 gtcttcttct gaaacttctt tcgcgccgct ttcaaccata ttgatggctt gtttcgttcc
     8221 ggcaacagtc aattcgatat ctgtttgttc tgcttgttct actgttggat tcaagacgta
     8281 ctcgccattt acacgaccaa cttctacgcc tgcgattggg ccgtcaaatg ggatatctga
     8341 gattgatagt gctaaagaag aacctagcat tgctgccata gctggcgagc agtctgtttc
     8401 tacactcatc acgatgttcg ttacttggac ttcattacgg aagccttctg caaacatcgg
     8461 gcgaattgga cggtcgatca aacgggcagt caatgttgct tccgtacttg gacggccttc
     8521 tcgtttgatg aaacctccag ggattttccc tgctgcatac attttttctt cataattgat
     8581 cgttaatggg aaaaagtctg tatcttttgc ttctttagag gccacagctg cacttaagac
     8641 tactgtatct ccataacgga ctaaaacggc tccgtttgct tgttttgcta gctgaccgac
     8701 ttcgatttgt aagggacggc cgccccatgt cgttttgaat acttgttttt ctgacataac
     8761 ttctcctttt ccttctcgtg aaagcaagac gctactaaac aaatgaaaac tgccgaaagc
     8821 cgtcttttga gcagctttca tttggttagt aggagtccat ctagcttgat cacggaattt
     8881 tacttaattg atatacgagt aaaaaaagtg agattcatgt gaatcccact ctttttgact
     8941 aaaattaacg acgcaagcct aaacgtttga tcaattcgcg gtaacgttga acgtcagttt
     9001 tacgtaagta agctaacaag ttacggcggt gaccaacttt tttcattagg ccgcggtatg
     9061 aatgatggtc ttttttgtgc acgcgtgcat gttcattcaa gtggttgatt tcttcagtta
     9121 atacagcgat ttgtacttct ggagaaccag tatccccttc atggcgagcg tattcgttga
     9181 tgatttcatt cttgcgttct tttgaaattg ccatttcttt cacctctttc gattattccc
     9241 ctgcgactga gtaaaacgtt ggtgattcgc ttaaccaagt ggcaggtcat gtgcctagag
     9301 cacacagcta tactttacct gaaaccgggt tgaaaatcaa gtagttaatc attaagaaaa
     9361 ggtagttttc aaacaatctt actactactt ttccattttt gtggtaaact ataatgcgaa
     9421 aatagacttg aaacacagtc ttttaagaaa ggggtacata ttccatgatt acaatggatg
     9481 atatcattcg tgaaggaaat ccgaccttac gcgaagttgc aaaagaagtt tctcttccat
     9541 taagcgaaga agatatctct ttaggaaaag agatgcttga gttcttaaaa aacagccaag
     9601 atccaatcaa agctgaagaa ctacacttac gaggcggtgt tggcttagct gctcctcaat
     9661 tagatatttc taaaagaatc attgctgttc acgtaccaag tcctgaccca gaggcagatg
     9721 gaccttctct aagtactgtt atgtataatc ctaaaatttt gagccattct gttcaagatg
     9781 cttgtttagg ggaaggtgaa ggctgtttat ctgttgatcg agaagtacca ggatatgttg
     9841 ttcgccatgc caaaatcact gtgtcttatt atgatatgaa tggtgaaaaa cacaagattc
     9901 gtttgaagaa ttatgaatcg atcgtcgttc aacatgagat cgaccatatc aacggtgtga
     9961 tgttctatga ccacatcaac gatcaaaatc catttgcact aaaagaaggc gtattggtga
    10021 tcgagtagag aattggcagg ttccttcgat actatgctac aagaaagctt tataaaaaag
    10081 gggagtgctc aaaagctgca cttccctttt ttatgtttct ccactaatcg aaatttagat
    10141 agacatctag aaatcgcaat tccaaaaaat tctgtgtatt ggatacgcat cttttcttat
    10201 tttttcttat ttcttccata tgggtgttta tctcagagat gatagaatag tttctaggat
    10261 aaaaagtagc agctacgatg ttatccttcg tagaggattc ctgcttcagc tagtttttgt
    10321 ttgatgtttt tcagcatatg cttttctggg tagcggatcg tatgcagatg gatgccgcct
    10381 gttaattcgg ataacaaagt agcattactt ttttgataac gtctcataaa ggaatcgata
    10441 tcttgtggcg ttttgatgtg caaagttcct gctaactcac cgtaaagggg atgttccaca
    10501 attacatcaa tgatttcacc accattttca acgattagtc tcagttcttc ttctgtttga
    10561 tcttttccat gctggacagc gattttactg atgtgcccag tattggtttc ttctgtttcg
    10621 aggatataac ctcttgctgt tgccacgata cttttacctg cagctcgtag taaagcaata
    10681 tcgcctacaa tgatctgacg gctgactcca aaagttttcg caaacttgct agcactcact
    10741 ggtttttctg tatttgccaa ggtttgcatg atttgttttc gccgtgtctc tccttcgatc
    10801 acacttattc ctccttcatt ttgttttggt attcgcgcga gtgtttcatc aaatcaacat
    10861 acgtgtctgt tattgtttcc ttatatccct tatttttcag cagactaaca actttatcca
    10921 atacttgctg ctctcttttt gcatcataaa ctgcttggtt ttcttctttt ttcacttgtc
    10981 ctattttagt taccgtatcc attctttttt ctaataaagc aaccaactct cgatcgatca
    11041 tatcgatctt atgacgtaat gtttcaagag actcttctgt tagttcttcc tctactgtct
    11101 tgatgatacg agcaggattt cctgcaatca ctacattgtc gggaaaagat ttggtcacaa
    11161 ccgaacctgc gccgactact acgttgtccc ctagagtgac acccggcgtg acgataactc
    11221 ctccgcctaa ccaaacatta ttaccgattt taatgggttt tgcgtactcc agaccgctgt
    11281 tacgtttcac tggatgtagt ggatgcgtcg ccgtgtaaag ctggacattc ggagcgaaca
    11341 tgcagttatc accgatttca atcgtgctga catctaaaaa tgtacaattg aaatttgcat
    11401 aaaaattctc cccaacaaat atattatatc cgtaatcaaa attgataact ggctccatat
    11461 agattttttt ccctgtacgg ccaaaagtct ctttcaacaa ttgggatcgc agttccgctg
    11521 attctgcttg gttgatgatt tggctttgac ttcttgcaaa catacggtcg gcaaccagct
    11581 caggatcatt ggcaaaataa agctcgcctg caatcatttt ttctttttcg gttttgaatt
    11641 cagtcataat ctgctcctaa ttcttgtatt tttttgaaaa caaccgctcc gtcttcttga
    11701 ataaacgtat aaggctccgc taaataaaca ggcgtttgat tgattactaa gattttggct
    11761 gacggctggc gaaactgtac cagatcacaa aacggatgaa cttgaaaact cgttccaaca
    11821 atgacgatca gctctgcttg gctgacggca taagccgcct gctccatgac tccatcttga
    11881 aacccttcac catataacac gatgtctggg cgtatttgtc ctccgcatgc ttgatgtttg
    11941 tcgctgtgaa gatattcttt ccagtctacc gtttgttgac attttcgaca atgacattga
    12001 tacagactcc catgaaaatt gacgagttgc gggcttttag cctttgcgtg caaaccgtcg
    12061 atgttttggg aaacaaccca aacatttttt tctttcgcta gatgtgctat ttccaaatga
    12121 atgatattgg gttttgcttc aggatgataa atctttttga caaattgata gaatttatcc
    12181 ggttcattca ccattgcttg atgactcagc aagtattccg gctgctccat cccgtggtag
    12241 attcctgaca aagatcgata gtctggcact ccagaaggtg tggatacccc tgcaccggtc
    12301 aaaaatgtaa tttgctgata agctaatatc tcttttgctg cttcgtctac tgttaattgt
    12361 ttcatgtttt gtcacctcac tttccattat agcccatact cgaacaaatt tattgttgaa
    12421 aagtcagaaa aatgggaata aaaaagtgtt atgggcattt gagcaattta tcacaatgtt
    12481 cactgacaaa agaatgaaaa cgtgttacaa tactgctgta taaaagtgag gtgaatcgat
    12541 atgttaccat tctttattta ttggggcgtt attctggctt gtatcgcctg gttagcgtta
    12601 agcgtttatt tctctgtttt ttatcttgta cgcaaagaaa atggaaatct ttgggctttt
    12661 gctttattca acgtgattgc cgcaattgtt ttagccatta cattagccgt atatcgaaca
    12721 tggggctggg gaatcaccca atactcaagt ttgatttatc taatattagc catttatggc
    12781 gtcgttgttc ttttgcaagc gatcctagga cgtgagccaa agaaagcggc agcttaaatg
    12841 atcgagatgg aactggacac aggaaatttt ctgttctagt tcttttttta ttgtattaca
    12901 tacatttttg tgtataatta tactatcgtt tgcaatggat agatgattca cattttgatt
    12961 gttttttcgg taaaagtaaa gatttctata tttatcagta ttttttcaaa aaccagcagt
    13021 tatagattga caaagcctct cgagtatcgt aaactttttt tgtataaata actgaatacg
    13081 agatgcctca atcaatgagg tagaggtcgc gagaatcatt aaccctgtgg agtgaagcaa
    13141 acatggagaa gcaggaatag ggaggatcgc cgaaatgtgc acttttttgc ttggagtgta
    13201 tgttgggacg caagttaaga gcttgcggac tgtcttagca gtgatgctaa gttgcgctat
    13261 gttttgtgag aggtttatca ccttatggaa ttttagcggc ctttttatat ctataaatcg
    13321 gtcgcttttt attttttcag ataaagcttt accgcatttc atctagaccg ctcgtgtatc
    13381 atataatcag aaagggagaa aaaaatgaaa aaaaatatgg tttcagttgc cgtactattt
    13441 gcttttgtct tctcactatt cagtgtggga tctctggcaa atgcagatga aaaaacaccg
    13501 agcgatgagt ttcgcgtagg tatggaggct gggtatgcac ccttcaactg gtctcaacaa
    13561 acagatgaga ataatgcctt gccaattcaa ggccaaaata gttacgccgg cggttatgat
    13621 gttcaaatcg ctaaaaaagt agcagatggt ttagggaaaa aattagtcat cgtccaaacg
    13681 aaatgggatg gtctggctcc tgcccttcaa tcaggcaaga tcgacgcgat catcgccgga
    13741 atgagcccta ctgctgaacg acgaaaagaa attgatttta ccgatcctta ttacgaatca
    13801 caattagtag tagtagttca aaaagatagc aaatatgcaa aagcaaaaag tttagcagat
    13861 ctttctggag caaagatcac tgctcagtta aatacattcc actatactgt gatcgatcag
    13921 ataccagatg tgcagaaaca acaagcaatg gataatttct cagcaatgag aacagcttta
    13981 gcttctggaa tgatcgatgg ttatgtcagc gaacgtccgg aaggtgtaac ggcaactagt
    14041 gtgaacaaag acttggaaat gcttgaattc agcggtgcag atggcttcca gacaaacccg
    14101 gaagatgttc agatttctgt tggtatgcgt aaaggcgacc cggatatcca aaaagtaaac
    14161 cagattcttt ctggcatctc taacgatgaa cgaaccaaaa ttatggacca agcagtcaaa
    14221 gatcagcctg ctgcaactga tagtgaagaa aaacctggca tcatttctga tttcactacg
    14281 atttggaaac aatacggcaa tatgttctta cgaggtgctg gacttacctt gttcatcgca
    14341 ttgatcggga cagttgtcgg tactacactt ggattactga ttggtgtctt ccgttcggta
    14401 cctgaatcag gaaatgcact gactcgcttc ttccaaaaaa tcggaaatgc acttctttct
    14461 atctatgtcg aagtattccg cggaacaccg atgatggtac aagcaatggt catcttctac
    14521 ggtctggcac tcgcttttgg catttcattg aaccgaacga ttgccgcttt gtttattgtc
    14581 tctctcaata ctggagctta catgacagag atcgttcgtg gggggatttt tgcagtagat
    14641 gaagggcagt tcgaagctgc gcaagccatt ggtatgaccc atggccaaac gatgagaaaa
    14701 gttgttattc cacaagtttt acggaatatc ttgccagcaa caggaaatga gtttgttatc
    14761 aatatcaaag atacagcagt tttaagtgta atcggcgtag ctgatttgtt cttccaagga
    14821 aactctgctt ccggtgcgaa tttccaattc ttccaaacat ttacgatcgt cgggatcatc
    14881 tacttagtca tgacctttac gatcaccaga atcctgcggg cggtagaaaa gaaaatcgat
    14941 ggtccttcag cttataccaa gcttgaagaa atcgacaatt caaatttgca ggaataagga
    15001 ggaagaatca tgaatgaaaa aattattgaa atcaaacatc taagaaaaag cttcggtgaa
    15061 aatgaagtat tgaaagatat cagcgtaaca gtcaataaag gtgaagttgt gacgatcatc
    15121 ggttcttccg gttctggtaa atctactttc ttgcgctgta tcaatttact ggaaaaacca
    15181 acaggcggcg agatcattta taatggagaa aatgtattag ctcctaaata taatttacct
    15241 aaatatcgaa cgaatctagg tatggttttc caatccttca acctgttcaa caatatgaat
    15301 gtcttggaaa actgtatgtc tggtcaaaca actgtcctga aacgagataa agaaactgcc
    15361 aaaaaagtag caatcgaaaa tctggaaaaa gttggtatgg atcgttatat cgaagccaaa
    15421 ccagcacaat tatctggtgg acagaaacag cgtgtcgcaa ttgctcgggc attatcaatg
    15481 aatccagatg tattgctatt cgacgaacct acttcggcgt tagaccctga aatggttggc
    15541 gaagtgctta atacgatcaa agacttagca catactggct tgacaatgct tatcgtgacg
    15601 catgagatgg aatttgcaaa agatgtatct gaccgtgtca tttttatgga taaaggtgtg
    15661 attgcagaag aaggtacacc agaagatatc tttgtccatc cgaaagaaga acgtacaaaa
    15721 gaattccttt cacgtatttt aaatgcttag gatcaatagc tgattgggac aaagagctgc
    15781 ggtgtttacc gcagttcttt tttatgaatt actcataaaa ggtaaatttc
//
LOCUS       DAZAOD010000059        15667 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000059 DAZAOD010000000
VERSION     DAZAOD010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.060"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            167..733
                     /locus_tag="ACHDPO_001877"
     CDS             167..733
                     /locus_tag="ACHDPO_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3369493.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            878..965
                     /locus_tag="ACHDPO_001878"
     tRNA            878..965
                     /locus_tag="ACHDPO_001878"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:910..912,aa:Ser,seq:cga)
     gene            1301..2275
                     /gene="bsh"
                     /locus_tag="ACHDPO_001879"
     CDS             1301..2275
                     /gene="bsh"
                     /locus_tag="ACHDPO_001879"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFN3369494.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            2600..4495
                     /gene="asnB"
                     /locus_tag="ACHDPO_001880"
     CDS             2600..4495
                     /gene="asnB"
                     /locus_tag="ACHDPO_001880"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFN3369495.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(4690..5136)
                     /locus_tag="ACHDPO_001881"
     CDS             complement(4690..5136)
                     /locus_tag="ACHDPO_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFN3369496.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            5364..5513
                     /gene="rpmG"
                     /locus_tag="ACHDPO_001882"
     CDS             5364..5513
                     /gene="rpmG"
                     /locus_tag="ACHDPO_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFN3369497.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            5601..6119
                     /locus_tag="ACHDPO_001883"
     CDS             5601..6119
                     /locus_tag="ACHDPO_001883"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFN3369498.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(6196..7152)
                     /locus_tag="ACHDPO_001884"
     CDS             complement(6196..7152)
                     /locus_tag="ACHDPO_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369499.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            7318..8124
                     /locus_tag="ACHDPO_001885"
     CDS             7318..8124
                     /locus_tag="ACHDPO_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369500.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8121..9110
                     /locus_tag="ACHDPO_001886"
     CDS             8121..9110
                     /locus_tag="ACHDPO_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFN3369501.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            9107..10111
                     /locus_tag="ACHDPO_001887"
     CDS             9107..10111
                     /locus_tag="ACHDPO_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFN3369502.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            10243..10785
                     /locus_tag="ACHDPO_001888"
     CDS             10243..10785
                     /locus_tag="ACHDPO_001888"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFN3369503.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            10805..11503
                     /locus_tag="ACHDPO_001889"
     CDS             10805..11503
                     /locus_tag="ACHDPO_001889"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFN3369504.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            11524..11736
                     /locus_tag="ACHDPO_001890"
     CDS             11524..11736
                     /locus_tag="ACHDPO_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFN3369505.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            11736..12698
                     /locus_tag="ACHDPO_001891"
     CDS             11736..12698
                     /locus_tag="ACHDPO_001891"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFN3369506.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            12716..13111
                     /locus_tag="ACHDPO_001892"
     CDS             12716..13111
                     /locus_tag="ACHDPO_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFN3369507.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            13274..13639
                     /locus_tag="ACHDPO_001893"
     CDS             13274..13639
                     /locus_tag="ACHDPO_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFN3369508.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            13636..15447
                     /locus_tag="ACHDPO_001894"
     CDS             13636..15447
                     /locus_tag="ACHDPO_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFN3369509.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(15509..>15667)
                     /locus_tag="ACHDPO_001895"
     CDS             complement(15509..>15667)
                     /locus_tag="ACHDPO_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFN3369510.1"
                     /translation="FVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEENRKK
                     AMRKRVSR"
BASE COUNT         4884 a         2632 c         3279 g         4872 t
ORIGIN      
        1 ggaacccatt gaatttaacc aaattttttt aattttgcaa aaaaaagtta aagaagactg
       61 aaaaaaattt aaaatataac gttttgagta aaatgtttgc aaaaaatgct aaaaataggg
      121 tacaataaaa caacatatac tgcagtaaag aagtggggga gttttaatga gaagaaaagt
      181 ctataccaag gatcaaattc taaaagctgc ttatgatgtt gttgcaaagg aagggtttaa
      241 aggatttact gcgagaaata ttgctaaaaa gatggggatt tcgacacagc cgatttatct
      301 ggaattcaaa aacatggaag atttaaaaaa tacgttgctg gattctatct ttgaacaact
      361 aaaagaagat gttttcccta ttgaacgtac tggtgataaa atcattgatc tcggtttgaa
      421 ctatatctac tttgcaaaaa agcatcatag tctttacatg gcattgtaca ttgatgaaca
      481 tggggacgga aagaaaatgc atgatttttc atacaattat ttccgtgaaa tagttaaaga
      541 agatgaaaga tacaatcaat tatcggatga atatgtcgat gctctgcata ctggtacatg
      601 ggtagcagtg actggcttag cgtcattgat gtcatcaaac atcatgcatc caacagaaga
      661 acaaatcatt gcactgatca aacggacaat tgactcgatt ttagcattag ataatcctga
      721 aataatcaga tagtgttcta tcagtatgaa tttgatcggt aagtccgttg gctgcaaact
      781 gtcaatggac ttttttgcta aaaaaagcga tttctgttat ttatctatta gaaataggct
      841 tgacatttcg tgaaaaaagt ttaaaaatag tacttacgga aggttggcag agtggtaatg
      901 caccggactc gaaatccggc gaaccggcta ataccggcgc gcaggttcaa atcctgtacc
      961 ttccttatat caacgattag aggttgtgaa gaagctgtcc tgcatcaagt aataagaacg
     1021 gccaaacaaa aatagctttt cctatttttt cgtttggttg ggcttattac cgcagatgca
     1081 agcttttgaa caccgtttgt tcggaataag gggctgtgac aagacttttg tcacagcccc
     1141 ttattgttgt acttttaacc tacaatattt tttgattccc cctgagtact attttttata
     1201 aatgctagta aatcaatctt ctttggcctt ttttttgata aaaaaaaata ctagatgtaa
     1261 gataaaagtg taaaaacgat ttgttttagg agggaaaacg atgtgtaccg caatcactta
     1321 tgcaacgaaa gaccattatt ttggaaggaa ttttgattat gagatgtctt ataatgaagt
     1381 agtcactatt actccaagaa attatcgttt cgattttaga aaggtaaaaa atttagataa
     1441 acattatgca atgataggaa tagcagctgg ggtatccaac tatccactct attatgaggc
     1501 tacaaatgaa aaagggttga gtatggcagg actgaatttt cctggcaatg ctgattataa
     1561 agaattacaa gaaggaaaag ataacgttgc accatttgag tttattccat ggatactagg
     1621 gcaatgctca accatagacg aagctaaaga attattggct actatcaatc tagtcaatat
     1681 cgattttagt gaaaaactac ccttgtcacc tttacactgg ttattagctg ataaagaaaa
     1741 atcgatagta attgaaagta tgaaagatgg acttcattta tatgataatc ctgtcggtgt
     1801 gttgacaaat aatccgccat ttgattatca attatttaat ctgaacaatt atcgctcgct
     1861 atcaaatgga acaccagaaa atcatttttc aaaccagatc agcttgaatg tttatagtcg
     1921 tgggatggga ggattgggct tacctggaga tctctcttct gtttctcgat ttgtaaaagc
     1981 cacatttact aaaatgaatg ctgcatcagg tgattcagaa tctgaaagta tcagtcaatt
     2041 ttttcatata ctaggctcag tcgagcaaca aaaaggagta tgcgatactg gagaaggaaa
     2101 atacgaatat acgatttatt cttcttgctg taacgttgat aaagggattt attattatcg
     2161 tacgtatgaa gacagtcaaa ttactgctgt aaatataaat aaagaagact tggatcgtca
     2221 tgaattggtc agttatccag tcataaaaga gcaacagata aactatgtca attaattaat
     2281 gaatagatcc gtttggtatc atattttctg atacagtcat aattagacac gatctttagg
     2341 tcgtgtcttt ttttgctgtt ttttttggaa atagcatcca ctaatatttt tttaacacga
     2401 agagaataag gtagcctcaa aaaagaaaac atggtaaatt agatattggg actttatttt
     2461 ctgtaaaaac agaaactttc atcttttgtt ttcacgtgac gaaattgtaa gagagaaaat
     2521 attcgtccgc tatttattct atgataagat gcatatgaat gaaataaaca gtaattttat
     2581 attaggatgt gaaagttaaa tgtgcggtat tgtaggtttt gttaacgaca aggacaacaa
     2641 aaaaacaatt attaatacaa tgatggatcg aatcgttcac cgtggaccta atagttcagg
     2701 agaatatatc gataaacatg ttgctttagg attcagaaga ttaagtatta ttgacttaga
     2761 gggcggtact cagcctattt acaatgaaga tcggacaaag atcattattt ttaatggcga
     2821 aatctataat taccagcctt tgagagaaga attgattgca gctggccacg tttttcaaac
     2881 acatgcagat acagaagtcc ttttgcatgg ttacgaagaa tggggaacag aattattgca
     2941 aaagatccgc ggaatgtttg cttttgctat ttgggataat gaaaagaatg agttattcgg
     3001 tgcaagagac cactttggga tcaaaccata ttattatgca gaaatgaacg gaacatttat
     3061 gtttggttca gaaatcaaaa gttttctgcc tcatcctgat tttaacaaag aattgaacaa
     3121 agaagcgttg aaaccttata tgactttcca atattctcca ttaaacggcg aaacattctt
     3181 caaagatgtc tatcgtttgc ctgaaggcca ttattatacg tataaagatg gaaaactaga
     3241 cattcagcaa tattgggatg cagattttga aacaaaagaa acgcattccc gacaagaatg
     3301 gatcgaaaaa atcgacgaaa ccgttcaagc ttctattgaa gcacatacgg tcagtgatgt
     3361 agaagttggt tctttcttat ccagcggggt tgattccagt tatgtaacct ctgtattgaa
     3421 accagatcat tctttctcaa tcgggtttga tgataaaacc tataatgaag cgattgaagc
     3481 cagaaaacta accgaactat tggacttaga taatacagca gcagtgatcg acggagacat
     3541 gtcgttcaaa gcattccctt tgatccagta tcacttagat gaacctgatt caaatccttc
     3601 ttgcgtacct ttgtactttt tagcaaatct tgcttcacaa agtgtgcggg tagtccaatc
     3661 tggagaaggg gcggatgaac tgtttgcggg ataccaaacg tatggattcc atacgaattc
     3721 aaaattcatc cgtgtgattg ctcaaggatt gaaaaaatta ccaaaaggaa cacgctataa
     3781 tttaggacgt aaaatcggaa aaatgaaaaa tttccatgga cggatccatt tatatgaatc
     3841 acttgctcct gcaaaagaat attttatcgg tcatgctcga gtgttcgaag aatcagaagc
     3901 atcagaagtg ttaacaccaa aatatcaaac agcaccatct gtggatgaaa tcatgactgt
     3961 tcattacgag aaaacagaag gaatcaaaga tgaagtcaat aagatgcaat atgtcgatct
     4021 tcatcaatgg atgccaaaag atatcttgtt aaaggcagat aaactttcta tggcaagttc
     4081 tttggaagtc cgagtacctt tattggatat cgaagtcatg aaattggctc aacaaatacc
     4141 aagtaagttt ttattgaatc aaaacaacac aaaagatatt ttcagacaag ctgcgaacaa
     4201 acatcttccg gaagaatggt cgaatcgtgt gaaattagga ttccctgtgc caatcaaagc
     4261 ttggttgaaa gaagaacacg gctacgaaca agtcaaagca ttattcgaag cagattttgc
     4321 aaaagaattt tttgatcaag aaaaaatcat gaagttgcta gatgaccatc acgaaggacg
     4381 taaagaagag caaagaaaaa tctggacaat cttcagtttc ttgacatggt ataaagtcta
     4441 ctttgtagat gaaacgattc cgcaagcaga agcaatcgac tatgtgactg tttgatgaaa
     4501 atcaaatatc aataaaaaag aggttttctc ctaccgttta acactgagtg ataagaaaca
     4561 atttcaaaaa acagctcttc ccgttttata gatattatga cttatggttc ggagttggca
     4621 gaggaacacc attgtttcga acataagggg gttgtgacac gattttcgtc acaacccctt
     4681 tacatatgtt caataatcga tttctttttc ttttgtccca tcttttttat aaatgaacaa
     4741 agttgattct ttgttttgtg ctacttgctt tcctttttcg attgcttctt tttttgtatc
     4801 aaaatggttg cttgcctttt ttgccccttt agatttcacg atccattgtt cttcctcata
     4861 ttctacgatc acatctgaat caagcagttt tccagcacga ggattcgtat cgtgttcatc
     4921 cgtcttgctt ggattttttt ctttttcgaa agttcgtttt tctgattcac tagcatcttc
     4981 ataccatttt tttgcttgat caatggcaat tgggatcgca cggttatcag ggtacccttc
     5041 atctaataat gcatttgcga tgtcgattgc tttttttctt gtcaatttat ctaagttttt
     5101 cattgatgca ggaaagtcct tcatgttcca tggcatatta gtatccccct ttattaaaaa
     5161 acataatcta tataaacaag tgtaagggta tttatacaaa aagaaaaaga ttttgtttga
     5221 gaagtaaaac cgttgtattt atcgtcaagt agttttactt aacaaaatcg tgaaaaacac
     5281 tagcaatcta gaaaaaatca tggtaagata atcaagtctg agagtcatct tagaggattc
     5341 ttgtaaaaat gggagggaaa aacatgcgcg taaacatcac tttagagtgt acttcttgta
     5401 aagaacgtaa ctatctaaca agcaaaaaca aacgtaacaa tcctgatcgt ttggaaaaac
     5461 aaaaatattg cccacgcgaa cgcaaagtta ctttgcaccg tgaaacaaaa taatgttttt
     5521 aaagttctca attccttgct ggtcaaagaa ttgagacttt ttttatctca aaacatctaa
     5581 aatcataagg agcggataat atgtttattt ccatgtgggc acaagataaa aatggtctga
     5641 tcggcaaaaa tggtttgtta ccatggcgat tgccaaatga tatgcgtttc tttcgcgaac
     5701 atacaatgga tcgaatttta gtgatgggaa gaaagaccta tgaaggaatg ggggatcttt
     5761 cacttcctta tcgccatatc atcgtgttga caacgcaacc aaattttcgc acgaaagaaa
     5821 atgcggaagt aatgcattcg atcgatgaac ttttgtcgta tagtcaaacg atctcagaag
     5881 atatctatgt ttcgggtggt agtcggattt ttcaagaact tcttccttac actggtcgga
     5941 tctggcgaac attgatcgat agcacgtttg aaggcgatac gtatattggg aatattgatt
     6001 tttcagactt cgcccttata gaggagtatg aggggataac ggatcaagaa aatctatatg
     6061 cccatcgttt tcaaaaatgg gaaagagtaa aaaatagggt tgcttcaaaa gaagaataaa
     6121 atctatgcgt ctagtttgtt aataagaaaa aaagcatctc acgactaatc gtgaagattc
     6181 tttttttagt taaaatcaat ttagtttttc tttgatatca ttgaccattt cctgactggc
     6241 aataggtccg ttatatagcc aactagattc aggtccgaat tgcagtacat gattgtctgt
     6301 cactgcttta agattcttcc agcttggttc attgaacatg gcagcatctt tgtcactgtt
     6361 cacaaggatg atgtagtcag catctaattc agctagcttt tcagaggaaa cagcagacca
     6421 gtcagaagtg gcttttttgg agacctcttc cactagatca ggaacaccaa attccagatc
     6481 gtcgtatacg attcttccac ttgaccgatt tttgctgacc ataaaggctg agttgttggt
     6541 cacccacaac actgcagctg tcttgttctc gattttatct gctagttctt ctcgagtttt
     6601 cttgatggat ttttgataat cggaaatgat tttttctgcc tctttttctt ttgccaaagc
     6661 tttgccgaca tcttttagtt gttcttccca tgtgacatct gttccgtttt ttacaacata
     6721 agttggcgcg attttgctat attgttcgta tttcccgcct tcgacagtag cggaagaaga
     6781 aatcaacagc aaatcaggct caaagcttaa cactttctca taaggaaggt cataagaaat
     6841 cgttgggaca tcctttaaat catcttgcag ataatcttga atggaaccac tgccaacagt
     6901 ccactgggcg ataggttttt cccctagtgc aatcagatag tcttctaagt aactgccgat
     6961 gatccgtttg ggcgcgtttg gaatctctac tttatgtcca agtgtatctg tgactgtatg
     7021 agtactattg gatgaagtcg tcgaattggc agttgtagct gtttctttat ctgaagaggg
     7081 ggagcaagcg ctcagtactc cagccagcag caatatgcta gataatgtga atacttttgt
     7141 ttttaatttc atttctttcc tcctaacata attgagaatc tttctcattg gttattattc
     7201 ctgatatttc gaacgctgtc aaccgcttca tttggctata gatatgaaag tagcgcttga
     7261 cgaaatgttg aaacagcgtc ataattgaga atgattttca gcgaaaggat gggtgaaatg
     7321 acgagattaa gagcagctga cattgcagcc ggctacgaaa acaaaaaaat cattgaaaac
     7381 atgtctgtta cgattcctga agggaaaatc actagtttga ttgggccaaa tggaagtgga
     7441 aaatctactt tattgaaaag ttttacccgt atactacctg tgaaatcagg aaagatcatt
     7501 gtcaataact ctgatatctc tacatacagt tcaaaagaac ttgcaaaaaa aattacatta
     7561 ttagcacaaa ctagtgaaca ccctacaggt atgacagtag aagaagtagt atcttacgga
     7621 cgataccctt atcaaaaact gttcagtggc atggacacgc aagatcatga agcaatcgag
     7681 tgggcgttgg atgctacagg tctagctgga tttcgtatgc gggatatcgc aacgctgtct
     7741 ggtggacaaa cccagcgtgt ctggatcgct atggcgcttg ctcaggaaac agatatcttg
     7801 atcttggatg aaccgacaac atttttagat ccggcacacc aattagagat cctacagtta
     7861 ttgactgaaa tcaatcaaat gaaacaaaca acgatcttga tgtcgattca tgacattaat
     7921 catgcttcac gtttttcaga ttatttatta gcaatgaaaa acggtaagtt gatcacagaa
     7981 ggtacacctg aagaagtgat cacaaaagag tgtatgaaaa aaatatttga gattgatgca
     8041 acgattgtca cgcttccaag aacaaataaa ccagtttttc taacctatga tttgttgcca
     8101 aaagagcagg aggatcaatt atgaggacta tgaagaaaaa tagactcctg cttttggtct
     8161 gttttgttct tttgattatt ttttttgttg ctctttcaaa tggcgcagcg actgtgggaa
     8221 aagcagattt ttggcaggcg ttgtttgatt ttgatagatc aaaacaaagt caccaaatca
     8281 tacgaaatat tcgtttgcct cgtgtggcgg gagcatttct tgtagggagt tgttttgcat
     8341 tgagcggtgc attgatgcaa ggagtgacaa gaaatccttt agcagattca ggcttactag
     8401 gaatcaacgc gggtgcttcg ttggcaatgg cccttagttt tgctttttgg cctaaagctt
     8461 ctgatttttc tgtgtttcta atgtcattgg caggttcttt tgctgtaact ttgctcgtat
     8521 ttggtttttt gcagttttcg aaaatgggca tgaatccttt acagctgatt ttagctggcg
     8581 tagctattag ttcttttttt actgctatca gccaagcact tacccaattc tttaatctgc
     8641 agcaggatct tgctttttgg tttgtaggcg gagctgccaa tatcacatgg aaacaattag
     8701 cagtattgtt tcctttatat atacttgctg ttttggtttc tttttcatta ggaaaagcaa
     8761 tatctttgat tcatttgagt gaaacacatg cattagctct tggaagtcat cctaaacgaa
     8821 cgcggttgat tgttttctgt ctagttgcag tgttagcagc cattgccgtt tcgttagtcg
     8881 gacctgtttc atttattggg ctgttggttc cgccagttgt tcgcggaatg gttggaacgg
     8941 actatcgtta tgttctacct gtctcttttt tagttggcgg tggattggtt atgttggcgg
     9001 attttacagc gaggatgatc aatccccctt ttgaaacacc ttttggatta gtcattgcat
     9061 tgattggcgt tccgttttta ctgatacaag taaggaggga acaacggtga aaaaaatata
     9121 ttggacgttc tatttcttgc tttttgtact tgtcatcctg tctataggta gtttaatgat
     9181 tggtacgcct tttatttacc tggatcagct ttttgccacg ttcataggga aagaatcatc
     9241 ttctttggcg ctgattgtta gagaatttcg agttcctcga ttactgatca gtttattagc
     9301 aggagcttgt cttggcgttt ctggttatat cttgcaagga gtaacaagaa atgaattggc
     9361 agattctagt atattgggca ttaatgccgg agcaggattt ttagtgatgc tttatttagg
     9421 tttcttttcg cactattcgc tgccgtttct attgctagtt gtagcctttc taggtggtgt
     9481 tttagctgct tgctgtgtct atcttgcggc ctatgatcga aatggctttt tgggtatgaa
     9541 tcgaatctta ttgtccggta ttgccgttaa tgccggcctt tctgcattaa cattgctatg
     9601 cacgatccaa ttatctaagg aaaattatgg atttgtgaat gcatggttag cgggatcaat
     9661 ctggggtgcg agctggcctt atgtttgggc attgcttcca tgggcggtta tcttaattcc
     9721 gctaggagga ctttatgcac agaggattgg attgctatca tttggtcaag aacgcgcgca
     9781 aggattaggc cttaacgtgg ctaaaagtca aaaaatcctt ttgttgttag ctgttgcttt
     9841 ggcaagcggt agtgtagcgg tgacaggtag tttatctttt gtaggactac tagctcctca
     9901 tgctgcgaag ctggtcgtac gtaaagaaaa taactggacc tttgttctga gcggtttgtt
     9961 cggttccatt tttctgctta gtgcagatat ggttgctaga gtgattctac caagtgggga
    10021 agtacctaca ggaattttga ttgccctttt tggtgcgcca tattttctgt atgcactttt
    10081 tatcagacaa aaacacgcgc tgaacagttg aaatttatta aaaaaggaag gccaatcatt
    10141 tctaggtctt ctttttattc tatttatgca tttatttgaa agttcgattg ctatttttct
    10201 ttttttccta taccatttta tgagagaagg aagggtgagt ttttggacca attgaaagta
    10261 agattacgcc ggaaaggaat cgaaaagctg aaaaatctgg ccaaaagtgg caagaaaaag
    10321 gaaaaagaac agcgaatcta taaacagcta ttcgccagcg agtactggaa gtcagcaaaa
    10381 gtgataggga cgactttatc gaatgaattt gaactggata cacagccggt tatccaacga
    10441 gcagaaaaag aacaaaagaa aatagttgta cctaaaactt tgccgaaacg tcagatggcg
    10501 ttttatgaaa tggatgaaca gtccgttctt gtacgttcga gttttggtgt tcttgagcca
    10561 caatcagaga agctctattt gccggagatg atcgatctcc tcattgtacc aggtattatc
    10621 tacaatagag ccggttatcg aatcggtttt ggcggtggtt attacgaccg gtatttaaat
    10681 aattttcata aaaaaacatg tagccttgtt tttcgtgaac aattgaatga acaatggcaa
    10741 ccggagagct ttgatcagaa gatccaacaa ttgtttattg actaaaatga aatgggaggt
    10801 tttcatgaat tatcaacagc aaataaaatt gcgtgcatgg ttaagacgac cgttatggac
    10861 ctatgctttt ttagggatac agacagcggt cttcctcatg atggaattat ttccgcgact
    10921 tgagatccct tattatgccg gaatgtatgg tccttatctt gttcacttca atgaatggtg
    10981 gcgtttagtg acaccaatct tcatccattt tggactgatg catttcgtaa tgaactcact
    11041 gatactgtat tttatggggc agcaaatcga ggcaatctat ggccattggc gttttttctt
    11101 gatttatatg ttcagcggga taatgggaaa tacagcaagc tttgctttta acgaagcgaa
    11161 tgttctgtct ggtggtgcga gtacttcgat attcggtttg ttcggtgcgt tgtttatctt
    11221 agggtttcat tttaaacata acccagcgat ccagcagcta gtcagacatt ttcttttatt
    11281 tattgtgttg acatttgttt ttggtcttct ggatacctct gtagatgttt ggggacatgt
    11341 cggtgggcta attggcggat tagtgttagg gaatgttttg ggtctaccga aacaacagac
    11401 aagctattcg atacaccaaa ggattctttc tacactagtt tttgtatttc tttttgtaat
    11461 atgtatttta ctgggtttaa aaaaatatgg tttacttgta taatatgaag gaagtgctta
    11521 aagatggaga gcttatatga tgtacagcag ctgttcaaaa aatttggcat ctttatctat
    11581 gtgggtgcac gcatctatga cattgaatta atgactatcg aattgcgtaa tctgtatgat
    11641 agccgtttga ttgatcatga tacatacatg acagcgtggc gcatattaaa aagagagcac
    11701 cgaattgaag aaagccgaaa gaaaggaaat ttgtaatgga caagaagatt attgggattg
    11761 atttaggtgg aacaacagca aaatttgcaa ttttaacacc agaaggagag attcaacaaa
    11821 aatggagcat cgataccaat attttggatg atggtaagca tatcgttcct gaaatcattg
    11881 aatcaatcaa ccatcgtttg aatttatata atatgaaagc cgaagacttt atcggaatcg
    11941 gcatgggtac cccaggaagc gtggacagcg aagctggaac ggttattggt gcgtataact
    12001 taaactggac agaagttcaa tttgtgaaaa aactgatcga ggcaggaaca ggaatcaaat
    12061 tcgctatcga taatgatgcg aatgttgctg ctttaggtga acgatggaaa ggtgctggag
    12121 aaaacgatcc agacgttgta ttcgttactc taggaacagg tgttggcggt ggtatcgttg
    12181 ctggcggaaa tttgattcac ggcgtgagcg gagcaggcgg agagatcggc catatcactg
    12241 tggatcctga agggttcgaa tgtacttgcg gtaaacgcgg atgtttagaa actgtgtcta
    12301 gcgctactgg tgtggtacgt ctaggtcgtt acttggcaga agaatacgca ggagattcaa
    12361 aactgaaagc aatgttagac aacggtgaag aagtaacaag taaagatatc tttgaaatgg
    12421 ctcaagaaga cgatccgttt gcattgatgg ttgttgatcg cgtatgcttc tacttaggtt
    12481 tagcttgcgc caacttgggg aatacattga atccgtcaag tattgtgtta ggtggaggag
    12541 tatcggcagc aggagaattt ttacgtagcc gtgtagagaa atattttaaa gaatttactt
    12601 tcccgcaagt aagagaatca acaaaaatca aattagcaga gcttggtaat gaagctggtg
    12661 tcattggtgc tgcctcatta gccttgaaat ttgcttaaaa aaacggaggc attacatggt
    12721 tttatgggta attaatatca ttttgctatt gattgtgctt gcaatcatct tttgggaagt
    12781 ctatctacga gtaatggcca agcgttcagc aacgactttg acagaagaag aatttcgaga
    12841 aggaatgaga aaagcacaag taatcgatgt tcgcgaaaaa gatgtgtttg atgctgggca
    12901 tattttaggt gcaagaaaca tcccttacac tgttttgaaa gattcattag gatctattcg
    12961 aaaagaccag cctgtctata tttacgatca aaagaaaagc ttgagcatcc gtacagcaaa
    13021 taaattacgt aaagcaggtt atcaagagat ttatttactt aagggtggat atgacggatg
    13081 gtctggaaaa atcaaaagta aaaaagtata aaacagatga ttgtatgaca gctttaaaaa
    13141 ccgaatcaat cattagattt tgaccaagat cacatgaacg gcgcaatgga tagttgtgcc
    13201 gttcattttt tttattttgt gctattatct acatatataa gctaagcgaa aaggcagaaa
    13261 gaaggaaaca actatgatca aattaaaacg tgtttacctt gatgctgaaa aagaggatgg
    13321 ctatagaata ctcgtggata ggttctggcc acgaggaatt tcaaaagaaa aagcgcagtt
    13381 agatctgtgg ttgaaagaaa ttgcacctag taatgaagca cgcaaaactt ttgaccatgt
    13441 accagaacga tttgcttcat ttgcaaagaa ataccagcaa gaattgattt tcgaagaaga
    13501 aaagaagcaa gctattttta aactcagtca acttatgaaa gaacatccag tcattacttt
    13561 tgtttatggt gcaaaaaatg aacatcagaa ccatgctgtt ttattgaaaa aatttatcga
    13621 aatggaggca tgcaaatgaa aatagggatc attggtgccg gacctagagg attaagtata
    13681 gcagaaagga ttctccataa taatcaggac agacattctc ttgaactttt tcttttcgat
    13741 cccaatggtc ctggaggtcg agtttggcgg ttgaatcagc caccggagtt attaatgaat
    13801 tctgtttctc aacaagtgac gctttttaca gatgaaacat tgtccagtgg aggattggta
    13861 acacagggac ccaacttgtt tcaatggagt aaaggacctg ctacagatta tatcgaacag
    13921 acggtaacca aaaataagca actaattata gaagaaatca atcgtctgga aaaagatcag
    13981 caatctactc gatgtttata cggactctat caacgctggt ttttctcaaa gttgcaagaa
    14041 gaatttccag cttctattca gtttgtttat tctttagtaa aaaaagtcag caaaagaaaa
    14101 gatggttatc ttttacagac agatcagcaa agctattcta tcgatcagct tgttttagca
    14161 agcggtcact gggaaaatga tgagacagaa gaagaaagag tgtgggtaga ctacgcaaag
    14221 aaaaatgatt tactgtatca gcttccttct aatcctgcag atgtcgatct ttcgaagata
    14281 ccgcctaaag aaaatgtctt tttaagaggt ctaggcttaa gtttttttga ttatgtcgga
    14341 ttgtttacag tatcaagaga agggcgcttc gagaacgaaa aaggaaaact tgtctatcat
    14401 ccatcaggca aggaaccgat tgtatacagt ggatcaagaa gggggctccc ttattaccct
    14461 cgaggaagaa accaaaagca aggcggatca atggcatggc cacggttact aacaaaagaa
    14521 aacctggagc aatggcatca gtcgggattt ttgactggcg aaacattttt tgactatctg
    14581 aaaaaagacg ttgagttgtt ttattacaag aaaatcatcg aagaatatca tttgccgatt
    14641 ccaaagaaaa attttgagca tgattttctc tccctctctt cagaggagtg tctcggaaag
    14701 catccagcac taatccctta tagatgggat tggtcgtatt tagaaattcc tcttacctat
    14761 caggatgagt cctttgcaga agctagccga gcatttattg aagggcagat aaaagaagcg
    14821 gaaaaaggca attgcacagg agcatttgct tcaacatttg atgcattaaa agactggcgt
    14881 gatccaatcc ggcaggctat tgaatggcac gttttttctg caaaggaata caaagaaata
    14941 ctatggggat ggtttactca tctaaatagc tttttaacga tcggtccgcc agtcattcgg
    15001 acgaaagaat tagcagcact gatagatgcg ggtatttttc atttgttcga accgccattt
    15061 gatattcagc aaaagcacaa ccgctatgtt atttctctac aagataaaga aatcagcagt
    15121 cgctatttga ttgaagctcg attgccacaa acaagctttt ctcgttcaag taatcctgtc
    15181 ataaaaaatt tgaaggaaaa caaacttgtt cgcccttttt cattttcaga taatacagga
    15241 agttatcatt cagaagctat agatgttgag cgaggtacga atcgcgtgat tgatgcttca
    15301 ggggaaatcc agtctgactt ttattgctat ggaatacctg ttgaaggtgt ggattggcta
    15361 actgcagcag tagctagacc ttatacagat ccatggaatc tgagacaggc agataaaata
    15421 gcacaactta tattgactga caaataaaaa tacgcatgat gacttatctg ttctttcaca
    15481 agtcttcatg cgtgttttta aataattatt aacgagaaac gcgtttgcgc attgcttttt
    15541 tacggttttc ttcgatcatt gcttcttttt cgtcaattgg atcgatcact gtttttttca
    15601 cagaagcgac caaaccagca acggcagcgg ctgttgccag acttcctact aatattccag
    15661 atacaaa
//
LOCUS       DAZAOD010000060        15387 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000060 DAZAOD010000000
VERSION     DAZAOD010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.061"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            21..299
                     /locus_tag="ACHDPO_001896"
     CDS             21..299
                     /locus_tag="ACHDPO_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369511.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            318..1526
                     /locus_tag="ACHDPO_001897"
     CDS             318..1526
                     /locus_tag="ACHDPO_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3369512.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(1674..2039)
                     /locus_tag="ACHDPO_001898"
     CDS             complement(1674..2039)
                     /locus_tag="ACHDPO_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFN3369513.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(2186..2959)
                     /locus_tag="ACHDPO_001899"
     CDS             complement(2186..2959)
                     /locus_tag="ACHDPO_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFN3369514.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(3133..3993)
                     /locus_tag="ACHDPO_001900"
     CDS             complement(3133..3993)
                     /locus_tag="ACHDPO_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFN3369515.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(3993..5411)
                     /locus_tag="ACHDPO_001901"
     CDS             complement(3993..5411)
                     /locus_tag="ACHDPO_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFN3369516.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(5468..5917)
                     /locus_tag="ACHDPO_001902"
     CDS             complement(5468..5917)
                     /locus_tag="ACHDPO_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3369517.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(6362..6625)
                     /locus_tag="ACHDPO_001903"
     CDS             complement(6362..6625)
                     /locus_tag="ACHDPO_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFN3369518.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(6724..8019)
                     /gene="rho"
                     /locus_tag="ACHDPO_001904"
     CDS             complement(6724..8019)
                     /gene="rho"
                     /locus_tag="ACHDPO_001904"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFN3369519.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(8016..9287)
                     /locus_tag="ACHDPO_001905"
     CDS             complement(8016..9287)
                     /locus_tag="ACHDPO_001905"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFN3369520.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(9452..10321)
                     /locus_tag="ACHDPO_001906"
     CDS             complement(9452..10321)
                     /locus_tag="ACHDPO_001906"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFN3369521.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            10424..10636
                     /locus_tag="ACHDPO_001907"
     CDS             10424..10636
                     /locus_tag="ACHDPO_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369522.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            complement(10613..12223)
                     /locus_tag="ACHDPO_001908"
     CDS             complement(10613..12223)
                     /locus_tag="ACHDPO_001908"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFN3369523.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(12445..12690)
                     /locus_tag="ACHDPO_001909"
     CDS             complement(12445..12690)
                     /locus_tag="ACHDPO_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369524.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            complement(13416..14756)
                     /gene="glnA"
                     /locus_tag="ACHDPO_001910"
     CDS             complement(13416..14756)
                     /gene="glnA"
                     /locus_tag="ACHDPO_001910"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFN3369525.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(14784..15176)
                     /locus_tag="ACHDPO_001911"
     CDS             complement(14784..15176)
                     /locus_tag="ACHDPO_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFN3369526.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         4376 a         3276 c         2643 g         5092 t
ORIGIN      
        1 taagaataga gggaaaaaac atgaattact ggatgaacac aatcattaat cgattagaaa
       61 cagcatatca aacaagattt gatatgaaag cttctttagt ctttttaaat gatgcgtatc
      121 aaaactcgat cgaattgatc aaagcagtgg atgagaatcc aacaaacgaa tgcgaagaat
      181 ttttaaatct gtttatgtct acaagagatt tatttattcg ccaacttgtt gatcgctatc
      241 catccaatta tcacgatgta gaagttcaaa tacaaaaatt aaaagcatat tcagcttaag
      301 gggaatgtat aacatacatg gaaaagaaat tatttaataa atattttatt ggaatcacat
      361 tgatcaattt tattgtctac ctgatttatt atctgttgat ggtcatcatg gcagtcattg
      421 cgcaagacac cttacacgcc agcttgagcc aagcaggttt tgcttctggg atctatatca
      481 tcggaacatt gctggcacgc ttattcatgg ggaaacagtt agaactattt ggtcggaagt
      541 ttaccttaag aggcggcgcg atcttctatc tcctttcaac attagcatat ctttatacgc
      601 caactatcgg ggcattgtat ttagttcgat tcttgaatgg attcggctac ggtacagttt
      661 ctacagctac aaatgctatc gttactgcat atatccctgc atctaaaaaa ggggaaggca
      721 tcaattatta tggattaagt actagtttag ctgccgctgt tgggccattt ttaggaatga
      781 ttttgctgaa tatgactgat tttcgtttca ttatctggtt ttcaattgta ctggtcttct
      841 ttgttacgat tgcctgcctt gtctttcctg taaaaaatat tccattatct gaagaacaaa
      901 aaatatctct tcgctcatgg aatatcaata gttttattga aaagaaagca cttttcatta
      961 caggaattgc ctttttgatg ggtctttctt attcaagtgt tttatcattt ttatcttctt
     1021 atacaaaagt aatccactta gttgctgctg ggtcattttt cttcgtcgta tatgctttgg
     1081 tcatcacatt tacacgtcca ttgactggaa ggattttcga tgtcaaagga gaacaatacg
     1141 tgatgtatcc tagctattta ttcttaacag caggattatt tttactgagt gtaacgacga
     1201 atagtgtgac attgcttatc tctggagcat tagtcggcct aggttatggt acgtttatgt
     1261 caaatggaca ggctgtttgt ttaaaaatcg tccgcgaaca tcgaatcagt attgctttat
     1321 ctacctactt tattggttta gacctaggct taggcgttgg tccttatttg atggggatgc
     1381 taaaatctct tacttcattt agaggattgt atgtgattgc cggagtcatt ccattgatat
     1441 gtacagcact ctatcttgtt aatggccgaa aacatagtca tgaagcagag ggcgaattga
     1501 ttgaatcatt gaaaaatgaa atttgatctt gatgaataga taaaaaaaac cgttcagatc
     1561 tgaaaataat ctgagcggtt ttttgagtaa aaatagttta tgattattct taattaaaca
     1621 tctatttatt tttaaagctt tcatttatcg ataagaatag tttaactgtt gatttattcc
     1681 attttccgtt catctggtac gatgccttga cttagcaacc acttgtggaa gaaccattct
     1741 gccacaccga tcaatagagc aggaatcaat actttcatcc aaatatcgac tgtatcattc
     1801 ataaaatata gatagagcca caagataact gcagctgaac cagcatctgc gatcgtcgct
     1861 gcgatgttcc ctactttacg taagatcaac agatccccta gcacatagat catgactaca
     1921 ataattaccc caacaatcgt tgaatccata aagctaacac cgtataaacc tgtcagcacg
     1981 acccacagaa tcgcccagat catgattgcc ttcactacca acgccttcac atgtttcatt
     2041 ttctgcactc ctttctcctg gataaaaaag taagattatc taacaagata accttttcat
     2101 tattatacca tcggctgaga gaagcgagca aagataaggt cctatctaaa aatgaggaag
     2161 ccacttagaa cattcacgta ataatttatc cgtacagaca ttcgatatgg tgttccttta
     2221 ctttcgcata ctgttctttt gtcagttctt tacttgtcac cagataatcg atttcatgaa
     2281 aagcaatggc ttgatgcatg aatttatgtg caattttttg ctgtgtaact aaaacggcaa
     2341 gccggtctga ttgttttcta aaagcttttt tgaccattgc ctctccttca tgagtttctg
     2401 ttactccttg gctgaaatct agcccgcgac aactcattat cgctaaatcc gcataatatg
     2461 acaatgcatc gttataggct tttgaaccgt tgattgttgc tcgtttcgga acaattgccc
     2521 ctcccaatac agatactttt gccgttgtat attcactcaa catagcagct gtgacgatgc
     2581 cattcgtaat gatctgcaaa ccatcaaatc ttgctaggtt tctgactaag tgtaaagagg
     2641 ttgtactgga atccaagaat aagaccatat catctcgaat caaagaagaa gctgtatctg
     2701 caatcttacg tttttctgtt tcttcttcta atttggtgat cttcatcagg taaggcacgt
     2761 caatttttcg attgtcaata agcatggcgc caccgcgaac tctacggatc aatccacttt
     2821 tttccagaaa aacaaggtca cgtttaatcg tggcttcgct ataatttact aactcgatca
     2881 aatcggtgac tcttgcaaat tggttgtttt ttagataatt cacaatctcc tgctgtctat
     2941 tctccacttc attcaacata aaatcacccc atttacttta tatagtaaca ggaaaaaaga
     3001 ggttgtgaca gaagtgattg gcttcgagaa ataagaagaa atttttcgaa aaaactactt
     3061 ctgaacatcg tgtgtggtta agagggtatg acaagactat tgtcataccc tcttgaccac
     3121 acatttttat ttttagtata aactagcctt gcctactgtg ttcaaaattt ccattttatg
     3181 tttgaccact tcttgtacct ttttattagc tgctggataa attgcattcg gctcgtacat
     3241 cgatggattt tcactcaata tttctctcaa agcattgaaa aagacgcttt taagatctga
     3301 gctcaaattc actttggcaa ctccgtattt tactgcttcg ctgacttctg cgtccggatt
     3361 acctgaaccg ccatgtaaaa caaatggaag atcgatttgt tggttcaatt ctttcagtaa
     3421 gtcgatattt aattttggag ttctgttttt cggatacaag ccatgcgctg ttccaattgc
     3481 tacagcaagt gtatcgattc ctgtttcttt cacaaaaatc ttcgcttgat caggatctgt
     3541 ataaatgatt gtttcagcac ctccttcagc agaaccatta ttcccaatcg ttccaagctc
     3601 agcctccact gagacattta ccgcatgagc taacgcaacc acttttttcg taatctgtac
     3661 attgtcgtcg aatgatttca aagacgcatc gatcatcacg gaagaatagc cgtttcgaat
     3721 cgcccgtaag acatcttcta tcgtaccgcc atgatccaag tggataacga tcggcagttt
     3781 acttgtataa gcataggctc ttactgccgc aacaaactca tcacttaaat aggcgatttc
     3841 atcaggatga atttctaaga ttactggtgc ttctaatctc tctgcttctt cgatgattgc
     3901 tttcatcata tcatagctgc aaatattgaa ggctggtact gcaaattgat tctctttagc
     3961 cactttcaat aactctttca ttgtatataa cattacgctt ccacctcatt tgttagattt
     4021 tcatttttcg tccacttgtc ttgttttttc tctttcactg tttttttcaa tagtccaagc
     4081 ataaaggctg tagtgactgt acctgatgca attgccaaga catacatagg taaattgttc
     4141 ataacatttg gaattagcat cacccaaatc cctccatgag gtgccattga agtaactcct
     4201 actgccatgg aaatccctgc agcgactgct gaacctgtca tcaaactagg tatcacgcgg
     4261 atcgggtcag ataccgcaaa cggtatagca ccttctgtaa tatacgaagc gcctaaaatc
     4321 cagcatgatt gacctgaagt ccgttcttct ttggtaaatt tatgtttgaa taataaagtg
     4381 gctaaagcaa tacctagggg aggtgtcatt cctgcagcca tacaagcagc aatcggtgca
     4441 tttactccag ctgacatcaa accgatcgag aaagtcgaag tcgatttatt gatcggccca
     4501 cccatatcag ctgccatcat gatcccgata agtaatccga acaatagccc ggatgtattt
     4561 cccaagctat tcagccaatt tgtcaaagca tccaacaccc atgtgatcgg ttgttcaatc
     4621 acaaatacca tcaaaagccc aataattaag atcgataaaa aggggacgac aatcagctga
     4681 taaatagcag aaaattcttt ttttacgcta attttatttg ccagaaaatc acagatatac
     4741 cctgctagca cgccaccaat cattccgcca agaaaacctg aaccacctgt agaggccagt
     4801 aatccggcaa caattcctgg ggcaaaacct gcttttccag caatcgatgt agcaatcccc
     4861 gcgcctaacg caggaaccat catggcaaac gctgtatctc ctccgatcct tgaaaatgca
     4921 gctgctaaca cattatagtc tgctgagttg ggatcagccg ctgtaatccc aaaggcaaaa
     4981 ctcagtgcga tgatgattcc gcctgcgatc acaaatggaa gcatgtaatt cacaccattc
     5041 atgaaatgat tatagattgt cggctttttc tcatttgcag ctggttcttt ttcattagac
     5101 acaacgaata cgccaatatc tctcaatgct tcgtctatta ctacttgcgg ttctttgatt
     5161 gctcggcttg tagagacacg ctttactttt ttcccggcaa atcggtccaa ttcgatttct
     5221 ttatctactg caagaatgat tgcatctgcc tctttgattt cttgttcaga taactgattt
     5281 tctgttttta caccttgtgt ttcgaatttt gcttgatggt ttagatttct tgctgttact
     5341 tctaattttt ctgccgacat ataagtatga gcaattccag tcgggcaagc agttacacca
     5401 acgattttca tgattatttt cctccttttt cttcactatc gatactcgga caaagactct
     5461 actattttca ttcttgacta atctgtctga tgatatctgc tggcgtagtg gcttctttta
     5521 ttccctttct aaaatctgca ttcatcaatc gtctggagag tgtgctgaga atctctagat
     5581 gcatatctgc tgatttttca ggaactacga tggcaaaaat atattcaatt ggcatttcat
     5641 ctatcccgct atagtccgtt aatttggctg tatgaaaaaa acacagtgct ggttttgtca
     5701 catatttgct ttttgcatgg ggaatcccaa atccatcttc tattcctgtg gagatctcct
     5761 cctctcgttt gaatagtgcc ttaacgactt tttgaacatt tcttacctta tttgtttttt
     5821 tcaacacatc ccctattcgc tcaaataatg atccttttga atctatcgat ggatcgaaaa
     5881 caatcagttc ttctgcgatc aattgatcaa acctcataaa aaacctctcc cccacaaaaa
     5941 atgttaacgt tttcttggaa ctgaggtcag tatagcatcg ctagctgtac cgttcaatat
     6001 tatgaatgaa cagaggaaaa agacccatca tccgcgtgta taagtcatta aaatgaacga
     6061 tctagctcac aaacaatcgc aagtctataa caaaacaaaa agccttcctt gaaaggaaag
     6121 cttagcttct aattttaggt aaatggtttt ttacttcgaa ataacccctc ttcatttcgt
     6181 taatataagg tgtttttatc aagtggataa ttaaaactat atactagttt ttcattgttt
     6241 tgtgcattat gatcctacga ctttttcagc atcaaacgaa gttttaaatt ggcaaaaaac
     6301 ataaaaaaac agactatccc tatcagatag tctgctaaac gttgagttat cagcgttttt
     6361 attattccgc agcgtttgcg tctttgagac cgtatttttt gttgaaacgg tccacacgtc
     6421 cgtctgcttg tgtgaatttt tgacgtccag tgtagaatgg atgtgagtca gaagttactt
     6481 cgacacggat gactgggtat gtattaccgt cttcccattc aactgtttct tgtgaagttt
     6541 ttgttgaacc tgacaagaat ttgaaaccag ttgttgaatc catgaatact actgggtggt
     6601 aatctggatg gatgttttct ttcatgattt tttcgctcct ttgccctgct ccatttgctg
     6661 aaccagagtt gatttgtcga tttacaacat taacatctta acatgtttca gtcaaggttg
     6721 caattatctt ttcagatttc tggtcggatt ttttttacca aaggagacat cttgaaattc
     6781 tttgaaaaat tgctgattgt tttttgtttt acgcaaaaag cggatcagtt gttccgtata
     6841 ttctaatgaa tctccagtca tattttttcg aagtttccaa atttcttcta attcttcact
     6901 tggcatcaat aattcttctt ttcgggtacc tgattttttg atatcgatgg ctgggaagat
     6961 ccgacgttca gataattcac gtgaaagttg taattctaga tttccagttc ctttgaattc
     7021 ttcatagatc acgtcatcca tacggcttcc tgtatcgact aaagcggtcg ctaaaatcgt
     7081 caaactgcca ccttcttcga tgtttcttgc tgccccgaaa aatttcttag gtttatacaa
     7141 tgcggctggg tcaatcccgc cactcaatgt acgtccgctt ggtggaacga ctaagttata
     7201 ggcccgagca agtctagtaa tactatccat caagataacg acatctcgtt tatcttcgac
     7261 taaacgcatt gcgcgttcca atactaattc agaaactcga gtatggtttt gcggctgcag
     7321 atcaaatgta gaagatacca cgtcgccttt cacgcttcgt tctagatccg ttacttcttc
     7381 cggtcgttca tcaatcagta gaacgattaa ttctacttcc ggatagtttt cggtgatacc
     7441 atttgcgatt tcttttaata cagaagtttt ccctgctttt ggcggtgcga cgatcaatcc
     7501 acgctgacca aaaccgattg gagaaaagat atcgatcatt cgggtagata gtctttgcgg
     7561 tgttgtttcc agttgaagct gtctttgcgg ataaagaggt gttaaggctg gaaaatgcgg
     7621 acgttctttt gcttcttccg gatcttttcc attaacgctt tccacgtgca tcaaaccata
     7681 ataacgttcc gattctttag gtggacgggc ttttcctgcc actttgtccc catttctcaa
     7741 actgaatcgt ctgatttgtg aggcagaaat atagatatct tctgcacttg gtccataatt
     7801 gattggccgt aaaaaaccgt aaccatcttg accaacgata tccaatattc cttccatata
     7861 ataaaatcct tgtttctctg cttgtgcacg aatcacagct agagataatt cctttttatt
     7921 catcttactg taataaggaa ttttaaattc tttggcataa ctataaactt cttttaacgt
     7981 tttgttctct agttctgcca ttgtcaaata atcgctcatt cagctcccac ttcctctatc
     8041 atttcaattg atgcccctaa ggctgttagt ttctcgataa tatgatcata accgcgtaag
     8101 atataatcta cattgtaaat cgtcgttgtc ccttctgcca atagtccagc aatcactaaa
     8161 caagcacctg cccgaagatc agaagccacg acttctgtgc cgtgaagttt atttggacca
     8221 ttcacgatga tcatatttcc ttccacggta atatcagcgc ccattcgtgc tagttccggc
     8281 acatggttca cacgtttcgc atagatcgta tcgatgattt ctgaagtgcc tgtagtcatc
     8341 aatagtaacg cagtaagtgg ctgctgcaga tctgtggcaa atcctggata aggataggtc
     8401 atgatgtttg cgggttttaa ttctttcgag gggtaaactt cgatttcatc ttcgctgatt
     8461 ttcatatgga caccaatttc ctgcaatttt gctataaagc tttccaaatg ttcaaagatc
     8521 acatttttca ctttgatacc atttcctact gcagctgcta atgctagata ggttcctgct
     8581 tcgatgcggt caggaatcat gaaatgccga cagccatgta atgtttcgac tccttcgata
     8641 cggatcacat ctgtacccgc tcctcgaact tttgccccca tattattcag taaagttgcc
     8701 acatctatga tttccggttc tcgtgcagcg ttttcaatta ctgtctgtcc ttttgctttt
     8761 acagcagcta acatcacatt gatcgttgct ccgactgaaa ccacgtccat gaaaatccga
     8821 ttgccacgca atcctttatt ttctgtccgt aaatacatgg caccatgttc atttgtcact
     8881 tcagcaccta gagcttcaaa tcctttgacg tgtaggtcaa tcggtctagg gcctaaataa
     8941 cagccacctg gcaggcctac taccgcttcg ccaaatttac caagcagtgt tcccataaaa
     9001 taataagaag cacgcaaact attgattttt ccgtgcggca tcggaatcga tacgacttct
     9061 cgaggatcga tttctagtat gttgttggaa aaatggacag ttgcgcccat gatctctaaa
     9121 atttcaatta atgaatgaac atcttgtatg tccggcacac cttccaagat cactggggaa
     9181 tcagctaaga ttgcagctgg aatcaatgcg actgcactat tttttgcacc gctgatcgtt
     9241 acttcaccag ctaaaggtcg gtttcctttg attacgattt ttttcatctg tttccacctt
     9301 gtttattaat cttttttcat ggatatgctt gtattttatc atagataaaa aaaagaaacg
     9361 agcatggtct gccgttttaa gtaaaaaaga atggagagcg acttcaaaag tcgttctcca
     9421 ttcctatata tcgtatctgt tatgtggatg cttacgcttt gttagctgaa ccgaaccagt
     9481 cgatatgaga tttagcatct tcaacgattg ctgctttacc tggagctaat aatttacgag
     9541 ggtcgaatcc tttaccttct ttatctttac cagcttcgat atatttacga gtagctgcag
     9601 caaatgataa ttggaattca gtgttaacat ttacttttga gatacccatt gagatagctt
     9661 tttcgatttg atcttgagga atacctgatc cgccatgtaa tactaaaggc atgtctggac
     9721 ctacagcatc agcaattgct tgtaagtggt caaaagctaa tcctttccag ttttctggat
     9781 attgaccatg gatgttaccg ataccgcaag ctaagtagtc gatacctgta gcaaccattt
     9841 gtttgcattc ttcaatatca gctaattcgc cgttaccgat gattccgtct tcttctccgc
     9901 cgattgaacc aacttcacat tcaactgaga taccttttgc atgtgctttt tcaacaacgt
     9961 ctttagctaa tttcaagttt tcttcaaatg gtagatgtga accatcgaac attactgaag
    10021 tatagcctaa ttcgatacat tccaaagcag cttcgtaatc accatggtct aagtggatag
    10081 caactggaac agtgatgttc attgcttcaa ctaaatcagt gattaaatct ttacagattt
    10141 tgtaaccacc catgtattta gctgcaccca ttgatgtttg gataagtact ggtgcttgtt
    10201 ttgcttcagc cgcttcaagg attgcttgag tccattccaa gttgtttgtg ttgaatccgc
    10261 cgacagcgta accgccttta cgagcagctt ttaaaaattc agctcctgat actactggca
    10321 taataaaatt cctcctaagt tttgtaaaac taaatttgtt aagacaattc ttaaccaacg
    10381 accctatttt accaaacatt tcggtagttt tctactaaaa tcaatgaaaa tgaaaatttt
    10441 caagaagttt tttgcaaaaa ataaaatatc caatagcgct ttaatcgaaa aaagtctttt
    10501 gctttctatc ttttttccta caaataataa caaatcagaa aaagagaaaa gtgacaagaa
    10561 aattgcttat ccccttctct tgctactttt ctctttctat caagttcaaa aattattttg
    10621 tttcgtgatc tgctaatgat gctccgacaa atgctttgat taatttttgc gggcgatttg
    10681 gacgagaaat caattctggg tggaattggc atcccacaaa gaattttttc tctggcagct
    10741 ctacgatttc tactaaacgg ttatctggtg agacacctga aaagactagc ccttgttctt
    10801 caaacaattg acgatatttg ttattgaact catagcggtg acggtgacgt tcttgcacaa
    10861 catcggctcc atcatatgct tcagccgtct tcgttccttt tttgatttta catgggtata
    10921 atccaaggcg taaagttcca cccaaattct cgatgttttc ctgatcagcc attaaatcaa
    10981 taatattgtt tgctgtatct ggattcgttt cagctgatga cgcatcttct aatccaacga
    11041 cgttacgtgc aaattcgaca caagccatct gcataccaag acaaatacct aaaaacggaa
    11101 cgtcattttc gcgagcataa cgaatcgctt cgattttccc ttctactccg cgatcaccaa
    11161 atccaccagg aaccaagatt ccatctgcgt ctttcaaacg ttcttctaca ttttctctcg
    11221 ttaattcttg tgctttgatc caatcgatct cgatgtctga attataggcg aaaccagaat
    11281 gtttcaatgc ttcaactact gagatatatg catctggtaa ctcgacatat ttaccgacaa
    11341 gcgcaatccg tacttttttc ttcaagttca agacacgttc ttctaattct ttccattctg
    11401 tcatgtctgc ttctggtgta tctagtttta aatggtcgca aacaatttga tccattcctt
    11461 gtgcttgtaa aactaatggg atggagtaaa gtgtatctac atctggcgac tcgataactg
    11521 cttctggttc gacatcacaa aattgtgcca atttgttttt cacgctttga gaaacaggtt
    11581 gctctgtacg taccaccaaa atattcggtt ggatacctaa accacgtagc tcttttacac
    11641 tgtgctgcgt tggtttagtt ttcatttctc cagcagcttt caagtaagga atcaatgttg
    11701 tatggatata cataacatta tctgtaccga catctgcttt catttgacga agtgcttcaa
    11761 ggaatggcaa agattctata tcccctactg ttccccctac ttctgtaatg atcacatctg
    11821 aatcagtcat tttagctgct cgcatgattt tttctttgat ctcatttgta atatgaggaa
    11881 taacttgaac agttgctccc aagtattcgc ccttacgttc tttacgcaaa acttcagaat
    11941 agatttttcc tgtcgtcacg ttggagtatt tgttcaaatt gatgtcaata aaacgttcgt
    12001 agtggcccag atccaaatct gtttcagcac catcatctgt tacgaatact tctccgtgct
    12061 gatatgggct catcgtcccc ggatccacgt tgatgtatgg atcaaatttt tggatagtta
    12121 cttttaagcc gcggtttttc aataagcgtc ctaaagaagc tgcaacaatc ccttttccga
    12181 ttgatgaaac gacaccgccg gtcacaaaaa tatattttgt cataagttca aaaactcctt
    12241 tttaatttat gtgcaggaaa agtctcagac aataaacaaa gctccctatt cttcaataag
    12301 aatagggagc cgaaatttct gtaaacttct gaccctctaa aagggtgccc aaggtgtata
    12361 atacaagctg actaagggaa agtcaagtac tcaaatgaat actatccgct tacaattttt
    12421 tctttttcga tatcctttga gaaattattt cttaagtcct ttatgagtgc aaaaaaaatt
    12481 taacccacat aataagcttg atataaacat agctaacgtt aaacctaagc aaatcagaaa
    12541 atcgttactg aaaaatttta agtgaaataa tagataaaaa aataaaacaa acattatgat
    12601 agataatatc ccacctaaca aagaactact ttttcctact tgcagcaaca gtttatatag
    12661 cttatcgtag aaacaatctt tttctttcac ccttatttac ctcctttacg taaaaaacgt
    12721 agtccacagt tctcggattt ttggcatatc ttttctatta aataatatca aaaacaaaac
    12781 aattccacta attttttcaa agatgacctt tttttcaaca aaagtgcctt gtagggattc
    12841 attgaaggta acgaatcaca taagtaaaaa ataaggagat gcgacaaaag tcgtgcctcc
    12901 ttatttctaa ataaacggtg ttctcctgcc aactcctcgg tcacaagtca caatatccat
    12961 caaacatgag aagctgtttt tgaaattatt tcttgtgatt cggagttaaa tggtaggctc
    13021 acaacctctg gataaacggt attcaaaagc cagtttctcg gtattaagcc aaatttatgc
    13081 aaaaatgtag aaagccattt tcacaaaatt tttcttaata ctcgaaacta aacgtctttt
    13141 tcaaaacctc ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa gttcagccaa
    13201 ttcaaaaaca agaaaagctg tttttgcttg gctattctta ttacttgttg cagggcagct
    13261 ttttcacaac ctctccacta aacggtgttc aatcagctga ccctcggtat tagctcaaaa
    13321 aacggcaaaa tatgaggaac tatttttccg ttagtttctc taatactcag gtcaaaacgc
    13381 tgatttcaca gcctctaatt cacggtattc ctgttttaat aaagttctag atattgttct
    13441 ctttcccact cggaaacagt ttgtctgaat gccgcccatt cgagacgttt tgcttcaaca
    13501 aaatttgaga agatatgttg tcctaatgcg tcaatcatta cattatcctt acgcaattct
    13561 ttgatagcat tatggatagt tgaaggtaag tcctggatat gtgcagcttc tctttcttcc
    13621 tcatccatta cataaatgtt acggtcaaca gctgctggcg gtgtgatctg attacggata
    13681 ccgtctagtc ctgcttgcaa caatactgcc attgccaagt atgggtttgc agatggatca
    13741 actgaccgca attccaaacg tgtggataaa ccgcgagatt ctggtacacg tactaatggc
    13801 gaacgattac ggccactcca tgcgacataa acaggcgctt cataacctgg aacgagacgt
    13861 ttataagaat tgactgttgg attgcaaacg gctgtgtagg cacgagcatg tttcagcaaa
    13921 ccacctaaga aatgataagc tgtttcactt agttccaatt caccgtcttt atcatagaaa
    13981 acatttcctt catcattgaa caaagacata ttgcaatgca taccagaacc attgatccca
    14041 aataacggtt tcggcatgaa agtcgcgtga agtccatgct tgcgtgcaat cgttttgaca
    14101 acgagcttga aggtttggat attatcacaa gcatctacca catctgcata tttaaagtca
    14161 atttcatgct gtcctggcgc tacttcatga tgtgaagctt ccacttcaaa gcctagactt
    14221 tctaattcca acacgatgtc acggcggcaa ttttcaccta aatctgttgg tgcaaaatca
    14281 aaataaccac ctttatcatt caaggtcgtt gtgatcccac cgtcttcgtc taatttaaat
    14341 aagaagaatt ctggttcagg tcctaaattg aaagaggtaa aaccaaggtc gcgcatatct
    14401 ttcaatgctc gtttcaaatt cccgcgagga tcgccggcaa atggtgtccc atccggatta
    14461 tagatatcac aaattaaacg agcaactttt ccatgagcac tttcccacgg gaagatcatc
    14521 caagtggaga gatctggata caaatacata tcgctttctt caattcgaac aaatccttca
    14581 atcgaagaac cgtcaaacat cattttattt tctaatactt tgtcgatctg gctcactgga
    14641 acttctacat ttttgatcgt acctaagatg tctgtgaaca tcaatcgtaa aaatcgtacg
    14701 ttttcttcct caatgattcg tttgatttct tcacctgtta tctgtttctt taccatggta
    14761 tccctcttcc ttttttaatt tattcagtca aagaattgtc tttgcaatcc ttgcgactga
    14821 taatgacctg ttttgcttaa cccaccttgc gccaaaatct catcacgaaa aatttgtcga
    14881 acgtcatgat ctgtcaacgg cttcttgttt tttgcttctt gttttttcgc ctgtgccatt
    14941 tcgtatacac gtttgatccc agccatattc aatccctctg aaagatagtc tttaatctca
    15001 agcaacatat caatatcatt cagcgaatac atacgtcggt ttccttcgct tcgttccgga
    15061 tgaactaaat cttgttcttc ataatagcga atttgccgag cagacaaatc agtcagcttc
    15121 ataactgtac caattggaaa tacggacata gatcggcgca attccttttc tcccatcaga
    15181 cgtccccttt cgttttataa gttggctaaa gtgtaccaat taaaaaaaat attgtcaact
    15241 gcatatgtta ggttttctaa catgagatct ctatttttta taaaataaca aaaaaataag
    15301 aacacaaaaa aggtatctag ttgattttcg taccagatac cttttatttt ttattatact
    15361 gtactatcct ttattagtgt ttttatt
//
LOCUS       DAZAOD010000061        15218 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000061 DAZAOD010000000
VERSION     DAZAOD010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.062"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(93..1136)
                     /locus_tag="ACHDPO_001912"
     CDS             complement(93..1136)
                     /locus_tag="ACHDPO_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFN3369527.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1513..2478)
                     /locus_tag="ACHDPO_001913"
     CDS             complement(1513..2478)
                     /locus_tag="ACHDPO_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFN3369528.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            2712..3557
                     /locus_tag="ACHDPO_001914"
     CDS             2712..3557
                     /locus_tag="ACHDPO_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFN3369529.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            3748..4935
                     /locus_tag="ACHDPO_001915"
     CDS             3748..4935
                     /locus_tag="ACHDPO_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFN3369530.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            4941..5297
                     /locus_tag="ACHDPO_001916"
     CDS             4941..5297
                     /locus_tag="ACHDPO_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFN3369531.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            5299..5637
                     /locus_tag="ACHDPO_001917"
     CDS             5299..5637
                     /locus_tag="ACHDPO_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFN3369532.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    5713..5969
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6032..7066
                     /locus_tag="ACHDPO_001918"
     CDS             6032..7066
                     /locus_tag="ACHDPO_001918"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFN3369533.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            7059..7745
                     /locus_tag="ACHDPO_001919"
     CDS             7059..7745
                     /locus_tag="ACHDPO_001919"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFN3369534.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            7769..8617
                     /locus_tag="ACHDPO_001920"
     CDS             7769..8617
                     /locus_tag="ACHDPO_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFN3369535.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEEKPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            8814..9587
                     /gene="sufC"
                     /locus_tag="ACHDPO_001921"
     CDS             8814..9587
                     /gene="sufC"
                     /locus_tag="ACHDPO_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFN3369536.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            9600..10886
                     /gene="sufD"
                     /locus_tag="ACHDPO_001922"
     CDS             9600..10886
                     /gene="sufD"
                     /locus_tag="ACHDPO_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFN3369537.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            10883..12118
                     /locus_tag="ACHDPO_001923"
     CDS             10883..12118
                     /locus_tag="ACHDPO_001923"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFN3369538.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            12105..12575
                     /gene="sufU"
                     /locus_tag="ACHDPO_001924"
     CDS             12105..12575
                     /gene="sufU"
                     /locus_tag="ACHDPO_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFN3369539.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            12580..13971
                     /gene="sufB"
                     /locus_tag="ACHDPO_001925"
     CDS             12580..13971
                     /gene="sufB"
                     /locus_tag="ACHDPO_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFN3369540.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14069..15211)
                     /locus_tag="ACHDPO_001926"
     CDS             complement(14069..15211)
                     /locus_tag="ACHDPO_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3369541.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
BASE COUNT         4975 a         2839 c         3252 g         4152 t
ORIGIN      
        1 gttgttgtta gaaggatatc tgcaaaatta aaaacagttg tgattcggac attgttccat
       61 gcgagaatca caactgtttt ttcatgttca ttctaaactt tgatcagcca aataaatagt
      121 aaagccatca ctgtttggag aagcccgaca gctaatccat aagataagaa gcgtgtacct
      181 tctttcatga attttgcaaa gtctaaacgc agaccaattg ccgctaaagc agtgatctca
      241 aaccagctgc tgataaaatg tgccgattgg tcaataacta caggtaaaga aaacaagctg
      301 ttgaccaaac aaaagatcac aaaccctaat acataccaag gaagcggtaa ttttcgtttt
      361 ttctgcgtat cagttggcgt ttcaaacaga gctggttgtt tcttgtgcat gaatttttca
      421 aacagataga caacaacaac gagcatcata atacgtagaa tcttaaatag catggcgaat
      481 tcgacaacag aattgtcaag taagcttgcc ccagcgacta cttgaccaac agattggagt
      541 gtaccaccca aaagtgcact tttttcaatg agatttccac caaacaactg taatccaaga
      601 aaagggagag tcaacatcat cacagtaccc agtagattga ctagtgtgat gatctgtcct
      661 ttttcttcct ctttcgcatg gatggaaggg gcgattgaag caatagcaga agaaccacaa
      721 acagcgtttc ctccagccat catcaaagaa gaagtatcgc tgaattgcag ttttttacca
      781 atcaagtaag caccgatgat agtgactgac atttgcagta acacaaaaac aattcctttt
      841 acaccaattt gagcaatcgt ttgagctgtg acagttgcac ctagtaaaaa aacagagaat
      901 tctaatagtt tgctttcagc aaattttgtg ccgattgcta gaacaggctg tttaaaaaaa
      961 gtatttccta ataaaatacc caataaaata gcaatagtcg ctccacctaa ctgtggcaga
     1021 taaatagcaa gaagcctgct gaaggcagcg atggcaaaag aaagcagtaa accgggtaag
     1081 atttcgcgga ccgctgaatc ctttacagat tttattggat gtgacaatga tttcatttga
     1141 tcggttcctt tcgtcaataa atactaaaag catactcgaa catagtagca ctaaaccagt
     1201 attttgacaa aagaacaaga ggtcgtgaca aaagtcttgt acgacctctt gtttcgaata
     1261 aacggtgttc cagaagtagc ttctacggaa ataagccgaa atttcacaaa aatttgagaa
     1321 gcaattttcg taaattcctt cttatttctt gaagctgacc acttctttta cgacctcttg
     1381 gtaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccagtac aaaaacatga
     1441 acagctgttt ttgtttggcc gttcttatta cttgatgcag aacagctttt tcacaaccta
     1501 ttgaatcgat tattaagcga tttttttaga aacaaatttt ccatgtttgc tatgttcttt
     1561 aattaagaaa cgtacgtaat gagcaagaac gtagaagaca actacacttg caaacagaca
     1621 ttccgcaact tttaagaaat ccaatacgct actatagata cctaaactgt tgaagtaatg
     1681 aacagtagta aatatagctg ttgcagagat aacaagcggg aatgtaaagg ctgcatagct
     1741 tggataaaaa cgaagcttga acaaacgtgg aagcatagac agcacaacga aatacaatac
     1801 ttgagataaa gcgaacaatg ctacgacaag ataaaaatta ggttcagcaa agtttttaag
     1861 ataacctgtt aggcaaagag aaccaggtgc tgcaacgatc gtaatcagcg gacgtgtcgg
     1921 atgagccata tttcttacga aaaagacacg tttgatgatg atcggcaata agaacgcata
     1981 gcagatcaat gaaatccaaa agaaaatttt tccaataagt gggaagaagt tcccggcagt
     2041 tacagtgatg accccaaatc caacgtaaat gataaaccag cttggataaa ttgcttcaat
     2101 tgaaagatca gctttgataa catggtgata attgaaataa aagacaagga tcacttggaa
     2161 gataacagcg cacagccaaa tgaatttgac aattggtgca atactttcat atgaaacaaa
     2221 ataagtacaa ataaccatga gtgacatcgt aaaagttggt gaaacggagg cgatgattgg
     2281 atcatgcaac gtttgtttcg tgtgttcgaa taagataaac aatttaacaa aaatgaatat
     2341 cataagaatc atagagatac cgccagttag attgcctaaa gcaacatggt gatagtcttt
     2401 aaacagattt ccaagggaag ctaacccaag gatcaacccg cagatcggga tcggaataat
     2461 tttcaaaaag ttcttcatat ataatattct cctttttatt taatagattt tagtaccaag
     2521 atgaacgaat acattgtaaa atgaatagga atgtatgatt acgagcaagc agacagctga
     2581 ttgtcttcat ctaagttact agttggatca gcaactgttt tgttgtacat ttctattata
     2641 gatggttttt tgtatattta aatcaaatag tttttatagt aattatcata aaaagttatg
     2701 gaagtggtgc catgtttaag ttattaacga cttttcgagc agtatatgaa acaagaaatt
     2761 tttccagagc agcagaagta ctgtttttat ctcaaccagc agtctcgaat caaatcaaac
     2821 agttggagcg ggaattgaat atcgatcttt ttcaacgtaa cggaagaaaa gagatgcttc
     2881 caactaagca agccgactta ttatatgaac ggacactggt tttgttagaa gaatgggaag
     2941 aaactcagca aaaattgctc aatgaacaaa atgaagaaga agtatgtcgg atcgttgctt
     3001 cccacacctt tgctgtctat cttttgcctc agttgatgaa acatctgatc aaaaggtttc
     3061 ctaaagtgca ttttgagatc gaaatcacga attctcatga atcattagaa caagtagcga
     3121 aacatgaatc cgattttggt tttatcgaaa agccattaga gacttccggc gtacaaagat
     3181 actctttgat ggaagaccag ctagtcatcg ctggggaccc aaaaagcaaa ttgtggcttg
     3241 taagagaagc aaactctggt gtttttcatt acacgcagcg ttattttgaa gagatgaata
     3301 tccaagataa gaagatgatc gtgaaaagta acgatgtaat tgttgcgttg ctgaaggaag
     3361 gaatcggtcg ctcgattttg tctaagcgct ctgttccaga aaatgtgcca atgactccgt
     3421 tgaatttcca tcgatatttt tatttcatcc aacgaaccaa tctggtttct gatcagctgc
     3481 tagagattgc cgaagagatc cttcgataca atgaaagcac agaaacttct cacagcgagg
     3541 agaatctcag ctggtagata attgcatgta tcaaaaaaag ttctatgata cactaaagat
     3601 aagcagtagg cttttgtact gcatttgctc aagcaactgc acaaacggaa agttaatttt
     3661 tcccaaatgt ctatggaaag actttccatt atctaactgg gccgctataa taatcagcag
     3721 tatggttttt aagaaaaggg atgaaacatg gaaaaaaaat taaaagcttc gaacgataat
     3781 cgtattgatt atggcgtgat tttaccagtc tttctgttat gtttgattgg tctgctctca
     3841 ttatatgtag cacttagcca tgatccgaac aatccagcag tcttgaaagg cgtagggatg
     3901 caagttgtct ggtatttagt tggagcggca gcaatcgttg tcatcatgca tttgaattcc
     3961 aaatggatct ggaaactgac tccttacctt tatggtttgg ggttagtggt aatgggactc
     4021 ttgctcaaat tctatgatca gaatttagct gcttcaacag ggtctaaaaa ctggtttcga
     4081 ttcggtgcgt ttactttcca gccagcagag ttgatgaaga ttgcgtacat cttgatgatg
     4141 gcactgatcg taactaaaca taatacgcaa gtaaaagaac ggacgatgaa atcggacttt
     4201 tggctgattg ggaagctctt gatcgtgaca ataccggttt tagcattgat catggcccaa
     4261 gatgactttg gaacgatgct tgtctttctt gcgatctttg gcgggatttt cctgatgtct
     4321 ggaatctctt ggcgcatcat cgcacctgta gtaatcttgg cagtagtcgt tggagcagga
     4381 acgatcttct tggttacgac tgaaggcgga agagacttgc tttataaagt tggattcaaa
     4441 tcttatcagt ttgcacgtat tgattcatgg ctggaccctt tccatgatac gtcaggaatg
     4501 agttatcagc cggcccaagg acttttggca attggtaccg gtggcttgtt tggtaaagga
     4561 ttcaacgtaa gcaatatcta tgtgcctgtt cgtgagtccg atatgatttt taccgttatc
     4621 ggtgaaaact tcggctttat cggtggtgca ttcgtcattt tcttgtattt tattttaatc
     4681 tatcgtatga ttcgggtgtg tttcgatacg aataatgaat tttacgccta tatcgcaagc
     4741 ggtttgatca tgatgctgct gttccatgtc tttgagaata ttggagcaaa tatcggatta
     4801 cttcctttaa cagggatccc attgcctttc attagtcagg gaggatcctc gattttaggg
     4861 aacatgatcg gtatcgggtt gatattatcg atgagatacc aaaatgaagc acctgcaaga
     4921 tcttcaagga ggtaagaaaa ttgtacacct tttactggta cccgaaatgt tcaacatgca
     4981 aaaaagccaa agcgtggtta gaccagcatg gcgttagtta tcaaaccgtt gatatgatca
     5041 aagaagtacc gaaggcctca acgattgaga cttggctaga aacgagtcaa gtaccaatcc
     5101 gtcgcctgtt caacacaagc gggatgaaat atcgggaact tggactgaaa gatcaagtag
     5161 gcgagtttac ggcttcaaaa gcgagccaag tcttatcgac agatggtatg ctgatcaagc
     5221 gaccactgat cttacgagag gaccagcttg ttgcaattgg attcaatgaa aaaatttatg
     5281 aaggagaact gatataaaat ggcaggcaag catttgaaga aaaaggacaa cctttggatc
     5341 ttatttaatg gaaaagaata ctgtgttggt ttgacaaatg aagcgcaaga agaacttgga
     5401 gacatcacgt ttgccaatct gccaaaagca ggacaatcgc taaaaaaaga tgaacctctg
     5461 atcgaagttg aagcggaaaa agcggtcaat gaatttgcca gcccgctaac gggtacagtt
     5521 tcttctgtta atgataaaat cggtgaagat atcaatatct tgaatgattc agatgaaatg
     5581 aatgcgtgga tcttaagttt caaagatgtt gatccaaaag aatttgacga attataaaat
     5641 cagaaaatca cttgaaaaaa gttgacactg attcttccag ttgctataat cataagcaat
     5701 cctatatgaa acgagaaagc tttgaaaaga agagtacatg tcacggacgt ttgaagagag
     5761 ccctgtttgc tgaaaatggg taacgaaaat gagatggaag atggtcttag agcagagtaa
     5821 gcgagcgtaa gcaaacttac tacgggagtg cccgttacag cgcgacagta tacggaaaga
     5881 agctaagtcc aagtactgga agaggctgtt attgcgaagt aacggtaaat caaggtggta
     5941 acacggaagt tcaagctttc gtccttttgc ttaaggcaag agggcgaagg cttttttgtt
     6001 tgaaaaatta taagagaaag atgtgaatgg catgtcatta atccaactaa cgaatgtcaa
     6061 aaagacattc aatgggaaaa acggaaacat ccaagccgtc aatgacgttt cactaaacgt
     6121 tgaaaaaggg gatatttatg gaatcgtcgg ctattctggc gcaggaaaaa gtacattagt
     6181 ccgtctcctg aatggacttg agcttcccac gagcggcgaa gtgatcgtaa acgatcaaga
     6241 tattacaaaa ttaaaaaaca aagaattacg tacattccga aagaaaatcg gtatgatctt
     6301 ccagcatttc aacctgttat ggtcaagaac tgtacttgaa aatatccagc tgccgctgga
     6361 attagctggc gtaccaaaga gcaaacgtaa agaacgggca gaagaactgt tgcgtttagt
     6421 cgggttagaa ggacgcggac aagcatatcc ttcacaactt tccggcggac agaaacaacg
     6481 cgtcggtatc gcacgagcat tggcaaatga tcctgagatc ctgctttgtg atgaggctac
     6541 tagcgcattg gacccgcaaa caacagaaga agtattagac ttattgttag cgatcaataa
     6601 gaaattgaat ttgaccatcg tcttgatcac acatgaaatg aatgtgatcc gcaaaatctg
     6661 caacaaagtc gctgtgatgg agttggggaa agtcgtagaa gaaggagacg tattgactgt
     6721 cttcagacaa ccgaaaaaag aagtaaccaa acgctttgta caacaagaca tcgaaccaga
     6781 agctgattcg acagaactat tagctgaact catcaaagaa aatccaagcg gccgtttggc
     6841 aactttgacc tttagcgaaa gaaatgccaa cgagccagtc atttcccaag cgattcgacg
     6901 ctataacatc gatgtcaacg ttgtgtatgg aaagatcaaa caagtgaaag aaggttcctt
     6961 tggttcattg actgtcttga tgactggtga aaccaaagaa ttagatcaag cagaagtgtt
     7021 catcaaagaa caaggagtag gaattgaggt gatccatcgt ggataaaagc ttttcagaaa
     7081 catatctaga ttttaaacaa atcaacccgg aaacgatgaa tcaggctatc cttgatacac
     7141 tatatatgac attaatctca atggtcttag tgacgatcat cggattagtt ttgggattga
     7201 tcctttactc tattggacgc aaaaacaaac cgtatgctcg aatcatttat ggaatcgtat
     7261 cgatcatcag taatattttc cggtcaacgc catttatgat cctgatggtt ttgatcattc
     7321 catttactaa agcaatcgta ggcactatgc taggtgcgca agcagccatt ccagctcttg
     7381 ttttatccgc agcaccattt tatgcccgtc tagtagagat tgcttttcgt gaagtcagcc
     7441 ctggtgtact ggaagcagca gatgcaatgg gagcaagtta ctgggaaatc atctggaagg
     7501 tcttgatacc tgaaagtatt cccgcattga tttctggatt aacagttaca acgatctcga
     7561 tgatcggatt tactgcgatg gccggcgcga tcggcgcagg tggacttgga ggtcttgctt
     7621 ggcaggaagg ctaccagcgt ggtaatctaa cagtgacatt cgttgcgact ttaattattt
     7681 tactaatcgt atttatcgtt caaggaatcg gtgatttctt aactaagaaa acagacaaaa
     7741 gataatagga tataggggga tgtaggatat gaaaaagaaa atttttggat ttgcagcagc
     7801 gcttttgctg actgtaggat tagcagcatg cggtaacaac agcgacagca aagattcagc
     7861 aaataaagca gacgacacga cattgaaagt cggcgcttca ccgacaccgc acgcagagat
     7921 tttggaacat gtgaaaccat tattgaaaga tgaaggaatc gatcttgaaa tcgtcaaatt
     7981 cgatgactat gtattaccga accaatcttt ggaagaaggc gacattgatg ccaattactt
     8041 ccagcatatt ccttatttga acaaagaaat caaagaaaaa ggatatgact ttgtcaatgc
     8101 cggtgctgtc cacatcgaac caatgggctt gtactctaaa aaagtcaaag atgtttccga
     8161 attaaaagat ggtgcaacaa tcattacttc aaattctgaa tcagactggg gacgcatcat
     8221 cacaattcta caagatgctg gcttagtcaa agtcaaagat ggagtagatc tggaaacagc
     8281 aacattcgat gatattgaag aaaaacctaa gaacttgaag ttcaaccata cgatcgaccc
     8341 atcactttta gcttctacgt accaaaatga tgaaggtgac ctagttgcaa tcaacgcaaa
     8401 cttcgcttac ggcgcagggt tgaatccatt agaagatgcc gtattgcttg aaaaggacaa
     8461 ctctccttac gtgaatatta ttgcgactcg taaaggtgat gaagacagtg acaaaatcaa
     8521 aaaactgatt gaagtgcttc accgcaaaga agtccaagaa tggatcacag acaaatgggg
     8581 cggctctgtt aaaccagtaa aggctgatgc aaaataaggt atggaacaaa aaagatgaga
     8641 aataagtctg taatggctta tttctcatct tttttatacc tattctaatt tagaaatcaa
     8701 aattgtttaa taataaataa aagatatttg attttagtaa ggaaggtcat tgcgcttcat
     8761 tctcaattag tctaaaatga gtgagaacga aagagaattt gggggtataa tgcatgtctg
     8821 tcttagaaat aaaaaatcta catgtgtcga tcgaggaaaa agaaatcctt aaaggcgtaa
     8881 acctaacaat gaaaaccgga gaaatccatg ccatcatggg acctaacggc acaggaaaat
     8941 ctaccttatc tgccgctatc atgggcaatc caaactatga agtaacagaa ggcgaaattt
     9001 tgtttgacgg gaaaaatgtt ttagacttgg aagtagatga acgtgcgcga cttggcttat
     9061 ttttagctat gcaatatcca agtgagatac caggtatcac gaatgcggaa ttcatgcgtg
     9121 cagcgatcaa tgcgaaacgt gatgaaaacg acaaaatttc tgttatggca tttttgaaaa
     9181 agttagatga aaaaatggct ttactaaata tgccagaaga aatggctgaa cgttatctga
     9241 acgaaggttt ttctggcgga gaaaagaaac ggaatgagat cctgcaattg ttgatgttag
     9301 aacctacatt tgcaatttta gacgaaatcg attcaggtct ggatatcgat gctttgaaag
     9361 tcgttgctaa aggagtaaat gaaatgcgcg gagacaattt cggtgcattg atcatcaccc
     9421 actatcaacg attattgaac tatatcacac ctgatgtcgt tcacatcatg atggaaggcc
     9481 gagtagtcat gacagggaat gctgacctag ctaaacgtct ggaagcagaa ggctacgctg
     9541 gtatcagtaa agaattagga atcgactata aagaagaaga agcgtaaggg ggagcaagaa
     9601 tgaaagaaaa aaactggctc gattatcttg acgcggtaaa tgatttttct ttaagtaaag
     9661 gcgaacctga ttggatgaga accttccgtc aagacgcact agcgaaagca gatgaactgc
     9721 cattgccgca tatcgatcgg gtgaaattcc atcgctggtc gttatttgat gtgaaagaaa
     9781 cacaaaccat cagtgaaaca ggcacgattc cggcatttga tgcaatgaaa gacaatcctg
     9841 tgcttgtcca acaaggttca tggacgattt ttgaacaact gcctgtggaa ttagcagaaa
     9901 aaggagtcat ttttaccgac ttgttcactg caatgatcga atatccagaa ctagtccaag
     9961 aatattatat gaaaaaagca gtaaacatga acgaagacca attgactgca ctccatgtag
    10021 cttttatgaa cagcggtatt ttcctgtatg tgcctaaaaa tgtcgtgatc gatgaaccac
    10081 tcgagtcctt attcattcaa gatggcgcat ccgatgagca cttcttcaag catgtgttga
    10141 tcgtggcaga tgaacatagt gaattttctt atctggaacg tttccagaca accaaagaac
    10201 aagtagcaaa atcatcaggt aatatcatcg tggaagtcat cgctaaagct ggttcaaaaa
    10261 tcaaatattc agccgtagat caattaggag aaaatattac ttcttatatg aatcgccgtg
    10321 ggcacatttt acgagatgct tctgtcgact gggcaattgg tgtcatgaat gacggtcatg
    10381 tgatcgctga ctttgactca gatttagcag gagaaggtgc acacgcagaa gtcaaaatcg
    10441 tggcaatcag ctcgggcaga caaatccaag gaatcgatac acgagtaacc aataaagccc
    10501 ctcatacgat cgggcatatt ttgcaacacg gagtgatccg agaaaaagga acattgacct
    10561 ttaatggtat cggccacatc ttgaaagggg caaaaggtgc agatgcccaa caagaaagtc
    10621 gtgtcttgat gctttctgat aaagcacgtg gtgatgcgaa tcctattctt ttgatcgatg
    10681 aaaacgaagt aactgctgga catgctgcca gtgtaggacg agttgatcca gaagaaatgt
    10741 actatctgat gagtagagga ttgcataaag aagaagcaga gcgcttagtg attcgaggat
    10801 tcctcggttc tgtcttaaca gcaatccctg tagaacaagt tcggaaagaa ttagtcgaag
    10861 taatcgaagg gaagttgaat ggatgatcga tgctaaaaag ctacgcaatg attttcctat
    10921 cttatttcaa gacgtcaatg atgaaccttt agtttatctg gataatgcag cgacgaccca
    10981 aaagccaaaa caagtactcc aggcattagc gtactattac gaacacgata acgccaatgt
    11041 tcatcgcggt gtccatacgt tagcagaacg cgcgacccat gattatgaac aagcaagaga
    11101 aaaagtacgg gcgttcatcc atgcaaaaga aacagcagaa gtgctgttta ctcgtggtac
    11161 gacgacaagc ttgaattggg tagccagaac cttcggcgac cgctatatca aagcaggaga
    11221 cgagatagtg ctctcttaca tggaacatca ttctaatgtt atcccgtggc agcagttggc
    11281 aaaacgaaca ggtgctgtct tgaaatatat cgaactaaca gaagaaggct tcctggatat
    11341 ggaggatgca gcgaaaaaga ttacggacaa aaccaaaatc gtctccattg ctcatgtatc
    11401 caatgtctta ggtgtcttca atcctgttca agaattagct gaacttgtcc atgaaaacgg
    11461 cggggtcatc gtagtagatg gtgctcaatc tgccccgcac atggccattg atgtccaagc
    11521 actagactgt gatttctttg ctttcagcgg acacaaaatg tgcggaccaa caggtattgg
    11581 tgttttatat ggtaaacgaa aatggttaga agaaatggaa cctgttgaat ttggtggcga
    11641 aatgatcgat tttgtcgaat tatacgacag tacatggaaa gaactacctt ggaaattcga
    11701 agcagggaca ccaaatatcg ccggcgctat cgcattaggc catgcaatcg attatttgca
    11761 aaaactcggt atggacaata tccatcgata tgaagaagaa ctagccgctt atgtgttgcc
    11821 aaaattacaa gcaattgatg gattgactgt ttatggtcca caagacccga attttcggac
    11881 aggagtcgtt gcattcaatt tggatgggtt acatccccat gatgtcgcga cagctttaga
    11941 catggaaggg gtagccgtca gagcaggtca tcattgtgcg caaccgctat tgaagtacct
    12001 tgaagtatca gcgactgctc gcgcgagctt ttatttctac aacacaacgc aagacgccga
    12061 ccgtttagtt gaagcaatca tggcaacaaa ggagtttttc caacatggga ctatctaaat
    12121 tagacaattt ataccgtcaa gtgatcttgg atcattcttc ccatccgcat catcgtggaa
    12181 gcttgactga ctcgacaagc aagatcgaat tgaacaaccc cacatgtgga gatgtgatcg
    12241 aattgcaagt cgatgtaaaa gacggaatca tcaaaaatat cgcctttgac ggcagtggct
    12301 gctccatcag tacggcaagt gcctcgatga tgacagacgc cgtcatcgga aaatcaatag
    12361 aagaagcaga acatttaact gtagactttc tacagcttgt ccaaggaaaa gaagtcaaag
    12421 atcccgacca attaggcgat gctgctatgc ttggtggtgt agctaaattt cccgctcgga
    12481 tcaaatgtgc gacacttgcc tggaaagcac taggaaaagc aatggaaaac gatggtaccg
    12541 cagctttcca tcattaccac aaggaagagg agtgagaaca tgggcgtacc agaattagaa
    12601 gaatataaat tcgggtttca cgatgatgtc gaaccggttt tcagtacagg agaaggcttg
    12661 acagaagaag tgatccgtga gatgtcaaga atcaaaggcg aaccagaatg gatgcttgaa
    12721 ttccgtctga aatctctaga aacatttaac aaaatgccaa tgcaaacatg gggccccgac
    12781 ctttcagaca tcgatttcga tgccatcaaa tattaccaaa aaccaagtga caaacccgct
    12841 cgtgactggg aagacgtacc agaaaaaatc aaagatacat ttgaaaagat tggtatacca
    12901 gaagctgaac gagcttatct agccggtgct tccgcacaat atgaatcaga agtcgtgtac
    12961 cataatatga aagatgaatt cgaaaagtta ggaatcgtct ttactgacac tgactctgct
    13021 ttgaaagaat accctgaatt attcaaagag tacttttcaa aacttgtacc gccaaccgac
    13081 aacaaattag cagcgctgaa ttcagccgta tggtcaggtg ggacctttat ttacgtgcca
    13141 aaaggcgtca aagtcgatgt tccattacaa acgtacttcc ggatcaatgc ggaaaacacg
    13201 gggcaattcg aacgtacgct gatcattgtt gacgaaggag caagcatcca ctatgtcgaa
    13261 ggttgtacgg cacctactta ttcaagtaac agcctgcatg ccgccatcgt agaaatcttt
    13321 acaagaaaag atgcgtattg ccgttacaca acgatccaaa actggtcaga caatgtgtac
    13381 aacttagtaa ccaaacgagc aaaagcatac gaaggcgcaa ccgttgaatg gatcgacgga
    13441 aacctaggtg caaaaacaac gatgaaatac ccaagtgttt acttagatgg aaaaggtgca
    13501 cgaggcacca tgctctccat cgcctttgca ggagcaaacc aaatccaaga tacgggtgca
    13561 aaaatgatcc acaatgcacc aaatacatct agctctatcg tctctaaatc aatttcaaaa
    13621 gacggcggag aagtaaacta tcgaggacaa gtaacctttg ccaaaaacag tgcgggttcg
    13681 atctctcata tcgaatgtga cacgatcatc atggacgaat ggtcgaaatc cgatacgatc
    13741 ccattcaatg agatccacaa cagccaagtc tctttagaac acgaagccaa agtctcaaaa
    13801 atctcagaag aacaactcta ctatctgatg agccgaggcc tgaccgaatc tgaagcaact
    13861 gaaatgatcg tcatgggctt tgttgaacca ttcaccaaag aacttccaat ggaatatgca
    13921 gtcgaactca atcgattgat cagttatgag atggaagggt ctgtaggtta ataactattt
    13981 cattgctcga aacgttgata ttaaagcgtt tcgagcgttt ttttatttgt attttaatgg
    14041 ttggctacgt ttttggctac gtttggaatt attcgcccat aaattttgca aatcggtcac
    14101 cagttttctt aacagattgt ggtgtgacat gagcatagat attcatggta gttttaatat
    14161 ctttatgacc taatcgttcc tgtacttctt ttatcgacgc accactttca aacaataagc
    14221 tacagtgggt atgcctaaat ccatgtggag taatttgagg ctccatcggt gtctttttgt
    14281 aaatccagtc taaccaatcg tttactactt gggggtagta caacttgttt gtgtttgtag
    14341 tgaaaagaaa ctgttttggt gaattcgtgt tatagccata taagatcatt attttcattt
    14401 gttcttgttg ccaaatacgc agttgtttaa gtgtaaaatc atcaagctga atcgttcttg
    14461 atgaattttt agttttaggt acttgtagaa ctacttgatt aaactcgtct tgagcgatag
    14521 ttttaccaat tgttattgtt ttattgaaat agtctatatc ttcccattga agcgccaatg
    14581 cttcgctttt acgcattcct gtataagcta ataaacggaa aaaagtgtac agtttaactg
    14641 aattattttc tttagtattc tgtaaaaaca gttgtaattg atctttcgtg taaaacttca
    14701 agggttgttc ttcttcaatt tttcttggaa gcaatgtttt agacatagga ttatccttac
    14761 agacttccat tgctactcca aatttaaata tttgagcagt tgtttttctc aagaaaccat
    14821 attgttttaa tgttttgtgc cattcattca cctgtttttg gcaatagcta acacttattt
    14881 tatccaatcg taattcccca aaagcaggta atatatggtt tttgcaaaaa cgttgagcaa
    14941 cggcaacaga agacggtttt actcttgttc tgtagttatc aatccataat tcatacaact
    15001 cttgaaaagt tgtaacattg attttaaact cttgtttttc tttaaagtct acaagtagtc
    15061 tattaagtgc tgtttgcgcc tcagcttttg atttgaatct tctacgcttt gtacgtatat
    15121 cttttccagt cttgggatct ttccctaaat aagtttcaaa tccccaatat ttttcgccat
    15181 tttgtaattt ataactaaaa aatgttgcca tttgattc
//
LOCUS       DAZAOD010000062        14907 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000062 DAZAOD010000000
VERSION     DAZAOD010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.063"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            163..1902
                     /gene="yfcC"
                     /locus_tag="ACHDPO_001927"
     CDS             163..1902
                     /gene="yfcC"
                     /locus_tag="ACHDPO_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFN3369542.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2059..3243
                     /gene="iadA"
                     /locus_tag="ACHDPO_001928"
     CDS             2059..3243
                     /gene="iadA"
                     /locus_tag="ACHDPO_001928"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFN3369543.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3354..3557
                     /locus_tag="ACHDPO_001929"
     CDS             3354..3557
                     /locus_tag="ACHDPO_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFN3369544.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3658..4320)
                     /locus_tag="ACHDPO_001930"
     CDS             complement(3658..4320)
                     /locus_tag="ACHDPO_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369545.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4333..5835)
                     /locus_tag="ACHDPO_001931"
     CDS             complement(4333..5835)
                     /locus_tag="ACHDPO_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369546.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6383..8062
                     /locus_tag="ACHDPO_001932"
     CDS             6383..8062
                     /locus_tag="ACHDPO_001932"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFN3369547.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8189..8668
                     /locus_tag="ACHDPO_001933"
     CDS             8189..8668
                     /locus_tag="ACHDPO_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFN3369548.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8887..9567
                     /locus_tag="ACHDPO_001934"
     CDS             8887..9567
                     /locus_tag="ACHDPO_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFN3369549.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9575..10906
                     /locus_tag="ACHDPO_001935"
     CDS             9575..10906
                     /locus_tag="ACHDPO_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFN3369550.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10921..11883
                     /locus_tag="ACHDPO_001936"
     CDS             10921..11883
                     /locus_tag="ACHDPO_001936"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFN3369551.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11994..12332
                     /locus_tag="ACHDPO_001937"
     CDS             11994..12332
                     /locus_tag="ACHDPO_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFN3369552.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12411..13118
                     /locus_tag="ACHDPO_001938"
     CDS             12411..13118
                     /locus_tag="ACHDPO_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFN3369553.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13221..14702)
                     /locus_tag="ACHDPO_001939"
     CDS             complement(13221..14702)
                     /locus_tag="ACHDPO_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3369554.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4739 a         2556 c         3188 g         4424 t
ORIGIN      
        1 aagagaaaaa aataatcata cataggagaa aaaaaacaaa atagaaaaaa gtgattttct
       61 aataaattat tcatgtggaa atgtcatttt tactgtataa ttcatttgat tatccatttt
      121 ttattcatca aaattactga aaaaagaaag gaagaaataa atttgaagaa aacaaattct
      181 tcaggaaaac cgaaacgcga cttcactaaa ttatcgacac cccatacgta tgtcattatt
      241 tttggtgtag tcatctttgc atggatactg acttttgtcg ttccagcagg aaagttcagc
      301 acgcaagata ttgaatacaa agatgcaaat ggcgaaacaa gtactcgtac tgttttacgt
      361 caagattcct tccgttatgc ttacgagctg gataagtcgt atgtgtttga tcaattagaa
      421 gaactgcaag atcatccagc agaacgtgaa aaactggatg ttccggaaaa aggattggaa
      481 aaagtcattg ctgacggaga aaaaaatctt acgcaggaaa aactagatga aatctccttg
      541 acagatgatg tgctttacga tcagtacggc gaaaatatct atgatacttc taaaaaattg
      601 cataaaacag ccaaaatatg gggaacagat gattttggcg gctttggttt cttaaatttt
      661 gtttttgaag gactagtatc tggagataag tatggatctg ctgtagggat cgctgcattg
      721 atccttgttg ttggaggtgc ttttggtatt attatgcgta ccggagcgat cgacgcaggt
      781 atctatgcgt ttatcagtaa aactaaggga ctggagcgtt tagctttacc gctattattc
      841 tttgcttttt cattcggtgg cgctacattc gggatggcag aagaggtaat tccattctca
      901 atggtgatgg ttccatttgt cattgcgtta ggatatgact cgatcgtagc agtaaccgtg
      961 acttatgtcg catctcaagt cggaaatgcg acctcttgga tgagcccgtt tagcgtagcg
     1021 gtggctcaag ggattgctgg aatccccgtg ttgtctggtg cgacattccg attgattatg
     1081 tgggtagttg ttactgcatt agccgctggt tatatgatga tatatgcaga aaaaatccgt
     1141 aaaaaaccag aaagttcgtt gacttacaaa tcagatgatt atttccgttc tcatatcaaa
     1201 aagacatctg atgaaaataa aaaattcatg cttgggcata aattgatctt attagagatg
     1261 ttagttgtcc ttgtctggat cgtttggggc gtgactcaaa aaggctatta cattccagaa
     1321 atcgcttctc aattctttgt gatgggatta gttgctggaa tcattgctgt tcttttcaaa
     1381 ttagatggaa tgaaagtcaa tgacatcgct tcttctttcc aatctggtgc agctgattta
     1441 gctggtacag caatcgtagt aggtatggcc aaagggattc ttcttgtctt gggaggatct
     1501 gatgcatctg ttccttcagc tttgaatacg attttgcatg ggatcgggac ggcgttgacc
     1561 ggtgttccag ctgtcattgg tgcttgggcg atgtacatct tccaaagttt gttcaacttg
     1621 gttgttacat caaattcagg acaagcagct ttgactatgc caatcatggc tccactggca
     1681 gatttagtag gtgtatccag acaagtagca gttcttgctt atcagcttgg ttcaggtttt
     1741 atggacgctt ttacacccgt atcagccagc ttgattggtg tgctaggtgt tgcacggatc
     1801 gaatgggcaa aatgggcaag attccaaatc aagatgcaag gattcctgtt tgttttagga
     1861 actattttca tcatgattgc cattgcaata ggtctgcagt agtactggag acctgtaaat
     1921 aaaaaagtaa tccaaacagt agataaggac tccaagaacc gtcattttac ggtaaaatca
     1981 aaggagtaaa gatcctatcg tttggattat tttttaagat cctatcatca gttatactta
     2041 aagaaagagg aaaaatgtat gaaaatcatt cgacaaattg aagtgtttgc accagattac
     2101 ttaggaaaaa tggatgtact gattgccggt gggaagattt tggctgtaga agaacagcta
     2161 gaaggcggct acgaaggagt ggaagtagaa gaactttcag gtgagggaaa agtactaacc
     2221 ccgggtttca ttgactgtca tttccatatt ttaggtggag gaggagaagg cggttatcaa
     2281 aatcgaacgc cagaagtcac attgagccaa ttgactacag ctggtgtaac gacagttgtc
     2341 ggttgtttgg gaacagacgg agaaggtaga gatatgactg cgttgatcag caaagcgaaa
     2401 ggtctggaag cagaaggaat ctccacttat gtatacgaag gttcgtaccg attgccggta
     2461 aaaacagtaa cagattctat catcaaagac tttttgacaa ttgataaaat tatcggaatc
     2521 ggagaaatcg cagtatccga tcaccgttct tctcagccaa gttttgaaga gttcgctcgt
     2581 gcagtagcag atgctcgtgt aggaggcatg ttatccggaa aagctgggat catcaatgtc
     2641 cacttaggcg gaggaaaaag aaagctagag ctattgacac gaatcgtaga agaaacagaa
     2701 attccgatca cacaattttt gcctactcat gcaaatcgca caccagaatt atttgaagct
     2761 tgcgtggcat ttgccaaacg tggtggcacg attgacttca ctgctagcga agatcctgat
     2821 ttttgggaga agacagatgg tgaagttcgc ttcagcaaag cactgaaacg attgatcgag
     2881 gaagatgttt ctttagataa tttcacgatg acctcagatg gacaaggaag cttgccttat
     2941 tttgatgaaa acaatcattt cctagggtta ggagtaggaa gtgccaaggc attgctagta
     3001 gggatcaaag aagctgtgca aaaagaaagt atccctttgg aaatcgcctt acgagctata
     3061 accagtaatc cagcacgtat attgaaattg gataaaaaag gaaaaatcga aattggtgct
     3121 gatgcagatc tgtgtatctt ggataaagaa acgcttgata ttgatacagt tatcgctaaa
     3181 ggagaaataa tggtccaaga aaaagaagtc aaagtatggg ggactttcga aaaaagtttt
     3241 taatcaacag ctctaactat cttttttaga aaacgagcgt tctgtttgtc tgtatctgtt
     3301 gttgatgtta ccctgaaggt agatcaataa acaaactaag aggaggaagc acaatggcag
     3361 atttaaaagg acgttctaaa gatatgaaag ataaagtagt cggtgaagga aaagaagcat
     3421 acggcaaagc aacagacgac aagagcaaag aaacagaagg gaaagcacaa tcactaggtg
     3481 ctgacatcaa agaaaaagct cgaaatttag gcgacgaagt caaagacaag ttttctcgaa
     3541 aagacgaaaa aaaataaaaa ccacttatta ctaattgaat caagcaaata aaaaatccga
     3601 accatatctg cgagacagat atggttcgga ttttttattt gatcattatc ctgtttttta
     3661 aacttcgatt ttttgaaatt ttttattttt tagttcaaag acttcatcac agctttttgc
     3721 tacttcaatc tcatgagtca cgatgataat acagcgattt tgttcatggg cgatttcttg
     3781 gaaaagtttg acgatatctt gtgaagttgt ttcatctaga tttccagtag gctcatccgc
     3841 tacgattagt tgatgttcac agcagatagc acgaacgata gcgactcgct gctgctgacc
     3901 tcccgaaagt ttggtcacct gtttttttgc taatatttca tcaattccta cacgagccag
     3961 tcgatctaaa gcaacttgtc gataattctc ttgcttggtc ttagtgattt ccattgctgc
     4021 tatgacgttg tctagagccg ataaataagg aagcaagttg taagcttgga aaataatcga
     4081 gacatcattt ttacgataac ttcttaaccc gattttgttc agtgaacgat cttgatagta
     4141 tacctttcct tcttttggtg catctagtcc agaaataagc gaaagaaaag tcgtttttcc
     4201 agaaccactt gctcctaaaa tagcgtacat ttttccagct tcgaaattca gttctacatc
     4261 tttataaagc gcatcttgcg gatcttgata ccaaaatccc aattgttctg tccgtaacat
     4321 caaattcctc ctttagttta ataggatttt tcttgggttt aatcttaata tccctataga
     4381 agctaaaaag acagaaaaca gactgattcc aaatgctact ccggctaata gtcccaattg
     4441 tgcaggtttg acattgattt ccaattcgct gacttgatca gaaacagcaa atggattatt
     4501 cgtggttcct tgttgaccat cgcgttgacc gccttgttct tgtctgttac ctggcatttg
     4561 tccaccgcca ggagcttgct ggttttgtgt cgtggtttct gtctgttggt caagtagctg
     4621 ctgtcccacg gcattcgcga cgacgtttcc gctaagcgaa gcaactccta atgcaagaat
     4681 catacaaata gccacttcgg taaacaattg gagaatgatt ttacttctgg attctcctaa
     4741 agatagcaag acgcctaact catgccgacg ctcccgaatg gtaatcataa tgatcagagt
     4801 aagtatgata ataccggcta cagccactag taaaacaaca tttttagaaa aacttgccac
     4861 gttgtttaaa ggttccaaca ttgactgata catggaatca tttgattgta agctaaatgt
     4921 atctgtgtcg atcagcttct cagcttcttt gagaaactca tccattttat ctggatcaga
     4981 tagagtgtaa atagcagaat ctatcgtgtt atcgtcagat gtcccattta gttcatttgc
     5041 aaaagtgtaa gaagtgtaaa gtgtattcga cggattcatg aagttgaatt tcatacccat
     5101 actgccgctt gtttcgctgg attcataaat tcctttgatc gtcatttcat aagtggtatc
     5161 ttcatcttca gtactcgtga ttgtgaaagt atctccgact gccaggtcat ttgtttctgc
     5221 tagagtagaa tcaatgacta cattgtttgt gcctttgtcg ctgtcatcta ttccttcacc
     5281 atccgtgatt tttgctgttc catcagaaaa attactattt tgtgcagttg ctgacacacc
     5341 actgatttga aagtctgctt gagtcatttg cggattcccg cccattcctc cagcaggttc
     5401 accgcctgca tcagtagttt ctgaactgtc ttcacttgaa tcagaactag tgatggcagt
     5461 tattccatct tttgccatag ctgaggcgga actttcaaag gaataactct ttacattatc
     5521 taattcagct attttttccg cgtccgttaa ggaaactggt gtaagagaaa aactgcctgg
     5581 atctggacgt tcttcagtgg tagaaccgct tgaagaagtt tgttcctgtt ttttaaatga
     5641 agcttctcga ttggcactta aagtcactgt tgctccaact tctttttgtg cttgattcgc
     5701 tgcttcttct gcagcgcttc gaatcgtgag gccagctagc acaaaaataa gaatggctgt
     5761 gaacacggca aacaataaca atgaacgtcc ccattttact tttgtacttt tccatgcacg
     5821 tttcataaaa ttcatatttt gcatccctcc tagtagatgc atttgataat agacaaccta
     5881 tcttaaagct agcttaaatc ttatgctgtt tgcacaccat caacatgagg ttctgtatat
     5941 ataaaaagtc actatagtta ttgcaaaaaa tgtggtaaaa tgaaaaaagt atgtttcaaa
     6001 ccgacgaaga agaaatgaaa gaggaatagc aaaagaaatc ctagatgcta cagagggatt
     6061 tttacgtgca tagttgttct aacaattgct gatactagcg atttagttta tttgttgtat
     6121 aataatgggg aacagctgaa tacttatata agtattctgg ctatagcgtt tcgcaaaaga
     6181 tccattttgt taatgaagta tatccaaaat aaaatgccca tccaactgtc agaacgcgga
     6241 tgtgctggta attttcctgc tgattctcca taagttgaga aatagtgatt ttgcatatgc
     6301 ttcattggaa tggctcatat atttagataa agaagaaaat cgacatcttt aaacttggat
     6361 gtcataagaa gaggtgaagt ttgtgagtac cattaaaatt atcccattag gcggcgttcg
     6421 tgaaaatgga aaaaacatgt atgtcgcaga agtgggcgag gatattttta ttttagattg
     6481 tgggctaaaa tatcctgaaa atgagttgtt ggggatcgac gtcgtaatcc ctgattttac
     6541 gtatttagaa gaaaacattg atcgtgtagc tggtgtcttt ttaacacatg gacatgcaga
     6601 tgcgatcggg gcacttcctt acttgttgtc aaaaatttct gtaccagtat tcgggacaga
     6661 gttgacgatc gagttagcaa aattgaatgt cagtcgtaat gaagcagcca aaggatttaa
     6721 ggatttccat gtggtagatg agcatacaga aatagacttt ggtgaaacag tagtgagctt
     6781 tttccgtacc actcatacga taccagattc agtggggatc aatctgaaaa caaaagaagg
     6841 tagtatcgtt tatacgggag attttaaatt tgaccaaacg gctatcccaa tgtatcaaac
     6901 agattatgca cgattggcgg aaatcggcaa agaaggagtc ttagccttac taagtgaatc
     6961 ggcaaatgca gaaaatcctc agcctgtagc ttctgaagcc caaatagcag atgaagtatt
     7021 tgatacgatc aaatattggg aagggcgtat catcgtcgct tgtgtagcaa gtaatttgca
     7081 acgagtgcaa caagtattgg atgcagcaga aaaagcacaa cgaaaagttg tcttgactgg
     7141 tcaagatttc gaacgaatta ttcgcacagc gatgcgttta gaaaaacttc aattaccaag
     7201 tgaagatctg cttgttacgt tgaaagacat gaaaaactat gatccagaag aactgatcat
     7261 tttagaaact ggccgaatgg gtgaacccat caagtctctg caaaaaatgg caaacggtac
     7321 acaccgtaat gtcaagattg aagaaggaga tttggtttat atcactacta cgccaagcat
     7381 cgcgatggaa accatcgtgg cgaaaacgga agatatcatt tatcgagctg gtggaacagt
     7441 gaagttgatc tctgagaata tgcgcgtttc tggccatgcc aatcctaatg acttgcaatt
     7501 aatgatcaat ttgatgaaac caacatattt tgtgccagtt caaggagagt atcgtgaatt
     7561 agctgctcat gcagatttgg ctcatgcagt agggatgcca tacaaaaata tctatattac
     7621 tggacgcgga gacgtgctgg aatataagaa caagcgtatg agtgttgcag gaactacaag
     7681 tgcagaaaat gtaatgattg atggattagg cataggtgat atcggaaaca ttgttttacg
     7741 tgatcgaaaa atcttgtcag aagacgggat tttcgtagcg gttgtcacta tcagtcggcg
     7801 agaaaagaaa atcatttcaa aacctcaaat tacttcacgg ggattcgttt acgtaaaagc
     7861 tagccgtgat ctgatgaaag aaagcagcaa tatgattgaa acaatcgttg agaaacattt
     7921 agaaagcaat gattttgagt ggagcaaatt aaagcaagac atccgagatc aattaggccg
     7981 ttacttattt gaacaaacaa aacgccgccc agtgatcttg ccagtcatta tggaagctac
     8041 tcaacgtcga aataaaaaat aaacaaaaag agtaagatga acctctctat agagtgctcg
     8101 tcttgctctt tttttgcgaa aaacaaataa tttttgaata cagcatccct cgctttataa
     8161 taaacgatag aataaaggga gtgaatcaat gatgagtcaa acaaaagtcg aacgttattt
     8221 agaagaacaa aagatcagct atcaaccact tgattttagt catgtggtag aagaatcttt
     8281 cacagaagaa ctacaaaaaa gagggattga tccagctttg atatgtaaaa ctctcgtagt
     8341 gaaaggaaac aaaactgggg tgatcatcgc attgattcct ttgaacgatc acttagatta
     8401 caaaaaaacg agacaagtga cgaaagatcg taaagttggt tttcctggaa tggattttgt
     8461 attaatgcat acaggatatc cccacggagc aaacacccct attggaataa aactcgcaca
     8521 tcctgattat tgttttttag cagacagttc tttaaaagaa aaagaagaag taattgtgtc
     8581 aagcggtgaa atcgggagaa gccttcggat aaaagtagcc gatttagaaa agatcgtcca
     8641 tcctatttac gctgatttaa ttagttaagg gacgagaaga gaagctaagc agagcagaga
     8701 cctcaaactt gagattatat ctgcttggta cttggtgcat cctgtattat ctgttacaat
     8761 tgctttgtac atactgtact atcaatccaa tgaaaatata tttagcagct atattttttc
     8821 attgatgtgc aagtgatgaa atcgttttta ataaaaaaga tacagagaaa acgcgaggtg
     8881 taaaatatga aaattacgta tcatggacat tcctgtttaa caattgaaat ggaaaatggc
     8941 caacgcgtga tgattgaccc gtttattaca ggaaatccat tgacagactt aactgcagaa
     9001 gaagtaaaga cagattggtt gctgattact catggtcata gtgaccacat aggagatatg
     9061 attcctattg caaaagaaaa tcaagccaca attatcagta ttgttgagat tgctgattat
     9121 gcgaacagca gaggagtaga ttcattcggt atgaatatcg gtggaaaaca tgcgtttcca
     9181 ttcggcgtgg taaaattcgt acatgcacag catagttcaa gctatgaagt agacggtatc
     9241 gttcagtata tgggcgagcc tagcggaatt attattcaag cagaaggaaa aacgatttat
     9301 catgcagggg atactgctta tttcagtgat ctaggattgc ttgcagaaga attcgatatt
     9361 gatgtcgctt tcttgccgat tggcgataac tatacgatgg ggccagaaga tgcagcaaag
     9421 gctgcgcaaa caattcgtgc caagaaagta gttccaatcc attacaatac tttccctgtc
     9481 attgaacaag atcccgaatc ttttgtagag ttactggaag atagtgaagg aaaaataatg
     9541 agcgtctcgg aaacgctgga agtgtaggca gaaaatggcg acaaaacatg atttgatttt
     9601 agaatatatt gaaagtttac ctgttggcaa tcgaatttct gtaagaagca tcgcaaaaga
     9661 attgaatgtc agtgaaggaa cagcgtaccg tgcaatcaaa gatgcagaaa atgtcggact
     9721 agtttcaaca attcaacgag tagggaccat ccgtatcgaa cgcaaattaa aaaaacatat
     9781 tgaacgtttg acatttggcg aggtcgtcag gatcattgaa ggggacgttt taggcggggc
     9841 ggcaggatta gacaaggtct tgaataaatt cgtcatcggc gcgatgacta aacatgccat
     9901 ggaacgctat attacgccag gatcactaat gatcgtcggc aaccgggcgg aagtccaaaa
     9961 attagcattg gaagatggcg ccgcagtatt gatcacagga ggattcaata cgactgctga
    10021 gattgcaaag ctagctgatg atcttgaaat gccgatctta cgcacctctt atgatacatt
    10081 tacagtcgca accatgatca accgagcgtt aagcgaccaa ttgatcaaaa aagatatcat
    10141 gcttgtcagt gatatctata tgccagctga aaagactcat tatttgcagc agacagatac
    10201 gatttctgat tatcagcgtt tgtcagaaga aacgcagcat tcgcgttttc cagtcgtcaa
    10261 ccgccatcat cgtttgatgg ggattgttac ggcaaaagat gttttaggga aatcgccaaa
    10321 ccagatcatc gatcgggtga tgacgaaaga accaatcagt gtaaagaaaa caatgagtat
    10381 tgcctctgtt agccatcaaa tgatctggga tgggctagaa gtcatgccgg tcgtttccga
    10441 tgacttgaca ttggaaggct tgattacccg gcaagatgta atgaaagcga tgcagcttgt
    10501 ccagcgacaa ccgcagattg cagatacgat ttcggatcag atatctggaa atatccatac
    10561 gattgatact gaccgtgaag gaaatcgttt ggaaaaccct aagttcaaat tcgtagtagc
    10621 accacaaatg gtcaatggcg ttggaaccat ttcttttggc gtacttagcg aaatcatttc
    10681 tgatgtcgca caaaaaacaa tggtgatgaa ccaaaaacga aatatcttga ttgaacaagt
    10741 gaacctacat tatttgcggc tgatccaatt ggaaagcgaa ttagacattc gtccacgtgt
    10801 attggaaatc ggcagacgtt ccgctaaact ggatatcgaa gtgtttattg aaaacaccat
    10861 cgtttccaaa gcaatcgttg tttgtcaagt aatggaacgt tcttagaaag caggagtgaa
    10921 atgacagtac agcaagaaat agtagataca ataaaaaaat acgataaaat cattatccac
    10981 aggcatttgc gccctgatcc tgatgcatta ggatcacaag taggattagc cgaactatta
    11041 cgggaaagtt tcccagaaaa agaaatacgt caagtaggtg aaacgattga agggcttcgc
    11101 tttttagcag aaatgcaaga agttgaagat gtcttctacc aaggagcgct agtcatcgtg
    11161 actgatacag ctaattcacc cagaatcagt gatcaaagat atcagttggc agaaaaactg
    11221 atcaaaatcg accatcatcc caatgatgac ccttatggag atcttgtgtg ggtaaataca
    11281 aaagcaagta gctgtagtga gatgattgca gaatttgctt tgatgtttcc tgaatcttta
    11341 aagatgaacg ttaaggctgc acggttactt tatgcaggaa tcgtcggaga tacagggcgc
    11401 tttttgtatc cctccacgac gtcccgtaca ttagagattg cttcgatatt gagaaattat
    11461 ccatttgatg caagtgcttt gaacagagag attgaacaaa tgccgatgaa agtcgctaaa
    11521 ctttccggtt atctttatca aaatatccag gtggatgaaa atggtgcagg aagaataatc
    11581 cttccgcaag aaattcttga taaatatgga atcgatgatt cagagacagc ttcgatcgtt
    11641 tcacttcctg gagtgattga cgaagtgctg gcttggggga tttttgttca gcagccttca
    11701 gggtattacc gcgtacgttt acgttctaag gggccgatca tcaatgaatt ggctaaacgc
    11761 catcatggag gaggccatcc attagcaagt ggtgcgaatg caaaagattt agcagaagta
    11821 gaggaaatct ataaagagat ccaagatata tgccaatcgt ataagagcag aaaaacagaa
    11881 tgatacttcg ttcgaaaacg tgccttttgt agtaaaaatc acaaatgtat cttttcaaga
    11941 tcttcttttt ccgttacaat agtgctcact aaagatttta aaggagaaag aagatgacat
    12001 taccaaattg cccagaatgt ggctcagagt acacatatga agatcgaggc ttgttgattt
    12061 gcccagaatg cgggaacgaa tggaacaaag aagaacaaga aactgtcata gaagacggat
    12121 tagtggtatt agatgcaaat ggaaaccgtc tgttagaggg cgatagcgtg acagtgatta
    12181 aagacttgaa agtaaaaggt gcgtcaggtg ccattaaaca aggaacaaaa gtcaagaaca
    12241 tccgtttagt agaaggcgat cataatatcg attgcaaggt agaaggattt ggaccgatga
    12301 aactgaaatc ggaatttgtg aaaaagaatt aaagaatatt caaggtcttt tcacattctt
    12361 ttcctactac taatgataaa ataaagtaaa cgaaaaggag tgaaacgaaa atgtatggtt
    12421 atggaatgta tggtttttta gatccgacat ttcttttggt cattcttgga ttagttattt
    12481 ccggaattgc gtcagcgtac gtcaatagta ctttccgaaa atacgatcaa gtgagaagca
    12541 aaaacaatgt gactggtaca caagcagcac aatatatatt acaaagtcaa cagataaata
    12601 atgtcggtgt tcaacaaatt gccggagatc tcacagataa ctacaattca ggtaataaga
    12661 tgttgagttt gtctcaagca actgcacagt ctacttcagt tgctgcgata ggtgtagcag
    12721 ctcatgaatg cggacatgcg gtacaagatg cttcgggtta tgtcccattg aagattcgtg
    12781 cagcacttgt tccagcagct aactttggtt cgatgatttc gttccccttg attatggtag
    12841 gtgtattgct tagctggaac tctacgttaa tcaatatcgg gattttcgct ttttctttag
    12901 cattactttt ccaattggtg acattaccag tcgaatttaa cgcgtctcgg cgagcaatcc
    12961 aaattttgag tgaaggcgga ctactgacgg aagaagaagt accgatggca agacacgtat
    13021 tatttgcagc agcactgact tatgttgcag cagcgctttc gacattcctg cagctgttgc
    13081 gcttgatctt attgttcggc ggcaaccgaa gagattaaaa taaagaagtt gtgaaatcag
    13141 cgctttgatc tgagctaata ccgagagtta gctgattgaa taccatttat ttggaataag
    13201 aggatgtgac aagaattttg tcacatcctc tttgttttgt tctcataacc ttttttcata
    13261 tacagttcat gaaccgcttt tattaacttg ccaaataaca ctgtattgtg cgttgtatcc
    13321 agatagaaag tctccgtttc atctgaaatt ttctcatgct gatctgtaat gatcaaatca
    13381 gcatgttctg aatatgcggt aattttaaca gcatctttgc gaaataactg ctgcaaatgg
    13441 ctttgaagat gataatttcc tgtaaactgt ttggttatct gcaaatggat gagtaactgc
    13501 tctttcgttt ctgtttgtag taagtgttgg atcaattgac taaggtattg actgatttgg
    13561 tttctttccc cattttttga aaaaattgta tcgatttttt ctcttaattt cttttcctgt
    13621 ataaaagaac tagaatgatt ggacgtggct tctggaaagc aaagtgtaga aaaactactg
    13681 ctggattcac ccaacagttc gaaaaaaaca actgccaaca caagaaaata aaaataaatt
    13741 ggtattttat tttctaaatg gttgagagga aactgttgag ttaagtaagt catcaattga
    13801 ccgacttgtc gacaaataag gtttttgctt gtggaaaata aaaaaccaat ctcctgtttt
    13861 tgtcgaaaag agatttgatt tggaaaaaaa caatagaaaa aataattaaa gtaggctctc
    13921 tctgtttctg tctcttcaca agggcgactc actgaaaaag aagtaaagta ttctgaataa
    13981 tcatgtgtat gctgcaataa gtccatcaat tcagtgattt cagaagaagt ttttggaaaa
    14041 tatgcctgtt gtttgtttcg taatatgaat aaagttaaca gcaagtagat atttttttct
    14101 tgttttgaaa ttttttctat ttgctcatct gtactgttca tttttagtgc atttaattca
    14161 agtgaggaaa atggccaatc gttacctcca aatgtatctg aaagaaaaaa gtaaagatag
    14221 agacggatag ataactcatt tccttcaaga gtacagcaat tttttacaga taggatccgt
    14281 aaatggaatt ttattaagga atgattgagc tgttttgtca gtttttcgag ataggagggc
    14341 gatatataaa gttgttcaag taaatatttt tttggtacag cagtttgtgg ataattgatt
    14401 agtaacatca aatagttaaa acgattggat tcttttaggt agcataattt taacttagaa
    14461 aaaacagcta actttttagt ttgatcggtt tctttggttt ggatctctcc tttatgatta
    14521 gaataaataa attcatcaat caataaaaat tgcttgagtg atacatttat ttttcggatc
    14581 agttctttga ttgtccgttt tggaatatgt aagtcattgg ataattcttg taaagaacaa
    14641 ttattttttt gaatgaccat ttgtagaaca agtaactctt tttttcttgc ttcaattagc
    14701 ataaatacct cctttttatt ctgtttttgt atatagttag acaaaaactg tgagtggaaa
    14761 gtcatttcag tctgtgttat tctcacagag tgtcgccttc ttttttatat aacgttattt
    14821 aatttttttg ttaccttgtt tattctattg tttatttcct agggtatttt gtcaagatat
    14881 tcttgttttt aaggcggaaa aattgat
//
LOCUS       DAZAOD010000063        14609 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000063 DAZAOD010000000
VERSION     DAZAOD010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.064"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(190..756)
                     /locus_tag="ACHDPO_001940"
     CDS             complement(190..756)
                     /locus_tag="ACHDPO_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFN3369555.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(756..1712)
                     /locus_tag="ACHDPO_001941"
     CDS             complement(756..1712)
                     /locus_tag="ACHDPO_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFN3369556.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(1712..2368)
                     /locus_tag="ACHDPO_001942"
     CDS             complement(1712..2368)
                     /locus_tag="ACHDPO_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFN3369557.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            2738..4756
                     /locus_tag="ACHDPO_001943"
     CDS             2738..4756
                     /locus_tag="ACHDPO_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFN3369558.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    4826..5032
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5183..7597
                     /gene="leuS"
                     /locus_tag="ACHDPO_001944"
     CDS             5183..7597
                     /gene="leuS"
                     /locus_tag="ACHDPO_001944"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFN3369559.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            7945..9498
                     /locus_tag="ACHDPO_001945"
     CDS             7945..9498
                     /locus_tag="ACHDPO_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFN3369560.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(9879..11663)
                     /locus_tag="ACHDPO_001946"
     CDS             complement(9879..11663)
                     /locus_tag="ACHDPO_001946"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369561.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(11678..13399)
                     /locus_tag="ACHDPO_001947"
     CDS             complement(11678..13399)
                     /locus_tag="ACHDPO_001947"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369562.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13499..14260
                     /locus_tag="ACHDPO_001948"
     CDS             13499..14260
                     /locus_tag="ACHDPO_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFN3369563.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4743 a         2702 c         2912 g         4252 t
ORIGIN      
        1 gctgtcctgc atcaagtaat aagaacagcc aatcaaaaac agcttctcat gtttttgatt
       61 tggttggact tattaccgca gatataagct tttgagcacc gtgaataaag aggttatgaa
      121 atcaacgctc taacctgagt attagagaaa aaaacgcaaa acatatcatt tatgttttgc
      181 gttttttatt tatctttttt tctcaataca atataaaata ggcggctggt tcttttggtt
      241 gataaaccga taattcagca cattatatgt ttcctgtggc agtttggaac aaaaagaatc
      301 aaccatatcc agttcttttt ctccaccttc atgaccatag tagacgacaa ggatcaatcg
      361 tccgcgaggc acaagtcgtt tcaatatttc ttccatagct gtgcgtgtag tctctggcat
      421 agtgatgatt gctttatcac tttttgggag ataccctaga ttgaaaatcc ctgctttgag
      481 attttgttgt tcagctatca cttctcctaa cgtttcgtgg ccttgtagaa acaatgagac
      541 acgttcttct aactgacgct gttctagcct ttcacgagta gcatcgattg cttgttgctg
      601 gatatcaaaa ctatagacat gaccagtttt tccgatgtgt tctgctagaa aaaccgtatc
      661 gtggccattg cccatcgttg catctacgac gtgatcccct ggttgcaaga tttcttgcag
      721 taatgtatgg ctgaaatgca aagcagtttg caacatcaga cgctcacctt tttccgtaca
      781 tcatattttc cttggaagct atctctgcga agaagttctt catcaattgc attcaagact
      841 tcccattttt tcaagctcca cattggtcca atcaaggaat cccacggcgc atcccctgtc
      901 aaacgatgga tgatgatctc ttttggtatc atttccagct ggtcgcaaat gacattgaca
      961 tagtcaggac ggctcattaa ttgaaggcga ccttcatgat agtcccgcaa cattctcgtt
     1021 ttgcgcatca gatgcatcaa atggagcttg attccttgga tatctgaatc taaaatggtg
     1081 cgtctgacat tttctttcat catttctaaa ctttcgcctg gtaatccgtt gatcaaatgc
     1141 gtacaaacac ggatattatg tttgcgtaat ttagccacgc catctaaata agtttgataa
     1201 tcatgtgctc ggttgatcag ttttgaagtt tcttcaaaag ttgtttgcaa tccaagttct
     1261 acccataaat acatccgctc gttcagttca gcaaggtaat caactacttc atctggcaga
     1321 caatccggtc gtgtaccgac tgataatcct acgacacctg gtaaattgac tacttgctca
     1381 aatcgttctt tgattatttc aactggcgca tgggtgtttg taaaattttg gaaataaacg
     1441 atgtattgtt ggacatgagg ccatttttga tgcatcatgt cgatttcttt ctggaattgg
     1501 attggaagag ggtcttcagg tgcaacgatc atgtctcccg aaccagatac actgcaaaaa
     1561 gtacaaccgc catgggcaac agtcccatct cgattcggac agtcaaatcc tccatcgatc
     1621 ggcaccttga aaattttccc gccaaactca tttcgtaaag cgtaattcca agaatgatat
     1681 cttttatttc cttctgaata aggaaaagtc attaaaagtc cttctttctg taagagttat
     1741 ctatttgttt tcttttttct ctatacactg gataagtcag gcacagccaa gaaagactga
     1801 gtaagtaacc gccgatgata tcagtaggaa aatgaacgcc cagataaatg cggcttatcc
     1861 cgacacttac tataataaac atcatcagca attgaagcaa tgtgcgtaag gttctttttt
     1921 gaacaaaagc tggaagcaga aatagtaaag aaccgtaaag aatcatactg cctgctgcat
     1981 gtccactagg gaaactgtaa cttgtttcaa ctactaagtg cgccaatgaa ggacgctctc
     2041 gcatgaaaaa tagtttgatc accgggttga tgattccagc aattacaata aatccagaaa
     2101 cgaaccaaaa tgtttctgcc ctttttttct tataccacat ccataaagcc gcacaagcaa
     2161 ataaaatgat gacggtaaga ggattaccga atttagtcat aaagagttgg tagctgttca
     2221 gatcaggata agaagctctg acaatgcctg taaaccactg atcgaaacca gaaagccacg
     2281 acagatggaa ctttacgatc cagcccaaaa tgaaaaacag gacaagaaag aagctaccag
     2341 ccacctgaaa tgatgtttta tatttcatac aattcctcct ttgaagcaat gacttattat
     2401 agcatttttg gtccagcgaa aaaaacggta aagagataaa accaatgtat gattcctctt
     2461 tgaataacca atattcttat aaaaaaaata actgtaatcg gaaagacatt ttttggtaat
     2521 gcaaatgaaa tgttagggaa ataaaatcag tgtttttcga aatcctttta aacaagaacg
     2581 tagacgtagg aagaacttga aaatgaacag aagttgttca ttacggtaaa ttacaatatg
     2641 attacaaaaa acaacaaagc tcttaaataa cttttaataa atattaagag aagttataat
     2701 tattaataat agataaattg aagttggagg atagaagatg gaaaacattg caagaaaaga
     2761 acggagacgt ttagaacaga ccaaacgttt tcgaaaagca aaacgagggg cagcaatcgt
     2821 gggaactgcg atggtaggct gttctgtcgc tgccccatta gtacagccgg ttcctgttca
     2881 agcggatgaa acacctgttc agttcggcgc aagaatcaat acagcggcat ttatcacaga
     2941 aattgctact tatgctcaac caatcgctca agccaacgat ctatatgcat cagtgatgat
     3001 cgcacaagca gttgtagaaa gcggttgggg cagtagtgcg ttatctcaag caccttatta
     3061 taatcttttt gggataaaag gcagctatca aggacaaacc gtctacatgg atacgcttga
     3121 atttttaaat aatcaatggg taaataaaaa ggagcctttc cgacaatatc cttcttttgc
     3181 tgaatctttc aatgacaatg cctatgtact tagaaatact tcatttggca acggttatta
     3241 ctatgccggt acttggaaga gcaacacgaa atcctataca gatgcgacag cttgtttgac
     3301 agggcgttat gcgactgatc ctggttacgc aggcaaatta aataatatca tcgcaactta
     3361 cggattgacc caatatgata caccagctag cggaaacgca ggcggtggag cgactacagg
     3421 tggcaataat actggaagtg caggtagtac tggcggttca agcaattctg gtaatacaaa
     3481 ctcaggttca gcaacttcga ccacttatac tgtccaatct ggtgattctg tttggggaat
     3541 ctcaaataaa ttcggtatca caatggatca attgatccaa tggaacaaca tccaaaacaa
     3601 tttcatttat ccaggacaaa aactgacaat caaaggtagc caggaaaatg gctcttcgac
     3661 gaataattcc ggtaacaata ccaattcttc aggaaatgct ggtacatcaa acggaggaca
     3721 aacaactggt gcgaaataca ctgttcaatc tggtgattct gtttggaaga tctcaaatga
     3781 tcacggaatt acgatggctc aattgattga atggaacaat atcaagaaca atttcgttta
     3841 tccaggacaa cagctaatcg tatcaaatgg cggttcttct aatgctggag caaatactgg
     3901 ctcaaatact gggaatacaa gtggctctag ttcgtccagc tcaagttctt ctaatacagc
     3961 ttcaggaacg aaatatacag ttaaagccgg agactctgtt tggagcgtct caaataaata
     4021 cggaattacg atggctcagc taatccaatg gaacaatatc caaaataact ttatctaccc
     4081 aggacaacaa ctgactgttt caaacagtgg atcaacaaac agcacgtcag gtaatacagg
     4141 ttcgtcaacc aatacaaata acagcagttc agttaatact ggcagcagtt cgtctcaagg
     4201 cacttatacc gtgaaagcag gtgaatctgt ttggagcgtg gcaaataaaa acggcatcac
     4261 gatggatcag ttaatcgaat ggaataatat caaaaacaac ttcatttatc caggacagca
     4321 attgatcgtt aaaggtggaa cttcggcaaa tacaaataca ggttcaacta cttctgcagc
     4381 gaaaccaaat acaccgaata cgtctgctac gacaagtaca tcatccactg gtaatacgat
     4441 gtataccgtg aaagcgggcg agtcagtttg gagcgtagcg aacaaacatc atatcacgat
     4501 ggatcagtta atcgaatgga ataatatcaa aaataatttc atctatccag gacagcaagt
     4561 gattgtgaag aaaggttcat ctcaatcaac aaaccaacaa tcagttactg gttcgaaaac
     4621 ctatactgtg aaatctggag aatctgtttg gagtgttgct gacagtcatg gaattacaat
     4681 ggctcaacta atcgaatgga acaatattaa gaacaacttt atttatccag gtcaaacgtt
     4741 gattgtagct aaataaaata gctgttcgaa gaaataacga ttgaattcca caaaaatatt
     4801 tgttactata aggctactta aatatgacaa cacttgaaaa ggaagtagta aaaagactga
     4861 agtttcagag agcgcatggc tggtgagaat gtgcacggat gcttttgaac tcgcctttga
     4921 gttgcccttg ctgaataccc gagtaagcaa gcggcggtga cggccgttac aacgttcgag
     4981 gccttttcac taaggtaaaa ttaggtggta ccgcgtagat tacgtcctat aaaaagagca
     5041 atctttttat aggatttttt tatttctttt gtgaagtttg agaaaacaaa gcaaaaggaa
     5101 ataaaaataa acagattctg ccggtttttt cgttatattt ataatagaaa caagtgtttt
     5161 caatagaaca ggaggacagc aaatgagtta caatcataaa gaaattgaga aaaaatggca
     5221 aaaatactgg gcaaaaacga atactttcaa cacccatgat gatcctgaaa agccaaaatt
     5281 ttacgcactg gatatgtttc cctatccatc cggtcaaggg ctacatgtag ggcatcctga
     5341 aggttatacg gcaacggata tcctttcacg tgtgaaaaga agtcaaggat acaacgtgct
     5401 gcatccaatg gggtgggatg cattcggtct gcctgctgaa caatatgcgc tagatacagg
     5461 aaacgatcca gctgagttta cccaaaaaaa tatcgaaaca ttccgacgcc aaatcaattc
     5521 tttaggattt agttatgact ggaatcgcga agtgaataca actgatccgg agtattataa
     5581 atggacacaa tggatcttta cgaagcttta tgaaaaaggt ctagcttatg aagcagaagt
     5641 agcggtaaac tgggtacctg aattaggaac agttatttca aatgaagaag tgatcgatgg
     5701 gaaaagtgaa cgtggtggct atgatgtagt cagaaaacca atgcgccaat ggatgctgaa
     5761 aatcactgct tatgctgatc gcttattgga tgatctagaa ttagttgatt ggccagaaag
     5821 cattaaagaa atgcaaagaa attggatcgg tcgttcagta ggagcaaata ttgaatttaa
     5881 agtggctggt acggataaat cctataccgt atttacgaca cgaccagata ctctattcgg
     5941 tgcaacttac tcggttcttg cacctgaact agatcttgtt agagaaatta cgacccctga
     6001 acaaaaagct gctgtagaag cttatatcga agagacagct aaaaaatcag atctaaagag
     6061 aacggatctt gcaaaagaaa aaacaggagt atttactggt gcttatgcaa tcaatccagt
     6121 taatggcaag gaaatcccaa tctggatcgc cgattatgta ttatcttcat acggcacagg
     6181 agccatcatg gctgttccag cacatgatga acgtgacttt gaattcgctc aaactttcgg
     6241 actagaaatt cttccagtta tcgaaggtgg agatgttgaa aaagctgctt acacagaaga
     6301 tggtacgcac atcaactctg aatttctaga cggcatgaac aaacaagaag caatcgataa
     6361 aatgaatgaa tggctagaag aaaatggcgt agggaaaaaa gaagtcagct atcgcttacg
     6421 tgactggcta ttctcccgtc aacgttactg gggtgaacca atcccaatca tccattggga
     6481 ggacggaaca gtcacagctg tcccagaaga agagctacca ttacggttgc ctaagacaaa
     6541 aaacatcaag ccaagcggta ctggagaatc tccattagca aatatcgagg agtgggtcaa
     6601 tgtcgttgat cctgtaacag gtaaaaaagg ccgtcgcgaa acgaatacaa tgccacaatg
     6661 ggcaggaagc tcatggtatt acctgcgtta tatcgaccct cataacaaaa aagaactagc
     6721 agattatgaa aagttgaagc gttggctacc agttgacatc tacattggtg gagcagaaca
     6781 tgcggtactt catttactat atgcacgatt ctggcataaa ttcttatacg atatcggtgt
     6841 tgttcctaca aaagaaccat tccaaaaact atacaatcaa ggaatgatct taggcgaaaa
     6901 caacgaaaaa atgtcaaaat ctcgtggtaa tgtagtcaat cctgatgatg tggtcgaaac
     6961 ttacggtgca gatacactgc gcatgtacga aatgttcatg gggccattag atgcttcgat
     7021 tgcttggagc gaaaatggct tagaaggaag ccgtaaattc ttggatcgtg tatggcgttt
     7081 gatcgttgat gagaacaata aaatgcgtga ccgtatcact acattgaatg atggcaagct
     7141 tgataaagtg tatcatcaaa cagtgaaaaa agtgacagaa gactatgaaa atcttcattt
     7201 caatacagca atctcccaat tgatggtctt tatcaatgaa gcctataaag tggacgctct
     7261 gccttatgaa tatatcgaag gatttgttca actactcgca ccgattgctc ctcacatggg
     7321 tgaagaacta tgggcaatcc ttggaaatga tggtggtatt tcttacgcac catggccaac
     7381 atacgatgaa gcagcacttg ttgaagacga agtagaagtt gttttccaag taaacggtaa
     7441 agttcgtgcg aaaagcaatg ttccccgaga cttaggaaaa gatgagctag aaaaagcagc
     7501 attagccaat gaaatagtgc aagaatatat tgaaggcaaa acagtcagaa aagttattgc
     7561 ggtaccaaac aagttagtca atatcgttgc taattaattg gctctttgtc aataaggact
     7621 gatgagttgt gcaaaatcaa atctgggcca gaatgaactt cattctgtct cagatttttt
     7681 gttatttcaa attgattaat tgattgatca aaaaggtttt gattttcatg ttctcaaaca
     7741 cgttcaatgt ctttttcttc tgaatggtct tgtaagagat ctctgtaatc atcaaatttt
     7801 tgtctattaa tcttagtatt ttttgatgta taaactacct gaaattgaga gtacatacca
     7861 aattcataaa ttttttatta gtgggactag tgattgtatg gattttgacg cataatgaat
     7921 gaagtatgag aaaaggagag acaaatggat caagaactat ttattatcga agtattatca
     7981 gctaaacaaa aaattatcga gaaagcgaaa aaaagagcga aaagaataat gttcaagctt
     8041 ttaagcttag tatttttctc tggtttgctt tttttcggag ctgtatcgtt cctatatcgc
     8101 catatgagtg cagtagtccg ttcagctgaa gggatgcaaa aattaaataa tttgtatcac
     8161 ttttcgtggg gagttggcgg aataacaatt gttgtgctta ttgtttttct tctacttatt
     8221 tggctccgtt accatcaatt gtcgcgtcat ttcgatcaat ggcttagtca aagagcacaa
     8281 cagtttttac ataataaacc aacttctcaa gatgatgact atctttattt tgagaagact
     8341 tcgacgagtc aagcttttcg gatacaaaaa agtgattgcc agttattgct gagatcactt
     8401 gatgatttac ctatctactt aggcgaaagc aaatcaaaat tcggaatgaa cacattccat
     8461 atttttttac tagaaaacga acccagatgg gaaaaaagcc agtcttcgcc tggtggatac
     8521 ctgacaacta agatgagtac attagtcact ggttttttcc tcattctttt agctggaaca
     8581 atctattatg ggagatacac tcagccaaaa atgtcttctc atataaatgc tgcttctcac
     8641 atgacaatga actcaactaa cgatacgcat atacaaaaga caaatgaagg gttgttagct
     8701 gatcctaagc aaaaggtaaa tttgacaaca caaaagataa atgatctcaa acttgataca
     8761 gagacgcact ctctctatat gacaacagat agtggtgcta attgggtatt tgtgccgatt
     8821 gattcgcaat ggttgcgttt tggcgaatac accctgacaa cggggctgat tcctgaaggt
     8881 tattggatgg acaacacata tgatatttcc gccgatttct catggtttat ctattcttct
     8941 ggggatgatg tacgtctgct gacttcaaga gataatggta aaacatggca aacgtctatt
     9001 atcacccaat cagttcagcc gatacgttat cgaaaagcgg tattttatgg caacgatggt
     9061 ctatttatct gtacatcagc cagtgggatg tctgcagaaa ctttgtacat ttacactact
     9121 atggatggcg gaatcacttg gataaaaagt ggaagtacaa tgatcaatca gccagtacaa
     9181 aatgtcagct tcgttacaac ttctttaggt tttgtttcga cacgtgaaag tttgttttat
     9241 acaaacaacg gaggacgctc attcaaagaa tcagttctgt cgattccgga aaactatcag
     9301 acagggggga tagatctttt tcaatcacca aatgaagtta ctcaaataag cgcgaatacg
     9361 ttagagacaa aattttattt gttgaaaaaa ggaccaatcg atgcagggaa aatgtttgcc
     9421 tgcctcttcc gttcaactga taacggggaa acatggcaat tcgttcagca actatcgcaa
     9481 gtagaacaag gagattaaag aagagagatt gtgagcctga cgttcagcac cgagtcacaa
     9541 gaaacaaatt caaaaaacag cttctcatat ttgttgaata gtgtaactcg tgattcggag
     9601 ttgacaagag caacaagaag cgattttgaa gtatagcttc tcgtatttta caagatcgtg
     9661 tcttattgcc gataggttgt ctcttgaaca ccgtttattc gtaaaaaggg attgtgacaa
     9721 gtcttttgtc actacttacc gaacgaaact gaaggagcta tccaaaaagt atcattagta
     9781 ttattctttg tgtttctagt ggcaccacta gtacatttaa aaaagctatc gatcatggac
     9841 taatcataca tgatcgatag ctttttagat aatgtttgtt acgctatctg aaattgacta
     9901 ttataaagac tggcataaag cgttggtgat tggagtagtt cagaatgtgt tcctttttcg
     9961 acgatatcgc cattcttcat tacaaggatc atgtctgcat tttcaatcgt tgacaaacgg
    10021 tgtgcaatca caaaacttgt cctatctttt gtcacagctt ccattgcttg ctgaatcaat
    10081 gcttctgttc gtgtatctac gctagaagtt gcttcatcta aaataacgac aggaggattc
    10141 gctagaatga ctcgagcaat tgtcaataat tgttgctgtc cttgagataa cgtgccgttt
    10201 tcgctagaaa tgatcgtatc atatccgtct ggcagtgttc gaataaagtg atcacattgt
    10261 gcgatttcag ccgcttcgat aatttgttct cttgtggcat ccattttccc gtaggcgata
    10321 ttatcagcta ccgttccttc aaacagccag gtattttgta aaaccatccc aaaagaacga
    10381 cgtagttctc cacgtgaaag cttggtaata tcaagaccgt cgaattcgat ctttccttta
    10441 ttcagttcat aaaaacgcat cagcagattg actaaagtcg tttttcctgc accagttgga
    10501 ccaacgatcg ctaccgtttg ttttggcttt actgaaaaat cgacttgatt catcaatatt
    10561 ttatctgatg tgtaaccaaa ctgtacattt ttgaaagcta tttttccttt cggttgttct
    10621 aaaagtcttg catctggaag gtctggaatt tcatctgttt catctaatat ctcaaatatc
    10681 ctatcgattg ctgccattgc ggattggatc gagttgatca cataagaagc ggtagaaatt
    10741 ggttcagaaa tctgattgat gtactgaaga taagcttgta agaagccgat cgtcacacca
    10801 cctgatagaa caagcatagc accgaatacc gcacttatga tgaaggcgag ttgattaatg
    10861 aaacgaatgg ccggatagat agcacagttc ataaattgag cacgtttaaa agcgttgtat
    10921 tgctttttat ttacttcgtg tatagcagct tctgcatgag cttgctgatt gaatgttttg
    10981 accactagat taccagctaa gatttcttcc attcgattat ttaaaacacc cagttcatac
    11041 tgattctgtt cagaaatctg tttgtttttg ttcgcaatct tagttgtaac aattgaactg
    11101 ccaacgatca gcaataagac gagcaaagta agcttgcttt cgatataaaa cagcatcaga
    11161 ccagcagcag ctattgttac gacagaagta aaaaattgat tgatacctgt caataacact
    11221 tgagaaagtt gattgagacc ggtagttgtc cgactaatga tgtcacctac ttgatgattg
    11281 tcaaaaaacg acatcggtaa tgttttgaat ttttttgtga tttcttttcg caccctcaat
    11341 gtgatctttt cgcttaacgc tgccattgtc cgttcctgaa taaatgaagt gatgctgctt
    11401 aagactgaac agccgatcag caataagaca gggaacaaca atgcttgttt gatatcactg
    11461 aaagaaagct gtccaatacc tgtttttctt atttctgata agagatcatc gatcccgatt
    11521 cccatgatca agggcatggc tacgactaat aggttcccga ataaactgca tagaaacaat
    11581 ccgtaaaaat atttatgttc aggtttgatc attttccaaa aacgtatcaa agcacgcgtg
    11641 ttcaacgttt ttttcttttc catcgtatcc cttctttcta tattccttgt gattttgcaa
    11701 actcctgata agtttggcaa ttagacagta gttcttcatg agtaccttgt ccaacgattt
    11761 ttccttcatc taaaacaatg atgttatctg cttgttggat tgtactgagg cgttgagcaa
    11821 caatcacgag agttttctcc gacatgtgtt tatgaagggc tgctcttaat gctgcatctg
    11881 ttttatagtc taaagcggag aaactatcat cgaatacata gatctctgct ggtttgatca
    11941 acgctcgagc aatacatatc cgctgtttct ggccccctga ataattagaa ccgccttgag
    12001 caacaaagct gtccaatccg tcaggaaggg tgtccactag ttcttctaat tgagcgatct
    12061 tgatcgcttt agacaactct tctgttgagg catattcatt tcccatctgc aagttgctta
    12121 aaattgtccc gctgaataag aaagccttct gagggacata actgatgtgg gagcggatct
    12181 gttcttgagt catttgagta agaggaatac caccaagggt tacttttcct atcgtagggt
    12241 cactaagtct caagagaagt ttcgccaaac tactttttcc agatccggtc ccgccaacga
    12301 tcgctgttgt ttttccttta ggtattgtga aatcaatatc ttctagaact ggatcagaga
    12361 tttcagtata tttaaatgtg acatgttcaa aagcagctgc atttgtctga tcaaaggttg
    12421 gttcagctac tgttttgatc gtctcttcct caatttcgat ctctgcttgc agtatttctt
    12481 ctatccgtcg taatgaggca aacgatttag ggataatgac caataccata gctgcgatca
    12541 tcaagtaagc aagtgtcagc atagagtatt cgactacagc agtcacgaca ccgatttgta
    12601 atgctccttc tgctacaaga tttccgccaa accacaaaat agaagcataa acgattccca
    12661 tgagcaaaaa agcaattgga gtgacccaag caaatattcg gttcactttg atcatttgat
    12721 tagcatagtc agcaaagctc ttattcgttc gcttttcttc atatgattga ttatcaaagg
    12781 cacggatcat attaatccca gtaaagaatt ctctcaatgt gatggtgatc cgatccattt
    12841 ttggctggat actcaaagat aaaggtgccc ctcgtttcat cagtcgataa acaatccata
    12901 cataaaaaac aacagagatc aatgtaaccc atgttagtaa tagagaataa cgaaacatca
    12961 tgagaatggt gaaaacgcaa ataaccggtg ctggtaagat catttggcaa aataaaacaa
    13021 tcatttgctg gacattatcg acatcattcg tcattcttgt caaaagagat ccagaactaa
    13081 aacgactgat atccttcatt gacagctgtt ggaatttacg gaaatatttc tcccgcgttt
    13141 ggaatccaaa cctagcggaa gccaatgctg aaaagtaact agaggcaact gcagcgattg
    13201 ttcctagaaa cgctacaagc agcatttcaa ctccaatttt ttttataact gaggcttcgc
    13261 cacttgctat acctgtgtcg atcagctttg ctactaattt tggtacacct aatgtaccgg
    13321 cgatttctaa acagatcatc acaaaggtaa ggagagcgag tcctttgttt ttctgtaaga
    13381 atgtttttaa gatagacata ttattcctcc ttttttcctg atacttttcg attctatacc
    13441 ttcaagtaac ttgaaggtca atagaaaaaa gaataaactg aaaaagaggt gagaaaaaat
    13501 gaaaaaaatg tatacgattg gccaagtatc ggaactattt gatttgccaa aatcaacgat
    13561 ccgctattgg gatgaacaag gattaatccg ttcaagtaga caagaagaga atgattatcg
    13621 attgtttgat atcgatgata tttttatgct ttatgatatc gttttttata gaaaattaga
    13681 tataccgatc aaacagatga agaatttata tggaaaaaca ttgacggagt tatatgagac
    13741 acttgatgaa acagaaagaa gaatccataa agaactggtg gtgatgaaac aaaaacaaaa
    13801 agagataagg gagcaaaaaa aacagttgaa attgatgatc gatacaaacg aggaagaatt
    13861 tcctgtagaa gagatccctt ttgactgtat gatctcaacg gagtttgaag atattgtgga
    13921 aatcaaaaaa tttctaccta actattcaag ctttgggatg atgagtatgc cagcttccag
    13981 ttcacagacg atgtatggat tttttatcga ccctagtgaa gtacatttat ttactcaaga
    14041 cgtgatttgg gagaaaaaag atacggctgt ttatcgtcga ttcttattga aatccgagat
    14101 gaaccatgcg gaacgtaata atattttaga aatcagagaa agaatgtatg aaaaaggatg
    14161 gaaaacagga gaagtgatcg gccagtatct attgacgaat acggatgaaa acaatatcag
    14221 aactgaatat tatcatgcat ggatagaaat gaaaaaatag gaaatatgtg tttaagataa
    14281 ctcgaaaatg atggttgttt tagttataaa gaaaaatttt ctggttcgat tacgggttta
    14341 atgtggggga ttattagtcg tggatagata gaattttagt tttttagagg aaatatgtct
    14401 ttaaaaatgg aatggttgca attcttagcg atatatacga tgtaattgtc ctcttaaaaa
    14461 agtatggaaa aataattgta ttgggtgtta tgtataattc atggtgaact gagactaatg
    14521 agaagaaaaa ttcatattgt tatgagtgag attgtatcag atgagaatga taaattaaat
    14581 aggtgcataa aagcattaca cttaaaata
//
LOCUS       DAZAOD010000064        14488 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000064 DAZAOD010000000
VERSION     DAZAOD010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.065"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            372..560
                     /locus_tag="ACHDPO_001949"
     CDS             372..560
                     /locus_tag="ACHDPO_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFN3369564.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            638..1651
                     /locus_tag="ACHDPO_001950"
     CDS             638..1651
                     /locus_tag="ACHDPO_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFN3369565.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(1718..2752)
                     /locus_tag="ACHDPO_001951"
     CDS             complement(1718..2752)
                     /locus_tag="ACHDPO_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3369566.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            2867..5092
                     /locus_tag="ACHDPO_001952"
     CDS             2867..5092
                     /locus_tag="ACHDPO_001952"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFN3369567.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            5110..6993
                     /locus_tag="ACHDPO_001953"
     CDS             5110..6993
                     /locus_tag="ACHDPO_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFN3369568.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            6974..7948
                     /locus_tag="ACHDPO_001954"
     CDS             6974..7948
                     /locus_tag="ACHDPO_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFN3369569.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            8607..9629
                     /gene="aroF"
                     /locus_tag="ACHDPO_001955"
     CDS             8607..9629
                     /gene="aroF"
                     /locus_tag="ACHDPO_001955"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFN3369570.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            9662..10726
                     /gene="aroB"
                     /locus_tag="ACHDPO_001956"
     CDS             9662..10726
                     /gene="aroB"
                     /locus_tag="ACHDPO_001956"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFN3369571.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            10728..11894
                     /gene="aroC"
                     /locus_tag="ACHDPO_001957"
     CDS             10728..11894
                     /gene="aroC"
                     /locus_tag="ACHDPO_001957"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFN3369572.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            11911..13002
                     /locus_tag="ACHDPO_001958"
     CDS             11911..13002
                     /locus_tag="ACHDPO_001958"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFN3369573.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            13015..14310
                     /gene="aroA"
                     /locus_tag="ACHDPO_001959"
     CDS             13015..14310
                     /gene="aroA"
                     /locus_tag="ACHDPO_001959"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFN3369574.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            14303..>14488
                     /locus_tag="ACHDPO_001960"
     CDS             14303..>14488
                     /locus_tag="ACHDPO_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFN3369575.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESD"
BASE COUNT         4702 a         2655 c         3207 g         3924 t
ORIGIN      
        1 attattttgg cgatttgcca ataaggactg ttgagttgtg caaaatcaaa tctgggtcag
       61 aatgaacgtc attctgtctc agatttttcg ttatttcaat ttgattaact gattgatcaa
      121 aaagattttt attttcatat tctcaaatga ttcaacacta aatatacatg tttgacgcgg
      181 aaattattat tcgattttgg cggcatcagg ggggatgacg acgtagcaga cccattattt
      241 tactcaagaa aatgtccgtg cctattattt agaatacgat agtgaacgtg ctgggagttt
      301 tgttctttta gagaaagtct ctgaagataa attagttgtc ttagattttg actgtaacga
      361 aaaatggcga aatggaagag caccagcaag tgattgaccg gatctacgaa gcgacacgat
      421 atctgccttt ggatcgtttg tgcttaagtc ctcaatgtgg atttgcttca acagaagaag
      481 aaaatgtttt gtttgaagaa caatggaaaa aatttctttt gtcaaaagca ttgcagaaga
      541 agtttgggga aaatcattaa atcatctagg agagcttgat aggaaataac actatggtat
      601 aatcagaatg cttaatacta actactgagg gagccttatg aaaaagaaaa ttcttaaatt
      661 tatcggatgg ttcttcggaa tcattcttgg gatcgcgttt gcaatctttc ttgccttcca
      721 gctttccccc agacctggag cattcttgat caaccatatg ttttcaaata ctgttcaaat
      781 cactgataaa aaaacgttcg atcaagcaga aaaaaacgtg gcgaaaaaaa cagatttgac
      841 gtatgagtcc aagtataaag agaatactta tgacatctac tatccaaaaa acagcaaggg
      901 gcctgttcct gttctatttt gggtacatgg tggaggattc gtcggcggag ataaatcggg
      961 tgtcaaagaa tttgcgacaa aattagtttc agacgccaac atcgcagtgg ttgcgatgaa
     1021 ttatgaatta gcgcctgatt cagaataccc taatcaagtt cttcaagtga atgaactgat
     1081 caaagattta ttagctgaag aaaaagacga caaattgcta gacatggaac aattattttt
     1141 tggtggagat agtgcaggtt cacaaatcgc attgcaatat gcagctatac aaacgaatga
     1201 tgcgtatgct aaacaaatga aaatcaaaca gctacttcca aaagatagtc tgaaaggaac
     1261 catttcttat tgcggacctg ttgatttgaa gctaacagca cagcagcatt cggatgatcg
     1321 atttatgaag tttttcgtca aaaccgttgc gtggtcgttg attggaacaa aagattggaa
     1381 aacgagtgag caattgaaag aagctagtgt ggctgaccat gtttctaagg aatttccgcc
     1441 aacgtatata actgacggaa atgcatactc attccaggag caaggtcaag cattagaaaa
     1501 tcggttgaca gaattaaagg tacccgtgca atccttgttt tatacagata caaaaaaaga
     1561 gattacccat gaataccaat ttgattacac gctaaaagaa tcgcaaaatt gttaccagca
     1621 gacattggat tttgtgaata agtataagta agaggttgtg aaaaagccgt ttcgttttga
     1681 gtatgaagaa acgaagcggc ttttcacaac ctctctttca ataccttttt gttcttggga
     1741 taaaactttc cctaacaatc aatcgtgcag gataagtcaa aatgattggt tcgtcccgta
     1801 taccgtcaat tcgctccaat gccattcgaa cagctgcttg cccaattgat ttcgcattga
     1861 tttgaacact ggtcaagcca ggggagaggt ttgcgattgt ctcgatatta tcaaagcttg
     1921 ctacaacaat ctcttctcca atttggatat ttttttgttt caatgcccga tagacaccaa
     1981 ttgccattgg atcgctcccg acaagaatgg cagtaggaag aggggattca ttttctaata
     2041 gattagtcgc aagtacctca ccttgttttt ctgtccagcc acctagatga taagacatat
     2101 atttttctaa gtgatgatcg atcataaaat gctgataggc acgcatcctc ttttcattta
     2161 tagaaatctg cttcccaccg aattcatcca tatcgacttt atatcccccg atataggcta
     2221 ttcttttatg accattttct aagaacaatt ccagtacggt tttagtcatc cgttcaagat
     2281 ctgcatacac catatcgacc tcttgctgga tgtcagggtt atccacgacg actatttgca
     2341 tgttttgttt taacaaggcg gtaatcgatt ctttcgtaac agtcccaaca acgatcaccg
     2401 cacctaactg atctagatct tcccattgtt taggattatc agatagatta tagattcgat
     2461 tcatccctaa atgcagacgt cgagcttctt cttccatccc tactcgcaaa tgtttgtaat
     2521 agatatcctg ttcttcgctc gctttgccga tcgtagagat cacaccaatc gaaggcattc
     2581 tctttttgat atatttacga gtactgatgt cataatccaa cgcagcagct gcctctacta
     2641 tccgttgccg agtagtctga gccacatgga tcgtctgatc gttattcaac acacgggaaa
     2701 ctgtagcagg agagacattt gcctttcgtg cgacatctct aattccaacc atttttacac
     2761 actcctcaaa aaaataaaaa atttttattg acaaaattgt ttagtaaaca gtatacagga
     2821 attataaaaa aaagtaaacg gtttccgttt tgttgggagt gaaatgatgg atattacgca
     2881 tagaaaaaca gataaaaatt tcatcttatt tgatgaaaag agccgagtct tccatttacg
     2941 aaatacattt ctttcttatc tgataaagat agaagaaagc aatgtattgg cgcatattta
     3001 ttttggcaaa ccagtcaagc agtacaaaga caataaaaat tatccccgaa gagatcgtgg
     3061 attttcagga aatgttccct taaatcctga ccggtctctg tcgaaagata cactaccgca
     3121 agaatactct tctcatggca gcatggactt tcgaacgccc gcatcgatca ttcagcgcaa
     3181 gaatggatca gacttactgg atctgagata tgacagccat tatattacag atgggaagcc
     3241 agagatcgaa ggcttgcctc aaacttatgt gatggacaag tcagaggcac aaacgttggt
     3301 gatttcactt aaggatagag aaacagcgat ttatttcgat ttgttctata ccatatttac
     3361 tgatagagca gtgatcacac gatctgtaaa gataagaaat gaaaccggag aaacaatcaa
     3421 actagaaaaa gcggctagtt tccagctaga ctttgcccat actaggcgat ttgatgaagt
     3481 cattgctttg ccaggagcac atgtcaatga aagacagatt tcacggcaat ctgttttatc
     3541 tggaacaaaa gtatttgaaa gccgtcgagg aacgagcagt caccatatga ataactttat
     3601 tgctttagtt catcatcata cgacagaaaa tactggagaa gcgatcggac ttcaatttgt
     3661 ttattccggc aaccattctt tcgaacttga aaaagatcag atcaatcaat tgagagtcgt
     3721 cggtgggatc aacagccatc gtttttcgtg ggaattgaat gcaggccagt cttttcaaac
     3781 acctgaaatg atcctttctt actcaagtca gggattgaac aaaatgagtc agatccacca
     3841 tgagttgcta cgtgaaagaa tcgcaagagg tcgtcatcaa tttgctgaac ggccgattct
     3901 ggtcaataac tgggaagcca cttactttga cttcaatagt gaaaaaatca aggcgatcat
     3961 tgatgaagca aaggagctag gcatcgaaat gttcgtatta gatgatggct ggtttggaaa
     4021 aagagatgcg gacaattctt cattaggaga ctggttcgag tatgaaggca agttgacaaa
     4081 tggattacgt gaaatagcag attatgctca tagcaaagga ttgaaatttg gtttatggtt
     4141 tgaacctgaa atgatctcgg ttgattctga actgtatcga acacatcctg attttcttat
     4201 gcaggagcca ggtagaatgc cttctgcttc cagatcacaa catgtactgg attttacaag
     4261 gttagatgtt cggcagacga ttgagaaaca aatgagaaag attttagata cgattcctct
     4321 tgactacatc aaatgggata tgaaccgttc gctttcagat gtctattcga ttacccttga
     4381 cccacagaga caaggagaag tagcgcatcg ttatatgctc gggctttatg aactacttga
     4441 acatttgaca actgattatc cggaaatctt atgggaaggc tgttctggtg gaggtggacg
     4501 gtttgatgcc gggtttattt attatatgcc gcagtcatgg acaagtgata acacggatgc
     4561 agtggagcgt atgaaaatcc aatatggaac aagccttgct tatccgattt cgtccatcac
     4621 agctcatgta tcagctgtac caaatcatca gaccgacaga tctacttcgt tgaaaacaag
     4681 aggagaaaca gctatgagcg ctgtttttgg ttatgaactg gatttgacaa agctgtctcc
     4741 tgaagaaaaa aagcaagtaa aagaccaaat tatatcctat caaacgattc gtccggtgat
     4801 ccagtatggc cattattatc gtttggcgag tccttttgaa gaaaatattg ccgcatggat
     4861 gtttgtgtct cctaaacaag atgaagctat tgtgttttta gggaggatac tagcttcagc
     4921 tcaaccagcg ttccatgaag tatatctgat ggggttagat gatgaggcac tttatcagga
     4981 acagacctcg aagcggatat tttcgggggc cgaattgatg acagttggac tttacttccc
     5041 cgattttcaa ggtgatttcc aaacagaact gcttcatttc aaaaagttat gagagagaag
     5101 gaaaaaagta tgaaagcaaa tataaaatgg ttagatgatc cacaagtttt tagagtgaac
     5161 caatcaaatg cacatagcga tcatgtttgt tatgcaacaa gggaagaagt agaaaccaca
     5221 tcctccctta aacagtcttt aaatggatca tggcgttttt gttattcgcc aaatccttcg
     5281 gtacgaccaa aaacatttta taaaaaagat tttgatgcct gttcttttga tgaaatcact
     5341 gttcctagtc atattgaatt agcaaattat gacaagatcc attacatcaa tacgatgtat
     5401 ccgtgggagg gacatgtatt tcgccgtccc cctttcacga caagccctga gaaagaggcg
     5461 gaagggatct tttcagctgc taaagacaat ccggttggtt cgtatttgac gacttttcga
     5521 ttagaagaag gtctaaaggg aaaacaaatc tcgattcatt ttgctggtgt agaacaagca
     5581 atgtttattt ggttgaatgg tcattttatc gggtatgccg aagattcgtt cactccgtct
     5641 gaatttgatt taacacctta tttggaagaa gaaaatattc tagctgtgga ggtttacaaa
     5701 agaagtacag ctgcattctt ggaagatcag gactttttcc gattttttgg gatcttcaga
     5761 gatgtcttct tagttgctcg aggacaaaac catttagaag atctttggat caaacctcgc
     5821 ttagatgaca aatgtcaaaa tggcaaactt gaagtagatt tgtcttttga gcaagtagcc
     5881 aaaaacagtc agctgaatgt agcgatacta gatcctgatg ggaaggaaat ctatcaacag
     5941 caatatccgt taaaagagca aatgacgatt cgcatcgatg gatttgaaaa tgtggcactg
     6001 tgggggcatt ttcagcccaa tttatataag cttgaattgg agacgataga cgaagaaaaa
     6061 agagtaacgg agtatattga ctattccttc ggttttcgta aaatcgaaat caaagataaa
     6121 atcatctact tcaatggaaa acggatgatt atcaacgggg taaatcgaca tgagtggcat
     6181 ccgaaaaaag gacgcgccat cactatagaa gatatggaaa aagatttggc tatcataaaa
     6241 aatgcaaaga tcaacggcgt acggacatct cattacccca accagatcac ttggtattat
     6301 ttatgcgacc aagcaggaat ccatgtgatg gcggaaacga acctcgaatc ccatggctca
     6361 tggcaaaaaa tgggcgcatt tgagccttct tacaacgtac caggtgcagt acctcagtgg
     6421 caggcggctg ttcttgatcg agcaaaaacg aatttcgaaa cattaaaaaa ccatccaagt
     6481 attctttttt ggtctcttgg aaatgaatct tatgcggaag aaaacattcg acaaatgaac
     6541 gattacttca aaaaagtaga ccccgatcga cttgtccatt atgaagggaa ttttccaaat
     6601 ccagcattcg aagattcgat ttcagatgta aaaagctgca tgtatgcgcc accagaagag
     6661 atcattgact accttgaaaa taaagcggaa aaaccgttca tcttatgtga atatatgcat
     6721 gacatgggga attcgttagg tggaatggat tcttacatga cgttgcttga tcgttatgaa
     6781 atgtaccaag gaggctatat atgggatttt aaagatcagg cgatccaagt gactgatcca
     6841 atcacaggca gagaagtgat gcgctatggc ggtgactttg acgataaacc aagtgactat
     6901 gaattctcag ggaatgggat cgtttttgca gatggacaag aaaaacccgc catgcaggag
     6961 gtaagatatt attatgaaaa atacagtaaa taaaagtcat atggatacgg aaaaagttgc
     7021 aatcgtcttc ggcgactgta cattaggtgt caaatcgggg aatacgcatt atattttttc
     7081 ttatacaaga ggcggactgg aatcgctcaa taaaaacgga aaagaatggc tataccggga
     7141 aacacttcca gttttttggc gagcaacgac cgataatgac agaggtagcg gatttggatt
     7201 taaatccggt atgtggttag gagccggatt gtatccaaaa gtcaaagaaa tagaagtact
     7261 ggtggacaat aaaaagatcg atttgccgat tgctccagta aataatcaat attcaagtaa
     7321 tgaatacgct gaaacggttg aaatcatttt tacactggaa atcaacacag taccaaaaac
     7381 ccaagtgaca atttcctacc aaatcgctgg agagggtaaa atgcttgtca atatgcatta
     7441 ttatggacaa aaaggattac cggaattacc cgcattgggt ttaaggttca ttatgccaac
     7501 gaaagcaaaa ttttttgagt atgaaggcct atcaggggaa acatatccgg atcggatggc
     7561 tggtggtgtc gaaggtattt ataaagtggc aggactcccc gtttccccat accttgttcc
     7621 ccaagaatgc ggcatgcata tggaaacgaa atgggtagaa ctaacaagaa atcaaacgtt
     7681 ggataatacg gataaagatc aagaagattt ttcgttgcga tttgaacagc aggatacgcc
     7741 atttgctttt tccgctttac cattcaaagc agaagaactg gaacaggcaa cacatataga
     7801 agaactaccg ccagaaagac gaacggttct tacgattttt gcaaaagtaa gaggagtcgg
     7861 gggtatcaat agctggggag cggatgttga gtcaccttac cgaatcagca gcgaagagga
     7921 ccatgaaatc ggctttatta ttcagtagca atctttagat tattatttga aaaacggagt
     7981 ttacaagaca aagctgcttt attctatatg tcatgaacaa gagagtaaaa aagttctcag
     8041 atacttttgt tcatgactat tttcttcaat aaaaccaatt gttatttttc tgaaaaacaa
     8101 agttaactat cagaaaatta aaaaaagttt cataaaaatg attgacagtc gattttttta
     8161 tgtctatact aggtacaatt cttacatcag tttggagcga ttttttatga aatctagaaa
     8221 acttacaaaa ctgaatacgt attactttag ctattttaga taggtttgta ttcatgactt
     8281 cgtgggtaca aacaaaccag gtttgtatct atgatggcta aagattttta aacacgactt
     8341 acagccacgt agagaaattc atctatagtg gctattttat atttttgcag cgctttttaa
     8401 ggctcgttga agatgttcac tgtagaggca atttcctaca gggacatctt tttttgttga
     8461 ttatctgggt cataagtagg aaagaaggag cgaaaatgag aacaacagga cacggtcatt
     8521 tagtaggaat taatgtaaaa ccaccttgaa aaagtagaga aaatcagcca agatagataa
     8581 gtaaacaaaa gaaagcggga aaaacaatga tagtaattat gaaaaaagaa gcaacggaag
     8641 aacaaataaa aaaagtcgtc gatcatatcg aaaaagaagg attcaaagtc tcaatcgatc
     8701 aaggaacaga acgagtagtg attggactaa aaggtgatac gcgaagttta caagaaggag
     8761 catttacacg ctatgaagga gtagaaaatg ctgtgcgtat tttaaacaca tacaaattga
     8821 cttctcgaga attccatcct ggcaatacag tcgtggatgt agacggagta aaaattggtg
     8881 acggcagttt cgtgacgatg gctggtcctt gttctatcga aggattagac caaatcagag
     8941 aatgtgcgcg aatggccaaa gccgggggcg caaaaattct gcgaggtggt gccttcaaac
     9001 cacgtacttc tccatatgct ttccaaggtt tagaagaaga aggattgaaa tacatccgtc
     9061 aagcggctga tgaatttgga atgaaagtga ttactgaagt gatggatgaa gggcatatcg
     9121 atatggtggc tgagtacagc gatatcctac agattggcgc acgtaatatg caaaatttta
     9181 aactgctatc tgctgtcggt aaaacaggta aacctgttgg attgaaacgt ggaatttccg
     9241 gtacgatcaa tgaatggctt aatgctgcag aatacattgc agtcgaagac aaatctcctg
     9301 tcatttttat cgaacgtggg attcggactt acgaaacagc gacacgtaat acgtttgatt
     9361 taagtgctgt cccattgatg aaaaaattaa ctcatttccc tgtgattgtt gatccaagtc
     9421 atggtacagg aatttgggaa cttgtaccac caatggctcg tgcgggtgtg gcaagcggag
     9481 cagatggcat gatcgtagag atccatcctg atcctgcaaa tgcttggtca gacggtcccc
     9541 aatcgttgaa tgaaaagact tactcacgca tgatgaaaga agttgcgatc atgaaagaag
     9601 caatggaaaa gattcagaca ctcgattaat tccagctttt taaaagaaag aagtgaaacg
     9661 aatgcttact gtacatgttg ataaccaaaa atacgatatt catattgaaa aaggcgcact
     9721 agaacaggct ggatcatggc ttcaaacgat ttggagacct caaaaagtag ctgtgatcac
     9781 tgatacaaac gttgctccac tatatgcaga aaaaatcatg ttccaattga gacaagctaa
     9841 ttttgaacca gtcctttcaa tcgtaccggc gggtgagacc agtaaatctt tagaacaagc
     9901 agctgagtta tacgattttt tagcagataa tgattttacc cgcagcgatg ggatacttgc
     9961 acttggtgga ggaatggtgg gtgatctagc agcattcgtg gcctcgacgt tcatgcgtgg
    10021 gatccatttc gttcaaattc cgactacgct acttgcacaa gtagattcta gtattggcgg
    10081 gaagacagca gtcaatacaa acaaagcgaa aaaccttgtc ggaacattta gccagccagc
    10141 tggtgtattg attgatcctg aggttctaaa aactttgccg gtacgtcgtt tacgagaagg
    10201 aatcgctgaa atcatcaaat cagcagctat agcagatgca acgctttgga aacagctgaa
    10261 cgagctgaaa gacgaaaaag atcttctgga acatgctgtt ccaatcatta ctgctacgtt
    10321 ggaaatcaaa cgaaaagtag tggaagaaga tgtctttgac caaggaaatc gacttatttt
    10381 aaattttggt catacaattg gccatgcaat tgaaaataca gcaggatatg gggtagtcag
    10441 tcatggagaa ggagtagcta ttggaatggt agccatcact tctcatgcag aaaaaatcgg
    10501 cttgtctcca actggatcga cagctgcttt agaaaggata cttcaaaaat tccatctgcc
    10561 gattacgtac gatctaagtc atccagatga attattccac gcgataaccc atgataagaa
    10621 agcaagagga agccaattga atatcatctt gctagaaaag attgggcaag caaaaatcgt
    10681 tcctgttccc acagagacat tcaaagatta cttaggagga ctgtaagatg cgttatatga
    10741 ctgcgggaga atcccatgga ccagaattaa cagccattat tgaaggacta ccagcaggat
    10801 tacctctgtc agaagaagaa atcaatcacg aactcgctcg cagacaagct ggttacggca
    10861 gaggaggaag gatgaagatc gaaaaagatc gtgttcggat cacgtctggc atccgtcacg
    10921 gcaaaacaat tggttcacct gtcactttag tggtagaaaa taaagattgg aaaaattgga
    10981 caactgtcat gtctgtagca gaagtgcctg aaaaagacca atcactgcgg cgagttgcac
    11041 gtccgcgtcc aggacacgcg gatttggtag gcggtatgaa ataccatcat cgagatcttc
    11101 ggaatgtgct tgaacggtcc tctgcaagag agacgaccat gcgtgtagca atcggcgcaa
    11161 ttgccaagaa aattctggaa gaacttgaca tcatcgtagc aggacacgtg atttgtcttg
    11221 gtggaatcca agcagaaata cctggaaata tctcgattca agaaatcaaa gaaatttctg
    11281 aagcgtcaga agtacgagtt gttgatccag cagttgagca aagaataaaa gatttgatcg
    11341 atcagacaaa gaaaaatgga gatacgatcg gaggaattgt agaagtgctc gttggaggcg
    11401 ttccagctgg attaggaagc tacgtacaat gggacacgaa gctagatgcc aaaatcgcac
    11461 aagctgtggt tagtatcaat gcctttaaag gcgtagaatt tggggtcgga ttcacttctg
    11521 gttcattacc aggctcagaa gtgatggatg agatcctatg ggaagaagaa agaggctatt
    11581 tccgacgtac caataatcta ggcggcttcg aaggcggaat gaccaatggc gaaccacttg
    11641 tcattcgcgg ggtcatgaaa cccattccta cattgtacaa gccacttcaa agtgttgata
    11701 tcgatacaaa agaaccttac aaagcaagtg tagaacgttc ggatagtaca gcagttcctg
    11761 cagctagcgt cgttgcggaa aatgttgtag ccactgtggt agcgacagag ctattgtcaa
    11821 aattcccaag tgattcgctt gttgagttga aagctgcagt gaaggagtac cgtgactact
    11881 tgaaacatta ctaaaaaggg ggcaaataag atggcacaac atgtttttat cgtggggctt
    11941 ggactgattg gtgcttctat ggcactttgt attcgtcaga ccaatccaga actgatagta
    12001 gttggttggg atagtcagtc aaaaacccgt gagcaagcag tagaacagca gatcgttgat
    12061 tacgttgcaa gtgattttga aacaggtgca gaacaagcag acgttatctt attagccgtt
    12121 cccgtccgta caaccttagc ttatcttgat gtccttgaaa gaatcaactt gtctgatcac
    12181 gtcatcatta cggatgtcag cagtacgaag cagcaagtcg tgacatccgc tgagcagaaa
    12241 aatcttcggt ttgtcggtgg acatccaatg gctggttctc ataaatcagg tatacaggca
    12301 gcagatgcta aactatttga aaatgcctat tacatcttta cacctttgga aaagacgaaa
    12361 aaagatgttg aaaaactgca agaactattt tgcggaacca aagcaaaata tgtaactctt
    12421 acagcaagag aacatgaccg tataacagga atgctaagtc attttccaca tattctggca
    12481 gctggcttag tcaatcaggc agaacaattc aatcaagagt atccgcgagc caaacaactg
    12541 gcagcaggag gctttcgaga tatcactagg atcgcttcct cagatcctgt catgtggaca
    12601 gatattttgt tgagcaataa gcagatatta ttggaacgat tggcagattg gcaacaagaa
    12661 atgacacaaa tagcagaatg gatcatgact gagaaccaat cggaaatctt ttcttttttc
    12721 aatcgggcaa aagaaagtcg agaccagttg cctgtccata agcaaggcgc gattcctgcc
    12781 ttttttgatt tatttatcga tgtgccagat gaacctggcg ttattgcaga agtaactgga
    12841 ctgatcggaa aagcgggagt ttctttgatt aatttgaaga tccaagagac cagggaagat
    12901 attttaggaa tactgcaaat cagttttaaa aaccaacagg atttgttaca agcaaaaaga
    12961 atcattatgt ctaataccag ttatcattgc tggatcaaat aggaggctgg ataaatgcaa
    13021 ttattacaac aaatacatgg attaagaggg actgttagga taccagcaga taaatcaatt
    13081 tcccatcgca gcatcatgtt tggagcaatt gctgaaggaa cgacgactat acaaaatttt
    13141 ttgcgcgcag aagattgtct gagtacttta catgccttcc aacaattagg tgtcgagatc
    13201 gaagaagagg aagaggtgat caagattcat ggtcgcggta gccactcatt tgtccaacca
    13261 accgaatcaa ttgacatggg aaactccggt acgaccatac gtttattgat gggtattttg
    13321 gctggacagc cttttacgac tactctgttc ggggatgctt cgttgtctaa acgtccaatg
    13381 gggcgagtga tggaaccttt acgcgagatg ggcgctgact tgcaaggaga agaaaatgac
    13441 cagtatctac caatcactgt gacaggaacc cgctctttat cacctatccg atacaatatg
    13501 cctgtagcca gtgcgcaagt caaatctgct ttgctgtttg cggcattaca agcagaaggc
    13561 acatccgtaa tcgttgaaaa agaacgttcc cgtaaccata cggaagaaat gattcgtcaa
    13621 tttggcggaa ggatcacagt ggaagataaa acgatcatag tgaccggacc gcaaaaatta
    13681 actggtcaac agataactgt tccaggtgat atttcatcag ctgctttctt tctagcagca
    13741 ggacttcttg ttccggaaag ccaactgttg ttaaaaaatg tcggggtcaa tccaacaaga
    13801 actggtatct tagatgtgtt ggaggagatg ggcgcagcga ttacccagac gaatcacaat
    13861 gaacagaacc aatcggctga tttaagtgtc aagacgagtc atttgaagaa agcaacgatt
    13921 ggtggagaaa tcattccgcg tctgattgat gaattgccca ttctagcttt agtggctact
    13981 caagcagaag gaatcacgat catcaaagac gcagaagaat taaaagtaaa agaaaccaac
    14041 agaattgatg cggtggcaga agaattacag aaaatgggag caaagataaa agcgacagca
    14101 gacggtctga tcatccatgg gccgacacct ctgcatggcg caaaagtgtc cagcagaggc
    14161 gatcatcgaa tcggtatgat gctgcaagta gctgctttga tagctgatgg accttgcgaa
    14221 ctagaaggag ctgaagctgt ttcaatctct tatccggcat tttttgacga tttagcagaa
    14281 cttgtgtcag gaggagaagc tcatggctag cattttgctg attggtttca tgggcgctgg
    14341 aaaaacaaca atcggtaaag ggttagctca atgtttacaa aaagagtatg tagatttaga
    14401 tacaaagatt gaggaacata tccaattgtc gattgccgaa tattttcact attacggtga
    14461 aaaaagcttt cgaaaagtgg agtcagat
//
LOCUS       DAZAOD010000065        14344 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000065 DAZAOD010000000
VERSION     DAZAOD010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.066"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(520..1704)
                     /locus_tag="ACHDPO_001961"
     CDS             complement(520..1704)
                     /locus_tag="ACHDPO_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFN3369576.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(1729..2736)
                     /locus_tag="ACHDPO_001962"
     CDS             complement(1729..2736)
                     /locus_tag="ACHDPO_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFN3369577.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(2908..3267)
                     /gene="comGG"
                     /locus_tag="ACHDPO_001963"
     CDS             complement(2908..3267)
                     /gene="comGG"
                     /locus_tag="ACHDPO_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFN3369578.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(3239..3664)
                     /gene="comGF"
                     /locus_tag="ACHDPO_001964"
     CDS             complement(3239..3664)
                     /gene="comGF"
                     /locus_tag="ACHDPO_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFN3369579.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            complement(3627..3974)
                     /locus_tag="ACHDPO_001965"
     CDS             complement(3627..3974)
                     /locus_tag="ACHDPO_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369580.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            complement(3946..4416)
                     /gene="comGD"
                     /locus_tag="ACHDPO_001966"
     CDS             complement(3946..4416)
                     /gene="comGD"
                     /locus_tag="ACHDPO_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFN3369581.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(4391..4669)
                     /gene="comGC"
                     /locus_tag="ACHDPO_001967"
     CDS             complement(4391..4669)
                     /gene="comGC"
                     /locus_tag="ACHDPO_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFN3369582.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(4666..5715)
                     /gene="comGB"
                     /locus_tag="ACHDPO_001968"
     CDS             complement(4666..5715)
                     /gene="comGB"
                     /locus_tag="ACHDPO_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFN3369583.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(5672..6601)
                     /gene="comGA"
                     /locus_tag="ACHDPO_001969"
     CDS             complement(5672..6601)
                     /gene="comGA"
                     /locus_tag="ACHDPO_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFN3369584.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            6733..8487
                     /gene="ade"
                     /locus_tag="ACHDPO_001970"
     CDS             6733..8487
                     /gene="ade"
                     /locus_tag="ACHDPO_001970"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFN3369585.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(8585..9247)
                     /gene="trmB"
                     /locus_tag="ACHDPO_001971"
     CDS             complement(8585..9247)
                     /gene="trmB"
                     /locus_tag="ACHDPO_001971"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFN3369586.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(9317..10099)
                     /locus_tag="ACHDPO_001972"
     CDS             complement(9317..10099)
                     /locus_tag="ACHDPO_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFN3369587.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(10303..11514)
                     /locus_tag="ACHDPO_001973"
     CDS             complement(10303..11514)
                     /locus_tag="ACHDPO_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369588.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(11507..12244)
                     /locus_tag="ACHDPO_001974"
     CDS             complement(11507..12244)
                     /locus_tag="ACHDPO_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369589.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            12382..12816
                     /locus_tag="ACHDPO_001975"
     CDS             12382..12816
                     /locus_tag="ACHDPO_001975"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFN3369590.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            12809..13153
                     /locus_tag="ACHDPO_001976"
     CDS             12809..13153
                     /locus_tag="ACHDPO_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFN3369591.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            13333..14343
                     /locus_tag="ACHDPO_001977"
     CDS             13333..14343
                     /locus_tag="ACHDPO_001977"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFN3369592.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
BASE COUNT         4566 a         2924 c         2416 g         4438 t
ORIGIN      
        1 gagtctcttt ttgagttgaa acgaagaaaa aagtgttagt agaaaatcgc tttcgatttt
       61 ccaccaacac aaaatattat agaaccgttt tttcgcaaca aaaaacttga ttttcatacc
      121 tgtgctttca cgattcaggc aaagtacagg tggaaaatca agtttttatt attcgatcaa
      181 tgaatgtttc ggatcggttt tctagctaaa cataaagcga agaataaagt cgacagccca
      241 cgaggctgat ctaaaaatgt tttttctttt tacatatgta atgtccctta taaagatgaa
      301 tgaaaataaa atattgggat tttcctgaaa atcaataaat aaaatgccag tcttttccct
      361 tttgaccact tttccaagca aaattcccta agaagatcct gtaaaaaaga agggaaattg
      421 aagttaaatt accattttgc ggtcttctcc gcaaaaaaaa cacatgcaag aattccctct
      481 tgcatgcgtt tcatctttta tcctaacgaa tgctttggct tagccgcgca gacgctccac
      541 atcacgggca atcattagtt cctcatctgt tgggatcact aatactctta cttttgattc
      601 ttttgtagag atatctactt cttcaccacg caattcattc aacgctggat cgatttcaca
      661 accaaaccaa gacatacctt tgatgatttc actacgtaca tgtccgtcat tctcgccgat
      721 accagcagta aagacaattg catcaacacc attcatcgtt gtcacataac cgccgatgta
      781 ttttcggatg cggtccacga aaatgtcata agctaaacga atatgttctt tttcatagtt
      841 cttttcaaga tcacgcatat cactagacaa tcctgttagg cctagcagac cagatttctt
      901 gttcaaaaca ttgatcattt catcaatatc aatctctaat ttttccatta aatatgggag
      961 aacagctgga tcgatatcac ctgaacgtgt acccattgtc accccagcta atggtgtgaa
     1021 tcccatagaa gtatccatgg atttacctcc atcgactgct gtgatcgata caccatttcc
     1081 taagtggcaa gtgatgattt ttagttcttc gatcggtttg ttcaataatt ttgccgcacg
     1141 ttccgacaca taacgatgac ttgtgccatg gaagccatat tttcttactt tgaaatcttc
     1201 ataataagac accggtaagc tatataaata attttgcttt ggcattgttg agtggaaaga
     1261 tgtatcgaat acagccacac tcaaaatgtc aggtaaaatc tttttaaacg ctttgatccc
     1321 cattaagttt gcaggattat gcaaaggagc aaattctgct aattcagcaa tgcggtccat
     1381 tactttctca tcgatcacta ctgaatcccc ataagtttct cctccgtgaa caacacggtg
     1441 ccctactccg gtgatttcat cataagagct taaaatttgc agttcaatca actgatctaa
     1501 cagcattttt actgctactt cgtggttttc gatatccatg atttgttcga atttttgatt
     1561 atcgccgtac ttgatggtaa aaatagaatc ttgtaaaccg atacgttcga cgatcccttt
     1621 cgcaactacg gtttcttctg gcatttgata taattgccat ttcaaacttg aactcccagc
     1681 attgattgca attgttttag acatatgact ctccttctcg ttgaatgatt acagagcaga
     1741 tgatttccag tttttaaact cgttgaaaaa ttccgtcacc ttctctggtt cttttaatga
     1801 agcaagtttc acaagcaaga cttcttttac ttgttgtgct tgtggtcctt ttttctgtaa
     1861 gatcaaaata cttttttgcg attgtttatt acggaacaat tcatctggca attgaatcat
     1921 tccttgaaga taaccttctt ctttaaacca ttttttgatt tcttcacttt gatccgtttc
     1981 taaaaatcca ctcggcatca aaaacaaacc aaaaccatcc ggcttcacat atttcattga
     2041 ttgctctagc aataaatgat gtgcataact atggccttct tcggtacttg ttaaaaactc
     2101 ttttgctttt tcgtcattcg gataataacc gattggcaaa tcgctgattg caaaatcgac
     2161 aggatctatt aataattcct gcaacccgtc ttgatgaaag tattgaacat ttgcttgtgt
     2221 caaatcactt gtagaagctg cgacagccaa caatgtatca tcaatatcca caccaattcc
     2281 ttctgtttgg taccccgcat tcgataggtt taaaagaact gttaataaca agttgcccat
     2341 tcctgccgca atatccagaa tcttaaccgg tgctttttta tttgtgtata gttgttcaat
     2401 aagaaaaaca aataaaaaac cgatactatc aggagtgagt tgatggttcg cctgcaaatg
     2461 ttctgtctgg ctgcccttca ataaaagtaa ttgagacagt ctgcgccatt cttctggctc
     2521 gaaagaaagt ttcttcaact cttcataaag agctgtgatc cgttgcgttg tctcttttgt
     2581 cggcactcca tccaccacac gtacttgata atcatctatt aaattttctg cattttcgac
     2641 ataggcttct aaaaaggaag ttcccaatgc attctgtaaa agctgaatag cttccaggtt
     2701 ttgattaaac ccttgttcca ttttttctgg taacatggtg cacctcattt ctagatatat
     2761 tataacaatt ttttcacctg tttaattcta tcgaacaatt gacaaaattt caatcgtttt
     2821 cactgttttt tatttgtgaa acggcaaaca tttttttatt aaaaacagtg ttataacaga
     2881 aaagagggcg ttttcacgaa cattccatca ttctgtacta gtatctgtat cattttttac
     2941 ttcttctgtg aaccgaaaga taaacggtga gacttccacc tctaagaata gggactgttg
     3001 tacccactga tatgttacag atccagttgt gtagtaaaaa actccttccg aactttcggc
     3061 aagcgtagac tgttccgata aagccatctg cttcattatt tttgctatat aataattttt
     3121 gattcgtata ttaagatcca ttgacaaacg gtagctttct aatgctgcca tcaataaaaa
     3181 cgtacataaa agaaataaaa gcaagacaga aaataaaata gagcccttat aacattttct
     3241 actgatcgtt ttttgtccat atggcatatc catcttctcc attttcaaag tgtacataaa
     3301 aagaaattgt gtgttctttt tccaataatt gaagctcagt gatacttgtt aacataggtt
     3361 gatgtccgcc ggaagttctt cttttacgta tcattgcctg atatctttcg atgatatact
     3421 gtttatcctc gatcgtgtag tgcagttgct gatttttcac agagacattg tgactgctct
     3481 tgagttcttc ttctaattgt gctaaaaata ttagccactc tttttgatct ttacgctgca
     3541 aaaattcact tacttggatg gtttgctgaa tcaaaagatt gaatgtgagc aatagactgc
     3601 tcaatatcat cagtccaatt agacattcaa tcagcgtaaa tgctggaatt acttgttttt
     3661 tcaatactga tcgcttcttt ctccatattg acaaacactt tttcgattac tccattatta
     3721 tcgacaattt ggatatcgta tgggatcatt tcttcccttc gctctggtct tttgtgatac
     3781 atccgctgcg tcttgatatc ttcataaatc attcgaataa atagcagttc ctccccactt
     3841 ttcttttctg cctgaagcaa aaacagctgg ccaaagctca ctaagtagac acagacagaa
     3901 gcgatcataa gcgctgtaag ggactccaac aaaacaaatc ctgttttatt caattctttt
     3961 tgtatagcga ccactcccta tctggaattg atacgtaatc gtccgctctt tttcttccca
     4021 ataaaattga taagctttta gtgaactttc attcccggtt ctagcagcaa aagtaataga
     4081 agcatggcgt ttcaaggtaa tctcatcagg aatatctaat acttcccaat ttattttatc
     4141 tggattcgga acatgaaaaa tgatttgatt ctcttcacta ttccaataaa agcctgtttg
     4201 gatctgattc acaatagcga ttttttgcgt agaatagatt cgtttttcaa attggccgaa
     4261 aaattgatag actgccaatt cattcttcca tgcagaaaat gcgagaactg gaaaagaaag
     4321 gatcgttgta agtaataaaa tcagtaagag tgattcaaac aacgtatatc ctgatgctaa
     4381 aaccttacct tcaaggccgc tgatagattt ctgcatgttc tcgtttgata tagccttcat
     4441 tcaacaattc ctccacagta ggaactcttc cattattttg aagcgcatag agctcttttt
     4501 gtgtgtctac caactggatg atcgcttcac gactttcttg gtctacatga ttcctataac
     4561 gcgacaaatt agggacgaac aacaacacta atacactgat gatcagtaag acgattagca
     4621 tttcgatcaa tgtaaaaccg ctataataag atatttttct ctttttcatg gcaaaacctc
     4681 ctctatgctt ccgtaaacag gtaataaaac agcggcataa actaataaaa tcaaagccgc
     4741 tacgcccaaa aaaatgattg gctgaataaa atgcatccag tgatgaagac gtttgaaaag
     4801 ctgttttctt gtccattcgc tgtaaaaaat cagttcttta cctaaacttc cctttgcctc
     4861 tccctgtaaa acaattttac tgaattcttc tgatagaaaa cgataattct ggaactgctc
     4921 agccaatgac atacctgcct ccaatccttg aatcaactta gaggcaagat gctgaatcag
     4981 actttcttgt ttcgtttcct ttaagcagac tatgatttgc cttaattcga aaccttcatg
     5041 aaaaagcttt ccaatctcta gtgacaaata agccgattga tacaaggaat atatcggtcc
     5101 aatcaataat tgtctgctta tccattcact ctgatcaaca ggagacaact tcatcagacg
     5161 ataccttact agtaaagcca atagagtaac cgctaggatg aatagtagaa cataccaatg
     5221 aaagacttgt atcagctgaa taccccaatg ctcttgcatg accattcctg aaccaataag
     5281 ctgaggcaaa acgaacaacc gcatactaaa caagatacct agcaaaaagg tgagcaatag
     5341 catcggatat gcaagcagct ttttcaaatc attgcgaaat ccttcaacaa gccgaaactg
     5401 tttggcaatt tccaacaaag ttgtcggcag attcccatga cgttcagcta actcgatctg
     5461 taccagttgc tctgctccat atcctatttg cgaaagtacc tcactaaacg cttgcccttc
     5521 ctttagctga tgttggatat ttgccaaaat aacaggtgga aacgaacgga tcgtgagtaa
     5581 taaataaagg gattcttgca gactaaaacc agataaaagc agttctccca tggtttgtgc
     5641 aaactggttt tgctggcttc ttgttaatcc tttagaatag ttctgactgc caaatatttt
     5701 cctgagcttc ttcataactt tcctcccatg atttttttac tgattcttcc tccataaatt
     5761 gataactcca taaaacagaa ggatggtgat tggcatcttc caaaagttct tgataaatga
     5821 caccagctaa acattcagat agctcttctt ttttctttgt cagttcatgg attctgacca
     5881 atgtaccttc aagattgcgt gcatgtacgg ttgcaaaaac ccggtgccct gttagtgctg
     5941 ctcttaccgc agcatgtgca gttgattcat ctcttatctc gccaatgatt agcaagtctg
     6001 gacgatgccg taatgcgagt ctcaaaagtg tatcataagt ctgtgctatt ttcggattga
     6061 tctgtagctg cagaaaaaac ggttcttcta tctctacagg atcttcgata gtaatcactt
     6121 gcaatttttc ttccaaagcc aaccgataca ttagagaagt cttgcctgat ccgactggtc
     6181 cgctgaaaag gtataatcca cgtctgacgg ttttctgtaa aatagttgca aaatctcgag
     6241 aactaaagca acgatggggt gtttcaaaag taccgtataa tagccgaatc actaaactct
     6301 ctcgttgaag gtaatctcct acagaagaca accgcagacg aacttcctgt ttttctaaag
     6361 aataagtaaa tgcacctaac tgagcttttc ttttttctcc gatatccatc tgtcccaaat
     6421 acttaaatct tgagatcagt tgctgtccat ctgccgaaga gactttcttc cagaatgttc
     6481 gtttttttcc atagcgaaaa tagatgtaaa atacttctga agctggcaat atatatacgt
     6541 cttgggcatg tttggcaaaa ctttcactta tcatttgatc cgataatcgt tttatttcca
     6601 ttattctccc ctccacaaaa aacatacgtc tttttgatct ttttgtttca aataaaatga
     6661 atttacaaaa aaatattggc aaaaaccgaa tttatgttat acttataaaa atttatcttg
     6721 ggaggcactc cattggaaac aacattaagg aaatatatcg aagtagcaag taaaaaaaag
     6781 cctgctgacc tagtgatcaa gcatgctaag atcgtcaacg tctttacgaa agaaatcatg
     6841 gaaaaagatg tagcaatctg cgaaggaatg atcgtaggaa tcggtgaata cgaaggaaaa
     6901 agcgtacata atgctaatgg gcaatatcta gtgccaggat tcatcgatgg ccatgtgcat
     6961 atcgaaagct cacttttatc accaagcgaa ttttcaaaag tatccttgct tcatggagtt
     7021 actactgtag tgacagatcc ccatgaaata ggaaacattg ctgggagtac aggtcttgag
     7081 tttatgatag aagatgcaag acaaacactc atgaatatct tttttatgct accttcttgt
     7141 gtacctgtaa ccccttttga gaccaatggt gcaaatttaa atgcaaaaaa attagcccct
     7201 tttttacaaa aacccgaagt tttaggctta gctgaagtca tgaactatca agcagtagca
     7261 aataatgaaa cagacatcct agaaaagatc caattgatgc accagcataa gaaaaaaatt
     7321 gacgggcatg cagctggtat cggcatggaa gagttaaatg tttatcctgc agcaggtatt
     7381 cggacggatc atgaagctac aactgcaaaa gaagctaaag aacgtttgga tcttggtatg
     7441 tatttaatgg ttcgagaagg gaccgttgca aaagatctgg catcgctact accggcgatc
     7501 acacctgaaa attcaagaag atgcttcttt gtcaccgatg ataaactgat caatgattta
     7561 gtaaaagaag gatcaatcga tcatatcgtc cgtcaagcta ttgcacttgg aatcgatcca
     7621 ttacaagcca ttcagatggc aacattgaat gcagcagaat gttttgattt gaaaacacta
     7681 ggtgcgattg cccctgggta tcaagctgat ttcttcttaa cagacgatct taccaagctg
     7741 ccaattcatg aagttttcta taagggaaca ttagttgttc aatctgggca actccaagac
     7801 catttatttg ctgatcattc aaattcatat acgtgttgtc tgccaaaact aaacgctcaa
     7861 ccattaaatc cacattcgtt agagctgctt ctttcttctt cacaagccca tgtgatcgaa
     7921 attatcccga atagtctagt gactaaagat ttggtagaaa aagtggaccg acaaggcgaa
     7981 cgattcattc cttcaatcga aaaagaccaa ttaaagattg cggtgatcga gcgtcaccat
     8041 caaacgggaa acattggatt aggcatagtg aaaggatttc agctgaaaca aggagcgata
     8101 gcgacaacga ttgcccatga ctcgcataat ctagttgtcg ttgggacaaa cgacgaggat
     8161 atgctgtatg ctgctaatct tttgattcaa aaaggtggcg ggatgaccgt tgtcaacaat
     8221 cagcaggaaa tagcttgtgt ttctcttcct ataggcggaa tcatgacaca ggaacctttt
     8281 tcgatcgtct atgaacagtt gaatgaatta ataactaaag cacatcaact aggagcagct
     8341 aaaacctttg atcctttttt gacactttct ttcttaacat tatctgtcat acccgaattg
     8401 aagatcaccg acaaaggatt attttcattt tctcgcttcc aattgattcc accttgtgga
     8461 aaaaccgatg aaataaatac attttaaatc aaataaatcc cagaaaatac attacatctg
     8521 taatgttcat tttctgggat ttatttatgg atattaatgt ttttatgaaa gcagaaagtt
     8581 agtttcacag acttttcttt ttggtcttat cttgaaattg agcttctact cgataaatac
     8641 gttgaccttt tgaagaaaat ttttcttcat actccgtcat aatattgcct tcaaattgac
     8701 tttgatgtaa atctaaccat acctgtttga ggatcatgcc atattgagaa aaacttgcca
     8761 gagaatactc aaacaatcct tgattatctg ttttgaaatg gatttctcca tttggacgaa
     8821 gaatctgttc atctacagca agaaaagtct tatatgtcaa tcgccgtttt tcatgacgtt
     8881 tttttggcca tggatcggaa aaattcagat agatttgatc tacttcgctg tcagcgaaat
     8941 actctgtcaa cgctgatcca tccacatgta gaagtttcag gttaggaagc ggttgttcga
     9001 tcaacttgtc tagtgcaatc gaaacaacac tgacctgcat ttctactcca atataattga
     9061 tttcaggatg ggcttttgcc attccagtga tgaactggcc tttccccata ccaatctcaa
     9121 tgtggattgg atgatcgttt tcaaacaatt cattccattt tcccttccac aatgttggat
     9181 cactaattac aaaattcggg tgagccgcta acatttccgc tgctcccgga cgatttcgga
     9241 cacgcattat ttatctccat tcctttcctc taattaaaaa ggtctggcca aatctccgca
     9301 gagtttgggc caaacctcag ccactgaaaa ttcgttttaa ttgtaaaatt tcttcgttca
     9361 tccgtcgatg atcttcacgt ttgcaatatc tggtgatttc ttggagcaaa ttcatggccg
     9421 cataccaatg aaatttttca agcatttcgt cagtcgggcg tatgccataa ctgatcagcc
     9481 actgattcca gctagacagt ggcacataat ttcctaaaat cgttgcaata tccaccgcag
     9541 ggtctgcaaa catgattgaa tcccaatcga ctagatataa ataattttta catactaacc
     9601 aattacgatg gtttacatct ccgtgtacta ctgataagtt ttccttatct attgacggga
     9661 tctgctcacg aagaaaacga tggacaattt gcagaaattg atttttctgg agttcttccg
     9721 gtaattcttt ttcatatttt tgcagcatct tctccggcgt catgacacga ccaccgatac
     9781 gggtcagcat ggttttaaga gaatttgaat gatgtaaatg gtacaaaaca tcaatcacgt
     9841 cgtttctttg accaatctca ttaggagtca gcaagcgacc ttccagccac tcttgtgctg
     9901 tcaaagtatc gccattcccc gttcgttttg tccaaacaag ttttggtgta attccttccc
     9961 ttgaaagagc agccaacatc ggagtcgtgt ttcgtttaat aaagactttg tcctcatcac
    10021 gcatgcctat gtatgttttt cctgtgtcgc ctttgatggg acgtaaccgc cactcttggt
    10081 ctaactgaaa ctccatcatg cattctcccg tcctcttact ctttgttttg cagtacttat
    10141 tattctagtc gcctgaacac tacacgtcaa gcacatatac gttctttttc atttaattgc
    10201 cattcaaaaa accagctttt ctcaaaaaaa atagaacgaa cagcattctt actgtcaacg
    10261 ctctattttt cattctcatt tttaccctac acagctttgt tttcagtctg acatcttctt
    10321 caaacgagtt ggtacatata gtttaacaaa gagcatagta acaatcaaat aagccgctag
    10381 cggaacccat cgctgctgcc catctaatac gactgcagca atcaaaccaa aaataaccga
    10441 cgcgataatt aatacccatg tgagtagata ctgaatcgcc tgcttcttct gattcttatg
    10501 gattggataa agctgaacga gaaccatata gcggaactgg ttcgctaaag gtaacagttg
    10561 gaaaccgatc aaatataaaa ataagaaacc gataatcaga ctaaaataaa agtcgactac
    10621 tccggcaatc aataacccac ctataattac taatcggaaa taaagaccac taaaatcaga
    10681 acctcttgcc aatcttcttg caaacaagta aagataagtg ttttttgatt ctcttttaat
    10741 atgagtcaat ataggatcca aatagcgtct tcttttgatc tttgccgtaa tttcaggaac
    10801 atctgtgaat aaattgataa attgatagat ctgatgcaac ctatgttctt ctacatgcac
    10861 cattttctcc caatccaatc ctttttcttg ttgcttccac aaaaaccagt aatatagact
    10921 tgcctgtact aatgcacctg ctattcctgc ccatattagc caataaaatg atagaaacaa
    10981 aaagatcaga gaagaaaaaa accagcctaa tttccaataa cgaataactt gttgatctag
    11041 tcgaaacaat tctgctctct tgatttgcag atgactgaat ttcaaactcc ataatatgat
    11101 cagatagacg aaaaacatcg aaaaggattg ctccgtacta accaccacta atggcatggc
    11161 caatccgcat gccaatatca aaaagatcaa cggaaaaatg caagaatagc gaaaagctcg
    11221 ttccaaatag gtttgcattt ctttttcttt aggaagtaaa aaaacaatat ctgctgcctc
    11281 tgcaaaagta gccatcttac ccacgaataa acagagcatc caaaatacag agattatgag
    11341 ccctccaatt gcaaacggtg gctgcagggt tttcaaccaa ttagaataat ataatcccac
    11401 accgccaatc aagaaaagac aaactaaaac aaaatgatcg ttcaatacat aacgcatata
    11461 tttcatcatt ttcttttgat gtcttgctaa acgtttttga aaaaaactac tcatgtgcct
    11521 gctcctttgt taaagcaata tagatttcgt ccaaagaaga atccggcagc tgaaattctt
    11581 ttctcaacat ctcaagagaa ccgtctgctc gtatctctcc gttatgtaag accacaaaac
    11641 gatcacaata tttttctgca gtagctaaaa tatgcgtaga catcaaaata ccggctcctt
    11701 cttttttcat ttctaccatc aattcaagca atgcattgat agctagtgga tccaagccta
    11761 aaaatggttc gtcgatgata tataaagaag gctcgatcaa aaaggcgcat aagatcatca
    11821 ctttctgttt cattcccttt gaaaaattag ctgggaacca gtcaagacga ttagataacc
    11881 gaaaagtctc caacaacttt tctgctcttt tcattgctat atccataggt atatcgtagg
    11941 ccatcgcagt gacttcgata tgttctctca atgtcaattc ttcatataaa gaaggagtct
    12001 ctggaatata cccaatttgt ttgcgatatt cttccgtatt tttctttaag gatagatgat
    12061 tgatttctat cgttcctttt gaagcttcca gcagaccgat aatgtgcttg atggtcgtac
    12121 ttttccctgc tccgttcagt ccaatcaacc ctactatctc tccaggctgt acatcgaaac
    12181 tgatatcttt taacacaggg agatgtccgt acccccctgt gacatgatcg ataattaaac
    12241 tcattctttt tcctccgcca tttattttta tttattatac cacgaagaaa atgacggtat
    12301 tttgtttttt tccttacaat agctttaact tatggtaaag ttaagctgaa gtatttattc
    12361 tttatagaaa ggatgtttta tatggaaaac tgtatttttt gcaaaatcat caatcaagaa
    12421 atcccaagct ataaaatata tgaagacgac aaggtctatg cttttttaga catctctcaa
    12481 gcaacgaaag gacacacatt agttgtgcct aaacgtcatg tagcagatat ttttgaatat
    12541 gatcccgaac ttgcaggaga ggttttttcg cgtgtgccta agattgctca agcattggaa
    12601 aaagcttttc cagaaatgaa aggtcttaat atcttgaata acaaccgtga actagcctat
    12661 caatctgttt ttcattcaca tatccattta gtccctcgct acagcaaaga ggatgatttt
    12721 tctattcact ttgtcaatca tcaagatagt tatggatcgg aagaactaaa agctattcaa
    12781 gaaacaatcg taaagcaggt gtcctgcgat gattaaaaac tttttcaaag gactgttatt
    12841 tggagctgct gctggcactg tcggaggtct gttattggcg cccaggagcg ggaatgaaac
    12901 aagaaagaaa ctgatcgaag aattggaaga agcaacaact ctgacaaatg atttaaataa
    12961 cagcctgaat cattttaaaa gcgcattgat cgaaacaaaa gaaacagctg aatctgtgat
    13021 tcctgctttc caagaagcaa tcaaaaaaga tatcgaagat tttaaattcc aagccgaacc
    13081 acgtatcaca caaatcaatg aacaagtaga aaaactaaaa gctgatctgc cagagtatcc
    13141 tgaacaaata taataatgat tattttctca acagatttaa ctatataagt gagaaaagtt
    13201 tgcgtatttc ctaggaatgt gatgaaattt tgaattttgt ttgaaactac cacgacaacg
    13261 tttttaaagg aaatgggata tggtatagtt aatatataaa aataataact aattacagga
    13321 gtgcaaattt taatgaaaaa aaaatcaatt attttggcag ctactagtgc gttggctgtt
    13381 ttaactctag cagcttgttc aggcgatact aataaagata tcgcaacgat gaaaggcgga
    13441 acgatcactg tatctgattt ctatgatgaa gcaaaacttg aatcatcgaa ccaatcctta
    13501 gtacaacgga tgatcattta taaagtattc aataacaaat atggcgataa agtaaccgat
    13561 aagcaagtgg atgcagaata cgacaaacaa gcgaaatcat taggtgatac ttttgaatca
    13621 caattagaag ctgctggata tacgaaagat acttataaag aatatattcg taacaattta
    13681 gcttttgaag ctggcttgaa agctcacgta gatattacag atgacgattt gaaaactgct
    13741 tggaaatctt tccatccaga agtagaagca caaatcatca aattatcaag tgaagatgaa
    13801 gcaaaagatg tgaaaaaatc agcggatgat ggagatgatt tctctaaatt agccaaagac
    13861 aaatcaactg atacagagac aaaagaagat ggcggtaaag ttaaattcga ctcaacgaca
    13921 acaactattc ctgcagaagt aaaagaagca gctttcaaat tgaaagacgg tgagatctcc
    13981 gatgttatta ctacaacaaa tcctacttct tatgcgacag aatactacgt tgtcaaaatg
    14041 gtgaaaaacc aaaataaagg caatgacatg gataaataca aagatcaact aaaagatatc
    14101 gctactgaaa ctaaactaag tgacaatgca ttcacaacta aagtaatcgg tgaagaatta
    14161 aaagatgcaa atgtaaaaat caaagatgat gcctttgaaa atgtgttgag tgcattcaca
    14221 acaacttcat caagtacgaa agactcaagt gaaactacag cttcaacaaa gagttctgac
    14281 acaaaatcaa ctgattcaac aaaagaatct tcaactgaag aaacaactga ttcatcaaaa
    14341 taaa
//
LOCUS       DAZAOD010000066        14129 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000066 DAZAOD010000000
VERSION     DAZAOD010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.067"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(41..3694)
                     /gene="rpoC"
                     /locus_tag="ACHDPO_001978"
     CDS             complement(41..3694)
                     /gene="rpoC"
                     /locus_tag="ACHDPO_001978"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFN3369593.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="ACHDPO_001979"
     CDS             complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="ACHDPO_001979"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFN3369594.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8118..9086
                     /locus_tag="ACHDPO_001980"
     CDS             8118..9086
                     /locus_tag="ACHDPO_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369595.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9104..10009
                     /locus_tag="ACHDPO_001981"
     CDS             9104..10009
                     /locus_tag="ACHDPO_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369596.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10006..10812
                     /locus_tag="ACHDPO_001982"
     CDS             10006..10812
                     /locus_tag="ACHDPO_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369597.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10969..11937
                     /locus_tag="ACHDPO_001983"
     CDS             10969..11937
                     /locus_tag="ACHDPO_001983"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFN3369598.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12254..12778)
                     /locus_tag="ACHDPO_001984"
     CDS             complement(12254..12778)
                     /locus_tag="ACHDPO_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFN3369599.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13065..>14129
                     /gene="scm"
                     /locus_tag="ACHDPO_001985"
     CDS             13065..>14129
                     /gene="scm"
                     /locus_tag="ACHDPO_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFN3369600.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         3996 a         3046 c         2791 g         4296 t
ORIGIN      
        1 gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca
       61 ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg
      121 ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga
      181 tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga
      241 tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat
      301 ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc
      361 ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac
      421 ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa
      481 ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta
      541 cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg
      601 gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt
      661 tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta
      721 cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg
      781 tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac
      841 cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag
      901 taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt
      961 cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac
     1021 atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga
     1081 tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta
     1141 cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc
     1201 cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga
     1261 ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca
     1321 aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg
     1381 atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg
     1441 ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag
     1501 aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga
     1561 tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga
     1621 tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga
     1681 tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg
     1741 tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt
     1801 tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata
     1861 ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt
     1921 ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag
     1981 gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc
     2041 attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat
     2101 gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt
     2161 cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc atatcttggg
     2221 aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca
     2281 acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc
     2341 catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt
     2401 gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca
     2461 gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac
     2521 gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac
     2581 gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca
     2641 tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta
     2701 gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg
     2761 ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta
     2821 ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta
     2881 acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac
     2941 ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag
     3001 ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa
     3061 tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt
     3121 tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg
     3181 cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt
     3241 ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag
     3301 caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg
     3361 aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca
     3421 tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc
     3481 ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa
     3541 aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct
     3601 caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta
     3661 tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat
     3721 ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta
     3781 aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt
     3841 cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat
     3901 caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt
     3961 cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga
     4021 atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt
     4081 tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg
     4141 caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag
     4201 ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca
     4261 atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc
     4321 catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac
     4381 cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg
     4441 ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga
     4501 tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag
     4561 gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac
     4621 gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta
     4681 acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt
     4741 gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt
     4801 tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg
     4861 gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac
     4921 ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt
     4981 cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag
     5041 tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc
     5101 cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca
     5161 tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg
     5221 gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat
     5281 ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac
     5341 cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag
     5401 taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac
     5461 ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg
     5521 caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt
     5581 tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg
     5641 ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt
     5701 ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga
     5761 atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag
     5821 gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac
     5881 cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca
     5941 attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt
     6001 ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag
     6061 tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga
     6121 attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat
     6181 catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt
     6241 cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt
     6301 cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga
     6361 ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag
     6421 ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg
     6481 tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta
     6541 attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga
     6601 aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac
     6661 gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt
     6721 ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat
     6781 cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga
     6841 tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag
     6901 ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga
     6961 cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg
     7021 ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc
     7081 cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat
     7141 gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca
     7201 aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc
     7261 cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca
     7321 acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt
     7381 gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt
     7441 tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg
     7501 caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt
     7561 gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat
     7621 agtttttgca acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt
     7681 tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga
     7741 caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga
     7801 ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac
     7861 tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt
     7921 tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct
     7981 aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta
     8041 ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa
     8101 ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac
     8161 tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa
     8221 caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca
     8281 aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa
     8341 atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc
     8401 ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca
     8461 ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca
     8521 atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa
     8581 tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg
     8641 gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg
     8701 tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc
     8761 tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa
     8821 gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc
     8881 aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggtaaacaaa
     8941 cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa
     9001 cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc
     9061 cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc
     9121 tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata
     9181 cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg
     9241 tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct
     9301 aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa
     9361 aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg
     9421 tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga
     9481 gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat
     9541 cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac
     9601 tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat
     9661 cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa
     9721 cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat
     9781 catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt
     9841 aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag
     9901 tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca
     9961 gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta
    10021 acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg
    10081 aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg
    10141 gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa
    10201 attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc
    10261 agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat
    10321 cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa
    10381 gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta
    10441 tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc
    10501 acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct
    10561 acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct
    10621 tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg
    10681 catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc
    10741 caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt
    10801 ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt
    10861 ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt
    10921 gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa
    10981 gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca
    11041 cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca
    11101 ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat
    11161 gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg
    11221 ttgacttctg aatctacgat gaaagatgtc aaactggcag cagctcaagg agattctgtt
    11281 tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt
    11341 ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt
    11401 gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct
    11461 gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa
    11521 gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc
    11581 atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa
    11641 gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc
    11701 agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc
    11761 tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact
    11821 tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa
    11881 cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta
    11941 tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca
    12001 aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta
    12061 aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag
    12121 tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata
    12181 gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt
    12241 tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag
    12301 agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg
    12361 tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa
    12421 tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga
    12481 tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg
    12541 gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa
    12601 tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg
    12661 gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac
    12721 gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt
    12781 attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata cctacttata
    12841 tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga
    12901 ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt
    12961 cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa
    13021 aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa
    13081 gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag
    13141 cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg
    13201 gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg
    13261 cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag
    13321 agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg
    13381 ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta
    13441 acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact
    13501 taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg
    13561 aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat
    13621 atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag
    13681 ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc
    13741 aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat
    13801 tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt
    13861 cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc
    13921 cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg
    13981 gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg
    14041 aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat
    14101 ctaccacaag tgatagctca gattcatca
//
LOCUS       DAZAOD010000067        14071 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000067 DAZAOD010000000
VERSION     DAZAOD010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.068"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..281
                     /locus_tag="ACHDPO_001986"
     CDS             <1..281
                     /locus_tag="ACHDPO_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369601.1"
                     /translation="FFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIP
                     IYVIEDYIWKLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(362..931)
                     /gene="thiT"
                     /locus_tag="ACHDPO_001987"
     CDS             complement(362..931)
                     /gene="thiT"
                     /locus_tag="ACHDPO_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFN3369602.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(997..1099)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(1105..2076)
                     /locus_tag="ACHDPO_001988"
     CDS             complement(1105..2076)
                     /locus_tag="ACHDPO_001988"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFN3369603.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(2170..3543)
                     /gene="glmU"
                     /locus_tag="ACHDPO_001989"
     CDS             complement(2170..3543)
                     /gene="glmU"
                     /locus_tag="ACHDPO_001989"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFN3369604.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(4046..4864)
                     /gene="purR"
                     /locus_tag="ACHDPO_001990"
     CDS             complement(4046..4864)
                     /gene="purR"
                     /locus_tag="ACHDPO_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFN3369605.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(5031..5855)
                     /locus_tag="ACHDPO_001991"
     CDS             complement(5031..5855)
                     /locus_tag="ACHDPO_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFN3369606.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(5828..6508)
                     /locus_tag="ACHDPO_001992"
     CDS             complement(5828..6508)
                     /locus_tag="ACHDPO_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFN3369607.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(6531..7469)
                     /locus_tag="ACHDPO_001993"
     CDS             complement(6531..7469)
                     /locus_tag="ACHDPO_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFN3369608.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(7714..8565)
                     /gene="ispE"
                     /locus_tag="ACHDPO_001994"
     CDS             complement(7714..8565)
                     /gene="ispE"
                     /locus_tag="ACHDPO_001994"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFN3369609.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(8719..11292)
                     /gene="mprF"
                     /locus_tag="ACHDPO_001995"
     CDS             complement(8719..11292)
                     /gene="mprF"
                     /locus_tag="ACHDPO_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFN3369610.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            11433..12239
                     /gene="proC"
                     /locus_tag="ACHDPO_001996"
     CDS             11433..12239
                     /gene="proC"
                     /locus_tag="ACHDPO_001996"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFN3369611.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(12318..13874)
                     /gene="rny"
                     /locus_tag="ACHDPO_001997"
     CDS             complement(12318..13874)
                     /gene="rny"
                     /locus_tag="ACHDPO_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFN3369612.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
BASE COUNT         4076 a         3094 c         2441 g         4460 t
ORIGIN      
        1 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
       61 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
      121 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
      181 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
      241 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
      301 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
      361 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
      421 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
      481 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
      541 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
      601 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
      661 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
      721 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
      781 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
      841 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
      901 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
      961 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     1021 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     1081 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     1141 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     1201 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     1261 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     1321 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     1381 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     1441 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     1501 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     1561 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     1621 catcaaatga tcgactggaa tatcaaagaa accttggatt tggactgcat gaaggtccaa
     1681 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     1741 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     1801 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     1861 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     1921 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     1981 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     2041 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     2101 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     2161 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     2221 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     2281 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     2341 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     2401 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     2461 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     2521 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     2581 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     2641 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     2701 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     2761 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     2821 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     2881 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     2941 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     3001 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     3061 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     3121 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     3181 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     3241 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     3301 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     3361 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     3421 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     3481 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     3541 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     3601 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     3661 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     3721 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     3781 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     3841 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     3901 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     3961 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     4021 aactaagcgg ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     4081 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     4141 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     4201 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     4261 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     4321 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     4381 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     4441 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     4501 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     4561 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     4621 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     4681 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     4741 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     4801 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     4861 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     4921 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     4981 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     5041 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     5101 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     5161 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     5221 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     5281 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     5341 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     5401 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     5461 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     5521 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     5581 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     5641 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     5701 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     5761 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     5821 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     5881 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     5941 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
     6001 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
     6061 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
     6121 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
     6181 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
     6241 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
     6301 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
     6361 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
     6421 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
     6481 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
     6541 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
     6601 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
     6661 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
     6721 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
     6781 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
     6841 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
     6901 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
     6961 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
     7021 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
     7081 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
     7141 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
     7201 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
     7261 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
     7321 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
     7381 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
     7441 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
     7501 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
     7561 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
     7621 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
     7681 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
     7741 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
     7801 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
     7861 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
     7921 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
     7981 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
     8041 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
     8101 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
     8161 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
     8221 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
     8281 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
     8341 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
     8401 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
     8461 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
     8521 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
     8581 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
     8641 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
     8701 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
     8761 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
     8821 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
     8881 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
     8941 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
     9001 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
     9061 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
     9121 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
     9181 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
     9241 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
     9301 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
     9361 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
     9421 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
     9481 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
     9541 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
     9601 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
     9661 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
     9721 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
     9781 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
     9841 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
     9901 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
     9961 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    10021 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    10081 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    10141 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    10201 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    10261 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    10321 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    10381 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    10441 aactactgct acatcttgcc gaacagacaa ttgactcatt cctaagatca tcaaaacgtc
    10501 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    10561 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    10621 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    10681 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    10741 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    10801 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    10861 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    10921 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    10981 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    11041 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    11101 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    11161 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    11221 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    11281 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    11341 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    11401 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    11461 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    11521 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    11581 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    11641 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    11701 tcatttctat tgcttcagga aaatcattaa tagatttaga aacagcgctt gaagatcctc
    11761 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    11821 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    11881 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    11941 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    12001 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    12061 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    12121 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    12181 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    12241 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    12301 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    12361 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    12421 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    12481 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    12541 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    12601 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    12661 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    12721 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    12781 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    12841 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    12901 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    12961 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    13021 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    13081 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    13141 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    13201 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    13261 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    13321 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    13381 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    13441 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    13501 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    13561 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    13621 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    13681 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    13741 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    13801 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    13861 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    13921 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    13981 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    14041 aaacggcttt ctacttattc attaaacgat g
//
LOCUS       DAZAOD010000068        13665 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000068 DAZAOD010000000
VERSION     DAZAOD010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.070"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            65..307
                     /gene="yaaA"
                     /locus_tag="ACHDPO_001998"
     CDS             65..307
                     /gene="yaaA"
                     /locus_tag="ACHDPO_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFN3369613.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            294..1418
                     /gene="recF"
                     /locus_tag="ACHDPO_001999"
     CDS             294..1418
                     /gene="recF"
                     /locus_tag="ACHDPO_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFN3369614.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1415..3361
                     /gene="gyrB"
                     /locus_tag="ACHDPO_002000"
     CDS             1415..3361
                     /gene="gyrB"
                     /locus_tag="ACHDPO_002000"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFN3369615.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3381..5852
                     /gene="gyrA"
                     /locus_tag="ACHDPO_002001"
     CDS             3381..5852
                     /gene="gyrA"
                     /locus_tag="ACHDPO_002001"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFN3369616.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6088..6387
                     /gene="rpsF"
                     /locus_tag="ACHDPO_002002"
     CDS             6088..6387
                     /gene="rpsF"
                     /locus_tag="ACHDPO_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFN3369617.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6437..6949
                     /gene="ssb"
                     /locus_tag="ACHDPO_002003"
     CDS             6437..6949
                     /gene="ssb"
                     /locus_tag="ACHDPO_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFN3369618.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            6975..7211
                     /gene="rpsR"
                     /locus_tag="ACHDPO_002004"
     CDS             6975..7211
                     /gene="rpsR"
                     /locus_tag="ACHDPO_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFN3369619.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7354..9327
                     /locus_tag="ACHDPO_002005"
     CDS             7354..9327
                     /locus_tag="ACHDPO_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFN3369620.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9333..9785
                     /gene="rplI"
                     /locus_tag="ACHDPO_002006"
     CDS             9333..9785
                     /gene="rplI"
                     /locus_tag="ACHDPO_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFN3369621.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10059..11426
                     /gene="dnaB"
                     /locus_tag="ACHDPO_002007"
     CDS             10059..11426
                     /gene="dnaB"
                     /locus_tag="ACHDPO_002007"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFN3369622.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12206..13498
                     /locus_tag="ACHDPO_002008"
     CDS             12206..13498
                     /locus_tag="ACHDPO_002008"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFN3369623.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4557 a         2469 c         3010 g         3629 t
ORIGIN      
        1 gttttattgc gaaaaaaaag gtataataga gtatactttt aataatgaaa atgagggatg
       61 ggcattgaaa caacaagtca ttctaaatac ggaattcatg acgttgggcc aaatgttgaa
      121 agaagtcaca gttatcggta gtggcggaca agcaaaatgg tatttggcag aaaacactgt
      181 gttagtcgat ggcgaaccag aaaatcgtcg tggacgcaaa ctttatcccg gcatgatggt
      241 tgaagttcca gaagtaggaa ctttttttat ggtaaaaaaa ggaaacgacg ataatgaggc
      301 tgaataagct gtatttaaaa aattatcgaa attacgaaga gctgaacatc gaattttcca
      361 agaacctcgt catcttttta ggagaaaatg cgcaaggaaa aacgaatctt ttggaaagta
      421 tctacgtatt agctatgacg cgaagtcatc ggacaagtag tgagcaggaa ttgattggct
      481 ggactgacga tcaggcgatg attcaaggag agatcacaaa aggttcatcc actcttccat
      541 tagaaatctt attatctaaa aaaggccgaa aaaccaagat caaccatatc gaacagaaaa
      601 agttaagtac ttacgtggga caaatgaatg tcattttatt tgcaccagaa gatctttctt
      661 tagtaaaagg cagcccgcag atcaggcgga agtttttaga tatggaatta ggccagatca
      721 atccaatcta tctttatgat cttgtccaat accaagcaat tttgaaacaa agaaaccagt
      781 acttgaagca attgaatgaa aaaaaacaaa ctgatttgct ttatttggat attttgtccg
      841 aacaactagc agcgtttggc agcaaagtat tgaaagcaag agcacagttc gtcaagcgat
      901 tggagttttg ggctaattct ttgcatcagc aaatcaccca tcaaaaagag cagctggaaa
      961 tcgagtatct caccgcagtc gattctttag aaacacatac gcaagagcaa atccaagaac
     1021 aatttctcgc acttttgaac caaaataaaa agaaagacct ttttcgggga acaacgacag
     1081 ttggtcctca tcgtgacgat ctttcctttt ttattaatca gaaaaatgtg cagacttatg
     1141 gatcgcaagg acagcaaaga acaactgcac taagtgtcaa attagcagaa atcgatttga
     1201 ttaaagaaga gacaggggaa tatccaatcc ttttgttaga tgatgtgatg agcgagctgg
     1261 atgataatcg tcaactccat ctgctagaaa caatcgaagg aaaagttcaa acgttcttaa
     1321 caacaacgac acttgaccat gtaaaaaata aaatgactgt tgaacctgag attttttatg
     1381 ttcaacaagg gaaactaaaa ggagaagaaa ctgaatgaca gaagaaagaa gtttagtaga
     1441 acgcgctaaa gagtatgatg ccagtcagat tcaagtactt gaaggacttg aagccgttcg
     1501 taaacgacct ggcatgtata tcggttcgac tagttctgag ggtctgcatc accttgtttg
     1561 ggaaattgtc gataattcga tcgatgaagt attagcaggt tttgcaacga aaatccatgt
     1621 gattattgaa aaagacaaca gtatcaccgt tattgacgac ggtcggggga tacctgtaga
     1681 tatccaggca aaaactggac gtcctgcagt tgaaacggtc tttactgttt tacatgctgg
     1741 aggaaaattc ggcggtggtg ggtacaaagt ttctggtgga cttcacggag taggatcttc
     1801 tgttgtaaac gcgctttcta cacagcttga tgtcaaagta tacaaagaag gaaatgtgta
     1861 ctatcaagaa tatcgtcgtg gagctgtagt ggacgactta aagattatcg aacaaacgga
     1921 tcgccatgga acaacggttc actttacgcc agaccctgaa atttttacag agacaactga
     1981 gtttgatttt tcaaaattgg ctacccggat ccgtgaactt gctttcttga accgcgggat
     2041 gcgtatatcg attgaagaca aacgagaaga agaaccagtc atcaatgaat accattatga
     2101 cggcgggatc aaaagttatg tcgaatactt gaatgcaaac aaaaccgtga tttttccaga
     2161 acctgtatat ttggaaggtg aacagcaaga tatcgcagtt gaagtctcta tgcaatatac
     2221 agacggctac cattccaata tcatgagttt tgccaacaat atccatacgt atgaaggtgg
     2281 aacacatgaa tcaggattca agactgcttt aactcgtgtg ataaatgatt atgcccgaaa
     2341 acaaaagctg atgaaagaaa atgacgacaa cttgaccggt gaagacgtgc gagaaggatt
     2401 gacagctgtt atttctatca agcatcctga ccctcaattc gaaggacaaa caaaaacaaa
     2461 attgggcaat tccgaagtac ggacagtcac tgatcggtta tttagcgaac atttcatgaa
     2521 attcttgctg gaaaacccaa gtgtgggccg gcaaattgtt gaaaaaggat tactagcttc
     2581 cagagctcgt ctagcagcga aacgtgcgcg tgaagtaacg agacgtaaag gtgctttaga
     2641 gattagtaat ctgccaggaa aattagcgga ctgctctagc aacgatcctg aaaaatgcga
     2701 attgttcatc gtcgaaggag attcggccgg cggatcagct aagcaaggtc gtaatcgaga
     2761 gtttcaagcc atcttgccta ttcgtgggaa aatcttgaat gttgaaaaag caagcatgga
     2821 caagatcttg gcaaatgaag agatccggtc tttatttact gctatgggta cagggtttgg
     2881 agaagatttt gatgtatcga aagctcgcta ccacaaatta gttatcatga ctgatgccga
     2941 tgtcgacggc gcgcatatcc gtacattgct gctgactctt ttttatcgtt acatgcgtcc
     3001 tattgttgaa gctggatacg tctatattgc tcagccacct ttatacgggg taaaacaagg
     3061 gaagaatatt acgtatgtac aaccaggaaa aaatgcagaa gaagagttga aacaagtcgt
     3121 tgcttcactt cctgcctcac caaaaccaag cgttcagcgt tataaaggac ttggagaaat
     3181 ggatgatcat caactatggg aaacaactat ggacccaagc aatcggatga tggcccgcgt
     3241 cagtgtggac gatgctattg cagcagatca gatatttgaa atgttgatgg gggatcgagt
     3301 agaaccccgt cgtgcattca tcgaggaaaa tgcacactat gtgaagaact tagatattta
     3361 atcatgaagg aggaaaaaga atgagtgaag aaatcagaga aaacatccat gatgtcaatc
     3421 taaccagcga aatgaaagac tccttcatcg attatgcgat gagtgttatt gtcgcacgtg
     3481 cacttcctga tgtcagagat ggtctgaaac ccgttcatcg ccgtatttta tacggcatga
     3541 acgaattagg tgtaacaccg gataaagccc ataaaaaatc tgccagaatc gtcggagatg
     3601 tcatgggtaa ataccatcct catggagaca ttgcgatcta tgagtcaatg gtacggatgg
     3661 cacagccatt cagctaccgt tatatgctag tggatggtca tggaaacttt ggttctgttg
     3721 acggtgacgg tgccgccgct atgcgttata ccgaagcacg gatgagcaaa atcgctacag
     3781 aaatgctgcg tgatatcaat aagaacactg ttgatttcca aagcaactat gatgatacag
     3841 aaaaagaacc agttgtacta cctgctcgct tcccgaatct tttagtgaac ggaacaacgg
     3901 ggatcgccgt aggtatggcc acgaatatcc cacctcataa cttgtctgag gtagtagcgg
     3961 ctatcgattt gctgatggat aatcctgatg tgacgaccaa tgaattgatg gaagtattac
     4021 ctggaccaga ttttccaaca ggtggtttgg ttatggggaa atcaggaatc cgaagagcgt
     4081 atgaaacagg taagggttct attaccgtac gtgcaaaagt tgagattact gagatgccaa
     4141 atggtaaaga acggatcatc gtgacagaat tgccttatat ggtcaataaa gcaaaattga
     4201 tcgaacggat ttctgaactg cacagagaca agcgtatcga agggatcaca gatttgcggg
     4261 acgaatcttc ccgtgaaggt atgcggatcg tcattgacat ccgtcgtgac gccagcgcat
     4321 ccgttatctt gaataactta tataaattga catccttgca aaattcattt ggattcaata
     4381 tgttggcgat cgaaaaaggt gtgccgaaag ttttgagctt gaaacaaatc cttgaaaact
     4441 atatcgaaca tcaacgcgaa gtcatcacac gacggacggt ctttgaaaaa gaaaaagcag
     4501 aagcaagagc acacatctta gaaggtttgc gtattgcttt ggatcatatc gatgaaatca
     4561 ttgcgattat ccgcgggtct aaatcagatg acgaggcaaa agcaacaatg atcgaacggt
     4621 tcgatttatc cgatcgccag tctcaagcta ttttagatat gcgtttacgc cgattgaccg
     4681 gtttggaacg ggaaaaaatc gaaaatgaat accaagaact cttaaaactg attgaagatt
     4741 taactgacat tctggcaaga ccagaacgtg ttacagaaat catcaagaat gaattagcag
     4801 acttgaatca acgatttggt gataaacgac gcacagaatt actagtcggt gaggtcttaa
     4861 gtctggaaga tgaagattta atcgaagaag aagaaatcgt tattacattg acaaacaatg
     4921 gttacatcaa acgtttggca aataatgaat tcagagctca acgaaggggt ggacgtggtg
     4981 tccaaggaat gggtatccac aatgacgact tcgtcaaaaa tctggtttct tgttctaccc
     5041 atgatacatt gttattcttt acgaataacg gaaaagtgta tcgggcaaaa ggatacgaaa
     5101 ttccagaata cgggcgtaca gccaaaggaa tcccaatcat caatttacta ggtatcgatt
     5161 cgagtgaaag catccaggca atcattgcgg tgacgggaga agcagaagaa ggccactatc
     5221 tcttctttac gacgcgtcaa ggtacagtaa aacgtacttc tgtcactgct tttgctaaca
     5281 tccgaagtaa tggtctgatc gcaattggtt tgaaagaaga cgatgagctc gtcaatgtgc
     5341 tactgacaga tggtcaatct aatatcatta ttggaacaca taacggctac tctgtcactt
     5401 tcaaagaaga agcagtccgc gatatgggac gtacagcttc cggggtcaga gggatacgcc
     5461 tgcgtgagga agattatgtc gttggggcag ccttaatgaa ggaaaatcaa gaagtattag
     5521 tgatcacaga aaaaggttac ggaaaacgga caaaagtatc ggaatatcca gtgaaaggcc
     5581 gcggaggtaa agggatcaaa acggcgaaca tcactgaaaa aaatggtcca ctagctggat
     5641 tgaccactgt ttctggagat gaagacatca tgctgattac agataaaggt gtcattatcc
     5701 gtttcaacgt atcgactgtt tctcaaactg gacgttcaac attaggcgta cgtttgatga
     5761 agatggaagc tgatacgaaa gttgtcacga tggcagcagt cgaaccagaa gctgcagaac
     5821 aaacagttga agaacaagga tcagaagaat aaccatcaag actaagtgtg taagctagca
     5881 agaataaccg attaaaaaat ctggttattc ctgctggctt ttttgattag ttgaatttct
     5941 cttaaaatat tcgaaactgt tcattctgta ttgcttttga ccaaaataga gtgtataatt
     6001 agagcttgtg agtagtctaa ttaattagat aactctcctt gctcttagga acctaagagc
     6061 cgaaagtcca cagggaggtg aatatcaatg gaaaacacga aatatgaaat catgtacatt
     6121 attcgtccaa acattgatga agaagcaaaa actgctttaa tcgaacgttt cgatgcaatc
     6181 ttgaaagata acggagcaga agttatcgaa tcaaaagatt gggaaaaacg ccgtttcgct
     6241 tatgaaatga acggttaccg tgaaggtatc tatcacatcg ttaaagtatc ttctccatca
     6301 tcagcaaatg ctgtcaatga atttgaccgt cttgctaaaa tcaacgacga tatcattcgt
     6361 cacatgattg ttaaagaaga agcttaattg ttgtttcatg tgaaacaata gaaaacgatg
     6421 agaggagatg actattttga ttaataatgt tgtattagtt ggacgtctga cgaaagatcc
     6481 agatttgcgt tacacagcaa gtggtacggc agtcgcaaca tttactttgg ctgtgaatcg
     6541 taattttaca aaccaaagcg gcaatcgcga ggctgatttt atcaactgtg tgatttggcg
     6601 caaatcagca gaaactttag caaactatgc tcgtaaagga acacttttag gtgttactgg
     6661 acgtatccaa actcgttctt atgataatca gcaaggacaa cgtgtatacg tgacagaagt
     6721 agtagctgac aacttccaat tgctggaaag tcgttctgca tctgaaaatc gccaacaaag
     6781 cggcggattc caaagttctg gtcaatcagc tggcggattt ggcggaaaca ataactctaa
     6841 tcaaacatct caatcatcca acggtatgcc tgatttcgac cgtgatactt ctgacccatt
     6901 cggctcaagt tcaacgatcg acatttcaga cgatgattta ccattctaaa cgaatttgat
     6961 aggagggaaa tagaatggca caacaaagaa gaggcggacg taaacgtcgt aaagtagact
     7021 acattgctgc taaccatatt gaatatatcg attataaaga tatcgaatta ctaaaaagat
     7081 ttatttcaga acgcggtaaa atcttgccac gtcgtgtaac tggtacaggc gctaaaaacc
     7141 aacgtaaaat tactgttgca atcaaacgcg ctcgtatcat gggcttgcta cctttcgtta
     7201 gcgaagacta ataaatccta ggaattgaat gactgatcct tttgatcagc tattcaattc
     7261 ctttttttct gtaaaaataa cctctattcg tttagtcgct cgaatgacga aagttatggt
     7321 aaaatcaaat tagtcatata tgggaggaaa attatggaaa ataaaaacaa tcatttatcc
     7381 ccgaaacctc tcttccttat cctgtttata ttaatcgaag tattggtagt cttaatttta
     7441 ccatttcgtt ttgttagcgc ttcggtcatt ctattgatga atttatgggg tgttcgctat
     7501 tggttgaaaa tgaaacgttg gcttatttta aataaacgtg aaaaaatcca gcaggcttcg
     7561 actgtagctg aaaccaatct agcttatgtc tcagaagtca tgcctgtagg agtgattgct
     7621 tatcagccat caagccaaaa aatcgaatgg ctcaatccat tagcattgaa aatcaaagat
     7681 caaagtggat taacagagga agaattgcta gatacttttt ttactgcaaa agaaaaaaag
     7741 aaaaaccaag tctatctagc agataaaaca tttcagtttg atatggatac agtaaagggt
     7801 gttgtttatt ttaatgatat tacccaaaac cagttgttaa aactccatca gacgaacagt
     7861 cagccggtga ttggtatttt atctattgat aactatgcag atgccattga taaattagat
     7921 gacaaagaga tttcttattt gaactctttc gtcactacac tagtttctga ctggatgaat
     7981 gaataccatg tctttttcaa aagaatcaac gcagaacggt ttttcttcgt agcacagatg
     8041 atcgatctga aaaagatgat ggataaaaaa tttgatttgc tggatcgctt tcgagcagaa
     8101 gctgaaaaac agagctcgcc tatcaccctt agtatgggga ttgcttatgg ctcaagaacc
     8161 ctcgatgaaa tcggtggaga agctcagaat aatttagatg ttgctttagt ccgtggaggc
     8221 gaccaagttg tcgtgaaaga ggtaaaagaa ggagcaaaac ctgtttatta tggggggaaa
     8281 tctgctaaga atgtcaaacg cacgcgtgtt cgttctcgag cgatgagtac cgctttgcgt
     8341 cggatttttg atgaaacagg cgatgtgttt atcatggggc acaagtttcc ggatatggat
     8401 gctttaggct ctgcttttgg tgtcagttgt ctggcacgct tcaaccagaa aaaagcttac
     8461 atcgttatca atgagaacga gatcattcca gatgtagaac ggtgtcttga agaaatccat
     8521 aagcatcctg aattagaaat gcaactaatc tctccagaac gtgccataga gctgaaaaaa
     8581 gaagaggacc tcctcgtgat ggtggattac cataaacctt ctctatcgat ctctcagggc
     8641 ctatatgagc aatttgataa gattgtgatc attgatcacc atcgtcgtgg ggaagagttt
     8701 ccaagtaaac ctctgctgac ttatattgaa tcttcagctt cttcagcttc agagctagtt
     8761 tctgagctga tccaatacca aagcagcaaa acaaatcgct tagatcgttt tgaggccaca
     8821 ttattgcttg cagggatggt tgtagataca aatagtttca atgtccgtac aactgcacga
     8881 acttttgacg ttgccagcta tttaaggtct tgtggagcag acgcatcctt agtacaatat
     8941 ttattgagct cggatttagc gacatacttg gagatcagca atttgattgc tggaagcgac
     9001 tatgtgactt ctgatattgt tgtggcggca gggacagacg aaaaagagta taatagtgtt
     9061 atagcagcaa aaacagcaga tacattgctt tcgatgatca atatcaatgc agctttcgtc
     9121 attacaaagc ggacagacgg cttgattggg atcagtgcca gaagtaccgg cacgatcaac
     9181 gtccaaatca tcatggaatc cttaggtggc ggaggacact tcacaaacgc agctactcaa
     9241 ctggaaaata cgacagttga ggaaacaaaa cagaagctat ttgctgcaat caaagaaaat
     9301 atgaatcaaa tatatgataa ggagtaatcc aaatgaaagt aattttttta caagatgtaa
     9361 aaggaaaagg taaaaaaggg gacatcaaag aagttccagc aggttatgca caaaattatc
     9421 taatcaaaaa taacttggca aaagaagcaa cgaaaagcag tatcagtcag ttagcaggac
     9481 aaaagaaagc acaagaaaaa cacgaagctg aaatcttgga agaagctaaa aagttaaaag
     9541 aattcttgga aaaagaagat actgtagtcg aattgaaggc gaaagcaggg gaagacagcc
     9601 gtttgtttgg ttcgatccct tcaaaacaaa ttgctgaagg gttaaacaaa caatacaaaa
     9661 tcaaattaga taaacgaaaa atcgaattag aaaatccgat ccgttcacta ggctacacaa
     9721 acgtacctgt taagcttcat catgaggtga cggctacgat caaagttcat gtcgtacaag
     9781 aataacaaat cttgatagcg atgttcagct ggtaagtata accagaagga aaaaagacaa
     9841 accgaaattt atctgagaaa acagctgcag caatgaaagc aaaagctgca aatcgatttc
     9901 agattgattt cggtttcttt tttgggaaca gcaaaatagc ataaagaaaa cgagtataat
     9961 aaaagagaac tattttttta ttacactttc ggtacgaatg atgacttttc tctcattttc
    10021 ttgtaaaatg aagcaattga agacaaggag cgatacgtat gaatgaagtg tggcaggatc
    10081 gaatcccacc gcaaaatatt gaagctgaac aagcggtttt aggctctgtt tttcttgacg
    10141 cagaaacgat cattgatgcc atggagtaca tagagccaaa agacttttat cgtcgtggcc
    10201 atcaaattat ttttgagaca atgatcgagt taaatgatcg taatgaagcg attgacgtgg
    10261 ttactgtcaa agaccggctg gaacaagcca atttgttaga agatgccggt ggtttaagtt
    10321 atctctcaga cttggcatta gcagttccga cagcagcaaa tatcgtctac tatgcgaaaa
    10381 tcgttgaaga aaaatcattg ctgcgtacat tgatccagac agcaacagga atcgttacga
    10441 aaggattcga gcaaggagaa gaagttcaaa caattttaga tgatgccgaa cgcagtatct
    10501 tggaggtttc ggaaaaaaga aatcgaagcg gctttttatc tattgctgaa gtactgaact
    10561 ccacgattga aaatatcgat cgactagctc aaaacaatga agaaatcaca ggtctaccaa
    10621 ctggctatca aggtctggat aaaatgacag caggtttcca gcccgaagaa ctaatcattc
    10681 ttgctgcacg tccagcggta ggtaaaacag cgtttgcatt gaatattgct caaaatgtag
    10741 gaacaaaaac agatcgttct gttgcgatat ttagtttgga aatgggggca gaatctcttg
    10801 taaatcggat gctttgtgca gaaggttcga ttgaggccag ccatttacgt acaggtcagc
    10861 tttcggaaga agaatggtcg aatctgatcg ttgcgatggg gagtctttct cgagcaaata
    10921 tttttatcga tgatacacca gggatcaaaa tctctgaaat ccgtgcgaaa tgtcggaaac
    10981 tagcgcaaga aaaaggcaat ctaggcttga tattgatcga ttatttgcag ttgattgaag
    11041 gtaacggtaa agagaaccgt caacaagaag tatcagatat ctctcgccaa ctgaaaaaac
    11101 tggcgaaaga gctgaaagta cctgtcattg ctctttcaca gttatctcgt ggagtagaac
    11161 agcgacaaga caaacgacca gtgctaagtg atattcgtga atccggatca attgaacaag
    11221 atgcggacat cgtagccttc ttgtatcgag atgattatta tgaaagagaa ggcggagatg
    11281 acgatgatgg aaacgagcca aaaaatgaca acgtcatcga agtcatcatc gagaagaacc
    11341 gaagcggtgc acgaggaaca gttgaactac tgtttatcaa agaatacaat aagttttcgt
    11401 cgctttcgcc aagagaagaa ttttaaagaa gaggttgtga gccttgagca atcccgagag
    11461 ctctcgtaag aagatgcaag gagtaaccgc aggaacgact agagtactta atttaaacag
    11521 atctccaaag ggattgtgac aaaagtcttg tcacagtccc tttttccgaa taaacggtgt
    11581 tcaatcagct gacccttggt attagctcag caaacgtcaa aatatgagga actattttga
    11641 cgtttgtttc tctaatactc aggtcaaaac gctgatctta cgacctcttt tccttaaacg
    11701 gtgttctcct gccaactcct cggtcacaag tcacaatatc atcaaacatg agaagcagtt
    11761 ttttgaaatt gctccttgtg actcagagtt aaacggcagg ctcacaacct ctttcttaaa
    11821 cggtgttcaa aagcttgcat ctgcggtaat acgcccaatc aaacgaaaaa tatgagaagc
    11881 tatttttgtt tggctgttct tattacttga tgcaggacag ctttttcaca acctctgatt
    11941 cacggtgttc caaaagtagc ttcttcgaaa aataagtcga aatttcacaa aaatttgaga
    12001 agcaattttc gtacattcct tcttatttct tgaagctgac cacttctgtt acaacctctt
    12061 ttttaataac cattctaaaa agataaagtt cgttttttaa gcgtttttat aaaataaaaa
    12121 taaaaatcat tcgattttat ttgaaatatg tatctattat tgatacaatg gttcaggatt
    12181 aaataatata gaacgaggtg ttcacatgtc atctgtagta gtagtaggta cgcaatgggg
    12241 cgatgaaggg aaaggaaaaa tcacagactt tctcagtgaa aatgctgaag tgattgcacg
    12301 gtaccaaggt ggcgacaatg cagggcacac aattaagttt aacggtgtga cttataaact
    12361 gcatttgatt ccttctggga ttttttataa agacaagatc agtgtgatcg gaaacggcgt
    12421 tgtagtcaat cctaaatcat tggttaaaga attagcttat ttacatgaaa aaggtgtaga
    12481 aacaagtaat ttgcgtattt ctgaccgcgc gcacgtaatc ttgccttatc atatcaaatt
    12541 ggaccaatta caagaagatg ctaagggcga aaataagatt ggtacaacga ttaaaggaat
    12601 cggacctgcc tatatggata aagcagctcg tgtaggtatc cgtattgcag acttattaga
    12661 taaagaaatt tttgaagaac gtcttcgttt gaatctagat gacaaaaacc gtcaatttgt
    12721 aaaaatgttt gattcagaac cacttgattt tgacgatatt tttgaagaat attatgaata
    12781 cggacaacaa atcaaacaat acgtcacaga tacttccgtt atcttgaatg atgctttgga
    12841 tgcaggcaaa cgcgtgttgt ttgaaggcgc acaaggtgta atgctggata tcgaccaggg
    12901 aacttatcct tttgttactt cttctaaccc agtagccggt ggggtaacaa tcggaagcgg
    12961 tgtagggcct tcaaaaatca ataaagttgt cggcgtctgc aaagcctata cgtcacgtgt
    13021 cggtgatgga ccatttccaa ctgaattatt tgatgaaaca ggagaacaaa tccgcgaagt
    13081 aggacgagaa tacggtacga caactggtcg tccgcgtcgt gtaggctggt ttgattctgt
    13141 agttatgcgc cattctaaac gagtttcagg tattaccaac ctatctttaa actcgatcga
    13201 tgtattaagt ggattggaaa cagtaaaaat ttgtacggct tatgaattag atggcgaact
    13261 aatctaccac tatccagcaa gcttgaaaga gttgaaccgc tgcaaaccaa tctatgaaga
    13321 attgccaggc tggtcagaag acattacagg atgcaaaaca cttgcagaac tgccagaaaa
    13381 cgcacgtaac tatgtacgtc gtatctcaga gcttgttggt gtacgtatct caacattttc
    13441 tgtcggacct gatagaacac aaacaaacat cttagaaagc gtctgggcgc aaatctaagg
    13501 ataaaaacga cgactgaatc aggacgttct taccagagcg agtcgaagtg tttatctata
    13561 cgataataat aacttgaaga ggtagtgaaa gagacgttta gccttattgc cgataggctg
    13621 tctcttgaac actgtttatt cagaataagg gactgtgaca aaaac
//
LOCUS       DAZAOD010000069        13551 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000069 DAZAOD010000000
VERSION     DAZAOD010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.071"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            14..1651
                     /locus_tag="ACHDPO_002009"
     CDS             14..1651
                     /locus_tag="ACHDPO_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369624.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(1796..2536)
                     /gene="truA"
                     /locus_tag="ACHDPO_002010"
     CDS             complement(1796..2536)
                     /gene="truA"
                     /locus_tag="ACHDPO_002010"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFN3369625.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2727..3362)
                     /locus_tag="ACHDPO_002011"
     CDS             complement(2727..3362)
                     /locus_tag="ACHDPO_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFN3369626.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3509..4729)
                     /gene="sstT"
                     /locus_tag="ACHDPO_002012"
     CDS             complement(3509..4729)
                     /gene="sstT"
                     /locus_tag="ACHDPO_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFN3369627.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            4948..5946
                     /locus_tag="ACHDPO_002013"
     CDS             4948..5946
                     /locus_tag="ACHDPO_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369628.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            6142..7977
                     /locus_tag="ACHDPO_002014"
     CDS             6142..7977
                     /locus_tag="ACHDPO_002014"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFN3369629.1"
                     /translation="MQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLL
                     LLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVL
                     LIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSP
                     SFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYN
                     TKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLM
                     LSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHP
                     FTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNT
                     ETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKF
                     IQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNK
                     EVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTE
                     DSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8037..8753)
                     /locus_tag="ACHDPO_002015"
     CDS             complement(8037..8753)
                     /locus_tag="ACHDPO_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFN3369630.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(8980..9522)
                     /locus_tag="ACHDPO_002016"
     CDS             complement(8980..9522)
                     /locus_tag="ACHDPO_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFN3369631.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(9527..9754)
                     /locus_tag="ACHDPO_002017"
     CDS             complement(9527..9754)
                     /locus_tag="ACHDPO_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFN3369632.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(9833..11713)
                     /locus_tag="ACHDPO_002018"
     CDS             complement(9833..11713)
                     /locus_tag="ACHDPO_002018"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFN3369633.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(11902..12516)
                     /locus_tag="ACHDPO_002019"
     CDS             complement(11902..12516)
                     /locus_tag="ACHDPO_002019"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3369634.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            12658..13218
                     /locus_tag="ACHDPO_002020"
     CDS             12658..13218
                     /locus_tag="ACHDPO_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3369635.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
BASE COUNT         4246 a         2634 c         2139 g         4532 t
ORIGIN      
        1 ataggagaaa aaaatgaaaa aaaacaaaaa ccaaataata gatatcattt ttatgttatt
       61 tctaagtttt gcttacgtca tccctctatt catgtctaag ggaatctatc atagtgtcaa
      121 tcaggatact tactttcatt tatctcgaat cataggacta gataatgtat ggagttctcc
      181 agtaaacttc aataacttcg atcatcatgg aacaatgatg aatatttttt atccatggct
      241 tactctttat ccagcttttt tattttataa aatgatggga aatcttgttt taagttataa
      301 tatctactat ttttttatca cttttttaac aatggtcgtt tcttattttt ctatgaaaca
      361 aataaaaaac aatcgttata tttcgctgtt attttcgatt atttatacat tttccgccta
      421 tcgtgccatt gacatattcc atcgtgcttc attgggagaa gctgtcgctt taacattttt
      481 gcctttgata ctaatggggt gttacgaaat ttatattaga gattaccaaa aatggtactg
      541 gttgtctatt ggcatgacgc tagtagtgta tactcattta ctttctgtcg ctatggtttc
      601 tgtatttatt ggaggaacgt tgtttctttc tttttatttt tgggaccaaa aaatcgctag
      661 actcttaagt cttttaaaag ctaccgtcct cacctttttt ttaagtgcgg gattcttaat
      721 tccttttatt caacaatcta gagcacaaga attgaaagtc ccactgggaa aagaattaag
      781 tggtatggct cctagtgata tgctgacaca tattttaaat aataactata acaactatac
      841 tattggatta ttcttatttc tcggattgat tggtgctttt atttttataa aaaaattaac
      901 tgctgatgat ttatttattt tctttcttgg tgtatttgtt cttttttgtt caaccaattt
      961 atttccttgg caacttttta accatacacc agttaagagt ctacaatttg tctggcggtt
     1021 aaatggtttt tcttctttat ttatagccta tacgatgagt atagtgatct attatatttt
     1081 ttctactaaa aataattcat ggaaaataat ggtctttacg tttcttgcac taatattgca
     1141 tctctcagga gtaagcaatt ctatccatgc taacaaagat tcattaacac ttatagcacc
     1201 tgaagacgct gttgctatag ctgaaaatta caatcatact gattatgcaa acaaagagtc
     1261 aatctatcat cctgatatga ttaataatga tcaatattta ctaggtaacc aggaaataaa
     1321 tccaacaact cattttatga gtaacaaact tacaattgaa ttagataatt cgaataataa
     1381 aaatactgtc ttgacgacac ctatttatcg ttataaaggg caagtggctt ctattaatgg
     1441 caaactagta caaacaaaat tatctaagtt tggcacaact gaattaacta ttcctccagg
     1501 tataaataaa gtcgttatta cttatcagta cacaaaacta gcaattgctt caagatattt
     1561 atctatcgtt actttgattt tatttttact ttatcgattt actttttcta aacaaaaaca
     1621 accgagaaga gaagtacaac attctcacta gatttttatt taagaaagac tttttagctg
     1681 tacacataaa caggctaaaa agtctttttt tatatttctt taatttgctt catacattat
     1741 ttaacatcga tatttatact gtgaaacatg cgtttcatcc attatcaaag tatttttatc
     1801 gataataaac ttcatccaaa aacagacctt gtgcagggac ggtttctcct gcatgttgcc
     1861 gcactttgct ttcaaatatt tcatcgattg tttctatcgg catggcacct gtgccgattt
     1921 ctagtaatgt ccccatgata atccgcacca ttttatataa gaatccgtct ccgacaaaag
     1981 taaaatgaag catttctccc tttcgttcga tagataattc atcaatcgta cgcactgtgg
     2041 atttttttga ttttttcaat gcagaaaaac caatgaaatc atgtgtaccc actaattttt
     2101 cgcaagctgc attcagcttg tccatatcca actcttgagg gaaataaaag ctgtggtttc
     2161 gctcaaatgc tgaaggaatc acgttgttcc aaacataata gctgtatttt ttgcccaccg
     2221 cattatatct tgaatggaag cgctcaggca tttcttcgat tcttttgatg acaatatccc
     2281 gcggaaggta acgattcata aagtcgatca tttctgccag tccaatttct gtgtttgttt
     2341 taaaatttgc tacttgtcct cgcgcatggg tgccagcatc tgttcttcct gatccaataa
     2401 tttctatctc ttcatttgtc atctgatgca atactttttc gatttttcct tgaatggttt
     2461 tatcgtcatc tccaagtctt tgccatcctg aatatctttt tccgtcatat tcgattgtca
     2521 acttgatgtt tctcatattt tagtggctcc tctgtcttcc atttggtctt ctctctacct
     2581 ttttaagatt gtagcacaaa atatagctcc ttgcttctct aagacagaag ctatacaaga
     2641 aaactgtgga aatatatatt tcagaaaaac aaaaaacagc caccggatga agtatccgct
     2701 gactgttcaa tttgacggct caagttttac tgtttgagat gcaagatact caaccaggca
     2761 atgggcacat aattaaagaa aaaactgatt ctttggcaaa aacctatttt attcagtaat
     2821 ggccaagaat ttatagaagg aattcttgcc agtccataaa tcgccgcaaa aagcaaactg
     2881 atcacagaca gtccaaggta taagtggctt acgtccattt gcccattttt tcgatagatc
     2941 aagaaaagaa gaactggaaa caataaaaaa ccactgtaac ctaaacctga tccgatatta
     3001 tggacccatg tcgagacatt ccacgaagat tcatgggtat tgatactgaa caaacctgta
     3061 aagatacaat cacctatacc atagaacgcg atggctgctg taactagggt agctaacaca
     3121 cgagatgtac taacaaatgc agcatacaat gcaggcaatg acaggatgaa aaagatccct
     3181 gaaaccacag accaaataag aaacgctttt cttacaggac tggaaacctc tccaaataca
     3241 ctgatcacgc tcttcatttg atctaattca ggataataca atcctaatac gtacggagtc
     3301 aaaaaatcac tcagcacgcc taataataaa aagaaaaaac caaatttacg taaaaaatcc
     3361 atgatacgcc tccaataaca attacctatg cttttaattg ttattataaa cgactttatc
     3421 ttgatttaac agaaacctct atttacacga acatctatat aactcattaa aaactcgaat
     3481 cattttaaaa atactaaata tctaacgttc aacgttcact taatccatct aaacaatctt
     3541 tcaatttgat tttttcccca cttcttttac gcgcgcctag ctctcctatt gcagtaaaca
     3601 acagatcact tgacgaattt aaggcagttt ccattgaatc ctggataaca ccgataataa
     3661 atccaatacc gacgatttgc atcgcgacat cattagagat accaaacaaa ctacatgcta
     3721 atggaatcaa taacagtgaa ccgcccgcaa cacctgaagc tccacaagca gctaaagcag
     3781 acaaaataca taaaaggact ttcaaaacaa aaggtgcttc aatccctaaa gaatgtacag
     3841 cagtcaacgt catcaaggaa atggtaatcg cggcaccgcc catattgatc gtagcaccta
     3901 acgggatcga tatggaataa gactcttttg tcaatttcaa tctttcagcc aacatcatgt
     3961 ttatcgggat atttgcggca gaacttcggg taaagaaagc gggaagtgcg ctttctttca
     4021 aacaaaagaa aatcaatgga tagggatttt ctttaataaa caaaaacgtg aggaatgggt
     4081 acacaactaa tgcgacaaac agcatcgtac cgatcaaaac aagtaaaagc tgcagatact
     4141 ctgccaatcc agcgattcca gtcgtagcaa ttgattgata aaccaatcct aaaatcccta
     4201 tcggagcaaa tgcaataatc acttgtacga cttgtgacaa cgctatagat atctgatcca
     4261 ccaactcttt tgtcgattct gaacgtgctc gaaaagctag tcccaacaat acagcccaga
     4321 ataagacgcc aaggtaattc gcatcaataa gagattgaac aggattttgt gtgacattcg
     4381 tcaacatagt agataaaaca ctttccaaac tttgcggtgc tttttcagat actgtttctt
     4441 gtaaagtaat aggaacagta aaaattgaac ttacaataac tgctacaagt gcagaaagca
     4501 atgttcccac taaatataag atcaaaatag gcttcacgaa tgtcttattc ccaattttat
     4561 gcttggcaat tgacgccatc gtcaagaaaa aaaccagaat aggtgcgatt gccttcaagc
     4621 aactgacaaa caacgttccc aatattgaaa taaatgtcca tgtggggaaa aagataccaa
     4681 acaatattcc gactaaaata ccaacaacaa tacgttgaac taacgacata tccaaaaact
     4741 tctctaacaa atgaccaccc tttcacaatt ttaacaatca ttgtatcatt ttatgcaaag
     4801 aaactaaagg tataattttc taaaaattct aacaatacaa acaaccattt cttgctaatt
     4861 ttgtactttt tctgtctaca cgttgttttt tgagatattc taagttagga tgttattaat
     4921 gggcaactta tcaggaaacg ttttcttatg tttttgtcca atttttttgt gaggtgttta
     4981 ttcttgaaaa aaataaagaa ggagagttat ggcttcctga caatctttgt cgcttgtata
     5041 atgatggttt tacagcgtat attgatttca gcagtcacta ttcctacata tgcaacaaac
     5101 cctggtcgat tctacatcta tacattttta caaacttccg ttgttattgg tgcaaatttg
     5161 atcccacttt acatgggtta ccaatatcaa aaaatcgccc gtttaaaagt tttacattat
     5221 ttaagtcgtt ttgcctttat attcctaata gccacactag tttgcaatat ctttttttac
     5281 gtacaagctg gcagcttgaa tattcgtgat tattggctta tcctaacacc tatcagtcag
     5341 aattacttta cttatgctgt ttcttgtact ttgctttttt gtagtattcc ttatacagtt
     5401 ggatttttaa ataaattatc gaaaacaaca attaaatatc tactattatt tttaacaatt
     5461 ggattagttg gctgctctac tctatttaat aaagacccgt ttgcattaca gaatggacag
     5521 agtattttat ggatttttta tttattttta atgggttatg gtttgaaaga atggaactgg
     5581 aaagaaaagg tccgctataa gcttcctcaa gtatttatca gcttgattgt tttattcggt
     5641 ttgattattt tgatgacaca aatttcactc atcatcagag gaaatacaga tacagcgctg
     5701 aggttttcta aaccatattc tctcttcgca atgtattata ctttctcttc gtttttattt
     5761 ttagaaatgc tatctgataa attaggtata aaaggaagag gaaattttct tgctgtattt
     5821 ttgattgtca ctcaagttat atgtaatttc cctttagttt cttatcgcgt atctacattt
     5881 atgaaacgtg aatttccaaa ctcagggaag gcatggctga taaatatcgg gcagtttttt
     5941 atttgatatt tattagcagt gtccctccta gttatctttt tattttatat acaaaaaatc
     6001 cgtttcattc atcgtttcat cgaatacttc gcttttgatt cgattgaaca attaactcag
     6061 cgttggaaaa aaagaattca ttggcttttt gttcataaaa gttatttttt agttgcagca
     6121 tttttttact gctttacctt cgtgcagatt ttcgttttag aaccaaaaga aggttggaaa
     6181 gaaactatcc aggttgcctt aaaaatattt actcagcgac aagcacccat gatcctgaca
     6241 atcatcatta ttatgggatt tttcttctta ctattgttga tttccaatcg tttttggtac
     6301 gccttgactg ctaccttgat cattaactta ctgctcacta tttcgacagt aatcaaaatg
     6361 gaaatgcggg aagagcctgt ctttccttca gatttaaaaa tgctgaccgg attgtcagaa
     6421 ctattatcga tggttagccc agtcttatta atcgtgggcg gattgatcct tctcctatta
     6481 ttgattacta gtattattgt acaacgtaga ctacaaaaac agtattcctt gaagattcat
     6541 tggaaacgtc gatttatcag tatcgctgta ttattaggat gtttttcggg tgtctttttc
     6601 attaatcaca aaaattcgcc ttctttcttg ctgtttaatt tatttaaagt aaacaagact
     6661 ttctttaacc agcaaggcgc cgtaaaagat aacggaccag tcattcaatt cctaaacaat
     6721 atcgacatta aaatcatgga agaacctgct ggctattcga aagaaaaaat taatggaata
     6781 atgaaaaagt acaacacaaa ggcagatgaa atcaaccaaa caagaagtga ctggttaaac
     6841 aatcagacga tcgttctcaa tttaagtgaa agcttcagtg atcctgcacg tgtccctaat
     6901 ctgacagtac ctacagaccc tattccttac atcaaaagca ttataacaga aggaacagga
     6961 ggattgatgt tatccgtcgg ttatggtggc ggaacagcta acatggaatg ggaaggactg
     7021 acaggcttga gtatcagtaa cctgtctgct tcgttagtta caccttatac ccagctagtg
     7081 gagcgtcaga aaataagtcc aaatattacc gatctattcg atgaaaaaat agccatccat
     7141 ccttttacag ctgctcttta tcgcagaaaa caagtgtttg ataaatttgg ttttgacagg
     7201 ttctattatt tagacagtcc ggataaatta acttatacgg ataaaataga acaaagccca
     7261 cgcatatcgg atgattcagc atacaaagaa accttgaaag ctttacaaag caatacggaa
     7321 acgtcacaat tcatccaatt atccactatg caaaaccata tgccttatga tgattactat
     7381 agtgaattga actacactgc tgaaggaact gctgtcattc ctaatagaag aaaagaatta
     7441 caaacttata tgcaaggcct tcactatacc gatacagcag taaaaaaatt catccaagaa
     7501 atcgacaaaa tcgataaacc gattaccttt gttttttatg gtgaccattt acccgcaatc
     7561 tatagtggga atgattcgaa aaaatatgga ttagaacagc accagacaga ttatttcatt
     7621 tataacaaca agtatagtcg tgaacaagca gctacgttaa ataaagaagt tgttgctcct
     7681 aataactttg gtgctatggc tcttgagcat gcgaatatca aagtaactcc ttactatgcg
     7741 ttgttgacag aagtatctaa tcatctacct gcattaacaa ttgatcctac agaaagcttg
     7801 tctaatcgtt ttaatggaaa acaggtcttt gttacagagg atagtcaaat tatccaagaa
     7861 aaaaatttaa ctgagaaaca aaaagaaatt ctagaagatt atcgtctgat acaatatgat
     7921 cttgttgcag gtaaccagta cagtgcaaca tgggcgacac aaaaaataaa agactaacaa
     7981 ataaactgag caaggggttg tgataaaaga catgtcacaa ccccttgttt atctcattaa
     8041 tttgcttgtc cataaacgat ttgattaaag ccatttttca attcattatt cgctgtctcg
     8101 ttgaagtaaa gataattatc gggattcccc tgattttgtt gtgtcaccaa tacttttggc
     8161 tgattttgct gaaacccgaa tagatagacg tgctttttca gatatggttc tgtctctgca
     8221 tcggaataga cggctgtgat ttgatagtct gcttgacctg tcccactttc tgaccattct
     8281 gcagaaacag gcactccacc aatagccatc ttccactccc cgttcaaaat agcttgaggg
     8341 actttaagac catataagtc cacactcatt tgattcgtat aacttttgta ttgttgtccc
     8401 attgtttggc cccatttggt cataaatgcc tctaattgtg cggatttgtc tgcattccac
     8461 agtgtttgtt caacttgttc gctgctttct gaagaggaag atgaagcctc tacagaagaa
     8521 cttgaagtag atgtttgagt tgtttcagtc gttttggaag actctgacga agtagaggta
     8581 tctgctgttt ctgtacttgc tgcagttgac ttgctctctg tgctagttgt tgtagtagtt
     8641 gcaactgttg ctttcgctgt ttcttttgtt gattcttttt tcgattcatt cccgttggta
     8701 caaccagcta acaaaaaagc tagaccaatt gttactaaaa tccttttttt caattaaaaa
     8761 actcctttcg attactccca cttctttatt ctatcaaata agcaatgtga ttttattgat
     8821 ttttcgtatt ttctcatcaa tctttcaaat cttctaaaaa ctgagaagca cccgctgatg
     8881 ttgtctgtaa tacatcagcg ggtgcttctt ttattttaat cttcgtgatt ttccaattta
     8941 cctcacgctt tatatttgta tttgaagaaa catagacttt tagtcatcat cgtcttcctc
     9001 atccaaatct tgtcggacag tttttccttg gagtctttgt acttggtaga tgatttcttt
     9061 attgaaactt aaaagttcaa caagcaattg ttgcaagcca tatttttctt ctttttcagc
     9121 taatttgatt gcccgtgtga taaagacatt ttggaaatca aaatcttttg caaagttttc
     9181 caacattgtt gaggctggta aatatttgtt ttgaccatgt tcgtaaattt ttccataacg
     9241 catgacttct tctaaagtag acggaacgat ttcattttca atcactaact catgagagat
     9301 tttattgaac catctcgctt cttgatcagc atattctgaa aaaagggtac ttaattcttg
     9361 cgaagatgta cccaaaacat acaattgtgc ttggatcaat ttcatttctt ctaatttaaa
     9421 atttgctaat acatgcccca ccatggcgcc agcagttggt ttatgatggt cgatatctgc
     9481 ttgttttgtt tcttgaacaa atttttcttc cactatattc attgatttac gcctctttta
     9541 cttttgctga ttggacttca taacctaatt tttccacaac tgcagctaat tgttcagggt
     9601 ggacttcatc tggatcaaag tttgctttga ttttgctcgc attaaacaaa actttcgtat
     9661 tgcttacccc aggctgttga gaaaccgcat gttcgatttt ttgcatacag cttggacaag
     9721 ctagtgtatc taattgcata ataatttttt tcatcgtagt tcttccttcc tttttcttga
     9781 tagtcttatt ctagattaca gcttccataa aaaaattgat tcttatcaag ttttacgatt
     9841 tttcttcttt gctttcgtgt ccaaaataca ataaacgcat cgcgttaaag ataacgatca
     9901 agatactagc ttcgtgaacg aacatcccac tagccatgta aataaacccg gcaaataagc
     9961 cgttgagtaa aaataagacg acaccaatgg caatcactac attttcacgg gtatttaaaa
    10021 cagttttctt agccaagcgg taggcatgaa ccaacgattc aaaattagat tgcatcaaga
    10081 caacgtcact cgtttcgata gcaacatccg ttcctgatcc catagcaatc ccgatatcag
    10141 ccgcagccaa agagggagaa tcattgattc catctccaat aaaagcaacg cgcaatcctt
    10201 gttcttggta ttttttcaca aattgaacct tttcgtctgg taataattca gcatggactt
    10261 catcaatgcc taacatatca gctacataat cagcagtcat ctgattatca cctgtcagca
    10321 tcactaactg ttttgctcct gcttgtttca acttagctaa ttgttcagcg acttctggtc
    10381 gaatcacatc tgacacacct atgatttgag tgattttttt gtcgattgct acaataatga
    10441 ccgagctgcc tgtttgttgt aattgatgta aatcttgtac ttgctttggt gtgagagaaa
    10501 gtttgtgagc ggcaatcaat ttggtgttgc ccgcacaaac tgtatgacca tcaatctcag
    10561 ctgtgattcc ttgtcccttg attgtctgat tatctttgac tgctaattgt tgaaaatcaa
    10621 tgtctttctc ctgagcataa tggatcacgg cgcgccccag aggatgatcg gataacgttt
    10681 ctaatcgagc cactaaagct aagctgtccc cttcatcctc tgtatagttc ttgatagtgg
    10741 atacagcagt agttcctttg gtcaatgtac cagttttatc aaagacaaaa gtatcgattt
    10801 tggaaaaagt atccattgct tcaccgcctt tgactaagat gccccgtttc gctccattac
    10861 cgattcctgc tacattcgaa acaggcgcac caatgactaa agcgccagga caaccaagaa
    10921 ccaaaacagt gattgctaaa cgaaaatcac gactaatcag accaacaacc aacgcaataa
    10981 gtaaaacggt tggagtataa tactgagaaa atcgatcaat gaatttttcc gcatgggatt
    11041 tggtatcttg tgcttcttct actaattcga taattttggc aaaggtcgta tcatctccga
    11101 ccttagttgc ttcaatcgtc acgtagccat ctgctaaaat cgttccagag aagacttcat
    11161 ctccactgat tttgacgact tgtcgtgatt caccagtcac tgcggcttca tccgcatacc
    11221 ctttcccgtc aatgactcgt ccgtccacag gaatagctcc accagttttt actaagacga
    11281 tatcgccttc ttccacgtca tcgatttcca cttcttcagt cgttccatct tcttggacaa
    11341 cactagcagt agatggggcc atctcggtca aagccttgat tgactcccgc gttttggtca
    11401 atgttttttg ttccagatag ctaccaaaca aaaacaagaa tgtaacgata gctgactcct
    11461 tgtattctcc gatcataaag gcaccaagca cagcaatagt aacgagtaaa tcaattgaga
    11521 taactttgac tttcactgcc tgatacgcat ggatcataat aggtatgacc gcaataatag
    11581 aagctatggc tagagcaatg ttatagaaca agacaaaacc agtaaatttt ccgataaaac
    11641 caaaaataat caacacagct gataaggcgg tgatatgatt tcgatgctct tggatccact
    11701 tttgtaattt catctttctc cctcttttcc tttcattctt acgagactaa gtatagatac
    11761 ttatccatca taaaaaattg accactatca agtttagtca aaaaggcggt tttcttttgg
    11821 tagaatacac tacaaaaaat agttagcaag aagactcact aaaagtgatc ttgccaacta
    11881 ttgtcgtttc tatcgaaatt ttcattgaat gattttcctg tacagcatac atcggagatc
    11941 tatttcttta tctaagattt ttatcttgct aattttttcc tttagtcttt caaatccacg
    12001 tcgttcatag aattgatacg tacagccact atctgtaaaa aggaatattt cttttccttt
    12061 ctctcttttt tcaaattctg ttagcaactt ggtaccgatg ccttttgttt tcaaatcagg
    12121 atttgcagct aaaaaaatga tctctccatc tggcgaatgc ttctttaaat atgctgcaag
    12181 catttgttca tttgctgtct cgtaagctcc tttactttct ttagcaaata tattttgtaa
    12241 aaaatcgaat atcttaacat atatttgctg tccaaaagaa cgatgtttct ttttttctcc
    12301 ttttatctcc gccagcaaaa cacctgccaa ctcgtcctct gcatacaaag caagaatttg
    12361 agttgctcga ttcaactcca tatacaaaaa atatcttccg taaagattca gcagaagttc
    12421 attttccata tatctctcaa agttcattcc ttcaacagca aaatagatag cttttttgta
    12481 atctttcttt tctaagggtt taaaagttag tttcatcatt tcgcctcctc aacttcaatg
    12541 attgtgttat acttacatta taatagacac agtgtctact atctataatc aatcatctat
    12601 aagtttgtcg attaagcgac agctttgctt tgatatgtcg gataaggaga taggtaaatg
    12661 aaaaagacag atagacgcgt caaaaaaaca gaaaaagctt tggctgaaac actatccaca
    12721 ttattagtaa ataaaaagat tcaagcaatc actatacgcg aactaacaga aacggcagat
    12781 gtacatcgtt cgacttttta tacacattat aaggatatct atgatctata tgatcaatta
    12841 gaaagcaact tttttcggga tctaaatgaa attctctctt atgatccagc ccatagctat
    12901 gaggaactat acactcgctt gattgactat gtttacgcaa atactttttt atatcgctta
    12961 tttatcctca accatggtga tatttcgttt cagaagaaag ttaaacaagt tattgaagaa
    13021 aactatctga acatatggct atatgaagac aagaaaacga ttatcacaga agaaatgaga
    13081 ttctttacta cgtaccacgt ccaaggttgt ctatccgttc tcaatcggtg ggtagaaagc
    13141 aattacaagt actccaaaaa agaattatta gaactcttac agaaactgaa tgatcacata
    13201 gagaaaatca tgccttgaat aaaaacatac taagcttagt taagaagaac cgtaaccttc
    13261 tcgtataaca actgaatctt atttagccaa attgtttact gaagattttt tgagtaaaat
    13321 ttctataatt cctacttatt gaaaagtagt ttgtagtgct gcttctccct ctctaagtga
    13381 tatatcttgt tgtaccaatc aaattcacct catcattaat aaattacttt taggctaatt
    13441 tattacaact tataggttga agctgtaacc aatttatagt catattatat ttttatcatc
    13501 cagtttattg aattcttctc gtttacctca attcattttc aaggggaatc a
//
LOCUS       DAZAOD010000070        13292 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000070 DAZAOD010000000
VERSION     DAZAOD010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.072"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..2376
                     /locus_tag="ACHDPO_002021"
     CDS             4..2376
                     /locus_tag="ACHDPO_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFN3369636.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="ACHDPO_002022"
     CDS             2437..3897
                     /locus_tag="ACHDPO_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFN3369637.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="ACHDPO_002023"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="ACHDPO_002023"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFN3369638.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="ACHDPO_002024"
     CDS             6128..6277
                     /locus_tag="ACHDPO_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369639.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6352..6945
                     /locus_tag="ACHDPO_002025"
     CDS             6352..6945
                     /locus_tag="ACHDPO_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFN3369640.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="ACHDPO_002026"
     CDS             6958..7857
                     /locus_tag="ACHDPO_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFN3369641.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="ACHDPO_002027"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="ACHDPO_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFN3369642.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="ACHDPO_002028"
     CDS             8723..8983
                     /locus_tag="ACHDPO_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369643.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="ACHDPO_002029"
     CDS             9428..9634
                     /locus_tag="ACHDPO_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFN3369644.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9655..9885
                     /locus_tag="ACHDPO_002030"
     CDS             9655..9885
                     /locus_tag="ACHDPO_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369645.1"
                     /translation="MTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLVEDAPTML
                     FEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="ACHDPO_002031"
     CDS             9901..10338
                     /locus_tag="ACHDPO_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369646.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10331..11038
                     /locus_tag="ACHDPO_002032"
     CDS             10331..11038
                     /locus_tag="ACHDPO_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369647.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11202..11402
                     /locus_tag="ACHDPO_002033"
     CDS             11202..11402
                     /locus_tag="ACHDPO_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369648.1"
                     /translation="MNKIIPLLFVLCIGEILMRHGAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKLIAAIFFIGLFR"
     gene            11418..11597
                     /locus_tag="ACHDPO_002034"
     CDS             11418..11597
                     /locus_tag="ACHDPO_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369649.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11922..12185
                     /locus_tag="ACHDPO_002035"
     CDS             11922..12185
                     /locus_tag="ACHDPO_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFN3369650.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12179..12529
                     /locus_tag="ACHDPO_002036"
     CDS             12179..12529
                     /locus_tag="ACHDPO_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFN3369651.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12553..13167)
                     /locus_tag="ACHDPO_002037"
     CDS             complement(12553..13167)
                     /locus_tag="ACHDPO_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3369652.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
BASE COUNT         4917 a         2198 c         2733 g         3444 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaagaatac
      241 gtggaaaagc ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgg ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctaga
      661 ccaactgatt ctatgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacattgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaggaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaaccaat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaagg gtcttgcaaa
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggacaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg aaaaaaatac accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cataacataa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct ataccatgag acacgtgttc caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcaggtg tcgaaatgaa tctcattgcg
    10081 acgtactatc gaacactgga agaactgaaa aaacaaaatg caaaatggtt tttccaagcc
    10141 ttactatgct tggaagtagg tgtcaaacca agcactatta aaccttctga atatcaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttagatt attttgaaaa tatcaataag tatggcgcct attacaccat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggtcacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ctaaacagca aaaatgcgac gatagacgat tattatcttg tatttactag
    10801 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    10861 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    10921 cacgacttta actgattttt tagataccta cacttacgac gatacagaag aaatccaaaa
    10981 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11041 atttataccg aaaagtgaga atgtgtgaaa taagaacaaa aaccttgaaa ttaagggaat
    11101 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    11161 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    11221 tgttgttcgt actgtgtatt ggcgagatac ttatgcgtca tggtgcagct gtacatttaa
    11281 acttcgtagt attcttagga atactagtat tttgtttgat tttttggcgc tttgtgttag
    11341 cccttgtgag tctactattc aagttgattg cagccatatt tttcataggg ttatttcgat
    11401 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11461 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11521 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11581 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11641 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11701 gaaatcttta aagtatccag atcaattttt ttcttacctg attctaaaga ttttgttttc
    11761 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
    11821 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
    11881 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
    11941 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
    12001 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
    12061 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
    12121 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
    12181 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
    12241 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
    12301 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
    12361 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
    12421 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
    12481 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
    12541 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
    12601 tctcgtaaca ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc
    12661 aacgatgttt ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt
    12721 aggacgtcct ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg
    12781 tttagattcg gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt
    12841 aatgaattta tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat
    12901 gatcagctgc acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt
    12961 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag
    13021 tgcttcttga aaaacaggtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat
    13081 tctctctgca ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga
    13141 tgagacacgt atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa
    13201 acaccctaat catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg
    13261 gtatacctta tatagacaaa aactaatgat gg
//
LOCUS       DAZAOD010000071        13174 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000071 DAZAOD010000000
VERSION     DAZAOD010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.073"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            152..1075
                     /locus_tag="ACHDPO_002038"
     CDS             152..1075
                     /locus_tag="ACHDPO_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFN3369653.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            1081..2334
                     /locus_tag="ACHDPO_002039"
     CDS             1081..2334
                     /locus_tag="ACHDPO_002039"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFN3369654.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            2468..3814
                     /gene="gor"
                     /locus_tag="ACHDPO_002040"
     CDS             2468..3814
                     /gene="gor"
                     /locus_tag="ACHDPO_002040"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFN3369655.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGIGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(4628..5581)
                     /gene="menA"
                     /locus_tag="ACHDPO_002041"
     CDS             complement(4628..5581)
                     /gene="menA"
                     /locus_tag="ACHDPO_002041"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFN3369656.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(5594..6697)
                     /locus_tag="ACHDPO_002042"
     CDS             complement(5594..6697)
                     /locus_tag="ACHDPO_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFN3369657.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(6787..7722)
                     /gene="pplA"
                     /locus_tag="ACHDPO_002043"
     CDS             complement(6787..7722)
                     /gene="pplA"
                     /locus_tag="ACHDPO_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFN3369658.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            8024..9958
                     /locus_tag="ACHDPO_002044"
     CDS             8024..9958
                     /locus_tag="ACHDPO_002044"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFN3369659.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            10415..10831
                     /locus_tag="ACHDPO_002045"
     CDS             10415..10831
                     /locus_tag="ACHDPO_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFN3369660.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            10845..11411
                     /locus_tag="ACHDPO_002046"
     CDS             10845..11411
                     /locus_tag="ACHDPO_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFN3369661.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            11434..12420
                     /locus_tag="ACHDPO_002047"
     CDS             11434..12420
                     /locus_tag="ACHDPO_002047"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFN3369662.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(12575..>13174)
                     /gene="scm"
                     /locus_tag="ACHDPO_002048"
     CDS             complement(12575..>13174)
                     /gene="scm"
                     /locus_tag="ACHDPO_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFN3369663.1"
                     /translation="TSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTD
                     TSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDT
                     SSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKS
                     KRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         4087 a         2392 c         2730 g         3965 t
ORIGIN      
        1 tcacaatctc tttttatatt tggacagaat atatcgaact ttattttgat tttttgtgaa
       61 ataattttca aaaatccgac tttaaataga agaagtattg gaaagttttt agagctatgc
      121 tactattatg aagttgtagg aggagaaaat tatgatcgaa ctcataacca cagtagaaac
      181 tattgaacaa gcagaacagt tgcttgctgc aggtgcagat acactatatt tcggtgaaga
      241 gcaatttgga ttgcgtctgc ctgcttcatt tacacgagaa gaacagcgac aattggtaga
      301 attagcacac aagtatggta aaaaagcgaa tattgctgta aatgggatca ttcatcctga
      361 aaaaatgaaa aatgtacctg aatatttggc ttttttaaaa gaaataaacg tagatgtgat
      421 cacagttggt gatacaggta ttatttatac gatgaaaaaa aatcctgaat tgcgtatacc
      481 gtatatttat gatgctgaaa cattagtaac gagcgcacgt caaatcaatt tctgggcgaa
      541 aaaaggcgca gttggagcag tacttgctcg tgaagttcct tttgaagaga tgaaggcgat
      601 ggaagaaaaa ctcgatattc ctgtagaaac ccttgtgtat ggtgctacat gcatccatca
      661 atccaaacgt ccactgctac agaattacta taactatacg aaacaagacg aacaaaaaga
      721 tcgtgaaaga ggtcttttta tctcggaacc taaaaaagaa gagacacatt attctattta
      781 tgaagatagt catggcacac atatttttgc cagcaatgat ctgaatctct cgaatgaatt
      841 gaatgaactt tatcagcatc attactgtac atggaaattg gacggattat ttactccagg
      901 cgaaaaattc gtaaacatca ctcgactatt cgccgaagca aaaaaacaaa ttttagaagg
      961 tagctgggat caagaaaaag cggaaaaaat gactagcgaa atcagtaaat tgcatcctga
     1021 aaaccgtgaa ttagatacag gattctttta tattgatcct tctgctatca aataaggagt
     1081 atgatgaaag aaatgacagt aaaaagaaaa ttgaaacgac cagaaatcct agcgccagca
     1141 ggaacactgg aaaagttaaa aaccgcgatc cattatggag cagatgcagt atatattggc
     1201 gggaatgcat atggtttaag aagccgtgca ggtaatttta cttatgaaga aatggctgaa
     1261 ggagttgctt ttgcaaaaga acatgatgcg aaggtatacg ttgctgctaa tatggtcacc
     1321 catgaaggaa atgaagatgg agcaggggaa tttttccgca gtttgcgtga tgtcggtatt
     1381 tctgcagtga ttgtttctga tccagctttg atcgaaattt gtgcgacaga agccccaggt
     1441 ctgccgatcc atttatccac tcaagcttca gcaactaatt ttgagacatt ggaattctgg
     1501 aaagaagaag ggttggaacg tgtcgtttta gctcgtgaag tttcaatgga ggaagtggca
     1561 gagattcgta aaaatacgga taccgaaatc gaagcattta tccatggtgc catgtgtatc
     1621 tcttattctg gtcgatgcac attgtccaac catatgtcga tgcgggatgc aaaccgtggc
     1681 ggatgttctc aatcttgtcg ctggaagtat ggattgttcg atatgccttt tggtcaagaa
     1741 cgaaacagtt taactgatac aggcgaagtg gaagaagaat tctcgatgag tgcagtggat
     1801 atgtcaatga tcgaacatat tccagaattg attgaaaacg gcgtagacag cttcaagatc
     1861 gaaggaagaa tgaaatcgat ccattatgta tctacggtgt caaatgtcta taaagcggct
     1921 gtagacagtt atatggaaga tcctgaaaac tatgtctgca agcaagaatg gatcgacgag
     1981 ttatggaaag tagcacaacg agaattagct acaggttttt actacaatac accaactgaa
     2041 aacgaacaat tattcggtga acgtcgtaaa atcccagtat ataaatttgt cggtgaagta
     2101 ttatcttatg atgaggcaac acagattgct acgatacgtc agagaaactt gttttctgta
     2161 ggagatgaaa tcgaatttta tggtccagga ttcagtcatt tcagtcaaac cgttgaagtt
     2221 atgcataatg aagaaggcga atccattgac cgagcaccaa atccaatgat gattttaact
     2281 atgccagtcg cacagccggt gaaacctgga gatatgatcc gaaaacgtaa ataaggaaaa
     2341 agctgatata tccctgtttt aagcatcttc gcatacaaaa ttcaagaaaa gtgttacact
     2401 tgttttctgt agaaaaagga tcgttaaata aaggttttga ttgatctctt caataaggag
     2461 gaacaaaatg caaatatatg attacatcgt aattggtggc ggctctggcg gtattgcttc
     2521 agcaaacaga gcagggatgc atggcgcaaa agttttgctg attgaagcga atgaattggg
     2581 cggaacatgt gtcaacgtcg gttgtgtacc taaaaaagtt atgtggcaag caagtacgat
     2641 tttggaaaca attgaacgag atgcctcaag ttacggtatc caagcagatt taaaaaatgt
     2701 tgatttcgcc ggtctagtag aaagacgaga aaaatatatt gattttctac acggtgctta
     2761 tcaaagagga ttagatagca atcatgtcga ggctataaaa ggttacgcta cttttatcga
     2821 tagtcaaacg atcgaagtaa acggtgaaac ctatcgtgct cctaaaatct tgatcgctac
     2881 tggaggccgt gcaagtaaaa tgaccattcc tggtggagaa tacgcaattg attcaaatgg
     2941 attttttgaa ttaacagagt tacctaagag agcaatcgtt ttaggtgctg gatacattgc
     3001 ggctgaactt tcaggtgtat ttcgtggttt aggtagtgaa gtcatgtggg catatcgaaa
     3061 agaacgacca cttagaacgt ttgataaaat gctttcggac aatttgatcc aaatgtacca
     3121 agaagctgga ataaaaactt acgcacatca tattgctaaa gaaattacta aaaacaatga
     3181 cgaatatacg gtgctatttg aaaatggtga aaccttaact ggtgattgtg tactttttgc
     3241 cggtggacgt gtaccgaata ccgaaaaatt aggtctggaa aatacaaatg tggaattgga
     3301 caaaaaaggg tttatcaaag tagataaata ccaaaataca acggatgaac atatttttgc
     3361 tgttggtgat gtgatcggta aattagatct gactcctgtt gcaatcgcag ctggtagacg
     3421 tttatcagaa cgtttattta atggaaagaa agattcttat cttgactata aacttgttcc
     3481 gacagtcgtc tttacgcatc caccaattgc aacaattggt ttgacagaag aagaagcatt
     3541 ggaaaaatat ggcgaaaatg aattgaaagt ttatcgttca cgctttaccc caatgtactt
     3601 tgcattaaat gattatcgcc aaaaatgcga aatgaaattg atctgtgtcg gaaaagaaga
     3661 aagaatcgtc ggcttacatg ctattggtat tggtgtcgat gagatgctgc aaggttttgc
     3721 cgtggctatc aagatgggtg caactaaaga agactttgac aatacagtag ccatccatcc
     3781 aacaggagcg gaagaattcg taacgatgcg ataatttaat attaacagtt ccaacagctt
     3841 tttattgaac aaaccatgta aaaccagaaa atcagtatac tgattttctg gttttttgtt
     3901 ttttagttat ttatgtaaga ttgcttcgat aattctcaaa acgaaataag tagggaagtt
     3961 ggagattttg attatcttcg taactgacga agagtaaatg aatccatttg gtatgcactc
     4021 ttaagttcaa aatattggta tcgatgttta aaagaaatag aaatgtatcg aagaacagat
     4081 gtttaaaaaa gtgtgacttt gtataaataa attagaagaa gcaaacgagg atgttaaaag
     4141 aataccatat agttaccaaa ccaagaaagt tctcgtcaag ttcgctggta cgaatcaaat
     4201 caagtgaaaa aagggactgt gaaaaaaatt gtgtcatagt tagtcacttt ttccgaacaa
     4261 atagtgttca atcagctgtc cttcggtatt agctcaaaaa acggcaaaat atgaggaact
     4321 atttttccat ttgtttctct aatactcagg acaaaacact gattttacaa cctctgataa
     4381 acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa tgtggaaagc
     4441 cattttcaca aaatttttct taatactcga aactaagcga ctttttcaca acctcctgat
     4501 aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa aaatataagg
     4561 agctattttt atttggctgt tcttattact tgatgcaggg cagttttttc acaacctctt
     4621 catgctgtta aatggcttgc ataatgattg ttagtaatag ccccaataca taactggcat
     4681 tgaataagac catatttttg atggaatagc tgaaactgat aggctggggt aacgtttgct
     4741 tgaattgatc caaatgcttc ttcacaattg gcaaggtcaa gaaggtgacc aagatcggcc
     4801 attcatagat accgctcaac aaccccatta aaatcacgaa atagcaagca tacatcaata
     4861 gctggaataa gactgttccc gcaggacgtc cgatataaaa aactagtgta tagcgatgat
     4921 tttcaatatc acggtcaaga tcccgcaaat tattagccaa catgatattg gcaatcgtaa
     4981 acaccaaggg taaggaagct aatacgattg ctgctatagc ccaaagattt cctaccaaag
     5041 caaattgtcc agatgaaaag ttgactgtca gatcatagac atctgaaccg aatgtattga
     5101 cataaacgac catggcaaaa attccaaggc ccatagtcac cccactgaaa atttccccta
     5161 aaggcattcg agataaagga atcggtccga atgtatagaa tactccaata aaacaacaga
     5221 taaatcccat caaaagtaaa agccaacccg tattgatcgt tagaataacg ccgataacaa
     5281 aaacaaatgc aatcatagct aaaatcatgt ttcgaatcaa tacaggagat agatttctgc
     5341 ggccaatgac attttcttca tacttatata cttcagaatg agccttttca taatccatgt
     5401 aattattgat agcggtagtc gctaaatcaa aaactagcat tccaataaaa aataaaaaag
     5461 tgtttagcca atgtatctca tgaaaaaaag cgatagagaa taatacccct accgcaaaag
     5521 gaaatacact agccaccttt gttcgtattt caactacttc taaaaagatt tttagtgtca
     5581 tggttcgtac tccttatttt agttcagaac ggtcacccat cgtgtaatgg gagtcctccg
     5641 ataatttgaa ggtgtctttg attggatcgg tcacatatac tttatcgtct tttgtcacga
     5701 agatcgcttc cgtcccgtta ttcaattcgc tttcgacgta ttccagtcct tttttcacac
     5761 ccattgaaaa gactgctgta gacaacccgt caccatcaat tgatttatct gttatgatcg
     5821 tgacacttgc gatatcattg tcgaacggat aacccgtttt tggatcaaac aaatgatggt
     5881 attttttgcc atctacttct aaataacgct cgtaaattcc agaggtaact aatgttttgt
     5941 tccgttcttt aatagaacct aaaacagatc cgcgagccat gttcggatct tggatgccga
     6001 ctgtccagtc ttggttttcg cctcttgggc tgtggcctaa gacatagaca ttaccgccca
     6061 agtcaacgat ggcagtggtc actccttgtt ttttcaagac tttcactact tcgtccgtaa
     6121 tgtaaccttt ggcgattgca cctaaatcga tgatcattcc tttttctttt agataaacag
     6181 ttttttcttt gtcatttagt tcgatcttat gataatccac taatttcaat gcctgatcga
     6241 tttcttcttg ggaaggtttt ctggcgtcat caaaaccgat tcgccataat tgtgtgattg
     6301 caccaatcgc catatcgaat ccgccttgag aatcttggct atattcgtag gcccgcttga
     6361 ctaacgtgta gacgtcatca gaaactttta ctggtttgat cccagcttgc tcattcactt
     6421 catcgatctc agaacctttt tgattgatcg tgattttatc accaagttct tttactcgat
     6481 cgaaggcagg tttcaatgct gattctttgc cttcatcata cacacggata cgaacgtaag
     6541 tccctaacaa gaactgttca tcagaatatg gatctttcaa tatcttggta gctgctgaac
     6601 tttcagtggt tgttttattt gctgagttgc tgcagccagt tagcaccata aaagagatgc
     6661 ccagtgtgat taaggaaaat agtagttttt tccgcatctt tttcctctct tcattttgaa
     6721 aggtgagacg actgcctaat ctggctatcg tcccaccctc caacttttat tagtatgatt
     6781 atgtgattat ttttctgtta cgatattatc tacttcgatt gtttgagtgt cgcctttttc
     6841 agctgcattc actaattgtt gtgcgtacat gatgaatgaa tgtgagctgt gtgtagcacc
     6901 tgtaacaact tctacattag caggtgagcc atcttcttcg cccattgctt tgacgaattc
     6961 gtcgttcaga gtagggatgt aagtttttgg ttctgtaccg ctttttgctt tcatattttc
     7021 attatattct gtatcatctt gttttgattt accgtctttg tcgatataat caaagtttga
     7081 ttcagttact ttgccgccag caactgtcat ttcgaattgc acacggtagc cgttagagta
     7141 gttcttttct tcaagcttgt aagtgccgtc tttcaaatca gcaccattgt cgatttcgat
     7201 tgtatctgtg ttaccagctt gagcagcttg gatcaattgt tgtgcgtagt tttggaagct
     7261 ttcagatgag tgagtagctc cagttacgac ttccacaccg cttgcgcttt gtgcttttaa
     7321 gaattggtca ttcaactcag gaatgtattt ttctgggttt gtgccagatt ttgcttccat
     7381 gtttttgttg tattctgcat cttttgtttt tgattcgccg ttttcattga cgttatcata
     7441 ttttgattca gtgattttgc cgtcttttac aaccatttca aagactgcac ggtaaccatt
     7501 tgaataattt ttttcttcta atttatatgt gccgtcttgc aaatctccgc cagctacaac
     7561 ttttgcagat gattctgttg tgctttttgc agtcgaagat tgtgctgtag atgattcaga
     7621 agaagagttt gagcttccgt tgtcatctgc gccgcaagcg cctaacacta gagctgaaaa
     7681 tgctaatacg gcaaatccag ttacaaaacg ttttttcttc attttaatac cccaccattc
     7741 catttctagt ccacaatttt tctttgtgat tcattataca ttctaatctt tttagcctat
     7801 aagtcaacta tttttgataa ataacccatg taatatttca aacgttttct ttcagcaaat
     7861 ttcgtgaaaa aacgctttat tttaaaattt gaaaaaaatc caaaaggagt tagacaaaag
     7921 aacagaacat ctatataata tatggagatt gtgtaataag tatcaaacta aaagaattat
     7981 catatattca ttatatagat agtctataag gagcggatga tcaatggcaa agcaaaatat
     8041 tgtcgttgta ggagcaggat atgccggtgt ttcagctaca aaatacttgg caaagaaact
     8101 gaaaaaagaa gatgtagcaa ttactctgat cgatcgtcat tcgtaccata ctatgatgac
     8161 cgagttgcat gaagtagctg gcggacgtgt agaaccagaa gcaatccaat acgatctgca
     8221 gcatttgttt gctcgtcaaa agaatgtaca acttgtcaca gacactgtaa tcggtatcga
     8281 taaagaacga aaaatcgtca agaccaaatt aggttcctat ccttttgatc agctgatcct
     8341 tggaatgggc ggagagccga atgactttgg tacacctggt gtcaaagcac acggattcac
     8401 cctttggtca tttgaagatt ctgtaaggat tcgggaacat attgagaaga cagtagcaaa
     8461 agctgcattg gaaccagatg atgaactgcg taaagccatg ctgactttcg ttgtctgtgg
     8521 ttctggattt accggtattg aaatgattgg ggaactgatc gactggaaaa atcgcctagc
     8581 caaagattat aaattagatc caaacgaaat cacactgatg gtcgtagagg caatgccgac
     8641 gatcttgaat atgttggatc gaaatgatgc tgcaaaagct gaacgctatt tgcgtaagca
     8701 caacgtggaa ttattattga atgcaccaat cgtagaagtg gctgctgatc atatcaaatt
     8761 gaaagacgga cgcaacattc cgactcacac actgatttgg acagctggtg tcaaaggaac
     8821 ttctgacgct gctgactttg gattagaatc agcacgcgga cagcggttga tcgccaatga
     8881 atatatgcag gcaaaaggct acgaagataa aaacatctat atcattggtg atttagtctt
     8941 ttatgaagaa ttcccaggaa caccgacacc gcagatcgtt caagctgctg aacaaacagg
     9001 acacacagcc gcagcgaata tcgtggcttc gatcaaaggc ggagaaaagc ataaatttaa
     9061 aggaaactat caaggattta tggtttctat tggtgccaaa tggggggtag ctaacctatt
     9121 tgataagatc catttaagcg gatttttagc tatcgtaatg aaacatatcg tgaatttgaa
     9181 atacttcttt gatattcgtt ctggttatta tatgttccaa tatttaatgc atgagttttt
     9241 ccatatcaaa gatgatcgca acgtgactcg aggacattct tctcgttacg gcaatgtctt
     9301 atggagtgtg ccacttcgta ttttctatgg tttagtttgg ttcgttgaag cttccaaaaa
     9361 aatcattggg aatggtgaag tgttcaaacc aagtacttgg tttggtgaag gatcatggtt
     9421 cactggaaac agtgtgttcc cttggacatg ggaatacaat gtaacagatg ttgccagtgg
     9481 tgcttctgct gctggtgatg caaccacagc tgccagcgga gcaggggcaa gtgccggaga
     9541 agcagcgact caagctgcac attttggttt gagttatgca tacggtgaag aaccaatggc
     9601 tgtgattgag aagtcaccag actggttcac aaagatcatg caagtgatca tgccaaacaa
     9661 tgatgtagca atgttcttcc aaaaattcat ggtattcttt gaaattgcct tggcattagc
     9721 attgattgct ggattattca catggctatg cagtgcgaca acgattgtat tggtgatcac
     9781 gttctgctta tcaggcatgt tttactgggt aaacatttgg ttcatttttg ttgctttcgc
     9841 attgatgaac ggttccggac gtgcgattgg gttggatcgc tgggtaattc catggctaca
     9901 acgtacacta ggtaattggt ggtacggtag accaagttcc cagtacggca agaaataaat
     9961 agataaagaa cgttatttga atgcaagatt tcaatagaaa ggggctgaga caaaccgtca
    10021 cagcctcctt tttatgtaaa attaaaggaa taagatgccc gagataagcc tccatgagca
    10081 agacacaggt gtcacaacct ctgttacaac ctcttgttat aaacggtgtt ccagaagtag
    10141 cttcttcgaa aaataagccg aaatttcaca aaaacttgaa aagtaatttt cgtaaattcc
    10201 ttcttatttc ttgaagttgc ccacttctgt cacaacctct tgttataaac ggtgttccac
    10261 ctgctgcttc tcggtaataa gcccaaagaa ttagaaaaca tggaaagctg ttttctattc
    10321 ttcgttctta ttactcaaag caagacacag gtgtcacaac ctcttgtttt tatgctaaaa
    10381 ttgggtgagt taatctggaa aaaggagaac aaaaatgagc cttaaagaat ttgctgaaaa
    10441 aagtctgctc aaaccttggg atgtttttat tattttgctt ttgactgttc tttctttttt
    10501 accagtcatg atttttggtc ttcagcaaaa caccgcaaca gcagaaaaag aagcggtact
    10561 gcgtgtggat ggcacagaaa tcaaaacatt ccctttgatg gctggagaag agagcaacac
    10621 atatacttac aaagatgaac acggagatta taacttgatc gagatagatg gcgatcgagt
    10681 acggataaaa gaagcagatt gcgatgacca gatctgcgta cgtcgaggct gggcaacgaa
    10741 aaatggcgaa accatcgtct gtttgccaca taaattagtg atcgaagtcc gttcaacaga
    10801 tggaggtgac gaagacagtc tgatttatta gaccttcaca caccatgagt aaattacaaa
    10861 aaatgattta tatttcgcta cttgttgcac aaggagtgat cattggttta ttggaaaata
    10921 tgatccctta tcctttttct tttgcgcctg gtgcaaaact aggcttagcc aatctaatca
    10981 cgatcgttgc catttttacc atgaaaaaac gagacagctt cttactactt tggctacgac
    11041 tattcctgac tactttgcta ggcggaacga tttccacatt cctttatagt atgagtggtg
    11101 ctttgcttag ttattttgga atgttattgg tcaagcaatt aggaccaaaa cgtgtcagta
    11161 tcatcggaat tagtgcggcc ggcggtttca tgcataatgt cggacagctt ttgatggctt
    11221 ctttcattgc acaatcatgg acagtcatgt tgtacttgcc agtcctttca gttttaggga
    11281 ttttatcagg gattgcaatc gggatcgcag cgaattatct tttacgacat gtgcagacac
    11341 ttcaacgatt ccaaaaagat tatgagcagg gaaccaaaca aaaatggagc ccaatgttta
    11401 ccaaaaaata atcgtcacac aaggagtttt tttatgaagc tacatccaat gtgggaaaac
    11461 tatcctgctt taagtaaaga attgacagaa acactaaaac ggatggaaga aactgtccgc
    11521 ctgaaaaaca aacctgtcga acaagcaatc aaagaaacga tccatgccgg cggaaagctg
    11581 ttgcgtcctg cctatcagct attgttctca caatttggac cagagcaaga tcgagacaaa
    11641 gccatcgctt tggcagcttc tatcgaaatg ctccatacgg ccacactgat ccatgatgat
    11701 atcgttgatg aagcggatct gcgacgtggt cagcctaata tccgtagtca gtttggtaat
    11761 gtcgtttctg tctatgcagg agactattta tttgtctgct gttttaaact attgtctgat
    11821 tactccactt ccttgaaaag tctccaattg aattctcgca gtatggaaaa agtattgaat
    11881 ggcgaattag ggcagatgga tgatcgctat aattatgaac tttctgtaaa agaatatttg
    11941 gaaaatattt caggtaagac agctgaactg ttccaattaa gttgttctgt tggcgctttt
    12001 gaaagtggaa caagcgagcg cttcgcaaaa aaagcaggag atatcggact ttctatcggg
    12061 atggcctttc agattatcga tgatatttta gattatacaa aagagagcca ggaaatcggc
    12121 aaacctgtac tagaagacat gcgtcaaggg gtctattctt taccgttgat ctactctttg
    12181 caaaaaaaca aaccaaagct actaccttat ttagagaaga aagcggcaat gacagaagaa
    12241 gatgtcgacg ccgtacgcaa aatcgttgaa catacaggag gcgtggaaga agctaggaag
    12301 ttagcggcct cttacacaga aaaggctttg aaggaaataa agaaattacc tgccacctct
    12361 cttcgaacaa aagagaatct cttttccctt acccaactga ttttggatcg caaagactga
    12421 atagggaaag gttcgatacg taaataaatt tctcagaagg aaatctacgt gttttttgac
    12481 aaattgaatt gtagttcttg tatttatgat aaaaagcaaa aataaagagc aacgtccgtt
    12541 agcgacgttg ctctttttta tcttgaatat ttttttacct tttcgatttc ttataactca
    12601 taaaagtgat tcttaaaccg attacaagta atataacgcc tgcgagtgtt atccaattat
    12661 tcgattgact tccagtttta ggaagtgctc tttttgattt gtttccattg tcattgcttg
    12721 ttttattagt taagttaaag ttcgtcctgt tatccgaact tgtttttgag aaggagacac
    12781 ttgcatgacg tgtatcgctt gtggtagacg acgtgtctgt actatcgctt gaagttgatg
    12841 aatctgagct atcacttgtg gtagaggatg tatctgtact gtcacttgaa gctgacgtgt
    12901 ccgtgctatc acttgtagtg gtagatgaat ctgagctatc acttgtggta gaggtagtat
    12961 ctgtactgtc acttgaagct gacgtgtccg tgctatcact tgttgtggta gatgtatccg
    13021 tactgtcgct tgaagctgac gtgtccgtgc tatcacttgt ggtagaggta gtatctgtac
    13081 tgtcacttga agctgatgtg tccgtgctat cacttgtggt agaggtagta tctgtactgt
    13141 cgcttgaagc tgacgtgtcc gtgctgtcac ttgt
//
LOCUS       DAZAOD010000072        13086 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000072 DAZAOD010000000
VERSION     DAZAOD010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.074"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(79..2199)
                     /locus_tag="ACHDPO_002049"
     CDS             complement(79..2199)
                     /locus_tag="ACHDPO_002049"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFN3369664.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2429..3607
                     /locus_tag="ACHDPO_002050"
     CDS             2429..3607
                     /locus_tag="ACHDPO_002050"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFN3369665.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3623..4381
                     /gene="aroD"
                     /locus_tag="ACHDPO_002051"
     CDS             3623..4381
                     /gene="aroD"
                     /locus_tag="ACHDPO_002051"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFN3369666.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4404..4889
                     /gene="ybaK"
                     /locus_tag="ACHDPO_002052"
     CDS             4404..4889
                     /gene="ybaK"
                     /locus_tag="ACHDPO_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFN3369667.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4960..6213)
                     /locus_tag="ACHDPO_002053"
     CDS             complement(4960..6213)
                     /locus_tag="ACHDPO_002053"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFN3369668.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6329..7678
                     /gene="gdhA"
                     /locus_tag="ACHDPO_002054"
     CDS             6329..7678
                     /gene="gdhA"
                     /locus_tag="ACHDPO_002054"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFN3369669.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7790..9136
                     /locus_tag="ACHDPO_002055"
     CDS             7790..9136
                     /locus_tag="ACHDPO_002055"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFN3369670.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9444..9830)
                     /locus_tag="ACHDPO_002056"
     CDS             complement(9444..9830)
                     /locus_tag="ACHDPO_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFN3369671.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10098..10247)
                     /locus_tag="ACHDPO_002057"
     CDS             complement(10098..10247)
                     /locus_tag="ACHDPO_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369672.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10709..10921
                     /locus_tag="ACHDPO_002058"
     CDS             10709..10921
                     /locus_tag="ACHDPO_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369673.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11199..12998)
                     /locus_tag="ACHDPO_002059"
     CDS             complement(11199..12998)
                     /locus_tag="ACHDPO_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFN3369674.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2354 c         2577 g         3864 t
ORIGIN      
        1 ttattctaag atttctcttt accaacatca tttgacaaag agcctaattt tgtcgctgct
       61 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
      121 cgtttgcgtt ttataaagat caacagttga ttgtcccttg tgttcactaa agacactagt
      181 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
      241 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
      301 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
      361 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
      421 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
      481 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
      541 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
      601 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
      661 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
      721 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
      781 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
      841 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
      901 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
      961 ttgcagacgt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     1021 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     1081 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     1141 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     1201 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     1261 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     1321 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcaagctgga gaccattctc
     1381 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     1441 attttttcct ttagcgagcc cgaacaaatc atcatttggt gctgcataat gttcttttac
     1501 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     1561 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     1621 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     1681 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     1741 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     1801 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     1861 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     1921 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     1981 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     2041 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     2101 taaataggca aaaatcgttt tcaaccaaag taaaacaact agtaaagaaa aaaatccgag
     2161 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     2221 tcttaatcac agaagtgtca tgaaaccatg ttacacagct cacttattct catttatttt
     2281 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     2341 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     2401 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     2461 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     2521 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     2581 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     2641 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     2701 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     2761 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     2821 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcgtag gaggctatga
     2881 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     2941 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     3001 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     3061 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     3121 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     3181 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     3241 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     3301 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     3361 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     3421 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     3481 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     3541 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     3601 ccattagaag gagcgatgca gaatggtttg ggtaaaggga ttgaatatag gaagcggtag
     3661 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     3721 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     3781 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     3841 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     3901 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     3961 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     4021 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
     4081 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
     4141 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
     4201 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggctgg
     4261 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
     4321 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
     4381 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
     4441 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
     4501 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcat atatttaaaa
     4561 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
     4621 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
     4681 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
     4741 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
     4801 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
     4861 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
     4921 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
     4981 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
     5041 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
     5101 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
     5161 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
     5221 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
     5281 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
     5341 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
     5401 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
     5461 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
     5521 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
     5581 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
     5641 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
     5701 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
     5761 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
     5821 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
     5881 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
     5941 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
     6001 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
     6061 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
     6121 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
     6181 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
     6241 atctgaagaa agaaaacaga aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
     6301 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
     6361 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
     6421 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
     6481 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
     6541 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
     6601 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
     6661 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
     6721 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
     6781 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
     6841 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
     6901 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
     6961 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
     7021 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
     7081 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
     7141 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
     7201 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
     7261 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
     7321 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
     7381 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
     7441 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgcccagcg
     7501 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
     7561 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
     7621 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
     7681 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
     7741 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
     7801 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
     7861 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
     7921 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
     7981 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
     8041 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
     8101 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
     8161 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
     8221 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
     8281 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
     8341 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
     8401 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
     8461 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
     8521 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
     8581 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
     8641 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
     8701 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
     8761 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
     8821 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
     8881 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
     8941 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
     9001 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
     9061 caagaaaaac atgttcgcac ttctaggcaa accgggcttt gaagatcttg ctaaagaatt
     9121 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
     9181 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
     9241 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
     9301 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
     9361 ggttaattct gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg
     9421 cttttttgcg atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt
     9481 accttatcgc tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc
     9541 aagatcgttc cttcggtgta agcagaacca ttggcagagt caccagaagt aatgacatcg
     9601 aaatctaact gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct
     9661 cttccaatta cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg
     9721 actaccgcat aataatcttt acctacataa gtagactgat agtagtccca acctttccat
     9781 cctataaaag caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc
     9841 cttttttatt tttattatat taaatattat acagataata acggaatatt atcatcgaaa
     9901 cagctaacaa aattgtcata aaaaacgaga tggttgatat tagaacttgt gtttttgttt
     9961 aggtctagag ataaagagag acaatttcca aatatatgta atgaatacaa aaagacgttt
    10021 gtcgcggatt accgttacaa acgtctttta ttgattttcc gagatctcat cagtcgccat
    10081 ttggaatggt tcactcctta tctagattcg tttaatgctc ggactgcttg ttcgattgta
    10141 ataccaaacg caacgttatt ttcgttttgt gcatcaatcg ccataaaacg gttagaagtt
    10201 gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa acgtcataaa attcatctcc
    10261 tttgtaatgt aatttagttc ttgaaagttt cctttaaact ttcgaactta taccaagttt
    10321 agcatcgtac gttttttgat gcaattaaaa agcatttatc attttcctta tttatttttt
    10381 cttaaatggt ttagctattt tcttttaatc cgataagtag cccaatcatc aaggttacaa
    10441 atactattgc ttgaatataa atcatatgct cacctcttta taaataactt agcaatataa
    10501 agaaaaaaac gcacgaacaa cataggaata taaacaaacg tttttgtcac aacgtctaag
    10561 atcgtgttaa aaaatagtta tctaaaaagc agaaagatac tcaaaataaa aaataaaaaa
    10621 atgaataaaa acgttttcaa atacaaggta atttgttatt ataaaataaa gaaaaaacaa
    10681 aataaaaata aagaaaagag ggaatgaaat ggtaaaagca gaagtaggaa gatcttatat
    10741 atgcaaaccg atcggagtat ctcatgaact aatcggctgt attgaacgta catatatcaa
    10801 cacggctgtc gtgtatgttg aaagttatga ccaacgagac tatcaactta tcaatgaaag
    10861 caagtatcgc atgctcgtaa aattctgtga tattagcgca cctactgaat tggtttctta
    10921 aacagtattt ttgagaattc gcaagaactc ccttataata taaataaaga cagaagggag
    10981 cgagaagata tgccaaaaag aaaaagttca gggaaaatgg gaattattct tgcagtgatc
    11041 tctgcaattc ctgctatttt agctattgtt cgtgcgatga aggaatcaag agaaagttaa
    11101 gcacacatta tgagcgtcaa acaaaaaacg catatacctg cggtggcagg ttatgcgttt
    11161 tttgttgtat aaagactttt ttcattaacg atttttgatt agccgactcc caaaacaaaa
    11221 tttagcagtt tatctgaata agtgatttct tcatctgttt gtttcacact ttcatttagt
    11281 agtcccatct catcggttat gataccatcc acaccataaa acatcatgcg actcatggca
    11341 tctgaatcgt tgattgtcca tacatatact tcttttccgt cttggtgggc agaattaatg
    11401 aagttacggt tgatcgtact atattccatt gtcagaaaat cagcaggcgt cacagggggc
    11461 ccaacaatat tgaaaggtaa gatgtagccc acataaaagt ttggttctgc ttcttttaaa
    11521 tctgaaacgg tttggtacgt caaactttgc aaaatatgat ggttctctaa gataactttg
    11581 cggtatttat ggacaaatcg ttcgacaagg tcatccgaat cttttttaga ggtcttgatc
    11641 tcaataagta atttttggtt tagcttatgt gctttttcca aataagaatc aaaagaacaa
    11701 acaggggctt gcactccgtt ttcagtaact gtaagatttg tcaattcttt caatgtaaga
    11761 tcctgtggtg ttccatttac ccctgttaag tgacgaagat ttgcatcatg catcactacg
    11821 aaatgaccat cttttgtttc ctgaacatcc atctctacat aatcaggatg atagtctctg
    11881 cttgtttttt caagtgcttc taaagtattt tgcgccccat tttgggtact cacacctctg
    11941 tgagagacag tcactggttt tgtctgaaca gctgaagtca gataatccat attgtaaaga
    12001 cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac cagtgttttt cagcgcagag
    12061 aaacgcaagt tgggggcttg tgggataaac cacttaggga tctcaggcaa gaagccttcg
    12121 tcatccatga aatcaacaat gatataaaaa atccctacgg tagacatcac gatattgaat
    12181 aataaaatcc cttgtaaaag cgtcatagca aacacagcgc tgatcaatgc atagtctggg
    12241 aaaaattgtt caaccatact ttgtgccaaa ataacaacga tatatcctaa agaagaaagg
    12301 agtaaaatcg taccgccaat cacaataaat tggcccgtga tggccaaaag acgcgatttg
    12361 gtcaatgacc agctttcccg aatggctgct cgaaaagaac gatctcgtag aatcatttcc
    12421 ggtaaagcaa aaatcagtcg aatcccaata tagccaagga aaatataaac gagtaaaaag
    12481 gaactgacga tgatccaacg attagcaaaa ataaaatcca taatgaaagc ggggattttt
    12541 atttttgaca gtagatcaga attaaaactt aatccgctga tcggtagaat caataaaaaa
    12601 taagcaagga aaaacaaaaa agtaatgggt ctcactttct tcagctgaag tatcgtcaag
    12661 tgtaagagtt gcttcaaaga gattggttct ttctttttaa taaaaaaaac actcatcaaa
    12721 agaaaagtaa attcgaaata aactaacagt aaaatcgtca tcaaaactac gattaacgag
    12781 agtagaaccc caggatgttg agaaaaaatt gaaggaatat tgtcataaga caaatagtca
    12841 attgcccctc ggtgtaaaat aaaacgggtc gtactgctca ataagggtaa acaaataaat
    12901 aaaataaagc catgcatcag caagacatca cggaaataag cttgtgttcc ttttaaaaag
    12961 tcccaagcat tacctaagct acgtttcaaa taattcatcc tatcacctgc tcttcacatt
    13021 gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt tttgcagacc ctttcccaga
    13081 tttaac
//
LOCUS       DAZAOD010000073        12928 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000073 DAZAOD010000000
VERSION     DAZAOD010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.075"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(55..1560)
                     /locus_tag="ACHDPO_002060"
     CDS             complement(55..1560)
                     /locus_tag="ACHDPO_002060"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFN3369675.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(1652..2242)
                     /locus_tag="ACHDPO_002061"
     CDS             complement(1652..2242)
                     /locus_tag="ACHDPO_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFN3369676.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            2421..4067
                     /locus_tag="ACHDPO_002062"
     CDS             2421..4067
                     /locus_tag="ACHDPO_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFN3369677.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            4116..4835
                     /locus_tag="ACHDPO_002063"
     CDS             4116..4835
                     /locus_tag="ACHDPO_002063"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFN3369678.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            5314..6261
                     /locus_tag="ACHDPO_002064"
     CDS             5314..6261
                     /locus_tag="ACHDPO_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369679.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            6273..7193
                     /locus_tag="ACHDPO_002065"
     CDS             6273..7193
                     /locus_tag="ACHDPO_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369680.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            7234..8691
                     /locus_tag="ACHDPO_002066"
     CDS             7234..8691
                     /locus_tag="ACHDPO_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369681.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            9036..9650
                     /locus_tag="ACHDPO_002067"
     CDS             9036..9650
                     /locus_tag="ACHDPO_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFN3369682.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            9643..11367
                     /locus_tag="ACHDPO_002068"
     CDS             9643..11367
                     /locus_tag="ACHDPO_002068"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFN3369683.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            11364..12815
                     /locus_tag="ACHDPO_002069"
     CDS             11364..12815
                     /locus_tag="ACHDPO_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFN3369684.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
BASE COUNT         4192 a         2237 c         2591 g         3908 t
ORIGIN      
        1 aatcacagtc cctttttttc ttagaaatgg gaaaccacta gtatataaat accattattc
       61 ttcaatcaac cgcttcacga ttgcataatc cccttcataa ggttcatcta caccattgat
      121 tttttgatag ggatccacgc cttttcccgc aataacgact gaatcttgcg gagcgctttc
      181 tgctaaagcg cgtcgaatcg cttcaggacg atccatttca taatgaacga tcaaatctgg
      241 attagtaatt gcttcattga tttcttccgc gatttttttc ggatcttcaa atgctgggtc
      301 atctgccgtc aaaaaggcga tgtcagctgt ttctgatagc acttttccaa aatcatgtcg
      361 acgggagatt gctttgtttc ctgggctgcc taatacaaca attacacggc catctggatg
      421 ttcatttttg gcaaattcca gcaatgtttt caagcttaga taattatgtg catagtccac
      481 atagacatgc gctccattgg attggatcaa ttgatccatt cggcctggta cacgagcttc
      541 ttttaatccg tcttgtgcat cttgactgga ggcacctgtt agtgctgcgg caatgatcgc
      601 actggctgca ttttcttggt tgaatcctcc agccagcaaa atatcataag cagtatcgca
      661 gatagctaag cgatcttcat gagaagataa agtaaaaccg tgagtacctt tatctgaacg
      721 gatcacttga taattgcttt cttccgaacg accataagtg atcgttggaa tctggaatag
      781 atcggctgtt tccctaagta aatcaaaata gtcactttca tgatttaaaa caactgtttt
      841 tgaattcaag atcaattgtc gcttgcaata gaaatagtca tcaaatgtcg gatgttcgat
      901 cggactgata tggtcaggcg agatattcaa gaagattccg acatctaaag tcaagccgta
      961 tacgcgttgt gttttgtaag cttgtgaaga aacttccatc actagatgag tcataccatt
     1021 ttcaactgct tctgacatca tacgatataa atctaatgac tcaggcgttg tcaaatggga
     1081 tttgaaatat gttttgccat ctaacgttgt attcatagta gaaagcaatg ctgttttttt
     1141 atttgttgtg tgatccaaga ttgcttttgt aaagtacgca gcagttgttt taccttttgt
     1201 tccagtgaat ccgatcactt tcaatttatt ttgcggatag tcgtaaaaag ccatagcaag
     1261 aagcgccatt gctttacgga tatccgttac gatgattcct actgctgaat tttcgtatgg
     1321 ttgttctgat acataatatt gaataccctg ttcgattgct gaatccaaat attcttcttt
     1381 gaaattcatt cctttacaga aaaacaaagt agaagcatca gcttttcttg aatcataact
     1441 taactgaaga aattcagctt tttctggtac atcaagatgc cagcctcttg ttgaaacaaa
     1501 ttcttttaat agattttctt ttaatagtaa atgacggatg tcttctaaag agaagctcat
     1561 tgattgatcc ctcgctttat tcaatttctt ggtttattat agcacactct ttttaatata
     1621 tcgtttgttt ccgctatgac aaaatccagc tttattcaaa ttttcttgac acaggggaca
     1681 agcggatgag tattttcata aacaatgaac tgactgtaat agataggaga acgaatagtg
     1741 tctccaacaa tccaaaaaca taataattca aaaagacgat aagactattg gtaagtaaaa
     1801 gtccttgcgg cattggaagc cgaaaaaatt tgtggaaaat aatcggcggt atcgttatac
     1861 cgccatttga ggccccgact gtgtacaatg tgtaaacccc aagactgaac aaaagacttc
     1921 ctgaaatcag tgaaaagaaa tgtgaggaga tcatttccac ttttggaaca atctctaaaa
     1981 caacaggaaa aagcagactt cccgctacag tcttaaaaaa tactgatttt cctaatagga
     2041 cagcggctag aagcagcatc ataagattga tgctccaaac agtaactgag cgttggatag
     2101 aaaaggccgt ttcaactaaa tgtccgatgg cgcccactcc ggcggaagct atatcgtgag
     2161 ggagcaagaa ccaattcaat ccaactgtga taaagaaaag acctaaaaat ataacgggta
     2221 gtttttttat ttcttgtgtc attgatatct cctataaatg ttagccataa aaggctgtat
     2281 atttctttac tttaccaaaa aaacgaaacc gaattcaaaa aaacaattgt tcttataaaa
     2341 gttatataaa atcgattgcc agtttctgtt ttaccaatta aaatgatagt aatgttttgt
     2401 agaaagttgg aatctgaccg atggataatc aaagaaaacc agcattagat caattaacac
     2461 cgcaagaaaa aatggcacga ggctctgctt ggatgaccgc cagtaatatc atttcaagat
     2521 tgctaggcgc tgtctatatc attccctggt atgcttggat gggcgaaaat gctaaggctg
     2581 ccaatggatt attcaatatg ggatacaata tatatgcatt gtttctactg atctctacag
     2641 caggaatacc tgctgcgatt gcaaaacaaa ctgcacgcta taattcattg aatgaatatg
     2701 gcacttcacg acgattattt atccgtgcat tacagatgat gggcgggcta ggcctgttgt
     2761 ttgctttgtt catgtacatc gcctctcctt ggctagctca tgcttctggt ggcggagaag
     2821 aactgattcc aacgatgcgt tctttgagta tcgctgtatt ggtttttcct tgtatgagtg
     2881 tgatacgagg gtattttcaa ggcaatcaag aaatgatgcc ttatgcgctg tcgcagattg
     2941 tagaacaggt ggcacgtatt ttttatatgc tattggctac attcatcatc atgaaagtca
     3001 tggatggtga ctatgtgacg gcggtcacgc aatcaacttt cgcggcattt atcggtatgc
     3061 tagcaagtat tcttgtcctt ttgtattttt tgaagaaaca tcaagcgtat acatcggcgt
     3121 ttattcacta cagcgaaaac aaaataaata ttgcaacgaa ggaattgttg ttagataccg
     3181 ttaaagaagc gattccgttt attattgtgg gttcaggggt aacgatcttc aaattagtcg
     3241 atcagttcac ttttatgaag atcatgtctg catccaccga gtattccaat gcacagttac
     3301 tggatctttt ttcgattttt agtgccaatc cagataagtt gacgatggta gttattgcat
     3361 tggcaacatc gatcgcgtct actgggttac cgttgattac agaagctgtt acgttgaaag
     3421 atcgagtagg tctggcaaaa ttgacaagcg gaaatttaca gttgttttca ttttttatgt
     3481 ttccggcgac atttggtgtt atgttacttg cctatccgct aaatacatta ttttatacac
     3541 cggattctct aggaagtaat gtactgatcc aagcaagttt tgtaggactc ttcctaggac
     3601 tatatatgct agtttccaac atgctgcaag gaatgtttga aaacaaggcg gcaattaatt
     3661 atttggttat tgggtttcta gtgaaactcc ttcttcaata cccagccatt cgtttatttg
     3721 aagtatacgg ccctttattg gcgacaatga tcggatttgc tgtgtcttgt accttgatct
     3781 taaagagaat ccatgaagta gcccgcttta aaccaagttt tgtctggcgc aggacattgc
     3841 tgatctttat tcttaccttg attatgcttt tggcttcgtg gatcacaaag atgatttttg
     3901 gtgctttttt aaacgaagat agcaaattcc agtctctatt gttgattctt gtagtagcag
     3961 gtataggggc tttagtgtat ggttatttag ctttgaaaat ccgcttggca gaaagactac
     4021 taggaccagg aatagcgcgt ttacgacata aattaaaaat aaaataagtg aatcagaaga
     4081 gctagattga tgctcttttg aaatggggga aacgcatgcg tttagataag tttttagcag
     4141 atatgggact tggcagccgc aaagaagtca aaggattgat caaaaaagga acgatcgaag
     4201 tcaatggaca agtggtgaaa agcgataaag cgcaagtaaa tgaattcgaa gatgcggtta
     4261 cttatttagg agaaatcatt acgtatcaaa aagattttta ctacattttg cataaacctg
     4321 caggagtcat ttctgctact caggataatc atgatcaaac cgtaatcgat ttattggaag
     4381 accaggatta tcgggaagat ctttttccag tcggccgatt agataaagac acagagggcc
     4441 tcttgatttt aacgaatgac ggggtgtttg cccatcagtt actatcacct aaaaaacatg
     4501 tggagaaaga atatctagct gaggttagcg gtataatgac agaagaagat atccgtttat
     4561 ttgcagaagg actgattatt gatggcgatg agcagacatt gccggcaaaa ctccaaattg
     4621 atcaagtaga tcaagagaca gaaacttcaa ttatccgtct gattttgcat gaaggaaagt
     4681 ttcaccaagt taagcgaatg gtcaaagcag taggaaaaga agtcttatat ttaaaaagaa
     4741 tccgtatggg aaaattttgg ctgcctaaag atttgaataa agggcaatat cgacccatga
     4801 ccaaagaaga gctagaacaa gtgagagaaa aataattgaa tggatagcta aaagaataag
     4861 cagagtagtt gtagcgccat ctgaaaagca gacttgtccg tctgactttc ggatggcttt
     4921 tttgtgaaat ttcggcttat ttccgtagaa gctacttctg gaacaccgtt tgttcggaat
     4981 aagggactgt gacaagactt ttgttacagt ccccattgtt ccttgtgact cagagttaga
     5041 tagtaaggac acgatctccc taatactcag gccaaaacgc tgaattcaca acctctgata
     5101 aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa tatgaggaac
     5161 tattttcccg tttttttctc taatactcag gccaaaacgc tgatttcaca acctctccta
     5221 tactttgttt cattttccct atactttgtt tatttattct cattattgaa agcgctataa
     5281 ttacgttgcg aatgaatcga aaggggtttt tagatgaaaa aacgaaaggg gttcaatcat
     5341 ttttttatga atctatggcg ttataaagca cttgtcctga tggctgtacc gggtatgctt
     5401 tggatgattt ttttctttta catacctgta atggcgaatg tcgtagcatt caaaaatttt
     5461 catatttcag cagatgggtt cttggctagc ttgagggaaa gtccttgggt gggttgggaa
     5521 aatttcaaat ttttattttc ttcggatcaa gcatttctca tcactaaaaa tacaatttta
     5581 tataatgtag catttatcct tttgaatctg ctgatctcag tcgtatttgc aatcattatg
     5641 agcgagttga gaaataaacg actcgttaaa gtttatcaaa cgatgtcctt actaccttat
     5701 tttctatctt gggtcattat cagttacttt gtttacgctt ttttaagtcc tgacaaagga
     5761 atattcaatc agtggatcac tggacatgga ggagaagctg tcaattggta taatgaaccg
     5821 aaatattggc cgtttatctt ggtgttcatt ggtacatgga aagggattgg ttataacagc
     5881 attatttact ttgcatctgt tatgggaatc gatccgactt attatgaagc tgctatggtt
     5941 gatggagcta gcaaatggca gcagatcaaa catgtgacga taccacaact tattccacta
     6001 atgacgattt taacgatttt agccgtagga aacattttcc gagctgattt tggcctgttt
     6061 tataacattc ctaggaattc cggtgcatta tatgatgtga ctcaagtttt ggatacgtat
     6121 atctacaatg gcctgacatc cacaggagat tttggtatga cggctgctgc aggactttac
     6181 caatcagttg tcggctttgt cttgttgatg atcacaaata cgatcgcccg acgttttgat
     6241 agcgattctg cattattcta aggaggaaaa aaatgaaaaa aaagaaagtg gagagagtcc
     6301 aagtccgctc tttcaataag acggctaatt ttttctctaa tataatgatt gcactctttg
     6361 ctatttcctg tattttgcca tttatatttg ttatcgccat ctcttttacc gatgagtcca
     6421 tattgtcgac tcacgggtac agtttttggc cagaaaagtt cagtatattt ggttatacgt
     6481 acttgttcga ccagatgcag gataaaattt tccaagcgct tttcgtcact gtacttgtta
     6541 ctgttttagg tacactgatc aatagcacgg ctacttcttt atatgcttat gcgatttcac
     6601 ggtcaaactt tccattccgt cgttttttta ccgttttttg tttaattacg atgttgttct
     6661 caccagggat ggtggccaat tatcttgtta tgacaaatct tcttcagtta aaagatacga
     6721 tttgggcatt gatcttgcca atggctgtca gtcccttcaa tattattgtg atgcgcacat
     6781 tctttaaacg ttcggtctct gattcgatta ttgaatcggc acggatcgat ggagctagcg
     6841 aactgcgaat atttgttcag atcgttttac cgttagctgt tccaggtatt gcgacaatca
     6901 gtttatttgc cgcattgggt tactggaatg actggttcaa tgctttacta tacatccaag
     6961 atgataagct agttccacta cagtatcttt tgatgaaaat ccaaagtaat attcaatatc
     7021 tgacacaaaa ttcaggagca ggaagccaat tgacaggcgg attagcctca gttccaggag
     7081 aatctgccag aatggcgatc gtagtcatct cgacgttgcc tattgcgatc agctatccat
     7141 ttttccagaa gcattttgtc aaaggtctaa caatcggcgg agtaaaagaa taaagaaaca
     7201 aaaatataaa tcataaaatt aggaggaaga aaaatgaagt tatggaagaa actagccttt
     7261 acaggtgttt cagcgttgtt gttgggaaca ttagcagcat gcggaggttc tggttctaaa
     7321 gaccaggcag aagctagcaa ttcggacact ttgcagatgt atcaaatcgg agataaacca
     7381 gataatttcg atcaattgat ggaagtagca aacaaacgaa tcgaaaaaga gatcggtgta
     7441 aaagtcaata tcaattacat tggctggggc gattacgaaa agaaaatgaa cgtcatcatt
     7501 tcttccgggg aaaattatga tatcgccttt gcgaacaact atgtttccaa tgcccaaaaa
     7561 ggagcctttg ctgatttgac tgaattagcg cctaagtacg ctgaaaaagc ttataatgat
     7621 ttagatgaag catatattaa aggaaatctg gtcaatggaa aattatatgc tttcccagtc
     7681 aatggaaatg tctttgctca acaagtactt acttttaaca aagctttact agataaatac
     7741 gatctttcaa ttgatggaat ccaatcttac gctgatgcag aaaaagtctt gaaggaattc
     7801 catgaaaaag aaccaaacac ggcagctttt gccattggac aaggcttcaa agtccaaggg
     7861 aactttgatt atcctttagg gaatacgtta ccatttgcta ttgatctgga tggagatgat
     7921 tcgaaaatca tcaaccaata cgataatgaa acgtatatcg gactgttacg tacaatgcat
     7981 agctggtaca aacaaggact cattccaagt gacgctgcaa cgagcaataa ggattatcca
     8041 ctagaaggaa atacttggct aatgcgtgga gaaacacaag gaccgtatga ttatggcgat
     8101 acaattttga caaatgcagc aaaacaagaa cttgtctcaa aagcaattac tgttccacta
     8161 aaatctacag ctcaagcaca aatggcaaat tttgtcgtat caaatacttc aaaaaataaa
     8221 gaaaaatcag tagaacttct agggctgctt aacagtgatc cagaattatt gaatgggctt
     8281 gtttggggga tcgagggaga agcatgggaa aaagtcgatg gttcagatga taaaatcaaa
     8341 ttgctagatg gttatcagcc aaatacacat atgtctgctt ggaatacagg aaacaacaag
     8401 attctatata cacaagagtc tattacggat gacatgattg ccaaacgtga tcaatcgatt
     8461 gctgatgcag aaacttcacc gattttagga ttcagcttca acactgacag tgtcaaaaca
     8521 gaattaagta atatttctaa tgtcatgaat caatatttag atggattgaa tacagggact
     8581 gttgatccag atgaaacatt accgaaattg aaagacgctt tggacaaggc tggctatgat
     8641 aaggtattga aagaaatgca aaaacaatat gatgagttcc gacaagaata ataatgaata
     8701 aagacaaagg ggttgtgaca aaagacgtgt cacaacctct tgttccgaat aaacggtgtt
     8761 caaaagccag tttctcggta ttaagctaaa tatatgtaaa aatgtggaaa gccatattca
     8821 caaaattttt cttactactc gaaactaagc ggctatttca caaactcttg gtaaacggtg
     8881 ttcaatcagc taaccctcgg tattcgctca caaaacgaca aaatatgagg aactattttt
     8941 ccgtttgttt ctctaataat caggtcaagg tgctgattgc ccaacctttt tttgtataat
     9001 gagaaagtat aaacttaatg tttggaggag aagatatgtt agggaaggtt ttggaagagt
     9061 tatttatccg gatctgggtc attataaaac taaccttgta tttctggata tatacatttg
     9121 ccggcgggat catctttgga ttaggtgcgg catggaaaac agtcaatgaa ctattttatt
     9181 tgtacggatt cgagtataaa gaaatcacaa taaaaagagg ctggaatata tataaaagaa
     9241 attttttaag aggcaatctg ctatttagtt tatttttatc tggtactgct ttattgagtt
     9301 acaatttata tttatctgtt caaatcaaag ggctcatttt tttagctatt gattttattt
     9361 tactttttgc cttgctctgc ctatttgcta cttatcaata cagtatgatt ttagatagtg
     9421 aatatacgat ctctgttcct aatctgctaa agctaagttt tatttcggtt ttttccagct
     9481 tttcgtcttt tctaaaaata attattggta gcggtataat tttaggcgtg acttggcaat
     9541 tcaaaggatt gatcctgttt ggtgtcattg gtcttttgac ggtttggaat ggtacgatga
     9601 caacacattg gcgtgaagaa ttagataaac agttggaaag ttatgaataa gtttcggatt
     9661 ctattttcaa aaggaacctt actaaatcgt ctgttgcgga aatacgcggt tatcatgatc
     9721 ggtgtaacga tgactgctac cgttattttt agtatccata cttgggaaca aaatcaaaaa
     9781 caggcagaaa acatgacaag tgatgccgtt caaagcacaa gcagaatgct gaatgataaa
     9841 acaaccttga gtaggatcat caaaaaccag cttgtaggga attccgaaaa gatcgaaaat
     9901 gtgacgacct acttaacaaa acccatagat cagtatctga tgtatgtata cgaacagcaa
     9961 aacagtaccg atgaattagt ttctttccca aatcaaatca aagatctcta cgcaaattat
    10021 gaagaactaa gtgcgatata tatcgtgttg aatcaactac cggagtatta tgaatcttct
    10081 agagaaaaca aaggtgggga aataaaaaag gggacaccaa aattactaga cgccttttat
    10141 atcaagttgc ctatcacaca aggaggagct gagtcaggaa gtatttttat tggttttcaa
    10201 aagaaagaac tagatatgat tttagaaaat ctaacgtcat tcaatggact ctctttatac
    10261 atgatttctg gaacgacaaa tcgactatac acattccatg ataataaaat agctaaagaa
    10321 acgtttgaaa gacaagaaat gatcatcaca gagagtctga agaaaaattc acaattgccg
    10381 attgacgatc tggaaaaaaa caattttgtt caacaccaag aactgtctga tgattatcgt
    10441 atattagctg tactagataa aaaaagtgta aaaatcgaaa cgggaaaaaa tcttgccccg
    10501 ctgatcattg gtatcattat tttagacaat atactgctta tctttcttta taaaacattc
    10561 aaacgatatt cacagcaagt atctatcgtc atgcaggcca tggatcaaac agcagcaggg
    10621 aatttagaga cgcggatcga cataacaaac acggaatatg aactgaagga actttcaatc
    10681 ggtatcaacg aaatgttgga tagcatcaat cagtttgtag aagacatcta caaattagaa
    10741 atcaaacagc aagacgcaca tatgcgggcg cttcaagcac agatcaatcc acacttttta
    10801 tataatacat tagaatatat ccgaatgtat gcaatcagcg aaggaagtga agaattagca
    10861 gatgttgtgt atgcgttttc cgctttgctt cgaaacaata cgaatcaaga gaaaacgatc
    10921 actttaaaag aagaactgga cttttgcgaa aaatatgtct atttgtatca aatgcgttat
    10981 cctaatcgag tagcctatca ttttatgatc gatcctgatt tggaaaagat cgaagtacct
    11041 aaatttgtga tccagccatt agttgaaaat tattttaaac acggtattga ttttactcga
    11101 ttcgataatg cgctaagtgt caaagtcttg caggaaggca aacgggtaag gatcatcatc
    11161 aaagataatg gaaaagggat gactgaaaaa cggctaaaac agattgaaga aaaactgtct
    11221 catcctaaag tggaacttca cggttctatc ggtctgcaaa acgtgaatga acgtttacgt
    11281 gccagcttcg gcagcagtta ttatatgtcg cttgagaata atgagacagg tggactgacc
    11341 gtttctatta cattcaagga gggatgagcg tgtatcaagt gttattggta gatgatgaat
    11401 acatgatttt gaatgggtta aaaaagataa ttgattggca aagtttaggc tttcaaatag
    11461 tagcaacagc agagaatgcc aaagaaggac tagctgtact tgaacagcga cagattgatt
    11521 tagtagtaac ggatgtgaca atgccagaaa taaatggact ggaatttatt gaagcggctc
    11581 aaaaagaacg tcataatttt gaatttatga ttttatcagg ataccaagaa ttcgattatt
    11641 tgaaaggagg tatgcaatta ggcgccgtga attatttgat gaaacccgtg aataagttcg
    11701 aattggttga aagcctcaag aaaatcaaaa cacggttaga tcagcaaaat gaacaaaaaa
    11761 atcaacaaga aatctatcaa gaactgttat tcagtcaatg gttgaatgaa gaattggatg
    11821 aaataagtga agaagaaata ataggacaaa taagtgagaa gcagcatagg atagtattga
    11881 ttcaactggc aagaactcat gatactctta tcaatagatg gttgcaagaa cggcaacaaa
    11941 tcttttacta tcaacgaaat tacggagacc gtgtattgat cacgttgttg ttggaggcag
    12001 atgaagttga tggcttctgt tgttttgttc aagaaaactt tcctgatcag gaatggctga
    12061 tcagtatcgg ggaagagaca gattctttgg acaaaatccc tgaaacattc caacaagcga
    12121 aagacaatct acagttgcat caattttatg gagataaaga cgagcatgtt ttttacgcag
    12181 tacaagcaga aacaaaagat caaaccatcg atttttcaag tttcagacgc gtgctgcaaa
    12241 ataaacaatt ggaagtcgct caaaaaatga tcactgattt ttttgaacag tttcagttag
    12301 cagccatgat gccggaagat atacgatatt ccagtttttt actgtttatg gagattcaac
    12361 gggaattgat tgatctggaa gatgaggaat atttacaagg aatcgaaaaa atccatcagg
    12421 caaaaacggt gcaagaactt cagcagctac ttctgtcatt catcaaaaag catcagagac
    12481 agaaaaagta cagtgacaat gtggaaaaag taatcgtaat cctgcaccag cattatcaag
    12541 aaccacttac actcaaagaa gtgtcagaaa acctgcattt aaatgtcatg tatctaggac
    12601 agctgttcaa aaaagaaacg aaaaaaagtt tttcagctta tttgaaccat ttacgtatgg
    12661 aaaaagcgaa acaactgctt ttgcacagta atcaaaacat caatgagata gcaagtgaga
    12721 ttggctacaa caacaccacg tatttctcta aattattcaa gaaaatcgtc ggcagatccc
    12781 ctaaagagta ccgagaaaac agtggagaat cataaaaaaa aaagccaatg taatgaaata
    12841 acttataaaa aattgtctag aaatctaatt ttgggctgtt cttattactt gaggcaaggc
    12901 agctttttca tgacctctcg ataaacgg
//
LOCUS       DAZAOD010000074        12737 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000074 DAZAOD010000000
VERSION     DAZAOD010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.076"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACHDPO_002070"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACHDPO_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFN3369685.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="ACHDPO_002071"
     CDS             complement(323..892)
                     /locus_tag="ACHDPO_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFN3369686.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="ACHDPO_002072"
     CDS             1078..1980
                     /locus_tag="ACHDPO_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFN3369687.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACHDPO_002073"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACHDPO_002073"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFN3369688.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACHDPO_002074"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACHDPO_002074"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFN3369689.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="ACHDPO_002075"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="ACHDPO_002075"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFN3369690.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="ACHDPO_002076"
     CDS             8548..8733
                     /locus_tag="ACHDPO_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFN3369691.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="ACHDPO_002077"
     CDS             complement(8795..9991)
                     /locus_tag="ACHDPO_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFN3369692.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="ACHDPO_002078"
     CDS             complement(10161..11597)
                     /locus_tag="ACHDPO_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFN3369693.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="ACHDPO_002079"
     CDS             11890..12699
                     /locus_tag="ACHDPO_002079"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFN3369694.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4011 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaat
//
LOCUS       DAZAOD010000075        12555 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000075 DAZAOD010000000
VERSION     DAZAOD010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.077"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(121..483)
                     /locus_tag="ACHDPO_002080"
     CDS             complement(121..483)
                     /locus_tag="ACHDPO_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369695.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(557..937)
                     /locus_tag="ACHDPO_002081"
     CDS             complement(557..937)
                     /locus_tag="ACHDPO_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFN3369696.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1019..2194
                     /locus_tag="ACHDPO_002082"
     CDS             1019..2194
                     /locus_tag="ACHDPO_002082"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFN3369697.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2271..2855)
                     /locus_tag="ACHDPO_002083"
     CDS             complement(2271..2855)
                     /locus_tag="ACHDPO_002083"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFN3369698.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3056..4054
                     /locus_tag="ACHDPO_002084"
     CDS             3056..4054
                     /locus_tag="ACHDPO_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFN3369699.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4166..4675
                     /locus_tag="ACHDPO_002085"
     CDS             4166..4675
                     /locus_tag="ACHDPO_002085"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFN3369700.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4705..5364)
                     /locus_tag="ACHDPO_002086"
     CDS             complement(4705..5364)
                     /locus_tag="ACHDPO_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFN3369701.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5366..6130)
                     /locus_tag="ACHDPO_002087"
     CDS             complement(5366..6130)
                     /locus_tag="ACHDPO_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFN3369702.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6138..6815)
                     /locus_tag="ACHDPO_002088"
     CDS             complement(6138..6815)
                     /locus_tag="ACHDPO_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFN3369703.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(6852..8237)
                     /locus_tag="ACHDPO_002089"
     CDS             complement(6852..8237)
                     /locus_tag="ACHDPO_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFN3369704.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8447..8531)
                     /gene="ffs"
                     /locus_tag="ACHDPO_002090"
     ncRNA           complement(8447..8531)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACHDPO_002090"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8554..9069)
                     /gene="tadA"
                     /locus_tag="ACHDPO_002091"
     CDS             complement(8554..9069)
                     /gene="tadA"
                     /locus_tag="ACHDPO_002091"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFN3369705.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9175..10032
                     /locus_tag="ACHDPO_002092"
     CDS             9175..10032
                     /locus_tag="ACHDPO_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3369706.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10113..10448)
                     /locus_tag="ACHDPO_002093"
     CDS             complement(10113..10448)
                     /locus_tag="ACHDPO_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369707.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10515..11885)
                     /locus_tag="ACHDPO_002094"
     CDS             complement(10515..11885)
                     /locus_tag="ACHDPO_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFN3369708.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(11963..12499)
                     /locus_tag="ACHDPO_002095"
     CDS             complement(11963..12499)
                     /locus_tag="ACHDPO_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3369709.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         3736 a         2557 c         2102 g         4160 t
ORIGIN      
        1 gaaaataaaa tgcactaaaa aactatcttt agcagaacat ttcattgtat tttttggacc
       61 aaacaataaa aaaagaagtt tgaaaaaaat tcaaacttct ttgttcgctt aatctgtatt
      121 ttagaagaaa ggcactccct ctacttcgta agttccaaga acagagcgca tttgacctgg
      181 ttcttcccaa atatatcctt cgcctaattc ttctctttga ttcttttgtt cagtttcaaa
      241 gacaaacaac ggaacatttt cctctttaat atgtgtattt gtcaattcca tcaaactaat
      301 cttgctaaca tcgatatgaa ctatttcttt taagaaatta agtatattcg ctaaaccagt
      361 ctttccttca gaaagttccg ctaacgcaaa ttccaacttg tcatcaattg aatggaccaa
      421 aaatttttta gtaccatcct ccaaatgcaa cataattgta ccagcaactc ttttgcttgc
      481 caaaatttcc acctcgatca acttgttcta tggcttacat aaaaattcta gcacattttc
      541 agaaaaaata cactttttat ttcttatttt ctttccgttc tagttcagat aatgcttctt
      601 ctatccaaat aggtaactgc tccgcaatag tggtaaatcc gatcttacga tttttattcg
      661 tgaaatacct ttttctgcga tatggaacag ctggatttgt tttttctaac gttcttaaag
      721 ataaactgat ttttttggaa tattcatcaa tgtcgatgat ctgaactgtt actggctgtc
      781 cgacttttaa caatgaatgg atatttttcg tataaccgga ttgtacttct gaaacatgaa
      841 taagtccttg cgtctcgtta tcaagagaaa cgaatgcgcc ataaggctgt atccctgtca
      901 cttttccttc aattatttgt ccaattttat aagtcatcta cttccctctc ttcgcattta
      961 tcattatact gtaaatagct caaaaaaaga agcgacgaaa atgactggag gtcttaagat
     1021 gatcgaattt gataaacaga tttcaagaaa agatacagaa agtgtaaaat gggacgcaat
     1081 tgctgagaca tatcaaatgg atgacttact tcctttgtgg gtagcagata tggacttctt
     1141 gtctcccggt ggggtagcta aagcgtttag tgaatacatc aaacatggaa tctttggtta
     1201 tgccactctg tctgataaac tatatcaggc tatcattcat tgggaacgcc aacaccatgc
     1261 tgtggagttg acgaaagaaa atatcgtttt tacaagtggt gtgttaacca gtttagctgc
     1321 agcagtacaa acttttacaa aaccaggcga ttctattttg attcatgacc cagtttatcc
     1381 tccattttcc tctattatag aaacaaatca acgtcacatc gttcgaagct ctttgctaga
     1441 aaaaaataat catttcatca tggacttgtc tgacatggag aaaaaaatcg aagaaaacaa
     1501 tgtaaaagca atgattttat gcaatcctca caatcctgga gggcgtgttt ggagcaaaga
     1561 agaattgaaa cagttaagcg aattgtgttt aaaacatcaa gtgattctgt ttagtgacga
     1621 gatccatcaa gatttaactt tattcgatca tacatttact tccatgctaa cgattgatcc
     1681 taatttagat gatctactag ttgcttttac ttccgcaacc aagactttca atctagctgc
     1741 aatcaaaaat tcaatggtat ttatcaaaaa tccagagatg aaagctgatt ttgaaaaaca
     1801 tttagtgatg aaccaacagc acgaaatcaa cacttttgga ctgattggaa cccaagcggc
     1861 ttatgagacg ggtggagaat ggttaagcca actgattcct tatctagaaa aaaatgttca
     1921 aacagttaat cagttttttg aacagtatct tccgaaagtg agaataatga accctgaagg
     1981 aacttactta atgtggttag attttaccgc ctatatttca gacgaccaag aattggagaa
     2041 cactcttgtt cggaaaggaa aagtcgtatt aaatcctggc atcacgtttg gtccttccgg
     2101 tcatgggcat atgcgcttga atattgcttg tccagaagaa actttactgg aaggacttaa
     2161 tcgaatcaag tatgctttag agacaatcga ttaaatcatt tattcaaaat aaaaggacga
     2221 gaccttacta ggtttcgtcc tttttcataa ttactccgta ccataccaaa ctattctgaa
     2281 atttcaattg tttcaatcac tacatcatgt acaggtcggt cttgtggacc acgttgtaca
     2341 tttgcgattt catctactgt gtccatccct tctagtacat gtccaaagac tgtatgtcgg
     2401 aaatctagcc aaggagttcc gccaccttta tacgcttcaa tgatttctga tgggaatcca
     2461 gcaccttcta gttgtccaag catattagct ggcacatttg tgttatttac aataaagaat
     2521 tggcttccgt ttgtgtttgg acctgaattt gccatagata aagctccgcg aaggttgaac
     2581 agttcacgac tgaattcatc ttcaaaactt tcgccataaa tactttcgcc acccattcct
     2641 gttccagttg gatcgccgcc ttggatcatg aaatcaggaa taacgcggtg aaaaatcacg
     2701 ccatcataat aacctttttt ggaaagttca atgaaatttt gaaccgtctt cggtgctagt
     2761 tcagggaata attgaacagt aatgtcacca cggtttgttt tgataacagc ttttggtcct
     2821 ttttcacttt ttaaatctag ttgtgggaat gccatattgt ttcctcctaa tatttgcata
     2881 cttcataata ataataacat aatacctaac ctctcgtaaa aatactagat ttgttttctt
     2941 ttatttttca tcactagata cattctataa cttaccgttt cgatttcgaa ttcaaacatt
     3001 tttgagaagc attctcaatt aaattctgat atagtgtgaa aagggaggaa tttttatgga
     3061 aatctatgac attacaatca tcggtgcagg tcctgtaggg atgtttgccg ctttttacgc
     3121 aggaatgcgc caagctaaaa caaaaatcat tgacagtcta cctcaacttg gtggtcaatt
     3181 agcaactttg tatcccgaaa aatatattta cgatattcct gggtatccag caataaaagc
     3241 aagtgaatta atcgatcaat tagaaaaaca attaactact tttaaccata cattccattt
     3301 aaaagaagaa gttctctcgc ttactcgtga agacgaagtt atcgagatta ctacaaataa
     3361 aggcatccat tattccaaag cagtcatttt agctttagga aatggttcat tccagccaag
     3421 aaaattgaat ttagataatg ctgaatcatt tgaaaaccac ggattggatt atttcgtgaa
     3481 tgatttgatg aagtatgctg gaaaaaaagt cgctattgct ggaggtggtg attctgctat
     3541 cgattggacg ttgatgttag agcctattgc aagcgaagtt tacttgattc atcgtcgccc
     3601 ggaatttcgt gcgcacgaac atagtgtatc acgcttgaaa tcttcatctg tcaacttgct
     3661 tactccctat ctcatcgatg gattatcagg caataatggg gaactgacag atatccggtt
     3721 aaaaaaagtg aaaagtgacg agacgattga tttgatgatt gattctctga tcgtcaatta
     3781 tggattctct tctaatttag aacatctttc ttcttgggga cttgatagta ccagaaatgc
     3841 cattactgta aaatcagata tgtctacttc tattccaggc gtttatgcag ctggtgacat
     3901 ctgtacctat gaaggaaaag tgaaactgat tgctactggg ctcggtgaag cacctactgc
     3961 agtgaacaac gctttacact atattaatcc aaaggaacga actcagcctg gtcacagcac
     4021 aagcttatac gataaaaatc ttcgtcctag ttgatttttt atatctcttt gcatttcaag
     4081 ttaaacccga aagcagtttc ttgcattttt ttcatgttcc gttaacatga aatagagaaa
     4141 gaaaaaataa agggggagca ataatatggt cgtcaaaact gagactttag aagaaaaggc
     4201 aagagaacta ttgaaggaac gtggcgtaac tgtagaagat atcgcacaac ttgtcatgtt
     4261 tttacaaaaa gactatattt ctgatttgac tttggcggat tgtactgaaa gtgtcaacag
     4321 cgtgctaaca aagcgtgaag tacataacgc cattatcact ggaatccaat tagatatatt
     4381 agcagaaaag aaaaaattga tgagtccgtt gcaacatatt atcgaagatg acgaaggcct
     4441 ttacggtatc gatgagatcc tagccttgtc aatcgtgaat gtttacggta cgatcggctt
     4501 tacgaattat ggttatatcg acaaggtgaa acctggtatt ttaaaagaac taaacagcca
     4561 cgatggcgtt catgtccata ccttcttaga tgatatcgtc ggagcgatcg ccgctgctgc
     4621 tgccagtcga ttagcacaca aagaaccaga aaaaagaagt cgccttactc aataattcaa
     4681 caaaaaaaga aagaaaacgt ctatttagac gagttctttc ttttttgttt gtttcaagct
     4741 attttttcct aagaaaagaa aaacagcaaa aaataattct aataatacaa aaaataagat
     4801 aaagctatgc atgaaaaatt cttctggaag tacattgatg attggatcag taacgggatc
     4861 gaataaccag tcatcgttgt tgaaaaacgt ttcatgaaaa aggataaaaa agcgatcaaa
     4921 tcctatcatc atgaaaaaac cgaaaacaac tggcagtaac atgccgattt gaaacggacg
     4981 aatcaaccgc caaagccgat cattcttttg caaatatttg ataaacaaaa tactcgggat
     5041 caaagtgatg aaaaacacag cataatccac taaaaacaaa attttcactt cataaaagtg
     5101 atgggctccg ctagcagaaa ctgggaaatc tggcaagctg aggatggttt tgaagggatt
     5161 attgagataa ttcattaggt gatcaaaatt tttcagtaac gtctcttgat ctaaagaagt
     5221 ataatccaaa atttgcaaat gtccgatatc aaatacgtat agtggtcgaa agttgatcgt
     5281 cacaccaact gccagactga tcagtgtcag aaataggctg aacaatccag catattccat
     5341 ccactgccat ctcgaatttt tcatattaga agctccattc atccagtgat tgtttcacat
     5401 aggtagctgg gataggcaac ccaggtacat cttcttcttt tgtaaaacct gataaaacga
     5461 gcaaagtatc tatattattg cgtatcccag cttggatatc tgtttcatag ttatctccaa
     5521 ccatgattac ttcttctttt tgcagcccta atacttcaac ggctttatcc ataatgatgg
     5581 cttctggttt tccgatgtag atcggcggcg tttgggttgc tgtctctaca aaagagatga
     5641 ctgaccctgc tccaggaaga aggccgcgtt cagtaggtat attcttatct gggttcgttc
     5701 caatgaaagt agcacctttt tgaatagcaa gtgttgcttt aactactttt tcataggtca
     5761 gataattatc taagcctacc actacatagt caggagcctc ttcttcccat gtaaatccgg
     5821 cagctaaaat caagtcaatc aatcctgctt ctccgataac atagactttt ttcccttttc
     5881 catctgcttt cataaaatcg attgttgcca aagtagctgt gtagactgtc tctggagcta
     5941 catgaatgtc aaactcatct gctagacgat tagctactgt ttctggtgac ttagtcgtgt
     6001 tattggtaac aaacaagaaa ggtaattttc ttttttgcaa ttcttccaca aatcgtttac
     6061 cggccggtat gggttgtgtc ccacgataaa tcgttccgtc taaatcaatt aaatatcctt
     6121 tatagtccat tcatccacta ctcttccctt tttctgatcg taaatgctgt ttttgttttt
     6181 tctacttgtt taggttgttc ttgttttttt actttttcag aggtttttgc tgactctgtt
     6241 tttcgatttt taataaccgg ttttttgcga ttagatgcga ctggtccttt tttctcatcg
     6301 atatacgcac gattatggtt ttttttcttt tttcggcgct gagttgtctt ttctttttta
     6361 ccgccgattc tctcgatgac aaaatacgca caaccaaaat tgcaatattc gtaaagatag
     6421 tcttccaagg aatcgattcg ctgatctgga tgcgcccgtc gattatccgc ttggaaaaat
     6481 ccttttaggc gtagttgttc ataaccccaa tctcctacga tataatcata tcgggctagt
     6541 acatcactgt aacgttctcc aagcttttct gcattaaatc cttcacgata atcggacaca
     6601 agccgataat gtctttcacc tatcaaaaaa ttactgtcat ctaacagtgt cactagctcg
     6661 cctttgactt tttctgcttt aggctcctca acgatttctt ccaaagcagc tgtcagttct
     6721 tcggtgactg ttgtttcctg ttcagctgat gattttttct tagcaatttc tgttttatgc
     6781 tcaacgttct gctgttcatt ttgttttgca gacatgcgtt caccacctat cttttttatt
     6841 ataccttgtt tttatttgat tgggtagtga gctttcaagt aatctcctac cacacttcgg
     6901 ataaattcag ggaacaaaaa ttcatttttt ccagcaatct caatcgttgg aaaaaatgga
     6961 acaaacatca aatgatctac ggtagtaaaa gtataatttt tattcagatc gattggcttg
     7021 ttcttccaaa agacttgatg gttaatagaa tcatatgtga ttccattata gaccatctgc
     7081 ccaaaaatct taccgcgaaa tcccattccc ttcataggat agttacgtaa aaagttacga
     7141 tttttttcta tttctaaaac taagcggatc agatcatttc cacccaatgt gacatttaac
     7201 aagtgcatcg gatgcggcaa cgcagtgtga agctgatcct gattgacccg cccttttgga
     7261 atttcagtta aaaacagacc actgtttaat attgctgctt ccgtctttcc tcgttctttc
     7321 accgcctcaa aggctacttg gataaacgaa tgctcattga agatatctag actcagagaa
     7381 aatggcaaat ctgctacttc tttttctttt aataattcat gcccacgttc tagacaacta
     7441 tttatttctt gttcatcttc tgtaaaagct gtcattgttt cggtagggat ggctttggct
     7501 gaatgcttaa ggattttttt ctcttcatcg atggttaaat ggacttcacc gacatactgc
     7561 ccgtactttc cagcggctgc tatttggaca tcattgatta cgtgaccttc tctgaataaa
     7621 tgatgggtgt gcgatcctaa aataacatca attgctggta tttcttttgc aatttggaaa
     7681 tcatcctgaa tcccgagatg actcatcaaa actaaaacat ccacttgtga acgtaaatct
     7741 tcgactaatt ctggcaaaat atcataagga ttccgtatgt cccagccatt cggattataa
     7801 gtaagcggaa atggagcagt aaatgcaatt agtccgattt tcgtctggtg tttcgttgta
     7861 atgattttat atggtttcgt ccatgccggt ggctggagcg tatttttatc gaataagtta
     7921 tccaggatga tatcaaactc agcatgatcg tataaatgat tcaactcttc tttggaattt
     7981 cctacgcctt cattgtttcc tatcgtcgct gcatcataac caacttcatt catcagcaag
     8041 atattttcct gtccattcgt tgcttctgac aatggatgcc aacgatccac aaaatcacct
     8101 agatctactg caatcgttgt cgttttttct ttcttttcgt tttctcgttt acgttgatcc
     8161 aaaaaccttc tgatccttgg ccaattttct aaatgagaat gcagatcatt cgtatgtaaa
     8221 atcactattt tttccatgta ccctctcgcc tctctttatc tttatcatac cataggcagc
     8281 tttttcttcc attgaaacaa gctctatttc agagtttttc ctgccttgaa gcaaattgta
     8341 taagtacaat attcgataaa tcagtctggc taaaaaatca ggaacattca tttttacagt
     8401 actataaaaa taaaaaaaac agacccgaaa gtctgttgtc gtttcattat aatcagacac
     8461 atggcggaac ctgcttagtg ctgcttcctt ccagacctga cacgcttcac aagcccacca
     8521 ttgtcctagc ctttcggcaa agaatagtat accttatttt tcattcgttg accagtcttt
     8581 ttttaatttc ttttttcgct ggcggagctt tcggaaaaag tcagtcaaaa tcatcccaca
     8641 ttcgtcttct aaaatgccac cttctacata tgcttggtgg ttaaaccgct cgtcctccaa
     8701 aagattcatc aaggtaccgg ctgttccgcc ttttggatca tacgcgccga aataaacttc
     8761 tgctacacga gacaaaatca tcgcgccgct gcacatagga caaggctcta aggtaacaaa
     8821 aagtgcagca tcttccaagc gccagcttcc cactttttca caggcttcct tgattgcaag
     8881 catttctgca tgtgtagtag catcttgcgt ggtttctcta aggttatatc ctcttccaat
     8941 cacttttcca tccaatacaa ccactgctcc aatcggaact tcatgaagca tttctgcttt
     9001 ctttgcttct gccaatgcaa ggcgcatcca tttttctttt tctactgcat caagatttgt
     9061 atttaccaat tacccttccc tgcctttgtt ttttcttgtt ttactttagc atatgataaa
     9121 aaggctgtaa ctaacttttt ttctatggta aaataaatac aagaggtgaa caagatgaaa
     9181 atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc agcatcagaa
     9241 gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca agattcatta
     9301 tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga tcaaaaaaaa
     9361 cacccatggt atcactatct ttttaaagat gcttcttgtg ttcaagaaaa aagctttcgt
     9421 ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg gcaagatact
     9481 attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac agatgcgctc
     9541 ttagtcgaac aaataaaccg tgattatctt gatgctactg aaatcaacgg tatttttcta
     9601 tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt ccattcacct
     9661 ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac agagcaaaac
     9721 aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca ttactataca
     9781 aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat caaacaaaat
     9841 gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag ctctgctgca
     9901 aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt tcaagaacag
     9961 tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt attgcttcat
    10021 gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca accccttatt
    10081 tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac aaaatgcatt
    10141 agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac agagattttc
    10201 ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc actatctgaa
    10261 agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata gacgaatttt
    10321 tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc cgatacaacg
    10381 actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac ttttgttgat
    10441 gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac aaaaaaataa
    10501 acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt tactgttcct
    10561 tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac ccatccttga
    10621 ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt ttgagtgatc
    10681 ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata gctaggttca
    10741 aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt taaaccatcg
    10801 agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa aagtcttcca
    10861 gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg ctcttttgtc
    10921 atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt ttgtccatga
    10981 aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca tatacgtatt
    11041 gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac ggattgagtc
    11101 aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat gatctcttca
    11161 ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt ttttagcatt
    11221 tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg agattcttct
    11281 gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga acaaggagca
    11341 tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc gggtgcatga
    11401 tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa aatcttcgca
    11461 cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg agcagctaat
    11521 tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc gggttttgct
    11581 gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata cccagcttga
    11641 tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta gggagcgggt
    11701 tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt tagtggattc
    11761 caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc ggatgcttct
    11821 tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt cgcttcctcc
    11881 ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata aaggtggctg
    11941 atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt tccaagtatt
    12001 catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa tcttgagaag
    12061 aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc gacttttctt
    12121 ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat agcgaatcca
    12181 tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa aaaaaatctt
    12241 tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag tagttttcaa
    12301 aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat ttgaaatgtg
    12361 tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca gtaattgact
    12421 tcattccata ttcttccacg tataccatac ttttgaacag caaatattct ttactataat
    12481 ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata aataaataac
    12541 ataaataatt ctaaa
//
LOCUS       DAZAOD010000076        12456 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000076 DAZAOD010000000
VERSION     DAZAOD010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.078"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            38..262
                     /locus_tag="ACHDPO_002096"
     CDS             38..262
                     /locus_tag="ACHDPO_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HFN3369710.1"
                     /translation="MSFDYSKLSGRIVEKYGTQYNFSIALGLSERSLSLKLNNRVPWK
                     STELQKAIELLDIPKEEIGEYFFNLEVQNV"
     gene            286..1047
                     /locus_tag="ACHDPO_002097"
     CDS             286..1047
                     /locus_tag="ACHDPO_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HFN3369711.1"
                     /translation="MNTQKFENNLFELEVKTENGESLFNAETVARSLGFVETKNGKEY
                     VRWRTVNGYLKKYLSQEVAKNDFISEPMVYKLAFKANNVLAEKFQDWLATEVLPQIRK
                     HGMYATDELLNNPDLLIEVATKLKEERTLRLIAEQRVNELQPKADYYDRILNNKGLVT
                     VSTIAKNYGMSAVSFNKLLHELGIQFNQSGTWLLYSKFQDKGYTHIEPFDYEDKNGNR
                     QVKTRMKWTQKGHIFLYETLKKNNYLPMIEREQTA"
     gene            1059..1316
                     /locus_tag="ACHDPO_002098"
     CDS             1059..1316
                     /locus_tag="ACHDPO_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369712.1"
                     /translation="MNEEMSQTIKVQKMIDDLTHAIDSQADKIIKELQGQKVWDAKML
                     FKTIKFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            1408..1659
                     /locus_tag="ACHDPO_002099"
     CDS             1408..1659
                     /locus_tag="ACHDPO_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family DNA-binding protein"
                     /protein_id="HFN3369713.1"
                     /translation="MEQLALVNLSDLKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWVNSTEH"
     gene            1659..1808
                     /locus_tag="ACHDPO_002100"
     CDS             1659..1808
                     /locus_tag="ACHDPO_002100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369714.1"
                     /translation="MFSAPLIVYALGLWGSRQALIGTIVYMVWIFMGLDEAEYRAKKP
                     TEGAD"
     gene            complement(1922..2329)
                     /locus_tag="ACHDPO_002101"
     CDS             complement(1922..2329)
                     /locus_tag="ACHDPO_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369715.1"
                     /translation="MSFDNTITISIILALVALISPSITAVINNKHVESMKDKEIELQK
                     HDSKTQTIQTTFSTFLNNVGICIGSNTDKNISAVKASGYAVLPYIQNEDIEVMKIFLS
                     RFGYGNTDAEQKSLETYLIDKVLPILNKSLEKL"
     gene            2490..2714
                     /locus_tag="ACHDPO_002102"
     CDS             2490..2714
                     /locus_tag="ACHDPO_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369716.1"
                     /translation="MISVKGLGDEIFEAMMSKAQQDIKEKIISAAAQGQTSCTVRSRG
                     TTPSFLLALEDEGILNIKRRDGSVRLFWQF"
     gene            2724..2918
                     /locus_tag="ACHDPO_002103"
     CDS             2724..2918
                     /locus_tag="ACHDPO_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369717.1"
                     /translation="MKDFDSLGARQQPPNEASPVGVDWQENPLYPGDTCYLTEEGYVP
                     VDAILEYVQQHYPKIELGGI"
     gene            2921..3943
                     /locus_tag="ACHDPO_002104"
     CDS             2921..3943
                     /locus_tag="ACHDPO_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFN3369718.1"
                     /translation="MANDLTQTTQRSLDEQVISNLGRLQEQGLEMPPGYSPQNALKSA
                     FFELTNNTGGNLLQMAANNQEMKTSISNALLDMVIQGLSPAKKQCYFIKYGNKVQLMR
                     SYFGTMAVLDRVTGGADITPVVVRQGDEFEVAMDGPNMVVKKHETKFENLDNEIIAAY
                     VVIKLTNGKETTTVMTKKQIDQSWAKSKMKDSGPQKEFPEEMAKRTVINRAAKTLINT
                     SNDNDLLVQAAKDTLENEFDNDRKDITPQTEKVATLEQKFFSNKKITEPIQKEPDPIV
                     IPDDIQNEVTRVADVPAHPEIEQAHLIENEDINPIQEELIDIPDFGREEGVEDVSEFE
                     DDEYPF"
     gene            3906..4721
                     /locus_tag="ACHDPO_002105"
     CDS             3906..4721
                     /locus_tag="ACHDPO_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HFN3369719.1"
                     /translation="MSQNLKTTSTLSDENYYSNEADWQYMSTSQYKSFLKCEAAALAK
                     LKGDWAPTSDPKALLVGNYVHSYFESKEVHEAFKEENKSKMFSSRKPYGLLKDFQIAE
                     QMIERLKQEEAFMNIYQGEKETIVTGELFGTTWKGKIDCLNVEDEYFVDIKTTKDMHE
                     RKWNENYGSRETFIVNFGYVLQMAIYQELLLQQYGKMFMPIIAAVSKQTPSEAKLITI
                     DQDKMSYELIMLKENIERIVKVKNGEERPIPCGTCEYCRGNLSITGFTSMDDL"
     gene            4739..5521
                     /locus_tag="ACHDPO_002106"
     CDS             4739..5521
                     /locus_tag="ACHDPO_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369720.1"
                     /translation="MNLGYIKLYRKVTSSFVWTNSDMFKLWILCLMKASHEDRKFLFN
                     GQEVRLTSGQFVTGAHAIAKEYNEGVPSDKAIAWRTLWRWLKKFENEELLTIQSNARY
                     SVITIINWSDYQSSDKPVTSDGQSSDKPVTTNKNDKNDKNDKNNNPRNSRKTREYADD
                     DPNKKLAILLLKLIRKNRSLKEPDLNKWANTIRLTIEADKRTGKEVQDMIVWATNHDF
                     WSTVISSPTSLRKNFDTMVGQKNKRKQQNISNDELPETGEDW"
     gene            5521..6369
                     /locus_tag="ACHDPO_002107"
     CDS             5521..6369
                     /locus_tag="ACHDPO_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3369721.1"
                     /translation="MNKKLSAMAAPYGGLKTADHNCPKCGDPLYIWKTKNKDGTDRCG
                     PTCINKICGYREMVTKNQKEAIQKANEAMKKDAINRMLNSSMITDDAIWTFDFDGYKV
                     VDQETAQIKAMAQEWAKKIVNGSTIHAVITGRTGAGKTHLGAAVIKEVMRASNYKIAC
                     SFISYRELLEQLKFAMNDPEARKAVTGSLMAEIKKSDFVVIDDLGAELGRMEENNQAT
                     PYDVDVLTSLTEARLNKATIFTTNLSSKQLKHAYGERVFSRVMNGTKGNIAVFKTTTD
                     KRRNPV"
     gene            6366..6608
                     /locus_tag="ACHDPO_002108"
     CDS             6366..6608
                     /locus_tag="ACHDPO_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369722.1"
                     /translation="MTFVVKKMCYLDSRGRGEASVEFAKHHTTKEEADLVASVCGGEV
                     VEVIKPKRRFSKPKTKPVKKECCCPKSNQAWMRGAK"
     gene            6751..7119
                     /locus_tag="ACHDPO_002109"
     CDS             6751..7119
                     /locus_tag="ACHDPO_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HFN3369723.1"
                     /translation="MATRSKYGNKKHEVDGITFDSITEAEYYDLALWQAQANGWKVKL
                     QERFELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQ
                     YQVPLILAKKYRNTFKEERF"
     gene            7134..7295
                     /locus_tag="ACHDPO_002110"
     CDS             7134..7295
                     /locus_tag="ACHDPO_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFN3369724.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            7292..7618
                     /locus_tag="ACHDPO_002111"
     CDS             7292..7618
                     /locus_tag="ACHDPO_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369725.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            7615..8430
                     /locus_tag="ACHDPO_002112"
     CDS             7615..8430
                     /locus_tag="ACHDPO_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005743 - mitochondrial inner membrane
                     [Evidence IEA];
                     GO_component: GO:0035632 - mitochondrial prohibitin
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HFN3369726.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            8432..8557
                     /locus_tag="ACHDPO_002113"
     CDS             8432..8557
                     /locus_tag="ACHDPO_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369727.1"
                     /translation="MGFFMAKILLFLGLVGAAYLVYALLSQTDDKEDDNNDEMKF"
     gene            8569..8880
                     /locus_tag="ACHDPO_002114"
     CDS             8569..8880
                     /locus_tag="ACHDPO_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFN3369728.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEGS
                     K"
     gene            8877..9122
                     /locus_tag="ACHDPO_002115"
     CDS             8877..9122
                     /locus_tag="ACHDPO_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369729.1"
                     /translation="MIKKLIQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            9119..9535
                     /locus_tag="ACHDPO_002116"
     CDS             9119..9535
                     /locus_tag="ACHDPO_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFN3369730.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIYENSELLEVE"
     gene            9532..9870
                     /locus_tag="ACHDPO_002117"
     CDS             9532..9870
                     /locus_tag="ACHDPO_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369731.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMYGNSESAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            9867..10097
                     /locus_tag="ACHDPO_002118"
     CDS             9867..10097
                     /locus_tag="ACHDPO_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369732.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            10104..10307
                     /locus_tag="ACHDPO_002119"
     CDS             10104..10307
                     /locus_tag="ACHDPO_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HFN3369733.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            10304..10600
                     /locus_tag="ACHDPO_002120"
     CDS             10304..10600
                     /locus_tag="ACHDPO_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369734.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            10677..11090
                     /locus_tag="ACHDPO_002121"
     CDS             10677..11090
                     /locus_tag="ACHDPO_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFN3369735.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            11103..11489
                     /locus_tag="ACHDPO_002122"
     CDS             11103..11489
                     /locus_tag="ACHDPO_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369736.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            12040..12267
                     /locus_tag="ACHDPO_002123"
     CDS             12040..12267
                     /locus_tag="ACHDPO_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369737.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMLREAT
                     PKEIDQYKLVLIGIGWFKDEHIQTNMKRWLR"
     gene            12264..>12456
                     /locus_tag="ACHDPO_002124"
     CDS             12264..>12456
                     /locus_tag="ACHDPO_002124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369738.1"
                     /translation="MKLYYVEKANCWVVEGCLSKYATDIISTQFSELGLKVIFCGEFV
                     SVKEAVLPMTAKSRRSRGSS"
BASE COUNT         4530 a         1935 c         2790 g         3201 t
ORIGIN      
        1 agttcaaaac atttgaacta gaaaggagcg aactaatatg agttttgatt attctaagtt
       61 gtcgggaaga attgttgaga aatatggaac gcaatacaat ttttcaatcg ctttaggttt
      121 gtcggaaaga agtttgtcat taaagttgaa taaccgagta ccatggaaaa gcaccgaact
      181 tcaaaaagcc attgaattgc tagatattcc aaaagaagaa attggcgaat atttttttaa
      241 tttagaagtt caaaatgtct gaacttaaga aaggaattcg aaaaaatgaa cacacaaaaa
      301 tttgaaaaca atctatttga attagaagtt aagacggaaa atggtgaatc gttatttaat
      361 gctgaaacag tagcaagaag tttgggtttc gtggaaacaa aaaacggtaa agaatatgtt
      421 cggtggagaa ctgtcaatgg atatttaaaa aaataccttt cgcaagaagt tgcgaaaaac
      481 gactttatca gtgagccaat ggtttacaaa ttagccttta aagcaaacaa cgtacttgct
      541 gaaaaattcc aagactggtt agcaacggaa gtcctacctc aaatccgaaa acacggcatg
      601 tacgcaacag atgaactact taacaatcca gacttgctga ttgaagtagc aaccaaactc
      661 aaagaagaac gcacgttacg attgatagct gaacaacgag taaatgaatt acaaccgaag
      721 gcagactatt acgaccgaat cttgaacaac aaaggattag ttacagttag tacgattgct
      781 aagaactacg gtatgagcgc tgtatcgttt aataaattgc tacatgaatt aggtatccag
      841 ttcaatcaaa gtggcacatg gctgctatac agtaagttcc aagacaaagg atacacgcat
      901 attgagccat ttgattatga agataaaaac ggcaatcggc aagtaaaaac aaggatgaaa
      961 tggacgcaaa aaggacacat cttcttatat gaaacattga agaagaataa ttacttaccg
     1021 atgattgaac gtgaacaaac agcataggag gtaacactat gaacgaggaa atgagccaaa
     1081 caatcaaggt acaaaaaatg atagatgatc taacacatgc aattgatagc caagccgata
     1141 aaatcatcaa ggaattgcaa ggacaaaaag tttgggatgc aaaaatgctt ttcaagacta
     1201 tcaaatttga aatgaatcca acaaaaagaa agctcgccga tgtgttggaa gaaaagttgg
     1261 cttccgctat caacgagcaa gaattactat ttgaaaccga tacttttaac agctgatgtt
     1321 ttatagatga cagtttcatc cgaatctata tcattataga ttcgattatt gcaatgtacg
     1381 aattataaat acaggaggaa ataaccaatg gagcaactag ctttagttaa cctctcagac
     1441 cttaaagctt ctttggcaga atctgagatt gcaaatgaag tgtgggatac aaagcaagct
     1501 gcggaatatt taaaaaccac aacacgcacg ctgactaaag atgccgaatc tggaaagatt
     1561 ccagcagcga aagttggcag agagtggagg tttagtagta tcgctttgta tcagtatcta
     1621 aaaggaggaa aaacatgggt aaattcaaca gagcactagt gttcagcgca cccctaatcg
     1681 tctatgcttt aggactttgg ggaagcagac aagcattaat cggcacgatc gtttacatgg
     1741 tttggatttt tatggggctt gatgaagctg agtacagagc gaaaaagccc accgaggggg
     1801 ctgactaaag tgtggttctg tttattaggt gtttatctcg tggccgtttt agtaaataac
     1861 tacatgagaa aacgtggcga atactggtat acatcctatg cggttctagt atgtctaatg
     1921 cttacaattt ttctaatgat ttattcaaaa taggtaatac tttgtcaatc aaataagttt
     1981 caagagattt ttgttctgca tcagtgttgc cgtaaccaaa acggcttaag aaaattttca
     2041 taacctctat atcttcattt tgaatatatg gcaggactgc ataacctgat gcttttacag
     2101 cagatatatt tttatcagtg ttactaccaa tacaaatacc cacattgttg agaaatgttg
     2161 agaaagttgt ttgtattgtt tgggtttttg aatcgtgttt ttgtaattca atttctttat
     2221 ccttcatcga ttcaacatgc ttattattta taaccgctgt aatcgaaggg gatataagag
     2281 ctactaaagc taggataatc gaaattgtga tcgtgttatc gaaactcatt ttttcaccat
     2341 ccagttttta aaccattata tcaaaaagga gagaagaaat aatgcaagaa ttagtaattt
     2401 tgaaaaataa aaaaagacac gaacgccagc aagcatgatc gtgtccaaaa gaaaaatctt
     2461 ttaaaccatt ataacacagg aggaaataaa tgatctcagt taaagggtta ggcgatgaaa
     2521 tattcgaagc aatgatgagc aaagcacaac aggacatcaa agaaaaaatc atttctgctg
     2581 cagcgcaagg acaaactagc tgcactgttc gatcgagagg aacgacacca agttttcttt
     2641 tggcgctaga agatgaaggc attttgaata tcaaacgaag agatggcagc gtcagattgt
     2701 tttggcaatt ttaggaggcc gtgatgaaag attttgattc tttaggcgcc agacagcaac
     2761 caccaaatga agctagtcct gttggagttg attggcaaga aaatccgtta tatccaggtg
     2821 atacttgcta tctaacagaa gaaggctatg taccagtaga cgcaattcta gagtacgtcc
     2881 agcaacatta tccaaagatt gaattaggag gaatttagga atggcaaatg atttaacaca
     2941 aacaacacaa cgttcattag atgagcaggt aatcagtaat cttggacggt tacaagaaca
     3001 aggtttagaa atgccaccag gatatagtcc acaaaatgcg ttaaaaagtg cttttttcga
     3061 actcactaac aatacaggag gaaacttgtt gcagatggct gcaaacaatc aagaaatgaa
     3121 aacctccatt tctaatgcac ttttagacat ggttattcaa gggttatctc cagcaaaaaa
     3181 acaatgctat ttcattaaat acggaaacaa ggttcagcta atgcgttcat attttggaac
     3241 aatggcggtc cttgatcgtg taactggagg ggcagatatt acgcctgtag tcgttcgaca
     3301 aggtgatgag tttgaagttg caatggatgg accaaacatg gttgtcaaaa agcatgaaac
     3361 aaaattcgag aatttagaca atgaaatcat tgcagcctat gtagtcatca agttaacaaa
     3421 tggtaaagag accacaacag tcatgacgaa aaagcaaatc gatcaaagtt gggctaagtc
     3481 aaaaatgaaa gattctggac cgcaaaagga atttccagaa gaaatggcta aacggacagt
     3541 aatcaatcgg gcagctaaaa cattgatcaa cacaagcaac gacaacgatt tattagttca
     3601 agctgcaaaa gatacgttag aaaatgaatt tgacaatgat cggaaagata taacgccaca
     3661 aacagaaaaa gtggctactc tcgaacaaaa attcttttca aacaaaaaga ttactgaacc
     3721 aatacaaaaa gaaccagatc cgattgtgat tccagatgat atccaaaatg aagtaactcg
     3781 agttgctgat gtacctgccc atccagaaat agagcaagca catttgatcg aaaatgagga
     3841 tatcaatcca attcaagaag aattgataga tattccagac tttggacgcg aggaaggtgt
     3901 agaagatgtc tcagaatttg aagacgacga gtaccctttc tgatgagaat tattactcca
     3961 atgaagctga ctggcagtac atgtcaacat cacaatataa gtccttttta aaatgtgaag
     4021 ccgcagcctt agcaaagttg aaaggcgatt gggcaccgac gtcggatccc aaagccttac
     4081 tcgtaggaaa ctacgtacat tcttattttg aatcaaaaga agtacatgaa gcgttcaaag
     4141 aagaaaataa atccaaaatg ttttctagta ggaagccgta tggattgttg aaagatttcc
     4201 aaattgctga acaaatgatt gaacgactta agcaagaaga agcattcatg aacatttatc
     4261 aaggtgagaa agaaacgatc gtgactgggg aactatttgg aacgacatgg aaaggcaaga
     4321 ttgattgctt gaatgttgag gatgagtatt ttgttgatat caaaacaacc aaagacatgc
     4381 atgagcggaa atggaacgaa aactacggat caagagaaac gttcattgtc aattttggtt
     4441 acgtacttca aatggcaatc tatcaagagc ttcttttaca gcaatacgga aagatgttca
     4501 tgccaatcat cgctgcggta tcgaagcaaa cgcctagtga ggcgaagttg ataacgattg
     4561 atcaagataa gatgagctac gagctaatca tgctaaaaga aaatattgaa agaattgtca
     4621 aagtgaaaaa tggcgaagaa aggccgatac cttgcggtac gtgcgagtat tgtcgaggta
     4681 acctttcaat tactggattc actagcatgg acgatcttta aaaggaggtg ctttgcgaat
     4741 gaatctagga tacatcaagt tataccgtaa agtgactagt tcattcgttt ggaccaattc
     4801 cgatatgttc aagctatgga tattgtgttt aatgaaggct agtcatgaag atagaaaatt
     4861 tttatttaac ggtcaagaag tacgtttgac aagcggacaa ttcgtcacag gagcccatgc
     4921 aatagcaaaa gagtacaacg aaggagtccc gagtgacaaa gcaattgcat ggcgaacgct
     4981 atggagatgg cttaagaaat ttgaaaatga agaattattg acaatccaat cgaacgctag
     5041 atatagcgtt ataacaataa taaattggtc tgactatcaa tcgagtgaca agccagtgac
     5101 aagcgacgga caatcgagtg acaagccagt gacaacaaac aagaatgata agaatgataa
     5161 gaatgataag aataataatc ctcgcaactc tcgaaaaaca cgagagtatg cagatgacga
     5221 tccaaataaa aaattggcca ttcttttatt aaaactcatt cgaaagaatc gtagtctcaa
     5281 agaacccgat ttgaacaaat gggccaatac gattcgtttg acgattgaag ctgacaaacg
     5341 aactggaaaa gaagttcaag acatgattgt ttgggctact aaccatgatt tttggtccac
     5401 agtcatttca tcgccaacta gcttaagaaa aaatttcgat acaatggtgg gtcaaaaaaa
     5461 taaaagaaag caacaaaata tttctaatga tgagttacca gaaacaggtg aggattggta
     5521 atgaataaaa aactaagtgc aatggctgca ccttacggcg gattaaaaac agcagatcat
     5581 aattgcccga aatgtggtga tccattgtat atctggaaaa caaaaaataa agatggtact
     5641 gatcgatgcg gtcctacatg tatcaataag atttgtggtt atcgagaaat ggtaactaaa
     5701 aatcaaaaag aagctatcca aaaagcgaat gaagcaatga aaaaggacgc tatcaatcga
     5761 atgcttaaca gttcaatgat tacagatgat gccatatgga ccttcgattt tgatggatac
     5821 aaagtagttg atcaggaaac agcacaaata aaagcgatgg ctcaagaatg ggctaaaaaa
     5881 attgtaaatg gtagcacgat tcatgcagtg ataaccggta gaacaggagc cggcaaaacc
     5941 catctaggcg ctgcagtgat taaagaagtc atgagggcat ctaattataa aattgcttgt
     6001 tcatttatca gttatcgaga acttttagaa cagttgaaat ttgcaatgaa tgatccagaa
     6061 gcaagaaaag ccgtaacagg ttcgctgatg gctgagataa agaaatcaga tttcgtggta
     6121 atcgacgatt tgggtgcaga actaggaaga atggaagaaa acaaccaggc aacgccttat
     6181 gatgttgatg ttctcacatc gctcacagaa gctcgtctaa acaaagctac gatattcaca
     6241 accaatttat catcgaagca attaaaacac gcgtacggtg agcgagtgtt ctctcgtgta
     6301 atgaatggaa cgaaagggaa catagctgta ttcaaaacaa cgacagacaa aaggaggaat
     6361 ccagtttgac ctttgtagtg aaaaaaatgt gctacttaga tagccgaggg cgaggagaag
     6421 ctagtgtcga gtttgctaaa caccacacga ctaaagaaga ggctgacctt gttgcaagtg
     6481 tttgtggcgg cgaagtagtc gaagttatta aacccaaaag acgattttca aaacctaaga
     6541 caaagccagt gaaaaaagag tgttgttgtc cgaaaagtaa ccaagcatgg atgagaggtg
     6601 caaaatgact tgtttaaaat gcaacgatga aacagttatt tggtataaga cattgcttgg
     6661 atggtcaact tgtgaacctt gtccaatatg caatgaaaat ggacgacgtt cgaaagaacg
     6721 actcgaaaga ctaaagaagg agtatagcaa atggcaacaa gaagcaaata cggaaacaaa
     6781 aagcacgaag tagacggcat cacttttgat tctatcacgg aagcagagta ttacgatcta
     6841 gccttgtggc aagcacaggc gaatggttgg aaagtgaagc tccaggaaag gtttgagctg
     6901 atgccgaagt ttgaactaga gggcaagaag tatcgcaaga tcgagtatat tcccgacttc
     6961 acattttaca aaagcggcaa gctggtcaaa gtcgtagatg ttaaggggat gcagacaaaa
     7021 gactttaaga tcaaggcaaa gttgttctgt catcaatatc aagtgccgtt gatattagcc
     7081 aaaaaatatc ggaatacgtt caaggaagag cgtttttaac gaggtggtcc atcatgacaa
     7141 cagaagaagt gattcaaatg cgaattcgaa gccttcggcg tgagattgac gatctggaac
     7201 gaacaaaggc agtgatggtc aatgaaacgg ctagaaaggc aatcgatttg cacatagaga
     7261 atttaagaag ggaaatccgt agattggagg aatgagcgtg gataaggaag cggcttggcg
     7321 aaaattaatg ttgctgattc aagatgagaa ctggcaagaa gatgaagcag tggttgctga
     7381 agttcagcgt ctaggaaaga ttgctaacgg acgtatacga aaaaagccag acaaaagaaa
     7441 acagcgcaaa gggaaaatcg tcgttgtttt acacgaaggc aaaattttga tgcaaggaac
     7501 agctagtgag ctgtctgcag aaactggata tacgcgtggg actattcgaa cgtacgcttg
     7561 gcgaaatcac accgatcgaa aagggcacga atataagtat ttggaggaag aaaaatgaac
     7621 gaaaacaaat taatcaaatt gggtgtagca ggagcagtaa tcgtaggtat tggagttatc
     7681 ggaggattta agttcttcga aaaaatcgat aatggatatg tgggtgtgcg ctattcaatg
     7741 aacggcggta tcaaagatga agcactgacg caaggtgtga aatttgtagg gattgacaaa
     7801 gtgatccaat atccaattcg cttgcaaact atccaatcaa aaaatatttc agtatctaca
     7861 agcgacggca aaaagacaac gattgatatc aaatatgact acaaagttga ttcaactaaa
     7921 gcagcaaaaa tgtacaagga atttgggaat atcacttcgg aagatatcga aagtggatgg
     7981 ttaaaatcta agcttcaaaa ggtcgctcgt gaagtttatg cgaaatatag tctgcttgat
     8041 gtcctttcag gagattcctc taaagttgaa gctgaggtat taacgaactt tgctaaatca
     8101 gttgaatcta aagggtttga agtcgaagac gtaacacttg gtgttccaga tgtcgataaa
     8161 gaaacacaaa aatcaatcga tgcgatcatt cgagctggtc aagaaaatga aaaagcgaag
     8221 ctagacgcag aaactgcaaa aactcaagct gatagtgaag cttacaagaa aacaaaagct
     8281 gcagaagcag aggcagaatc taatcgcaaa gtcgccgaat cagtaacaga caatttgatt
     8341 cgttatgaag aagctcaagc tcgcaaaaag catggatggg taacagtaaa tggagcagat
     8401 actgtagtta cggatgaagc aggcaaataa tatgggattc tttatggcta aaattctctt
     8461 gttcttaggt ttagtaggag cagcatatct cgtgtatgcg ctcctttccc aaactgatga
     8521 caaagaagat gacaacaacg atgaaatgaa attttaggag gagaaataat ggacgaacta
     8581 atcacaaaag tagagcagtg ggctaaagac aagggactgg atcaagcaga tccaaaagca
     8641 cagtttttga aagtagctga ggaattcggg gaaatagctt cggcgatggc aagaagtaat
     8701 gatgaactat ttaaagatag cgtaggagac gttatcgtca cgctgattat cctttccatg
     8761 caaaaaggga caaacgtaca agagtgttta gaaatggcat acaacgaaat caaaggacgc
     8821 acagggaaaa tggtagatgg tgtattcgtg aagtcgagtg atttggaggg cagcaaatga
     8881 taaaaaagct cattcaattc agcatggatt tatatgatat cgaatcagga gcaacactat
     8941 ctgtggaatc ggaccatcta atcataaatt ttggtggaaa gcgccagatt attttgtggg
     9001 tagttgatga tgtactgttt ccagaaattg ttcatgattt cgaagaatca aaagcggttg
     9061 agtttgaaat agtgaaaaaa gtaatggaat tgattgaaaa atacgaggag gacagcgaat
     9121 gataccgaag tttagagcgt gggataaacg aaagaacgta atgagagatg tagccgtctt
     9181 gcattttact aaaaacggca aaacaaactt tattgaatat tggataaatc ctaccgaatt
     9241 gaaatcatat cacgtgcgaa acatcgacct catgcaatcc acaggaatga aagataagaa
     9301 tggtgtggat atatttgaag gggatatagt attagtcagc gtgcgaaatg gcttcgatta
     9361 cttagataat aaagtttgta ttgtcaaaaa ttcaatagat tattccggat tagtttgtgc
     9421 cactgttgat gaagacttag agtatcaaat ttttaacaca gagctgtttg aagaatacac
     9481 gtatgaagtc atcggaaata tatacgagaa tagcgagtta ttggaggtag agtgattatc
     9541 ttagctactg actacatcga ttctttaaaa gatgaaaatg ggaatgtccc agcattgcta
     9601 aattgtggaa ttaaaagcaa gaatagaatc attttgttac ggatatcggc tgatttagca
     9661 aaatatcttt atctgagcaa gacagcagta tattacactg cggctacacg ttatcagtac
     9721 aagggaaaaa caatcagtca ggattattat gatcgtttaa tcagtcctga tatgtatggg
     9781 aattcagaat cagcaattaa gctgtttggc gcaatagaga tatatgccga tgattttcca
     9841 aatttatggt tgaaggagga agcggaatga aatacgaaat accactaagt gaagcagacg
     9901 tccagtcaat tattaacggt cgggaggtta ataaaaaact tcctgatggt actgaattag
     9961 tcatcagaca aagttatttg aaagatatgg cagctccagt attaattgat cgttttaacg
    10021 tgactgattc tgtggtagag aaccacttga aagaatttcg atcaagtata aacgacactt
    10081 tcagattagg gagttgattg acaatgaaca ccagacaccg cagagtagca aaactaagaa
    10141 aacaggaact gaatgtacta aagacaaagt ttgaaaaaga atatggaatt tcagcagaag
    10201 aaacatataa agtggcaagt cagtgtgttg ctgatgcaag tgatgctatt cgtaagtttg
    10261 gaatttcgat attaagtgat gatcgtaaat gggaggaaaa agaatgaaac taaaagacgg
    10321 attttacgct agcagtcacg gtatcggcgg tttaatgcta gatatgccga caaagaatcc
    10381 taaaacacgt aagaaaccaa aagtcaaagt cggtgacatg gtccgctgtg aagcagagga
    10441 gttcatttat ccatttcgtg gatatgtaga acacgtctat aatcactcag cgatcattcg
    10501 cattgaaaac acgatggaat gtgataaatg gacagctaaa agcaaagaga atttagcagt
    10561 agtgagattg gtggatatgg aactaatcaa tgacaaataa aaaagccgga tcgctccgac
    10621 taacataata aaacagacaa gtttattata tcacataaaa ggagcagttt gaattgatgc
    10681 aattgttacg agaggtagat ttcaaacaga caagatgtaa tgcgagagat gtgctgaaga
    10741 actttcggcg tttggagcgg atggcaggtc gctctttgat agatattaag tcgccgatta
    10801 ttacggatat gccgaaggca ccgaagcacg gcaataaggc agaggatgca ttgattcaga
    10861 tgatggatat agaagcggag agagacgcga ttttagcggc tttgatggct cttagtctga
    10921 ttagtcgtca gatactctac tacagttttt gtgtgccaga cagcttctca aactacagaa
    10981 ttagccgtga agtgggttat tcagaaagaa gtatacaacg gatgaaatcg gaagctctaa
    11041 tagagtttgc agaagcatat aaacacggaa gaataattgc ttataaatag ggggaccata
    11101 taatgtggaa agattatgta tcgttgaaag agttgaaaaa agatcttgtt ttcaaaagaa
    11161 ttgtagaatg gtcagagagt gaattaattt tagaagatgg aaccaaaatg gaagttgtat
    11221 gtagcgaatc agattgctgc gcatgggccg aaggtgaatt caaaaatgta aagcttgatg
    11281 cagtgattac agatataaag atttttgata aaggtaaccg tctctataat ggtgacggac
    11341 atacctctta tgctgaagtc gttgtttatc ataatcgtaa tgagatcgct aaagcagaat
    11401 gcacagcgaa tgatgggaat ggcggctact attatagtgt ttgtgcttta aaggtcaaag
    11461 acaaactttg tatagtgact gacgcataaa aaaatggcgg ttttttggcg gaatgatggc
    11521 ggtttttagc catttatcag tgatattatg gtagtgtcga aagattagtg ataggtctga
    11581 gacaaaataa taataaaagg aacatcgttt tattattgtt tcacaattaa gcttcgatag
    11641 acagcaacgg aaatattaag aataaggatg tgaattttaa ctccttctaa attgttctta
    11701 ttatctatca tccgttgctg tttattgtta catacagatc gcttaggcgg tctttttatt
    11761 ttggccgaaa acctacattt tcgatggccg attattggag gaggaatagc atgttcaaac
    11821 tatctgaaat cattaagaag tccgacgttg agaaattaga gatgttaaaa aagaagttga
    11881 agaaatagca gtctcttcgt gaggctgttt tattttgctc acaaaaatag accactatcg
    11941 ggtaatagtg gtcaggaatt aaatgaaaaa gatgttaggg ttgttagcta agtataacat
    12001 cataacgctt acaaaacaat gcaagaagga taaattatta tgagaactta ctggtatgtg
    12061 tcattaaaca ataaatatcc gaagccaatg aaaggacagc ataggcgtgt agtcatgtct
    12121 gttcaaatga aggcgaagta ttcgattgta gaaatgctaa gagaagctac accaaaagag
    12181 attgatcagt ataagttggt tcttattggc attggttggt ttaaggatga acatattcaa
    12241 acaaacatga agaggtggtt gagatgaagt tatattatgt tgaaaaagca aattgttggg
    12301 tggttgaagg ctgtctgtca aagtacgcta cagatattat atctactcaa ttttcagagt
    12361 tgggattgaa ggttatcttt tgtggtgagt ttgtcagtgt gaaagaagcg gtattgccaa
    12421 tgacagcaaa gagcagacgc tcgcgtggtt caagtt
//
LOCUS       DAZAOD010000077        12361 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000077 DAZAOD010000000
VERSION     DAZAOD010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.079"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            112..185
                     /locus_tag="ACHDPO_002125"
     tRNA            112..185
                     /locus_tag="ACHDPO_002125"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:146..148,aa:Asn,seq:gtt)
     gene            complement(323..487)
                     /locus_tag="ACHDPO_002126"
     CDS             complement(323..487)
                     /locus_tag="ACHDPO_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369739.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            782..2110
                     /locus_tag="ACHDPO_002127"
     CDS             782..2110
                     /locus_tag="ACHDPO_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFN3369740.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2312..3145
                     /locus_tag="ACHDPO_002128"
     CDS             2312..3145
                     /locus_tag="ACHDPO_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFN3369741.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            3161..3898
                     /locus_tag="ACHDPO_002129"
     CDS             3161..3898
                     /locus_tag="ACHDPO_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFN3369742.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(4053..5021)
                     /locus_tag="ACHDPO_002130"
     CDS             complement(4053..5021)
                     /locus_tag="ACHDPO_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFN3369743.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5253..6086
                     /locus_tag="ACHDPO_002131"
     CDS             5253..6086
                     /locus_tag="ACHDPO_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFN3369744.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            6120..6959
                     /locus_tag="ACHDPO_002132"
     CDS             6120..6959
                     /locus_tag="ACHDPO_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFN3369745.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6985..7545
                     /locus_tag="ACHDPO_002133"
     CDS             6985..7545
                     /locus_tag="ACHDPO_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFN3369746.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7744..9465
                     /locus_tag="ACHDPO_002134"
     CDS             7744..9465
                     /locus_tag="ACHDPO_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFN3369747.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9630..10772
                     /locus_tag="ACHDPO_002135"
     CDS             9630..10772
                     /locus_tag="ACHDPO_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFN3369748.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10788..11999
                     /gene="thiI"
                     /locus_tag="ACHDPO_002136"
     CDS             10788..11999
                     /gene="thiI"
                     /locus_tag="ACHDPO_002136"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFN3369749.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4220 a         2066 c         2562 g         3513 t
ORIGIN      
        1 aaaataaaaa taacaaaaaa tgcgaacggt ttctttgata atataataaa aaaattcaaa
       61 aaaagtattg cgttatttag aagaaattga tattatattc atgtacttga ttccggcata
      121 gctcagttgg tagtagcgca tgactgttaa tcatgatgtc gtaggttcga gtcctactgc
      181 cggagtaaat aaagcttatg caaagaaaaa gaaatccaat cacttgggtt tctttttctt
      241 ttattattat gatgaatcaa gctttctgtt tttgtcacgt atgttgtaat ctttacgaaa
      301 gagtagagtt ggctactcat aatcaaccat acttcccatc atcgctaaat acgaaataaa
      361 tcagcattcc tacaccaatc aaagcacaag ctgcaccaag aaaagggatg acattcccaa
      421 agttatctgt attcataagt atgccaccac ccacaaacaa aaagccgcca gcaatcaggt
      481 ttttcatttt attcatctcc tttcttacgt tatagtattt ccttctttca atgagtattt
      541 tgaaagctat cttattgtat gatgttcttc taggcctctt ctttattata caggccattt
      601 tcgttatctc atagaaatat tcctttttat ctgaaaacta ttgtataccg tatgacattt
      661 ttcttcatga agttgtaagt atattctcat tcaaatgaaa atttcatcat agaagagatt
      721 gtatttctaa attcttaaga gtaaaatacg aagtataact tggatttgga aggatgattg
      781 gatgaaagct attacgcctg atatgacaac aaaatttaac aaacagtttc aagcaaatat
      841 caaacagcag gcattgcagc gggcagttgt gaagaacgga attactgctt ctgctgaaaa
      901 tgtttcagca catgtggaga atacaccggt attttctata gatttggcta cggggaaagt
      961 ggctaatcaa atgcaatcgg ggcgttgctg gatgtttgct gcactgaaca cattccgtca
     1021 taagatgctg aatcaattcc atttaaaaga gtttgaatta tcacaaaatt acactttttt
     1081 ctgggataaa tatgaaaagg caaattattt ctatgaaaac atcattgcaa caggaaaaga
     1141 ggcaatcgat agccggaaag tagctttctt actcgctact cctcaacaag atggcggcca
     1201 atgggatatg atcgtttcat tattccaaaa atatggcgtt gtgcctaaat cggtgatgcc
     1261 ggaaagtgcg aatagttcaa attctcgaga tttgaataac tacttgaaca aattactgcg
     1321 taaagatgca gtagtgttac ggaaaatggt tgctcaagga gaaacattag acgctattga
     1381 agaaaagaaa gaagaaatgc tagaaagcat ttataacttc ttagctatct cattaggaac
     1441 acctccaaaa gaattcgatt ttgagtaccg cgatgaagaa aagaactatc atcttgaccg
     1501 aggactgaca ccacaaattt tttatgataa atacatcggt gtaaaattag atgattatgt
     1561 tagcgtgatc aatgcaccaa caaaagacaa accattcaat cgttcttata cagtagagat
     1621 gctaggaaat gtcgttggcg ggaaagaagt caaatatctg aatgttgata tggaaacttt
     1681 caaaaaatta gcgattgctc agcttgaaga aggagaatct gtttggtttg gttgtgatgt
     1741 aggtcaatct tctactagaa ctagtggcat catggcctta gatgcttatt caatggatga
     1801 tctatttgat acggatttta caatgactaa agctgaacgt ttagattttg gagaaagtct
     1861 gatgacccat gcgatggtat tgaccggtgt tgacttagta gacgggcaat caacaaaatg
     1921 gaaagtcgaa aatagctggg gcgaaaaagt tggaaagaat ggcttctttg ttatgagtga
     1981 tgcctggatg gacgaatata cgtaccaaat cgttgtaaga aaagatttat tgacgaaaga
     2041 gcaattaaat gcgttcaatg aagaaccaat tgttctatct ccgtgggatc caatgggtgc
     2101 tttagcatag acgagtattt caatgaagag tatgtagtaa agataaaaag agctggctta
     2161 agccagctct ttttatcttt aaagtccatt ccctgttttt tatggtccct gtgctataat
     2221 tctaaataaa ggataaggat tggaaataat ccttttatca ttaaaaatat gatgacgaag
     2281 tagaataaaa ttgggagtag gggggaaagt catggatatc caaactgttt tatctgatct
     2341 gaaattaaat ggtaaagtga ttccagttgt tggtggcgat gttaatcaga cctatcgtat
     2401 aaaaaccgaa catcgtgctt attttttaaa aatccatccg aatgtaaaaa aaggattttt
     2461 tgaagcagaa gtagacggat taaaagaact gtcagcattc gtacgtgtac cggatacgta
     2521 tatgctaggt gaaacaagtg aaggcgctta tttgttaatg gaatggatcg agccgggaaa
     2581 aggggatcaa cgagatcttg ctgcagcttt agctaatctc catcagcaaa cagcgccaca
     2641 atttggtttt cgtaaagata actatttggg tacacttgtt cagaaaaatt cttttgaaga
     2701 agattggtgg acttttttct ttaaagatcg gcttgaatcc cagatttctt tggcagaaga
     2761 aacgaatcga tggaatgtac agcgtcaaga aaagtatctg cgatttaaag aacgtgtatt
     2821 gaaatcggtt gaaccaaaaa agatcactcc acgcctcttg cacggagacc tgtggagtgg
     2881 taatgtgttc tttgaccagc aagggcatcc agtttttgtc gacccagctg tttcttatgg
     2941 gaatcgggaa caagatattg caatgagcca gttattcggt ggtttccgac cggaattttt
     3001 agatgcttat caaactatat ttccattaga aaagggatgg aaagaccgac tgccgattta
     3061 ccagttatat tatcttttgg cacatttgaa tatgtttgga gaaagttacg gttcccaagt
     3121 agatcaatta ctagaaaatt tttaagagga gggcgtgttt ttggcaaaaa aatataccaa
     3181 aaagcatgaa gtttcatatt atgagtgtga catcaaccaa acgatgacat ttccttcgat
     3241 gttaggagta gttatcaaaa cgtctgaaga tcaaagcgac cagttgggaa gaggcagtga
     3301 attcgtcaat agctttggac ttacttgggt catcacgaat tattccatgg agattaatcg
     3361 tctccctaga gtcggtgaag taatctcagt aacgactcaa gccatggagt acaataagtt
     3421 tttctgttat cggaacttct ggatccatga tgaagatggg aaagaattag tcaaaataga
     3481 atctgttttc gtattgatgg attttgtgaa tcgaaaaatg agcagtgtta atgaagagat
     3541 cattgctcct tttgagagtg agaagatcaa gaaaatcaag cgtcaggaaa aaattgaaaa
     3601 gattgattcg ggcttcatgt tgccatatcg tgttcgtttt tatgatatcg atagtaatca
     3661 gcatgttaat aatgcgatgt attttaattg gatcattgac gtattaggat atgacttttt
     3721 gactacgcat gttccagaaa aagtaattat tcgatttgat aaagaagtag agtacgggaa
     3781 tgagatcgaa agccattttg aacaaatccc tatcgaaaat ggtgtcaaaa caaaacatga
     3841 aatccgaatg caagaacagc tgtattgtga agcaaatatt atatggaaaa ataaataaaa
     3901 aagaggttgt gacagaaggg ggcaacttca agaaataaga agaaatttac gaaaattgtt
     3961 tctcaaattt ttgtaaattt tcgacttagt tttcgaagaa gctatttttg tcacagcctc
     4021 tctttttaag tttagctatt agataatgat gtttagtttt ggataaacga aatcaattct
     4081 tcacccgaca aaccatagtt tacagcaatc aatagtttta aacgtgcttt ttgactatta
     4141 atactgttac agaaaataat ccccattttt tctagttctt ttcccccgcc ttcataatca
     4201 taaacaggct ctgcgattcc attgaaacaa cgagaaacaa gtactacagg gattttttgg
     4261 acaagaagct tttccaaagc agctaaggct tgtggaggga gattccccgc acctaaagct
     4321 tcgattacca aaccgtctac tttcgtatgg gcgatggctt ccaataagtc cccttgcatc
     4381 ccagcatatg ctttaacgat cgggatagtc ccatctacag cggaaatgtc cagtcgcttt
     4441 gtttctaaaa gttcctgcaa gaataaaatt cgattcttag ttactaagcc gatgggaccc
     4501 aatgtaggtg ttcggaaagt agcaacattt gtggtatggg tctttgtcac gtagcgtgca
     4561 gaatggatct catcgttcat gaccaccaaa acccccttat ctagcgcttc ttcacaactt
     4621 gcgacacgaa tcgcactttc aaaattataa aggccgtcac ttccaagttc attacttgaa
     4681 cgcattgccc cagtcaaaac aattggtaat ttgttgccaa tcgttgtatc aagaaaaaaa
     4741 gcagtttctt ctaatgtatc tgtaccgtgt gtgatcacca ctccggatat acctgatgca
     4801 taagcggaca agatacgttc ttttaatacc aacatgtgag aaggcatgat gtgtggtgag
     4861 ggaagattga agatatcttc aactaataat tctacatgct tggggattgt gatttctgca
     4921 tctaataatg ggtttgccac atcaggacta acaccgcccg tgagcatgtt ttctttcatg
     4981 gcgatcgttc cgccggtgtg tagtacaagt atttttttca ttttacagac ttccttacga
     5041 ataattttgc atagccgtta aatcttattg tatactatat aaaagagttt tgctatcagt
     5101 gaagaataac gaatagccta acttatcata aaaaagctga ccttattaaa atggaaaaga
     5161 ctcaaccttg acctcctaat acaatggagt atctggttga gtttctttta caagaaagca
     5221 gccaaggaaa tcaatcacga aggtggccgg aaatgatcag aatcggatta acatcgttta
     5281 aagaacatga caaattaact ggtaaaaaga ataacactct ttatgaatat gcagggtttc
     5341 tacccttagt ggaattagat actgcctatt atggaattcc ccgaaagtcc tcagttgaga
     5401 attggataag tgaagtacct gaatcatttc gctttgtagt caaagtctat caaggaatca
     5461 gcggtcaagg agactggaag ccttattatc agaccgaaga agagatgatt gcgcattttt
     5521 tagatgttat gtcgccaatg gtagatgctg gaaagatgtt ttgcttttta gtccaattcc
     5581 cctcatcatt caaatgtacg aaagaaaatg tccagtactt gcgcaaactt agaaagtggt
     5641 ttgagggtta tcctgtttct atagaattgc gggattattc ttggtacagc gatgaatttc
     5701 ttgaacgtac aagaaacttt atgtctagag ccgctttttc tttagccatc atcgatgagc
     5761 cacagttgct gaatacaacg attccttttg atccatttgt caccaatccg aactttgctc
     5821 tttttcgatt ccatggtagg aatgcgcaag gatggcaagc aaatgataaa gagtggcgta
     5881 aaaaaagaac gttatatcgt tattcagaaa aagaactgca agaactagca catgaagtca
     5941 aagtagttga ttctaagaca aaagaggtag gtgtgatttt taataataat tctggtggtg
     6001 atgcggctga aaatgcatta gcactgcaaa aaatattaaa tatcaagcca gatggactca
     6061 atccaaccca aatggatctg ttttaagggc ttattttatt caagaaaggg gcgaagtcta
     6121 tgatcaaagc tatttttttt gatattgacg gaacattggt caccaatcgt tcaaaagcgt
     6181 tggaatcaac aaaacaagca attgaatatg ctcggaaaaa cggcatttta tgcggtgtag
     6241 caacggggcg cagcccagta aagatcaaag aaatcattga tgaattggaa ttagatatgt
     6301 atgtcgtgta taatggtcaa ctggttttta ctgcagatcg cacgattatc gaccaccctt
     6361 ttgaacaaaa agtattggaa catattgttg aatttgcaga tgagaaccat cgacaaatcg
     6421 tttttggtgc gagaaatcgg ttagatggat caacgacgat gctattagga caatcgattt
     6481 ttatcaagcg actagtcagc tttttaccgc gtaaattccc ggtacgtctg atgaaaaaaa
     6541 tcctccaggt ttttagccct caccgacaaa aggatcgtta tgaaacgtta gagatattaa
     6601 aagaaccaat ttatcaatgt atattgctca gtccggagtc agaacagaaa aagttagaac
     6661 atcgctttcc cgagtgtacg tttcagcgtt caaatacgta tactgtagat atcatcccaa
     6721 aaggtggttc aaaattacta ggcatccaag ctttcgcaaa tgctgtcgaa attgaaatgg
     6781 aagaaattat ggcattcggc gatcattaca atgatatcga gatgctgaaa ggtgtaggaa
     6841 ttggagtggc catggggaat gctcagatcg aagtaaaaca tgctgcagac tttgtgactc
     6901 aatcaaatga agaagatggg atatacgaag gactgaaaca cttcggtctg atttattagt
     6961 caatgaaaga aggaaaaaat cagtatggaa gcagagacac cttttcaaaa agtagaaaca
     7021 ttccacaaaa cttttgatcc aagaagacca gagataccca cggcttttac agaaaatgaa
     7081 gctcatacac gtgctgcgtt caaaatagaa gaacttgttg aatttgttgc agctacttca
     7141 cctaataaag aacaactgca tgaagctgtt atgctgctgc acgaagcatt agataaagca
     7201 gaagaaaaaa tacttggtaa aacacagtgg ggaagtgatc cgctggttga acaagtagat
     7261 gcactgacag atatccttta ctttacttat ggttcttttt cattactagg aatagtgcct
     7321 gatcgaatat tcgaaatcgt ccatcaggca aatatgggga aattatttcc agatggaaaa
     7381 cctcattatg accctgtaac aaataaagtg ttgaaacctg aaaactggca gatggaatat
     7441 gctccagaac ctaaaatcgc ggcagaaatc caacgtcaga ttcaagaagc gattgctaag
     7501 aagaaatccg ctgatatagg catgtgcaca aatgaaaaag agtgatcaga gtttcactat
     7561 ttttgttatc tttatacgat ggaaaaacaa aagattttcg tttaagttag tgaatgcatg
     7621 aaaatagtat gctataatct agaatagatg tcttttgcac gagagacgta ttatttggat
     7681 ttatgccaag cagaacgcca tctgttgcat aaaagatgca tactgaaaac ggaggaacca
     7741 taaatgggaa ataatgttat catcggaatc gtcattgcaa tcattatagt cgccattgtc
     7801 gtctttttgg ttagttactt gatgaagaaa aaaaaccaag atcgattgga tgccttagaa
     7861 aaacgcaagg aagaattatt tgacttgcca gtgattgaag aagtcgatga tgttaaaaaa
     7921 atgcatctgg ttgggcaaag ccaaaatacc tttcgtgaat ggagtcaaaa atggaatgac
     7981 atatctactt cctcgttcgc tgaactagaa agtcaaattt tcgaagtgga aaacctcaat
     8041 gaaagttttc ggttcttaaa aggaaaaaaa gcagttgttg aagcagaagc tacaatggac
     8101 caaatggaga aacaagtgac ggaaatccgt gaaggtctaa aggaattgcg ggaaacggaa
     8161 gaacgcaact cactagctgt tcagcaggca cttgacgtct atgaagaact gaaagaaaaa
     8221 gtcagagaag acgagcatga atacggacca gctctttttg aattgcaaaa acagatcaaa
     8281 gtgatcgaaa aagaatttac gcagtttgtg actttaaaca cttctggaga ccctgttgaa
     8341 gcccgcgagg ttttggataa agcagaaaaa catacgtatg aagtggaagc tctgatgaaa
     8401 aaaattccac cgctgtatga ggagctccat accactttcc ctgaacaact tgaagaaatc
     8461 agtgatactt acgagaaatt gatggaagaa caatatgtat tcccagaaga agatcttgct
     8521 gaagatatcg caaaagtaag tcgaagaatt gaaaattcat tagccaatct tgaaaaaaca
     8581 gaagttgaaa cggtcgaatt tgaaaaccgt gaaacagctg atttgattga ttcgttatat
     8641 gatatcttag aacgggaaat ggaagctcag agatatgtaa aaactaacca atcaacgatt
     8701 gcagagtata tcaaacatac aacaaagaat aaccgtcaat tattgattga gctggatcac
     8761 acatctcaaa gctatacatt gaaccacaat gaaattggcc gtgtacgagg tttccaaacc
     8821 gaagtggaag aaatggaacg tcaaaatgaa cagatgattc cacagatccg tcaacacgaa
     8881 attccttatt cagaagtgcg cacgttctat aaaacagtct tcaaagtctt agaagatatc
     8941 gaaaagcaac aagtagagat cgacgactca ttacatgaat tgagaaaagg cgaaaaagaa
     9001 gcgcaagaaa agatcgatac attcgaattc aaattgcgca gtttgaaacg ttttgtagaa
     9061 aaacaacgtt tgcctggctt gccgaatgat tacctagaat tcttttttgt tgctactgac
     9121 cgtattgaag aactaagtgt tgtcttgaat aaaattcgag taaacatgga agaggtcaat
     9181 cgtttagttg ctctatgtga agaagatcta gaattattag ataagaagac acatgattta
     9241 gtagatgcag cagcattaac ggagcaaatg ctccaatatg caaatcgtta tcgtcataca
     9301 cacgaagaag tgagagaagc aattgataaa agctactatt tattcaataa agaatatcac
     9361 tatcaagaag cattagacga aatcggtaca gcattagagc gagtagaacc tggtgctttc
     9421 aaacgcatcg aagattttta ttttaatcat ccagacttag tataaagcaa aaaagttagt
     9481 aaaccagcaa gagcaagacg gattattgtc ttgttcttgt ctttttttgt atatttgaaa
     9541 attgaaacaa gtgaaaattt cacctgctct tgaaagcacc ttggacaacc gttataatag
     9601 aaaagaattt caaaaaagag gggtttctta tgatatattt tgataacagt gcaacaaccc
     9661 caatctttcc gcaaagctta gatgcatatg taaaaaccag tcagcggatt attgggaatc
     9721 catcaagctt gcatgattta ggcaatcaag ctaaccggtt gttgcagcaa gcaagaaagc
     9781 agatcgctga tttgatccat gtagaaccag aagaaatcta ttttacttca ggcggaacag
     9841 aaggagataa ctgggtatta aaaggaacga tgatcgaaaa aagagaatat gggaatcata
     9901 tgatcatttc aggagtcgaa catccggccg tcagcgagac agcagaacaa ttaaaagaat
     9961 taggaatcga agtaagtatc gccccagtgg ataaacgcgg atttgtacgt gtcgacgaat
    10021 tgaaagaatt aataagaaaa gagacagtat tagtctctgt tatggctgtg aataatgaag
    10081 taggatcgat tcagcccatc caggaaatca gtgatctttt ggatgatttt cctaaaattc
    10141 atttccatgt agatgctgtt caggcgattg gaaaagtacc attctcgcaa tggttgacag
    10201 aaagagttga ttttgcaaca ttttcagctc ataaattcca tggcccacgg ggaactggtt
    10261 tcatttattg gaaaaagggt cgtcgtttag caccattact gacaggtgga gggcaagaaa
    10321 gaaatcagcg aagtgggaca gaaaatgttc caggtattgt ggctatggtt aaagctttac
    10381 gtttatcatt agagataaag gaacaaaaac ctgagcagac acaacgctta aaagtagctc
    10441 taatcaatgc gttgaagacg tatgagaaag tgacgatttt ttcagaagga actgactatg
    10501 caccgcatat tttatgtttt gctctaaaag gaattcgcgg cgaagttctc gtccatgcct
    10561 tagaagaaaa acaaatattt gtttctacta ctagtgcctg ctcctcacgt aaacatatgg
    10621 caagcagtac attgcacgca atgcatgtac caaatgatct ggctacatct gctgttcgaa
    10681 tcagcttaga tgaaaacaat tcgcttgcag aagtcgagca atttatgatt attttcaagc
    10741 agctttataa gaaattttct gcaatcaatt aaaagaggag tgttcttgtg aaatacagtg
    10801 aaattatggt ccgttatggg gaactttcga caaaaggaaa gaatcgaaaa agctttatca
    10861 tgcaactagc acaaaatgtc agacaagctt tgaaagactt tccagaaatc aaaatccatg
    10921 ctgatcggga ccggatgcat cttttattga atggcgcaga cgggcagcta gttattccaa
    10981 aactagcaaa aatatttggg atccaaaatt tctctccaag tattcgtgta gaaaaagatg
    11041 tcgaagtttt gaaacaagct gttcaagaca tcatgaaaga aatttatact gggaaagaaa
    11101 catttaaaat tatcgctaaa agaagcgatc accaatttga attgacaagt aatgaattga
    11161 atcaaacatt aggtaatgct gtttttgata ttttcccgca tatccaagtt caaatgcgtc
    11221 aaccagatat tccattacgt gtagagattc ggcgtgatgg cgcttatcta tcgtatgaaa
    11281 cgatcaaggg agctggagga ttgcccgtag gaacaagcgg aaaaggaatg cttatgcttt
    11341 ctggggggat tgattctcct gtagcagggt actttgccat gaagcgggga gtggaaattg
    11401 aagctgttca ttttgctagt ccgccgtata caagtgaaca agcactgcaa aaagcaaaag
    11461 atctaacagc caaactagca ccttatgtgg gaacgatcca ttttatcgaa gtgccattta
    11521 ccgagattca agaagaaatc aaaaagtcag tgccacaagg atattggatg acaattactc
    11581 gtcgaatgat gttgcgtttg accgatgaaa ttcgccgtat tcgtcatggt ttagtcattt
    11641 tgaatggtga atcattaggt caagtggctt cacaaacttt gcaaagtatg gtggctatca
    11701 atgaagtaac gaatacgcca atcattcggc ctgtagcgac aatggataaa cttgaaatca
    11761 ttgaagtagc agaacagatc gatacattta atctttctat ccagcctttt gaagattgct
    11821 gtacgatttt tgctcctcca cagccaaaaa cacgccctca actggaaaag gtccatcaat
    11881 atgaagagcg tttagcaata gatgaaatga tccaacgagc actagctggc ttgaagatgg
    11941 aagagataca agcagaatcg tctaatgaaa aaactgaaga attttcagaa ttgctataag
    12001 aggttatgaa aatagtgttt tgaccagagt attagagaaa caaaacgaaa aaatagctcc
    12061 atgtatttta ccgtttttga actaatgtcg aagattagct gattgaatac catttatcaa
    12121 gaagttatgg aaaagccggt tcttttttac taactgaaaa ataaaatttt atttagagat
    12181 caagctacag ttgataaatg atataaaaaa gagaatttcc catgaaatag cgaggttgtg
    12241 acagaagtgg gcagcttcaa gaaataagaa ggaatttacg aaaattgctt ttcaaatttt
    12301 tgtgaaattt cggcttattt ttcgaagaag ttacttctgg aacaccgtgt atcagaggtt
    12361 g
//
LOCUS       DAZAOD010000078        12135 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000078 DAZAOD010000000
VERSION     DAZAOD010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.080"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..610
                     /locus_tag="ACHDPO_002137"
     CDS             <1..610
                     /locus_tag="ACHDPO_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFN3369750.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="ACHDPO_002138"
     CDS             723..1001
                     /locus_tag="ACHDPO_002138"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3369751.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="ACHDPO_002139"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="ACHDPO_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFN3369752.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1458..2213
                     /locus_tag="ACHDPO_002140"
     CDS             1458..2213
                     /locus_tag="ACHDPO_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFN3369753.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="ACHDPO_002141"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="ACHDPO_002141"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFN3369754.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="ACHDPO_002142"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="ACHDPO_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFN3369755.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="ACHDPO_002143"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="ACHDPO_002143"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFN3369756.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="ACHDPO_002144"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="ACHDPO_002144"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFN3369757.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="ACHDPO_002145"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="ACHDPO_002145"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFN3369758.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="ACHDPO_002146"
     CDS             6950..7492
                     /locus_tag="ACHDPO_002146"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFN3369759.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /gene="atpA"
                     /locus_tag="ACHDPO_002147"
     CDS             7515..9071
                     /gene="atpA"
                     /locus_tag="ACHDPO_002147"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFN3369760.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="ACHDPO_002148"
     CDS             9085..9987
                     /locus_tag="ACHDPO_002148"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFN3369761.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="ACHDPO_002149"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="ACHDPO_002149"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFN3369762.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="ACHDPO_002150"
     CDS             11430..11852
                     /locus_tag="ACHDPO_002150"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFN3369763.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4035 a         2155 c         2677 g         3268 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttatt
//
LOCUS       DAZAOD010000079        12069 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000079 DAZAOD010000000
VERSION     DAZAOD010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.081"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(22..579)
                     /gene="frr"
                     /locus_tag="ACHDPO_002151"
     CDS             complement(22..579)
                     /gene="frr"
                     /locus_tag="ACHDPO_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFN3369764.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(582..1304)
                     /gene="pyrH"
                     /locus_tag="ACHDPO_002152"
     CDS             complement(582..1304)
                     /gene="pyrH"
                     /locus_tag="ACHDPO_002152"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFN3369765.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1440..2321)
                     /gene="tsf"
                     /locus_tag="ACHDPO_002153"
     CDS             complement(1440..2321)
                     /gene="tsf"
                     /locus_tag="ACHDPO_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFN3369766.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIEYDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2420..3202)
                     /gene="rpsB"
                     /locus_tag="ACHDPO_002154"
     CDS             complement(2420..3202)
                     /gene="rpsB"
                     /locus_tag="ACHDPO_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFN3369767.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3561..4040
                     /locus_tag="ACHDPO_002155"
     CDS             3561..4040
                     /locus_tag="ACHDPO_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFN3369768.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4257..5348
                     /gene="phnW"
                     /locus_tag="ACHDPO_002156"
                     /pseudo
     CDS             4257..5348
                     /gene="phnW"
                     /locus_tag="ACHDPO_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
     gene            5341..6126
                     /gene="phnX"
                     /locus_tag="ACHDPO_002157"
     CDS             5341..6126
                     /gene="phnX"
                     /locus_tag="ACHDPO_002157"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFN3369769.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(6472..8163)
                     /gene="argS"
                     /locus_tag="ACHDPO_002158"
     CDS             complement(6472..8163)
                     /gene="argS"
                     /locus_tag="ACHDPO_002158"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFN3369770.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8585..9532)
                     /gene="arcC"
                     /locus_tag="ACHDPO_002159"
     CDS             complement(8585..9532)
                     /gene="arcC"
                     /locus_tag="ACHDPO_002159"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFN3369771.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9647..10666)
                     /gene="argF"
                     /locus_tag="ACHDPO_002160"
     CDS             complement(9647..10666)
                     /gene="argF"
                     /locus_tag="ACHDPO_002160"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFN3369772.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10757..11986)
                     /gene="arcA"
                     /locus_tag="ACHDPO_002161"
     CDS             complement(10757..11986)
                     /gene="arcA"
                     /locus_tag="ACHDPO_002161"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFN3369773.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3296 a         2521 c         2175 g         4077 t
ORIGIN      
        1 ccctctgttt ttatgatttt attaaacttc caataattct ttttctttat cagcagcgat
       61 cttatctact tctttaatgc tgttatctgt caatgtttgt acgtcttttt ctaatccgcg
      121 caaatcatct tcggtaatat caccattttt ttgttgtttt ttatattcat cgatcgcatc
      181 acgacggatg ttacgaatcg cgatttttgc attttctgct tcttttttca catctttagc
      241 taattctttt ctgcgttctt ctgtcagttg cgggataact aagcgaatga catttccatc
      301 attggttgga ctgattccga tatcacttgc cataatagct ttttcaacat cttgaagaat
      361 gctcttgtca aaaggtgtga tcattaaaac acgtgcttct ggaatttgga ttgatgccat
      421 ttggttcaat ggtgttggcg caccgtagta gttcacagta atacggtcca aaaggctagc
      481 gttcgcacgg cctgcgcgga tttgcccaag ttcacgttga agattttgtg ctgctttttt
      541 cattttttct tttgcttctg tcataattgc atctgccatt tttatttccc ccttacagtt
      601 gttccgatat tttcgcctaa gattgcacgg cgaatatttc cgtgttcatt taaattgaag
      661 acaagcagtg gaatatcatt atccatgctt agtgaacttg cagttgaatc catgacttgt
      721 aatcctttgg caataacttc cagatgagtc agttcttcaa attttactgc atttgcatct
      781 actttcggat cagcagaata aacaccgtct acattgtttt tagccatcag gataacatct
      841 gcgccgattt ctgccgctcg taatgctgct gttgtgtctg tcgagaagta cgggttgccg
      901 gtaccgcctg caaagataac gatccgtcct ttttctaaat gacgttctgc tttacggcga
      961 atatatggct ctgcgatttg acgcatttca atcgaagttt gcacgcgtgt cggtacaccc
     1021 acgttttcca acgtatcctg taaagctaag gcattcataa ctgtagctaa catacccatg
     1081 taatcagctt gagcacgttc catgcccatt tgtgctccga tttgtccgcg ccagatattt
     1141 ccgccaccca caacgattgc catttcaacg cccagctcgt gaacttcttt gatttcttgg
     1201 atgatttctt tgattactgg tggtttgatt ccaaatcctg catccccagc taaagcttct
     1261 ccactcaatt ttaagactac acgctgatat ttcggtgtga ccatgttcat tcctccaata
     1321 ttttctattg ccattttacc atacttagat gatttcgaca ctctaagact ggtttttctt
     1381 gttttgctta aaaaaaggga gcgcacaaac cgtgcgttcc cgtctgttat tcaacagaat
     1441 tattttttca cttggctcat aacttcttct acaaagttat cttcgcgttt ttcgatacct
     1501 tcgccaactt cgaaacgtac gaatgtttta acagttgcgc cttttgatgc aacgtatttt
     1561 tcaacagtca tatcaggatc tttaacgaat ggttggtcca ccaaagcgat ttctgctttg
     1621 aatttcttca agcgtccttc taccattttt tcaacgatat tcgctggttt gccttcgttc
     1681 aatgcttgtt ctgtaagaac agttttttca tgttctaatt cagcttctgg aatttgtgat
     1741 tcgtttacat aacgaggatt gatagctgct acgtgcatag ctacgtctct tgcaactgtt
     1801 tcgtcagttg ttccatctag aacagtcaat acggcaatac gtccgcccat atgcaagtat
     1861 ccaccaaatg cagcattgtc gtctttttct acaacttcaa agcgacggaa gctgattttt
     1921 tctccgataa cttgagttgc ttcgatcaag tcatattcaa ttgtaccttt atctgttttg
     1981 attttcattg cagcttccat gtctgctggt ttgttttcag caacaagttc tgcaatttct
     2041 tttactaaat cttggaacat ttcgttttta gaaacaaagt ctgtttctga gtttacttca
     2101 acgattgctg cagtgttacc tttcacagca actgaagcca atccttcagc tgcaatgcgg
     2161 tcatttttct tcgcagcctt tgccattcct ttttcacgta aaagatcaac tgctttttcc
     2221 atgtcgcctt ctacttcaac taatgctttt ttcgcatcca tcattcctac gccagtcatt
     2281 tcgcgtagtt cttttaccat tttagctgta acgtctgcca tgtttaactc ctcctgtgtg
     2341 tttttctttt taaaaaaagc tgcttcaaag gagagtgagg cttgtcgccc agcctttgaa
     2401 acagctccat cattcaaaat tattctgctg aagaattgtc gccttcaaca acatctacga
     2461 tttcttcgat tgatgttgct gtgttttctt ctgtgaaatc ttcttcaact acttgatctt
     2521 caccttggtt tccttcgatg aaagcatcag ccatttttga agtaatcaat ttaacggcac
     2581 gaattgcatc gtcgtttgaa gggattacta cgtcgatttc atctggatcg cagtttgtat
     2641 caaccatagc tacgattggg atatttaatt tgtgtgcttc ttgaacagca atacgttctt
     2701 tacgtgggtc aacgatgtac attacatctg ggattcttgg catatcagcg ataccgccta
     2761 agaatttttc aagacgttca cgttctttgt tcaaaccagc aacttctttt ttaggtagaa
     2821 cttcaaaagt tccatcttct tccattgcat tgatttgttt caaacggctg atacgttttt
     2881 ggatagtatc ccagtttgtc aatgttccgc ctaaccaacg atggttaacg aagtattgtc
     2941 ctgcacgagt tgcttcttct ttgattgctt cttgtgcttg tttttttgta cctacgaata
     3001 atgctacgcc gccttcttca gcaacgctct tcatgtaatc ataagctgca tctactaatt
     3061 taactgtttt ttgcaagtca atgatgtaga ttccgtttct ttctgtgaag atatatttct
     3121 tcatttttgg attccagcga cgagtttggt gaccaaagtg tacgccggct tctagtaatt
     3181 gtttcataga aattactgcc atgtttgttt cctccgattt ggttttattt ttcctcttct
     3241 tatcttctac cttgccggca aactttttca agcacctacc gacaatccaa taagaatgtg
     3301 gatttgctga tgcataaagc accctcagct attatacaga caaaagatcc gtatcgcaag
     3361 agcaaatata cttttctgct caacattcaa tagtttacct gaaagataaa aagaattcaa
     3421 gaaaaacagt agatttctct ttgtttcttt attatccttt ttccataaaa taattttagg
     3481 tataaaagac gaatattatt gggcaatcct tctttttttt gttatgatac atgtgaaatc
     3541 tttcgtaaag gagaaagaaa atgcgcaaag ctcaaagaca tttgctgatt aaacaagtca
     3601 ttgaagaatt cccgatccgt acgcaagaag aactattaaa caaacttggg cattatggcg
     3661 ttaccgccac gcaggcaacg atttctcgag atatccgtga tctaaaaatc gtgaaggcac
     3721 ctgatgaaaa tggcgtttcc cgcttcgtat tgtttcgcga aaaaggaact cctgagacta
     3781 ggactgagga agaggatcgg ctggttcaaa tgattgaaga cattgtattg aaagtcgaac
     3841 gagtccactt tttgacgatc gtcaatacct tgccagacaa tgctcattta tttgcatctg
     3901 ttttagatga gatcaaacct ccctctattg tcagtacaat tgctggattc gatacgatca
     3961 tggtcatctc ggaaaatgag gaggacgcaa aacgagtaga agaatttctt caccatccaa
     4021 ctgaagtatc acttttttaa tcagagcacg tattcctaat atggaatgcg tgttttttta
     4081 ttttcaatat tttccttatt aaataaacct ttacactctt tacaaaaata catcattttt
     4141 tattcaattt tttcaacacc ttgattgaat cacaataatc atcatttata ttggatgtta
     4201 acaagagcag cttcttgctc tttgtgtatt tcaaaaaaga aatgaaagga aatcatatgt
     4261 ataaattatt aactcctgga ccattgacga cttctgaaac agtgaaaaat gctatgctga
     4321 tcgatcattg tacttgggat caagaataca aagaaattac acaatggata agaaaaaaat
     4381 tattggatct tgctcaagta tcggaaggaa tatacacaac ggtcttaatg caaggtagcg
     4441 gctcctttgg ggtagaatcg gtattaagtt ctgtgatcag gccagaagat actgtactga
     4501 tttgttcaaa cggcgcatat ggacaacgaa tgatcaacat gtgcgaatgt ctgaaactga
     4561 actataccgt ttatgaggta tcgtaacatc aaatcctcca agctcatgtg attacacagc
     4621 tgattgaaga gaatccctct atctccgcac tagcaatggt ccatagcgag actacttccg
     4681 gtattttgaa taatttggaa gagattgctg ctgtcacaca agaaaaagat cttttgttta
     4741 tagtggacgc gatgtcaagc tttggtggga taccgattcg tgtagccgaa ctagggattg
     4801 attttttgat ttccagctca aacaaatgta ttcaaggtgt tccaggcttt tcttttgtac
     4861 ttgctaataa agcggaacta gaaaagcgaa aaaatgtgag tcgaagtttg tcacttgatc
     4921 tatatgacca gtaccgcgtg atggaaaacg agaatggcaa atggcgtttc acttccccta
     4981 cccatacggt tttggctttt caacaagcgc tgaaggaact agaggcagaa ggaggaatcg
     5041 aaactcgata ttcacgttat ctcgccaata atcatgtact acgacaaaaa atgacagaga
     5101 tggggttcca gcctttcatt caagaatatc aggggccatt catcacctct tttctttacc
     5161 ctaaggactg gcgatttgat tttaatcatt tttatcagta tttaaagcaa aacggatttg
     5221 tgatctatcc cgggaaaatc agcgatcatg aatgttttcg tatcggaaat attggcgaga
     5281 tctatccgga agatattttg gaactgacag caattatcaa agactataag gagaacgtta
     5341 atgattaaaa ctgtaatttt tgattgggca ggaacaactg tggactttgg ctgtatggct
     5401 cctgtccacg cttttagaaa tgcttttcta gaaaaaggaa tccaactgac tgacaaagaa
     5461 atccgcgaac cgatgggaaa attaaaatgg gatcatatcc aacagcttct ttccctccct
     5521 tctgtcaaaa aacaatggat agctatttat ggacaactac ctcaggaaaa agaggtggag
     5581 gaattgtatc aacaatttga acattatctg tttaaagatt tggtcaagca ttctaccttg
     5641 aaacccgaca cattggaaac gatcgaacgg ttgagaaacg ctgggatcaa tattggttcc
     5701 acgactggat ttactgctcc tatgatgaca atcgtagcag aaaccgcaaa aaaagaaggg
     5761 tattcaccag acttcatggc aacttctgaa gacgtcgaag ggtatggtcg accgtttcct
     5821 tatatgatcc ataaaaacat gcagtacttc aaaaacaagt cggttgatga agtaatcaaa
     5881 gtcggagata cggtctcaga tatccaggaa gggaaaaatg ccggagtgtt gacagtaggt
     5941 gtaattgaag gtagttcgct aatggggatt tcttatgatg agtaccaaaa attagagatg
     6001 gggaaaaaag atcgtttaaa acagtctgtt gctcttagat tccaacaagc tggcgctgat
     6061 atttgtgtaa acaatttaaa agagttaaca gaatacattt tgtacgctga caagaatcca
     6121 gaatgacttt tatacaaaat cagaggtcgt gaaaaagctg tactgcatca agtaataaga
     6181 acagccaaac aaaaatagct cctcatattt ttcgtttggt taggcttatt accgcagatg
     6241 caagcttttg aacaccgttt attcgaaaaa aaaagggagc tgtgacacga cttttgtcac
     6301 agtcccctta tttacaaaca aacagtgttt aagagacaac ctctccacta aacggtgttc
     6361 attcagctga ctctcggtat ttgctcaaaa aacgataaaa tttgaaaagc tattttctct
     6421 tttgtttctc taatactcgg atcagaacgc tgatttcaca ttctcttttt cttacatctt
     6481 atctggtgca tgaagtccta gcaaacgaag gtcttctttc aataatacag tcactgcata
     6541 aactagagct aagcgtgctt ctttttgttc atcatcagct aaaatcttcg tatgagcata
     6601 gtatttgttg aatgcttgtg ctaatttgat tgcatgtttc gcaatcactg acggttcgta
     6661 tttttcccca gcagacaaga ccgtttcagg gtatttttga actaatttaa ccacttccca
     6721 gctggtatcg tcattcaatg catagtctgc tgtttctgaa gggacaaatc ctgctttttc
     6781 caacaggctg actgcacgag catgtgtata ttgcacataa ggtccagttt ctccttcaaa
     6841 tcgaacaact tcttccaggt taaagtcaaa tgtattcagt cgatcgtttt tcaaatcgtg
     6901 gaaaatgact gccccaaccc caacttgttt agctacagca tctttgtttt ccaaatcagg
     6961 gtttttctcg ctgatttgtt ctttagcaga ttggattgct tcatttaata cttcttctaa
     7021 taagacgatc tttcctttac gagttgataa ttttttacca ccttgcgtga tcaaaccaaa
     7081 tggaatatgg cgcatatcgt cagaccagtc aaagcccatt tccttcaaga cagctttcaa
     7141 ctgtttaaaa tgatagcttt gttcattccc tactacatat agagattgtt tgaagtcgta
     7201 agtacgttta cggtacaatg cagcagctaa gtcacgtgta atgtatagtg tcgcaccgtc
     7261 tgacttctta atcaacgctg gattcaggtc ataagcagat aggtcaacga tctctgcacc
     7321 tttatcctcg ttcagcaaat gtttttcttc taaaagtttg acgatttcat ccatcttgtc
     7381 attgtagaaa gcttcaccgt tcaacgaatc gaaacgtact tccagcagat catagatttt
     7441 attgaattct ttcatcgatt catcacggaa ccattgccat aattgaatag cctcttcatc
     7501 gccttcttcc agacgtttga accaagcacg agcttcttca tttaattctg gttctgtttc
     7561 agctacttca tggaattgga catataaacg aagcaattca ttgattggtt ctgctttaac
     7621 agcttcttct gtaccccatt ttttgtaagc gacgatcagt tttccaaact gtgttcccca
     7681 gtcacctaaa tggttgatgc ggattggctg ataaccgatt ttttccataa tgaaaccgat
     7741 cgaattaccg ataactgtcg aacgcaaatg tcccattgag attggtttgg caatattagg
     7801 agaagacatg tcgattggta ctgttccttg attcccgata ttgctatccc cataatgttc
     7861 tttttctttc actactgttt gcaaaacttt tttgctgata agttctttat tcatgaaaaa
     7921 gttcaagtaa ggtccgacaa cttcgatttt ttcaaagttg gcagaatcga ttttttctgc
     7981 taaatctgca gcgatttgct gtggcgcttt tcggtaaact tttgctaatg aaaaggctgg
     8041 aaatgcaaca tctccgtgtt cagctgattt tggattttct agtaattgtt cgacttgttc
     8101 cagtgttaaa tcatctttga cagcgtcata gacagctttt gcgacaagat ctttattatt
     8161 catctttatt cctcctaaag tgctcccttg attgttaaac aaaaaaaatc tctagcgacg
     8221 gcatacttag tatgccatca ctagagacga gatttcccgc ggtaccactc caattgtcct
     8281 aaaaaaggac cagctccatc tgatatcggt agacgaccgt ctgtttaaaa cagaattctc
     8341 caagtgcgct tcgttgtatc ttcttcattc ggcttccacc acttccgaat tcgctagcca
     8401 agaatgatac aagtactctc ttgttcaaca aatcttagtc ttattaaact ttcttgaatt
     8461 atatcagaaa aaaaaacgaa aggctagtcg tttctgataa aaaaacaatc cagatggcct
     8521 aaaggagaag aaataccacc tggatagcta taaatcattt cgtaaatacg aaagacttaa
     8581 caaattaatc agctacgata atcgttcctt cttcagaagc taaaagattc tcgatatttt
     8641 ctaaagaagt gatgattgcc ttagcgtttg gttttgcttc aacaaatgca atagctgcct
     8701 ctactttcgg aagcatgctt cctggagcaa attgcttttc atcaatgtat tgtttcattt
     8761 ctgaaacagt aacagtttct aatttctttt gatctggttt ttggtaattg acatacacat
     8821 tgtctactcc tgtcaatacg atcagcaaat ccgcatcgat gatttcggct aatttttctg
     8881 aagcaaaatc tttatcgatt acggcttctc gtccttctaa tccagtagct gtttctacaa
     8941 caggaatccc accgccacca acagagactg tgataactcc ttgatcgacc agcgtttcga
     9001 tgacacgtgc ttctttaatc gagatgggtt taggggaagc gactactttt ctccatccac
     9061 gtccagcatc ttctttgaat gtcacagtgg agtcagcatt catttgttct ttggcttctt
     9121 cttccgtgta gaatggaccg actggtttac ttggattttt gaatgaagga tcattttcat
     9181 ccacaataac ttgagtgact aaagaaacca catctttatc gatccctttt tccttcagta
     9241 cttcgcccat ggcattttgt aaccagtaac cgatagatcc ttctgtcatt gcaacacatg
     9301 tatctaaagg cattgccggt gttttctcag aatcagcagc ttgctgctga atcaataggt
     9361 taccgacttg cggaccattt ccgtgggaga tgatcaattc atctccttgt tcgataaatt
     9421 tcactaaata ctttgctgtt tccattaacg cttcttgttg ggcttttgca cttgcatccg
     9481 tagacaagat tgcattaccc cctaaagcga caactacttt tcgtttggcc atttcattcg
     9541 tcctttcttc agttctaccg aattttctag ataacaaaac gagccagcgt tttgtgattt
     9601 tccctcaatg ctgactcgtt ttttcgtgag atgaatgtgg ttatgcttaa acgcgaggga
     9661 taaacaagtt acctaatgtt gctgccatga tcgctttgat tgagtgcata cgattttctg
     9721 cttggtcaaa ttgacgagca tatttgctgc ggaagacttc atctgttact tccatttcag
     9781 tgatgccaaa gcgttctttc atttgttcac cgtaaacagt gtttgtatca tggaaagctg
     9841 gcaagcagtg caagaagatc aaacgatctg tgttgtgtgt tttttctacc atttccatat
     9901 tgatttggta aggtttcaac aatttgatac gttcttcgaa tttatcttct tcacccattg
     9961 atacccatac atcagaataa aggacgtctg ctccgtctac acctttatca acatcgtcgg
    10021 taatcatcaa ttgtgcaccg gatttttcag caaagccttc tgccattttg acgatttctt
    10081 cttcaggttg taattctttt ggtgcaacga tacgcatatt cgctcctaaa attgcacctg
    10141 tgactaataa agagttagcc atattgtttc gaccatctcc gcagtaagca acagtgatac
    10201 cttctactgt tccaaagttt tcttggatag ttaaaaagtc agcgatcatt tgtgttggat
    10261 gccattcatc agtcaagcca ttccaaactg gaacaccaga gaattctgct agttcctcta
    10321 ccattttttg actgaatcca cggaattcga ttccatcaaa catacgacct agtactttag
    10381 ctgtatcttc tgtggattct tttttaccta attggatatc atttgcacct agatattcag
    10441 gatgtgcacc tagatcgatc gctgcagtag taaatgcaga acgagtacgt gtagatgttt
    10501 tttcaaataa aagcgcaata ttttttcctt ctagatagtg atgtgggata ccacgttttt
    10561 tcaagtcttt caagtgttct gaaaaatcga tcaaatattg taattcttct tttgtaaagt
    10621 ctttttctgc taataagctt cttccttgga atactgattc tttcatatta aacattctcc
    10681 tttagattgt ttttatttaa gattaaagag gaaatcccga cggcagctga cagtaagacc
    10741 gccgtcagga aacaaattac ttcaagtctt cacggacaag tggttggctc atgcagcgtg
    10801 gaccaccacg gcctcgtgac aattcacttg aattgatttc taacactttg atgccatagc
    10861 tacgaagcaa ttcgttcgat acataatttc ggttataagt gactacaaca cctggagcga
    10921 ttgccaatgt gtttgatcca tcattccatt gttctcgagg tgcaacgatc tcatctccat
    10981 taccagttgg gatcagtaca agatcatcta atccaagagc agctttcatc gtttcgtgta
    11041 agttatctga atgagtaatc ttgatatcat caccatctgg ttcgattgta aagacatcca
    11101 tcttaccgtc tttactttga attgctggat ggatagtgaa tttatcgtga tctaccattg
    11161 taaatacggt atccaaatgc atcattgcac ggttgtttgg aattttgatt gctaacactt
    11221 tttcaaatcc tgaatttttt gcgaataggt ggcgtgctaa tttttctaaa gctttcgcat
    11281 tagttcgttg agaaatccca acagctacta ctttatcgct taagatcaat tcgtctccgc
    11341 cttcgatatg atctggattt tcacgatcca accatacttc gattccttta tttgcaaatc
    11401 ttggatgatg tttcaaaata tattctgtaa acatcgattc acgacgacgt gcttcaaaag
    11461 tcatcttatt gactgtcatc ccatttccca ttgatgcgga agggtcgcgt gtaaagtaca
    11521 agtttggcat tgggtccatg taaaatggat agtcatcgtc tgctgacaga tcgtatagac
    11581 tgctagaacg tacttcaata tcttttgtac gaaccccagc catgatttta tctaccattt
    11641 cttgcgtttc cattgataga aggaactcat gaagaccctc tcttacagca ttcgatgcaa
    11701 tatgagattc atccaacatt ttattcaaga attgttcttt gacattgcct gcgtcaatcg
    11761 cttctgccgc taatttttcc aagtaaagag tctcgacgcc ttcattttgc aatgtctttg
    11821 caaagttgtc atgttcttct tgagcaatcg gaagatatgg aatatcatcg aacaacagac
    11881 gatccataat atctggtgtc aaattttcca cttcttgtcc aggccttttc agtaaaactg
    11941 tctttaattt ccctatttca gagaaaacgt gaataggttt atccatgttg tgttgcctcc
    12001 ttctttttga ttacatgtat aggatatcct ccttttgtaa tcactttcat aattttgtct
    12061 cattcaaaa
//
LOCUS       DAZAOD010000080        11908 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000080 DAZAOD010000000
VERSION     DAZAOD010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.082"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..465
                     /locus_tag="ACHDPO_002162"
     CDS             <1..465
                     /locus_tag="ACHDPO_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFN3369774.1"
                     /translation="WKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAF
                     LKRLVKQFDEPKVVVTDKAPSIASAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVK
                     RRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPD"
     gene            complement(1080..2120)
                     /locus_tag="ACHDPO_002163"
     CDS             complement(1080..2120)
                     /locus_tag="ACHDPO_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFN3369775.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(2469..2795)
                     /locus_tag="ACHDPO_002164"
     CDS             complement(2469..2795)
                     /locus_tag="ACHDPO_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369776.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2782..3570)
                     /locus_tag="ACHDPO_002165"
     CDS             complement(2782..3570)
                     /locus_tag="ACHDPO_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3369777.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3938..4228)
                     /locus_tag="ACHDPO_002166"
     CDS             complement(3938..4228)
                     /locus_tag="ACHDPO_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFN3369778.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(4364..4543)
                     /locus_tag="ACHDPO_002167"
     CDS             complement(4364..4543)
                     /locus_tag="ACHDPO_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369779.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4540..4890)
                     /locus_tag="ACHDPO_002168"
     CDS             complement(4540..4890)
                     /locus_tag="ACHDPO_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369780.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4883..6208)
                     /locus_tag="ACHDPO_002169"
     CDS             complement(4883..6208)
                     /locus_tag="ACHDPO_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFN3369781.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6658..7272
                     /locus_tag="ACHDPO_002170"
     CDS             6658..7272
                     /locus_tag="ACHDPO_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3369782.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(7437..7679)
                     /locus_tag="ACHDPO_002171"
                     /pseudo
     CDS             complement(7437..7679)
                     /locus_tag="ACHDPO_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7883..9202)
                     /locus_tag="ACHDPO_002172"
     CDS             complement(7883..9202)
                     /locus_tag="ACHDPO_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFN3369783.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(9336..9944)
                     /locus_tag="ACHDPO_002173"
     CDS             complement(9336..9944)
                     /locus_tag="ACHDPO_002173"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369784.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSLNNSYF"
     gene            complement(10582..10839)
                     /locus_tag="ACHDPO_002174"
     CDS             complement(10582..10839)
                     /locus_tag="ACHDPO_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFN3369785.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(10832..11101)
                     /locus_tag="ACHDPO_002175"
     CDS             complement(10832..11101)
                     /locus_tag="ACHDPO_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFN3369786.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(11232..11411)
                     /locus_tag="ACHDPO_002176"
     CDS             complement(11232..11411)
                     /locus_tag="ACHDPO_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369787.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            11509..11745
                     /locus_tag="ACHDPO_002177"
     CDS             11509..11745
                     /locus_tag="ACHDPO_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369788.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISF
                     FLLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
BASE COUNT         3675 a         2151 c         1826 g         4256 t
ORIGIN      
        1 tggaaaatgg atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc
       61 atcgatgcag atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca
      121 gcctatgctt ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca
      181 gataaagcac catcaattgc tagtgccttt aagaaactaa aagaatacgg attttatcaa
      241 gggacagaac atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca
      301 gtaaagagac gcaataaatt ctatcgaagt ttacgcactg cctcacccac gattaaaggc
      361 atggaagcca tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt
      421 tcggtctgta ctgaaatcaa ggtattattg ggaatcccag attaaatcat agataccgta
      481 agggatttta ttctttattt aaaactttgc aacagaaccg tccgttgcgg gtaataccgt
      541 aacactgaag ggcacgcatt aaggcgtcat cttaatgctt tcctgtagga cactgacgga
      601 gattaccagt ctcccgagcc ttacaggggc ctttcttttt ttgtattttc aattatcaca
      661 atttatcgtc caaaagtgca gaacgaaaat caattcatca caagcatatc agacaattaa
      721 atttaaaaca actaaaaata tacaaaaaag tgtaattgaa tattagcagc actgcctgaa
      781 aagaagtaat atcaggcttt tcagcttggg gaaataagtg aattacctct cttcatgaat
      841 tattataact caaaaaagca catatgcaaa cactagttcc ctattttttt gaatgaaaaa
      901 taactaaaat atctaacgat tatgacttta aaacctacgt ttgcgattgt tttcataaac
      961 ttttaatcta aaaactccgg aataatagct atttatttgt aacatttgta ataaaattaa
     1021 aatcataaaa aagttctaat ttaaaattga tcatttttat agtgatcgct ttttatcaac
     1081 tactctagcc aattttccgt actaactgtt ggtaattcgt taaatgtttc tctttgttcg
     1141 tttgcaagct ttgccgcaat agctttttcg acaaaccaat tttttacata aacgaaaatt
     1201 agattctgca aattgtttac tttttcagtt ttttgttttt gataagcttt cagcaaagtc
     1261 atatataatc ctttgtcagc atcaattcca taagattcca gttcttcata aacaacaact
     1321 gtttgctcta attcttcagc ttttttcttt gcattatgaa tagtttggac ggttttttga
     1381 gcgtcttcgt aagtactaga aaatgttttt atcaagttta atacattttc tggtacaaat
     1441 gtatttatac tgtcctcttt catgatgtcg acgaagttat ctagtaaaac ttgattttgt
     1501 aactgatcag tttcagtgtc tattatgtgt ctattagtgt ctatagaatt agaatagaat
     1561 agattgtctg cgattttcgc aattacggtt gagtccttga tatgactgga ttttgccgta
     1621 tttgcgattt tcgcaattac ggtggtatca ttgatttctc gcggttttgc cgtatttgcg
     1681 attttcgcaa ttacggtggt atcagtattg tcttcctctt ccatgatttt aaagacgtct
     1741 tgattcgtta cttctggctt gcctaagtac aataaattag gcatggattc aatcttaccg
     1801 tcacgtttat ttactcttcc tctcttctgt ttcagaagac ctgctttttc taattccttt
     1861 ttgattttag atactttacc ttcgcggcat tgtaacaatt tcattaattc ttcaactgtg
     1921 aatatgaaaa atatattatc atcagaatct acccagttat ttttgactga ataatcaaat
     1981 cgatctttaa gtagcatata agcaattttt gcatcatttg atagatccat gtatttttcg
     2041 ttagtaaaaa ataccttagg catttgataa tatttttcac gataaatttc ttttgatttg
     2101 taataattaa aatcattcat agccaatcct ctttctgtag gatagcgttt tgttcaaaac
     2161 tatgttacaa tgaattaaac aaatatatct atccactata tatttttcta ctgctgataa
     2221 gtcgccaaac tttgttaaag cagtagtctt tttttatctt tttttagttt accttaaaaa
     2281 ataaattaaa gcaaaccgct ctatttcaag gtttaagctc atagtaacta tatcacgata
     2341 ttacaataat attatatcac gatatcgtaa tattacaata tgaagataag cgacttatca
     2401 gctttgatac tactgatttt tataaaaaaa atatcacgat attatgatat cgtgatattg
     2461 aatgtaaatt aaattttatt ttgtttcttt gctagtttat atccttcaat caagtattct
     2521 tcaggtatgg actttaatag cgcatcttct ataacgtctg gtttactttt gtctgattca
     2581 gcaatagtcg tccaatattt gagtgctgac attagaattg gatttatacg aatgctatct
     2641 gctgttctta cactacttcc ttgatctttt atgactttac ttatattttt cttggttaat
     2701 tcgatttctt ctacttcttt tgatttaaaa ttctttttat ttttatttcc tagtaatcta
     2761 cttactgcag cttgactgcg attatcttct gccatcaaaa tcaccaactt cttttaaata
     2821 ttcttctgta aatgctttat agtcatcttc agctgttgag ggtttattaa aattgattag
     2881 atctgatcca gcagcttgcg cttcgtcaac ggttattgtc ctacgaatat aagttttgaa
     2941 aatttttgca ccaatgactc tagaaatttc ggttgctgca gacgtcattt ctttagaaat
     3001 gttataacgc ttattatact tagtaaatag aactcctcgt acttcaagct tgtcgttcgt
     3061 atattctttt accgtttcaa tagtttcact taactttatt agtcctttta atgagaaata
     3121 cgcagcttca actggaatga taatttcatc agaaacagta aatgcgttga ctgtaagcat
     3181 tcctaaactt ggtggacaat caattataat ataatcatag ttgtccttga ttggttgaag
     3241 tactctttta agcctgtgtt cacttcctac ttgagtaaat tccctctctg cagaagaaag
     3301 ggctatgtcg gctggcaaaa catcaattcc tttatagtcc agaatagcat ctgtaatgtc
     3361 agcctcccct tttaatactt cataaattgt aggttggttt gttccatcta tatcgaaacc
     3421 tacattatct gtagcatttc cctgaggatc aatgtccact aaaagtacat ttttaccgta
     3481 aacaaatttc aaacatgctg ctaaattaac gctagtcgta gttttagaaa ctccaccttt
     3541 ttgattggct actgacaata ttcttgccat taaaatatcc cccattcatc ttatattata
     3601 atataattat atcataatat tgtgatattg caatatcgta tatgcattat attgtaatat
     3661 tgtgtgatta ttttgtttta aagatatata tcggttcgga tataaagatt attcatatgt
     3721 tattcgaaat taaaataatc actttttatt actttaaaat tttttattaa tgataagaaa
     3781 tatgttttgc gagcagcaac tagaataatt taaacattac taaactgtct atattgttac
     3841 taataattcc cttcttatag tgcattttct tagaaaaaaa caatattacg atatcatgat
     3901 attaagatat cgtaatatta tacaattgtg attgatatta tatatgtttt tttatttttt
     3961 tatcatgttt aatcttgaag gaatcatatt ctttttctaa agacaggagc ttttcataaa
     4021 catcagacat gtttaaacta gaggccaggc ttaaatcata aacgaatgaa gcaggtaatg
     4081 attttattct acgttgtcgg gttatccagc ttgcaaccgt tccttgtggg taggcatata
     4141 actcacaaaa ttgttctaca gtgattccta aattcttgat aatgtaaaca ttgatcgggt
     4201 gcgagtaaac aaatgtattg atagacatgg tgcgtaagcc tactttcttt tattattgcg
     4261 tttgcaataa tagtttaaca cacgcattat tctagtatct actcctattt gtaaaaacaa
     4321 aaaaggattc atagagataa ctctatagaa tccgtaaaat accttatata tataacggga
     4381 agatataaaa cctaaaatta tgataacctg ctgcagcttc tacatagaaa gagaagcgct
     4441 caacaccaac ctcatttatc aaacgttggc cataacccca aatctcttct gatagctgat
     4501 caaaggttat atactttagc tcatattgct ggataatgtt cattctaatc gactccattt
     4561 attatcctgg taaaattcga tatgacgtat ttcgtcgtag tgaattttgt cttttccaac
     4621 gtagatcccc agctcatcac tacctaagat cttgccaatg atatcttctg gatagtatcc
     4681 ttcagcgttt cgttcttctt tttgaataga tactgatcta ttttttatga ctgcagcgtt
     4741 caatacttcc gcaatctctt cagtcgtcat ttgttctttt gctaaatttt gactggttcg
     4801 ttgttcattg tcggcatcaa tttcttcagt atgatcagat aaataaaacc ctgcccactt
     4861 taaacgtcca cgatcattgt aatcaatcat ttttaattcc cccatttccg cccgcatgac
     4921 caccaacaag tgtgcttcta gtaatgcttc tagcgccttc taacattgaa gaagcatgta
     4981 caatcgacgt aaaaccatat ttttgccgaa tcttgtcaat aattttatct aaattttctt
     5041 cgtcaatttg cttttgtgga tcactaaata aatccagctg aagcgaatcg gtgtacacaa
     5101 gcttgctata ggttattcca acatgcctta cttcttgtcc ttcataatac ttatcaaaca
     5161 agaaaagaca ataattctgc aattcctttg tattatctgt gatagggatc ttcatctggt
     5221 gtgaaaaccc tggtctcgtt tctaagatcg acgtgccaat gtgtaaatgg acacaacctg
     5281 ttttacagtt atgctgccta atgcgtatcg ctacttgttc cgccatttct tttaccacca
     5341 gctcgatttc atttcttcta gtataatctc gtggtaacac ttgtgaattt ccatatgatt
     5401 tttcctttgt cggttctggt gggattgcta tatctgttcg atcgatccca ttagcatgga
     5461 agtacagctg taagccaatc acacctagtc tattcttaat cgtataagga ttccagttag
     5521 caagatctct aatgctcata atccccatct gattgagtct ttttttcatt cgagagccaa
     5581 ttccccaaaa gtccgtcatt tcaggaatat tccatacttt ttcaggaacg ttttcgtacg
     5641 tccattccgc aacaaatcct tcattatgct ttgcttcgtt gtctaaggct agtttagcca
     5701 aaaggggatt atctccgaca cctactgtag caatcaatcc tagctcttct ttaatattct
     5761 cctggatcat ttgagccagc ttctttctcc gttgacttcg tgttccttca gtcgtaaaaa
     5821 gattcagtga tcgggtcact tttaagattg attcatcgat cgagtaaatc agtagatctt
     5881 catcagccac atatcttctg aaaatattat ttacctgcat atttcgcttg atatataggt
     5941 tcatacgtgg tggaacaacg tgtagtgttt taggaaatgg ttgtggtaag tcacgtggtc
     6001 tactcacatt tgtaatacca taccgctttt ttgcttcagg agaagaagct aatatcaatc
     6061 ctgaaccagt attatcagct cgactcataa caacaagttc tgttgttaat ggatctaaat
     6121 ttctttctat acattcgaca cttgcgtaaa agcttttcat atcgattaaa aagtaatcat
     6181 ttactggctc ttttgaataa tccatcataa ataacactcc attctttcac attatacaaa
     6241 catatgttcg atattgtaaa gaagaaatag ctaaatacat aaaaaaagaa gcataggtat
     6301 gctatcaccc tgcttcttct tttgatttgt atgatcaatt tattctatca ctttactaat
     6361 taatttgaaa atctaataaa aactctcact ctaaaagagt gagagactgc aaattagagt
     6421 acggactttt ttggagttcc gttctttaat attaacaaat gaataaaatc cttacaacat
     6481 ttgagaataa gttatcagta gacacttaca aaaaattctc atactatttc ctccatcatt
     6541 agtttttgtc tatataaggt ttaccctaaa tagacactgg tataacattg aaaaatatgg
     6601 cttcctcgtg tatgattagg gtgtatttta aatagttgca gaaagtaggt aaaagttttg
     6661 agagttgcat acatacgtgt ctcatcgatc gatcaaaatg aacaacgcca gattgaagaa
     6721 atgaaaaaat tcggtgcaga gagaattttc atcgagaaac aatctggcgc aacgattact
     6781 catcgacctg ttttccaaga agcattagat tacgtccgag atcaagatat ttttattgtg
     6841 gaagctattg atcgacttgg aagaaattat gacgagatca tcgcttcagt caattacttg
     6901 aagaagaaaa atgtgaagct gatcattact agtttaccga tcatggctga agcaattggc
     6961 aatcctctcc tggataaatt cattaaggat ctgatcatcc aaattttggc catgatcgct
     7021 gaacaagaac ggactgaatc gaaacgtcgc caggcacaag gaattaagat cgcaaaagca
     7081 aacggcgtct acaaagggcg gcccaaatta tacagtgcag acgcaaaaga tccccaacgt
     7141 cgccttgttt acaaaagcat cgttgaagat cttaaaaatg gtgttgcgat tgctaagatt
     7201 gctaaagact acaatgttac gagacaaacc gtgtatagaa taaaaaaaga cagcatggtc
     7261 aatgacaaat agttgatcat gctgctttta ttatcttctc atctttaatt tcctacatat
     7321 aattactatc tataaaatta agtcttactc agaacagata aagcataaaa ttccaacaaa
     7381 ccatttttta cttaactaaa taaagagtct gttaatataa tcttcactta tttacgttaa
     7441 tcccctactg tatttgttgg ttccttatct atattttcta caaaatcctt attatcttgt
     7501 gatttagctt cgtataattc tttgtatgtc gacacattgg ttatactaat tcctatagct
     7561 agttcttgag actctacttt tctctctagc tcctttgaca aagtgatttg agatttattt
     7621 ggttccgttg gagtcaattc tatagattct tcataaaaat ctctatacat aaagctatcc
     7681 ctgaataatt catagcttta attctttggc acattttatt gaaatatgta tcactaatat
     7741 ccctatcaac tgattttgac taaaaagtta cttcaaacat tcactgttca aaaatattga
     7801 ggaataaatt ttgggtgtaa ggcattttga gcatacttct ccctggataa cttcccagta
     7861 aaaaaatcgt tagattgttg gattagatcc attgactggc tcgcctcagg cgagcaaaga
     7921 ccctgtagaa ttcattctga tacacatgat aactagataa tttgagatag actcgtctac
     7981 ccgtttggac taatttccca gcaactttca gaaacttcaa tcgaatagaa tgaatggtca
     8041 ttcccttttg gacttcttca aagccaatcg ttcttaagaa gttgactaag ttgtaagcta
     8101 tcaagctgag catcattcgg acatgattct ccaaaaagcg aggactgtct gttttgtcaa
     8161 agtaaaagcc agctttcgct tctttaatga agttctccat tgtgccacgt ttggcataga
     8221 tagaaaagat ggtatcagga gaaacatttt ctgatagatt cgtcacgata aattcatgtc
     8281 gaaagagtag ttcgcccgct tcacgtgttg agcgtataca cacgcgacga ctttgtgacc
     8341 aggattgtgc ttgataagtg gtcgagaagt actgaacttc tcgttcttcc cacttttgat
     8401 tatcgccata aagtactgat ttctcagcta tttgacctag tctacgatta ttcttcagtc
     8461 gaataacata atgactcttt tttgattcac acgaatcata cacaccaggt gtagcgaacc
     8521 cgctgtctcc acgaaccaag atgtcagtgt ttggtagaga gtgattatag tgctctaata
     8581 aaggtgtgag aaactccttt acgccttttg atgtatattg atttcctgaa cgtagttcag
     8641 cttttaagaa gtcaccagtc aatccgtcaa aagctaccaa tggatggtaa ccataggttt
     8701 ggtagtgtgt attataattc gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat
     8761 ctaaatcaat gattaattcc gtatcattac ggatgaggcg tgctttatcg ataagttctt
     8821 ggttcaaagc ttgaagttca tggatattct cctcagatag tcgatctaaa aatcgggaaa
     8881 gtgaagattg agaagcgagt tctttcctat ctaaaacagc tttaaacaca ggatcttgtc
     8941 tcaggagatt agctgcagaa tcagctgagt aaccagcaat taattgcata atgaactgct
     9001 caagtatgga taagttgtca tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt
     9061 gcttagccag ttcagaaaaa ccaaagatgt tcatcagctc tttcactagg acgagacccg
     9121 aatcactcga taattgacca cctgtatgag aaatagtgat atttgaattg aattttactt
     9181 ggtttttgtg taagctagtc atgaaaagaa ctcctttctt ttggttggtt tagtcacttt
     9241 aaccatagca gaaaggggtt cttttttcat cacttaacgg gtgaagatga aaaagtaatt
     9301 gtaagctgcc gtgaggcagt ttcacatggt tttaattaaa agtatgaatt attcaggcta
     9361 tcattaattt tataaaaaaa attaaatgtt tttagcactg ccatataaca ttcaaaacat
     9421 tcttctatag ttggtttact tccttgagga gaatgaacca atttattacg tttttctatg
     9481 aaatttttaa tttcctttct tatttctttc ggaaactcaa tattaaagta ccctttaaac
     9541 atgctcccta ataatttgtc tacaggggga gattgtaaat tctcaaatat tagagttaaa
     9601 tcaggtttct cttgttgata aaattccttt acccctattt cacaggctgt aattatcgaa
     9661 ataaacctat ctctagtatt tgatatattt ttacttcttt taaggagtat aagagaaaag
     9721 gggatacttt cgtgtccatg catgtaatta actaattgtt gagcttcaga agttatatct
     9781 ctaattatat agttaacgga attaggaagt gtctttaact ctaatgaaat ttctatccaa
     9841 ttactatctt ctaatctgta tatgctcgaa gtataatttg attcgtcagc aagcatcgct
     9901 acatcccaaa cactgatcat aaaatctttt aaacgttcaa tcatttcagc aatattgcta
     9961 aaatcagcta atttttcttt agaataaaaa aaaacattta tatcagaatc aataaattct
    10021 atttttttat tactatatcg tcatcattat cttgaccatt tatgtttatt gttccctgag
    10081 tggggagtac ttctttcaaa ttcaagttaa atttatattc cattacttct cctccaatat
    10141 ataaaaatta cttaactgta tccaaattta atatgtaaat aaatcattaa tttttagcta
    10201 aattctatga gaagtttatt tttgttgttt ttgctaatta actaaaacta gtacaaaaaa
    10261 tttaaaatag attattaaac ctattgctta ttctattcag tcatatatat aagcgtcatc
    10321 ctttagtaac taacatccca cactacaata gtattataac atatctattc aacttcaaat
    10381 tgttgaaatt taagccattt atatttactt ttcctcaact ttagaaatga ttttactaac
    10441 cttatatccg taatacgcgt aacaaacaca ttcattaata acaatcaaca ctaagctata
    10501 ttagcttttt aaatgactag ggtaaataaa ataaggatca aaaactttta agtttctgac
    10561 cctttcctta cttccgattg gttaatagtg atcttttgca gaataaataa atatcgtttc
    10621 attttcaact ctatatatca gtctatgttc atctgtaatt cttctggacc attttccaga
    10681 taaatcatgc tttaatggct caggttttcc taatccagca aagggggaac gatcgatatc
    10741 ttttattaac ttgttaatct tttttatatt gcttttgttt ccttgctcat gccaataaag
    10801 ataatcatcc caagcatcat cagaccaagc cttaatcatc agattcaacc tcgattaagt
    10861 catgtgtttt aaatgcacct ttggagaatt gttcatctcc tcgacgaatt ttttccatga
    10921 cgtaattatt agaaagtgtt ctcaacgttt cttgcataga atcataatct ctttttgata
    10981 atacaacaac tgtatcttct acatctttac ttgttacaat aagtgtttca gcatcctcat
    11041 taacttgttt catataacta cgtaaatttt ggcggaaatt tgaataagct actgcttcca
    11101 ttcctttcac cccttattta tttctataaa acaattgtac attatattgt acaattaagc
    11161 aaatgattaa tattctaact tcttataatt aaaagtgcta tcacttttag tttttaggat
    11221 aaaaagtgac gtcacttttt gagtgctggt acctcaaatc ctgctttttc ttgggcaatc
    11281 aataaatcta acgcaataca cataatcctg gattcacttt tgccgtactt ctgctttagt
    11341 tgctgcaatt ctttttgtct cttttcatcc aacgtaacgg gtaaccgttt atttcctatt
    11401 gcaattggca ttagtactct ctcctttcat cgaaataacc ctatgaaaaa tatggctgca
    11461 atcatcttga atagtagact cacaagggct aatacaaagc gccaaaagat caaacaaaat
    11521 accagtattg ccaaaaatac tacgaagttt aaatgcacag ctgcagcatg gcgcataagt
    11581 atttcgccaa caaataggac taacaataga ggaatgattt tattcatatg gatctccttc
    11641 tttctcttag gttatcgggt gttgcccgct tatttcgcac cacctaagcg gcgggggcgg
    11701 ttggagcgat tggtgcgaaa taagaaccat tcccttagtt actaggtttt ttgtccttat
    11761 ttcacacatt ctcacttttc ggtataaatg attattgcct ttttttcctt tcaaatcgtt
    11821 gatatggcat tcgtttacgg tcaagttcat tttggatttc ttctgtatcg tcgtaagtat
    11881 aggtgtctaa aaaatcagtt aaagtcgt
//
LOCUS       DAZAOD010000081        11755 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000081 DAZAOD010000000
VERSION     DAZAOD010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.083"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..177
                     /locus_tag="ACHDPO_002178"
     CDS             <1..177
                     /locus_tag="ACHDPO_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369789.1"
                     /translation="YLLGMALAYSVGSLIKVNVSLDLFTILLAVGVSSVIGLVFSVMP
                     ASEAAKKDLIDILR"
     gene            578..1183
                     /gene="fic"
                     /locus_tag="ACHDPO_002179"
     CDS             578..1183
                     /gene="fic"
                     /locus_tag="ACHDPO_002179"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFN3369790.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1199..1771
                     /locus_tag="ACHDPO_002180"
     CDS             1199..1771
                     /locus_tag="ACHDPO_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3369791.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2023..2280)
                     /locus_tag="ACHDPO_002181"
     CDS             complement(2023..2280)
                     /locus_tag="ACHDPO_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369792.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2406..3221)
                     /locus_tag="ACHDPO_002182"
     CDS             complement(2406..3221)
                     /locus_tag="ACHDPO_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3369793.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            3738..5063
                     /locus_tag="ACHDPO_002183"
     CDS             3738..5063
                     /locus_tag="ACHDPO_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFN3369794.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5056..5406
                     /locus_tag="ACHDPO_002184"
     CDS             5056..5406
                     /locus_tag="ACHDPO_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369795.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5403..5573
                     /locus_tag="ACHDPO_002185"
     CDS             5403..5573
                     /locus_tag="ACHDPO_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369796.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
     gene            complement(6477..6752)
                     /gene="prgO"
                     /locus_tag="ACHDPO_002186"
     CDS             complement(6477..6752)
                     /gene="prgO"
                     /locus_tag="ACHDPO_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFN3369797.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(6724..7677)
                     /locus_tag="ACHDPO_002187"
     CDS             complement(6724..7677)
                     /locus_tag="ACHDPO_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3369798.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8289..9782
                     /locus_tag="ACHDPO_002188"
     CDS             8289..9782
                     /locus_tag="ACHDPO_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFN3369799.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            9917..10213
                     /locus_tag="ACHDPO_002189"
     CDS             9917..10213
                     /locus_tag="ACHDPO_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFN3369800.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10314..11165
                     /locus_tag="ACHDPO_002190"
     CDS             10314..11165
                     /locus_tag="ACHDPO_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369801.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11186..11398
                     /locus_tag="ACHDPO_002191"
     CDS             11186..11398
                     /locus_tag="ACHDPO_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369802.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4041 a         1811 c         2179 g         3724 t
ORIGIN      
        1 tatttattag gaatggctct tgcttatagt gttggttctt tgataaaggt aaacgtgtca
       61 cttgatctat ttactatttt actagcggtt ggggtatctt cggttattgg actggtcttt
      121 tctgtaatgc ccgcttcaga ggctgcaaaa aaagatttaa ttgatattct tagataaaat
      181 cagaatgaca agaatattta cgttctagat tctaaaataa aacacaaaga gaccaaccag
      241 gcaccctatt gtttctttgt agtatagaga tattctttgg cttgtaagag atcaatagag
      301 ttaggtgacc ggagttcgaa ataaaggaaa tttttgattg tataggagaa ttctttatcc
      361 ctaatattta gaattttgag tatgccatgt tgatgtttta gattctctat aaatatagag
      421 gtgtatcaaa ggtcaactag actgtgcaaa atagagacac ttgaaaaatc tatcgggggt
      481 cagaaactta atagtttttg acacataaac aaaatcgcga tataatgggg ttgagagtgt
      541 ttcataaact tatgtcataa agttaaggag atttcgcatg attttagaga ataaattggg
      601 attaaccaat caagttgagt tggctaaggt tgaagaaaaa ctcagtaaac aaaaagcgaa
      661 agaattgtac gattgtggaa aaataaatga aatcgaagtt ggtacattta aaggtttatc
      721 tgaaattcat gaatttctat tttcggatat ttacgatttt gccggaaaaa tccgatcggt
      781 caatattgca aaaggaaatt ttcgatttgc accagttatg tatttagaac attcgttaca
      841 gcatattgat cagatgccac aaacttcttt tgaagagatt atcaagaaat atgtggagat
      901 gaatatcgct cacccatttc gagaaggaaa tggccgaagt actagaattt ggctggatct
      961 cattttaaag gaagaattgc aaaaagttgt agattggaac ttaatcgata aagcagacta
     1021 tctttctgca atggagcgaa gtcccataaa cgatttggaa atacgctatc taatttccaa
     1081 tgctctgact gataaaattg acgatcgcga gttatatatg aaaggaatcg atgtcagcta
     1141 tttctatgaa gggtattctg agtatacgat agatgatttg taaaagtagg tggaccaaat
     1201 gacgaaatat ggatatgcac gtgtctcaac cgcttctcaa agtacaaaag aacaaattca
     1261 acagttgctt gagaacggcg tagagaagaa gaatattttt tcagaaaaat ttacgggtac
     1321 aaaacgggat cggccaaaat tcaatcagct gttggctggt ctgaagcctg gagatgaaat
     1381 agttgttacg aagcttgatc gatttgctcg taacacgaga gaagcattag agatcattga
     1441 acctttactc gatgataacg taacgatcaa ggttttgaat ctaggaacga ttgaaaatac
     1501 gtccatgggg cgaatggtga cacggacgtt gttgagtgta gcagaaatgg aacgtgatat
     1561 gattgtggaa cgtacccaag aaggaaaaat gtttgcaaga aagaataatc ctaatttcag
     1621 agaaggacgt ccgaaagcaa caatcacacc gaagaagagg cacgcatatg aactgcttac
     1681 ttcaggtaaa tcgtataagg aagttgaagc tataaccggt ttcagtcgca gtacgctttt
     1741 tagaataaag aagaaaattg aagaaagtta aaaaagaagt ctcagcgaac cagacaggta
     1801 aatacttaat gcgttctaga tatgagtcta ttagcatgtt gtgaaatata atattttttt
     1861 atttacttga tttctgctca aaaaatgtgt atggtaactg taaaaggtaa agtaattaaa
     1921 ggtatgctag ccacgcttac tatattagga taccatcata tatttataat gaacgatttg
     1981 ttcgtctacc aaacaacaca tatcgttcag cgtaagtcac gtttaggaac gtggcttttt
     2041 tagtgttatt atcgataaat aatctattga ctctattgat tttatctcca tatccctacg
     2101 gtgttgattg tctttagatc tttcatttaa gaaccaaata actatcataa aaatcagcac
     2161 tgctgctaat ataataaaca gcattcctat tgtgatatta cctattgatt ttaccataac
     2221 tacgattaaa gtaataatgg cattcaagtc tcctttgttc tctatatata aattagccat
     2281 aaatcatctt cctttcaaat taagatactt gtttgatacc aataaatagt aagcgtggct
     2341 agcatacctt tttctgtaat agcaagtgtt ctaatagtcc aaacttaatg atggaccgat
     2401 gctagttata gtacagtaat gttttctttc ttatctagat ttttagtaag ctctatcagc
     2461 aaatctaaca aatctgagtc cttttcagaa actaaattaa atctagtgtt tacaacaaag
     2521 ttttcatgtt ctatattgtt tagattattt gcggaaagga gggcttctag atcttgacat
     2581 tcaaatctat atgcatcgtc ataaatctta ctagaaggag tgcttaattc gaaattactt
     2641 attttctcat cttggaccaa gataaattta tagatagtat ctttttgtgt ttttctttta
     2701 aaaacacaac agagtgtgtt ataaggaacg ttataatttt catcagcctc attttttctc
     2761 cattcaaaca aatgataaac tgcaaccaag ttgccatcaa tttcatggac agtgctctcg
     2821 gtaacatcct ttaaagaact atcaagggct aatttatagt aactagagag aggaagtaaa
     2881 attgtcgatt tactgagatg gttatcgtct atacgtgcaa tcatacctaa atcaactaag
     2941 gttttattcc aggtgtttat agttttagtt gtcactccta gagactctgc tatggtattg
     3001 accgaatgcc aggaatcccc gccttcattc tttgccttaa aacagtaata cagatataaa
     3061 ttaatagctt tgttattcgg taaatatttt tcaagttctg ttggtagaat aaagtaagaa
     3121 tccttaatgt tttttctgaa ctgtctccag tctctgtagt tttgtttata aagttgtgaa
     3181 acggtttttc cacctttaga aagtcctgct atcttaacca atcttattgc tcctttcttg
     3241 aatctgtcat gatcatacag tattttttac ttgtagtcca gcaccttaat atattatcct
     3301 atgtaattaa tttcgtacta gatagtaatt attttttatt taattctcta gtcacttaca
     3361 aataagttat ataaactacg attaataaat tattacaaaa actattaaga aaacttctac
     3421 atacaactat tacaaaacta ttaagaaact gaatactcct attttttgtt tttaaggaaa
     3481 gttttttctt ttttgaattt cttatttttt tctaatataa ctaagcaaaa ctggataata
     3541 cgacacttat tttcaaattt tcacaagact aatagtaaat atccatttaa taaagtgata
     3601 caatgtgttg attttacaaa tcaacagaag aagtagggaa ataacttacc tatgcttctt
     3661 tttttgtaca tttaatcgat tcttctttac aaaaacgaac gtatgtttgt ataatgtgga
     3721 agaatggagt gttatttatg atggattatt caaaagagcc agtaaatgat tactttttga
     3781 tcgatatgaa aagcttttac gcaagtgtcg aatgtataga aaggaattta gatccattaa
     3841 cgactgaatt agtcgtcatg agtcgagcgg ataatacagg atcagggttg attttagctt
     3901 cttcaccagc tgcaaagaag aagtacggta tttctaatgt cagtcgacca cgagatctac
     3961 cgcaaccttt tcctaaaacg ttacatgtcg ttccaccacg catgaatctc tatattaagc
     4021 gaaatatgca ggtaaacaat attttcagaa ggtatgtagc agacgaagat ttattgattt
     4081 actcgatcga tgaatcgatc ttaaaagtga ccagatcaat gaatcttttt acgactgaag
     4141 gaacaagaag tcaacggaga aagaagctgg ctcaaatgat ccaggagaat attaaagaag
     4201 agctaggatt gcttgctaca gtaggtgtcg gagataatcc cttattagct aaacttgctt
     4261 tagacaatga agcaaaacat aatgatggat tccttgctga atggacgtat caaaatgttc
     4321 ctgataaagt atggaatatt cctgaaatga cagacctttg gggtattgga tctcgaatga
     4381 aaaaaagact caaccaaatt ggtatcatga gtattaaaga cttagctaat tggaatccat
     4441 acactattaa gagccattta ggtgtgattg gcttacagct gtattttcat gcgaacggga
     4501 tcgatcgaac agatatagcg atcccaccag aaccgacaaa ggaaaaatca tatggtaatt
     4561 cacaagtgtt accacgagat tataccagga gaaatgaaat cgaactggtg gtaaaagaaa
     4621 tggcggaaca agtagctatt cgtatcaggc aacataactg taaaacaggt tgtgtccatt
     4681 tatacattgg cacgtcgatc ttagaaacga gaccaggttt ttcacaccag atgaagatcc
     4741 ctataacaga taatacaaag gaattgcaga attactgtct tttcttgttt gataagtatt
     4801 atgaaggaca agaagtaagg cacgttggaa taacctatag caagcttgtg tacactgatt
     4861 cgcttcagct ggatttattt agtgatccac aaaagcaaat tgacgaagaa aatttagata
     4921 aaattattga caagattcgg caaaaatatg gttttacgtc gattgtacat gcttcttcta
     4981 tgttagaagg cgctcgtagt attactagaa gtacattggt tggtggccat gcaggcggcg
     5041 caggagggct taaaaatgat tgattataat gatcgtggac gtttaaagtg ggcaggtttt
     5101 tatttatctg atcatactga aaaaattgat gccgacaatg aacaacgagc caatcaaaat
     5161 ttggcaaaag aacaaatgac gactgaagag gttgcggaag tattgaacgc tgcagtcata
     5221 aaaaatagat cagtatgtat tcaaaaagaa gaacgaaacg ctgaaggata ctatccagaa
     5281 gatattgtta gcaagatctt aggtagtgat gagctgggga tctacgttgg aaaaaacaaa
     5341 gttcactacg acgaaatacg tcatatcgaa ttttaccagg ataataaatg gggtcgatta
     5401 gaatgaacat tatccagcaa tatgagctaa agtatataac ctttgatcag ctatcagaag
     5461 agatttgggg ttatggccag cgtttgataa atgaggttgg tgttgaacgc ttctctttct
     5521 atgtagaagc tgcagcagga taccataaat acgaatacta tattggctat taaagtgcaa
     5581 taaaattata tttcttttat gttttacatt ttgtatcaat tctgataaaa ttacctatag
     5641 gtaattaaaa aatataaaaa aactagttac aaccttagga cgttgtaact agcttgaagc
     5701 atactagagc taactaaaat agcactagaa agcaatgtta aacccgtcca acaaacttga
     5761 tttaacattg agaccagctt attcagctaa atatagttga ataagcttct tttgttttaa
     5821 aaaaacaaaa ggtgtactac gaataacgca agtaaaagaa atactattac aaccagtagg
     5881 ctacaagtaa gtattactaa acattgcgta gttagaacct ttgctctatt gtctaaagcc
     5941 acaaaattag agatcagctt tatgatgcta agagcgagct gcatccatgc ggacataggt
     6001 tcttttgaca ctattaattc tcctttttag gataagggaa attgctagta gttttttcat
     6061 tagcaccatc ccccttcatt tgattgagtc tagtgctgct gtgatagttt gctgtttaat
     6121 atgcttacat tcttattata acataaatga aacaaacaca tggttagagg tcgtatcaat
     6181 caaaatagtg tctcacaaac gatttattac ttactcctgc tgactaacgg actgttcttc
     6241 agtaactgta actatatgtt tgttaaaacc accattacct gtagataaaa accaatatat
     6301 ttactatact cactatatta aatatattta gtatagtaaa aactagaaac aataaaattt
     6361 gtgaatgttg tataccccca aacaatacac atattttgaa ggattaggat taataaagct
     6421 aaaaatatag taagtatact aaatatattt actatatcta gtatacttac tatattttaa
     6481 tcttttgatc gtctattata tataatccgt tcctcgtcgt ttaaagtatc aacataggcg
     6541 tccattgcaa gtttgactat ttcatacata ggaatatctt ttgcataact aagatcccga
     6601 atggttttta gtacgggagg atctacttga actggttttc tttctttcgc agtgtacttt
     6661 cgttccccta actcgacatt aatatcatct ttaattgaaa tatcttcagc accaattttc
     6721 ttcttatctt tgttcgttgg taataatgcc atttagttta atctcctttc caagaggtag
     6781 gatatgattg gccattgagt cagcatattt aggtgtataa tcaaatcctt caatatcacc
     6841 atgttgttca tagtattcaa ttctttcttc taattctgta aagatgtctg caaaaatagc
     6901 ccaccatctt cgatctacat aatcatttaa ttggatacca ttctcaccat acatttctaa
     6961 ccgatccgag cctttaacaa tgcttttaaa aatgtttgat tcaccatact tatcaattgt
     7021 tttttgatag tttgcgtgtt gagaggaacg tcgcactgag aaaagaacag gcaaaattcc
     7081 aatgatttga agatgagact cttcaaaatt cgtgacaatc ggaactaaaa ctttattaat
     7141 aaaatcttct gttccttcca ttgcgtaccg ttttaattct tgcattgcaa taatataatc
     7201 tgcagcagtt aagaatgcac gaaccacatt atctgttgat ggtgggcagt cgataaagat
     7261 ataatcgaaa ttttttctca attcttctaa aggtttaatg aaggccaatg atctcttacg
     7321 acgatcagga tatttttcgg acaagtattc attaagttct tcagatccag gagagccagc
     7381 cataatatat aaatgtggac ttacttgagt aatacctgaa acccagtccc cttttttgat
     7441 tgctgcagac atggatcgat caaagctagt aatttgatac gttgatccaa tgttggaagt
     7501 agtatttctt tgttggtcat aatcaattag caacacgtct ttttcaaaaa gttgactaga
     7561 aacaatcgct aataaatcat tgtctgtagt cttaccaatg ccgccttttc tacctgtaag
     7621 cattacaact tttcctagtt tatctgatgt tttaaatgca gtccgtaagt tttccatagt
     7681 tccctccaat ttcctatact aaatatattt agtatacttc atatacttaa tatattcgat
     7741 atatctaata tactccaaat tgataagaat tcagacttta taaggaatat agtggatata
     7801 ctaaatatat ttgctatatt cagtatatca gatatattca aaatgtcaaa atatatttgt
     7861 gcgttttgcg ttgacaattt agagtgaaaa gaggtaaact taattctata gaaaccacag
     7921 ataattcact atttacaaag tagcaaaagc agtggtactc tttaaacaga aaaattacat
     7981 aaaaaaaaga gacggaaata attgatttta gcagaatcaa ttatttctga atcacatggt
     8041 taggacatgt gttcacgctc gtctcaagaa tatgtaagta gctaccaact acttatatta
     8101 aaagttgatc ggataccttt tccgattgcc tttattctac caaaaaaagg cgagcaactc
     8161 aacagaagaa cgtttattta gtgtacttaa attaaatatt cttaaacact gaagagagaa
     8221 cacatactat ggctgagatt aaagctaaac tgtgttctct ttttgtttga gaaaggacgt
     8281 tacaatcgat gttgagcgaa atttattcag ctattcttaa aaacggctta cgtacataca
     8341 aatatcgaaa cagcaccatg aaacctgcag gtcatattga ttccagtagg agtggtgcta
     8401 tctttgcgta ccgtagcaag caattaatga atgttgggcg tggtatggtc attacttcgg
     8461 aagaagctat tttagagaac gaaaagaaac taacgcattg gacacctaat acctatcgct
     8521 ttggtactta tgcggatgat tatcgaacag tggttaaagg tcattctgag aaaaacttaa
     8581 gtcaaatcaa cacatttgta gttgatatcg attcaaaaga gaaccatcaa ggcgaaatta
     8641 ttttagcctg tttagatcaa gtgggctaca tgccaacgct aattttagaa tcagatcatg
     8701 gttatcaagt ttattttgta ctaaagacac caggctatgt cacaaagaaa agcaatttca
     8761 aggtgatcga tgtagcaaaa aaaatttcaa aaacaattcg tctacagttg gctgaaaaat
     8821 tgtccggagt ggatctagga tgtaaccact tcggaattgc tcgattccca caagaaaata
     8881 atattgtttt taaagaaatg aactatcagt attcttttgc tgactggatt caatggtcga
     8941 tgaagcttga atcagatcaa aaaacaaaag aagatcgaga acgaaaacta attgtctttc
     9001 ctgagaaaaa agaaattcgt caagtagatg aaccgtggtt cgatatgtta cttcataaag
     9061 caaacatcgt cggcggagaa ggacgtcttg gtcgaaataa tgtgattttc acgctttctt
     9121 tagcttatta ctcttcaggt tatgcattgg atacttgcga atacaatatg ttcacattca
     9181 acgaacggtt acaggaaccg ctatctgaag cagaattagt aaagattgta cgtagtgctt
     9241 attctggtaa ttatcaagca gcaagcagag aattcattat tgaattgtgc cagcaatggg
     9301 tttcaccaac cttaaaaaat aatgatctgt tcattcaacg acgtggctgg tggaaattta
     9361 aaaagccacg agatcaaaga aaatatagtc ataaaaatga atggaaagaa gatctattgg
     9421 cttatctaag cgaaaaaagt cttgctagtg agccttattt gaacctgtca aaaaaagaat
     9481 tggcttcaca actaacgatg cccaagcgaa cacttgataa gatcttaaat gagttacgag
     9541 aggagaataa agtcttctac aaggtaacac gaggaagaaa tggcggaatg atcattgctt
     9601 cagtcaaaac gttgttcgcg agggttattc aactaagtaa agaaaagaga ctagattatt
     9661 caacaaggat cacagaggta tttggactca acgagagctt agtagaagag acatttagac
     9721 aattatcaac ccccttgaac cctcttaaag aagtgaatct ttttgaagta gatacaggtt
     9781 gaaaaataaa aggtgcaaat tgccttatac aatatatcta tgatacttct gtaggtgttg
     9841 ctccctttgc ctagctacgt gtaggtggta tacttataac tgcgtatgca gtcttatgta
     9901 tcatggagga agttgtatgt cgttaaaaaa ttatgtctat tcacatcctg ttaatgtgtt
     9961 tatcattggt cgtttgggat tatctgtgga agtgttctgt gagctttatg gttttaagca
    10021 ggggactttg tcttcttggg ttaccaggga aaaaacagtt gcttctttgc cgattgagtt
    10081 tcttcatggg ttgtccttag cttctgggga gactatggat caggtatatg attgtttgtg
    10141 tgtgttagag caggagtata ttgagtataa aatagctaac gagttaagaa aaaggaagaa
    10201 gtatatccag tagtagtttt tatttactta aaaaattggt tcattgagca acctatcgct
    10261 gctaaagtag caaaggaaaa cgttaaagga aagaatttag ggaagaaatc gaaatgaaat
    10321 cggacgactg gattgaacac acctggcttc ctctgaaaag aaatagcaaa cgaaagaaat
    10381 tttgggtatt gcaattatgg ccattaggaa aactttgtag ttacggggca cgacttattc
    10441 ttgatttaac cgtttactcg attggagtat ttggaacggc ttattacttg ataaatgatc
    10501 ccaataggat tgcagcatca gacattttta cagtgctaat gacgttgatt tttgtcatgc
    10561 tattgtctat ttttactcaa ttagtcatgc aatttaccag gcaaaaatta acagcaggaa
    10621 aacttttcaa aagcctattc gatttaattg ttgtaaatgc aattctagcg actttaataa
    10681 aacaaattga acaatctgga agaacaacaa aaggagtgaa ggatttttta ttgacgttta
    10741 ttcactttgt aaatggacac atgtatttgt ttgaagtggg tattattctc ttttttgtcg
    10801 ggtatgtatc cacgaaactt attaaacgtt caattgaaaa agaaattgaa attgacctga
    10861 ttccgacact tcttggttat gagtacaatg ttgattttgg aagatatgac gaattgatca
    10921 atacggatat cgttcacacg agtatccatg aatctactgt taagggcatc agatctattt
    10981 taaaaaatgg ccaggaaatg aaagcaatag atcgaagaaa agagatctac aatttttatg
    11041 aagtcgaagc aagcctacga tatggcatcg gaaaattgtg gttagatgga agtaatattc
    11101 gtcaaaacaa accatacatt ttttggaaca gtagtgattt agaacttcca atgaaagata
    11161 aataattatg gagaatcgtt tgaaaatgat tcctctatac aggattgtgc ttatagttgg
    11221 catggagtta aaaaccttaa agaaggagca gttattcaaa gtgaaagaac gtcataatca
    11281 gttactatgt agtaaaacgg gtacgatgaa cattgaatac cgaacagaat atttagaatt
    11341 aacgaatcaa actgattttt tgttgattcg aaagcaacaa gagcaagaaa aaaattaatg
    11401 gctacttata gccaattgat tgatgaatgg gaacaattca aggaatctaa aattccagaa
    11461 cgtctctaaa agcctttatt tgtaaagagc ataaggaaac gtgggaacac tttttaaaaa
    11521 aagtgttcca ataggctgtg cctattacgt ttctcaaaaa taaatgtggg aacaaaatat
    11581 ttaaaaatag gatagtgaaa ggatagtgaa ggatagtaaa aggagggtag taggatagca
    11641 aaaaggatag gctccttttc gctatccttt ttaaattgga ggaattaata tggaagtaag
    11701 aataagaaat gtggatgaga aaatcgtaag agaaattgat cgaagatgtg acgaa
//
LOCUS       DAZAOD010000082        11600 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000082 DAZAOD010000000
VERSION     DAZAOD010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.084"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(113..490)
                     /locus_tag="ACHDPO_002192"
     CDS             complement(113..490)
                     /locus_tag="ACHDPO_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369803.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(790..1671)
                     /gene="galU"
                     /locus_tag="ACHDPO_002193"
     CDS             complement(790..1671)
                     /gene="galU"
                     /locus_tag="ACHDPO_002193"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFN3369804.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(1714..2733)
                     /locus_tag="ACHDPO_002194"
     CDS             complement(1714..2733)
                     /locus_tag="ACHDPO_002194"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFN3369805.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(3366..4370)
                     /locus_tag="ACHDPO_002195"
     CDS             complement(3366..4370)
                     /locus_tag="ACHDPO_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFN3369806.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(4383..5432)
                     /locus_tag="ACHDPO_002196"
     CDS             complement(4383..5432)
                     /locus_tag="ACHDPO_002196"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFN3369807.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(5449..6270)
                     /locus_tag="ACHDPO_002197"
     CDS             complement(5449..6270)
                     /locus_tag="ACHDPO_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFN3369808.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(6257..7036)
                     /locus_tag="ACHDPO_002198"
     CDS             complement(6257..7036)
                     /locus_tag="ACHDPO_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFN3369809.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(7053..7523)
                     /locus_tag="ACHDPO_002199"
     CDS             complement(7053..7523)
                     /locus_tag="ACHDPO_002199"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3369810.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(7535..7954)
                     /locus_tag="ACHDPO_002200"
     CDS             complement(7535..7954)
                     /locus_tag="ACHDPO_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3369811.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(8035..10812)
                     /locus_tag="ACHDPO_002201"
     CDS             complement(8035..10812)
                     /locus_tag="ACHDPO_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFN3369812.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            11003..11227
                     /locus_tag="ACHDPO_002202"
     CDS             11003..11227
                     /locus_tag="ACHDPO_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369813.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
BASE COUNT         3342 a         2449 c         1892 g         3917 t
ORIGIN      
        1 aaaaagattc ttttatataa gtgaaaaaag cttttttcca ccaattaaat aaatctctca
       61 tctcaatagt ttatccatta ttttatcttt ttttgcgtat acctactaaa tattaccgtc
      121 ttcttctcgt tcttctactt tgttcgagag aatctgtact agaaaaagta gttgtatgtc
      181 taccttttct gcctatccga gactttcttt tcatatatgg gatataaatg attagataca
      241 gtacagcaaa aaataaagca aatacgcaag cttcccaact acctaacgcc aattcaacca
      301 tcaaggtagc aaccccaacg gatgctgcat accagataaa aatcagaaac gtttcttttt
      361 ttctgaccat gcgaaacatg ataaatagac taataagcaa tagtggcaac acaaatatcc
      421 aattgcttcc ttccatcagc cacttgagta tatcaagcag cgactgtgca acagcgacta
      481 attttcccat agtgaacaca cacctttttt tataattaaa aaattcgcct ttttattcta
      541 ctatgaatct tctggcttgg ctttcatttc tcttatgtaa tcattttctt ttatacaact
      601 taaaaaaaaa ttaaaccatt agcataatat tttctgaatc tattcacgaa agtctttttc
      661 tatctttcgt tttccacgac tcaactgatc tagagtcaaa aaactaaaac gacagttgcg
      721 caaatgacgc acaagctgcc gctttaataa caaatagcct ttcattctca gcaggccact
      781 tatttccagt taactttctg ttcttagctt tttactcaac tggataatat atgcacttaa
      841 tgaagtccca atttccgaat gttgaagtcc atattcaata tttgtcttca tatatcctaa
      901 cttatcgcct acgtcgtatc tttttccttt aaactctctc gcatagaccg cctctgtctg
      961 gttaagagtc tgaagtgcat ccgttagctg tatctcgttt cctgctcctg gttcttgagt
     1021 ttctaatatc tcaaatattt taggagtcag tagataacgt ccgataatgg ctaaattact
     1081 tggtgctttt cccatttcag gtttttctac aaaccctttt actctgcaac gacccttttc
     1141 gctatctgtt ttaggatcaa taattccgta tttagatgtt tcattttctg gtacacgcat
     1201 gacggcaaca gcggaagctt gtgtttcttc ataatccatc atcaattgtt gagtcaatgg
     1261 gatatcatct ttcatcaaat catcccccag catgacgaca aacggttcat ttcctataaa
     1321 tgcttttgct tgaagcacgg catcccccag tcctcttgga tgagattgac ggatgaagtg
     1381 aagattgact tgagtcgttt cttcaactaa agcgagtaat tctgtttttt ccttttcccg
     1441 caaattgttt tccaattcga tatttgcatc aaagtgatct tcaatgggtc ttttttcttt
     1501 tcccgttacg atcaagatgt cttcgattcc cgaatccaat gcttcttcca caataaactg
     1561 gatcgttggt ttatccacga ttggaagcat ttcttttgcc atggcttttg ttgccggcaa
     1621 aaaacgtgtt cctagcccag cggcaggaat gactgctttt ttgaccttca cttgctgttc
     1681 ctcctaaacg acgattaact attgatcatc tatttaacga agagaaaatt cattctccat
     1741 ttttccgtca cgtaacatga tttcttttgc tgcttttttg atatcttctc cattatacaa
     1801 aacattatag attgtttgag taattggcat ctcaacacct agctgttgag ctagctctac
     1861 tgctgctttt gtcgttgcca caccctcaac gaccattccc atgttttcta gaacttcttc
     1921 cagcttatgt ccctgtccta acaagttacc ggcacgccaa ttgcgagaat gaacacttgt
     1981 acaagtaacg atcaagtccc ccacaccact caaaccgata aatgtcagag gattggcacc
     2041 catcgcgaca ccaagacggc tgatttctgc caatcctcga gtcatgattg ctgcttttgc
     2101 atcatctccg aatcctaatc catggatagc gccggcacca attgcaatga tatttttcag
     2161 tgctgcacca gtttctacgc caatcacatc attatttgta taaatcctga aataatcatt
     2221 catgaacagt ttttgtacat aggctgctgc tttttgatca atacttgcag ctgtaattgt
     2281 tgtgatatca tgtactgcca cttcctcagc atggctagga ccagataata caacaattgc
     2341 ctgtcttttt tcttctggaa tttcttcagc caaaacttct gagattcgtt tatgcgtatc
     2401 ttgttctagt cctttacttg catgtataat gattggctta gtattcattt taccaataag
     2461 ttcctgtgcg actgaacgaa tcgcttttgt tggaacaaca aataaaatag catctgcgtt
     2521 atccactgct tctgccaatt ctttatatcc gataatcgat tctgggatcg tcaaatcagg
     2581 taaaaaatgc tgatttgtat gatacttatt gatttcatca atctgttcag gtacatttcc
     2641 ccaaatacgg acatcatgcc cgttttctgc caatgtttgt gctaaagcag tgccccaaga
     2701 tccaggacca agaactgcga ttttttgttt catggatatt cctccaaata aataattgat
     2761 aatttccatt atagtataca tttcttaaag ttgggactaa tttccattgt ttttaagtgt
     2821 ttgtttactt cttttatcgt ttttacttga aataatcaat gatatgttac aatagtctac
     2881 attttatttt tacactcgtt atgctttgct tgttcctaag aggaagcagt tttgacaatg
     2941 ttactaccag cattactatt aggaggttag gaaacttctc ctagtgagta ttgatttaaa
     3001 atacataaga gacagattga acatttctaa atctgtcagg tcctgcaacg gacagattgt
     3061 ctctgttgac ggttgacata ggaacttttg ttttagtcaa cattctggat acaaaacgct
     3121 atgtaaactg gcgcaactcg ttgtacttgg acttttacta cggatccatg caacaactaa
     3181 atagtactat tgcataacaa aaaatggttg gcacccacat gtcccattaa acagattata
     3241 agttgaactg tagataatgc aaaaaatgtg ttttataacg taattgatgc caatatttta
     3301 aaaaaataaa gggagcagtt atcgctgctc tctttatttt ttatattctt tttatccagt
     3361 ctatcctaat aatcaaactg acgatagtag cggcgtatct ctaatggatg gcagttcaac
     3421 tgctccacat gagcatcgat gcgttgtgtc actacatgca tcaataagaa agacaaaaca
     3481 cgtccgcgat atttttcact gataccttct actggatagt cttttgtgtc tatcaatgta
     3541 taattgctgc aaatttttgg caaaagttta gccacacgtt cagataacac tctctgttca
     3601 tcttcgccta aaaataatgt gactggggtt gtttcttcta cgatctctaa cgtcccgtga
     3661 agaaactcgg cagcatggat agatttcgat ggaagccagc tttgttcttc ccagtaacac
     3721 atggcatatg aataaacagc tccccattga ttccctgctc caataaaata atgcatacta
     3781 tcacgtcgat gtttttctgc aaatgataag ccaaatgcat ctgctttttt ctctgcttcc
     3841 actaaccctg ttggtaaata acgttcgagc tgttcatagt attctgaata agcttcgaat
     3901 tctccattca aatacatcaa tcgatctgct gccataaaaa atttgatttg ttctgttcca
     3961 ggagctggat aagtgaccac aaaatcgcat agctgagaca acttactgtt cgctttatcg
     4021 ataaatccaa tcagtgtcgc tcctactttc ttgatttgtt ctactgcttt cactacttct
     4081 tgagttgtac cggtaacaga ggacaaaata acgatagaat cttttgttaa tcttttgttt
     4141 ccagtagtgt aatattctgc agcatgctgt acaaagacag gcaagttgct tttcccattc
     4201 atataagtga cagcttgcat cgaggaagca tacgttccac cgattcctag ataatagaca
     4261 gcgtcaaatt tttccgcata aagtttatcg atgatttctt ctacttgcgg acgtaaagct
     4321 agtgcgcctt ttattgcttt gatttgttct tcttcattga atttcagcat gatttccacc
     4381 tcttataatt tacttttcaa gactgtatca aagtcttcaa aaatcttttt gttcaagtca
     4441 atacctttag ctactgcggt tttataagcg aatagttgaa acggaacgac aagcgctaat
     4501 acagacagat attcatcaca ttctattgct aatccaagtg ttttctcgtt tcttgctttt
     4561 tttgtggtaa tggtgagagt ctctccaacg taccgactca tatatctttg caacttttgc
     4621 gaacgttcct tatttacact ttccccttca ataaagaata gcaaatgcga agcatctgcc
     4681 tccaggtatg ggccgtgcat ataagcttct aactcaaatc cttgtgacgg aacgcggatt
     4741 gtttcagtca atttcgtctc tgcttcttta gctgttcccc agtttggacc atatccaatg
     4801 gtgacgaaac gctgtgctaa acgaaataaa ctttgatatc catcaaaaaa ttcttccgtt
     4861 ttttgaataa tcgctggtaa atggttgatt attttgcgca actgttgcat gtagtcttgt
     4921 tctatttttt tgctgatttt atttttactt attccaattc ctatccctaa gagtagtaac
     4981 tgtaaaacag tcgcagaata gccttttgta acgaagccta ctgattctac cccggcacct
     5041 aaatcaataa tttgtgcagc ttctaaagca agtggacttt gcacgtcatt tgtgatagca
     5101 acaacaggta acccttgttt ttgtatcatt tttactgctt caacagtaga agcacttttc
     5161 ccgctttgtg acacagcaat cacagtatcg attgaaggag aaagttttcc ataattgaaa
     5221 aaataaaaag gttcttgaat atcgacagta agatcaccat aagattccaa tgctggcttc
     5281 gctgctaaac aagcgttata agatgaaccc gttgctaaga tcagtaaatt cactgttttt
     5341 ttcatatgtt ctcttgtcga aaaatcattc tttttcaaga tcgtacttag tacttccttt
     5401 tcttcataga tataatcttg catcgtaaac attttctctg ctcctttttt aaaaaatccc
     5461 tatccacgaa ccaaaaattc caaagaaagc tagtccgatc aagatcgtta atggtttcac
     5521 ttctttcttc aatagataaa acactatgcc aaatgctcca agacataaga tatttggaac
     5581 gatatcatca aaaatacttt gaacagtcac agcattttct cctgaaccga tttttaaagg
     5641 aatattgatg gtgatcatcg tggcagtcat tgctccaacg accatcagtc caataataga
     5701 cgcgcctaat gtcaaacttt ccatcatacc gtttgcctgg atctttttca aaaaacccgt
     5761 tcctaagcga tatccccaac ctgttgctag atagcgaaac agaatgtgcg gaatattgaa
     5821 aatcaaaatg aacaagatag ggcctaaaat atttccttgc atggctaaag aggtacccac
     5881 acctgtggca atcaatcgca aagttcccca aaagaaagaa tctcctaacc ctgcaagagg
     5941 tcccatcaaa gatgttttga tactatcgat cgcagtcaca tcaaattcag gatcatcctt
     6001 attttcttcc tccattgcag ccgtgattcc taaaatcagt gtaacgatat gtggggtcgt
     6061 gttaaaaaac tctagatgcc gtttcaaagc tgctgccatt tcttctttcg actgatataa
     6121 ctttttcaaa atcggaatca ttgcataaac ataagccata ttcatctgac gttcataatt
     6181 ccaagaaaac tccatttgaa aagaacgcca aaatacgtga tttagctctt ttttcgttat
     6241 tttgctgttt ttgatctcag aattcttcat cttcttctac ctcccctgca gttgtttgaa
     6301 gtggtagttg acggacattc ataatattga ctaccacaac tgctaaaatc gcaccaaaaa
     6361 tagctactcc ggtcacagga atctctaagt aagaagctat agcaaaacct aagaaaaaat
     6421 atggtgcaac ttgtttgttg atcagcaaac gagcaagcat cgcaaaacca agagctggaa
     6481 tcaaccctgt agctactgac aacccctttt gaacgaagtc aggaatcata tttaatagat
     6541 ttccgatcgt attgcttccc accatataag aaaccattac cacaacacca agcatcaagg
     6601 aaagaccgat accggcaagc aagtgcatat gctcgactcc tttataattt ccttcttctg
     6661 cataattgtc tgctttatgg ttcataattg gaatcaaaag ccctaagtaa atatttttca
     6721 atatcaatgt caacgtagca atcggcaaac ctagtaaaag cgcggtttct gtaccggctc
     6781 cagctgtaat agcaaaagcc gtccctaaaa tcccaccggt cacaacatca ggtggaatcg
     6841 aagcacctac tgagaacgat ccgataaatg ctaactctaa agttgcgccc ataatgatcc
     6901 cagtttttac atcacctaac acgattcctg taaacagccc cgtcacaatc ggacgagaaa
     6961 gcaacgatgt ccctagtgca tattctgatt gtgcgacaaa tgcaacaatt cctaataaga
     7021 ctgcttgtac aatcattgag gttcttcctt tcttacaaaa cttctcttac atccactttt
     7081 ttatctgctg gtacttgacg gatttctact tctatttgtt tgtcaattaa tcgtttcaag
     7141 cgttcctcct cttctggtaa aatatttacc gcttttccga tgctgcgagt accaggtttt
     7201 gccttgatcc ctcctaagtt gatggttttg atttctggat acgcttctgc cagcttatat
     7261 gcatcctcga tcgattccac tacgatgaat aacttatatt tatctgtcac cccgcttttc
     7321 aacgcggcaa tcgagtcatc aattgatttg atcactagtt tgactccttg tggcttggct
     7381 aatttgatcg ttgtctttcg tatctcattc gtaggtacat catcattagc aatcaaaata
     7441 cagtctgcgc ctattgtttg tgtccatgaa aaagctactt gtccgtgtaa taaccgatgg
     7501 tcgactcttg tcaatacaat catttttctt cctcctaaaa ttcgtcttct tctattttct
     7561 gattgagccg ctcgttacaa aactggatca ttttttttga atcagttagc acctgctgga
     7621 tcaaaacagt tgtctctact tcagcgtcca accgagatac tagctcaatc aatagtggca
     7681 aattcaatcc ggcaacgaga tagacatgat cccgattgat atattgtaag aattcgttgt
     7741 tgacacttcc gccaaaaaga tccgtcagaa caatgatttc tttatctttg tacctcataa
     7801 aaagctgcct tactgtttcc gctaaatcaa aattctcatc agtatagcaa tcgaatacag
     7861 taatagaatg atttttccca tagatcagct ctaatgaatc taatatccct gaagcaaatt
     7921 ttccatggga agctaagata atttctctat ccactttttc atctcctctt ttcacttaca
     7981 catactaaaa aagcaagttg catgccaaaa ttagtggcaa caacttgctt atgttcaaaa
     8041 ttcttcttct atcgagagaa actctgtatc ttcactcaaa atatcataga tataggcaat
     8101 ctcagaattg gggatcatga cactataatg ctcttcaatg acactaaacg cagatttaat
     8161 agcagataac ccttcttttt gacactgctt ccatttctct aatccttgat aggtttcgat
     8221 tggcatttgt cggatcaatc gttcaatgag acagctcaca tggacataca acgctaattt
     8281 tttgggattg ctgatgcttc gattcaactg cacctctaat tctctcataa aatgatcgat
     8341 ttctcccatc accttctctg tatctagaat agtcacggaa tccagtactt tttccaatga
     8401 aaaattacga atgatgcgct gattgaatat ttccttctct gaagcattca tagtagtgtc
     8461 caaccattca gctagtacag acatcttttc ccccgagatg aggtcttcta atgaaagata
     8521 gtcgatattg gtgatatcag gatctgtggt gccaatcatt cctacgactt cgtatatgga
     8581 aaataatggg tcactgtttt tcttatcttt taattgctga tattcatatg ggatgatttt
     8641 caactgacaa gccgtaggta agcttttttc tagcagttca cttaagtgga ccgccgtacc
     8701 gattccagtg aagcaagtag taatgagtgc tttgggtttg ttttcctctg gatagagcag
     8761 tcgccattct ggctggatct gtcgaacagt ctcttctgct atctcttcta atgatacatt
     8821 tttttgcagg cattccccta ctgtgattgc taaaggtgtc gtcacattat tcaaaatcaa
     8881 aagcggtacg gataactgtt ttttaaaaaa ctgatggatt tctttcagag atcccatgtc
     8941 tactaatatg atcaatccat ttgaaacatc gctgttttcg caataatcaa ggatttctga
     9001 agcaatctgc tgtggtgtga catctagtgg catatcaaat gattcaaata gatcctcttg
     9061 taataaacga tttactacat ttgccatact gctagcagtt gcataaccgt gagcagcaat
     9121 catcgctttt ggcagtcgtt tttcttttga ccatttcgct ttttttagat agatcgtcag
     9181 taaaatccga tccatacttg tgtcttcaat atctaatttg atcttactta attccagaat
     9241 tcgttggaca tagtgataac tagatggata agactgagaa acttgttgtt ctaattcttt
     9301 gattagttgg ataatatcat gttcttccgg taaccatttg atagtgcttc gctgatagag
     9361 atagtaactc aaggcataga cactgtttcc atcgaatttg atttgatagg cagtttccat
     9421 ttgtcgaaag gtctctcgga tagattgtgt ccaataaacc agcagctcgt gtttttcttg
     9481 tctactggtc tcaaacagca aaaaatcaaa taattgaatc acttcttgct ttaattttcc
     9541 ttcgcaagaa tatagcagac agttattttt cttgaaatca attaggattt gctcaaaact
     9601 tttaacgatt cgctgctgtt cgggctgttg cttctccatt aattgctcta aggtctggtc
     9661 ttgcgtaata tagattcctt gctgtgctgt atttttagta ataggctgcg caagtagttc
     9721 tttttgcaaa tgatggatcg tgacatggat ttcaggctgt tcacgctgtt cagcatatgc
     9781 ttttgctgct gaaactttga cgatattttt cagctctcct atgtttccgg ataatttctg
     9841 acttgttaaa agtgacaaag ctggtccact gactgacaaa gggctcccca tttttctttg
     9901 ttcttcgaga aaaaaagagt aaatcagttc tagccgttca ttacgactac gctgattaag
     9961 tgcaggtagt tcgattcgga taggtattct tcgaatgaaa gttgttaaga aatgactagt
    10021 aatctcttca gtcgtagcaa aaaagagacg tgttttgatc cggcgtgaca aattaggttc
    10081 tcccatacga taaatcacac cttgatcaag ataggtgaac agtttttcct gaccttctgg
    10141 tgttaagcga tgtacctcgt ctaaaaacaa gatcccacca tctgctgctt caaaagcccc
    10201 ttttttattt tcttctgcac cagtgtacgc tcccttaaca tgtccaaaca aattgctagt
    10261 caaaagttca ggattatctg catattgtgc acaattaaaa gtgatgaatg gtgcagaatc
    10321 ttctagcaga tcatgaagca gacaatactg atagaccaaa ttaactaaat aacttttacc
    10381 tgtgccactt tcgcctgtaa tcaaaagtgg taatccgcca tctggatagt aaagagctgt
    10441 tttgatttgt tcgatacttt ctttcaaact ggcgtcgtat ccgatcataa aagagaataa
    10501 gtcttttggt tgcgcgaaaa aaggctgttc ctctttgaga tcatcgatag aaaaataaaa
    10561 attcgtgcgt aacttaaaaa attgtttttc aaaagcttct ttgtggaaat aaatcactgg
    10621 tcgagaattg attttgacta gtagttgctc atcatttaac tggttcaaat aatgactgac
    10681 tgtgtttctt tttaccccaa aatgatcagc taacctttgt gctgtaaaga cctcgttcat
    10741 atgttctaaa tcgaaaaagg ctgtctggtt ctctaagtaa cataaaattt ccttcttcaa
    10801 caacttattc acccctcctc catcatagaa aacggattca ttttgtcaat aaaatcttta
    10861 ataaagaatt gaaaaatata tcttattata gacagcagcc tacttatccc ttataatttt
    10921 tattctaaaa aacgtacagt tccttccagt ttttatactg gaatttcaac atatgaaaga
    10981 ataaggaggc tatgactatt caatgaaatc ggataaatat aaaaacagga aacatacttc
    11041 ctggaaaact tttcgagaaa tcatcggatc ttatctcgct gtagttgtat ttttgccttt
    11101 gctttatatg gctatgacag aacaaactcg ttttattggc gtagatacgc aatatatagc
    11161 cgaaacagga tttttattca tctttatctt gatttttgcg ttctataaat ccttccatac
    11221 aaaataagat tcacagattt caactttcct gtctgttttt agctattaca aatccttata
    11281 tgtggtataa caacaattta ttggcataat gaggaaaaac gagttatgat gctttcagag
    11341 agtaaagagg tactgttgtc accatccttt ttattgatta cgtacaccac tcttagtttt
    11401 ttcccattga ttacgaaaac aaggtagaaa cattgatgtt cctaccttgt tttctttttt
    11461 tattttcaga tcaaaatctc aagtggcttt tgacttgatg tcgggaggtt gtcttcgttc
    11521 catcaaacct gatagaatct gcgccaaacc atagttttct ccactattat ttattcctct
    11581 aagatagtac ccacaataaa
//
LOCUS       DAZAOD010000083        11583 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000083 DAZAOD010000000
VERSION     DAZAOD010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.085"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(105..629)
                     /locus_tag="ACHDPO_002203"
     CDS             complement(105..629)
                     /locus_tag="ACHDPO_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFN3369814.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACHDPO_002204"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="ACHDPO_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFN3369815.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACHDPO_002205"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="ACHDPO_002205"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFN3369816.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="ACHDPO_002206"
     CDS             complement(2351..3031)
                     /locus_tag="ACHDPO_002206"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFN3369817.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="ACHDPO_002207"
     CDS             3157..4026
                     /locus_tag="ACHDPO_002207"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFN3369818.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="ACHDPO_002208"
     CDS             4052..4567
                     /locus_tag="ACHDPO_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFN3369819.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="ACHDPO_002209"
     CDS             complement(4614..5177)
                     /locus_tag="ACHDPO_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3369820.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="ACHDPO_002210"
     CDS             complement(5232..5411)
                     /locus_tag="ACHDPO_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369821.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="ACHDPO_002211"
     CDS             complement(5488..5997)
                     /locus_tag="ACHDPO_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369822.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="ACHDPO_002212"
     CDS             complement(6093..6473)
                     /locus_tag="ACHDPO_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFN3369823.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /gene="pnuC"
                     /locus_tag="ACHDPO_002213"
     CDS             6803..7552
                     /gene="pnuC"
                     /locus_tag="ACHDPO_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFN3369824.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="ACHDPO_002214"
     CDS             complement(7736..9013)
                     /locus_tag="ACHDPO_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369825.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="ACHDPO_002215"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="ACHDPO_002215"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFN3369826.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="ACHDPO_002216"
     CDS             complement(9935..10879)
                     /locus_tag="ACHDPO_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFN3369827.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="ACHDPO_002217"
     CDS             complement(10881..11567)
                     /locus_tag="ACHDPO_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFN3369828.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3295 a         2460 c         2042 g         3786 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaataacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taa
//
LOCUS       DAZAOD010000084        11345 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000084 DAZAOD010000000
VERSION     DAZAOD010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.086"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1031)
                     /locus_tag="ACHDPO_002218"
     CDS             complement(<1..1031)
                     /locus_tag="ACHDPO_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3369829.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSVVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="ACHDPO_002219"
     CDS             complement(1113..1802)
                     /locus_tag="ACHDPO_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFN3369830.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="ACHDPO_002220"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="ACHDPO_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFN3369831.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /gene="rplJ"
                     /locus_tag="ACHDPO_002221"
     CDS             complement(2329..2832)
                     /gene="rplJ"
                     /locus_tag="ACHDPO_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFN3369832.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="ACHDPO_002222"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="ACHDPO_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFN3369833.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="ACHDPO_002223"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="ACHDPO_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFN3369834.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="ACHDPO_002224"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="ACHDPO_002224"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFN3369835.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="ACHDPO_002225"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="ACHDPO_002225"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFN3369836.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7544)
                     /locus_tag="ACHDPO_002226"
                     /pseudo
     CDS             complement(6444..7544)
                     /locus_tag="ACHDPO_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7636..8523)
                     /locus_tag="ACHDPO_002227"
     CDS             complement(7636..8523)
                     /locus_tag="ACHDPO_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFN3369837.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="ACHDPO_002228"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="ACHDPO_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFN3369838.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="ACHDPO_002229"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="ACHDPO_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFN3369839.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="ACHDPO_002230"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="ACHDPO_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFN3369840.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /gene="cbpA"
                     /locus_tag="ACHDPO_002231"
     CDS             9754..10398
                     /gene="cbpA"
                     /locus_tag="ACHDPO_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFN3369841.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="ACHDPO_002232"
     CDS             complement(10454..10957)
                     /locus_tag="ACHDPO_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFN3369842.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
BASE COUNT         3312 a         2359 c         2075 g         3599 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactac acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgct
//
LOCUS       DAZAOD010000085        11275 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000085 DAZAOD010000000
VERSION     DAZAOD010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.087"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..564
                     /locus_tag="ACHDPO_002233"
     CDS             1..564
                     /locus_tag="ACHDPO_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369843.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(625..990)
                     /locus_tag="ACHDPO_002234"
     CDS             complement(625..990)
                     /locus_tag="ACHDPO_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFN3369844.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1066..1311)
                     /locus_tag="ACHDPO_002235"
     CDS             complement(1066..1311)
                     /locus_tag="ACHDPO_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3369845.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1381..1635)
                     /locus_tag="ACHDPO_002236"
     CDS             complement(1381..1635)
                     /locus_tag="ACHDPO_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369846.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1799..2122)
                     /locus_tag="ACHDPO_002237"
     CDS             complement(1799..2122)
                     /locus_tag="ACHDPO_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369847.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2309..2382
                     /locus_tag="ACHDPO_002238"
     tRNA            2309..2382
                     /locus_tag="ACHDPO_002238"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2343..2345,aa:Ile,seq:cat)
     gene            complement(2767..3264)
                     /locus_tag="ACHDPO_002239"
     CDS             complement(2767..3264)
                     /locus_tag="ACHDPO_002239"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFN3369848.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3304..4113)
                     /locus_tag="ACHDPO_002240"
     CDS             complement(3304..4113)
                     /locus_tag="ACHDPO_002240"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFN3369849.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4447..5304
                     /locus_tag="ACHDPO_002241"
     CDS             4447..5304
                     /locus_tag="ACHDPO_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFN3369850.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5297..6199
                     /locus_tag="ACHDPO_002242"
     CDS             5297..6199
                     /locus_tag="ACHDPO_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFN3369851.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6232..6582
                     /locus_tag="ACHDPO_002243"
     CDS             6232..6582
                     /locus_tag="ACHDPO_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFN3369852.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            6631..7554
                     /locus_tag="ACHDPO_002244"
     CDS             6631..7554
                     /locus_tag="ACHDPO_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFN3369853.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            7632..8525
                     /locus_tag="ACHDPO_002245"
     CDS             7632..8525
                     /locus_tag="ACHDPO_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFN3369854.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            8563..9126
                     /gene="amaP"
                     /locus_tag="ACHDPO_002246"
     CDS             8563..9126
                     /gene="amaP"
                     /locus_tag="ACHDPO_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFN3369855.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9140..9328
                     /locus_tag="ACHDPO_002247"
     CDS             9140..9328
                     /locus_tag="ACHDPO_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFN3369856.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9341..10243
                     /locus_tag="ACHDPO_002248"
     CDS             9341..10243
                     /locus_tag="ACHDPO_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFN3369857.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10275..10517
                     /locus_tag="ACHDPO_002249"
     CDS             10275..10517
                     /locus_tag="ACHDPO_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFN3369858.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(10773..11144)
                     /locus_tag="ACHDPO_002250"
     CDS             complement(10773..11144)
                     /locus_tag="ACHDPO_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369859.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3994 a         1926 c         2137 g         3218 t
ORIGIN      
        1 gtgttatata ttaaaaaagg cataatagtt ataagctttt ttaaagaata tttagaaatt
       61 attaattttc gtctgaaaac aaaaaaagaa agcgttatta ttttagtcta ttttcagggg
      121 gggaacctta tgataaaaaa actattttta ctatcaatat taacgctagc aatggcaggt
      181 tgttctgact ctggcttagc aactgaactg atcacaaaat caactgaagc cacgacagag
      241 gagttaaaat gtggaaacga tcacagtgac tacagaggct taaatcgacg atgcatggga
      301 atattaggca gaagcaattg taagcatcga tgtagtaatc gaagaaggtg tagaagaagc
      361 aacagaaaaa tcaaaagaaa gatcaaaaga agcaatctgt gctgtgcatc gtatacagac
      421 gtcgaagatg cggtactttt aaaccacgtc aggagatgtt catttatgtc tagggaagtt
      481 ggcgatgaac caaaactaga gtacgctttt agttttgcac gtgaggatga agataaccct
      541 aaaacttacg acattttagc ttgatctaag atggttaaag ctttttaatg aagtaagagg
      601 agatagaagg cttttctagt tatattaggt aagataaatt cctttttgct ccaaatttgc
      661 taaacattct gctagataaa cttcatcgtg ttccggataa atcggcacgt tgcgctctac
      721 agtaggtaaa tcaaaaaatg cttcgcatga tttgccacga tacataggat ttttccactc
      781 tggtgctggg ctgtaaccac gtttttccat ttcatccatg acaagctgat gatattggaa
      841 taatctataa ggagaatagt gaaaaacata atccacagta gcatgtttct ttccccagcc
      901 atttcctctt aatgcacagc attcccgatg ttgtcctaaa agctgttgac gaggaagctt
      961 tgaaatcaat ttttcatgcc ataatcgcat agaaatgtct cctttatata tagattgtta
     1021 accttagacg ttaaatgaaa aaaccagcac caaggctgga aaaaatcact tcagtttgct
     1081 tgctgtttct gagcgaccaa ttaggtaatc aacggaaata tcgtaaaagt cagcgatata
     1141 gattaattca atgatgcttg gaatttcttc tccttcttcg tacttacgat atttgaataa
     1201 aggaatactt aacgcgctag aaacagctac ttgagataaa gatcggccag ttcttaagaa
     1261 attcagacga caacgtaaag tatccagtaa aatagcttct tcgatactca tttaatcacc
     1321 tttcattata gtagaatagt tataatgact atagaaagct acacatgcaa tcaatagtac
     1381 tcaatgtttt ttatttaaac gtatcaaata aagaatgacg atcaataaag acaaaaccag
     1441 tcctgataat tcttctataa aaacactatc gggttcaaag tagttgtaat taaaaacttt
     1501 ccacataaag tagatagccg gaagagtcaa aatagctaaa taaaaccgtt ctttgttcca
     1561 attcataaga taaacaatac ttgcgaccag tgcgaccgca ggcacccaaa acaaaactct
     1621 caccaacgta atcatgtaac ggactcctca acgattcata taataaaaga taacatgtta
     1681 ttgcatacat cacaaatgaa atgctaggaa aataaaagaa gaatagatca atgaaaaatg
     1741 aaaaagcaga acagttttct gctgataagc aggaactgtt ccgctgaatg tgtcttatct
     1801 atcgagaaaa aatcaatgga ttgatatcta agtaattcaa tacatataaa aagaggacga
     1861 tcgcattcac taaaaaggaa agaatgatga tcccatagcg aatggaaaca tatttaacaa
     1921 atacttttgt ttgaatacgg gcatatcttt ttcctttata gctgagcatc atgacaagaa
     1981 gcaaaagggt aatcacacct tgaaaaatca ttccaataaa cagaattcct gaggtttgat
     2041 aatttaattg gagaaaataa gctgctgccg caactaaatc gaataaaatc gcaataaatg
     2101 gcaaaataat cactcctaac attgagaata aataaaagaa taacattttt tctaaaataa
     2161 gcaaataaaa attaaagtaa caaaatagtt atgacacaag taaaagaaat aagaataaca
     2221 atattatttt acttatattt tgaaacttgt gagagtttgt cattcgtgct atagttgaaa
     2281 agtaacaaaa ataaatttta tttatgatgt acctttagct cagttggtta gagcagacgg
     2341 ctcataaccg tccggtcgta ggttcgagtc ctacaaggta cataagaggt tgtgaaaaag
     2401 ctgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg tttttacttg
     2461 gctgttctta ttactgcaga tgcaagcttt tgaataccgt ttaaggaaga ggttgtgaaa
     2521 tcagcgtttt gacctgagta ttagcttaac aaacggaaaa atagttcctc atattttgcc
     2581 gtttgttaag ctaataccga gggtcagctg attgaacacc atttaagaaa gaggtcgtga
     2641 gcctgccgtt tcactctgtg tcataaaaaa gccaatctac tttgatagaa aaagcacgta
     2701 ggactaaaac agttctgcgt gcttttttta ttgtgtgtta aatatcgtaa atgaagatag
     2761 atatttttat gattcgacga tagagacgtt gaaatctttc aacagctcta aagcggattc
     2821 tccgtgtttt ctactggaga ctaacattgg atcaacaaaa aagtctgctt caggaaaagc
     2881 actctgcagg cctatcagat tagagagtac acacaagttt gtttcaatcc cgactacttc
     2941 gatctctttt tgttcttctt tgctttcaaa taaagtttcc tggatttcag ctaaagtttc
     3001 aggtggaatc gtaaagtaat actttttaat cactcgttca ttttcttgtg gagaaagaag
     3061 agggatcaat tgcaaatctt ctcgttcttc ttctttgtcc ttcagttcaa ctggtatatc
     3121 ccgtgtgaag agaatatatt cattattttg gcgtgcttta gctaatcttt gagcaatacg
     3181 ttctgccaat tgatctgact ctggaatata aaattcgctg tttggatcaa gaatatgatt
     3241 ttgcatatca ataataacta acattttctt tcctcctaca ttcatatcgt cattttattc
     3301 tttttaatag aagtttttta aaatataagc aacaccagct tcttcattcg tcagtgttac
     3361 ttggtttgca atttctttta cttgtcgctg tgcattcccc atcgcaatac tcaacccgct
     3421 gtaattcaac atagcaatgt cgttttcttg atcgccaaaa gccatgatgt cactcgattc
     3481 gattccaagg taatccgcca gaaaaacaag tgaatgagct ttagtgatac ctgtaggcgt
     3541 gatttctaag aaatgcggat cagagaatac tgattggata ccatctgctt gcagatctct
     3601 ttgtagcttc tgtagttttt cttcactctt atctgttaat gctaatttaa gatagctaag
     3661 agaaggatct tccaacatat ttaaaatttg atcaaaagaa tggttctgta aattgaaatg
     3721 ttcataataa gggtcatctt tgactagatt tgattcatcg aatgtcagct gatcatcttg
     3781 ggtttctcgg ctagcaatga tggatatttt cgcttcttga gcatagaaga aggcttttct
     3841 cagtgtatcg ctatctattt ttgaacgtct gagaactttc gccatttttc catccttcat
     3901 ttcagcaatc agtgaaccat tggaagaaat caaatagcca ccgattccta attcggaaaa
     3961 aatatcttta gcagaaatgc tgttccttcc ggtagcgacg gttacgattc cgccattttc
     4021 atcaaatttc cgaagtgctt ggatattttc ttctggtatc tttccatttc gatcaagcaa
     4081 ggtaccgtct aaatcaatcg ctgctagttt cattttatct tcctactttc tttttacata
     4141 tctattttcc tgttacctta agattaaatg agaatttaaa aaaatgaaac taacttgctt
     4201 tgtcattatg aattttttca aaaaacattc ttaagaaaaa ggtggctata tatagtagtt
     4261 tttggtcaat acctttgaat aaaaagccat gaaaaacgaa tagttagcgc ttaccgatgc
     4321 gttttgtgat aaaaaaattt taaaatattc aatgaaaaca aagcatatat tttgctttaa
     4381 aaccaaatga ggaatattct agatgtagaa caggttagaa aaagattaga aaaaggagtg
     4441 attttgatgg agaagagata cggcgtagtt cctgtggtaa ctgcttcaga cgaaaattat
     4501 gctccttact tgagcgtgat gatcgcaact gcattagaaa attgcaataa aacaagacgc
     4561 ataaaatttt atgtgattga cgatggtcta tcagaatata gtaaagaagg attggaagaa
     4621 acggtaaata aatattcaag taatgcaagt atccaattcc tgacagtgga aaaagatatc
     4681 tacgaagact tcctagtcag tgaccatatc acaactaccg cttacttaag aatttcttta
     4741 ccaaacttat tagctaaaga ggattataag aaagtccttt acttagattc agatgtgtta
     4801 gtactagacg atatcgtaaa actatatgat gagccgttaa atggaaaaac aatcggcgct
     4861 attatcgatc caggccaagt gaaagctttg gaaagattag gaatcgattc cgatgacttg
     4921 tacttcaatt caggagtgat ggtgattgac attgatcaat ggaataaaaa agaaattaca
     4981 gaaaaaacta tccattacct cagtgaaaat ggcgatcgaa tcatctatca cgaccaagat
     5041 gctttgaatg ctgtacttta tgaagattgg gaacaacttc atccaaaatg gaacatgcag
     5101 acttcgctga tttttgaacg tcatccagca ccaaatgaaa aatatgaacg tcagtataaa
     5161 gaaggaaatg aaaaaccttc gatcgttcac tttacaggac atgataaacc ttggaatacg
     5221 ttgaaagatc atccgtatac caatttatac ttaaaaaaat tagcacacag tactctaacg
     5281 aaagtaggcg agatcaatga ataaaaaaga aatagcagta gtcgcaagtt gtaacacaaa
     5341 attcgtacca catttagctg cattatttgt ctcagtatta gataattgca acccgtctaa
     5401 atttgttcgg ttctatgtga ttgacgatga tatcgatttt gaaagtaaac agcttttacg
     5461 cttctcagtg aaaaacgcac gaatgaactc agatgtggaa ttcttgaaaa tcaataaaga
     5521 attctttaca aatgtggtaa tcagcgatcg tattccagaa acagcttatt atcgtattgc
     5581 gattccggaa ttgttccgcg gcacagaagt tgaacgtatc ttatatatgg attgcgacat
     5641 gatcgcttta caagatatct ctaaattatg gcgtcttgac ttcggtgatt caatcgtagc
     5701 agctgttgaa gacgctgggt tccatcaacg actggaaaaa atgaaaattt cagctaaatc
     5761 aatgcgttat ttcaactcag gtttgatgct gatcaatgtg aaaaaatggt tagatgaaaa
     5821 tattacgcaa aaagtattag atttcatcga acataatcca gaaaaattac gattccatga
     5881 ccaagatgca ttaaatgcta tcttacatga ccgttggtta ccacttcatc cgcgttggaa
     5941 tgcacaaggc tatatcatgg caaaagcaaa aaaacatcca acagcagcag gtgaacgtga
     6001 atacgaagaa actcgcaaca atccttacat tatccatttt tcaggacatg tgaaaccgtg
     6061 gagcaaggat tttgaagggc caacgaagaa atattacgaa aaatatgcag ggatgacggc
     6121 tttccgttgt gtagctaaat tccctaaata tccaaaatat gcaaaagttc aaccaaaaac
     6181 agatgtagtt gttaaataat agaagaccac aactgaagag ggggagtagg aatggaaatt
     6241 acaatgtcta aaaatgcagt agagacgtta attgaaaagg ttggggaaaa tacaaaaatc
     6301 gcactcgcgc ttatcaatga ttccgatcca tttctaaggg acaaaggtgc ttttgcaaaa
     6361 ggcagctttt ttcaaatcat tccttttgtt tcggaatttg gagaatatgc gactaaaatc
     6421 gagcatccat tattggacat ctatacatct aaattagagc aaaattattt cggtaaacga
     6481 ttgaacatgg acttcaacaa acagcttgac agcttttcat tagaaaatga aatcgcagta
     6541 ctcgattata atatcaaatt aaagaactgc ttcttcagct aatagtttcg agaaagtcca
     6601 aaaaggaggt atacattgag atactacttt gtggatgaag aaaagaatgt aatagaaaca
     6661 gatgaaaaaa aatataattg gctcgtactt gatagtgcaa agcccgaaga gattgagcaa
     6721 gcaatcgaag aattcgagct tcctgatgat attttcgtag gaaccgaata tccggaagaa
     6781 gtttctcgga tggagcgcct ttatgagacg aaactagagc atccattttc tttggtagtg
     6841 attaatctag atcagtcaga taatcgtatc gaaaaaaaat taacgccaat atcttttgta
     6901 ctttccgata atctcttgat tacttgtatc gatagaaaaa ccgaatttgt ggatcggctg
     6961 ctgacaaagc atggaaatca tttaaactcg tttgaaaaga tcatcacgta tacattatta
     7021 gatatttaca cccattacgt gaaagaacta agagagatga aaaagcgaat tgacgctttg
     7081 gataaagcag ctcgtaaaac aacggaaaat gaagaactgt ataaacaggc agatcttgaa
     7141 agagacatcg tatatatcga tcatacctta agagatcaac gggaaacaat ggatcaatta
     7201 tggaattctg aaactttcat caaacgttta gacgatgaac agctactcta tgatgtccat
     7261 ttgagacagc gacaaacaga aaaaatgatc gagatctatc gagatttatt agagagtatt
     7321 ggtgatctat tcaacgggat gatggacaat aatctaaatc atatcatgaa atatctagat
     7381 tcagctgcat taatcatttc cgttccggcg ttgttcgcag ggatttgggg aatgaataca
     7441 ggaggattac cgggtaaaag ttctgctcta ggctttatac tcgtagtctt tggctctttg
     7501 atagcagcag tagttttagg ttaccattta taccggaaag attatacaaa ttaaagaatc
     7561 tatttaaaac aggtatcaaa caaagaaatt tgttttggca atacaattta aaaactagga
     7621 ggaatacagc aatgacagaa ccaaaattaa tcgacccgcg aaacttgtac catacggaga
     7681 aatttcctaa acaagatcag gatacaccag ctttacagca gaatatgatt cctgttcctg
     7741 attgtggaga agaatcctat gaaggcaata atcaactaga aaaccgccgt gtactaatca
     7801 ctggtggaga ttcagggatc ggtcgtgcag cagcgattgc atttgctaga gaaggggcag
     7861 atatcgctct tcaattcttc ccaggagaag aaaaagatgc agaggaagta gcaaaatacg
     7921 tgaaagatgc aggacgtaag attgtcttac taccttttga tcttcgtgac gaacaagcac
     7981 ctaaagaaat catagataaa gccgtgagtg aacttggcgg gctagatacg atggtactaa
     8041 acgcaggaca gcaaatttct tgtcagtcta ttgctgagtt accacttgag caagtcaaag
     8101 acacatttat gataaacatc atcgctatgt ttgctttagt gaaagaagct gttccgcata
     8161 tcccagcagg aggagcaatc gtaacaacaa cttctgttca agcattcaat ccaagcgaac
     8221 atttattaga ttacgcagca acaaaagctt caatcgctaa ctttacgatc ggtttagcaa
     8281 aacagcttgc acctaaagga atccgtgtaa atggtgtagc acctggtcca atttggacac
     8341 cattacaact agacgaagga caaccttctg attcgatccc tgaatttggt cagcaaagtt
     8401 tactagaacg tgcaggtcag ccaggagaat tagcaccagt ttatgttttc ttagcatcga
     8461 ataaagcaag ttatgttaca gcccaaattt acggagtaac tggtggagaa gcgatcaact
     8521 tataagaagt tgatcgtttc acccctatga ggaggtgcga aaatgaataa aggtgtaaaa
     8581 acgatcggag tgatcggaac attacttttg ctatctgtgc ttttgtttgc gatactatta
     8641 agtgcaacct atccattgcc ttttcagcta gagaagtttc gattcttttc catcactaat
     8701 tcatacgtgc aacaatatgt attttggctt gccgttgcat ttgctatttt gacaattatc
     8761 acgttacttg ttttcctgtt ttatccaaaa acaatcggaa actttctact gaaacatggt
     8821 gatggggagt tgacgttgga taaaaaagca attgaaggaa tggttcgttc tcacttgcat
     8881 gaagatgaat tcatccattc accaaaagta aatgtcaaag caacgaaaaa caagatcgcc
     8941 gtcaatgtaa aaggggagtt gaaacgaact tcagcactca ttggtaaaac aggaacattg
     9001 atgaaagaaa tcgaaaatga agtacaacac atattgggaa caaaagagcc agtgaaagta
     9061 tcggtgaaat acacaggctt tgaagaacca gctaaacgaa gcaatgaccg caaacgagta
     9121 gaataggggg ggaccaaaaa tgaaagaact attttcgaca tacaagctcc ctatcatctt
     9181 tggggtactt ggattgatat tagccgtttt atggatcacc gtgggctttt tcaagacctt
     9241 attgatcttg atcatggcag cgatcggcgt cgctatcggt ttttatctga aacaaacgaa
     9301 aatcttagat cactatttta aatcttagga ggaaacatcc atgaataaca ataacaaaaa
     9361 taataacaat aaaatgaaca accaaaaacc agtgtctgca catccagacc caacgacacc
     9421 aaaccaatca aatggtgtga acgatgaaaa gaacaaaaca gcaccagtat ctgcacatcc
     9481 agatccagta gtccctaacg ttcaacaagg agtagaagag aagaaacatg atgcagaaaa
     9541 gcatgcacct catcatccag gaactccaga atctaaagtt ccagaacaac atgatgcaat
     9601 cgatccttct aaacctgtgg aagagcaaaa acatccttct gaccatgcga aagcacaaga
     9661 aaaacttagt tctgaccaca caaacggaca aggaaaactt ggttctgatc atacaaataa
     9721 ccaaggaaag catgattctg aacaggaaga ttcaatgcgc ggtgagctga attatgaaga
     9781 taaagttgtg caaaaaatca tcggaatcgc aattgaacaa gtagacggtt tattatctgc
     9841 aaacggtggt ttcttctcta atgtggcagg aaaacttgtg aatacagata atgtaacggc
     9901 tgggatcgaa acagaagtcg gtaaaaaaca agtagcagtt gatatggatg tcattgtgga
     9961 atatggcaaa gatatcgaaa aaatctttga agaaatgcaa gaagtaatcg gcaaagaagt
    10021 aaaaaatatg acacatttag aagtgatcga agtcaacgct aacgtagtgg acatcaaaac
    10081 aaaagaagaa tttgaaaaag atcaagaaac ggtgcaagac aaagtaactg acgcagcgaa
    10141 aaaaaccggt gaatttgctt cgaatcaaac agataaagta aaatcagcag ctggaagcgg
    10201 cgcacaaaaa gtaaaagaaa atacagaacc acgggttcag taataaggaa gtaaaacatt
    10261 aggaggaacg aaacatggga tttatttggt cacttatcgt cggaggaatt atcggagcaa
    10321 ttgcaggagc aatcacgaat aaaggttctt cgatggggat tattgcaaat gtcgtagcag
    10381 gtttagttgg atcagcactt ggtcaagcat tattaggttc ttggggacca agtattgcag
    10441 gaatggcaat cgtgccatca ttgattggtg ccatcatttt agtactaatc gtatcattct
    10501 ttgctcgaaa actgtaaaaa gacttttaaa aagaggtcgt gaaaaagctg ttcttcatca
    10561 agtaataaga acagccaaac aaaaatagct tctcatattt ttcatttggt tgggcatatt
    10621 atcgaagatg caagcttttg aacactgttt atacggaata agaggctgtg acaagacttt
    10681 tgtcacagcc tcttatttat gcgggcaaat tcccaattag atttttaaaa gtttttcctt
    10741 aaatgtgtct ttattgatac agagaagctt ctttaataaa acaatgcctc cctaaatttt
    10801 cttgagatag gaaaggtgaa catacaaaat aatacgacca ctttgaaaac ccagatgatc
    10861 cacaaatgga tcgtatgata ctgatgaagt aaaaagcaat ggatcagaaa ctcaaagaga
    10921 ttgaaaaaga caaggaagaa ataatatctc ttttttactc ttgtctgttt tagccaataa
    10981 tagctcgtaa agtaatctag acaaacaaat agaagtaaac aaagtttcgt aagagcagca
    11041 atcgtatcat gttgctctgc tagacgattg acgagcagga aaaatgttgg taatggaata
    11101 tagatcacga gtaatgaaag aaaaaagtaa acaataaatg gcatactatt cctcctaatt
    11161 gtgtgagttc gccctcattt taaaataacg atatttgttt gtgaagcttt ttcgtgtcgt
    11221 aacaaatgtt atctaatgta tttttaaata aataatcatt attatcaaaa taatg
//
LOCUS       DAZAOD010000086        11255 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000086 DAZAOD010000000
VERSION     DAZAOD010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.088"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACHDPO_002251"
     CDS             6..305
                     /locus_tag="ACHDPO_002251"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3369860.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACHDPO_002252"
     CDS             378..1739
                     /locus_tag="ACHDPO_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFN3369861.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACHDPO_002253"
     CDS             1761..2021
                     /locus_tag="ACHDPO_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369862.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACHDPO_002254"
     CDS             2035..2787
                     /locus_tag="ACHDPO_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFN3369863.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGKKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACHDPO_002255"
     CDS             complement(2881..3486)
                     /locus_tag="ACHDPO_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFN3369864.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACHDPO_002256"
     CDS             complement(3539..4513)
                     /locus_tag="ACHDPO_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFN3369865.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACHDPO_002257"
     CDS             complement(4891..5610)
                     /locus_tag="ACHDPO_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3369866.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACHDPO_002258"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACHDPO_002258"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFN3369867.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACHDPO_002259"
     CDS             7161..8558
                     /locus_tag="ACHDPO_002259"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFN3369868.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACHDPO_002260"
     CDS             8639..9079
                     /locus_tag="ACHDPO_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFN3369869.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACHDPO_002261"
     CDS             9227..9553
                     /locus_tag="ACHDPO_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFN3369870.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACHDPO_002262"
     CDS             9554..10303
                     /locus_tag="ACHDPO_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFN3369871.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACHDPO_002263"
     CDS             complement(10383..10838)
                     /locus_tag="ACHDPO_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFN3369872.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
BASE COUNT         3574 a         1963 c         2304 g         3414 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtaaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaac
//
LOCUS       DAZAOD010000087        11247 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000087 DAZAOD010000000
VERSION     DAZAOD010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.089"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1256
                     /locus_tag="ACHDPO_002264"
     CDS             <1..1256
                     /locus_tag="ACHDPO_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369873.1"
                     /translation="VFKHGIALSELTQFLYGQSYFLKFLSYYFNGIFTSTELADLEFI
                     SLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNWEGYENKNPYVE
                     EACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEEDKKSAETKPLF
                     QLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEVVYKNFVLNDLS
                     LNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYLLSEKEQLLYGK
                     IVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFVVSESSVKQFFY
                     RTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQNGLETEKTKIYP
                     ISLKGANIHLYHIAQELHLLKKHIS"
     gene            1477..3240
                     /locus_tag="ACHDPO_002265"
     CDS             1477..3240
                     /locus_tag="ACHDPO_002265"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFN3369874.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            3324..3782
                     /locus_tag="ACHDPO_002266"
     CDS             3324..3782
                     /locus_tag="ACHDPO_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFN3369875.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            3891..4574
                     /locus_tag="ACHDPO_002267"
     CDS             3891..4574
                     /locus_tag="ACHDPO_002267"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFN3369876.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            4721..5335
                     /locus_tag="ACHDPO_002268"
     CDS             4721..5335
                     /locus_tag="ACHDPO_002268"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFN3369877.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            5351..5557
                     /locus_tag="ACHDPO_002269"
     CDS             5351..5557
                     /locus_tag="ACHDPO_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369878.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     regulatory      5782..5948
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            6096..6653
                     /locus_tag="ACHDPO_002270"
                     /pseudo
     CDS             6096..6653
                     /locus_tag="ACHDPO_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            6711..8750
                     /locus_tag="ACHDPO_002271"
     CDS             6711..8750
                     /locus_tag="ACHDPO_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFN3369879.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGEKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKDDDDSANKRASELLQYLNQNYQ"
     gene            complement(8859..10010)
                     /locus_tag="ACHDPO_002272"
     CDS             complement(8859..10010)
                     /locus_tag="ACHDPO_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFN3369880.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(10164..10694)
                     /locus_tag="ACHDPO_002273"
     CDS             complement(10164..10694)
                     /locus_tag="ACHDPO_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFN3369881.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(10793..11143)
                     /locus_tag="ACHDPO_002274"
     CDS             complement(10793..11143)
                     /locus_tag="ACHDPO_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFN3369882.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
BASE COUNT         4045 a         1906 c         2189 g         3107 t
ORIGIN      
        1 tcgtattcaa acatggtatt gctctttctg agctcacaca gtttctgtac ggtcaatctt
       61 attttttaaa gtttttaagt tattatttta atggtatatt cacgagtaca gaactggctg
      121 atcttgaatt tatttctttg agcaaagtat atacaatcaa aaaaatcgta ttggattttt
      181 ttaaagaaaa tgattatttg aaaaataaag aaatcattat cccagaattt gactcgcgga
      241 acatcttgct agctttagta cgttatgtca attgggaagg ctatgaaaat aaaaatccgt
      301 atgtagaaga agcttgtaac gagttgattg attatgtaga gactcatttt tttaaaagaa
      361 gatattcgga agatgaaaag tcctttatca tacgaggaat agagatcgca atcggaagaa
      421 aggcatttcc ccttggactg aaagaagaag ataagaaaag cgcagaaacg aagccgttat
      481 ttcaattagt ctgtcaagga ttggaagagc aaaaaggaat tctagactta caagaagaag
      541 atgtctatta tattttttct ttgttcaaca gtagaaatta taccaatgag aacatggagc
      601 tgttaagaaa agatttcgaa gttgtttata aaaattttgt tctcaatgac ctatcactga
      661 atgaattgat tttacagatt attagtatcg ctgaaatcga cgatgcagaa aattttattt
      721 tcaagcaatc ctttttacaa tttgtccgta cgttgtgggc agatggacaa gtatttttac
      781 cggaaaggat ctatcttcta tcagaaaaag aacaacttct gtacggaaaa attgtagaaa
      841 tattggaaga gtggaaaaag aaaaatcaaa tccaactaag atggaatgaa aatttcattc
      901 gaaaattcgt caaaagtctt tctttgatca acagtgaaca agcggggaga caggaaatag
      961 aaatttttgt tgtttcagaa agttcagtca aacaattttt ttatcgaacc caatttcatt
     1021 tgtatgcgga agaaggcatc gctgaaataa atcctatttt atttcgttca ttagaagaat
     1081 tgcctgatga atgtctatgt gcgaaaaaaa gagtggtttt gtgcgatgct gctagctatc
     1141 aaaatggatt agaaactgaa aagacaaaga tctatccaat ctcattaaaa ggtgcaaaca
     1201 tccatttgta tcatattgct caggaacttc acctattaaa aaaacatatt tcttgatgag
     1261 accttaatta ggagaccttc tacaaagctt tttaattgtc tgtagaaggt ttttatttga
     1321 gtcctgattc gtgcgaagat ctacttatat aacaagcttt ctctgaaatt tttttaaaat
     1381 gctattgact tagagtcaac tctaagtagt agaatagata aagtgtaaca aatctatttt
     1441 cattaaaaga agatagtacg gaggagagaa tgtattatga gtacagtatt acatgtattg
     1501 gatgcaatca atagccccgc agatgtcaaa aaattatctg ttgaggaaat gaaacagttg
     1561 gcagaagaga tgcgccaaaa aatcttgcaa aaggacagcg atgtaggtgg gcacgttggt
     1621 ccgaatctag gtgtagtaga attaacgatt gcgtttcatt atgtatttga ttcaccaaag
     1681 gataaaatcg tttgggatgt ttcccatcag tcttatggtc ataagctttt aactggtcga
     1741 aaaaatggtt ttgaaaaagg acattaccgt gaagtgagcg gatattccaa ccaacatgaa
     1801 agtaaacatg actattttac agtggggcac acatctacat ctatcagctt agcaacaggt
     1861 ttagctaaag cgagagatct gaagaaagaa tcaggaaatg tggtagcatt tatcggtgac
     1921 ggctccctaa gtggtggctt agcttttgaa ggattgaaca atggtggtgt tttacaatcc
     1981 aatctaatcg tattagtaaa cgataatgag atgtctattg atgagaatca tggcagttta
     2041 tataaaaact tagctgagct tcgtcaaacc aacggtaaaa gcagcaataa cctatttaaa
     2101 gcaatgggat ttgattatcg ttacgtggat aatggaaacg atctggaaac ggtgatccgt
     2161 ttatttgaag aagtaaaaga tattgatcat ccgattgtac ttcacgtcca tacggaaaaa
     2221 ggtcgcggtt atcagccggc aatcgataat aaaatgaaat atcattggca tgtaccattt
     2281 gatctgtcca ccggggaggc aaagcaagta acttctggag aaacatttaa tatgatcatc
     2341 atggattatt tggataagaa aatgcaaaca agtacagctc ctattgccgc agtcaatgca
     2401 gcgataccag gcgcctttgg actgaaaaca ttccaagaaa aacatccaga tcattatttt
     2461 gacgtgggga tcgctgaaca gcactctatc actttcgctt ctgctttggc ttctcaggga
     2521 gtacgtccag tcgtcttcca atcaagtact ttcttgcaac gggcatatga tcaattatca
     2581 catgatttag cgatcaacga gaatccagtg attattttag tcggtggcgg aacgatctca
     2641 gctagtgacc gaacacacca aggaacattt gacattcctt acttatcaag tatcccgaac
     2701 atcaaatatc ttgctccagc aacaaaagag gatatgatct ctatgctaga ttgggcgttc
     2761 gaacaaacag cgcagcctgt agcaatccga attcctacac atggtgtaga acatggtaca
     2821 gctatcgcaa atgattatag tattccagcc tatcaaacag taaataatgg aggaaaagta
     2881 gcaattttag ctttaggcgg ttttcttgaa ttaggaaaag aaacagtaaa agcttttaga
     2941 aaaaaaggaa tcgaagcaac gttgatcaat ccaggaacga tcacagaaaa tgacgtagaa
     3001 acattagata aattaaaaga aacacacgaa ttagtcatca cattagaaga tggtagtttg
     3061 tcaggaggat ttggcgaaaa tatcagtcgt tattatggtg attcttcaat gaacgtatta
     3121 aattttggtg cagagaaaga attcacggat agcgttcctg tagggcagct ttatgaacgt
     3181 tatcatttaa caccaaaaca aatcgttgaa gatagtctgc gtgtcttgaa tattcaataa
     3241 ttcattatgc tcaccatcca gataattgtt tatactagta tctggatggt tttttcatta
     3301 taaaaagcaa aggggtggat gttatgtatc agcaagtaga agaatatgtc aaaaagttcc
     3361 aagaaaaata tcctagttat caatcagaaa aattaggttt cttttcattt ggggatacag
     3421 aaaaaatggc agacgagttg agcgaactag ttgtaaaaaa gataaagact ggtacatcaa
     3481 gtggttacga tctgtataaa caagagaatg agcctttacc aaaagttggt caattagacg
     3541 tggtcctgaa tggaaaaaat gaaccagttt gtatcatcaa aaatataaat gtgaccatct
     3601 tgccttttag tgaagtcacg aaagagcatg cttggaaaga aggagaaggg gatcggacat
     3661 tagcttattg gcggaaagtc catgctgagt tttttaaaca tgcttataaa gaagcgttga
     3721 acatagaatt tacagaagag aagctggtcg tatacgaaga atttgaagta attttctttt
     3781 agtaagaaag gtctgctgaa agaaatagct cattattgtc tcctgaatag aaaagggtta
     3841 catttttata tgaagctgta tttttatata acattactgg aggagatatt gtggatacac
     3901 tggaacaaat caaaggcgga gtcgtcgttt cttgtcaagc tttggaaaac gagccgctac
     3961 acagttcttt tattatgggg agaatggctt tggctgcaaa agaaggcgga gcagttggta
     4021 ttcgagcaaa tacgacagaa gatatcaatg aaatcaagcg aatcgttgat ttaccggtaa
     4081 tagggattat caaaagagat tacgatgggt cagaagtgtt tattactgcg acagaaaaag
     4141 aagtggaaga acttttggag acgcaagcag aaatcattgc actggatgca acttctcgta
     4201 aacgtccgac agaaaaaaca actgctgaac ttgtccaaat gattcacgaa cacggtcggt
     4261 tagctatggc agatatttcg acttttgagg aagcgcttca agcgcaagaa gatggttttg
     4321 atcttttgtc tacgacttta gcaggctata cagaatattc acgaaagacg cagacacctg
     4381 attttgattt attgaatcaa atcatagaac aagtcgatat cccagtaatt atggaaggac
     4441 atactgactc tcctgaacaa gtagagaaag catatgaatt aggtgctttt tcagtcgtag
     4501 ttggatctat tatcacccgt ccgcaattga tcactaaaag atatgtcgaa gccgcaagta
     4561 aagcaaataa ctaaaaaaca cgcacggcac agattcttga caaaaaagaa aaattgatag
     4621 atagtttaaa gcagattcta agaagatgaa aaaagcatta cttttcattt tgtcttcaag
     4681 atctgctttt taacgaattt tatagaaaga aggcgaaacc atgtttgaac ggagtccttc
     4741 agaattgaca gaacgtgaaa attacaagtt gctgattggt tcagtcatcc ctagaccagt
     4801 agcagtagta acgactaaat cagcaaaaga tatagtgaat atcgcaccct tcagttactt
     4861 caatatcgtc agttcgaatc gacccatctt atccttggcg atccagagaa aacaagatgc
     4921 agtaaaagac acagcaaaga atattcttga gacaagagaa gctgttatcc atatccttga
     4981 tgaggacaac gtagaagaag taaataaaac agcagccaat ctgcctaatg aggaaagcga
     5041 actgtacctg actgacttga ctttaactga ttcagtaatc atttcagtac cagcattgac
     5101 agaagcaaaa gttcgttttg aaacatcctt atatgaacat gtcgagatac ggaataaaaa
     5161 taaagtaaca gctgatttat ttttgctaga agtacagaaa tatcatttaa atgaaacagt
     5221 ctatgatgat aagacaggaa ggatcgatcc aagaaaattg aatgctgtaa gccgtttggc
     5281 aggaaatgat tatgcagcaa taggagaaat tttcacgatt gcacgtcccg aataaaaagg
     5341 agcactagtt atgttaaaaa taagctataa accatcgaca gattcaaaag aaatgaaaaa
     5401 agaatatgaa acagtgaatg attttctgca agggcagtac ttagaagttc cgccattgca
     5461 agaccatttt gtcgttacta ctgttacttt agatggtaag gaaatagaaa tgccagatca
     5521 aacgattagc ggattgttta attactttaa caaataaata tttattccga aaagtgaaaa
     5581 aacatataaa aaaacacata aaactaaaaa attatcaaag aatcctggtg caactgaaag
     5641 aatttgcaac gggattcttt caacttattt gttatttttt tctaaaaaat attaaagatt
     5701 gttaaatttc actatttcat ttcaaattcc attgcctaat cattaggaaa agtctatcat
     5761 gaactcgtaa atagaatata gtaataacct tgttaggtga ggctcctata caaacatagg
     5821 ctgttgccca gaaacgtcga aagtcgccaa tgggtaaaac agaaactgtt ggattaaggc
     5881 tttttccaat agctaagaat gttttcttta cgttgtatag tgctaaaact cggacgatga
     5941 gatgatgcta ggtcagaatt cttgttcgaa aaggtttctg accttttctt tatatttttg
     6001 tgactgactt atttgatgag acaaactcgc tcctcacctg acaagtggat tgctgtgtga
     6061 ggaggagatg cggtgaaaaa agatcgattg gtggaggtcg ctcggattca cttctggttg
     6121 cacaatacaa ccagaaaaca caacaagcaa aactgatctc tatcatgaga gattcatatg
     6181 tcgatattcc aggttacgga atgaataaga taaatgcagc ttactcttat gggggagttg
     6241 atttattaaa tcaaacatta aaggaaaatt tcaaatttga agctccctat tatgcaagta
     6301 tcacatttca agattttatc gattgcgtta atgaactgtt tcctggtgga gtcaagatcg
     6361 atgcagaaaa atctctagat ttagatggcg tatatataaa caaaggagag caagtgatgg
     6421 atggtaatac tttactccag tatgctcgat ttcgggaaga caaagaagga gacttcggga
     6481 ggatcagaag gcagcagcaa gtgatcaaag ctatctctca gcagctgaaa gacgtaactt
     6541 caatattcaa gctacccaaa gcggttggga aattacttgg tagtatccaa acgaaccttc
     6601 cagaaagtgt gcttctggat tgtggtatgg atttcctcaa agacatatgt tagaataaac
     6661 aggtataaat agtgaaataa aggaatgaca agcaagagaa ggaggaaaaa atgaaaagaa
     6721 gtgacaagca cggcaaaaat cgaacaggcg cttatattgc cggcgcagtg atcttaatag
     6781 cagctgcggg tggcggttat ttttactacc agcactatca agaaacccaa gcagtagaag
     6841 ctggagaaaa gacagttgag caatttgtcc aagctttgaa caagggagat tataacaaag
     6901 ctgcagaaat gacatcaaaa aaggcggcaa ataaaagtgc attatctgaa aaagagatct
     6961 tagatcaata ccagaatata tacggtgctg ctgatgtcaa aggacttcag atatcgaatc
     7021 taaaagtaga taaaaaagac gattctactt acagtttttc atataaagca aagatgaata
     7081 cctcattagg tgaattgaaa gatctttctt ataaaggaac attagacaga aatgatggtc
     7141 aaaccacgat caactggcaa cccaacttgg tttttccaga aatggaagga aatgacaaag
     7201 taagcctgac cacacaagaa gcagcaagag ggaatattat agatcgaaat ggtgaaccat
     7261 tagcaacaac aggcaaacta aaacaattag gagtcgttcc aagtaaactt ggagatggag
     7321 gcgaaaaaac agccaatatc aaagcgattg cttcctcctt cgacttaaca gaagatgcta
     7381 tcaatcaggc gatttcacaa agctgggtac aacccgatta ctttgtccca ttgaaaatca
     7441 ttgatggagc aacgccagaa cttccagctg gagctaccat tcaagaagta gacggcagat
     7501 attatccttt gggtgaagca gctgctcagc tgattggtta cgtgggagat atcacagcag
     7561 aagatattga taagaatcca gaattaagca gtaatggaaa aatcggtcgc tcaggtttgg
     7621 agatggcttt tgataaggat cttcgtggga caacaggtga gaaattaagc attacagatg
     7681 cagacggtgt agagaaaaaa gttctgatcg aacatgaagt tcaaaatggc aaagatatca
     7741 aattgacaat cgatgcgaag gcacaaaaaa tagcttttga cagtctagga ggaaaagctg
     7801 gatcaactgt tgcgacaacg ccaaaaaccg gtgatcttct tgcgcttgct agctctccaa
     7861 gctatgatcc aaacaaaatg acaaacggga tctcacaaga agattacaaa gcttatgaag
     7921 aaaatcctga acatccattc atcagccgat ttgcgacagg ttatgctcct ggatctacgt
     7981 ttaaaataat tacagcagca atcggtctcg acaacggcac tatcgatcca aatgaagtgt
     8041 tgacgatcaa cgggcttaaa tggcaaaaag acagttcttg gggatctttt aaaacaacgc
     8101 gtgtcagtag tgatgtatca caagtagact taaaaactgc tttgatctat tccgataata
     8161 tatatgcggc acaagaaacg ttgaaaatgg gtgagaaaaa atttcgtaca ggcttagata
     8221 aattcatttt tggtgaagac cttgatttgc caattagtat gaatccagca caaatttcta
     8281 atgaagatag ctttaactca gatatcttgc tagctgatac tggatatgga cagggcgaac
     8341 ttctaattac tcctatccag caagcagcaa tgtattctgt ttttaccaac aatggcacac
     8401 ttgtctatcc taaattgatt gcagataaag agacaaaaga taagaagaat gtcatcagcg
     8461 aaacagcagt acaaacgatc gtgccagatc tgagagaagt tgtgcaagat gtaaatggta
     8521 cagcacattc tctttctgct ttagggattc cgttggcagc gaaaactggt acagcggaaa
     8581 tcaaagaaaa acaggatgta aaggggcaag agaacagttt cttgtttgct ttcaatcttg
     8641 ataaccaagg ttatatgatg gtcagcatgt tggaaaataa agatgatgat gattcagcaa
     8701 acaaacgagc atcggaacta ttgcaatacc tcaaccaaaa ttatcaataa aaaattgctt
     8761 tttaagtaca gtaaaaggac tgtggcgtta tcgtcacagt ccttttttca aataaacggt
     8821 tttcacgatg tctctttcac aacttctttt tgatttactc acacttcata aacttttttt
     8881 gtaaaatatt tgagaacaag tggagaaata agtgtactta ataaaatcac gataactaaa
     8941 ggtgaatagt actgtggttc gatcaattga ctttgctgtc caatttgtaa aatgatcaaa
     9001 gccatttctc cacgcgaaat cataccagca ccgaccatca atgaactatg ttgagaaaaa
     9061 ccggcaatct gagcaccaaa ataacctcca agcaatttgg tcaaaatcgc tacaagcgtc
     9121 aatatagaaa taaagagtag ttgttcacta aagtcagaaa aatcaacttc taatcctaca
     9181 ctgacaaaaa atactggtat aaatactgca tatcctaaag cctctacatt gtggtatact
     9241 tcttctttaa cctttgtctg actgacagct atcccagcaa aaaaagcacc aatgacagag
     9301 ctaagcccaa caagatccgc tacgtaagac attcctaaac aaataactag cgatacgatg
     9361 ataatagaag aatttgcgta cactttttct gcaaatgaaa gtaggaaagg cgcaatccat
     9421 ttgactaata agaaaataaa aacaaaataa attagctgtt caatcaaaac aagcggtaaa
     9481 gaagcattgc tagaagcttc ccccgttaga aaagataggc tgaaacttag aactaaaacg
     9541 actaaaatgt catctaccac agaagcaccc aaaattgttg atccttcttt tgtattcact
     9601 acgtttagtt cttttaatac ttctactgaa atactgacag aagttgccgc aagaataatc
     9661 ccaaagaaaa tcgcttcatt tcccgaaact tggaatgctt tgcctgtcaa ccagccaaaa
     9721 acaaccggga agatgatccc aagcaaagca acgaacatac caggtcggaa atattttttc
     9781 aaaagagata aatcactttc cagaccagct aaaaacatta ataagaacac accaatctcc
     9841 gaaaagtcat ggactagaat atcaggtttg acccaattca atccagcttg gcctagcaaa
     9901 acaccaacaa gtaattgtcc aatcactgct gggataccta atctccgcga gatatgtgag
     9961 ccaatcgttg ttgaaatcaa tatcaggcat aaaataccaa taaattccat tctcatcatt
    10021 cctttgtata aaatatagcc cgaacttagc ataacataca ttattgaaaa aataggaaaa
    10081 tatactcaca aaaaaaccaa caatccaaaa gatttttttg gattgttggt ttttatacgg
    10141 tctattttaa taactaaaaa tgattaacgt atagtcattt ttcttattct gatgaaattg
    10201 ataatctcct ggatgcccat gaaaatcaaa ataaagccga atatttggaa tagaagcatc
    10261 aaacttttga atggattgaa caataagacg aatccgccaa tcaacaacag aatactacta
    10321 taaacactcc aacttttagc ttttgtattc atgctgaaga acaactggaa caagctgttg
    10381 atgataacag ctaatccaag aagaatcggc aggatagaaa cgattgcagg tgcaaaagca
    10441 tagacgatca gagctaagat caggaaaaaa agaccactga acagaccgat actccaagaa
    10501 cctgttttcc ttttaaaacg gtaagcctca aaaagattca acaacccaag caaaacaaga
    10561 taggcggtga tcagataacc gataaaatga aaaacagcag aagggtttag cacaatcgca
    10621 atcccagaaa taatataaac agcagctctt aataaggcgt atttttgaat attttgttta
    10681 atcgtctcaa acatataaga aaacctcctt tgacttattt taacgtgaac tagtcatttt
    10741 accaaattaa atgttacaaa atgagcgaag gagaagaata tctctggaaa aatcaacttc
    10801 tgaggatctt ttccattttt ttgccttttg ctagctcatc gatcatttta tctaaataac
    10861 gaatttcttt catcaagtta tcctcgatgt cttctactcg tacaccacaa acaacacctg
    10921 taatcaagga acgtgaagga ttggggacag gggcttccgc aaaaaattgt tcgaaagtca
    10981 cttgtttttg tagttgatat tctagttctg tttgggaata acccgtcagc caacaaatga
    11041 tttcatctac ttcctctttt atacgatctt ttctctccgc ttttgctaca tacataggat
    11101 aaacgcttgc aaaacttgtc gtaaaaatac gattttgcgc cataatcagt cacctttctt
    11161 tttttcaaat tatttactac ttatagtata taagaaaaag agaagaaaaa gcgattattc
    11221 aaaaaaacaa aaaggattgt gacaaaa
//
LOCUS       DAZAOD010000088        11229 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000088 DAZAOD010000000
VERSION     DAZAOD010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.090"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            191..1450
                     /gene="lysA"
                     /locus_tag="ACHDPO_002275"
     CDS             191..1450
                     /gene="lysA"
                     /locus_tag="ACHDPO_002275"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFN3369883.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1437..2237
                     /gene="dapF"
                     /locus_tag="ACHDPO_002276"
     CDS             1437..2237
                     /gene="dapF"
                     /locus_tag="ACHDPO_002276"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFN3369884.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2240..3121
                     /gene="dapA"
                     /locus_tag="ACHDPO_002277"
     CDS             2240..3121
                     /gene="dapA"
                     /locus_tag="ACHDPO_002277"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFN3369885.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3118..3834
                     /gene="dapB"
                     /locus_tag="ACHDPO_002278"
     CDS             3118..3834
                     /gene="dapB"
                     /locus_tag="ACHDPO_002278"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFN3369886.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3840..4535
                     /gene="dapD"
                     /locus_tag="ACHDPO_002279"
     CDS             3840..4535
                     /gene="dapD"
                     /locus_tag="ACHDPO_002279"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFN3369887.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4551..5552
                     /locus_tag="ACHDPO_002280"
     CDS             4551..5552
                     /locus_tag="ACHDPO_002280"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFN3369888.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5549..6910
                     /locus_tag="ACHDPO_002281"
     CDS             5549..6910
                     /locus_tag="ACHDPO_002281"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFN3369889.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6870..8021
                     /locus_tag="ACHDPO_002282"
     CDS             6870..8021
                     /locus_tag="ACHDPO_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFN3369890.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7996..9165
                     /locus_tag="ACHDPO_002283"
     CDS             7996..9165
                     /locus_tag="ACHDPO_002283"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFN3369891.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9340..10719
                     /locus_tag="ACHDPO_002284"
     CDS             9340..10719
                     /locus_tag="ACHDPO_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFN3369892.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            11000..11229
                     /locus_tag="ACHDPO_002285"
                     /pseudo
     CDS             11000..11229
                     /locus_tag="ACHDPO_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3739 a         1955 c         2504 g         3031 t
ORIGIN      
        1 gtataaatag cttctaatag ttcgggtatt ttgtttttat aaccattttt attcttattt
       61 ttaaaaaaat atttcgaaat atactagaca attcagaaaa ttttgtttaa tattattcca
      121 ataaaattca aatctttatc aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag
      181 gaatgaaaaa atgacagaat tgataattgg cggagtcaca gcaagcacat tggcagaaaa
      241 gtataagaca cctctgtatg tgtatgatga agaaaagatg agacaaacga tgctgtcatt
      301 caagcgaggc tttgtatcga aacgttttga tacaaaagtg ctttacgcct ctaaagcatt
      361 ccaaacgatt gagatgctgc atttagttcg tgaatatgga ttcgggctag atgttgtcag
      421 tggtggggaa atctataccg ctttgcaagc tgattttcct agagatacta tctacttcca
      481 tggtaacaac aagacgccag aggaactgat ctatgcactt gaaaatgatt tgttgcatat
      541 tgttgccgat aatttgatgg aagttgaatt attagcagaa ttaagccaac gctatttaaa
      601 aaaaatctgt atcatgcttc ggttgaatgt cggagtagaa gcacatactc atgaatatat
      661 cgtcactgcg catattgatt caaaattcgg catgagctat gaaagtaaag agtgccaaca
      721 agcccttcag ttgataaaag aaagcagcta tctagagtta gaaggatttc atgctcatat
      781 cgggtcacaa atttttgatg ttactgcttg gttagctgaa atcgacaaat tgacgaatta
      841 cttaaccgat tttgaccaac ctctttcctt gaatcttggc ggagggtttg ggattcgtta
      901 tacacaaaat gatcagccga tcccagtcga agaggcacta aaaaaactga ttgaatatac
      961 ggaagaagct ttggaaaaac gaaaactgac cattcgtcaa ttactgatcg aaccgggtag
     1021 aagtattgtt ggagaagctg gtacaacact atacacgatt ggtttcatca aaaagacacc
     1081 acataaaaaa tattactttg tagatggcgg gatgacagat aatatccgtc cagctctgta
     1141 tcaggcagaa tacgattgtg atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt
     1201 gacgattgca ggaaaaatgt gtgaatcagg cgatgtggta attaaagaag cttatttgcc
     1261 gaaagcagaa tcgggtgatc ttttagctgt ttattccacg ggagcttatg gatactcgat
     1321 gagcagcaac tacaatcgag cgacacgacc agcagttgtt tttgtcaata atggccaatc
     1381 aagactgatt gttcgcagac aagcattttc tgatctacta aggggggaag tttcctatga
     1441 tccttcataa atataatggc tgcggaaatg attttatctt attagattac gcagaagaca
     1501 cagattatag tcaattagcc gcttctttat gcacaaaaga aaaatatgat atagacggat
     1561 tgatcgccgt aaaaatcgat ccgttggaaa tgatctatta caacaaagat ggcagccgcg
     1621 cgccgatgtg cggaaatggc attcgctgtt ttgctcgata cgtaaatgat cagaacatga
     1681 tgaatgaaca ggaattcaac gtagagacat tagcaggcac aagaaaaatt acggtgttgg
     1741 atccctcacc tttttattgc agcgtagata tgggagtgcc agatgattct ccggaaaaaa
     1801 tcaaagctaa tcaaacttat ccaataaaaa accaggaaat agagatcaat ggtgaaaaag
     1861 taacgatcac tagtttattt ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc
     1921 gtgaggaagt ctggagaaaa agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa
     1981 aaaccaatgt caactttgta gaagtagtca atgaacaaga attgatcgtc cgtacctatg
     2041 aaagaggagt aggttggaca cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg
     2101 ctaaggaaac tgggaaaatt tcagcagatc aggtagttgt tcacttggaa caaggagact
     2161 tgatgatctc tggtgaggat gcgatacaaa tggctggccc agcagttcat gaatggacaa
     2221 gaatattgga ggaatgaaga tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa
     2281 tgaagaggga tcagtagatt atgctggttt ggaaaaattg atccaattcc atttagatga
     2341 acaaacagat ggattattag ttttaggtac aacaggagaa tcttctacgc tcacacaatc
     2401 tgaggaggag cagatccttc aactgacagt aaagaaagtg gctggccgtg tgccggtgat
     2461 tgcaggagct ggaacgaata atacgaaaga aacgattgaa aaagcgaagc attttgcttc
     2521 tttgggggca gacgcacttt tggtcatcac cccttactac aacaaaacaa gtgatgcagg
     2581 actagctgct cattttacag caattgcaga agcctcaccg attccgctta ttttgtataa
     2641 tgttccttct agaacaggca tgtcgattcc aatccatgta ttagtaaatt tagcagaaca
     2701 tcctaatatc attggtttga aagaagcctc aggagatatg gcttatgtga tggatgccgc
     2761 tcggttgatt ggagaagaat tcttccttta cagtggaaat gatgatttga tcctaccagt
     2821 aatgagtgta ggaggaagcg gtgtaataag tgtatgggcg aatatccaac ctaaaatagt
     2881 ccatgaatta gtaaaagata cgcaggacgg aagatggcag caagcaaaag aaaagcaatt
     2941 aaatgcactt gaactgatcc atgccttgtt cagtgagacc aatcctattc ctgtcaaagc
     3001 agccatgtca ttattagact taccttccgg acctctacgc ctgcctttag tttctctttc
     3061 aaaagagaaa aagaaacaat tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg
     3121 aaaatcggac tgattggcag tggacagatg ggaaatagag tcgaagaagt tgcacaagaa
     3181 agaggagata cggtccttct tttacggacg gcacctaaag aagcaactac gcttgctttt
     3241 acggaactgc cagaactgct tattgatttt tctcatccag ataatttaga gaaaatcctt
     3301 tcgtatagct tatcatatca acttccgtta gtcattggca cgacaggtta tacacaatca
     3361 cagttccaag aaataaaaga acatgccaaa catgtacctg tgatgtatag tgctaatttt
     3421 tcgttcggca tcatggtgat gaatcaacta atcaagcaag cagctgcaat gttgcaaggc
     3481 tggcagatcg aactgattga aaaacatcat agtcgtaaaa aagatgcacc atctggtact
     3541 gcaaatatgc tgcttcaaac aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg
     3601 caagggaaaa aaagagaaga aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta
     3661 cctggtgaac atgatgtatt gtttgctgct actgatgaaa tatttacgat caaacatgaa
     3721 tctttttcta atcgaatctt tgctgcaggc gcagtagaag cagcggactg gttgaaagat
     3781 cagtcaccag gttattacaa attagaagat ttattaatgg acaaaggggt gtaaaaaacg
     3841 tggaagctca agaaatcatc cgctacattc aaacggcatc taaaaagacg cctgtgaaag
     3901 tctatctgaa tgtaaccgag ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa
     3961 gcagcttcgt tgtttttggt gactatgaga cgattgctcc ggttttagaa gctgaatcag
     4021 aaaaaatcat tgaaatcgaa atcgaaactg ctgcaagata cagcgcagtt cctttgctag
     4081 atattaaaaa aattaatgct cgtatcgaac caggtgctat tatcagagat caagtgtcaa
     4141 tcggcaacaa tgccgtgatc atgatgggag cgattatcaa tattggtgca gtaatcggtg
     4201 aaaacacgat gattgatatg ggtgctgtct taggtggacg agcgacagtg ggcaaaaact
     4261 gccatattgg tgcaggagct gtcttagcag gtgtgatcga accagcatcg gccaaaccgg
     4321 ttatcgtaga agacggcgta ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata
     4381 tcggaaaaga tgcagtcgtg gcagcaggag cagtggtttt agaagatgtg gcagcagaaa
     4441 ctgttgtcgg tggaatacct gcacgtgtat taaaaataag tgatgatcag acaaaagaaa
     4501 atacagcatt gattgctgcg ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa
     4561 tagatacctg tattgtgggg gcaaccggat tagtcggcca aacgatgctc aaagtgttag
     4621 aagaatatga ttttccagta ggacgattga aattattagc ttcaaaacgt tcagccggta
     4681 aagtttgtgt attcaagaaa aagaaacaca ctgtacagga attgacagaa acttcatttg
     4741 aaggatatga tttagcgcta ttttctgcag gtgcttctgt atccaaagag tttgcgccaa
     4801 tcgcacgaag tcagggacta tttgtcatag ataattcctc agcatggcgg gaagattcgg
     4861 atattccatt aatcgttcca gaggtcaatc tggaagacta tacattgaat cggctgattg
     4921 caaatccaaa ttgttcaacc attcaagcgg tacttccgct taaagcttta caagaagcct
     4981 ttggtatcca gcgagtcaat tattcgacct atcaagcagt ttctggttcc gggcaaaaag
     5041 gcattgaaga tcttcatcgt acgcaaaatg acgaggaacc agttttgtat ccttataata
     5101 ttagccaaac ggtgattccg gaaatcgatc agcctttgga aaatgggtat acaaaagaag
     5161 aacagaaaat gataaatgag acccgtaaga ttctgcatca gcctgctttg ccagtatcag
     5221 caacctgcgt acgtgtgcca atcgaaaatg gacatggagt ctctgtggca gttcaactgc
     5281 aaaaagagtt tacgacggaa gaaattagag agtgtctcag ccagtttcca gggattcaat
     5341 tagaagatga tctagcagca cataaatatc cgacgagcat tcttgctaga ggaacagata
     5401 tggtttatgt tgggaggatc agaaaagaca cttctttaga gaacggattg ttgttctata
     5461 cgactgccga taacatacgc aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt
     5521 taatgcagaa aatagcggag gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg
     5581 cggaacatcg atgtctcatg aagagcaatt caaaaaagtc cgtacaattg ttctttcaga
     5641 tcccaatcgc caagtgatcg ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa
     5701 agtaacagac ttactttatt tgatttatgc ttaccttcag catcatgttg attggacacc
     5761 cctttggaaa aggatttgtg atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt
     5821 acctattgaa gatgaactag cacgcataca gaaacaactg gaagacgaaa agataactga
     5881 agattattta gtaagtagag gtgaatatct gactgctcaa ctgatggctg agtatcttgg
     5941 ttaccagttt attgacgcaa aagacctgat tttctttgac tatgatggga aaatcgatca
     6001 ggaaaaaaca gcacaggaaa tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc
     6061 agggttttac ggggcgaacc ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga
     6121 cattaccggc gcgatactgg cgaagatgtt gcaagcggaa agttatgaga attggacgga
     6181 tgtttcagga atcatgatgg ctgatccgcg aatcatcgat catcctaaaa tcatcgagga
     6241 aatctctttt agagaactga gagagatggc ttatatgggg gctaacgttc ttcatgaagc
     6301 agctgttttc ccagttcaag aggctgatat ccccatccaa ataaaaaata ccaatgatcc
     6361 tttcgctcaa gggacaaaaa tatcgaatca cgaaatagaa aaggaaaatg gactgacagg
     6421 aatagctgga cgcaaggatt ttctttccat cactttattc aaacgtcata tgtccgatga
     6481 aatcgggttt atctggaaag caatgagcat ttttgctaaa catgagatat caatcgaaca
     6541 tattccttca gggatcgaca atatcggagt gatcgtctca gcagaagcga ttgccgataa
     6601 gttatttctc atcacgaaag aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat
     6661 cgaagactta gctttgatct ctgtcgttgg gggtccgcat aaagaattga ttggattatc
     6721 tgggaaagtg ttatcgatat tgaacaaatt agaaattcgc acatcgatct tatcacaagg
     6781 agcacaggag ttgaatctga tcatcggtgt accgaataat caatatgaaa cagtagtgaa
     6841 gggtatctat gaagggatgg tgaatacgga tgctgaaaga atatcgaatg gcactccatc
     6901 aaattcctga aatcgggttt catgaattca agacaaaaaa atatttatat gaacaagtaa
     6961 aaaacagcga ggccgttatc catgaaatcg gcgaaacagg actactcctt tattttgata
     7021 atcagcaaga agaaacgatt gcttttcgaa cagatatcga tgcactgcca gtcaaagaag
     7081 aaacgaatct ctcttttgct tctaagcatg aaggttatat gcatgcatgt ggtcatgacg
     7141 gacatatggc gatgctttta gggttgactg actttataac taaacacatt gaggatctta
     7201 tttataatgt agtactgatc tatcagccat cagaagaaat ttccggtggc gcacaaagcg
     7261 ttattcagtc aggattgttg gataaatatg aagtacaagc aatatttggc tttcatctat
     7321 ggcctggact agctaaggga gaagttttct ctcgaccagg acctttgatg gcacaaagca
     7381 gtgaaacaga cattatcatt aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa
     7441 tcgatagtct ggaggcagct gtacgatttt tgaagaatgt ttatgatttt gaccggcaat
     7501 taccggcaga gtggaatcat ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa
     7561 atgttttagc tggagaagtt attgtatccg gaagtatccg ttcttacagt tcagatatgc
     7621 aaaattattt gaagagggga ttagaccatt tagcagaaca gtttcactct acagctacta
     7681 tttcttttcg ctataatgac ggctatccag ctgtaatcaa ccatagaggc ttatatgcag
     7741 cactgttaga ttcaaacaaa ctacatgaat tagatgctcc agttcttcaa gccgaagatt
     7801 ttggcatata tacgcaacaa tatccatgtg tatttttctt tttaggtgtc ggtgataccc
     7861 ctgctttaca tgatccgacg ttcgattttg atatggatgt tttagaaaat ggtgtagaat
     7921 ggtacaaaac gattcttttt acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag
     7981 aggagcgagt aaataatgat gaatttatcc aatcgattta gtcctaggct ttctagaata
     8041 gaagtatcaa aaatacgaca attcgatcag caaatatcgt cgataccaga tgtgatcaaa
     8101 ctcaccctgg gagaaccgga ttttccaact cctgaacatg tcaagcaagc aggaatagca
     8161 gcgattgaag aagacttttc tcactatacc ggaatgagag gattagagga actgcgggaa
     8221 gcggcttgta tatttcagca acagcgttat ggattaactt atgatccgca aacggaagtt
     8281 ttgacgacag ttggtgcaac ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa
     8341 ggagacaagg ttcttattcc agcgcctgct tattcaggat atcagccatt agtggaacta
     8401 gctggtgctg aattgatccc gatagatact tctgacacag ggtttgtctg tcagccggaa
     8461 caatttgaac gagcatttga acaatatgga tcagctgtca aagcagtcat tttaaactat
     8521 cctaacaatc ctactgggac gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt
     8581 ttaaaaaaat atccggtatt tgttataagt gatgaagtat atgctgaatt gacttatagt
     8641 ggaacgcata tgtccatagc tacttatctt ccagaacaaa caatcgtgat aagcgggtta
     8701 tccaagtcac atgcgatgac tggttggcga gtgggcttta tttttgctca aaaagccctt
     8761 attgacgaac taattaaagt ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa
     8821 aaagctgcgg ctgaagcgct aataaatggg gtgaaagata gcgagaatat gaaagagcaa
     8881 tatcaaacac gaagagacta tctggtccag caattggcgc ctttaggatt tgaagtgacc
     8941 cagccaaacg gtgcatttta cttgttttgc aaactcccag ctgccattca aactgactct
     9001 tggcagtttt gtgtagaatt agcggaacag gcaaaagttg cgtgtatccc aggaattgca
     9061 tttggcccag aaggagaagg ttatatccgg atttcttatg ctagcagcat ggaaaaatta
     9121 catgaggcct gcaaacggat caaagacttt ttaacagaac agtgattcat agattttatc
     9181 aaaaaaacaa tcgttaattt tgcggtatat tctgcaagga gacgattgtt ttttaaattt
     9241 agttcaaatg aacgcgtttc ttttgattca taactaatgt aatgttaagt ttaaattgtt
     9301 tagaatgatt ttaaaagaat attcaaggag gtttcatcaa tggaaaaaat caaagttgtc
     9361 attgtaggtg catctcatgg agggcatcaa tcgatcttgg aactattgac acgatacggt
     9421 gaaaatgtag atatcacgct atttgaagca ggagactata tttccttcat gtcatgtggt
     9481 atggagctgt atttagaaga caaggtaaca gatgtaaatg atgtacgtaa tttcagacca
     9541 gaaaactttc cgcaatccaa tgttcatatt ttaaataatc acgaagtaaa aacgatcgat
     9601 gccgataaaa aaacagtaac ggttactagc gcatcagata acgaaacaaa agaatatcct
     9661 tatgacaaat tgattttgag ttctggtgtc aaaccaaaca atctgccagt accaggagca
     9721 gatctagaaa atgtctactt gatgcgtgga tacaattggg caaccaaaat caaagaaaaa
     9781 ttaaatgatc cggctattaa aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa
     9841 gcagcagaag caagccgaaa agctgggaaa gaagtcgtat tgcttgatgt gatcgataga
     9901 cctttaggca cttatttaga tgctgagatg acagatattt tagaacaaca cctaaatgaa
     9961 aacggtattg aagttttgac aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt
    10021 gaggcaatca aaacaagtga aaaagaaatc ccagcagatc tagtcattca agctgccggt
    10081 gtgaaggcaa atacagaatg gttaaaaggg atcgtcgact tagatgaacg tggctggatc
    10141 caaacaaatg aatacttgca aacgaatctt ccagatgtgt atgcagtagg agatgctaca
    10201 cttgcttatt ctatcccagc acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt
    10261 agagaagcac gttatgtagt aaaacatctt tttgaagaag taccaaacaa accgttcggc
    10321 ggagtcgtag gttcctctgc attaagtgtc tttgactatc attttgcagc aagcggattg
    10381 aatagcttta cagcagcaaa agcaggagta gatgtacgag tgtcttatta tgaagatacg
    10441 ttacgaccaa aatatgtacc agaagaacaa ggaaatccaa aagtgtccat ccaattattc
    10501 tcggatccaa tgacccatca attgctagga ggagcagtat tatctaccta tgatgttaca
    10561 ggtcaaggaa atgtattggc actagcgatc caaaacaaac tgactttaga agaactagca
    10621 gaagctgact tcttcttcca gccaggcttt gaccgacaat ggagcatgtt gaatctagcc
    10681 gctcaacaag cgttaggaga agaaccattt gtagaataag aaaacgaaat atttgaaaag
    10741 aggttgtgaa aaagctgcct tgcatcaagt aataagaaca gccaagtaaa aacagcttct
    10801 tatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10861 ttcaaaaaag ggactgtgac acgatttgtg taccgacccc caaaagttag accaaaaaat
    10921 ctaacttttg gaggtcggta ttttttatgg ttaaatatac ttttgaactt aaattaaaga
    10981 tcgttcatga ttatttggat ggcaaaggcg attggaccgt aaaaatccag atcaagagat
    11041 tgaagcggaa atgcttaaaa ttcgggagaa gcacaaggat tatggctgtt tacggatgac
    11101 caatgaacta agaaaccgcg gtttctctat caataaaaag aaagttcagc gcttgatcaa
    11161 gaagctagga ataaaagtaa cggcatacac gcgtaaatca cgtcgctaca attcttatcg
    11221 aggaaaagt
//
LOCUS       DAZAOD010000089        11100 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000089 DAZAOD010000000
VERSION     DAZAOD010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.091"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..217)
                     /locus_tag="ACHDPO_002286"
     CDS             complement(<1..217)
                     /locus_tag="ACHDPO_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369893.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMK"
     gene            511..1326
                     /gene="thiD"
                     /locus_tag="ACHDPO_002287"
     CDS             511..1326
                     /gene="thiD"
                     /locus_tag="ACHDPO_002287"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFN3369894.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1655..3106)
                     /gene="cls"
                     /locus_tag="ACHDPO_002288"
     CDS             complement(1655..3106)
                     /gene="cls"
                     /locus_tag="ACHDPO_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFN3369895.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3447..6113
                     /locus_tag="ACHDPO_002289"
     CDS             3447..6113
                     /locus_tag="ACHDPO_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFN3369896.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6477..7229
                     /locus_tag="ACHDPO_002290"
     CDS             6477..7229
                     /locus_tag="ACHDPO_002290"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFN3369897.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7251..8405)
                     /locus_tag="ACHDPO_002291"
     CDS             complement(7251..8405)
                     /locus_tag="ACHDPO_002291"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFN3369898.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8590..11031
                     /locus_tag="ACHDPO_002292"
     CDS             8590..11031
                     /locus_tag="ACHDPO_002292"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFN3369899.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         3604 a         1962 c         2357 g         3177 t
ORIGIN      
        1 ttttcatctg tttatgaaat tctttttttt cagtaaacat aaaggtttgg gtatcgtaac
       61 cttcttcatg taggaaatag attattcctt tttctgtgtt ttgcgtataa gcttttatac
      121 tcctgtcttt tttgaaagaa cagatcgtat agccatctat ttggtctggt agtcgtttga
      181 ttttcttcaa aatgactttt ttatcctcaa gtttcatttt tttcacctga ctttattttt
      241 ttcatatgga aatcatagcg cctttggtta tatgaaaaca agaaggatac tgaaatatat
      301 ataaatcaaa tagtggttat ttattattag aatagcgaat acaaataaac gaccactatt
      361 ttctgattta ttgcaaatgt tttttcaaat aaatttgatt accaagaaaa ggtagtggta
      421 tatttactga gggatacttt gaaaaacata tgatagaaac agtaacagta ttatgaaaaa
      481 tctttttata aaaatggagg aatcgatttg atggaagatc agtatgtaca agcaatgacg
      541 atcgcaggat cagatagcga tggaagcgca gggatgcaag cagatatgca tacattcttt
      601 acaagaaatg tttacggtgt ttctgtcatg accgcatgtg ttgcaggtaa ttcttacgga
      661 atcggagcaa gtgtgacatt gccaacagat tttatcgaca aagaatttga actgattgcg
      721 aaggactttc aaatacgtgc agctaaaaca ggtatgctag cagattcaaa gttgattgag
      781 acagttgtaa aaaattacca aaaatatgat tttggaccat tagtcgtgga tcccgtaatc
      841 gtaacgaaac atggaaatct tttactagaa gaatctgctt tgcaaagctt gaaagaaaag
      901 cttgtccctt tggccgaagt actgacacct aatttttatg aagcagaaaa gctgactgga
      961 cggacattag cagctgaaga agattttgtg caagcagcaa aagaactgca agatatgggt
     1021 gcaaaaaacg ttatgatcaa aggacatcat gctaaaaatg cgcagcaaga aacagtcaat
     1081 gactacgtat tgttcgaatc aggaaaatca ttttggttaa atgcaccatt ttatcctacc
     1141 gaccggatca acggaactgg cgattcgcta tctgcatgta ttgcagctga gttagcgaaa
     1201 ggaaaaacag ttgaacaagc gatccgattg gcaaaagact atgtaaaccg tgcaattcgt
     1261 gaagaaataa atgtagggca caaatatggc cccatcaatc attgggcagc tggtgaatta
     1321 gagtaaaaga aagaagttgt gaaaaagttg ccctgcatca agtaataaga acagccaagt
     1381 aaaaacagct tcttatgttt ttaacttggt tggacttatt accgcagatg caagcttttg
     1441 aacaccgttt aagaaagagg tcgtgagcct gccgtccagc tccgagtcac aaggaacaag
     1501 ttcaaaaaac agcttctcat gtttgttgaa tattgtgact tgtgaccgag gagttggcag
     1561 gagaacaccg tttgttcgga agaagggact gtgacaagat ttttgtcaca gtccctttaa
     1621 tcttagtata tttttctcta cttgaataaa aaaattatag gattggagaa aataatcgag
     1681 aaatttgttg cttgaataat agccagttag acatttcctt gactgtttca gttgtcatgg
     1741 atgaacaatg tgtctcatct tctttgaact gagtagcaag ttcttctaaa aactcaggat
     1801 cgtaaatgac agcacttgtt tcaaaattca atcggtagct acgaatatct tgatttgctg
     1861 aacctaccat gcagatttca tcatccatta tcaatgtttt tgcatggagg aagccgttct
     1921 catagacaag gatttgtaca ttttccttga tcagctgccg agcataatat tgtgttgctc
     1981 gataaataaa aggatgatcc ggtttgttgg gaatcatgat tttcacatct acaccagagg
     2041 cagttgcgat ttttaaagca gcaatgacac tttcatcagg aacaaggtaa ggtgtctgta
     2101 tccaaacacg ttttttagca gaagtaatca atttgataaa tgaaagcttg atttgttccc
     2161 tttcgttatt cggtccgctt gaaacaagct ggatggatgt atcagcaagc ttagattcat
     2221 ctcgatctgc ttttttaaag aaataattca aatgatagcc gacctttttt tcttcaggta
     2281 ccgagacgtt ccagtctgtt aagaagcgaa gctggagcaa agaagaagcg gcaccgaaaa
     2341 tccgtatatg cgtatcgcgc caatagccga atttttttgt tgtatttaca tattgattgg
     2401 caatattgaa accaccggta taactaatct ttccatcgat cacaacgatt tttcggtgat
     2461 catggtaatt caatcggaaa cgaagtaatg ccctttgtga ggtaacaaat gtatggacat
     2521 gtccaccatt tttgattaga cgattgaaat cttttgcttt tgtgccatga gagccaaatg
     2581 catcatataa tattcgaact tccacgcctt ctgcggcttt ttcttctaaa acatgtaaga
     2641 cttgctggcc gatattatct gtcacaaatg cgtaatattc gatatggatc gaatgtttgg
     2701 ctttttttag atcttgaagc agtgaatcca atttctcttg tccgtctgtg agaagagtga
     2761 cagaattcat tcttgtcagc ggcatacgat ttaatgaaga gaagaagtca acaaattgct
     2821 gtttgtcttt atcgcccatg tcaggatcgt aatgttcaat ggtatctcct ctaaaagact
     2881 gaaagttttc taattctttc aagtcacttt gtcggagata gaattttttc ttatccgtta
     2941 atccacgtcc gaaaaataaa tataatacaa agcccacccc aggaagggca aacaatacta
     3001 agagccatgc ccaaatggct gctacatctc ggggtttgat caaaatagcc accaaagcaa
     3061 taagtgcatt taatagataa agggcggtta taatactaga taccacaaaa atgttcctcc
     3121 ttacatacaa taacattagt atagcatgat agaagaaaga agcctaccaa ggtgaatata
     3181 cttttcactc ctttcatgaa aatgtaggta aatcgggcta aagtagttgc tttttgtagg
     3241 ttaataaggt aggatattag tacagttgaa tatctcctta ggggagtaac cggcaacgtt
     3301 tgttgcgata atatcaacag taagttaacc aaatggtttt ctggtattgt atgaaatggt
     3361 gagacctaag acaaatgcgt atttgtctta ggtctctttt ttttcagaca ggactagggc
     3421 caagatcaaa aaatggggga tgaaatttgg aaaacaagga acaagcacaa caagcggtct
     3481 ataaagaaac gatcgactcg ttgatgcagc aaacgcagag ctcaaccgat ggattgagca
     3541 ccacgcaagc gaaggaaaaa ttagaaagag atggcttgaa ccagctaaaa gaaaagccga
     3601 agaagccaac ttggaaattg ttcttagaaa ctttcaaaga tgcaatggtt atcgtattgc
     3661 tgattgtcgc actgattcag atggtcatgg gtgactacat cgaattctta gttatttttg
     3721 cagtattgat gttgaattct ataatcagtg ttgtccaaac aaaaaaagca gaaggttctt
     3781 tagaagcgtt gaaaaacctt tcagcgcccg atgctcgagt gattcgtgat ggtaaggaaa
     3841 aaacgattcc ggcaaacgaa cttgtggtag gagatatcgt gttgttagac gcaggcgatt
     3901 atgtacctgc tgatggacgt ttactagatg cgggatcatt aaaagtagat gaaggtatgc
     3961 tgacaggaga gtcgacttct gcagaaaaag aagtaacgga tatcacaagt acggtaccaa
     4021 tcggagatcg tacaaatatg gtattcagtg gaacgatcgt aacttacgga cgcggtaaat
     4081 tcttagtgac ttcaactggg aataatacgg agatcggaca agttgctggc cttttggaat
     4141 caacaactga gcaagtcact ccgttacaac gaggtctgga taaattcagt aaaaaactaa
     4201 gtttggctat tttggcattg tctttattga ttttaggtat ccaactgttt cgtatttatc
     4261 ttggagaagg tacaggagat atgactgcag atatcgtcag cgcagtgatg tttgccgtag
     4321 ccgtagccgt agctgctatt ccagaagcat tacagtctat cgtaacaatc gtgttatctt
     4381 tgggaacgaa taaaatggca aaacgtcatg ccattattcg gaagcttcca gcagttgaaa
     4441 cacttggttc gacaagtatc atctgtacag ataagactgg tacattgaca caaaacaaaa
     4501 tgacagttgt tgactacttt ttaggtaatg gcgatactgg ggatttcaca aatgaccctt
     4561 caaaatggac agctgacgaa cgtcgcttga tcgaaatcag tgttttagcg aatgatgcat
     4621 cgatcagtga agacggtact aaattgggcg accctacgga agtagcgttt atcgacttta
     4681 gtgaaaaatt aaaccagcct tatcaggaaa tccgaaacaa ctacccaaga caagcagaac
     4741 ttccttttga ctcagatcga aaattaatgt ctactggaca cacaattgat aacaaaaatt
     4801 acttgtttgt taaaggcgga ccagatatcg tcttccaacg cagtaaaaaa gtattgctaa
     4861 atggtgaagt cgttccgatg acggatgaat tgatgaaaaa attccaagag caaaatgaag
     4921 ctttttcaac acgcgcatta cgtgtactag cttttgctta ccgtccactt gataattttg
     4981 atttatcatt tgaagatgaa gacgatttga tccttgttgg tttgcttgct atgatcgatc
     5041 ctccacgtgc tgaagtgact caggcggtaa cagaagcaag aagtgcagga atcaaaacaa
     5101 tcatgattac tggtgaccac aaaacaacag ctgttgctat cgcaaaacaa atcgggattt
     5161 ttgaagaagg aaacctggct ttgaccggga cggaactaga tgaattgaca gaagatcaac
     5221 taaacgaagt tttagaaaaa gtcactgttt atgcacgtgt ttcacctgag aataaaattc
     5281 gtatcgttcg tgcttggcaa aataaaggtc atatctcagc tatgacaggt gatggtgtaa
     5341 atgacgcacc agcattgaaa caagcagaca tcggaattgc tatgggaacg ggtacagatg
     5401 tggcaaaaga tgcagcagcg atggtattga cggatgataa ctttgcttct attgtcagcg
     5461 cagtagaagt aggacgtaat gtgtttgata atatcaagaa agctatttct tatctatttg
     5521 caggaaattt aggtgcgatc attgcgatca tctttgcctt agttgctgac tggtccaatc
     5581 catttacagc attacaactg ttgttcatca atttagtcaa tgattcactg ccagcaattg
     5641 cattaggtac agaaaaagct gaacctgcta cgatgaaccg cccgccaaga gatccaaatt
     5701 caggaatctt tacggacaaa acattgattt ctgtaacgta tcgtggtgtg ctgattggga
     5761 ttgctgttat ctttgctcaa tggcttggca tgcagcattc acctgaattc ggtgtagcca
     5821 tgtcattttc aacattgatt tggtgtcgga cattgcaaac attcccagca cgttcaaaca
     5881 cacaaacagc tatccaagca gggttcttct ctaacagaag tgtcttacta gctgtagttg
     5941 tatgtagcgc gctttactgc ttaacaatga tcccaggact gaaagaagtc ttctctatcc
     6001 catcagcatt tggattgaca gaagtcttta catgtatggg aatcgcactt gtgacaattg
     6061 ttttgatgga aatcactaaa ttgatcattg tacgagtaca aggaaataaa taaaacgaat
     6121 caacgaggtt gtgagcctgc cgtttaattc tgagtcacaa ggtgcaattt caacaaacag
     6181 cttctcatgt ttgttgaata ttgtgacttg tgaccgaaga gttggcagga gaacaccgtt
     6241 taaggaagaa gttgtaaaat cagcattttg agctaatact gagggtcatc tgattggaca
     6301 ctgtttattc ggaaagaggg actttgacac gactttggtc acagtccctt tttttattta
     6361 tgatagacgg aaagccaatc attttattat tcatcaaaag agatagaata gataaaagag
     6421 gagaatgatt tattccgaaa agtgaaaaca tataacaaaa aattagagga aatcaaatga
     6481 atgaaaaaga atgggatgaa tttgctgaag aatattatga aatccagcaa gaatcgcaag
     6541 taactattgc tgaagatgta aaaaattatc tgaaaacgga gaaagtcctg cctgctgaaa
     6601 cagcagcaga cgttgctgga ggatctggca gatttctttc cttagcaaaa gaaattaatc
     6661 gctatgattt gatcgatttt tcttcaggaa tgctagaaaa tgcaaaaaaa gaagcagaaa
     6721 aaaatgagtt gccaaatgtt tcctttatca aacagtcgtt agaagaattt atccaatcaa
     6781 atgagacata tgaaatggtt tttacagcag caaatccagc attggtacat cttattcaat
     6841 tagaaaaatt gatgaaaaag tcaagcaaat ggtgcgtgat aatcagagta gtggaatcaa
     6901 tcgatgatgt tttttatcct atcgaaaagc aactaggaat gatagaagaa gatcctaata
     6961 catcgccagt tgtaatggat caatttgaaa catacttaat tgatgaagga ttcaaagtga
     7021 agaaaaaaga ttttacttat tttacacagg aatcaattac tgaagaattg atgaagctat
     7081 actatgacgc gtacgcaaaa gatcctgttg tgaccaggta cattcgcaaa ctattcagtg
     7141 aaaaacgaga aatccttagt acgactaagc tgacctatag actgctcctt tggtccgcag
     7201 ataaaaaaag aacctttcac gactcgtgaa gggttctttt tatgatttta ttatattttg
     7261 tagtaacgaa tatcattttc gatctttgta atcgaaaaag gtacatctga agtatattct
     7321 gcacattctc cgtgttcagg aagcgtctca ctgaaaatcg tttcatattc gtcaacagtg
     7381 atccgtgttc gagaatctag catctcttga tgagattgtg cgaagagata ttcttgatag
     7441 ttttcttcca gataacctgt aaaaaattca cttactgcac cagaaccgta gctgaataga
     7501 ccgatgcgat ctcctggctg tagtgatttc gaattttcca gtagagaagt tagccccagg
     7561 tataatgaac cagtgtaaag attaccgatt cgtcggctgt aacggatgct ttcttcatag
     7621 cgagccataa gacgttcctg attttcttcg tctgtttggt ctaatacgct ttgcaatgcc
     7681 ttttttccca tcttagtata cggaatatgg aaagcaatcg cctgataatc ttcgagtcct
     7741 cgacccgaca attctttatg tcgattccaa actttttgga atgattcgat atacgtagaa
     7801 ttagataaag gaccatcaac aacaggaaat tcgctataat ctggacgcca gaaatcatag
     7861 atatcttctg tcagaaatac gctgtcgtct tcaatcgata aaatacgcgg gttttgagtg
     7921 atcatcatcg caacagcacc gacaccttgc gtcacttcac caccgcttgc caagctgtaa
     7981 cgagcaatat cacttgctat gactagtact tttcgttctg gatgattttt gacatattct
     8041 ttcgccatgt gcaaagctgc ggtgccaccg tagcaagcct cttttacttc aaaagaacga
     8101 gcaaaagatt ggattttcag taaatggtgg ataattaccg cactcgcttt tgaatgatca
     8161 atcccggatt ctgttccgac gatgaccatg tcgattagct cacggtcttt ttctgttacg
     8221 attttgctgg cagcatttgc tcctagtgta atgatgtctt catttgcacg attgactgcc
     8281 atttggtctt gaccaatccc tatatggtat tttgcaggat catccccacg gctttctgcc
     8341 aactctgtca tatctaaata taaattagga ataaaaaagg aaagacgatc aatccctatt
     8401 ttcatttcaa cacctcttta cttatgataa aaaacttact ttactaaggt atcataaaaa
     8461 gattaaaaga aatataaaaa agagaatatt taaggattgt taaaatttaa tcttagaaaa
     8521 aaataactgg aacaagagct atttgttttt acagcaaaga atggtatatt tttgtaggag
     8581 gtggcttact tgaaagaagt cgttatgata gatgctgcaa gaacgccgat aggaaagtat
     8641 cgcggaagtt taagtccatt tactgcagtt gaattaggca cacttgtgac taaaggatta
     8701 ttagataaaa caaaactgaa aaaagataaa atcgatcaag taatatttgg aaatgtcctg
     8761 caagctggta atggtcaaaa tgttgccaga cagattgctt tgaacagcgg tctccctgta
     8821 gatgtcccag caatgacgat caatgaagtt tgcggatctg gtatgaaagc agtgatctta
     8881 gcacgccagc tgatccaatt aggtgaagca gaacttgtga tagccggcgg aacagagagt
     8941 atgtctcaag cacctatgct gaaacagtat cagtcagaaa caaatgaata tggtgaacca
     9001 atttccagta tggtcaacga cggattgact gacgcatttt caaatgcaca tatgggatta
     9061 accgcagaga atgttgcaac acaattttct gtgagcagag aagagcagga tcgctatgcc
     9121 ttgtcgtccc agttgaaagc agcacatgct gtcgaagccg gtgtattttc tgaggagatc
     9181 atcccagtca agatttctga tgaagacgtg ttatctgagg atgaagcagt tcgtggaaat
     9241 agtacattgg aaaaactggg cacgttacgt acagtattct cagaagaagg aactgtaaca
     9301 gcaggaaatg cttccccgtt gaatgacggt gcctctgtgg tgatccttgc atccaaagaa
     9361 tacgcagaaa ataataatct gccttattta gcaaccatca aagaagtagc ggaggtcggt
     9421 attgacccaa gtatcatggg aatcgctcca atcaaagcca ttcaaaaatt gacagataga
     9481 tcaggaatga atttatcaac aatcgatctt tttgagatca atgaagcatt tgcagcttct
     9541 tctatcgtag ttagccaaga actgcagtta gatgaagaaa aggtcaatat atatggagga
     9601 gcaatcgcat taggccatcc aattggtgca agcggtgcac gtatcttgac tacattagct
     9661 tacggattgc ttcgtgaaca gaagagatac ggtattgctt cattatgtat tggtggaggt
     9721 ttaggcttgg cagtcttgtt agaagcgaat atggagcaaa cacataagga tgtgcaaaaa
     9781 aaaaagtttt atcagcttac gccatctgaa cggcgcagtc aattaataga aaaaaatgta
     9841 ttgacacaag aaactgcgtt gatttttcag gaacaaacac tttctgaaga gctctccgat
     9901 cacatgatcg aaaaccaagt gagtgaagtg gaaatcccaa tggggatcgc gcagaatttt
     9961 caaatcaatg gcaagaaaaa atggattccg atggcaacag aggaaccatc tgtcattgca
    10021 gctgcaagta atggtgcaaa aatctgtgga aatatctgcg cagaaacacc tcagcggctg
    10081 atgcgagggc aaatcgttct atcaggaaaa tcggagtatc aagcagtgat caatgcagtt
    10141 aatcatcgaa aagaagagct gattctttgt gcaaatgaaa gttatccttc aatcgtgaaa
    10201 cgcgggggcg gtgttcaaga tatctctact cgggaattca tggggagttt ccatgcatac
    10261 ttatctattg attttttagt ggatgtaaaa gatgcaatgg gcgctaacat gatcaactcg
    10321 attcttgaga gtgtggcaaa caagttacgg gagtggttcc ctgaagaaga gattctattc
    10381 agtattttaa gtaattttgc tacagaatca ttggcttctg cctgttgtga aatcccattc
    10441 gaacgcttag ggagaaacaa agaaatcggt gaacaaattg ccaaaaaaat ccaacaggca
    10501 ggggaatatg cgaagcttga cccttaccgt gcagcaacgc acaacaaagg gatcatgaat
    10561 ggtatagaag ctgtagtggc agctacagga aatgatacac gtgcggttag cgcttcgatc
    10621 cacgcctacg cggcaagaaa tggattatac caaggattaa cagactggca gatcaaaggg
    10681 gataaactag ttggaaaact aacggtgcct ttggctgttg ccacagtagg cggagcttcc
    10741 aatatcctgc caaaagcaaa agcatcttta gctatgttag atattgattc agccaaggaa
    10801 ctagcacaag taattgctgc agtagggtta gctcaaaacc tggctgcttt gcgtgcatta
    10861 gttacagaag gaatccaaaa aggccacatg ggacttcaag ctcgttcatt agcgatctca
    10921 attggggcta ttggtgagga aatcgagcaa gttgcgaaaa aattacgtga agcagaaaag
    10981 atgaaccagc agacagctat acaaatattg gaaaaaatcc gggaaaaata aaaaagcaat
    11041 atctttagaa gaataaagca agatttacag ttattttatt tactgcagat cttgcttttt
//
LOCUS       DAZAOD010000090        10604 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000090 DAZAOD010000000
VERSION     DAZAOD010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.092"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            8..81
                     /locus_tag="ACHDPO_002293"
     tRNA            8..81
                     /locus_tag="ACHDPO_002293"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="ACHDPO_002294"
     tRNA            101..173
                     /locus_tag="ACHDPO_002294"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="ACHDPO_002295"
     tRNA            201..274
                     /locus_tag="ACHDPO_002295"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="ACHDPO_002296"
     tRNA            288..361
                     /locus_tag="ACHDPO_002296"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="ACHDPO_002297"
     tRNA            385..474
                     /locus_tag="ACHDPO_002297"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="ACHDPO_002298"
     tRNA            487..560
                     /locus_tag="ACHDPO_002298"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="ACHDPO_002299"
     tRNA            579..654
                     /locus_tag="ACHDPO_002299"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="ACHDPO_002300"
     tRNA            656..726
                     /locus_tag="ACHDPO_002300"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="ACHDPO_002301"
     tRNA            740..813
                     /locus_tag="ACHDPO_002301"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="ACHDPO_002302"
     tRNA            838..925
                     /locus_tag="ACHDPO_002302"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="ACHDPO_002303"
     tRNA            947..1018
                     /locus_tag="ACHDPO_002303"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="ACHDPO_002304"
     tRNA            1041..1130
                     /locus_tag="ACHDPO_002304"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="ACHDPO_002305"
     tRNA            1143..1216
                     /locus_tag="ACHDPO_002305"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="ACHDPO_002306"
     tRNA            1235..1307
                     /locus_tag="ACHDPO_002306"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="ACHDPO_002307"
     tRNA            1311..1383
                     /locus_tag="ACHDPO_002307"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="ACHDPO_002308"
     tRNA            1388..1458
                     /locus_tag="ACHDPO_002308"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="ACHDPO_002309"
     tRNA            1471..1544
                     /locus_tag="ACHDPO_002309"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="ACHDPO_002310"
     tRNA            1556..1627
                     /locus_tag="ACHDPO_002310"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /gene="metK"
                     /locus_tag="ACHDPO_002311"
     CDS             1893..3086
                     /gene="metK"
                     /locus_tag="ACHDPO_002311"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFN3369900.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="ACHDPO_002312"
     CDS             3216..4688
                     /locus_tag="ACHDPO_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFN3369901.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="ACHDPO_002313"
     CDS             4771..5559
                     /locus_tag="ACHDPO_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFN3369902.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="ACHDPO_002314"
     CDS             complement(5626..6294)
                     /locus_tag="ACHDPO_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFN3369903.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="ACHDPO_002315"
     CDS             6409..8121
                     /locus_tag="ACHDPO_002315"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369904.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9896
                     /locus_tag="ACHDPO_002316"
     CDS             8124..9896
                     /locus_tag="ACHDPO_002316"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369905.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(9978..>10604)
                     /locus_tag="ACHDPO_002317"
     CDS             complement(9978..>10604)
                     /locus_tag="ACHDPO_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3369906.1"
                     /translation="KTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFL
                     TGLRYGELISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQ
                     LIEENKLIKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHIS
                     LLTELGIPLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT         3092 a         1864 c         2366 g         3282 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa agttaaatta
     9901 aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt ttttataagg
     9961 ggcagaaaag gggcaattta aatttctatt tttcctagtt tttctactag ttgattttgc
    10021 atatttttag ttgtatgagt ataaatcttt aatgttgttt ttgaatcttc atgtcctaca
    10081 cgatccataa tggcttttaa tgggattcct aattctgtaa gtagagaaat gtgggaatgc
    10141 cttaacatgt gagaagaaac ttttttatct aggtttaatt ctttggatac tgctcttaaa
    10201 gattgattat atgcttgaat agatatcggg ttaccatttt tagagatgaa aatgtattta
    10261 tctttattat tcttaattaa tttgttttct tcaattaatt gatctatgat ttctttagca
    10321 ttacttgata attcaatggt tctataagaa cctgtatttt tagttgttgt tttaattttt
    10381 aactcgtaat cataagtacc agaaaccgta attttattac catcataatc agattcagtc
    10441 aaagatatca attcaccata acgtagtcca gttaaaaaca aaaatttagt aattaaagaa
    10501 taacgtgact gttgatgtga acttttttgt ttactagcaa tcatttgaac ttcttctttt
    10561 gataaataac catctttttc tttttttatt tcttcgtttg tctt
//
LOCUS       DAZAOD010000091        10565 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000091 DAZAOD010000000
VERSION     DAZAOD010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.093"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..605
                     /locus_tag="ACHDPO_002318"
     CDS             <1..605
                     /locus_tag="ACHDPO_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369907.1"
                     /translation="VKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLLTVAMFLL
                     PEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKTYQDMLDV
                     FNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRITAGKGGI
                     TDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1055..2104
                     /gene="trpX"
                     /locus_tag="ACHDPO_002319"
     CDS             1055..2104
                     /gene="trpX"
                     /locus_tag="ACHDPO_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFN3369908.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2101..2982
                     /locus_tag="ACHDPO_002320"
     CDS             2101..2982
                     /locus_tag="ACHDPO_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369909.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            2985..3755
                     /locus_tag="ACHDPO_002321"
     CDS             2985..3755
                     /locus_tag="ACHDPO_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369910.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4034..4888
                     /gene="aroE"
                     /locus_tag="ACHDPO_002322"
     CDS             4034..4888
                     /gene="aroE"
                     /locus_tag="ACHDPO_002322"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFN3369911.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5066..6229
                     /locus_tag="ACHDPO_002323"
     CDS             5066..6229
                     /locus_tag="ACHDPO_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFN3369912.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6346..6756
                     /locus_tag="ACHDPO_002324"
     CDS             6346..6756
                     /locus_tag="ACHDPO_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFN3369913.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6930..9158
                     /gene="topB"
                     /locus_tag="ACHDPO_002325"
     CDS             6930..9158
                     /gene="topB"
                     /locus_tag="ACHDPO_002325"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFN3369914.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9329..9613
                     /locus_tag="ACHDPO_002326"
     CDS             9329..9613
                     /locus_tag="ACHDPO_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369915.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9773..10009
                     /locus_tag="ACHDPO_002327"
     CDS             9773..10009
                     /locus_tag="ACHDPO_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFN3369916.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10006..10404
                     /locus_tag="ACHDPO_002328"
     CDS             10006..10404
                     /locus_tag="ACHDPO_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFN3369917.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3687 a         1771 c         2228 g         2879 t
ORIGIN      
        1 tagttaaatc gagagtacaa gaaatgaatg aacatttctc agtgtcattc gcagaaaatc
       61 caagtaagta ttttcgacgt cttgtttttc tgctcatctt atcattgctg ttaacagttg
      121 caatgttttt attgccggaa aaaatccgag aagagcaagt aaatagtctc gtttattcgt
      181 ccataccaac cagcaaattg aaaccttttg attacagcaa agctgatcag aaaatcaaac
      241 aaagccgggc gatatcggtg atgttcagca aaccgaacgg gaaaacctat caggacatgc
      301 ttgatgtttt taatgatcct gagcttatgg aagaattgaa tcgaccgatc ttttattatc
      361 cgatcgttta tgatgtacat gaactggaac aaaaatataa catacgaacg gatgaagtga
      421 catttatttt ctttgatgga ggaaaagaag caaatcggat aactgcgggt aagggaggaa
      481 taactgattt tgataaggag ttgatccctg aactgaatcg acttccgtta gccaatatca
      541 aacaattaga agaagaattg gatagaacgg gagtaacttc ccaaaattcc gagattgcta
      601 attgagacat tggcgcgatg aaacggtggg tctatatagc gctattttta attatcagaa
      661 caagtgatgt ttgatcttca aaataacaaa taaaaaatta aaaaatatag ttgacgaaat
      721 tcaaaaattc gattagactt aaatcaattc ttaaggaaag ggtgacctgt aatgaactta
      781 tcaaaacgta tttcagcaga aaacaaaaaa aattggcgca gctggcgtag ataagttgta
      841 ttaatggtga gactttccca tagatacaac tttttagagt gcatttctaa agcttgtatc
      901 tatgctagac atgaacattg actgccgcat agattagaat ctatgcggtt ttttgtgtaa
      961 agacaatgac cgctttggcc attgtctttt tttgtagact ggatacttgc ctgattataa
     1021 taaataaaaa gattgacttt gcaggaggaa aaaaatgaaa aacaaacgat taataacagt
     1081 tgtagtaatt attttagttt atttagcagg tgcatttatt tatggaaaag cctcaggcga
     1141 aaaagaaagt acttcgacga accagacaaa aaaaacaaca gttgttgggg tattgcaata
     1201 cgtgagccat ccggcattag atgagattta tcgaggaatc aaagatggtc tgaaagaaga
     1261 aggattaaaa gaaggagaaa atcttgagat caaatttcaa aatggacaag ccgatcagag
     1321 caagctagcc acaatgagtc aacagctagt acaatctgat ccagatgcct tgattggaat
     1381 cgcaacacct gccgctcaat cattagcaaa cacgacttca tcgatcccag ttgtgttagg
     1441 tgctgtaacg gatcctgtgg gggctggatt agtcgcttct ttagagaaac ctggtggtaa
     1501 tgtaacaggt gtttctgatc agccgcctgt tacttcacaa atcaagcttg cttctgattt
     1561 gttgccaaat gcaaaaaaag tcggaatctt gtatgcttct tcagaggata attcaaaata
     1621 ccaagtagca caagcagaag aagctgcaaa aaaagaaggg ttagaatcag taaaatatgc
     1681 ggtgccttcc actaatgaga ttgcacaaac ggttcaagtg atgagccgac aagtcgattt
     1741 tatctatgtt ccattagata ataccattgc caatgcgatg caaacagtgg taaaagaagc
     1801 aaacaaagca aatatccccg tcattccatc tgtggataca atggtggaac aaggtggact
     1861 agcaacaatc gggatcaatc aatatcaatt agggcttcaa agcggtaaga tggcggcaga
     1921 acttgcgagt ggaaaagaaa aaccggaaac gacgcctgtt tatacatttg atcaagggga
     1981 tacagtgatc aatcaatctc aagctgatcg cttaggaatc attgttcccc aatcgatgaa
     2041 ggaaaaagcc aaaatcatta cagatgactc gcagcaagaa acatctaagg aggatgacaa
     2101 atgatcgtat cagctatttc acaaggcatg ctttgggcaa tattaggatt agggattttc
     2161 atgacttatc ggatcttaga ctttcctgat atgacgacag aagggtcctt cccattaggt
     2221 gctgctgtct gtgtgacagc tattactcat ggggtagcgc cgattgtagc tacattatta
     2281 ggcgtaggtg ctggcatgat agcaggactc gttacggggt tactttatac aaaaggaaag
     2341 ataccggtta ttttagcagg gattttagtg atgtcaggat tgaactcagt tattttgttt
     2401 gtgatgcgaa caccaaatct ttctttattg aatcatccga ttctacaaga cagcttccat
     2461 cgctttgggt tacctgatta ctttgacaca gtccttcttg gcttcatctc tttgggcatc
     2521 ttgattgctg tactgctatt cttcttcaat acagatttgg gtcaaggcta tattgcgaca
     2581 ggagacaacg aaacgatggc tcggtcgtta gggataaaaa ccgatcgtat gaaaatttta
     2641 ggtttaactt tgtcgaacgg tgtcattgca ttatccggtg cgctgattgc ccagaacgac
     2701 ggatatgcag atgtaaataa agggattggc gtaatcgtca tcggtcttgc ttccatcatc
     2761 atcggtgaag tgatcttcca agaattgacg ctagcagaaa gattgattgc tattgttgtc
     2821 ggcagtatca tttatcagct attgatttta gtagtaatca aactagggtt tgacacgact
     2881 tatctgaagt tgttctccgc tatcatctta gctatttgtc tgatgatccc gcaattgaag
     2941 aaagcactga acttaaaaac gggttttgag aaggaggcat agtaatgact gatatattga
     3001 caatcaaaaa tggcagaaaa gtcgtaaaca atggaatgaa tgaagagaaa gtactattgg
     3061 atgaaattaa ccttacaatc agagaagggg acttcatcac tgtccttggc gggaatggtg
     3121 ctggaaaaag cacactgttc aatacgatcg ctggtacgct tcaactcagt caaggatcga
     3181 tctcttttaa agatcagctg atcacaaaag attcagaaga aaaaagagca cgattccttt
     3241 ctcgagtttt ccaagacccc aagatgggaa cggctcctcg gatgacagta gcagaaaatt
     3301 tgctacttgc acaaaaaaga ggtcaaaaac ggaaattccg tttacgtaac ttgaaaaatc
     3361 aaaaagaaga ttttttcaga ctatgtcaag aagtcggtaa tggcctagag caacacttgg
     3421 atactccagc gggtgaatta tctggtggtc aacgccaagc attaagcttg ctgatggcga
     3481 cgatcacagc tcctgagtta ctattattag atgaacatac tgcagcttta gatcctaaaa
     3541 cagctaaagc attaatgcga ttaacaaatc agcggatcaa tgaacaaaaa ttgacttgtc
     3601 tcatgatcac gcatcgaatg gaagacgcct tgaaatacgg aaatcgtctg atcgtactcc
     3661 aaaaagggaa aatcgttcaa gatatttctg aaaaagaaaa gcaacatttg acaatgggcg
     3721 accttttgca gttctttgaa gaagtagtgg attgatttcg acagaaaaat tcctttcagt
     3781 agaaggactt gaaaactcat tgacatcttc ctttgattca tcctatactt aaaacaataa
     3841 acaattaaac atatttgggt gttttgtagg atcacgtagt caatgatttt aacaattaaa
     3901 tagaatattc tttgctctga caagtaaacg atgagaaaag aatttgctac tttgccacct
     3961 agacgtttcg tactttttcg tatcaaacgc taagtggctt tttttattga agtaagaaca
     4021 aaggaggaat aagatgattt ctggacaaac caaattagct gggctctttg ctgatccggc
     4081 ttctcacagt ttatccccat tgatgcacaa tactgctttt gaagcaaaca acatcgatgc
     4141 ggtgtattta gctttccaag taaatccaat gaatttgaag caagcagtcg aaagtattcg
     4201 aacttttgat atgttaggtg taaatctttc gatgccgaat aaaacagcgg ttattcctta
     4261 tctggatgag gtaagccagg aagcgcaatt gatcggagca gtgaatacga tcgtgcacga
     4321 aaagggtcgt ttgattggct ataataccga tggtgcgggc ttcatgcaat ccgtgcaaga
     4381 agctgggatt tcgatcaaaa agaaaaaaat gactctactg ggagctggag gtgcagcaaa
     4441 ggcagtcact gttcaagctg cgttagacgg cgctgaggaa atcgtagttt ataaacgaaa
     4501 caaccaaaca ttcgctcaag taaaagaaac attcgaacaa ctcagctatc gaacttcttg
     4561 taagataaaa gttcgtgact ttgccgatac gcatcaatta agaaaagact tgaaagaaag
     4621 ctgtcttcta gtcaatgcaa cagatatcgg gatgggaaag aaaatcaatc agtcaccgct
     4681 cttagatata agcatgatgc atgagaatct agcggttttt gatttgattt atgcacctag
     4741 agaaacacgt ttattaaaag aagcaaaaaa agtaggagca aaaggataca atggacttgg
     4801 catgttgatc taccaaggag caatcgcgtt tgaattatgg acaaaggaaa agatgccgat
     4861 ccatgtgatt gaaaagctgt ttgattaaaa aaggataata gataaagatc ttttattctc
     4921 gcataaacgg tctcaagaaa agtaatcctt tatgtatcga agcatttatt tcgttatttt
     4981 ttattaaatt atcaaaaaat gataggcttt tgtcgattgg ttatcgtatc ctttatttat
     5041 cagtaagaaa cgaggaggaa ccacaatgag tcggatggat cgctataagg acatccataa
     5101 gaaggcgaaa cctctgaagc gggatacggg gagtattttt gctagaagag aacgaaaacg
     5161 aacgcgtatg gaaaatgagg aagatgctac ccgtatttat gaaagagagc agcattcatt
     5221 tgaacatttg aaccaatacg agcaacagat atacagagat gcaccaagag cagaagaaca
     5281 acaaaaaaat aaaaaatttt tcaatcggca aaagaagaac aaaccgttaa aacctcgaag
     5341 aaagcgatcg tggaaaaaaa tcattctatc gattttgctt gttttgatcc tttattcagg
     5401 tatctcattt tttattggta aatatgtagc tgaacatgac acaagcttag aggcagcgac
     5461 ttcagaaacc tttcatgggc aaaaagcgac gaatggtgcg cataatattt tgatccttgg
     5521 aagtgataca cgcggagaag atgccgggcg agccgatacg atcatggtct tacagttgga
     5581 tggtccttcc cataagccga aactgatttc ttttatgcgt gacagcttcg ttacgatccc
     5641 aggggtagga caaaataaga tcaattcagc ttatgcatac ggaggagccg atctagtgcg
     5701 tcaaacttta gtagaaaatt ttggaatcga ttgtcaatac tatgcgaaag tcgatttcaa
     5761 atcgtttgaa aaagtgatcg atgccttatt catgaacgga gtgaagatcg atgcagaaaa
     5821 agatctgaat ctggatggtg tagatattaa aaaaggggtc cagaagatgg atggacatgt
     5881 tcttttgcag tacgcacgtt tccgaatgga tgaacaagga gactttggcc gtgtcagacg
     5941 ccaacagcaa gtaatgaacg ctattttcag ccaattgaag aatccattga atctgatccg
     6001 tgcaccttat gcagctggta aagctttagg atatacatcc acagatgtca ctgcttggtt
     6061 cttgacgaaa aacctctttt cgattgcacg aggagctggt ggcattgatc gaataagtgt
     6121 gccagtagac ggttcgtgga attatgggca aagtgattat gctggcagta ttcttgaaat
     6181 tgataatcaa atgaatcaat ctgctattac agattttttg aataaatgat cataaaaaag
     6241 atcaagaaga agctgcgcaa ggcttttgtc atgaatcaat caaacgattc actcgtaaaa
     6301 aacgctttct tatggtagat ttaaccaaga gaggagctgt ttacattgga tatctatctg
     6361 aacttcaaaa atgagtcgcg tgaagccatc gctttttatg aaaaagtttt tcagactgaa
     6421 gcatcaggta tcaccacata cggtgaaatg cctggaatag aacaaatgaa cttgccagaa
     6481 gaagcaaaaa atctaatcac gaatgcacgg ctgaacattt atgatacatt agttatgttt
     6541 gcagatacgc cagaaggaat tggtcctgaa ttagttgtgg gaaataatgt ttctttagtc
     6601 atccagacaa gaaatgaaga agaaacgaag cgcctatttg aaagcttagc tgagggtggt
     6661 aagattgaga tgccactgga tgctgttccg tgggctcagt tgtatgggat ggtaactgat
     6721 cgatttggca tcaactggca gattaaccaa gagtgacagc taaagatgaa tattttctgg
     6781 aaacatcaag cagcaaacgg atcatcgttt gtttgcttga tgtttttgtg tctatttcga
     6841 ctatacggta tctttttttt attgccagat gcgaaaatat gttccataat agagaagtcc
     6901 gcaaaaaatt aagtaacgga ggtcagaaga tgaagacggt gatactagct gaaaaacctt
     6961 cacaagcaaa agcctatgcc gaaaccttcc aacagcaaaa gcggcatgaa gggtattatg
     7021 aaatcagcga tccattgttt gctggtgaag taaccatcac ttatggtttt ggacatttgg
     7081 tagatatggt tgctccagga gcttatgaag agcgttgggc aaaatggtct ttagaaaatt
     7141 tgcctatttt cccagaaacc ttccgttacg aagttccaat ggacaaacgt gcacaatttt
     7201 cgatcgtaaa acgagaattg cagtcagccg ataccatcat tattgcaaca gatggtgatc
     7261 gagaaggtga agccatcgcg tggtcgatta ttcgacaagc aaacgcattt tctaaggaaa
     7321 agaactattt acgtttatgg atcaattctc ttgaaaaaga agcaatctat gaaggtttta
     7381 agaatctcca acctggaaag aactattttc caaaatataa agaagcgcaa gcaaggcaga
     7441 acgctgattg gctgattgga atgaatggaa gtccattata tagcttgcta cttcaacgaa
     7501 aagggattga tggcagtttt tctcttggtc gtgtacaaac accgacactc tatatgattt
     7561 atcagctgca agaagaaatc aaacacttca aaaaagaaac gtactttgaa ggagaaggtt
     7621 taattacgac aaacaaaggg cagttttctg gaaaaatcgt accaaaaaaa gcatttaaaa
     7681 cccaagaaga gttaacgaag gaaatagaaa aacttggagc gcatttaggt aagcaaaacg
     7741 gacggattct tgaagttacg aaaaaggaaa agaggttgca tagtccacgt ttattttcgc
     7801 tatctagttt gcagacaaag atgaatcagc taatgaaagc aagtgccaaa gctacacttg
     7861 atgctgctca aggattgtac gaaagcaagt ttctaagcta tccaagaacg gattcctttt
     7921 acattacaga aaatgagcat cagtatctgg ttaaacatct gcaaaattat aaaaaatttt
     7981 taggaataga agaagtacag acaactgaga tcaaagcaaa gaaacgatat gtcgatgcga
     8041 aaaaagttca agaacatcat gcaattattc cgacaaagac gattccgact cctgcacgct
     8101 ttgcgaagct ttccaaatta cagcaagcaa tctatttgca agttttgcgc actactgtgg
     8161 ctatgtttgc tgcagattat atctacgaag agacgaccgt aatgacgggc gtacagcaat
     8221 taaagctaaa aagcatcgga aagatcccat tacagcaagg ttggcaggaa atcttacgca
     8281 tcaagtcaaa aaagaaagaa gctcagactc ttcctcctat cgtagaaaat gaagaagcag
     8341 aagtagaact gaaaagtatg gagaaagaaa cacaacctcc aaaaccctat accgaaggaa
     8401 cgttgatcac agcaatgaaa actgcgggaa aaacgctgga taatgatgaa gcgcaagaaa
     8461 ttctcaaaga agtagaagga atagggacag aagctacacg agccaatatc attgaaaatc
     8521 ttaagcagaa gcattacatc gaagtcaata aaaacgaaat aactgttacg ccaaaaggaa
     8581 tcactctttg taaggcagta gccaatgaac cattactgac gagcgcagaa atgactgcgc
     8641 gctgggaagg gtacttgaga aaaattggta aacaagaggg gacaccatct gtttttttag
     8701 agaatatcaa aaaattcatc ctacatttat tggcagaagt tcctaatcaa atcgacaagg
     8761 tagacttttc agatgagatt agcgggacac gtcagataaa agcgatggag aagaaaaacg
     8821 atcaattagg aagatgtcca aaatgtaaaa agggaatagt catgctttat cctaaaatcg
     8881 ctacatgctt gaatccggaa tgcgacttca aattgtggcc aacagtagct aaaaagaagc
     8941 tgactaaaac gaatctcaga gatttgcttt caaaaggaaa gacaagtaaa gttgtcaaag
     9001 gttttactgg taaaaaaggg aaattcgatg cagttttagt attaaaagaa gatatgacaa
     9061 tcggtttttc ttttccatgg atcgaaaaca gtggaacaaa agcagttgat ggaaacaaag
     9121 aaacatcaag aaaaaataat gaaaacgaag tagagtaaat gaaaacaatg aaatagcgga
     9181 atatttattc cgaaaagtga gaatataaat accaataaaa ctaaaaaata tcagtgaatc
     9241 aagcaaaaac gttggggtag gctgatttta tatagatagc aaggagtttt tttatttgaa
     9301 aaaagtgcat tcatttttaa attatcttat gggagcaatc acgattgtgg ctgtgtacca
     9361 agcatttcta aagtatcctg attacgggac gaagttgttg tcattgacgc acaatcaaac
     9421 agcatattca ccaacgttga ttttatcgac tttgactgca ggagctaaaa gcgctactta
     9481 tttttttcat aaaacgacaa gcatgctaaa gcgaaagaaa cagcgaaaac aattgttggt
     9541 ggtggtagcg gctatgatca ttatttattt tctaccagtt attacacaag tatttcatca
     9601 atattttggt taagaatacg agagtttgtg acaaaagtca tgtcacaaac ttttttcttt
     9661 gtcatttttt cgtaagaaaa agcaaaataa aagtatatac attgattaaa agtatatact
     9721 tggatataat gtacttacta tagaatgaga atggtataga gggtggcgaa atatgaaaaa
     9781 aatgaaaaag tataaaatta gaaaatctgg caatagcgat gtaacaacta tcccaccaga
     9841 agtaaaagaa ttcatgggtg tgcagacagg tgacgcaatc agttatgttt ttcaatctga
     9901 tggttctgta cgaatgatca aagcacaaga agaacctgat attgattcat tagttgattc
     9961 gatcatgaat caatatgaag acgcgttaaa agatttggtt gatttatgag gtatctttcg
    10021 actaaagaaa ttatcaaaat caacgcgaaa gttattttac gtcactcgcc aggcgaaatg
    10081 atcggtgtaa aagatgcaaa tgcattagat atggccgtca aacagccttc acaagcagta
    10141 ttcaatcaag aactctatcc tgaaatctat gaaaaagcgg cgattttagc aattaattta
    10201 gctaaaaaac atccttttca taatggcaat aaacgaactg ctcttgttgc catgttgttg
    10261 tttcttcaat tgaataattg tccagttgct ttttctcgtc aagaagctgt tgattttatc
    10321 ataatgatta ccactagttc attggatttc gattcactaa agtccaagat aaccagttat
    10381 ttacgacaaa ccgcaataaa atgaacgaat taaaaacttt atttctcaat tagatcagca
    10441 tgtcattaag gaatatgctg atttttttat gtttaatcat acaaaatagt tttttcataa
    10501 aaatatggaa aatatggatt aattttgaaa taattgattt aaaaggaata caaaagagtg
    10561 aatag
//
LOCUS       DAZAOD010000092        10341 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000092 DAZAOD010000000
VERSION     DAZAOD010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.094"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(78..563)
                     /locus_tag="ACHDPO_002329"
     CDS             complement(78..563)
                     /locus_tag="ACHDPO_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFN3369918.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    653..998
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1043..1684
                     /locus_tag="ACHDPO_002330"
     CDS             1043..1684
                     /locus_tag="ACHDPO_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFN3369919.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1703..2338
                     /locus_tag="ACHDPO_002331"
     CDS             1703..2338
                     /locus_tag="ACHDPO_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFN3369920.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2356..3171
                     /locus_tag="ACHDPO_002332"
     CDS             2356..3171
                     /locus_tag="ACHDPO_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFN3369921.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3490..4926
                     /locus_tag="ACHDPO_002333"
     CDS             3490..4926
                     /locus_tag="ACHDPO_002333"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFN3369922.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5115..7547
                     /locus_tag="ACHDPO_002334"
     CDS             5115..7547
                     /locus_tag="ACHDPO_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFN3369923.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            7777..8844
                     /gene="rlmN"
                     /locus_tag="ACHDPO_002335"
     CDS             7777..8844
                     /gene="rlmN"
                     /locus_tag="ACHDPO_002335"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFN3369924.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            8834..9040
                     /locus_tag="ACHDPO_002336"
     CDS             8834..9040
                     /locus_tag="ACHDPO_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369925.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(9037..10140)
                     /locus_tag="ACHDPO_002337"
     CDS             complement(9037..10140)
                     /locus_tag="ACHDPO_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFN3369926.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT         3418 a         1774 c         2255 g         2894 t
ORIGIN      
        1 aaaagaattt ctgatatatt ttgtgctaaa taaagaaaaa gacgcttgaa ttgggaaata
       61 agaaaactac tctatcatta caaattttca taaactggca gatgttctaa gtaaacaagt
      121 atcttttcaa agtcggaaaa atccataatc aacgtagtgg tattgatatt tggatgaaag
      181 cctacggtat cttgacgatc aatagcagca tcgatcacga cttggatttt tttctctttg
      241 tcgtgcatca atgctaatgg agtcactgta cctgctggaa cgcctaggag gtcaggaagc
      301 tgttcttcag aaacaaaaga taagcgcttt tcttttaatt gttcagctag ttgttttaaa
      361 tcggcgtgct tttcatcagg caagatgaca agatagattt gttttccttt tcttgatttc
      421 aataatagat tttttacttg cggaccaggt agggaaaaag ggacattttt gactgacgta
      481 atcgcaggat gatcgacttt ttgaaaagag atacccagtt tttttagtag ttcataagct
      541 tcttgttcgg ttgcacgact catcgcgcat caccctcctt tttttattag tgtatcataa
      601 aaaagagttg acaaatgaaa aataatcatg taaattacac gtaaagttaa aacaaatgac
      661 atcgaaaaga agagtagccg ttaggtgttt ttagagagtc tctggttggt ggaaagaggc
      721 agcagttaac cgtgaaacac atcttggagt cgattttctg aagcgtatag taggaaaatc
      781 cggggagccc gttacagctg cggtcgttgc tagatgacca gataaggctg gcttttccgt
      841 gaggagtcgg taaaaaaagg tggaaccacg tgattaacgt cctttgatct tcggatcaaa
      901 ggactttttg ttttcatctg aacggcaacg actgtgtgag gttttttctg caaggaaaaa
      961 ataaacagag gtggaaccac gtataatacg tcctcttggc atttgccaag aggatttttt
     1021 tattttaaag gaggaaaaga agatggagta tttgattgaa gttatgccgc aattattagt
     1081 aggagcactc acaacattga aattattttt atttaccttg attggctcat taccattagg
     1141 gattgtttta gcattaggat tgtctttgca ttttaagccg ctacgctact tgcttcaaac
     1201 atatgtatgg gttatgcggg gaacaccgct gttgttgcaa ctgattttta ttttttatgg
     1261 gttgccgacg attgggatcg tttttgatcg tttcgaagca gcactcattg cctttatctt
     1321 aaactatgca gcttattttg cagagatctt tcgtggaggg atacaatcga ttcctcaagg
     1381 tcaatatgaa gcagcgcaag ttttgcaatt aagtcccttt caaacggtga cgaaaatcgt
     1441 catcccacaa gtgacaaaga ttgttttacc ttctgtaggg aatgaagtta tcaacttggt
     1501 caaagattct tccttgatct atatattagg tttaggtgac gtaatgcgtg ctgggaaaat
     1561 cgcgatggaa cgcgacgcga ctttactgcc tttgctaggc gtggcaatca tctatcttac
     1621 attgactggt attctaacaa tcgtaatgaa acaagttgaa ggaaaattaa attattaccg
     1681 ctaactgata ggaggaagaa atatgattga attgaagaaa gtgaacaaag catttggtga
     1741 aaaaaaaata atcaaagatt tgaatctaat cattccagat gggaaaacat tagctatcgt
     1801 aggtccttcc ggtggcggta aaaccacgct tttacgtatc ttggctggct tagaaagttc
     1861 tgacagcgga gaattttatt tagacggtgt accgttcaac ccattcgagc ttaaaatgaa
     1921 agaacaagtt gtaggagtcg tattccaaga cttccagcta tttccacatc tgaatatttt
     1981 tgaaaacatt accttagcac caaaaatggt attgaaacag acaaaagaag aatacaccaa
     2041 aaaagcagaa gaattagcgg cttcattagg gattagtgat ttattgaata tctatcctta
     2101 tcagctttct ggcggacaaa aacagcgggt agcgattgcc agagcattgg ctatgaatcc
     2161 acgggtattg gcttatgatg aaccaacaag tgctttagat cctgaattac gccagcaagt
     2221 cgagcgtttg atcctatcat tgaaagaaga tggggtaacc caaattattg tcacccatga
     2281 tttagtattt gcagaaaatg tcggtgatca attactaaaa gtttccccaa ttcattaaga
     2341 aaggagaaga tagagatgaa aaaaaccagt tttctattcg ctttgatcgc aggtcttctt
     2401 ctttttgcag gctgttcgaa caaaaaaact tcagcagata attgggcgac tatcaacgaa
     2461 gagaaaaaaa tcgttatagg tttagacgat acatttgttc ctatgggatt tagagataaa
     2521 gacgggaagc tcacaggatt tgatattgat ttagccaaag cagtctttga acaatatggg
     2581 attacggtag actttcagcc cattgactgg tcaatgaagg aatttgaact gaacaatgga
     2641 acgatcgatt tgatatggaa cggctattcc aaaacgccgg caagagaaaa gaaagtgcaa
     2701 tttacaaaac cttatatgga aaacgatcaa gtgctgatca cacctaaaga atcaggaatc
     2761 acaaactttg gacaaatgaa taataagaga ttaggtgcgc aaaatgggtc atctggttat
     2821 gatgtattta cgaaacaacc agaagtatta aaagagatag tcaaaaacca agatgctgtt
     2881 ttgtatgata gttttaatga agcattgatc gatctgaaaa gcagacgggt cgatggtctg
     2941 ctgatggata aagtatacgc agactattat ttgaaacaaa gaaacgaact agaagacttc
     3001 aacataacaa aaggttctta tgagagtgag gattttgcag ttggtgcacg caagtcagat
     3061 agtacattag tgaaaaaaat caatgaagcc ctagatcaac tagagaaaac aggtgaattc
     3121 caaaaaatat ccgataaatg gtttggcgaa gatgttacgc cgagaaatta acaaataggg
     3181 gactgtgaca aaagacgtgt cacagtccct ttttccgaat aaacagtgtt ctcctgccaa
     3241 ctccttgtga ctcggagctg aatggcaggc tcacaacctc ttggtaaacg gtgttcaaaa
     3301 gccagttttt cggtattaag ccaaatttat gcaaaaatgt agaaagccat tttcacaaaa
     3361 tttttcttac tactcgaaac taagcgactt tttcacaacc tcctttacat aattttattt
     3421 tgttgtggaa ggggtttcgt gttattctaa aagaggaacg attgaaggtt ataggaaagg
     3481 aagagatgaa tggaacacaa agaacttacc tcatttccaa aagattttct gtggggctct
     3541 gcttctgcag cgtatcaagt agaaggagct tggcaagaag atgggaaagg agaatcagtc
     3601 tgggatcgat ttgtacggat acctggaaag acatttaaag gaacgaacgg tgatttggca
     3661 gtagaccact atcatcgtta taaagaagat attgctttaa tgaaagaaca aggtctgaaa
     3721 gcttaccgct tctctgtagc ttggacacgg atttttccta atggacgagg agaagtcaat
     3781 caagctgggc tcgcttttta tgagagattg atcgacgaat tgattgaaaa cgatattgaa
     3841 cctatgttga ctttatatca ttgggatctt ccacaagcat tgcaagatga atataatggt
     3901 tgggaatcac gtcagatcat tgaagatttc actcattatg cagaaacatt atttgaggca
     3961 ttccgcggga aagtccatta ctggattagt ttgaatgaac aaaatatctt cacttcatta
     4021 ggttatttgt tagcagcaca tccgccaggt gtgacagacc cgaaacgaat gtatgaagtt
     4081 aaccatattg ctaatttagc aaatgcatct gtcatcaata aatttcacga gttagaaatg
     4141 cctggaaaaa tcggaccaag ctttgcgtat acgccaaatt atccaattga cagtaatcct
     4201 gaaaatgttc tggctgctga aaatgcagaa gacctgatgg ccaattattg gatggatgtc
     4261 tatatgtggg gaaaatatcc gattgctgcc atgaggttct tagaagaaaa aggatgggca
     4321 ccaacgattg aagctggcga tgcagaattg ctagaatctg ctaaaccaga ttttcttggg
     4381 atcaattact atcaaacggc gacgaatgca ttcaatccat taaacggagt tggtgctgga
     4441 aaaatgaata cgacaggaaa aaaaagttca tcagaagaaa ctggagttcc tggaatgtat
     4501 aaaaaagttg agaatccatt tgtcgaacga acaaattggg actgggagat tgacccagaa
     4561 ggattaagga tcggactgcg tcgtatcaca agccgttacc gcatgccggt actgattacg
     4621 gaaaatggct taggagagta tgacaagttg acagaagata aacaaatcca tgacgactat
     4681 cgaatcaatt acttacaaag ccacgtcaaa gccatcaaag aagcaatttc ggatggagca
     4741 gaagtcctag gctattgcac ctggtcttat acagatttgc ttagctggct gaacggttat
     4801 caaaagcgat atggatttgt atatgttgat caagacgaaa cacaagaagg atctttggaa
     4861 cgatataaga aagacagtta ttactggtac caaaaactga ttgaagaaaa tggagagaac
     4921 ctttagttca catacttaaa acaagaaggt acggctggat atggccgtgc cttttcttga
     4981 taaaatcatt tagaaattaa gaaaaactgt aaaataagct gaaaaatgaa agaaagcgtc
     5041 agttctttca aacaaaactt tagttccctt actttttttt gtataatgaa acttgatgaa
     5101 atgagggata ataaatggca caaaagaaac ggcctactaa aaaaaggaaa aagacgaaaa
     5161 aaacgaaaaa gcaaaaacag cagcaggaac aaatgctgac gattggtgtt gggtttgcct
     5221 tgattttatt tgctgtcttc ggctttttaa aattaggttt tttaggaata ttgattgcaa
     5281 acggctttcg gatcattgca ggaaatactt accaaatcct ctgtctttta ttagccgtat
     5341 taggattttg gattgtcatt aagaatacag agttttcaat tggtaaaaac cgacgctggt
     5401 ttggcggcat actcttttat ttcggtatct tattattgtt acatgcccat ttatttggca
     5461 aactccatac tggggaacca aatatcatgg ggacgacatg ggatttgtta gccagtgata
     5521 taaaacaaag tcaagtagac aataacgttg gtggtgggat gattggagca atcctttatc
     5581 attttactta cttcttgatt gcacagcctg gaagttattt agcagcagtg ctattactgg
     5641 caggaggagc attcctgttc agtaatctgg aaggctatca gctgttaaat ggtatccaat
     5701 caattggaga acgagtacag gaattattgg aaggtgatcc tgccaagcaa gctcgaaagc
     5761 aagcggcaaa ggaagagaga atgaaacagc gcgcagaagc gaaagaagca aggcgcttag
     5821 ctgcaaaaga agctgcagaa tatgagaaga aaaaagcggt gagccagcaa agggaaaata
     5881 ctgctgatga atggcaggaa ccagaaaata cagagccgga gcagctaagt tttgttccaa
     5941 tcgacagttt tcaagaaaat atccatcctg cgaatctaga gaaaccagta ccagatacac
     6001 caaaacagac caatacagca gaaggttttt cagatgagtt gccagaggat gacggtacct
     6061 cattagaatt tgagattgaa gcagaacagg aaaatcaaga ctatgaatta ccgacagttg
     6121 atttgcttga ttctatacca actgtggatc aaagtgatga gtataaaaaa attgaaaaaa
     6181 atatcggcgt attagaacaa actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag
     6241 ccagcttagg accatccgtc acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa
     6301 gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga
     6361 tggaagcacc gattccaggt aaatcactga ttggtattga agtaccaaat ggaaagatca
     6421 gtatggtttc ctttagagaa atcatcgaag cacaaccaaa ccacccagat aaattactag
     6481 aagtaccttt aggacgtgat gtttctggac gggtacaaac ggctgatctt tcgaagatgc
     6541 ctcacttact cgtggctggt tcgactggta gtgggaagtc agtagcaatt aatgggatta
     6601 tcacaagtat attaatgcgt gctaagcccc atgaagtaaa actgatgatg atcgatccga
     6661 aaatggttga attgaatatg tacaacggca tacctcatct gttgacgccg gtcgtgacga
     6721 accctagaaa agcagcgcaa gccttacaaa aagtagtaca agaaatggaa gaacgatatg
     6781 aaaaattcgc ggcaaccgga gtaagaaata tttctggtta caatgaattt gttcaacaga
     6841 aaaacttgga aaacggaacg aaacatccaa ccttaccatt catcgtagtg atcgtagatg
     6901 aattagctga tttgatgatg gtagccagca atgaagttga agatgcgatt attcgtttag
     6961 cgcaaatggc tcgggcagcg gggattcata tgatcctagc tactcaacgt ccaagtgtgg
     7021 atgttatcac aggaatcatc aaagcaaatg taccttccag aatggcattt gcggtatcaa
     7081 gcggtacaga ttctcggacg atcattgatt ctaatggggc agaaaagctc ttagggcgag
     7141 gagatatgct attcttgcca atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca
     7201 tttctgacca cgaagtagaa cgggtcgttc aatttgttac agatcagcaa gaagctcatt
     7261 atgaagagaa aatgatgccg acagatgaag ttgaaacgac aggtgctcca gaacagccac
     7321 aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt
     7381 cccttctcca aagaagattt cggatcggtt acaaccgagc agcacgttta gtagatgaac
     7441 tggaagctca tggagttgtt ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg
     7501 agcaggaaga aacatcagaa acgttgccgg acgataatga catgtaaaac ttgtgtgatg
     7561 aagggttgaa aaacgaataa ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa
     7621 tggttttttt ccatcttttc taatacggta tgatgtcttg tctttttagt ttttgtgaga
     7681 ttaaagttct attcgattta tttgtgaagt attgcattaa ggaaatgaat catgtatagt
     7741 atgtagcgaa actttgagaa aaagagggaa aatactttgg aaaaacagtc catttatggc
     7801 ttgacgaatg aagaattaat caattggttt atagaaaacg gcgagaaaaa attccgagct
     7861 gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat
     7921 ctatcgaaac aattgatcga aaaattatcg gagcatttta tcatcaatcc tctaaaacag
     7981 atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt tgtttgaact ccctgataaa
     8041 aacatgattg agactgtact gatgagacaa gaatatggct tgtcagtttg tgtgacgaca
     8101 caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt
     8161 gatctgactg ctggagaaat tgttgcacag atcatgatgg tccaacatta ttttgatgag
     8221 cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg ggatcggtga gccatttgat
     8281 aattacgaca atgtaatgga ctttttgcat atcatcaatg atgccaaagg attggcaatt
     8341 ggtgctcggc acattacagt ttccactagt ggattagcac acaaaatcaa ggaattcgct
     8401 aataacggct tgcaagtcaa tctggctatt tccttgcacg cgccgaataa tgaggtgcga
     8461 acatcgatca tgcggatcaa ccgaagtttc ccaattgaga aattgatgga agctgtggat
     8521 gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta
     8581 aatgatagac cagagcatgc gcaacaatta gcagatctat taaaagataa gaaaaaatta
     8641 gcatatgtca acttgattcc atataatcca gtcagtgaac atgatcaata ttctcgcagt
     8701 ccaaaagctg atgtattgag attttatgat gtattgaaga aaaacggcgt aaactgtgtg
     8761 atacgtaaag aacatggtac agatattgat gcagcttgcg gacaattgcg aagcaagcaa
     8821 atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt ttttcaatta ccataaaagg
     8881 agcagttttc ttaattaagg aactgttcaa cttaaataag agaaaagatt ctatagcgaa
     8941 agctataaag ctttttttga caagaaaaac cctcatcaag caaagaaatg tcctcaattt
     9001 gatgacagcc tgcttgatgg gggttttagc aattatttaa ctgattttct tatatccttg
     9061 ctggctttct tgtgtagcat gataagtttc tacgtcaaga atggcctgtt taaatttttc
     9121 tcgggtgatt tcataaggca catgtttaat atcatttgtt gccatggctt tatctaagat
     9181 tgcttctaaa tcggtcgtga cattgagatt catgtcggtt aacgatactg gaagttggtt
     9241 ctttttcata aacacataga ttttatcaaa caaatcgaac tgctgatcca tcatcaataa
     9301 ggtcagtaca ccataactga cagatgctcc gtgaaggtat ccctccattt tttctagaac
     9361 agtcgtaccg taatagaatg agtgtgccat agcagaatta tagttattgt taactaaaac
     9421 agaaaccaat ccggtagtaa caatgatatc cgaaacgact tgttcaattg catatgaggg
     9481 acgatcgtcg gcactatctt tcaatgcttg cgtaccataa gtcaagagac gatcaatgca
     9541 catttttccg atttggattc ctaatctatc cgtgtagcct agatcatcgc cacgagcaga
     9601 aaaagtagat tcgacttctt tggataaagc atcgccaata cctgcccata agtatttatc
     9661 aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa
     9721 gaagagtccg tccattacgc cttcttcgtt atagatgaca cataccgcag tgacgggcga
     9781 acagttcgaa ccaatagtgg gaaaggtgaa gactggttta gctagttttt caccaatgac
     9841 ttttacagta tcgcaagcac ggccaccacc gactgcaaac aggacgtctg ctttttggac
     9901 actttcatgc tggatcaact gttcaatatt tccataagtt gaattacccc cgtaccagag
     9961 actggcgaca acctctattt cctgtgtcaa agctactttt attttgtttt ctgcctttga
    10021 aagtgcagtc ttccctccaa tcagcactac ttttgtccca tattctttga cgattccatt
    10081 tgctttttca tacgcatctg ttccaatggt ataatttggt aagaaaacac tttgactcat
    10141 attcatttcc ttctttcttc gttgaaacgg gttaaaattt taaagagtga tcgatctgac
    10201 tgcggctgta gatggagtag aggtgaacct aagacaggat aagtgatgaa taaggtggca
    10261 tgaacacctt gaaatcatca ataagtatcc taaaaacgaa caagtacaaa aacattgaaa
    10321 acgacaataa tgaatttttg t
//
LOCUS       DAZAOD010000093        10150 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000093 DAZAOD010000000
VERSION     DAZAOD010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.095"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            423..692
                     /gene="rpsN"
                     /locus_tag="ACHDPO_002338"
     CDS             423..692
                     /gene="rpsN"
                     /locus_tag="ACHDPO_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFN3369927.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            707..886
                     /gene="rpmF"
                     /locus_tag="ACHDPO_002339"
     CDS             707..886
                     /gene="rpmF"
                     /locus_tag="ACHDPO_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFN3369928.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            918..1295
                     /locus_tag="ACHDPO_002340"
     CDS             918..1295
                     /locus_tag="ACHDPO_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369929.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1316..1465
                     /gene="rpmG"
                     /locus_tag="ACHDPO_002341"
     CDS             1316..1465
                     /gene="rpmG"
                     /locus_tag="ACHDPO_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFN3369930.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1489..2472
                     /locus_tag="ACHDPO_002342"
     CDS             1489..2472
                     /locus_tag="ACHDPO_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFN3369931.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2502..2624
                     /locus_tag="ACHDPO_002343"
     CDS             2502..2624
                     /locus_tag="ACHDPO_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFN3369932.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            2642..4165
                     /locus_tag="ACHDPO_002344"
     CDS             2642..4165
                     /locus_tag="ACHDPO_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFN3369933.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            4189..4428
                     /locus_tag="ACHDPO_002345"
     CDS             4189..4428
                     /locus_tag="ACHDPO_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3369934.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4621..5082)
                     /locus_tag="ACHDPO_002346"
     CDS             complement(4621..5082)
                     /locus_tag="ACHDPO_002346"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFN3369935.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5277..5495)
                     /locus_tag="ACHDPO_002347"
     CDS             complement(5277..5495)
                     /locus_tag="ACHDPO_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3369936.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5613..7229
                     /locus_tag="ACHDPO_002348"
     CDS             5613..7229
                     /locus_tag="ACHDPO_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFN3369937.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(7470..8810)
                     /locus_tag="ACHDPO_002349"
                     /pseudo
     CDS             complement(7470..8810)
                     /locus_tag="ACHDPO_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9248..9394)
                     /locus_tag="ACHDPO_002350"
     CDS             complement(9248..9394)
                     /locus_tag="ACHDPO_002350"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369938.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            complement(9433..9627)
                     /locus_tag="ACHDPO_002351"
     CDS             complement(9433..9627)
                     /locus_tag="ACHDPO_002351"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFN3369939.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            complement(9537..9869)
                     /locus_tag="ACHDPO_002352"
     CDS             complement(9537..9869)
                     /locus_tag="ACHDPO_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFN3369940.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
BASE COUNT         3377 a         1608 c         2004 g         3161 t
ORIGIN      
        1 aaagaatcag tatgattgaa ttagttcact taatgtctat tcttataata taaggaataa
       61 tcaaagtttt aaaaaattgg cgataaacca gttaaacata aaagattgaa taaaaagtta
      121 tagtttcttt catattgccg ttttaagtag aggaaaagct acttaaaacg gtatttgtgt
      181 ttgattggac taataaaagt gaattcttat ttttcagagc ctaaactgca tattctttta
      241 aatgatttga ttatctctat gtaccgataa attcgttttc aaatagttat ctattcatat
      301 gagttttatt tcatgttatt tattgttgac aagagcaact cttgttggta aagtatcagt
      361 gtcaaaacgt aacgattacg atttgaggtg tctaaatcaa aataaaagga gtataaaggt
      421 atatggcaaa aaagtcgaaa attgctaaag caaagaaaca aatggcgatg attgaaaagt
      481 atgcagataa acgtcaggaa ttaaaagccg caggagatcg caccgctctc gctaaattgc
      541 caagagattc aaatccgaat cgtctgaggc ttcgtgatca gacggatggt cgtccaagag
      601 ggtatatgcg aaagttcggt atgtcccgta ttaagtttag agaacttgcc catcaagggt
      661 tgattcctgg agtaaaaaaa gcaagttggt aaaaggagga aatatcatgg cagtaccagc
      721 aagaaaaaca tctaaggcga agaaacggtt aagaagaact catcaaactg tagtaaaacc
      781 agaaatttca tttgacgaag cgaatggtga ttatagacgt agccatcatg tatctttaaa
      841 agggtactat aatggaaaga aagtaattaa aggagcttca aaatagttta atatataact
      901 tttaggaggg aatcaaaatg gaaattattt acccaccttt agttgaagaa ggattaaagt
      961 attatcttga aacgacccag caatcgctag ataaatgcac tttttatcgt tcgatggtag
     1021 agagaggaat tattactgaa acgggtttac cgacccaaca ggcaattgaa aatggattag
     1081 tcaaagatta ctatgaggac caaggcttat catttgatga ttttttaaga atctatccaa
     1141 tttttgaaga gtatgacgag gagttatttc aatgtatcga tggttattgg gagatacctg
     1201 ttgatatgaa agaaaattta gtttcacaat tggaatctgg cgagttaact tttgaagatg
     1261 cacaacaaat tcaagcatat cttgaagatc gataagtatt gaaggaggaa gatttatgcg
     1321 tcaaaatatt attttggaat gtgtcgaaac tggagaacgt ctgtatctca ccagcaaaaa
     1381 taaacggaat aaccctgaac ggttagaatt aaaaaagtat tcgccaaaat tgcgcagacg
     1441 ggcaattttt aaagaagtga aatagctaag tggtaaaaag gtgacaaaat gggcatacca
     1501 gttacaatcg tttctgggtt tttaggggct ggaaaaacaa cgctaatcaa tcaagccttg
     1561 caagtctcac cctaccccag ggaagaaatt attataattg aaaatgagtt tggtgaagtt
     1621 gggattgatc acaaattatt agttcatagc gaggaacggg tgttacaact aaataatgga
     1681 tgtatgtgtt gcagtcttcg cagtgattta ttagcaatat tgatttcttt actggaaaca
     1741 atagaagaac atcaacaacc aatttcacaa atcatcattg aaactacagg tatagcagat
     1801 ccccaaccaa tcattcaaac acttttaaca gcgcctcaac taagaggaag agtatatatc
     1861 gatagtttat tgactgttat tgatagtgac agttttgaac ttattgaaag agaaccacaa
     1921 gcccttaagc aacttgtcat ggcagatcgc atttttgtgt ctagaaaaca aaacttgaat
     1981 ttatctgcac taaaaaaatt acagagagaa atcaaaagta ttaacccttt atccgatatt
     2041 cgaatgttca cacatagtga aacgattcaa aaaaaggatt tttataattt gaaaaaattt
     2101 aatcatccct tagtttttga aagtgattca tcagaaaatc actataatgg caaatactat
     2161 catcaacacc atcaagtaca tgagtttaaa tcaattctct taacttcaga tcaagacata
     2221 aaaaaagatt ttttactcca atggattgac tggctgattt taaccaacca agggagcctg
     2281 tatcgtttta aaggattgat tgctttacaa gagcaggatt ttatagttgc catgcaagag
     2341 gtaaacgaac aggttaattt tcaatacacc actcgacaaa aagaccaaac cactattatt
     2401 ctaatcggaa aaatgttgga tgaagaaagg atcaaacaga gttttgataa attactggcg
     2461 gaaagcaaat aatgataagt agtgattggg ggtaatttct aatggagaaa acggatatat
     2521 ctagtgcata tcgacgactt aaaagcccga atattaaaac tagaaaaagg gcattaaaaa
     2581 ttatcaaaga acataaacga aataaaatga agaaattagc ataattaagg aaggaaaaag
     2641 aatgaagaaa atcagtgtag gacttattgg gatagcagct ctaggattat tgggagcttg
     2701 ctccagcact aatgatgcaa aagtatcgaa tgataaagat ggaaaattag aaattgtaac
     2761 aacattctat ccaatgtatg atttcaccaa aaacatcgtc ggcgatgaag cgaacgtgga
     2821 tttaatggtt ccagcgggat cagaacctca tgactatgag ccctcagcta aggatatggc
     2881 aaaagctcat gatgctgatg tttttgtata tcataacgaa aacatggaat catgggtacc
     2941 aaaagctaaa gaaagttgga agaaagctgg gcctaatgta gtagaaggaa caaaagacat
     3001 gattttattg ccaggtagtg aagaagaaga tcatgatcac ggagaagaag atcaccatca
     3061 tgaactagat cctcatacgt gggtttcacc caaaatggca attaaggaag tttcaaatat
     3121 caaggatcag ttagttaaat tgtatccgaa aaaagcaaaa gtatttgaga caaatgctga
     3181 aaagtatttg actaaactga aacggttgga tgctgactat accactagtc ttaaagaagc
     3241 gaaacaaaaa agttttgtga cgcaacacgc agcctttgga tatttagctt tggattatgg
     3301 attgaaacaa gttcctattg ctggactaag tcctgaagaa gagccatctt ctggtcgatt
     3361 agctgaatta aaagagtatg ttaaaaaaaa taagatcaat tatatttact ttgaaaagaa
     3421 tgctaatgat aaaattgcaa aaactttggc caacgaagct gggataaaat tggaagtact
     3481 gaatcctctt gaaagtctta caaaagaaca aatggataat ggtgaagatt atgtttcagt
     3541 aatggaagac aatctaaaag cgttagaaaa aacaactatg gttgctggtg aagaggtagt
     3601 tccagaaaaa gaagcgaagg atgaaaagac agttgctaat gggtacttta aagatgccga
     3661 tgtgaaggat cgcgaattga gtgattatac aggcgaatgg caatctgttt atccgttgtt
     3721 aaaagatgga attttggatg aagttttcga ttacaaagca aaaatcaata aagacatgac
     3781 agctgccgag tacaaagatt attatactac tggctataag acagatattg atactatcaa
     3841 cattaaagac aacaccattg attttgtagt caacggtgaa catcatcaat acacatacaa
     3901 atatgttgga tacaaaattt tgaattatga aaaaggaaac cgtggtgttc gttttaattt
     3961 tgaaactgat gatgcaggtg ctggtcgttt taaatatatt caatttagtg atcatggaat
     4021 tgcaccaagt aaggcagagc atttccatat tttctttggt ggagaaagtc aagaaaaact
     4081 ctataatgaa ttgcataatt ggcctacttt ctatccagct tcattgtcta aacatgaaat
     4141 tgctcaagaa atgatggctc attaaaattc aatttttgga ggaaatacat ggtaagaaaa
     4201 gtattattgt ctatggattc caagaatatt gatgcttatc ggcgttatcg atttgcaaag
     4261 caaatgagat taaatgggag tacattagct gatattgctg caactttaca tgttagtatt
     4321 gacacagttc atagagtatt aaaacgggat cctgattgtt gttttatcaa ggtcaatact
     4381 ggaagaagta gacgtttagc aaaacggcat aatagcttgg ccaattaatt gataatacca
     4441 gagtagatca tttttccctt atttggattt gatctgcttt ttattatgtc ttgaattgtc
     4501 aaatcaagcg caacacttta tcaaagaaga cttcataagg tgttctccaa tctaaacact
     4561 ttctaggtct gttattcagt ttttcaatca tctgatttat cgttgagtta tctaccgtag
     4621 ctatctcttt cgattttggc aagtattctc gaatgagtct attcgtattt taatttgttc
     4681 attgttgcca agggcatgag gatctggaaa ataaaagggc atattattca atgcttctgt
     4741 aactgcgaaa tgattggaga attcttttcc tctatctgga gtgatcgttt tgaccgcctc
     4801 atttggaata ctgcttaaaa gttcaatcat tttctcgctc acataagcgg ctttctttct
     4861 ggggaccttc tttcctgcta aaaggaagca tgattttctg tctgtcaaag tcactaaaca
     4921 agtaccacca gttttgccag ctacaatatc ggctttccaa tgaccaaaat cacttctatc
     4981 atctgcggat tttggacggc catggatcga atgagtaagg caaatctttc cacgagactc
     5041 gacatgattt tttgtatgtc ttgtttttcc tcgatggtgc aatgaacgga tcaggccttt
     5101 attgccgtgt gagaggggtt ctgtatcgaa aagatcattg caaattgcac gttagatcgt
     5161 gataaaacta attgaaaagt ccatatgttc atgcttcaaa cgattcgaga tttcctctgg
     5221 cgaccactga aaatcgacaa ataaatgacg aacaattgac caaactcacg gatcatttag
     5281 aatgtgataa cgtccgcatt tttttcttcg ataagcataa tttttttccg ctttggaagg
     5341 tgaatagttt ttttcttgtt tcttctcagt tcatgtaaaa tagtaaacgg gctatgctga
     5401 atgtcgttgc caattatact aatagaaaat ccttcttcgt gaagcagaaa gattctttct
     5461 cgttcgagta tagtaagatg acgatactgg ctcataatta ttttccttct aggagtgttc
     5521 tcgacaaact tatactagtt ggatatcgat tatgactcat ttttatgtgt tgcacttaaa
     5581 gtgtaaattc aaggtataga aagaggttcc ctatgaaaaa aatacctatt acaatcttaa
     5641 ctggctatct tggttcagga aaaacgatac ttctaaatca tattctgtac ggtgatcacg
     5701 gaaagaaaat tgctgtcatt gtaaatgaca taggggaagt aaatgttgat ggggtattag
     5761 tcgacaagaa aggttttaaa agaactggag aaaaacttgt ttcgatgccg aatggatgca
     5821 tttgttgtac attacgcgaa gatttgattg ttgaactaga tcaattagtg caattttctg
     5881 acttgaatca aattgttatt gaagcttcag gaatcagcaa accaattcca attattcaag
     5941 caattatatt agctaaaaac cctttagaca ttgatttgac ccaacgatta gagattggtg
     6001 ccattattat agtagtggat gtaaaacgtt tttgggataa tttcgaaacg ggtgaaaaga
     6061 ttcaggaaag aaaagctgaa ggtaatgtag ttgaagaaga acaggatatt cgtggcttgt
     6121 taattgatca attcgagtgt tgtaacatat tacttttaaa taatagtgac ttagtgtcaa
     6181 ccaagacgat ttacaaaatt aacggtctaa ttgctaagtt acagtccaat gccaaaataa
     6241 ttaggacaat taaaggtgaa gtagacttat cgaaaattct aaatacaaat ctttttaata
     6301 tagatgagac ttcctattca gtgggctggt tcaaagagtt agagcttggc tatcaaaatc
     6361 atattcctga aacagaagaa tatggtatct caagttttat ctatcgaaat cggttactcc
     6421 ttgacgcaca aaaatttgcc catcttacgg ataaaaattt tcctggcaat attacaagag
     6481 caaaagggtt tctttggttt gcccaacata gtgatttttc gacgatcttt gaaacatcgg
     6541 gtagctataa aagtattgaa tcattaaatt attgggtagc tagtttacct aaaattgagt
     6601 gtcaaatgat tatacaaaaa aatcccgaat tgaaggaagc ctggcatccg ttgtttggtg
     6661 aacgcattaa taaactagtt tttattggta tgaagatgga tcaacaatgt attaaggaac
     6721 aacttgaggg ttgtttaact gattctctta atgcagataa tttccgaaaa atttcaccat
     6781 ttccatggaa aaagtctaat atgtttagcc agatatcgtt aatgaaattt ttaagaaaag
     6841 ctggtgtcaa gataggcgat gtcataatta ttggcatttt gattattacc tcttttattc
     6901 ccttatttgt attctctata gaaaaggaga atgaaacaac tgaagatgct atcaaatatg
     6961 ccatcgttcg aattgatggc aaggaaatgg atcgcttcga tttggataag atcaatcata
     7021 aactcgtgaa ttatcatcct gcgaagggac aatataatat tgttgagatt aaagatggaa
     7081 gaattcgagt taaagaagat aatagtcctg atcaaatcgc ggttagaact ggatggatct
     7141 caaaacccgg tcaaacgagt atttgtttac cccataagtt agttattagt attgagaaaa
     7201 aagaaagcac agattactac atttactaat ctggaaatag atgaggaggt ttttaataag
     7261 aaaaagatat tattattaat aatagcaggg gctttattaa gtgtgttaag cgcttgtgga
     7321 caagaaaaag aagcggtgac aacaggcaca agtatcttta acgggacctg caatggttta
     7381 gttaacagtc ggttagatta cttattttgg ctcttcgtca atgagtgttg gtgaagaaat
     7441 tcaatagaat aatcgagata ctcacacggc tagacagcta tcttgtctag ccgtgttgtt
     7501 gttctggctt tagtcagttg ggtagtattc ttagttttct taaaatattt tcctcgatat
     7561 aaaaagattc gttctcggta gttttgaaag tttctatagc cataggcaat tcgttttagt
     7621 actttgatat ggttattcaa acattctata gggccgttgg aatagggaac gcgcaacgct
     7681 cgtttgattt ctgtttggta tttcttgaag gtcgtgaaca ctggttggta gtgctctggc
     7741 aactccttgt agtcttcttt taggagcgcg acgaattcag gaacatcttg tcttctgata
     7801 acggaaagaa aatcctggta gacttcgtag cctcgcttta aggaatcatc ataagataat
     7861 agccgatcga ctatctctgc ttctgtcaga tgatctcgaa atgacggacg ccagtagcga
     7921 tgctgacctt tcaattccca cgcattcttt tgaagtagtt tccagtattt ctttaagtgc
     7981 ttcgaccgac gatccccttt tttaaaggtc ttcattactt gaattcggtg gttggtaaaa
     8041 gcccgaccaa tgtgttggct aatatgaaag cgatcggcga cgattcgggc attcggaaaa
     8101 cactctttca ccaatgtgcg atagggtgta tagaaatctg aaaccactag acgcacttgt
     8161 tcacggactt ttatagggta gcgcaagaaa tagtcgcgta aaggattgag ttgccgattt
     8221 tccacaatat caatcagttg atgggtcttg ccgtccatca tgacaaagct catggctccc
     8281 gagacatttt tcactgattt gaattcatcg aaacacacca cttctggtaa cagctggctc
     8341 aaagaaatgg ttttaggccg aaggctgcga agtattcgaa tgacagtggt cggagaaatg
     8401 tgcttcatac gtgcgatcaa agacatagaa agaggttcgc ttaatagctc aagaatggct
     8461 tgtttgactc tgcgagcaat ggagcagcga cgatcactaa ctgaatcttc tgctaaaaaa
     8521 gtctttccac agtgtttaca tttgaagcgc tgtttgttaa tccgcagaat ggtcttgtag
     8581 ttactgacat cattcaataa gatggatact tttttccagc cctatttaat gatcgtttgt
     8641 tcattttgat agtggcgatg aaagcattcc tccggttgat aggtcaatgt gccatcaaaa
     8701 acaaaacatg tttcgtcatt gattcgctct ttgcgaaagg catcttcatg aaagataaga
     8761 tttaggtcta gaatatctag taactctttg gtaaactctg aataggacat cttgaaacac
     8821 tcctttgaat ggttttcgtc gactttattc taaaggattt taaggtgtct gtttgcgttt
     8881 attagaaaaa agaaaaagta ttggcaacag aaggcgtcac caacactaga tattatagat
     8941 cccttatttt cttcgcttca aattgtcaag gagtcatcat aaattttgta tggattcttt
     9001 tgtttgggta gtagtcttct aaataatctt ggattaacac cttcatctct attttacttt
     9061 tatatttgtt ggagtcgatt aattctcatt tgattgatcg atgaaacgct tcaattactg
     9121 cattgtcaac aggagtccca gtttggctca ctgaatgtgt gatgtggtgg tcgttcaaca
     9181 gctcttgata aataaaagac cgatgctggc tacctctatc ggaatgaatt accgtaggca
     9241 attctcctta ataaatttgt aatggacgga cgacaatctc ttttttcatg tgtgaatcta
     9301 ccatatagta acgtagaata cgagttgcta agtcaatata ggtggacaaa tagaggcgac
     9361 cgtcattaca tggaatgtaa gtaatatcca tcacccaaac agcatcaatt tggttctgtt
     9421 caaattatcg attcaacatt tttttaccat ttctttgatt gttttttctc taccatgaga
     9481 agatttgcgt cgatgaaatc ctcttgtgca taaattcatt tcacgcataa gaacagctac
     9541 aacacgttta ttgatttcga ttccttcatc gtaaagtttt tgagtgatcc ctggagatcc
     9601 gtatcgatct ttgtgttcgt agaacactcg tcttcctctt ttagtcgttt attttcctgt
     9661 tcaagaatgt agaaatctgc tttatcaggt aatctttttc cttgtccagc aaaagcattt
     9721 ttcccgtatc gacgatattc tgaaacccat cgggaaattg ttggacgaga gatattgtat
     9781 tcttcagcaa ttttcttggt agttactttt ttctcaagga tatcctgtga aatctttagt
     9841 ttaaatttac gatcatatgt ttttctcaat agagttcatt ccttccggta acgtaactga
     9901 tagtcaagaa aagtgtatca tagcccaact tagtatcagg gtttgtcaac taaactgtgg
     9961 aagttgatag ataagagttt ttaacaacca aaattctctt gactattttt gaaatcagac
    10021 aaattttgat tggacacata gttgaataaa tctaccgtcg ttacggaagg taaatcgcat
    10081 gcttttcaat tctagaggag aagtcctcgt tgaagtacca tagcccagtt ctggattcga
    10141 cctcctgccc
//
LOCUS       DAZAOD010000094         9935 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000094 DAZAOD010000000
VERSION     DAZAOD010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.096"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            32..388
                     /locus_tag="ACHDPO_002353"
     CDS             32..388
                     /locus_tag="ACHDPO_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HFN3369941.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            404..754
                     /locus_tag="ACHDPO_002354"
     CDS             404..754
                     /locus_tag="ACHDPO_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HFN3369942.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            783..1562
                     /locus_tag="ACHDPO_002355"
     CDS             783..1562
                     /locus_tag="ACHDPO_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HFN3369943.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1573..2235
                     /locus_tag="ACHDPO_002356"
     CDS             1573..2235
                     /locus_tag="ACHDPO_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HFN3369944.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAIFPA
                     VN"
     gene            2254..3360
                     /locus_tag="ACHDPO_002357"
     CDS             2254..3360
                     /locus_tag="ACHDPO_002357"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HFN3369945.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3350..4441
                     /locus_tag="ACHDPO_002358"
     CDS             3350..4441
                     /locus_tag="ACHDPO_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HFN3369946.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4454..5194
                     /locus_tag="ACHDPO_002359"
     CDS             4454..5194
                     /locus_tag="ACHDPO_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HFN3369947.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
     gene            5482..7422
                     /locus_tag="ACHDPO_002360"
     CDS             5482..7422
                     /locus_tag="ACHDPO_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFN3369948.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            7509..9431
                     /locus_tag="ACHDPO_002361"
     CDS             7509..9431
                     /locus_tag="ACHDPO_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFN3369949.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(9711..>9935)
                     /locus_tag="ACHDPO_002362"
     CDS             complement(9711..>9935)
                     /locus_tag="ACHDPO_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HFN3369950.1"
                     /translation="DRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDLKDPAQAVG
                     SEEEILTEFRKVREGIKRKVLDLNQRTSIV"
BASE COUNT         3242 a         1649 c         2207 g         2837 t
ORIGIN      
        1 acaaatgata ttttacgagg aggaaacaat catgattaaa gtagttattg cagaccgtat
       61 gggtaaagga caaaatgtgg ccaaaggggt agaagcagct ggtggaaaag cagttgtcgt
      121 accaggaatg ggggcagata tgcgtttggg cgatgtgatg caacaagagc atgcagatat
      181 gggtatctct ttttgtggta gtggtggtgc aggtgcatta acagcagcaa caaaatatgg
      241 ctatccagaa cgacatggta tgcgttcgat tgaagaaggg atcacagcta tcaaggatgg
      301 caaaactgtt ctaggtttcg gctttatgga tcaagaggaa ttagggaaac gtctgacaga
      361 agaatttatc aaaaagcatg gaaaatagaa agagggacat gaaatgagcg ttcaaaagac
      421 aattcagcaa aaagttatcg tctccggtaa aggggaaaca aagcaacatg cttttgcatc
      481 agcgttagca gaaattcaaa acaaaataat ggaacaatca aacgtattat tgcgaatcga
      541 accagtcaat gtggatattt taaaggcggt cgaaaacaaa tacacagaac gctttctatt
      601 tttcttcttc ccacggcaac gtattagcta tgaagtcgaa ctctctgtta ctgtggctgt
      661 aacagaaata aaattggcag acatatcgtt cagccagcaa atgactgaag atccaaatgg
      721 gattgccatt ccatttgtaa ctaaaaaaat ctaattttga atcataaggg ggaaagaata
      781 acgtggattt cgtaatcatt ctagtcaaat cggtcattat cgggggatta cttggttttg
      841 cagcatctgt cggggcagct cgaatgtttc atgcacctaa tacacaaggt ttaggagctt
      901 ttagaacatt aggcgaaatg aatgcctgca tgggtgatcc agcttctcat ttttcatttg
      961 gtttaggctt tttctttaat gcatgggctt cttcagttgg tgctggtgca ttcacacaag
     1021 atgtgacgca tcgaatcatt cccaattggg cagcggcagc acttctagca aaaaacaaag
     1081 atgtcaccca gaccatgcat gatccgaaaa aaatggggat cattggagcg gttatcgggg
     1141 cagtggtggt agccttctta aacacaacag ctgcagcaat tccagaggcg ttacaagtga
     1201 cggcggtttc cgttttggta ccagcagcga cgattctgat caatacagta atgccagtta
     1261 ttttttggtt ggcagcttta gacgcaggga aacgaactgg tttttggggc actctttttg
     1321 gtggtatcgc gcaattgatt atgggaaatg cggtacctgg tgttgttcta ggaatcttga
     1381 ttggtaaagg cgtcgatgag agcggttgga atcgcgtcac gaagagcatg atgatcgcta
     1441 ttgttttatt atttattttc agtggatttt tccgtggatt tgatatggaa atgatcaaga
     1501 gcttccagct tcaagtgcct aattggcttg ataacttgca caacatcttt agtgtgaaat
     1561 aggaggagaa tcatggagac aacagaagaa caagcaaaag tattagaagc aaagcggcaa
     1621 aagagctttt ggtttgcaga ctggtctttt ccgctaatcg taggaattat gtccgctgct
     1681 gtatttgcag gaacacacat gtatgtgatg tatggtgtgg gtgcattcaa tgaagtttcg
     1741 atcgtggcga tgttaaaagc cgggctggat ggcggatcct atggcgcagc ggcagcgttt
     1801 ggtgctagtt tcttatttgc cagaatttta gaaggctctt tagttgggat cttggactta
     1861 ggcggttcga tcctaactgg gatcggaatt ggggtaccag caattctctt aagtatgaaa
     1921 atagcggcac caatcgataa ttttgcactc tctttattga ctggtttggt tctaggtttg
     1981 attgttggtg gcatcattgt cttgattcgt aaatttacga tcaatcaatc aaattccact
     2041 tttggtgctg acgtcatgat gggggcagga aattcatctg gacgtttttt gggtccatta
     2101 attatattaa gcgcgtgtgc agcatctatt ccaatcggca ttggcgctac attaggagca
     2161 ctaggattct atgcttggaa aaaaccaatt gctggaggtg ctattttagg agcaatcttc
     2221 ccggcagtaa attaatagaa agagggtcat taaatgtttg atactttgat taaaaatgga
     2281 aggttagttg atggatctaa aatagaggtc gctatagaaa aaggcatgat taaagcagtt
     2341 gcagcagaaa taaatcagcc ggcgcaagaa gtagttgact tggagggaaa gtattattta
     2401 tccgctgggt ggatcgatga tcatgtccac tgctatgaaa agatgaatct ttattatgac
     2461 tatcctgatc agataggggt cgaaaaaggt gtgacgacgg tcattgatgc tggaactacg
     2521 ggagcagaaa acatccgtga attttatcaa ttgacgaaat cggtcaagac aaatgtgtat
     2581 gcgctaatga atatctctaa atggggcatt gtcaaacaag atgaacttgc tgatctaaca
     2641 aagattcaag aagatctagt aagtactgcg ttagcagaac tgccggaatt tattgtcggg
     2701 attaaagcga gaatgagtaa gacagttgtt ggtgaaaatg gcattaagcc attagaatta
     2761 gctaaaaaaa tccagacaga aaacaatgat ctgccattga tggttcatat cggttctgca
     2821 cctcctgagt tagaagaagt attgtcaaga atggaaagag gcgatgtatt gacccattgt
     2881 tttaatggaa aaccaaacgg tattttagat ccaaagacag atcaaattaa aaactttgtc
     2941 tgggatgctt acaataatgg tgtcgtcttt gatattggac atgggacgga tagctttaat
     3001 ttccatgtgg cagaaaccgc actaaaagca ggaatgaaag ctacctctat tagtacggat
     3061 atctacatcc gcaatcgtac aaatggccca gtttttgatc tagcaactac tttagaaaaa
     3121 ttgagggtag tcggctattc ttgggaagaa atcattgaaa aagttacagc agttcctgca
     3181 cggaattttc atttgaagaa taagggccag ttagctgtca attatgatgc agatttgacg
     3241 atatttgaga ttgttgaaaa tgaaaaggaa ttgaaagatt ccaacggatt tacacgtata
     3301 gctaaagaac aaattttacc gattaaaaca attattggag gcgtcatata tgacaattag
     3361 ctatggaaag tttgatttaa aagaagtcat taatgcatcg ggaaaaatga cgatcctagg
     3421 ggtttctaag gtatctgaaa gtgtcctagc agcacaacga tttggaggcg agcatttttt
     3481 tgagatgagt gatcttgcca tcaaaaccgg cgcttatctt tctcaattac tgaaagtgga
     3541 agatgcgcaa atcgtttctt ctgcttcagc agggattgct caatctgttg ctgctttaat
     3601 cggacagggc gacatgtacc atgtctatca tccctataca gaaaaaatcg ctagacggga
     3661 aatcatcata cctaagggac ataatgtaga ttatgggaca ccggttgaag taatggttgc
     3721 tcaaggtgga ggaaaagtca tagaagctgg ctatgcaaat atgtgtacac cggaacatgt
     3781 ttccatgatg attacggaaa aaactgctgc gcttctatat attaaaagtc atcatgcagt
     3841 tcagaaaagt atgctgacgg tggcagaaat ggtagaagtt gccaaagctc atcgtttgcc
     3901 attgatcgtt gatgcagctg cggaagaaga tttattcaaa tatagcgaaa tgggcgttga
     3961 cttagtgatt tactctgggg caaaagcaat cgaaggtccg agtgccggac tggtcatagg
     4021 aaaaaagaag tatattcaat ggattcggct acagtctaaa ggtattggcc gagcaatgaa
     4081 aatcggtaaa gataatattt taggctttac ccaggcacta gaagattatt taaaaaatgg
     4141 gagcgaatcc ggtgactcca tgaagcaacg attagcgcct tttgttaacg caatcaatca
     4201 acttcctgac ctttcagcga aaatagttca agatggtgcc ggcagagata tttatcgagc
     4261 aagtgtaacg attaatggcg ataaaagtgc gaaagaagtc attcaggaat taaaagcacg
     4321 aaatccagca gtctacaccc gagaatatca agcaaataac ggaatcattg agttcgacat
     4381 tcgttccgtc agccaaaacg aaatggaaaa aattataaaa agattgagag aaatcatgta
     4441 ggaggctttt aaattgtcag ttatcccaaa ttattataaa aatcgtgtat gtttaaatgt
     4501 attagctcat tcagttgaaa atgcaaaagc atgctatgaa gcagcggaag ggcatgtcgt
     4561 actaggtgtg ctatcgaaaa attatgctag cgatgaagca gcaatcgaag atatgaaaag
     4621 gtaccaagac gcaaccaata atgcgttgtc agttggatta ggcgctggag atccaaacca
     4681 aagtcagatg gtttcgcgtt tatctggggt tttacaacca caacatgtca atcaagtatt
     4741 tactggcgtg gggacttctc gtgctttatt gggccaaaat gatacagtca tcaatggatt
     4801 ggtttcacca acaggtaaga tcggctatgt caatattgct acaggtccgt taagttcaca
     4861 agcgccagca gctgaagtgc ctattgaaac tgccattcaa atgctgcaag acatgggagg
     4921 tacttcaatc aagtatttcc cgatgaaagg cttagcacat agggaagaat ttaaagcagt
     4981 tgcggaagct tgcgcaaaat atgaattcta tttagagcca acaggaggaa ttgatctttc
     5041 aaactttgaa gaaattctga aaattgcaat cgatgcaggt gtaaaaaaag tgattcctca
     5101 tgtttatagt tcaattatag ataaagaaac aggagatacg cgtataggag acgtaaagat
     5161 actattaagc atggtaaaaa aaattattca ctaactcatt agaaaataag aagcttattc
     5221 cagaatgaaa ttaaatggaa taagcttttt ataattaatt acggaaattg ttaatgtaga
     5281 taataattta gatgtacgta agcagaagta cagaaatgta agattttcca atattatttt
     5341 attcaacata ataaatcgta tatcaatttt tttagcgaaa tttctattta ttccaagaat
     5401 ttcagttatt acggaatcat tttgtgctta ataaaaagaa accgttttta tatactataa
     5461 atgtagaaag gcggtaggaa aatgaaaaaa attattgcaa tcacatcctg tccagttggt
     5521 attgcccata catacatggc agcagaaaac ttagagaaag cggggaaagc agttggcgcc
     5581 gaggtaaaag tcgaaacaca tggttccatc ggtattgaaa atgaattgac tgcaagagat
     5641 atcgaagaag cagctggtgt aatcatcgca gcagatacta aaatagataa atcacgattc
     5701 ggcggtaaac ctttgataac cgtaggtgtg caagaaggaa tccaccatgc agatgagttg
     5761 gtgagagata ttttagcagg aaaagcgcca gtctataaaa gtacggaggc aattatttct
     5821 tccgaaaata aaagtgaatc agaaaattta ggtaaaaaaa tctataagag tttgatgaat
     5881 ggcgtttcgt acatggtacc tttcgtagtt acaggagggt tattgatcgc gatttcttta
     5941 acattaggag gaacagctac acctgaaggg atcaagatac cagaaggaac gatttgggca
     6001 acgatgaata gtatcggaag tatcgctatg gggttgatgg ttccaattct atctgcattt
     6061 attgcgcaaa gtattgcaga tcgtccagga cttgttcctg gatttgttgg tgggatgtta
     6121 gcggcaaacg gagcattata tggtagtgat gcgaatgcgg gattcttagg cgggatcatc
     6181 actggatttt tagcaggatt cattgcttta ggaatcaaga aagtgcgagt accgaaagct
     6241 ttacaatcga tcatgccaat tattgttatc ccaattttag gatcattggc agttggtttt
     6301 gtgtttatct atgttattgg agaaccagta gctcttctat ttagttcatt gactcacttt
     6361 ttagcaggga tgcaaggagg aagtgaaatt gttctagcta tgatcttagg agcgatgatt
     6421 gcttttgata tgggggggcc gttcaataaa gtagcctttt tgttcggatc tggcttgatt
     6481 gcagaaggca attattccat tatggggcca attgctgtag ctatctgtat ccctccatta
     6541 gcattggggc tggcatcatt gattttaaaa accaaattta cgaaaacaga acgagaagct
     6601 ggtaaggcgt ccttagcaat gggactgttt gggattacag aaggcgctat tccgtttgct
     6661 tcaacagatc cactacgggt gattccaagc attgtaatcg gggcaatgac aggaagtgtg
     6721 atcgcgatgc tttcaggagt gacagatcat gtagctcatg gcggtccgat cgtagcggtt
     6781 ttaggagcag tggatcacgt agccatgttt tttgtagcag tgattgctgg tattgctgta
     6841 accgtgctaa tgttaagaat ccttaaaccg acattacaac aaactgcggt tgctgcagca
     6901 aatggtgtga cagtagcaga tctatcagag actgaaacaa gtgatgttta tacgaaaact
     6961 gaaacttttg attctatcac ggatattatg tcagatgaag caatcgtttt aggtgaaaca
     7021 gcaacaacaa aagacggagt aatcgaagat ttagtccaac gtttagaaaa aacagcggcg
     7081 atcacagata aaaccagatt taaagaagtc atctatgata gagaacatga aagtacaacg
     7141 ggaatcggta tggggattgc tattccacat ggaaaatcag cttatgttct taaaccaaca
     7201 gtggcatttg ccagaagtca atctggggta gattggcatt ctttagatgg aaaacctgca
     7261 catatgatct ttatgattgc tgtacctgaa aacagccaag gtgatatgca cttgaaaata
     7321 ctgcaacgtc tatcacgtaa attgatggat gatgacttcc gtcaagcact gatggaagcg
     7381 ccagataaaa caacagttca ccaattatta agcgaaatgt aacataagat gaaaaatcga
     7441 ccgtgatgag acataataga tgtgttatca tgatcgattt tttatttaga agggagtttc
     7501 tgcacattat gaatcagcgt cagcaatctt tgatctatca attaagtgag aacaataatt
     7561 atataacaac aaaaaagcta gcagagcatt tccatgtgtc agaaagaacg attcatagcg
     7621 atttgaatac cattgaaact tggttgagag acaaacatct gcctttaatg tttgaaagaa
     7681 aaaaaggtac aggtatcttg ttgaatggtc tgcctcacga aagggaacaa ctgaaacgag
     7741 cgcttaatga agagactcaa acagaaatgg ataaaaaaca gcttcgtcag ttattgattt
     7801 tccatctgct agtagcaaaa gacggattta gtcttgaaga actttcagaa aaactatatg
     7861 ttggaaaacg tacgattcgt aaagaattga cagagttgca aagctttttt gagtatcacc
     7921 atttacagct agtatccaaa acaaaactag gaacttttct taaaggcgat gaacaagaaa
     7981 aaagacagtt gcttgttaag acattacgaa atatgcagaa agaagatcca caaagtccgt
     8041 cgttgaaaga attcttcgct aaagatacat taaaagttat ccaacataca ttacaagatg
     8101 ttttttatga aaaccattta gaacagccga atggactggc tagtgtggag attcacatct
     8161 actttatgct cgagcgaatg aaacagtacc agaaagtgaa attaagtaaa gacgaaaacg
     8221 aagtcgtgga acacacccaa gcacaaaagt taagtagtca aatattagca aaactagcca
     8281 ccatctatcc aattgaattt tctcctgatg aaatcaatta tctggctttg cgtatcgcca
     8341 atctttttac aaattcacaa gcagccacac gttttcaaaa ggaatctagc gcacttgctg
     8401 atcatttgat cgaacaagtg gaacagtttc taggctattc attaaaagaa gatcagctac
     8461 taaaacaaaa tttaaggtct catttatctt caacttattt tcgactccat tatggtttgc
     8521 agatttctaa tccattgacg aaaaatgtgt ttagtacgta cacacaactt ttcttagttt
     8581 tacagttaat tttagaagat tattttgaaa aggaaaattt ttatgttcca caagaggaga
     8641 cagcttattt aacgatccat ttccaagcag cgatcgagcg acacaaacat cagaaaagta
     8701 gaagatatca aacggtttta gttagtgaat attcaaaagc tatggctact tttctcgaag
     8761 cacggctgaa cagagaactt ccagaattaa cgattatgga tctagttgaa tataagccag
     8821 aattaaagag acaagatttt ccctctgttg attttatctt ggctacgtta ccatttaaac
     8881 atataagcat tccagtaatc gagatctcac caatgatcac agaaactgat ctagcctatt
     8941 tgacaaaata tatgctggag catgtgccta tcaagaagaa aaaaacattt gatctagcaa
     9001 gctttactca tccatttctg atctttcctc aacttgaacg gacagaccca gccgatattt
     9061 taaactttat gggaaacgtc ttagtggaac atcattatgt ggagccggaa ttcatcgatt
     9121 ctgtcttgga aagagacagt cactccagta ctagagtagc accatttgta acaatccctc
     9181 acggtaatcc gctgtatgtg aagcattcga tgatttctat tgctacaatg aaagaaccag
     9241 tcctatggca cggggaacag atacgtatcg tactgctatt agcaataaag aaaaatgatt
     9301 tgaaacatgc agagttcaaa aaaatatttt ctgttattca ctatctagaa aagcagccag
     9361 aacaaatggc tcagttgatg caatccaatc atccgctaga aatcttaacg ttgttatcta
     9421 gttatgaata agtagcgatt aaaaaactgc ctttatattt ataataattc tatctattta
     9481 tttggaagta gaaaactaaa tacaaaaaaa gaggatgtgg ccaaagttgt ggcacatcct
     9541 tttattttga gtttcttata attttttata gttgcttacg atgtcttgac tactggtaaa
     9601 cggtgttcaa gagacaattt gtcggcaata aggcacaatt ttgtaaaata tggaaagcta
     9661 tttttttaac attgtttctt agtgcttgaa aaatcatttt gaatacttct ttatacgatc
     9721 gatgtacgtt gatttaagtc taaaactttt cttttgattc cttctctgac ttttctgaat
     9781 tccgttaata tttcttcttc gctcccgaca gcttgtgcag gatcttttag gtcccagtga
     9841 aggtgttcgt gattgtttgg aacggcaggg cacttgtctt tggcatcacc acaaagtgta
     9901 atgatcaagt ctgcctgagt aaagtaatct ctatc
//
LOCUS       DAZAOD010000095         9900 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000095 DAZAOD010000000
VERSION     DAZAOD010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.097"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(121..1005)
                     /locus_tag="ACHDPO_002363"
     CDS             complement(121..1005)
                     /locus_tag="ACHDPO_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFN3369951.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(1092..1991)
                     /locus_tag="ACHDPO_002364"
     CDS             complement(1092..1991)
                     /locus_tag="ACHDPO_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFN3369952.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            complement(2008..2514)
                     /locus_tag="ACHDPO_002365"
     CDS             complement(2008..2514)
                     /locus_tag="ACHDPO_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFN3369953.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            complement(2703..3323)
                     /gene="rpoE"
                     /locus_tag="ACHDPO_002366"
     CDS             complement(2703..3323)
                     /gene="rpoE"
                     /locus_tag="ACHDPO_002366"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFN3369954.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            complement(3399..3836)
                     /locus_tag="ACHDPO_002367"
     CDS             complement(3399..3836)
                     /locus_tag="ACHDPO_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFN3369955.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            3999..4829
                     /locus_tag="ACHDPO_002368"
     CDS             3999..4829
                     /locus_tag="ACHDPO_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFN3369956.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            4813..6180
                     /locus_tag="ACHDPO_002369"
     CDS             4813..6180
                     /locus_tag="ACHDPO_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFN3369957.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            6199..7008
                     /gene="yidA"
                     /locus_tag="ACHDPO_002370"
     CDS             6199..7008
                     /gene="yidA"
                     /locus_tag="ACHDPO_002370"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFN3369958.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(7051..7494)
                     /locus_tag="ACHDPO_002371"
     CDS             complement(7051..7494)
                     /locus_tag="ACHDPO_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFN3369959.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            7628..7999
                     /locus_tag="ACHDPO_002372"
     CDS             7628..7999
                     /locus_tag="ACHDPO_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFN3369960.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            complement(8168..8950)
                     /locus_tag="ACHDPO_002373"
     CDS             complement(8168..8950)
                     /locus_tag="ACHDPO_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFN3369961.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(8947..>9900)
                     /locus_tag="ACHDPO_002374"
     CDS             complement(8947..>9900)
                     /locus_tag="ACHDPO_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFN3369962.1"
                     /translation="EEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEILPDGKGK
                     NMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKALINANAV
                     TWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVYDILEER
                     RNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVREDAHINAV
                     GTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGTLGELVS
                     EKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
BASE COUNT         2870 a         2030 c         1753 g         3247 t
ORIGIN      
        1 aaaattggtg gacagttttt tgttgtacct gtatagatat tgttaagcct ttgcaagtaa
       61 ggtagttatg tgttcaacta cttattaaaa tgtgttattt attaaagata cttgtctcac
      121 ttactgaact ggccgatgat cgtttctgcc ataatagttc tcgacagccg ttggatgccc
      181 taataaatcc ccaactgtcg tgatgcgata cccttgctct ttcagataat cgatcacttg
      241 aggaacggca cgaatcgttt caggatagat atcatggaat aaaataattg ccccatcgta
      301 tactgttgct tggatcttct gcaaaatcaa atcaggattt cttgtcttcc aatcttctga
      361 atcaacagac cattcgatga tcggtcgctg gatgatcgtt gctcctacat tcgtgacaga
      421 accatagggc ggacgaacaa aagtgggggt tttgccagtg acttttttga tctcagtgtc
      481 tgctttcgtc acttcctccg tcatcgactg ggcagaaaga gtggccagat tctgatgatc
      541 gtatgtgtga ttgccaatct cgtgccctgc ttcagctgtc tgcttcacga tttcaggatg
      601 ctgcgccgta ttttctccta agacgaaaaa agtggcatgc acgttttttt cttttaagat
      661 tcgcagaagc tgcggtgttg tggtcgctcc tggtccatca tcaaagctga ttgcgacgct
      721 tttgacagcc ggatctcggc tcgtttttgt actgtcttgt gttgattgtg atgactgact
      781 ttgtaccttt tccgctgatt cttgaatggc ttctttgacg ttagctgttt cagttgattg
      841 gcttttaatg gttgattgtt ctgattgttt gaaagattgt gacgaatgct ccgaagagtg
      901 tgtttgtcct tttacttcgg tgatcaagga ggccaccgaa gtaatttcga aaaacaaaag
      961 cacggataaa gcaataatac tgataactaa ataatttctt ttcactatat ctcttctttc
     1021 tctttttctc ttcttattat ttacttgtac ttacttgaaa attgaaactg ctagtcgcaa
     1081 ctacttctcg tctaatgatc caaataatct tccgatgcca aaatcgtttt tgtcacggac
     1141 ttaggaatga caaattctgg tgtacccata taaccaggag caatttcgta ttgagaaaaa
     1201 gtcaaaacta attgatgctc tttgttcaaa taaaaacttc gtgtaggcgt aacaagtgtt
     1261 ggtttttcta tcgtcccttc ttgaatatct tgctcagtcc aatagtactt agatggatct
     1321 tccttgactt gttcggccat ctgccgtttg acttcttttg tcaaaacaga tagataggtg
     1381 tcatctttga ataaaagtgg aagtgagagc tggacactgt ttttcttgtc gattgtgtcg
     1441 tatctttttt caacatggct atctgctgct gtttgggtga tctgcctttc aatcacgaga
     1501 aaccggttat cgtctacgat tttctgataa tctcccaaaa cttggtaatg atccgtttca
     1561 aaatttccat attctttttc agctttttca aaatctgctt gtccttcgcg aaagtatttt
     1621 tgatttaatc catgaattgt tttattttct ttctcatttt gtgtattgat cttcggtacc
     1681 tgaatatcga ttttttcaga tcgatcagta aagcgttcgc ctaagatcaa ttcaatgact
     1741 gatcctaaga tgggtaaatc ttctgcaaag cttcgaactt gactattaaa aagaaggcta
     1801 cttgttgtaa tcattacgat agccaaagat actccgaacc cttggagacg tctctttctc
     1861 cgctttgctt ttataaatga ttgctcttcg ataataaaac gctggcggat ctcctcttta
     1921 agccctttgg gaattgcttg ttctttataa gttttcttta gtttttttaa attttctttt
     1981 tgggaataca tggcactctt ctctccttca ttctaggatt tgacgtaaag cattcaatga
     2041 gcggtacatt ttcgttttaa ctgtgttttc attcatatcc aagatagtcg caatttcttt
     2101 caaacgaaat ccttcaaaaa agtagaggat cagaatctct ttttccggac tgtctatttt
     2161 atctaaaatc atatggagct ctgcaacgga agtttctaaa ggtaactgtt gggggatatc
     2221 ttgaatttca aataagtcca caggcgtcct tttttgtctg cgccaactat ctaatgccgt
     2281 gcggatcaat atccgataaa accatgcact aaaatgctcg atctcttttt ctttttcaaa
     2341 atagttcagg gctttatgaa aactatcttg catcacatct aaggcctctt ctttatcatg
     2401 tacgtaattc atcgtgatac ggaacatttt ttgataatca gtttcgatga gtccattcag
     2461 caggtgacgg tatttttcga tctgccgttt tttcttatat ccagtaaaaa tcattctcca
     2521 ctcctttctg cctcacttaa tatgacgtac aaggtgcgct aaaagtttca atttttttat
     2581 tttttatgta tttacttggg atttttatat acaaaaaaga aggtgtgaca aaaatcgtgt
     2641 cacacctcct tattctgata ggctgatcgt ctctgtcaca acctctcgta agaaaataat
     2701 gtttattctt tttcagagtc agaaaattct tcctcttcat aatcttcatc atcatcgtct
     2761 tcgtctatga tacttaaatc ttcttcgata tttcctggca agtcttcttc atcatctgtc
     2821 gggtcatctg ctccgatttc ttgcaagtca gaattataag cagcgatttc ttcatcttca
     2881 tcatcatcgt catcaaacag atcatcgtca tcttcttctg tcagatctgt atcttctggg
     2941 tcatcgtcat tgtaatcgat cgcgtcttca tcatcattga taaaggcgtt gactttcttg
     3001 cgtttacggc gacgtggagt atcttcatcc tcttcgtcca ttccatggtt tacttcttca
     3061 tcgatcgaat cgatagcata ccatgaacgc aagccccaac gattatcccc taatgagata
     3121 aagctgccgt caatattcaa gtcagtataa aattgtgcga gtgaatcacg aatttcactg
     3181 tctgatttcc caagatagtt ttggatctgg ttagctaaat cagaaaaatc catgacatcg
     3241 ccacgttgtt ctaagatcgc gtgtgctact tcgatcattg ataattcgct tttgtttgca
     3301 ccttcaaata cactaatttc caatcaggac acgtcctttc acagtctact ccttatcata
     3361 caaaatcaga cacaaaaaat caaacttttc ttttatattt acgctgtaaa atccaaggtc
     3421 aaataatatt cgccgatttt ttccggtccc atgaacagat cataatcgat tcgaaccttc
     3481 cctgctgtgg gacggtcttt caaactaaca tgcagttctt tcgtaaaagt agcaatctgg
     3541 atcataccgt atggtgttcg ataggatgtt tctaaccgtt ctttatagcc aaatttcaaa
     3601 cgcatccgca tttctcctgc acggatcagc tgtacatgac catctggaac taatttgatc
     3661 gttacaggaa tctcatcgcc cgtctcctcc tgaatctctt tataacgtat gtacagcgta
     3721 tcgccaattg tcaccatttg ccctttcaaa tcaaaataaa aatcttgcac ttccccttgc
     3781 tgttttactt ttgtacgcaa tttgattgaa atcggtgttc cttgtgataa ttccattatt
     3841 cattctcctt tacttctcat agctacattg ttcctagttt cttttgtttt gtcaaccaac
     3901 ttgtccattt ttacagaaaa ccttttttcc aaaacaactc tttgatttta gagtataata
     3961 ttgtagaaaa tatgaattta tacaaaggag ccggttgaat gaaccctgcg attcgactag
     4021 atcagcacat ttatcaaaaa aacgactttt ccccttttgc attaacagat atattaacgg
     4081 aatattctaa agaacaccag caaatctttt tacatttctg gcaatatgac tgcacagtca
     4141 tcttaggtat gaaggatgtt cgaactcctt ttctaagtga cgggatccaa acactggaag
     4201 atgcaggtta cgctccagtg atcagaaatt caggtggatt agggatcgta tcagatgaag
     4261 gaattttgaa tatttctttg attttccccc aaagtgacac aaaaaaaata accatagatg
     4321 acgcttacga gcaaatgctc ctattgacta aatacgcttt tccaaaggca ccgatacaag
     4381 cattcgaaat cacccattct tattgtcctg gaacttatga tttaagcatc catggcaaaa
     4441 aatttgccgg tatcgctcag cgtcggatca aaaatgggat ttctgttatg atgtacttaa
     4501 gtgtcaacgg taatcaggaa aaacgtgggc aagtcatgaa gcgattttat caatctgctt
     4561 taaaagaaga ctttggtaca aatggctatc ctgcagtgga tcctgctaca atggcaacac
     4621 ttgaagaact gcttgaccaa cccctttttg taaaagaagt caaagaagca tttgcaaaag
     4681 cttttgaaaa gctgtattct gcaagtgatt tacaggattc taccgactgg ctaaaaaaag
     4741 aaatccagct ggagcaatgg aacaaccaaa tccagagaat ggaacaacgt aataacataa
     4801 aggagctaca ttatgacaac cccttataaa tatcaaatgc tgcctatgga aaaagttttt
     4861 cgtgatccag tccataacta tatccatgtc cagcatcaag taatcttaga tttgatcaat
     4921 tcgaaagaag tccaacgtct acgacgcatt aaacaattag gcacttcttc tttcactttt
     4981 cacggagcag aacatagccg ttttactcat tcattaggcg tttatgagat ttcaagacga
     5041 atctgcgata tcttttctcg aaatttttca aaagaaaaaa taggcaacgg aggctgggat
     5101 gatcaggaac ggctggtgac tttatgtgcg gcactgttgc atgatgtcgg tcatggtcct
     5161 tactctcata catttgaaca tatcttccat acgaatcatg aagccatcac tgtagagatc
     5221 atcacttctc cagaaacaga agtgtatcag attcttaacc gagtagaaga aggttttcct
     5281 gaaaaggtag ctagtgtgat ccaaaaaact taccccaacc cacaagttgt ccaaatgatt
     5341 tctagtcaga tcgatgcaga tcgaatggac tatttgcttc gggatgctta tttcactgga
     5401 acagaatatg gaacatttga tcttacccga atattacgtg tgattcgtcc ttatgaaggc
     5461 gggatcgctt tttccatgag tggcatgcat gcagtggaag attatatcgt tagccgatat
     5521 caaatgtatg tgcaagtgta cttccatcct gtttcccgtg gtatggaagt aattttggag
     5581 catctgcttc atcgcgcaca cgagttgtat caagaagatg ccagcagttt tgaactccat
     5641 tctcaattac ttctgccatt tcttgacgga agctttactt tagaagaata cctcaaactt
     5701 gatgatgggg tcttgggcac ttactttact caatggtctg aatctgctga tcctatttta
     5761 aatgatttag ctaaacgttt tttgaatcgt aaaccactga aatctgctac tttttctggc
     5821 aaccgggatt caaaattagt ccaagaactc actttgttag tagaaaaggt cggatataat
     5881 cctgtttatt acactgctgt gaattctagc tacgatctac cttatgattt ttatcgccca
     5941 gaacaaggca gacatcgcac acaaatcgag attttgcgaa atgacggaac tttgatagaa
     6001 ttatcacagg ttagtcagct tgttgctgca ttagcgggac aagaacaagg agatgagcga
     6061 tttttctttc caaaagaaat ggttgatccg tccttgcgtg atcattatga tttatttgac
     6121 gaaacttatc aagaatttgc cagccatatc cgtaatggcg cattgattga aataaattaa
     6181 aatatattgg aggaaattat gtctatcaaa ctagtcgcta tcgacatcga tggtacttta
     6241 ttaaatgaga aaagagaagt aacaaaagaa gtaaaagaag cgattgccgc tgctgttgca
     6301 aaaggtgttt cgatcgtttt atgcactggc cgtcccttac caggtgtcca ggaacagtta
     6361 aacgagttga acctttttca agataatgat tacgttatta cttataacgg ggcactcgta
     6421 caacaaacga aatcaggtaa aatcatcgcc cgtcacggac tgacacatga agatttccta
     6481 gagatcgaag taatggcacg ccgtgtcggc agtcatctcc attcgatcga tgacaaagcg
     6541 atctacacgc ctaatcgaga tatcagcgct tatacgatcc acgaagcaag tttagtcaag
     6601 atgccgctaa aatatcgaac acctgaagaa atgacaccag acatgaacat cgtcaaaatg
     6661 atgatgatcg acgaaccaga aattttagat gcagcaattg cgcgtttacc gcaaactttc
     6721 cgtgataaat acacaacggt caaaagtgcg ccctattact tcgaagtact aaataaagaa
     6781 gcaagtaaag gtgcggcagt tgcgaatctc gcacagcacc ttggtattga tcaagatgaa
     6841 atcatggcta tcggagataa cgagaacgac ttatccatga ttgaatatgc tggtctagga
     6901 gtagcaatgg gaaatgccgt ttctcttgtc aaagaagcag caaatgtcat cacttcatca
     6961 aacgacgagc acggtgtagc tgaagcaatc aaaaaatatg tactgtaata aataaaaaaa
     7021 ctgagagaaa gctgatctac tcgctttctt tcagttttta tttttttcga tccatctctc
     7081 gactgcccat cggtggctac cacgtttcaa tttcacaagc gcttcttgag ggctcaccca
     7141 ccaaatttta ttggtctttt cagttggttc tcctatacgc ttccaagaat cagcaacaaa
     7201 gaaatatcct ggattataat aataagttgc acgataattc gagtaaaaat actcatcagc
     7261 ttctcccaga taagaagaaa tttctgccac aattcccatt tcttctatca gctcacggac
     7321 aatcgcttct tctttcgtct cttctccttc aatttccccg ccaggaagaa aaaaagcacc
     7381 atttggagcc tcgattactg caatctgctg atctctttct atgacaatat atgctgcata
     7441 acgggtttga taatcagcaa attgcttttt ttcaccaaaa attggtttat ccatgaatag
     7501 tttccacctt aacagtttta ttttctatcc attttacatg agaaatttct catgaacaag
     7561 cacaaatcaa ctatttcctt acttcttttt gttatgattg agtaaaagga aaaggagaga
     7621 tgaatctatg aaaatggctc acacatgtgt tcgagtgaaa gatcttgaag catcaatcga
     7681 attttatcaa aaggcatttg gttttgaaga aagccgccgc cgtgattttc cagaaaacaa
     7741 atttacactt gtttatttga cacttcctgg ggatgactat gaattagagt tgacttacaa
     7801 ctatgatcat ggtgcgtatg atctaggaga cggctatggt catatcgcta tagcagctga
     7861 tgatctagaa aaattacacg agcaacataa agctgctggt cttgagatta ctgacttaaa
     7921 aggattacct ggcactgcgc cttcttacta ctttgtcatt gaccctgatg gttataaaat
     7981 cgaagtcatc cgaggatagt tagtatgggg cattttactc ttgattgaat aaaaaacaaa
     8041 caccaataat taaaatgaga cgcaaacttt tcattaaatt gaaaaagttt gcgtcttttt
     8101 ttaacaacca ttgtagctat aaggttgcca ctctccacca atttattttt aattcatttg
     8161 aaagaaatca aataaacgag gtacctttag aaaacaaaac tgcttttcct cctattatca
     8221 cacgatcttc ttttaattca cattctagat ccccgcccct tgatgacatt tgataagctg
     8281 acaattttgt tttattcatt ctttctgccc aataaggaat aagattagaa tgtgctgatc
     8341 cacatactgg atcttcattg attgttaatt ttggaaagaa ggttctagaa acaaagtctt
     8401 tttgcacact ttctgctgtc acgatgactc ctattcctaa ttcaaaattt ttgatagctg
     8461 taaaatctgg ctgcaattta gccaccgttt tttcatcttc taatacgaaa aataaatcac
     8521 gtgctaagta ggcttcttta atcttagccc caatcgcttc ttcatattca gacaatatcg
     8581 gcactttttt cggcataata ctaggaaaat ccatgtaata ataatcttta attcttgtca
     8641 caaatagatt accgctttga gtagaaaatt taatcgtttc atcaggtatt ttgtaatagt
     8701 taaataaaac aaatgctgtt gctaatgtcg cgtgaccaca aagatcgatt tctcgatctg
     8761 gcgtaaacca tctaagctca aattcttggt ttttcttcac tgtaaatgct gtttcagata
     8821 aattgttttc aatggcaatt ttttgcatcg taccttctgg cagccattct tctagcacat
     8881 aaaccgctgc tggatttcct ttgaacacct catctgcaaa tgcatcaact acgtaataat
     8941 ctaagttcat tttaaagccc ctttctctaa tttgttataa atatattctg cacaacaaag
     9001 atcttcaata gctagaccaa ctgcgtcgaa aatcgtcggc ctcgattctc ctttataaaa
     9061 tgtttttttc tcagaaacta attcgcctaa tgtaccaaca atacaagatt cctctaaatc
     9121 tccttctgcc atggctataa gcaggtcccc gctttctgtt aaggcagctg agtaatcatc
     9181 tacatagatt tgagaagttt ccatcaacga tgtacttatc tctcttgtat caggagtaaa
     9241 tgtgcccaca gcattgatat gtgcgtcttc ccttacccac tctttttgaa gaaatgcctc
     9301 tttactagag gtcaacgtac aaatgatttc cgctggacgt actgcatctt ctactgatat
     9361 tgcatttata aacgttattt taggatactg ttttttagct ttagcgataa aagtatttcg
     9421 tctttcttct aaaatatcgt aaacaaacac tgtagtgatg ggacgaatgg tagaaatcgc
     9481 agtcaaatgc gacaatgctt gttgaccagc tccaattaaa gcaagtgttt ctgcatgcgg
     9541 atttgctaag taatctgttg ccagcgcaga tacagcagct gttcgaatcc aggtgactgc
     9601 atttgcgttt atcaatgctt tgggtagtcc gttttgagca tcaaacaaga aaatctctcc
     9661 taaatgagaa ggtaaatgat actgatgatt atccggaaaa gcggtaatga cttttgtgcc
     9721 aaaatatctg ttctccccca aataagcagg catcatcgca aacatatttt tgccttttcc
     9781 gtcaggtaaa atttccacca atcgaggatt ttggctgatt ttaccacttt cataatcaaa
     9841 aaaacatttt ttcattactt gaatcgcttc ttcaaaacta aaagaagcta ctacttcctc
//
LOCUS       DAZAOD010000096         9779 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000096 DAZAOD010000000
VERSION     DAZAOD010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.098"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            364..1356
                     /locus_tag="ACHDPO_002375"
     CDS             364..1356
                     /locus_tag="ACHDPO_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369963.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            1372..2256
                     /locus_tag="ACHDPO_002376"
     CDS             1372..2256
                     /locus_tag="ACHDPO_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3369964.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            2305..3912
                     /locus_tag="ACHDPO_002377"
     CDS             2305..3912
                     /locus_tag="ACHDPO_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369965.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            3913..5397
                     /locus_tag="ACHDPO_002378"
     CDS             3913..5397
                     /locus_tag="ACHDPO_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFN3369966.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            5574..6566
                     /locus_tag="ACHDPO_002379"
     CDS             5574..6566
                     /locus_tag="ACHDPO_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3369967.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            6618..7487
                     /locus_tag="ACHDPO_002380"
     CDS             6618..7487
                     /locus_tag="ACHDPO_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005472675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFN3369968.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(7907..9520)
                     /gene="guaA"
                     /locus_tag="ACHDPO_002381"
     CDS             complement(7907..9520)
                     /gene="guaA"
                     /locus_tag="ACHDPO_002381"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFN3369969.1"
                     /translation="MRRTERAAYRTKFYSNLSSPTRFDEEPKIIVLDYGSQYNQLITR
                     RIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVL
                     GICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVT
                     QAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTG
                     DWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVL
                     LRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDE
                     ATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLF
                     KDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANA
                     GLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKI
                     SVRIVNEVAHVNRIVYDITSKPPATVEWE"
     gene            complement(9527..>9779)
                     /locus_tag="ACHDPO_002382"
     CDS             complement(9527..>9779)
                     /locus_tag="ACHDPO_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFN3369970.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         3045 a         1654 c         2111 g         2969 t
ORIGIN      
        1 gctaaataga ttaaacttac tggtgagtgg tcttgaacat acttttaaat cacattttac
       61 tgagttttat tggattttat aattcattgg aaacctcgta cttaatctgt ttttatctat
      121 cgactagaat ctgtatatat tccagctatc aatgaggccg cagaaaaggg tgcttaaaaa
      181 taatctgttg tttaaaatat tattatcaga atacttagat acaaaattct ggcacaaagt
      241 aaaaaaaata ttgacttaaa aaaatggata tggtaatcta taaacgaaaa tagtggtaac
      301 gtttccaaaa tgcatcttcg ttaaattttt atttttttaa acgaaaatgg aaacgtttct
      361 aaaatgtatt gggaggagat tgaattggaa aagacattgg gaccaggtgg tgagataagg
      421 gcggtacaac gggataaaaa aaatatttcg aagtgggaaa aattaaagaa acagttgcgg
      481 cgtgataagt ggatgtactt gttgctctta ccaggtatca tcatgacgtt tatctttaag
      541 tatgtgccaa tgtacggtgc tgtgattgca tttaaagact ataatcctat gctaggaatt
      601 ttggaaagtc cttgggtagg actagatcac tttagggaat ttatcagttc accaaatttt
      661 acgcttttgc tgagcaacac attaaaaatt agtatttatg gtttattgtt aggttttttt
      721 ccaccaatta ttttagcact gagcttgaat caaattatca ataaaaaaat aaaacagaaa
      781 atccagttga ttctatatgc gccgaatttt atctcagtag ttattattgt ggggatgctg
      841 tttttgttcc tatccgcaaa tggacctatt aatgggttag tagaaaaggt tacggggcaa
      901 ccaattatgt tcatgtctaa tccagcttat ttcagaacga tttatatttt atcgggaatt
      961 tggcaaggaa tcggctggtc atccattctt tacaccgcaa cgctggcggg agtcagtacc
     1021 gatttatatg aggcagcaaa tatcgatggg gcaaatattt tacaaaagat ttggcatatc
     1081 gatttgcctg cattgaggcc tgtgatggtg atcagcttca tcttggccgc cggcggtatt
     1141 atgaatgtag gatatgaaaa agcctacttg atgcaaactt caatgaacat ccctgcctca
     1201 gaaatcattt ccacttatgt atacaaagtc ggcttgcaat caggtgatta tgcctactct
     1261 gctgctgttg gtctgttcaa tatgattatt aatgtcgttt tattactgat tgtcaacaat
     1321 ataaccaagc ggctaaacga tggtcaaggc ttgtaatgaa aggagaaaat tatgaatagt
     1381 gctttatcaa aaatcgaccg tcaaatctta tggttgaatc gagtgattgt aactttttta
     1441 gtcgtcatca ccattgttcc gctgatttat gtactggtag cttcttttat ggacccagct
     1501 actttgatca ataaaggtat aagcttcaat ccgaaagatt ggacaataca gggatatcaa
     1561 cgggtatttg cagatgattc cattttacgc ggttttgtaa attcgttgtt ttactctttt
     1621 agcttcagct tattgactgt atttattacg atgatcactg cgtatccttt gtctcgacct
     1681 aacttggcgg ggaaaaagat tattatgact ttttttgtca ttacaatgtt cgtgggtggt
     1741 ggcttgatac ctacctattt attggtaaag aacttgggca tgttagatag tgtatgggcg
     1801 attatcgtac caggtgctat aaatgtgtgg aatattatct tagcccgtac ctattttagt
     1861 gctttgccaa aagaactttc tgaagctgct actatcgatg gcgccaatga cttgcaaata
     1921 ctgttcaaag tcatgcttcc attagcgaaa ccaattatgt tcgtattgtt tttatatgcc
     1981 tttgttgggc aatggaactc atactttgat gccatgattt acatcaaaga tcccgactta
     2041 cagccgttgc aactcgtatt aagaaatatt ttgatccaaa accaaccttc acaagacatg
     2101 gtgggagcca atactgccat ggcagaaatg aaacaaattg ctgagttgat caaatacgca
     2161 acgatcgtca tttctagtct gccattaatc ataatgtatc ctttcttcca aaaatatttt
     2221 gataaaggtg ttttagttgg ttctgttaaa gggtaagtat tgttcactat ttgtatgaat
     2281 aaaaattata aaggagattt taagatgaaa gcaaaatgga tgctgccaat cgtttttact
     2341 tccgtactaa ttttgggggc ttgtggaggc tcaaaagaaa agagtaaatc aagccctgat
     2401 tatgaactag aaaatgtctc ttttccattg aaagaaaaag tatctttaaa aatgatgtct
     2461 caaagtgccc ctttggctcc caatgatcct aatgacaaat tgattttcca acgattagaa
     2521 gaagagacca atctccatat tgattggaca aactacagta gtgattttgc cgaaaaaaga
     2581 aatttggata tcgctagtgg tgatttacca gatgccatct tcaacgccgc tgcaggtgac
     2641 tatgatttat taaactgggc ggaaagtggc gttattgtac cgattgaaga tttgatcgaa
     2701 gattatatgc caaatctgaa gaaaattttt gatgaaaacc ccgaataccg acaaatgtct
     2761 actgcacctg atggtcacat ttactctatg ccttggattg aagaattagg cgaaggaaaa
     2821 gagtcgattc atacagtaaa tgggatggct tggatcaaca aggagtggtt ggataatttg
     2881 ggtcttgaaa tgccgcaaac cactgatcag ttgatgactg tgttggaggc tttcaagacg
     2941 caagatccaa atggtaatgg tgaagcagat gaaattcctt ttagctttat taacaatgga
     3001 ggaaacgaag acttaaaatt tttaatgggg gcattcggtc taggtgataa tgatgaccac
     3061 ttagtcgttg ataacgatgg tcaggtacaa tttactgcta acaaagaagg gtataaagaa
     3121 gccatcaaat atttcaatga aatgaataat aaaggtctta ttgataaaga ggctttcgaa
     3181 caagattgga atacgtatgt tgccaaaggg aaagaacata agtatggcgt gtactttact
     3241 tgggataaag caaatatcac gggtgcagat gatagttatg acgtcttgcc agtcttagcg
     3301 ggaccagatg gaacgaaaca tgttactcgt acgaatggca tgggtttctc aagagatcgt
     3361 ttcgtaatta ctagtgcgaa taaaaacttg gaacttacag ctaggtggat agataaaatg
     3421 tatgaaccgt tacagtctgt ccaaaataac tggggaacct acggtgatga agcacaggcg
     3481 aatatttttg aattaaagga tggtatgtta aaacatttgc ctttagaggg gacagcaccg
     3541 ggggaactaa gacaaaaaac cgaagctgga ggaccattag cagttcttga ttcttattac
     3601 ggcacagtca ctactatgcc agatgatgcg aagtggcgtt tagatttgat gcatgacacg
     3661 tatttgccat atattacaga agacaatatc tatccacgtg tctttttaga aaaagaagaa
     3721 acagatcgat tagcaaaaat cgaaacggat atgtgggatt acatctatcg caaaagagca
     3781 gagtggatca ccggcggtaa aatcgatgaa gaatgggaag aataccttgc tgaattggaa
     3841 cgtgtaggtt tggaagaatg gattcaaata aaacaaactg gctatgataa ttttttgaag
     3901 ggagcacaat aagtgttagt agaagaaacg gcgattttgg ataaagcaaa tcgatttatt
     3961 gaaatgatgc gaggaaaagt taaccctcag tatcgacaaa actatcattt ttccgcaccc
     4021 atcgggtgga taaatgaccc caatgggttt atatattaca aagggcatta ccatctcttc
     4081 tatcaatact atccttacga tagtcgatgg gggcccatgc attgggggca tgcgcgcagt
     4141 agtgatttgg tccattggga agatctacca gtagcgttag ccccagatca accttatgac
     4201 agcggcgggt gtttctcagg aagtgcaatt gaaagagacg gaaaactata tttattttat
     4261 acaggctgtc aagaaattga tggtattagc catcagcatc aatgtttggc ggtctctgaa
     4321 gatggtattc attttagcaa atacagtggt aatcctgtgg tagcagaaaa acagctaggt
     4381 gaaaatgggc taatacaaga atttcgtgat cctaaagtaa ttgttcacaa cgatggttac
     4441 tatatggtag tagctactaa atctacacag tctactggta gaatagtgat gtttcaatcg
     4501 tcagatttgt atacttggca cttttactct gtgctgctag aagggacttc agagcaagga
     4561 ataatgtggg aatgtcctga tttattccat ttagacggac gagatgtctt aatcatgtct
     4621 ccgatacaaa tcaagaagaa cggactggaa tatcataata tcagttctac catggcttgt
     4681 attggtgagg taaactggga aacaggtcag atgatagttg ataatttcca tgaaatggat
     4741 tttggaatgg atttttatgc accacaaaca acaagagatc ctaatggtgg acgggtgatg
     4801 attgcttgga tgcagatgtg ggatcgtaca ttgcctacac atgagttagg ccatctttgg
     4861 gcaggctcta tgagtttgcc ccgagagtta agagtgaaaa aaaatcgatt ggtacaaaaa
     4921 cccatctcaa ctgtatatag tcatttagtt tatcaacaag gcagtgaaaa tattgcagtg
     4981 actgacacat cagtcgtatt tcgaaacgcg ctgtctgatt cttcatattt acatctagtc
     5041 gcagatttgg agaaagctga agtttttaca attgaattac tgcggtctaa gacggattgt
     5101 ctcaaactag cctatgacac tgctacacag gtttttgaat tggatcgtca gaaactagga
     5161 agagagctta caggggcgga agaagaccct ctgaatgtac gaaaagttga agtacctttg
     5221 attgataatc agctcgttct tgagattttt agagatacct catcaattga agtctttatt
     5281 aatgggttag aagttatgac ggctactttc tatgagctgg aaaaagctcg agatatcttg
     5341 tttcattcga tcggagaaag tcgtattcaa gcttttgaaa cagcgagtgt gaaataaatg
     5401 tttgattgct taggcgatga atcaattatt taataggttt tgaaggataa tgtttttaga
     5461 aaagaacaga tagctagatt tcccatggat ttgctattag tattttgaaa aaattagtaa
     5521 tttatgacaa aattcattat actaaacttg tgcagaaatg tgagggatca actatgaaag
     5581 caacaatgaa agatgtcgca aaattagcag gtgttggagt aggaactgtt tcccgggtat
     5641 tgaataacgg ttctgttaaa gcttctacta gagaaaaagt tgaagcagca atgacagagt
     5701 taaactatca accagatttt tatgcccggg ggttaaagat gaagcatacg aacacggttg
     5761 ctttgattct acccacggta tggcatccat tttttggcga atttgcctac catgtagaaa
     5821 cagcattaga aagacaaaac tacaagcttt atttgtgtaa ctccagtggt aatagtgaaa
     5881 aagaacaaga atatatccag atggtcagcc aaaataaagt agacggcatc attggaatta
     5941 cttattcaga tatcgatgaa tacatttcga gtaatctgcc ttttgttagt attgaccgtt
     6001 atttcactga agaggtgatt tatgtgaccg ctgacaatgc ggccggtgga cgtttggctg
     6061 caaatgaact ttatcgccga ggatgtcaga atgtagcata tatcggtggg taccaagaaa
     6121 caccgaatga aacgaagagt cgtcgaaaat attttgaaat cgagtgccgt caactgggga
     6181 tttcctataa agcgttagat atgttagaac ctttagacca tctctcagaa cgtgtaacaa
     6241 attttttgtt agagaatccc gatatcgatg ggatttttac gatcaacgat ccaatggcat
     6301 tagctgtcat tgatatgctt gaaaaaatag ggaaaaacgt accagaggat gtccaagtta
     6361 tcggatttga tggtcaaaag atgacagaag gagatcctta tctagtctca acgattgccc
     6421 aacctacaaa gcaaatggcg gaagtggcag tggcaaaatt aattgctgtc attaatggag
     6481 agacagtaga aaaacgtacc gtattgccga ttgaatttgg cgaaggtgac acaacgaaac
     6541 ctttagtgag aaacgatttt gcttagtgca aatacgtttc tttttttgaa aatgagtgaa
     6601 tgaaaggtgt agataaaatg ttatatggtg gaatagaagc cggtggaaca aagtttgtct
     6661 gtgggattgg taatgaacaa ttacaagtga tagaacggaa aagttttcct accacaacac
     6721 cagaagaaac gatggagcaa gtgtttgatt tctttgataa gtacaaagga aatatcgcat
     6781 caattggtgt aggagcattt gggcctattg atattcaaat cgaatcaaga acttacggat
     6841 atatcaccaa cacaccgaag ttagcttggc aaaattatca ttttgtagga gctttggaaa
     6901 acgccttgtc ggttcccatc tattggacta ccgatgtaaa tgctgcttgt tatggagaat
     6961 atatggcagg gtatggaaaa ggtaaaaata gtgttctgta ttacaccgtt ggtacaggtg
     7021 ttggtggtgg tgctgtagtg gatgggaaaa tagtcgcagg ttttagtcat cctgaaatgg
     7081 gacatatgct cttacaacgt cataatgaag atcaatttga aggaatctgt ccttttcatc
     7141 atgattgttt ggaagggtta gcatcaggac ctgcgattga aaaacgcttt ggaagaaaag
     7201 cccagactat ctcatttgat catccttatt ggacgattga ggcagattat cttgctcagt
     7261 gtgtgtataa cacaacgtta ctatatgcac cggaagtaat aattttaggc gggggtgtaa
     7321 tgaaacagcc gcaactactc gagttgattc gccaatcgtt taaagaaaaa atgggttcct
     7381 acgtggatac gcctactctc gaagaatatc tactaactcc aaggcttgct gacaatgcgg
     7441 gcttgattgg ctgcctagct ttagcaataa agaaactcaa tcattagaat agtatttatt
     7501 agaactattc ataacatacc ggaagtttaa aagggtattc tgaaacttaa atagtctcaa
     7561 ttcattcttc tttcttgaga atctgagtag agacttttat tctgtttcaa attaatataa
     7621 ttacgaaatg atattgagta caagaaagtt ctttttacca gatcttttaa atcgaaaaat
     7681 ctgatatata tatttatagt actaaaaatc tgattagata aaaagctaat tcaataggaa
     7741 aataaaggta gtgaataaaa gcaaagccct tgttagtagt taatctaaca agggctttgg
     7801 tagggaaaat ggtaggaaac catcttattt tttacgaaaa tcaggaactt tagtaattga
     7861 ataatgttga tttataggta ttcctcatcc atattatgtt ggctctttat tcccactcca
     7921 ctgttgcagg tggtttgctg gtaatatcat acacgatacg gttaacgtgt gcgacttcat
     7981 ttacgatacg gacactgatt ttttgcaaga cttcccaagg gatacgggca aagtcagcgg
     8041 tcatgccgtc aatagaagtg acagcacgga tacctacagt gtagtcatac gtacggccat
     8101 ctcccataac cccaacagag cgaatgcctg gtaggacggt gaagtattgc cagatgtcgc
     8161 gatctaaacc ggcattggcg atttcttcgc gcaagatagc gtctgattca cggacgattt
     8221 ctaatttttc ttctgtcaat tcaccaagga cacgaatacc taagcctggt ccagggaatg
     8281 gttggcgcca aacgatgctg tcaggcatgc ctaattgggt acctaattca cgtacttcgt
     8341 ctttgaacaa tgtgttcaat ggctcgatca gcttgaattg catgtcttca ggtaatccac
     8401 ctacattgtg atgtgatttg atggtttggg cagtttcagt tcctgattcg atcacatcgg
     8461 tataaagggt tccttgtgca aggaaagaaa cgccttcttc accggcaagt ttggttgctt
     8521 catcatcgaa gacatataca aattcatttc caatgatttt acgtttttct tctggatcag
     8581 acacgccagc aagttttgat aagaaacgtt ctttggcatc gacttttata atgttcaagc
     8641 caaattttcc gccaagactt tccataactt gttctgcttc acctttacgc aacaatacgt
     8701 gatcaacgaa gatacatgtt aattgatcgc cgatcgcttt ttgtaaaaga acaccaacaa
     8761 cagaggaatc tactccgcct gaaaggccta ataaaacttt tttgtcaccg acttgttcac
     8821 gaatttttgc gatctccatg tcgatgaagt tatccattgt ccagtcacca gtacattggc
     8881 agacatctag tgtaaaatgg cgcaacaagt catttccata ttcggaatgg cgaacttctg
     8941 catggaattg gattccgtac attttgcgtt ctgcattttg gatcgatgcg atggggcaat
     9001 ctttgctggt agcaacgaca tcgaaatcag tcggtgcttg ggtaactagg tcaccatgac
     9061 tcatccaaac ggtttgtttt tcaggagtgt tttggaaaag ggccgcttct gcagaagtga
     9121 tttccaattc tgcttttccg tattcacggt ttttggctgg tttaactttt ccgcctaatt
     9181 tataagtaat caactgcata ccgtaacaga ttcctaaaac tgggatcccc aaatcaaaaa
     9241 tcttttcatc aataccaaag gccttctcat cataaacact gtttggtccg ccagaaagga
     9301 tgattccttt agggttcatt gcctttactt cttctgcggt aatgcggtgg ctcatcaact
     9361 ctgagaaaac accgaactca cgaatacggc gagtgatcag ttggttatac tgactaccgt
     9421 aatcaagtac gataattttt ggctcttcgt caaatcgtgt tggtgaagac aaatttgaat
     9481 aaaacttagt ccgatatgcg gcgcgttctg tgcgccgcat atttttttag ttttcaaaga
     9541 tcagaccttg ttgtaaatag atccgtgccc gaaagttata aaagttgcga taaccaaacg
     9601 caattcgttt aatcagcttg atcttgttat tcagcccctc agtgacgccg tttgagtggg
     9661 acaccttaaa ggcatttgaa atacccgatt ggtagcgatg gaagatcgtg aatttctttt
     9721 taaacgactg aggtaacgta gatgaaattg ttttaagggt ttcttgaaag ccttccgta
//
LOCUS       DAZAOD010000097         9488 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000097 DAZAOD010000000
VERSION     DAZAOD010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.099"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            124..771
                     /locus_tag="ACHDPO_002383"
     CDS             124..771
                     /locus_tag="ACHDPO_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFN3369971.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    900..1116
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1164..3809
                     /locus_tag="ACHDPO_002384"
     CDS             1164..3809
                     /locus_tag="ACHDPO_002384"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFN3369972.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4119..5432
                     /locus_tag="ACHDPO_002385"
     CDS             4119..5432
                     /locus_tag="ACHDPO_002385"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFN3369973.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5422..6075
                     /locus_tag="ACHDPO_002386"
     CDS             5422..6075
                     /locus_tag="ACHDPO_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFN3369974.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6130..6822
                     /gene="radC"
                     /locus_tag="ACHDPO_002387"
     CDS             6130..6822
                     /gene="radC"
                     /locus_tag="ACHDPO_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFN3369975.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6972..7172
                     /locus_tag="ACHDPO_002388"
     CDS             6972..7172
                     /locus_tag="ACHDPO_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFN3369976.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7426..9105)
                     /locus_tag="ACHDPO_002389"
     CDS             complement(7426..9105)
                     /locus_tag="ACHDPO_002389"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFN3369977.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9107..9319)
                     /locus_tag="ACHDPO_002390"
     CDS             complement(9107..9319)
                     /locus_tag="ACHDPO_002390"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFN3369978.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
BASE COUNT         3008 a         1694 c         2033 g         2753 t
ORIGIN      
        1 gatgcaagct tttgaacacc gttttatttg tctcacaccc ttttccttcc tacttgtaac
       61 cttgctcccg tgttagaaac atgttacact aaatatgtga aattattaac aaggagcgtc
      121 gttatgcgag aaaaaacaga tacactgcca aaagcaactg cgaaaagatt acctttatat
      181 ttacgctact tgaagttgct ggatgactca ggtataagta gaatcaaatc aaatgagttc
      241 agcgaaatca cccaaattcc ttctgcaacg atccgcagag acttctcgca attaggcgag
      301 ctaggcagaa gcggatatgg ctatgatgtc ccttttctta tcgatgtatt caataatatc
      361 cttaatacta aagaagaaaa acgaatcgca ttagtaggat atggaaatct tggcaaagca
      421 ttgaaacaca acaattttag aagaaatgaa aatctaaata tcgtgtgcgt ctttgataat
      481 gatccagcac tgatcaatcg agtaattgat ggagaaatga tctatccgat tgatcgtttc
      541 gcggagatag ccaaagcaaa aaatgtgaca gtagcaatct ctacggtacc aagtaaatat
      601 tcacaatctg ctattgatga aattgtcaaa ggaaatgtaa ccgctatact taattttgcg
      661 cctgacagag taactgtccc agcttatgtc aatgttcaat acattgattt gacaaccgag
      721 ttgcagacgc ttatttactt tgatgagaat tactcagaag ttttttctta ggaaaatttg
      781 agtaggctta ttgatcttgc gagaactcgt cgtaattctt tcaaaaattt tttagtacta
      841 aatgaagtgg ttttttcacg accacttgtt gactaaaaaa aaaaaccatt gtagaatgaa
      901 gcataacgct gaacaagagg agtaactggc acattcattc ttagagagag aactatctgc
      961 tgaaaggttc tcaatgacaa ccagtgaagg tagcttggga gtttctgtct tgaatggagt
     1021 agagatagac gagtcgtgat cgttaactca cttgagaggc aataatgatt gattattgca
     1081 atttaggtgg taccgcgtaa atcatacgtc ctagaatacg aaagtatttt aggacgtttt
     1141 ttagtttaaa ggaggaaaac agcatgacgg aagaaaataa cctatcaaca aaatataatc
     1201 cgcaagaagt tgaagctgga cgttatcagc attggttaga acaagatttg tttaaaccga
     1261 gcggagataa aaaagcaaaa ccttattcaa tcgtaatccc gcccccaaat gttactggaa
     1321 aacttcattt agggcatgct tgggatacga ccttgcaaga tatgctgatt cgtcaaaaga
     1381 gaatgcaagg atatgatact ttatggctgc ctggtatgga ccatgcagga atcgcgacac
     1441 aagcaaaagt agaagcgaag cttagagagc aagggatttc tcgttatgat ctaggtcgtg
     1501 aaaagttcat cgatcaagtg tgggaatgga aagaagagta tgcgagccac atccgcgaac
     1561 agtgggctaa aatgggctta tctttagatt acagtaggga acgttttaca ttagatgatg
     1621 gattatctga agcagtacgt aaagtttttg ttaccttata cgaaaaaggt ttgatttatc
     1681 gtggtgaata tatcatcaac tgggatcctc aagcacgaac agctctatct gatatcgaag
     1741 ttattcataa agatatcgaa ggcgcctttt atcatatgag ctatgaacta gcagatggat
     1801 caggcgtagt agaaattgcg acaacccgtc cagaaacgat gttgggagat acggcgattg
     1861 ctgttcatcc agaagacgag cgttatcaag cgctcatcgg caaaaaagtg attctacctt
     1921 tagtcaataa acaaatccca atcattgcag atgaatatgt agatatggaa ttcgggacag
     1981 gtgtagtaaa aatcactcca gcacatgatc caaacgactt tgaggtaggt aatcgtcatg
     2041 atcttccacg cgtaaatgtt atggatgatg atggtacgat gaatgaacta gcaggaaaat
     2101 atgctggaat ggaacgtttt gctgctcgta aagcaatcgt gcaagatctg aaagaaatcg
     2161 gtcgattgat taaaatcgat acgatgatcc acagtgtggg tcattccgag cggacaggtg
     2221 tcgttgttga acctcggctg tctactcaat ggtttgtaaa aatggcgccg ttagcgaaaa
     2281 aagccattga taaccaagaa acagatcaag cagtggaatt cttccctcca agattcaatc
     2341 aaacgttttt acgttggatg gaaaatgtcc atgattgggt aatctcacga caattatggt
     2401 ggggacatca aattcctgca tggtatcaca aagaaacagg tgaaatgtat gtagggatgg
     2461 aagcaccagc ggatagtgaa aactgggtac aagatcctga tgttttagac acttggttta
     2521 gttcagcttt gtggcctttc tcaacaatgg gctggccaga tacggaaagc gaagattata
     2581 agcgatactt ccctactagc actttagtaa ccggttatga catcattttc ttctgggtaa
     2641 gcagaatgat tttccaaagc ttggaattta ctggcgaacg tccatttgag aatgtcttga
     2701 ttcatggatt gattcgtgac gaacaagggc ggaagatgag taaatcatta ggtaatggaa
     2761 tcgatccgat ggaagtaatc gaaaagtatg gagcagatgc tctccgctgg ttcttatcga
     2821 atggttctgc accaggacaa gatgtccgct tcagctatga aaaaatggat gcttcttgga
     2881 actttatcaa caaaatctgg aatgcttcac gtttcgttat catgaatatc gaaggaatga
     2941 ccgtagaaga gatcgattta tctggagaaa aatcagtggc tgaccggtgg atccttactc
     3001 gtttgaatga aacgatcgaa cgagtaactg agctatttga tcgttttgaa tttggtgaag
     3061 caggtcgaca actgtataac tttatctggg atgatttttg tgactggtac atcgaaatga
     3121 gtaaagaagt actttatgga gatgatgctg tttcaaaaca aaccacccgt agcatcttag
     3181 tccatacact tgatcagatc ctacgtttat tgcatccaat catgccattc gttacagaag
     3241 aaatatggga acatattcct catcagggaa attctctagt agtggcagaa tatcctgttg
     3301 tacgtccaga gtttgatgat gaaacagctt ctaaagggat ggaagtattg aaagaattga
     3361 ttcgagccgt tcgaaatatt cgttcagaag tgaatacacc attgtctaaa ccaattacgt
     3421 tgctaattaa aacaaacgat gctaaaatcg atcaattttt agttgaaaat acaagctata
     3481 tcgaacgctt ctgtaatccc gaagagttga cgatatcaag tgagatcact gcgccagatc
     3541 tagcgatgtc agctgttctg acaggtgcag aaatcttctt gccgttagca ggattgatca
     3601 atattgaaga agaaatcaaa cgattagaaa aagaactgga aaagtggaca agcgaagtaa
     3661 aacgtgtcca aggaaaactt tctaatgaac gttttgtttc taacgcgccg gaagaagtag
     3721 tagaggcaga gcgtgcaaaa gaaaaagatt atttagagaa gcaaacggct gtcaaagaac
     3781 gaatcgaaag tttgcgtact attcaataag aatagaaaaa gagagtgtga aatcagctag
     3841 ctattactaa aagctagctg attgaacatc gttacaggaa agagtttgag cctcactctt
     3901 agcttcgatt cataaggaga tgtgacataa attttgtcgc atctcttttt tagtctactc
     3961 ttattatgta ggagaaggag ggaggtggat catgtatcaa gagtcaataa agtagttgat
     4021 aaaatcgttc ctctctctgt ttcttttctc tttgtcatac ttttattttt cttatgtgtt
     4081 ctatttgtta taataaaaga gaaatggggg aattgttgat gacgattgaa gaagcaatag
     4141 aatggatcca tagtcgatta ccatttggtt cacgtcctgg ccttgaccga gtcgaagctt
     4201 tattagaagt ggtagggcat ccagagagaa aagtaaaaac gatccatatc gctggaacaa
     4261 acggaaaagg ttctactgta gcttatttga gaagcctatt agaagaggct gggctgacag
     4321 taggtacatt tacttcacct tatatcgaaa cgttcaatga acggatcgca atcaatggca
     4381 aaagcattcc agacaatgat ttgatccagc ttgtaaaaaa atatcagcca ctgatcaaac
     4441 aacttgatca atttgaagca gtagctggta ttactgaatt cgagacatta acagcaatgg
     4501 catttgatta ttttttgatg aagaaagtgg acgtagcgat tatcgaagtt ggcttaggcg
     4561 gcttattgga ttctaccaat gtagctgtac caatgctgac gggaataaca acgattggac
     4621 ttgatcatac cgaaatactt ggagatacaa ttgaagaaat cgctgcacaa aaagctggaa
     4681 tcatcaaaca aggcgttcca gtagtaacag gaaatattgc cccagaagct tttactgtca
     4741 tccaacaaac agctaaagca aaaaatgcac cgctttatgt atacggggaa aattataaaa
     4801 taaactatct gcatcctgat gagatgtggg gagaagtatt tgaatttttt aatgaaatag
     4861 gaaagatccc tcaattaacc actccgcttt tagggcaaca tcaagctgaa aatgcaggag
     4921 tagccatcga attgtatttt gtttactgtc aattggaaaa gctgcctttc cgagaaaaag
     4981 atgttttgaa gggattgaag aaatctcgat ggccaggaag aatggagcgt ttgagtaacg
     5041 agccattagt tgttttagat ggtgcccata atacgcatgc aatgaaccgg cttgttgaga
     5101 atttgaaaaa agaattcaaa ggatatcaaa tcaacatttt gttttccgcc ttacgaacta
     5161 aaaatgttag agaaatgcta gaacgattgc agcaagtacc aaatgtccat atttatttga
     5221 cgacctttga acatccaaaa gccatcgaat taagtgaagt atcagattta gcaagtgaga
     5281 gagtatcaat cgtttcattg tggcaattcg gattagcaga tatattggaa aagatgacaa
     5341 atgaagacgt attagttgtg accggttcac tttatttcat ttcagaagtt cgccatttat
     5401 taatacaatt aggaggagat catgaagtat aatgcagtga tttttgacat ggatggtttg
     5461 ctgttcgaca cagagttagt gtattacgaa gccacacaag tagtagcaga caagatgggt
     5521 tttccttatg ataaagacct gtatttaaaa ttcttaggtg tttcagatga agaagtatgg
     5581 gcgaattatc atatgatttt ctcggaattt ggcaaaacaa gtgtacaaag attcatagat
     5641 gattcatacc aggaaacgct tgaacgtttt tcgcaaggag cggtacaaat gaagcccggt
     5701 gtgttggaac tcctctcttt tttagaagaa catcagattc ccaaagttgt cgcttccagt
     5761 aaccaacgag cagtcattga acttttattg aagaagaaca atctgtttga acgatttgag
     5821 acgattgttt ctgcagaaaa tgttcaacga gcaaaaccag acccagaaat tttcttgtta
     5881 gctaatcaga agctaggtac agcgaagaaa gaaacattga ttttagaaga ttcacaaaat
     5941 ggtattttag cagcttctgc ggctgagatc ccggtagtca tggtaccaga tctgcttcca
     6001 ccatcccaag aattgatcaa aaaaacagct ggggttgttt cttctttaca tgaaatccct
     6061 gcattgttaa aataaaaatc catctctttt cgtatcttat tttagataag atagaaagga
     6121 gatgtttttt tgggaaaacg attgatcaaa gaagtaccta ctagctcttt accaagggaa
     6181 cgtatggaaa tttatggcgc ggaagcttta tcggatcagg agcttttggc aatcttactg
     6241 cgtaccggtc aacaccctta tagtgtgatg tcgattgctg gaaatctgtt aaaaacgttt
     6301 ggaggactgg cctctttacg acaggctact ttgcatgagt tagaagagat tcgagggata
     6361 ggacgcgtga aagcaatcga aatcaaagcc ttgatcgaat taggtcgacg aattcagacg
     6421 gatcatgaaa gagcggctcc accggttcgt accagctacg aattggccca gcaattgatt
     6481 ctggaaatga aagatcacaa acaagaacat ttggtttgta tttatttgga cacgaagaat
     6541 caagtgatct taaaaaaaac agtgttcatc ggttcgctga atcagtcagt cgctcatcct
     6601 agagaaattt tccattatgc tgtacgttat tgtgcagcaa ggatcgtttt agcgcataat
     6661 catccttctg gtaatgttat tccatcgcag caggatatga attttaccaa aaggatacaa
     6721 aagtgtggag aaatgatggg gatcactgta ctggaccact tgatcatcgg acgcaaacga
     6781 tattttagtt tgagagaaga aggaatgatg gaagagaagt aagttgcttt cttgcaaaaa
     6841 aaatgaagca agtgtacaat tatattgtaa ttttgtttgg gaatagaagt tgaaacatct
     6901 gttgcacctc tatcgtacac gagcaatgtt acaatttaaa ttagtgcttt tggcacgagg
     6961 aggatattat tatggaaaac ggaacagtaa aatggttcaa cgctgaaaaa ggatttggat
     7021 ttatctcacg tgaagatgga agcgacgtat tcgttcactt ctcagctatc caaggtgacg
     7081 gattcaaaac attagaagaa ggtcaagcag tgactttcga cgttgaagaa tcagaccgcg
     7141 gcccacaagc tgcaaacgtt gtaaaagctt aattttatct gtaaatcaaa ttgatggtag
     7201 acatcaattt ttacgagaga acaaagcgag taacaaaaat acctgccaca agagacaatt
     7261 tctcttgtgg caggtatttt tttgtatgaa aaagtaaata aatttaagag gctatgaaag
     7321 agccaccttg tatcaaggaa taagaacaaa caaaaatggc ttctcatgtt tttcatttgt
     7381 tttctcttat attcaggaca aggtgctgat ttcataacct cttatttatt cttcatctgg
     7441 tgtcattacc attggcaaaa tcattggatg tctttctgta cgttcgaata agaaaggctg
     7501 aagcgcgcca gtcatcgctt ctttcaattt atattctgaa cagtcaggtc cattcaaaca
     7561 ttctcttaaa gcgtggaata agattcgctg agcttcattg atcatttctc ctgattctcg
     7621 catgtagaca aatccacgag agagaatatc tggaccagcc aagatttctt ttttcttgat
     7681 atccactgtc gcgacagcta atacaagacc ttcttctgaa agcaggtgac ggtcacgtaa
     7741 aacgacatta ccaatatcac cgatcccgct accatcgata tacacatctc cagccacaaa
     7801 atgcccagca ggacgcgcag aatcgctagt taacgctaaa acatcgccat tttccatgat
     7861 gaagcagttt tctgcaggaa cacctacatc ttgtgctaga gaagcatgta ctttcaacat
     7921 gcggaattct ccgtggacag gaataaaata ttttggcttc atcaaacgaa gcattaattt
     7981 ttgttcttct tgtccaccgt gaccggaagt atggatgtta ttgatttttc cgtgaatcac
     8041 ttctgcacca gcttcagaca gcaaattgat caaatgattg acacttgttg tattaccagg
     8101 aataggtgaa cttgaaaaga tcactgtatc gtctggctgg atttggattt gacggtgagt
     8161 accattcgcg atgcggctca acgcggccat cgcttctcct tgagaacctg tacataggat
     8221 catcgtttca ttggcaggca agcgattgat ttcgtgtgca tctacaaatg tgccgtctgg
     8281 aactttgata tatcctaaac gttgaccgtt gacgatggca ttttccatgc ttcgtccgaa
     8341 aacagcgatt ttacgaccag ttgccacagc ggcatctgct gcttgctgca aacggaagat
     8401 gttagaagca aagctggcaa aaatgatacg tccttcgatt tttgaaaaga tcttcaaaat
     8461 agaatgccca atcgtttttt ctgatttagt aaatgttgga atctcagcat ttgtactatc
     8521 agataaaagg cacaagactc cttcttcccc gatacgagcc attttatgca agtttgctgg
     8581 ttcgccaaca ggagtgaaat cgaatttgaa gtctccagtc gctacgatat ttccagaagg
     8641 tgttttcacc acgatcccta atgcatctgg gatactatgg gtcgttctga aaaagctgac
     8701 agaagtcttt ctaaaacgga tgatcgtatc ttcattgatc tcatggagct ctgcatctcg
     8761 aagcaagcca tgctcatcta atttgtttgt gatcaacgct aatgcgagag gaccagcata
     8821 gataggaata tttgcttgtt tcagcaagta gggtattccg ccgatgtggt cttcgtgccc
     8881 gtgagtaatc accaaggctt ttactttgtg taagttttgt atgatgtagc tgtagtcggg
     8941 aatgacatag tcaattccaa gtaaatcgtc ttccgggaat ttgatcccgg catcaatcaa
     9001 aatgatttca tcttggaatt gtaccccata cgtatttttc ccgatttcac ctaatccacc
     9061 aatagcaaag acgcctgtct cgttattttt gatggaaagt ttcatattaa aactccacta
     9121 atgagaaatc agcattttct ttttcgtact ctagatgact tccttctaga agttgaacga
     9181 attcaatatt gtatggggta ttttcttcca cacgttggcg agcgtctaca tcgctttttg
     9241 cctcaatgta aagagatttt gtttcttccc gtttagggtt gcgtactttt gtttcttgat
     9301 aataaacttt atagatcatt gttttgtctc ctttatctgc gtaaagcagt gatttagcta
     9361 gttgattttt ttagacaaca caaaacgagg ggacaagcca cctggttttt catatgcttt
     9421 gactagaata ctggattcga gtcaaagaga caagcctcgt ttttgcttat ctgttcggat
     9481 attttttc
//
LOCUS       DAZAOD010000098         9341 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000098 DAZAOD010000000
VERSION     DAZAOD010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.100"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(119..1168)
                     /gene="recA"
                     /locus_tag="ACHDPO_002391"
     CDS             complement(119..1168)
                     /gene="recA"
                     /locus_tag="ACHDPO_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFN3369979.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(1277..2518)
                     /locus_tag="ACHDPO_002392"
     CDS             complement(1277..2518)
                     /locus_tag="ACHDPO_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFN3369980.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(2758..3336)
                     /gene="pgsA"
                     /locus_tag="ACHDPO_002393"
     CDS             complement(2758..3336)
                     /gene="pgsA"
                     /locus_tag="ACHDPO_002393"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFN3369981.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(3545..4468)
                     /locus_tag="ACHDPO_002394"
     CDS             complement(3545..4468)
                     /locus_tag="ACHDPO_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFN3369982.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(5207..6493)
                     /locus_tag="ACHDPO_002395"
     CDS             complement(5207..6493)
                     /locus_tag="ACHDPO_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFN3369983.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(6486..7754)
                     /locus_tag="ACHDPO_002396"
     CDS             complement(6486..7754)
                     /locus_tag="ACHDPO_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFN3369984.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            8006..8467
                     /gene="mscL"
                     /locus_tag="ACHDPO_002397"
     CDS             8006..8467
                     /gene="mscL"
                     /locus_tag="ACHDPO_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFN3369985.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(8526..8972)
                     /locus_tag="ACHDPO_002398"
     CDS             complement(8526..8972)
                     /locus_tag="ACHDPO_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3369986.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(9065..9310)
                     /locus_tag="ACHDPO_002399"
     CDS             complement(9065..9310)
                     /locus_tag="ACHDPO_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFN3369987.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
BASE COUNT         2577 a         2028 c         1658 g         3078 t
ORIGIN      
        1 tattttatgt acccactcgt ataattaaat aactcacgat ttctttattc aataaaaaaa
       61 cggcaggtca aggagagtac ctactcttca gaccagccgt ttttgtttat cataattttt
      121 attcttctac taaaggcaat tcttcttgtc ctttttcatc ttctgggaca gcgacttctt
      181 caccaatacc ataagctgct ctaactagag cagaaacttc tgccatcatt tcaggatgat
      241 tagccatata gattttagcg ttttcccgtc cttgaccaat ccgatcttct ttataagaat
      301 accaagcacc gcttttatca acaatgtctt tttctactgc catgtctaga agttctcctt
      361 cttgtgagat ccctaaacca tacatgacat ctacttcagc gattttgaaa ggaggtgcta
      421 ctttgttttt tacgactttg atctttgtac ggttaccaac aatatctgta ccttgtttca
      481 attgttctgc acgacgtact tccaaacgga tcgttgcgta gaatttcaat gcgcgtcctc
      541 caggagtgat ttctggattc ccaaacatca cgcctacttt ttcacggatt tggttgatga
      601 aaatagcgat tgtttttgtt ttgttgatcg aaccagagag tttacgcaat gcttgagaca
      661 tcaaacgtgc ttgtaacccg acatgtgagt cacccatttc gccgtcgatt tctgctcgtg
      721 gaactaaagc agcaactgaa tcgactacta cgatatctac agccccactt gatactaaag
      781 catcagcgat ctctagacct tgttctcctg tgtcaggctg tgaaagaagt agttcatcga
      841 tattcacacc taatttttgt gcatattgcg gatctaacgc atgctcagca tcaatgaaag
      901 cggccgttcc gccatttttt tgtacttctg caatagcgtg tagtgcaact gttgttttac
      961 ctgaactttc aggtccatat acttcgatga tacgtccacg ggggtaaccg ccgacaccta
     1021 aagcgacatc taacgcaaga gagccacttg gaattgtaga gatttgttgg tcgatttttt
     1081 cgcccaattt cataatagag cctttaccat agctcttttc aatttttttc agtgcagcat
     1141 ctaaggctgc tttacgatca tctgccaata cgataatcct ccttatattt acaaatcaga
     1201 gcaacatttc attatcctta tcatatcttt tttagtgaaa aaaagcaaga aaaaaccgaa
     1261 caaatattcg catttatcat tttcttaaaa gctgttttct caaaagatca aatccttgca
     1321 taaccgcatt atatctgata gcagcacgat ctctggcaaa gtgatatttt tccgaaacca
     1381 cgccgtcttt agatgaaata gcgatccata ctgttcctgc agattgacct tctaacgtgt
     1441 ccggtccagc cactccggtg aaagctacac tgtaatctgt tcttgctatc tcacgtgctt
     1501 gaatggccat ctgctccaca cattctttgc tgactgttcc atattctgct aatagctccg
     1561 gatcaatctc cagaaaacca gcttttgttt ggagcgagta ggtaacgaat ccgcctggaa
     1621 atacttcaga tacaccagca atgtcgccta atgcggcttg gaaggcgccg gctgtcaaac
     1681 tttccgctgc tgttacagtc tgcttgtttt ctttcagtag ttccactacg acttttgcta
     1741 gcgaattatc atcgccgtat ccataaaaat attcccctac tcgttcttgg attttttctt
     1801 ctaatgctaa aagagcttga ttccctgcct gaacatcatt tgttttcact gtcagtcgta
     1861 atgtcacttc atttggtttg gcatatggtg cgatcgttgg attgatctgt gtctcaatca
     1921 gatcttttag ctcagtgacc agtcgcgatt caccaatccc ataaaagcgc aaaactttag
     1981 aaattagttt ttcttcagaa ggaaaacgtt cctctagtaa aggacgtact tgttccacaa
     2041 acattggttt caactcatta ggcggaccgg gaagaaggat atacgcatgt gtatctgttt
     2101 gataaaaagt ccctaaagca agccctgtac gatttggtag aggaaccccg ccttcgataa
     2161 tctgggactg ttgcagattg tttttggtca tttttcgatg ggttgtttca aaatatgcca
     2221 ataatttttt gtatccttcc gtattttgta tgagagactt accgaggtga gccgcagttg
     2281 cttcttttgt caggtcatct tctgtcggtc ctaatccgcc acataagagt atgagttcac
     2341 ttcttgtttc agctagagca atcaactctt ctaaacgctg ctgattatct cctacaactg
     2401 tttgataata aacttcgata cctagatcag ctagctgttc tgacaagaaa gtggcattcg
     2461 tattcacgac ttgtcctagt aaaagttctg ttccgacagc tattatttct gctttcatta
     2521 cttcccgctc ccttatatag tatacgctgt atttttatat ttttttattt aaaaagaggg
     2581 caaggagctg tgacaaaaat cttgtcacag ctccttgttc caaataaaca gtgttctcct
     2641 gccaaaacct cggtcataag tcacaatata cataaaacat gaaaagctgt tttttgaaat
     2701 tatcccttgt gactcagagt tagacggcag gctcacaacc tctccactaa acgatactta
     2761 cattgatcct ttgaacacac cgctgttttt gatgaagtaa tccacacctg aatagatagt
     2821 aaagatcaga caagcataaa gcatgatttg atctactgga ataccgatca ggctgaatgg
     2881 gatattattg ataaacagca agataatagc aaccatttgt gtagccgtct tgacttttcc
     2941 cggccaagct gcagccatga cttctccatg ttcgacaagt agtaaacgca agcctgtgac
     3001 ggctaattca cgacagacaa tgatcgctac tacccaacca ggggcctttc cttggtcaac
     3061 caacatgata aaagcagtca taactagcat tttatctgcc aacgggtccg caaacttgcc
     3121 aaaattagtg acaaggcctc gcgcacgggc aatttttcca tctaaccagt ctgtgatact
     3181 agctaaagca aaaataactg cacctactag ctgtgtgaca gccagtgtgg tgtctcctac
     3241 gttaaattgt ccccaatcta aaggtaaacc tacaaccaaa atgaaaatcg ggatcataca
     3301 aattctaagt acagttaatt tatttggtaa attcacacta tcgactcctt tcttccctat
     3361 tctacgtgac tatcagcgaa gtttccaccg atattattta cttttccaaa tgaatttatt
     3421 caaaggagta tttttattga aattgatctt tttgaattaa cgaagaagga ccgcgacaca
     3481 gatttgtcac gatccttctt ttttatacct acaagtaaac agatgcgtaa actaatttat
     3541 acgatcattc tgcgtattga agagtaaggt tcacattttt tggactctga ttgttttccc
     3601 ctggattaac tggtacggat tctccattcg ctttgatcgt tgcattgctt gctgcaccaa
     3661 tcgtgatggt cgcatttgtt gctgtttccg gtaacacggt actctgtgtt tcatttgctg
     3721 ccagtgtccc ttgataaaca taggcattgt ctactagcac acctaaccat acacgattga
     3781 cagcagtaaa ttcaagggtt acaggcttgg tagcgtctgt gatatttact gcgatggcac
     3841 tgccagaatc ttctcctgta gctattgcca ttttcttttc ttcacttgat tttgttgttg
     3901 attctactgt agaagactct ttggtctgcg tgctttgctc tgaggaagag gactcctcga
     3961 ctgatccttc tactttaagc gaagaagctg tgtctccgat tattggatca gcttgacgat
     4021 cttgccaagt catatagccc acgacaacga caatcgccaa agcaaccaat cctaataaaa
     4081 tgacaggaag acttgtccaa aagcgacttg gatgcgattc ttcctgatgc attgcttttc
     4141 tagaagtact tactgtttca ggctgcggac gttcagggac cgatcctgtc aatttgcttt
     4201 tcccatcaaa aacatcgact aaatggtctc catcttctcc tacagcttca gcgtattgcc
     4261 gaataaatgc ccgcacgtaa aatttaccag gcaattggtc aaaatcatca ttgtcgattg
     4321 cttccaaata acgtttttga atttttgtaa tctgctgtaa ttcatctaaa gatatttttt
     4381 tattcaggcg tgcttgccgt aatttttctc cgatggtttc aaaagccact cgttcatctt
     4441 ctccagtctg tttgattctc cgaagcatct gctgttgcaa cgaaagacgt tatgtttggg
     4501 tgctgtgaca aaagtcatgt cacagctcct tttttccgaa taaacattgt tctcctgcca
     4561 actcctcggt cacaagtcac aatatccaat aaatataaga agctgttttt tgaacttgtt
     4621 ccttgtgact cggagttaaa cggcaggctc acgacctctt tcttaaacgg tgttcaatca
     4681 gctgttcctc ggtattagct caaaaaccgg caaaatataa ggagatattt ttccgtatgt
     4741 ttctctaata ctcaggtcaa aacgctgatt tcacaacctc ttccttaaac ggtgttcaaa
     4801 agcttgcatc tgcggtaata agtccaacca agttaaaaac attaagaagc tgtttttact
     4861 tggctgttct tattacttga tgcagggcag ctttttcaca acctcttggt acacggtgtt
     4921 ccagaagtag cttcttcggc aataagccga aatatcacaa aaatttgaga agcaattttc
     4981 gtaaattcct tcttatttct tgaagctgac cacttctgtc acaacctctt tgattacttc
     5041 gtttgatttt attttaatat aagttgatta aaagagagca tgatttgttt tattttctca
     5101 ctaatttttc caacacaact aagaatacca taaaagctga ttttggagga ggttcctact
     5161 acaagtctaa aacgaaattt aagacttttc ctcataaaat actggtttat tttggtctca
     5221 tgtaaaactc gctgaaggcc tcttcactta taaatgcttc cccagctgcc agtacgtctt
     5281 tcatttggat cgaatcgatg atttcaggaa gatcaaataa agttcgatcg ccaaataaac
     5341 tttgcgtaaa ttgattggca atatattcga tcgaatttaa tgattggaaa tattgtccaa
     5401 gcattttctt cttcagcaaa tcgagatttg tttctgacac ttccggatca tcagcgaatc
     5461 caagaatgat ttctttgact ttttctgctg ctttctctgg ttcgtccgta tctccgctga
     5521 agtccgcaaa gtgaaattca cgatccaagc tgaattcaaa accaaagctg tcatcgataa
     5581 ttccttgatt gtacatcgct agatagtttc gagaagtatt gcctaaaatc atttggaaca
     5641 acagattgat tgctgtttta tagcgtaaca gttctgttcc ttcttgcggc aatgtgtcta
     5701 atcctttaat accaagtaca aatttatctc gtgtaatggc tgcttccaat gcactttgtt
     5761 tgatgatttc ttttgtgttt tcagggaaat aacgtacaat ttcttgcttt ggagggaaat
     5821 tttttgcttc ttggttttcc cgaataagtt tcatcaattt ctcaggctcc atcttaccaa
     5881 ctacaaataa aaccatattg cttggctgat aaaacgtccg atagcacgta tacaagtctt
     5941 gagctgtgat tttgtcgata ctttcaaccg tgcccgcaat atcgatatgc aatgggtgtg
     6001 taggatacaa gttatttagt atgccaaaaa acatccgcca gttagggtcg tcttcataca
     6061 tttggatttc ctgaccgatg attccttttt ccttgtttac agtttcttct gtgaagtaag
     6121 gtgcttgtac aaaatcgatc agagtcgtca gattcttttc tacctgatcc gtcgtagaaa
     6181 acagatagct ggttttcgta aaacttgtga aagcattggc ggaagctcct tgtttcccaa
     6241 ataattgaaa gacatcacca tcttcttttt caaacaactt atgttctaaa aaatgggcaa
     6301 ttccatctgg aactttcacc ttttcttttt caccataggg aataaattcg ttatcgatcg
     6361 aaccataatt cgtactgaac aaaccatatg tcttgtgata gtcattttta ggcaacaaat
     6421 acacggtcaa accgtttggc agtacttcat gataaagtgt ttcattgatt tgctcatatt
     6481 ctgttttatt catttgcatt tcctcctgct aaaaagaaga ttgcctgcaa ttcgatttgc
     6541 tcagctactt gttgtatctc tttgatcgtt acgctctcca tacgtttcaa ccattcttca
     6601 tcagataatt ttgtttccgg cagccagctg tccaaaaaag aagcttcgat tgccgcttgc
     6661 ggagagtcta gagaaagcag atattggttt ctcagcattg cttttgtctg agacagttcc
     6721 aactctgtta tttcaccatt tcgcaaactt tctaattgct cgtgaatcag atgaagtact
     6781 tgatttcggt tcttttcatc gataccggtt tggacactca tgaatcctcg gaacgtatcc
     6841 acgctactag aggcataata agctagactt tctttctctc tgacattcat gaaaagttta
     6901 gagtgaggaa aaccgccaaa taaaccgtta aagaccatta gcgcaaaacg ttctggttca
     6961 tcgtaataca catttgtctg ataagctagg ttcagctttg cttgaacgat tggctcacgt
     7021 acttgtcgtt ccttcacgat attcacttga ggttgggtat aaaacagatc tggataaact
     7081 gtttcccgcg actcaaatgg taattgccca actgcttcag ctgctttgtc cggatcaaca
     7141 tcgccgacaa caaaaatgtc gatttgatca tttgccatca tttcttgata gtaggacgct
     7201 agcgaactag cagtgatctt gtccaaatct tcgactacgc ccaaccctgg gatcttttgt
     7261 tccgggctgt tttcaaaata aagttcttgc aaggcatagg aagcaaaagt ttgtttatct
     7321 tccttcaaac tttccaaata tagacgcaga ttgttctttt ccaagtcaaa cgtcaactga
     7381 tcaaactgat gatttttaat atttggataa aataaaacct cttttaaaaa atctaccgct
     7441 tgagaaaaaa ggtttggatc attgacatat tcaccattca caaaactgat ccctgcgttt
     7501 agccaatgta aatttccttt ttttctaact gataatccaa agcttgcgcc ataaagctct
     7561 gcaagttgcg cacttaactt tgtctgatcc gaataattca aactatttgt ttccaacatg
     7621 ctgctgagaa gtgaacgttt cgtgatgact tcttgttgca gacgcgcagt aaaacggata
     7681 aaaatccgga tcgttttgta ttgttttgtt ggtaagacat gaagattcac gccttctgcc
     7741 aattgataca ccatatttat atgctccttt tcacagttga ttgcccgctt actcttttaa
     7801 tgggtcaacc tgcctttttt acttattcct ctgcttgaaa tttataagtt caggcaattc
     7861 gccgtttttt ctaaatgatg ttacacttta tagtatagca tagatgtttt ttatcaaaag
     7921 aaacagacgg ctaaaagcgt atattgtttt tttatttttt atttttcgat atactaaaga
     7981 caaataaaag aagggagggt cattcatgat caaagaattc aaagagttca tcatgcgtgg
     8041 agatgtcttg gatcttgctg tcggcgttgt tattggtagt gcgtttacaa gcatcgtaaa
     8101 ccaagtggtg caaggcttga tcacaccact aataggttgg tttgtcgcaa tgatcacagg
     8161 tacttctgat ttagaaggag cactttcaat tcttgactgg tcgccgacaa aaggcgtcac
     8221 atttgcgttt ggtaacgtta ttagtgctat cattacattt ctgatcactg gttttgtctt
     8281 attcttagtt gtcaaagcgg caaaccgtgc gaagaattta cgctccaaag aagagcaagt
     8341 ggaagtggaa gaaactccta ctgcagaaga ttatcttagt gacatacgcg atcttcttgc
     8401 caaacaagtg gcagaagaca atacacatcc agtagagcaa acaaatcttt ccgatacttc
     8461 taaataataa agaatctaaa aaaaagaaag ccgattttca gtgtcggctt tcttttttta
     8521 gattcttaac ttgctacttg ttcctttttc atgtcgatat gtggaatatc atcttccaaa
     8581 tacacatctg agattgcctt gaatccaaac gactcataaa aagcttgtag gtattcttgt
     8641 gcgccgatca cgattggttt ttctggaaaa tttttctgga tcatgttaat cgtttcttga
     8701 acaatctttc ttcctaaacc atctttacgg ttgtcctgat gaacaaggac acgtccaaaa
     8761 tggatactct ccgcttcttc atatactcgc gtgtaggcaa ggatcttccc atcagtatct
     8821 tgaaaaaacg tatgccaagc ttctccatca atgtcatcaa cttcttgata aggacactgt
     8881 tgttccacaa caaaaactgc gattcgttct ttgacgatcg cgtaaaactc tgctgttgac
     8941 aattcttcaa atttctttac ctgatattcc actaagcaaa cgccccctgc ttttttattc
     9001 ttagcatacc gattcgcaca caaaaaagca aacgaacctt acgaatctca ggctcgtttg
     9061 ctttttaaac tgcttcagtt aaaaattcga tctcaactgt ccgagtaagt acatctgaat
     9121 agctgtaaga tactcgttca aaagaatttt cttcaggatc caaatcaaca acgaatactg
     9181 aaggataggt ttctgttaaa acgccgcggc gttctgtttg acgctttctt cctgtctgag
     9241 caaccaacat gattgggctg ccgatacgac cttctaaatc tttcttgatt gaagctaaag
     9301 ttgttggcat acagttcacc tctactatca actataccac a
//
LOCUS       DAZAOD010000099         9317 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000099 DAZAOD010000000
VERSION     DAZAOD010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.101"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(48..716)
                     /locus_tag="ACHDPO_002400"
     CDS             complement(48..716)
                     /locus_tag="ACHDPO_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFN3369988.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            850..1137
                     /locus_tag="ACHDPO_002401"
     CDS             850..1137
                     /locus_tag="ACHDPO_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3369989.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1553..3091
                     /locus_tag="ACHDPO_002402"
     CDS             1553..3091
                     /locus_tag="ACHDPO_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFN3369990.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3088..4053
                     /locus_tag="ACHDPO_002403"
     CDS             3088..4053
                     /locus_tag="ACHDPO_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369991.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4040..5362
                     /locus_tag="ACHDPO_002404"
     CDS             4040..5362
                     /locus_tag="ACHDPO_002404"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFN3369992.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5425..5529
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5603..6346
                     /locus_tag="ACHDPO_002405"
     CDS             5603..6346
                     /locus_tag="ACHDPO_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3369993.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6361..7353
                     /locus_tag="ACHDPO_002406"
     CDS             6361..7353
                     /locus_tag="ACHDPO_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFN3369994.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7365..8102
                     /locus_tag="ACHDPO_002407"
     CDS             7365..8102
                     /locus_tag="ACHDPO_002407"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3369995.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8092..8814
                     /locus_tag="ACHDPO_002408"
     CDS             8092..8814
                     /locus_tag="ACHDPO_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFN3369996.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8898..>9317)
                     /locus_tag="ACHDPO_002409"
     CDS             complement(8898..>9317)
                     /locus_tag="ACHDPO_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFN3369997.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3054 a         1605 c         1967 g         2691 t
ORIGIN      
        1 acataatgat atttctgtaa attaaataaa gtagtgaaaa ataagaatca gtgctctaac
       61 tgttcaagag gatcaagtgg ttcaaatgtt tctgtagtct gttttgcttc caattggggc
      121 aaaacagatc caatttccag atacttcact ttattcaatg tataagatag aatagaacag
      181 ctaagtaatg tatacagaaa atgtgtgaga tccaaataaa gcaaggagac aactaaaata
      241 ccaaaagtaa tcaagaaaag acttttgcca atcttaatat gaaaatattt ttcaatggct
      301 tgataaatga tatctgttcc gcctgtgctt ccgccgaatc gaaagacgag accgcaacca
      361 atgccagaaa gaatacctgt catcaaacta ttgatcagta gactatctac agcaaaatgt
      421 atatgaaggc tctcccataa atgtaaaaag aaaactagcg caaatgttcc gacgatcgtc
      481 cggagaaaag cgtgttttcc aaaaagaaac aatgagataa gcaataaagg taaattaaaa
      541 agcagtgaag tgacagaagg agcgaatcca aaaagattat gcaaaagcaa agcaatacca
      601 gtaaccccac catctgccag cttagatgga atattgattc ctgtcacagc taatccgtag
      661 attcctgcgc ctaaaatgat tccgcacaat tctgtaaata aatttaattt tttcatttct
      721 agcctctttt cttttgaaaa ttttcagcaa cttctttatt atactgactt atactcttac
      781 ttcaagagga aaatgaaaaa aaattatttt tggctgtttc tttttattta tcaaataagg
      841 agtggaaaaa tgcgagcagc agacttattg acaattctta caaaatcacc caaaaaaaca
      901 gagtatcaag gagttttttt ggctcaagaa caaaaactgg tgcctgtgac aatggtccag
      961 ataaataaag caaatcaatt tatcttttta tttgaacacg gcaaagcacc acttgctatg
     1021 aaagacatct ttcttttttt gatgaagaac cgtgagaaag ctgtttatta tcagtcaaaa
     1081 gaagaactca ttcctcttta tggagtgaaa gagatagaaa ataaagtggt gatataagta
     1141 aaaataagaa aacaagacgt ttatgatgtc aaaacaacca ttttttacat ttttggcaaa
     1201 aaagtgtcat gatacagtat aatattcgtt gaacaggcca ataaaggtgt tctcccccac
     1261 gagatttcta ctttattggc tgtttctttt tattaaaata aaagttgtgt gtgtaaaaaa
     1321 gatatagctg attccaagtg acaatttcgt atagattttt atggtattcg tagtgaaaaa
     1381 acgagaacca aaaagttgat ccgactttgt tgcttggatt ctttttttgt cagcatattt
     1441 agaggtattt ttttcttttt tttgttcgtg ctgtaaggtt aaggcaagac aagttagttg
     1501 ggaaaaagga aagaaatgtt tatacttaaa gaataacaga aaggaaggtc gcatgaataa
     1561 ttttatacaa acattaagtg aaagaaaagg cgagttgctg gaagctgcat ttcaacatct
     1621 gtccatttct ctcatttctt tgctgattgc agcactgatt gctattcctt tagcgatttg
     1681 ggcagccaat cataaaaaaa tggcagaagt cttattgcag atcacgggtg tgctccaaac
     1741 gattccttca cttgccttat taggtttact tatcccattt gtagggatcg gaactgttcc
     1801 agcattgatt gcacttgtta tttacgcttt gcttccgatt ttccaaaaca cgtatattgg
     1861 tctagctgaa attgacccgt ctattgaaga agcagcggta gcatttggta tgtccagaat
     1921 gagacgcttg ctgaaagtag agcttcccat cgcattacct gtcattatct caggtatccg
     1981 aactgcctta gttttaatca tcggtacggc tactttggca gcattgatcg gagcaggtgg
     2041 attagggaca tttattttgt taggtattga ccgaaataca cctgttttga cattgattgg
     2101 tgcgatcagt tctgccttgc ttgcaattat attcagcgga ctgattcgct ggttgcagca
     2161 taagaaacct cgatattcca tcattacttt agcagcagtg gtgtgtttat ttggcggcgt
     2221 ttctttatat cagtctgcct tgtttaaaaa tgaaaccatc acgattgctg gaaaattagg
     2281 agcggaacct gaaatcctga tccaaatgta taaagaattg attgaagaca acacaaaaac
     2341 agaagttgaa ttaaaaccga attttggcaa gacgagtttt ttgttcaatg cactggatca
     2401 aggtcaaatc gatatctatc ctgagttcac aggtactgtc ctagaaagct tggtgaaggt
     2461 acctgaagca atgaaaagtg ctgatttgac aaaagaaaaa acatatgacg aagcagaaga
     2521 attattgaat aagcaattcg atatgacatt attaaaacca atggcttacc aaaatacgta
     2581 tgccttggca gtcaagagat cttttgcgaa cgaacatcaa cttaaaaaga tttccgattt
     2641 ggcagctatc tctgatcaga tcaaagcggg attcacactg gaatttattg atcgttcaga
     2701 tggatataaa ggaatccaag aagcatatgg cttgaatttt tcaagtgtac aaagcatgga
     2761 gccaagtttg cgttaccaag caatcaataa tggagatgtc aatattgtgg atgcctattc
     2821 cacagatagc cagctcaagg agtacgatct agtgactcta gaagatgatc gagggttatt
     2881 cccagcttat caaggcgcac cgctgatgaa aaaagatttt gctaaagaac atcctgaaat
     2941 cgttaaagca ctgaataaat taagcggaaa aataacagag gatcaaatga ttgatatgaa
     3001 ttaccaagtc aatgtcgaaa agaaaaagcc gacagaagta gcacgaatct tcctgaaaaa
     3061 tgaaggatta gtaaaggagg aagatcagtg actaaattaa tcgagttcaa acatgtgcaa
     3121 aaaaagtatg atggaaagta tgtcatcgat gacctaaatc tggcaatcaa aaaaggagaa
     3181 atctttgttt tggttggtcc ttccggtagt ggaaaaacaa ctactttgaa aatgatcaat
     3241 ggattatcta aaccatcagc aggagacatc tacttcaaag gaaaatcgtt aaatgaatat
     3301 aatctgcaga aaatgcggtg gaatatggga tatgtgctgc agcaaatcgc tttgttcccg
     3361 accatgacag tcaagcaaaa tattgaagtc atccctgaaa tgttaggttg ggaaaagcag
     3421 aaaagagcag accgtgtaga tgaacttctt caaaaagttg gcttatctcc tgatatttat
     3481 cgagatcgta tgcctagaga gttgtctgga ggagaacagc aacggatcgg gatcatccga
     3541 gctattgctg caagcccaga tgtgattttg atggacgagc catttagcgc attagatccg
     3601 atttcaagaa actcattaca agaattggtt ttgtccttac acgaagaatt gggcacgacc
     3661 atcgttttcg ttacgcacaa tatggaagaa gcaatcaagc taggtgatcg tattgcattt
     3721 atgaaggatg gagaaattat ccaatgtgac acaccagagc agttattgat gaatcctaaa
     3781 aacgactacg ttcggcattt ctttgatgaa ccgaaacaga cgaaagagtg gcgagtagaa
     3841 gatttagtcg tcaatggata tttcttaaat gaaataccag aaaatgctcg tcaacaagtt
     3901 tgctttgata cgcctatgaa agaagtatat tcgcttcttt cggtgtatcc aagcattgtg
     3961 atagtagaaa agcaaagaag tattgggtcg ctgacaagta aagaaatctt tgctttttta
     4021 agtcgagagg aggaaggaaa tgaaaacata tgatgcaatc atcatcggtt caggtgtgag
     4081 cggcttaagt gctgcttatg gattgaaaga agcaggtaaa acagtactag tggtcgaaga
     4141 agatctatgg ggcgggactt gtcctaaccg tggatgtgat cctaaaaaag tcttgttaag
     4201 tgcagtagag gcacgtaatc gggtaaaaca attgagtgga aaaggtttta acgagatccc
     4261 aactgccaac tgggaagaac ttcaaaaatt caaacgaaca tttacggatc cagtcccaga
     4321 aagccgaaaa aaacaattag cagaagctga aatcgatcat ctttcaggaa ccgctcgttt
     4381 tttggatgat tcatctattg aagtcaacga agaagtcttc catgcggatt acttagtttt
     4441 ggcaaccggg caaagaccta cgatcttacc agtggaggga aaggaatact tgaaaactag
     4501 tgcagacttt ttatcattgc ctgtactgcc taaagaaatc atttttatcg gtggtggtta
     4561 tattgctttt gagctagcta cgattgccaa tgctgcaggg agcaaagtaa ccattgtcca
     4621 tcataatcaa cggccattaa aagaatttga ggcgtctttg gtagaggaag ccgtccatca
     4681 aatggaagca tctggcattc agtttgcttt tggtgttgaa acccaaaaga tcatttcaga
     4741 aggtactcgc tatcgtttag tcggaaaaga gacggaatta gtagcagata tgattttttg
     4801 tgcgactggg agacagccga atacagaatc tttagcactt gagcaagcga atatcgtctt
     4861 tgataaacac ggaattgcag tcaatgatta tctgcaaacg agcaatccaa aaatttttgc
     4921 gtgtggagat attgtttcaa ggaaaacccc aaaattgaca ccagtcgcca cttttgaagg
     4981 aaattatgta gctaagcgga taacggatgc aacaagcgaa cctatcaaat atccgattat
     5041 acctacgatc gtctacgcca gtcctaaact tgctgaagta ggagttacaa aaagtcacgc
     5101 ctcttcgtca gatcaagtgg tagagatgga tcttaccagt tggttcacct atcatcgtgt
     5161 caatgaacca gttgctaagg ctgaattgac ctttgaccag caaaattatt tgattggtgc
     5221 tgcagtgatt agcgagcaag cagacgaatt gatcgatgat ttgacactcg tcatcaatca
     5281 aaaattgact aaaaaagagt tggatagcta tatcatgggg tatccgacat tggcaagtga
     5341 tctctcctat ttattgaaat aatcagcatg ataactaaag cgcttgttgc tttttccttc
     5401 ttgtgctaca ctttaaaaaa tgaatacctg tttctgggga tgtcgtagac gacatgagag
     5461 taagttgtga acttagaccc attgaacctg tcagttaata ctggtgaagg gagaaacata
     5521 gcagacgctt gaagcgggtt actatgtcgt gcccatttca agcgtttttt gttattcata
     5581 ttagaagaaa ggaggtaaca aaatgaagaa aaatctttat ccagcagtca gtatggcatt
     5641 cattttaatt atttggcaga ttgttgtcat agtttggaaa atacctgcct ttattttacc
     5701 cggacctgct gctgtatttt ctgcattagc ggcagatgca caagtattac tttcccattc
     5761 tgtcacgaca ttaaatgaag cagtgcttgg tttggtaata gctagcgttc tttcttttat
     5821 tactgccttg gcaatggatt attggaagtt tttagaaatg tctttttatc cgttactagt
     5881 gatttcacaa atgttgccaa tcatggtgtt agggccatta cttaccctat ggtttggttt
     5941 cggtatgctt ccaaaagtga tccttgttgt cttgataagc tattttccga tcgtagtttc
     6001 tttttcggat acattgagga aagtatcaaa agagcaaatc atctttttga aaacgatggg
     6061 ggcagataca gggaagattt atcgaatata taaaatacca gcgggtttat ccggcttctt
     6121 ttccggttta aaagtggctg ctacttattg tgtcagcgga gcagtcgttg gagaatggct
     6181 aagcgctcaa gcaggcttag ggtattacat gatacgcgta aaaaacagct accagatcga
     6241 taaagttttt gctgcgatca tttgtgtcat tctattgagt ttattgctga atggcgcttg
     6301 ttcattattg aaaaaagggt attatcgtat gctttatatt ttttaagaga aggggatcaa
     6361 atgaaaaaat tatggctttt attaccgcta ctgttgcttt tatccgcttg tggcactgca
     6421 aaagaaacaa gtagcaaaca agaaataaag gatttgaaaa aagtgacact tgttttggat
     6481 tatgtaccga atactaatca tactggcatc tacctagcaa aagaaaaagg ctattataaa
     6541 gaggctggtt taaatgtcca aatcatcgaa ccaggagata attcgacaag tattggtcta
     6601 gtaggtgcgg acaaagcaca atttggtgta agttatcaag aagatgtcac ttatgctcac
     6661 gcagatggac agaatatacc agtcaaagca attgctacag tgatcaaaca taatacttct
     6721 ggattcgcca ccctatcaga cagtaacatc cattcaccaa aagattttga aggaaaaaca
     6781 tatgcaggtt ggcaaagtcc aagtgaagaa gctgtcttaa aagctgtgat ggaaaaagac
     6841 ggcggggact tttcaaaact gacaatggta ggaagcaatg gagaagggcc agaaagctta
     6901 ggaaaatcct cagatatcca atggtacttt gaaggttggg atatgatcaa agcaaaagaa
     6961 gcgggtattg aactaaacta tatcccattg aaagaattag atgaacggtt agattactat
     7021 actccggtaa ttattacgaa tgatcaactg atcaaaagtg atccagaatt ggtacagtct
     7081 tttatggatg ccacgaaaaa aggctatcag gaagctatta aggatccaaa tgacagtgct
     7141 aaactgttgc aaaaatatgc aaaagaaaat gatcggacgt ttttagaaga atcacaagca
     7201 ttcttgtcaa aaaattatac ggatgatcct gagaattggg gattgatgga agaaaaagtt
     7261 tggcgcaatt atacagcttt tatgcaggaa aacggattga tcaagcaaga tgtaccttcg
     7321 caagaactat tcactaatca gtttataaaa taggagtgat agatatgtca atccaaatca
     7381 gccacttgaa tgtagtcatt gaaaacctga aaatattaga agacatccat ttcactatcc
     7441 ctaaagatac ctttacatcg attgtcgcgc caagcggagc cggtaagtca acattgctga
     7501 aaactttaac aggagtccag cctatgactt ctggaacgat caaagtagac gatcaaaaag
     7561 taactggtct ccatacagca tttagttata tgccgcaaga agatatgtta cttccttggc
     7621 tgagcgtcta tcaaaacgtt acgttatatc aaaaaatcaa tcatctaaca atcaatgaag
     7681 aacaagtaag ggattatctg gatatctttg ggttaaacgg ctatgaacat tttttgccgg
     7741 aacaattatc tggcgggatg aagcagcgaa cggccttgtt acgaacaatc atgaatcctt
     7801 cttcttactt gcttcttgat gaaccatttg gagcgttaga tgctatgacc agagggcaga
     7861 tgcaagactg gatgttgaag ctgcctaaaa aagcaaagcg gactacttta cttgtgacgc
     7921 atgatatcga agaagcaatt tatttatcag acaggattct tgtgctttcc gcccgtccgg
     7981 cacatgtgat tgctgagatt caagtgcctg aaaaacgacg gtcacgtgaa tggctactgc
     8041 agcaatcaga gttgaagcaa acgatttatc agttattggc aggtgaatta gatgttaagt
     8101 gatgctcatt gtcatttaga tgggagtcag agtttagcac tccttcagca ggaacacacg
     8161 attttgacga tcatcaattg tgattcgcca gaagaatgga aggaaaacag acagcttgca
     8221 gcaagtaaga ctcaagcctt aagttacggt atccatcctt ggaaagcaga tagctatacg
     8281 tttgaacaag ttgagccttt tttgaaaaaa gcaaggatca tcggtgaaat agggttagat
     8341 aatatttgga cgaatgtacc gatgactaca caaaaaaaag tatttgagcg acagcttgct
     8401 tttgcagcca taaatgagaa acctgttgta ctgcacacaa aaggatgcga aaaagagatc
     8461 ttaaattata tccaagctta ccctaatcac tatttgatcc attggtattc ttctttggac
     8521 tatcaacaag actatattga tttaggctgt tatttcagca ttggtcttga tttgaaaaag
     8581 aatccagcag tctggcaact agctaaagca gtcccaatcg accacttact tattgaaacg
     8641 gatggactac atgcagcaga gtgggcttta ggggggattt tttcagaaaa agattatgtc
     8701 tcactgcttg aagaacagtt aaagacaatc gctgagatca aagagctatc agttgaagaa
     8761 gttaaaaaaa atacttatca aaacttggaa cgtttcatta gattaggtaa ataaaaaaga
     8821 gatgtgacac aactagtgtc gcacctcttt ttggctttct ttgtataaaa gtaaactgtt
     8881 tgattaataa atgaatctta gtaccaaccg tttgcttccc agaatgcttt cgccgcttcc
     8941 caagaaccat aacgtgaagt aacatattgt tctgctactc tttcttggtt tgcagcagag
     9001 tagtcaccat ttaagtaaga agaatctaat tggtaacgtc cgatgtaacg tccgttcgtt
     9061 gctgtgtaag aaccgcttga ttctttttgt gcgatccatt cttttgcaga gcttgtgctt
     9121 gctggagtag cagcagtttc tgttacagca ggagcaggtt gtgtttcagc aacaggcgct
     9181 gcttgttttt ccgtttgaac cgtttcttgt acaacaggtt gttcagcttg gactggtgct
     9241 tcttgaacgg ctgcttgagg ttcagcagct gcttgtgcag agccttctgt tgggattgtt
     9301 aattgttgtc ctgagta
//
LOCUS       DAZAOD010000100         9089 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000100 DAZAOD010000000
VERSION     DAZAOD010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.102"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            193..417
                     /gene="nrdH"
                     /locus_tag="ACHDPO_002410"
     CDS             193..417
                     /gene="nrdH"
                     /locus_tag="ACHDPO_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFN3369998.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            576..2735
                     /gene="nrdE"
                     /locus_tag="ACHDPO_002411"
     CDS             576..2735
                     /gene="nrdE"
                     /locus_tag="ACHDPO_002411"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFN3369999.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            2785..3750
                     /gene="nrdF"
                     /locus_tag="ACHDPO_002412"
     CDS             2785..3750
                     /gene="nrdF"
                     /locus_tag="ACHDPO_002412"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFN3370000.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(3839..4978)
                     /locus_tag="ACHDPO_002413"
     CDS             complement(3839..4978)
                     /locus_tag="ACHDPO_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFN3370001.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(5287..6000)
                     /locus_tag="ACHDPO_002414"
     CDS             complement(5287..6000)
                     /locus_tag="ACHDPO_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFN3370002.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(6254..6955)
                     /gene="nagB"
                     /locus_tag="ACHDPO_002415"
     CDS             complement(6254..6955)
                     /gene="nagB"
                     /locus_tag="ACHDPO_002415"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFN3370003.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            7189..8721
                     /locus_tag="ACHDPO_002416"
     CDS             7189..8721
                     /locus_tag="ACHDPO_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFN3370004.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(8912..>9089)
                     /locus_tag="ACHDPO_002417"
     CDS             complement(8912..>9089)
                     /locus_tag="ACHDPO_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3370005.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         3028 a         1771 c         1590 g         2700 t
ORIGIN      
        1 acaatttttt ctctattaaa tttgctattt tcccacacga tacttgtttt cagctctttt
       61 ttcaaaaaca caaaacttag tattccacag tttccacaac acaatatgta gtgtttgttg
      121 tttgactttt ttactaagag ttttatacta tctattatag ataataagaa tgtgttagag
      181 gaggcactca ccatgaacgt aaaaatcttt tctaaaaata attgtatgca atgtaagatg
      241 gtcaaacggt ttttaacaga aaatcaaatt gcttttgaag aagtcaatat cgatgaacag
      301 cctgaagcag tagactggtt gaaagcacaa ggattccaaa gtgttcctgt cattacttct
      361 gatgcagaaa cagttatcgg attccgtcct gatcagttgc gtaaacttgc cagctaacat
      421 gactaaaaga atcaaaacgt gatacatgga tttgaagggc ttgagacagc accagttttt
      481 gtcgcaaact tccaaatcct tttttaaagc ttaaaaacaa tgcaatgatt tgcaatcaag
      541 catcatcaaa tacgaaatga aggttgggcg tacgtatgag tcttaaaaat ttacaagatg
      601 tcagttattt caagctgaat aatgaaatca atcggccagt caatggtcaa atccctttga
      661 ataaggataa agaagcttta gttgcctttt ttgaggaaaa tgtcaaacca aatacgatga
      721 cttttccatc tattatggaa aaaatcaatt acttgatcga tcaagaatat atagaagcag
      781 aattcattca attgtattca ccatcattta ttgaaaagct atatcaattt ttggacgagc
      841 aacatttttc tttcaaatct tttatggctg cttacaaatt ttattctcaa tatgcgttga
      901 aaaccaacga cggttccgct tatctggaaa cttatgaaga tcgagtagcc ttcaatgcgc
      961 tttactttgc gaacggggat gaagaattag cacttgctct tgcagacgaa atgatccatc
     1021 aacgatatca gccagctaca ccttctttct tgaatgctgg acgtaaacgt cggggcgaat
     1081 tggtgtcttg tttcttgact caagtcactg acgatatgaa ctctatcggg cgctcaatca
     1141 actctgcttt gcaattgtcc cgtattggtg gcggcgtagg gattacttta tcaaatcttc
     1201 gtgaagccgg cgctcctatc aaaggatatg agggtgctgc aagtggtgtc gttccagtca
     1261 tgaaattatt cgaagatagt ttcagctatt ctaatcaatt aggtcagcgt caaggagctg
     1321 gcgtggttta tttgaacgtt ttccatccag acattattgc tttcctttca gcaaaaaaag
     1381 aaaatgcaga tgaaaagatt cgcgtaaaaa ctctttctct tggcgtgatc gtacctgata
     1441 aattttatga attgacacgt aaaaacgaag atatgtattt atttagtcca tatagtgtcg
     1501 aaaaagaata tggtgtccca ttctcttatg taaatattac agctgagtat gatcatctag
     1561 ttgcaaatcc aaacattcgc aaacaaaaaa tcaaagcgcg tgatcttgaa aatgaaatct
     1621 caaaattaca acaagaatct ggctatcctt acgtaatcaa tattgataca gcgaaccgcg
     1681 agaatccaat cgatggcaag atcatcatga gtaatttatg ttcagagatt ttacaagttc
     1741 aaacgccttc tgtgattaac ggcaaacagg aatatgaagt attaggaaca gatatctcat
     1801 gtaacttagg ctcgacaaat atcgtgaatt tgatgcaaag ccctaacttt ggtcaatctg
     1861 tgcgtacgat gactcgtgca ttgacattta ttacagatgc atctgatatc gatgtcgtac
     1921 caccgatcca aaacggaaat aagctgaatc atacgattgg attaggtgcc atgggcttac
     1981 acacttatct tgcaaaagaa caaatggaat atggctcaga ggattcatta gactttacaa
     2041 atatttactt catgctgttg aattattgga cacttgttga aagcaacaat atcgctcgtg
     2101 aaagaaaaca agttttccat aattttgaaa aatcagctta tgctgacggc acttatttcg
     2161 aaaaatacgt aactggagaa ttccagccaa aatcagaaaa agtcaaagca ttgtttgaag
     2221 gcatttttat cccaactgct gaagattgga atgctttgaa acaagcagta atgaaagatg
     2281 gactgtatca tcaaaatcgc ttggcagtag caccaaatgg ctcaatttca tatatcaacg
     2341 atacgagtgc aagtattcat cctatcactc gcatgatcga agaacgccaa gagaagaaaa
     2401 tcggtaaaat ttattaccca gcgccttatc tatccaatga gacgattccg tattacactt
     2461 ctgcttatga tatggacatg cgtaaagtaa tcgatgttta tgcaacggca caacaacacg
     2521 tcgatcaagg catgagtttg actttattca tgcgttctga aatcccagaa ggcatttatg
     2581 aatggaagac aacaacgaag caaacgacac gtgatttgaa tattttaaga cattacgctt
     2641 tccacaaagg aatcaaatcc atttattacg tacgtacctt tactgatgat gcagaagaaa
     2701 tcggaagcaa tcaatgtgaa agctgcgtga tctaatatca tagatagatt cgcttattca
     2761 tattttaatt aaaggagcat tctcatgtca gaaacatatt atgaagcaat aaactggaat
     2821 gaaattgaag atatcattga taaatccact tgggagaagc tgacagagca attttggcta
     2881 gatacacgta tcccactttc aaatgaccta gatgattggc gtacattgtc tcaattggaa
     2941 aaagatacag taggacatgt atttggcggt ttgacactgc tagatactgt ccaatctgaa
     3001 agtggcatgg atcagttgcg taaagatgtc cgcactcccc atgaagaagc cgttttgaac
     3061 aatattcaat tcatggaatc cgttcatgcc aaaagttatt cttctatttt tagtacactg
     3121 aatacgaaaa aagaaatcga agaaattttt gactggacaa atacgaatcc ttatctgcaa
     3181 aaaaaagctg agcgtatcaa tgaaatctac aaacacggta caccgctaga aaagaaaatt
     3241 gccagcgtct ttttagaaac attcttgttc tattcaggtt tttatactcc tctttattat
     3301 ttaggaaaca acaaattggc taacgtagca gagatcatca aactaatcat ccgagatgaa
     3361 tctgtacatg gaacctacat cggttacaaa ttccaattag gattcaacga gttacctgaa
     3421 gcagaacaag aaacgttaaa agactggatg tacaatcttc tttatgagct ttacgaaaac
     3481 gaagaacgtt atacagaaga attatacgat ccaatcggct ggacagaaga agtcaagaca
     3541 ttcctacgct ataatgccaa caaagcattg atgaacctag ggatggatcc actctttcca
     3601 gatactgcca atgatgtcaa cccaatcgta atgaacggga tttcaacagg cacaagcaac
     3661 catgacttct tctcacaagt cggaaacggc tatttgttag gtcatgtaga agcgatgaaa
     3721 gacgacgatt atttgattgg attggaataa ggatttattt taattcaaaa atttttcgaa
     3781 aaataaaaag agtttagcgt acagatattt taaatgtaca ctgaactctt ttttatgctt
     3841 attcacttgt ttcttccagc acttttggac tgtctaactt ttccgaaaca tgttccattc
     3901 ttctcaataa atagattttc cggatattta atattatcgt cttaatcact gcatagacag
     3961 gtatgcaaat cagcatgcct aatattcctg cgacacttcc tgctccaatc aataccaaga
     4021 tgatcgtcaa aggatggata ttcattgatt tcccaaataa caacggcttg atcaaatttc
     4081 catctaattg ttggatcact aaaatcgaca acgccatata caaagcttga aatggagaga
     4141 taaacaaacc gacaatgatt gctggtaccg ctccaataaa agggccgaca tacgggataa
     4201 tattcgtgat tccgcaaatg accgcaagca acaagctata aggctgatcg aatattctca
     4261 ttgccaaaaa gctcattaca ccaataatca aagcatctaa gatcgtactg ctgatatagg
     4321 cagataatgt ttcgtttaat tcttttaccg tttggcgtaa ctctttacga atcgctttcg
     4381 gaaagaagtg agacaacgca tcaataaatt tgtgcccatc cttgaacata aatagcaaaa
     4441 taaatggaac ggtaaataac aaaataaaaa attgcatcat aaatgaaatg atttttgaga
     4501 cacttgcaga taaactgact aatatgatat tgaacaaatt actaagagat aaatttgctg
     4561 atgctaattg ttcttccaaa ttgaaatttt taaactcttc ccgctgcgcc aattcattta
     4621 accatttgct tgtttcatct gcatacattg gcaagctctg ggtcaattga attgtctgtt
     4681 ccattaactg aggcactaca ttcatgacag ttaaaacaac taaaatgatt acgaccaaaa
     4741 acgtcaataa aaaaccgaac actctcggga tccgatgctt ttcgagaaaa acaacgattg
     4801 gatcgaacat ataatagata aaaccagcaa caagcaatgg taaaaaaatt gccgaaagca
     4861 ttttcaatat tggactaaaa atattcggca tttgtaaaat aaagtacacg ccgatgatcg
     4921 tgagtactag ctccactgtc cagaaaaata attttgattg tttaaaacgt gattgcatac
     4981 atctcctcca aggtcctttg atacttctat tctatcattt aacaaagagt tacgcgctga
     5041 gattttcatt tgcttaaaaa aaacaaaaaa aataaacata ttttaatgag tagacgagta
     5101 cttaaacaaa aacacggttt ggagtagtga caaaaattat actgcagtcc ctttttccaa
     5161 ataaacggtg ttcaaaagct tgcatcttcg taataagccc agccaaacga aaaatataag
     5221 gaactatttt tatttggctg ggcttattac ttgatgtagg acatctattt tacaacctca
     5281 gatcatttat tgcgcaatac tgactaaatg caactttgtg atatttttgt gtacggacaa
     5341 ctcctcgatc acatcggcat aagtgagccc ttttggaaga tcaatcgtat agatattttt
     5401 gtacactcgg tagtcatcaa cgaattttac gtcaaaattc acatcttcga ttacgatatt
     5461 tttctcttca aaataatcgg taagaaaatc tttggtttct tttctatgga taaattggat
     5521 ttctaacttt ttagtcgtag gtacatggat cacgcgtttc actactgtga gtgcaatagc
     5581 aatcccgata aaactgatga tcgcaatgga atagtaaccc atgccgatgg cgatccctaa
     5641 tccagcaatt gcccataaag aagcggcagt cgtaagtccc gtcaccgatt gtttcgtgac
     5701 gatgatcgtt cccgcgccta agaaaccgac accactcacc acttgagcaa tcagccttgc
     5761 ttcatctgaa cgaatcgttc cagcaagctg tggatactct aaagcatctc ttaatgcacc
     5821 actagcgatc tcaacttgga tcaatgcaat gatacatgct cccatacaaa ctaaaatatg
     5881 cgtacgcata cctgctggac gatttttata ttgtcgttca aaaccgattg ctccgccaaa
     5941 tagcatagcg atccctaaac gtaaaataat ctctggaatt gtcaatacca tatcattcat
     6001 ctaaacaccc tccagtccaa tatatcatgt ctgaaaggag cagacaaaaa aagtgcaatt
     6061 tttacctctt acgaaaaaag gactgtgaca aaatttttgt catagtcctt tttatgaata
     6121 aacggtgttc aatcagctga ccctcggtat tactcaacaa acggcaaaat atggggagct
     6181 atttttcctt tgtcttctct aatactcagg tcaaaacgct gatttcacaa cctctttagc
     6241 ctactattga aaattacaac ttacttgctg cttcttcatc gatgatcaca acaacattgt
     6301 cgtgattttg caatacactt gctggcaaat gattcgttac aggtccttca atcatccctt
     6361 tgattgcatc agctttgctt tcgccaaatg ccatcaagac gatttcttta cttttcataa
     6421 ttgaaccgat tcccattgaa acagcttttg ttggtacatc ttctgcttta tcgaagaatc
     6481 gtttgtttgc attgattgtt gattctgtta agtcaactac tgaagtcgtt ccgtcaaatg
     6541 aagcaccagg ttcattgaaa ccgatatgtc cattttgccc gattcctaag atttggatat
     6601 cgattggatg tgcatcgatg atttgatcat actttttgca tgctgcttcc agatcttctg
     6661 cttttccatc tggtacaaac gtttctttga atggtttttt atcaaataat tggacatcca
     6721 tgaaatgacg gtagctttgt tcatctgaac cgcctagtcc aacgtactca tctaagttta
     6781 cagaagtcat ttcactgaaa tccaaatcgc ttgaagtcat ttctttatat aaagtaactg
     6841 gtgtgcttcc tgttgccaat cctaatactt ttgcaccttt gttcatacct tctttgatga
     6901 tttcaaatgc tttttttccg ccttcttcag cgttttttac acgaatgatt tccatagtga
     6961 ttgctccttt atattttggt atagcccaat tatagcattc tttttttctt tttacaataa
     7021 ttagtataga ccaaattgca tttttttcat tttcttgaca ataaatagga atccgtgtta
     7081 ggtttcataa gatggttcaa tcaaacaatc catgttgcat gaaaaccaag caagtgattc
     7141 actgtggacg ctttatgtct gcagtttttt tatgaaaaag gagttattat gagtatactg
     7201 acattaaaca acattaccca gcaatttggc gacaaaatcc tctatgaagg tgtcgatctg
     7261 caattaaatg ctggcgaaca tcttgggctg attggacaaa acggagccgg taaaagtaca
     7321 ttgattaaaa tcatcactgg tgagatctta ccagatgacg gacagatcca ttggcaaaaa
     7381 aatattcaca aaggttacct cgatcaatat gtggaagtcg atgaaacatt aacaatcgaa
     7441 gaatttctaa aaactgcgta cgcaaaagaa tacgaaaagg aagaaaaaat tgcttttctt
     7501 taccaaacat atagcgagac cttcgatgat tccttgctgg aaaaagctgg gaaactccaa
     7561 acggaattag accaaggagt gttttatcaa atcgacacct tagttgctga gatgagcagc
     7621 gggttgggga tcgatgtctt aggtttagat tcactgttga aaaatctaag tggtggacaa
     7681 cgttcaaagg tgattttagc aaaactactt ttagaaaacc cagatgttct gatcttagat
     7741 gaaccaacca atcacttaga tgatcagcat atccaatggc tgacgcagtt tcttcaggat
     7801 tttgacggtg cgtatatcgt gatttcccat gaccaagaat ttcttgatca gatcaccacc
     7861 catatcgcag acatcgagtt tggaaagatt actaagtata ctggccatct aaaacaagca
     7921 ttgaaacaaa aggaacaaaa tcgcgaaagc tatttgcgcc aatatcatgc tcaacaaaaa
     7981 caaatcgaaa agaccgaagc ttatattcga aaatacaaag ccggttcccg atcaacgatg
     8041 gcaaaaagcc gacaaaaaca attagataaa atcgaacggc tgacgcctcc agcttcagca
     8101 agtaaagctg tctttgattt tccattctcg cctattgtca cgacattagc agtggaaaca
     8161 actgatttag tcatcggata tgatcgaccg ctacttgcac ccatcaattt gaccatccgc
     8221 tttggtgaaa atattgccat tcgaggcttc aacgggattg gaaaatctac tttattaaaa
     8281 acactgatcg gtgagattga aaaaataagt ggcgatttcc acttcccaga taacacaaaa
     8341 atcaattact tttcacaaga tctgtactgg gaaaatccat tagaaacacc actacaatat
     8401 ttaagcagtc aatttccaaa agcgactatc aaagaattac gtcgccaact agctaaagca
     8461 gggttagtta atcaattagc aagtgaacct ctcactacat taagtggtgg ggaacaaact
     8521 aaggtgaaac ttgcacagtt gacaatgaac caaggtaatt tactgattct cgatgaaccg
     8581 acgaaccata tcgatcaaga aacgaaagaa agcttacaag acgggataca gaaatttcca
     8641 ggaacagtaa tcatcgtctc tcatgaacaa gaattttatc aagatcttgt gcaacgagtc
     8701 attgagattg aaccaaaata aacgtttgat tgaatagttg aaaaaaagga gctgtgacaa
     8761 aagttttgtc acaactcctt cttctgaata aatggtggcc aattagctga ccttcggtat
     8821 tagctcaaaa aacggcaaaa tatgaggagc tatttttatt tggctattct tattacttga
     8881 tgcagaacag cttttcacaa cctcttttcg tctatttttt attttcgaga tttctctttc
     8941 ctttaaaaac aactgtttga aagaagaacg cacatccttg aaaaacaagc ccgctaaccg
     9001 ttacacctaa ccagccatac tgctgccaca ttgtcgtccc tagcaatgaa ccagccgcac
     9061 ctccaataaa gtacataaac ataaataca
//
LOCUS       DAZAOD010000101         9041 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000101 DAZAOD010000000
VERSION     DAZAOD010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9041
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.103"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..107
                     /locus_tag="ACHDPO_002418"
     CDS             <1..107
                     /locus_tag="ACHDPO_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HFN3370006.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(176..904)
                     /locus_tag="ACHDPO_002419"
     CDS             complement(176..904)
                     /locus_tag="ACHDPO_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFN3370007.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(917..2197)
                     /locus_tag="ACHDPO_002420"
     CDS             complement(917..2197)
                     /locus_tag="ACHDPO_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFN3370008.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2338..2940)
                     /locus_tag="ACHDPO_002421"
     CDS             complement(2338..2940)
                     /locus_tag="ACHDPO_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFN3370009.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3185..3391
                     /locus_tag="ACHDPO_002422"
     CDS             3185..3391
                     /locus_tag="ACHDPO_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370010.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3703..4422
                     /locus_tag="ACHDPO_002423"
     CDS             3703..4422
                     /locus_tag="ACHDPO_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFN3370011.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4503..5186)
                     /locus_tag="ACHDPO_002424"
     CDS             complement(4503..5186)
                     /locus_tag="ACHDPO_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFN3370012.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5405..7591
                     /locus_tag="ACHDPO_002425"
     CDS             5405..7591
                     /locus_tag="ACHDPO_002425"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFN3370013.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            7937..8347
                     /locus_tag="ACHDPO_002426"
     CDS             7937..8347
                     /locus_tag="ACHDPO_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFN3370014.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            8361..8717
                     /locus_tag="ACHDPO_002427"
     CDS             8361..8717
                     /locus_tag="ACHDPO_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFN3370015.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         3243 a         1483 c         1697 g         2618 t
ORIGIN      
        1 gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag
       61 atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga
      121 accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg
      181 aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga
      241 cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat
      301 gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta
      361 attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat
      421 attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat
      481 ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat
      541 tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt
      601 ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat
      661 ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga
      721 tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt
      781 ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt
      841 tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa
      901 tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt
      961 caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca
     1021 agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt
     1081 ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct
     1141 tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt
     1201 ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg
     1261 gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg
     1321 acagtaaact acggatctca ggaactttca tattatccaa catacttaga ttggccggaa
     1381 aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt
     1441 ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt
     1501 tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc
     1561 tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc caataataaa
     1621 ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga
     1681 catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata
     1741 tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg
     1801 atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat
     1861 actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc
     1921 ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt
     1981 gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag
     2041 cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga
     2101 ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt
     2161 aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt
     2221 taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca
     2281 gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta
     2341 atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag
     2401 caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga
     2461 gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg
     2521 gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag
     2581 taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag
     2641 atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa
     2701 ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt
     2761 gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt
     2821 tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc
     2881 ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat
     2941 ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc
     3001 ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca
     3061 agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg
     3121 tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat
     3181 tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt
     3241 atttgaatca ccaataaaag gaaaaataga aaaaatctat gaaaatagtg tgatgatacg
     3301 tgtcatgaaa tgcgcagtag aagacaatga taccgctcat aatctgcact ggcagttagt
     3361 tgtacgcaaa tcaagtacaa tagaagaata aaaacagata aaatgttgag agcataaaga
     3421 ggttgtgagt ctcccgttta gctctgagtt acaaggaata atgttaaaaa acagcttttc
     3481 atgttttatg aatattgcct tgtgaccgag gtgttggcag gagaatactg tttatttgaa
     3541 aaaagggctg cgacaagact tttgtcacag cctttatttt catgaatagg agttactttt
     3601 ggctactttt agagaagtag cttttaagga gcagataaag tcaaggcttt tatttctata
     3661 aatgaagtag taaaatgaag aacagatttt attacaggaa ggatgccgat aattgtgatc
     3721 attgttgcag gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct tgcccaagat
     3781 ttagaaacaa aaccttttta tgagaacgtg gaagataatg aagtattgcc gctattttat
     3841 tctaatccag aaaagtatac ttttttatta cagattttct ttttgaacaa acgctttttg
     3901 gcaatcaaag atgctttcag ccatgatgac aacgtactag accgctccat ctacgaagat
     3961 agtatgctgt ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga agtaaagcag
     4021 tatgaaggtc ttttagaaac gatgctgaag gagttagaag aaatttcgcc acaaaagaaa
     4081 ccagatctac tggtttatat tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa
     4141 agaggccggg aatatgaaca gctagaacaa gatcctgaac tctattccta ctataaagaa
     4201 ctcaatcgac gatacgaaga gtggtatgaa cagtttgata tatgtcccaa aatagtgatc
     4261 gatggggaca aatatgattt cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa
     4321 atcaagatgc gggcaaagaa aatgacagaa gaggcagatg cccagtcgat ccgctacact
     4381 acaaataacc cgaaagcaaa gggaatcttt acaactaaat aatataaaaa ctaagcaaat
     4441 tgctcactcg cagatatttc tctgtgagca gcatcttgct tagttttttt gattcattga
     4501 gatcaaatag tgaaccgatt cgtatgataa aattgccata aatgaaatgt ctgagtgagg
     4561 gccatgatca aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga
     4621 cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa cgacacttag atagtggaaa
     4681 aatcgatcaa aatctgcttt ttctttagaa atacaataat catataagtt cgttgctacc
     4741 ccttttaaat ttccagttgt aaataaatta gtgtaggcac gcccgttgat tttatcaaaa
     4801 gctacccact ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc gggatgctca
     4861 tggacgggtg tcaaactaac aaagaaaaaa atcactgctt cataatatag aacaaacaag
     4921 cgccagaaat gtttttcttt ttttctaaaa taatcaatta gatactttgt tagaagaatc
     4981 cctaagaaaa agaaaagggt agacaatact tttttaccaa cacttagcca ttctccgtca
     5041 aatgcttgga tgatcgatag aatgatattg ccagtttgag cagaggcaaa agcaccatat
     5101 tggatataag tataactgtc catggctcct ccgataaatg tcagcaaaag tcctattgta
     5161 cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct tttatgaata tttttgtctt
     5221 ccttatctta gcataaacga ttgaaaaaaa aggaaaaatt ttcagaaaac taaaatcata
     5281 tcgcttccca ttttcatttt tagaaaggtc tgttagtata aagaaaaaat agacaacgaa
     5341 actttaaata accaacttga aataaacaaa ttcaaagaag aaagatggga aggaaatcaa
     5401 tcagttgaat gaaaaagaaa ttctccgatt acaaaaagaa ttgaaacgct gggagaacaa
     5461 gtataaaaag cttcaacaag tctttcggct acaagaagaa atcattgcta cctatgaagc
     5521 ggcttatggc gaagcacccg gacttattga ggaagaagta caagtaaaag aaagtgaagg
     5581 aaacagctct ttctttaaaa tgatggagaa acgttcctat aatcgcttca atcaagaaca
     5641 aaaagcagct atcacatatg atatgaagaa acatcttcga atcatagcag gagctgggag
     5701 cggcaaaacg caaacaatct gtgcaaaagc tgtttatctg atgacgcaaa aacaagtaga
     5761 cgaagaacgc atactaatga tcacttttac aaggaacgct gcaaatgaac taaaaaaacg
     5821 agtagataat ttcagccaga gaaaaaccgc tgtccatatc ggaacattcc atagtatctt
     5881 ttttaggata tacaatgaaa tttgtcgaaa atttcctgaa gtagcaatgc aaggaataca
     5941 aggagacttt tcaaaggata ctgcacaaaa agtgaatgct gttttgcaac agctgatacg
     6001 taaatataat ctttatatat ttgatcaata tggagaaaaa acgattgctt ctcggttaga
     6061 ctattggcag aatatgaacc tttcagtaga agaaatggtt cagttagtta aagaaaaata
     6121 tgattccatt gataagaatg cacgacagcc gatatcagaa cgactgtatg gattgctcac
     6181 ggaactccaa gaacaaaaaa gaagccagca attgctagag ttcaatgatg tactccaaaa
     6241 tctgaaaagc gctttggaga atgaggagat ccagcattat atcggccaaa aatatgatta
     6301 tctattcatt gatgaatttc aagatactaa tccacttcaa tgggaaatcg tgaaacggat
     6361 gacaaaggaa aacaggatca agttgattgt tgttggagat gatgatcaga gtatctatgg
     6421 attcagagga tcagagccag catacatcaa gaactttgaa aaagaatatc ctaccaaaac
     6481 tcttttctta ttaactaatt atcgttctcg ggcagctatt gtccaaggag caaatagatt
     6541 gatcagctat aataaaaatg atcggatacc aaaggcgatg attccagcac aaaaagaagc
     6601 aggtgttatg gaagcctatt tgttttctga tactaaagca gaaagtcagt ggctaatcaa
     6661 acaaattcag acatttattc aaaaaaatgg gaaatataag gaatcaatca tattataccg
     6721 atcagcttca caaacgcagc agcttgtcca atctctgctg aaaacgaata ttccttttgt
     6781 actggaagca gatagtccat atgaaggtat ctttggtatc aagtctttcc aacatttcta
     6841 tcaaaaaatt gttcattggc aaacagcact gaatctgcaa aagaaaaatc aggcctacca
     6901 gcaattgctc cggcagctga tggcagactg ctacctgaaa aaaagtgaat gcgatcaata
     6961 cttttctcct aaatatcaaa atatagccgt tgcagattat attttgtcga taagccccaa
     7021 tttaaaatcg aaatctgcag aaatccgaga gtttgaggaa gcgttgcgta aaacagacca
     7081 gcatcaagaa atctattcgc ttgttcaaag ctatcttcat ctgccacgta tagctaagga
     7141 aatcgaccag agtgatcaag aatggatacg agaagaagta aagcagcatg ctactttcag
     7201 aagactccaa gccttatcgc aagaaaccca agcgacagct aaagaattaa aaacccgctt
     7261 gattgcttac agacaaggaa aacttgatgc actatgtatc cagagcattc acaaaagtaa
     7321 aggtcttagt taccgaaatg tctttttgat tggttgtaac gaaggaagtt tgccttataa
     7381 cggagcgaca gaaaagaaag taatcgactt taatgaaata aaagcagaac cagtaacgac
     7441 gatagaagaa gaacgaagac tattttatgt tgcgatgact agagcaagaa atcgtctgta
     7501 tctatgtgta cctcaaatga aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga
     7561 aaccgggagt cgtgtgaaaa aaggaaagtg atagaagaga gggtgtgaca gaagtggtca
     7621 gtttcaagaa agaagaagga atgtacgaaa attgcttctc aaatttttgt gaaatttcag
     7681 cttattttcg aagaagctat ttctggaaca cagtttattc ggaaaaggga ggtgtgacaa
     7741 gaattttgtc acacctccct tatttatttt gaaaatgaga atactattat caaaatagag
     7801 aatatataga aaaattctca ttattcaaac gtaaataatc agttattttg atttttttta
     7861 tattttatta gctaataatt ggtattttaa aagaaattac tgtagaattg gattataatt
     7921 aaaaaggagt gagaaaatga taaaagtata tacttcgcct agctgtactt cctgtagaaa
     7981 agcaagagca tggttgcaag cgaatcaact tgaatttgaa gagaagaata tttttgccga
     8041 accgttaaca gaaagtgaga tcaaaaagat cttggcagcg actgaaggag gagttcaaga
     8101 tattatttcc actcggtcga aaatttacga aaagctgggc atagatttta acgaattaac
     8161 tttaaagcaa atgatcgtct tattcaaaga atatccttca ttattgagac gacctatttt
     8221 gattgatgaa aaaagaatac taatcggatt taatgaagat gagatccggt catttgtccc
     8281 tcgtgaaatt cgatgtgttg ccagaaatct gatctattta caaaacaata acatcttaaa
     8341 ttcataggga gggagccttc gtggaagtga aagtctatgg atcagcgcac tgtgtaacaa
     8401 gtctgaaggc gaaacaatgg ttagaacacc atcaattgcc ttatcaattt gttgacttag
     8461 aagaacgcga tttaagtaca gaagaagcag aagaattatg cagttttgaa gaagtgcaag
     8521 cagaacagct atttgcgact tggtctgagg cttttcacaa cattgcgatt gacctttcct
     8581 gtgtaggaaa aaaacaactg atttttttat gcacacaaca taccaatctc ctcagacgtc
     8641 ctttgattat tatcgatgaa gttctattta ttggatacaa tgagcagttg atggaacagc
     8701 ttatcttaaa taaatagact ttaactgttt taatcaagtc actgagcatt tcatacagtt
     8761 gtaacagtcg aacacttagc atcaagcgtg ttatgtgttc tttttttgac tttatttttc
     8821 tactatagag acatgctcaa tttatgtggt caaaattcaa atctaggtgg ggatatagag
     8881 ttaaaaatat attgacatgt gtaaatttac atgatatatt catttctgtt gttttaagta
     8941 gcaaagcaat aaaatagtat tttaaaaaac atataaaata gttgttgaca tgttagaaat
     9001 gacatgataa gataactgag ttgttaaaaa agaaccactt g
//
LOCUS       DAZAOD010000102         8996 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000102 DAZAOD010000000
VERSION     DAZAOD010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.104"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ACHDPO_002428"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ACHDPO_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFN3370016.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ACHDPO_002429"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ACHDPO_002429"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFN3370017.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="ACHDPO_002430"
     CDS             complement(2169..2906)
                     /locus_tag="ACHDPO_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFN3370018.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="ACHDPO_002431"
     CDS             complement(2997..3524)
                     /locus_tag="ACHDPO_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370019.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="ACHDPO_002432"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="ACHDPO_002432"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFN3370020.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="ACHDPO_002433"
     CDS             complement(4401..4886)
                     /locus_tag="ACHDPO_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFN3370021.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="ACHDPO_002434"
     CDS             complement(5039..5236)
                     /locus_tag="ACHDPO_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370022.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ACHDPO_002435"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ACHDPO_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFN3370023.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ACHDPO_002436"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ACHDPO_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFN3370024.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
BASE COUNT         2539 a         1991 c         1504 g         2962 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctag
//
LOCUS       DAZAOD010000103         8945 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000103 DAZAOD010000000
VERSION     DAZAOD010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.105"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(13..1152)
                     /locus_tag="ACHDPO_002437"
     CDS             complement(13..1152)
                     /locus_tag="ACHDPO_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFN3370025.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1551..2849)
                     /gene="eno"
                     /locus_tag="ACHDPO_002438"
     CDS             complement(1551..2849)
                     /gene="eno"
                     /locus_tag="ACHDPO_002438"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFN3370026.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2965..3720)
                     /gene="tpiA"
                     /locus_tag="ACHDPO_002439"
     CDS             complement(2965..3720)
                     /gene="tpiA"
                     /locus_tag="ACHDPO_002439"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFN3370027.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3824..5014)
                     /gene="pgk"
                     /locus_tag="ACHDPO_002440"
     CDS             complement(3824..5014)
                     /gene="pgk"
                     /locus_tag="ACHDPO_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFN3370028.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5124..6125)
                     /gene="gap"
                     /locus_tag="ACHDPO_002441"
     CDS             complement(5124..6125)
                     /gene="gap"
                     /locus_tag="ACHDPO_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFN3370029.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6166..7257)
                     /locus_tag="ACHDPO_002442"
     CDS             complement(6166..7257)
                     /locus_tag="ACHDPO_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFN3370030.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7406..8740)
                     /gene="rpoN"
                     /locus_tag="ACHDPO_002443"
     CDS             complement(7406..8740)
                     /gene="rpoN"
                     /locus_tag="ACHDPO_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFN3370031.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8800..8871
                     /locus_tag="ACHDPO_002444"
     tRNA            8800..8871
                     /locus_tag="ACHDPO_002444"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8833..8835,aa:Arg,seq:ccg)
BASE COUNT         2321 a         1897 c         1648 g         3079 t
ORIGIN      
        1 attaaaaaaa tcttacgcta agtaggataa aataattcct tgatattttt cgatcatatc
       61 caaataatta tcgatttcaa catactcatc tacttgatga ggcaaagtaa cgacaccagg
      121 cccaaagacg acaaagtcga aggaatggtt agctttcgta aattcggctg catccgttgt
      181 tgctgccgct ccaactaaag gtaatggctg gctgaattgt tgctgaatgc aatgaatcaa
      241 aggagaatct ggatcagctt tgacaggtat tttgttgtaa tcgatcatca attccaaatg
      301 atagtctgtc tcttgattca attcattgac gattgattgc agcaatgcaa tgattttatc
      361 atttgggtat tctggaatcg atcgaatgtt cccttggagc tgcgcatggc ttgggatgct
      421 gttgacttga ttcccgccac tgatcaatgt aacattatgg attgtttttc ctaggacagg
      481 attctcgatt gtttcagcga ggtgattcat ttcagcattt gctttcgtaa tgaattcatt
      541 taggtgattg attgcattat aaccttggtc tggcatagag ctatgcgctt cttttccgtg
      601 cgaggtgact gtatagttga ttgatcccat gtgcgtatac atcaaactgt aattggttgg
      661 ctctccgatg atcaaggcat ctaagtcatc tacatagcct gctttcgtga gctgttcccc
      721 acctagttca cccacttctt ctccgacagt ggctaataat ttgactgttc cgttaaatgg
      781 ttttcctgac tctttcagtt cgatcatggc aatcaccatt gctgccaagc cactcttcat
      841 atctgtagca ccacgtccgt acaaacggtt cccatggatt tctgctgcaa agggtgcata
      901 ggtccaagac gattcatcac cagccgccac gacatccata tgcccagata ggcctaacac
      961 ttttcctgat tggccctttt ggtaacgagc aatcaaatta tctctaccat ctctgtaaga
     1021 aacaatctct cctgttatgt catgctttgc caaaagctta ttcaaatagg ctgctacttc
     1081 accttcgttt ccattcactg atttaattcg gataatctct tgtaaaatcg cgattttttc
     1141 ttcttttttc atctaatcct ctcccttgcc atttcttttt attgtatttg agtgtgctcg
     1201 aattttcaaa taggagcaac caaagtaaaa atgaagaaag agagccactt tatgaaaaat
     1261 atgctgctac ttccctccta ttttatttat acgagaggac ttgcccatag attcctattc
     1321 tactgttcta tccttaaaag ctcttatatg atgctagtta ttgttagctt tcctttttca
     1381 aggatgatct tttcttgtac cattctttgt aaacatcata tacagaagct agttgcaaaa
     1441 aaactctcta cctgctgata tttcagcaag tagagagttc gattacttaa ctaagtgatc
     1501 atactcgact atctttcaat agtcgatcat gtatcttcat tagaaaagaa ttatttgttt
     1561 tttaagttgt agaaagattt caaacctttg tattctgcaa cttcaccaag ttggtcttcg
     1621 atacgtagta attggttgta tttagcaata cggtcagtac gtgatagaga accagttttg
     1681 atttggccag cgtttgttgc aacagcgata tcagagattg ttgaatcttc tgtttcacca
     1741 gaacggtgag atacaactgc tgtgtagcca gcttctttag ccatttcgat agcttcgaaa
     1801 gtttctgtta atgtaccgat ttggttcact ttgataagga ttgagttagc aattcctttt
     1861 tcgatacctt cagataattt ttgagtgttt gttacgaaca agtcgtcacc aactaattga
     1921 actttgtcgc ctaatacgtc agttaatttc ttgaatccgt cccagtcgtt ttcgtctaat
     1981 ccatcttcga ttgagatgat tggatattta gaaactaatt cttcgtagaa tttgatcatt
     2041 tcgtcagttg ttttttcgcc ttcgcctgag tcagctagta cgtaaacacc tttttctttg
     2101 tcgtagaatt ctgaagaagc agcatccata gcaagaacaa cgtctttacc aggtacatag
     2161 ccagcttttt cgattgcttc gatgattact tcaaaacctt cttcgtttga accaaggttt
     2221 ggagcaaatc caccttcgtc accaacagaa gttgctaatc cgcgagcttt caagattgaa
     2281 gctaatgcgt ggaatacttc agcacccata cgtagagctt ctttgaatgt tggagcgcca
     2341 acaggcatga tcatgaattc ttggaagtcg attgagttat cagcatgtga tccgccgttg
     2401 atgatgttca tcattggtgt tggcaatact tttgtgttga atccgcctag gtagtggtat
     2461 aaaggtactt ctaggtagtc agcagctgca cgtgcaacag cgatagaaac acctaaaata
     2521 gcgttcgcac ctaatttacc tttgttagga gttccgtcta aagcgatcat agctttgtcg
     2581 atagccattt ggtcacgaac atcgtagcca atgattgctt cagcaatgat gttgtttacg
     2641 ttgtcgacag ctttagttac acctttaccg ccataacgag ctttgtctcc gtcacgtaat
     2701 tcaactgctt cgtattcacc agttgaagca cctgaaggaa ccattccgcg gccaaaagct
     2761 ccgctttctg tgtatacttc tacttcgatt gttgggttac cacgtgagtc taagatctcg
     2821 cgagcgtaaa catcagtaat aattgacatg ttttgtctct cctttgagtt tgttttttcc
     2881 taagggattt ccctcatata cgattttagt taattttgct cattagtgca aacatttctt
     2941 gcatttttcg caaattttca acaattattt tacagcgtct aacaatgaca agaatgaatc
     3001 tgcttgcaag cttgcgccac cgactaaagc accgtcaaca ttttcttttg ccatgtattc
     3061 agcaatattt tctggtttta cagaaccgcc gtattggata cgaactgctt ctgatacttc
     3121 ttttccataa agtttttcaa ctgtttgacg tacaactcca caaatttcgt cagcgatttg
     3181 tgcgtcagct gatttaccag taccgattgc ccagattggt tcataagcaa taaccatgtt
     3241 tgacacctgt tcagctgaaa gatcagctaa accagctgta atttgtcctt cgatccattc
     3301 agcagttttg cctgcttcat aggtttctaa agattcgccg cagcatagga ttggtgtcat
     3361 accatttgca aagatagctt tcgctttttt attgatgtct tcgtctgttt catggaaata
     3421 ttcacgacgt tctgaatgtc cgatgatcac ataatgaaca cctagatcag caagagctgc
     3481 tggtgaagtt tcaccagtga acgcacctga gttttcccag tagcagtttt gtgctgagat
     3541 ttttagttct gtaccttcag ctgatgtcat taattcttgt aagaataatg caggagatcc
     3601 gatgactgaa tcaactttgt catttgaagg gattttgttt tttactgctt cagcaaattc
     3661 ttttgcttct gatgcagttt tgttcatttt ccagttacct gcgataatag gtttacgcat
     3721 tgaggaacac actccttaat ttattgaaaa atggctaggg agtcatgaaa actcccttca
     3781 ccttttgttc gattactcgt cagaattgag caaacttggt cgtttattta tcgttgattg
     3841 ctgctagtcc tggtaattct ttaccttcaa gcaattccaa gcttgcgccg ccacctgttg
     3901 agatgtgtgt gaatttgtca gcaaatccta attgttctgc tgctgcggct gagtctccgc
     3961 caccgatgat tgttgttgcg ccttctaagt tagcgattgc ttcacaaaca ccgattgtac
     4021 ctttagcaaa gttactcatt tcaaatacac ccataggtcc gttccaaaca actgtttttg
     4081 caccttgtaa tgtatcagca aataatttta ctgatgctgg gccgatgtct aaagccatca
     4141 aaccatcagg aatgtctcct tcgattactt gtgtttcaac atcatttgaa aattctggtg
     4201 cacagacatt gtcgattggc aagacaagtt tgtcgcctgc tttttcgatt aattcttttg
     4261 ctagttccac tttatcagct tctactagag agttaccgat cttgattcct tttgcttcgt
     4321 agaatgtgta agtcattccg ccaccgatca agattttatc tgctttagga atcaagtttt
     4381 cgattacgcc gattttatca gaaacttttg cgccaccaag gattgcaatc attggtcgtt
     4441 ttggttcttc tactgcttca ccgatgaact tgatttcttt ttccatcaag aatccagcaa
     4501 ctgttgggat accagttgaa gcgataccta cgttagaagc atgtgcacgg tgagctgtac
     4561 cgaaagcatc gttaacaaat acatcgccta atgaagccca gtatttacct agttctgtat
     4621 catttttgct ttctttttta ccgtcaatat cttcaaatcg tgtattttcg aatacgacaa
     4681 cgtcgccgtc attcatgttg cggattgctt cttctaattg ttctccgcga gtttcaggta
     4741 cgaatgttac ttctttacct aataattcgc ctagacgttt tgcaactgga gctaaagatt
     4801 ttccttcttt atcttcttct gtttttacac gtccaaggtg agagaaaagg attgcttttc
     4861 cgccttgttc tagaacgtag ttgattgttg gcaatgctgc tttgatacga gtgtcgtcag
     4921 tgatcacgcc gtctttcaaa ggaacgttga agtcaacacg gacaagaact tttttgtctt
     4981 ttaaatcgat atctttcact gttttcttag ccattttatt tcctcctgaa taaacttatt
     5041 atcaaaaaaa gcggaagaag cgcgattgct tccccgcttt taaatgtaca tgtctataat
     5101 ttacacttgt acgtttgtct atcttataag ttagcgaagt attctaaagt acgtactaat
     5161 tgtgcagtgt atgacatttc gttgtcgtac caagcaacag ttttaactaa ttgtttgtcg
     5221 ccaactgtca ttactttagt ttgtgtagca tcaaataatg aaccgtaagt cataccaacg
     5281 atatctgaag aaacgatttc gtctgtgttg tatccgtaag attcgtttga agcttctttc
     5341 attgctgcat tgatttcgtc aacagttact tctttttcaa gaactgttac taattctgtt
     5401 aatgaacctg ttggtacagg aacacgttga gcagctccgt ctaatttacc gttcaattcg
     5461 ggaattacta aaccgatagc tttagcagca cctgttgagt taggaacgat gtttgcagca
     5521 gcagcgcgtg cacggcggaa gtcaccttta ggatgaggtc cgtctagagt catttggtca
     5581 cctgtgtaag cgtggatagt tgtcattaat ccttcaacaa caccaaattt gtcgttcaat
     5641 gttttagcca taggagctaa acagttagta gtacatgaag cacctgagat aactgtttct
     5701 ttaccagtta atgtttcgtg gtttgtgtta taaacgattg ttggaacatc gtttccgcca
     5761 ggagcagaga taacaacgcg tttagcacca gctgttaaat gtttttcagc tgctgattta
     5821 gaagtgaaga aaccagtaca ttctagaacg atatctacgc ctagttcgcc ccatggtaat
     5881 tcttctgggt tgcggttagc taatacttta acttcttttc cgtttacgtt gaatgaacct
     5941 tcatgaactt caactgttcc gttgaaacgt ccttgagttg tgtcgtattt taacaagtgt
     6001 gccaacattt tagcatctgt caagtcgttg attgctacta cttcgattcc atctacatct
     6061 tggatacgac ggaatgctag acgtccaata cgtccaaaac cattaatacc tactttaact
     6121 gtcatttaag atttcctcct tatgaaaatc aaaaaaatat ttattttaaa gggttacccc
     6181 ttttaaaatc tcatttgcag cagcttcatc agtgatgagc cacgtttgtt ttggtgcatt
     6241 tttcatataa gctcgaattg ctttagcttt tgattttccg cccgcgattg ccatgatgat
     6301 cgggactttt tccaaatctt gcaattctat gccgattcta gggaccttat aaacgacttc
     6361 acctttttca ttgaaaaagt agccaaaaga ttccgcaaca gcatttgctt gtttcagcat
     6421 gactaattct ttttcagtca tcttacgacg tgctgccatg tgtaatgcac gcccaatact
     6481 atgaataaca caattcgctt cactaatcaa gtttaagact tcttggatag atggctcatt
     6541 gagtaaagaa ttgtaagttg ccagacttaa ttgttccgga acataaagtg cgcggtggtt
     6601 accgtttgct ttagcagcca ttcttgcact gacagaattt gcctgtacag ttatcgcttc
     6661 accaatcccg cctcttgcag ggacaaacag gttatgccgt ttcttatttt ccagattaga
     6721 caattgttcg gctaccacag ccatagtagt tcctcccatc acagcgatga tattctcgcc
     6781 ttctggaagt agtcggtcta aggcttcgct cagcgcttcg ccgaatgcat cagccacttt
     6841 ggtctgctct tcgctgtttc ctgaaacaac gatacagcgt tggttaccaa aatattctgc
     6901 caactgttgt tcggtttgat gcgtacctaa aagctgatcc atgaagtttt caaggctttg
     6961 ataaacttct tcgcccttag ttgtcagcgt cataccgctt tttgaggtgt cgatcaaatt
     7021 cagatttttc aaaaggtctg tttctgttcg taagactcgt tctgtgatcc ccatactttc
     7081 cgataaactt cgacgcccaa tcggctgcat ccaatagata tttcgtaaaa ttttatagcg
     7141 ttcttgcaac acttcgataa tatctggtgc aacagattca atcattttta tttcatccag
     7201 catagcgatc tccttagttg gacactttac gtccaatgta gacttaaaac gacccatata
     7261 cgataaaaaa agaaattaac tattcgaatt tcacatcaat aaagggaaat ctcaacctca
     7321 cgactgtaag tctaacagtt ttgctctcgt ttttcaacta aaaagactag aaaaagtgaa
     7381 atactttttc tagtcttttg actgattagt tatcataacg ttttcttttt gatgaactcg
     7441 ggattcctaa taaatcacga tattttgcta ctgttcgtct tgagatcgct atctcatctt
     7501 ttttcagcaa ttcaaccaat ttctggtcag acaacggctt gtttttgtct tcttgatcga
     7561 ctaattcctg cagctttttc ttcgctgtat ctgctgaaag gtcttctgtc tgttctgtac
     7621 tattcgtagg aattcgtgta gtgaaaaatt tttttaattc aaatacaccg aagtctgttt
     7681 ccaaatattt cccgttgact gcacgactga ccgtggattc atgcacatct atctcagttg
     7741 caacttcctt taacgtaaga ggcttgattg gacgttcctt gtcgataaag aaagcttttt
     7801 gccgggaaac aatgacttga gcaacccgca aaattgtatc cccacgttgt aggatcgttt
     7861 tcttcaacca ttcgaattcc tgtttccgtt cttttaaata attttcagtt tctttatctg
     7921 cttgttgtga catttgtttg aagtaactct cttgaaagcg tatatttggc tgattttttc
     7981 ggtttgagat aacttgtaca tttttatcgt cgtccactaa tacccggaca tcaggaataa
     8041 tgtacaattc gctgctacgg tcgaaaatcc ggccagggct tggactcaac gtttgtaaat
     8101 agtcgaatat ctgctgaaca gcatgtagat caacagaaaa acgttgtgcg atttctttcc
     8161 attttcgctc caccagttcc tcaaaacatt cttccaacac gatataagct aattccggcg
     8221 cataatcatc tcgttctgtt tgaagcatga gacattcttg caaactacgt gcacctactc
     8281 cagctggttc taattgctga atcagagtca acgcatcgag catttggata ggcgtagctc
     8341 caatctcttt tccggcttct tctaaactaa tcgtcaaaaa tccgttcaaa tcgatgtatt
     8401 ctacaagata aagaacgatt ttcctcaaaa aagtatctcg gtaattcaaa tggacttgtt
     8461 cgatcaatga atcaaataaa gacccttttg tatcaggaat ctgatttagg taatttgtct
     8521 cttctccttc ataagaagat gaagaagctt ttatgtaatc tggctgccat tccggctcaa
     8581 caacttccac caatggattt tccattgctt gattctcaac gaatgccaac agctcctcac
     8641 tgttatattg taaaacttgg atggactgtt gcaactgttg cgtcatggct agtttctgtg
     8701 tctgctgctg tttttgtgaa aaattttgct caaatttcat ttttttgtcc aatccccttg
     8761 taatttttta tctgtttagt tacaattatc ccagtgcttg cgtccttagt gtagtggata
     8821 tcacgtaaga ttccggttct tgagacgggg gttcgattcc ctcaggacgc gttctactgc
     8881 tattttagca taatttacga atagttgctt ctttattttt aagtgaaaac tgtccgccaa
     8941 agaaa
//
LOCUS       DAZAOD010000104         8857 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000104 DAZAOD010000000
VERSION     DAZAOD010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.106"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(159..1469)
                     /locus_tag="ACHDPO_002445"
     CDS             complement(159..1469)
                     /locus_tag="ACHDPO_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFN3370032.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1481..2899)
                     /locus_tag="ACHDPO_002446"
     CDS             complement(1481..2899)
                     /locus_tag="ACHDPO_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3370033.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3139..4707)
                     /locus_tag="ACHDPO_002447"
     CDS             complement(3139..4707)
                     /locus_tag="ACHDPO_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFN3370034.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4711..5121)
                     /locus_tag="ACHDPO_002448"
     CDS             complement(4711..5121)
                     /locus_tag="ACHDPO_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFN3370035.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5118..6041)
                     /locus_tag="ACHDPO_002449"
     CDS             complement(5118..6041)
                     /locus_tag="ACHDPO_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFN3370036.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6038..6916)
                     /locus_tag="ACHDPO_002450"
     CDS             complement(6038..6916)
                     /locus_tag="ACHDPO_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFN3370037.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6903..8240)
                     /locus_tag="ACHDPO_002451"
     CDS             complement(6903..8240)
                     /locus_tag="ACHDPO_002451"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFN3370038.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8243..>8857)
                     /locus_tag="ACHDPO_002452"
     CDS             complement(8243..>8857)
                     /locus_tag="ACHDPO_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFN3370039.1"
                     /translation="QFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRS
                     IGWYLMAAADTYELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGN
                     YLEASGSSMFVYAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNC
                     QVAGLGGADQRDGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
BASE COUNT         2647 a         1918 c         1440 g         2852 t
ORIGIN      
        1 acgacttagt tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat
       61 aaaatgtttc aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc
      121 aagctaaaat attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg
      181 tttgcagctg tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt
      241 actgcttcga ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct
      301 tctataggct tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct
      361 ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt
      421 gattcaggta tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg
      481 ctattttttc tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca
      541 tcaatcatat tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa
      601 gatttcattc gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca
      661 ctaactccag cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat
      721 ctagcaacct cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca
      781 gacttaatag caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt
      841 gttgaagaat caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact
      901 ttttctacta atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga
      961 aaaatcaaat cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt
     1021 ttaatagcat aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg
     1081 cttttttgat cttttcccca atacagctcc caccaatggt ctccttgacc gtcgattatt
     1141 ccttttcctt ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat
     1201 ttcatttcta cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc
     1261 cccttgagga ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct
     1321 ccgactaaat aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg
     1381 attgcttttt gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa
     1441 gcattgataa tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt
     1501 tcaattcttc accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa
     1561 tgattgcgga tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt
     1621 cttgtactaa aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg
     1681 ccagcataaa tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat
     1741 ttactccata tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca
     1801 cgtcagtaat gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa
     1861 ataaaagaat cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca
     1921 tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca
     1981 gctttgtagc aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag
     2041 acattgcttg tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta
     2101 aaatctgatt gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag
     2161 ctaacaaacc ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc
     2221 tttcagtagt caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga
     2281 ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat
     2341 acattaaaat cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc
     2401 ggaacgtgga caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc
     2461 catacgggat attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat
     2521 aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca
     2581 ctaagcaaaa tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta
     2641 actctgagac atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg
     2701 aaatcaagaa taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa
     2761 tcatcaagaa actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt
     2821 agcctatctt atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa
     2881 cagcattttg tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt
     2941 ataactcttt ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga
     3001 cagataaaaa acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta
     3061 cataacaata tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc
     3121 atttattaaa gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc
     3181 agcataactt cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt
     3241 aaaccctcct gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt
     3301 tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt
     3361 cttcttttct gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc
     3421 tatcatacgt aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt
     3481 ggattcattt aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc
     3541 aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc
     3601 gaaggtagat tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt
     3661 atcacaccaa tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc
     3721 ttcaaatgta tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat
     3781 cattatttct tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt
     3841 ccaatacact tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct
     3901 ggtacaaaga tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc
     3961 tgtacattgc aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc
     4021 aagctcgtaa ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc
     4081 tgtaccgcct tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc
     4141 ctccgttttc gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt
     4201 cttctctgca tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg
     4261 ataatcccat agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga
     4321 aggatcaaag ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga
     4381 tgcagtgatc aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt
     4441 gtaaacaaga taaaacaatc catcagcata actgatttgt ggcgcccata tacttccatt
     4501 tgtaggattt ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt
     4561 gactaaattt ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat
     4621 aatgtaatac cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat
     4681 aggatttttc actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata
     4741 taaactgaat gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt
     4801 gccaatcaac aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt
     4861 tcctttagca gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac
     4921 ggcaaacaga ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga
     4981 atgatctaca gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa
     5041 agtaactgct aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa
     5101 tagttcccat tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt
     5161 cttttgatcg atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt
     5221 ttcttgtcat cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct
     5281 tcaaataaga catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca
     5341 ggttctgcag tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta
     5401 gatgctgctg tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga
     5461 aaaacggcat ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca
     5521 taggtctgac gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct
     5581 ttttgcaaat caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag
     5641 ttttttaaag atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct
     5701 cctggacctg ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag
     5761 aaaaaagtag cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca
     5821 aaacgattac cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg
     5881 ctttctatat attcatcata tcttccttct tttactatca agacctttgg atggctatcc
     5941 ggcaggcctg ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct
     6001 atagcattct ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt
     6061 gtttccaaat atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag
     6121 aaaagttttc tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca
     6181 gtacgccttc gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg
     6241 gagcgatttt ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt
     6301 aataaaaccc atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg
     6361 ccgctagatc aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata
     6421 agcctcccat agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct
     6481 ccaaataatc gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg
     6541 ttaataaaaa ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc
     6601 aagcatcaat cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag
     6661 aagctaagta aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt
     6721 gagaatgcag gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg
     6781 ctggtactgt ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt
     6841 gtttttctcg gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa
     6901 aatcattcaa ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat
     6961 tgatttgatt ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt
     7021 ccctcgtgat tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa
     7081 aatccttgtc tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca
     7141 tcttgggcca tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct
     7201 aatccataaa taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg
     7261 atccttctga atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac
     7321 ggttctttcc ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca
     7381 ttatccatga ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta
     7441 gatttcaatc gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta
     7501 cgaatactac cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg
     7561 caatttgtga tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc
     7621 ttgattgcaa tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg
     7681 catgattctg gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag
     7741 ttatcaaacg ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc
     7801 aatttaatat ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga
     7861 ggataagcga gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca
     7921 tctaatgtac cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa
     7981 gcataaactt ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga
     8041 tcgtcagaga atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa
     8101 aataaagctc ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt
     8161 gctgcagcat caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca
     8221 aatgtcaaaa tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg
     8281 caccaacgcc tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac
     8341 catctcgctg atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc
     8401 agccttcttt tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt
     8461 gtggaagcca ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa
     8521 caaacatact actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta
     8581 cttgatacca tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt
     8641 ctagaatttc tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg
     8701 ctgcagccat caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt
     8761 ttggatcagc ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt
     8821 ttggatcgaa tagatgttta taactgattt caaactg
//
LOCUS       DAZAOD010000105         8768 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000105 DAZAOD010000000
VERSION     DAZAOD010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.107"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..292
                     /locus_tag="ACHDPO_002453"
     CDS             <1..292
                     /locus_tag="ACHDPO_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370040.1"
                     /translation="TVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKPVRT
                     RSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(389..823)
                     /locus_tag="ACHDPO_002454"
     CDS             complement(389..823)
                     /locus_tag="ACHDPO_002454"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFN3370041.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1055..1765)
                     /locus_tag="ACHDPO_002455"
     CDS             complement(1055..1765)
                     /locus_tag="ACHDPO_002455"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFN3370042.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1755..2615)
                     /locus_tag="ACHDPO_002456"
     CDS             complement(1755..2615)
                     /locus_tag="ACHDPO_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFN3370043.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2620..3258)
                     /locus_tag="ACHDPO_002457"
     CDS             complement(2620..3258)
                     /locus_tag="ACHDPO_002457"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFN3370044.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3273..3572)
                     /locus_tag="ACHDPO_002458"
     CDS             complement(3273..3572)
                     /locus_tag="ACHDPO_002458"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3370045.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3615..5099)
                     /locus_tag="ACHDPO_002459"
     CDS             complement(3615..5099)
                     /locus_tag="ACHDPO_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFN3370046.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5119..5580)
                     /locus_tag="ACHDPO_002460"
     CDS             complement(5119..5580)
                     /locus_tag="ACHDPO_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3370047.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5598..6665)
                     /gene="ulaG"
                     /locus_tag="ACHDPO_002461"
     CDS             complement(5598..6665)
                     /gene="ulaG"
                     /locus_tag="ACHDPO_002461"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFN3370048.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6883..7653
                     /locus_tag="ACHDPO_002462"
     CDS             6883..7653
                     /locus_tag="ACHDPO_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFN3370049.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7926..8753)
                     /locus_tag="ACHDPO_002463"
     CDS             complement(7926..8753)
                     /locus_tag="ACHDPO_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370050.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2648 a         1852 c         1381 g         2887 t
ORIGIN      
        1 tactgttgaa tttgacagtg aactacttaa gcaatttcca caagaagaac atttcatgta
       61 taaagaagca atttcccaca aagtgacaga gtatttggag cataattttt ttcgtataaa
      121 gccagtgcgt actcgttcgg caaaaggaat atacgagatg aaagtcaaaa ttaataaaaa
      181 aaattatcgc atagcatttg ctttaaaaaa aaatcatgtg ttcatttttt atattagttc
      241 gaatttgcaa aaaattgtat ttgataaaga ggtgagtaaa aaaataaaat agctgagcat
      301 tggaggatag attgagtgat actaagtcta tcctcttgtt tttctaaaga actaagctag
      361 aattttttct tttgtacgtt attatatgtt atttgtcatt accaaaaagc accttttttc
      421 ttctagtatc tatgacataa gaaataccac ccatttcctt tacttgaaca aatcctactg
      481 attcataaaa tttttttgtt ttctcagtat catctgtcaa taattcgatt tggactggtc
      541 cataactagt gatcttctcc aaagcttcat tcaaaagcac tttgcctatt ccttggcgct
      601 gatacctcgg atgaatgagg atatcttgaa taaatgcgat cgtcgcaaaa tcagtgatcc
      661 aacgaacgat tccgataatc ttcccttccc cattacgctt tatcagagat tcagattgtt
      721 caaatgctct agctaacctt gcagtgtctt ttgtgtaatt cgtccaacca acgctcttat
      781 ataattcaga aatctcatcg atcataaggg aatcaatatt catttttttc ttcctttctt
      841 atacaattct ccctctaata atacagttct ttgactattt aatctatcac atataactct
      901 cctgtaaaga ttctctcgat tccttaaaat tcctctttcc ttttagaatg catacttttt
      961 gataaataaa aaggttgtga taaattttct tcacaacctc tgtttctctc tatcaagtgt
     1021 tatcttttaa ttttctaccc ttaccctagc atctctattg cccgtagtat gcatactttc
     1081 catgtttgcg aaaataatgt ttatctagta aatattgcgg gatttcacat atattggggt
     1141 tgatcagctc gttttctttg gccatcagac aaatttcatc taagatcaaa ctgttttcta
     1201 ctgctttcat aggtgaatcc ccccatgtga acggtccatg tccatagaca agtactccag
     1261 ggacttcgtt tggatctaat tttctttcct taaacgtctc gacaatcaca ttccctgtat
     1321 gaacttcgta agcttctctt acttcttctt tcgttaattg gcgtgtacaa ggaaccttac
     1381 cataaaaagc atcagcatga gtcgtgccat aagctggcaa atcgcgtcct gcttgcgccc
     1441 acatgacgga gtgcgtggaa tgagtatgag taatagcagt tatatcttca aaagtttgat
     1501 acaaaacaac atgtgtgggg agatctgaag atggttttaa gctatcttct tctattatat
     1561 ttcccgacaa atctgttacc accatttgat ctgcttgcat gcattcatat ctgacaccgc
     1621 ttggcttaat gacgatgact cctagctcac ggtccacttc actcacattg ccccaagtca
     1681 atttgactaa tccgtatcgc ggcaatgcca gatttgcttc aaggacacgt tgcttcattg
     1741 ctgcaatttt ttcttcacaa gacatcatag ccagcctcct tcaatttaga acttaagtag
     1801 tcttttgcct gctggatttc tcttcgaaag tcttggcttt tttcactcca catttcaatc
     1861 agaaatgttc catcataatc tagacgtttc aaatgtctta ataatccaag aaaatcaaca
     1921 caaccgctac caaaaggaac atcacgaaac tggcctgaat attcttttgt tacagggtaa
     1981 gtatctttta agtggatagc agtgatataa tcgatccctt tctcaagttc tcgagccgga
     2041 ttattttccg gccatgcgga caaattgcct aggtctggat atacttgtag aaaaggtgaa
     2101 tgaatctgtt ctttgatttc taaaaatttt gaaatggagt tcataaatgg atcatccatg
     2161 atttccacgg aaagaatgat gccatattta gaagcttcct ttacgctttc ttttattcct
     2221 tcgataaagt cttctctgga attcattgat ttctcttcat aataaacatc gtatccagct
     2281 atttggatta ctttgacgct tagattatgc gccaaatgga ttgctttttt cattagttgt
     2341 ttcgctgctt ttttcttttc tggatcagca gaaccaaacg gaaatcgccg atgcgcactt
     2401 aaacaaatcg aatggatacg tacaccggag ctgaacatct cttctctcag ctcagctatc
     2461 ttttcttcag accaatctaa tcgtgctaac cgctcatccg tctcatcaat cgacatctcg
     2521 ataaaatcga agtccatttc ttttacaagg gaaaaacgtt ctttccatga aatatctttg
     2581 ggtaacgctt tttcataaat cccaatttga gccatttcct tacccccaga tacgaatgat
     2641 ctcatctttg aagttttgtg cggccttcat cggatcattt gctgctgtaa taccacgacc
     2701 agtgataaag gtatacacat cgatcccttc aaataagtgt aatgtgtgtg gatttaatcc
     2761 accagttaca gaaacattaa agcctagttc aatcagtttt ttgatcttcg ataaatcttt
     2821 ttcaccccaa gtttcaccag ataacagcgc atcacggctt tgatggtaga ttacctgccg
     2881 gataccgatg ttatgccaat ccatggcttg ttcaaaagtc caattgccgt agagttctac
     2941 ttgcaattca cctatttctt tttgtgctgc ctccatagtt ggaatcgttg cacaacaaat
     3001 gactgtcatc cagtctgctc ctgcttttgc aacattactc gccactgttc ctccagcgtc
     3061 tgcacatttc gtatcagcga ctagtttttt atctgggaac atactgcgaa tacagcgaat
     3121 cgctttttgt ccttcctgta agcaaagaat tgtgcccact tcaataatat ctactacatc
     3181 accaactttc ataacatctc ctaatgcatg ttctaagtca ttgtgatcta acgcaatttg
     3241 caaattcggc ctgctcatct tagttccttc ctttacttgt ttttttggta ccactttgtt
     3301 tcagcaaatt tttcactgat ttctttgact gacatcacat ttttgatacc gataactgta
     3361 actccttttt tctctgcctg agtaaacata ttcaaaaaat tgactggcgt aaaaactaca
     3421 tcgtattggc cagctgaact ttttccctct gaaatggcac aatgatggat tttggtaatt
     3481 ggtacgttta gttctttcat tgctttttcc acacttctca tcatcatcaa gcttgttcct
     3541 gatccatttg cacacgatac taaaattctc atcttaatcc ctccattatg agtgttgtct
     3601 aatcagattt tcttttatac tctctgcttt tctgcatatg tgtcatagtc ttctacaatc
     3661 aaaaaataac catcaggatt tttccgatat tgtaactgcg gaatagccaa taaaccaatg
     3721 acaactacgg caattccagc ataacctagg actttcatga ttactgtaaa caatggccaa
     3781 gctgttgccc agtcgaacat cccgatataa ccaccgtatg ttgacatccc aatccatgta
     3841 gcgaataatg ctgaaccgcc tacttgtatg attcctgaaa gaaacgggaa caggcaagcg
     3901 gctttgaatc cacctcggtt attggcataa actgctataa cggcattatc aaagaacaac
     3961 ggaatgaaac cggctatgac gatcgttggt gatttcaata aaatcagtaa accaatcatc
     4021 aaaaactgtc ccaaagcacc aaacaagaac ccaatcgtta ccgcatttgg cgaaccaaag
     4081 ccaaaagtag cagctacgtc aattcctgga acagctcctg gtaaaatcgt gtttgagatt
     4141 ccttggaaag attgagttag ttcatcgacg aatgtccgaa cacctaattg caagatcgcc
     4201 agatataccg caaaatttaa agaagtcgtc ataatgtaga ataagaaact ctgcccttct
     4261 tgcatgaatt gcgcttgaat caaataatct ttgcctagta caatcagaat gatcccaaag
     4321 aaaaatagca tgagtaacga agtagcaacc atattctcat tgaaaatcga caagaatcct
     4381 ggtaatttga tatcttcaat ttttttgtct tgcttgattg atctattttt cttttcatcc
     4441 cgctttttca tccactcagc taattttgca aatataaaga ttccgaacat ttgctgatgt
     4501 gccactgcaa atccggcacc ttctgtcaat tcctgcgtga ttcctactgt taagttagaa
     4561 gctactgtcc aataacaacc taaaatcagt cccataaaaa tcaatgcttg tatcctacct
     4621 agatcaggaa agcaaaacag taaaatccaa aaagcggtag ctgcttgttg aacctgaacg
     4681 tttccggtag tgaaaacgga acgcagtttc gtatatttct gaaaacggac taataagata
     4741 tttaaaacaa atgcaatcag taataaaatc atcacatctc caaaggtacg gccaaatgtc
     4801 tccattaatc cagcatccac agcattttgt ccaaaataag gatctgtaac catggcatcc
     4861 aaattgaacc gttcctttag tccaaccaag attggccgaa aattattgac caaaccacca
     4921 gagccaacag tcaaaataaa gtaaccgacc gttgccttta agaatccagc gatgcattca
     4981 tgaagcgggc gtttcagcaa aatatagcct aataacacga taaaaccaat caggtatgct
     5041 ggctgcgtca agatatttgt tgcaaaatac gtccaaatgc ttaacaaaaa ttcccccatc
     5101 ttttttctcc tctatcaatt aattatattc tgccatcaca acttggtaat catcgatgga
     5161 gttcgtagag atgagacgct caaccaatcc atctgtcatt aataattcgg ataatttttg
     5221 gatattttct agatgttctt ctggatcttt tgctgcgagt gtaaaaaaca aactagccgt
     5281 tttctcctca ttctcccctt cactttcaaa acggattggc tgtttcaact tggtaaatga
     5341 aatagctgtt ccaaaaacac catcactttt ttctgaagaa tgcggcattg ctacttgagg
     5401 tgcgatcaca atataaggac cgtatttttc tacacaatgg atgatctcct ccacatacgt
     5461 ttcatcaata atttccttat cgatcaatac aagacagctt tcggcgatag cttcacgcca
     5521 atccgtgatt tctttatctg ggtaatgaat caattgatgg tcaaaaaagt atttcagcaa
     5581 gaaactcccc ttctttctta taaaaacgac ggaaacggtg tatcattttc aatcgagaag
     5641 acatcttcaa atcctcgata aaaattaaac tcaagatcat ctttgtttgt cggatagatg
     5701 aatttcccgc ctacttgcca gatataaggt ttaaatccat acttcaggcg atcctttttg
     5761 aatttccaaa tttcagtgat ctcttttgga tcagccataa aattagacca aatatcgtag
     5821 tggacaggaa tcactacttt tgcattcaat gactccgcca tgcgcagcat atcaacagaa
     5881 gtaactttgt ctgttatccc tcgtgggttt tcaccatagg cccctaaaca gacatcgatt
     5941 ttgtgttcat taccatgttt ggcaaataaa ttggagtaat gtgaatctcc tgcatgataa
     6001 agattccctc ctgatgtttc gaataaatag tttactgcaa tttgatccat ctcctgaggc
     6061 atttttcctt ttaatacctc ttctggatct tcacaagtga ccaacgctgt ccgatcaaac
     6121 gcttctaaag ctactacatt gatgtctttg attttgactg catcacctgg ctttactgta
     6181 atcgtttttt cttcaggaat tccccatttt tgccacgtgc gaaccacttc ttttggccca
     6241 atgaatgttg cttcaggaca attttgatga actgctgcgg ctgtatggat atctagatga
     6301 tcggaatgga tatgtgtaac gattaaagcg tctacatttt ttatcgcaaa aggatcgatt
     6361 acgaaaggct gagtacgtaa attaggctgc atattttgaa cgccactcat acgcatcatc
     6421 tgatggcctt ttttcatcat gccattccca tgactacgtt ttcccgtccc acaccataga
     6481 tcacataaaa tattcgttcc ttcatgactt ttcagccaaa ttcccgtaca gcccagccac
     6541 cacatagcaa aagttccagg atccactact tctgtttcga tttcttcatt caagtatgtg
     6601 ccccactcag gaaatgtttc tactaaccac ttttcttttg ttacttcatt gacagtttta
     6661 ctcatttgct tgctcccccc atatcgttgt tccaacttac aagtaaatat taatgtgtat
     6721 cagcatccat gaaaaccctt ttatatgacc gtttgttttt tatatgattt tctttcagta
     6781 atcaatgatt gtttcagtat aataaagaca gatatgaatg tttaaatgaa caactagtca
     6841 aataaatcca tggatcaaga tgtccctcag gaggcaaaag tcatgaaaaa ctcacttgtc
     6901 aatattgaaa aacgtcaaaa agaaattttg gaactgcttc agcagactga acaactatca
     6961 actttcgaat tagctgaatc ccttgatgta tctattagta cgatacgaag agatttaaat
     7021 ttattagaag aaaaaaacga gatcatacgc aattacggtt attgttctta taattacaaa
     7081 aaccagactg attttgatca atctggtcct gaaaggatta aacaagcgat tgccagagaa
     7141 gctagtaaat acattaacga ttatgatacg ctgtttatca attctagctc gactgcgttg
     7201 aaaacactgg attttcttca atctaaccat ttgacagtca ttacaaacaa cgtgaaaatc
     7261 aattactctc cgcacaaaga taattgtagt tatattttaa ctggtggaga gatgcgcttt
     7321 ccaaaagaag cactagtggg cgacatcgca ttaaatacga tttcttcagt caatgcagac
     7381 atttgtatca ttggctgtag cggagtcgat gtagtacatg gggtcacaac aaagatatta
     7441 aatgaatcaa cgatcaacga aatgatggtc aacaagacaa tcaaatgtaa gattttagtc
     7501 gctgatcatc gaaaaatcgg actgacatca aagttcaaga ttgctgatat ttcagtcttt
     7561 gattatttga tcactgataa attttgttct gaaaaagtat tagaggagat cagaaatacg
     7621 gggataaaaa ccattcaagt agattcattt taagaaccag gacgtaaata tgtaaatagg
     7681 attatcaaaa aaatgaataa caaatttatc gataaatgaa aaacacgcta cgctcaaatt
     7741 gataaaggaa tcccaagatg tatccatcca atcgatacca tcataatcta ttgcttcttt
     7801 tataaccgtt atatgttgcc taaataggaa tcaaacaata tcgaaaaaag gaggtatgac
     7861 aaaagtcaca cctccttttt tcgaataaac ggtattcaaa tcagaacact gatttcacaa
     7921 ccactttatt tcaggtcgtt ttcaatcacc tttaccgcgt aatcatttcc gttgaaacgc
     7981 gctatttttt ttgcgtccat atatctttct aaataatcat cttctcctaa ttgcttatgg
     8041 caagaagcaa tttcataaag caagtattcc aatgcataag tcgatttatg tttcttatta
     8101 tactcaatac ccttctcaca taattggatt gctttatcat aatcctcgat tttacggtaa
     8161 taggtggcga tatcataata tacaatgcag accatcagat tatcaaaatc agtctcactc
     8221 aatattttaa gtgtacgctc cacataaact ttcgcaaaat ctaattctcc ttttgacaag
     8281 tagatcattg ccacgtttgc agctgcttgt aagtgatgga tatctgtttc ggtcgtttgt
     8341 tccaacactt gattaaaata aaataatgct gcatctggtt ttttcgcata aagatgatca
     8401 agcagtcctt gataaaataa aatttgattt aaaagatcag aattacttac tttttcctga
     8461 tcgatcgttt gtaaaatttt ataagattct tggtattttg atacagaatt caatgattga
     8521 atctcattta tttttttcct gattttgtct tcttctgttt ctactaatat atcggagatc
     8581 tcgacattca gctttttgca aagcgcactt aagatattga tgcctggcga catattcttg
     8641 ttttcgatat tgctgacagt tgcttgttca caaatgcctt ctgctaattg tacttgtgtt
     8701 aacccctttt tctttcggta ttcttttagt aatgctccat ctactttaat caaaacaatt
     8761 tccttccc
//
LOCUS       DAZAOD010000106         8671 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000106 DAZAOD010000000
VERSION     DAZAOD010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.108"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(269..2650)
                     /locus_tag="ACHDPO_002464"
     CDS             complement(269..2650)
                     /locus_tag="ACHDPO_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFN3370051.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2640..3287)
                     /gene="recU"
                     /locus_tag="ACHDPO_002465"
     CDS             complement(2640..3287)
                     /gene="recU"
                     /locus_tag="ACHDPO_002465"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFN3370052.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3351..3890
                     /locus_tag="ACHDPO_002466"
     CDS             3351..3890
                     /locus_tag="ACHDPO_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFN3370053.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            3980..4399
                     /gene="gpsB"
                     /locus_tag="ACHDPO_002467"
     CDS             3980..4399
                     /gene="gpsB"
                     /locus_tag="ACHDPO_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFN3370054.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4421..4788
                     /gene="rnpB"
                     /locus_tag="ACHDPO_002468"
     ncRNA           4421..4788
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACHDPO_002468"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4997..6163
                     /locus_tag="ACHDPO_002469"
     CDS             4997..6163
                     /locus_tag="ACHDPO_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFN3370055.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6209..7705
                     /locus_tag="ACHDPO_002470"
     CDS             6209..7705
                     /locus_tag="ACHDPO_002470"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFN3370056.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7786..8469
                     /locus_tag="ACHDPO_002471"
     CDS             7786..8469
                     /locus_tag="ACHDPO_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFN3370057.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            8478..>8671
                     /locus_tag="ACHDPO_002472"
     CDS             8478..>8671
                     /locus_tag="ACHDPO_002472"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370058.1"
                     /translation="MTEVVSSKIFRIIFRKSYFWNTVYQEVVSLPFSSESQGTISKNS
                     FSCLMNIVTCDSELAGEHRL"
BASE COUNT         2727 a         1571 c         1843 g         2530 t
ORIGIN      
        1 atgggattat taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt
       61 ataaacaagt aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt
      121 ttaagctaaa tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa
      181 tacagcttgg tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac
      241 cacgcttgta gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg
      301 atggtgtatg gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag
      361 gaggagcaga tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg
      421 aagacgctgg ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt
      481 cgctttgact agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag
      541 tctggacata gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg
      601 tatattgatc tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc
      661 agtctgtatt tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg
      721 ctacgtgtga cgattctgaa gtgacaggcg tcattttttt attgtaacct gtccacacgg
      781 aaatcgaata atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa
      841 taccaagttt tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat
      901 ataacccagc gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt
      961 ctgtgatcat ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt
     1021 cttctgttcc gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc
     1081 cattggcgaa agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc
     1141 catcttgttc ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga
     1201 tcccaagatt ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga
     1261 ctgctggaac attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt
     1321 gattatccca gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa
     1381 tagtttttcc agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt
     1441 tcatcgtaga accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt
     1501 cttctgcgat gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa
     1561 gggtggaggc aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga
     1621 tatcatatag tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg
     1681 tgtagacatt cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat
     1741 cgacgatctt agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta
     1801 cattaacagc ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca
     1861 aaacagtatc tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag
     1921 gggcttgagg catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct
     1981 taccaaagta catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt
     2041 tatttacgta gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca
     2101 tccacgcttc ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg
     2161 aaagtttgat caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt
     2221 tagagagggc agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc
     2281 gatcttctac cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt
     2341 tttcacgctt ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg
     2401 aagatacggt agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc
     2461 agaaaagtcc tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga
     2521 tcttgataaa taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat
     2581 tcttcttcac actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt
     2641 catttgccat tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg
     2701 tccaaataag gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc
     2761 aaagataaag gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa
     2821 tgaacactat tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag
     2881 accccatttt gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta
     2941 aagggaaaag atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga
     3001 tagacgccat tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca
     3061 gcacttctct taggatagtc tactttcacg atttggatag gggtaggctt tttatggata
     3121 accgccaacc cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc
     3181 atcccccgat tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga
     3241 gaggcattct tataataagg ttggccattt ggatagcgca ataccatctt taatcacact
     3301 cctaggccac attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt
     3361 caaaagtaat ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg
     3421 atcctaaaat ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag
     3481 aagggctgga atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa
     3541 tagtagcgga attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt
     3601 ctgattttgg taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat
     3661 tagcagatta tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga
     3721 atcacactcg ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat
     3781 tccctggaaa aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct
     3841 acgaaattcg gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt
     3901 gtttgattta tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat
     3961 gaaaactaga ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca
     4021 agaattcaaa acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa
     4081 tatcatcaaa gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga
     4141 tcgattgagt gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt
     4201 gcaacaaaca gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt
     4261 gtcaaatctt gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa
     4321 accagcacaa cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga
     4381 aaaaacacgt caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc
     4441 tgacttgatc aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg
     4501 tgcttagcga aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag
     4561 gcttcggcta tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc
     4621 catccggtgg aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt
     4681 tttgtctgga agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct
     4741 ttgttttttc tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat
     4801 cagggaatta ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag
     4861 ctatttttca atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg
     4921 ttattcggaa tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata
     4981 aataaggaga ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag
     5041 cgggctagaa gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga
     5101 gaacggacgt gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt
     5161 acgtacagca gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga
     5221 attgtttgaa aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt
     5281 tcctgtagct ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat
     5341 cacaaaaaaa gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc
     5401 actgacggaa actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat
     5461 ggtaactctg gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg
     5521 tggagcacca ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa
     5581 agaccgtcca ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt
     5641 aataggccat aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg
     5701 gttcagtcaa gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga
     5761 tattgaatta gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc
     5821 caatgcagaa gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga
     5881 cttcaaaacg gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct
     5941 aggagaagaa gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt
     6001 aaaaacatgg agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca
     6061 aaaagcaacc aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta
     6121 ttggggaact cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca
     6181 ttcaattgga tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa
     6241 agaaatcaat cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat
     6301 gcctgaaaaa gctagtgcat accgaagtga agtagacagc tatctttaca gcatttattt
     6361 ttcaaaaaaa atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga
     6421 agaattgtcg gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga
     6481 acatcgcgta ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg
     6541 acaatggcaa aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca
     6601 aaatattgaa ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta
     6661 tgatgttttg ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt
     6721 tgatcagctt aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga
     6781 acctgaaaca gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt
     6841 gaaagtaatc gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca
     6901 cccatttatg actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac
     6961 agatttcaaa atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca
     7021 agacatcgat gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca
     7081 tgaatcacaa tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa
     7141 gcaatatcct ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa
     7201 attttatcgt tcattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt
     7261 gacttaccct ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg
     7321 ggtagatgtt gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat
     7381 acgaccaaca aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt
     7441 tggttatttt ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt
     7501 gcagcaagaa atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa
     7561 ctggatgtca gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat
     7621 ggatgcaaca catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta
     7681 ttttaatgta tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa
     7741 tctatagatg ttttcagcta tttacttaag aaagaagtgg aacgaatgga taaattacaa
     7801 gtgatcgctg attatagtat ggaccaatta gcgcatgatc aaacaggaca tgggagcgat
     7861 cataccaaaa gagttgtcaa gttagctgaa aaaattttgg agacggaacc gcaggcagac
     7921 cgctttgtga cgcttgcagc agcttaccta catgatacga ttgatgataa agtcgttaaa
     7981 aatgagaacg aggcaaagca acagcttcgt gtattccttc gctctttgcc aatagtagag
     8041 gaacagatct cgatgatttt ttccattatc gaaaatatgt ccttttctaa aaatctctct
     8101 gaagcggccg aactatctct ggaaggtaag atcgttcaag acgctgatcg tatcgaagca
     8161 ttaggagcaa tcggcatttt gcgtactgct tatttcggcg gtggacatgg gcacccgatt
     8221 tttgatcctg aactgtatcc gcaaacattc aaggacaaag aaaattaccg aaaaggcacg
     8281 acagtgatca atcattttta tgaaaaactg ttcttgctgt ctgataaaat gaatactgat
     8341 tacggatatg aagaagccaa acgaagagaa accttcatgc gtgaattctt agaagaattt
     8401 tttctggaat ggtctattga cgatgaaaat tttactccag acaattggat caaaaataac
     8461 aaaaaatgat ggaggttgtg acagaagtgg tcagctccaa gatatttcgg atcattttcc
     8521 gtaaaagtta cttctggaac actgtttacc aagaggtcgt gagcctgccg ttcagctccg
     8581 agtcacaagg aacaatttca aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg
     8641 attcggaatt ggcaggagaa caccgtttat t
//
LOCUS       DAZAOD010000107         8562 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000107 DAZAOD010000000
VERSION     DAZAOD010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8562
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.109"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            16..795
                     /locus_tag="ACHDPO_002473"
     CDS             16..795
                     /locus_tag="ACHDPO_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370059.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            841..1785
                     /locus_tag="ACHDPO_002474"
     CDS             841..1785
                     /locus_tag="ACHDPO_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFN3370060.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1801..2580
                     /locus_tag="ACHDPO_002475"
     CDS             1801..2580
                     /locus_tag="ACHDPO_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFN3370061.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNDKTAPSRRSRSRV"
     gene            2592..3290
                     /locus_tag="ACHDPO_002476"
     CDS             2592..3290
                     /locus_tag="ACHDPO_002476"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFN3370062.1"
                     /translation="MARTQKQKATQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSRDAGYYYGN"
     gene            3318..4082
                     /locus_tag="ACHDPO_002477"
     CDS             3318..4082
                     /locus_tag="ACHDPO_002477"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFN3370063.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLQLGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVAQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4095..5912
                     /locus_tag="ACHDPO_002478"
     CDS             4095..5912
                     /locus_tag="ACHDPO_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFN3370064.1"
                     /translation="MFVLTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASAASSIIILLFINKQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYLSTDSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVIGFVDDDPNKRNTYLSGKKVLGSLKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSMEELASGKISVSKLKTIDVVELLGRDEVELDIESI
                     KDQITNKVILVTGAGGSIGSEICRQIIQFDPAKLLLLGHGENSIYLIDRELRTHHQKC
                     PTEIVPIIADIQDRKKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPVTVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSMQTVMEFVKSLPQDDEQLAKDIVTFANASNK"
     gene            5923..6555
                     /locus_tag="ACHDPO_002479"
     CDS             5923..6555
                     /locus_tag="ACHDPO_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFN3370065.1"
                     /translation="MKAIIVGAGGFGKEIAFLLESFSRYELIGFVDDSLKMQNQELVG
                     KTVLGTIDSLLELEEETAIFLGIASPDIKEKIYQKINKNNKLIFPNLVASSALVGINV
                     QLGIGNILMPYTTYTADVVLGNFNMINIGSTIGHDTQIGNYNSIFPSVNISGHVLLGD
                     KNEIGVGTKIIQNLRIGNMNIIGAGSVVIKNINNKTKNVGVPTKVIERWD"
     gene            6557..7675
                     /locus_tag="ACHDPO_002480"
     CDS             6557..7675
                     /locus_tag="ACHDPO_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFN3370066.1"
                     /translation="MENKRILLASPHMSDEGYEQEYVKEAFDTNWVAPLGMNVNGFEE
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPIIYQGAIPV
                     FVDSDYETWNMNPEHLRTALEKYPNAKAVLVVHLYGLSAELDEITKICKEHNVVLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITVKGINTNHLIDELDKNNIEARPIWKPMHLQPVFDKYEYIGT
                     DVAQTLFEKGICLPSDSKMTDDDLYRVTNTIKRVMQNV"
     gene            7668..8297
                     /locus_tag="ACHDPO_002481"
     CDS             7668..8297
                     /locus_tag="ACHDPO_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFN3370067.1"
                     /translation="MSNRGIYEKFFKRLIDILFSILGLIMLWPLMTFVAILVRIKLGS
                     PVIFKQQRPGKHEKIFLMYKFRTMTDQRDEEGNLLSDDIRLTQFGKILRSTSLDELPE
                     LWNILKGDMSIIGPRPLLVEYLSLYSNEQRKRHFVRPGLTGLAQVSGRNAISWKEKFE
                     KDIEYVENISMMKDIKIFFLTLKKVIVRDGITSVASGTTEKFEGAKIDE"
     gene            8290..>8562
                     /locus_tag="ACHDPO_002482"
     CDS             8290..>8562
                     /locus_tag="ACHDPO_002482"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370068.1"
                     /translation="MSENKKKWLLIHPFDYISRTNILEEILTENSIEYFNVVSDYSHI
                     RKQFLSSKERHMIKNRHVIKTIGYKKNISVMRILSHIWFSIKTLLFI"
BASE COUNT         3030 a         1460 c         1777 g         2295 t
ORIGIN      
        1 cttaggagtg aatctatgga aaagccattc gtcaagtcat tgactgctgt ggcggtaggt
       61 gcaggtgcta ttgcgatctg tttgtttggt taccatatca ataatcagcg gcaacatcag
      121 caacggatca attatgcaga atctgccatc accaatcaaa aagacacctt gacttcttta
      181 tcaaaagaag tagacaagct gtatagtaca aaagaaaaaa attttctaaa ccctgaaata
      241 acagaagaaa caatcacaag tttgtcaaat aagctatcct ctgtcaaact ttcagcagat
      301 gattacgaca tcaaagaatc agaattgcct aaagaagctg ttgcaatcca agatgagaag
      361 aaagcaatcg tgacacagtt agatagtgca gaatcaaaac tgaagatcca gacagctgtc
      421 aacgatttat ttactaaaaa tgtatcaaac tggcagcaag ctgtagacga tgtcgtcatc
      481 aaagaaaagg tgacaagtgc agatgtcgct cgtgtacgtg aaaatatgag cttttttaaa
      541 gatagtcctt ggaaaacggt tgttatgcaa tatctaggat tcgctgatac tcagatcgcg
      601 caagtcacgc aactagatca gttattcgat acgatgttga aggatggtca agtgactgcc
      661 accgctactt acgatcaata tttgacggcg ctcagtcaaa tagagcagat ccggaatgaa
      721 aaaataagcg cagcatacgc aacaaaagca caaactgttg ctcagcaaat gggctatagc
      781 aatataagtt attgacagtt aaaacgttga ttcaagcaag gttagcaaac ggaggaaact
      841 atggcaagac gaagaagaaa atcaagaggg aaaaaaatat ttctgattat tttagcagtt
      901 cttatcgtat tagtattagc aattgtagga gtaggagcaa aattatatct ggatctctca
      961 cattctattg agaaaactta cgaatcagtg gaacgaaccc aaggagaacg aacgaaacca
     1021 gttgatctgg acaaacaaga atctttctct gttctattga tgggcattga tactggagat
     1081 ttaggtcggg tcgatcaagg aagatcagat acgatgatgg ttgccacagt cagtcctgaa
     1141 gacaaacaga caacgatcgt cagcattcct cgagatacgt atgtcgacat cgtaggtcgt
     1201 gacacaaaag acaagatcaa ccacgcttac gcattcggcg gagctgccat ggcgatggat
     1261 accctacaaa aatatgtaga catcccaatc gatcactatg tctctatcaa tatgaaaggg
     1321 ctaaaggaac tcgttgatgc agttggtggt atcgaagtca ataatgacct cactttctca
     1381 caagatggct atgactttcc aatcggtaaa attacattga acggggatca ggcattatct
     1441 tattctcgta tgcgttatga agatccaaat ggtgactatg gtagacaaga gcgtcaaaga
     1501 aagatcgtag aaggtgtagc aaaaaaagta ttgagtttaa acggtgtcag caactatcaa
     1561 tccgttttga atgctctaga gtcgaatatg aaaacagaca tgagctttga tgaaatgaaa
     1621 aaaatcgctt tagattatcg ggaggcattt ggtacgatca agcaagatca gctgcaagga
     1681 gaaggcttca tgcaagataa tatctcctat caaaaagtca gcgatcaaga acttgatcgt
     1741 gtgaaaaaag aattaaaaga tcaaatgaat ctagagaata aataggaaag tggagaaaaa
     1801 atggaagaga caatcagctt gaaagaaatt tttgaaacat tacgcaaaca cttggtaaca
     1861 atcatcatct caatgtttgc tggcttggcc atctcaggaa tcgtaacatt tttcatcttg
     1921 acaccaaaat acagttcaca agcacaattg atcgtgacac tgccacaatc agacacagca
     1981 aatgtcaatg atgtcaatac gaacctgcaa atgatcaata cgtataaaga tatgatcgtc
     2041 agtgatttag tactaaatga agtcaaagat cgtttagaaa cagaagacaa tgtgaaaatg
     2101 actgctggac aaatcaaaga tgcgatctcc gtcaatcagt cacaaaattc acaaatgttc
     2161 tcgatccagg caataagcac gaatgcagtg actgctcaac agatcgctaa tacaacttca
     2221 caagttttcc aagaaaacgc caaagacgtg atgaatgtcg ataaaatctc gattatttca
     2281 ggtgcagttg ccaatacgac acctgtttcg ccaaataata aattgaatct agtgattggc
     2341 ttagtgttag gaatgatggt aggcgtaggt ctggcattct tattcgaatt acttgatcgg
     2401 acagtgaaag atgaaaaata tgtgacggat acattaggat tcccaatctt aggaacagtt
     2461 ccagaaatgt cagcaaaaga attgaacgct ggtatccgta aaaaaggatc agctcctgca
     2521 cgaccaaaag ctacaaacga taaaacagcc ccatcacgca gaagccgctc aagagtctag
     2581 gaggaagaaa aatggcacga acacagaaac aaaaagcaac tcaaactcat gcagtcagtt
     2641 tgatcacatt aacaaaccca tcttcaccaa tcgccgaaca atatcgtacg atccggacga
     2701 atatccagtt tgcctccgca gctggtcagc aaatcaaaac gattgtcgtg acttcatcag
     2761 gtcctggaga aggaaaatcc accactgcag caaacattgc cgttgttttt gccaaatctg
     2821 gtcaacgggt actgctagtc gatgcagact tacgtaagcc cgtcatctat aaaacgttca
     2881 agttgaacaa cgcaagcgga ttaagtactg ttcttagttc atcaggaagt gtagcagatg
     2941 agatccaacg aacaccagtc gacaatttgt cgattctgcc aagtggacct aaaccaccaa
     3001 atccatcaga actactaagt tcgccaagaa tggatcagat tttagcagaa gcaagacaac
     3061 tatttgatgt agtgattttc gacatgccac cagtcgttgc cgtaacagat gcacagatca
     3121 tgtcttcaaa aacggatggc accttattgg tcgtacggga aaatacgtca cgaaaagaat
     3181 cattgactaa agcaaaagaa ctgttagata tggtacaagc gcgagtcctt ggtgttgtat
     3241 acaatggagc agaacacagc agagatgctg gctattacta cgggaattaa gaaataaaaa
     3301 gagaggagac aagagaaatg atcgatctac attgccatat cctgccagga atcgatgacg
     3361 gagcagaaaa catagatgcc agtatcgcca tggctgaaaa agcgattcaa caagggatca
     3421 cacatatttt atgcacaccc catcacaata atggaaaata cagcaatgaa aaatcacaag
     3481 tcatttctct agtcgcttcg ttacaagcag aattagagaa aagacaattg cctttgacgt
     3541 tattggaagg acaagaagta cgtattaccg gaacactgat tgaagacatc caccgagatg
     3601 aaattttatt tacagattta gatgatacat atcttctaat cgaatttccg acactggaag
     3661 tgccgttata tgcagaatgg ctcttttttg agttgttaca actaggaaag acaccagtga
     3721 tcgtccatcc agaacgcaac gcgcattttc gagaagaccc aaatcatttg ctgccattcc
     3781 tagatatggg atgcttggct caactcaccg caccaagtta tgtcggtgta tttggaaaag
     3841 acatccagaa aacagccaaa atgatggtca aacataacct cgtgcaaatg gctgcttccg
     3901 atgcccatgg ggtctctaaa cgtacctttt acttaaaaga atgttatgag caaatcgcca
     3961 aggactttgg taaggaaaaa gtagcacaga tgaaacaagt cgcaaaggac ctgatcaacg
     4021 gggatgagat cagttatcca gtctatgaag aggtaaaaaa gaagaagttt ggtttatttt
     4081 agggggaatg tagggtgttt gtattaacaa gaagaagaaa aattgccaca ttggtatttg
     4141 tggacagctt gttgttgatt gctgcgaata ttgcagcagc taaattcatg aagccgtttg
     4201 tagctatacc aatggacctt attttaatct ctatcggttt gtcgattggt ttttatttat
     4261 tctatggtag tttattcaaa gtttttactc gaatcaatcg ttatacaaat ttaagagaga
     4321 tcattgcgat ttttggttcg ttatctgcaa gtgcggcctc aagtatcatc atattgcttt
     4381 tcataaataa acaatacagt ttacgtttag tgatctttgc atacctactt tcgctattac
     4441 tgatcattgg cagccgattg atctggcgta tctatatcga aacaaaaaat atgaggtatc
     4501 tatcaacaga ttccgctaaa aataccttga tcgttggggc cggcgaaggt ggacgtattt
     4561 tatacaacag ctttcttggt tctaaaacgg ctcaagatat ccatgtcatt ggattcgtgg
     4621 atgatgatcc gaataaaaga aatacctatc tttcaggaaa aaaagtactg gggtcattaa
     4681 aagatatacc ggaattgatc gaaaaatatg acatccaaat ggtaacgatc gctatccctt
     4741 ctttatcaag aaaaaaatta cgaagaatct tcgagttagt cgaatctgct catgtgaaag
     4801 tcaatacgat gccttctatg gaagaacttg cctcagggaa aatcagcgta tcaaaattaa
     4861 aaaccatcga cgtagtggaa ttactgggaa gagatgaggt agagttggat atcgaatcca
     4921 tcaaagacca gatcacaaac aaagtcattc ttgtcaccgg tgcaggagga tcaatcggtt
     4981 cagaaatctg ccggcaaatc atccaatttg accctgcaaa actattactt ttaggtcatg
     5041 gggagaactc gatttacttg attgaccgtg aattacgcac gcatcatcaa aagtgtccta
     5101 cagaaatcgt gccgatcatt gcggatatcc aagatcgcaa gaaaatcaat gagatcatgg
     5161 aacaatacca cccagatatc gtctaccatg cagccgctca taagcatgta ccattgatgg
     5221 aatataaccc aaaagaagca gtcaaaaaca atattttcgg tacaaaaaat gtagcagaag
     5281 cagccaaagc agcgaaagta aaaaacttcg tcatggtctc gacagataaa gccaacaatc
     5341 cgccaaacgt catgggttca acaaaacgaa tcgctgaaat gatcgtgact gggttgaatg
     5401 aagaaggatg tacgaaattc tcagctgtca gatttgggaa tgtccttggt tctcgcggta
     5461 gtgtgattcc agtattccgg gaacaaattg ctcaaggagg gccagtcact gtaacagact
     5521 ttcgtatgac ccgatatttc atgacgattc ctgaagcaag tcgtttagtt attcaatctg
     5581 gggcgttagc aaaaggcggc gaaatcttta ttttagatat gagtgaacca gtgaaaatcg
     5641 tagatctagc aaaaaacatg atccgattga gcggatatag cgaagacgag atcgaaatca
     5701 ttgaaacagg tatccgtcca ggggaaaaac tatatgaaga actattgtta gataaggaaa
     5761 gaaacgatga agcagtttac gagaagatct ttgtgggaaa catcaaaggt tattccatgc
     5821 aaacagtgat ggaatttgtc aagagcctgc cgcaagacga tgaacaattg gctaaagaca
     5881 ttgtcacttt tgcgaatgct tcgaataagt agggggagta aagtgaaagc aattattgta
     5941 ggagctggtg gatttggcaa agagattgct tttctactag aaagtttctc tagatatgaa
     6001 ttgattggtt ttgtcgatga ttcgttaaaa atgcaaaatc aagaattagt gggaaaaact
     6061 gtattgggaa caatagactc gttattagaa ttagaagaag aaactgctat ttttctggga
     6121 atcgcttcgc cagatatcaa agagaaaata tatcaaaaga taaataaaaa taataaattg
     6181 attttcccta atttagttgc atcaagtgca ctagtgggca taaatgttca gttaggaatt
     6241 ggcaatattt tgatgcccta tacgacttac actgctgacg tagttttagg aaatttcaat
     6301 atgatcaata tcggctctac tatcggacat gatactcaaa tcggtaatta taattcaatt
     6361 tttccaagtg taaatatttc aggacatgtt ctattaggag ataaaaatga aattggagta
     6421 ggtactaaaa taatacaaaa tctaagaatt ggaaatatga acattatagg tgcgggaagt
     6481 gtagtaataa aaaatattaa taataagact aaaaatgttg gcgtacctac caaagtcata
     6541 gaaagatggg attaagttgg aaaataaacg aatattatta gcatctcctc atatgagtga
     6601 tgaaggatat gaacaagagt atgtaaaaga agcatttgat acaaattggg tggctccttt
     6661 gggtatgaat gtcaatggtt ttgaagagga attagcagaa tatgtcggtg ctagtcatgc
     6721 agctgcacta tcttctggaa cagcagctat acatctagct ttaaaagcgg ctggggtcgg
     6781 taaagatgat atagtgattt gtcagtcttt gacgttctca gctactgcca atccaatcat
     6841 ctatcaagga gctattccag tatttgttga tagtgattac gaaacttgga atatgaaccc
     6901 tgaacatttg cgaacagcgc tagaaaaata tcctaacgca aaagctgtat tagtagtgca
     6961 tttgtacggt ttatcagctg aactagatga aattactaaa atatgcaaag aacataatgt
     7021 tgttttaatt gaagatgctg cagaatcatt aggaacaaca tataaaggaa aatatactgg
     7081 tacattcggc gactatggaa tttattcttt taatggaaat aagataatca cgacttcagg
     7141 tggcggaatg cttgtgtcta atgacaaaga aaaggtggaa aaagtgaggt tttgggctac
     7201 gcaatctcgt gagaaggcac gccattatca acacaatgaa attggctata attatcgaat
     7261 gagcaatatc gttgcaggta tcggtcgagg acaattgaaa gttttaaatg aaagaattga
     7321 gaaaaaacga tatattcata gtttttataa aaaagaattg tctaaattgt caaatataca
     7381 attcatgcca gaaaataatt ggaatgaacc aaattattgg ttaagtgtca taacagtaaa
     7441 gggaataaat acgaatcatc ttattgatga gttagataaa aataatatag aagcccgccc
     7501 gatatggaaa ccaatgcatt tacagccagt tttcgataag tatgagtata ttggtacaga
     7561 tgttgctcag acattgtttg aaaaaggtat ctgtttacct tcagattcta aaatgaccga
     7621 tgatgatttg tatcgagtaa ctaatacaat taagcgagtg atgcaaaatg tctaatagag
     7681 gtatctacga aaagttcttt aaacgtttga tagatattct tttttcaatt ttaggtttaa
     7741 taatgttatg gccactgatg acgtttgttg caatcctagt tcgaataaag cttggatcgc
     7801 cagtgatctt taaacaacaa cgacctggaa aacatgaaaa gatttttctg atgtataaat
     7861 ttcgaacaat gacagatcaa agagatgaag aaggtaattt attatcagac gatatcagat
     7921 tgactcaatt tggtaaaata ttgcgttcga ctagtcttga tgaactacca gaattatgga
     7981 atattttaaa aggagatatg agtattattg gaccgcgtcc tctgttagtt gagtatcttt
     8041 cactatacag taatgaacaa cgaaaaagac attttgtgcg cccaggttta accggattag
     8101 ctcaagtcag tggtcgtaat gcaattagtt ggaaagaaaa atttgaaaaa gatattgaat
     8161 atgtggagaa catttcaatg atgaaagaca taaaaatatt ttttttaacg ctaaagaaag
     8221 ttattgtccg tgatggaata acatcagtag caagtgggac tactgagaaa tttgagggtg
     8281 cgaagataga tgagtgagaa taaaaaaaag tggctgctta ttcatccttt tgattatatc
     8341 agtcgaacga atatattaga ggaaattctg acggaaaaca gtatcgaata ttttaatgtt
     8401 gtatctgatt actcacatat aagaaaacaa tttctatcca gtaaagaaag gcatatgatt
     8461 aaaaatcgtc atgtgataaa aacgatcgga tataaaaaaa atatatccgt aatgcgaatt
     8521 ttatctcata tatggttttc aataaaaaca ttattattta tt
//
LOCUS       DAZAOD010000108         8041 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000108 DAZAOD010000000
VERSION     DAZAOD010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8041
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.110"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            476..1339
                     /locus_tag="ACHDPO_002483"
     CDS             476..1339
                     /locus_tag="ACHDPO_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFN3370069.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACHDPO_002484"
     CDS             complement(1468..3090)
                     /locus_tag="ACHDPO_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFN3370070.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACHDPO_002485"
     CDS             3339..3860
                     /locus_tag="ACHDPO_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFN3370071.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACHDPO_002486"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACHDPO_002486"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFN3370072.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACHDPO_002487"
     CDS             5941..6759
                     /locus_tag="ACHDPO_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFN3370073.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACHDPO_002488"
     CDS             complement(6862..7059)
                     /locus_tag="ACHDPO_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370074.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACHDPO_002489"
     CDS             7228..7806
                     /locus_tag="ACHDPO_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFN3370075.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACHDPO_002490"
     CDS             7901..8038
                     /locus_tag="ACHDPO_002490"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370076.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2402 a         1465 c         1590 g         2584 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 a
//
LOCUS       DAZAOD010000109         7837 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000109 DAZAOD010000000
VERSION     DAZAOD010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.111"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..813
                     /locus_tag="ACHDPO_002491"
     CDS             <1..813
                     /locus_tag="ACHDPO_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="HFN3370077.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            786..1229
                     /locus_tag="ACHDPO_002492"
     CDS             786..1229
                     /locus_tag="ACHDPO_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370078.1"
                     /translation="MGQYHYKLVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLG
                     TWQTKDHSERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNL
                     LTLRSNKKQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2399..3367
                     /locus_tag="ACHDPO_002493"
     CDS             2399..3367
                     /locus_tag="ACHDPO_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFN3370079.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3384..3908
                     /locus_tag="ACHDPO_002494"
     CDS             3384..3908
                     /locus_tag="ACHDPO_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFN3370080.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKAEKKWWQFWQ"
     gene            complement(4079..5227)
                     /gene="tnpB"
                     /locus_tag="ACHDPO_002495"
     CDS             complement(4079..5227)
                     /gene="tnpB"
                     /locus_tag="ACHDPO_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="HFN3370081.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(5244..5648)
                     /gene="tnpA"
                     /locus_tag="ACHDPO_002496"
     CDS             complement(5244..5648)
                     /gene="tnpA"
                     /locus_tag="ACHDPO_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFN3370082.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            6175..6456
                     /locus_tag="ACHDPO_002497"
     CDS             6175..6456
                     /locus_tag="ACHDPO_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370083.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            6458..6874
                     /locus_tag="ACHDPO_002498"
     CDS             6458..6874
                     /locus_tag="ACHDPO_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370084.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            7496..>7837
                     /locus_tag="ACHDPO_002499"
     CDS             7496..>7837
                     /locus_tag="ACHDPO_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HFN3370085.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2814 a         1358 c         1268 g         2397 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaaac
     1441 actttagtga gttttgtaga aagtaccttt aaaggtactt tcacattacg aacgatacgt
     1501 ccgtaggacg tactgaaagg gtgggattta tgagcgaact aatgcaaaat ttggctagca
     1561 aaaaaagtta aaaaatatat gctaataatc gagcgaaatg aacacttttt caagtgagcg
     1621 aatccgccat gacaaagctg aagcagttta tttcagcttt gtcatggcgt gtgcctagac
     1681 ttttaaaaaa gtcggcacac gagcaaatat ctttatcaag ctctaatttg cgttttaaga
     1741 cgtttgaaac gtctaagtat ataaatatat aagagtaggt ttaagagtgc ttaaatcgaa
     1801 ttttagaggg cattcagaca actttagggt tgttagggct tgccctgacc gcctgtaagg
     1861 cgctttaaga acaagataag ggatttatac taagactgtc ttaaaacgtc tcaaacgaag
     1921 gctcatagct tctcaaagag ttccttatga acatttttag caaaggagcc ggaagcgact
     1981 gcgcagtata atgtgagagc agagcgatca caccttttta agcgactgta gggagtaaga
     2041 ttcccagttg agaaaaatgc gcgaatctgt ttggagaaaa aagaagtggt tttttaggcg
     2101 ggaaattttg tccccctctt ttataatctc tttttaaacc tctttttaaa cctctttacc
     2161 gtcggctata tccttactct cccaagggaa tgacgctttt atctacatcg ttttgtctgt
     2221 ttatctacat cgttttgtct gtttatctac atcgttttgt ctgtttatct acatcgtttt
     2281 gtctgtttgt acattgaatt agtacatcga cgatgttaat ataagatgta gataaacagg
     2341 cattttgtat ttcataacgt gtatctcttg tgcgagtaag aaaggagcta ttttaaatat
     2401 gtctaatgaa atcgtaaagt atcatcatga attaaataca attccgttgc gaaaatttac
     2461 accagtcgaa atgaatttgt tcttttctat cgtatcaaga atgcgtgatg taggtgataa
     2521 aaaagtacaa tttacattcg agcaattaaa agatttaagc aattataaag caactgcaaa
     2581 tgttcgattc atagatgatt tagaaacaac gtatgacaaa ttaatggatt tacgttttgg
     2641 tagaagaagt gctgacggtt tgcaacgtga acgttttgtt ttatttaatc aatttaaaat
     2701 cgacggaaaa tctgatattc cttttgctga aatacaagtt catgaaaaag ccttaccctt
     2761 acttaataat cttgaagaat gggtgcgcta ttctctccaa caattcaatg aattagaaag
     2821 cagttattca aaaacaatgt ttcgattact aaaacaatac agaaccaaag gtttcgctta
     2881 tttttcaaaa gaagactttc atgaattact tgatattcct aaaagttaca accaaggtac
     2941 gattgatcaa cgtgtgttca atccaatacg acaagaacta accgcaatct ttaaaggttt
     3001 aacaatcaaa aagaaatacg gaaaaggacg gggaaagcct gtcattggct atcaatttac
     3061 atttaaacct gagataaaaa aatcagacga ctttaacaaa catgccccaa caaaagaaga
     3121 acaaaacaaa gcattagaac tagctaacca acaagttcaa tctgaaaaag cacctacttc
     3181 attacaagaa aaaatcaaag aacaaaagcg aaaattggaa cttttacaac agttagaaaa
     3241 gttagaaaga gaacaaaata cccaaaataa agaaaataat gcacaaaaat cagagataaa
     3301 ttccgatatt ccttcagaac taaaaaaaga cttattagac aatcttcaaa acttattcaa
     3361 agattgaggg gtttttagat tttatgacag aaaaaacaat caaagaactt gctgaagaat
     3421 taggagttag taaaacagca attaacaaaa aagtttctga cgaaaatcga aaactttggt
     3481 tttcgaaaat cggaaacaag tttgtgatta atgaaaccgg acaaaaggct ataaaatcaa
     3541 tgttttttaa cgaaaacgaa aactcaaatc aacaactagt tggcgaaaaa acgaaaaccg
     3601 aaaaccacaa aaacgccaac caagttcccg aattagaagt cctttctctc ctagaacaac
     3661 agttaaatca aaaagatatg caactacaag aaaaagacga gcaaataaaa caaatgcaaa
     3721 aattactcga ccaccaacaa caactcaccc tgcaagccaa ccaacaaatc gagaaactgc
     3781 aggaacaact acagttgact tatacggaag aatcttcgga aaataaatca acgactcttt
     3841 ctgaagaaac agaatcgata gaaaaacaat caaaggcgga gaaaaaatgg tggcaattct
     3901 ggcaataaaa ccagcaatgt gaactactca ccacttagct aaacctgacg gttcttaacg
     3961 cttgaagtgg gagcttcttg ggaatagagc atacttgata gcgtatttct ttactaacag
     4021 cggtgtctct tatttaccaa gctatccccg tagttcctac ggttcttgat gattggatct
     4081 aagccaatcc catagaatgt agtcttagac cttcggtcag aatattgata ctagcattga
     4141 tatcacgatc atgatgagta tgacaaacag gacaagtcca ttctcgaatt tcaagagatt
     4201 tcttgccatc tttatgtccg cactctgaac aaatctgact agacggaaac catttatcta
     4261 ctttgatgat ttttcgtcca taccagtcag ccttgtattg taatttagtc acaaactttg
     4321 accaagaaac atcagaaata cttttagcta atttatgatt tcgcaacata ccttttgtgt
     4381 ttaagtcttc aatacagata atatcgtgat ttttgatcat ttctgtactc aacttattca
     4441 gaaaatcagt acgttgattc attacttttt catgcaatct agctactttg cgtttttgtt
     4501 tttgataatt tttagcttca aatagattgg tacctttatt tttagccaat aaagcacgcc
     4561 tagacaattt gcgttgttca cgctttagtt tcttttccat tttggacgtg aatttattat
     4621 tatcaatttt ttgtccatca gaaagaatcg caaagtccat aatacctaag tcaataccaa
     4681 ttgtggaatt agttttaggt aattcgataa tttcttcttt acacaacaaa gaaatatagt
     4741 atttaccgct agaatgacgt gatattgtag cggatttgat aatccctttt ggttgtctat
     4801 gaagcttaat tcttactaat gacttcaatt taggaacttt gatgaattta ctatcaatca
     4861 aagcaactgt accattttga ttattcgttg tataactctg aacaggattt ttcttacttt
     4921 tgaaacgtgg aaatccaacg gatttatccc gaaaaaaatt cttgtatgct ttatctaaat
     4981 taagttgggc attggctaaa gcaaggctat caatttcttt caaaaacgga aattctttct
     5041 tgtatttagc tggtgtcgga aaagtcattt ttttagaaga atcattttta acttcttcat
     5101 acgccttttt tcggtcatca agcattagat tgtagacctt acggacacaa ccaaaagatt
     5161 tggcaaagaa gatttcttgt tcctctgttg gatagattct gaatttgtat gcttttagtt
     5221 gttccataaa gttcacctac tttctattta tgattgtttc cttgattttg gatatacttc
     5281 ttaatcacat caattggtgc gccaccagtt gtcagaagac aaaaactttt agaccagaac
     5341 atttctttcc aaagaaattg tttgactctt ggaaagtcac gttttatcaa tcttgagctg
     5401 gcacttttat aggcattgat gaattttgtc aattctgttt taggttgagc tttgaacata
     5461 atatgaacgt ggtctttatc atgattccac tccactaaag taatgtgata cgattctgaa
     5521 attctttcaa aagtagtttt ggcataatca gatatttcat catcaatcac ttgtctacga
     5581 tatttcgtta ctaaaacaag gtggtaataa agaagaaata ctgaatgatt atttgtatct
     5641 aattccatgt tatatcaact catttcttgt atagactgat tgtaacatgg aacaaaataa
     5701 aaaggcaata cgccttagtt gtcggtcttc gagttaccaa cggtaaccct cataccgaac
     5761 ggcattcatc acccacctat agaggatggg cgacttctgc ctaattctgt taaattaata
     5821 aaaattgctg gttttattct tctttttgct tttgcgagca gagcaacatg gacccatgtt
     5881 gcgatatttt ggtggcgccc caatccccgt tttttcgttg aatcttactc ggactgcact
     5941 cgttttacag ctgatttttc tgaattttga aagagcataa ggaaacgtgg tatcactttc
     6001 ttacgaaagg tgctagatag gctgtgccta tcacgtttct cagaaaaaaa tttgctatca
     6061 cttttttgcc attgtggcta ggctatgtat agtgttttgg cgaaaaatag ctatacaaat
     6121 actatatttg tatggtatac ataaattata cgctgatacg aaaggaaaat ttccatggac
     6181 attttagttc gaaatatcaa tcccaaaatt attgcaagaa tagataaacg ttgtcaggaa
     6241 ctcacaacca aaacgggcaa aaaatggagt cgaaataaat atctaaaagt tctaatcgaa
     6301 agtgattttg accgtcaact tatgaattac aaaaaagatc aattcgattt attactcgaa
     6361 aaatttattg ccattcaaac agaaaatacg aacatactga atgactatgt tcacacaaac
     6421 aaccaactca ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa
     6481 acacgtaacc ctttatccca gtcacgttga cgttttagat tccatcatcg aaaaaaatcc
     6541 agacgtcaac aattattcag aagccattcg ttttttatgt atgagttatg aacctgatac
     6601 caatacaacc acaaccagta accaagcaaa actcaatgcc atgggaaaag aaatttctat
     6661 catgacagaa atcatggcag aatttgctga tttatatcta aaagatactg gtgttcttat
     6721 cggtacaaat tctaaagtgt atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc
     6781 ttcccgacga aatcaaccca aaaatcgtca aaaagaaacc aatcaaacct ttacttctgg
     6841 aaattttgac ccaacaaact ttctaaaaag ataaaaaaag aaaccgatcc ctaaaaaaat
     6901 tcctcgattt ctttttaggg atcagtcttc cagcaagatt tgcaagttgg taccaacttg
     6961 cgaaaaaaaa gaaaaatccg cttatgcaac ttcttctttt tgtattttga ggcgctaccc
     7021 caatccccaa gtatcggtta tttaatagcg cggaaatcca aagaatagga cgtaccctga
     7081 aacaaaaaaa gactgctctc acgagcagcc caaaatgaga ttatcctatt catcaacata
     7141 aaaatattac aaagtgaaga actagagaaa gacaaaaaaa gcatatcaaa tcctctcaaa
     7201 aataacaagt ctttaaaaaa tgacagataa aaatgcacaa agaactaaaa aagagaaatc
     7261 gcgtaaaatc aagcattaga agctagtaac tagctagacc aattaaaaat cacaaagtga
     7321 gcgtctctat ccattggtag aggggctact tggcatagtc gacattatgt taactaacgc
     7381 tataaataac gattatgttc ccaaaacaat attttatgaa ctataacaaa aatttgttat
     7441 cgcatattgt atattttaat tataggtgta taccacttaa atttaacaca aaggcgtgat
     7501 tattttgaaa cccaaaaaga aaatttatct aggtctcctc ttttccttga tgattggaat
     7561 ttttagtata ggaattacaa atacctatgc ttcagaaaat tctaatttca atatcaactc
     7621 ccaaccaatt gaagaacaag caattaattt tgcgaaaact gattttgaac actccataac
     7681 ttcaattctt ttaatggaaa ataacaccga aactgatatt aactatactc ttggttcgcc
     7741 atttaaaatg ctcgatggag aaaatacggc aaatagttct attttctttc cagtattttc
     7801 agacgctgat aatacgatta aatatattta taccgtc
//
LOCUS       DAZAOD010000110         7812 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000110 DAZAOD010000000
VERSION     DAZAOD010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.112"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(32..1384)
                     /gene="celB"
                     /locus_tag="ACHDPO_002500"
     CDS             complement(32..1384)
                     /gene="celB"
                     /locus_tag="ACHDPO_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFN3370086.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(1384..1902)
                     /locus_tag="ACHDPO_002501"
     CDS             complement(1384..1902)
                     /locus_tag="ACHDPO_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370087.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(1918..2244)
                     /locus_tag="ACHDPO_002502"
     CDS             complement(1918..2244)
                     /locus_tag="ACHDPO_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFN3370088.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(2257..4236)
                     /locus_tag="ACHDPO_002503"
     CDS             complement(2257..4236)
                     /locus_tag="ACHDPO_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFN3370089.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(4257..4571)
                     /locus_tag="ACHDPO_002504"
     CDS             complement(4257..4571)
                     /locus_tag="ACHDPO_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFN3370090.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4739..5032
                     /locus_tag="ACHDPO_002505"
     CDS             4739..5032
                     /locus_tag="ACHDPO_002505"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFN3370091.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(5110..6222)
                     /locus_tag="ACHDPO_002506"
     CDS             complement(5110..6222)
                     /locus_tag="ACHDPO_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFN3370092.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            6375..7223
                     /locus_tag="ACHDPO_002507"
                     /pseudo
     CDS             6375..7223
                     /locus_tag="ACHDPO_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7576..>7812)
                     /locus_tag="ACHDPO_002508"
     CDS             complement(7576..>7812)
                     /locus_tag="ACHDPO_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFN3370093.1"
                     /translation="DATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKH
                     LPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT         2495 a         1554 c         1262 g         2501 t
ORIGIN      
        1 ttttttgtca cagttccttt tttcttagaa atcattttaa cttttcacta gctaattctg
       61 ctgccttttc tctttcttca tttaataatt tattatcata gaatttgata aatgggaacc
      121 agataatgaa tgcgatgatt gcacaaatga ctgctaacac agcagctttc caatcaccac
      181 cactaccaac aaatgctccg atcccgactg gtgaaggcca cggcatctgt gcaagcatcg
      241 gtttgacgat ttccagccga atggcaaaat aagcgagtgt agcagaagcc atcggagcta
      301 agaaaaacgg aaccgctaaa tagggattgt agacgattgg catcccgaaa atgattggtt
      361 cattgatatt gaataatcct ggtacaagtg aggcttttcc taacactttc agctgatcag
      421 atttcgcgag gaatgcaata aagatgatca atcctaaagt cgcacctgat ccaccaacgg
      481 ttacataaga attgttgaat tctcctgcca acggataatt tgcgccttgt gcgttagctg
      541 ccatattagc taatacgatc ggggtcaaga aagaagtgat gatattcgct ccatggatcc
      601 ctacgatcca caatgcatgg atcaagaaat aaatcaccat gacaccaagc catgtattcg
      661 tcaactgcgt aacaaaccca aatgggatag caatcatttt gaagatatcc gttcctagtg
      721 caactaataa tccattgatg atcatcacca caaacgcaat gacaaatgtt gggatcagag
      781 cagtgaaaga acgagaaact cctggcggaa caacatctgg catttttatg acccaatttc
      841 tcttgacaca catacaatac aattcgaccg caataatcga cataataata gctgtaaaga
      901 ttcctgaagt tcctaaacgt tcgacaaaag agcccatcct aataccattt actacagttt
      961 ctgtctcatt gatagaagca atcaagctga ttttaccatc agtcatgatc aattcaggga
     1021 tacacataaa gaatgcaaaa acagatagta atgcccccgt gagcggatta acatttaatt
     1081 tttgttcatc tcgttcaatt gacgttaatt cataagcaaa cacaatggca aagtaaatag
     1141 ataaaatccc catcgtcatt gtattgacga tcatgtacaa gtcactaact ttgaaaaaag
     1201 ttgcattaaa aaatccttct aaaaatggga acggtaatgg caaaatattt aaaaccaaaa
     1261 acatcgagcc tacaatcgtg aaaggaatag aagccatccc cgctgccatg acagcccgaa
     1321 cgattttaag ttgcgcaatt ttccccatag gtcccatcag gtatttctgc aaaaaatcaa
     1381 acattagtta ttctcctttc ctaaatataa cgctttttca tattgtttaa tacggatata
     1441 ctgttggtct tggttgagtg aaattttctt taaacgatac tgtataaatg cactggcaaa
     1501 aataccgctt acaacaagaa tgaaaacaaa taactgtcct ccattgttat ttgccataaa
     1561 aggatacaag aatgtaaatc ctgaggtaaa caacactgga atcactaata aattaaagac
     1621 actctggaac aaaaaatacc actttgtcca tggaacgttc gtttggtgtt ttcgataaag
     1681 ctttacttgt tctcctactg caggcaaaat agctaaaatc agaatcatcg gtaaactact
     1741 tcctaaactt ttagctgata gaagcagaat catccattgc atgttcatga aaaagaaaaa
     1801 ggcagtcagg taacgtacga ttagataacg attgaaatac atgtttttca aactaagttg
     1861 ctttttttct aattcgattt tcctttttac tgtatcctgc acaatgatcc ttcctttcta
     1921 tttatttttt tgatacaaat aattcatttc ctgtgcaact tccaataatg tcatcgtcgt
     1981 catcagatga tcttgtgcat ggaccatgat aatttccatt tctatttttg tcccgctggc
     2041 atattctttc agaagttgag tttgtgactg atgcgcatga agaatctctt catttgcttg
     2101 tcgcaacttc tcttctactt cttcaaacat ctctttacgc atcgagcgaa atgcttcatg
     2161 tatcagtgtc cgtgcatttc cgctatggaa aatgatatca aaagaagtca cttgtagtgt
     2221 ttcactgttt attttttcag ccatctgttt tcctccttat tcgatcagtt tgataaattt
     2281 actgctgaaa ttctcaaaaa taggttcagc taagatttcc tgctgtactt ttagctggtc
     2341 aactaaccta acgattgctt tagtcacgac cgtaattcct tcattttcga cataagaagg
     2401 cgaaactaaa aaaacaaaat gaatttcttg atattgatcc cactgcatcc cagaaggaat
     2461 caatgcaacg gctacctttg tttcgattcc aactggaaca gcgggatgtg ggactgccac
     2521 tgtatcactg aatatgattt gtcccatatt ttcacgttgc tggatctgct ttcgcatttc
     2581 tcttatatat ccttcttctt catttatgct cagcttttgc agcaaatcat gaagaatttc
     2641 ttcctttttc ggttcgtacg tataagtctt gaaaaatttt tcagacaact gttcggtgta
     2701 aatctgcttt ttttgctgta gagaaaatgc tggtatcggt ctatctgagg aatgataggg
     2761 tatagattct ccaactacct ttcgtatttt acgaacatca tcttcattca aaaaaatact
     2821 gacatgtaaa actggaattt tgaaaaacat tgtcgaaaga tcaatagaag aaataatcag
     2881 gtcgattcct tttaaagttg tttcattgat ctcataatag ccttttacac ttaccactgt
     2941 aatattttta ccgaattcac tgactacgcg attctttaat agttgggcac tgccgtaacc
     3001 cgttgcacag ataatcaatg catgtagttt atgcgcagct ctttcttttt ccaatgccgc
     3061 catgagatgc aaagccaaat aggcccattc atcttcattg atggtatagt ttttcaaagc
     3121 cggcatgttg ctgaaatgcc tttttactgc gtcaaagact ttgggatttt ctttctttat
     3181 ctcctcagtc aatgggttct caatgcgaat acctcggctc aatcgaatca tcatcggtga
     3241 caaatgatcg agtagtccat tgaaaagctg gagatcctct actaatgaaa aatgaaattc
     3301 ctgagacaat cttttcagaa ctttcgctaa ttcctttgat agttcctgat cattttgatt
     3361 ttctttgtga ttcgacttag ccatgagatg taatgtcaaa taagcaattt cttcttcggg
     3421 aaacgataca cctgcgatta cctcaatacg ttgaacgatc cgctgcgcca cttgatactc
     3481 tactcgctta gaaacttctt gttcgatgcc taattccttg atttcaaacc cttctcggag
     3541 ccgtttgatc cccaaagcca agtgtaaagt cagattctgt atgataaaat ccgaaacttt
     3601 taacttagct tctcttgttt catcgagaat gataatgact agctcttcaa aactgatgtc
     3661 tgggaaaaaa cggctttgcc ctaaatattc tttcaatgaa tttccataat ggtttccaaa
     3721 aaaagtatcc atgataaaat gccgtcgatt tctttcttcc ccttcgatcc atgtcccttg
     3781 accatgctta gaaacgattt ttagtgaata tggaatcaat cgctccttga tttcttgcat
     3841 gtcctttgtc aaactggaac gactgatata aagctcttct gccaaatcat ccataaaaag
     3901 aatggcatct tccaaaagca attggttcaa tatatacttt tgtcgatctt cggactcata
     3961 aaatccttgc ggttctctag catatccagg tactatttct tgccgactca aaaacaagtc
     4021 aaatgtcagt ctttgtaaaa tatgcagttg gtagccataa cctggtttag caatgatctt
     4081 acctccgttt ttttctacta actctttgat ccgctgcaag taattacgga ttgtccgatc
     4141 agataataac aattcagaag ctaaacgttg actggtgaca tactccttct tgtgatcaat
     4201 caaatatctc aacagcaatt tttccttctg tttcattatc atccactcct attccatcat
     4261 atgttctctt cgatcacctc tgctaacttc tggatgcctg tagggattgg gacatacgct
     4321 tggaaaggga tactaacaac aggctttcca acagattctc ctaatttttt gaatttatcc
     4381 aaaaacatcg tcgtttgcgg gctgatcaga aataaatcaa aatcactatt cttaatcata
     4441 ttatcgcctt ctgtagctga aactgcatct acgagtacct cttctctttt ttgcttaaag
     4501 aaatccgttg tctttgaggc catcatcgag gatgacattc ctgccgcaca aataatcaat
     4561 gcttttttca taaatcaatc actcctttta tttttataaa ccaagcatat cttgtaagcg
     4621 ttttctattc aaaatatata tttccgtagc attgcggaaa aaatgtgtat catatcttga
     4681 ataataattt ctggcaccgt gatatactag tgatagaatt ttttcaggag gggatttagt
     4741 gagtatcaca gtgaatattt tgtatacaag tacaaatgga caagccagaa aatttgcaga
     4801 agaaatggtc gaaagaaaca ttgtcaaagc gattcgtgca gaagaaggaa acgagaaata
     4861 tgactattac tttccactag aagatccaga atctctttta ctgatcgacc gttggaaaga
     4921 tgaagaagca atcgaaaagc atcacaaatc cgaaatgatg gctcaaataa acgaactccg
     4981 taaaaagtat aaattaaaaa tgaaagtcga acgtttcact gatttaccgt aaaaagatac
     5041 acatggaatg atagcaattt atcatccatg tgtatcttca ctttttcctt attttttatt
     5101 cgatctcatc taatgattca aaccgtgttt ttctcttatt tttcggataa gtatttcagt
     5161 caccccaata tacatgattc ctaaacatac cccaaggata ttctcaaaaa tgcggatcgt
     5221 tactgctcct ggaaccccga ataaactggc agtgattgcc aaagcaccaa aagaattaaa
     5281 aactgtttta tatctatagg tagaacaaac acctaaagct agaccaccta atataccgac
     5341 ccagttaaaa ggaataaatt ggctgatacc aataaataaa acacatccaa tcaatgagcc
     5401 aatgattcgg tctactgctc gttctttgaa accaatcgac atcaatccat agctagatac
     5461 aatagaagaa aatgcaaacc ctgcccacat caatcgctga aaagggacat actctcctgc
     5521 aacgatcaaa agactaatgc caaatgcata gatgagcatc caaatttttt cctgcgaata
     5581 catgcctttc aaaaaaatct ctttaaacaa gcttttgtct ttgttctttt ctcgatgttt
     5641 tctgtaaagg agaactgaaa accaacaaaa aaacaaaaat aataagctac ttgtttgtgt
     5701 aaagaaattc ttgttcaacg aatctttagg taacgaataa acaataaaga gatatgaaaa
     5761 gccgtacaaa gaagcattcc ccattttggg atcactagcg gttgccatta atatgctgct
     5821 tagtaaaata aaatgaatca acatgcccat aactgaccat ttgatcagct ggacatacgg
     5881 tgctactaat agtgagaaca tgacgattgc taaacctatg atcgaatggg aaatcttata
     5941 accaaagtca acaaaacgaa tactcatcaa catacagaat aaaaccacag cgtatggttt
     6001 atgcttcgat tcaaataatg ttgtaattat aatgataaaa caaatggcaa acaatacgat
     6061 gaataatgat cgtaaaaaca atgaacaaat atacatgcac ttttcttttt tagaagctgc
     6121 ttctcgtatt ttttgtttta aaataaacgg atctagttgt agagactgat aaaaatccac
     6181 ctgttgtcgt cctttctttt tacttttatt ttttacagtc atctatgaca ggttgtaaat
     6241 actatggaac atcatatggc gttgtcattt tcttgtcaac tatttttcct attcatgttt
     6301 ttataaaaaa acatatcgtt ttcttgtatg attaaatcac cacaaaataa acaactgaga
     6361 gaacgatatg ctttatgaat ggttctatca aaaaaattct gagatcaata gacaaaaatt
     6421 tgatgattac agaggtctct tacgaaacct tacagaagaa aaaaacattg atcgttgctg
     6481 cagttctctt ccctgctcca tgtgtctgta gaaattgtgg ttctgctgtg gtagatggaa
     6541 ataggaaatt aatggtggtg aaaaacaaga agaaggaaac cattgtccac tttgaataat
     6601 ataatcatat gccaatggtt atacgcctaa aaaagcagcg ctatacctgt aaaaactgtc
     6661 gaagccattg gaacgctcaa agttatttta tccgtccaag gcactcgatt tcaaatcatg
     6721 tcagacataa aatcacttct ttactgactg aaaaagtgtc gttatttttt atttcgaaaa
     6781 gttgttaggt atctttgaca accgttattc gcacattgaa agagttgaga agctatttac
     6841 caaagtcttc caaaagaatt ctgtcttgag tgttgagggt tgtgaatttc gttctcacgt
     6901 ttccgttgag gataaactga gttttatttc cgcggatggc gagacagaaa aattaatcga
     6961 gaaaatttac ctacacaaaa aattcctcga ttaacaaact atttccttag ctgcactaat
     7021 cctaaagaaa tagaattctt agttacagac atgaacgcca cctactttca gctcaccaaa
     7081 catgttctac caaatgcgaa attggtgatt gatcgattac ttggtttttc cacgcctttc
     7141 aaggaggcgt aacctttatt cacgagttgg ttgaagcttt ccgagacaaa agacccgact
     7201 tgtttttctc cttattgaca aagagccatt aaaactagag aaaaaattac aactgatcgc
     7261 tgattatttg tagaaagaaa atcaaagtat tacccaataa acttgagtca ttaggcaaaa
     7321 aacactgcga aactcaagaa tgattttcgc agtgtttttg tatatttttt attaactagt
     7381 attactacaa aggtttattt ttcacttctc aacgcagcac aaaattgtct ttacttattt
     7441 actggttggg ttcaaccttc tctactccga tactaatatt tgtttgtata ccccttctaa
     7501 aatcggtagt ttccattcaa ttgatgggta ctagttgatt ttaaaaacta tgcttattca
     7561 attttttatt ttagctcata tatttcgttt ctttctaaat tttatactga tgaaaacaag
     7621 tagcacaccc aatattgaca atataaactg gctaatgatg gtttctccag tttttggaag
     7681 atgcttattt ccactgcttg ttggattgtt tcctcttata tctgagctat cagcaacttt
     7741 tctattctct tttgttaaaa agatcgccac ttcttgttct ttttcgatct tgaaagttac
     7801 tggtgtcgca tc
//
LOCUS       DAZAOD010000111         7607 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000111 DAZAOD010000000
VERSION     DAZAOD010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.113"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            145..618
                     /locus_tag="ACHDPO_002509"
     CDS             145..618
                     /locus_tag="ACHDPO_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFN3370094.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            615..2747
                     /gene="feoB"
                     /locus_tag="ACHDPO_002510"
     CDS             615..2747
                     /gene="feoB"
                     /locus_tag="ACHDPO_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFN3370095.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            2749..2883
                     /locus_tag="ACHDPO_002511"
     CDS             2749..2883
                     /locus_tag="ACHDPO_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFN3370096.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            2977..3621
                     /locus_tag="ACHDPO_002512"
     CDS             2977..3621
                     /locus_tag="ACHDPO_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3370097.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            3808..5001
                     /locus_tag="ACHDPO_002513"
     CDS             3808..5001
                     /locus_tag="ACHDPO_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFN3370098.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            4994..6721
                     /locus_tag="ACHDPO_002514"
     CDS             4994..6721
                     /locus_tag="ACHDPO_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFN3370099.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            7115..7312
                     /locus_tag="ACHDPO_002515"
     CDS             7115..7312
                     /locus_tag="ACHDPO_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFN3370100.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            7314..>7607
                     /locus_tag="ACHDPO_002516"
     CDS             7314..>7607
                     /locus_tag="ACHDPO_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFN3370101.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYG"
BASE COUNT         2496 a         1287 c         1674 g         2150 t
ORIGIN      
        1 tatcacaagt ataattgaca ttctcaatta ccgagagtat tctatgtgag aatgattctc
       61 atttatttgc gtaacacgta agaaaattag aacatataat gaatgatttt aatacatgat
      121 ttatttcaca agagaggaat caatatgcag accttagcgc aggcaaagca gaatttcgtt
      181 tatcaagtcg aacgaatcga aacagaagaa aaaacaaaac gccatttgca aaatatcggg
      241 atcgttgccg gaagtaaaat cgtcgtcgtc aatttatcag gcaacaatgc cattttactg
      301 gtaaaaagtc atcgagtggc agtaagtcgg gaaatactag gtcaaatctt tgtcaataaa
      361 aagactgctt cctctgaaag ctggacttct cttgatcaat taaaagcagg agagactggg
      421 atcgtcgtag caatccacgg acaaggcgca gtgaagcgac ggttaatgga tatgggattg
      481 acgcgaaatg taaaaatagt tatccgaaaa ctagcccctc tgggagatcc aatcgaactg
      541 acagtgcgag ggtatgaact gacgttacga aagtcagagg ccgaactaat cttgatacaa
      601 agggaggaaa aagaatgaat atcgcgttag tcggaaatcc aaacagcggg aaaactagct
      661 tgttcaatct cttgactggt tcgaatcaat atgtagggaa ttggccgggc gtaacagtag
      721 aaaaaaaaga aggatcgttg aaaaaaaatc cgaacattca tattcaggac ctacccggca
      781 tctattcttt gtctccttat acaccagaag aagtgattgc aagagattat ttggttcagg
      841 aacagcctga actgatcatc aacattattg atgctaccaa tttagaacga aatctttatt
      901 taactacgca gttattggat ttagacattc ctatgatcat tggtctgaat atgatggatg
      961 tcatcaaaaa agaaggaaaa aaaatcaatc tagaaaagct ttcctatggt cttggtgtac
     1021 cagttttacc aatcagcgta ttgaaaaagc aaggaatcga aaaactaatc gaaaagattc
     1081 aggagtctgc aaaaaagcgg ccttctattc ctgttccctg tacatatgat ccacgtttag
     1141 aagcagcttt acatgaaatt gaagatgtac taggagaaca aagcggcaag aaacgctggt
     1201 atgcaatgaa atattttgaa cgagatcaga aggtaagaga ggattacgag atagcagttt
     1261 ctcagcaaaa agagatcgag caactgatcc agttaacaga gaaactattg gacgacgata
     1321 gtgagacgat tctggtcaat gaacgttatg aatttattac ccaactatgt acactctgtg
     1381 ttgtgtcaaa tgattctttc caattatcga tgagtgacaa aatcgatcag attgcaacga
     1441 atcgttggtt agccttgccg atcttcgcat ttgtgatgtg gctgatctat tatctggcta
     1501 ttcaaacagt aggaacaatg gggacagatt ggatcaatga cacattgttt ggtacatggt
     1561 taccagaaca tgttggcaga ttgttagctg aatggcaagt agcgggatgg atgcaggagc
     1621 tgatcttgaa cggcatcatc gcaggcgtgg gagcagtgtt aggatttcta ccgcaattga
     1681 ttatattgtt tttatgcttg agctttctgg aagactgcgg atatatggcg aggatcgctt
     1741 ttgtcatgga tcgacttttc aggaaattcg gtctttcagg aaaatccttc attcctatgc
     1801 tgattgctac aggatgtgga gtgccaggcg tcatggccag tcgcacgatt gaaaacgagc
     1861 aagatcgtcg tttgacgatc atggtcacaa ccttcatgcc ttgttctgca aagttgccga
     1921 ttattgcctt agtagcaggg gccttttttc ctcatcaatc ttgggtagct ccttctgcct
     1981 attttcttgg tatgactgca attattttct ctggaatcag cttgaaaaaa acacgtttgt
     2041 ttgctggaga tacagctcct tttatcatgg aattgcccgc atatcatttt cctcaatggt
     2101 cagcggtcct aagacaaacc tatgaccgca gcaagtcttt tgttaaaaaa gcaggaacga
     2161 ttatctttgt ttctagtatc gtgatctggt tcagctcttc ttataatttt tatgctcaac
     2221 ctgtttctga agaccaaagt atcttagcct ttttcgggcg aatcctggca gttgtttttc
     2281 agccgcttgg ttggggaaac tggcaaggaa cagtcgcagc gattacagga ttggtcgcta
     2341 aagaaaatat tattggcaca tttggtattt tgtttggtca tgcggaagta tccgaaaatg
     2401 gcagagaaat ctggcaagtg ctacaacaca catatactcc cgcagcagct tattcattgt
     2461 tagccttcaa tttactttgt gcgccttgtt ttgcggcaat tggggctatc catcgggaaa
     2521 tgaatgccaa gaaatggact tggatcgcca taggctatca atgcggttta gcttatttag
     2581 ttagttttgt gatttatcag ttgggacact tattggaggg tggacaggta gcgttaggga
     2641 cgtatcttgc tattttactg atgataggac tcgtttatgt tttgttccgt cagccaaaat
     2701 ccaagaacca gttttatact atattgtcat tagaaggaga ggaataggat ggcgacattc
     2761 ttattaagtg tgttaatctt tggaagtgca ggcgcaattg tctatactcg tttaaaatcc
     2821 ggtaagaatt gtgatgactg tcaaacagct tgcccagtaa aaaaggaaca gatcaagcga
     2881 tgatcagtcg ttgcaagagg ctattctccc cttttttgct tattttgcta gagcatagta
     2941 agatgaggga aagtaaaaaa agaaagagga aagaaaatgt ctggaaagaa aaaaatcgtc
     3001 cgcccgcgct accagcagat tgctgttgat ttagccgaac gtatcgttga aaaccgatat
     3061 aaagtgggtg agaagatcca tgcccgctca acacttgcca gtacgtacaa tgcttctcct
     3121 gagactaccc gcaaggctat caatgtgctg gtagatcttg gaatcatgga agtacggcat
     3181 ggaagtgggg catttgttgc ttcgaaggaa aaagcaaaag atttcctatt gcaatatcaa
     3241 gatgtacaat ccatccaaga tacaaaagca gaaatcatgg caagtgtgga gaagcaacaa
     3301 gatgagctga atcatttttc tcaattattg gatcagctgg tcaatcaaac gaagcgaata
     3361 cataagatga atcctttact tccgtttgaa ttatctttat cagaaaaagc aatgcatctg
     3421 gaccgttcaa ttagcgagtt gaatatctgg caggcgactg gcgccacagt tatcgcaatt
     3481 tctcataatg aagaactgct tgtttcacct ggcccctatg ctaaatttac ggcaggggac
     3541 atcgttcatt ttattggaaa tgaatataca ctacagcgta tgacaaactt tttttacccg
     3601 gagcatcagc ttgcagaatg attgtgtgaa atattaaaaa aatattaact tggctaaacc
     3661 ttttatttac aaagatttag ccaagttttt ttcagtttgg acaagcaaat ttctttcatt
     3721 tttgacaaag tgactacatg atgttaacat agtgtggtca cttttttcag aaagaaaaat
     3781 gaatttacat aaaaaaggag aatttgtttg gtaaaagtag aagtaaaaca tttaacaaag
     3841 atatttggta aaaagacaca agccgcttta gatatgatga atgatcacca gccgaaaacg
     3901 gagattttaa agaaaaccgg tgcaacggtt ggtgtgtatg acgtgaattt tgacgtaaaa
     3961 gaaggagaaa tcttcgtgat catggggctt tccgggagtg ggaaatccac attgatccgt
     4021 ctattgaatc gtctgattga gccaacttcg ggcagtatct atattgatgg agaagatgta
     4081 tcgaagttaa gcaaagaaga attgcgagaa gtccgtcgtc ataaaatcaa tatggttttc
     4141 caaaacttcg gtctgtttcc acatcgaacg atcttggaaa atacagaata cgggttagaa
     4201 gtccgtggtg tacctaaaga agaacgacaa gaaaaagcag aaaaagcatt agaaaattct
     4261 agtttgcttt catttaaaga ccaatatcct agtcagttat ctggtgggat gcaacaacgg
     4321 gttggcctag ccagagcttt agcaaatgat cctgagatct tgctgatgga cgaagcgttc
     4381 tcggctcttg atccgctgat ccggcgagaa atgcaagacg aattactgga cctgcaagcc
     4441 aatgttcaaa aaacgattat tttcattacc catgatttga atgaagcttt acggattggg
     4501 gacagaatcg ccttgatgaa agacggcgaa atcatgcaga tcggaacagg tgaagaaata
     4561 ttgaccaatc cagcaaatga ttatgtacgt gaatttgtgg aagaagtcga tcgttccaaa
     4621 gtgcttacgg ctcaaaacat catggtacct gcattgacga cgaatatcga atctgatgga
     4681 ccaaacgttg cattgacaag gatgcgtaat gaagaagtca gcatgctgat ggctgttgac
     4741 agaaagagac acctgaaagg gatcatcact gcagatcaag cgttagaagc taggaagcaa
     4801 aaacgtccat tgatcgactt cctagatgaa aatgtgacgg tgattgggaa agacatggtg
     4861 gtaagtgata ttttcaatat tatttatgac tcaccgactc cacttgcagt tgtagaggat
     4921 ggaaaattaa aaggtgtcgt catccgaggt agtgtgattg aagcattagc agaaacaagc
     4981 gaggtgagtg aacatgaata atctattgaa ctatcaatta ccagtggcaa actgggtaga
     5041 aaatatcaca gaatggttta cgacaacttt ttctggccta ttttcatttt tacaaacgat
     5101 tggacaggca gtgatgtcgg ggattacaaa tttactgtta gtgattccag ctcctttgtt
     5161 tatcttgtta ttgacggtag cagctttctt tatttctaag aaacgtccag gacttacgtt
     5221 gttcacatta atcggtctat ggtttattta taaccaaggt ctatggaatg atttgatgaa
     5281 tactgtcaca cttgttcttt tatctagtgt gatctcgatc atcattgggg taccattagg
     5341 gatcttgatg gcaaaaagca gtaaagccca aagtattatc aaaccgatcc ttgactttat
     5401 gcagacaatg ccaggattcg tttatttgat tccagcagtt gcatttttcg gtatcgggat
     5461 ggttccaggg gtatttgcct cagtcatctt tgctctgcca ccaaccgttc gttttacgaa
     5521 tttagggatt cgacaagttc ctaaagaatt agtagaagct tctgattcat tcgggagcac
     5581 aagtcgtcaa aaactattca aactagaatt gcctttagct aaaagtacga tcatggcagg
     5641 gatcaatcaa acaacaatgc tgtcactttc aatggtcgtt attgcctcta tgatcggtgc
     5701 acccggctta ggacgcggcg tattatcagc attgcaaaga gcacaagtcg ggaatggatt
     5761 tgtcaacggg gttgcattag ttatcttagc aatcatcatt gaccgtttta cacagcattt
     5821 gaaccagcca aacaataaaa aagctgcagg agcaacaaca cagaaaagta aaaaacgtca
     5881 aggactgatc attggtgctg tagtagtagt gatcttaggt gcgattggta tagggagttt
     5941 ttcatctgcc aaagaaacaa aacgtatcaa cttatcttat gttgaatggg atacagaagt
     6001 tgcttcaaca aatgtagtcg gtgaagtatt gaaacaaatg ggctatgatg taacgatgac
     6061 gccattagat aattcaatca tgtggaaatc tgtttcaaat ggcgagtcag atgccatggt
     6121 ttcagcttgg ctacctaaaa ctcatggttc acaatatgca caatataaag atcaagtcga
     6181 agacctaggt gccaatttga caggagcaaa agttggttta gcagtgccag cctacatgga
     6241 tgtaaattcg atcgatgagt taaccgatca ggcaggtaag aaaatcatag gaatcgagcc
     6301 aggagctggt gtagttacgg ctgctgaaaa cacgatccaa aaatatgaca acttgaaaga
     6361 ctggaaagta gagacatctt cttcaggagc aatgaccgtt gcactaggtc aagcgatcaa
     6421 aaaacacgaa ccaattgtag ttacaggatg gacacctcat tggatgtttg ccaaatatga
     6481 tctgaaatac ttagaagatc ctgaaaacgg aatgggaagc gaagagcaga tccatacgat
     6541 ggttcgaaaa ggattgaaag aagaccagcc agaagcttac aaagtattag acaatttcca
     6601 ttggtcagaa aaagatatgg aaaaagttat gttggaaatc aacaatggaa aagatccaca
     6661 gcaagcagca aaagactgga tcaaagagaa ccaagaatta gtcgaaagct ggaaaaaata
     6721 aaaagacaga cacgaaataa atggagcttc caaaattgga tcaaatatcc aaatttggaa
     6781 gctccatgtt cgtctctatc ttttttgtct ataaaaaaag agaatgcgta gctcatcttc
     6841 gaaacgttca aagacgccga caaactatta tgaatttatg ggtgcgagtc aaagagatcg
     6901 atcgtaggta tgaaagacta atgtgattaa agtttattat gtacgaagtg cattctcaaa
     6961 aaatattaaa gaatatacat agtttatata cttaaaagtg attaaattct tattcaggaa
     7021 ttattttgct acgtttcaag aaggaattgt tttttgaaat ttaatgaatg ttagaataat
     7081 agtctaaaaa cattaattta ggggtgatta gattatgaaa catttaaaaa ttttgtctat
     7141 taaagagaca caacttatct atgggggtac cactcatagt ggaaaatatt atggaaatgg
     7201 agtgtattgc actaaaaata aatgtacggt cgattgggcc aaggcaacta cttgtattgc
     7261 aggaatgtct ataggtggtt ttttaggtgg agcaattcca gggaagtgct aaaatgaaaa
     7321 aaaatgctaa gcaaattgtt catgaattat ataatgatat atctataagt aaagatccta
     7381 aatattctga tattcttgag gttttacaaa aggtatattt aaaattagaa aaacaaaaat
     7441 atgaattaga tcccagtcct ttaataaata gattggtgaa ttatctatat tttactgctt
     7501 atactaataa aataagattc actgaatatc aagaggaatt aataagaaat ttgagtgaaa
     7561 ttggaagaac tgctggaata aatggtttat atcgagcaga ttatgga
//
LOCUS       DAZAOD010000112         7560 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000112 DAZAOD010000000
VERSION     DAZAOD010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.114"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            268..591
                     /gene="relB"
                     /locus_tag="ACHDPO_002517"
     CDS             268..591
                     /gene="relB"
                     /locus_tag="ACHDPO_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFN3370102.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            911..1138
                     /locus_tag="ACHDPO_002518"
     CDS             911..1138
                     /locus_tag="ACHDPO_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFN3370103.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            1154..2320
                     /gene="hemW"
                     /locus_tag="ACHDPO_002519"
     CDS             1154..2320
                     /gene="hemW"
                     /locus_tag="ACHDPO_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFN3370104.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            2555..3598
                     /gene="hrcA"
                     /locus_tag="ACHDPO_002520"
     CDS             2555..3598
                     /gene="hrcA"
                     /locus_tag="ACHDPO_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFN3370105.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            3692..4255
                     /gene="grpE"
                     /locus_tag="ACHDPO_002521"
     CDS             3692..4255
                     /gene="grpE"
                     /locus_tag="ACHDPO_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFN3370106.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            4306..6135
                     /gene="dnaK"
                     /locus_tag="ACHDPO_002522"
     CDS             4306..6135
                     /gene="dnaK"
                     /locus_tag="ACHDPO_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFN3370107.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            6286..7452
                     /gene="dnaJ"
                     /locus_tag="ACHDPO_002523"
     CDS             6286..7452
                     /gene="dnaJ"
                     /locus_tag="ACHDPO_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFN3370108.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
BASE COUNT         2585 a         1285 c         1671 g         2019 t
ORIGIN      
        1 agtaattctc gttccttcct gtagtaatat tttttaaata acctataggc ttcttcaaaa
       61 gtacatcctc cagtaaattc taagtactgg aggattcttt ttctagtgtt gctttactca
      121 tgaaaaagta gttggctact tcatcaaaat ttctgaactt ttttaatgta taataaagag
      181 ctcgatcatt tactacaagg atgctagctc ctacattttc acagtttttt agcaagtaaa
      241 tttttctaaa atcacatcag gaaatgcatg agattcttta agagaggcaa ttatagggct
      301 atgattacgg ttcgtgtaag tgacgccaaa aaagaatggc tttcttatat ggctgaattt
      361 tatgggatta ctttatctga acttctaaaa aactattcga tggaacaact agaagatgaa
      421 tacaatcgtc aaacggctga aattgcccat aaacattgga taagaagtgg gaaaacaaca
      481 gtattcatgg aagaatcctt aatgaatttg gtgggctgga atgacctgcc gtttaaaatt
      541 cacgcccgaa attcagaagc agctctgatt ggcaaatacg tgtattggta gagatagaag
      601 ataatcaatt cgttgttatc gctattcaag tagggcaccg aagaaatgtc tatgattaag
      661 agactgttta tttttacaaa aaaataataa ttggaatcta gttaaaactc ttgaagtgag
      721 agatttgact agattttttt atgaataaaa taaggacaaa attgtttagg aagaatcatg
      781 agtgtaaaaa aatcatccaa gaagtcgatt cttggatttt ttagtggatt tgttcgccaa
      841 atacgtttag tatgcgtata tgagaggttg taagcaaagc gttgtggtct gagcacttaa
      901 ggaggaatct gtgaaaatag cttttcatat ttttgcagat tttgacttaa tgccgaaggt
      961 cagctttgcg attaccgttt atcgagaggc tgtaaaagca ccgtgtagct ccgatgacaa
     1021 taagcaagca tttttagagc taggtttcct tgattctaaa tatgcggctt atttcaatga
     1081 gttggtgctt gaacgcgatt ttaagaaggt cgaaaacagg cacgactttt cgacgtaagg
     1141 agaaagaatt tcaatgatag aaacaataaa tcccgcagaa aacaaggttt ctgcgtacat
     1201 tcatatccca ttttgcgagc atatctgcta ttactgtgac tttaataaag tttttttaga
     1261 agggcagcca gtagatgagt atgtggaaat gctgctgaat gaaatgagat taatgctgga
     1321 aagtcatcct acagcgaatt tggaaacact ttatgtagga ggcggaacac caacttcttt
     1381 atctgctaaa caacttgatc gactattatc aggtgctaga gagatcctgc cttttcaaaa
     1441 tggtaatgag tttactgtag aagcgaatcc tggtgatttg acccgtgaaa aacttcaagt
     1501 gatgaaaaac tatggcgtca atcgtttatc catgggagtg cagacatttg acaatcgctt
     1561 attgaaaaaa attggacgta aacatactgc agaagatgtg tatcaaacaa tgcaattttt
     1621 agaagcagaa aattttacca atgtaagcat cgatttgatt tatgcattac cgggacaaac
     1681 actagaagga tatcgggata ctttggaaaa agctttggct ttggatctgc ctcactattc
     1741 tttgtactca ttgatcctcg aaaacaaaac aatgttcatg aactgggtac gacaaggaag
     1801 actcgaactg cctgatcagg aaacggaaac cagaatgttt gaagagacga ttgaagcaat
     1861 ggaaaagcat ggacgtcacc aatatgaaat aagtaacttt gggctctccg gacatgaatc
     1921 tcaacataac ctcatgtact ggaacaatga ccactatttt gggtttggag ctggtgctag
     1981 cggttatctt ggagatattc gttaccgcaa caaaggacca atccaacact atttacgccc
     2041 attacgagca aatgaacgcc cggtattgga agaagaaaaa ttgacacgaa aaaatcaaat
     2101 agaagaagaa atgttcttag gactaagaaa aaaaacaggg attactaaaa aacatttcta
     2161 tgatcgctat caaaaaacaa ttgaatcggt gtacggtgat gtgctaaggg aattagagca
     2221 agaagggtta cttgttaatg aagaagaccg tgtttatttg acaccaagag ggactttttt
     2281 ggggaacaat gtgtttgagc gctttttatt tgaaaaatag tttgaagaat atttgttttt
     2341 tatcgaaact tgaaaagaaa aagtttagaa agtttgacaa tgaggtattg aagtattgat
     2401 ataactggat ttacatcaat tatttagaat tagcactctt gtgtttagag tgctaaaaaa
     2461 tggagtcttt ctcttgacag gagaagggct tcttgctata tttataagtg aattagcact
     2521 tagaatatat gagtgctaat gagaggtgag gaagatgtta acaaagcgac aaaacgacat
     2581 tttacgtctg atcatccaac actatacgag tagtggcgtg cccgttggtt ccaaaacatt
     2641 aatgtctgag ggagtcaagg ccagctcagc aacgattcgc aatgatatga aagcattaga
     2701 agatgaagga ttgctgttga agactcactc ttcttctggg cggattccat ctgctttagg
     2761 ctatcgttat tacgtggatc atttgttaaa acctgctcgc gtagcagaag atgatttgct
     2821 gctgattcgt cagtctctag gcagagaatt tcatgaaatc aatgagatta ttaagcaatc
     2881 tgctgagata ttatctgagc tgacaagcta tacgactttt tcattgggac ctgaaataaa
     2941 agaccgccga ctgactggct ttcgtatcgt acccttgaat aatcgacaga ttattgctat
     3001 cgtcgtaaca gatatgggga atgtagaaag ccaagtgttc actcttcccg aatatatggg
     3061 aagtcaggaa ctagaaaaaa tggtacagat tgtaaacgac cgtctagtcg gagatcctct
     3121 gatgacggtg taccataaac ttcgtacgga gattccgatg attcttcata aatatttcca
     3181 gacgacagaa gggatgtctc agttatttga caccgttctt ggtcatgttt ttgaagaaaa
     3241 ggtttatgtc agtggacaaa tgaatctctt ggattatgag ccccgtcaag atcttgatca
     3301 gttcaaatcg atgttttctt ttatgaaaga ctcagacgga cttacacaaa tgatcactcc
     3361 gatggatagc aatattcata tcaagattgg tgctgaatta ggcaatgatt tattgcagaa
     3421 tatgagtatg attcaagcaa gttacgagat agatggtcat ggaagaggta caatagcctt
     3481 gttagggcct actagtatgc cttattctcg gatgttcggt ctagtcgatg tttatcgaag
     3541 agaactagca gctaaacttg ctgattacta ccgctcgctt gacttgtcaa actcgtaatg
     3601 tgaataacga agctatttgc agctgatcgt tctctctttc ttagtaagag caatcaaaca
     3661 gctgactgaa taatgaaagg aagactgtat cgtgaaagaa aatcaagaag aactagataa
     3721 agaaatgaca gatgctcagc cagaaccgga aatcgatgtc gaagctgcag aagattcggg
     3781 tatttcagaa gctgaagcgg aagaattcga aacagcgaaa ttaaaagctg agttagaaga
     3841 aatggaagat aaatacttgc gggctcgtgc tgaaatcgca aatatggcaa atcgaggaaa
     3901 aaatgagcgt gagcaattac aaaaataccg ttcacaagat ttagccaaaa aattacttcc
     3961 atcaattgac aacctggaac gtgcattagc cacagaagtg tcagatgatc aaggggcagg
     4021 tttgaaaaaa ggcgtggaaa tggtcttgga aagtttgcgt aacgcactgg aagaagaagg
     4081 aattgaaaaa atccctgcta aaggagaagc ctttgatcct aatcttcatc aagcagtaca
     4141 aactgttcca gcgactgaag atacaccagc cgatacgatt gtagaagtac tacaagaagg
     4201 ctacaaatta catgatcgcg tgttaagacc aactatggtc attgttgcac aataattgtg
     4261 cggatataaa acttacactt tcaattaaag aaggagacgt taattatgag taaaattatc
     4321 ggtattgact taggtacgac taactctgca gtagcagtat tggaaggaaa cgaagcaaaa
     4381 atcatcgcta acccagaagg aaaccgtaca acaccttctg ttgtatcatt caaaaatgga
     4441 gaaatccaag taggggaagt tgcaaaacgt caagctgtga caaacccaaa tacgatttca
     4501 tcaatcaaac gccatatcgg tgaagcaggt tacaaagtag atgtagaagg taaatcatat
     4561 acaccacaag aaatctcagc aatgatcctt caatatatca aaggattcgc agaagactat
     4621 ttaggtgaaa aagtcgaaaa agcagttatc actgtgccag cttactttaa tgatgcacaa
     4681 cgtcaagcaa caaaagatgc tggtaagatc gctggtctag aagtagaacg tatcgtcaat
     4741 gaaccaactg cagctgctct tgcctatggt ttagataaaa cagatcgcga cgaaaaaatc
     4801 ttagtattcg accttggtgg cggtactttt gacgtatcta tccttgaact aggagacggt
     4861 gtctttgatg tattgtcaac agctggcgac aaccatctag gtggggacga ctttgataac
     4921 aaaatcatcg actacatggt agcagaattc aaaaaagaaa acagcattga cttgtctcaa
     4981 gacaaaatgg ctttacaacg cttgaaagac gctgctgaaa aagcgaaaaa agatttatct
     5041 ggcgtatcaa gcacacaaat cagcttgcca tttatcacag caggagaatc tggaccattg
     5101 catttggaaa tgacattgac acgtgcaaaa tttgatgaat taacagctga cttagtagaa
     5161 cgtacaaaag taccagtacg tcaagcgtta aaagatgcag gtctgtcaca atcagaaatc
     5221 gacgaagtta ttttagtcgg tggatctact cgtatccctg cagttgtaga agcagtacgt
     5281 aaagaaacag gaaaagaacc aaacaaatca gttaaccctg atgaagtagt tgctatgggt
     5341 gctgctatcc aaggtggcgt gatcactggt gatgtgaaag atgttgtttt acttgacgtt
     5401 acaccattgt cattaggtat cgaaacaatg ggtggagtgt tcactaaatt gattgaccgc
     5461 aatacaacga ttccaacaag taaatcacaa gtattctcaa ctgcggcaga taatcaacca
     5521 gcagtagaca tccatgtatt acaaggtgaa cgcccaatgg ctgctgacaa caaaactcta
     5581 ggaagattcc aattgacaga tattccagca gctcctcgtg gtattccaca aatcgaagta
     5641 acattcgata ttgataaaaa cgggattgta aatgtatctg cgaaagatct aggtacacaa
     5701 aaagaacaaa aaatcacgat caaatcttct tcaggtctaa cagacgaaga aatcgaacgt
     5761 atggtgaaag atgcagaagc aaacgctgaa gcagataaag ctcgtaaaga ggaagttgac
     5821 ctacgtaatg atgtagacgc attgctattc tctgtggaca aaacattgaa agaattagaa
     5881 ggcaaagtgg acgaagaaga agtgaaaaaa gcagaaacag ctcgtgacga attaaaagcc
     5941 gctgttgaag caaacaacat cgaggaaatg aaaactaaac gcgatgcatt gaacgaaatc
     6001 gttcaaaact tgactgttaa actatacgaa caagctgcac aacaacaagc tcaagaaaat
     6061 ccagaagcag ctcaaggcgg agcagatgat gtcgttgatg ctgattttga agaagtcgat
     6121 ggcgacgata aataatcagt tcactgaatt tcgagagaag gccaaagttg ctactttggc
     6181 tttttctttt gaaaaatagt ttgaagtatc ggtttttgtt tcaaacaaaa tatgatatga
     6241 taacaagcga cgtgaaaatg atgagaacca ataggaggaa agcctatggc aacaaaacgt
     6301 gattattatg aagtcttagg gctctcaaaa ggagcatcag aagatgaaat aaagaaagct
     6361 tatcgtaagc tttcgaaaaa ataccatcct gacatcaata aagaacctga tgcggaagaa
     6421 aaattcaaag aagtatcaga agcatatgag attttaagtg acccgcaaaa acgcgctgca
     6481 tacgaccaat acgggcatgc aggcacagat ccaaattacg gtgctggtgg agctggtggc
     6541 ggatttggtg gattcggcgg cttctctggt ggcggcttcg gtggttttga agatatcttc
     6601 gactctttct ttggaggagg cggtcggtca gtcgatccaa atgcgcctcg tcaaggtgct
     6661 gatttgcaat atacggtcga cttgtctttt gaagaagcga tttttggtgt agaaaaagaa
     6721 atcaagtata atcgggaaga aatctgtcat acttgtggtg gaaacggtgc aaaaccaggc
     6781 acacaaccaa ctacttgtca taaatgtcat ggtgcaggta cgatcaatgt agaacgccaa
     6841 acgccacttg gacgagtgat gagccgtcaa acttgtgatg tttgtcatgg cacagggaaa
     6901 gaaatcaaag aaccttgtcc aacctgtcat ggctcaggac atgagaagaa agcacattca
     6961 gttaaagtga atgtaccagc tggtgtagaa gaaggacaac aaatgcgttt agctggtcaa
     7021 ggagaagctg gagaaaacgg cggaccattt ggtgatttgt atgtggtttt tcgtgtagaa
     7081 gaaagtgata tctttgatcg tgaaggttct gaaatttact atgaattgcc tttaagtttt
     7141 gtacaagcag ctttggggga tgaagtccaa gtaccaactg tccatggaga tgtgaaattg
     7201 aagatccctg ctggaacaca gacaggtacg aacttccgtt tacgtggaaa aggcgctccg
     7261 aagttacgtg gtggtgcaac aggcgaccaa catgtcaaag taaaactgat cacaccgaaa
     7321 aatctaaatg aacaacaaag agaagcatta cgtgcattcg ctgaagctgg cggcatcaaa
     7381 gttgaagaac agcaagaaga cggtttcttc gataagttta aagatgcttt tggcgggaaa
     7441 aagcggaagt agtttttcta gtaaaaatat aaagtagact tgcccaaatt ttctatttct
     7501 agtaaaaacg ctaagtcatt aataattaaa aaccagacga acaatcatac gttcgcctgg
//
LOCUS       DAZAOD010000113         7390 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000113 DAZAOD010000000
VERSION     DAZAOD010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.115"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..2124
                     /locus_tag="ACHDPO_002524"
     CDS             <1..2124
                     /locus_tag="ACHDPO_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370109.1"
                     /translation="SLFIYQNTYESIESSYLTDKKNLLRQVKTNVEWKIRTIEYSFST
                     YGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFIETIVMDDNNYDLVSLAGKWGVINGS
                     LSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIEMVISLPMFEKEKYALGIATIEKHTI
                     EQVVGESGEDILSIENEVGNLFTTQTVKNKEQPTVLTDVDLDYNQLKVIREKDKTYIV
                     LKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAVSLTLVGLIGLLSYLFSDRFARPISQ
                     IQERLNLKSKGFSGKELDLVAQSVSRIIGEKEALSAHLVTQKPQLETLFVLSLFRNRV
                     ERRELDQRLQQFGYSSQNDCYYTALVQIDLLEDSHGGERDLLLLAINNMITEIVPKEN
                     RMLPIVLNEEMQATIYRMDKDDAEASKKVMEYCRLIQKRVKEYLNLTISIGISNRFET
                     LNESKQSVDRAKEALYYRVNTGPSSIIFYQEIVPAAHEKTLIRYPIEEQNRLFEAIRS
                     GNQEVKNLVHELIDALFAQNKNPLSREVVSVRLINELVQLGQLLGVDSKNFDNMKQIY
                     VKALNNYHPKELEKLVLEQLVLPITECSQAITDHEFKNLSENIMHIVYTEYDRDLSLD
                     VIADRLHYNPNYLSNVFKKETGEKFGDFVQNHRLEVAKKWLKETNLSVKEIAERLQYR
                     NPQNFIRFFKKKESITPGEYRKKYL"
     gene            complement(2582..3454)
                     /locus_tag="ACHDPO_002525"
     CDS             complement(2582..3454)
                     /locus_tag="ACHDPO_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFN3370110.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            3754..4728
                     /locus_tag="ACHDPO_002526"
     CDS             3754..4728
                     /locus_tag="ACHDPO_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3370111.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            4750..5442
                     /locus_tag="ACHDPO_002527"
     CDS             4750..5442
                     /locus_tag="ACHDPO_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFN3370112.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            5408..6916
                     /locus_tag="ACHDPO_002528"
     CDS             5408..6916
                     /locus_tag="ACHDPO_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFN3370113.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            6990..>7390
                     /locus_tag="ACHDPO_002529"
     CDS             6990..>7390
                     /locus_tag="ACHDPO_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFN3370114.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQI"
BASE COUNT         2546 a         1214 c         1495 g         2135 t
ORIGIN      
        1 agtttattca tttaccagaa tacctatgaa tcgatcgaat cgagttattt aacagacaaa
       61 aagaatttgc tcaggcaagt taaaactaac gttgaatgga aaattagaac gattgaatat
      121 tcgttttcta cgtatggttc gaccaaaaat ttctcggaca tattcaagca tccgctgaca
      181 tatacagatt actccactta ttctgaaatc aggaaagaac taaattttat agaaacgatt
      241 gttatggatg ataataatta tgatttagtc agtttggctg gtaaatgggg agtaatcaat
      301 ggatcgttga gtcaactgac cgaagaggaa gttgaaaagt atcaacagaa gtacataaat
      361 aacaaaaata atttattttg gcaaaagaaa aacaaaggaa tcgaaatggt gatttctttg
      421 ccaatgtttg aaaaagaaaa atatgcattg ggaattgcta cgatagagaa acatacaata
      481 gaacaagttg ttggtgaaag tggagaagac atactttcta ttgaaaacga agttggcaac
      541 ctttttacta ctcagacagt aaaaaataaa gagcaaccaa ctgtattaac ggacgtggat
      601 ctagattaca atcagctgaa agtgataaga gaaaaagata aaacgtatat agtactgaaa
      661 tcagattata ataattggat ttacagatta gaagttgact ctagtgcaat tggcgcaatg
      721 atccgcaatc tgagaatcgg gctagttgca gtgtctttaa cactggtagg actcattggt
      781 cttctttcct acttattttc ggacagattt gcccgtccga tttctcaaat acaggaacgt
      841 ctgaatctta aatcaaaagg attcagtggg aaagaactag atttggtcgc tcaatcagtc
      901 agtcggatca taggagaaaa agaagcgtta agtgcacact tagttaccca aaagccacag
      961 ctggaaacgc tatttgtact tagtttattt agaaatcgag tagaaaggcg agaactagat
     1021 cagcggttgc agcaatttgg ttatagttct caaaatgact gctattatac agctttggtt
     1081 caaatcgatc tgttagaaga tagtcacggt ggggagcgtg atttgctact tttagcgatc
     1141 aacaacatga tcacggaaat tgtgccaaag gaaaatcgaa tgctgccgat cgttttgaat
     1201 gaagaaatgc aagccactat ttatcgaatg gataaagatg atgcagaagc aagcaaaaaa
     1261 gtcatggagt attgccgact cattcaaaaa cgtgtaaaag aatacttgaa tttaactatc
     1321 agtataggca tcagtaaccg gttcgaaacg ctgaatgaaa gcaagcaatc ggttgatcgg
     1381 gcaaaagaag ccctgtatta tcgtgtaaat actggtccaa gttcaattat tttttatcag
     1441 gaaatcgttc ctgctgctca tgaaaaaaca cttattagat atccgataga agaacaaaat
     1501 cgattgtttg aagccattcg ttctggaaat caggaagtga agaatttagt acatgaattg
     1561 attgatgcat tgtttgcaca aaataaaaat cctttgagtc gggaagtagt ttcggtccgc
     1621 ttgatcaatg aactcgttca attaggacag ttattgggag tagattcaaa aaactttgat
     1681 aacatgaaac aaatttatgt aaaagcactg aacaattatc atcccaaaga actagaaaaa
     1741 cttgttttag aacaattagt tctgccaatc acagaatgct ctcaagcaat cactgatcat
     1801 gaatttaaaa atttgtcgga gaatattatg catatcgtct acacagaata tgatcgtgat
     1861 ctgtctttag atgtgatcgc tgataggttg cattataacc ctaactattt aagtaatgta
     1921 tttaaaaagg aaacaggaga aaaatttggt gattttgttc aaaatcatcg tttagaggta
     1981 gcaaaaaaat ggttgaaaga gactaacctc tccgtaaaag agattgcaga aagattgcaa
     2041 tatcgaaatc cgcaaaattt tattcgtttc tttaaaaaga aggaatcgat tacgccggga
     2101 gaatatcgaa aaaaatattt gtgaatcaag aggctgtttt tcttgtggac tgattcaagc
     2161 aataaaagaa gttagaataa ccctagtatt tgtatttatg gatagttaaa tttcaaggct
     2221 aagcacgcaa aaagaactgt gacaaaagtc ttgtcacagt tcttttttac gaataaatgg
     2281 cgttcaagag acaggctatc gacaataagg cataattttg tgaaatatgg gaagctattt
     2341 ttcaaaatcg cttcttattg ctcctgtggg ttactcgtcg caatgtttgt gagagttttt
     2401 atcatcgctc aaggctgaac gtctctttca caacctctga tacacggtgt tccaggagta
     2461 gattcttcga aaaataagcc gaaatttcac aaaaatttaa gaagcaattt tcgtaaatgc
     2521 cttcttattt cttgaagctg accacttctg acacaactac cattttgcgt tcagtacata
     2581 atcacccttt gacagaacct acgagtgctc ctttgacaaa atatttctga acaaaaggat
     2641 aaacaatcag cataggcact gttgcaataa cgataacagc cattttaact gtttgtgctg
     2701 gtggaatcac atcaacggca ctactttctg cttgcatccc acttgataca atgacgattt
     2761 ggcgtaaaag aatctgtatc ggccatttag atgaatcgtt gatatacaaa atagcagtca
     2821 tataagtgtt ccagtaagta acagcataaa aaagcgagat agtagcaata gacggtaacg
     2881 ctaatggcag cataattttg aaaaatacac caaaatctgt gcaaccatcc atttttgctg
     2941 attcttccaa actatccggc aaggcttgga aaaagtttct cataatgatc atattcattg
     3001 cattaacagc cacaggcagg atcatggccc agtaagaatt gaccagccct agagaacgaa
     3061 caactaagaa cgttggaatc atccccccgc tgaacaacat agaaaataca acaagaaagt
     3121 tgacgaaacc tcgaccaaac aaatactttc tggaaagacc gtaggccatc agtgaagttg
     3181 cacacatact gacgatcgtt ccgacacctg taacaccaat cgaaacagca agtgctctaa
     3241 aaatggtcgg cgtagaaaga atgtagcgat acgcgtctaa agaaaaggta gtaggaaaaa
     3301 ggataaactt tttcgcgacg acttcttgtg tagaagcaaa agatgtagcg atgatattta
     3361 aaaaaggaac gatacagatc aaagctagca aaattagaaa cgtattgttg aaaagtgtaa
     3421 aacttctttc tcctatagag actttctttt tcatatagat aggctcctcc tcaaaataaa
     3481 ttaaatgttt ctgtttctat atgttcaatt tatcatcggt gaaagattac gtatataatc
     3541 atttcctatg ctaagtgtca gatagaaaaa aatagaaggt ttgctatgcg tagtttattt
     3601 gtgaaaaaat acactttatc gttttgtata gcacaaaaat cattgctatg taagcgtttt
     3661 tacttacggt aaaaatgatt atatacgtaa ttcagatagt tatctatcat gaagtcataa
     3721 gcagcaaaca ttcacaaaac taaggagggg cttatggaaa gtgtaaagaa acaagaacca
     3781 tttcaactga cgctatcgaa aaaagaagaa aagctcagaa gacgaaaaaa aataattgca
     3841 ggaatcaaaa cgaataaatt tttatatgtg atgattctgc cgggagtcct ttatttcttg
     3901 atttttaggt atcttcctat ggggggactc gttattgctt ttcaagatta tcaaccattt
     3961 ttaggaataa tgggaagtcc ttgggtcggt ttcaaacatt tcattcgttt gtttacagaa
     4021 ccgacattct ttacattatt aagaaatacg ttgatcttgt tcggattaaa tatcttcgtg
     4081 ttttttccga tgccaatcat tttgtcttta ctattaaatg aagtaacgaa caaacgattg
     4141 aaaaacggga ttcaaacgat catttacatc cctcacttca tgtcttgggt aatcattgtt
     4201 tcgattactt atgtattttt gaatgttgac ggaggggtat tgaatgaatt ccttgcaaca
     4261 atgggatttg aaaaaatcag ttttctaaca tcccctgaat ggacacgcac agtatatatc
     4321 ggacaagtga tctggaaaga gttgggctgg tctacgatca tctacctttc agcgataact
     4381 gcagtcgata cacagttgta tgaagctgca gaaatggatg gagcaggacg cttacgcaaa
     4441 acatggcatg ttacattgcc ggcaattcgt ccagtaatca ttaccttgct gattctaaaa
     4501 atcggtcaga cattagactt agggttcgag catatgtact tgttattgaa ttcattgaat
     4561 cgaagcgttg cagaaatttt cgacacctat atttatacag ctggattgaa gaatggacag
     4621 ttaagtttca gtacagcaat gggattgttt aaaggggtcg taggattgtt tatggtaatt
     4681 ttagctaata agattgccaa aaagctagga gaagacggcg tttactaaga tagaaagaga
     4741 gggaaagata tgctgcagtc attagataaa ataaacggaa ggctaaatcg tattttacag
     4801 ttggtttatt tgaattttct gtggggcggt ttagtcatcg caggtttggg agtttttact
     4861 ttcggtcctg catcgtatgc gatggttgca gtgattagaa aatggctgcg ctcaaaagaa
     4921 acgtttcctt tgacgaaaac gtacttcaca tattttaaag aaaactatcg tgaaaccttg
     4981 ctgatgagct ggatatatgg cgccatcggg attgttttac ttgtggatct ttctttcata
     5041 cacaattggt atcttaggat cgctttgtat attgctgcgt tcatatatgt gctctcagca
     5101 ctctatattt tcccaatcat ggctcattat gattggaaag gatatttttt caaaatgaaa
     5161 atggcatttt tattcggatt ctcacatctt cattactcat tagtgttgat attaagtatg
     5221 gtagggattt atctgatgat catccaaaca atgccaggtg ttttaacctt tatcggtggc
     5281 agtctcttct tttccgcagt cacgtggaca gcaaattcta tattttgcca tttggaatgg
     5341 aagaactcat atacagaaaa aacagaagaa aacaaaaata ttattaaaac agtgaaggag
     5401 aaaatttatg aaaaaagcaa cgctcgtaaa attaggtctt agttttgcag gaattctagc
     5461 acttgccgca tgcggcagca gttcaagtaa cagttcttca gagacagaag atggaaaagc
     5521 taaaatcact tggttaaata ttttgcatca tgcttcaccg cctacagaca cgattgtgaa
     5581 cttgatcgaa gaaaaaaccg atacggaact gacattcaac tggattcctg atgcttcaaa
     5641 agaagaaaga ttaacaactg cattggcttc tgatgaacta ggagatatcg ttacacttca
     5701 aattgcgatg ttgaaaaact cttctgtccg caatgcgtta aaatcaggcg tattctggga
     5761 tgtatcagaa tatttaaaag actataaaaa tttaagtcaa atttctgaag atagaatcga
     5821 agctgcgagt atcgacggtg ccttgtacgg cgtaccgata caaaaagact acgctcgtgc
     5881 tggcttagtc attcgaaaag actggttgga taatctagga ctagatgttc caactaccat
     5941 ggatgagctt tatgaagtag ctaaacaatt tacagaaaac gatcctgatg gaaatggtgt
     6001 ggacgacaca gttggttttg gcgatcgtgc gcctagtgat attcgttata ccagctttaa
     6061 acttttcact tcttattttg gagcaccaaa tggctgggct gtagacgata atggcaaatt
     6121 cactccagaa tttgatacag aagagtatat gaaagctttg aatttttcaa gagatctatt
     6181 tgagaatggc tatttggcac aagactttgc agttacccaa aagactgatc agcaagaaca
     6241 atttgcacaa ggaagaactg gaatctacac tggaatggtg gatatcaaga atctgaagac
     6301 gatgggtcaa ggtattcaag atgatatgga attagtgcct gtaaacaaga tctcagatgg
     6361 tgaaggcggc ggttatcatg tttggtcaga aggaaatggt attggcggct tgctagcatt
     6421 tcccaaatct caagtaaaag acgaagcaca attgaagaaa ttacttcaat ttgttgatga
     6481 tcttttagaa gaagatgtgt ataaattgat gactggcggt atcgaaggaa cgcattatga
     6541 attgaatgat gatggttcta tcgaatttat cgatatggat ctttggcaac aagaggtgca
     6601 accgttatca agctctcgtc ctagtgaagt gacgttctct ttcaaagata cagaccctga
     6661 aaaagaattc tctaatcaat tgatcaaaga aaatgaagaa tttgctgtaa tggatccttc
     6721 tgtgccattg gattcaccga cgaacaatga agtaggatca gaaattgaaa aaatcgtcat
     6781 tgatgctacg gtgcaataca tcatgggaca gcttgacgaa gatggattca aaaaagctgt
     6841 agaagactgg aaagcacaag gaggcgatcg aatcacacaa gagtacgagg aagcatacaa
     6901 agcagcggca cagtaatata gacgattggg acaaatactt cttggtattt gtcccaaatc
     6961 ctattttaat ttttaaagga gagcaaataa tggaaaactg gtcaaagaaa ttagcaaaaa
     7021 gtatcatgga aagaacacct cgcttatatg aagaaaagtg gtataaagga aaatggtctt
     7081 atgactatgg cgtcgtactt aaagggttcc aattactttg ggaacgaacc caagaaaaaa
     7141 tttattttga tttcataaaa gacaatatcg actatttcgt gcaagaagat ggaacgatcc
     7201 gtggctacag cgttgaagaa tacaatatcg accatgtaaa tacaggaaag cttttctttt
     7261 tattgtacaa agaaacaggc gaagaaaaat ataaaaaagc agcagaactc ctttcccagc
     7321 agttggcaaa ccatccacgc acatccgaag gagctttttg gcataaagaa atttatcctt
     7381 atcaaatttg
//
LOCUS       DAZAOD010000114         7388 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000114 DAZAOD010000000
VERSION     DAZAOD010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.116"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(29..1261)
                     /locus_tag="ACHDPO_002530"
     CDS             complement(29..1261)
                     /locus_tag="ACHDPO_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFN3370115.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="ACHDPO_002531"
     CDS             1516..2085
                     /locus_tag="ACHDPO_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3370116.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="ACHDPO_002532"
     CDS             complement(2263..2703)
                     /locus_tag="ACHDPO_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFN3370117.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="ACHDPO_002533"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="ACHDPO_002533"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFN3370118.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="ACHDPO_002534"
     CDS             3657..4580
                     /locus_tag="ACHDPO_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFN3370119.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="ACHDPO_002535"
     CDS             complement(4805..5044)
                     /locus_tag="ACHDPO_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370120.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="ACHDPO_002536"
     CDS             complement(5049..5468)
                     /locus_tag="ACHDPO_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFN3370121.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /gene="mef(H)"
                     /locus_tag="ACHDPO_002537"
                     /gene_synonym="mefH"
     CDS             complement(5695..6933)
                     /gene="mef(H)"
                     /locus_tag="ACHDPO_002537"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFN3370122.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..>7388)
                     /locus_tag="ACHDPO_002538"
     CDS             complement(7040..>7388)
                     /locus_tag="ACHDPO_002538"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370123.1"
                     /translation="NSNQSVLLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQG
                     IKDKSLEIENSHEIAEVIMVLSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLL
                     DEETISAFIQFCK"
BASE COUNT         2377 a         1366 c         1298 g         2347 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattg
//
LOCUS       DAZAOD010000115         7247 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000115 DAZAOD010000000
VERSION     DAZAOD010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.117"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(363..1998)
                     /locus_tag="ACHDPO_002539"
                     /pseudo
     CDS             complement(363..1998)
                     /locus_tag="ACHDPO_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2437..3306)
                     /gene="scrK"
                     /locus_tag="ACHDPO_002540"
     CDS             complement(2437..3306)
                     /gene="scrK"
                     /locus_tag="ACHDPO_002540"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFN3370124.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(3326..4447)
                     /locus_tag="ACHDPO_002541"
     CDS             complement(3326..4447)
                     /locus_tag="ACHDPO_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFN3370125.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(4449..4844)
                     /locus_tag="ACHDPO_002542"
     CDS             complement(4449..4844)
                     /locus_tag="ACHDPO_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3370126.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(4863..5660)
                     /locus_tag="ACHDPO_002543"
     CDS             complement(4863..5660)
                     /locus_tag="ACHDPO_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFN3370127.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(5662..6450)
                     /locus_tag="ACHDPO_002544"
     CDS             complement(5662..6450)
                     /locus_tag="ACHDPO_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFN3370128.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(6464..6940)
                     /locus_tag="ACHDPO_002545"
     CDS             complement(6464..6940)
                     /locus_tag="ACHDPO_002545"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3370129.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(7012..>7247)
                     /locus_tag="ACHDPO_002546"
     CDS             complement(7012..>7247)
                     /locus_tag="ACHDPO_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFN3370130.1"
                     /translation="SFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQ
                     THFKQSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
BASE COUNT         2339 a         1491 c         1072 g         2345 t
ORIGIN      
        1 tctcagaaac aaaccactca ttggaaaaga catgaatcaa atcatcactt acttgtgtaa
       61 aatagcgacg tttaatgaca aagatatctt cattgctatc tagtgtacct tcatttcttt
      121 gtgcttaaat tcaaagataa ttttctcaat aaagattttt gattccagta agattccttt
      181 actcctttta caacatagcg ttgtcctttg ttttgaaaca tcttcttccc ctctttgcca
      241 ttaaaaatag cccaattctc tataaagaag attaagcttc attattataa tataaagttt
      301 aaatttggtt tattacttac tttttcttat tctctagtaa gctaatattg aaaaaaatgt
      361 aatcagatca ttatttttat atgttgtaac ttcctgataa gaaaactaat taaaagaaag
      421 aggtaactac ataaactaat taaaaaagct aacttcatag ttggaggata aatggaagaa
      481 acttcaatga ttgtttctcc ttgtgttcct tcaatcgaca ctagtcctat tatcaatctc
      541 tcttttttgt ccatttactt ttgcgactgt tccccaataa tcaaatacag gaagcgttat
      601 tttttgtcct ttagattcat gtactgtata gactattttc gaatccatca cttgataagg
      661 catagtatgc cattccttgc caattcttac ttcatgattc tgcaaatgtt ctttgtattg
      721 taatgcttcc gtgggtgcat agtcataaag tcctccggga aggagtgtcg tgtaacgaat
      781 aagattttct tgattcatta ccaagtgatc tctctgagtg acaactttat gttcatagtt
      841 tgcttttgtt gcagcagata cagccaacag taataaaaca attgccgtta tattaactac
      901 ttttctttgc ttagctgatg tgctcttcat gaaaacgaac gataaaatca acgagccaaa
      961 cagtacttga aagcctaaga ttcgccaagg aaattgaatc atttgaatgg gtgtattttg
     1021 taataaagac catggaaaaa atttggtgga taagagccaa gagactaccg cactaaggta
     1081 aatcactttt tctttgcgat taaatccttt aaaaaagaag agtggacaga tcaaagaaat
     1141 aataccaatg attcctaccg taaaggttgt caggtcatta ttcatcgcac caatcaaact
     1201 atccgagaca tttaatgctt ggtgttgtaa ggtcgtttta tctggctcat taatcgattg
     1261 aaccatgatt tgtcggaaca tcggatacca aaagtatgct gttaaaagaa tcgtcattcc
     1321 tactgccttt gacaactcca caatcaaccg gatgctttct ttttttcttg tttcacttac
     1381 tacaaagccg cctaagacta gtaagccaac ggctattaca ctcataaaag tggaaagaac
     1441 atgtgtataa atgagtaagc tcatactgac tgctaatgga attgcacatg gctttttctc
     1501 ataaatcagt gcgtaagcat aatacataac tatcggtata accgtaagtg caatcgcttc
     1561 agcaatagca gaacgatgat aaatatcaat cgtacggtac ccataaaatg tatataaaca
     1621 gctaaatata aaagccgcat cgattctttt taaaaatttt agtccataat gaaacatcag
     1681 catgatagta caaacattca atagccaaac atataagata taactaacga ttaaattatt
     1741 acttatccaa taaaaaatga ctgccggaaa aaaggtcaag tagggataaa aataattcac
     1801 tccgctccca taatgattaa acgtcgtaaa attgattgga ccagaaaaaa ttgaagataa
     1861 ccctttgact ctagcaaaat ggaaggcaat atcccccgat gtagaaatag tatgaacatt
     1921 tctaaaataa ttgattgaat aaagtccagc aataattgct aggagaatgg acaatattat
     1981 ttttttcttt acttgcatta cttaattata tactcctttc atggattgct ttatctagta
     2041 taacttaaat tttaaataaa tcgttattta tttttactct cacttaaaaa agcactaaaa
     2101 ttataagaga gggaggtaat ggtctgaaca ccaagaattg ttccaacatc gaattgctta
     2161 actaatgagt tcaaagctta attatgtggc tcttatattt accgagcgtg gattgcgatc
     2221 tctttagcga aacaaacatc tttcataaaa aaaacagcca tatccgcttt cttggatatg
     2281 actatttact actactttac tatctttcat tcttcttgtc tcacttatga taaggcgctg
     2341 ggtatcatga gtgaatgata ttgctgaata caaatagtcc gaccacatta agttgatcgg
     2401 acttcataag cattttattg actaatactt ttttgcttaa gaattgattc taacatcttt
     2461 tgctaaagtt aagcatccta tagttcctgc attatctgct aacttaggtg tgacaatgta
     2521 ttcttcgata tttggcgtat cgacatagcc gttaattagt tctaaaaaac gtctttgtac
     2581 tttctttttc agatgttctt gttgcatgac accaccacca aaaattataa tatctggtga
     2641 aagcatcagg gtcgtattac aggcacattg tgcaatataa tccgcctcga tttcccagaa
     2701 cggatcttct atagaaagat cttgtccctt ggttcccgta cgcatctcga tagcgggtcc
     2761 agatgccaac ccttcgagac aatcatgatg aaaaggacaa gtaccagaga aagtatctcc
     2821 tgaatgtctc ttaactaacg tatgccccat ttctggatgg ctaaaccctt caacaaaaat
     2881 cccatcttgt atagctcctc caccaattcc agttccaaca gtgtaataaa caacactgga
     2941 taaacctttt ccatgacctg aaacatactc cccgtaacaa gcagcattca catcggttgt
     3001 ccaggcaatt ggaatttcga aatgcttatt caacgttcca acaaaatcaa aatttttcca
     3061 ggcagttttt ggagtagagg tgatatgtcc ataggtcttt gattcacgat ggatatcaat
     3121 cggtccaaat gaccctactc caatgctttc taattgttct ttatagtgat taaagaaatc
     3181 aattaccaaa ctcattgttt cattcggtgt agttgtagga aaactcactc tttctaaaac
     3241 ctttaaatca tcattgccaa tggcacaaac aaatttagtc ccacctgctt ctattgagcc
     3301 atacatttct tactccaccg tccttttatc taggaattcg ttcttccctg tctaatagtt
     3361 tttcgaaaaa ctcatgtggt tccttttggt accaataggc aacagaagaa atatcgtctt
     3421 gacgctcata aagcttgatg tcatcatttc ctagggtttg gaaagtaaca cgtaaatttt
     3481 ctttgaaact aatggggtcg ggtaaatgcc agcggtacaa cccatgcatc ggtaaagcat
     3541 catcgccaaa accatgaact ggatttggat taggttttcc agcactaaaa taatcccggg
     3601 tgtgatctct tttagattga aaaggatagc ccataaatag cgtattaaaa ttttgagcat
     3661 atgccctttc tccaaagttc tttttatgga aagcccaagc gccgccaaaa taatcttctg
     3721 ctcctgtaga tgttattgta gggaaatctt catctccatc tatataaaac ttaaattctc
     3781 cttcccccca ccagtatctt tccaatgcgc acaaagcaaa gtaggttcct acataatacc
     3841 cagtgccttt gattccatca ataagggtgt aatcttttcc ttttgtcgtg atgggttcac
     3901 ggttccattt agcatgaaaa tacatcgcat catccggtac ttcagtcaat gcataattaa
     3961 atgtataaaa aatgtgctta ataaactcag gatgttcatt cgttaaagta atcttagctt
     4021 tttttcgaaa tggcatctca aaatagcaat tcatccctga tgttggattc actacgattg
     4081 gtaaggaatt cacttcgcat cttgtcccaa acccattaca aaaaaaatct cctaatggac
     4141 tttctacaga aggagtggat tcatcatccc aataaatacg caaaattaaa tcacgtaaga
     4201 cgaaactccc agcgattgtt ttgtctgtca ctgtcatcca aaaatgacgt aaaattccag
     4261 ggccttccat ttctgctaaa gtaattgtct ctccagcatt tatcggaaca gaaggtgacc
     4321 cttttctccc aattcctaga tgactcgctg tcattgccgc tttccctttt tcaccatttt
     4381 tattttctgg tgaaatagtt ctactttcct ctcccttgtg gagccatata ttatttaaac
     4441 aattcatttt attcgtcctc tatcctttct tcactttttt gattattcat atagatgatt
     4501 tgttgttgtg cctccgcaat aattgctcca atatctaaat tatcatttcc taactgcaaa
     4561 gcgattgaca ttgccaaggg aagattcatt cctgcaatta cgtgcactct gtcagaaata
     4621 taggtaaaaa acttttgatt tacacttcct ccagccatgt cagttaaaac aattatttcg
     4681 tctgtagtat ccactaactc tttaatttgt tcatctatat catcaatttc ttcgacatat
     4741 gcacataagc tactaatttg attatgcata cctgttaaaa actctagtgt ctctttaaaa
     4801 ccctcagcta gtattgaatg gctagcaatg atcaatcttc tcataattca aatccttttc
     4861 ctttacgcta atattccaaa tgcagccata accatcgcaa aaacaataac gagtagaatc
     4921 aaaatggtca tactgatttt tttcttactg agtagataat atgctgcagc agtaataatt
     4981 actggaatta atgttggtaa aattttgtcc aacattggtt ggattttcat actaacttca
     5041 ccaaaagtga atttaagtgg cgttgaaaca ctgataactg aagcaattaa tgatccaact
     5101 actgttagcc ccaatactga agcagcttca gttaaataat taatcttttc accgtattca
     5161 gtaacaatct tcattccctg cttataacca aattcaaagc ctctcattcg gaaaaagaag
     5221 attaccatga ttaaaatgaa ccataaaaag attcctacag gattattttc taaagccata
     5281 taagccgcaa ttgatcccat gatggttggg atcatcgtca tcaaaagaga gtccccaata
     5341 ccagcaattg gacccatcgt accaacttta aagtcattaa tcgcatcttt tgcttctaat
     5401 ccttgctttt cctccattgc aacacaagca cctaaaataa tggctgccag ccaaggctgt
     5461 gtattgtaat actgaaagtg attatttaaa gcttcgatgt attcatcatc atctttgtat
     5521 aattttctta aaataggtga caatgcgtaa gtcacagatg caccttgctg tgtttgataa
     5581 ttaaaggtac aaactgacat caaccaacga tagttcgctt tcctaagatc ctttttcgtt
     5641 acttgatatt tttcgctcat tttattcatc ctccccaata aacccaacat cagaagctcc
     5701 cgcagaagca gtgatttgtg catctttttc agctctatga tacacattaa atgctaaagc
     5761 gaatcctatg atcgccgctc caataatagg taccttcaaa aaagcggcta agaaaaatcc
     5821 aacaagtaaa taactaatgt atcgacctgt aggcataaag cgtaacaaca tcgcaatacc
     5881 aacagcaggc aacatttttc cggctaatgt tagcccatcc ataaaccaat taggtaaaac
     5941 atccaaaacg taattaacag cagactgtcc taaagtaacg gcaataaata ctggaattgc
     6001 tgcagataaa ccaaagaaaa ttggccccaa ccacaaaaca ctattcattt tcttaaattc
     6061 tcgtttattc gcatattcct gtgatttgcg aacaacaaaa ccatttaaga ttttgacaat
     6121 tacatctagt tgcaccccta acatacctac aggtagtcct attgctaatc cggcttctac
     6181 tccaagctgg ctaccaaatg ccgttgcaat aattgcgcac gttccatagt ccggtacaga
     6241 tgagccacca aaaccggcaa ctcctaatga catcaattga actgtaccgc caactatcaa
     6301 acctgttttt atatcaccca tcaaaattcc tgtgaataat ccccaaaaaa ctgcgtaatt
     6361 tacaaagatc atcggaatcc cataataatc aacatgttta ataaatgcta atatagtcag
     6421 cataataatt tgaaaaatag taaaatgcat tatccttact cctttatcct aattttgatt
     6481 gaatttcctg tgccttatcc gccggaacaa attgtgtaac aatttctaca ccagaatcca
     6541 acaatttttt atacgtgctg atattttcat ctgatgcata ggctctagaa gatagctgta
     6601 atgcattatc tttaacaaca gtaccgccaa caattagtcg gtcaattcta ataccgttat
     6661 ctactaaatg aaggattgtt tccggctctt tcacgatgac aaatactttt tcctgatcgt
     6721 atttcccctt tttaaaattc gcaatcgctg tttcttcagt gataattgat acagccattc
     6781 cagcaggtct agctaaacgc atacttgatt tttggatgtc gttatttgcg acagaatcat
     6841 cgatcaccat cactctgttt gctttagaca ttggtgccca ttgcgtgaca ataatcccat
     6901 gcaataaacg gttatcaact ctcgacataa caatactcat aaatacttcc tcctttatct
     6961 ttcattttct tacaagcaat taccatgcca aaacaaaaag aacttgataa atcaagctct
     7021 ttttacataa tcataaacgt atttaacctc atgaatcggg atgtcgacac tataataatg
     7081 ttcaacgaca ctgaaagatt gcttaaaatg tgtctgaaat ttttgaaatt cctcactcgt
     7141 ttcattgaaa taaatttcat cttccaaagt attttgtttt actaatcgtt caattaagca
     7201 actaatgtga acatataatc cgaaacacgt attattatca aatgaaa
//
LOCUS       DAZAOD010000116         7141 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000116 DAZAOD010000000
VERSION     DAZAOD010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.118"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..615
                     /locus_tag="ACHDPO_002547"
     CDS             <1..615
                     /locus_tag="ACHDPO_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFN3370131.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            612..1385
                     /locus_tag="ACHDPO_002548"
     CDS             612..1385
                     /locus_tag="ACHDPO_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFN3370132.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1382..1780
                     /locus_tag="ACHDPO_002549"
     CDS             1382..1780
                     /locus_tag="ACHDPO_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFN3370133.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1965..2636
                     /locus_tag="ACHDPO_002550"
     CDS             1965..2636
                     /locus_tag="ACHDPO_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370134.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2695..3135
                     /locus_tag="ACHDPO_002551"
     CDS             2695..3135
                     /locus_tag="ACHDPO_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370135.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3147..3815
                     /locus_tag="ACHDPO_002552"
     CDS             3147..3815
                     /locus_tag="ACHDPO_002552"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFN3370136.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3879..4502
                     /locus_tag="ACHDPO_002553"
     CDS             3879..4502
                     /locus_tag="ACHDPO_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFN3370137.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4558..4944
                     /locus_tag="ACHDPO_002554"
     CDS             4558..4944
                     /locus_tag="ACHDPO_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFN3370138.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5157..6548
                     /locus_tag="ACHDPO_002555"
     CDS             5157..6548
                     /locus_tag="ACHDPO_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFN3370139.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         2277 a         1160 c         1572 g         2132 t
ORIGIN      
        1 tttgtttttg caccgttaga aggagaagac ctcgcttcat ttctggttgg tgcggcaatc
       61 atgatgatcg gaatgacgct ctttttgttt ggagcagatt attctatgat ggaagtcgga
      121 gatctagtag ggaaatatat gatcaaaaag aaaagtttga ccgttttggt cagtttggga
      181 tttgctatcg ggatcgtgat cacgattgct gaaccttccg tgcaagtttt gggacaacaa
      241 gtatatgata tatctgacgg agagattggc agagtgttgc tgattgggat cgtcagcgtc
      301 ggcactggag tatttctagc ctttgcgctg cttcgggtcg tattcaagct atcctattat
      361 caattgatgg ctataggcta cataggcgtt ttgatcgcct catttttcac cagttccgaa
      421 tttatgccga ttgcttttga ttcgggggga gtgactactg gtccagtaac tgttccattt
      481 atcttggccc ttgccggagg gatgactagt atgatcaaac aaaagaaaaa tgaaaatgac
      541 agttttggaa tggtcggtat tgcttcgtta gggccgattc ttgccgtgat gattttgggg
      601 gtgatcttcc aatgagtttc tggcagcaag tgatagatgg aatcgaaatc gttaccatgg
      661 aagtcatttt ggcagtggca cctatcgtaa tcctatttgt tttaatgaat atcattagtt
      721 ttcgtatgcg caaaaagcgt ttctttgaca ttatgaaagg tttcttgata acgactattg
      781 ggttgatcct tttcctgcac ggagtcaata tggcttatgt accggtagga cagcatttag
      841 gcagtgctat tgcgggattg ccttacaatt atatactggt tccccttggc tttttaatgg
      901 ggttcttagt agggtttgct gagccggcga ttcatgtaat gatcaaacag gttgaagaat
      961 tgagcgaggg gagaatccga tcgaaaatca tgctgatggt aatttcaatt gggatcggcg
     1021 cagcagtagg attgtctatg tggcgtttgc tcgtcggatt ctctctttat tatttcttga
     1081 tcccaggata cgggctagca tttattttag gacgaaaagt ggacaagatc tttttagcaa
     1141 tggcttttga taacggtgga gtagcaacgg gcccgatgtg ttcgacattt attttatcaa
     1201 tgagcgtggc aatcgctgca caaattgaag gaagagatcc gatcattgac gggtttggtg
     1261 tggttgcaat gattgcattg acaccaatat tatccacttt agtactagga tatatttata
     1321 aacgaaaaga tgaaaaagac agaatcgaaa aagaaagatt gcaaaaattg ggggaaagca
     1381 aatgaaagat cttgtagcat tgaatcttca catgattgtg acgatcgttg acggaggaat
     1441 gggcgaagat gttatcgact tttcaaaaga agcaggtgca gcaggcggaa cgatcttaca
     1501 tggaagaggt tctggtgtac atgattcagg gaaattttta ggtttggaca tttcgccaga
     1561 aaaagatatt gtgttgacat tagtacccga tagtttgacg aataaagtaa tggatgcgat
     1621 tggtcaaggc atcaacatcg atattccagg taatggtatt tgttttagta ttgatgtaga
     1681 caaagtcatt ggtatcacta agattcatca atatcgagaa attatcggaa tgcaagaact
     1741 tttagatgaa aataacgata gagaaaagtc tgaatcatag acaagcgttt gaagaggaaa
     1801 taaacacaaa caagaaggcg gatgagcgtt atttccgctt ttttgtttgt atttttctcg
     1861 tgaatactta tgaaatagta aatttttatg aaattctact ctaagcatca gactttcttt
     1921 tcaaaatatg ctattttaaa aatgatgaaa aaagggggag aaaaatgaat tttttagttg
     1981 ttttaaaaga tactctgatt gagcgattta catttctata tgttcaattg caggaaaata
     2041 aaacattgct gcatttttca ccagagttcc atctagaggg gctaacatta ggagaaatct
     2101 atcaagcaga agggctgtcg gctgttttgc acttttttaa ggtagaattg gaattaccag
     2161 taaaagatta tatcgagctt tctcttgaat cttgggatcg agcagtggtt gaactgtttc
     2221 cagaaggttt aatgatcgat acaaacgatg ggaagatcca tctgactgca gcagaactgc
     2281 aaaaacaaat gcgttatcaa atagatgacg aaaattcttt ttctattttt agacgtcagc
     2341 aaaagattct aaaaagcttt ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga
     2401 cacagctgtt gaaaaaatat ccaggtctgc ttcacacgtc tattcaattt cctcaattga
     2461 ttacgatgat ccatcgtttt atacgtatgc aacagctacc atctaagaag ctgtttcttc
     2521 cattgacgga cacatttcga gtagtcaaca gagaagataa aaagaaagtg attgtgattg
     2581 actttaccag aaatcggaat gtccttcacc aagttgcaat ggaaaaggcc aattaaggct
     2641 ttttcttttt ggattttttt gtcataataa atattagatg atggaggaga taatatgatg
     2701 caaacatggt tagaaaggct aatacgattt cagcagaact atcacaaact tatgcaggga
     2761 agatatgcga aatttgatca gttgaatcgc ggtctattga tcgctgcgct tgtctttagt
     2821 ttgctaagtc gttggttgcc ctatagaatc ggacaattgt tgttcatcgt ctttttcgga
     2881 tggatgatat ttcgtttcct atcaaaaaaa atctacccca gactaaatga gaatcaacgt
     2941 tatttgaaat atcttgatag agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa
     3001 gtcaaaatgg atcgaaaaag ttatactttt tttgagtgcc cgaattgtca tcaaaagcag
     3061 cgtgcaccta aaggaaaagg acgaatacgt gtgacatgca aaacatgtgg tataaaattc
     3121 gaaacgaatg tttaagggag aaaagaatga aattagtatt attacgtcat ggcgaaagcg
     3181 aagcaaattt tgaaaattac tggacaggat ggctagatgt cgccttaaca gaaaaaggaa
     3241 aagaacaagc agcagttgcc ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg
     3301 tttatacctc tgttttgaaa cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg
     3361 gtcagttatg gcttcctata ataaaaacat ggcgtctaaa tgaacggcat tatggggatc
     3421 ttgtgggtaa aaacaaagat aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat
     3481 ggcgcagagg atatacggaa gttccgccgt taaccgcaga aaatagattt gaccgcagat
     3541 atgatcactt ggatccgcat ttgatcccat acggagaaag tctggaaatg acagtgaatc
     3601 ggatcattcc cttatggcaa gatcatctag caccaaaact aaaagatcgg caagatttac
     3661 tagttgtggg tcatggtaat agcatccgag cactgacaaa atatttagaa gatgttcctg
     3721 aagatcaaat ggatacgatc gatatcccaa atgcacaacc aatccagtat acattagcag
     3781 atgatttgac aattctggac aaaaaaatac tttaaagaac acctttatct aaaagtgaga
     3841 gatagaaaaa agaagcaaag gaatggaaca aaaggaacat gaaaaattat atatgggact
     3901 ttgatggtac attgtttgat acgtatcccg caatggtaga tggtgcatgg caagcactaa
     3961 aagattttgg tatcagtatg gacaaaaaag aaatctactt caaaatgaaa aagtattcta
     4021 ctagttattt gatcaatgaa tcaaacttga atgccagaga gtttaatgaa ttatttcacc
     4081 gatatgaaaa agaaagtacg gaagtttccc gtccatttcc agaaacgaaa caagtactgg
     4141 aaatgctaaa agacaacggc ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa
     4201 catggggcct gttaaaagaa catcgattgg cacatctgat tgaggaagta gtagggatcg
     4261 atcaggactt tcctcgtaaa cctgatccag catctttaaa ttatttgatc gatacttttc
     4321 atttagaaag aacagacacg atgatgatcg gcgatcgtcg tttagatatc gaagcaggga
     4381 aaaatgcagg agtcgctact tgtctttacg acatcgatca ttttctgggt gagatcccgg
     4441 cagattatgt ggtaggaaat ctgaatgaaa tccttacctt gcagagcatc attaaaaagt
     4501 agtatcccct ttcaaaggag atatgttata attttcataa aggagtgata aaattatatg
     4561 gaaatcagaa gacaaaaaga agttgtagaa gcatttcatt atgatatgag attgccgaac
     4621 caagaagtag aaacagattt gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac
     4681 tatccgaaag aacatagcat cgtaggagca cgcttagagt tccgtttagt gtttgataca
     4741 tatgttttat ctggaagtgt gagtcagatc aatcatatcc tcaatcggaa aattgaaggt
     4801 caaaatgatg tcacacaaga agaagtggac gagctagtag caccgttatt cgatatcgta
     4861 cgccgaatgt cttatgaggt gacagagatc gccttagatc agcctggggt aaaattgaat
     4921 tttcaatcag aaaaacaaga atagacagta aaaacatacc tgcgatagat taaagctatc
     4981 acaggtatgt ttttttatta ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg
     5041 tctaaaatat aaaagtcact gaaaaaaatt ttttcaggag gatggttgaa gaatcattct
     5101 cgggaacctt tacttccttc gatggacttg tcattaataa tatgaggagg agaaaaatga
     5161 caacactcat cacagtttta gtggttctag tttttgcggc attattatat gtgttctatc
     5221 gtatgcaaaa gcgccataca aaattttcaa cacgcgtctt tacagcatta ggagttggta
     5281 tcgtctttgg cggtctgctt caattgatct ttggtgtaga cgacaaagtc gttactcaat
     5341 caatggaatg gatcgggatt gtaggtcaag gatatgtatc attcttgcaa atgctagtta
     5401 tgcctttagt gtttatttcg atcattggtg cattcacaaa aatgaaagtt tctgaaaagc
     5461 tagggaaaat tagtgcgact gtattgactt ctttacttgg aacaacagct attgcagcat
     5521 tgatcggaat tggttcaaca atgctgttcg gactccaagg agctaaattc acacaaggag
     5581 ctgcagaaac agcacgaatc tctgaactgg caacacgtca ggaaacagtt gaaaacttat
     5641 cgattccaca gcagatttta tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta
     5701 gtcgtgcaac aagtacgatt ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc
     5761 taggcgtgaa aagaaaagcg ccaaaagaag cagcattctt ttcagattta gtcgacagtc
     5821 tgtataaaat cattatgcgg atcgtgacgc ttgttttgcg tttgacacct tatggagtat
     5881 ttgctttgat gacaaacgtt ttggcaacaa gtgattttgc agctatcgtc aatttaggta
     5941 aatttgtcgt tgcttcttac gtagcattgc ttgctgtttt gattgtccac tcactgattt
     6001 tgattggtgc aaaagtcaat ccaatcaact atttcaaaaa agcctttccg gtattgagct
     6061 ttgcgtttac ttcacgttca agtgctggag ctttgccatt gaatatcgag actcagacaa
     6121 aagctttagg agtagatgat gcaacagcta atttctcagc aagttttggt ttgtctattg
     6181 gacaaaacgg ctgtgctggc gtttatccag ctatgttggc aacgatcgtc gcaccagcag
     6241 ctggagtgaa tgtctttagt ttggaattta ttttgatgct tgtggcaatt gtaacaatca
     6301 gttcttttgg tgtagctgga gtcggtgggg gcgcaacatt tgcttcactg atcgttttag
     6361 gggcaatgaa cttgccagta gcaatcgttg ggttagttat ctctgttgaa ccattaatcg
     6421 atatggcacg tacagcagta aacgtcagcg gtagcatggt agctggtatc gtgacaagtg
     6481 cacgcatcaa agatttagat cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga
     6541 atgcatagtc aaaaagaggt tgtgatagaa gtggtcagct ttaagaaata agaagaagtt
     6601 tcctaaaaat agtttctcaa atttttgtga aatttcggct tatttccgag aagctacttc
     6661 tgaaacaccg tgaataagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
     6721 caaacaaaaa tagttcctca tattttacgt ttggttgagc ttattaccgc agatgcaagc
     6781 ttttgaacac cgtttaagaa agaggtcgtg agcctgccgt ttcactctga gtcacaaaga
     6841 gcaatttcaa aaaatagctt ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt
     6901 gtcaggagaa caccgtttac cagaggttgt gacttgtttt tagtcacgac ctcttttttt
     6961 atttattcca tataaataca cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa
     7021 caaccaactt atttattatt aaagaaaagc gtatttaagt aggacgattc tgttgagagc
     7081 tttcgtagat tttcccattt tcctatggta aactgacaaa gttgagaatg ttagaacaga
     7141 t
//
LOCUS       DAZAOD010000117         7049 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000117 DAZAOD010000000
VERSION     DAZAOD010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.119"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(180..638)
                     /locus_tag="ACHDPO_002556"
     CDS             complement(180..638)
                     /locus_tag="ACHDPO_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFN3370140.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(651..1982)
                     /locus_tag="ACHDPO_002557"
     CDS             complement(651..1982)
                     /locus_tag="ACHDPO_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HFN3370141.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1993..3435)
                     /locus_tag="ACHDPO_002558"
     CDS             complement(1993..3435)
                     /locus_tag="ACHDPO_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFN3370142.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(3422..4186)
                     /locus_tag="ACHDPO_002559"
     CDS             complement(3422..4186)
                     /locus_tag="ACHDPO_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFN3370143.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4290..5165)
                     /locus_tag="ACHDPO_002560"
     CDS             complement(4290..5165)
                     /locus_tag="ACHDPO_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFN3370144.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5420..5504)
                     /locus_tag="ACHDPO_002561"
     tRNA            complement(5420..5504)
                     /locus_tag="ACHDPO_002561"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5468..5470),aa:Leu,seq:caa)
     gene            complement(5522..5593)
                     /locus_tag="ACHDPO_002562"
     tRNA            complement(5522..5593)
                     /locus_tag="ACHDPO_002562"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5559..5561),aa:Gln,seq:ttg)
     gene            complement(5603..5675)
                     /locus_tag="ACHDPO_002563"
     tRNA            complement(5603..5675)
                     /locus_tag="ACHDPO_002563"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5640..5642),aa:His,seq:gtg)
     gene            complement(5737..5821)
                     /locus_tag="ACHDPO_002564"
     tRNA            complement(5737..5821)
                     /locus_tag="ACHDPO_002564"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5785..5787),aa:Leu,seq:caa)
     gene            complement(5842..5912)
                     /locus_tag="ACHDPO_002565"
     tRNA            complement(5842..5912)
                     /locus_tag="ACHDPO_002565"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5878..5880),aa:Cys,seq:gca)
     gene            complement(5958..6029)
                     /locus_tag="ACHDPO_002566"
     tRNA            complement(5958..6029)
                     /locus_tag="ACHDPO_002566"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5995..5997),aa:Gln,seq:ttg)
     gene            complement(6041..6113)
                     /locus_tag="ACHDPO_002567"
     tRNA            complement(6041..6113)
                     /locus_tag="ACHDPO_002567"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6078..6080),aa:His,seq:gtg)
     gene            complement(6116..6189)
                     /locus_tag="ACHDPO_002568"
     tRNA            complement(6116..6189)
                     /locus_tag="ACHDPO_002568"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6155..6157),aa:Trp,seq:cca)
     gene            complement(6196..6276)
                     /locus_tag="ACHDPO_002569"
     tRNA            complement(6196..6276)
                     /locus_tag="ACHDPO_002569"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6240..6242),aa:Tyr,seq:gta)
     gene            complement(6278..6353)
                     /locus_tag="ACHDPO_002570"
     tRNA            complement(6278..6353)
                     /locus_tag="ACHDPO_002570"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6318..6320),aa:Phe,seq:gaa)
     gene            complement(6389..6461)
                     /locus_tag="ACHDPO_002571"
     tRNA            complement(6389..6461)
                     /locus_tag="ACHDPO_002571"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6426..6428),aa:Asp,seq:gtc)
     gene            complement(6471..6543)
                     /locus_tag="ACHDPO_002572"
     tRNA            complement(6471..6543)
                     /locus_tag="ACHDPO_002572"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6508..6510),aa:Val,seq:tac)
     gene            complement(6559..6630)
                     /locus_tag="ACHDPO_002573"
     tRNA            complement(6559..6630)
                     /locus_tag="ACHDPO_002573"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6595..6597),aa:Glu,seq:ttc)
     gene            complement(6645..6734)
                     /locus_tag="ACHDPO_002574"
     tRNA            complement(6645..6734)
                     /locus_tag="ACHDPO_002574"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6698..6700),aa:Ser,seq:gga)
     gene            complement(6774..6847)
                     /locus_tag="ACHDPO_002575"
     tRNA            complement(6774..6847)
                     /locus_tag="ACHDPO_002575"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6811..6813),aa:Asn,seq:gtt)
     gene            complement(6857..6972)
                     /gene="rrf"
                     /locus_tag="ACHDPO_002576"
     rRNA            complement(6857..6972)
                     /gene="rrf"
                     /locus_tag="ACHDPO_002576"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         2127 a         1554 c         1151 g         2217 t
ORIGIN      
        1 aatcaaattt atttttaaga atcctgaaaa taagttttct aaatcatagg agcaacaaaa
       61 aaattcgata attaacaaaa atcaaaatga ttaaatctag tgattgaaac atatcatttc
      121 aaaaaaattt tgtaaattca cccataaata tcaccctatt taactttttt catcgtacac
      181 taaaattcaa aacaactatc tttaatcttt acttcttggt tttgttttaa taaatttcct
      241 tcaaaaatgc ctggagaaac tacaatgatc accgtatctt tttgtgcttg ctccaacttc
      301 ttcaaatcta taatagctaa cagtgtccct tcttttacct cctggttact ttcaacccgt
      361 atctgaaacg gacttccttc gagttcaact gtatctaaac ccatatggat cagtattttt
      421 ctgccagatt cactttcgat cgttatggca tgtcgggtag gaaatatatt atcgattatt
      481 cctttaactg gcgcatggat atatccatca tgattcgtta tagcgtatcc aactcctatc
      541 atttttgaag aaaagacctc gtcttttact gctgttaatg gaataatttg accactagct
      601 acagctttta gaatgtttct tgttttaaag aaatgcactt tttatcacct ctactttaat
      661 gctggccaat attttttgtt tactttgatc atttcatcta gtattttttt tgcgactctg
      721 gcatttggta cggtttgatt caatgtaaat gcttgtaaag ctttttgata agaaccttca
      781 aagtaagcat ctactagtaa cttctctact gcaacttgtg cctccatcaa tcctttatga
      841 aaatcactga ttggttttct tagtgtaatt ggctccacac cagttgcacc aacatatgcc
      901 ggtatttcaa caactgcatc tgaccgtaga ttcggaatcg ccccttgatt aggaacgatt
      961 agcataaagc gacgacgatc atcattcaac aaggaaatag ctatatcgac gatatattgt
     1021 ccatgctccc caaaattaaa gttcaatact tcttccacaa taccgcggcg tattttatca
     1081 gccatttctt tggtattttt ctctcgtcca tccatgacca tattagcacg tgtatactct
     1141 ttgtcagtat gctcaacgac catatcagga tataagtaat actctaagta attattcggg
     1201 atattacttg gaaaattttt cgtgatgact gacatcattt gaaaggtttt ttgccaagtt
     1261 ttatctccta tattaaaatc ggcgacttgc atttcttttg ttattagttt ttcaataatc
     1321 tctggcataa tttctcgttg caattcttta tcataaatcg atgtatacca gccaaagtgg
     1381 tttaaaccat aatacgtaac gatccaattc ttacgatcat aaccgtaatt cactgcaatc
     1441 gtttcttcaa ttgaaatagt catatcacag gcattaatca tttttacatt cggatattta
     1501 cgacgaacag cttcagaaac gatcgactct ggatttgtat aattcaaaat ccatgctttg
     1561 ggggcatagt cttgtatatg atcgacaatt tccaataaac ctttgattga gcgcatccca
     1621 taagcaaatc ctccgagtcc acacgtttct tgtcctacta atccatgttt aagtggaatc
     1681 ttttcgtcct tttctcgcat ctccaatcct ccaacacgaa tttgtgagaa aacaaaatcg
     1741 catcctgtaa aagcaagctt tggatcatcc gttgcacgaa tgcgaatatt tgaaaaacct
     1801 tttcttttca gcataaattt aacaatcaag tacatatcca tatttctttc ttcatcaata
     1861 tcatataaac gtatttcaga taatggcaac cgtttttcat tgttcaaaat ggcttgaacg
     1921 attcctggtg tatacgtact cccgcctcca gctatagtga taatctgttt tttcatcatc
     1981 atcttttcct ttctattctt ctaataattt attgaattct gccataacat aagtcacttc
     2041 taagccgatg ataatttgat aatttttttc agttggttta atgatcccgc ttatccctaa
     2101 ttgcttgatt cgctgttcct cgaccatggt gggatccact acctctaccc gtaggcgtgt
     2161 attacaacta tagacatcca ggatattggc ttttcctcca aacgcttgta gcatttttgt
     2221 tgccatatat tcataatttt tacttgctaa ccctaactct gtttcttcta aggttacttc
     2281 attgccaaac tctgccttag cttcacgtcc taatgtctga atgtttctct tattgatcaa
     2341 ataataaaaa gtaacgtaat acaaggcaaa aaagaaaatt ccgattggaa gaatcaaaat
     2401 agcattggta gcgattcgaa aattgatgag ataatcaaca atacatgctc cgaatgtaaa
     2461 accaattcgt atattgaata agtaacagac aatccctgct aaaccggcaa aaagtgcatg
     2521 gatcacgtac aacataggag aaagaaacat gaaactaaat tcaacaggct cagtgatatt
     2581 tgcaataaat gaagttcctg caccgcttcc catgattcct ttgaccatct ctttattttc
     2641 tttataagct gctttataga tagctagaca tatagctggt ataccaaaca tcattactac
     2701 aaaaaaaact gataaaaaca gtccagcctg aggatctccg ttgataaagc gtgtcatctc
     2761 tcctctgaaa acttccttgc taggagatgt atagcttcct aaatcgtaat aaatatacgt
     2821 attcaacaca tggtgcagtc caaaggggat cagcaaacga ttcaaaaaca taaatatccc
     2881 cacacctaat gctcccatat caacgagcag ttttgcaaaa ttatcaatcc caatttggat
     2941 gagcggccag ataaagccca aaaaaacagc tgcgattgtt tgtagaatca tcaccatagt
     3001 caatgggaat ttttcgcccg caaaataaga aaaaactact ggtaattttt gttctttaaa
     3061 gcgattatac gtccatgccg ctactaaacc ggaaataatt ccaccaaaaa tccccatatt
     3121 cacttctggg tccataattt ctaagccttt tttcaaggta gcaatcgcta aaaaaccagt
     3181 aagtgcaggt attcctttgt ccttattttt gacaaaaccg attgcaactc ctatagcaaa
     3241 taagatatcc aagtttccaa aaacggcatt tccagctgca ccaattactg ggatgttcag
     3301 catatcgtca gctgataaac gcatgatcaa tcccgctaat ggcatcgctg caactggaag
     3361 tagcatcgct cttccaagct tctgcacatt tgatttaaca ttcattttta ttcctcctct
     3421 attaaatatc ctcatatgtt actaactcaa tcaaaggatc atttttcact ttttgagcaa
     3481 atgctgaatg aattaaaaat tcgacttggt gggtacgagg atacacaaaa cttgaaccat
     3541 ttaacaattc ctgatccaaa tacgctgcgt gacacatgac ttcgatcgtt ttatcttctc
     3601 tcaatatcat gagtaaactt gccaaatatt cttccacact cgtattgatt tgtcgttttt
     3661 tttcatcagt ttctcctacg acatcgaaac aaggctcaaa ataatcgaca tgacgaactt
     3721 catcttttcg ttcaaagttg ctccgaaccg gcaaatcata tttttttgct aatgtaacaa
     3781 ctacctcctg attttcatcc aaagtatgag tatgatgatg actgtctaaa tgagttggta
     3841 tgatccccgc atgataaatt ttttgaatct gagcattcca ttcctgatac agttgatctt
     3901 tgtcaatgtt aaatggatgc tgataataag ataaggatct gaactctccg ctttcgataa
     3961 gagtatcgac agttttgagg agtggtttgc cacacgtcaa tgttaaatgg actcctacac
     4021 ctagcctagg catttccttt cttagtttca cagcatgctc gaaacccggc atatttgcca
     4081 tcaatgtagt tgatgtcaaa attcctcgct gataagcatc cataatccca taattcacac
     4141 catggctata gccaaaatca tccgaattaa aaatcacttt tcccatttca ttctccttct
     4201 tttttctact aaaataggcg caaccaaata atcatagtcc atttactatg tgtcatttgg
     4261 ttgcgcctat agatagttac gcccttattt taatagattc ttgctagatg aattgccaaa
     4321 tagatgattt cattttcttg aatggcaagt tgaaattgct gttcgatgat atctttaatc
     4381 tttagtgctg tacaatacgc tttgctatgt ttaaatgttt cagtaaaaaa accaatattt
     4441 tctactggcg tttcttcctg ataaatcaag cgtttaacca ggaatttgat atgaaccatt
     4501 aagcgatgat aagtcagtga ttctttatca taaacgtttg aataggattt ttctagatgg
     4561 gacaaaatcg tggtcgtcat ttctactatt tttaagctct ttaaactatt aggctctcct
     4621 agctcagcat taatgatatg catagtgatg aatcctactt catttgaccc taactcggtt
     4681 tgatatcgat gattgattcg ctcgaccact tctactgcta tatcatattc atttggataa
     4741 aggaatctca tttctggcaa cataattgct gtgacatctc tatcttctct ttttcgttga
     4801 atagcaaaat aaatatgatc tgtcaatgta atatagatat ttgaatctaa tggagaggag
     4861 atcctagctg ttatcagttc aatcacttct tccgcaaaat ccataaattc gattggaatc
     4921 tgcgagacta tctcactgaa tcgtttgatc ttttctttag aatctaatac aaataatttg
     4981 tcagcatcct caacatcaaa tggcttactc actttagcag aaaagccaat ccctttcccc
     5041 atcgcaattt tttctattcc atcgtcatcg atcaatacag cattatgatt cagctttttc
     5101 atcacataca ccgttaattc acctcctcta tatgataaaa caaaacaact tgcagactcc
     5161 ttcatacata tttttgtctc caaacaattt ttaaagacaa aaaacgacct aagaaagaac
     5221 cctttcttag gtcgtgccta attgaatagt agcaccctac ataatttaca aaaatagttt
     5281 aacacataat aaaagcgtta tcaatatctt ttttactcgt tttatgataa tacttgtatc
     5341 gaattgattt ggaggtaatt acataaaaac aaaaaaaata tagcaactct ctataagaaa
     5401 gttgctatat tgataattat accggcggcc ggggtcgaac cggcacgtcc tcaacggaca
     5461 ctggattttg agtccagcgc gtctgccaat tccgccacgc cggcaaattt aaaaataata
     5521 actggggtag ctggattcga accaacgcat gagggagtca aagtcccttg ccttaccgct
     5581 tggctatacc ccaagaataa agggcgaatg atgggaatcg aacccacgaa tgccggagcc
     5641 acaatccggt gcgttaacca cttcgccaca ttcgccatca taaaagatgt tatttaattt
     5701 ctcaataaaa aactaagatg aagacatctt agtcaatacc ggcggccggg gtcgaaccgg
     5761 cacgccctca acgggcactg gattttgagt ccagcgcgtc tgccaattcc gccacgccgg
     5821 caagttgatt tattagtact aaggcggtaa ccggatttga accggtgatg aaggttttgc
     5881 agacctctgc cttaccactt ggctataccg ccattatact attatcaatc tataaaataa
     5941 agaataaatt atagaaactg gggtagctgg attcgaacca acgcatgagg gagtcaaagt
     6001 cccttgcctt accgcttggc tataccccaa gaataaaaag ggcgaatgat gggaatcgaa
     6061 cccacgaatg ccggagccac aatccggtgc gttaaccact tcgccacatt cgccatggca
     6121 ggggcagcag gaattgaacc cacactaacg gttttggaga ccgctgttct acctttaaac
     6181 tatgccccta taaaatggag gagagtggat tcgaaccact gaaccctaag gaacggattt
     6241 acagtccgtc gcgtttagcc acttcgctac tcctccatgg tggcgcggga cagaatcgaa
     6301 ctgccgacac acggagcttc aatccgttgc tctaccaact gagctaccgc gccatatttt
     6361 aaaattatta attgaataac aagaacgacg gttccgacgg gaatcgaacc cgcgatctcc
     6421 tgcgtgacag gcaggcatgt taacccctac accacggaac cagttcatta tggaggttaa
     6481 cgggatcgaa ccgctgaccc tctgcttgta aggcagatgc tctcccagct gagctaaacc
     6541 tccaacattc aattaaaatg acccgtacgg gattcgaacc cgtgttaccg ccgtgaaagg
     6601 gcggtgtctt aaccgcttga ccaacgggcc aggtaaattt gctacggaga gtaagggatt
     6661 cgaacccttg agacagtttg gcaccatcta catgatttcc aatcatgctc cttcggcctc
     6721 tcggacaact ctccagagtg aaagaagctc aatactcttt ctcaaaatga gaactccggc
     6781 agtaggactc gaacctacga catcatgatt aacagtcatg cgctactacc aactgagcta
     6841 tgccggaata acatcagcgt ggcgacgtcc tactctcaca aggggcaacc cctcactaca
     6901 atcggcgcta agaagcttaa cttctgtgtt cggcatggtt acaggtgtat ccttctcgct
     6961 atcgccacca cactgtggtg ttatctttta ttgagtaaat tttgttcact caaaactgga
     7021 tttgaagtca cataagtttt tttccgagt
//
LOCUS       DAZAOD010000118         6905 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000118 DAZAOD010000000
VERSION     DAZAOD010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.120"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..868
                     /locus_tag="ACHDPO_002577"
     CDS             <1..868
                     /locus_tag="ACHDPO_002577"
                     /inference="COORDINATES: protein motif:HMM:NF016640.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase domain-containing protein"
                     /protein_id="HFN3370145.1"
                     /translation="NQKNNSILGMKIRNKINQLNQMKKRDNLLPAKYTLKSMTGKGPI
                     KDYSNRENRSDELRKKELTNQGTPKRIAVYSCITGNYDSIKEPDFSHPLVDYYLYTDN
                     VITSEHWNIREIPKYISELKNNILINRYIKFHPNELFTDYDFTLYVDGNVTITSDITG
                     LLNSSSKLGLSMHKHSERKSLYSEADALIAVGKGNKESIIEQISKYREEGFPDNFGLA
                     EATVILVDLNNSIAENLLDLWWREYLNSESGRDQLAFPYVLWKSGHAMKEVTTLGNNV
                     YKSAKLRIISHY"
     gene            1120..2130
                     /locus_tag="ACHDPO_002578"
     CDS             1120..2130
                     /locus_tag="ACHDPO_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase"
                     /protein_id="HFN3370146.1"
                     /translation="MKILITGGAGFIGFHLSRKLLKETENQIVAIDNLNDYYDVQLKE
                     DRLTILYDYNNFKFIRMDLLEKEKLDSLFESEGFDIVIHLAAQAGVRYSIENPYAYID
                     SNIIGFLNILEACRNFPVKHLLYASSSSVYGGNTKVPFSTEDSVDHPVSLYAATKKSN
                     ELMAHTYSHLYKIPTTGLRFFTVYGPFGRPDMAYFSFTKNILSGKEIKIFNHGKMERD
                     FTYIDDIVEGITRLINKVPEPNSDWTDIDDLSSESWAPYKIYNIGNNKPVALLEFVET
                     IEKYLGVKANKIFLDMQPGDVVRTYADIEDLEEKINFKPNITLDEGIKKFVEWYTVYY
                     LS"
     gene            2498..3922
                     /locus_tag="ACHDPO_002579"
     CDS             2498..3922
                     /locus_tag="ACHDPO_002579"
                     /inference="COORDINATES: protein motif:HMM:NF026018.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFN3370147.1"
                     /translation="MDSSSNKSHSIAKKAFIYAIGTLSSKMISVIIIPIYAVYISVAD
                     LGSFDYQNTIAQFLSPVIFGAIWEAILRMGLGKEKNIQKKVVTNSICFVIANTVILAI
                     FLPIIYRMIFPNLEYYQLFVFQLIFTPILSVFQYIVRALGESKIFVMSGIIAAGINLL
                     LLTIFVVTMGMGILGLLLSIIISNVINLIFLIFRGQIFQYFATSSFDFLFLKSMLKYS
                     IPLTLNLTFGWLIVGFSRFYIGTYIGVTENGIFSFAMKFSSIILTLTSIVSMSMIEDA
                     VITSENDDFIERFVEKNTYIFKMYIRLATLSIPIICCAYSFITNPDYKKSLVLVPILV
                     IMACFSGMTTNIGNIFAVYNKTNQLLMISVVSGLLSVVGTYLLGYSFGVIGVSFATLL
                     GTLVLFGLRYYFGRKIAYYAFDWKRISLLLVLYSAIAFVCIHRGFYFNLFLTIIFSAI
                     FVFTYKQLIITYLKKFFRIKMAKR"
     gene            4008..4436
                     /locus_tag="ACHDPO_002580"
     CDS             4008..4436
                     /locus_tag="ACHDPO_002580"
                     /inference="COORDINATES: protein motif:HMM:NF012360.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HFN3370148.1"
                     /translation="MIFGKKHSLVEVPEFGSEPYLIEIGDNFRCSFGVKFITHDGGVW
                     VLRKMSSVSESTSKIGRIKLGNNIFIGIYSIVFPGVSIGDNVIIRANTLVNKDIPNNS
                     VVAGSSCKVISTIEEHYEKNKNEFIKYRTSMILKQKNFFY"
     gene            4524..5690
                     /locus_tag="ACHDPO_002581"
     CDS             4524..5690
                     /locus_tag="ACHDPO_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFN3370149.1"
                     /translation="MKISVFGLGYVGLANSLLLAQKEQVKAYDIVEEKITMLQNGISP
                     IEDKEVHEFLKRDDLNVEFTSNFTDAVNFGDYLIIATPTDYDEKKNYFNTSTVEDVIE
                     KALAIRPDSTFIIKSTVPVGYANEIKAKFGTENIIFSPEFLREGKALYDNLYPSRIIV
                     GECSARGREIATMFQRNAFNKDASVLLTHSTEAEAIKLFSNTYLALRVAYFNELDTYA
                     EFRGLDSKQIIEGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLRANYEKVPSNIISAI
                     VDANTTRKDFIAGQILAKKPNVVGIYRLTMKAGSDNFRYSSIQGIMKRIKAKGIEVVV
                     YEPTLDEDEFYHSQVLKDINEFKNISDVIVSNRFEDILKDVEEKVYTRDIFGDN"
BASE COUNT         2388 a          900 c         1277 g         2340 t
ORIGIN      
        1 aaatcaaaaa aataattcta ttttaggcat gaaaatacga aataaaatta atcaacttaa
       61 ccaaatgaaa aaacgagata atctgttgcc agcaaaatat acccttaaat cgatgaccgg
      121 taaggggcct attaaagact attcaaacag agagaatcgc agtgatgaac taagaaaaaa
      181 agagttaact aatcaaggaa cacctaaaag gattgctgtg tatagttgta tcactggtaa
      241 ttatgattct attaaagaac cggatttttc tcatccattg gtagattact atttgtatac
      301 agataatgtg attacaagtg agcattggaa tattagagag atacctaaat atatatcgga
      361 attaaaaaat aatattttga tcaatagata tattaaattt catcctaatg agctatttac
      421 tgactacgat tttactttgt atgttgatgg taatgtaaca ataacttctg atattaccgg
      481 attactgaac agttcttcca aacttgggtt aagtatgcat aaacatagtg aaagaaaatc
      541 tttatattct gaggcagatg cattaattgc agttggcaaa ggtaataagg aaagtattat
      601 agagcaaatt agtaagtaca gagaagaagg atttcctgat aattttggat tggctgaagc
      661 cacggttatt ttagttgatt taaataattc aatcgctgag aatcttctag atttgtggtg
      721 gagagagtat ttgaactcag aaagtgggcg agatcagctc gcatttcctt acgtgttgtg
      781 gaagtccgga catgcaatga aggaagtgac taccttaggc aataatgtat ataaaagcgc
      841 taaattaaga atcataagtc attattagcc ctaaatgatt tctaaactat tctttcaaat
      901 cctagtaaat atttggagat agaagatttc ctttttaaag tcataaaaaa ttaagttata
      961 ttttttgagt gaatggagaa gacgcatagt atcataaact tcgttatatc ttaaattatg
     1021 gggtatgcct aaataataaa tgtaatacga gtataaagaa gaaagcaatt ttgggtttaa
     1081 ccctattggt tcctttcaga aaaaggtgga tgaataaaaa tgaaaatatt aataacaggt
     1141 ggagcaggat ttattggttt tcatttgtct agaaaattac tcaaggaaac tgaaaatcaa
     1201 attgtagcga ttgataatct caatgattat tatgatgtcc aattaaaaga agatcgatta
     1261 acgatactgt acgattataa taattttaaa tttatcagaa tggatctatt agagaaagaa
     1321 aaattagatt ctctatttga aagtgaaggt tttgacatag taattcattt agctgctcaa
     1381 gcaggtgtta gatattctat tgaaaaccct tatgcttata ttgattctaa tattatcggt
     1441 tttcttaata ttcttgaagc ctgccgaaac ttccctgtaa agcatctatt atatgcatca
     1501 tctagttcag tatatggtgg gaacacgaaa gtaccgtttt caacagaaga ttcggtggat
     1561 catccagtta gcctttatgc ggctaccaaa aaatcgaatg aattaatggc tcatacttat
     1621 agccaccttt ataaaatacc aacaactggg ctgagatttt tcactgtcta tggtccattt
     1681 gggcgaccag atatggccta tttctctttt accaagaata ttttatctgg aaaagaaatt
     1741 aagattttta accatggaaa gatggaaaga gatttcactt acatcgatga tatcgtagag
     1801 ggaatcacta gattaatcaa taaagtacct gaacccaact ccgactggac agacatcgat
     1861 gatttgagta gtgaaagttg ggcaccatat aagatataca atattggaaa taataagccg
     1921 gttgcattgt tggagtttgt tgaaacaatt gaaaagtatt taggtgttaa agcgaacaag
     1981 atttttttgg acatgcagcc gggtgatgtc gttagaactt atgccgatat tgaagattta
     2041 gaggaaaaaa tcaactttaa accgaatata accttggatg agggcattaa aaaattcgtt
     2101 gaatggtata cagtgtatta tttgagttaa ttttgaaagg aatattgaag atgggtaatt
     2161 catacgattt ttttagcttt gttaggtatt ttaggaaatt ctactttcaa acgtgacgaa
     2221 ctttctcgcc gaatagatat tttctataac taaaagaatt tctataaaac aaaattgtgt
     2281 atcaagatgt gtgaactgga ttctgactgc caatattgat tgatgagatt gaagaaatat
     2341 atagttgatc atggatatct ttatttgaaa agatcttagc tattcacata ttcaaaaaaa
     2401 tttttactac gaggactcac acgatacaga ggaatttagg tagttctaat taaaccagaa
     2461 agtcatctat agatgtgagt tgagggaggt catacggttg gatagtagca gtaataaatc
     2521 acattcaata gctaaaaaag cttttattta cgcaatagga acattatcat caaaaatgat
     2581 atctgtcatt ataatcccta tctatgcagt atatatttct gttgccgatt taggaagctt
     2641 tgattatcaa aatacaattg ctcaatttct ttctccagtt atttttggag caatatggga
     2701 agcaatttta cgcatgggat taggcaaaga aaaaaatatt cagaaaaaag tagtgacgaa
     2761 cagtatttgt tttgttatag caaatacagt gatattagcc atttttttac caataatata
     2821 tagaatgatt ttcccgaatt tagagtatta tcaattgttt gtttttcaat taattttcac
     2881 tcctatccta agtgtttttc aatatattgt aagagcacta ggtgaatcaa agatttttgt
     2941 gatgagtggt ataatcgctg cgggtatcaa cctgttactc cttactattt ttgttgttac
     3001 aatgggtatg gggatacttg gtctcttact ctctatcata atttctaatg ttataaattt
     3061 gatttttttg attttcaggg ggcagatctt tcaatatttc gcaacgagtt cttttgattt
     3121 tttattttta aagtccatgc tgaaatactc tatcccactc actttgaatc tcacttttgg
     3181 atggctaata gttggttttt caagatttta tattggaacg tacatcggag taacagaaaa
     3241 tggtattttt tcttttgcga tgaaattttc atctataatt ttaactctta caagtattgt
     3301 tagtatgtct atgatagagg atgcggttat cacgtctgag aatgatgatt tcatcgaaag
     3361 attcgttgag aaaaatacct atatttttaa aatgtacatt aggttagcga ctctttctat
     3421 tcctatcatt tgctgtgcat actcttttat aaccaaccct gattataaaa aatcattagt
     3481 tctagttcca atattagtta ttatggcatg tttcagtggg atgacaacaa atatcggaaa
     3541 tatatttgca gtatacaata aaacaaatca gttattaatg atttcagtag tgtcaggtct
     3601 attgagtgtt gttggcacct atttattagg ctattctttt ggagtaattg gtgtctcatt
     3661 tgctactttg ctcggtactt tagtattatt tggacttaga tattattttg gaaggaaaat
     3721 tgcttattat gcatttgatt ggaagcgaat atcgctactt ttagttctct attccgcaat
     3781 cgcttttgta tgcattcata gaggcttcta ttttaatctt ttcttaacga ttatttttag
     3841 tgctattttc gtttttacgt ataaacaatt aattataacg tatctaaaaa aatttttcag
     3901 aataaaaatg gctaaaaggt gagggtatac gaagtaagaa tagaatcttt cgaagaataa
     3961 agagaaaact atttggaaaa aatctgcgag aatgtattaa tgaaggtttg atattcggaa
     4021 aaaaacatag tttagtagag gttcctgaat ttgggagcga gccatattta attgaaatag
     4081 gggataattt cagatgttca tttggtgtta aatttataac acacgatggt ggagtctggg
     4141 tcttaaggaa gatgagttct gtgagcgagt caacttcaaa aataggtagg atcaaattgg
     4201 gaaataatat ttttattggt atttactcta ttgttttccc aggagtttca attggcgata
     4261 atgtaattat tagagcgaac actttagtaa ataaagatat cccaaataat agtgttgtag
     4321 cgggtagttc atgtaaagtg atttcaacta tagaggagca ttatgagaaa aataaaaatg
     4381 aatttattaa atatcgaacc tcgatgattt tgaagcaaaa aaattttttc tattaaataa
     4441 tattgattga ataaggaata tgttcaaaag gataacagct aaaatactat aaaatgaaat
     4501 ttgattggag cgtatggaag aatatgaaaa tttcagtttt cggattaggc tatgttggtc
     4561 tagcaaattc actattatta gcacaaaaag agcaggtcaa agcttatgat atcgtggaag
     4621 aaaaaatcac gatgttacaa aatggcatct caccaataga agataaagaa gttcatgaat
     4681 ttttaaaacg ggatgactta aatgtcgaat ttacgtcaaa ttttactgat gcagtaaact
     4741 tcggtgatta cttgattatt gcaactccaa cagattatga cgaaaagaaa aactatttta
     4801 atacatcaac agtagaagat gtaattgaga aggctttagc aattcgtcca gattcaacat
     4861 tcattattaa gtcgacagtt ccagttggct atgcaaatga aattaaagcg aaatttggta
     4921 cagaaaacat cattttttca cctgaatttt tgcgtgaagg aaaagctttg tacgacaact
     4981 tatatccatc aagaattata gttggagaat gttctgctcg tggtcgcgag attgcaacta
     5041 tgtttcaaag aaacgcattt aacaaagatg catcagttct tttgactcac tcaactgaag
     5101 cagaagctat taaattattc tcgaatacat atttggcatt gcgagtggcg tatttcaatg
     5161 aattagatac gtatgcagaa tttcgtgggc ttgatagtaa gcaaattatt gaaggtgtcg
     5221 gtttggatcc acggatcggt tcgcattata ataatccttc ttttggctat ggtggatact
     5281 gtttacccaa agacacaaaa caattaagag ccaactatga aaaagtacca agcaatatca
     5341 tcagtgcaat tgttgatgca aatacaacaa ggaaagattt tattgctgga cagattttgg
     5401 cgaaaaaacc aaatgttgtt ggaatctatc gtttaacgat gaaggccggt tcagataatt
     5461 ttcgatattc gtcgatccaa ggaattatga aacggattaa agccaaagga attgaagtgg
     5521 ttgtttacga gcctacattg gatgaagatg aattttatca ttcacaagta ttgaaagata
     5581 ttaatgaatt taaaaatatt tctgatgtga tcgtatctaa tcggtttgaa gatattttaa
     5641 aggatgttga agaaaaagtt tataccagag atatctttgg tgataactaa ataataatga
     5701 acgggtacat ggaggaaaat attttagatg gtgactcgaa ataaatgttt gttctcattg
     5761 catctgtatc tataccgata agtttaaaaa ttccgattag gaaaatgaag ttggctatcc
     5821 ttgcgaggaa tttattgctg gattatttta tgaactaaag caagacatca tcagaaaaaa
     5881 atccaaaatt tgacaatggg attgatcgtt taccagctgt aagcgaagta tctgacacga
     5941 aaatggaaaa tgcaattact gttattacca atagcttttt ttcatcgatc aagtatttga
     6001 aaacattatt tgtttgccaa gctgatcaat gttctttcag acttggaaga acattgatca
     6061 gctcacaagt aatgattgaa gtttaggtta tgggataaag gataagtgaa ataaaagtcg
     6121 tgtctgcatc tttgttagta ccagtaaatt tttctactac ggcgctagtc acgacagtcc
     6181 aggcatctga aattgaagat gcaaatagag tttctgctag tttaggtatt gatgttactg
     6241 tattagcatt aatcttagag ccagtagcat ccaataggtg tagctatagt tctaatagta
     6301 taaaacaatg cagaggatat gattgcttta tgtctcggtg tgtcaggtca aaatagagtt
     6361 ccatatgggg cgatttctca atgaataatc ttatagatat aatcttgttt gctatttcgt
     6421 tatcactttt acttttcttc gattatttca aaaataaaaa tccaaaatat tttaagttct
     6481 tactatttat cattactgta ctagctgttt tatcgatgac agattttatt taacttatct
     6541 caaaaagtag ggaaccatat catttttcag taacatgcgt attatttgta taaataatac
     6601 aaaatgaaaa attatgatta ttctattgtc tttttagaaa gcgttttctg tgagctttta
     6661 atctaaaagg agggatataa aataaagaaa acctatttta tgctattttt ttgttgtttc
     6721 tgtgtaggaa tcctgtggta tataggtggt aatgaaaaga agattcatgg agttgtgaca
     6781 aatatttctg cggatgagtt cgtatttgaa gatgaaaaac agaacgaata tagtattcaa
     6841 aaaagaagct ctttgtcaaa tgatgttggt aaagagaaat cttagaataa tttggacaga
     6901 agagg
//
LOCUS       DAZAOD010000119         6706 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000119 DAZAOD010000000
VERSION     DAZAOD010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.121"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(141..1052)
                     /locus_tag="ACHDPO_002582"
     CDS             complement(141..1052)
                     /locus_tag="ACHDPO_002582"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFN3370150.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(1509..1937)
                     /locus_tag="ACHDPO_002583"
     CDS             complement(1509..1937)
                     /locus_tag="ACHDPO_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370151.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(1965..2603)
                     /locus_tag="ACHDPO_002584"
     CDS             complement(1965..2603)
                     /locus_tag="ACHDPO_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3370152.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(2607..4643)
                     /locus_tag="ACHDPO_002585"
     CDS             complement(2607..4643)
                     /locus_tag="ACHDPO_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFN3370153.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4769..5434
                     /locus_tag="ACHDPO_002586"
     CDS             4769..5434
                     /locus_tag="ACHDPO_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370154.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT         2162 a         1226 c         1012 g         2306 t
ORIGIN      
        1 gattctaagt aaaaaaaatt tttaaaataa aaagaactaa atcaagtagt aattaaacta
       61 ctgttgattt agttctaata aaaagattta gatgaacagt tttattgatt taaatagttc
      121 atatttttta tttataccgc ttatttacta cttgctgtac tagaatctga agtgaatgta
      181 ctcaaaacat tttcaaagtc tttgtctttg atttttacat tagcgtcttt caatacttcg
      241 ccaattactt tattctggaa ggtactgtca cttaattttg tgtctgttgc aatttctttc
      301 aattcttttt tgtatttatc catgtcgttg cctttgtttt ggtttttcac cattttaacc
      361 acataatatt ccgtagtata agttgaagca ttggtagaag tgatcacatc agaaacttga
      421 ccatctttca acttaaaggc tgcttctttg acttctgccg gaaccgttgt agtagtggaa
      481 tcaaatttca cttttccgcc atcttctttt gtcgtagtat cagttgactt gtctttggct
      541 aatttagaga aatcgtctcc cttatcagca gctttcttca catcttttgc atcatcttca
      601 cttgctactt ggataatttg agcttccact tctggatgga aagattccca agccgttttt
      661 aaatcttcat cggtcaattt gatatgtttc tttagacctt cttgaaaggc tagactttgt
      721 ttgatactgt ctttgaatgt ttgttctgtg taacctgcag atttcaattg tgaatcaaat
      781 gaatcaccca attgtttctt tgtttgatca tattgagaat cgatttcttt ggttgatacg
      841 tcatctccat atttatcttc aaatacttga taaacgatca actgttgcac agcggaatct
      901 gctccttgca tttttttcaa gctatccatt acttcttgtt cgctgattgt accgccttta
      961 taactaacgg ctgttttttc accggcattc gtacagcctg acaataagcc agtgcctagt
     1021 acgatggcaa gtgctaaaaa tctttttttc atttatcaat tctcctactt ttcgtttttt
     1081 gcgaattgct aaaaacaaag gtgttcaaga tgaaaatcat caagaacacc tttactaatc
     1141 tgctcgatac gtcctgaata gatataaggc tacacaatcc agaaagttcg ctcagcagaa
     1201 taaatgtcaa gtagcacatc acaccttaat atactacttc ttttgttacc gtttttcaag
     1261 tctatcttgc gttccgtatt taacgtaact aattcttaga acaaatgtta tcgattttgt
     1321 ttttcttctt ccgctgctgg gatattcaaa tcagacactt ttatgttcga ttttccagac
     1381 atttttttgt tgtttttatt atgatatatt tttatacaac taaaaatgaa tatattaaaa
     1441 ctaccaaaaa taacttttaa cgctgtttca ttatatgttt tttctatttt atataaactt
     1501 ttggatactt aataccaacc ggttggattg taccaacatg agaatgtgtc agttctattt
     1561 cctgtcgcac ttgcataggc ccatactcct tttgttgcat ttgctgatcg aatagagttt
     1621 ccaactttcg cttttgcacc gtgacgatta tagacacgac tatagtggtt agaatgacct
     1681 gtttttctcg tacaagttgt atcactataa taaacccatc ttccagagct atgattaatt
     1741 gctgttctag aaatttcccg gtctactggt aaatttgact taataatatt acctttagca
     1801 tcaaaatgaa tctctcctgg ctttaaagat ttgtaataga tttcaccgtg aactgaattt
     1861 gcttccactt cagatgacat agcgtttcct ccaacaaaac ctatccctag tgcacaaata
     1921 ataactgctt ttttcataaa acgacatcct ttcctttttg atttttaaag catgatcttc
     1981 ttgtttccta ttttggtcag atatggatca tgcgtgacta cgataactaa cgtaccttgg
     2041 gaagcttgtt gcgataagat ttcaactact ttatccttat ttcttttatc caatgaccca
     2101 gtcggttcat cggctaaaat gattttgcta ttcttcaata agactctcgc acaggcgatt
     2161 ctttgcttct caccaccaga taatgtgtag ataggcgtac ttagcttctt gtttatattt
     2221 acttttttca atgcctcata ctttgctgtt cgcttatctg aaacatttaa attcgaaaac
     2281 ttcaatccaa tatctaaatt aaaatcgatt gtttcatatt caatcaaccc aaaatcttga
     2341 aaaagaaaag atatggtatt tctttttatc aagcgcttct ctctcccagt taattgtttc
     2401 gtctcttgat cgaacaaata gaattgtcct gaactgaact gatcattcaa tcctaatata
     2461 ttcaataacg tacttttacc tgctccactt tctccaacaa cagtcacaag atccccagca
     2521 tccgcagtga aacgatccaa atgaagaatc gttttgtttc gaatgatttt tttcgcacct
     2581 tttatcacta tcaacggctc caattgttaa cctccattca tcagcaataa ctgacttttc
     2641 ttttctgtag acaaaataaa aacaactgaa agaataaaat caatgaagct aaagaaaaaa
     2701 atattaaaaa gatatttagg ctctctttct ataagaaaaa ggaagattac acttgtcgtt
     2761 ccccatttga tgaggttcat catgaagaaa tctttatacg tttcaaagag cgaataacca
     2821 cttgaacgaa agatagcgat tttccgacaa ttgtagacaa aatatatgca taacatgaca
     2881 tagctcaaca agaagaaaga aaagaaagtg agtaaaaata tctgtatcaa gtaatgaaat
     2941 gatctgctta acactttgac agctatctct tcagtctgag tatacggaaa tgataactgc
     3001 aagttatcac gtaactgact ttcttcaatc agctcaaata acctttcttt cgacaaagag
     3061 cctatcttga tctttaacgg tggatagatt tctccgctga gaatatttct ttccaaatac
     3121 atactgtttt tcaatgtcag tatttcaaca accggataat gttcgatcca ggggatagaa
     3181 ggaataaatg tataaatggg ttgattgttt tttataaata gaaatttcgg ttctttttca
     3241 ctgatttctt gataatattc tgttatttgc gccaggtcat tttttaaatc tgtatgtcta
     3301 tatcgttcag ggatcaatat aacagggtgc gtttcttttt cggttatttg gatcaacctt
     3361 ccagagacat caatcaaagg aaatttctta agataattca gatttatttt tatccctctg
     3421 ccaaactgtt cattttcttc attcaagtaa tctgatacat tgactaatat acttccgttt
     3481 ttattcaaag tttcatataa ttcctgatct gctgctgatg caaaacgatt ggaataaata
     3541 aaatccacgt ggtttttccc gatggttact ggataaaata catgatagtc ctcaccagcg
     3601 atttcttttg gtggttcatg ggaaacagct aactgtgaag aagaaaaaac gatagttgct
     3661 aattcgacat tggcaacggt caaaagaaga gaaaacaaca atccaaatgt aaaaagaatg
     3721 tattggatat agttgaacgc ttctcttaac gaagcgattt tttcaactaa taaaagagaa
     3781 atcaaagaga taccatatat tccgctgaac aagaaaacgt acatctggaa caaataaaga
     3841 aattgctcct tataatacat aaaaataaaa ccaccaatga ttcctgcaat tatgaatgta
     3901 ataatgattt tctttttccc caataaacac cacaatactt gatgtaatga aaagtcatta
     3961 ttcaacaata aactgatttc tttattcatc aataagaaaa aggatgataa caaaaggaat
     4021 aaaagaatca atccaatagt taaatacact cgataattat atacgtctgt atttgaaata
     4081 accgaatacg aatagctatt ttcaaagtct tcaaaaatat tagtggcata atcagtgtga
     4141 aatgcttgat tgaatcgatc agtgaatagt gaaatgaacc gttcataggc ttctttttct
     4201 ctcgtcatca agaaaaattc accttcaaaa tcttttattt tgatcgattc ttcaatggac
     4261 gttacgcgaa aggaggtatt agaatagggt accttctcgt gagaagattt gacatcccct
     4321 tgataataca atgtcatttc aagctttggc tgtatcttga agttccaaga tgtatctact
     4381 tcattggatt catttactgt ttttttcata taagaaagct cagtttctga tgagacattt
     4441 tcaaatacca tgattagctg ctcatattct tcttgcccaa taaaatgttg tggcaatcga
     4501 atcggagtat aagtatctgt ttgatggaaa aattcatttg tccgatagag tacctgttta
     4561 tttatactaa ccaaggcaaa accactcatg ataccggtca ctatgattgt gagtaaaact
     4621 gtgaactttt ttttgattat caccactctc ccttacttaa atgattcttt gataaaatca
     4681 taccgttttt catcaaaaaa acgtatctat caagtgtata ggtcatgtag aataaatcta
     4741 tatactgtag aatcgaaagg agaagaagat gaacaccgga gaaaaaatac gaacttaccg
     4801 cagaaattgt aagcttacgc aaaaagaatt aggcgaaaaa attggtgttt ccgataaaac
     4861 gatttctagt tgggaaaatt ctcgtacaat gccagacctt gaaatgctgt cacttttaca
     4921 tcatacttta ggtctgccga ttgattttcc ttctattgaa tcagctaccg aatcaataga
     4981 accaacattg ccagatgaac ctcttgttaa caagaaatct tattcatcaa aacaaccctt
     5041 ctcactcaaa aagacactat ctttctttct gctcgtcttt tgtttggtct atctttttct
     5101 tatcaattat caatacaaaa atgaaacgat cgatcgattc aatccttttt tgaaaccaca
     5161 aatcggctat accacactcc ctgtaggata cgtggacaat tccatcgaac gttgggtatg
     5221 taatgatatc tttggccatg gtacatggct gtcttttcac gctggagagg tagaaaaaga
     5281 gaaaaaccat gctgtaatca aacacaaagg aaaacacgtc atgaacgttc gcctgctcac
     5341 ttgggaagcc attccctcag attaccaaga aatcctcagc caagactatg acgacgcctt
     5401 aaaaagaagc cctcaggagc cagataggca ttaagtagga gatgaacgta gagatagaaa
     5461 aaatcaatgc acatgatctt atccaaaaaa caggggtaca aattaattga aaaagccttg
     5521 agatgaaagt tcctaaataa aaaagttcag aatgataggt atttctggct tatagtataa
     5581 tatttacgcc acagcctccc aatgattctt tttggaatca taatcaagga tggacattca
     5641 caaaaatatt ttgctcattc gatccgaata gattaacgac caatctagta agtaatatag
     5701 attggtacgt agtcaagctg cacataattt agatcaattt tagttctttt ttatatttct
     5761 atgatctgct catttacttt tatatgatgg cttacagtaa cataaataaa tatgataatc
     5821 gctggtagtt tatccaagag tactcaataa aatacaaaat ggattgttca agcgcctatc
     5881 ataatgataa aatgaaacaa ataaacgata caaggaggaa gagactttga gtaatggcag
     5941 aacaattttt tcattgtaaa aattgttcag ttgttaatct atgggatttc ggtagcatgg
     6001 gcattttttt atagaggaat cacaccaacc tggccgtttt atctcttgtt agtgggaata
     6061 ttagtaggaa attttgcccc tcttcactat cgtacgaact tttttccaac tgattctggc
     6121 ctttttctta aaacaaagac gcgaaaatta gaaaacatta ttgaaatgac aattacctgt
     6181 ataatcattt tcttagttat attcctaaac gtcttctaat aagaatctct taaaattagc
     6241 ttgttacagt tagttaccta gtttatataa cacagttatc ttatcttcct tatcaacatc
     6301 ttttgccaac tctttgtctt aaattcgaaa catataagca gagctacgaa caccaagact
     6361 gtttcggctc tgttttttgc atcaaattca ctcttatata gctgataatc tcggctcttt
     6421 aaaagaaatt attttcgctt cattttatta taaaaaggct aggaaccttg atgttatcag
     6481 gttcctagcc tttatttaag tattacccca cagacccttc catatagatt tttaaattac
     6541 acactagttt aaactaaaac aaacaaggaa acacttacca tttaatcata aaattagctc
     6601 atatgaatat attagaatgt aaaatagact ggtcaaaatc tggtcaaaaa agaggactaa
     6661 tacaggtagt cctcagactg tagacaaagt ccattttatg gatgat
//
LOCUS       DAZAOD010000120         6552 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000120 DAZAOD010000000
VERSION     DAZAOD010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.122"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            68..2743
                     /locus_tag="ACHDPO_002587"
     CDS             68..2743
                     /locus_tag="ACHDPO_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HFN3370155.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            2925..3164
                     /locus_tag="ACHDPO_002588"
     CDS             2925..3164
                     /locus_tag="ACHDPO_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370156.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3180..4553
                     /locus_tag="ACHDPO_002589"
     CDS             3180..4553
                     /locus_tag="ACHDPO_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3370157.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4557..6191
                     /locus_tag="ACHDPO_002590"
     CDS             4557..6191
                     /locus_tag="ACHDPO_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3370158.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6354..>6552
                     /locus_tag="ACHDPO_002591"
     CDS             6354..>6552
                     /locus_tag="ACHDPO_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370159.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2299 a         1062 c         1318 g         1873 t
ORIGIN      
        1 aattatgaga ggttggaggt aatgtagtca tacaaataaa aattttttag aaagtgagtg
       61 gtaattaatg aaaatgaatc acacttcaat tcagaagcat ttacaactgt taaatacact
      121 ggggatttct tatgttaatt tgagaacttt ttctacatta aacaagaaaa ccgtttctca
      181 tattttttct actgcagatt ctcaagcaat tattaactat ttagaaaaac agaaattgtc
      241 tgaaggtaca gtaaacataa cttataatcc tattaaacaa gaggtgatta cacaaaaaaa
      301 gcattctgtg agagacaatg atattgaaaa aattcggttt gtatttattg atattgaccc
      361 taaaaggaaa gagggaagtg caacagatag cgaaaagaaa aaggcagaaa atgttatgga
      421 acaagtagaa cgttatttga aagaaaagag aatagaatca tttgtaaaag ttgatagtgg
      481 gaatggctac catatttttc ttcccataaa tgaacaacca aataatcacg agacgattct
      541 tactattcag aattttcttc aattacttca ccgaagattt ggagtagaag atgaagttga
      601 tattgatact tctgtttata atccttcaag attatgcaaa ttagttggta caccagcggt
      661 caaaggaaag tccacaaaag agcgtccgca tcgtttatct agtttccttt ctattcccga
      721 taacatagat agaagtaatt gttttaaaat tcttgaacag atagttgaag aaaattccat
      781 gatgtcaacc tctagagtaa aaagccatcc atcttttaga gaagtgttac cttttattca
      841 agcagactat aaacaatggt tagctcacta tcctgaatta acttatacca taaaagaggg
      901 cgatcataaa ggagttacct tacttatatt tgacgaatgt ccattaagaa aacacacgaa
      961 taattctaat ggttcttgtt tgtctgttac ggctgataat aagattcgat ttcattgtct
     1021 gcatgcttcg gataaaaata aagatattca agactttgta aaaaaatatc cgttgccaaa
     1081 acctgtaaat ccttctgtag aatcattaga atccaatcaa gaatattatt ttgaccagtt
     1141 taaactgaat caagaaggag tatttttggt gaaagaaggt caagaagaaa aagttgcttg
     1201 tccgatgttt attaagcaaa tacgcaaaaa tatcgaacaa aaagtcatta cacttgttct
     1261 tgcctattat gtcgatcatt gttgggatga aatagaaata gaaggtggat gtttacaaac
     1321 taataatttt aaacaattag caaaacatgg cttaatcatt aaagctagaa gagaagctga
     1381 agtcgttgac tttttacaga ttcaacggga gaatgctcca atcttttttg aacatgaatc
     1441 tcttggctgg aaaaaagaaa atgaagcaat gatttttcag ttacaagatt cttttggacg
     1501 tgaaattcct tctgtattaa ctaaaaactc atgctaccaa ttaacaacta atggtacaga
     1561 agcggaattt gacgcattgg ttcataagta tgttttagga acgaacttag aacttgcttg
     1621 gtcgattggt attgcttcta ttgtgttagg ctatttaaac gttacgaagg ctaatacttt
     1681 tttgagttta ctaattaacc tacagggcaa gagcacaacg ggtaaaacca ctacgttaca
     1741 ctttattgcc tctttatttg gaaatccaac tacggttctt agaaatatga atgctaccaa
     1801 taaagccatt ataaagctag catcaaacaa tcagggaggt gttccactaa tactagatga
     1861 gttaggagca gcaactcaaa ataactttag ctcgttgatc tatcaattag cttcaggaga
     1921 agaaaggcta agattagatt ctaattgtca gcttatgcca caagagactt tttctgtttt
     1981 gacccttacc tcttctgaag agcgtttgga aaattatttc aatgagaaat taactggttt
     2041 gaaagttcga tatatcgaat tttctgatat caagtttaca aaggatgcga atcacgcaga
     2101 gaaagttaaa agtctttctt ctaatacttt tggttggggt ataaagttat ttcttttgaa
     2161 actctttgaa caagggatta caaaaattga agcaactttt gtcgaagctc aaaaaaaact
     2221 atgggctgtt ttacctgaac attctttgaa gcaacgcatt ggtaataatc tagctttgat
     2281 ttatagtgga gccctcctaa ttcaagatat actgggctat cctttacgat tagagcatat
     2341 acagacggtg cttattaatt cgtacgaaca gttaattgta gatactagtt taggaagtga
     2401 gcaaacggta tttgaccgag tgaaaacatt gttggtgatg aatagccata aatttttaac
     2461 aaacagtgac aacaaacata cgcccagtac gatttgggga aaagtatcaa ttcaaaaaaa
     2521 tggggatatt aaggtaaata tttttcctat cccgtttgag gacttgttaa ggcgagaatt
     2581 tcaagtaaag gatctaacct atctttttag gcaattgctt gattcgggta atatgtgtgc
     2641 agaaaaaggg agaagaacga aacgtattca catgaatcgt caagttcttc caacatacga
     2701 gattctatta ccttcttcac tcaaatcgta ttttcgattg taatttagaa taaaccaaag
     2761 tatgaaagtg aggcaccatg ttatggaaat atttcttatt gatttagcaa aacaactgat
     2821 tacttatctg tatgatagcg agcaaaccca aacggaagta aatgaagctt gatctatgct
     2881 tcatttactt cattcaatca aacatgaaag aaaggaaaat tctaatgact aaaaataaaa
     2941 tgacactaaa agcagaggtt cttctgtata ttcaagaaca tttttcaaat caagcctttt
     3001 ttacaaaacc aatttacttg gatttcgaaa taagaggggt atctgctgga tctatcgggg
     3061 gtactcttca agcgttgaag aacgaaggat atttagaaaa tcactttgtg caacgttcgt
     3121 tcaatagaag agtcgtgaaa aaatggtatt tagttcattc atagagaggg gaatcaagca
     3181 tgcgtgtggc ttgttatgat cgaacgtctg tttatgaaga agcgaaaatt agtaatgacg
     3241 ctcaatatga tgcagtgaaa gagtatgttt tagagaaata tgaacaaatt ccccaacgat
     3301 tttcagacaa aggagaatca ggggaaaaag cggagcgtcc agcttttcga cagcttagag
     3361 cttgggtttg tgcgtcagaa gaagaggggg tgatctatgt ttggcgttat gatcgattgg
     3421 cacgtcaagc caaaatagcc ttagaattta ttgagttgtg ccaacaacat caggttcaag
     3481 tgtattcgat ttctgaacct cttcctgctt ctttctcaca cgcgtcaacg aataaactat
     3541 ttgtgcaatt attgttcact tttgcagaac aacaacgaaa cgtcattatt gagaatgttc
     3601 gtgccggact ttcctataaa aagcaacaac ggcaatattt gtcttctgcg gtaccatatg
     3661 ggtatcgttt agtgaatggg aaaatccaac aagaagtaca cgaagcaagg attgttcgct
     3721 atatttttca actttatttg accaaaaaat atggctacaa aaagctttgt caacgattga
     3781 cgcaacaaaa gcttttcttc cgcgaacgtc cttttcagcc ctatcatatt tatagtatcc
     3841 taaaaaatcc attgtactat ggcgaaatca aaggaggatc tttggggaag tatctaggaa
     3901 cctttgaacc gattctctcg aaagcaacct ttttacaagc ccaagagatt cgccaatcaa
     3961 ggtgtacagc taaaaaagat acgtatctgt acttattacg tcaaaaaatt cggtgtccct
     4021 tctgtggtcg tcatctgagt tcgaagtatc aatggaatac aaagaagacg aagacgcttc
     4081 attattatca ttgtaccgac cgaagctgcc aaggaatttt tcttcgggca gaaagggttg
     4141 agtcagaagt attggaaaag atacaggctt tttttcaata cgaaggcgtc tatcaagcct
     4201 tgattgccca attaacgcaa caattagccg aaaagcgaaa agatgaaaaa cgcaaagtaa
     4261 tccaacaaaa gaaacaagaa gcacaatgga ttaaggcatt tgaagagggc aattgttcac
     4321 tggaagaact caagcaacaa ctgcaagctc ttcaaaagcc gatgtctact tcttcgtttc
     4381 tttcactcca acagtgtgaa gcaaaagtga aagaatggct tcaactaaaa gacctctcta
     4441 gtcgacaatt attatgtgac tatgtttgtc ggattgaggt aacaaaggat aaaacagttt
     4501 gtgggattta cttccgacaa ctgacacaaa atattttaga aaggaacgaa tgatctatgg
     4561 aaatgataca aaccaaacga gtcgcattgt atattcgcgt gagtacacaa gaacaagctt
     4621 tagaaggaca tagtattcaa gcacaagaac aaaatggacg acagtttgcc gaacggatgg
     4681 gctatgaagt ggtagaagtt tatgccgatg aaggaatcag tgggaaatcc acaaaaaatc
     4741 ggttcgccta tcaacgaatg atgaacgatg ctcggaacca tcgttttgat ctactagtga
     4801 tttggaaatt gacccgtctc ggacgcaata tgttagatgt cttacaaaca gtcgaggaat
     4861 tattgcgata tgacgtagga ttacattcga tctcggaaca atttgacgtg accacttcga
     4921 caggtaaatt gatgttacaa ctccttggga gtttcggtga atttgaacgc aaccaaattg
     4981 cggagaatgt tcaaatgtca atgcaaagct tagtgaaaga taaaaagcgt tatgcaggag
     5041 gccgacgttt aggctatgtc agtggtattg acacgaatgg tcaaaaacaa ttggtcattg
     5101 aaccagaaga ggcgaaaatt gttcgtctga tctatgcaaa atatttaggc ggagcagggt
     5161 atcgagcgat tgccaatttt ttgaatcgtc aaggatatca aacagtcaaa aagaatgctt
     5221 tttctaccac ggcagtcaaa gatatcttac gcaataaaat ttatgcaggg tatttagaat
     5281 atgcgcgcta catcaattgg gaaaccaaac gacggaaggg gaagaatccg agaccgattt
     5341 tagtgaaagg aacccatgaa ccgattattt cggaagaaga ttatcaaaaa gtacaagaac
     5401 gccttgcttt agaaggaaaa caacccaaat ggaaccatac aggtgaaaat gtattgacag
     5461 gcttgttacg ttgtccagaa tgtggcgcac cgatggcagc gagtaatgtc acaaataccc
     5521 taaaggatgg cacaaagaaa cggattcgat attattcttg ttcagtcttt cggaataaag
     5581 gagcaagtgt gtgtcatgcc aattcgattc gtgccgaaca agcggaaaca tttgtcgccg
     5641 accgattaaa ggagatcgtt cagctaccag aagttcttcc ccgattggtg gcagcgttaa
     5701 atgaagaaat agtgcgacaa agccaaccat tggaacaaga actcgtggtg ttactggaac
     5761 gaaaggaaga attgaagact aaaattgaaa aatgggaagc tgctttggaa gatagtcctg
     5821 aattgtttcc gatgttaaaa gaccgcttag acgaattgac tgaaaaacga cgacagttgc
     5881 acattcgaga aaatgaaatc ttagggatct ttcaacaagg agagccgatt caagtcaaag
     5941 atgtccaacg gatattgact agtttggatc gttttcttgc ccagagtgag aagaagcaaa
     6001 tcaaagcctt gtatcgtacc tttatagaga aaataacctt tgatcctaac cataaggaga
     6061 tgttggaaat tacgatgaaa ttcacgcatg ccgtggtaca acaattgaat gagcaatatc
     6121 aaatagccgt atccaaaaca aaggatacgg ctatttttgt gttaaaaaca ccctttacgt
     6181 taacgatcta gtctaggtta tatcaaacaa cgttagaggg gcgctaacgc ttctctagcg
     6241 atttgaaatc gttagagaag tagttaggga ggtccttatc ataaataggg atatttatta
     6301 atgaatattt gaaatataat tgtatataag aattaaaaag agtggggata gatatgaaaa
     6361 agatgggtaa gtgtatttta tgtgaaaaat acactgaact tactaaagaa catgtaccac
     6421 ctaaaaaatc agggaatact ggaggtaaaa agaccagaac tggtaattta gatgatttcc
     6481 ttaagagcga ttttacaaaa ggtgattttc cgaaggggat taaaaggaaa cctcaaggaa
     6541 atgtttatta ta
//
LOCUS       DAZAOD010000121         6352 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000121 DAZAOD010000000
VERSION     DAZAOD010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.123"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(99..1229)
                     /locus_tag="ACHDPO_002592"
                     /pseudo
     CDS             complement(99..1229)
                     /locus_tag="ACHDPO_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACHDPO_002593"
     CDS             complement(1878..3080)
                     /locus_tag="ACHDPO_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3370160.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACHDPO_002594"
     CDS             complement(3140..3343)
                     /locus_tag="ACHDPO_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFN3370161.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACHDPO_002595"
     CDS             complement(3485..4552)
                     /locus_tag="ACHDPO_002595"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFN3370162.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACHDPO_002596"
     CDS             complement(4610..4717)
                     /locus_tag="ACHDPO_002596"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370163.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACHDPO_002597"
     CDS             4880..5692
                     /locus_tag="ACHDPO_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370164.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACHDPO_002598"
     CDS             complement(6066..6257)
                     /locus_tag="ACHDPO_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370165.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT         1898 a         1301 c         1002 g         2151 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagctaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac ag
//
LOCUS       DAZAOD010000122         6343 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000122 DAZAOD010000000
VERSION     DAZAOD010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.124"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..572)
                     /locus_tag="ACHDPO_002599"
     CDS             complement(<1..572)
                     /locus_tag="ACHDPO_002599"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFN3370166.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNE"
     gene            complement(727..1253)
                     /locus_tag="ACHDPO_002600"
                     /pseudo
     CDS             complement(727..1253)
                     /locus_tag="ACHDPO_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1710..3221
                     /gene="gadC"
                     /locus_tag="ACHDPO_002601"
     CDS             1710..3221
                     /gene="gadC"
                     /locus_tag="ACHDPO_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HFN3370167.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            3234..4634
                     /locus_tag="ACHDPO_002602"
     CDS             3234..4634
                     /locus_tag="ACHDPO_002602"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004351 - glutamate decarboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006540 - glutamate decarboxylation to
                     succinate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HFN3370168.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(4799..6234)
                     /locus_tag="ACHDPO_002603"
                     /pseudo
     CDS             complement(4799..6234)
                     /locus_tag="ACHDPO_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
BASE COUNT         1962 a         1098 c         1153 g         2130 t
ORIGIN      
        1 tcttcgttgt agtagtggtt gcgacatacc gaaaggtaat cttcattacc tcctactaca
       61 atctgttcac ctgaataaac tggaatacca tcaacaatac gagcattcat tacagccttt
      121 ttattgcaaa aatggcaaat agttttaatt tcctcaattt tatcagcaaa tgtcaataat
      181 gcttcggatc ccttgaagag attattttga aaatcattct tcaatccata gcaaattact
      241 ggtacttcct cattcattac gataagtgat agatcaataa tattctctct acttaaaaat
      301 tgagactcat cgaccaaaat acaatcaact tttccgtact gatcaataat ctccactaat
      361 tctccgtaca catccatttc agaagtaatt gcaatagctg gtttcgaaac acctatacga
      421 ctctcaactt ttccaaatcc tgatcgagta tctattgcgc ttgtcattat gataactctc
      481 ttcccttgtt cttcataatt atgagccact ttcagtagct caatactctt tccactattc
      541 attgttccat atctgtaaaa taattgtgcc attaaattta ttcccttctt ttacaattca
      601 attattcctt aattccatct gcttttatgc agctgctcgt ttattccttg atatgtctat
      661 aacatctact atccctaaaa ccaatttata agccattaga gatggtattc ctgaacatct
      721 ctcatattgt tttttgagtg gtatatcatc tgaaaaactg aaggaatcat gaaaatagcg
      781 acatacttat catttagagt tctaacttta aatgcattta cttcttcagt cagcacttta
      841 gtcatgttgg acatggtttg gggcgtgtag tgatgcccat acattttctc aatcaagtct
      901 gcgatttccg acatggtaat accttttcgg aagaggtgaa tgacggtctc ctctaatgtg
      961 tcattcgtcc gtctataagc aggaacagtc tgttgcttga actcgccatt gcggtcgcgc
     1021 ggaatctgga gatgaagttc cccatactcg gtcttgaccg tacggtcata ggagccgtta
     1081 cgagaattac ccgtgttaaa accaatgcga tcgtactttt cgtaatcgag gaaagccgtt
     1141 aactccgttt tgagaagcgt attgacagct ttttccaaat ggacacggaa taatccattc
     1201 aaatcgcctt tgttcgctag agtctttagg atttctgtag taaaatcgtt catatggaag
     1261 tcctcttttc tgtgaatgtg ttgtggtaac tctattctac agaagggact tccttttttc
     1321 tatttacaca aaatatttta cactctcaac aaaagtatct tcgattaata cttgctcaag
     1381 ttatgtgcag ctacgaaaaa gtaggtaccg aggtactttc tttttcgcag ctttttttgg
     1441 acttatgaga agtacattcg ctggaagaat acgatataaa acgagctttt tcactaaaga
     1501 tattaataga gtgaaagaaa caagcttttg ttgtcagttt tttcactttt ctaaaaatga
     1561 aaataaaaaa ttctggaagt ggagaagaat tttgcttgct atactttgtc ttgtagaaaa
     1621 gaggtagaca aaataatgca agctcaaata agcgattttc cataaccttg gtaggaatga
     1681 caaattaaat aggaaaggga agtaataata tgaataaaaa aaagttatct ctattcggtt
     1741 tttttgccct gacagcttcc atggttttga ctgtttatga gtatccgacc tttgcaacat
     1801 cacaattaca tttggttttc tttcttcttt tgggaggtat tttatggttt ctaccagttg
     1861 ctttatgtgc tgcagaaatg gcaacagttg aaggatggaa agatggtggg attttcagtt
     1921 gggttagtca aactttagga gaacgttttg gttttgcagc tatttttttc caatggtttc
     1981 aaattacagt aggttttatt acaatgatct acttcatact aggagcgctg tcgtatgtaa
     2041 ttaattttcc agagcttaat acagatccat ttatcaagtt tattggtgta ttagtcattt
     2101 tctgggtact gactttttca cagttgggcg ggaccaatcg taccgctaaa attgctaaag
     2161 caggatttgt cattggaatt gttattcctt cgatcattct ctttggttta gcagcagcct
     2221 actttatcgg cggtaatccg attcaaatgg ctattaatgc gaaagctttt attcctgact
     2281 tttctcagct ttcaacttta gtagtatttg tatcttttat attggcttat atgggcgtag
     2341 aagcttcagc atcacatatt aatgagctgg aaaatcccca aagaaactac ccattggcaa
     2401 tgtttttact agtgattttg gccatcgcct tagatgcaat cggcggtttc tcagtagcag
     2461 cggttattcc acaacatgac ttgtctctca gtgctggtgt aatccaaaca tttgaaacgc
     2521 ttattttaca ttttaacagt catttacatt ggttggtaaa agtgattgct ctcatgattg
     2581 cctgtggcgt tatgggtgaa gttagttctt gggtagttgg tccatcacga gggatgtttg
     2641 cagctgctca gcgaggtctg ttaccagttt tcttccggaa aactaataaa caagacgttc
     2701 cagttccgtt gattatgata caaggaatta tcgttactat ttgggcagca gtcttaactt
     2761 ttggtggagg aggcaacaat ttatcattct tagtagcaat ctccttaact gttgtcattt
     2821 atctcgtagg atatttacta tttttcctag gttactttgt attagttttt aagaaaaaag
     2881 acttaaaacg aacttacaat gtaccaggaa aaactgttgg caaaacgatt atcggtggaa
     2941 ttggttttat tttatcagtg ttcgcattgc ttatctcttt tgtaccacca gcttcaattg
     3001 cagctagtga gcaccgaaca taccaaatca tactacttat tagctttgta gtgactgttc
     3061 ttttaccttt tatcatttat gaagtacatg ataaaagtgc tcacacaact attgaggaac
     3121 ctactcacgt gaaagctgaa gacgttaatc ccgctgttta tccagctgct agaggagagc
     3181 accacgttac aaaaaatgat gaacatattt taaaacatta ggaggaattc attatgttat
     3241 acggaaaaga taatcaagaa gaaaaaaact atttggaacc aatttttggc tctgcaagtg
     3301 aggatgttga cttgcctaaa tataagttaa acaaagaatc cattgaacca cgaattgctt
     3361 atcaattagt acaagacgag atgttggatg aaggaaatgc gcgattaaac ttagctactt
     3421 tttgtcaaac gtatatggaa cctgaagcag tgaaattgat gacccaaacg ttagaaaaaa
     3481 atgcaattga taaatcagaa tacccacgaa caacggaaat tgaaaaccgc tgtgtaaata
     3541 tgattgctga tttatggcat gctccaaata atgaaaaatt catgggaact tcaacgatcg
     3601 gctcttcaga agcctgcatg ctgggtggta tggccatgaa atttgcttgg cgtaaacgtg
     3661 ctgaaaaatt aggtcttgat attcaagcaa aaaaacctaa cctggtgatc tcttctggtt
     3721 accaagtttg ttgggaaaaa ttctgtgtat attgggatgt ggaactgaga gaagtcccaa
     3781 tggatgaaaa acatatgtca attaatctag atactgtcat ggattatgtg gatgagtaca
     3841 caattggtat tgtaggtatt atgggtatta cttacactgg tcgttatgat gatatcaagg
     3901 gtctgaatga tttagttgaa gctcacaata aacaaactga ctataaagta tacattcatg
     3961 ttgacgctgc atcgggtggc ttttatgcac catttactga acctgatcta gtttgggatt
     4021 ttcaattgaa aaatgttatc tcaattaatt cttcaggtca caaatatggt ttggtatatc
     4081 caggtgtggg ttgggtctta tggcgtgacc aacaatactt accagaagaa ttagtattta
     4141 aagttagtta cttaggtgga gaaatgccaa ctatggctat caacttctct catagtgcag
     4201 cacaactaat tgggcaatac tacaactttg tacgctatgg ctttgatggt tatcgtgata
     4261 ttcaccaaag aactcatgat gttgctgttt atttagccaa agagatcgaa aaaactggta
     4321 tttttgaaat cattaatgat ggatcagaat tgccagttgt gtgctataag ctgaaagaag
     4381 atcccaatcg cgaatggaca ctatatgatt tatctgatcg tctgttaatg aagggatggc
     4441 aagtcccagc ctacccatta cctaaagact tggatcaatt aattattcaa cgcttagttg
     4501 ttcgagcaga ctttggaatg aacatggctg gtgattatgt acaagatatg aaccaagcaa
     4561 ttgaagagtt gaataaagct catattgttt atcataaaaa acaggatgtg aaaacgtacg
     4621 gctttactca ctaaaattct tcagagaaat ataaaagaag ttaattaact aataaaagga
     4681 gttgtgatta ccacacagct ccttaaatct atttgaataa atatatgata ttcatttgtt
     4741 acactctcaa tcttagctgt tgttctattc atcattactc ttattgtaag tagttcagtc
     4801 aaatttgctt gttcaattga tcgataacag tatgaattgt ttgaaaagta atcggatata
     4861 taattgtttt ctcactacct aagccttctt ggtataaaga actatcgcaa agtataatcc
     4921 gctgagtaca aaagaaagtg tcgtctacta tttctctaag ttgtttacaa atgatattac
     4981 taatagaaaa gtgttctccc aaaatgtctt ctaactgttg tcgatagtat aaatacctaa
     5041 agtctgacgg agctactatg aacacttcaa ttggagattt ccgtttatgc tcatttaaaa
     5101 gacttaaact aatggttagt ttacgaatag aattctcatt ccaacgcaga aataaattgt
     5161 tttgttttcg ccattgttca agaatttcat gaacttctaa gtacaaagcg cgttgctctt
     5221 catttaacaa gtaagtctta tcaggttgaa atatctgaat atcagcccaa agtgagcgga
     5281 taaacgggag aagtgcttta tcaaaaagta tctgattttc ttcagatata ttcagagata
     5341 agataagttt ttgactgagc tcaatcacca aagggttatc tgctacatgg ttttgataaa
     5401 caacgttcaa gtctttttgt aacaattcaa agttatcgca tagataattt ctagagttga
     5461 atagaaagta gatataaagg cattcatctt cgtcatgaca taaagagaaa gaaagttgct
     5521 ctaatccttt ctgtattagc tgaaacaagg gagtatgtcg ggcaactctt ttttcttcct
     5581 gactaaaata tattgggtta gtcttagatc tctgcaaacc gatagcgata cctaataaaa
     5641 taaattgttt ttcaactgta gggtaacttc ttgaaaaaaa tgtttttcta cataatcaat
     5701 caattgttga ccgctttgaa taattgattt atttagctgg atcaactctg tccgatttgt
     5761 ctcatagatt atcgttagta acaaacttcg ataatccttt tcaggaattt caaaatggcc
     5821 atcagcattt aagtactgca tttgtttaaa aaaattaatc aactcatttc gtaagttgta
     5881 aactttgctt aacgaaatga aggtagtatc agctatatta ctccaattgt gttcccctga
     5941 taaataatgt cctagtacat tgaaaaagtc agagcgctga tagatgagtt gagtgagtgc
     6001 caacctcgaa aacgaagagt cgaatgcgac tgtaaagcta cttctagatt tctccactga
     6061 aataatttgc tgatggagta tgtcggtaat gcattccaag tcgttagtga cagtgagtgg
     6121 gcaaacgttc aattgatctg ctatttcgcg aatctgaatg gtcccttttt cgtgtaattg
     6181 ctcacaaatg taaacttgac gaaaaatact tttctccaga taggtttcca acatagtact
     6241 cctcctagtc attttataca taactattat aactctacca atcggaatag tcctgtaata
     6301 tattgaatca aaaatataaa ttataaaata attagatggg gta
//
LOCUS       DAZAOD010000123         6303 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000123 DAZAOD010000000
VERSION     DAZAOD010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.125"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            334..714
                     /locus_tag="ACHDPO_002604"
     CDS             334..714
                     /locus_tag="ACHDPO_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFN3370169.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            696..1610
                     /locus_tag="ACHDPO_002605"
     CDS             696..1610
                     /locus_tag="ACHDPO_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFN3370170.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     TLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPNHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKTEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYTQFCDSLKTFGIHCLNRGKNFTYELVHKKK
                     KVRSNKLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTFTP
                     EQSEIRPTRRNHEQHVERGTDHQQELSL"
     gene            1855..2544
                     /locus_tag="ACHDPO_002606"
     CDS             1855..2544
                     /locus_tag="ACHDPO_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370171.1"
                     /translation="MAFYLPYLLISASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLV
                     GVIFALSIVLSGLFGVLEGNKRVSRSILLGDITQKYEAACDKKKKEQALAQKMEEFTA
                     CYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEKYEQVKKDVQYFKDTQT
                     EEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATNIQNPTKKETALNYLES
                     VKEWLDQQQQN"
     gene            complement(2665..2751)
                     /locus_tag="ACHDPO_002607"
     CDS             complement(2665..2751)
                     /locus_tag="ACHDPO_002607"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFN3370172.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            3427..4377
                     /locus_tag="ACHDPO_002608"
     CDS             3427..4377
                     /locus_tag="ACHDPO_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFN3370173.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            4398..4931
                     /locus_tag="ACHDPO_002609"
     CDS             4398..4931
                     /locus_tag="ACHDPO_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFN3370174.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            4947..5117
                     /locus_tag="ACHDPO_002610"
     CDS             4947..5117
                     /locus_tag="ACHDPO_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370175.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            5567..6100
                     /locus_tag="ACHDPO_002611"
     CDS             5567..6100
                     /locus_tag="ACHDPO_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370176.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            6112..>6303
                     /locus_tag="ACHDPO_002612"
     CDS             6112..>6303
                     /locus_tag="ACHDPO_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370177.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKS"
BASE COUNT         2323 a         1102 c         1174 g         1704 t
ORIGIN      
        1 aaaaaaaaat aaatcgatac attttagaag aatagggttg tttgaatatt acaaagcaac
       61 aatttcacct tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct
      121 ttttttgtat tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt
      181 gacaagcggt tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca
      241 aaccctttta gtgagcttta ctcattgtac ctttttaggt acaatggtat tgcgaacgat
      301 acgtccgtag gacgtactga aagggtggga cttatgagcg aacaacatca aaatttggct
      361 agcgatcatt ctaaaaaata tacctatcga tccgagccaa aacaaatcag ttttcgagtg
      421 agcgaatccg aatttgcaaa gctgaagcag tcagctgaag ctttgcaaat gagtgtgccg
      481 gctttcgtga aagccaaggc acaaaacgcg cgtctggtga caccgaaagt ggcgccagac
      541 attgcccagg caatcgcgcg cgatttagcc aaagctggag ggaatatcaa tcaaattgcc
      601 aagtggtgca atacacacca acacgacgtt gctcctgatg atgctcaacg tttatccgaa
      661 aacctaaaaa tcatgcaaaa ggagctacaa aagatatggc aacagttaaa gtaagtcgaa
      721 ccacttcatg tagccgagca atcaattacg cagaaccacg agcaaccgtc aaaacaggaa
      781 taaactgtga cattgattat gccaaaagtg aaatgaaaca aatacgcacg ctttatggaa
      841 aagacgatcg tgtacaagca cacttattga ttcagtcctt tcgaccagga gaaattaccg
      901 ctgaaaaagc caatcaacta ggggcagagt atgcgaaaaa aatagcccct aaccaccaaa
      961 tcgcgattta cacacataca gacaaagacc atattcataa tcacattgtc attaactccg
     1021 ttaatcttga aactgggaaa aaatttcaag cccatgggca agcattttta aacaaatgtt
     1081 atgacctaaa tgacgagatt tgtcttgaac atgacttaac aatcacggaa cgaggaaaga
     1141 aaaccgaaaa acgaaccatg tctgaaatta aattaaaaga aaaaaatgaa ccggtttgga
     1201 aagacgaaat tcggtttgcg attgatcaaa caatgaaaaa caaaaaaact cgaacgtata
     1261 cccaattttg tgattcactt aaaacattcg gcattcattg cttgaatcgc ggaaaaaatt
     1321 ttacttacga attggtccac aaaaagaaaa aagtacgatc caacaaacta ggaaaggatt
     1381 acgaaaagga gacgatttta catgagctgg acagacgaga acgaacctac aatcaacaac
     1441 gaaccaacga gctacgaaga gctcgagcta gcattcgcga aactgcagaa gaagtacgaa
     1501 gagaacaacg aacttttacg cctgaacaat cggaaattag accgactcga agaaaccatg
     1561 aacaacacgt tgaacgagga acagaccacc aacaagaatt atcgctctaa aacgttaaaa
     1621 gacatcgaaa acgaaataaa gagacaacgt gcctttcttg cgccttatac ccaagaaagg
     1681 atacaaacta cgatggattc acaagtcaaa aaactccacc aagcgctatt agaccagcga
     1741 aaccaagaac aaaaaaaggc tttaattcaa cgatcgatgg atattcttgc ccccttatgt
     1801 tgcttagtac taacattatt agccttttgg ttggtatggg gagaataaac agacatggca
     1861 ttctatttac cctatctact catttctgcc agtattttag gaattatttg gcttagctat
     1921 aaggcttatc aaacaagata ttcattaaaa ggctctaaaa ttcgatttaa gcgattttta
     1981 ttggtcgggg ttatatttgc cttatcaatc gttttaagtg gtttattcgg cgttttagag
     2041 ggtaataaac gtgtttcaag aagcatttta ttaggggata tcactcaaaa gtatgaagca
     2101 gcatgtgata aaaagaaaaa agagcaagca ttagcacaaa aaatggagga atttaccgct
     2161 tgttatgagg acatgaacaa tatttttgtg gatcaagaga aacgtttaac agataaaaac
     2221 atgaaaaaac tcactcgttt ttatcaaaac ttaccagaaa aacagcaaaa agaggtacaa
     2281 gaaaaatatg agcaagtaaa aaaagacgtg caatatttta aagatacgca gacagaagaa
     2341 gcttgttgta acttatttag cgatacaatc cctttttcaa ccagtgaaca agaacgaaaa
     2401 gaacggcaac aatcggtcac atacgaacgt tatgaaacac tgcttcagca agcaacaaac
     2461 atacaaaatc caacgaaaaa agaaacggca ttaaattatc tagaaagtgt caaggaatgg
     2521 ttggatcagc aacaacaaaa ttgaatttga ttagcaatca tgttaaactg aacctgcaaa
     2581 tgatcaaaca ttagatacac gaaagcccca gagaggtcgg attctctggg gctttttttc
     2641 aggttgatgt cgcctttatt gattttactt cttgtttcgg ttattcaacc aataactgaa
     2701 taaagagaca caaacttcta caagaagggg gcaaatgaac cgttcaaaca ttagatacac
     2761 ctccttccag tcgcaagact gtcggatagg cgacaagtta ttatacctta caaaataaaa
     2821 tctgtgtggt gtttttaagt atcccttatt ttcgggttgt tagggcttgc cctgaccgcc
     2881 tgtaaggcgc tttaagaaca agataaggtt ttttacccaa gactgtctta aaacgactta
     2941 gacgagctat cagaggcttc ccccacctcc gttactgact tgtttttagc aaaggagcct
     3001 ttaggcgact gcgcagtaca atgtgagagc atagcgatca cactttttta gcgaccgtag
     3061 ggagcaaggt tttgaattgg cagttttgaa aaatgcgcga acctgttggt agaaaaaaga
     3121 agtggttttt aggcgggaaa ttttgtcacc ctcttttata atctcttttt aaaccttttt
     3181 ttaaacctct ttaccgtcgg ctgtgtcctt actccttcaa tggatacagc gttttataaa
     3241 ctacattttg tctgctttta aactacattt tgtctgcttt taaactacat tttgtctgct
     3301 tttaaactac attttgtctg cttttaaact ctttttttgc actcacgtat gttataatat
     3361 gcattatcac agacaaaacg ttgtttataa cgtctgtatc cattgaagga gtaaggagga
     3421 atatctttgg caaatgaaat cgtgaaatac catcatgaat taaataccat tccgttgcgg
     3481 aaatttacac cagttgaaat gaatctattt ttctctattg tgtctagaat gcgcgaaaaa
     3541 ggcgataaaa cagtccgtct tacttttgac caactaaaag atttaagtaa ttataaagca
     3601 actgctaata atcgtttcat taatgattta gaaatgactt atgataaatt aatggattta
     3661 cgttttggta aaagaagtgc taatgggctc gatatagata gattcgttat gtttagtgag
     3721 tttaaaatac gtggaactgc taaagatcca tatgtagaca tacaagttta cgaaaaagct
     3781 ttacctttac taaacaattt agatgagtgg gttcgctatt cactccaaca atttaacgaa
     3841 ttacaaagta gctatgcaaa gactatgttt cgattactaa aacaatatcg aactaaaggt
     3901 tttgcttatt tttctaaaga ggattttcat gaactattag atattccaaa aagttactgg
     3961 aacaaccaag caaacgttga taatcgtgtt ataaagccta tacgacagga attaaccgca
     4021 atcttcaaag gattatcaat caaaaagaaa tacggaaaag ggcgaggaaa acctgtcgtt
     4081 ggctatcaat ttacgtttaa accagaaatc aaaaaagcag atgattttaa taaacatgca
     4141 ccaaccaaag aagaacaaaa taaagcattg gctttagctg ataaacaaaa agaatacgaa
     4201 gaacctgcta caacaattaa cgaaaaaatc aaacagaaga aacgagaact tgaactcctc
     4261 caacaaatca aacaactaga aaaagagaaa gaagctcttg aaaaacaaac agagtccgca
     4321 ctttcgaaaa aagagaaaaa aagtttatta tctgatttag ataatttatt ccagtagcaa
     4381 cctaggaggc aaccagtatg caaccacaag aaacctttac aataaaggaa ttgtcagaac
     4441 tttttaagat gagtaggcaa gcaatatcga aacatatcca aaaattagat tcttccatga
     4501 tagctaaaaa tgagcgtggt tataaggttg tattgcgttc tggagtattg caacttgctc
     4561 gcaacttagg caaccaaatg ttgctagata ggttgcacga gtacgaacaa gacaacgata
     4621 aaaatgttaa tataccaagc aaaaacgtgg ttacaaacaa gttgctagat cagttgcgtg
     4681 aagaaaatga atttttacga gaacaacttg ccctcagaga gcaaaataat tctcatatac
     4741 aaaaactact cgaccagcaa caacaactca ccctacaagc caacaaacaa atcgaaaaac
     4801 tgcaagaaaa actacagttg acttatacag aagaagctcc agagaatgac tcaacgactc
     4861 tttctgaagc aacagaaaca atagacaaac aaattgatac tgaaaaaaaa tggtggcaac
     4921 tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc ggttctattt
     4981 tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa gggaataaac
     5041 atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa ttgtttgtaa
     5101 aagaaacaga taaataataa aaaagactgc tctttcgagc agccagttaa aaaataatga
     5161 gtgtttattc ttgaaaaagc aacgcgctta tgaagcgcta ccaaaaattt atcatatttt
     5221 attaaaaata acaacccagt aaaaaatgac tggtaaaaat tcacaaagaa acggaaagaa
     5281 gcaaccgcag aaaatcaagc ttaaaaagag cttttgacct agaccaatcg aaaatcacaa
     5341 agtgagcgcc tgtatctatt gctacaggcg ctacttggca tagtgtacat tatgtcaaca
     5401 agaatttaat ataacatatt ttcctaatgc attctaacta taccacatta tcaaaaatat
     5461 aaattatctt tactaaataa aatattgaca agcctatacc ttttgtttta tgattttcac
     5521 aaagaaaacg ttttctatat atttttctgt atcaggagga aattctatga aaaaatttac
     5581 tttaggggta gctttgttaa ctattggggc agttgtttta ccgtcaacta ctatagttta
     5641 tgcttcagaa aattcccaag tggtatcatt aaacgaaaac aatgctactg aaaatgtagt
     5701 tattgagtac actgaagatg gtatggtcgt aactaaatat gaggatggtt atagtgcgga
     5761 agattttgca aattcttcag atatcatgac aagagctgca gttgcaagat ggggcaaaaa
     5821 ggaatataca aatattgctg taaccactgg agtagctgct aatgctatta atgctgcctt
     5881 ttgggcagga gggaaagcta gcacttctat gtttggtatc ccaggttggg caattggtgc
     5941 tttgttaaca ggtgcaagtt ggactaaaaa aggtgcttct ccagggaatg cagttgcaaa
     6001 agaatgggac aaaaatggta atggctggat tggattttat taccaaaggg gatatgatgc
     6061 agctggaaga gttgtagcta ctagatattc aacgttataa gttaaggagt gatgtttttg
     6121 atatctaaat cattaaaatc attaaaaaca tttactaaaa agaatccgca aatagctact
     6181 attcgtattt ttatatttgc tatagctgtt gctataattg ttaatatgct aagcggaggg
     6241 caattataca aatctggttt atttttagtg ttaatcttag ttgtcttaga cataataaag
     6301 tct
//
LOCUS       DAZAOD010000124         6285 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000124 DAZAOD010000000
VERSION     DAZAOD010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.126"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(41..229)
                     /gene="rpmB"
                     /locus_tag="ACHDPO_002613"
     CDS             complement(41..229)
                     /gene="rpmB"
                     /locus_tag="ACHDPO_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFN3370178.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="ACHDPO_002614"
     CDS             499..861
                     /locus_tag="ACHDPO_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFN3370179.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="ACHDPO_002615"
     CDS             913..2595
                     /locus_tag="ACHDPO_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFN3370180.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="ACHDPO_002616"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="ACHDPO_002616"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFN3370181.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEGSEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="ACHDPO_002617"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="ACHDPO_002617"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFN3370182.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="ACHDPO_002618"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="ACHDPO_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFN3370183.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
BASE COUNT         2087 a         1093 c         1434 g         1671 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaaggatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttg
//
LOCUS       DAZAOD010000125         6224 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000125 DAZAOD010000000
VERSION     DAZAOD010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.127"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(207..1169)
                     /locus_tag="ACHDPO_002619"
     CDS             complement(207..1169)
                     /locus_tag="ACHDPO_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3370184.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="ACHDPO_002620"
     CDS             complement(1171..2610)
                     /locus_tag="ACHDPO_002620"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFN3370185.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="ACHDPO_002621"
     CDS             2795..4741
                     /locus_tag="ACHDPO_002621"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFN3370186.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /gene="scrK"
                     /locus_tag="ACHDPO_002622"
     CDS             5005..5877
                     /gene="scrK"
                     /locus_tag="ACHDPO_002622"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFN3370187.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1986 a         1061 c         1107 g         2070 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaggc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 aggttctgtt gcaaagtttt aaatctacta tcagataagg tagaataata gaaaaagata
     6181 gcaggaggaa tgacgatgag tcattttaaa ggaaagcaat ttca
//
LOCUS       DAZAOD010000126         6173 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000126 DAZAOD010000000
VERSION     DAZAOD010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.128"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            725..811
                     /locus_tag="ACHDPO_002623"
     CDS             725..811
                     /locus_tag="ACHDPO_002623"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFN3370188.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACHDPO_002624"
     CDS             complement(932..1621)
                     /locus_tag="ACHDPO_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370189.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="ACHDPO_002625"
     CDS             complement(1866..2780)
                     /locus_tag="ACHDPO_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFN3370190.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACHDPO_002626"
     CDS             complement(2762..3142)
                     /locus_tag="ACHDPO_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFN3370191.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACHDPO_002627"
     CDS             complement(3592..3879)
                     /locus_tag="ACHDPO_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFN3370192.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACHDPO_002628"
     CDS             complement(3899..4123)
                     /locus_tag="ACHDPO_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFN3370193.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACHDPO_002629"
     CDS             complement(4578..4748)
                     /locus_tag="ACHDPO_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370194.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACHDPO_002630"
     CDS             complement(4763..5296)
                     /locus_tag="ACHDPO_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFN3370195.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACHDPO_002631"
     CDS             complement(5317..>6173)
                     /locus_tag="ACHDPO_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFN3370196.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAZAOD010000127         6098 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000127 DAZAOD010000000
VERSION     DAZAOD010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.129"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            277..1062
                     /locus_tag="ACHDPO_002632"
     CDS             277..1062
                     /locus_tag="ACHDPO_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFN3370197.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1075..1926
                     /locus_tag="ACHDPO_002633"
     CDS             1075..1926
                     /locus_tag="ACHDPO_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFN3370198.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2050..2502)
                     /locus_tag="ACHDPO_002634"
     CDS             complement(2050..2502)
                     /locus_tag="ACHDPO_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370199.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(2967..3335)
                     /locus_tag="ACHDPO_002635"
     CDS             complement(2967..3335)
                     /locus_tag="ACHDPO_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFN3370200.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3485..3967
                     /locus_tag="ACHDPO_002636"
     CDS             3485..3967
                     /locus_tag="ACHDPO_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFN3370201.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4004..5014
                     /locus_tag="ACHDPO_002637"
     CDS             4004..5014
                     /locus_tag="ACHDPO_002637"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFN3370202.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5129..5842)
                     /locus_tag="ACHDPO_002638"
     CDS             complement(5129..5842)
                     /locus_tag="ACHDPO_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370203.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2021 a          994 c         1214 g         1869 t
ORIGIN      
        1 aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcacaa aaatttgaga
       61 agtaattttt gtaaattact tcttatttct tgaagctggc cacttctgtc acaacctctt
      121 tctttataga aataaaagga cactagcaat tcatgaaaac gattgctaaa gcgtatcatt
      181 tgctttagac tatatatctt ggtgtacact cactttaaga cggaaataaa agttatccgt
      241 aataacaggt ttaggtatga aaaaggagtg ggtactatgt ataaggaatt agaaaacaaa
      301 gtcgcagtag taactggtgg ctcaaagggg attggaacag cgattgctca acgattcggg
      361 aaagaaaaaa tgaatgtagt tgtcaactat aactcggata aagaaggagc agaaaaagca
      421 gtcaaagcaa tcgaagaggc aggcggaaaa gcagtctctg tacaagcaga tgtcagttct
      481 gaagaaggaa tacagcgttt acttgatacg gctttagaaa attttgggac actggacgtt
      541 tggattaata atgctgggat ggaaaatcag catccaaccc atgaacttag ccttgaagat
      601 tgggaaagag tattaaaagt caatttgact ggcgttttta tcggaacgaa agcggcttta
      661 aattacttta cagagaatga taaaaaagga aatatcatca atatgtcttc tgttcatgaa
      721 caaatcccat ggccaacgtt tgctcattac gctgcttcaa aaggcggagt aaaactattc
      781 accgaaacgg tagcaatgga gtacgcacca aagggaatca gaatcaatag tataggacct
      841 ggtgctatcc gtacacctat taatgcggca aaatttgatg atcctgaaca aaaagaactc
      901 ttggaaagta tgatcccact aggacgcgta ggtgaaccaa aagaaatagc ggcgacagct
      961 gcatggttgg cttcagacga atccagttat gttacaggta ttacactatt tgcagatggt
     1021 gggatgactt tatatccttc tttccaaggt ggaaaaggat aagggtgaat aaaaatgggt
     1081 ttattgattg cattgatccc ggcagttggg tgggggatcc agccactgat tttgaaaaag
     1141 attggtggca gaccaacaaa tgagatatta ggaactggta ttggagccgt gctcgttggc
     1201 ttacttgttc aattattcgc ttctccagct ggtatttcag tgactacatt tttgattagt
     1261 ttactttctg gtgcattctg ggtcatcgga caaacaggac agtatacatc tttcaacttg
     1321 attggtgttt ctaaaacgat gccaatttcg actgcattac agttagtcgg aacctcattg
     1381 attggtgtct tcgcttttgg agaatggtct ggaagtatgg gaaaaatcat tggtgcagca
     1441 gcaatcattc ttcttgtatt tggttctgct ttaacggcaa tcagtgatga tcctggaaaa
     1501 aaaggcggta tcacaaaagg aatcagtcta ttagcatcaa caagtattgg ttattgggtt
     1561 tacagtgcat tgcccaaact agttgatgca agcggacttt ccattttctt tccgcaaatg
     1621 atcggtgtct ttttaggggc agtgatttat gtgattttcc gaaaaccaac cgcattttct
     1681 gaagacaaga gttggaaagc aacaatagtt ggagccatct tcagtgtgtc agcattggct
     1741 tatatttttt cagcaaatga aaatggggtt gctactgcat atatcattac acagctaaac
     1801 gtagttatct ctacattagg cggtatgtac atcctgcatg aaaataagac accaaaagaa
     1861 aaaaaattaa cgattatcgg attattgctg atcgtagtag gaagcatggt cacggtcttt
     1921 atttgaggat aaagatggta aaatctcatt tattaaaaaa atatttgttt gaaccaaaca
     1981 gtaagtactt ataaaaaaat agcgctagaa tttccaacat ctctggaatt tctagcgctt
     2041 tttaattgtt taagatacaa gtgaaatatc tgtctgcatc aataattttt cattgatcca
     2101 ttgactaaaa tttacgacat gattgaagtt accaccgatt agtatctccg catgattgtc
     2161 tttataaaga tcgtattgta aaagacggtc ttttttattt gcgtaaacat cgttatggta
     2221 ctggactaat tgttctcgga tttgattgat tgctgtaaaa tcacgatact gaaggttgaa
     2281 acgcatcgtg attggtgcat ttagcatgaa tcgctgcatt tcttttgctg cttcctctgc
     2341 ttgatctccg tataggaact caaaaagatt acgttcagaa aatttccatt gcccgccaac
     2401 ctttgttcct tttagttttc cttcatgaag ataatttctg atagaacgtg tagtaacacc
     2461 taattgttcg gctaattcat ttactgagta aaaatctttc aatgttcacc ctcctatgtg
     2521 aatggttcta ctgacttagt tgatatttgc ttaatcacga aatgtagaaa gaacgatttt
     2581 aattaaggtc attgtaaaaa tcaagtcaga aaattctaac ttttctttct ctaaagaaat
     2641 tcgttctctc ctaaagtgat attatattta aatatacctg aaaataatgg gcagtattat
     2701 gaaagatcac tgatattttc tcgtattttt tccttattca aaagttttgc aggaaaattg
     2761 ctgaaaaaat aattttacta agtggaaaat tcaaagccat tcaatcagtg atttttttca
     2821 gcacaagaaa gactccttat aaaaatagca gatactttgt caattaagtg tttaaccagg
     2881 gatgataaaa aggataggat tgaacaaaac ctgtataagc tgatgaatag tttcctcgcc
     2941 agtaaaaggt ttattcgtat aaagctttat cgccaaaatt tatcatgacc ttttttatct
     3001 tcaatattaa atgaaatcaa ttgttcaatc aattcccagt tgattacact tttccaagga
     3061 actttgatga cgttatccgt atatacgtag cctgcttctt ggatattttt ttcaagggca
     3121 cgaatcgctg ctttttccgg tgcgatagaa aaatgatttt tagcaaaact aaatgcaata
     3181 ataaaggtac catggtcagt aaacataggt tggttccatt ttacagttgt gtctagctgg
     3241 ggatacgttt ctgttatctt agcaaaaagg tctttgatct tttgttgatg ttctttttct
     3301 ttgatctgat tgatgatcgg ctgaaatttt tccattctaa aacgcctcca ttaagtggtt
     3361 tgatttattt taccagaaaa acaatagtta tgtataaaaa acgaacaaaa cacaagtaat
     3421 gttgtaaccg ctatatttat atgataagat gtctcaaata ataaaataga aaagagacat
     3481 aaaaatgatt gacttggcaa agaaattctt acacgaaaat atatattttg agttgtatca
     3541 tcatcgagcc atttatacaa atgaagatgc tttggtaata aagaaagaac aaggatttac
     3601 aggtacagag accaaaagct tattcttaaa agataaaaaa gataataact acgtatatct
     3661 gacttttact acgaaacaaa cggatttcaa agcattaggg aagatcgtcg gtaaaaggct
     3721 ttctattgtt tcatcagaac gcatggaaga acaaacggga caaaagcagg gcgctgtttc
     3781 tccgtttggt tatgaaaaac agattccgat tattattgat gaagagctct tatcaaatga
     3841 aaaacttgtt tttgcaccag gtagaccaga tcaaacgatg gtcatccaaa cggttgactt
     3901 aaacaaaatc atccagctac ttgagatgcc gatatttttg atgccggcaa acgaaaaaaa
     3961 caattaacca agtaaaatag tgcatacttg gaggtgaagc aacatgataa gttatccatt
     4021 attagaaaga aatgcaacga ttggggttac tgcaccatcc tcaggcgtat cagaggaaca
     4081 ccattcgtta ctcgaatcag ctttaaagag aatggaagaa aaatctttcc aagtagttac
     4141 tggaaagacg ctttggacgc aagataagga aaaatcaggt ccagcaagaa aacgagcaga
     4201 tgaattcaat caaatgatgc aagatgaaaa tatccaaatg atctttccgc cttggggagg
     4261 agaattattg attgagattc tcgattttgt cgattttgat gctctacaac caaaatggat
     4321 agtaggttat tcagatatta gtacgttgct acttgctgtc acattaaaaa cagggatagc
     4381 cactgcacat ggaaccaacc ttattgattt aagaggagag tacttggatg aaacgacagc
     4441 aatgtgggaa agtgtactga aaacaagaga aggagaatcg attctacagc aaccttctga
     4501 aaagtatcaa aaagagtggc cccatgagca ttcatcatct tctgttttcc atctcactga
     4561 accaacaaat tggcaatcag tcagcggaga tgcagtaagg atgaagggac gattattagg
     4621 tggctgtatt gatacgatca gtcatttaat cggtacccct tatggagatg tccaatcttt
     4681 taaaagaaag tataatgatg gaaagccgat cttgtggttt ctagaaaatt gtgagctatc
     4741 gtcagttgat ttaagaagat cacttgttca gatgaaactg gcaggatggt ttgatggcag
     4801 ctcggggatc atgttcggta gaagtgcagc agaggatttg ttagattata aaatgaagga
     4861 tgtatatgaa gatctgtcaa aggaattaaa actaccgatc ttgtatgata ttgattgtgg
     4921 tcatgtaccg ccacaactga cattgatcaa tggtgcctat gcagaagtag cggtagaaga
     4981 tagaaaagcg actgttttgc aaacgtttat ttaaaaaatt ttttcctgcc ttggagttta
     5041 tcaaagacca acaaatctaa atagaaaaga aaatgaaaga agctgacagt attttgccag
     5101 cttctttttg tatgatctat tagaaatttt aattatccat aactatcaca ttgatcagct
     5161 gtttcacatc atttggatta cctgtaggaa tagctactac agatgcatta tcaataattt
     5221 cttgagttgt ttctctaatg aacgctggat aagatgtttg atctgcaggc atttgccaat
     5281 gtgaaggaac tggataacta gtgattgtcc cgtcatggtt acttgaatac actaaaactc
     5341 cctggtaact gtatttccca gtgagcataa ccacatcttt cggatagact gcactccctg
     5401 catcataagg ggcgataggt gttcctgcag gataatgaat aacatgtagt tcgaaatcac
     5461 ccgatgtatc tctaaaagta ttacctctaa ttgctagcca aacacgtgcg tactcaattt
     5521 gtagatcaga atatcctgct aacggatcta ttgactgaga agactgtgag gaagttgtgt
     5581 ctattgttga agaagaaata tttgtctcaa ctgtactact agatgtagaa gaagtattgg
     5641 gctctgagac tttactgctt gttgaagatg tattcgtttc agtagaagct gatttctgag
     5701 tacttgattt ttcagctgaa ctggtttgtt tgattgaact tttgtctgtg gtcgcagatg
     5761 gatcactatt ttctttacta ggagacgtac atcctacaag gaataaagag accaacaata
     5821 aaataaaacc taactttttc atataaaata cctcattatt tttttaatac cagtatagca
     5881 taatcctgaa tttttgaatc cgtaaaacct tgtctatgga taggctacaa ttaactagac
     5941 agaaaaatta aggtgtgtag actagaagaa aacataccag gaggaatttt tatgtctaag
     6001 agaacacgaa gaactttttc acaagaattc aagcaacaaa tcgtcaatct ttacttagct
     6061 ggaaagccac gtgtagaaat cattcgagaa tatgaact
//
LOCUS       DAZAOD010000128         5954 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000128 DAZAOD010000000
VERSION     DAZAOD010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.130"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            59..415
                     /locus_tag="ACHDPO_002639"
     CDS             59..415
                     /locus_tag="ACHDPO_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFN3370204.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            405..671
                     /locus_tag="ACHDPO_002640"
     CDS             405..671
                     /locus_tag="ACHDPO_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3370205.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            830..1831
                     /locus_tag="ACHDPO_002641"
     CDS             830..1831
                     /locus_tag="ACHDPO_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HFN3370206.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(2201..2815)
                     /locus_tag="ACHDPO_002642"
                     /pseudo
     CDS             complement(2201..2815)
                     /locus_tag="ACHDPO_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            3055..3300
                     /locus_tag="ACHDPO_002643"
     CDS             3055..3300
                     /locus_tag="ACHDPO_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370207.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            3398..3619
                     /locus_tag="ACHDPO_002644"
     CDS             3398..3619
                     /locus_tag="ACHDPO_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370208.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            3941..4621
                     /locus_tag="ACHDPO_002645"
                     /pseudo
     CDS             3941..4621
                     /locus_tag="ACHDPO_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
     gene            4761..5300
                     /locus_tag="ACHDPO_002646"
     CDS             4761..5300
                     /locus_tag="ACHDPO_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370209.1"
                     /translation="MWSLVGIVLIIFTVTAATEANYSHKIQSYKGRLVMTKKDVTRYT
                     SSRTGGLYDYAPLDALKYKDHLKKHEVKVGDRWENASHKAYNSKIVYTVEDADEQNIT
                     LPVFNYWGTVVKVNGKKSTIENDNGLVSIKGTGKRTIVEVSSTYPTTMILSLLISSIT
                     FIFLFTRYLIRCCGEMKID"
BASE COUNT         2192 a          819 c         1067 g         1876 t
ORIGIN      
        1 aattcgaatt tttatgttat atactataat ataaaatcaa tatatgatat aattgggtat
       61 ggaaaaaata tcttttgaaa catttaaaag acctaatggt catgatgaat ttttagaatg
      121 gttggaaaca ttaccaaaaa aagatagtgc gaagctttta cgtacaatag aagaaacaga
      181 aaagaatggg atgctagtag ctcaacggtt gaaatgggtg aaaaaattag acactaattt
      241 gtacgaatta agaagtaagg taggatcaaa catccaaaga gctatctatt tccatgtggt
      301 caatggaagg tatgtcatta cccatggatt tactaaaaaa acggagaaaa caccaataag
      361 tgaacttaaa catgcaaaag aacttagaga ggagtggttc acaaatgatg attaaaaaat
      421 tgattgaaga aaagcaaaaa gacaaagatt ttgcagaagc atatgaccgt gaaggaagaa
      481 aactcgaaac tgcggttgct ctttatcatg cacgggagga agcaggccta actcaagcgg
      541 agcttgcaca aaaagcacat acaactcaat ctactattgc tcgaattgag agaggggata
      601 acgtatcttt cgataaactt gatgatatcg ctagggcatt aggcaaaaag ctggtagtag
      661 aatttgctta aaagcgagtt gaaaatatac ctgtaatagg ctcctaacta atcaattagt
      721 ttagtgggcc tttttgtact aaatagataa aagttgtcct atagtgtaaa agtcaataaa
      781 ttttatacaa aaattacttt aaagagacat aaagagaaag gtacaataaa tgaaaaccat
      841 aaatctaata aaagtattta tagcatcacc aggtgatata gcagcaaaga ggaatgaagt
      901 agaagaaacc atatatagat ggaatataga aaatacagat aatacaaaag taattttgat
      961 gccaattcga tgggaaacga atgcgattcc tacttatata aataatagct ctgggcaaag
     1021 tgttattaat aaacaaattg tagaaaatag tgatatatta ttagcgattt ttggccataa
     1081 gttgggttct ccagttgata attatagatc gggaactata gcagaaattg attactttta
     1141 taaaaatagc aaaggcgagg taggggtttt tttcttagat gaaccagttc cacaagtttt
     1201 ggctgaagag tatatagaag ttaagaagta cagggactct ttagaagata agggttttta
     1261 tggaacatat agcaaagaca atatcagaag gtttctcaca aaaaaagtga attatttaat
     1321 tgagaaagca caaaataatt tagaatcaaa acgctttgat ttagattcta tttcttacaa
     1381 gacaccttca gtaattaaca aaaaagttac cggaactgat aaagattttg atgacaactt
     1441 agatattttt gatccaatag aatttgacaa tgatgaaaga ttgctgctaa tatatgcgtt
     1501 tatggatgaa aattctatct tttcaactga taattcaact tatagaaaag tagttcaatg
     1561 ggaaagtgat aacaatttaa ggagttactt gagtgataga gtatttgatg tactagaaaa
     1621 attaagtaaa tcgggaattt taaaggaaga atacgattct tcttttgatg agtatccatc
     1681 acgctatatt ttgatttcag aggactataa gaaatttaaa aggtattttt taaaaaatga
     1741 aaaaaagata tctgttatta tggagaaata caaagctcca atacaggctg atccattttc
     1801 caatttggat gaatcagatt taccgtttta aattttaaat agataatttc attttttagt
     1861 agcagaggta taaacttttt taatgtttga attgaaaaga aatgctaata ggtcgacttt
     1921 atgtttctct tgtgcaatcg taaatgcggg ggaccataaa attgatctat tatcgagtgt
     1981 gtataaaata aaattcaaat cttattagtt tacataagat acattatact aagttgtcaa
     2041 tgttaaatgc ctttaaataa ggacgattta tgcatcaatt atatttatgt taactaaatt
     2101 ctttttaaca taaatgtaat caacttagct agatgaatct aaaatgattg tctgtattga
     2161 tgacaaagct aattaataat tacgtgattc aaaaaagaaa tcatacaatt agttggtcga
     2221 tttctttttt tattcggtaa attgtttgcc tagtcacatt gtagtctgtt gcaatctttg
     2281 agatagcaac cccattctca agatcctgaa cgatactcct atagacaagg cgacgttgag
     2341 gatctttggt gtctgcactg tataacttag gacgaccttt atagacgccg tttgctttag
     2401 cgattttaat tccttgtgcc tggcgtcgtt tcgattcagt acgttcttgt tcagcaatca
     2461 tggctgagat ttaaatgatt aagtctttga tgaatttatc taggagagga tttccaattg
     2521 cttcagccat gatcggtaaa ctggtgataa taagtcgcac attcttcttc tttagataat
     2581 tcactgaatc gataatctcg tcataattgc gtccaagtcg atcaatggct tctacaataa
     2641 aaatatcttg ctctctgaca aaatctaaag cttcctggaa aatcggccga tgactaatcg
     2701 tcgctccaga ttgtttttcg ataaaaattt tttcagcgcc aaactttttc atttcttcaa
     2761 tttgacgttg ttcattttga tcgatggatg aaactctaat ataagcaatt ttcaaattta
     2821 ttccctactt ttctataacg tttataatac accctaatca tacgttagaa ctctaaattt
     2881 ttcaatgtta tatttttgtc tatttagggt aaactctaaa tagacaaacg gtttttgaat
     2941 tctaaaagtt aaatagttta taatagaaga aaaagaatgg ggtgacgatt tcttagattg
     3001 aaaaggaaag ataaatatta tagattatta cttttgacag ctgaagcagg atggatggat
     3061 tttccagaag ttgtaaaaga agttcaagag ataggtgcaa ctatttctga tagccgctcc
     3121 tctcctatga actatcagga tgcccatgga attaaaataa ttgatcaaga gagaaatgtc
     3181 agaaaataca caacaataaa tgagtgtgta attaatgaaa atctttgtag ggcaccgata
     3241 acgaaacaca ttaagaatag aagcaaagca aaagacggaa gaacttttac taccttctaa
     3301 gtttttttca tatttgtttg ctatacttag atctaaggaa ttagactttc gctgcccatt
     3361 atttaagttt gaggtagcgt cttgcgaggg atcaataatg gaagaagaaa aaatatttga
     3421 aaaacgctgg gaattggctt cagttgaaca aagagcaagg taccataatc taatgtcctc
     3481 ttaccgtaat attgattgga cttacaaaga aaagaagtac ttgctttggt tatgtcagtt
     3541 agatgtaaat acctttgaaa catttgaagt gattctagat aagattaaaa acagcaatga
     3601 aaaaagagct gatctataat ggttcgctct ttttatttta ttaactcttt ggttactata
     3661 tgtaaaatac agcttcatat tacaataaat ttcaggatac aaatttattt aagcatatat
     3721 aaatataatt gaaataggac ataaatatat gagtatgaga aaggtgattc catgtttaat
     3781 aaatgggcaa accacccaat gaactcgaga ggtagagata atttgaagga gacggacaag
     3841 ttctgggaag aagtatatag taaaaacggt tctgttgcaa agttttccaa aaaatctatt
     3901 ttagtgtaaa attgagaaaa aagacagaga ggacagagta atgaatcatt ttaaaggcaa
     3961 acaattcaaa aaagacgtca ttattgtcgc tgttggttac tacctgcgtt acaatctaag
     4021 ctatcgtgaa gttcaggaat tgttatatga tcgtggaata aatgtttgtc atactacgat
     4081 ttatcgttgg gtataagagt acagcaaagt cctctattat ctttggaaga agaaaaatag
     4141 acaatccttc tattcatgga aaatggacga aacctatatc aaaattaagg gacgttggca
     4201 ttatctttat cgtgcaattg atgcggacgg cttaacctta gatatctggt tacgaaagaa
     4261 acgggatacg caagcagcct atgctttctt aaaacgactc cataaacagt ttggtgagcc
     4321 gaaagcaatt gtgaccgata aagcaccttc tcttggctcc gcctttagaa agttacagag
     4381 tgtgggttta tatactaaga cagagcaccg aactgtgaag tatcttaaca atttaataga
     4441 acaagaccat cgacctatta aacgacgaaa taaattttat caaagtctcc gtacagcctc
     4501 ttccacgatt aagggcatgg agaccattcg aggaatatat aaaaagaacc gaagaaatgg
     4561 aacgctcttc ggcttttcgg tgtctactga aatcaaggta ttaatgggaa taacagccta
     4621 agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca gaaccgagaa
     4681 ccttgggttt tcaagtgctt tttggttcat taatcttaac catagtgttt ttaaagtgga
     4741 aaacaagcaa caaaaaaagt atgtggagcc ttgtaggaat agttcttatt atttttactg
     4801 tgactgcagc aacagaagca aattattcgc ataaaattca gtcgtataaa ggtcgtttag
     4861 ttatgaccaa aaaagatgtt acacgttata catcctcaag aactggaggc ctatatgact
     4921 atgcaccatt agatgcattg aaatataaag atcatttaaa gaaacatgaa gtaaaagttg
     4981 gtgatcggtg ggagaatgca tctcataaag catataattc caaaatagtc tatacagtag
     5041 aagatgccga tgagcaaaat atcacattac ctgtattcaa ttattgggga acagttgtga
     5101 aagtaaatgg gaaaaagagc actatagaaa atgacaatgg tttagtgtct attaaaggta
     5161 cggggaaaag aactatagtt gaggtttcat ctacgtatcc aactacgatg attctatctt
     5221 tattaattag ttcaataact tttatattct tatttacacg ttatttaata agatgctgcg
     5281 gtgaaatgaa aatagattag atagatatta taaatatgtt gattctattt tcatagcaat
     5341 ggagaaaata cattagcaat atataaaaga aggtatcaag agtcacagtg aatttattcc
     5401 gaaaagtgaa aagagcaaat ataaaattta atgaaaatat agaactaaat aggaaaacgt
     5461 agacgtaatt ttctacgttt tccttttcat atatattaaa tattacggaa aattatataa
     5521 actaatttag tgttttgttt gtaattccta attttgctcc acttttagat aatttttagg
     5581 tctatttaac tcatcagaca ttctatgctc atttttctcc aaatttgttt caactctttc
     5641 gtacttaatt ttgcgtattt gaaaattctt cttttagagt acttttatta cgatactagt
     5701 atgatatata tctatagcaa acagttaaaa tcttcctaaa ataagcgaat agcattccta
     5761 aaacctataa aatttttaga tgaagcgaca agtggacaat taataaacta cttgaacatg
     5821 aaattatgga tcacctttca aatttagaaa atggaattct tatacttatt gcgcaacatt
     5881 tattgattgc aaaattatgt gacaaaaaaa actagtagaa gaaagaataa tggcttgata
     5941 ataaagtact acct
//
LOCUS       DAZAOD010000129         5870 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000129 DAZAOD010000000
VERSION     DAZAOD010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.131"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            86..1717
                     /locus_tag="ACHDPO_002647"
     CDS             86..1717
                     /locus_tag="ACHDPO_002647"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFN3370210.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            1720..2799
                     /gene="uxuA"
                     /locus_tag="ACHDPO_002648"
     CDS             1720..2799
                     /gene="uxuA"
                     /locus_tag="ACHDPO_002648"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFN3370211.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            2873..4300
                     /gene="uxaC"
                     /locus_tag="ACHDPO_002649"
     CDS             2873..4300
                     /gene="uxaC"
                     /locus_tag="ACHDPO_002649"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFN3370212.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            4384..5031
                     /locus_tag="ACHDPO_002650"
     CDS             4384..5031
                     /locus_tag="ACHDPO_002650"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFN3370213.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            5151..>5870
                     /locus_tag="ACHDPO_002651"
     CDS             5151..>5870
                     /locus_tag="ACHDPO_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3370214.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRAL"
BASE COUNT         2009 a          798 c         1227 g         1836 t
ORIGIN      
        1 tcccttttta tattgacaac ggttacaatg ggttttaaaa tataaaatgt atcaaaacta
       61 acatatcagt ttgaggaggt taattatggt ttcgattaaa aattggcaaa attctatcga
      121 agaattcaat gaaatgcaga ttctactgcc gtgttttgat gtcaaagaag ttaagcaaga
      181 aggccagcaa catccagtat ggcttcattt tggtggagga aatctttatc gaggatttca
      241 tgcagaaatt gctcaatgct tagcagatca aaatgaatta gaaacaggag tagttgtgtg
      301 tgaaacattt gatgaagaag tagtggaaaa agcttatcat gactataaca atgacatttt
      361 ggaaattgtt atgagtggag atggtgaact caaaaaaaga cttttggcag taacggctga
      421 tagtttatat tgcaatccga agaatatagc ggactatcaa agagtggtta aatattttga
      481 agatcctaaa ttacagttta caacgtttac tattactgaa aaaggttaca gtttaaaaga
      541 ttctaaaggg caattctttt cggtagtcaa agctgatatc aaatctggac ctagcaatcc
      601 tcaacatacg atgagtattg taacatcctt gttatatagc agatttaatg ctggagagtt
      661 gccgattgcg atggtttcta ctgataattt ctcacagaat ggtcaacgtt ttcaagatag
      721 tatttttacg attgcagaag cttggcaaaa agaaggatat gtttctgaaa aatttattgc
      781 ttatttaaag gataaagaaa aagtgacttt tccttggagt atgattgatc gaattacgcc
      841 aaatccttca gagaatgtaa aggaagatct attgatgatg gggctcgagg atttagatat
      901 cattcacaca aaaaaacata ccaatattgc tgctttcact aatactgagg tagttcatta
      961 tttagttatt gaagatagtt ttccaaatgg ccggcctaaa ttggaaaagg ctggtgtgat
     1021 tatgacagat agagagacgg ttgataaagc agacatcatg aaggttacga caagcttgaa
     1081 tccacttcat actgctttgg cagtaacagg ttgtctgcta ggatatcaat caatttcagc
     1141 agagatgcag gatgatgatt tggttggttt aatcaaagga ataggttatt tagaaggttt
     1201 accagtagtt gaaaatccag gcattattga tccaaaacaa tttattgatg aagtaattaa
     1261 taaacgtttg cctaatccct atattccaga tacaccacaa cgaattgcaa cagatacttc
     1321 tcaaaaagta gcgattcgct atggtgaaac aattaaaaag tatgtcgaaa aagacggaaa
     1381 tgcagaaaat ctaacattta ttcctatcgc tattgctgct tggttacgtt atttactggc
     1441 agtcgatgat caaggggaaa attttgtgcc aagtcctgat ccgttattgg tagagttgca
     1501 ggataaatta tcagtattga aattaggtga acaagatcct tcaaagattc attgtgcggt
     1561 acaggaaatt ttagaaaata aagaaatctt tggtttagat ttatatcaag ttggggtagg
     1621 aaagaaaact gaaaaaatct tttgcgaaat gctagtaggt cctcaagcag ttcgtaaaac
     1681 aatcaataaa tatataacag aagttggagg aaagtaacta tggaaatgac ttttagatgg
     1741 tatggggcaa atgaagaaaa aatctcacta caagaaattc gtcagatccc agcaatgaaa
     1801 ggaattgttg gaacattaat ggatatacca gccggagagg tttggccgag agaacgaatt
     1861 aaatctttaa aagatgaagt cgaagccaat ggacttacct tgaaagttat tgagagtgtt
     1921 aatgttcatg atgatatcaa aattggttta ccaacacgag atcaatacat tgagaattat
     1981 aaacagacga ttcgcaattt ggcagaattt gggattgagg ttatctgtta taattttatg
     2041 ccagtatttg attgggtaaa atcggatttg gattatcgtt tagatgatgg gtcttctacg
     2101 ttagcctata tttcaaaaaa tatccctact gatccggagg aaattattag agaagtagaa
     2161 aattctacta ataattttga attgccgggt tgggaacctc atcggttatc acaaattaag
     2221 caattattag aagcctataa agaagttgat gaagagaaat tacgagagaa ctttgcatat
     2281 tttctcaaag caattatccc gacatgtgaa gaagttggga ttaaaatggc agttcaccca
     2341 gatgatccac catattccat tttcggatta cctcgtattg ttaaaaatcg tgacgattta
     2401 gattggttgt gtaatgtagt ggattctcct tctaatggta ttacattatg tactggaagt
     2461 attgcagaac gaccagataa tgatgtctat gaaattctat ctgaattttg tcaacgggat
     2521 cggattcctt ttgcacatgt tcgtaatatc aaatatttaa gtgacaatgg actcgatttt
     2581 tacgaagcgc cgcataaatc agaatatggt tctctagata tgtataagat attaaaaaca
     2641 atgtacgata atggatttaa tggctatatt cgtccagatc atggtcggat gatttgggga
     2701 gaaaccggta gacctggtta tggattatat gaccgagctc taggtgcagt ttatttaaat
     2761 ggtatttggg aagcgcttga aaagggggcg agtaaataat tatataaggg agtttattta
     2821 gaggaaaaat tttctcttct aaaaactaac ggaaggaaag gagtgtttaa atatgttttt
     2881 agataagaac tttttattag agaatgaaat agctaaaaga ctttttcata aatttgcaaa
     2941 acaccaacca attatcgact atcattgtca tttagaccca gcatatttgc tagaaaataa
     3001 gcaatacaag aatttgactc aggtatggtt aaatgataaa ggagctggag atcattataa
     3061 atggcgattg atgcgagcta atggtataga agaagagttg atcagtggtc caggtgatga
     3121 ttatgaaaaa tttttagctt ttgtaaaaac agtggagaag gcgccaggta atcctatttt
     3181 tgaatggtct catttggaat tacaacgtta ctttgatatt gatttgacaa tttctgagaa
     3241 gaatgcacca gaaatttggc gacgtgctaa cgaaaaaatt caaacggatt cctatcgccc
     3301 gaaagaattg ttggagatga tggatgtgaa agccatctgt acaacggatg atcctacaga
     3361 tgacttgtgg tatcatactg agctttctaa acaggataat tctttcaagg tattacctac
     3421 tttccgtcca gataaggtct ggagtatcaa atcatcaggc ttttcgaact atattttaaa
     3481 acttagtcaa acagcggcta taccaatcaa agactttaat gggttgaagc aagcattgag
     3541 ccaacgagtg gatcattttc atcaaattgg ctgtcgatta gcagatcacg gtttgaatac
     3601 ttatttttat gaaatagcag atgaaaaaat actcgacaat ctgttaataa aagctttagc
     3661 aggaaaaacg gatttccatt tatcagaaat tgcacaattt gttacaggta ttcaattaca
     3721 tttgatgtct gagtatacaa gatatggttg gacgatgcaa atgcatttaa atgctttaag
     3781 aaataattca agtatattaa aggaacaaat tggagtagat gtcggtggtg attcgatggg
     3841 ggatcaagct agtttgacac aaaatgttgt agcattgttc gataccgctg aaaagagtgg
     3901 gtgcttacca aaaacaattt tatattcatt aaatccaact gattggcttc cactagcaac
     3961 agcaatgcaa agcttccaag ggggtatgat tcaaaaaatc caattgggat gtgcttggtg
     4021 gttcaatgat acagctgaag gaatgcgtca acagttgact acgatggcac aacaaagttt
     4081 gttgtcgaat tttacaggta tgttgactga ttctcgaagt tttctaagct atcctcgcca
     4141 tgagtatttt cgtcgagtat tatgtcaatt actaagcgag tgggttaaag caggccgaat
     4201 tccagatgat gaaatgtatc ttagtcagat agtggagaat atttgttatc gtaatgcgta
     4261 taattatttt aatttttttg aaatcggaag tagaaaataa tacttgaaat aaaagcttaa
     4321 atttattctt tgtaagttag tacagctaga caaagtatgt atccataaag gaaggagata
     4381 gatatgaaaa aagtagaaat tttaagtaag ttagaagcgg ctggagtcat tgcggttgta
     4441 cgtgggaaaa ataaggatga ggccattaaa gcaataaatt caattattgc gggtggaatt
     4501 aaagggattg aactaacttt tacagttcct aatgctgaag aaataatcaa agaaattgct
     4561 aaaaaatatg ctgatcaaaa agatgtaata atcggagccg gtacggtttt agatgcgttt
     4621 actgctcgta tcgcaattat ggctggggca gaatatatcg ttagtccatc ttttgatcga
     4681 caaacagctg agatttgtaa tttatatcaa attccttatt taccaggttg tatgacaatt
     4741 actgagataa aggaggcact tactgctggc gtagatatca ttaaactatt cccaggttct
     4801 gcttttggtc catccattgt aaaagcctat caagctccat taccacacgt aaatataatg
     4861 cctactggcg gagtaagtat agagaactta gaagattggt ttgaagtagg agttgttgca
     4921 gttggtgtag gtgggaattt attggcttct gttgaaaaag gtgattttga agaagtaagt
     4981 cgagtagcta gtaaatatat agataagttt tatgagataa agaattatta ggagaaaaaa
     5041 caaataatac tctgaaatgt aaaaaataaa tactgactct ttacgcttca gagtatagta
     5101 cgtactttca tcagaatgaa aacgcttaac aacagaaggg agagaattgt atggaaagaa
     5161 aatttggtat aagagacaaa ataggatata tgtttggaga ttttggaaac gattttactt
     5221 tcatttttgc tagttctttt ttaatgatct tttatacaaa agtattgggg ataagcggag
     5281 ctgccgttgg aacattattt ttagtagcaa gatttatcga tgcagttact gatgtaacta
     5341 tggggcgtat tgttgataga tcgaaagcaa ctaagcaggg taagtttaaa ccgtggattt
     5401 taagaatgag tggtccagtc gctttagcaa gttttttaat gtatcaaact tctatgattt
     5461 cagcttctat gagcgttaag gtagtataca tgtatgttac gtatatatta tgggggagta
     5521 ttttttacac atctataaat attccttatg gatcaatggc atcagctatt acttctatta
     5581 cagaagaaag aacaatgcta tcgacattcc gaaatgttgg agctacttta gcaagtttgg
     5641 tcattggtgt attaacacca ttatttattt atacaagaga tgattcaggc gctcaaatag
     5701 ttcgtggtgg atcaactttt acaattgttg cgggaatatt ttcgatatgt gcacttattt
     5761 gttatttaat atgttataaa ctaactactg aacgagtaag aattgaccaa tctcaataca
     5821 aagtttcatt gttaaaatct ttaaaagggt tagttaaaaa tagggcatta
//
LOCUS       DAZAOD010000130         5754 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000130 DAZAOD010000000
VERSION     DAZAOD010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.132"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..157)
                     /locus_tag="ACHDPO_002652"
     CDS             complement(<1..157)
                     /locus_tag="ACHDPO_002652"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370215.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEV"
     gene            complement(151..552)
                     /locus_tag="ACHDPO_002653"
     CDS             complement(151..552)
                     /locus_tag="ACHDPO_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFN3370216.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(739..2547)
                     /gene="uidA"
                     /locus_tag="ACHDPO_002654"
     CDS             complement(739..2547)
                     /gene="uidA"
                     /locus_tag="ACHDPO_002654"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HFN3370217.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(2570..4336)
                     /locus_tag="ACHDPO_002655"
     CDS             complement(2570..4336)
                     /locus_tag="ACHDPO_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HFN3370218.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(4349..5143)
                     /locus_tag="ACHDPO_002656"
     CDS             complement(4349..5143)
                     /locus_tag="ACHDPO_002656"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFN3370219.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(5153..>5754)
                     /locus_tag="ACHDPO_002657"
     CDS             complement(5153..>5754)
                     /locus_tag="ACHDPO_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3370220.1"
                     /translation="MNNYVFPDYYNDAQGIVLMNFINPILVLIVVSPLTLFLSKKYGK
                     KELASVGMFFSAIVYLILFLIKASNMYVFLILSSVGYMGLGVFNTVIWANITDVIDDQ
                     EVKSDQREDGTVYAVYSFARKIGQALAGGVGGWTLSIIGYDSLANVQTGDVLEKLYNA
                     STLIPSICFLIVGLILFFLYPLSKDKVLENCELLKQKHK"
BASE COUNT         1841 a         1140 c          699 g         2074 t
ORIGIN      
        1 ctacctcgtt aaatccattt gtcaaacata acttagccat ataagaatga taatgtttga
       61 gtatcatctt gatcgaaatt ggatctcctt ctagagcaga taagataatg gatagtggaa
      121 ctaataggta ctgccgcttt ttagatttat ctaccatagg tcatacccca ttttcaattg
      181 ttcaactgcc ttctttcgtt gataccagat accacttgtg ctcatattga gaattttacc
      241 gatttcagca tcattaaaac ctgcaaaata ataaagtagg ataatctttc ttcttatctc
      301 cgataactga tcaattgctg ctgataactt ttgatctgaa attaatattt ccattccaaa
      361 taagaaatag acatcttgtt catcaaaatg agtttgggaa tacctgcctt catttgaatc
      421 tgccaatggt tcctcattat cctttatgtt agcgtttcgt tttcgaatag acttagcttc
      481 gtttcgtaat acttttttac agtaggcatc aaattggtgt tgtatagata tgtcattgta
      541 atgttgttgc atgataatat gctccttttt ccccctttcc actaatacaa caatcagaaa
      601 gccccttttt ttcgaaaaaa ctagaaaaaa aacataaaaa tatttatcat tctttaaaca
      661 gaaaatcttt ctataaaaaa caaaaaaaaa cgattaggct aggctaatcg ttttttgaac
      721 attcttaaaa aatccaaatt attttttata actgaaattg ggtattgatg accatcgttt
      781 ctgtagatag taagcaatca ttttaggttt tctatctcta gtaaagattc ctttcttatt
      841 tccttgcact cttaaaatcc cttgacttgt tgcaaaatct gcaaaattcc acacttgttc
      901 accaacaaaa ttttcacatg tatctattac ttcgtgattt gcttcgtaat aagccacttg
      961 atactcttct gtaaacattg ttggtactgt atcatgaaat ccagctactg tatctgctcc
     1021 atattctgta aacattattg gcgtatcagg acatctttcc atccatccat ctagctcttt
     1081 tttcaacaga tattttgcat gtgccagatc ccctcccgaa acataccaac cataataacg
     1141 atttaaacat aaaacatcga caatatctcc taccttacaa acatctggcg ttgattttag
     1201 ataagtaacg attgttacag gtcttttctg cggatcaagt tctttagtta attcaactaa
     1261 aggttcaaaa tattctttag caccttcgga atccgaatct ggttcatttg caatagacca
     1321 cattacaaca cttgggtggt tcttgtcgcg ttctatcaat tccttgatca ccgttttatg
     1381 agaattttct gttcgtatct ctttccacgt attatgtttt tccacattat catctaataa
     1441 agtggccatg aaatttaaat gtaaccctac tgcaggtact tcatcaataa ctacaatacc
     1501 ttctcgatct gctaatcgca taatttcttc tgagtaagga taatgtgatg ttctaaaaga
     1561 attagcacct atccatttca ttaaattaaa atctttaata tttacagcct cattcaaacc
     1621 acgtccatta acatacgaat cctcatgctt accaaatcct ttaaaataaa aaggtttatt
     1681 attaatcaaa aatttgccat tggtaacctg aacactgcga ataccaaatt cttctgtata
     1741 ggtatcgatc actttattat catcaattaa actaattttc atactatata aataagcgtc
     1801 tagaggttcc caaaaaattg gattcttaag ctgaatcatt cctttctttc cttcagcttc
     1861 agctacaagt tgagcctctt cgtcatatat cgctattaag atttttccgg tccattctgt
     1921 atcgatattg aattctacac ttgcatccaa atcagttatt cttgtattaa tagtaatatc
     1981 acttatatag tctttcggag ttgtatataa cttaacaggt ctatgaatac ctgcataatt
     2041 gaagaaatca aaattaacta agttttcctt ttttatatcc ccattttcct gtactgtttc
     2101 cttcataatc cccacaggta aagtactatc gtcaataata ttgtttacag caactgtaat
     2161 tcgattattc ccgtctttta caaaccgatt aatttcagac tcaaatggtg taaacccacc
     2221 tttgtgttga gtaataaact ttccattcaa aaaaactttt gcttcatgtg ttgcagatcc
     2281 aaaacgaaga actaatcttt cttctaataa tcttttagga agagtcactt ctttttcata
     2341 ccacacccat ccaacatgat ttctaatgtt ctctgtttca aataaatcat tataagaaga
     2401 gggaactgaa atcggataac tctctttttc atttattggt tctaaagcaa gttcttcctg
     2461 taagtcatca tttgtatcta atttaaatct ccagagaccg cttaagtcaa ttacttgcct
     2521 cgtctctgtc ataatgggat acaacatata aaccactcct atctaaatat taaataaatg
     2581 tatcctttaa accacaataa gcatctattg gacttactcc cttaaattca gaaagaccca
     2641 ttagtttgtc caccaatatt tctaaagttt cttgttttcc atcataagta ttaatataag
     2701 tctttacttg aggtacatca gccaaatgaa acggacactg tacagataca aaaattgttg
     2761 gaatttcatg aatgtaaaac ggtatatccg gagttccttt acttgctggc cagacaattc
     2821 gttgaactgt gcctggatta acattagcta tattaatgat caagtcatat tttttagtta
     2881 aatttttaat tggtctctta gcagcatata ttccagctat atttttaatt ttttcttctt
     2941 gcgataatcc tttcaattct tcttcaggtg aaatgtattt ttcaacttca aatccttttg
     3001 ctgacaaaat ctgtttcaat aaatcaatgg cttgaggtct atttccagca actacttcac
     3061 caaacccacc ttttacccca tgtacatcta ctagtaaaat ccttttatat ttttctggta
     3121 caataggcca aatatcttgt ttatctttaa ctaatgtaat tgcttggtca gccacctctt
     3181 taaaaattga tttattttca attaaaccaa ttttttccag agcttcttgc ttaggtaata
     3241 aaatttgttc ttttgctttt ttgtgtaatc ccaatttagc ttttaaccct aaaattcttt
     3301 ttaaggcatc taataaccga tcatcagtga taattccttt acgatagcct tccatcatat
     3361 aattaaagtc ttcatctgga tcattaaaaa atagaaatag atcacatcca gctgcaatag
     3421 aagtgggcaa taattctgat cgtttcattg ccccagtcat tcctaacata tgactagcat
     3481 cagtaactac taatccatta aatccgagtt ttcctctaag taagtcagtg attaattctt
     3541 ttgataaagt tgcaggaagt aaatcttcat ctttcagatc aggattaaaa tgttttgaat
     3601 aagctggcat atggatatga cctgccataa ttgaaggtaa tccagcttct attaagcctg
     3661 agtatacttt tccaaaagaa ttatcccatt cttccgtacc taaactatta atactaaaag
     3721 atagatgctg atctcgttcg tcaataccgt caccagggaa atgtttagct gcaggcaaaa
     3781 ttccactctc ctgaatacct ttcatataag ctaaactaag ttctaaaact ttatcagggt
     3841 tttgtccaaa agatcgacta gaaatgatag gatttctcca atttctatta atatctacaa
     3901 taggagcaaa actccagtta catccaatag ccgatgcttc aatcccagaa actctcccta
     3961 attcataagc atatttcgca tcatttgttg caccaatttt tacttctaca ccaacttcag
     4021 taccatctgt acaagctccg ttaccacctg cttccgtatt agcagcaatt aatagaggaa
     4081 ttttactttc tgtttgtaag atatagtttt gatcatatac ctcatcagca gttcctggat
     4141 tatatcgtac agctccaata tggtactgat tgaccatatt actcaagtaa tttttatcac
     4201 gactagatcc catattaaca aacaattgac ctattttttc ttccaaagtc atagaatcaa
     4261 tcgtctcttc aatccaagaa atagcatctt catctaaatt atatggtttt tttcgtaaat
     4321 ctacttttat agtcattttc tttctcctct acttattagt aagatttttc caaaaagtat
     4381 ctatatattt ttgttcaata tctacataat ctcccgataa acatttaaat aaaacatcag
     4441 ttcttaagtt ttcccatgat tctttttctt tattgaccaa aataggataa aagaaaactt
     4501 tatttttatt tgcagcttct agatcaccag gagaatcacc aatcattaat atcttatcca
     4561 aatcacaacc attttcaatt acacttcgaa taatatcttc tttttttcct ttatcttgac
     4621 aacacagttc atcaactaat gataataatt catgtctttc ccattcttct tgaacagctt
     4681 ccttattagc tgagcttaca ataattatct tcccatattt tttcagagct tttatagtat
     4741 ctctagcact taaaaagggt ttatctaatc cttttgcttg actaatctgt tgattgactt
     4801 cttccgacca ttttaaagct tttaataaat cctctgactg agaatattct atttccctct
     4861 tcaaagatgg attagacaat tcttttgtta gagataccca gtgctttaat cgattaatcg
     4921 atgttacatc atttttttct aatgttttaa ctaaacctaa aaatctgttt attccacgag
     4981 tctctgaata taaattaata ttattccaat cctgtaggaa tttttctcta tgatgaacat
     5041 caaaaatctc tgcagcaatt ggtccgaaaa agagattgtg tttataagtc atcgtatcca
     5101 taacacagcc atctgaatca atacaaaata tccaattatt catatttctc tcctatttat
     5161 gtttttgttt taaaagctcg caattttcta agactttatc tttagataat ggataaagga
     5221 aaaataaaat taatcctaca atcagaaaac aaattgatgg aattaatgtt gaagcgttat
     5281 ataacttttc taaaacatct cccgtttgta catttgctaa agagtcatag cctataatag
     5341 aaagagtcca acctccgacg cctccagcta gagcttgacc tatttttcta gcaaaagaat
     5401 ataccgcata tacggtccca tcttctcttt gatcagactt tacttcttga tcatcaataa
     5461 catcagtaat atttgcccaa ataacagtat taaacacacc caaacccata tagccaaccg
     5521 aactaagaat taagaataca tacatattac tagcttttat caaaaataag atcaaatata
     5581 ctattgctga aaagaacatt cctactgatg ccagttcttt ttttccatat tttttactta
     5641 aaaacaaagt taaaggcgaa acaactatta aaaccaaaat aggattgata aaattcatta
     5701 aaactattcc ctgtgcatca ttatagtaat caggaaatac ataattattc atac
//
LOCUS       DAZAOD010000131         5727 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000131 DAZAOD010000000
VERSION     DAZAOD010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.133"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            196..921
                     /locus_tag="ACHDPO_002658"
     CDS             196..921
                     /locus_tag="ACHDPO_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370221.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGFSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="ACHDPO_002659"
     CDS             911..1420
                     /locus_tag="ACHDPO_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370222.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="ACHDPO_002660"
     CDS             complement(1490..2938)
                     /locus_tag="ACHDPO_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3370223.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="ACHDPO_002661"
     CDS             complement(2938..3654)
                     /locus_tag="ACHDPO_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFN3370224.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="ACHDPO_002662"
     CDS             complement(3635..3985)
                     /locus_tag="ACHDPO_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFN3370225.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="ACHDPO_002663"
     CDS             4129..4902
                     /locus_tag="ACHDPO_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFN3370226.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="ACHDPO_002664"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="ACHDPO_002664"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1662 a         1123 c          994 g         1948 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tttttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt tttttta
//
LOCUS       DAZAOD010000132         5589 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000132 DAZAOD010000000
VERSION     DAZAOD010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.134"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..377
                     /locus_tag="ACHDPO_002665"
     CDS             <1..377
                     /locus_tag="ACHDPO_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HFN3370227.1"
                     /translation="KDAISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEI
                     VPQNVSKGVVFDRLESIYNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKA
                     DYVTVSNDKDGVSQAFERILTI"
     gene            658..1878
                     /locus_tag="ACHDPO_002666"
     CDS             658..1878
                     /locus_tag="ACHDPO_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFN3370228.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            1875..4595
                     /locus_tag="ACHDPO_002667"
     CDS             1875..4595
                     /locus_tag="ACHDPO_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3370229.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            4579..5523
                     /locus_tag="ACHDPO_002668"
     CDS             4579..5523
                     /locus_tag="ACHDPO_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFN3370230.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2076 a          899 c         1101 g         1513 t
ORIGIN      
        1 aaaaggatgc tatcagcatt tacaaatttt ttatttttat tcctaatcgt caattgaaag
       61 ctaatatatt taaccatttg aaaaagatgc taaatgtgtc tgttactgaa tcggcacctg
      121 taaatattga aatcgtacct caaaatgtat ctaaaggtgt ggtgtttgat cgtttggaat
      181 caatctacaa tttaaagaaa cctttgagaa tcgcgatcgg agatagttta aatgacttat
      241 ctatgtttga aagtgcagat attagttttg caatgggaaa tagtcatcaa gaaatcatga
      301 aaaaagctga ttatgtcact gtttcaaatg ataaagacgg agtatctcaa gcatttgaaa
      361 gaattcttac catataaact aattaaggta gtatagaaca tagaattcta aatacggaaa
      421 aatggagcat aaattccagt acaaatagta cttcttcagt gtcaaacgaa gcgaatataa
      481 catagatatt taggattgtg acaaaaatca tgtcacaatc tttttttcga ataaacttat
      541 tttttgaagt cggccattta tcgtaatttc tttgcataat acgaacaaat tttcggttat
      601 tgatgaaaaa aaacattgaa aatggtatga taaaagaaaa aaaggaggaa atttttaatg
      661 gtgaaattta tccatgcggc agatttacat atggatcggt catttgaagg actgacaact
      721 cttgataaaa ctgtacagga aaaactattg aagacgaatc tgaccgtttt atcaaatatc
      781 attgaacagg caataataaa taacgttgat tttgttttac ttgcaggaga taattttcat
      841 caaaatcgtc cttcattaaa aatacagaaa catttttcag aacagatgaa acggttagaa
      901 aagaaccata tacctgtatt tataatattc ggaaatcatg atttctatca aaaagagcgg
      961 tattggttct cctttcctaa aaatgtccat ttatttacat ccgaaacggt agagacaaaa
     1021 aaaataacga taaaaagtgg agaaactgtc tctctcagtg gatttagtta tcgtcaaccg
     1081 tggattcaaa aagacaaagt gatggaattt ccttctagag aactcacaga ttaccatatt
     1141 gggttgtacc acggggaacc tggcgtctct caaaaaggaa actatgctcc tttccaaccc
     1201 tcaaagatgc aagaaaaggg atacgattat tgggctttag ggcatatcca tgtgccaacg
     1261 gtcttaaatg aaaagcaaac aattgtttat ccaggtgcgc ctcaaggtca tactaaaaag
     1321 gaacaagctt ctacatctat tctactagtt gaattaagta aaggaagttg ccaaatacat
     1381 ccgattaaag tagcagaggt ctattggaag acaaaggaaa tatcattgag gaaagcaaga
     1441 acgacaaaag aggtcattgt tcacattcgt cagcagcttt caaaagtaga ggatggattt
     1501 agtttaattg agataaaatt aaaagattat gaccatctca atacagatgt tttggaacgg
     1561 atacaatcag gagagctatt agactatttg ttagaggaat tctcagatag gataaatgat
     1621 ttctttattt ggcgtatttc tctcatagag aatacttttt atacgaagac cccacttgct
     1681 gcttctgcta aattgatgga acagttattt caatactatc agacacctca agatttccaa
     1741 caaattttaa atgaagtata tagtcatcaa gaagcggcta gaatattgag cgaactgccg
     1801 gaatatcaag aagaaacact tgaaaaagcc aagcagctgc ttaatcaaga ttttttattt
     1861 gaggaggatc aggaatgaag attttaagga tcgagattgc tgcttttgga aaatggcgtc
     1921 aaaaaagttt tgacttttat tcaggcaatc agctgatcta tgggggaaac gaagcaggaa
     1981 aatcaacgat ttatcaattt attcaagcaa tattatttgg tttcccttca aaaggccgta
     2041 aaaaaaagga ttatacacca aaagacggct cagcctatgg cggcaaaata tggcttaaac
     2101 atcctgtata tggtgaattt gctgtcgagc gctacaagca gcaaaatcgc ggaaaatcga
     2161 aggtgtggct gggggatcaa gtgggaagtg atgagttact agaaaaactg atcgcacctt
     2221 tgacgaaaga gttattccag caggtattta ctttccagca agagcagttg atggaactag
     2281 atcatttgag agaaaaagag ctacatgatg cgctgatttc tttaggcatc acgggcagtt
     2341 ctcaagtatt ccaaaagcgg caagaatatt atcagaaagc acaacaatta ttcaagaaaa
     2401 aaggccaaaa attactaatc aatcaaaaat taaatgaatg gaaagagctg caagaaaaaa
     2461 ttcatcaaaa acaagaacag gaagcttatt ttggcaagtt gatccaacaa gaacaggaat
     2521 acgagtcgca acagcagcag ttattggcac aattaaaaga ggcgaacaaa caattttcat
     2581 tagccagaca gcaagaactt aatttttctt tatatgaaga atggcaatct ctcaaaaaaa
     2641 acagcactac aggtcttcct gatgagcaac ttcttttaga tctggagtct ttctccaaac
     2701 ggtatcagca aacaaatgag cgtttggaag aattagaagc aacactggaa aagcatagcg
     2761 ggatggatca gcagtcagcc agatattatt tttatttaga gcaggagcag gaactaaaag
     2821 atctccagca acttcaattt acagcggaac aattaaacga agaatggcaa agattacaaa
     2881 ttgagactag agaaacaaat tcagaattga agattttgga acaaaggtgg cattggcaga
     2941 aaaatccgtt accggaagaa tttttatatg aagaagaatg gaagcatctt ctggctgaag
     3001 aaagaaggat tgctgatcta gaaagccaga tttctgtgcg tctccaaata gctaaagaac
     3061 agcaagagat gattgaagca gaagtgaatg acttggaaga gacctatcca gcattattac
     3121 aaaatcagtc agagatagca ccagtctctt catctaaacc gtatatgctg atggctggcg
     3181 gagcaataat cattgcaggt atatttgtac caatgccctt gaaagtgatc cttttactaa
     3241 ttggtgcagg catgattggc tatttcttct acaaaaggca accaaaaatt aaaactaaaa
     3301 atgatttctc tgagataaaa ggaatgtggc aagaaaaact aggacaactt gatctagcct
     3361 tagctcaatt agctgaagca gaagaaaaac aaaagagaac tggagaagaa aaacagattc
     3421 ttcagcaaga agtatatcgt tttgcggatc atcggcactt aggaaagatg gatacgctca
     3481 aactcatgaa agaatatgga caggaagtca tagattatca gaaattatat ggcgtatttg
     3541 agcggaaaca taaaagagaa caggaaatac aagaaaaact acgacaaatc gaccaaaaat
     3601 ttgagtttgt taaagaatgg ttaccgatac aagataagac aatttcagaa aaaatggtat
     3661 tgctttcccg ttttatacaa gagatggaac agatgaaatt tgccagaagc tatcagcaaa
     3721 atactttatt gaagcaagaa atcaatcaat tgaaaaagaa acaaaaagta tggatacaag
     3781 aatacagcga acaattgact caagcaggct tatcttatcc ttcggaagta cctgtctttt
     3841 tacaaaaagc caaacaagcc gaacagcaga tgaaaagata caatgaatta tcggaaatgc
     3901 ttactccact atttcctgaa gagctgacaa aagagaaatt atctgtaaga ctgcgccaac
     3961 tgaaagaaaa gcaatcccaa ctccagcaag aagaaaaaga agcaagtgaa aatcggcaac
     4021 gactccaact tcaagtagaa gagttgcaaa gagacggcac attggacgaa ctttatcaac
     4081 aagctagccg gcaaaaagca aaattacagg aattactgga ggaatgggga gcacttgaaa
     4141 tcgccgggac attcttaggt gatctttcaa cagagatgag tgaaagacaa ttaccccagt
     4201 tgttaagagc agcaggtgat tatttaggta ttttaacaaa aggaaattat cagaagatat
     4261 tactgaaaaa tgatacactg actttaacag acggatatac agaatttccc atctatgagt
     4321 tatctacagg tacgaaagat cagctgatta tggcgatgag atttgcttac ctctcattag
     4381 aagctaaccg ttcgatatgc ccgatcatca ttgatgatgg ctggcttcat tatgatcatc
     4441 agcgaaagta tcaattagct gaacttttag ctaaatttgg agaaaagtat caaataattt
     4501 gtttttcttc tgataaagaa atggtaagct attaccatga gatgaaccaa atcgtaaaac
     4561 aattagaagg agcaaataat gaaaaaaatt cgtgatttag taatcgatga gcagtttgaa
     4621 caatttgtcc tgatcaaaag tgcagatgta agaatcgcta aaaacggaaa aaaatttatt
     4681 gcttttactt tccaagatac ttcaggtact atcgatggta aatactggga tgcttcggag
     4741 gaggaaatca ataaatttac agccggcaca gtcgtttttc taaacggtaa aagagaggtt
     4801 tatcaaggaa accctcaagt aaagattctt catatgcgct taacaagggt agatgagcca
     4861 ggagagccta gtttatacat ggaaagagcc cctttgaaga aagaagaaat ggaagaagaa
     4921 atcaatcaat tgttgtttga gatcaccaat gcgcattgga atcgtattgt tcgctatcta
     4981 cttaataaat atcaaaaaca attttttgag tttccggcag caaaaagaaa ccatcatgca
     5041 tttgccagtg gattagctta tcatactttg acaatgcttc acttagggaa atcaatcgcc
     5101 gatgaatatc ctgagctgaa tcgagcattg ttgtatgctg gtatcatttt gcatgattta
     5161 ggaaaggtga ttgaactttc cggtcctatg tcgacagaat atacgcttgc aggaaatttg
     5221 atcggtcatc tggtattgat tgacgaagaa ataactaaag cctgtcttgc gttgaaaatc
     5281 agcgaagctg acgaagatgt tctcgtatta cgtcatatgg ttttagcaca ccatggctta
     5341 ttagaatatg gctcacctgt acgtccaaga ataatggaag cagaaatatt acatcaaatc
     5401 gacaatatcg atgcttcgat gcagatgatg ttgacttcga ttcgtcaaac agaaccagga
     5461 aaatacaccg atcggatttt cggtatggac aaccgaagtt tctatgtacc aaaagattta
     5521 tagcaaaaat ttattttttt cattcaaaac aaaaaaagcg agacataagt cttcgctttt
     5581 tttgttttc
//
LOCUS       DAZAOD010000133         5370 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000133 DAZAOD010000000
VERSION     DAZAOD010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.135"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..339)
                     /locus_tag="ACHDPO_002669"
     CDS             complement(<1..339)
                     /locus_tag="ACHDPO_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370231.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSL"
     gene            541..840
                     /locus_tag="ACHDPO_002670"
     CDS             541..840
                     /locus_tag="ACHDPO_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370232.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            1105..1980
                     /locus_tag="ACHDPO_002671"
     CDS             1105..1980
                     /locus_tag="ACHDPO_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370233.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            1977..2195
                     /locus_tag="ACHDPO_002672"
     CDS             1977..2195
                     /locus_tag="ACHDPO_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370234.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            2182..4809
                     /locus_tag="ACHDPO_002673"
     CDS             2182..4809
                     /locus_tag="ACHDPO_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFN3370235.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            4824..5042
                     /locus_tag="ACHDPO_002674"
     CDS             4824..5042
                     /locus_tag="ACHDPO_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370236.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
BASE COUNT         2046 a          678 c         1054 g         1592 t
ORIGIN      
        1 tagcgaaaac gtatcactat atctttcttg aatgtcttta aagactttgt gaggtatttc
       61 tgggaagtcc ttaatatata gctcataccc tatatcgata aggtatgaag ttatatattc
      121 ttctaaagtt ccccatttaa tccagtcaat tgttgaatta gtgatagttg ataataattt
      181 cagcttttgt ggatttggta aattggtccc acgttcccag ttggatatgg tcgcacgtgg
      241 tgaattatct attttccttc caagttcttc catagtaaaa ccacatgaaa ggcgtaattg
      301 tttgattcgt tttcctgctt ctgaaggatt tggcttcatc ttttttctcc tttttatttt
      361 taaagatagt atatcatatt tataaaataa aagtatttaa aagtatttac tttttatctg
      421 gagtatgata ctttattctt ataaatacaa ataaatacat ttttttacgc aatttgtatt
      481 tatttgtact tataaaggta gaggagttat agaataatta attaaaaagg agaggttttt
      541 gtggaagcaa taaaattaat gatttcagaa gaacaggagg aaatgtttct aaagcagttt
      601 tatcaaattg ctacaaaagc tattgaaaag gctcaagaaa atgcggggat gacaagggaa
      661 tatctcaatc aaaaagaaat ggcggaatac ttaaatgtga gtgaaaactt tttaaaaaat
      721 gctgtgagaa atgagggatt gcccgtagtt gaattagggg caagaaaatt ttattcgaaa
      781 aaggcagtta atgagtttat gtttgctcga atgaaaagag gggaaaatat tggaagatga
      841 tgaagtagaa attataaaaa aatgctttaa aaaaagaaaa aaagtgttcc caaaagtttg
      901 cagactgggg gaacactcaa taataaagtg ctgagaaaac tttatttata gctattatat
      961 caaaaaagaa ggtgaaaagg tgttttcttc tggaaatgtt gtagttgaca aacttagaga
     1021 aataaatttt gacggaaatg taatccacac acatggtacg atcaattaag aaaaaaaacg
     1081 aaaaaaggtg ttgagaagcc ctatttgaat gcaatagtta tcttagcaga aattacctat
     1141 tggtatagac ctaaaaaaat ttttaacgat gatggtcagc tacttggtta tcaaaaaaag
     1201 tttcttgaag atattttgca aaaatcatat aagcaattaa gcaaaaaaac aggattatca
     1261 gaacgagcta taaaagatgc aattgtgtac ttagagaaaa aggggattat caaaagggtt
     1321 tttagaaata tttattatga gaaaagagca gttacattat caaatgttat gtacattgtt
     1381 ttaaatgtac ataaattgat agaaattact tttcctactt tggattgcga aaaaaaggag
     1441 tatatgccga aaattcgtca gaggggtatc gaaaaaaaga gatatgtctc tttaaaaaaa
     1501 ggtagaggta tgtacaaatt tgtatatacg tatacaaaga ctacttcaca gaacatatca
     1561 aagactactc tcgttatgga agaagaggat attaatataa agaggattta cagtaagatt
     1621 agtgttcttt atgacgcaaa taacgaagat ggtcgaaaat tatttcaagt gtatcactat
     1681 ttgagaaacg ctaatgtaga tacagaagat atcagaaaaa tcattgaata tttatctgaa
     1741 aatactcagt atcttattgc tgagtgtatt ataaaacaac atgaagcatg cttttttcaa
     1801 agaaaaactg aagaagggtt atacgattat gtaacatatt ttttgaatgg acttcagaaa
     1861 agatataaaa gtcaattttt agaaaatgta gagcctatag atcagttcaa aaaagctttc
     1921 gaaatcaaag agttacctga aattactatg cataattggt tgaaaggaga agaatcatga
     1981 ttaaaaatcg cttaatagat caaatgtggt gtcttgatca aaatacagat actctcgaat
     2041 taatcgagag tatctgcttc aacacagtag ttctcgattt aagagctgaa aatgacaatt
     2101 gtgtaactca tatcataatt aatcaaaaaa tggctcagca gctctctgag agcctaagaa
     2161 aatgggctga aggagaaaac tatgaaagca attaaagaaa aaatcgttag tagaaaaata
     2221 aactggttag cactcagtgt acttgtttta atgattagcg ttgtttttac aagtaatatt
     2281 gttgaagcta gcattttcaa ttggtttgat gacacaaaaa gtcaaacaga gtttttgaat
     2341 aattctcttt atagacctta cctaaaaaaa tacaatggag atttccttag tcagttcggg
     2401 atttggcttg gatgggctgt ggtaaaaggc atgtttactg tgactgattc gattcaaaat
     2461 atgattccag atgtgttgga tttgttcaat ttcattgaaa gtacagggct aaataatgtt
     2521 tatcaatcag tcataaatac aattgtcgtt ggattaatga tcctttcatt gatgtttgtt
     2581 ggctacaaga tgattactgg aaaaggaaca atagatttaa gatctgttgg aatgaatata
     2641 gtgatgtctg tagcgttaat tcttttaatg ccaacaatga tttctagcgg tattcaattt
     2701 gccaaaatat tttacaatga tgctactacg attacaaatt cagatgacgg agtcgcttgg
     2761 tcattgataa aacaaggagt aacagatctg gcatatatta ataaaacaga tcaatactca
     2821 agcattgata aaacggagga tcgaaataag ttaacacgaa aaaattttca acagacagat
     2881 ttaacacaag tgttgacgga taaagtgatt gataaattgg aaaaagaaaa tccagctgcg
     2941 gataatcttc gctatgaatt agttgaaaat tctaataatg aatttgttgc cacaaagttt
     3001 tctgataact tcttatcaac attttctgat agcttgaaat caggttatta tcgatatcaa
     3061 gcaaatcttt gggggatttc gattgggttg acagcgttgg caatcgccta tgtgttcagc
     3121 gcgtttgtga tcattacagc aatattagaa cttgcattta aacgtgtgtt aggtgttctt
     3181 gtttttgcga cagatattga aacaggacaa cgttcaaaag ttgttttatc cgatatttta
     3241 caatgttact taacagttgg atttcaaggg tttggactat ctatgtttgc tatgtttatc
     3301 aattttttaa atgctggaca aggtatctcc acaaatattt ttataaaaac aattgcttat
     3361 atctgtgctg tgtttgtgct gataaaaggc agtggaacag tcatgagata ctttggtgtt
     3421 gatattggac tcaaagaagg ctatgggcaa cttgcttctg cttttggtat gggcgcaatg
     3481 ctgtttagaa aaggatcaac tggatttaat cgtgctaaag gaagcggaaa tggaaatgga
     3541 tcagacagtg gagaaggaga agatcgaaaa ccagaaaaga atttcggcga aactctatca
     3601 aaaaaagctg gcaaaactgg aagagctttg ggatatgccc atgaacgtgg attatcaggt
     3661 ttagcttcag atggagctac aatggctagt gaaagagcaa taaaaccatt taagagtatg
     3721 cgtgatatgg ctaatgatac caagaataag ttcaaagaag gtttagatga tggtacagtg
     3781 tccgctatta ataaaaatag caaacctatg ttagctaaaa ataaagaaga tgaaactgga
     3841 aaatatgctg attccatgcc aacacgtctt tcggatagaa aagatggtgc taaggttgaa
     3901 aatgccgata gaattatgtc tagttctgaa cgtatgcgtg aagcaatgaa aaataatgct
     3961 gaatcgaata ataatcctgt aagtgcaatt cagcaaaaag ttcaacaaga tattgaagaa
     4021 cgtaaaaatg ctatgcacgg tcaagctaag tctgctgaag aattaattaa tcagaagcga
     4081 caagaagcta aatacacgcc tgaagcaatg aatcgtgagg aaatgttaag gaaacgtgta
     4141 gaagggcgta caggagctaa tacggacgaa aaagaagcgt tgaccaaaga aagaatccaa
     4201 gaagctaaaa actcaaatac cggattagaa aaattggtca aagaaaatct acaaaattct
     4261 acaagtagtc aaggtggccg atcagtagat gtccgagaaa atattcaagg ttcattgaat
     4321 ggtcatgtcg gacggaatgt tgatgtaaga gagaatttac aaagctcttc aaatggtcaa
     4381 ggtactaaga caattgatgt tcgagaaaat gtacaaaatt ctacaagtag tcaagggttt
     4441 aaatcaatgg atgtaagaga gaatgtacaa aattctacaa gtagtcaagg gtttaaatca
     4501 atggatgtaa gagagaatgt acaaagttct acaagtagtc aaggattcaa aacagtagat
     4561 gttcgggaga acgttcaaaa agatagtgga gaaatgaaag aaaaaacaca aaaaatcaat
     4621 atcgttgaag acagaaagtc agcgaaaaaa tttgattcaa atcatgaaac agtgattatt
     4681 gatagtgaaa tccgtgaaaa tgataaggga tcaaaaccaa gacgaagatt tacctatgaa
     4741 gacaacgagt tattcagaga tacacttaat gatcctaatc cgcttttcga taatctatta
     4801 aaaaaataaa agggggaatt gtcatgaaat taattctaaa gattagtacg catgatttct
     4861 tagaacttga cgaattatgt gaatcagtaa agaacgcaac aaatgaaaaa atcacggtca
     4921 ctaattatat tgaactgatg attcaagaag aattaaagat gaaacatgag ataaaaaaca
     4981 acttgaaata ttgttatcta gaaaaaagtg aagagataat ccatgaatta aatggctttt
     5041 aaaaattgta tttgacatga atttacgaca aggaattagt ggggattaag cgattattct
     5101 cttccacttt agagaaataa tgggttaaaa agccagaata cgtagagcaa tattgacaac
     5161 ctataaagga gctattgttg aaaattgaag taacaaaaag ataaagggag gtttacatct
     5221 atcagattaa aagtgatagt acacccatga aacctgcaaa agagttgaac ctaatgtata
     5281 tcggtttaac tctttttatt tgcaaattaa aaaaatatca ccgaagtgac gaatgaaact
     5341 atgaccaaat taagcaagaa aatatatctt
//
LOCUS       DAZAOD010000134         5275 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000134 DAZAOD010000000
VERSION     DAZAOD010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.136"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..263
                     /locus_tag="ACHDPO_002675"
     CDS             <1..263
                     /locus_tag="ACHDPO_002675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370237.1"
                     /translation="KKKNPAQTSCLFFSNRFAHEINCFSHHRQFIPFTSFNLTATRHK
                     GVIATLSHFAYSSRLRSFVKVKTVVQGAVGIGVKACCSKFLD"
     gene            439..537
                     /locus_tag="ACHDPO_002676"
     CDS             439..537
                     /locus_tag="ACHDPO_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFN3370238.1"
                     /translation="MYEKFLTLVVAPLFVGLVIELVSHWLDEKDDN"
     gene            complement(691..1188)
                     /locus_tag="ACHDPO_002677"
     CDS             complement(691..1188)
                     /locus_tag="ACHDPO_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370239.1"
                     /translation="MKLFFEKMGWHILPVVIILVGSYSLFCIFRSILEKFEEPKLKRV
                     VFALCFAFLALFVSVGISSYRPDVALSVRPKISKIEQLEAKAEAKQKKIDKISDQLEQ
                     ALKIASQEKLKTFNPKDYPSEVITADWVQKNRDVIATLPDKELKDRYTKRFDDVESYF
                     ELNSQ"
     gene            complement(1216..1671)
                     /locus_tag="ACHDPO_002678"
     CDS             complement(1216..1671)
                     /locus_tag="ACHDPO_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370240.1"
                     /translation="MPLDDFASKQELQKVKQELAEIKQQNQEVIETLKSLDNSVKQGY
                     IKVRGGEDIPKMSELKAEMNRYATYVQKRTAEIDQKLDSYGNISKSVSDELSRQVRPQ
                     VQKFLANDDRATAEELKQNRIANLMSVLASVGLFIGGTAILIVSVLKLL"
     gene            complement(1679..2665)
                     /locus_tag="ACHDPO_002679"
     CDS             complement(1679..2665)
                     /locus_tag="ACHDPO_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFN3370241.1"
                     /translation="MGATLALKGGKRGASALIGYVNRHGKLDRDRIYTHKLSAENKLA
                     QTQLEATRRTFAKTGGIQAFHWVQSFDNSFDKNNPADVQKAHEIGAKLVDEIAKSYPN
                     HEIYMGTHTDSESGYIHNHIVFASIDTETGKKFHSDTEVGYHLQDLNDKVLLSFGIEQ
                     PKEKFKQVDFEMHAEGKMSNREKMKHMILGAQDMSTDFDSFKKNLQEAYAVEVYEYNK
                     GKRIGFKWVDDEGKDFTIGGRKLGSDFERPAIERTLEFSQQKQEKEVEKPLETKPKVT
                     NDDFSISGLKNLANDIRQQEERKKKEELQRQKEIERQQRSRPFYHDRGGMER"
     gene            complement(2650..3006)
                     /locus_tag="ACHDPO_002680"
     CDS             complement(2650..3006)
                     /locus_tag="ACHDPO_002680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFN3370242.1"
                     /translation="MSEQKLNAENRKDSRQIKFRVSEDEYQYLTAIADQTGMSVPQLC
                     KSVALGMKYRAPNVDREGAIQIAKELRKYGGNLNQMARFINMNKGQMPSSSDLALMNQ
                     QLSQIEKGLIDLWEQL"
     gene            complement(3562..3927)
                     /locus_tag="ACHDPO_002681"
     CDS             complement(3562..3927)
                     /locus_tag="ACHDPO_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370243.1"
                     /translation="MAKMDIEDLEKKLAEARHDLSVKIGTNMVEKQGFKSYSAYNTFM
                     RNASKALKSSAGSAPAPAAAKPVATSAEKLPSELKAEAVQFQKQLEKWMEDNWGNKLD
                     YKTFYPELLEFFQKLNSLE"
     gene            complement(3936..4097)
                     /locus_tag="ACHDPO_002682"
     CDS             complement(3936..4097)
                     /locus_tag="ACHDPO_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370244.1"
                     /translation="MTAKTVTIDVEQLEKLLERHSDAIIEYTGGLSEETINQFDLLLT
                     EIIELDSKE"
     gene            complement(4087..4236)
                     /locus_tag="ACHDPO_002683"
     CDS             complement(4087..4236)
                     /locus_tag="ACHDPO_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370245.1"
                     /translation="MKKRLRKKMAKKNSSLDQAMKELMNYAKGERDGFLIHSYDEKGE
                     QKNDG"
     gene            complement(4250..4999)
                     /locus_tag="ACHDPO_002684"
     CDS             complement(4250..4999)
                     /locus_tag="ACHDPO_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFN3370246.1"
                     /translation="MGQPNKKADIALKDLLSRQDYLVVQGNDLAKAFGGLKSFEQRVL
                     DYCFSFVTKDSKLDDEYEVTALEIIKHFGLNTSGDSYRRIAEAFKKLNENTALYLRVE
                     RPDGTQGLRMTQLFSWIDFYADGLVRFKFSADSAPYVLDLKEKFYSFRLGELSRINGK
                     YALIMLKLWESYRRGKEKHTTITGDLEEWESWFLGKDKRLPAGQFFQKVITRAIEELS
                     DKMSVSFFVTTLKRGRKVVGYEITINDTSKE"
BASE COUNT         1373 a         1195 c          976 g         1731 t
ORIGIN      
        1 aaaaaaaaaa aaatcccgcc caaaccagtt gtctattttt ttccaacagg ttcgcgcatg
       61 aaataaactg cttctcacat catcgacaat ttatcccctt tacctcgttc aatcttacag
      121 ccacaaggca taaaggagtg atcgctacgc tctcacattt tgcttacagc agtcgcctgc
      181 gctccttcgt taaggtcaaa accgttgttc aaggagcggt tgggataggc gtaaaagctt
      241 gttgtagcaa gtttttagac tgatttagat taaatcgtta gtcttgttat acagcgcctt
      301 tacaggcggt cagggcaagc cctaacgacc caaaagcccc atctggtaga ccatcttttt
      361 tttgcaggga gtgaatgcta tattaatctt ggcactaaag ccaactaacg cttacacagg
      421 ttgggaggtg tattccgtat gtacgaaaaa tttctaacgt tggttgtcgc accgctattt
      481 gtcgggctag tcattgagct agtttctcat tggttggacg agaaagacga caactaaggc
      541 ttagtgcctt ccaactcaca cgcctagtcg cagggcgaaa aaaaagccag acaccgtcgc
      601 atggtgtctg gcttttgtgc attccgcact cgaaaaaatt ctaacgtttt cgcatggtta
      661 ttatagcatg gacgttggca aatctcaatt tcactgacta ttcagctcaa aataggattc
      721 tacatcgtca aatcgctttg tgtagcggtc tttcagctct ttatcgggca aagtagcgat
      781 cacgtcacga tttttttgta cccaatccgc cgtaataact tcgcttggat agtcttttgg
      841 gttaaaggtt ttcagctttt cttgactggc aattttcaat gcctgctcca gttggtccga
      901 aattttatca atttttttct gttttgcttc ggctttcgct tctagttgct ctattttgct
      961 gattttaggg cgtacagaca gcgcaacgtc cggacggtat gaagaaatgc cgaccgacac
     1021 aaaaagcgct agaaacgcaa aacagagggc aaaaacgaca cgtttcagct ttggttcctc
     1081 aaatttttct aagatcgagc gaaaaatgca gaataaacta tacgaaccga ccaaaataat
     1141 cacgacagga agaatatgcc accccatttt ttcaaagaac agtttcattt gcgttttaag
     1201 ccccctctcg ttcgattaca ggagctttag gactgaaaca ataagaatag cagtgccacc
     1261 gataaaaagc cccacagagg ctaatacgga cattaaattc gctattcgat tttgtttcag
     1321 ctcttcggca gtcgctcgat catcgttggc taaaaatttt tggacttgtg ggcgcacttg
     1381 ccggctcaat tcgtcagata cagatttgct gatattaccg tagctatcaa gcttttggtc
     1441 gatttcagcg gttctttttt gaacgtaggt ggcgtagcgg ttcatttcag ctttcagctc
     1501 gctcattttg ggaatatctt cgccacctcg caccttgata tagccttgtt ttacgctgtt
     1561 atcaaggctt ttcagcgttt caatgacttc ttgattttgt tgcttgattt ccgctagttc
     1621 ctgcttcact ttttgaagct cctgcttact tgcaaaatca tctaacggca tatcgtcact
     1681 acctttccat gccaccacga tcatgataga acgggcgaga acgttgttga cgctcgattt
     1741 ctttttgtcg ttgcagctcc tcttttttct tgcgttcttc ttgctgacga atatcattag
     1801 caagattttt caaaccgctg atagaaaagt catcattggt gactttaggc ttggtttcaa
     1861 gcggtttttc gacttctttt tcttgttttt gttgagaaaa ttcaagtgtt cgttcgatcg
     1921 cagggcgctc aaaatcagaa cctaattttc gtccgccgat tgtgaaatct ttgccctcat
     1981 catcgaccca tttgaagcca atccttttgc ctttattgta ctcataaacc tcgacagcat
     2041 aggcttcttg aagatttttt ttgaaagaat caaaatcggt actcatatct tgtgcgccca
     2101 ggatcatatg cttcattttt tctcgattac tcattttgcc ctcggcgtgc atttcaaaat
     2161 caacttgttt gaatttttct ttcggctgtt caatgccaaa actcaataaa accttatcgt
     2221 ttaggtcttg taggtggtag ccgacctcgg tatcagagtg aaatttttta ccggtttcag
     2281 tgtcgatact ggcgaaaaca atgtgattat gaatatagcc ggattctgaa tcggtatgag
     2341 tgcccatgta gatttcatga ttgggatagc tttttgcgat ttcatcaacg agtttagcac
     2401 cgatctcatg cgctttttgc acgtccgccg gattgttttt gtcaaacgaa ttatcaaacg
     2461 attgaaccca atgaaaggct tgaataccgc ctgttttggc gaaagtccgt ctagtcgctt
     2521 ctagctgagt ttgagccaat ttattctcag ctgacagttt gtgcgtataa atgcggtcac
     2581 gatcaagctt tccatgccga tttacatagc caatcagcgc agaagcccca cgtttaccgc
     2641 cttttaaagc taaagttgct cccataagtc aatcaacccc ttttcgattt gcgaaagttg
     2701 ctggttcatc aaggctaaat ctgaacttga aggcatttgc cccttattca tgttaataaa
     2761 gcgagccatc tgattgagat ttccgccata tttgcgcaac tctttggcaa tttgtatcgc
     2821 cccctcccga tcaacgttcg gcgctcgata cttcatgcca agtgccacgc tcttgcagag
     2881 ctgtggcaca ctcataccag tttgatccgc aatggcggtc aaatactggt actcgtcttc
     2941 gctcactcga aatttaattt gccgactatc ttttcgattt tcggcattca atttctgctc
     3001 gctcatctca tcactcctca aataaaaatg ctccctattc ggtcgctttt ttcttctcgt
     3061 cattcttcgt ggtcgatatt caaagctaca aaaacgctcc ctattcagtc gccttttttc
     3121 cgcaatgaaa tctccctcgg ttatgccact acaaaatgaa agttccctac tcggtcactt
     3181 ccctttttcc gctctataac cgaatgattt attaacctca tcatactccc tattcggtcg
     3241 cataacaagg ttaataaatc atataatacg caagcaccgc atttggtacc caaatacatc
     3301 gcttgtcgag gtggcgttgc cccctacgaa ctcccccaat cacgcaacaa aaagtagcct
     3361 gttcggctat ttttattacg tgatttcgcc tcagaaaaag tagtctgttc gactattttt
     3421 ctactggctc atgcggtcaa acttgcacgc aagttgacct tatttttttg tctgcccgct
     3481 gttcgcaggc aaacaaaaaa gcaagccaaa aatcggcttg ctcgttcttc aaaaattgat
     3541 cgcatggact agctcgttcc gctattccaa gctgttcaat ttttggaaga actctagcaa
     3601 ctcaggataa aatgttttgt aatccaactt gtttccccag ttgtcttcca tccatttttc
     3661 gagttgcttt tgaaattgca ccgcttcggc tttcagctcg ctaggcaatt tttcggcaga
     3721 agtggccacc ggctttgcag ctgctggcgc aggtgcagat ccggcggacg acttcaatgc
     3781 ctttgacgca ttccgcatga aagtattgta ggcggaatag ctcttgaacc cttgtttttc
     3841 aaccatattt gtaccgattt tgactgaaag atcatgccga gcttcagcta attttttttc
     3901 caaatcttcg atatccattt ttgccatgcg taaactcact ccttagaatc tagttcgata
     3961 atttccgtta gaagaagatc aaattggttg atcgtttctt ctgaaagtcc accggtgtat
     4021 tcaataatag cgtcactatg cctttctaac agcttttcaa gctgttcaac gtcaatcgta
     4081 actgtcttag ccgtcatttt tttgttctcc tttttcgtca taactatgaa tcaaaaagcc
     4141 gtcacgttcg ccttttgcat agttcattag ttctttcata gcttgatcta gcgaagaatt
     4201 tttctttgcc atctttttac gcagtctttt tttcaactaa atcactcctc tattctttgc
     4261 tggtgtcatt gatcgtgatt tcatatccaa cgacttttcg cccacgcttt aaggttgtga
     4321 cgaaaaatga aactgacatc ttatcagata attcttcaat agcacgagta attacttttt
     4381 gaaaaaattg acctgcagga aggcgtttgt ctttaccaag aaaccaagat tcccattctt
     4441 ccaaatcacc tgtaatcgtt gtgtgttttt cttttcctct acggtaggat tcccagagtt
     4501 ttaacattat gagagcatat ttcccattga tccgagataa ttcacctaaa cgaaagctat
     4561 aaaacttttc tttgagatca agaacgtatg gagctgaatc agcagaaaat ttgaatctta
     4621 ctaacccgtc agcataaaaa tcaatccaag aaaataattg cgtcattctg agaccttgag
     4681 taccatcggg gcgctcgaca cgaagataaa gcgcagtatt ttcattaagc tttttgaaag
     4741 cttcagctat tcgacggtaa gaatctccag aggtgttcaa cccaaaatgt ttgataattt
     4801 ctaatgcggt tacctcgtat tcgtcatcta gttttgaatc tttagttaca aagctaaaac
     4861 agtagtctaa aactcgttgc tcaaacgatt taagccctcc aaatgcctta gctaagtcgt
     4921 ttccttgcac tactaaataa tcttgacggc ttagtaagtc ttttaatgca atatcagctt
     4981 ttttatttgg ttgtcccaaa ctgaaaatcc tccttttgta ctttttttaa aataatacca
     5041 tttattcagt ttttttgcaa tatttgaatt ttcaacgtgg aaaatagtat ttttgacgtg
     5101 gaaaatagta tttttgacgt ggaaaatagt attttcaacg tggaaaatag tatttatagg
     5161 cgctacaaac gctggtataa agccattcct tttcccctaa agtattttaa agtatttaaa
     5221 agtaatctat aaagtattct ctttaagcgc gcgggtgaga aaaaatttta aattc
//
LOCUS       DAZAOD010000135         5239 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000135 DAZAOD010000000
VERSION     DAZAOD010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.137"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(74..289)
                     /locus_tag="ACHDPO_002685"
     CDS             complement(74..289)
                     /locus_tag="ACHDPO_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFN3370247.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            513..1313
                     /locus_tag="ACHDPO_002686"
     CDS             513..1313
                     /locus_tag="ACHDPO_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFN3370248.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            1332..3200
                     /locus_tag="ACHDPO_002687"
     CDS             1332..3200
                     /locus_tag="ACHDPO_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFN3370249.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            3193..3684
                     /locus_tag="ACHDPO_002688"
     CDS             3193..3684
                     /locus_tag="ACHDPO_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFN3370250.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            3672..4226
                     /locus_tag="ACHDPO_002689"
     CDS             3672..4226
                     /locus_tag="ACHDPO_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFN3370251.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            4244..5239
                     /locus_tag="ACHDPO_002690"
     CDS             4244..5239
                     /locus_tag="ACHDPO_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFN3370252.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         1841 a          831 c         1070 g         1497 t
ORIGIN      
        1 tttaaaatga aaaaaccttc ccaataaagg gaaggttcat gaagataata acttttttaa
       61 taattatagc tttctaatat ctttcatcaa cttttctagt aatcattggg aaaaatttca
      121 agcagtagat cgcacaaata cctacgacga tataaatgat cttcgcaaaa atagttgttg
      181 aaccaccagc aatcatagct actaaatcaa gttcgaacaa gcctaccaac agccagttca
      241 accctcccac aatcaataaa gttaatgcaa tagcatctaa agttttcatt agaattctcc
      301 tttcttaaat gataaaacaa ttatatatca aaaagagaaa cattgcttat ataacgctca
      361 ggaattttag caatctatgc aaaaagatga aaattttttt tgctcttcca ttagtacaca
      421 ttttttagct gaagctgtaa atttcatgtc ttaatttttt ttagtgagct tttatactgg
      481 atttgtaaga aaaaagaagg agaggatcac atatgtcgga ttggttggat attgcaggaa
      541 aagtagtaat tgtaactgga ggttcctcag gaattggaag aagtatcgtc gaaaatttgt
      601 tgaagcagaa tgcacaagta gcgaattttg atgtaactga atgccgtata cagcatgaaa
      661 acctactatc tttaaaagtc gatgtgtctt ctaaaacgga catagaagaa gggatatata
      721 aagtaatgaa acatttcaag acgatcgatg gtctagtcaa taatgcagga ataaatattc
      781 cttctcttct aatagataga aatcatccaa aaagcaagta tgaattatca gaacaagttt
      841 ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt gatgagccaa gcagttggaa
      901 gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct ttcttctgaa tcaggattgg
      961 aaggatcaga aggacagagc tgttatgctg ctacaaaagc agcgatgaac agttttactc
     1021 gttcttgggc aaaagagtta ggaaagagga atgttcgtgt ggtaggtgtt gcaccaggga
     1081 tactggaaga aaccggtttg agaacacaag aatatgaaga agctctttct tatacgagag
     1141 gtataagcgt cgaacagctg agaaacggtt acagtcgaac aagtacgatc cctctaggaa
     1201 ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta ttatctttca gaaagatcaa
     1261 gttatatcac tggagtcacg actaatattt caggaggtaa aacaagagga taaaggatag
     1321 gggggacgca cgtgacgcta gtaaacagat ggtaccaatt attgaaatta ctagtcactc
     1381 acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa aaccagtaat caaaccataa
     1441 aaaaagatat tggggagttg aatgaagaaa ttgccggtat tgcaaaaatc atccaaaaaa
     1501 acaaacattt tgaacttgaa atttatgatt ttgatttttt tgatgagatc atgcaaggaa
     1561 aattgaaaac agccagtgat ttcaattcgg catccaaaag aatcgcttat ttactaaata
     1621 ggctgatcga aacagaggat ttcttacgta tggatgattt gtctgaagaa gtcggtgtca
     1681 gcagaggaac agtggtcaag gatctaaaga cattaaaaga gatgatcaat gattttgatg
     1741 taaagattac aggcacacca aataaaggac taagaataat aggagatgag ctagaattac
     1801 gactactttt attttatttt gtttctccct acttttcaga gacgaaaaca gaacagtttc
     1861 tagaagaaaa acaagcaatc aaacattttc agaagaagac gaatgctagt aaacaagaaa
     1921 tcaccctttt aacgaaagtt atcggtattt ctttgaatag aatctctagt aactatctgt
     1981 tgaagaagcc catcaatcgt tacagtgggt gttttgaata tatccaagaa ttcaatgaac
     2041 tgatcaatca gttggaagaa atctatgaac taactttgag ccaatatgaa aaagatttta
     2101 tcagttttcc tttgaacatc atcaacacaa gtataacgat gataaggaaa gctaactctg
     2161 atttgcgctt atatttcgac cccatgatga tgcgtattcg acgattagat ctcattgatc
     2221 tggatgagtc cttcttatat caagagatga aacagcacct ctctttattg ataaatcggg
     2281 taatttttcg ttatcgattg actgatttat tttatggtga gatagaaaaa aagtatcctt
     2341 tttcttacca aatcgctagc gaatgcatac aagcattaga agctatcttg caacataaga
     2401 tctctaaagt agagatcagc tacctaacgt tgtatttgga gttagcattt cgatatcaaa
     2461 aagagcattt ttcctctaaa aaagtagcca ttgttcatac gacaggaaaa ggaacagcat
     2521 taatgatcca aagacaaatc aaaaggatat tggggaggga tatacaaata acacatgttt
     2581 cagaagaaca atatgaaaaa gtagatctaa acaaatattt cgctgttttt acaacgattc
     2641 cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt gactaatctt tttgatgact
     2701 cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg attagccggg tttcattcta
     2761 ctgttttttt ctatcaaata tggaaagaaa aaaagacgta tcaagaatat ttaaacaaat
     2821 tagtcgctcc tttgatcaga ggctattatg tggatgaaga atttgaaaaa aggatcttga
     2881 aaagagaata tcagcaaagc acatttgtta acaaagaatt tgcttttcct cacacaacca
     2941 accagctatc tcaacacatt gttttatcag tagggctaat aactgatcaa ggtttagcag
     3001 aaacaggagg aaatggagtt atttttttat ttgccatacc tgaagaaatg acggctgaag
     3061 ttgagaatga attatttgag ctatacgata tcctatttga actcataaaa atgggaatag
     3121 atgagtttat tgaattagca ccgacacaag aatcattttt aaaactaatc aaaagtaaag
     3181 gagagagact tcatgaatga tatgtatcta ttcatagttt tcgcagcttc agcttatgtg
     3241 ctgcaagcag ttatcagttg gaagcaacta aagcatttca atcaaacata tagcgaactg
     3301 cgaagaaaag gaaaagtagc gattggtaaa cgacctggga aaatccgttc aggcacgatt
     3361 gttatgctag ctatagacga tcatgatcaa gttttagaag tcagaaaaat gcaaggggtt
     3421 acatctttgg caaaatttca ttcattacct gtctatgcgg gtgaagatat ccattacatc
     3481 gatcgttacc atccctcagt tcgagcggaa gatcgtttga cacaagcagc tttagaaaat
     3541 gccagagaag tatacttacg aatagaggca ggaaatgaaa aaagtgaaca accttcattg
     3601 ccttttattg ctatgctcaa taattttcgg atatggaaaa gtacgatcaa agaaaaaagg
     3661 agtgacaaac gatggatatc ataacaaaat ttgctgaggg atttatgagg ctgttccaaa
     3721 caggtgcaga aacattcata agctggatga caggaatcgt accagttgtc ttgatgctga
     3781 tggttgcaat gaatacgctg attgcttttt taggtgaaga ccgagtaacg aaagtagcca
     3841 aattatcagc gaaaaatccg cttactcgtt accttgtgtt accgttctta tctgctttta
     3901 tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct tccagaatac tacaaaccaa
     3961 gctattatgc tgctcaagct caattttgtc atacgagcaa tggtgtattc ccccatatta
     4021 atcctggaga attgtttgta tggatgggga ttgctcaagg gatcgaaacc ttagggctaa
     4081 attcgatgga gctggctatc cgatacttgc ttgtgggact gctgatgaac tttattggtg
     4141 gttggataac tgattttact actggatttg tatgcagaca gcaaggaatc gttcttagca
     4201 aaaaagtaga gctttcagtt gattagagaa aggagagttt taaatgtatg gtgatattaa
     4261 gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt attaggccga caaaagataa
     4321 acacaagttc atctatgtca caggtggagg tgagaggcca atgatcgtag ataaaataga
     4381 agaactgaca ggtatggagt ctatcaatgg gttcaaaaca tcaatacctg atagtgaaat
     4441 cgcgcttgca atcgttgact gtggagggac tcttagatgt ggaatttatc ctaaaaaagg
     4501 gataccaacc atcaatatcg tttccacagg aaaaagtggc ccattagcac aatatatcac
     4561 tgaagatatt tatgtttcag cagtagggtt agaacaaata cagccactaa tggaaactga
     4621 tgataacaaa gaaacagtaa atactgcatc tccagataaa aagtacaaat atgatacttc
     4681 taaaaagata accgagcaaa aagcagagca gcaaaactgg atagcaaaaa ttggaatggg
     4741 cgcgggaaaa gtagttgcta cattcaatca atcagcaaga gaagcagtag atacgatgat
     4801 ccggacagtg atccctttta tggctttcgt ttcccttttg attggtgtga tacaaggttc
     4861 tgggatcggt aatgtatttg ctaacattat ggcaccttta gcaggaaatg cagttggatt
     4921 aacaatcatt ggctttattt gttcactgcc atttttatct cctttgcttg gtccaggggc
     4981 agttattagc caagtgattg gaacattgat cggtgtagag attgggaaag gaaatattcc
     5041 tccccaatta gcattaccgg cactatttgc tatcaatact caaaatgcat gtgattttat
     5101 tccagtcggt ctaggtttgg aagaagcaaa agctgagaca gtagaagtag gtgtaccatc
     5161 agttctttat tcaagatttc ttaacggcat cccacgagtt atcattgctt gggtagcaag
     5221 ttttggatta tatagctga
//
LOCUS       DAZAOD010000136         5181 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000136 DAZAOD010000000
VERSION     DAZAOD010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.138"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..679
                     /locus_tag="ACHDPO_002691"
     CDS             <1..679
                     /locus_tag="ACHDPO_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFN3370253.1"
                     /translation="DVTELAKKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYI
                     GQVMNSMIPDNSTIYVGAGTTILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLT
                     GGEFSPITEEFIGEVAERSFESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAA
                     KIKCIVADYSKLNKSDVYTFRKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTD
                     NHDEPIH"
     gene            645..1598
                     /locus_tag="ACHDPO_002692"
     CDS             645..1598
                     /locus_tag="ACHDPO_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HFN3370254.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(1996..2970)
                     /locus_tag="ACHDPO_002693"
     CDS             complement(1996..2970)
                     /locus_tag="ACHDPO_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFN3370255.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3085..3519
                     /locus_tag="ACHDPO_002694"
     CDS             3085..3519
                     /locus_tag="ACHDPO_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFN3370256.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(3644..4666)
                     /locus_tag="ACHDPO_002695"
     CDS             complement(3644..4666)
                     /locus_tag="ACHDPO_002695"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HFN3370257.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5058..>5181
                     /locus_tag="ACHDPO_002696"
     CDS             5058..>5181
                     /locus_tag="ACHDPO_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HFN3370258.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETH"
BASE COUNT         1618 a          996 c          927 g         1640 t
ORIGIN      
        1 agatgtcact gaattagcaa aaaaaaataa agtaaaaaag ctatatggtg gcgttgaacg
       61 aaaggaacct tataatcgag aactatcgac tcaagaaaag attgatacga atgtagccga
      121 aaaaaaatat attggtcaag tcatgaacag tatgattccc gataattcta ctatttatgt
      181 cggtgctgga acaacgatcc tatatgcact tcctttcatt caaaagaaaa atctatttgt
      241 aattacaaac agtttgattg ctttcaacta tttaaagaat catacaagtt atcggatttt
      301 acttactggt ggcgaatttt ctcctattac agaagagttc attggggaag ttgcagaaag
      361 atcttttgaa agtttgaatg tcgatatctc tttcgctgca acaaacggca tatttgataa
      421 caatgtgaca accgctcaat ttattgaggg aaatattcag aacgcagcgc tcaatgcagc
      481 aaaaatcaaa tgcattgttg cagattattc aaaattaaat aaatcagacg tctatacttt
      541 tagaaaatta accgattttg attatctaat aaccgataat catttatcag aacaggattt
      601 caatcattat tcaaaatact taacaatatt aaaggagccc aaaaatgata ctgacaatca
      661 cgatgaaccc atccattgat tccatttatt ttacaaaaca ctttgaatta ggtacgatga
      721 cacgctttga ttctccggta cgctatgtag gcggcaaggg aatcaattgc ggacgagctt
      781 ctgctctact aggttcatca gttattttaa cagggttttt gggcggttat tttggcagta
      841 tgattcaaga tatgctgaaa aatgaaaatt tgtttgattt gcatttttta cctattgcag
      901 aagaatcaag aggtgccgtc acgatcatgc atgatgatga aacgcagaca gagctagtgg
      961 aagctggtcc tgaaatagca gatactacta tcaaaaaatt aatgaatgat atcaaactaa
     1021 tcagtaaaaa taattacctt tcagtcatta caataaatgg ttctgttaac aatccagatc
     1081 cctttttgta tgctaaatta ttacaatata tcaaagaaca aatagatcct tccacctata
     1141 tattaatgga tatatctgga caacatctcc gtgaagtctt agcaagtaag tataaaccga
     1201 tgttcatcaa acctaatatc catgagtttt cagatatcat ccatcaaaaa attactcaaa
     1261 aaagcgacat aaaacaccat ctaaaaacaa atccactatt taaagatatc gatgttatca
     1321 tgatttcttg cggctcgtat ggtgcagtag tcaaagtaaa agaagaattt tggaatgttg
     1381 agatccctaa gattcctatc attaatacaa caggctctgg ggatgccact gttggaggtt
     1441 ttgctcattc attagaacag aattatcctt taaaagaatg tgtaaggtac gcaatggctt
     1501 gcggcatgtc gaatgcacag caatcagaag tcgggaaagt tattccagct gatgtaaaaa
     1561 atttagcaaa aagcattaaa atcacagaaa tgaaataaat agtacaaagt aaataattgt
     1621 ttatatgaaa tgagacacaa agagactgtg acaaaaaacg tgtgtaccga cccccaaaag
     1681 ttagattttt tggtctaact tttgggagtc gatacattgt cacagtcctt ttttcgaata
     1741 aacggtgttc tcctgccaac tcctcggtca caagtcacaa tattcaacaa acatgagaag
     1801 ctattttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac gacctcttgg
     1861 tataaacggt gttcaaaagc ttgcatctac gctaatgagt ccaaccaagt caaaaatgag
     1921 gagctttttt ggctgtcctt attacttgat gcagggcagt tttttcataa tctcttttag
     1981 attaaatcct tttggttaca caaggttctc ttcaaagaat gttgccattt tttcaaatgg
     2041 aatgatgtct gtctggtcgt atagatctgt atgggatgct cctggaatga tcatgagttc
     2101 cttgttgtca ccttttagtt ctttgaaagc gtcctcccca aagtaacgtg aatgagcttt
     2161 ttccccgtga atgactaaga ctgcatgacg gatttctgga atataatgca atagttttgc
     2221 attcataagt gacaaccctg atgtcctatt ccaaccatca ttggagttta aagaacggac
     2281 atgatatccg cggtctgttt tataatacgc atgatagtct ttgacaaatt gaggagcatc
     2341 ttcaggcaac ggatcaacca cacctccagc acgtgcgtag tccccttgtt tgaaatcaat
     2401 gatgcgttgt gcatttaatt cttcacgcat ttcatatcgg gcattttcat ccataacatc
     2461 gaagtagcca tttgctgtta ctcgagtcat gtcatacatt gtggaaacaa ctgttgcttt
     2521 gacccgcgta tcgatagctg ctgcattcaa tgccatacct ccccatccac aaataccaat
     2581 gattccgatt ctctcagggt ttacattttt ttgtacagat aaaaagtcta ctgccgcttg
     2641 gaaatcttcc gtattgatat caggcgaagc aacatatcga ggtactcctc cgctttctcc
     2701 tgtaaacgat ggatcaaacg caatcgttaa aaagcctctt tcagccatcg tctgcgcata
     2761 tagaccagac gattgttcct tcactgcacc aaatggcccg ctcacagcga ttgccggcaa
     2821 tttcttttca cttacttctt ttggttcata taaatcagcg actaatgtga taccaaaacg
     2881 attcgggaag ctcacctttc gatgattgac ttgattgctt tttggaaata ctttgtccca
     2941 ttcttgtgtg atgtttaatt ctttattcat attctagact ctcctttgat caaaattgac
     3001 atttgttttt gaatgtatta ttatgataaa acttaaactt gactttaggt caaggtaaaa
     3061 attttatttt aggaggattt ttttatgtat tccattggac aagtgtctga aatgtttgga
     3121 ttgcctgttt ctactttacg ttattacgac aaagagggat tatttcctga tatccagcgt
     3181 gtttctggta ttagaaaatt ttcagagaat gagttagagg ctttaagagt cattgactgt
     3241 ttgaaaaaat ctggtttaga aataaaagac attaagcaat tcatggaatg gagcaaagaa
     3301 ggcagtaaga catttgaggt tcgtaaagaa ctatttgaaa aacaaaaaga agtagtagaa
     3361 aaagaaatag caaaattaga aagagtactc gctatgctaa actacaaaag ctggtactat
     3421 gaagaagcaa taaaagccgg caatgaagaa gccgtattga caatgattcc tgatgattta
     3481 ccccaacatg taaaagaagc ttatgtacat tctcattgaa caaacggata actcactctc
     3541 cttctctatg aacttcatga aaacatgaat aaacacctct aactgattgt tagaagtgtt
     3601 tattttttca ctcaagtatc ctgcacttac aaaaatatcc tttttaccgc catcctaatt
     3661 ctggagcgat atcttttacg attgtttcaa gcaagtgcat gttatattct acccccaaag
     3721 tattaggaat cgtgacaagt actgtgtctg cttctttgat tgcttcatct tcagctagct
     3781 ccttgattaa ttgatcaggt tcaccagcaa aagtttttcc aaaaatcgtt gggtttcggt
     3841 gataagcaag atagccgaca gcatcttgtt gcggactacc gtcttgtcca aataagcgtc
     3901 gatccaaatc agtggtgatt ggctgaatcg agcgagtaac taatgttctt ggttcaaaat
     3961 catgacctgc ttgcttccac gcttctttat acgcacgtaa ttggtttgct tgttggatat
     4021 ggaatggctc gtgggattcg taattgacta atgtagatga ttgcagattc attccatgtt
     4081 gtgctgccca gattgccgtt tgctgcgaac cagctcccca ccagattctt tgtcgtaatc
     4141 cttctgaata aggttctatc cgtaattttc ctgatccttg tgggaacatt ggttgaggat
     4201 ttggttcttc aaatggtttt ccttcaagta attccaagaa ttcaagggtg cgttcccgtg
     4261 ttacctcttt gatttcttct tcactgtaat cataaccaaa gtatttccag ccatctagaa
     4321 cttgttcagg tgaaccacgc cccactccta gttgcactct tccttgcgtg atgatatctg
     4381 tcaatccggc attttctgcc atataataag ggttttcata tcgcatatca ataagtcctg
     4441 taccgatttc aatcttactt gtctttgcgc cgattgccgc tagcaaagga aacggcgacc
     4501 caatctgagg ggcaaaatga tgtacgcgga aaaacgctcc gtccactccg attttttctg
     4561 cttccaccgc taaatcaatc gattgcaaat aagcatcttg agctgatttc acaagcgatc
     4621 cttgctccat ccaatgtcca aagcttaaaa agccgatttt tttcaaggta atgacctcct
     4681 ttaaacctac aaaaatggaa ggttttttat ttttaatatg aactgattct actacttttt
     4741 ttcttaaaag acgaataatt gttctcgcct cacaatcaag aaatgtatcg gcttactaca
     4801 cccctacttt cttcatcatc tgccgtgtct taatctcttt taacagtctg ttacatcgtt
     4861 gatttttgac tcaaaatgat tgtttctaac atgtatttat ggtaaaaaag acaagattag
     4921 ttctttgtac acatcgattt atacgctgaa caaaaagaaa tatataaact aagaaaccca
     4981 ttgttttttc gctccatcac atagagttta ctttagataa acagtgacat ttactaatcc
     5041 ataacggagg aaatcaaatg aaaaaaatct atttcttatg tacgggcaat tcatgccgca
     5101 gtcaaatagc agaaggctac gcgcgtaaat acttgtctcc ttcaatgttt gagataagaa
     5161 gtgcggggat cgagacacat g
//
LOCUS       DAZAOD010000137         5133 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000137 DAZAOD010000000
VERSION     DAZAOD010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.139"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1765)
                     /locus_tag="ACHDPO_002697"
     CDS             complement(<1..1765)
                     /locus_tag="ACHDPO_002697"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3370259.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1725..3479)
                     /locus_tag="ACHDPO_002698"
     CDS             complement(1725..3479)
                     /locus_tag="ACHDPO_002698"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3370260.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3589..4158)
                     /locus_tag="ACHDPO_002699"
     CDS             complement(3589..4158)
                     /locus_tag="ACHDPO_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFN3370261.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4176..>5133)
                     /locus_tag="ACHDPO_002700"
     CDS             complement(4176..>5133)
                     /locus_tag="ACHDPO_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFN3370262.1"
                     /translation="CSLSLNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIA
                     EHRFYYLKELIDQVLFVKNRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSA
                     DVLKVEEITYENILKDINFDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIEN
                     KKNLSSPFLVMQEMDYQFFTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFD
                     LSGGEKQRLLVSIASLSKTNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHD
                     PEFLYKTCNRIIYLKNGGIKKDIKLRVEDSTLIEQIFNDITK"
BASE COUNT         1710 a          964 c          695 g         1764 t
ORIGIN      
        1 atcgtgattg agcttctttt tcatagacga atttctcaga tagtttagtt ttctttatga
       61 gatttttgta tatttctgac cttcgataca actcattatg agtaccttga tcaactagtt
      121 ttccttgatc catcactaca attttattta ccttttcaat agacttcaag cgatgcgata
      181 taattagtac tgtcttatct tgtattaaac gatttaaact ttcctgaata cgtttttcat
      241 tttccgcatc taaactggca gtaatttcat ctaaaattaa aattggcgca tttttcaaaa
      301 aagcccgtgc tatggatagg cgttgtcgct ctcctccaga aagtgaactt ccgttttctc
      361 cgaccaatgt atgataaccg tcaggtagtt tttcaataaa gtcttcgcag ttagctaaac
      421 gagctgcttt tttcacttcc tcatctgacg cttgactatt tccaatacgt atattttcca
      481 aaatacttgt attaaacaaa gttacctctt gaaaaacaat agcgattttg ctaaacaaag
      541 aagctggaga tacacgttta atatcatacc catcaattaa aatacagcct tcatcataat
      601 catacagtct agacactaat ttcaagatac tagttttccc ggaaccacta gcacctacta
      661 acgcagtcac ttctccttgt ttagccgtaa aagagatatg atctaaaatt ggggtattgt
      721 tatcatatga gaaagagaca tctcgcaact caatgtcaaa agatttcaga ggactatctg
      781 atccctcttg gatactggtt tccttcatag ctctaattcg ctgtatttta ggagctaaat
      841 aaaatatttc aagcactgct tctttcatag aatcgaagga atcctttatt tttattgcgg
      901 ctagtaagta accaacgacg tagagtatag tcacttcacc cgttaacagt aagtgaacac
      961 ctactagaat gactactgct aaactaacat atgagaaaat agaggataag gccatgactg
     1021 aaaaagtact taattctacc tttaaatgaa tcctttcact ctcttccatt tttttgaaaa
     1081 gtctgtcttg aactttttta gatagattaa agctattaat ctcttgctgc aattctatag
     1141 tttcttgaaa ttcttccgag ttctctctca aagtatcgta atatttagta ttggctttcg
     1201 tttgggattt ctttgataac aagattaaga caaaactaaa taacgttggc aaaataacag
     1261 ctaatcccat tttgacatta ccaaccaaaa gcatcactga aataaaaggg aaaaacagag
     1321 ccataccgcc ggctttaggt attgcatgac tcatcgcatg ctcaatacct tcaacgtcag
     1381 acatgatagt ttgagataaa tctgataaat tatgttttga aaaataggat aatggtaaat
     1441 ttgacaaatc gtctgcaatt tgcactctta aatgcgcact ttctttataa gtactattat
     1501 ataagttttc atactcccta tctaacaacc aatacatgaa aagcaaagta acaaacgata
     1561 cggcaaaata aagccaacgg ggctttgtat tttctaaaac taattcgtct atcagcatca
     1621 ttataatgaa tgctggtacc atattaatgc agtatacaaa aaaactagaa atagaagctt
     1681 tagttaaagc ttctgcgccc tgatcactta aagcaaattt gtttttataa aaacttttca
     1741 ttgtcaagcc tccaatcatt tgcattctca taattagtga ccaattgttt atacacttga
     1801 tgtttagcca ttaattcatt atgatttcca cgttctacta ttttcccttc tgacaagaca
     1861 agaatttcat ctacagattt aatgctggat aatcgatgag ctatcataat aactgttttt
     1921 tctttcatca gatgttgaaa agccttttgt agttcatact cattatctgg atcaatagat
     1981 gcactggctt catccataat aacaatcttt gcatctttta aaattgctct ggcaatagct
     2041 atacgttgtt tttctcctcc tgacagataa actcctttac taccaattaa ggtatgctct
     2101 ctttcgggaa atttttctaa aatcgattcg caaccggcta atcttagcgc gtcaaatact
     2161 ttacttgctg gcgcttgagg atttgctata gaaacgttat cgtaaatact ctgattgaat
     2221 agtttcgtat cttgaaagac aaaagcaatt gtgttaataa ttgtgtcttt tgaatagtga
     2281 tttaaaggct taccaccaat tttaatctgt cccttatcca cattgtagaa acctgaaatt
     2341 agtttagcta tcgtactctt tccgcttcct gattttccta ctaatgcata aattcttttt
     2401 tgttctaaaa ctaagttgaa attttctaaa acacactctt ctttgtatga aaagctgaca
     2461 ttttcaaatg caatgtcaca atttttaatc tgtgtctcgt tcccatattt tagttggtct
     2521 tgcttcattt ctaaataaag ggagtctagt gtttcgactg catatcttgc ttcaaacaag
     2581 tgcatactta catacattat tctcatgaaa gaaacaaaaa taattccact taaaaaaaac
     2641 aacatcaaca agtcaacagc taatatcttg ggagtggtaa gagaagttat aaaaaaggtt
     2701 ataggaacta tcaaaatgca aactatgcca aaaaatagcc attgaaaaag aacaaaaggt
     2761 gttttcccac tcaaagaata cttatatgca aacttagcat aatcgttaat tgctttattc
     2821 aaggctttaa atgatgttac tttagcacca aatatcttta taacttgaat tccgcggata
     2881 tattctaccg tttcagagct taacacatct aacgattctt gatatttttg aataaaattt
     2941 gtattctctg tcattttctt taacaagaat acaccaatta ctaacatggc gattagaacc
     3001 aatccaattt taaagttaat gaaaaagcct aaggcaactg ataaaacagg tgttactatg
     3061 gcttgagcac tatctggaat caagtgagca attgccatat gtgttttagc cgcgttgtca
     3121 tcaattgtct ttcgaatata tcccgaagaa tttaaatcaa aaaaacgaaa acttgcttct
     3181 gttaaaccgc taattccctt ttttctcaaa ttagtctcta agcgaaaccc aaggatatga
     3241 gaaaataagc cagaaaaaat ataaaataaa gctcctaaag ttaaccaagc aacagtttga
     3301 accgcataac tcttagctaa atattcatct cctacaataa ttagagactg aagaaatttg
     3361 taaatactgt aatatccata gactgttaat acgacagaaa aatcagaaaa taaagtggct
     3421 aaccatccgt agtatttcat tttagggaca taactaaata attttttgta tactttcatt
     3481 ttttcctccc ccgcattcaa tttcttctct tattcgttta caactgttaa tgctttccgt
     3541 aatagcgtaa attagagatg tacaaacaga taaaaggtaa actacgttct attttttgta
     3601 tttttttaag acttttcttc caatcaatac accaatcata gataaacttg ctacaactaa
     3661 cactgaaatg attccccata tacctaccgc atagtggatc attgcatcca ttgttgcagc
     3721 agattgtcct ttatctatcc aatcttgacg aaaacgatct gtaaagaacc atataggaat
     3781 ccactgtccg gcagcactgc ctaattgcat tagagcccaa gacgcaactt gaggaattgc
     3841 tcgatcatat ccaaatacag atagaataat atcagctaag atcgccatac taatcgaact
     3901 gataaaccaa ggtaagtacg ccccgcccat taacgtaaaa aataacaata aaacaattgt
     3961 gtaaatagta aaaattcctt ttctagggta gttatagcta atataaacaa atatgattcc
     4021 agataataat ccaaaaatcc cgggggatat gctgtgacca aacgccccac caatactact
     4081 aaccattatt gaaaaaaagt aaattactag ggaaataact gtagctaaac caataaaaat
     4141 ataatctttt gttttcatat atattctcct caattctatt tcgttatgtc attaaaaatc
     4201 tgttctatca aagttgaatc ttctactcta agttttatat ctttttttat tccaccattt
     4261 tttaaataaa taattctatt gcatgtttta taaagaaatt ccggatcatg agtagctata
     4321 actactgcac ccttttcttt taagtcttta ataaggtcag caatcctttc catattaata
     4381 taatccaacc cacttgtagg ttcatcaaat agaaataaat tagtttttga caatgaagct
     4441 atagaaacca ataatctttg tttttctcca ccggataaat caaacggtaa ttgatctttc
     4501 attttataaa gttccatttt ttttaaaatt ttttcttgct gatctttact aactatttca
     4561 ttccccaggg ctaactcgct cctcactgat tctgtgaaaa attggtaatc catttcttgc
     4621 attactaaaa acggcgatga caaatttttt ttattttcga ttatctttcc tttggtaggg
     4681 cgaataatct tcatgagtat tcttagtaag gttgttttcc ccacaccgtt tttccctacc
     4741 aaaccaataa catctccaac tttgacatca aaatttatgt cttttagaat attttcataa
     4801 gtaatttctt caacttttaa tacatctgca cttacctttt cgatataggg aacttcaatc
     4861 gaactattaa aaatgtcaaa tttccttaat gcgttattgt tttcagtttt taacaactga
     4921 atagttgtag tttttacagt tctattttta acaaatagaa cttgatcaat taattctttc
     4981 aaatagtaaa aacgatgttc agctataaca atagtaaatc ctttattttt taaatcacaa
     5041 agtaagtcag caagtttctt agtcgctttg aagtccaaat ttgaagacgg ttcatccaat
     5101 ataattaatt tagagtttag cgataaacta cat
//
LOCUS       DAZAOD010000138         4961 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000138 DAZAOD010000000
VERSION     DAZAOD010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.140"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(139..1338)
                     /locus_tag="ACHDPO_002701"
     CDS             complement(139..1338)
                     /locus_tag="ACHDPO_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFN3370263.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1468..2844)
                     /locus_tag="ACHDPO_002702"
     CDS             complement(1468..2844)
                     /locus_tag="ACHDPO_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3370264.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2844..3500)
                     /locus_tag="ACHDPO_002703"
     CDS             complement(2844..3500)
                     /locus_tag="ACHDPO_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3370265.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3510..4787)
                     /locus_tag="ACHDPO_002704"
     CDS             complement(3510..4787)
                     /locus_tag="ACHDPO_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFN3370266.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4806..>4961)
                     /locus_tag="ACHDPO_002705"
     CDS             complement(4806..>4961)
                     /locus_tag="ACHDPO_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFN3370267.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
BASE COUNT         1556 a          903 c          608 g         1894 t
ORIGIN      
        1 tcggagtaag tggcttcgac gattggataa ataaattcaa aatcaagcgc ggcatcaatc
       61 tttcgaacga gatgatcttg aggaactaga tcatcaatcg taagcatcgc aaattgattt
      121 ctaccattcg tattgttttt agacatcata gctatcactc cttgcattcg ttttcataaa
      181 tctattataa aagaaaagac tgtagacatc atccataaaa tggactttgt ctacagtctg
      241 cgcattctca ttagagaaca ctcccttttt tgtgactttt ctgaagctag agtgaatact
      301 ttcaactgca ttagtagtgt acatgatttt tctaatggcg ctgccataat caaagagttg
      361 ttcaacatga gaaaagtttc gtttgcatac atctactgca ccagaataat gagaccaccg
      421 attttgaaaa ctgtcgaagg cagcgtgtgc agcgtttaaa gaagaagcac tgtagaattt
      481 tttcatgtct cgacagactt ccttataatc cttacttggg aggtatcgta acgcatttcg
      541 aacaagatga acaatacagc gctgcacaat gacagaagga aaaattgctt ttgcgccttc
      601 tttgagaccg gaaacaccgt ccatcgaaat gaaaaaaaca tcttctacac cacgtacttt
      661 cagttcatca aatacttgca tccagcgatt tttagattct gtttgattga gccataggcc
      721 taaaatctcc ttgtttcctt taagatcata gccaagaatg gtgtacacag catattcttt
      781 agcttcatag ttttcgcgta aagtgacgta catacaatca acgaatagaa atgcataaca
      841 cttggctaat ggccgagctt gccattcttc caattcagga aggacggcat ccgtgatatc
      901 agaaatcatt tcgtgggaaa tatcaaagcc gtaaatatct tcaacggttg cggcgatatc
      961 gcattgactc attcctcgtg catacatgga aagaacctta ccttcgatgt cggagacatc
     1021 tcgttttcta ttaggaatca actcaggttc aaaagaagcc tcccggtctc tgggaacatc
     1081 aatgtttact ttaccaaagc tcgttttaag cgtcttattg ccataaccgt ttcgtcgatt
     1141 gtcatgtttc tttggctctt tagaatgggc gtcataccct aaatggttat tcaattctcc
     1201 ttgaagcatt ttttcaaata agggaccaaa cacatctttt aaaacatctt gcatatcctc
     1261 tacagattcg ggttgataag tattcaaaat ggattcagct aacttctcag catcaggatt
     1321 tcttttcttt ctagccatcg tgtaatcacc tcttgatctt attttagaaa aataaaaacc
     1381 gtgaagcaac cacccgccta ggattgatgg ttacttacac ggtttatatt acactctcat
     1441 ttttggtgct aaaaagcacc gaaaatttta attattgtca attaataatt cttttggatt
     1501 ccttcttaat atattgaatg aagaaataat caatgataca agaagtacta aactcataaa
     1561 tataactaca taaatcatga atttaggtaa tacattgata tctaaacttg ataatgtctt
     1621 gttaaatcct tcagcttctg ccccaccacc taattggcta gatgcagatt gtttagctat
     1681 ttgtttagct atatcaccag taaccttatt caatatatta ttcccaagct tgtcagctgt
     1741 atattgagct aagaaatagg aaccaacgaa tgcggggatt gatataaata ccatctcaat
     1801 taggaattga ccaaaaattt ctaattttga tatacctaat gatagtaata ctgctatttc
     1861 tttctttcta gcattcatcc ataagaataa taataatgaa actacaactc ctgcaaatat
     1921 taatgagcca aaaaataatt tatttgaaat tgagtaaata cctgatatag attgttgtaa
     1981 tgcagggtaa tttgatgaac ttttaatcaa attatattct ctccaattta tatctaattt
     2041 cccaagatct tttattacac tatcaagatt cttatcacct tttacaaaga atgttgcatc
     2101 ttggtataca gctgtatctt cggtattacc ataaacttta gcagctgtat gaatatcagt
     2161 gattaatgta ttttcgtata gttcttgtgc tgcacttact ccaccgctat tatgcccatc
     2221 gaatagacct ttaatttcta cttctactgt ttcatctgca cctttctcat tatcagcatc
     2281 aaataaatta gattttattt ttatcttatc tccaacttta aggttatttt tttcagctaa
     2341 atctttatgc attaagattt tatttttatc ttcattttct aaatgctttc cttctactaa
     2401 tttatatgct tctgatacaa attttgtttc ttttgttgag tcgttaaccc cagttaacat
     2461 aactgttctt ttaaaattct ttgctctttc aggtgattga ttcgcaagag tctcttgagt
     2521 ttcaataata tcataatcaa ctaaatctgc aacactgttt attcttttta cataggagtc
     2581 tatactatct gtttgagata tctttttaat atcttcacct tttacatttc ccccacctct
     2641 aggtgttcct ggatttactt gtctatttat ctccatagaa aaactatttg ttatattagc
     2701 aaatgtttct tttgaagctc tgtccgtagc atctttaata gataaactaa tgagacttaa
     2761 agttgacata gataaaataa ctaatatgat aattaatgat tttaaacttt ttctagttac
     2821 ataagcaaat gcatttttta tcattattca acctccaaat tcattttatt tacttttttc
     2881 aactttttac cacttagttc taaaatgata tccgcagaat ctgctacttc cttactatgt
     2941 gttacaacta ttacacattt atttctatct ttagctaatg tctttaatat attaattatt
     3001 tctccagcag taacactgtc tagattacca gtaggctcat cagctagtat tattggagca
     3061 tctgatacca atgctctagc aatagctact ctttgttgct gtccaccaga taatttcata
     3121 acatttcttt ttatttgttt tttatctaaa cctagttcaa acaagatact ttcatctgct
     3181 gatttattta ctaatctaat attttcaatt ggtgataaat aatctattaa attatagttt
     3241 tgaaatacta aagatatatt attttttcta tgattactat atcctttatt ttgtatatct
     3301 tcattcttaa acaatatttt tcctgtttga ggtttatcaa gtccagcaag taaggaaaga
     3361 agtgtagatt ttcctgttcc tgactttcct actatcgcat aaaacttccc aagttcaaat
     3421 ttttgattta ctcctgacaa aactttttct ttagaatttg cataactata tgctacattc
     3481 tttatttcta atatatccat tattttctcc taacttattt ttgataagat ttctttaggc
     3541 ttcttgatta acattaatga agaagcaaat acaactgata aaacaataat acttattaat
     3601 attaaataac tttgtccaag tgttgttata tttgacataa aactactatt atttattaaa
     3661 cttccaccgg aaatcattga atcctctgag ttaatgaatc catctacaat tacttttagt
     3721 aatacatttc ctaaaaataa ggaagatatt atacttggta tcgatatgaa tattaactcg
     3781 aatataaatt gcattataat ttgtatctta gatgttccaa tagataagaa tatacctatt
     3841 tcataaattc tttcccttaa ccatagaatc aagattaatg aaagaacaac catcccacct
     3901 aacataatag aataagtcat tacttttatt atatatttta ttccactcac tgactctaaa
     3961 gactcttcaa acgcattaga atctttttca acaaaatact ttgactcatc aattttaagc
     4021 tctttcaatt tgtttaaggc taagtctgta gattctgcac taccagaata cattaaaatt
     4081 ttatttgcaa tttcattatt ttctgaatta tttaatatct cttggcttgt tgaataatct
     4141 acaaacacca tattttcact aaaatcagaa gataatcctg tatatgtttc ctgtttttta
     4201 ccagaaaaga tccctataat tttaaattta tgacttttta tttttccact tttttcaata
     4261 tctagtaatt caagatcaac ttcatcacct aattttagat tgttttgttt agcaaattct
     4321 tcatgaacaa taattgaatt cttatcattt tcttctatat ttttaccttc tttaattgta
     4381 aatactccac tactaaataa aatatttctt ttagtattat ttgtagcttc gagtgaaaca
     4441 acattcttaa attcgtcaga taaatcttct ctatttattc tttgttctcc gctaactact
     4501 ttagcatctt ttagttttgc taatccatca tattgaatta ttttttcttc aatttctttt
     4561 aatttttcaa tatctttaaa ttgattaaca ttaaaatatt taccatcttt ttttgttatt
     4621 gatattgaag aattagaact ttcatataaa gccttttcta tttcattgct tgatttcatt
     4681 attgttaaac aagaatacaa gcaagaaaga actatagtta atatgataaa aattattaaa
     4741 gttctatttt tctttcttgt aatatatgct atagcatttt ttatcacttt cctaactact
     4801 cctctctatt ttcttactcc ataactaatt gcatccactg gacaagcatt tttacatcgt
     4861 ccacatctga tacactccag atgattgcaa ttctcaactg aatctttatt catttggcaa
     4921 acttttttac attttccaca attaatacac ttatccttat c
//
LOCUS       DAZAOD010000139         4957 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000139 DAZAOD010000000
VERSION     DAZAOD010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.141"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACHDPO_002706"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACHDPO_002706"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFN3370268.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="ACHDPO_002707"
     CDS             complement(1297..2133)
                     /locus_tag="ACHDPO_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370269.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="ACHDPO_002708"
     CDS             complement(2317..3534)
                     /locus_tag="ACHDPO_002708"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFN3370270.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3844)
                     /locus_tag="ACHDPO_002709"
     CDS             complement(3683..3844)
                     /locus_tag="ACHDPO_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370271.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3917..4000
                     /locus_tag="ACHDPO_002710"
     tRNA            3917..4000
                     /locus_tag="ACHDPO_002710"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4957)
                     /locus_tag="ACHDPO_002711"
                     /pseudo
     CDS             complement(4240..4957)
                     /locus_tag="ACHDPO_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1521 a         1024 c          796 g         1616 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaa
//
LOCUS       DAZAOD010000140         4933 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000140 DAZAOD010000000
VERSION     DAZAOD010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.142"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..972
                     /locus_tag="ACHDPO_002712"
     CDS             85..972
                     /locus_tag="ACHDPO_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFN3370272.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="ACHDPO_002713"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="ACHDPO_002713"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFN3370273.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="ACHDPO_002714"
     CDS             2274..2720
                     /locus_tag="ACHDPO_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFN3370274.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="ACHDPO_002715"
     CDS             2993..4345
                     /locus_tag="ACHDPO_002715"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFN3370275.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="ACHDPO_002716"
     CDS             4516..4803
                     /locus_tag="ACHDPO_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFN3370276.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1395 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt ttt
//
LOCUS       DAZAOD010000141         4738 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000141 DAZAOD010000000
VERSION     DAZAOD010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.143"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(80..1888)
                     /gene="pepF"
                     /locus_tag="ACHDPO_002717"
     CDS             complement(80..1888)
                     /gene="pepF"
                     /locus_tag="ACHDPO_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFN3370277.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2064..3062)
                     /locus_tag="ACHDPO_002718"
     CDS             complement(2064..3062)
                     /locus_tag="ACHDPO_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFN3370278.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3288..3941)
                     /locus_tag="ACHDPO_002719"
     CDS             complement(3288..3941)
                     /locus_tag="ACHDPO_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFN3370279.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4273..4671)
                     /gene="spxA"
                     /locus_tag="ACHDPO_002720"
     CDS             complement(4273..4671)
                     /gene="spxA"
                     /locus_tag="ACHDPO_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFN3370280.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1389 a          999 c          742 g         1608 t
ORIGIN      
        1 aaaaaatacg tcgactccct tacaagagag ccgacgtatt tttttcgttt ctattcgaga
       61 aaatcaaaaa tagaaagcct tataaacgat cgatcaattc ttctaattca tttagacgtt
      121 gttcaaacat cgacattgca tcttcaatat atgcagcctg tgtcatatca actcctgctt
      181 ttttcattac ttccacagga taatcgctgt tacctgcttt taggtaagcc aagtagttct
      241 ctagtgcctc tggttcctgg tttagtattt tcttcgccag tgctgaagca gcagaaaagc
      301 cagtcgagta ttggaaaaca tagtaattat aataaaaatg cggtatccgt gaccattcga
      361 atttaatttc tgggtcttct tcgactgctg gaccataata ttttgcattc aatttaccat
      421 aactatcact taggtattca ctagtcaatg gcacaccttt ttcatcttcc gtatgcatga
      481 aatgctcgaa ttcagcgaat tgtgtctggc ggaaaactgt tcctttaaac ccatccaagt
      541 aatggttgag tacataagcc cgtacacgag ggtctttttc tgtttccaat aaatactccg
      601 ttaggatatt ttcattcgtt gtcgaagcaa tttctgctaa aaagatggag tagtcgccgt
      661 acacataagg ctggttcgaa cgagtgaaat aactatgaac actatgtccc atttcgtgga
      721 caagcgtaaa tagctgatcc agcgtatcat gccaattcaa taaaatatat ggatttgtgt
      781 catagcttcc cgaagaataa gcaccgcttc gtttcccttt attttcgaca acatcgatcc
      841 aacgttcaga gaatgctttt tctacgatgg ccatgtattc ttcacccatt ggtttcagtg
      901 cttctaaagc tttttctttt gcttcttcgt acgtaaaggt aattggagct tcccctaaga
      961 ccggtgtata aagatcatac atgtgcagtt tttccacttc taataaacgt ttccgtaatt
     1021 ccatgtatcg atgtaacaaa ggcaaatgct tgtttaccac gtctaccaaa gtatcgtata
     1081 cactttcagg aatatgatta ttgctcaaag acgcttctct ggcagagctg taattacgga
     1141 ctttcgcttt aaaattatgt ccttttatat gtgtgcctaa agtagaagca aatgtatttc
     1201 taaattgttc gtaaacactg tacaacccct taaatgctgc ttcgcgcacc cttcgatccg
     1261 tgctttctag caactgacca tacacgccat gagataattg gactatttca ccattttctc
     1321 cttcaatcgt tggaaaaact agatctgcat tattcaaaac agcaaatgta tcacttgaag
     1381 catcaaagat ttcacctgct ccagcaagaa gagattcctg ctcagcagat aagacatggg
     1441 ctcgattatc tactatttgc tggatataat ggcgatagac ttccaatttt ggttcttctt
     1501 tgaaatattg ccaaatctgg tcatctgaca attgcaatat ttctggttca aaccaggaaa
     1561 cggcttcact aactttcgaa aacagactgc ttgctcttgc ataaagcgct tggtaatctg
     1621 tatttccagt gtcttgatcg tttttaaggt gcgcatatac ataaatgact tcagtttggc
     1681 gataaaccct caatacgaat tcaatcgcat ttaaaaattg agaagcgcct tgatcaagtg
     1741 ttcctttgtg tttttcagat tgttttaact cttctgataa ttccaaatat ttctcatcaa
     1801 actcttggtc gcttgaaaag atcttggtca agtcccaagt taaattttca ggcaattctt
     1861 ctcgttttgg caactgcttt acttccatga aatccactcc ttttcttccc ttagctctat
     1921 ctatcaaaat agatcatagt ctaacatcca catgtcacag catctaactt ttctactcat
     1981 tcatgtgtct gcttccatca attttagcat aactaaatct tgttttacat agaaaaccga
     2041 ttcctagcct atttttatac ttactatttt ttcaaagaag acaagtgtat gcattcgtta
     2101 aaaaactgct gatagaccat ctcttcatca atcataggaa aaagccattc ccttttatgt
     2161 tcttttattt ggcaaagcca tgagttgaaa tcaggaactt tctggttttc caaggcttct
     2221 tcgtacaaca ttcgataaag aaaaacctgt tcttgtaaat aaaagaaaaa ccgacttttt
     2281 tgatagatcc acgatgatag atgcaaaaga tgtttatgac gcaagtagca ttgttcttgt
     2341 atggatactg tattcttttg cttgtgaata agttggcgtg tcagccattt cttcccatct
     2401 tcactcactt tttctatttt tttcatttgg ttcattttaa tttcgttact agtgaatatt
     2461 tctttaaggt ccctactaga aaaagtccag cagctactgc aaaaggaaat atgccctgat
     2521 acagtctctg taatatgatg atacaaataa agcttttgtt tcttgagatc agctttccag
     2581 caatgcactc ctctttttct attatagtag cagcaacttt tttctatcaa tgagaattgc
     2641 gattgtccaa gaaaagaatt accaagtatc caccatactt ggtaactgtt attcaaataa
     2701 ttttgggttc tttcaataaa tctctggtga gacagtctag aacattggat ttctattgct
     2761 agattcgcca acaaaatatc cggcctttgc cgcaacctcg gcaaataggc ttccaaaaat
     2821 actggttcta ctgactgtcc cagccaatcc atgaagcatt cctttaactg taagtgctct
     2881 tttgattctc tttcactaaa gaccgaacag ttatctgatt tttgatgggc aaaatgagca
     2941 cattttttct ttcccttttt caaaatcact ctttttcgac agccacgaca ataatatttc
     3001 tttccttttt ctgcatgttt agcaaaacag cacttattat attcattcat tgcaagcagc
     3061 atttttctcc ctctgaactt atttacgtct aagaatttat ttacacgaaa aaagagggcg
     3121 tgaaaaagct attctgcatc aagtaataag aacagctaaa caaaaatagt tcccaatatt
     3181 tttcgtttgg ttgggcttgt taccgcagat gcaagctttt gaacacattt atacgaaaaa
     3241 aagactgcga cacaattttt gtcacagtct cttactataa tgctgattta tacaaaataa
     3301 aatttcgttc gctcgatagc attacgcgcc atcagacatt gtccatattc attcaatgtt
     3361 tctggtgtac gatcgctctt ttcagcaaac tccaaaattc gagcaatctg attctctaca
     3421 tccgcttggt tgagattttc catccagaag tgaacgacta ggtaatagcg ctcttcgaat
     3481 aaatacaaat cagtccaagc agactctagt tcgacatctg ttgcaagttg gatcacttgt
     3541 tcaaaatctt caaaagcaaa agttgcttgt ctttcctgtt cttctagggc gcttccagat
     3601 aattcttcct ccggatcgct gccaataatc tgctgacgaa gaaagtcact cacatcttct
     3661 gaatcaacag tagaatcttc tgattgagaa atttcttcat ccggaagatt tttactgata
     3721 aacagttcta atccgtctcc ttttggcaaa acttggaaag tgacagcttc gcttcctcgg
     3781 aactcctctt cgatatcaac ttcttccaaa atactataaa agaaattttc gatttctttg
     3841 tgattgccaa gtaaatccaa aaatgaaacg ccccgttcct ctaaatcttc atgaccaatt
     3901 agtacacgga tcgtattttc attaatatgt tccatttcca ttttgctaca cctcactttg
     3961 ccacaatgtt taatatagat tcattgtagc gaaatcagct taaatgtaaa gaaaaaaaat
     4021 ctcgctgtta agcgaattta ataaaaccag cggatttttc aacctttcaa gctatcttat
     4081 ttaactataa catttttggc agacgaatac tatatagccg acttttcagc taattttccc
     4141 tctctatttt tcgtgcaatc atcatcttct actacctttt tatacatcta atcaagaata
     4201 ctttttgtaa aaacaaaaaa acttggaaaa actatctttg taatagtctt ttccaagttt
     4261 cgtattatcc ttctataatc cagccatcaa ttgtgcttga cgtaattcta attgtcgtac
     4321 atcgcgcggt aggaaccgac gaatttcatc ttcattaaaa ccaacttgca gacgtttatc
     4381 atcaatcatg attggacggc gaagcaatcc aggattgttt tgcacaagtt ccaataattc
     4441 ttgtaacggc agatcatcta aatccatgtt cagtttttgg aatactttgg aacgtgtcga
     4501 gatgatttct tctgttccgt cttctgtcat ttgtaaaatc gcttttaatt cagaactgtt
     4561 caatggttct gaaaaaatat tacgttcaac aaatggaatc tgatgttctt gcaaccacgc
     4621 acgagccttt ctgcaggaag tacaacttgg ggaagtatat aatgttaaca acgtgcacca
     4681 ctccttttcg tgataagaat cacttttttg taacagaaga tcataataat ctcccatc
//
LOCUS       DAZAOD010000142         4685 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000142 DAZAOD010000000
VERSION     DAZAOD010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.144"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..973)
                     /locus_tag="ACHDPO_002721"
     CDS             complement(<1..973)
                     /locus_tag="ACHDPO_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFN3370281.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRI"
     gene            complement(1044..1340)
                     /locus_tag="ACHDPO_002722"
     CDS             complement(1044..1340)
                     /locus_tag="ACHDPO_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370282.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            complement(1333..1626)
                     /locus_tag="ACHDPO_002723"
     CDS             complement(1333..1626)
                     /locus_tag="ACHDPO_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFN3370283.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1772..2323)
                     /locus_tag="ACHDPO_002724"
     CDS             complement(1772..2323)
                     /locus_tag="ACHDPO_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HFN3370284.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2497..2796)
                     /locus_tag="ACHDPO_002725"
     CDS             complement(2497..2796)
                     /locus_tag="ACHDPO_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HFN3370285.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            complement(2823..3131)
                     /locus_tag="ACHDPO_002726"
     CDS             complement(2823..3131)
                     /locus_tag="ACHDPO_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFN3370286.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            complement(3248..4207)
                     /locus_tag="ACHDPO_002727"
     CDS             complement(3248..4207)
                     /locus_tag="ACHDPO_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFN3370287.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            4351..>4685
                     /locus_tag="ACHDPO_002728"
     CDS             4351..>4685
                     /locus_tag="ACHDPO_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFN3370288.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKAD"
BASE COUNT         1361 a          890 c          730 g         1704 t
ORIGIN      
        1 caatacgttg agaaattctt ccatctgtat aaacacggaa ttgttttcca ccagccattg
       61 ttgtatttcc attatcatcc gttacaatat taattgaata gtagcttcca ttttcatctt
      121 gcattagatc tttcatatat tcatttgtgc taattaaatt agtatttgat gcatttttat
      181 caggagaatc atacaaccat aaagctttat tatttagtac agtttcttta gcagcttccc
      241 aacttgaaat tgctgagcta cttgtagatt gtgtcgttgt agttgttgct tgttgagtag
      301 attcttctac tactggagtt tgaggagttt gtccattcac aatatcaatg aaaccttgtt
      361 ttaactgttg gttctgagtt tcattgaagt acatgtagtt tttatcattg ccttgatttt
      421 gttgcgttaa ataaacttta ggttgtccat tttgaaagcc aaagaaatat acatgctgcc
      481 ctaaatattc tccagtttct acatcagaat aaactgctac taaattgaaa tctgcatgac
      541 cagttccatc ttctgaccat tgtacggtaa ctggtgcttc attgattgcc attttccaat
      601 ttccatcaat aactgcactt ggtaaaggcg taccatacag acttacattg ttctgaggat
      661 tgtagctttt atattcttga cctaatgtct ttccccattg tgggacaaaa attgctagtt
      721 gagtagattt ctcactatcc cacaaagtat ttttaacctc ttcagaagaa gattcaatga
      781 ttgaactttc acttgtactt gcttccacag attgtttcat ttctgttgta gtttgttcag
      841 ttgattgcgt tttacttttt ttagcctcaa ttgttgtatc agtttctaca gtctctttag
      901 tcctcgtatt ctcagatgta caaccagtga ataaaatccc cattccaatt agtaataaca
      961 accatttttt cattttattt ccccctttca atttctccct cgcgtactta ttttatcagt
     1021 caattaatct caatggtgtt catttagtta atcctttccc aagaatgtcg atagccagca
     1081 tgacaacgat ctcttccttg agggctttca gatggattaa aactagtaga aatttccctt
     1141 ccacatcctc tacagcgata agttctcatt atttttgggc tattagtatt atttttctta
     1201 gttagagcta tgagtccaac tatgattacc ccaactgtct taattacttt tcctttatct
     1261 atattcggat gcgcaagcat atatttatat aaccaatatc caccgtaaat taaaccacct
     1321 aatacaatca gcttagccat gtactcgtct cctttctttt tgtttaatta ctttttgaat
     1381 ccatcttgca gagaaaccat aaacttctgt caattgacgg atatctacag ttttttcctg
     1441 ttctatcatg ttttcgattc tttttctaac taactcacga tcgtacattt tcattggaaa
     1501 agaaatctgt tgccctcgaa aagcaagata aaattgatag agcaattctg aatccagttc
     1561 catttcctca aaaaagtcat tcatactttt ataagagtta ctcaaacaag tttcatcaat
     1621 ctccatctac acaccccctg ttatttttta cataatgaaa atagcatatt actgggtaca
     1681 ttgataattc atataacatg tatcatcaca tgtattttta aagtcaaaaa gcatgtaaaa
     1741 ctacttataa gtaacataag aaaataaaat gttatttttc ttgaaataat aattgactat
     1801 ctgccaattg ccattcatta cgaacatgaa tacttagtgg gtgggataac ttaccttctg
     1861 catttatcaa tactttggtc atcttttttt gtttcgcact caattgatcg taaatggtct
     1921 tcgcttgttc ataagccact tgactcgtcg ctgtaatcga accacaagca aaaataatgg
     1981 tgttgatttt cttttctgtg aaaacagttg ttaatatttc caaagattgt tcatcatttc
     2041 cacgaggaaa tacccgagga cttttcgctt ttgtatacga aaaaagattc acagcaataa
     2101 aaccagtaaa tcctaattgt cggatattct tttcgattaa taacatactc aaatcattcg
     2161 taaatggttc tgtatctgtt ggacgaatag taatgactac cgctaattta tcttccgctt
     2221 cttttccttt gatcgcccat tgtcgtttga aaacatagcg atgggtatga tgaggatctc
     2281 gccaaacttc tgtttgtgtg gtcactaatt ctttttcaat catctctttt tctcctatgc
     2341 taatttttgt tcaagcaatt caatcaccat tgccgttata agtgtcaata ctagttgaaa
     2401 atatttcata ttctttctcc ttttttcttc agaatttgat gaatcgctgt aaggatatct
     2461 tctaaacatt tcgcaatcat tctcaaataa tcgatcttat tcattcgttc ctccaatctg
     2521 actccaaacc aatcgtcctt ctaccagtaa cccacgaaca aattctcgct ggctggtaat
     2581 atctgtaatg aaataaacta catagtcttt tccatcttct ggtgcgcaat aaatataaag
     2641 atgtgtcatc actaaacgtg gtagagtaac atcttcagga agcataccca tttcaatttc
     2701 ctctttttcc atcgtaacgg attcatagcc ccactcttca ggagtagtga ctagctgtgc
     2761 acacttttcc agtacttcga tagccgtttc taacaagtcc tttcgttcct ttcttttaga
     2821 tatcagtatt cttctggtaa taacatcgtt tgatactcac ccgaatcaat gacccatatt
     2881 ttttgagaca ctgatttcaa acgaagctta ggtgaaatca gatactcttt tcttgcttct
     2941 ggttcttctt gacgatgaac caacttttga tttccttttt ccgtagaaaa ttcaaagatt
     3001 tgaagatagt ctaaatgaaa ttgcttttga acgttttgat cgattagatt ccaacataaa
     3061 gcttgtaatt ccaccggcaa actgtccatt actccctttg tgacataacg ttgtccttta
     3121 ttttgaaaca tttcttttcc ctcctttgcc ataaaaatag cccaatcttc tattaaagaa
     3181 gattgggctt catggatata atatatattt gatattcaat ttgattcatt ttatactatc
     3241 tgatttgtca aattaagcta gacaatatgt ctttatctat gcagctcaaa aatacttcca
     3301 atggtgttcg ataatttaat gattttcttg gaatatggtt tcttttcgag gcaacggatt
     3361 gaataaaggt ttcatccgtg tccctaaagt ccattgtttt aggtaagcca tctcgtctaa
     3421 gcaagccgtt tgagtgctca tttagccctc tttgcgaagg tgttcctgga tctgcgaaaa
     3481 agatggcaat atcgttcgag ttacttatag atcgccagtt ggaaaattct tttccacaat
     3541 caaatgtcat ggatttaaac aagtgtttag gcatggattt gaaccaatca tttaacctgt
     3601 tttcgatatc ttcggctcgt ctgcctgtcg gtttcaaagt aataataacc ttggataaac
     3661 actcaaccaa tgtaataaca gcgctcttgt gtttaactcc cacaatggtg tcgacttcga
     3721 gatgaccaaa ttctttagtc aggtgtggat agagactgtt ccgttcatga atcgttctgc
     3781 gaaaggcctg ttttccacgc ttttcttgat gattattcgg tttacgtttc cccttcatag
     3841 gtaacgactg tgtgtcaaaa aggccttttt taaacatccg atagagtgta cgaacagaac
     3901 aatcaattgg aaactcgcca cggccgataa tcacatcggg tgaccatcct tgagctacct
     3961 tttcttgaac atatgttgat tgttcatcag ataaaacggt tgaacgtcgt ccacaacgag
     4021 atttattttg tttgtattga cggtaataat ctagcacttt ttttccttgt ttgagaaacg
     4081 aataaacatt ataaatggtt tgtctagagc gatttaaact ttgtgcgaca agagcgacag
     4141 gtttctcgat attgaaataa gactctatga ttactagttc gtctgttgta agatgggtgt
     4201 aagtcatttg tactcactcc ttattaattc tttggtcgga actattttga gtgtagcaca
     4261 aatgatcttt ttagttgtct agcttaattt tacaatcgac gttttaataa attgtgatat
     4321 aatgaagtat aactttttag ggagtgtact atgaattttc aagataatag accattatat
     4381 ttacaagtag aagcttctat acgtaacgat attcgtgaaa aaaaatatct tccaggagag
     4441 caattaccta cagaagaaga attatgtaaa atttatggag taagtaagat taccattcga
     4501 aaagctttta aacttttagc agaaagtgga acagttgaac gattaagggg gaaagggacc
     4561 tttgtaactc aaaaaaaaga aagtttaaaa ttagctggag ttcatggatt tagcgattct
     4621 ctttctaccc gaggacataa aattagatat actgttttac attctaaaat tataaaggct
     4681 gatga
//
LOCUS       DAZAOD010000143         4618 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000143 DAZAOD010000000
VERSION     DAZAOD010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.145"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(52..522)
                     /locus_tag="ACHDPO_002729"
     CDS             complement(52..522)
                     /locus_tag="ACHDPO_002729"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFN3370289.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(681..1139)
                     /locus_tag="ACHDPO_002730"
     CDS             complement(681..1139)
                     /locus_tag="ACHDPO_002730"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFN3370290.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1310..2455)
                     /locus_tag="ACHDPO_002731"
     CDS             complement(1310..2455)
                     /locus_tag="ACHDPO_002731"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFN3370291.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2468..3385)
                     /locus_tag="ACHDPO_002732"
     CDS             complement(2468..3385)
                     /locus_tag="ACHDPO_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFN3370292.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3813..4376
                     /gene="efp"
                     /locus_tag="ACHDPO_002733"
     CDS             3813..4376
                     /gene="efp"
                     /locus_tag="ACHDPO_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFN3370293.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1446 a          844 c          873 g         1455 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tcttttttta tttttattaa gttaaagaac
       61 ggattcaatt gcagcggtca ttttcaatgg agaagtttgt ggtgcaaatc gttcgattac
      121 tttgccattt ctatcaatca aaaatttagt aaaattccat tttattgctt tagtgacagt
      181 accaggagct tcatttttaa gataagtaaa aagaggatct gtattttctc catttacgtc
      241 aatcaattga tgcataggga aggtaacgcc ataagtggtt ttacaagctt ctgctgcttc
      301 agtcgctgaa tctagctctt gtttaaattg attggaagga aagcctaaga taaccagacc
      361 ttgtgtctga taagcttggt aaagttcttc taattgttta aattgaggtg ctagaccgca
      421 ttttgttgca gtgttaacaa tgattatcgg tttgcctgca tattttttca atgaatagac
      481 agtgccgtct tctaaagtag tttcaaaatt ataaatagac ataaagtttt ctcctttcta
      541 ttttatataa taaaaagagc gctaaactga aaactagcta tttgttttcc cgtttagaac
      601 tcttttcaga caataaatat ttaataaaat acgaagataa gatagctata ttgcttctca
      661 tctttacgtt cttttagaaa ctatgcttct acttcagacc attcatcgcg ttttgctaaa
      721 aattcacgag ccaaagcttg tgcaccttct agtgtatggc tggcagccca gccacattgt
      781 gtttcattgc ttgcaggtac ttcagtagct tcaagaacat ctttcattgt tgcttcaaga
      841 acatctaaaa tgtcttcgta gctttcatga ttcaatacag tcaagtaaaa gcctgtttgg
      901 catcccattg gagaccagtc tacgatgtaa tctgcgtgat tgcggattag ttcggcagtc
      961 aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt ctttatttgg ttgtttaaag
     1021 cggacgtcgt atttaatgat gacatcgcca tgcgcacccg tttttcgatc agctacacgt
     1081 acataaggtg ctttgacttt tgtatggtca agattaaaac tttcgacatt cattctcatt
     1141 tgtaagactc ctatctgttt gttcattcgt tttgatgctt ttcactaaag aattatttag
     1201 tgaaatttac aaaaacgtct ttctacttga ttctaacact tatcgtttcc aaggtgtagc
     1261 aatctgaaat attttttaga tttttctgct aagtcgttta ttgggacttc tagttcttga
     1321 ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg accatactca attcctacag
     1381 aaagacggat caagccgtcc tttatgccag cctcttctcg tttttctttt ggaatagacg
     1441 catgagtcat gacagaagga atttccacta aactttctac gccacctaaa ctttctgcta
     1501 aagtaaatag ttggagtgat tcaacaaatg gaatagcaga ttcttcattt tttaaagtaa
     1561 aagaaatcat tccgctaaag ccgctcatct gctgcttagc aactccatgg agttcatgat
     1621 cgggtaatcc tggatagtag accttttcta ctgctggatg agaaaataga aaatcagcta
     1681 ccacaaaagc atttttttga tgttcctcca tacgaacact tagtgtcttg attccgcgct
     1741 gaagtaacca gctatcttgg ggaccaagta cggctccgat agcattttgg taaaatccga
     1801 tctgatcggc tagatcttta tggttagaag tcactaaacc agctactaca tcgctgtgtc
     1861 cgcctagata tttggtaccg ctatggacaa cgatatcaga accgagatct aaaggtcttt
     1921 gaaaataagg agtagcaaat gtattgtcag caataactat caatccatgt tgatgagcca
     1981 gagtggcact tttttctaaa tcagtaatct ttagaagcgg attgctaggt gtttcaagat
     2041 aaagtgcttt tgtattgggt ttgatggatt gttctatttt atcaagatta ctcgtatcta
     2101 tgatcgtgta ctcgagacca tttttagtaa gaactttgtc aaatagacgg aatgttcctc
     2161 catagacatc atctcctaat aagatatgat cgccagcttg aaaaagagaa aaaacggcat
     2221 gaatcccaga aagaccagaa gaaaaagcga atcctcgaac accgccttcc aaatcagcaa
     2281 tcagttcttc caatgcaaaa cgagtaggat taccagatct tgaatattca tattgtttag
     2341 gctggccgac gccatcttgc cgataagtgg atgtttgata aataggtaca ctgacagctc
     2401 ctgttgtggg atcttcactg atgcctccgt ggatcaattt tgtttgaatg tgcatgtttc
     2461 tttcctccta taagtaaatg ttttttgata aatagcggtc tgctgcgtct ggaaaaatcg
     2521 taacgacacg atgaccaggt ggtaaacgac gaatttctct taatgctgct gcaaaagccg
     2581 caccactcga acttccaact aatagtcctt gttctcgtgc taactgccta gtatagttaa
     2641 acccttctac atcagagatt gtctcgatct gattgattga aaggggagaa agaaacggcg
     2701 gaatgaattc tacaccgata ccctcaattt cgtgaggggc tggatcacca ccatttaaca
     2761 cagagccctc tggttctaca ccgattattc gaatgtcggg atatttttct ttcaaaaagg
     2821 tagaagttcc agcaaaggtt ccaccactcc caattcctgc tacaaaacta tggatatttt
     2881 ctttgatttc atgaaagatt tctggcccta acgtatgata gtaagcagca ggattatctt
     2941 tattttcaaa ttgaagaggc agatagctgt ttgatatctc ctctgcaagt tttttacttt
     3001 tgctgatggc accgatgatt ccttgctcac taggagaatg gatgatcttt gctcccaatg
     3061 ctttcatcaa ttgttgtttt tctaagctaa acttctctgg aacaacaaaa accgttctta
     3121 atttgtatgt gagtgcggcc agagcgatcc caattcctgt atttccggca gttggttcga
     3181 tgatcgtcgt tttttcattg atttttcctt gggcaaatcc ttctttgatc aaataactgc
     3241 ccaatctatc tttgatactt cctccaggat ttaaatattc tagttttgca taaatagcag
     3301 aacctttagg catagaatag tgctgattgt caaagcgata aagcggtgtg gaaccaatag
     3361 cttctgtaat tgtcgagata atcatgtggg cctcctaaaa aaagataata aaaaaaggag
     3421 ctgactatta aatcagctcc ttgaaagaca tagagaaaaa ttgagtagat aaaaagataa
     3481 gttacctggt actcattcta tgaagggcaa ttaatagaca tgacaaatag tatgctgctt
     3541 ttatgcacca tacaacagca acgattcaat tgtttttggt tgctgactgt catgtgtatc
     3601 cctccaagta aaatttttat taacgatagc atgaaaaaaa ataaaagtca aaggcttgaa
     3661 agaaaaaaat atttcgatag catcgtttac ccgtgtttat ttttctgaca aataggcatg
     3721 agaccttaaa agatagagaa tactctagtt ttctggccgg ttgtctgata caataaagtt
     3781 gattatgata aagaaaagaa ggagcaaaaa taatgatctc agcaagtgat ttaagagccg
     3841 gtatgacttt cgtacaagac ggcaaactga ttaaagttct ggatgcaagc caccataaac
     3901 ctggtaaagg aaatacagtt atgcgtatga aactgaaaga tgtccgttca ggtgcaacat
     3961 acgacacaac gttcagacca gaagaaaaat ttgaaaaagc acatatcgac acaaaacctg
     4021 tacaatattt gtacacgatg gatgatacag ctttcttcat ggatttggaa acatatgagc
     4081 aatatgaaat tcctgtagaa acagtagaag aagaaatgaa atatatccta gaaaacatgg
     4141 aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt tcaattacca acaactgtcg
     4201 tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc aacagtcact ggttcaggta
     4261 agccagcgac aatggaaact ggcttagtag tcaatgttcc tgacttcatc gaaacagatg
     4321 aattgttgga aatcaataca gcagaaggtt cttatgtaaa acgtgcgtca aaataattcg
     4381 ctaacggatt gataagaatt tgaaaacaga gcttgacctc ttgaaaggca gatcatcgga
     4441 tctgcctttc aagaggtttt ttgtggaatc agcaaattga aaaataaaaa agtatttgat
     4501 tttatttata ttttgaaaga tgaatggcaa aagctagaga aagaaaaaac tgcacttatt
     4561 tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc gaactattcc gaactata
//
LOCUS       DAZAOD010000144         4590 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000144 DAZAOD010000000
VERSION     DAZAOD010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.146"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            186..2855
                     /locus_tag="ACHDPO_002734"
     CDS             186..2855
                     /locus_tag="ACHDPO_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFN3370294.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3560)
                     /locus_tag="ACHDPO_002735"
     CDS             complement(2946..3560)
                     /locus_tag="ACHDPO_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3370295.1"
                     /translation="MINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKAMH
                     MVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPGIE
                     KRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTIIK
                     ITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="ACHDPO_002736"
     CDS             3680..4219
                     /locus_tag="ACHDPO_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370296.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGEMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="ACHDPO_002737"
     CDS             4216..4554
                     /locus_tag="ACHDPO_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HFN3370297.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1421 a          790 c          859 g         1520 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggagaaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgacatt
//
LOCUS       DAZAOD010000145         4511 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000145 DAZAOD010000000
VERSION     DAZAOD010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.147"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..1434
                     /locus_tag="ACHDPO_002738"
     CDS             85..1434
                     /locus_tag="ACHDPO_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFN3370298.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1562..2152)
                     /locus_tag="ACHDPO_002739"
     CDS             complement(1562..2152)
                     /locus_tag="ACHDPO_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFN3370299.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2299..3651
                     /gene="brnQ"
                     /locus_tag="ACHDPO_002740"
     CDS             2299..3651
                     /gene="brnQ"
                     /locus_tag="ACHDPO_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFN3370300.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            complement(4125..>4511)
                     /locus_tag="ACHDPO_002741"
     CDS             complement(4125..>4511)
                     /locus_tag="ACHDPO_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFN3370301.1"
                     /translation="DRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLI
                     ENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDT
                     YNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT         1299 a          812 c          870 g         1530 t
ORIGIN      
        1 aaattttgga atcttagttg tgtttttcag aaaactctct taatatggaa gtaattaaac
       61 ttttttagtt aggatgattt aaaaatgaat gaagagcaag aactgcagcg tggactgaaa
      121 aatagacatg tccaactgat ttctattggc ggagcgattg gaacggggtt gtttttaggt
      181 tccggaaagt ctatccagct agctggccct tcgatattgc tcgcctatct tattactgga
      241 tgcatctgtt ttttcattat gcgtgcgtta ggcgaacttc tgttatcaaa caccaataac
      301 cattcttttc tggattttgt tgcagaatat cttggcaaaa aagcggcttt catcactggc
      361 tggacgtatt ggttctgctg ggtatcgatt gcaatggccg atttaacagc catcggaatg
      421 tatgtacgct actgggcgcc tggtgttcct cagtggcttc ctgaactgat tgcattaggt
      481 cttcttcttt gcttgaatat ggtggctgtc tcattgtttg gtgagttaga gttttggttt
      541 gcattgatca aagttgtagc gatcattgcc tttatcctcg taggagctta tatgatcctc
      601 acccactata cgacagatat tggcacagcc agtatcacga atctatggtc tcatggcgga
      661 ttctttccaa ctggtgcaaa aggatttatc ttagctttcc aaatggtaac ctttgctttt
      721 gctgggatag aattagttgg attagtcgct ggagaaacag aaaatcctga aaaagtgttg
      781 ccggaagcta tcaataatat tcctatcagg atcatcttat tttacttagg atctcttttt
      841 gtcattatgg caatctatcc atggaacagc ttgaatccag ataacagtcc atttgtagaa
      901 gtattttcgg aaattgggat cacgattgct gcttccttga tcaatttagt cgtattaagt
      961 gcagcagctt ctgcctgcaa cagtgcaata tatagtacag gacgtatgct tcgttcttta
     1021 gcgcaagaag gcagtgcccc taaaaaattc aaaaagttaa caacacatca tgtgccaggg
     1081 aatgctttga cattttctac tatcgtcatt ttcatttctg ttatcttgaa ttacgtgatg
     1141 cctagtgaag tattcacact agtaagcagt attgccacta cttgtttctt gtttatctgg
     1201 agtatgcttg tctacacgca catgaaatat cgtaaaagta tcctcggcaa aaaagctcat
     1261 tcatttaaaa tgccgttgta cccatttagt aattatctgg tatttcttta catggccttt
     1321 gtgtgtgtcg tcttgttcct aggaaaagat acgagaatcg ctttattact aacacctgtg
     1381 tggttcttgc ttctattact aatctatcat atgaaatatg aacgtaagaa gtaagaaagt
     1441 agttgtgaca gaagtggtca gcttcgagaa ataagaagga atttacgaaa attgcttctt
     1501 aaatttttgt gaaatttcgg cttatttctt ggagataaaa gcttctgtcc cagcctcttt
     1561 tctatttccc cggaaacaac cgctgataat aggcatctgc ttttttatag gaaaaaatcc
     1621 aaataccaga tacaaaaaaa cgtccgaata acccgatcaa cggtacaaaa aagacaccgg
     1681 caatcaagca taagttaatc atcatggaga taagacttcg acggtccttt gacaaaactc
     1741 tcacgacatg ggaatctggt ttatttgctt tcatgatttg cctcatcaag ataccaaaag
     1801 aaaaactcca catcgtgtat actaagacat aagccatctc aggccaaaaa gcttcagggt
     1861 tacgcccgac ccaactagta acagaaggac ataaagtcag ccaaaagagc aaaaagatat
     1921 tcgaccagac cactcggtaa ttaattcgtt ctgccatctg aaatatacga tgatggttca
     1981 cccagatcac cgcaacaaat ataaagctga tggtataagc taataatgta tttcggatga
     2041 cccataaaga atgaaagcta gatgtattag ggatcttgat ctctaataca agaactctca
     2101 aaacaatggc taccactcca tcagtaaatg cttctaatct cgactttgtc acgatgattc
     2161 ctcctcagat gattcagcgc ttttatttta tcacttacgt tattaaataa ccatcgtttt
     2221 atatagggaa ttttctgaaa attgttgcat atttttcgaa attttgttac ttttaaaaaa
     2281 accgtaaagg agttatgtat gacaaaaaaa ttatcattta aagactatct ttttataggc
     2341 tccatgcttt tcggtctatt ttttggtgct ggaaatctta tctttcccgt tcatttgggt
     2401 caagaagcag gcgctgctac cttttgggcg aatctaggtt tcttggttac cggtatcggt
     2461 cttcccttct taggggtgat tgccattggt gtatcgaaaa gctcaggtgt atatgaatta
     2521 gcaaaacgga taaatcaaac atatgcgatg gtttttacca tcttgcttta cttagttatc
     2581 ggaccgtttt ttgctttacc tcgccttgca accacatctt tcgagattgg tttagcacca
     2641 tttatcgatc ctagcagaca gacgctatat ctagcaattt tcagtattgt attttttgtg
     2701 ctggcttggt ggttttcaag aaaaccgaca aagatattag attatgttgg aaagttcctg
     2761 aatcctgcat ttttggtttt attaggtgct ttgcttctcc ttgctttttt gaatccacta
     2821 ggttctgtaa atcaagcgcc tattcagcca aattatcaag agcatgcttt tttcacaggg
     2881 tttactcaag gatataacac attagatgcg cttgctgctt tagcatttgg gatcatcatt
     2941 gtcacaacaa tccaaaacat gggtgtaaca aaacctgctg aaatcgctaa agacacgatc
     3001 aaatctggtg cgatcagcat tatattgatg ggaatcattt atactttgct cgcttattta
     3061 ggtgctatga gcttaggtag ctttgctcta agtgaaaatg gcgggatcac gctggctcag
     3121 attgctgatc attatttagg tacttatggc agtatcttat tagcatttat cgttatatta
     3181 gcttgcttga agaccggtat tggtttgatt acagcttttg cagaaacatt cacagatttg
     3241 tttccgcaaa gaaattacgc attctttgtt gcacttgcta gtatccttcc ttgtttagcg
     3301 gcaaacgtag gcttgacgaa tatcattcaa ttttcgttgc ctgttttgat gttcatctat
     3361 ccattagcaa tgacactgat tttactagtg ttagttggtc ctttgtttaa gcagcgtacg
     3421 gctgtttatc gaatgactac ttattttaca ttgattgctt cgatttttga tgggttgaac
     3481 gcttgcccag aaactatcaa acaaacacct attgttcaaa atcttttata tgttgcggaa
     3541 agctacttgc cgtttttcaa attggggatg gggtggatcg taccagcagt tatcggtttt
     3601 gttatcggac tgatttggag tttcgctaag aaagaagaag tagcagattg ataaaagagg
     3661 ttgtgaaaga gacgttcagc cttgagcaat aaaaagtaat tttgaaaaat ggcttctcac
     3721 atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg tttattgaga
     3781 ggtcgtgaaa aagccgctta gtttcaagta ttaagaaata ttttgtgaaa atggcttctc
     3841 acatttttgc ataaatttga cttaataccg agaaactggc ttttgaacac cgtttattga
     3901 gcgtctataa actgacctga gtattagaga aacaaaacgg caaagtagct ccatatactt
     3961 tgccgttttg ttttgaacta ataccgaaga gaagctgatc aaacaacatt tcttttataa
     4021 tatagatttt agacatatat atgatataaa aatagttttc gcaaaaaaac ttgggagcgt
     4081 caataatttt gtgtaaataa attgtcctcc tgcaaaataa ttagttactc agtaaacatt
     4141 gaaactaatg tatcggttac ctgttgaaaa cctttatggc ttctgtttag aaatttttga
     4201 ttgtatgtat caaaaatgct gactagaaag cgttctagtg attcttcatt ttgaaactgc
     4261 tcttttctac ggctgtatct tttaatttgc ttattgaaag actcgattag attggttgag
     4321 taaatggttc tacgaatgct aggtggaaaa tcataaaaag ttaataagtc ttggttttct
     4381 atgagtgact gcgtcacttt aggatagttt ttcttccatt tctcaatcat gccggataag
     4441 aaggtattcg cttcttcttt tgagttagct tgataaacag ccttaaagtc atcacagatt
     4501 tcttttcggt c
//
LOCUS       DAZAOD010000146         4450 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000146 DAZAOD010000000
VERSION     DAZAOD010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.148"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..927)
                     /gene="murB"
                     /locus_tag="ACHDPO_002742"
     CDS             complement(<1..927)
                     /gene="murB"
                     /locus_tag="ACHDPO_002742"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFN3370302.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSL"
     gene            complement(1000..1920)
                     /locus_tag="ACHDPO_002743"
     CDS             complement(1000..1920)
                     /locus_tag="ACHDPO_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFN3370303.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2033..2785
                     /locus_tag="ACHDPO_002744"
     CDS             2033..2785
                     /locus_tag="ACHDPO_002744"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFN3370304.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3649..4182
                     /locus_tag="ACHDPO_002745"
     CDS             3649..4182
                     /locus_tag="ACHDPO_002745"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFN3370305.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1313 a          873 c          792 g         1472 t
ORIGIN      
        1 taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca cttctgtttc
       61 taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca attcaatata
      121 atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt cagagacttg
      181 tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac ctgtatagtg
      241 tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct gttttgattg
      301 acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc ctgtttgcaa
      361 actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt gacgataaga
      421 aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca aaagatccac
      481 ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat aaaccgctcc
      541 accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt ctgccaaagc
      601 tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg ttcctttgac
      661 atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc catcttgaac
      721 gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc ggcaataatc
      781 gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag ctggtccacc
      841 tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa tcgtggctaa
      901 gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc aaacgtcctc
      961 attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat gacggtagtg
     1021 atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt gtttaagcaa
     1081 ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca ttggctcaaa
     1141 cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt ttccatcagc
     1201 atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt tacttgttac
     1261 ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag ccgtttgatt
     1321 ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc ttatctggta
     1381 ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa gatgtaaaaa
     1441 caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt tttgcaggtg
     1501 gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa agcgccggtt
     1561 gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt cacgaacttc
     1621 atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt ctagacattt
     1681 tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt cgattttttc
     1741 ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt tttgaattct
     1801 ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt gttttttcgc
     1861 ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac caatcttcat
     1921 ctactttcct cctggatcat ttagttactt tcatcttaca ccattttttt ctaaaatgag
     1981 gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt tattgaaatt
     2041 tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt tagaagtttt
     2101 tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag caggacaaat
     2161 tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa aaggctattc
     2221 cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa tgggtatcga
     2281 tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct ttcttgtaac
     2341 ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat tagaatggga
     2401 agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca tcgtgtgtgg
     2461 ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga atcaaaaaaa
     2521 tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata acgggtttat
     2581 cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt ggaactaccg
     2641 attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga cgagcaaaga
     2701 tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca gtgatcattg
     2761 tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt ttcgagtatt
     2821 aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat aataccgaga
     2881 aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg catcaagtaa
     2941 taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc ttattaccgc
     3001 agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca ctgcatcaag
     3061 taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg ggcttattac
     3121 cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct gcactgcatc
     3181 aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg ttggacttat
     3241 taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc agcgtcctga
     3301 cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat tttttgagct
     3361 aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa aagtcgccta
     3421 ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca taaatttgac
     3481 ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg agttcaaaaa
     3541 ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa atttatttgc
     3601 ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat gaattttgtt
     3661 gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct tgcgctagtc
     3721 atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc tgagactcct
     3781 tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg caatgcgccg
     3841 aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg tttagtcgtt
     3901 gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta ttatcatctt
     3961 gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct gtttcctgaa
     4021 tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt agatcatcac
     4081 catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca agaaaaaaaa
     4141 ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac ttatgaaaca
     4201 cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat ttcaaaaaat
     4261 agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag gagaacaccg
     4321 tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca gccaaacaaa
     4381 aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa gcttttggac
     4441 accgtttacc
//
LOCUS       DAZAOD010000147         4349 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000147 DAZAOD010000000
VERSION     DAZAOD010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.150"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            61..564
                     /locus_tag="ACHDPO_002746"
     CDS             61..564
                     /locus_tag="ACHDPO_002746"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370306.1"
                     /translation="MENSIYLVTEPNTQLKDQDNLVSELSRQKQVYKFLELLLNSASY
                     LNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISIK
                     EYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRLG
                     LGIINGE"
     gene            661..2910
                     /locus_tag="ACHDPO_002747"
     CDS             661..2910
                     /locus_tag="ACHDPO_002747"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFN3370307.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            2913..4088
                     /locus_tag="ACHDPO_002748"
     CDS             2913..4088
                     /locus_tag="ACHDPO_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3370308.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4091..>4349)
                     /locus_tag="ACHDPO_002749"
     CDS             complement(4091..>4349)
                     /locus_tag="ACHDPO_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFN3370309.1"
                     /translation="GITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQN
                     FNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1515 a          633 c          791 g         1410 t
ORIGIN      
        1 atgtaataat ataaacataa taaaacaaaa attatccaaa tctaacatag gagggtggat
       61 atggaaaatt ctatatattt agtaacagaa cctaacactc agctgaaaga tcaggacaat
      121 ctagtcagtg aattgtccag acaaaaacaa gtttataaat ttttagaact cctcttaaat
      181 tcagctagtt atctgaacga agggataatt actaaaaaga tgaatccttt tgttcgtcaa
      241 acaattgaaa taatacgtga gaatgcgtat caaaaattat ctgttaaaga tattgctgtc
      301 agtctatcga tacacgaaaa ttatttatca cgattgttta agaatgatat gggaatatca
      361 ataaaagagt atattagtga aatcaaaatt tctattgcaa acgatctgtt atcatcaact
      421 gaatattcaa tccagcaaat cagtgacaag ataggattct caacagtaca atctttttct
      481 aaagccttta agaaagcaaa tggtgtttca ccgggagtat atcgaaaacg tagattaggt
      541 ctaggaatca ttaatggtga ataaactaaa catttgattt tgataaatat tcgttacttt
      601 aaacgcttac tatttatgtg agcgtttttt ataatgcaat aaagaaacgg aggagagctt
      661 atgtataagg ataatgaaat gaatattatt tatcgatcag aaaaccaaca atttcatttg
      721 tttaatcagg agataagtta catttttaag atatcggaag atggtaaatt attgcattta
      781 tattatggtg agaacttacc agataatgac tatagtcatc taattgagat gcatcatcgg
      841 cctatgacaa cctatagaaa tgaaaacgat ttgctatatt cgttagagca cttaaaacaa
      901 gaatttcctg aatatggtac aacagatttt agacatcctg ctatttcatt actacagaaa
      961 aatggctctc gcttatcaga ttttgtctat caagggtacg aagtggaaga aggaaaacct
     1021 aaactagaag gtttacctgc tacctatgtt gataataatg atgaaagcaa aacattgaaa
     1081 gtttatattt tagattcagt tacaaatgtt caagtagaat tattatatac aatttataga
     1141 gattatcctg ttattactcg tagcgcgcga gttatgaata aaggaaaaga tattcaaata
     1201 atcgagaata ttagcagttt atcattggat ttacccgatg caaattatga atggcaacaa
     1261 ttatctggtg cttggggtag agaaagaact attaagtcgc gtactttaca acaaggaatt
     1321 caatcaatcg aatctactcg aggtatttca agccatcagc ataacccatt tgttacttta
     1381 aaaagaaaaa atactgatga aaatcaagga gaagctattg gtgcagcact agtttactca
     1441 ggaaacttct taattcaagc agaagtagat acatgggatg ttactagact acaagttggc
     1501 atcaatccat ttggatttaa ttggaaactc aatccaggag aaatatttac agcaccagaa
     1561 gcgattctgg tttattcaag taagggttta aatgccatga gtcaaacttt tcatcaacta
     1621 tttagaaaac gcttagctcg tggtaagtgg cgagaaaaag accgtcctgt cttaattaat
     1681 aattgggaag caacatattt tgattttgac gaagaaaagt tggtaaatat tgctaaaaaa
     1741 gcatttgatg ttggtattga attatttgta ttagatgatg gctggtttgg agaaagagaa
     1801 aacgattgtg caggattagg agattggcat gtaaatccta aaagactacc tagaggaatc
     1861 ggcagccttt cagaaaaaat tcgtagtttt ggtatgaaat ttggtttatg gtttgaacct
     1921 gaaatggtga ataaggatag tgagttatat cgcacacatc cgaattggat tatttctaca
     1981 cctaatcgaa aacctaatca tggtaggaac caatatgtat taaattttgg gttagatgag
     2041 gttgttgaaa atattttcga tcaaatgtgt aaaatcattg atgaatcaaa cttagattac
     2101 attaagtggg atatgaatcg tccattgact gatgtatttg acagtcactt gtcagcagat
     2161 caacaaggag aagtattcca cagatatgta ctaggcgtat atcgcttata tgaaaaactt
     2221 ataacaaaat atcctaacat actatttgag tcttgttcat caggtggtgg gcgctttgat
     2281 cctggaatgc ttcactatgc acctcaagct tgggctagtg atgattcaga tgcaattgaa
     2341 aggttaaaaa ttcaatatgg aactagtatg ctgtatcctc tttcgtctat tggtgctcat
     2401 gtatcaattg ttccaaatca tcaaacaaac cgtataacac ctataaaaac tagaggaaat
     2461 gtagcttttt ttggtgcatt tggatatgag cttgacttaa atgaattaag tgaaggcgat
     2521 ttgaggattg taaaagaaca aattgccttt tataaaaaat atagaaccat aattcataat
     2581 ggtacttttt atagactatt atcaccattc gatgatgata atcaaaccgc gtggatggtt
     2641 gttagtcatg ataagaaaac ggctattgtt gctcattata aaacattaaa tgaggtaaat
     2701 gctccttacc gccgactgaa attaaaaggg ttagataatg acggacttta taatgtagga
     2761 caaaatagtt tgcgatctgg aatggaattg atgagagcag gactagtctg ttcagatgca
     2821 tctagtggac aaataaatga tcagaatcga cgcccagaaa catttgattt tgattccaag
     2881 atttgggtta taacacagga ggaaaagtag agatgaataa ccaaaaaagc ttacttcaaa
     2941 aaggagcaat cttaagtatt tcactaatgt taacaagctc tcaagcaatt aatggtgtta
     3001 ttccacaaat gaaacagtct ttggggatat cacaaagtca aagtgaactt ttaggaactg
     3061 caccaagtat aactgttatt ttgtttatct tattatctag ttactttgcc aaaagaatag
     3121 gaatgaaaaa gacaataatt ttaggtttat tattagctgg tataggagga attattccag
     3181 tatttacagc taccttccaa accgttctta ttagtcgagt aatattaggt gccggtttag
     3241 gagtatataa ttcattggct gtgacatata tcagctcttt atactctggc aatactagag
     3301 caacgctatt aggtattaga aattcaatgg aagctttagg tcagacaatc cttatttttc
     3361 ttgctggagt tttagtgaac attaattgga cggcttcgtt tttagtctat gcaattgcgt
     3421 ttcctgtagc tctcttattc gcgctaaaag ttcctgaaat tagagatgaa aatagtgaca
     3481 tacctgaaaa tcatgtaaaa gaaaagatga atccaatggt ttttgcccta gttctatttg
     3541 caatcttact cgtaatgaat agtattgcta tttctgtacg atttgcatca attgcaactg
     3601 aaattaaagg ggtaaacttt aatgctagta actatttagc tctaatgcct atcttaggaa
     3661 tactagcagg atttatgttt ggaccaataa ataagtggat aggaaaagga accctatact
     3721 tgggaattat attctttata atttcaaatt tgttaattgc tgtgtcaaac ggtaatatga
     3781 cgttcctgct aacgggttta tttttatcaa gtataacagg atcatggtgc ttcccattta
     3841 tctttagtaa cttagataaa gtcactacaa agaatacaat taattttgct acttcattga
     3901 tttttattgg ctgtaatatt ggtaatttta tagctcctat tgctatgcaa ttagcacaat
     3961 ttctaacaag aagtacaaat ttgactgctc cattttttgt attcgcagga atatttattg
     4021 tgatcctatt tgtaacattt tttgcgacaa ataaaaaaaa tactagagta acccgtggtg
     4081 ctagttaatt ttaatatcct aaagaatatc tcaaagttcc ttcaaaacgt cgttgtgctc
     4141 gacttaatag aacactgtaa gccagtaata tgctttcaaa tctactctct agccctttaa
     4201 cagaacgtga gttgaaattt tgacaaccta atttttctaa ggaagaaaaa acagtctcaa
     4261 ctgtttttct ttgttttcca agtaagctgt ggtctagttt ttctgattta tccatgtttt
     4321 tacgtggcgg aacggatata gtaatgccc
//
LOCUS       DAZAOD010000148         4341 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000148 DAZAOD010000000
VERSION     DAZAOD010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.151"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(94..579)
                     /locus_tag="ACHDPO_002750"
     CDS             complement(94..579)
                     /locus_tag="ACHDPO_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HFN3370310.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(581..1252)
                     /locus_tag="ACHDPO_002751"
     CDS             complement(581..1252)
                     /locus_tag="ACHDPO_002751"
                     /inference="COORDINATES: protein motif:HMM:NF037286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370311.1"
                     /translation="MSRFSINVVEVDDYSEITDILKSIRKKYLRKTIFISGSAVDYTP
                     FTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGNSIVSGVLKQRRNLRKNNIQDVLS
                     LRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLESGEIVTADGMIEEFELSVQNENI
                     VVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQALEKLDTEGEVDKKVEQIVSLIN
                     SIQED"
     gene            complement(1515..2708)
                     /locus_tag="ACHDPO_002752"
     CDS             complement(1515..2708)
                     /locus_tag="ACHDPO_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3370312.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(2792..2992)
                     /locus_tag="ACHDPO_002753"
     CDS             complement(2792..2992)
                     /locus_tag="ACHDPO_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFN3370313.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(3416..3649)
                     /locus_tag="ACHDPO_002754"
     CDS             complement(3416..3649)
                     /locus_tag="ACHDPO_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370314.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(3656..4087)
                     /locus_tag="ACHDPO_002755"
     CDS             complement(3656..4087)
                     /locus_tag="ACHDPO_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFN3370315.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         1089 a         1072 c          839 g         1341 t
ORIGIN      
        1 attaactgat aaaaaaatat ctactattta aagatacagg gataagtaag taaaaaaata
       61 acatgtcatt agatagtaga cagttccaac tctttattta ccttttttgt atgctgcact
      121 gtcaatccaa gttcctaaat tgttgtatcc atcatcactt atataatcat attggccatc
      181 aataatttcg tcaaaccaca aatattctcc atctggtttt tgcccaatta ttttaattac
      241 tgattgacta gtagttgtca tctggttaaa atcttttatt ttacctatat taacggccaa
      301 aatagcattt cctcgcttat aactctcctg gatttcatat ttaacatatt ctcgatcaag
      361 agtttcttta cctatcagca ccacagtcac tgatgttcca attaattgat tatctatcca
      421 gttttttata gcaatatctc cattacgttt aactttctca aattcagcct tatctacaaa
      481 accagcttcc tttgttcctc gcaaagtcca gctgtttcta actaccattg ctcttgttac
      541 atctgcataa tggaaactaa aaaaaaccct tctcaccata ttaatcctcc tgaatactat
      601 ttattaaact gacaatttgt tcaacttttt tatctacttc tccttcagta tctaattttt
      661 ctagcgcttg aaatttactt tttaaggaat catcaaaata atcactgaaa ttctcttgaa
      721 tcttatcaaa caaaacctta cttgcacctt tggtaaatcc aatcggaact actatatttt
      781 cattttgaac agataattca aattcttcaa tcattccatc tgctgtaact atttcacctg
      841 attcaagttt gtttccaaaa acaaaaatac taatcccaga ctctgcaata atgttttctc
      901 gatatcttct ccactcatga ggcatatcaa ggggaagtgg tcttaaagaa agtacgtctt
      961 gtatgttatt ttttcttaaa tttcttctct gctttagaac tcctgaaaca atactattac
     1021 caattccaag tccgtaacct gatactattc tataaccgga ttcagaaagc ctatatgcta
     1081 atttctcgac aaattttaat cctttcgatt cagatgtaaa tggagtataa tcaacagcac
     1141 ttcccgaaat aaaaatagtt tttctcaaat acttttttct aatacttttc aaaatatcag
     1201 taatctcaga ataatcatct acttcaacaa cgtttatcga aaatctggac aaatcattga
     1261 tttgtagtct tctttttgtc agttcataat tatatctctc ttgatcaaaa aaatcctcag
     1321 aatcgacaaa attttccttt aaaattatat gggattttag attatctttt tagaagttct
     1381 tgaatgtcgg tatagcccgt gtttccgggc ttttccggca tttttgatat tgttagatac
     1441 ttacaaatgt tcttattacc tctcaccatt tccccctcaa aagtagtaaa tggagtagta
     1501 aaaccggcct tgtgtcaggc tgccagccgt tccatttctg cccttgcgga atcgaatgtg
     1561 gcgtgtgcat aatagttcag cgtcatggtg atattggaat gtcccataat gtactgcaag
     1621 gctttggggt tcattcccgc attggctaac cgggtgcaga atgtatgacg catagcatgg
     1681 ggcgtcgtcg ttttcggcaa cgcttcttca tggctcttgt tgtacttctt cacaagcctg
     1741 ccaaacatcc cgccataatc taccgccgtc atgggatagc cgttctgttt gagaaacagg
     1801 aaattggcat acccgtcaat aatgaacggc tttgcacctt tgcggttttt tatcactcgc
     1861 tggaacgcct gatacacttc ctcattcatg gggatttttc tgacgccgct ttgggtcttg
     1921 ggttcgtcaa tatagtaacc gacgccggta tttctcaaaa gctggtggct cacgatgatt
     1981 acccggtttt caaaatccaa atctttgtcc gtcagtccgc acagttccga aatgcgaagc
     2041 cctgtcccca gcagaataac gattgcgtca taatgctttt ggtaaacctt atcaccttga
     2101 ataaaggaca gaaaactttc ttcctgtgct ggtgtaagag gcacctttgg ttccgtatcg
     2161 tcgtccagaa cgtcactaag ctggaagtca aacgggtttt ttcggatgca atcgtcctgt
     2221 atggcggtgt aaaaagccgc tttcagggaa cgcttgtcgt tattgatggt cttataagaa
     2281 aggccctttt ctttcatccg aagcgcccat tcctttgcgt cggacagctt cacactgtca
     2341 atcgggcagc tccccagccg atcttgttcc agaatacgca tcagccgttc ccggcccagt
     2401 ttggtgttgt gcttcacatt gccccggtgc ctgatctgct tggcgtagag ctggcagacg
     2461 gtcattttct tgccgatggt gtctatcccg tcgtcaaggt ctttctggat ttctttctcc
     2521 ttttcccgga gtgaaatatc ctcccgttta cctgccgggg tcttatccgt aggcactaac
     2581 ttccatgagt aaacaaactg cggttttcca aaggtatcaa catatttgta agcatatcgt
     2641 ccgtcttttc tctggctctc tccagaccgc aaaacgcgat ttttgctgtc tcgtcttttt
     2701 tctgacatct cgtcatgctc ctttccatga cggaaagagc cgcatatatg cttataaatt
     2761 attataacat atctgcggcc ctttttcact attagattgt gtccaaagtg tcaattattt
     2821 tctcaaactg cttgcgtttg atctggatgc ggttgccatt cataatgacc cagccagagg
     2881 ccggattttc ctcggccagc ttacgcaatt tgttttctcc gatacggaaa tatttagacg
     2941 cttcctcaat cgtcagcgtg tatttttccc aaataggcac atcatggttc ataatgcagc
     3001 cccctttcac aaattcaaag gtttgtgtga tttaggggca tagacggacg gctgctggca
     3061 cagctccacg ggactttcac ccccgcgtgg ttctcacgcg gccctaccca ttgcctgcga
     3121 cgcttttaac gctcggactg tggctataag ggagtatcat agtcctgcct gtacgtcgtc
     3181 gcccgcaagc cgccacgctc acattgcggc gtggtgttcc tcgctccgct tttcccgtag
     3241 ggaaaagtat catggcgcac cagccgtccg gctcggcaca gacagaatgt gtccgtatgc
     3301 cctatgatgc gccgccgtta tcttgcgggc atatttatca aggtgcgatc aggccaccgg
     3361 gaaaacaccg aaacggggaa agggtaagcc gtttcatgct gccggggccg gttcgtcagt
     3421 tcgtgacgat agcgtggatg agcttgattt ccagacggcg cttcatggcc tcgtccagac
     3481 acacatgcgg atagccgttt tcgtcataga gcgtccgggt acacagcttg ttcatgtaac
     3541 cgctgtaata ctgcaaaacg cgctctacgg ctccggcatc cccagcgcgg gcggcctcga
     3601 tcaccgaaag gggcaaaagc tcaatgccct tgtagttcgg gttcttcatc cgcgtctaac
     3661 ctcccttcgg catcaacgcc tttagctgtt tccgcagctc cgataaggta tttgtcctgt
     3721 gccgctgaac ggcactccgg gacattccca caaggccgcc gatctcacca tctgccatat
     3781 ccagaacaca gtgcaggatt aaaatactct gctccatgct gggcagcgcg gcaaaggctt
     3841 cggcaacaag ctcattgttg atatgtaggt catagccatg cgacgaaaac gtaaagctgt
     3901 cgctggggta gtgatctact gtacagagct tgtccaaatc tgcctgtgac aaagagctta
     3961 gtgacacttc acggtcacgg cggcgcttca tttcagccaa gtagcttttg gcctcgttac
     4021 gcagtaccgt cttgcaaaaa gcatcgaaca tgcaccgcgc ttcatagtcg cgggggatag
     4081 catccatctt ctcaccccct ttctgtgggg gacttaggtg gttctctccc tttccgctaa
     4141 caagactttg acaaggccgc cagctacccg ctaaatacct cctttttgaa aatttctcaa
     4201 aaaatttttt tggggacagc cgggccgcaa aagacgacaa aaatcgcccg gcaggtcgca
     4261 aacctaccgg gcgagaaaat gctttgctat gctgctgatt tacatggtat agtacatact
     4321 cataaccgga atagccctgt g
//
LOCUS       DAZAOD010000149         4335 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000149 DAZAOD010000000
VERSION     DAZAOD010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.152"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            127..579
                     /locus_tag="ACHDPO_002756"
     CDS             127..579
                     /locus_tag="ACHDPO_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370316.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="ACHDPO_002757"
     CDS             593..1282
                     /locus_tag="ACHDPO_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370317.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="ACHDPO_002758"
     CDS             1407..3758
                     /locus_tag="ACHDPO_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFN3370318.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="ACHDPO_002759"
     CDS             3838..4233
                     /locus_tag="ACHDPO_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370319.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT         1526 a          548 c          867 g         1394 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatt
//
LOCUS       DAZAOD010000150         4273 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000150 DAZAOD010000000
VERSION     DAZAOD010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.153"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            77..778
                     /locus_tag="ACHDPO_002760"
     CDS             77..778
                     /locus_tag="ACHDPO_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFN3370320.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1350..2366)
                     /gene="tsaD"
                     /locus_tag="ACHDPO_002761"
     CDS             complement(1350..2366)
                     /gene="tsaD"
                     /locus_tag="ACHDPO_002761"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFN3370321.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2363..2827)
                     /gene="rimI"
                     /locus_tag="ACHDPO_002762"
     CDS             complement(2363..2827)
                     /gene="rimI"
                     /locus_tag="ACHDPO_002762"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFN3370322.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2834..3376)
                     /gene="rimI"
                     /locus_tag="ACHDPO_002763"
     CDS             complement(2834..3376)
                     /gene="rimI"
                     /locus_tag="ACHDPO_002763"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFN3370323.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3360..4082)
                     /gene="tsaB"
                     /locus_tag="ACHDPO_002764"
     CDS             complement(3360..4082)
                     /gene="tsaB"
                     /locus_tag="ACHDPO_002764"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFN3370324.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
BASE COUNT         1262 a          914 c          738 g         1359 t
ORIGIN      
        1 tggtatgtta aaactttaca aattctttaa aaaaagtgac aataaatata gtgaacaata
       61 aggagaggac tttttaatgc gtgttaataa aatcgatttt cacttttcaa aactcagata
      121 tcaacctgat tttgaacatt tctcggatga agagttccaa cagatcaagg aacatactgt
      181 tcttcgttct tataaaaaag gacagatcct tttcgacgat ggtgatccca gacaacggtt
      241 gtatatcttg accaaaggac tcgttcgttt agaacgttat gatgaaagtg caacttatta
      301 ctactatgac tatgtgaata caaataacct ttttcctatg tcaggaatgt ttggagaaga
      361 gacctacact tatacagctc aagcgatgac tgatattgaa acattctacc ttcctgtttc
      421 ctactatgaa aaattagcac gaaaaaatcc cgaacagttg atctatatga tacaaaaaat
      481 ttctaaagta gttgaaatac atgaattgcg tatccaaatc ggattgacct ctagcgcctt
      541 tgaccgggta aaacaaaatt tattcatttt gaaagaagaa ttgggcgtac caacaaaaga
      601 tggtcatatc accattcctt atccgatcac cttaaaagaa ttagcagtga atagcggcac
      661 gacacgtgaa actgctggac aagtaatcaa acaactacgt gattccggac tgttagatta
      721 tgacaaaaag cgttttactt tctgtaagac agctactact ccagctatga gagaataacg
      781 cgaacaaaaa taagcagtga ccctgatatt tatcagggtc actgcttatt ttcctcccta
      841 aaacttctga aagatccggc agttttagat cactgggcaa gactcaaaga ttttctatgt
      901 gtgtttcagt tatgtaatat tcactgtttg caaaaaatac tgatagatta actagaggaa
      961 gcgtcttgtc ctcatccgac ctagattatt cgatattcct cgacaataaa cgattaatca
     1021 gtgagggcaa tcagaggaac ggataatgat gaataagctg taaaaaatag ggctttgaca
     1081 aaagcgtgtc acagccctta tttcgattaa acggtgtgta cctgtcaact cttcggtcac
     1141 aagtcataat gttcataaac atgaggagct gttttttgaa attgttcctt gtgaatcaga
     1201 gttaaacgac aggcttacga actcttgatt aaacggcgtt caaaagcttg catacgcggt
     1261 aataagaaca gccaggtcaa aaacatgaga agccgttttt cctgggctgt tcttattact
     1321 tgatgcaggg cagatttttc acaacctctt tattcagata aaaccaagct tggatcagca
     1381 ttcaactgat agctagcaaa atttcttttt tgcatttcca catgtgctgc tgctccaatc
     1441 attgcagcat tatctccaca aagtcgaaga gggggaatca ctagttctac ctcagggagt
     1501 ttagttgcca aagcatcctg caatccttca cgcaaccctt gattggccgc tacacctcca
     1561 gctacaatca gttgcttgac tggataattt tgacaagctc gaagtgtttt agtaatcaat
     1621 acatcgatca cacttgcttg aaagctagct gctaaatcat ttttgtctag atcttctcca
     1681 cgctgttgtg cattatgcac caaattgata aatgcacttt ttaatccgct aaaactgaaa
     1741 tcataattat cttcatggat catcgctcgt ggaaaatggt aattatcttt tccctgatga
     1801 gctagctgat cgatttcttt tccgcttggg taagaaagac ctaatactct tccaactttg
     1861 tcataagctt ctcctgctgc gtcatctctt gtctccccaa tgatttcata tgatccatct
     1921 tcttgcatat agactaattc tgtatgtcct ccgctaacaa gaagtgccat caatggaaac
     1981 tggaatggtt taaccagacg ggctgcatag atatgccctg ccatatggtt tacaggaata
     2041 agcggcaatt ggtgtgccca agcaaaagcc ttagctgcag aaataccaat cagcaacgag
     2101 ccgacaagtc ctggtccata agtgacagcg actgccgata aatcttctgc cgacacacca
     2161 gcttctacca gtgcatcttc caagcataag gtgatttgtt ctacgtgatg gcggctagct
     2221 acttcaggaa ctacgccacc aaaacgttta tgactgttta tttgagaagc aacgatgtta
     2281 gataagatct ctgttccatt tctaacgacc gctacactcg tttcatcaca acttgattca
     2341 atcgccagaa tcaattcttc attcatttca tcgtctccgt ttttaacttt ctgctcataa
     2401 tgatcgcatc ttccgtcgga ttgcgataat atgatttccg tttacctaat atacgaaact
     2461 tttctgattc ataaagtttt cttgctgctt cattagatag acgtacttct aaaaaaacat
     2521 gcagcgaatc ttttatttgt tccgtaatca gtaattgtaa caaatgccgt gcatgccctt
     2581 ttccttgttc tgaaactgca acagcaatat ttgtgatctc gacttcatct attactttcg
     2641 agtatccaat aaagccacag atctggttat cttcaactaa aagcagataa tcagagtgag
     2701 gctgttggat gtctgccaaa aactgcattt tcgtccaagg tgaaccatgt ggataagcat
     2761 tttcgctaat catccatacg cattctgcca agtacgcttc atcaaaatct ttttttctgc
     2821 aaatcaacta atctcactca ttttctaaaa gttttatcat atccaacgca tcttcttttg
     2881 tttcagtgta atatcttttt ttgatcgttg ttgcttgaaa acctaacttc cgataaagtc
     2941 tttgtgcatc ttgattactc atacgcactt ctaatgacat cgtctcacag cgattcatta
     3001 tagcaaagtt ctcgatttcg tcaataagca gcgaaccgat tcgtttacgc tgatatgccg
     3061 gtcgaacggc aatattcgtg atatggcaat ctaaaccgaa cgctcttgaa ccgataaaac
     3121 caatcattct tccattatca aagataccta gatatagatg aggaagcggt gacttcaatt
     3181 ctgatataaa ggcacttttt gtccatggca attcgccatt atagacttct cgttcgacat
     3241 ccagcagctc tttgatatct tctgtagtca attctcttag tacgtaacga cgatcgattt
     3301 gttcgattgt tttttctgta taaatcattt tatcttgaaa aaagcttctg gcatacgctc
     3361 taaatttttt caacataact ttcgtctcca ggtgtgtgcg tctccaacca tttttcttct
     3421 gcttctaccc gttttaaata gcgaggaaga aaagcttgtt tctctgcaac tggttcagct
     3481 aaagcaccta attgagccac agttacacca cttggaatat cccatgctgg aactgtatta
     3541 atcatcgcac taggcaatat ttcctttatt tcatagaaga atttgtgaca atcactcccg
     3601 acgaaataaa tagcttcatt cagcttttgt agttgtgtga acaaatcaga agcagaaata
     3661 tgtacatctt caagtacaat ttctaatcta ttttctttcc agcggtatgc cccagcgtat
     3721 acattttttc ttcgagcatc aaacatgggc acaataattt tatccacacc gatgcaatta
     3781 gccgcgatgg ttttcagact agatactcct actagctctt tatctaatgt ataagcaatc
     3841 gtttttgctg tcgttacacc tatacgaagc cctgtataag aaccgggacc atcagaaacc
     3901 gcgattcggt caatgtcttt tggacttatt tgaagatctg caaacaattg gtcgattgca
     3961 ggcatcagtg ttacactgtg gttgcgtttg atatttgttt gtatttgtcc aagaatttgt
     4021 tcgtcttcta ccacaccgat cgccaaagtt tggtttgcag tatctattcc taatgtaatc
     4081 atatatttga tcctttctgc tatgacattc tcgccttcca ttgtagcata cttttttatt
     4141 ctgaggatga aaataccaaa ggcaaaacta gtacaatgat acatgattat ctgctggcgg
     4201 gcaaattttg ccccttcctg aaacacaaaa aagctgcggt atcacttcat ttccccacag
     4261 cttttccatc ttt
//
LOCUS       DAZAOD010000151         4186 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000151 DAZAOD010000000
VERSION     DAZAOD010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.154"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..923)
                     /locus_tag="ACHDPO_002765"
     CDS             complement(<1..923)
                     /locus_tag="ACHDPO_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFN3370325.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYV"
     gene            complement(920..1144)
                     /locus_tag="ACHDPO_002766"
     CDS             complement(920..1144)
                     /locus_tag="ACHDPO_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFN3370326.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1141..1434)
                     /locus_tag="ACHDPO_002767"
     CDS             complement(1141..1434)
                     /locus_tag="ACHDPO_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370327.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1471..1608)
                     /locus_tag="ACHDPO_002768"
     CDS             complement(1471..1608)
                     /locus_tag="ACHDPO_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFN3370328.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(1610..2041)
                     /locus_tag="ACHDPO_002769"
     CDS             complement(1610..2041)
                     /locus_tag="ACHDPO_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370329.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2055..2549)
                     /locus_tag="ACHDPO_002770"
     CDS             complement(2055..2549)
                     /locus_tag="ACHDPO_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370330.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(2549..2998)
                     /locus_tag="ACHDPO_002771"
     CDS             complement(2549..2998)
                     /locus_tag="ACHDPO_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370331.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            complement(3002..3622)
                     /locus_tag="ACHDPO_002772"
     CDS             complement(3002..3622)
                     /locus_tag="ACHDPO_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370332.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            complement(3622..>4186)
                     /locus_tag="ACHDPO_002773"
     CDS             complement(3622..>4186)
                     /locus_tag="ACHDPO_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFN3370333.1"
                     /translation="NAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKE
                     EFERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGV
                     RHASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFP
                     IEEGALIIATVDDPKQNVFTLEKVGVI"
BASE COUNT         1127 a          922 c          653 g         1484 t
ORIGIN      
        1 acatagactt tcttattagg gaagttacgc atgttaaaag atacatgata gccaacattt
       61 ccagaagtat tataagcttg atttacatct gctctataaa ttccatcagc tcttactcga
      121 gctaattctt tcccagtatt gtaatccata atgaagatat actcgtattt atagttagca
      181 atgtgccatc cagctacatg caaatttgca ttttcgattt ctccaaactg atcaatgtgg
      241 gcgtaattcg ttccatctgt cagtgtagga ttagctgcac cagctcgtgt tggatcaatg
      301 acaggcttgt tttcagaagt tgttggattt tcatcggtaa atccatgagc taaatcatat
      361 gctaattttt ctttacttac gcccatttca gaaagataac cgtaaggatc tgtatgatcg
      421 ccccagatgt tttgtgttac ccataaatgc gatttgattc ccggttggtt ataaggagtg
      481 tccaacgtta atggaatacc atatttcatt gctgaatctc tagccaattc aacgtatgcc
      541 ttgtagtttt tctcaaacgt tgctttatca tgtgtgtgtt gtaactcaat ctgcacagga
      601 ctgttggcat tagcatacga accagcaccg tactgtacat aaccaggttg accgacttga
      661 taaacaattc cgccgtctcc cacaatataa gcagtataag cgctagtcca tgaacgttgc
      721 atatactgcg cttcattgcg tcctgttgct gtttcattag ccgtttcatg cagtaaaata
      781 tactgattat ttgctacttg tgagctacct tcatttgcgc ccaaattaaa ttcattgttg
      841 atagtatagg caaatccgtt aattggcaat aaaaaaagag ccgttaacag gctcatcgca
      901 gtaatagtaa ttttcttttt catttgtttc ctccttcttc gctttcagcc gagaacattt
      961 tgtaggttcg atttgataca cccaacacac tccctaaaaa cgcgccaaaa ccagtaatga
     1021 tgacaacaca gatatctgtg tactgccaat tgagcgcttt accaactaac cccacgaaag
     1081 tagctagtgc gggaataatt accagtgcga accattttag tacttcgaac gttttattat
     1141 tcattttctt ctctccctaa acaaagtttt gatttgttgc gtgtgttcca ccaatttttc
     1201 tgtatgtgta tctaatcttt catcgtgttt ctttagttct tcatgaatca tcaatcgatc
     1261 tgatttgctc gattctaaat ctttagtcag caaatctaaa ttgtggctta cttttgaaag
     1321 agtctcagta attttcgaga aagatgcagc aatcggtcta attactaata aaatcaaaga
     1381 aacgatagcg gttattgatc ctgctatcat tccccattcc cctaaattaa tcatgtgaca
     1441 actcctttac cttaaataaa aacgcatcaa ttaagatgcg ctcttatctt tattaatgat
     1501 tttatctgct tcttcgtctg taatgcataa tggaacgaaa accattactt gttcgttagt
     1561 gaaacagccc cagtcataca ttagtttgat atcttcatat gaatacatgt tacttcccac
     1621 cttgtaattg ttttttgatt tcttcgattt ccttggtatt ttgtacagaa gcaagcatcg
     1681 tttttgaatt caactgcgct aaactttctg acttttcttt caataagaca ttttcttgct
     1741 tgattgctac attgtttagc attgctttag aatttagctg tttcaattca tcattttctg
     1801 ccttcagcgt ttcgtataat gccttaatat tagccaattc atctacgcta tcaacagcat
     1861 tccctttttt ctcttcttca gtagctaact caacccactg ttttttatca aaatcaaatc
     1921 ttggtctcca gttaggaact ggtggtttaa tctctgtaca gttttcaggg atattttctt
     1981 gattgttcaa aatgatttgc tcgaatccgt aaggcttgat tgatttgtaa actactttca
     2041 ttagatttcc tcccttaaat tgaataagtg ataacaaatg aataagctga tccataactt
     2101 gaatttcttc tccatttaat ggctccgtct gcgccaatag atagttgagc actgttcaaa
     2161 gtagaacggt ctattgaccc aaccagttgt tcaaaactaa ttggtgtccg atagccttct
     2221 ggaacagtta aaataaccga atcattcccg ccactacttt ttccgtttaa agccacaaaa
     2281 tatatagaaa ctgtttttcc ttcacgataa agctttgctg tccctgtatt accgttagtg
     2341 acaaccagat ttaccacttc atatctgtta tcatcagtcg tcaaaacacg tttattattg
     2401 attgttacag aacctgaaaa attcttatgt cctgcaatgg cttggtctcc atctgtctgc
     2461 accaatgctt ctttaccatc aatagcttct acatgcgttt ttaagtattt agcaactccg
     2521 tcttctttta attgaacaat atcagccatt aaaccgtccc cactttctca aatgtaatat
     2581 tcgctaatcc atcaagtttc actttatcgg ttgctgacat taaacctgct gtcgtagttg
     2641 tagcattacc tggatttttc tgtgctccag ctgcaattcc atccaactta gttttatctg
     2701 tggacgacat caacccattt gctgtagttg tagctacagc tgtagttgtg gcatttattc
     2761 caggatcacc tttatctccc tttggtaaaa caaaattaaa tctagctgca gatgatgttc
     2821 ctacattcgt aacagaagcg gttgaaccac tagaaacggt tcctatggta attgttgctg
     2881 cttggccagg atcgccttta tctcccttca ccgttgttgg tttgccttct atagcattcc
     2941 aatgagtttg tggataaacc tgtacattgc tttgttttat ttttacgata tctgtcattc
     3001 tctatacctc cccaattttt tcaaaagtaa aatttggaat tctttcgttt gtgtaatttt
     3061 ctgcttgatt tacagcttct tggaattttt gatctacata tgactgattg acaccaccag
     3121 tcccactacc acctgtagaa ctaattgttc catcttcatc aatagtgatg ttttctccag
     3181 cagtataatt tttcagtgaa tcgagttttt cttttaactc cagcgaaaaa ttgacatcag
     3241 attgtctgac tgcagagact ttccctgtct catcaatcgt caataattca ccaactttta
     3301 tgccacccaa acggtcgata gtggcaactg gcaacacgta gtcaccttct ccactgttta
     3361 aaattttttg atacatttct gccgtgataa tgccgtcatc ttcttcactt gcatagggta
     3421 attctgtgag aacattctct aatcccaaat cttctttagt aatgacgacg gctccaattt
     3481 ttccattaac agataaaact gttgcttctc ctgctattat ttcttctaac ccaagaactg
     3541 cggaagcatg tgtgattgga aagaattggc gttgtacacc cgttttttca tccgtttcca
     3601 tcattcgttt agttttagcc attagatcac cccaactttc tcaagagtga acacattttg
     3661 ctttggatca tcaacggttg cgatgatcaa ggctccttct tcaatcggga atgctacagt
     3721 tccaactttt tcgacttcat gattatctga aaagagatca tcctgcaaaa tatcagtcac
     3781 ttcaatctcc ccgtattcaa tcgtgaaaag cgttgctcgc aatttctgat ataaatagtc
     3841 catatctgcc agcaaacgct ctgaaataga cgcatgacga actccttgaa tatctactcg
     3901 cgcatccgtt agttcggcta acatgactcc acctggatca atcgtcttta aaatatcctt
     3961 gattgattca aaccatgcca aatagtctga ttcttgtcct tctctccaat cttggaaact
     4021 gtgttcctgt tcttgtctcc aacgttcaaa ttcttctttc ctttcattca tccagtccgt
     4081 aaaatcgcct ttattttcat taataaagtc cgtcatatcc gcaattaaat cttcgattga
     4141 ttgccaataa gaacccattt ctccttctgt ttttgaaaca gcatta
//
LOCUS       DAZAOD010000152         4184 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000152 DAZAOD010000000
VERSION     DAZAOD010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.155"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1296)
                     /locus_tag="ACHDPO_002774"
     CDS             complement(<1..1296)
                     /locus_tag="ACHDPO_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370334.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTF"
     gene            complement(1394..1669)
                     /locus_tag="ACHDPO_002775"
     CDS             complement(1394..1669)
                     /locus_tag="ACHDPO_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370335.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            1901..2635
                     /locus_tag="ACHDPO_002776"
     CDS             1901..2635
                     /locus_tag="ACHDPO_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3370336.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            2674..3816
                     /locus_tag="ACHDPO_002777"
     CDS             2674..3816
                     /locus_tag="ACHDPO_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3370337.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         1502 a          713 c          629 g         1340 t
ORIGIN      
        1 aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt taccatagta
       61 agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac tttccttact
      121 atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca tttcctctag
      181 ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt caaaaagtac
      241 ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt tctctaatag
      301 ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa ctccaataaa
      361 attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc cagttttact
      421 ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta agtttttact
      481 tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct cattaaaaga
      541 catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt ctttgtcgtc
      601 attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc tccctgaatc
      661 actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag taatatctaa
      721 catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa aaaacattct
      781 attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt attcgtaaac
      841 agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa tcttgtattt
      901 ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat tatgaactaa
      961 attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac tcaaatctac
     1021 taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta ctctggtttc
     1081 cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa atgattgtga
     1141 tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat ctaaacacct
     1201 atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt tttctttatc
     1261 tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct tataaaattc
     1321 tgttaaagac taaaacatac agataataaa aacaaactct ttattactat atgttttagt
     1381 cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca gattttttaa
     1441 atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca tattttctaa
     1501 tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata tactctagag
     1561 tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc tctttcactt
     1621 gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata tttccccctc
     1681 ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt gctcaaaata
     1741 aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt catcgacata
     1801 cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat ttacaacacc
     1861 ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac gtccaccaat
     1921 aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa gaaagagtaa
     1981 aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa ttgacaaaaa
     2041 gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat tatcccgaat
     2101 tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag aagaatatat
     2161 tttgggaatt attctttata gagatagcat tgtactagat ggtataacat ttccagataa
     2221 aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt tagatacatg
     2281 gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta acaagacttg
     2341 taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag aagaattatt
     2401 catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta gcagtataga
     2461 agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag acatgtctta
     2521 tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac aaacgatttc
     2581 atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca tctagtggta
     2641 agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa gtacaaaaag
     2701 aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc acgaactggt
     2761 gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca aaaagattat
     2821 gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga tatgacattt
     2881 gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc ttcaacaatc
     2941 gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa gcttaaacta
     3001 tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag taaatatgaa
     3061 agttacgatt atatgagaaa acagactgca caaattttac gctacggggt tgcaatgcaa
     3121 tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga gtatgagaaa
     3181 aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt taaagatttt
     3241 ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat gagaaagagt
     3301 gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact acatgtcaat
     3361 aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa aacaagagct
     3421 tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa ctggaaatta
     3481 cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga gcaacatgtt
     3541 tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg gttaagatat
     3601 attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca tacacatgct
     3661 agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt agggcatgaa
     3721 aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc taagaaaaca
     3781 ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa atctggtcat
     3841 ttctagtata caggcaaaac aaaaaagcta gaacccttat atatcaaggg ttctagctcc
     3901 tataacaggt ttacccaaca ctgccttcca atgactcttt tgggaatcag aggaaagaat
     3961 caggctttat agagatattt catctaacaa attactttag actgacagta tatatcagca
     4021 ggtactgtca tcgggaacgt agccaatatc gtatccaaaa cagcaggtag agaagctatt
     4081 tgaggattca agttattcta tttcaaccat gaagttaagt tcattaaaaa taaagatagt
     4141 tggtatttca ataatttttg tatagagtta atcactttat tgat
//
LOCUS       DAZAOD010000153         4147 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000153 DAZAOD010000000
VERSION     DAZAOD010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.156"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            12..758
                     /locus_tag="ACHDPO_002778"
     CDS             12..758
                     /locus_tag="ACHDPO_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004564412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HFN3370338.1"
                     /translation="MKQTTQQRLNQLMSERNLKQVDILNMSLPLQKETGIKMSKSHLS
                     QYVNGKSSPDQHKLYLLAKTLNVSEAWLLGYDVPKEDKKNNIPSIETIYNQLEKPRQT
                     KVYNFAEQQLEEQNRGNVVHFPKKEKLPTIKNSASAANPTELVYGDTVVEEEEFERVP
                     NNADFAVPIIGDSMEPVIRNGQFVFVKEQPDVEDGEIAIVEIDGDGVTCKEVYKDYES
                     QTIILRSINELYEDRVVSPEQIRIIGKVVF"
     gene            834..1040
                     /locus_tag="ACHDPO_002779"
     CDS             834..1040
                     /locus_tag="ACHDPO_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HFN3370339.1"
                     /translation="MPSYVVLQVVLKEKFIGKGSQNLSELENTINRQCSKGYRLHTIS
                     TTNGGSKGFGGGDRIQATLVFESL"
     gene            1143..1796
                     /locus_tag="ACHDPO_002780"
     CDS             1143..1796
                     /locus_tag="ACHDPO_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370340.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQVTAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFFKYGIQ"
     gene            1932..2567
                     /locus_tag="ACHDPO_002781"
     CDS             1932..2567
                     /locus_tag="ACHDPO_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFN3370341.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAKNNVLQAQTGYFGTETVSIALHN"
     gene            2686..3897
                     /locus_tag="ACHDPO_002782"
     CDS             2686..3897
                     /locus_tag="ACHDPO_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3370342.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKASSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLKHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFENLLKKDIK"
BASE COUNT         1591 a          681 c          780 g         1095 t
ORIGIN      
        1 ggaggtataa gatgaagcaa acgactcagc aacgacttaa tcagttaatg tctgaaagaa
       61 atttaaagca agttgatatt ttgaatatgt ctttaccttt gcaaaaagaa actggaataa
      121 aaatgtcaaa aagtcatcta tcgcaatatg tcaatggtaa gtcatcgccc gaccaacaca
      181 agctttattt gttggctaaa actttaaatg tgagtgaggc atggttgctt ggttacgatg
      241 ttcctaaaga agataagaaa aataacattc catccattga aacaatctac aatcaattag
      301 aaaaaccaag acaaacaaaa gtctacaact ttgctgaaca gcaactcgaa gagcaaaatc
      361 gaggaaacgt ggtgcacttt cctaaaaagg aaaaacttcc gacaatcaaa aattcagctt
      421 ctgccgccaa cccgactgaa ttagtttatg gcgatacagt tgtagaggaa gaagaatttg
      481 aaagagttcc aaacaatgct gattttgctg ttcctattat aggcgattca atggaaccag
      541 ttatcaggaa tggacaattt gtatttgtta aggaacagcc agacgtggaa gacggtgaga
      601 ttgctatcgt tgaaatagat ggtgacggtg tgacgtgtaa agaagtatat aaggattatg
      661 agagtcaaac gattattcta cgctctataa acgaattata tgaagataga gtcgtctcac
      721 cggaacagat tagaataatc gggaaagtcg tattctaaaa aataccccag tcgtagttgg
      781 cgctccggct aggggttagt atttattatc atagtagaaa gaaggaaaag aatatgccaa
      841 gttacgttgt attgcaagtt gtattaaaag aaaagtttat aggaaaaggg tcgcaaaacc
      901 tatcagaact tgaaaacact ataaatagac agtgttctaa aggttatcga ttacacacta
      961 tttccactac aaacggtggt agtaaaggtt tcggtggtgg cgatagaatc caagctactt
     1021 tagttttcga aagtctataa acaaaaaaac acgcccaccg accaaagttt gtggacgtgg
     1081 gatgttaaac ctatagtagg cttctttaca acttattgta tcaaagaaaa gaggagtata
     1141 aaatgaaaaa agttagcgtt atgttgttgt taagtactgc tctgctactt tcagcttgtt
     1201 caaataataa aaaagctgaa tcaacagatg ccacttctaa ccaagaaaca aaaataagta
     1261 aaacaaaaga aacaactgaa accagttcat ctactagcaa atctacatct aaaacagatt
     1321 ctagttcaac agttacaagc tccaaccaag ttacggcgga acctagccca acagttataa
     1381 gctccagtca gagtacaatc caaaccgcac ctcaagaaga aacatatgaa cagatgaaac
     1441 aacgcacttt acagtcaact ccagctgatc gtgcaaattg gtccaacaaa gagtgggaag
     1501 ctttcggcgt ggccctttat gaaaatggat tgactacaga tgatgctggc aatattatca
     1561 gtcaagatca gaaagaacaa caagcagcat ctcaacaaaa tccagaagac caacaaacaa
     1621 gcgctcagca agacgctgac actttatcac ttactgattt tgttaacaaa tacgggatgt
     1681 cgcctgttgc atggaaagta cagaatggaa tgtctgaaga agaagcattg cgtacaacac
     1741 agcaaaagac ttccggtgaa gttcaattag gattttttaa atacggaatt caataatata
     1801 tttttatgcc ctactatttt gcctataatc tctaaaaaag ttataaataa aaaagcccgt
     1861 gctgcaacac ggactcatac ctcatttctg agatcacaaa tatattataa caagaaatga
     1921 ggaatattta aatggcaaaa aaagttatgg gtcaagatgg gaaaatgtat aaggttaaaa
     1981 aaccgtttta taaacgggta tggttttggg tattaatagt acttttgttt tttggtattg
     2041 gtggtgctct aagtggcggt gaaaacaaag attcagctac tgcaacatca acaagtacta
     2101 ataaagaaac tacaaaagaa actacaacaa aagaagaaaa gacttataaa atcggtgatg
     2161 acgttgctgt agggaaaatg gaatacaaag taaactccgt tgaagtagta aaacaagttg
     2221 gcccatctgt acttcctact aacgcaaaag acactttctt agtagttgac ttatctgtaa
     2281 aaaatgcagg tgataaggct gtgactgttg atagctcatt cttcaaatta aaagcagatg
     2341 gaaaaacttt cgaagctgat tcggctgcat ctatgtcggc aaatcaagat gaaaatggta
     2401 atatcactaa ctctttcttt atggaaagct taaatcctga tatgcaacaa actggtaaaa
     2461 tagtttttga tatctctgaa gcccaagcaa atgcaaaaaa taatgtattg caagcacaaa
     2521 caggttactt tggaacagag acagtttcaa ttgctcttca caactaatta gtataaaaaa
     2581 cacgccccac cgaccaaagc gagcgtgttc taagaaagaa acaaacctat acgataggct
     2641 tctttatagt acctattgta tcagagaaag agagctgatt caattatgtc agaagtaaca
     2701 ggatacttag aacaagtaga caacgaaaca tatagactaa gagctgtatt aggatacaaa
     2761 cctgatggct cggcaaaaag aaaaagcaaa actataaaag caagtagtaa aagagcggca
     2821 tataaagaat tgaacatctg gttagagcaa ttcgaaggaa tgaccgatga ttcgttggat
     2881 ttgttcaata taacttttgg tgaattttat agaaaaatat ggctttcaga ggccgaaaaa
     2941 aatttagagc caaagtctta tcataactat aagcgaatga tcgagaatag atttcttgat
     3001 aaatttgatt ttatccctct aatcgatatc aaaccataca tgataaagaa aattgttgtt
     3061 aatgctcaaa gaatcaatac aaaagatcct gggagaaact ctgataaacc tttatcaaga
     3121 aatacaaagc ttcgtatgtt atacgccgtt aacaacttat ttttgatggc taaaaatgag
     3181 tacggagcaa ttaaagaaaa tcctgtggaa aatgtaaaaa taccaaaaga aaaaggcgta
     3241 aaaaagaata tcgaagaacc ttattcggaa gaagaaattc atgcaatgct aaaagcagca
     3301 tttgaggaaa gcatagaaat taaaacttta attgttctag catttattac aggagcaaga
     3361 caaggagaaa ttgcagcttt agaagaaaaa gatattgact ttgacaaaca agaaataaga
     3421 tttcatcagc ggatttcaga agtggatgga aaatcagata ttcggttgct gccaggtttg
     3481 aaaaatgatg atgatgaaaa aatagtaacc ggtcctgctt atctatttga tatgttagat
     3541 gaattaatca aagagaataa aaagattcgt tggaaattaa atataaagaa attaaaacac
     3601 tattttatat ttgatacaaa acaagatgga actttgccac gtggaagtta tctgtataag
     3661 aagttcaaac gattcaccaa acgtcacaat ttgcgtcaca ttcgttttca cgacattaga
     3721 catacatcag ctacctattt gcttagcgat cctaatatga ctccaaaaga gcttcaaaaa
     3781 cgattgggac accgagattt taatactaca atgaatgttt atggccatgt cttacgcaaa
     3841 gaaaaagata cagcaactac agcgtttgaa aacctattaa aaaaagatat aaaataacac
     3901 taaaaaatta tattttcggg tataaactcg ggtaggatat acaaaaactt gggataattt
     3961 gcggtatata agcatttaaa aatgctgtaa attcgcttat cttcatttaa aataccatta
     4021 aataacgaac tcttaatcag cgggtcgcgg gttcgagccc ctcacggccc attgggtgcc
     4081 aaacccacgg aacaggtaaa tgttggtgcg aaagcatttc gaaaacattt acgctgttct
     4141 tttttta
//
LOCUS       DAZAOD010000154         4131 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000154 DAZAOD010000000
VERSION     DAZAOD010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.157"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(360..1286)
                     /gene="glsA"
                     /locus_tag="ACHDPO_002783"
     CDS             complement(360..1286)
                     /gene="glsA"
                     /locus_tag="ACHDPO_002783"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFN3370343.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(1309..2736)
                     /locus_tag="ACHDPO_002784"
     CDS             complement(1309..2736)
                     /locus_tag="ACHDPO_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFN3370344.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(2767..3981)
                     /locus_tag="ACHDPO_002785"
     CDS             complement(2767..3981)
                     /locus_tag="ACHDPO_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFN3370345.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         1285 a          888 c          745 g         1213 t
ORIGIN      
        1 tcggctagac tttctagatc gtgaaggatc gttggtgtag tcacccttag agaaatagct
       61 gtttgttcga tgtctatttc ttggaattca aataattgtt cacacagata cacttttcta
      121 aatatatttc gctcgatgta attttccagc attcctgata cacgcctcca gtttttctta
      181 tgattttatt taatcatatc tgtaaatcgt atttttgttt cctttttatt tagaaaagcc
      241 ctttcaaaaa ccaataaaaa aagaaactgg gacaaaagtc aaacaagctc acaatttcag
      301 cctcattgta ggtagctttg agccgtttgg acttttaccc cagcctcttt caagaatggt
      361 tattcaaaga tgtcagcgtc tagttctttg actacatctt tcaacaattg gataccagct
      421 gcgctgttac caaatggatc tagtgccggg ctgaagacac ctatgccgta acgatttggc
      481 acagctgcca tcaacccgcc gcctacaccg ctttttgcag gtacaccaac atggacggaa
      541 aactctcctg attcatcata caaaccagca gttgtcataa ttgatttgac gattgtagca
      601 ctttcttcag taatgatttg tttgccattc caaggagcaa ttcctttatt tgccagcaca
      661 gcagctaatt ttgctatgcc tgtagcggtg acattgaggg agcattgtct gaaataagca
      721 tcgagtatct ccggtacgtc tccttcgatc atttgattac ctttcatata gtaagcaaga
      781 gagcgattga tatcacctgt tcttgattca gaatgataga tttcttcatt caatgtgata
      841 ttaggatcat cacagatctc tttcataaat gacaagattc gctcaaattt ttcatctgca
      901 tctttaccgg caatcaacga ggttgttgca atcgctcctg cattaacaaa aggattcatt
      961 ggatgtttgc gatgattgat ttccatattc atgatagaat tgaaggcaaa accggttggt
     1021 tccgtgttga ttgtttgaaa gactttttct attccgttgt ctttgattgc taataacaat
     1081 acgggaactt ttgacatgct ttcgatggca aagcgcacat cggcgtctcc tccctcaatc
     1141 agttgttttg tatccaaatc ataaatcgcc atacctaatt gtttgggatc cacttcagct
     1201 aatgctggaa tgtaatccgc cacttgtcct gtttgataat agtggaaatt ttttccaatc
     1261 aattgttcta attcttttac ttccatttga ataaccagct ttcatttttt atttttctgc
     1321 atgctggaat ttatgacggc atgcgtagat cgtaaatgga ataactaaga cgataagata
     1381 agaaacaatc agaatcgttt cataaatccc atgctgtcca gctgcgatac tagcaggtgg
     1441 aacaaatgag atacaaaaag caaaaagtga agtcaaaaga cctaaacaag caacgattac
     1501 ttttacaact tttccgcctg gaacctgata ggctctttca agactgtcat ctttaaaaac
     1561 cagcttcaaa tagcccgcga aaaacataaa gtacaacatc aggtagatta caacagtcaa
     1621 tgacatcgct gcaagaaatg aaagattatt ccccccgccg cttaatgtaa agacggctgc
     1681 ccagattgtt gcaacgatcc catttgcgat catcaaatga gcaggaacac cgtgtgtgtt
     1741 ttcttttgca aaatattcag gaagtaatcc ttcttctgct gctacgtgaa gtgcttttga
     1801 aggagaggtt acccaagaag caatttctcc gatgacacct aaacaaacaa gaatcgcaag
     1861 aattttcgca atccatgcaa gatttggatc aatgtgtctt aataggaatt ctaacgattg
     1921 aatcacccct gtattaagag acaaaccatg ttgaggtact gtagtagcga cggtcaatcc
     1981 gccaaaagta tctaaaatga ttgccagaat aaccaataca aacattgcta atggataatc
     2041 ctttttaggg ttttccattt catttgcatg actggcagat gtttctacgc ccatatatgc
     2101 taaaataaag gaaacaaaaa caaccagcgt aggcaatttc gaaaaatcag gaatcaatgt
     2161 tttcatagac agtatcgttt gtagtggagc gcctgaagcg acataatgga tccctaagcc
     2221 aaacaagact aatgctggca acaagatacc agctacaaaa ccgatccgag caatcaatga
     2281 agtgtatttg gttcctttta actgtgagag taaaatagcc cagaaaataa tcaataggat
     2341 tgccaatttc agatatttat tgttttgtat agcaccaata cccgttgcat aggataatgc
     2401 accagttaag aaatacagca tggtcaagta gccaactgtt atctcaaacc attggaaaaa
     2461 gattgcggca aaaccgaatc gttttcccaa tgtgcgactg acccaagtat agacaccgcc
     2521 tttttcccat cctttcaccg ttgccatctc tgctgcgcac aatgccacag ggataaacca
     2581 tagcaaaccg cctaataaca agaaaaatac taagctgaag cctgaggtcg cgaatgtggg
     2641 atattcatat aatgaaacga ccattgagat ggtcatagcc aaaaagccaa agaacgttaa
     2701 tttttttgca ggaattttcg ttttgctttg ttgcatgaat cttcctcttt tctatttgaa
     2761 tttgtttcaa ttgagtttgt tgccaaagaa gaaaaagtcc aatccttctt cttgttcttc
     2821 ttttgtagta gtgatcgttg taaagtgcat cgccgatttt aaaatcactg ttgtcagcac
     2881 ataggcatac acggcagtaa tgatgacacc aatcacttga atccctaaga agtaccagct
     2941 gcttggattc gttagtaaat ggctgttaga tgcaaagatc cctatcagaa tcgtacctgt
     3001 gaatccgccc atgccatgaa caccccacac atcaagtgca tcatcccatt gtttcttttt
     3061 acgaaaatca acagcagcat gacagacgat acccgcaatg atcccaatca gcatggcact
     3121 ttttgcttct acataaccgg cacaaggcgt aatggctgcc aatccagcaa cggatcctgt
     3181 tagtacgtcg acaaaatcaa agccatttcc ttttactttt gcaatgatca gccaagtaat
     3241 catcgcaaat gcaagagcga tgaatgttga accaaatgca ttgactgctt gttcatctgc
     3301 tcgaagtgca ccaccggaat taaaaccgaa ccagccaaac caaagcagtc ctgtaccgat
     3361 agcagctgcc ataagactgc tatgctgact tctttctcct aaaggaatct ttctttgacc
     3421 aagtgtgagg atacatgcta aagagccgaa tccagctgtc gtgtggatga ctgctccacc
     3481 agcgaaatct ctaaatccca tctgatccaa aaatccgcca ccccatatcc agtggcaaac
     3541 agggaaataa atcagcagat tccaaaaaat aacaagtata atatagcctt ttaaattcaa
     3601 tctccctgca aaagctcctg tcatcaaagg aacggtaatc acgataaaca tcagttggta
     3661 aagaaagaac attaaaaatg gaatcgttgc accatgaaac atgttgggga agcttgtaac
     3721 atgtctcatc aaaaagaaat ctgccgggtt tccaataaca ccgccgatat cccgtccaaa
     3781 ggccaatccg aatccaccaa atacccacat aatcgttgtt atcccaacgg agagaaaaga
     3841 ttgagacatg atcgttagta tattattctt ccgtgctaat ccgccgtaaa aaaaagctag
     3901 accaggagtc atcaggcaaa ccattgctgt acataaaatc atgaatgctg tatctcctgt
     3961 attgataggt aatgtattca tttttttcgc ctcctttcta cgattacgag tataaaagaa
     4021 ggtgtagttg tttttttctt ctgttttttt gaattaatac ttgcatttat aaaagacaga
     4081 caattaataa aagcttgatg tgttgtgctc tttttcgttt ttcacacaaa t
//
LOCUS       DAZAOD010000155         4127 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000155 DAZAOD010000000
VERSION     DAZAOD010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.158"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            47..1348
                     /locus_tag="ACHDPO_002786"
     CDS             47..1348
                     /locus_tag="ACHDPO_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFN3370346.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1375..1635
                     /locus_tag="ACHDPO_002787"
     CDS             1375..1635
                     /locus_tag="ACHDPO_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFN3370347.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2634..3869)
                     /locus_tag="ACHDPO_002788"
     CDS             complement(2634..3869)
                     /locus_tag="ACHDPO_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFN3370348.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1185 a          666 c          862 g         1414 t
ORIGIN      
        1 gtcatgcaat gaatggttca tattttattg aaaaggagtg gttttagtgg aaaagctgat
       61 gaaatgggtc gaagagaaac ttgtcccacc aatggcaaaa attggtacac agcgtcattt
      121 attagcaatt cgtaatgggg ttgtttcaac attgtcattg attttgattg ggacattttt
      181 tatggtcttt atcaatttac cgtttcctgg atggaatgaa tttattgccc cttattcggc
      241 aacgattgtt ttacccttta ggatgacgat gggattgatg gctatttatg caacttttgt
      301 tatgggttcg gatctagcta aatcatatgg attagatagt gtgacaggtg gtatattatc
      361 tttaggaacg ttctttatgt tacaagttcc tgtaaacgtt ttaactcctg aagaggcacc
      421 tcttggctgg gtcttaccta tgagttcttt gggagcatct gggatgtttg cggggatctt
      481 atctatgatt tttgcagtgg aagtatatcg tttctttaaa aatcgaaata ttactatcaa
      541 aatgccagaa caagtgccac ctgctgttgc ccgtagtttt gaggcattga ttccaggtgc
      601 agtcatttta acaattactt ggctgattcg aagcgtcgcg ggctttgatg taaacgctgc
      661 cttattatcg ttattcgagc ctttaaccaa tattttaggg aataatttgc ttggtgtttt
      721 actaccaatg tttttgatcc atttgttgtg gtcatttggt atccatggca tgagtattgt
      781 aggggctgtt gttcgtccaa tgtggctgat catgttggat gagaatgcaa aggcattggc
      841 agatggtaca gctgccaccc aattacccta tatcgctcct gaacagtttt atcaatggac
      901 ggtaacaatt ggtggtgcag gagcaacgat cgtggtatct gttttgttta tattcttctg
      961 taaatcaaaa ttcttgaaag aggttggtcg tttttctatt attcctggta tcttcaatat
     1021 caatgagccc ataatttttg gagctcctat gatgttgaat ccttacatgt tcatcccgtt
     1081 caacttagtt cctttagttt tgactattat cagttatttt gcagtcaaat tagaaatggt
     1141 caatagattt actgttttgc caacatggac attaccagct ccaatcggcg gttatctttc
     1201 agcaggaaat gactggcgtg ttgttatctt gatcatgatc aacacattga tagcatttat
     1261 tatctattat ccatttgtaa aagcttatga taaaaagatg ctgtcagatg aacaaagtcg
     1321 tggagaaaac gaagtccaga ctgtctaagt ttggttttta gaaggtggga aacaatgtat
     1381 tggctgattt tattttttgt ttttatcttt ttattaacgg ctagtcacct tatattgaat
     1441 atgctagcta catatcatat tcaaatcaat cgatggattt gggcactggc atcatttttg
     1501 atcgtgattc ttccaaagat cattgtaccg catatgaatg ttttgttttc atgggggaca
     1561 tatgtacttt gtggaatttt tgctatcaat tttatgatcg agcagcatag atggtttgtc
     1621 acatcgaagc tttaaatgtt ctaaaagtgg ttgtaacaga agtggttagc ttcaagaaat
     1681 aagaagaaat ttacgaaaat tgcttcttaa atttttgtga aatgttggct tatttttcgt
     1741 ttggttgaac ttattaccgc agatgcaagc ttttgaccac cgtttattcg gaatatggga
     1801 ctgtgacaag gcttttgtca cagccctttt ttacataaag attattattg ttttaactgt
     1861 tttggcagaa agaaggagga aaaaatggaa attttatcag caatggattt agaattagta
     1921 gatctactac caaagtgatc aagtcaaata tagatttggg agcttacaac catatagtag
     1981 gggctgcagt atggtgtatg aatggtaata tgtatgatgt gagtgtttat tcaaatcatg
     2041 aaacgtgtat agaaataatt gtgctgggaa tagcaatcag tcatggtgaa cgtgactttt
     2101 agtgtatcgt tgctgacgac atagaacatt ctgacatgat ctactcaata tgtggggatt
     2161 gctggcagtt tatataggag tatgcatcgg attgcgagat cattgtctca acagaagagg
     2221 gaggttgatt atcaaagata aagtggtaaa tcctacattt gatttagtaa ttgttgaggg
     2281 gactagcggc acaaatctct acaaagcgat gcttctagat ctatatgaca cattttaaga
     2341 aaatgtattt gcctaattat tatggtcttt cttttgaaga aacgttgaga tgatccaacc
     2401 agagaaaggt gtcaaagaat ttgactaaga ataaatggca gacgctacct atgctcattt
     2461 ggatagcgtc agatctttta ttttaaggat gattttgtgt tttttagaca ccgtaattta
     2521 agtaactcta acttttcaat ccactattta ctttttttgt attttcactg tctgggtctc
     2581 gaatagcgaa attactgatg agtctctatt aaaaaagctt tttctacttg aaactatatt
     2641 gggtggttgc tcaggaaggt ttcgatttct tgaattgctt gttgtggacc atttattgga
     2701 aaaacggctt gcagcgtgcg tgcctgctga cgaatcttgg gtgaagaaac ttcgcgcaga
     2761 gcaatctgca gttttctttc agtcactggt tttgtgaggg cgattgcgtt tccgtatttt
     2821 acacaatagt caatattaca gctttgctca aattgcatcc ccacaccgat aaacggtttg
     2881 ccggattcac aggcagtttg gacggtccct tccccgccgt ggataaaaga aaaatcaatg
     2941 aattcatgca aaagatgact agacagatat tctgttatta aaagatcttc tgagtcagat
     3001 tgaatgtcat caagcagata gtcaataggt gcaataaccg ctagatccgg ttgtttttgt
     3061 aagaagaaca aaattttgcg taacatacgc ggattgcctg aactacccat tgcgaaatag
     3121 ataatacgtt ttctttcttg ttgctttcgc tgtataaaag ttagcacttc ttcaggcaag
     3181 gaagtactga gcttagcaaa aattggacca acgattcgat aattttccgg cagctgttct
     3241 tcttccaaaa atagtttagg cgttgtgatg agatttagat cagcatccat catttgtaaa
     3301 cttgtttttg gtaaaggaag catttctttt tgtgcagcgt gtttgaaggc attggggatc
     3361 catcgggtat ttactatacg cttttttgtc cagtgccaaa ggggattgct taaagggccg
     3421 aagaaacgta actcgtgggg catcagcgca tgctctgatt gaaaaaaagg ttcactcaaa
     3481 gcatagggtt taacatatac taaaggaatc tttttattgc gggccgataa aaaaattgtc
     3541 acattcgaac ctgtcacaat cagtcgaggc tcaaacttag caatcagact ctgttcacta
     3601 gtgatacgag aggcaaccat ttctttggta aaagggtttt taagtgtacg caactggtca
     3661 aattttatga tttgttcttc ttgttttttc gtaaggatcg gcgctagtaa atgatactca
     3721 aagccacttt ctgtgatcaa aggagcaaaa gttttagaaa agccaaagaa tacacagtaa
     3781 taacggtctt tcatagcttt ggcaacctca atcattcgtg ttgtctcagc taaattgaat
     3841 actgcaggag caaaaagaat tgtcttcatg aaatcctcct tattggaatg agtctatccc
     3901 ttcgtttctt actagtatac taaaaaacac agcgttcgag tagcctatgt atattttgaa
     3961 tattaaactg tctctcgctg ttttcacaac ttctaaattt aaattttgta atcaagttga
     4021 aactccaatt ttcaaaaaaa cacgcaacaa ttttttgatc gatttatatg ttgtgccaga
     4081 taaatacgag aagttgtgtc attaaaaata aacatgagaa cataaaa
//
LOCUS       DAZAOD010000156         4098 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000156 DAZAOD010000000
VERSION     DAZAOD010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.159"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..275
                     /locus_tag="ACHDPO_002789"
     CDS             <1..275
                     /locus_tag="ACHDPO_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FosX/FosE/FosI family fosfomycin resistance
                     thiol transferase"
                     /protein_id="HFN3370349.1"
                     /translation="FLVKDLWIAVMQNSSNKLPKTYNHIAFKIDEQDIDSFVSKIQML
                     GLTVEPGRSRVKGEASSIYFYDYDNHLFELHTGTLQERLKSYNSTT"
     gene            complement(547..837)
                     /locus_tag="ACHDPO_002790"
     CDS             complement(547..837)
                     /locus_tag="ACHDPO_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370350.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1239..1475
                     /locus_tag="ACHDPO_002791"
     CDS             1239..1475
                     /locus_tag="ACHDPO_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370351.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1482..3434
                     /locus_tag="ACHDPO_002792"
     CDS             1482..3434
                     /locus_tag="ACHDPO_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFN3370352.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3506..4003)
                     /gene="dfrG"
                     /locus_tag="ACHDPO_002793"
     CDS             complement(3506..4003)
                     /gene="dfrG"
                     /locus_tag="ACHDPO_002793"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFN3370353.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1387 a          725 c          708 g         1278 t
ORIGIN      
        1 ttttcttagt taaggaccta tggattgcag taatgcagaa ttcgtcgaat aaactgccaa
       61 agacatacaa tcatattgct tttaaaattg acgaacaaga tatagattcg tttgtctcaa
      121 aaatccaaat gttaggttta actgtcgaac caggacgttc tcgtgtgaaa ggcgaggctt
      181 cttcaattta cttttacgac tatgataatc acctcttcga gttacatacc ggtactctcc
      241 aggaacgttt aaaatcctac aattccacta cctgagacta gtaatgacta gtctcttttt
      301 atggcctctg atccccccat tgagcgaata ctaatagggc ttcgaattga tctgttcaat
      361 ctttaagcaa tatccctcaa atgagtttgg aaagtttagt gattcatcac aaatacttaa
      421 atacatgtag ttatatatag attgaggttc ttgtgagcgt atgctcgtgt gggttcaaat
      481 cccatcgtct gcatccatct ttccaaaaca agcggctagg acatttttgt ctcagccgct
      541 tgttttctag tttattcttt catcttgtcg gacctttttt cttgggtata gacttttctc
      601 atattctacc acaattttgg gtttccctaa cacatgatag gatctcacaa caaattgctt
      661 tctattatta taataacctg taacgactaa cttcatccct tcgtctactt cagctaggaa
      721 gttcaaacta tgggaagcaa tcaaacaatt gaccccattt aaactgaaac ggatcaacgg
      781 tctggcacta acttgcaaag tacggatctt atctactgtt ccatattttt tctccataac
      841 cttcacctca ataccattat acgaacatac attccctttg taaagaagaa actctgtttt
      901 atctttttga ctttttgtct attacctttc ttaaaatcat attggcactt cctgcgaaga
      961 tgaaggacat gtactaaaaa aaagaggcag cagtatagat ttaagtagtt cagttttgga
     1021 gtacaaaaag tgaaaatgta aacctaaatg agtatcaaat tgcaactgaa tttgatactc
     1081 gttttttatt gttaaatcaa cgtttgttgt taatttacac cacaaaatgt aagttaaaat
     1141 gtatataaaa atgcgaacgt gaaataatta ttgtaggaat gcaaattggt gtgttaaaat
     1201 ggttacaatt tactaagcaa aaaggggtgc attttcctat gcaatttctt gagccaaaaa
     1261 ataagaacgc taagtctgtg gattgggaaa tatcagagca agtaagggtg atagttaagc
     1321 aatacgctga atatgcagag cgtactgaaa gcgaagcagt ggatgaattc ttattgaaca
     1381 ttttagacga taagaagttt attgaatgga ttgccaacaa gcgaagtaat aagcggattg
     1441 ttgaaaaaat gggtatcaaa gatagagtgg gttgatagac aatgaccaag cttaaaagat
     1501 tagccacgaa ggaagatgaa attgtagatg ttaaaattcc gatttcaaac gaagaattaa
     1561 aagatagggc taaacaatat gatttattaa ctccaaaacg atttgcaaca aggtataaca
     1621 aaatgttgtt cttgccaacg tcttttaaat ggaacggttc tgaatatccc attcaatata
     1681 attactgcat caatccgttt tgttgtaatt ttgggaaaga acagcacaaa ttcaaagatg
     1741 taaaagggaa accaagtcga tataaaatga ctggtagttc caaagataaa ggtcataaag
     1801 gtatgtactg caatgacaat cctattggca gaggtgtatc gcaaaactgt acagtaaccc
     1861 ctttatctaa ttggtctgtt gttgaagaaa ttaaacgcct tatagaaatc aatagcatcc
     1921 aagatgttga gccagattat caatttcata aagaaggctg ctcggaagaa gaatcaaccc
     1981 cattcaatga gccgaagcaa ttttacaaaa gggggaaaag taggggcaaa tctcaacgct
     2041 atcaatgtaa ggcgtgtaag aagttcacta atgttctacc aaaaagagaa gaaaccacta
     2101 cttatcacca acaaaagaac accattcttc caatgttcgc taagatggtt gttggaaggg
     2161 tttcagtcag tcgtacttgt gatattttag gaattggagt tggaacctac tatcataagc
     2221 tggagtggct gtataggcgt tgtttggagt ttttagaacg atatgagaca caaccccttc
     2281 aaacaaagaa atttaacgag atgtggctta atacggacaa gatgcactac tacctaaata
     2341 acgtccgtaa gaaaggacaa ggttcaaaga aatatacggg gtttgaagac cttaatatgc
     2401 aaacgtatat agttgtatct gctgaggtct tatcaagata tgtgttccgt tctgatgttg
     2461 cctatgattg gaatatttca atggatgaat taaatgaaga tacaagaaaa ttcaaagaag
     2521 accatctcaa tacttttagt cgtaaaaatg ataggttaga ttggtcttat tatccacaag
     2581 aaccatccgc taacgatagc gaaaatagga atgcttatct tcacgaatta gggaaaatta
     2641 ctaataggag tagatttgtc gatggtttaa atgttgatgc tccttatact acaactgctc
     2701 actattggtt aattaaacaa atggttaatg ccgacgaatg gcgaatgatt agtgatgatg
     2761 acttctctat tagaaacgcc ttttatagag tattcacgaa agaattaagg ttgagcgatg
     2821 cacatcattt tatttgccaa gttaacaaga cgaaaagcag aaaacaatgc ttaaaagaat
     2881 tcggacaagc aaaagcagaa ctgctcgatt ggggagatat cagaggattc aaaacaaagt
     2941 ttctacggac tttggcatct cattatctaa ctgaattact aacaagtcat caattccacg
     3001 aagaggctat tagtaaagat ggagaaagat atcgcaaata tgccgataac cctatcaaac
     3061 atccattagc cactaaggat aaaggatttt attcagttga ttgtagaacg gatttatctg
     3121 ctctggaacc aaacgaaatc gcaaagatgc tattaaatgt taatgaccat tcgaccaata
     3181 gctttattca acagataaga cgttatatat catctcttga aagaccatta acaacagctc
     3241 gtggtgataa gaagagctat atttacgcta acttcaatcc gaagtatgct caatttgcga
     3301 ttacaattct aagaacttac tacaactttt gtcgcccttt taaatcagcg gataaaaagg
     3361 ttttgacacc tgctcaaaga ttagggatta cagataaaca atttgattgg aaagatataa
     3421 tttatttcaa atgacaaaaa gagcttggag taatcccaag ctcttgtgct ttatctttac
     3481 tgttcttctt caattaacgc acccgttaac tcaataagtt ttttctttca tatacatgaa
     3541 aatagtagtt atacggattt ttatcattct ttatcccttt ttgggcaaat acctcattcc
     3601 attcctcata attcacttct ggaaaaaaag tatctccttc gaattcatga tgtatttttg
     3661 tgatgtacat tttctcaaca taagggaaaa acaaattata aatctgttct cctccgaaaa
     3721 taaaaatttc ttcttcgttt ttacataact caaaaacatc ttctattgaa tgaacaattt
     3781 cacaaccatt aaaggtaaac cccttatctc tcgtcagaat aatatttctt ctgtcaggta
     3841 aggctcttcc gattgattca aggttcttcc tacctaatat tatcggatgt ccctttgtag
     3901 tatttttaac atattcccag tccttgggaa tcctccaagg aatgtcattc tctttgccaa
     3961 tcactctatt cttatccatc gcagcaatca aagaaacttt catttataac acagcctttt
     4021 taactaattt accatctaat ttcttatttc tatcaaaaaa ccttttctca ttatcctgcc
     4081 cgttagttga ataagcaa
//
LOCUS       DAZAOD010000157         4027 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000157 DAZAOD010000000
VERSION     DAZAOD010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.160"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(137..1642)
                     /locus_tag="ACHDPO_002794"
     CDS             complement(137..1642)
                     /locus_tag="ACHDPO_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFN3370354.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1639..2325)
                     /locus_tag="ACHDPO_002795"
     CDS             complement(1639..2325)
                     /locus_tag="ACHDPO_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFN3370355.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2518..3939)
                     /gene="gndA"
                     /locus_tag="ACHDPO_002796"
     CDS             complement(2518..3939)
                     /gene="gndA"
                     /locus_tag="ACHDPO_002796"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFN3370356.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1107 a          853 c          691 g         1376 t
ORIGIN      
        1 acatttaatt aacggatgtt attctattta attgttcgct agttttttta taatgacatc
       61 cctgaatttc tcacttgctt gtattttgta ccttattctt tgttggatat ataaaaaaac
      121 aagtaaagca catgctttac ttgtcttctg cctttgcgat aggaataaag attctaaaaa
      181 ttgtcccttg ccctactaca ctttctgcta agatacgtcc tttatagttt tcaaccagtt
      241 gtttagcgat agacaacccc agaccatttc cacccttcgt tctagctctt gctttatcca
      301 ctcgataaaa acgattgaag atcttattaa ggtcttcttt gggtattcct tcgccaaagt
      361 cctgaatcgc gatctcaaat tcattcagag tggaagaaat agagatatgg acttcttttc
      421 gtgtagttga atactttact gcgttatcca atatgataat gattaattgt tcaaagtgat
      481 tacgataaat ttgcagggtc acttcttttg tcaaatcatc atctaaagtg atcacatagt
      541 ctggatataa tatcttgaaa ttattataaa cttgataggt gacttctttt cctttagttg
      601 tttcattcgc ataatgaaca tctacttgtt ctgctcttga taagtctagc atctcttgaa
      661 ctaagctttt catacggctg atttcttgca tgctggcgct taatgattct tctaatatct
      721 caggatcatc tttcccccaa cgatttagca gactaagatg cccttcaata attgcaacag
      781 gtgtccttaa ctcatgagat acgtcttcca cgaattgctc ttgttgttca atatacaaac
      841 gcatacggtc aagcatctca ttgaatattt cagctaaatc tgccaattca tcatttgtgt
      901 cgatttcagg catgtggata tctgattgcg gatctttacg tatagtatcc attgtatctc
      961 tgagtacctt gagtggtttt aagaaataag aagataaaaa gaaacctaaa atactactta
     1021 agatcaaaga aacaacttct aaaacaataa gagtcaataa tagcttattt cgaatatcat
     1081 agaaagaaga taattcatag aagctttgcg catagccgat cttttctctt gtacctttag
     1141 aatatatagg ctggatagat aaaaagccag tttttccttc tagtgtaacg atcgttggaa
     1201 ctttacgtgt agtctgaatc aggtttcgac tgttttcatg ggttttaaaa atcaagttct
     1261 cgtccaaatc ataaacataa agatccattg atggctgccc tagctcagct ataaagggat
     1321 cgatcttcat taagtttcct tcgaccagtg aagtatgatc tacgacctca tctccgtcat
     1381 ttgtcgcttt cgtcagatta cgatacgtat ttactaatgt cagttcttca tccgagttag
     1441 ccaaacgaga agctacttct gaaatcgtac gctctacatt gtttctttct tttgccacaa
     1501 tcagattgat agatgattta taggtaatga cagcgaaaat tgtaaacaca acgaatatga
     1561 agaaagaact cgcaaaggcc cacttgattg tcaaggaggg ccctttcagt tctctttttt
     1621 ccgatttttt cggctttatc acgagcgcat cacataacct gttccgcgta cagtttggat
     1681 atagctttcc tccccgggaa cgtcaatttt gttgcgaaga taacgaatat atacgtccac
     1741 tacgtttgtt tcaacttctg tttcgtatcc ccacacttta tttagtaaaa cgtcacgtgc
     1801 taataccacg ttcacgtttt ccattaaagt aagcagcaac tcgtattctc tttttgttag
     1861 ttcaattact tcatttccgc gacgtacgac acggttttct ttttcgatag tcaaatcgcg
     1921 ataagtaata gtagtttgtt tagccacatt tttatcgcct tcaatatcga ttcgacgcaa
     1981 caatgcacga agacgtgcta ataattcttc gatagcaaat ggtttgacga tgtagtcatc
     2041 tgctccgtgg tcaagtccag atacacgatc gatcacagaa tctcttgcag tcatcataat
     2101 gattggtgta tttttgactt ggcgtacacg tctgcagact tctaaaccgt tcaattctgg
     2161 gagcatcaga tccaacaata tggcatccca ctcattattt aatgccgcat ctaaaccagt
     2221 tcggccgttg tagtggactt ctgcgttata cccttcatgc ttcaactcta gctcgacaaa
     2281 tcgtgccaag ttcttttcat cttcaatgat tagaatattg ctcatttatt attttatcct
     2341 ttctattcta ctggcttttt aaaaactcta tcattatacc gataatatgc ttaaaaatct
     2401 atagtcattt tatcatggat agcaatttta aaaaagagct gaagtctact cataacaatc
     2461 gacttcagct ctttcgtcct ctttttattt tctcatttcc taacagccga aagactatta
     2521 ttcttcatgg taccatgagt aatggaagat tccttctttg tcgacacgct cataggtatg
     2581 tgcgccaaag taatcgcgtt gggcttggat tatatttgca ggcagacgtt ctgctctgta
     2641 tgaatcgaag taagcgatgg ctgatgagaa agtcggtaca ggtacgccag cttggacagc
     2701 caaggcaacg acgtctctga ctgattgctg atattttttc gtgatttcaa cgaagtaatc
     2761 atctagcaat aaattttcga tctcaggatt tttgtcatag gcatccgtaa ttttttgcaa
     2821 gaatcgagct cggatgatac atccagcgcg ccagattttt gcgatttcac caaatggcaa
     2881 gtcccaatca aattcttttg aagcgacacg taattgagca aatccttggg cataactcat
     2941 gattttactg aaatacaacg cttctcggat tttttcgacc aattcttttt tgtctcccgt
     3001 gaactcaaaa tcgttcgtac gagacaaaat cttgcttgct tgtacgcgtt cttctttata
     3061 agcagaaata tagcgggcaa atacagattc agtgatcaat ggaagtggca cacctaagtc
     3121 aagcgcgctt tggcttgtcc atttacctgt tcctttattc ccagctgcat caaggatcac
     3181 atctactact ggtttacctg ttccttcatc gtctttacgt gtcagaatgt cagcagtgat
     3241 ttctatcaaa tagctgtcta attcgccttg attccattct ttaaagatat cagccatttc
     3301 ttctactgaa aggtttaaaa tattcttcat taagtcataa gattcagcaa tcagttgcat
     3361 atctccatac tcaataccgt tgtgtaccat tttcacataa tgtccggctc catttgggcc
     3421 aatatatgtg acacatggtg ctccgtcttc tgcttttgca gaaatttgct ctaagattgg
     3481 tgcaactagc gcataggctt ctttttgtcc accaggcatg attgaaggtc cttttaaagc
     3541 tccttcttca ccaccggaaa cgcctgtacc gataaagttg atgccagagt tggctaactc
     3601 ttcattacga cgcatcgtat ctttaaagaa tgtatttcct ccgtcaatca aaatatcgcc
     3661 tttatcaagg tgaggaagta actcttggat tgttgcatct gttgccggtc ctgctttgac
     3721 cattagcaag atccgacgtg gtttctcgat agattctaca aattcttcga ttgtatatgt
     3781 tgctttgaaa tttttatctg ggtgttcttc tactacagcg gttgttttag cccctgtacg
     3841 attgaataaa gccactgaat agccgcggct ttctatgttc aaggctagat ttttacccat
     3901 aacggccata ccgacaacgc cgatttgttg ttttgacata tgaactcctc ctacatacgg
     3961 gatttctccc taatctctta cattatagct taacacggct acattgcaaa ctaaagaaca
     4021 acatatt
//
LOCUS       DAZAOD010000158         4019 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000158 DAZAOD010000000
VERSION     DAZAOD010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.161"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(225..458)
                     /locus_tag="ACHDPO_002797"
     CDS             complement(225..458)
                     /locus_tag="ACHDPO_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFN3370357.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(473..1423)
                     /locus_tag="ACHDPO_002798"
     CDS             complement(473..1423)
                     /locus_tag="ACHDPO_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFN3370358.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(1420..2262)
                     /locus_tag="ACHDPO_002799"
     CDS             complement(1420..2262)
                     /locus_tag="ACHDPO_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFN3370359.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(2264..2983)
                     /locus_tag="ACHDPO_002800"
     CDS             complement(2264..2983)
                     /locus_tag="ACHDPO_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFN3370360.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            3531..3833
                     /locus_tag="ACHDPO_002801"
     CDS             3531..3833
                     /locus_tag="ACHDPO_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370361.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            3905..>4019
                     /locus_tag="ACHDPO_002802"
     CDS             3905..>4019
                     /locus_tag="ACHDPO_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HFN3370362.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNR"
BASE COUNT         1378 a          719 c          512 g         1410 t
ORIGIN      
        1 aacgtttatt actgaactca ttccttagag ctaaactaat gagaaagagc agaataactg
       61 atacaaaaag caatcctaca agaattaata gactcatcta aatcattcac cttttctaaa
      121 ataatccgag aaagatttaa aaaaattata tccagctatt aggataagtc ctatcataat
      181 cactccaata gccattttct tatcctccct aaaaataaag tcttttactt aaaacctttt
      241 ttgtaatcgt caataaattt tttcccttta tcagttaatt gaaatcctat atctaaatag
      301 tcctcatatc taagtttagc cagcatctca cttacagatg ctggactaac acttagaact
      361 tttgctaaat cattattttt taatttcttt tttctttttg ataattcctg aattgctagt
      421 aaataaatta gtatagtagt cgttttaatt tgtaccatac ctaccctcca aattatttcg
      481 aaaggccttc agcaatttta tccaggttcc atttcatcat cgcatagtaa ctatcaccat
      541 cttgtccttt ttctgcaatt gaatcagtaa aaatcgttga atagatagga atattggtat
      601 cttttgatac tgttttcatt ggtctatcat ccacactgct ttctacgaat aaggagggaa
      661 cttttgttgt gcgtaatttt tcaactaagt gttttatttg atctggtgtt ccttcttctt
      721 cagtgttgat ttcccaaatg taagcagaag gcacattata cgctttcgag aaatatttaa
      781 agcatccttc acttgtaaca atcatttttt tatcattcgg aattgaagca aatttagatt
      841 tagcttcttt gtctagagaa tccaattttt caatatactt atctagattt tctttataga
      901 attttttatt atcaggatct ttttccgcta actgtttttc aatattttta gcgtaaataa
      961 taccgttttc taaatttaac caagcatgag gatcttcctt ccctttctca ctctgaccct
     1021 ctaagtaaat aacatctatg ccatcacttg ctgcaaaata gtctttgttt tcctctttgt
     1081 tcgcattttt aactaatttt gtaaaccaag catttcctcc agtttccaag ttaacaccgt
     1141 tataaaaaat caaatctgct tttgaagttt tttgaacatc ttcaggcaaa ggttcatatt
     1201 cgtggggatc tttcccaata ggtacgatac tgtgtaaatc aattttatct tttgctatat
     1261 tttcggtaat atctgctaaa atcgaattag taactactac ttttaatttt tcgttcgaag
     1321 ccactttatc tttgtcttta ctatttattg aacatgcccc gaatataaaa agagcaatca
     1381 aaatccccag acttcccagt actgctttcc attttctcat cataacgatc tctccttctt
     1441 tcttaaaaat ttttgttttg gtgagattag aaaactaatt acaaataaga atgccgctgt
     1501 taaaacaata cttgatcctg ctgctatgtt aaaactataa ccaataaaca atccaagcaa
     1561 tgatgaactt gctccgactg ttgcagaaat aaatatcata gttttcaagc tatttgcata
     1621 taaatatgct gtagctgctg gtgtaattaa cattgcaaca attaatatag ttcccacact
     1681 ttgcatagct gttactgcta ctaaagttaa tagaaccatc aatagataat gataaaaact
     1741 gacattcatc cctattgctt ttgccattaa tggatcaaaa gaagtgatta ataattcttt
     1801 aaaaaataga actactataa ccaacactaa aaccgaaacg ccaattgtaa tccacttatc
     1861 aatatcttgt acagctaaaa tatttccaaa taaaatatga aataaatccg ttgagctatt
     1921 tgcaactcct ataaggataa ctcctagtgc taaaaaagaa ctgaaagtaa taccaattgc
     1981 tgtatctcct tttattacac tattgctttt tataaaagta ataatgatag aagctaatag
     2041 accaaataca atcgcaccaa taaaaaaatt aatacctaaa atataagaaa ttgctactcc
     2101 tggcaaaaca gcatgagaaa tagcatcacc cataagagac attcctctta aaataataaa
     2161 acaacctact gttccagaaa caatccctat aactacagat gtaattagag cattctgtaa
     2221 aaagtgaaag tcatacagac cattaataaa attttgaagc atattattcc ccctctccaa
     2281 taaatatagt atctccatag gcttttttta aattttcttc attaaataca gattctacac
     2341 ttccgtgagc aattagattt cgattcaaaa gaataatatt atcaaaatac ttctttacct
     2401 tgcttaaatc atgatgcaca attagcactg tttttccctg atgtttcaat ttttttaacg
     2461 tatccataat tattcgttca ctaactaagt ctatccctac aaatggttca tctaaaaata
     2521 tgaaatccgc attttgagca agacatcttg ctaaaagtac acgttgaaat tgtcctccag
     2581 ataattctcc tatttgatga ttagaatatt ttcccatatc gaccttttcc aaagcctttg
     2641 aaactctttg ccattctgca tttttaattc tttgaaaaac tttcattccg gcatatgttc
     2701 ccatagatac acattctttt acttttattg gaaaagtaaa atcaatatca gctttttgct
     2761 ctacatatgc aatcttcacc agttttttat tgatatcttc attattaatg gagacctctc
     2821 cctgatgagg gataatattt aacattgctt taagcaatgt ggattttcca gcaccatttg
     2881 gaccaataat acctgttaaa gcaccttctt gtatttttaa agaaatctcg ttcaatgcta
     2941 aaaaatcgtt ataacaaaca ttaagctttt tcacttctaa cataactttc tccttctaaa
     3001 tgataatgat tatcacgatc atatggtata caaaaattat attttagtca accctaaatt
     3061 ttatagttta gatttttttc tgttgctgaa gattagaatg acaaaactat ttgaaactac
     3121 gcgtatagta agtagctttc aaaatatata aaaaaggagc gttctcaaat gagaacatgc
     3181 tcctaaaact actttattgg cgtatggaaa aattatactt gaagtggata gcgggttgaa
     3241 taagttgata agcatcaaaa catttataaa aattattcaa gactatgtct gttccatata
     3301 caaatatgaa aatcagtaaa ctccatttaa cttttttcgt agtgtgtctt tttatacatg
     3361 tttatcgtta ttaatagtga ataggaaaaa aactattttt gatcattgac aattaaatac
     3421 aatttttgaa taacgatccc tgctattcga gctagaaact caagtacgcc atgacctgat
     3481 tagcgacaaa tacttagaga tttctttttg ttctgggaaa acaaaatgcc atgacaatag
     3541 cagcaaataa tgatacttcc gtaaggctcg ccgtaaactg gggagaggtg aaattcctat
     3601 gtgcttaccc aaagcaattc aaaaatttca taactactat tttaggagat gattttatag
     3661 aatccagagt ctacctgaat aaaaaacaaa cctgtgcatt tctaggaatc gataataata
     3721 ctctagataa gtggattcgt atatataatt tcccagtaat aagagttggt ggtgtagttc
     3781 gctttgacgt agaagatatt aaagacttta tgaatacatt taaaataact tgaaattttc
     3841 ttctcgccgc atatactaaa attagtgaaa tatactgcct tacttttttt aaggagtgag
     3901 gattttgcct acaaagcttt caaatgggaa atataaaact aatctgagat atccaaaaag
     3961 gtttaaagaa ataacaggaa ttgcatcaga aaagtatcaa aaaacatttc caaataggc
//
LOCUS       DAZAOD010000159         3994 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000159 DAZAOD010000000
VERSION     DAZAOD010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.162"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            72..155
                     /locus_tag="ACHDPO_002803"
     CDS             72..155
                     /locus_tag="ACHDPO_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFN3370363.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            280..1017
                     /gene="erm(B)"
                     /locus_tag="ACHDPO_002804"
     CDS             280..1017
                     /gene="erm(B)"
                     /locus_tag="ACHDPO_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFN3370364.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1280..2143)
                     /locus_tag="ACHDPO_002805"
     CDS             complement(1280..2143)
                     /locus_tag="ACHDPO_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFN3370365.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2145..2417)
                     /locus_tag="ACHDPO_002806"
     CDS             complement(2145..2417)
                     /locus_tag="ACHDPO_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFN3370366.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2434..2643)
                     /locus_tag="ACHDPO_002807"
     CDS             complement(2434..2643)
                     /locus_tag="ACHDPO_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFN3370367.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2721..3617)
                     /locus_tag="ACHDPO_002808"
     CDS             complement(2721..3617)
                     /locus_tag="ACHDPO_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3370368.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
     gene            complement(3773..>3994)
                     /locus_tag="ACHDPO_002809"
     CDS             complement(3773..>3994)
                     /locus_tag="ACHDPO_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HFN3370369.1"
                     /translation="TEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIR
                     GLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         1219 a          701 c          630 g         1444 t
ORIGIN      
        1 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
       61 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct accgttttga
      121 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
      181 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      241 gtatttattt atagatgtaa tcacttcagg agtgattaca tgaacaaaaa tataaaatat
      301 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      361 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      421 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      481 tcagaaaaat taaaactgaa cactcgtgtc actttaattc accaagatat tctacagttt
      541 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      601 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      661 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      721 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      781 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      841 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      901 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      961 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
     1021 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
     1081 attaggtata gggcacctct aataactacc aattaattca cctcaaaatg aaattagaaa
     1141 aaaacagcga aatttttaaa tctatttctt atcgatacaa attcctcgta ggcgctcggg
     1201 accccaacat gaggaaatgt ttttataaaa aaagagtagt taccgttttt tggtaactac
     1261 tcttttcctt ttttaaggtt taaatacctg gaagtttagg tgttttgggt attggtggtg
     1321 taggtagctg caagctttcc attttttgtt gaattgcttt aaattcaggg gtttcttggt
     1381 gttgattttg aaccattttt tgctctattc tctccaaagt cggttgaatt tctttccctg
     1441 atactttacg atttaattct ctttctaagg tctctttcgg actaatggaa ggcgtttcta
     1501 agcttgaata gagtttcact ccttctctat tgtaaagcct tatatcgcta aataagcccg
     1561 ttttatgaag ggtttctaaa ttggtcggta agtttttgac aacaatatca tgcgcttgtt
     1621 ttggtgttgc cctagctgtc attggatcat ctgcatacat ggtttcatat cgttcaatcg
     1681 ttcctaagta tgattcaatt ttcggtactg ccatgacgta tatttttgtt tcataacctt
     1741 tagattgaag cattgtggct gtttgaatgg gaacgtctgt tgttcgtcct gttccttcaa
     1801 tcactaaatt atagccttga tcgcttaaac ggctaataag tgcttctgtc atgcgattcg
     1861 aataaggggt aacgtgtttt actacgtctt tttcatagag tttcactaat tcgtcaaaat
     1921 ttgggtgctg ttgtttaaag gtatcattat caatgacaat aacattccct tgtgtttctt
     1981 caaaaattgc tgatcgcaaa ctggttttcc ctgaccctgg ttgcccacca agtaaaaaag
     2041 cggttggcga ttcaaccgct agtctatttt tagttagtcg ttcaacattc ttttctaaac
     2101 gatcttcaaa ttgcttttcg gtgaagtcag taatattcgc catgttaagc cactttctct
     2161 ttattcaaaa tttgttttga atattgattc attgaccgcc aatactcatg aatagcttgt
     2221 aattcttcaa atggttgttg aaataaatca acttcttgtg ccacttctaa ttgatttaaa
     2281 agattcactt ctagtaaacg agtattttta gtatctagtt catgattcaa aacataattt
     2341 aatacccgat tataaacact tgccgataac tcattaatga tttcaatttc aaatgttttt
     2401 tcatacgtaa ctgccatttc attttcactc cttttaaagt ttgtcaggta aatatttccg
     2461 tatatattct tctaaggctt gatccataac ttcttttacg tttccgccat tctttgctgt
     2521 ttcgattttt atgatatggt gcaagtcggc acgaacacga accgtcttat cccccattat
     2581 atcttttttt gcgctgattg gcgtatcatt tcgttttgct ttctgtgcgc ctaaatttcc
     2641 cacgatcgct cacttctttc tatttcttct tactatttat tttatcatca cctatcacaa
     2701 atcacaagtg atttgtgatt ctattctttt tcattttcta attgaatgat tcgctcaatc
     2761 atttcaaaaa atacgttctc atacatagac aaaacttttt tgtcatagcc tttgtgttct
     2821 gtaatgccat ttttagacca agtacttact ttattacttc gcttgataat atttcggaaa
     2881 accaaattat cctctttatg ttctttgtac agttcttcca ggtttgattt tatcgttgcg
     2941 ctgtccgtat caactaaata aggaacaaaa ccaatcatat ctagtccagg gttaaactgt
     3001 tcttgcaaat caatcaaata ggaaatatag ttttgaatgt tgtttgtact ttcttcttct
     3061 gcttgtaaag ggatcataac gtaatcactc gccacgattg cattatttgt ataaacgctt
     3121 ggcgttggta cagtatcaat aataataaga tcatagtcac tttttaaagg tgctaaaaga
     3181 gtagcaagca atctactttc attttcaaac gtccatgagc gagttaattt tggcagtaac
     3241 atcaaatcaa acgtgccagg gatcaagtct aaattatcag tcaaatgaat aatagaagaa
     3301 gccaagtttc catttttcaa gccttcataa aaattgacac gtggcaattc tacctcaaaa
     3361 gtttttgcta agtcttttgt caatgttgcc tgtaagtcct tatcgatcat taaaactttt
     3421 aaattcaatt tgtctgtcaa gtaagcaaac atagtcgata atttggactt tccaacacca
     3481 cctttaaagt aattattcaa gataataatt gcttcatttt tattgtttaa aatacgtctt
     3541 aattcttcaa gtatttttag tttttccttc tccataacta cgccccattc tttttttgta
     3601 tagtaatatt gtatcattaa gaatcacaaa tcacaagtga tttgtgatta atcacttgtg
     3661 atttgtgata agtgatttgt gattaatata taaaagccct ctttaaaggg cttttatagg
     3721 ttctgttgca aagttttaaa taaagaataa aatcccttac ggtatctatg atttaagctg
     3781 ggattcccaa taataccttg atttcagtac agaccgaaaa cccgaagaga gtgccttctt
     3841 ttcgggtttt cttatataat cctcgaatgg cttccatgcc tttaatcgtg gtagaggcag
     3901 tgcgtaaact tcgatagaat ttattgcgtc tctttactgg acgatggtct tgttcaatca
     3961 aattattcag gtatttaatg gtacgatgtt ctgt
//
LOCUS       DAZAOD010000160         3897 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000160 DAZAOD010000000
VERSION     DAZAOD010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.163"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(718..3867)
                     /locus_tag="ACHDPO_002810"
     CDS             complement(718..3867)
                     /locus_tag="ACHDPO_002810"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HFN3370370.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1082 a          808 c          638 g         1369 t
ORIGIN      
        1 ggactaatac aggtagtcct cttttttgtt attttgatat tctaaatcat tttttattgg
       61 attattccct tgttcgatat agacccaaat tgatctatca ataattatca aactgagtca
      121 tatagagaca aaaatttcaa aaatgacctg ttaaatggtc atcgaatatc atttaaaatc
      181 aatacgacgg agtcagacac ggagtcaaaa caagcccgct gagagtaaaa aatatataca
      241 gtcccatagg taaagtgcca caggactgta tattttttta tttgagatta cctgaaatga
      301 ttccatttac tttttatctc attttttcct actagttagt atcaaatact ctcctatttt
      361 ctcaataaac tattttgggt tacatggtat ctgaaacagc taaaaccttg tcattacagc
      421 aaaaaatcac tttatctccg tttcatttca gatacatttc acttaagcgg attccaaaaa
      481 aacaaaagaa aaaggaaccc ctagttagcc tatgcttttt attggttcct ctcaaaacac
      541 ggtcatataa caacggggtg gggtaaatga atgaaaaagg tggaggaaac attattcaat
      601 agctgtctta aatacttcgt tataaaatgt gaacaaataa aagacatcta tccctatttt
      661 ctacacttcc actttactac catctttgaa tcgtacaatt ttcttaactc ttctcgttta
      721 cctcaattca ttttcaagtg gaatcagctc atcatctaac attttacgcc atgctcgctt
      781 catttcttgt gggtatttaa atggcttcgc ttctggatgg ttggctttat atccttcgta
      841 atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg gcatatattg
      901 cagattagaa gcatgtaatt ctttctcaga aacaaaccac tcattggaaa agacatgaat
      961 caaatcatca ctcgcttgtg taaaatagcg acgtttaatg acaaagatat cttcattact
     1021 atctaaagtc cccacatcaa acgcatttaa aatttgtcgg taaacttctt tgactccttc
     1081 tgttttattc aatttagcca aagctttttc aatttcttct cgtgcatctg aactattcgc
     1141 cgcataagtt cctagtaatt gatcaatata agtagaatca atatcataca acttcgtggt
     1201 attttcacta taaaattcga tcgtggaaaa atcttctccc tctttttctg gttcttcctc
     1261 tattaatgaa cccttcacgg tctcgtacac gccaatttgt tcttccaaaa gttgaatttg
     1321 attgttcaag gttgaagatt tcaccatgtc atcattgtaa tcgtcataag tcactaacga
     1381 ttcataagca cgattcaatt cttggaatgc tttgacgtac tcgatacgga tttcaagtgg
     1441 cgtatgttca tcaatggatt ccatggatga aacctctttt aacttaccat atgcttgctt
     1501 gaatcttttt ttggattcct gataacttgg ataaatcaaa cccgattctt cttttgcttc
     1561 tgaatacagt tttgtcgcat cctcgacatt cttctccatt gtggctggct ttcggaaagt
     1621 aacaattagt ccttttgttt tttctggata cgtacggttc gtacgtgaaa aagcttggat
     1681 caatcctgca tactctagat tacgatccac aaatagggtt tgaatcgtag gtgcgtcaaa
     1741 acctgtcaat agacgatcca ctacgatcac taaatcaatt tgtttcccaa attgtttgaa
     1801 ttccgctctt tttcgtgcca aacgattatt gatgtctccg ttataacgct caatgtctgc
     1861 taatgaccag gaagtatcat aatactgatt atattcctca ataatttttt gcatttcttc
     1921 ttgttggaca cttgaatctc ggctgttttc ttctaatgaa taggtaatag cgattcgtgg
     1981 aaaatcagga tcctccatcg ttcttccttc acgaatgggc tgattaggaa actcttttgt
     2041 taaccagtca ggttctttcg tcatttcttt gatcgctcga taatactttt tggccatgtc
     2101 aatggaactc gtggttaaga tcgcagactt cgttggacgg ccatttcgaa aatcaaattt
     2161 tgtataggca ttgtctggac ggaacatttt atgaatgact ttttggatat gttcatctgc
     2221 ttcaaaaaca gtagggtcca aataactttc ttttttgaca ggctccattt gatcaatcat
     2281 acgattgatc tgttccggtg aatactctgc atatgtttct acttctttta atttccgata
     2341 gattttattc tctaatgaag tcggctccac ggtgttttca tgctctactt gaaatcctaa
     2401 aaccgagcca tcttctaatg cattcttgat ggtataggta tgcaagacct ctccatactg
     2461 atcatgggtc gtacgtgcca attgcccttt ggcttgtttc cgattctcag ggaaaatcgg
     2521 tgtacctgta aagccaaacc aagtggattt cggaaacatt tttttgattt cttccatatt
     2581 ttcagcactt aacgctcgat gacactcatc tactacaaac acgatatgtt gccccattaa
     2641 tttttggaag cgattggttc cttttttctc ttcttgtttt tttgcatatt tcaacgccgc
     2701 atctagcttt tgacgggttg taataatcac aacatttgca ttggcatctg ccaacagagt
     2761 ttcacttaac tctttggcac ttcctgttcc cacgatcaag ctattcgctt tggcgttccc
     2821 ggaagaaatc ccagtattaa attccgaagc aaatttcgta aactctgtgg tggtttgatt
     2881 atctaaatct ttgcggtcca ctaacatgat cgtccgatcg atccccgatt ttcgtgctaa
     2941 aagcttagta gatacaaaac tagtcaacgt ttttcctgaa ccagtcgcat gccacacata
     3001 tcctgattga tgtttatttg cagcaataaa caaggcttga atcgcatgta cttgataagg
     3061 atgtaacacc atgaggattt tattgtcttg atcttcactg acaatcgtat aatccgcaat
     3121 caagcgatga gcatccggga tatttagcac ttgtttgcaa aactcatata agttttctac
     3181 ctttttatta tctttcgttc gccaactaaa taaaaactta ggatgcaaat cctttggtaa
     3241 ggcatttgca aaataccgag tggtttgttc attggaaacc acaaacaact gtaaggtcga
     3301 aaagatattg ttccgaaaca taccttcttc tgcatatttt ttgatttggt taaacgcctg
     3361 ataaaaacta tcttttgcgg ttacttgttt cagctcgatt tggacaatcg gtaatccatt
     3421 gatcagtaag gtgacgtcaa aacgtcgatc ccgtgcttct atgttacttc cacgttttgc
     3481 aatttgatgg accacttcat aggtagagat tcctccacca atgtcttgat tagaataaag
     3541 aatgagcgag acagaaccca gttgcggatc ttcccgttca atcgtgatcc gagccattcc
     3601 attttcacct tttaaccatt tcgcagcatc aaagggggtt ttcgttcgta gtaacaattc
     3661 tgttttgatc gtttcaaatt ctttatcggt caaaggaaaa tcattcagtt ctgcttgatt
     3721 atttgagatg attttttggc gtaaattgac ccaaagatct tcttctgatt ttagatcggg
     3781 acgatacgtc cactgattat gcccttcccc caatacacgg atcaactgtt cttcgacttc
     3841 cgcttcctca cggtgactaa ttttcattta tcttccctcc ctcgtaaaat atcattt
//
LOCUS       DAZAOD010000161         3757 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000161 DAZAOD010000000
VERSION     DAZAOD010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3757
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.165"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="ACHDPO_002811"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="ACHDPO_002811"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFN3370371.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="ACHDPO_002812"
     CDS             complement(1174..1869)
                     /locus_tag="ACHDPO_002812"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFN3370372.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="ACHDPO_002813"
     CDS             complement(1882..2598)
                     /locus_tag="ACHDPO_002813"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFN3370373.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3536
                     /locus_tag="ACHDPO_002814"
     CDS             2928..3536
                     /locus_tag="ACHDPO_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFN3370374.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
BASE COUNT         1075 a          769 c          666 g         1247 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcaaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aagaaagcac aggtgaaggt ggcgaaccag aagtgatcgg ttcaacagaa gaataatact
     3541 gaaacaatca ggtggtgtta gaagcggcgg gtcagcagct tttaacacgc cttttttatt
     3601 tctaatcgtt tattttcata tggggcttcc acttttgtaa atggctttac aaacgaaaaa
     3661 tcctaattta ccaagctttt cctcgcatac ttttatcgta cctttataaa aatttatact
     3721 ttgaaaaaaa gtattcaatt attgttgcat ttttcct
//
LOCUS       DAZAOD010000162         3710 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000162 DAZAOD010000000
VERSION     DAZAOD010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.166"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..353)
                     /locus_tag="ACHDPO_002815"
     CDS             complement(<1..353)
                     /locus_tag="ACHDPO_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370375.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRT"
     gene            complement(613..1161)
                     /locus_tag="ACHDPO_002816"
     CDS             complement(613..1161)
                     /locus_tag="ACHDPO_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370376.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1162..2019)
                     /locus_tag="ACHDPO_002817"
     CDS             complement(1162..2019)
                     /locus_tag="ACHDPO_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFN3370377.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2305..2591)
                     /locus_tag="ACHDPO_002818"
                     /pseudo
     CDS             complement(2305..2591)
                     /locus_tag="ACHDPO_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2581..2910)
                     /locus_tag="ACHDPO_002819"
     CDS             complement(2581..2910)
                     /locus_tag="ACHDPO_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFN3370378.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2987..3259)
                     /locus_tag="ACHDPO_002820"
     CDS             complement(2987..3259)
                     /locus_tag="ACHDPO_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFN3370379.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3259..3522)
                     /locus_tag="ACHDPO_002821"
     CDS             complement(3259..3522)
                     /locus_tag="ACHDPO_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFN3370380.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1087 a          752 c          472 g         1399 t
ORIGIN      
        1 aatgttctta ctgcctcttc cacactaatt tcttcgttca atttcactaa taatacttga
       61 tctcgcttat tataatcgct ttcatttatc ctaagagtca aatctttttc caccataact
      121 tttacaccca ataaattttg cggtttattt ttctctgttg aaattctttg tgtagccttt
      181 aaactgacaa ttagctcatt gggtacatac tctatttgag agtcatctaa ttggctcata
      241 atcctttctt tttggttagt atctgcagtt acttgtttag tatgagccat gaacccaaac
      301 atactcaccc caacaaccaa tcctaaatat attttctttt taaacttttt catctacatc
      361 tcctcctaat agttttattt tagagttagc tctattactt atttactaac tcaacaacag
      421 attatcatac acttgttaat gaaatcacaa tatctcatta aaacacaccc taaaatcata
      481 accgttccta tgctcatttt ttggattttt taatcacgta accagaaaaa taaatcccct
      541 ctatttcacg caaatcaaag aagaactaag taactaccgt ttaaaggtag ttacttagtt
      601 cttctttgat tattatctaa ctttattatt cattccccac cctttgcgca gtgagtcttc
      661 ggtatcttgt tttatctgac tggtagttct tattatttct ccacgatcat ctaattctgg
      721 aacaattgga tatttttctc tgaacaagtc tagttctttc accacgtcat taaacaaatc
      781 ttgcttatct tcttgcgtaa gattctgttt aatatactca tctaaagctt ttctaagcaa
      841 ttcatctctt gtcatattag tctcatactt ttctactaaa actctggaag tcgcatttaa
      901 caaagtcgac agttttaaag gatgcttggt ggaataaacc ttatcaaact ttctgattgg
      961 tgcgccaact ttttttgttc ttcctctact ctgtctttca acattggagg aagtttttat
     1021 ttcttgaact tggtgcactt ctaattgctt attttcagat ggtgtaattg cttgctgctt
     1081 tttctttgct tctgcttctt tttttatttt ggcgagtcct ttgttgttcc caaaaatatc
     1141 aagtcctttg atgtcagcca attactccac ctccgcatac caattctcgt gttcttccaa
     1201 ttctttcaaa atactgataa ataattcgtg gcttttgcga tcccattgtt ttaagagacc
     1261 tttctttgtc ttctccatcg taatacctga tccgtcgtat cgttttaagc gcgcattttt
     1321 gagtacaaca tttttaatca aatgttcccc ataaatctct tgggcttgtt tatacatttc
     1381 ctgatctact gcgtcaccgc tttccaacat gaaaggaata acaccagcaa catataaatt
     1441 tgtatcaaat tctttcacaa aaaagtccat atactcaaga tattgcatcg catttctcat
     1501 cgattttact tgggtctgta agacgacgat tgcccaatcc gcaatgtaca tcgcggattt
     1561 actatataca gaaatagaag gtgggacatc taaatagatg acgtcaaact catcaaataa
     1621 tggttctagc ttttctttca tatatttgaa ttgggataat gaatcattat attggtcttt
     1681 gatccaatca tcatacattt caaaggacat gtctgctgga agtatataga ggttattgat
     1741 tactttatag acagcctctt taggtggaag attgtttatc aacacgtcag tcacagtatt
     1801 ttcgtaaaca atcggttcac cttctccgcc tccttcttcg ttagtgaagt tcatatgcgt
     1861 taagttcatc acatcagaag tatttccttg catatccaag tcaattatca aggttctttt
     1921 tccttcatta actgctgatt caaaccctaa catttgcgcg cacgtacttt tacctacgcc
     1981 acctttaaaa ttaccgatta catatttctt cgctaccacg ttcctacctc ttttctttta
     2041 gcaatattca tttgatacta ttataacata tttattttta gttactacca aaaaaaagat
     2101 atatatgtac taccttataa ttaataagta aaaggtagta cataaataag gaaaagctga
     2161 aatatattga tttatagctt tcctcaaagt aatgacgtta tttaatttat cgagaagcag
     2221 agaatactcg cgactttagt catgtagacg aatcagattt tcgataaaaa agaagccgtc
     2281 cttcttaaga acgacaacaa atcactagat taattttttc aactgttcat aaaagttttc
     2341 atgcgttcca cataacaata ctggaataac cttgttttct ataatctcgt aagctactct
     2401 atatgttgtg cccgcatatt tgaacccact agaccaaata cctgataaat ccccagtttt
     2461 ttgttcaccc ttatatggat caatcgcaat ttcatcataa attaaattca aaaatttttc
     2521 tttcaatggc ttctctttta gctttttaaa tacttaatga catgttttga aggaacgatt
     2581 tcataagcca atttctgttg ccaactcctc tttagtcatt actttagaat tagtaagtgt
     2641 atcttcagca atatctctaa aggaagaatg cattttgttt tttctattct taaattctac
     2701 aagaatctca tctttatcgt agccttctgc aattatatca gacaaaatat cttcgctaaa
     2761 atcataaaat tctttttgtg gttcaacaaa ttcataaaga ataccattct ctaccaactt
     2821 tgcttcaact tcgactccat taggaacatt aaaatcttta ggtactgtca acatgattga
     2881 attgccttgt tttcttgttt ttgtaatcat ttaaatccct catttctaac agtatgtaat
     2941 tacttagtaa atacattata ccacgagata atgtatttac aagtaattac tgtgactcgt
     3001 aatgcgtcct tgctgaataa atttcaacca cgtgttcatc ttcatctacc ttataaacaa
     3061 cccggtgttg tctattcaat cttctagaat acctaccttc atgtgtaggt tttaacttct
     3121 caaatgattg ggtagggaga tagggatctt cctttaaagt ctgaataacc ttctcaaatt
     3181 gaggtttcaa attagactgt ttgattttct ttaaatcagc tttagccgag tttttaatca
     3241 tcacagaata gttattcatt ataagttatc ccaatcaatt tcatcaacat tagtaaatcc
     3301 actatcatct ttttctcgct tacgaacaac acccaaagtg cctatttgct caagtaatag
     3361 cgtttctttg attgctttcc aatcatccaa accaataagc accgcattat tttcactgcg
     3421 ctcactaatg atttcaattt ccgtatgatt ctcatttaca tctttcaaca acttataaaa
     3481 atttttccgt gctgagctag gatttaagac tgtttttgcc atatctactc cccctctaat
     3541 ttatatctcc attctaacgt acttaattaa gtacgtaaat tcgattgttt tgtttaaatt
     3601 ggagtaccaa aacagcattg taaagtgtta tccgtttcct ttatacccgt ggtgctagtt
     3661 aattttttcc tagaggaaaa tgtctaaaca tgttggtaaa tcaacaaaaa
//
LOCUS       DAZAOD010000163         3690 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000163 DAZAOD010000000
VERSION     DAZAOD010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.167"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(2..982)
                     /locus_tag="ACHDPO_002822"
     CDS             complement(2..982)
                     /locus_tag="ACHDPO_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFN3370381.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(1006..2490)
                     /gene="galT"
                     /locus_tag="ACHDPO_002823"
     CDS             complement(1006..2490)
                     /gene="galT"
                     /locus_tag="ACHDPO_002823"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFN3370382.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(2502..3491)
                     /gene="galE"
                     /locus_tag="ACHDPO_002824"
     CDS             complement(2502..3491)
                     /gene="galE"
                     /locus_tag="ACHDPO_002824"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFN3370383.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT          981 a          791 c          663 g         1255 t
ORIGIN      
        1 tttatttcgt tgattctcga ataatcaact ctgtttccac aataatcttt cttgaaaccg
       61 gtgctttgga attacttaat tgaagaatcg tctccactgc tagctctccc atccattcgg
      121 tataaacttt tacagtagaa agagagggcg ttacatattt cgctacactg acatcattga
      181 aacccatcac agaaatatct tctggtacca ctaaaccttt ttcttgaatc gctttcagtg
      241 cgccaatcgc taatgcatca ttagctgcaa aaagcgcatc aggaacatgc ggattcgttt
      301 ttaaatactg cttcactgct tgatatcctg actcgacaga aaaatctgct tcgataattg
      361 gaccttcgtc gtagcctttt tctgccaaaa cttgttgaaa tgccataatt ctgggatctt
      421 ttagccgctg atggtttttc ttcgtatatt ctgttccagc aagcatagcg atatgttgcg
      481 ctttatggga gacaaaatgt tcaatgactt tttgaacact tgacttaaag tcgacaacta
      541 gagagtcgat tccttgagaa gtgccgtcag aatctaccaa aagcaaggca ttttgggatc
      601 ctttcatttc taataactga gcttcgtcga attttcctag tgcgatcgtt ccatctgtcg
      661 gaagatcact aatggaatcc cacgtttctt tcaataaagt aacgtttgct tcttctgcct
      721 ttttttcgat tcctagacga atagataaat aataaagatc ttcaagctct tccgtatcgt
      781 cgtaccactg gatcaggcga agcgtttgct tagtatttgc tgcattttta cgatgtttcg
      841 tataatttaa gcgttctgct gcttcaaaaa ttttttgctt tgtggctaag ccaacggaaa
      901 gatcaggatc atagttgaga actcttgaaa cagtagcagg agaaactcct gccaactgcg
      961 caatgtcttt aattgttgcc atttgtctct cctccttttt tacgtttata aaattgcagt
     1021 aaatcgttca aacgctgcct gtcctttttc atctcgcttg aatactccag cgtcttccag
     1081 tacacgtgca aaaacctgac ctacagattt ttgtacgaca tcggtgaccg tatctttcgt
     1141 caaatcagga tgttcttttt ttaattgttc tgcccacgga cgatgatatt cagccatctg
     1201 gttttcttct cctaataaga aatgctctac ttctactagt tctggtttca aacgaggtgg
     1261 taaaacagca agccccatta cttcgatcaa cccaatgttc tcctttttga tatgttggac
     1321 atctttatgt ggatgaaaaa tcccatcagg atgttcttct gaaacattgt tgtctcgaag
     1381 gacaaggtcc aactcaaagt aattgtccct tcttcgtgca attggcgtaa tcgtatggtg
     1441 tggtgtacca tctgctgaaa aagctctgat agatactgtt tcatccgaat atgctttcca
     1501 cttttccaat actgagttag ctgcttcaat caacaatttt ttctctgttg attgcaaacg
     1561 gatcacagac atcggccatt tcacgactcc tgcgatgact tgcggataat ctgctagttt
     1621 gataagtttt tctatcggtg cttttgccat aggaaattca tgacgtcctg cctgataatg
     1681 atcatgagaa agaatcgatc ctccaacaat cggcaagtca gcattcgaac caacaaagta
     1741 atgaggcaag acttcagtaa tccgaagcag tctagcaaat gtttcctttg tgattttcat
     1801 cgggcggtgt tgttctgata aaatgatcga atgttcattg taataagcat aaggagaata
     1861 ttggaatccc cagctttcac cgtctagatt cattcgaata atccggtgat tggtgcgggc
     1921 tggatagttc aagcgacctc tatatccttc gttttccatg caaagcatgc aggtaggata
     1981 gtctactttt accgcctcgc gttctgctgc gatttgtttt ggatcttttt ctggcttaga
     2041 taaattgatt gtgatttcca gttcaccata ctccgactct gccggaaatt tgatgttttt
     2101 tgcgatggct cttgttttga tgtagtcatt tttcttactt aaattaaaga aatactcagt
     2161 tgcttcctct gggcttttcg aatagtgctg tgcaaagaat gcattgacga ctgaaggtgg
     2221 cggtgtgaga aaatccatta attgcgcttc aaaaatctct tgttctgctg gcaattctga
     2281 aagaacacca ttttctcttg ccttagcgac aagctgatcc aataagtcta cagattcttc
     2341 cttaactggt cttacttcaa tgctttctag agcatcttct cctaccatcc ctaaaagacg
     2401 attctgtaaa tataagcggt ccatttccat ccatccgcca gcttcgatcg caagtgtggc
     2461 aaaatcacaa atcgtttgac tgattgacat atctcattcc cctattcttc ataaccattt
     2521 ggatggctga catgccaatc ccatgctgtt ttgataattg ctttgatatc tgtgtattca
     2581 ggtttccaac ccagaacctc tctcgctttt tcacttgaag cgactaatcg gctaggatct
     2641 ccagctcttc ttggtgctat ttctgctgga atttcttttc ctgtcacttc tctagctgct
     2701 tctagcattt ccttgactga gtatcctttg ctgctgccta aattgaagaa gttgctttca
     2761 tttccttctt tcaagtattc caaagctaaa atatgtgcag caatcaaatc ttctacttga
     2821 acataatctc tgatacatgt tccatctggt gtatcataat cgtctccata aacagccaat
     2881 gcttttcttt gaccaagagc tacttgtaaa atgattggga caagatgcgt ttctggtgta
     2941 tgatcttctc cgatagatgc atctgctttt gctccggcta cattgaagta gcgcaaagcg
     3001 acatagcgca tgccatatgc ttggtcacac cacttcatca ttttttccat catcaattta
     3061 ctttcaccat acggattttt aggattagct ggtgtatctt ctgtgattgg agactctttt
     3121 ggttctccgt aagttgctgc agtagaagag aacacgattt tattcacatt gaactcgtgc
     3181 atgacttcaa gtaagatttg cataccgtat acgttgttgt tgaaatacat caatggtttt
     3241 tcgacagatt ctcctactaa agagcttgca gcaaaatgga ttactccttc aatcggttcc
     3301 ttttcaaata cggaacgtag aaattcttta tcccggatgt ctccttcata aaaatgagca
     3361 tctggatgta ctgcttgttt gtgacctgtg agcaaattat ctaccacagc tacttgatac
     3421 cccttttgaa ctagctggtc tacagcgtgc gaaccgatat aaccggctcc gcctagtact
     3481 aaaattgtca taaaaaacac tcctttgatt agtaaaattg tgtttgttga ttatatataa
     3541 tttaaaaaaa cgaagtttac ttttatggtg aaaacaaaca aagtaaaatt tcgtaaattc
     3601 atatggtaaa tttataataa aacatttagt aaacattttc aaggattttt tgcaaaggtt
     3661 tacaaacaaa cgtaaaacta gccttttttt
//
LOCUS       DAZAOD010000164         3662 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000164 DAZAOD010000000
VERSION     DAZAOD010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.168"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(278..955)
                     /gene="nth"
                     /locus_tag="ACHDPO_002825"
                     /pseudo
     CDS             complement(278..955)
                     /gene="nth"
                     /locus_tag="ACHDPO_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
     gene            complement(962..1660)
                     /locus_tag="ACHDPO_002826"
     CDS             complement(962..1660)
                     /locus_tag="ACHDPO_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFN3370384.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            1928..3112
                     /locus_tag="ACHDPO_002827"
     CDS             1928..3112
                     /locus_tag="ACHDPO_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFN3370385.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3118..3561)
                     /locus_tag="ACHDPO_002828"
     CDS             complement(3118..3561)
                     /locus_tag="ACHDPO_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFN3370386.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT          951 a          730 c          611 g         1370 t
ORIGIN      
        1 ttattacacc tttagataga tacgtcactt atttatataa tcctttggaa tactggactt
       61 attttatagg tatattggaa ggcattattt tctacatcgg gtattttccc aataaaaata
      121 acaactttta tttttatcgc aataaattgt aataagttac catcctagct actgagtatg
      181 tacatttact ttttcatgca aaaaagataa acgaaacagc ttttctccat aataacaaga
      241 taattcatac atttatttgc aattaaagaa accacgtcta caggcgtggt ttctttttta
      301 gcgccttttc ttttagacgc atccgatttt tcccatcttg acatattgat agcaaaggac
      361 atacctcgca cttgggattt cttgccgtgc aatgatatca accaaaaaaa atcagtgtat
      421 gatgtgtctt tacccataat tcttgtggta ctttccgcat cagtgtttct tctacttcca
      481 tgaccgtagc atctagtttg cagatcctca ggcgttttga gacacgttcc acgtgggtat
      541 ctactgcgat tgctggtatc ccgaatgcat cccccaatac gacatttgct gtctttctgc
      601 ctacaccagg aagagacatc aattcttctc ttgacgttgg cacttgccca tcgaaacgtt
      661 caatcagctg ctgtgcacac gctttgatgt tttttgcttt atttcgatac aaaccaatcg
      721 tttttatttt aagaatgatt tcatcgattg aagcttctgc taacgcatcg ggtgtcggaa
      781 aagaggcaaa caaatctggc gttgctttat tcactgatac atctgtcgcc tgggcactta
      841 agatcactgc aatcaataac tcaaatggat tattgtgctt gagttctcca tgtgcttcgg
      901 gaaacattcc atacatcgtt tctagagctt ccattgtttt ttgtttgctt aacatattcc
      961 gctactcctc caaccaattt ttcagtgaga ctttcggcaa ttcttcttgt tgagctgact
     1021 gttctacttc tctttgaaga agctgctgtt ttcttcgttt ttggtcttct tccacttgtt
     1081 gttttgtacg tagatttttt ctttcccacg atagcaaaat gcggtcaacg taattaaaac
     1141 tataagcctg atttaatacg gcttcccgca gtgctagctt caaaatttcc ggctgataat
     1201 ggtcttcttc tagccattgt ccgatccgct ggaactcgat cgaagaaagc gggcgtccaa
     1261 attcttgttc aaataattga tacactgact ggatttcttt ttcttgtgtt ttttcttcgt
     1321 attttttttc ttgtgttttt aaatactcac ctaatagatc atagatgggg taaagattat
     1381 atcgatctgc ttttttaccg ttgacaatcg tcgtttctat cttgataaat ccatttgtta
     1441 cgagacgatc cagtatttga aaaatctgat cttgtttgat tcccatatcc atagcaatca
     1501 tctgcaaatc agggaaagta tctccttcaa gctgtgccat atgcaactgt agaacaaata
     1561 aaaattcttc agattgtaga ccgatcctat gataattttt aagtaaaaga ttagatatga
     1621 ctgtttgtcc agcgcttaag taattttcta aattcaacat gatttctcct ccgctcaatc
     1681 acagtatacg taaaaaaaac atgggaagca agaacaggtt tcttttctat ttacttcact
     1741 gatcggtcag atttacaatg tcgtctactt gatttttgtt tgttcatgtt tttgatgcgt
     1801 atcttcactt ttcggaataa ataaattaag tagatttcgc tgttccttag aatgttgaca
     1861 aggaaacaaa attactatac actatttttg tttccaagtt aacattattg cataaaggag
     1921 tttttacatg tacagtttca caaataaaca ttctaaagtt tttggatacg tctctgtctt
     1981 attcactgga ttaggattta ctatcgtcag tcctgtactt ccgtttttaa cgctgcctta
     2041 ttctcactcc atacatcagc aagctttcta tatcactttg ctcatgtctg tttatgctct
     2101 agctgccttc ttatctgccc ccattctcgg tagcttaagt gatcattttg ggcgtcatcc
     2161 gatccttatt atcagtttat taggatcaag tatcggatat ttgctttttg gtttaggaaa
     2221 ttcgatatgg atgttgttcc ttggtcgtat cattgaagga ttgacggcag gagaaatctc
     2281 caccttatat gcttactttg ccgacatcac ggaacctaat gaaagaacca aagtttttgg
     2341 atggatgggt gctttagtcg gtataggaac aacgctgggt cctattatag ggggtctatt
     2401 agctgagttg gggaattctg ttcctatatt tattggagca ctctttactt tcttaaatgc
     2461 cgtttatggc tacacattta tgctagaaag ccttccaata aaaaaacgtt cagtagattt
     2521 aagtttctcc catgtaagac cttttcacca attacaacaa ttattcaaga tttcatccgt
     2581 tattccttta ttgacagcag gttttgctgt ttggttggca gctggctctc ttcaatctat
     2641 cttttctcaa ttttcgattg acgcctttca gtggaaggct gggttggttg gtttaagctt
     2701 ctctttgatt ggaatcttgg atactgtctc gcaattgttc attatgcctc gattgctcaa
     2761 aaaattttca gaacagcaga tcacaagaat agggatgttc agtgaaatcc tcgcctatct
     2821 attcatcaca ttatctggaa ttcttctact gccgattttg tttttatttg ggattatctg
     2881 ttatggtttc ggtgattcta tttttactcc tgtattcaat ggccaactat ccaattctgt
     2941 ctcagataac cagcaaggtc ttgtaatggg cggtacccaa agtatacaat ctctatcgcg
     3001 cgtcatcggc ccgctaatcg caggacagct ttatgctgca gcaccatttc ttccgacggt
     3061 attcggattt ttgcttatga tttttgccta ttatcactac aataaaaaat agtagcttca
     3121 tttgctactt cgtataaatt ctctgtatcg accgataaaa cgaaatactg tgtcaaattc
     3181 ttcttttgac atattttcaa atacagtagc atctcgctgt acccattttt gatggagttg
     3241 ctcgtgtcta ttccttattt tttgtccgat tggcgtcaat tgaaaataga tttctttttt
     3301 attctcttcg ctttgataag tgtttatgat ccctctagct atcagttttt ttgttagctt
     3361 actgatggct cctctagtca tgtaactagc attcgctaat tttgtcacgt taggatcagg
     3421 gattttcccg atatgttcaa tcacttctag ttcatttaga gtaaatcctg caaattcttt
     3481 ttccatttct ggtttattac gatgaataat ctcattagct aaatccagat attcttctat
     3541 tagcagttgt cttttatcca tttctacacc ttctttttct ttcattatat tgtttttttg
     3601 tttcctattc aacaaagata aaaatatttt gtaggaaaac ccaatctgaa accaagaaaa
     3661 aa
//
LOCUS       DAZAOD010000165         3388 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000165 DAZAOD010000000
VERSION     DAZAOD010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.169"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(63..2555)
                     /locus_tag="ACHDPO_002829"
     CDS             complement(63..2555)
                     /locus_tag="ACHDPO_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFN3370387.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(2562..3029)
                     /locus_tag="ACHDPO_002830"
     CDS             complement(2562..3029)
                     /locus_tag="ACHDPO_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFN3370388.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(3165..3238)
                     /locus_tag="ACHDPO_002831"
     tRNA            complement(3165..3238)
                     /locus_tag="ACHDPO_002831"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3202..3204),aa:Arg,seq:acg)
     gene            complement(3296..3369)
                     /locus_tag="ACHDPO_002832"
     tRNA            complement(3296..3369)
                     /locus_tag="ACHDPO_002832"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3333..3335),aa:Pro,seq:tgg)
BASE COUNT          924 a          750 c          557 g         1157 t
ORIGIN      
        1 cttgtcacaa cctcttaatc aagtcttact attataaaaa ttcagctaca caggccaagt
       61 aactataggg aacctactgt ttccttttta ggtccgcgaa cattcaatgt gatcttacct
      121 tttgaagcac ctactgttac gtggtcacct aaacgaattt ctccgccaag caaagcctcg
      181 ctcaatcgat cttcaatttc tttttgaagt gcgcgacgga ttggacgtgc accatattca
      241 ggatcaaatc cagctttccc gatcacatcg attgcagatg gtgtgatttt cacttgaata
      301 tcttgttctt tcaatcgttt gataatcgct ttgctcatga tttggacgat tgtatggatt
      361 tcatctttac tcaatgaatg gaagacgaca gtctcatcga ttcgattcaa gaattcaggt
      421 cggaaagctt tctttaactc ttctaagata cgtttttgca tggctttgtg atctttagta
      481 acatcttgga cattgaatcc gacatttttt tcttctcgaa tttgtgtcgc tccgatattt
      541 gaagtcataa tcatgattgt atttctaaag tccacttttc tacctttaga atctgttaaa
      601 tgaccatcat ccaatacttg cagaagtaaa ttgaaaacgt ctggatgtgc tttctccact
      661 tcatctaaga gaatcactga atatggtttt tgacgaattt tttctgtcaa ctgtccacct
      721 tcatcatacc ctacgtatcc tggaggagac ccgattaatc ggcttgtact gtatttttcc
      781 ataaattctg acatatcaac acggatcagg gcatcttcac ttccaaacat gacttctgaa
      841 agtgctttgg ccaattctgt ttttccgaca ccagttggtc caaggaacat gaatgaacca
      901 attggacgat caggatcttt caatccgctt cgtgcacggc ggatcgcacg tgaaactgct
      961 ttgacagcct catcttgacc aacgacacgt tcatgcagaa gtccttccag ttctaacaag
     1021 cgttcgcttt cttttttctc caactgctgt agagggacac cagtccactc cgatacaact
     1081 gtagcaacat cttcttctgt tacacgatca gaataacctt gctcctgttt tgcttcaatt
     1141 gcagaaactt tttgcagctt tttacgtagt gctttttctt gtctgcgtaa ttgagcagca
     1201 ttttcaaagt cttgtttttg gatcgctgct tccttttctt gtactagttc atcgatttct
     1261 agtttgatca cagttgattt tgttaagtga tcggtttgat ccaaacggac tttcgctgct
     1321 gattcatcga tcaaatcaat tgctttatcg ggtagttgac gagaagtgat ataacgaaca
     1381 gaaagattga ctgctgctcg tacagcttca tctgtgatct ccactccatg gtgctcttca
     1441 tatcttgtac gtaatccttg aagaatcact tctgcttctt caggagttgg ctcatctact
     1501 tgaatgcgag caaaacgtcg ctctaatgca gaatcttttt cgatatattt ttgatattca
     1561 tctagggtcg ttgctccgat cgtttgtaat tctcctcgag ctaacgccgg tttcaagata
     1621 ttcgaagcat caattgctcc ttctgctcca cctgcaccaa ttaaggtatg caattcatca
     1681 atgaataaga ttacttgacc atcattatag atttcgtcga tgaccttttt cattcgatct
     1741 tcaaattcac cgcgatattt cgtaccagca accaaagatc ccatatcaag catcatcagg
     1801 cgcttttctt gcatgtcttc tggcacttca cctaaaatga ttttttgagc taacccttca
     1861 gcaatggctg ttttgcctac accaggttca cccaccagta cagggttatt ctttgtccgt
     1921 cggctaagaa tctggataag ccgtttcact tctctcgaac gaccaacaac tgggtccagc
     1981 ttgttttctt ttgctaattt cgtcaaatca cgtgctaatg aatctagcgt aggtgttcct
     2041 tgcggtgttt gccgtttatc ttgtacattt acatttctac gacgattcat tccttttcca
     2101 gcagaatcac cagctagccc cattttttgt ttcagaactt gacgggcttt tgaaaggctg
     2161 atacctaagt tgatcatgat tcgagtagcc atgatacttt catcttttaa taagctcatc
     2221 aaaatatgtt ctgttccaac tttttgagaa ccagttttct tcacttcgct gctagctaaa
     2281 gcaaaaactt gtttcattct tggtgaatat ggaagaaaga ctcctttagg gtaagaacgg
     2341 ataccaccat aaccaatcag atgttcaatt tcttcataaa tttccgtttc attcaaatcc
     2401 atttcacgta atacttttcc agcaattcca ttttgctcga ccactaaggc tagtaaaaca
     2461 tgttctgaac taactgattg atgtttcaac cgttttgctt cttcttgtgc aatttctaat
     2521 actgcttggg ctctttcagt aaaaagttct tccatctaat ctcacttccc atcttcataa
     2581 cttaaacgtt ccagaaatgc tcggagaatc cgagcacgtg tatgatcttc atattcattg
     2641 aaattcaatg tgttttttgc aattgcactc aacatcaagt ttccttcttt ttttgtaatt
     2701 atttggtctt cataaagttt ttgaataata gcaaaagcat ttttctcact gattgtatca
     2761 tcaaataact gatttatctg ctcaagtaat tgttttttat ctgaaatcct tacttttgca
     2821 attcgtatat aaccaccacc accacgtttg ctttctacta gataaccacg ttggatggta
     2881 aaacgggtat taatcacata gttgatttgt gaaggaacac agttaaagag gtctgccatt
     2941 tcaatccttc gaatctcgat catttcacta ttttccagaa ttttctttat atatgattca
     3001 attaaatccg aggtattctg atgtgccatc ttattcattc cctttgacta atattgacct
     3061 taattataac gaatttgata atagaaagaa agaagaacgc tttttgttaa ataaatcctt
     3121 tagaatcaac aaaaaaaaat acggaatata ctattccgta tcgacgcgcc caagaggagt
     3181 cgaaccccta accttttgat ccgtagtcaa acactctatc cagttgagct atgggcgcat
     3241 attcaattta aaaaaattat aaatcatttg aaaacaaaaa gcaagataaa aaaaatcggg
     3301 aagacaggat tcgaacctgc gaccccttgg tcccaaacca agtgctctac caagctgagc
     3361 tacttcccgt ttaaaaaata aaaaagac
//
LOCUS       DAZAOD010000166         3362 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000166 DAZAOD010000000
VERSION     DAZAOD010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.170"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(45..302)
                     /locus_tag="ACHDPO_002833"
     CDS             complement(45..302)
                     /locus_tag="ACHDPO_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFN3370389.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            460..723
                     /locus_tag="ACHDPO_002834"
     CDS             460..723
                     /locus_tag="ACHDPO_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370390.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            747..935
                     /locus_tag="ACHDPO_002835"
     CDS             747..935
                     /locus_tag="ACHDPO_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370391.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(1018..1203)
                     /locus_tag="ACHDPO_002836"
     CDS             complement(1018..1203)
                     /locus_tag="ACHDPO_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370392.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            1418..1789
                     /locus_tag="ACHDPO_002837"
     CDS             1418..1789
                     /locus_tag="ACHDPO_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFN3370393.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(1939..2011)
                     /locus_tag="ACHDPO_002838"
     tRNA            complement(1939..2011)
                     /locus_tag="ACHDPO_002838"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1976..1978),aa:Gln,seq:ctg)
     gene            complement(2057..2485)
                     /locus_tag="ACHDPO_002839"
     CDS             complement(2057..2485)
                     /locus_tag="ACHDPO_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370394.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(2545..3303)
                     /locus_tag="ACHDPO_002840"
     CDS             complement(2545..3303)
                     /locus_tag="ACHDPO_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFN3370395.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT         1116 a          536 c          627 g         1083 t
ORIGIN      
        1 tttgctgcat ctttaatcgt tttcttttta aacatgcgag ggattcaatt ctgattctta
       61 tataaaaaat agatccaaat aataagaaaa attactgaaa gcgtcaattc gatgatgtgt
      121 gttattaata cagacgttgt ttcccaatgc ctaaaagaaa aaatttgata agtaaaatat
      181 acagcaggta aagaggccag taaaactgaa aacttctttt ttgtccattt tatgtaatag
      241 aaaagaatgc ttatcataat aaaaaaagga atataaaaaa caaattgacc gatcgcgatc
      301 atactattgc ctccgataaa taaagtccat gatacaaaat aacactttgt gcgaaatggc
      361 gcaagcagtt ttgtggattt atccggtaaa atctgtatcg attttgaaat tagaggagaa
      421 acttgctata atcaaagtga aagaaggagt gggattttca tggatcatgt agtgttagaa
      481 atcgatttgc atttgatcaa taatattcgg gtgatttact atgttgtaag taacagtgtc
      541 gaacaacgtg tactgacgaa taaaataaat ggtattttag caaagaaaga cgttcaccga
      601 ttcaataatg gtgaaggaag ttattatagt atcccagtag aaaaaattat ttatacgaca
      661 gtcaaagtca gagaagatct agataccaaa aaagcatatg aacctatttt tacaacttat
      721 tgattgacag cagatggagg aaaaaaatga atccatatga acaacttatt caagatttga
      781 tcgatggaaa aatcgaaaag attgatgtaa aaagagaaga attaatggct tttcgagaag
      841 cgtggctgaa gttggagaat cgtaaatatg tggtgggaaa agcctcactg aacggcaatg
      901 tgacttatca ttacgatccg acacgtttat tttagtatga agtattcaga aaagaaccaa
      961 aggaggacga tgcagcagca ttgtcctcct ttgattttac aaaagtgaaa gttttactta
     1021 tttgaataga tttttaaatt tgtttttgac actgtcgata tttacatctt ttaaaagatt
     1081 ttgggctttc tctttataag gtcctaattg ttctttatgt tcttcgataa atcgttttgc
     1141 gccatcgaaa ttgccgttct taatcatttc cttgactttt tgaaataatt cttcttgatt
     1201 cattttgaac acatcctttg ctatcaacat gattttttac atggacaaaa cgagaaaaac
     1261 tgatttatcc acacgtcaat aatatcaaat aacgatcatt tttactaaaa aaacactcga
     1321 ttctcgcttc taaagtagga gaaaaatctc caacttggga cggatggaat ttctttaact
     1381 gacccatata ctgaatatat aacaaggagg tagaaagatg aaagtgatta aatatttgat
     1441 tggactggcg gcgattagtg gtattttgct atttggactg aaatattata ctgaaggaag
     1501 ttatggagaa atccctggta tacttgatca gctaaatcca ttagttgaaa aaggagaggt
     1561 ctatgtaaag acacaaaaac cagaggaagt aaatgaatat ggtacagcaa ggtatgtgca
     1621 gaaagctgct gatgccaatg ggaaagaacg aacggttgaa tttaatggtc tttctgtgtt
     1681 aaaagaaaat cattatttga aaattagcaa taaaggagca cacatagaaa cgtatgagga
     1741 agttcctaga gaaaaagttc cggagaaagc attagcaatt attgggtaaa tcagtttttg
     1801 tattaagaat acgcccgatt ttattattca taatttaatt atgtaaacta aatacaagta
     1861 gtaaaaataa tacaataatc cccctgcaaa aagattgttc ttttacaggg ggttcatttt
     1921 ttcagcaagc acatcaaatt gggatggcag ggttcgaacc tacaattgct tgattcagag
     1981 tcaagtgcct taccagtttg gctacatccc atttattcaa caaaataatc atagcacttt
     2041 cctaaaaaaa cgcaagttat ttttcttgat cggatagttg ttgctttact cgtaaaaggc
     2101 ggcgtactag tttcttttct aatccagcag gaagggcaat cagttctgct actgacaaga
     2161 cggtgtccaa taactgatat tctttgacag gttcattcat aatatgatag atgtttgcta
     2221 aacgttcaat atattcaaag cgagtatact ctgttcgagc aattagaaat ttcaataaat
     2281 cggtggcttt ctcgtactct tgatctgcgt aataaacaag agattgacga tacaatttga
     2341 tttccagttc attgagggta gcaggtctgc gacgctcgtt ccactcatta atagagactt
     2401 taccttgaac atttcccttg cagtcacgga caaaaataat cggaatttca tttggatcca
     2461 tttttttatg tgtgaatttt tccattatct acgctccctt caaaggtttg gtatcttgag
     2521 tataagggat ttttgtttga attactagct tttctccaaa gttagcatct gtccacccat
     2581 tgcagtgaaa atcgccgaaa aatcgttgat cggtactgct cgatttttta caccataggg
     2641 atcgttgaca taaatatttt ctttgtcata tccagtgact acacaagcat gaacaagagg
     2701 agtgactctt acttctccat tatttgtggt ccaagtcata aaatcagttt catctgggac
     2761 ttcaaaattg atagtcacag aagtccagac aggatttcct ttagatagtg cttttttgat
     2821 atcatcgagt tgagcatcgg tttttggaaa agtgtgataa tccgtttgga cgatttgctg
     2881 agcaagggag gcaactgggg gaacatagac gaccatagcc cagtctccgc cactgatatc
     2941 accaacaaat ccttcattag gatcgccatg agtcccatct gcattgaaaa cagggacgta
     3001 atccaattgc tcagctaact ggtttttagt tgtttcataa ccataaaaag ataaaagcat
     3061 agaaagcgaa gtgacttcac agccattttc taaagaagga gaatcaaact ggctctctaa
     3121 tggaacatct agtaaaactt ctgctttctc ttttgtcttt ttcgtttttt gtgttgaact
     3181 tttttgtgca gtgttcattg tatgttctgg agaatggata tgtaggtaat aacttgtacc
     3241 gcttaataaa agagcagctg tgccccctag aaacaatagt tttttgaacg tttttttctt
     3301 catttgaaat ctcccttttc agctgtttat ctttcctatt ataaatgtat ttttattgga
     3361 aa
//
LOCUS       DAZAOD010000167         3330 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000167 DAZAOD010000000
VERSION     DAZAOD010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.171"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2232)
                     /locus_tag="ACHDPO_002841"
     CDS             complement(<1..2232)
                     /locus_tag="ACHDPO_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFN3370396.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="ACHDPO_002842"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="ACHDPO_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          914 a          745 c          537 g         1134 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata
//
LOCUS       DAZAOD010000168         3322 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000168 DAZAOD010000000
VERSION     DAZAOD010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.172"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            142..606
                     /locus_tag="ACHDPO_002843"
     CDS             142..606
                     /locus_tag="ACHDPO_002843"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFN3370397.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            620..1369
                     /locus_tag="ACHDPO_002844"
     CDS             620..1369
                     /locus_tag="ACHDPO_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFN3370398.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            1369..2199
                     /locus_tag="ACHDPO_002845"
     CDS             1369..2199
                     /locus_tag="ACHDPO_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFN3370399.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            2199..2846
                     /locus_tag="ACHDPO_002846"
     CDS             2199..2846
                     /locus_tag="ACHDPO_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFN3370400.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(2944..>3322)
                     /locus_tag="ACHDPO_002847"
     CDS             complement(2944..>3322)
                     /locus_tag="ACHDPO_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HFN3370401.1"
                     /translation="WEDGAPMGIDNFFASEEKFPTLFEKGSQYTSLYKLLEDDYDVKA
                     TSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQPFHYSQSTVRCDRISYV
                     IEVTENITLDTVHKNDSDPKVID"
BASE COUNT         1117 a          441 c          620 g         1144 t
ORIGIN      
        1 aatctataga agaaatagat tttaaggaat tactgaataa ctctcaaaaa agtatggttc
       61 atattaattc gcttttaaaa gatgtcagtt aaggtggcaa tttctattct ataaatttta
      121 aaaattgaag gaggaaatag aatgattaaa ttagtgcgtg tagaccacag attacttcat
      181 ggacaagtaa tattttcttg gactaaacag tatgatatta accatattat tgtggctgat
      241 aacaaagttc caggagatcc aatgtctgtg atggctttga caattgctaa acctgctgat
      301 tgcaaattag acattgttaa aattagtgat gttaaaggga ttatggaaac atccccaaat
      361 gataattaca tgattttaat taaaggacct aaggaagctt ttgaattagt tcaaaattta
      421 ccagaaatta aagaaattaa ttttggcggt gtgtctaaga aaagcgagtc caaacaatat
      481 ggaaaggcag tctttttaac tcctgaagaa ttagaagcca caaaaaaaat tcttgatcaa
      541 gaagtgaaaa tatttgtgca acaagtccca tcttcaagta ttgaaaatgt agattttagt
      601 aagtaagggg ggaaaataaa tgttattaaa agccatttta ttaggtttag ttggtgtggt
      661 agctgttatt gactccaggt taattggtcg acaaaatatt ggtagaccac taattttgag
      721 tacacttgcc ggacttgtgc taggtgactt gcatacaggg attgttcttg gggcatcttt
      781 agaattaatt tctatgggat tcgtctcaat tggggcggct ggacctccta atatgcaact
      841 tggtagtatt attgccactg cttttgcaat tttaactaat agtagtacag aaacagcctt
      901 aacaatagct atcccagtgg ctgtagctgg tgaatttatg agtattatca tgcgcatgat
      961 aattgctcaa tttggacatg ctgcagataa agccattgaa aataataaat ttagaaaagc
     1021 tcaaattatt catatttatt ggtcatttat ttttaatgct tttgtttact ttattccaat
     1081 ctttttaaca gtatattttg gtgctgacgt tgtggcagat ttagtagata aaattccaga
     1141 aatgattaca gacgccttga ctgtctctgg aaatatgctt tccgcattag ggtttgcaat
     1201 gctattaagc acaatgttga gtaaaaaatt atatccttac tttatttttg gattctttat
     1261 tgttgcctat tcaggtcttt cactaattgg cgtgacaatt tttgcagctc tgattgcctt
     1321 tgtaatggat caagttaaat atggaaaaag agaagaggcg catggttaat ggaaaatagt
     1381 acagaaaaaa aacgtttaat cacaaaaaaa gatcttaata agatgtgtct tcgttcatgg
     1441 acaatcatgt gttcgtggaa ttatgaaaga caaatgcata tgggatttat gtatgggatg
     1501 gcgccaattt taaataaagt ttataaaaat gatgaagaga aaaaaagaga agcttatact
     1561 cgtcatatgg cattttttaa ctgtacgcct caaatgactt catttattat gggactttgt
     1621 gcttctatgg aagaacaaaa tgctcaagca gaagaaggaa actttaatac tgaatctatc
     1681 tccatgatta aaaccagttt aatgggtcct tttgctggaa ttggtgattc atttttccaa
     1741 ggtactttaa gaattattac atttgggatt ggattgtctt ttgctaagca aggtagtatt
     1801 ttaggaccga ttttagctgt tggccttttt gctatacctt ctattttagc tgttttttac
     1861 ggcggtaaat taggatatga gtctggcaat aaatacctta ctaaattgta tcaagaaggt
     1921 cttatggatc gagtaatgca atttgcttct atcattggtt tggctgtagt aggtggaatg
     1981 gtggctagca tggtgccaat tgtcacccct ttaaaattca ctacaggggg aacagaactt
     2041 gttttacaag acttacttga ttccattatt cctggattat taccacttgt atgtactttg
     2101 ggaatatata aattgattaa gaaaaatgtt agtacaaata tgctcttatt aggttgtatt
     2161 ttggcagggt ttgttttaag tataataggt atcttataat gattaaggct ctaatttttg
     2221 atatggacgg agttttaatt gatagcgaga ttatgtatca aaagtgggta tttaattttt
     2281 taaaacaaga aaatttaagc tatcctttgt attcttatca aaaaaagatt ggaactacag
     2341 caagtatttt tgatgatata gaaaagtaca atgagggatg taacagttta gaattgaagg
     2401 gaaaatttac taaatattgg aaatcgcaaa agattgatta cttggatatt tttcctaata
     2461 tactaattga acagcttgaa tggttaaaaa agaaaaaaat aaaaatggca attgcttctt
     2521 ccagtccaat ggatactata aatgaagttg ttaccacttg taaaatagag tcatattttg
     2581 attgtttaat tagcggaaga gatttgccag aaagtaaacc taatcctact atattcctta
     2641 aagcttcaga acagctcaga attccagttg aagaatgtct ggtgatagaa gattcttata
     2701 atggtataaa agctggtaaa agagcaaata tgaaggttct tgcaattaaa gataaacgtt
     2761 tttctcaaga tgtaagtcta gcagatgatg ttatttacga tattaaatat ctgcgacaag
     2821 aagtacaggt gaaatttgga atataaataa gttttttgat gtatttagag aatattagta
     2881 aaaataaaaa tcatgcccaa atctaatcaa aattgattgc tttgggtatg atttctttta
     2941 atatcaatct attactttag gatctgaatc atttttatgc accgtatcta aagtgatatt
     3001 ttctgtgact tcaataacat aactaattct atcacaacga actgtggatt gagaataatg
     3061 aaatggttga ttatttttat ctttgccaac cttttctaaa ataaatagcg gatctcctac
     3121 tatacattgc aataagtcgg aaagctcagg tgttgcagat aaaccgttta tttccataat
     3181 agagctcgta gctttgacat catagtcatc ttctagaagt ttatataatg aagtatattg
     3241 gctacctttt tcaaataaag ttggaaattt ttcttctgat gcgaaaaaat tatcaattcc
     3301 catcggggca ccgtcttccc ac
//
LOCUS       DAZAOD010000169         3144 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000169 DAZAOD010000000
VERSION     DAZAOD010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.173"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..201
                     /locus_tag="ACHDPO_002848"
     CDS             <1..201
                     /locus_tag="ACHDPO_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370402.1"
                     /translation="LFNLIKLDAKISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVG
                     LTFSEKLNNYKLIDYKYLSESN"
     gene            818..>3144
                     /gene="esp"
                     /locus_tag="ACHDPO_002849"
     CDS             818..>3144
                     /gene="esp"
                     /locus_tag="ACHDPO_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFN3370403.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         1149 a          464 c          607 g          924 t
ORIGIN      
        1 ttatttaatc tgattaagct agatgctaaa atatcaagtt atttattctt tttgatacat
       61 gatgaattta tggattatca aaaattggat cagttaattg aaagagaaag ctgggaagat
      121 tattacgtgg gtctaacttt ttcagaaaag ttaaacaact acaagttaat agattataag
      181 tatttgagtg aaagcaatta attattcatg tagagtacta gacactttaa atatggacaa
      241 ttcaattata aagaaaaaga atcaataatt taatgaggct gtgacaaatg tcattttttg
      301 tttcgctaaa aacgagtgaa aaaatgttga taactccaat cattcgttta agattctagg
      361 aatcattcag aaatgctgtg aaaccgatac tttataatta taaagaaggt gatttcaaat
      421 tccgaagaag gaatttgaag tcaccttttt acttatgtca cagtctcatt cagtaatgcg
      481 ggataaggct ccttattccg ttatttgaat actctgaagt ttaatctaag aaagggtaat
      541 attttgaaaa catgcttcat cgcatagaaa tgaacttaat ttcagaaaga atacatacat
      601 atctttttat atgttttcag ctgctgaatg gttaaaaagc acaaatatcc gaaaaaaaca
      661 tgaagaaatg tacttttttt gttgtaatgt tcatgaaatt ctctaagtaa attagttaac
      721 ataaggttag taagattcct attctgtgaa taatacgtat cagatttatc ttttattctt
      781 actaggaaag taattattaa gggagttgat ttgaataatg gttagcaaga ataataagag
      841 agtatttcta gaaaaaacaa agaaacgagt attgaagtac agtatcaaaa aattaagtgt
      901 tggggttgca tctgttttga ttggtgttgg tcttgtcttg ggaacaactg aactagttaa
      961 agcacaagat gaaatttctc caagcagccc acttgaaaca gcgataagct ccgtacaagt
     1021 aggtgacaaa gtagcttcgg ggaatacttt tcaggagaat cctggttata cgaaaaatta
     1081 taacttttcg gatttacaat ttagtcctca agaactaact ggagacacac taaaaggcaa
     1141 tacaattgga tttgaagttt acggaaaaca taatattgca gcatcaacta aaaactggga
     1201 aatccgtctt caattagatg aacgattagc taaatatgta gaaaaaattc aggtcgatcc
     1261 aaagaaagga attggatctt ctagacggac ctttgtaaga attaatgatt cgctgggtag
     1321 acctacaaat atttggaagg tcaattatat tcgtgcaagt gatggattat ttgctggggc
     1381 agaaacaacc gatacgcaaa ccgctcctaa tggggtaatt acgtttgaaa agagcctaga
     1441 tgaaattttt aaagagatag gcatagacaa tctcaagacc gatcgtttaa tgtatcgaat
     1501 ctacttggta agtcatcaag acgatgataa aattgtaccg ggtattgata gtacgggcta
     1561 ctttttaaca gattcagatg atttctataa tagcttagat gtatctgaaa ataatcctga
     1621 ccagtttaaa catggatcag taagtgcaaa atatgagaaa cctaatactc aaacaaaaga
     1681 tggttcagga tccacaggtg ctaatggagc tataatctta gatcataagt taacgaaaaa
     1741 ttataatttc tcatattcat cttccgcaaa gggcacgcct tggtatgcta attacaaaat
     1801 tgatgaacga ttagttccat atgtagcggg tatacagatg cacatggttc aggctgacaa
     1861 agtaacatat gatgtttcgt ttgaatccgg aacaaaagta gctgatttag caatcgagcg
     1921 acgggaaggt catgaaaatt atggcatagg ttcaataact aataatgatt taactaaact
     1981 tatcgatttt gctaatgcaa gtccacgtcc agtcgttatt cgatatgttt tacaattgac
     2041 taagccatta gatgaaatct tagaagatat gaaagcaaca gcacaagttg aagaaaataa
     2101 accatttggt gaagatttca tctttgattc ttggttgtcg gatacgaata aaaaattaat
     2161 ccagaacact tatggaacag gttattatta tttgcaagat attgatggtg atggaaaccc
     2221 tgacgataaa gaagagagcg gagacacgaa tccatatatc gggaaacctg aattagaaga
     2281 agtatatgat gttgacacaa cagttaaggg gaaagtattc atccacgagt tagcgggaac
     2341 aggtcacaaa gcccaacttg ttgataaaga aggtactgta ttagcagaaa aaactatcgc
     2401 tccaaatgaa aaagatgggg ctccaatttc agatactgta gaatttgaat ttacgggtgt
     2461 agattcaagt aaattaatcg cgaaagatga attaaaaatc caaatcgttt ctccaggttt
     2521 tgataaacca gaagaaggtt caaccgttat taaggaatca ccaaaagcgg ttgataaaca
     2581 aaccgtggta gttggattta aaccagatgc taaagaatca attcggaata ataaaaactt
     2641 acctgaagat gcagagtatt catggaaaac agagcctgat acttctaacg ttactgatag
     2701 tacgaaaggt attgtaactg ttaagatcgg aaatcgaact ttcgacgtgg atgtagagtt
     2761 tgctgtaaaa gcttctcaag ctatggaaaa tgatgcaaca tacgtaccta taacaacaac
     2821 tccagaaacg acagttcaaa gtggaaaacc tacatttgat aaaccagatg ttcctttagc
     2881 taaagatgcc ttttcaattt cagatgtcta taataagtac ttcggtaatg caagtgttga
     2941 tgcaaacact ggtattgtta cattcactcc agctaaaggt gtaggagaat cggagccgat
     3001 tactggaaca attcctatta aaattgttta ccaagatggt tctgtaggca cgaccgattt
     3061 agcagtaact gtaagtaaag atatttatga aaatccagga gaaaacattc ctgcaggcta
     3121 ccacaaagta accttcaccg cagg
//
LOCUS       DAZAOD010000170         3127 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000170 DAZAOD010000000
VERSION     DAZAOD010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.174"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(133..858)
                     /locus_tag="ACHDPO_002850"
     CDS             complement(133..858)
                     /locus_tag="ACHDPO_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370404.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1012..1338)
                     /locus_tag="ACHDPO_002851"
     CDS             complement(1012..1338)
                     /locus_tag="ACHDPO_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370405.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(1375..1740)
                     /locus_tag="ACHDPO_002852"
     CDS             complement(1375..1740)
                     /locus_tag="ACHDPO_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFN3370406.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(1777..1992)
                     /locus_tag="ACHDPO_002853"
     CDS             complement(1777..1992)
                     /locus_tag="ACHDPO_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3370407.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            2121..2456
                     /locus_tag="ACHDPO_002854"
     CDS             2121..2456
                     /locus_tag="ACHDPO_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3370408.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(2532..>3127)
                     /locus_tag="ACHDPO_002855"
     CDS             complement(2532..>3127)
                     /locus_tag="ACHDPO_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370409.1"
                     /translation="SNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEWVKIC
                     FNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVCERLR
                     NVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGIDEVI
                     KELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
BASE COUNT          973 a          620 c          433 g         1101 t
ORIGIN      
        1 caaataaata tagtcgggct ccaaatccga aaaaaaatac ccccagtagc ttatcctaag
       61 ctactggaga tgtataagta cggtcatata acaacggggt agggtaaata aatgaaaaag
      121 atggaagaat cattattcaa taactttttt aaatacttcg ttgtaatcag ttacctgtcc
      181 gttcttaaat accacagaat aatctttttt cccattttca agtaaccgaa gtggaatatc
      241 tttaccaact ttctctgtca ctgcattact gatacctgtt agattagcta ataaatctga
      301 taaagattga gcatctgtag aaatctctgt atcagtattt atcgtgattc ctttatcttc
      361 atttacaagt ttccaagtag gtggtatagc tgtgtatgtt tctacaaatg aattaagttt
      421 ttcattaagt gacttctctt ttatatttcc atctaaaaac tctgtatata tggcttgagc
      481 tatactaaaa caaagctggc cttgttctaa taattttaca tcattagtta gtaaagctgt
      541 gttcacgtta tcaatcgctt caagaagagt atctttggtg tccctaacag ctttaggtgt
      601 gccttctgga atttccctac ttgatacctc gtccatttta tcttccataa accccttaaa
      661 atcatatctt tctcccaaat ccatagaagt ttttgagaaa gctttcattt ctgagtctat
      721 ttcttcaata atatttaaca tgtctgatac atattgttta ggctgattcg tttttaatct
      781 atatgtggta aatatctcaa ttcctccaat tatcaataaa attgccaaac aaatccataa
      841 taattttttc tttttcattt ttcctcctat acactgctgt tataacagtg actaatgtaa
      901 agattttccc agcaatcatc agactattat ttacagggaa tcaaaaaaac tccttagtaa
      961 gcttacacct ttaggagttc ctgtttgaac ggtatgcata atacatttaa atcaatttaa
     1021 cattaacacc tcagtatatg gtatctctac atatacacgg tctttttttg gatagtactc
     1081 gacatttata ttgatagcac ttccattgtc taacgtagct ttagcccggt acgtgttatc
     1141 accattatca tgagtgatcg tcacatcatc acatgtccga tttaagttat actgttcttg
     1201 taaaatctga gttaccaatg gtacagatga cttctctagt ccagatgaac ccgtcattct
     1261 tgaaaaaatt atacctataa tagccaatac aacgatacct ataatgacaa acttcttatt
     1321 catatttact ttattcaact ttttatctcc tatctccaaa atgattttct ctcatcagta
     1381 actcattgac atccccaata gtacaccaaa gatggctcca gctacccctg ctatcatcaa
     1441 aatcgtaccc atttgttcat ctttctctcg atataagtaa cccataataa cagcaacagc
     1501 accaaatacc acaggaataa atgctaatga tactaccata gaaatccaac caataatcaa
     1561 atacagcttc cctgtctctt gtccatgtac gatttgttcc ttcatttcat taattgtctg
     1621 ctcagtactt ttctttactg tgtctgttcc ggttgtctca tctgtttctt gtaatgctcc
     1681 gcaaaactgg caatacttac tttcatttgt tatttcttta ccacattttc tacaatacat
     1741 gtcttctcct cctaaaatca ttcaattgct tattagctaa ctgtttactt tattaaatac
     1801 atcagaaaac agctcattta ttggtacact taatatctca gaaagcattt tcatttgata
     1861 gggtttagga atcgttctcc ctgtttgcca cgaacttaca cattgctgtg taacattcat
     1921 ttttttggct aactcagttt gggaaagtcc tttttctttt ctgtatcggc tgagattact
     1981 tacttttttc atgattctcc cctcctgttt tattatatac aacaatatga tgtatttcaa
     2041 ctcataaaat atataaatac ttcaaatgtc attacaaata caacaacttg ttgtactcta
     2101 ctgagaaggg gggtgtatta atgaaacaga agcaatatgc aaaggtcatt agagaaaagc
     2161 gaaaagcact cgggtggaca caaaaagaat tagctaaaaa aatcttctct acacaacagg
     2221 cagtagcaag atgggaaaat tctgtaacag aacctaacct cgatagctta acagctcttt
     2281 ctagagccct aggaacccct gtaagccatt ttctagacaa tgttgacata gattatgagg
     2341 aagagttttt ggctctctat cgctctctta gtactgaaga tgcaattcga acaattgact
     2401 atatgaagct attaaaaagg caagaaaatg aacgcaatca gctattgaaa gattgaaaaa
     2461 taaataaccc accgaacttt aacggtgggt gtattgagat gaaataagat taagagctat
     2521 ggataacctg tctagtttaa tataattggg tctcttctat tccttactct ccgtccatca
     2581 tctcttgtta cacttgtaaa ttgataaata ggaactaatt caactcctga taatatcaat
     2641 tcttttatta cttcatctat ccctgcccct ttcgctagat atactaaaaa actactgctt
     2701 gctttcacat tgtatagttt cttaatatcc ttagaagctc gttcaagagt gaatccttgt
     2761 ttaacaaagt agcctctgtt ttctattaaa gcatttttca cgctgttatc cctgacattt
     2821 cgtaggcgtt cacaaacagt gttaataagt tctttttctg tcattagata tgtcccttgc
     2881 cacgataagc cctgtaaaac ttcatgtgct tcatctaaaa tcaattgttt ttccttgcta
     2941 agttctgatc gggaattttg aggaaatact cttttagcct ctttttcgtt aaaacatatc
     3001 ttaacccatt cataagaaaa atattgatat gtaaaatgaa atttttccag aagtggaagg
     3061 atatcttcat tcaatttttg aatcacagaa gttgcattaa aaacgtctaa tcgatagaca
     3121 ttgcttc
//
LOCUS       DAZAOD010000171         3036 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000171 DAZAOD010000000
VERSION     DAZAOD010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.175"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(554..2167)
                     /locus_tag="ACHDPO_002856"
     CDS             complement(554..2167)
                     /locus_tag="ACHDPO_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFN3370410.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..>3036)
                     /locus_tag="ACHDPO_002857"
     CDS             complement(2308..>3036)
                     /locus_tag="ACHDPO_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3370411.1"
                     /translation="LFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFSID
                     QEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCLQK
                     IQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLLEQ
                     LAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGFHS
                     IHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT          977 a          535 c          529 g          995 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataa
//
LOCUS       DAZAOD010000172         3033 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000172 DAZAOD010000000
VERSION     DAZAOD010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.176"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1087
                     /locus_tag="ACHDPO_002858"
     CDS             <1..1087
                     /locus_tag="ACHDPO_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3370412.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="ACHDPO_002859"
     CDS             complement(1305..2447)
                     /locus_tag="ACHDPO_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3370413.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="ACHDPO_002860"
     CDS             complement(2452..2637)
                     /locus_tag="ACHDPO_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFN3370414.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
BASE COUNT         1012 a          544 c          469 g         1008 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta att
//
LOCUS       DAZAOD010000173         2727 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000173 DAZAOD010000000
VERSION     DAZAOD010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.177"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1327
                     /locus_tag="ACHDPO_002861"
     CDS             <1..1327
                     /locus_tag="ACHDPO_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFN3370415.1"
                     /translation="NETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPTDN
                     WSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFASIL
                     TVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFGMR
                     FPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLRLF
                     SYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTTDF
                     IANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSFPI
                     LVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHNVS
                     TLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            1293..1643
                     /locus_tag="ACHDPO_002862"
     CDS             1293..1643
                     /locus_tag="ACHDPO_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370416.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1735..2154)
                     /locus_tag="ACHDPO_002863"
     CDS             complement(1735..2154)
                     /locus_tag="ACHDPO_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFN3370417.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(2155..2499)
                     /locus_tag="ACHDPO_002864"
     CDS             complement(2155..2499)
                     /locus_tag="ACHDPO_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFN3370418.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
BASE COUNT          695 a          521 c          490 g         1021 t
ORIGIN      
        1 aaacgaaact gacgttattt atattcatcc tcaaaaacga atcgtttcac agaaaagaaa
       61 gtatttttat cttggtttta caggtgtttt ttttcttttt attggcttgc tttctaatac
      121 tcctactgat aattggagtg gattgctaac tattcttacc tcgccaagca atcttttgac
      181 agattatttt gctttaggtg ttttcggaag cgcattcata aatgtaggga ttttgacctt
      241 actttctgtg cttttagctt atcggcacaa ggtgatttta aacggtccct tatttgcttc
      301 gattctaaca gttaccggtt tctctttttt tggcaaaaac ctttataatt ctatctcaat
      361 cattttaggt gtgtatctat acgctgtatt tgtcaataaa cctttttctc agtacatcat
      421 gatcggactg tttggtagcg tattatcacc ggtcgttagt tatatcactt ttggtatgcg
      481 ttttccttta ctgataggta ttttattggg gaatttagct ggcatagcaa ttggtatact
      541 tcttccgccc ttagctgctc aaactttagt tttccatcgt ggattcacac tttataatat
      601 tggattcacc tctgggttga ttgcgatgac ttttactgct gttttgaggt tattcagcta
      661 ttcaatcgtc gaaaatacat tggttttcaa tgaatatcac tttcctctca tttggattat
      721 ttttggcttt ttttcgctga cagtcggaat tggtttctat tataattcct ttcggctttc
      781 ggggattcga gaaattttcg attcatctgg aaaattgaca actgatttca ttgctaattc
      841 tggtattggt gctactttga tcaacatggg cttagttggt ctgatgctgt cttcttatgt
      901 tttgctggtt ggcggtcagt taaatggacc tgtcatcggt gctattttat ctgcggtggg
      961 tttcagtgct tttggttgtc atttaaaaaa cagttttccg atactagtcg gaatatttat
     1021 tgcttctttg tttggaactt ttcatgagat caccagtact ggcatgcttg ttgcagctgt
     1081 gtttgggaca ggtcttgcgc ccataagcgg tttttacggc agtttttacg gtgtaatagc
     1141 tggtgtgcta catattgctc ttgtccataa cgtcagcact ttgcacggag gactaaatct
     1201 atataacagt ggtttttcaa ctggtttcgt tgcaggtatc cttgtaccga tactagataa
     1261 ctttaccgct gtcagaaagg aaaaaaagac acttggaaaa agaattatca aaaagaatca
     1321 tcgatgagct tcttacttat ttatattccc atgaaataac tgaaatacgt attggagtag
     1381 aatttgctga ggaagggctt ttcatagaga tacagggtac ggcagaaact cagccagaag
     1441 atttagatgt acttgctgat ttgctgaaca atcctcggga ccctagtatg gaaatctact
     1501 atcaagaact attaggtaat ccccgacatg atcgggaaga ttatcatctg ttaggtagtt
     1561 tgattgatga cgtggaaatc atgtatgccc agccgattat caatattaag atctttcgac
     1621 gtgcttctca ttcctattat taaccctatt ttctatttat aaaagactga atcaaaaaag
     1681 cagctcctga aagttcgatt aaaatctact ttcaggagct gttcaagctt gacattattg
     1741 attttccaat ccttcataca cttcatctgt tacaggttct aaaaactctg aattaccagc
     1801 agtgatcgcc aaatgttcaa accaactgtc ttttgtcgca ccatgccaat gtttaatccc
     1861 tttgtgcgtt acgacgacat ctccagccat taatcgtctt gctggctttc cttcttcctg
     1921 ataccagcct tctcctccgg tcacaagtaa gatttgatag ccgtctgtat ggacatgcca
     1981 gtgattgcga caacctggtt caaaagttac attacctaca ccaacagaaa cttcgggatc
     2041 attcactaac atattcagat agctttgccc ggtaaatact tgagcgtaag cttcgttttt
     2101 ttcacctgct ggaaaaatca cgccattgtg tatttcttcg tgttttgtca tcatttacgc
     2161 ctctttctta tcttcgctat tttcttctaa atagatttct tttgctaaac taaaagctga
     2221 ccaagctttt ggccattcta cataaaaagc taaatgggta atgatttctg ctatttcttc
     2281 actagtaatg ccattttgct tgccaatctt cagatgagct ggcaattgtt caaaatttcc
     2341 tcctgaaatt aatgcagata tggtgatgat actacgctga tgagcagata attcttctct
     2401 ggaccatact tgtccaaata aaacatcatc atttaattct gcaaattttg gtgcaaaatc
     2461 tcctaattga tctcgtcctg cggtttgttt ttctgccatt tctcttattc tcccttcacg
     2521 actgttaggt gattcaacta tggttctaag gcaactttat tttctattgt ttcttcgcat
     2581 ttcattttaa atgtagtctt tcagcctgtc caatgcttag tttattcagt cgatatgctt
     2641 tttaagcata gttgctaacg ctttttttat tttaaaaaaa acaagttatt aaataagtct
     2701 ttagttggat gtttttttga gatcaat
//
LOCUS       DAZAOD010000174         2677 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000174 DAZAOD010000000
VERSION     DAZAOD010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.178"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            701..787
                     /locus_tag="ACHDPO_002865"
     CDS             701..787
                     /locus_tag="ACHDPO_002865"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFN3370419.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1089..1313)
                     /locus_tag="ACHDPO_002866"
     CDS             complement(1089..1313)
                     /locus_tag="ACHDPO_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370420.1"
                     /translation="MEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNMTPERKRS
                     LEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1679..1963
                     /locus_tag="ACHDPO_002867"
     CDS             1679..1963
                     /locus_tag="ACHDPO_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370421.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1966..2382
                     /locus_tag="ACHDPO_002868"
     CDS             1966..2382
                     /locus_tag="ACHDPO_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370422.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(2519..>2677)
                     /locus_tag="ACHDPO_002869"
     CDS             complement(2519..>2677)
                     /locus_tag="ACHDPO_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFN3370423.1"
                     /translation="NPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTSDLPKI
                     SLRNWLEE"
BASE COUNT          882 a          498 c          430 g          867 t
ORIGIN      
        1 tccgtttttt catccattcc tttcttcccc ccttacaaat aaataataac ctttaacaac
       61 caactcgtaa ataggttggt tgttattata caaaaggata ttagtactca gataaaaagt
      121 tgttagtact cagataaaaa gttgttagta ctcagataaa aagttgttag tactcagata
      181 aaaagttgtt agtactcaga taaaaagttg ttagtaccct tctgtatccg ttgggagagt
      241 aaggctcaac tgccccctaa aaagggttct aaaaaatctt taaaaaataa ataaaataaa
      301 cgcgcgcgcg cgagcaaaat ttcccgccaa aaaatcaccc actttttaaa ataaacaggt
      361 tcgcgcatga tattaaactg ccaatctagc tccctatggt cgctgtaaga aggagtgatc
      421 gctacgctct cacattttac ttgcagcagt cgcctttagg ctccttcgcc aaaaataatt
      481 cattagggac tcctttgtgg cgtcctgaga gctcgtctaa gccgttctaa gacaagattc
      541 gataaaaact atgtccttcg ttctaaagcg ccttacaggc ggtcagggca agccctaaca
      601 accccaaggc aataaaaaac ttaggcttat ttttgctttt ttattgtata attgattgtc
      661 gcctatccga cagtcttgcg actggaagga ggtgtgtttc gtgttcacta actttatttg
      721 ctcccttctt gttgggcttt taagcgcttt gttcagttac tggttgaata accgaaacaa
      781 gaagtaaaac ttaattaagg cgactcagcc cacaaaaaaa gccccagaga atccgacctc
      841 tctggggctt tcgtgtgttt cgtgttcact tatttgcaat caaattataa cagaaataaa
      901 tatttatttc aaaaatatcc tacaaaagtc taaaatccgt aattatttct tatatgcaac
      961 atttacaaat aaagtcgctc tgagagctcg tatttttcga tttaagacgt tttatttagt
     1021 ttttggtgta tttcattggt ccaagctaaa aaactcttag aagcgatttt agagccattt
     1081 aaacccactt aattatattc tccatgaaat tcgctccatg cgtcaaaagc tgcgtctgaa
     1141 attccgccgt cttcgttcac tagttgcatt aatttttcca acgatcgttt tctttcgggt
     1201 gtcatatttt tatattccaa caatttttcg tctgttaaat cgaacttgat tgcttgaatt
     1261 gcttgctcta atttttctaa gttttgaaaa tattcgtaag gaaatttttc cattttttct
     1321 ttctccagtc tcacaatttt tctagaaata aaatcacttc tttgccgtct atactctcaa
     1381 aaaaaatgtc gtttgaaaaa ctaaataaat ttttgatcgt gcatttttaa atttggttat
     1441 cgattacacg tgcagcactc ccccccgaat tttaaagagc ataaggaaac gtgtacccac
     1501 tttctaaaaa aagtgggtag ataggctgtg cctatcacgt ttctcagaaa aaaatttgat
     1561 atcacttttt cgccatcgtg ggtagcttat gtatagcatt ttggcaaaaa acagctatac
     1621 aaatatagta tttgtatggt atacataaat tatacataat tgcaaaagga gattttttat
     1681 ggacatttta gttcggaata ttgatccaaa gtttgttgca acaatagaca aacgttgcca
     1741 agaactcacg aataaaacag gagaaaaatg gagtcgaaat aaatatctaa aagttttaat
     1801 cgaaagtgat tttgaccgtc aacttacgac ttacaaaaaa gaccaattcg atttattgct
     1861 cgataaattt attgctatcc aaacagaaaa tactcaaata ttaagcgagt atgtctacac
     1921 aaataatcaa atcattgaaa tgcttatcgg aggaatgata taaccatgag aaaaacttct
     1981 gtccaaaaac atgttacttt gtaccctagt catgttgacg ttttagattc catcatcgaa
     2041 aaaaatccag atatcaataa ctactcggaa gccattcgct ttttatgtat gagttatgaa
     2101 cccgatacca acacgaccac taccagcaat caggcaaaac taaatgctat gggaaaagaa
     2161 atttccatca tgactgaaat catcgcagaa tttgctgatt tatatctaaa agatacaggc
     2221 gttcttattg gcacaaattc taaagtatat caagaagtga aagaaaaaat cgaagctaaa
     2281 ctaaatccat caaatcgaaa tcgaccaaag aatcatcaaa aagaaaccag tcaaacagtc
     2341 acttctagaa atttcgaccc aacaaatttt ctaaaacgat aaaaaacaga taggagttat
     2401 tcctatctgt tttttattta gaagccccat acaatatgct agaatgtact agcaatctta
     2461 gtcggttgta agggacttgt ctacttgctt aatgtaaggg gggcgagttc ttttttattt
     2521 attcttctaa ccagttacgc agagaaatct ttggcaaatc tgacgttagg cttgaaaaag
     2581 taaattctaa tttggcgatt ttattgccct tttttgcttt tatttttgtg actttaagat
     2641 cattgaagta tttttttagt tctcgtaatg caggatt
//
LOCUS       DAZAOD010000175         2503 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000175 DAZAOD010000000
VERSION     DAZAOD010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.180"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(944..1462)
                     /locus_tag="ACHDPO_002870"
     CDS             complement(944..1462)
                     /locus_tag="ACHDPO_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFN3370424.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            1829..2077
                     /locus_tag="ACHDPO_002871"
     CDS             1829..2077
                     /locus_tag="ACHDPO_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370425.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT          816 a          457 c          359 g          871 t
ORIGIN      
        1 taatcgcaaa tttaccccta tactactagt ttgtaagtta gattaataaa aatactaaag
       61 ttatttgttc ttttattaaa tacacctaca acttataaat tgatggtatt tagataacac
      121 gaaagaataa aaataacagc tgatagtaaa gtttgttgac gattgctact caatcgaaag
      181 tgagttagtg cgtatgaact tgcttctgaa aacttatgaa atgaaagacc ttttacatct
      241 tgcagaaatc gttactggga ttaaactaag caataaaaac taatgttccc ctcattcttt
      301 gaacttctac tatttgattt atttattctg ataaatgacg atttcacctt caggatcttc
      361 aaatcccgta tagaatttat ttaagatctc ttcagtatca gtaataggat aggcgatagg
      421 ccacataccc tttgatggtt agaataaact gctcaaaatc tgtatcgtat gttggcttta
      481 gcatattaac aaaggctatc tccaaattat aaaccataag cgttgaatcg ttcttaacaa
      541 tttcaattct tcctaaccca aagtcagaag atataattac cggacttgcc ttacccttca
      601 tgtgggttgt tgagattcca tatttaaagg gaattgtcgg tactatcggc ggtctgaaaa
      661 acatcccaaa aataaaaaaa tctttcccct gctagtctcc taagtccctt tgtagcggat
      721 atggcaccat aatctcattt tatcgaagtg agtcatggtt tatctgttgg ccaaccaaaa
      781 ttgatacaat ctaacgatgc accctctacg gcattctagg ggagtgcact tgcattcacc
      841 caataaaaac cggcagttag caaagaactt atgtagtcgt atgttcttac tgttaacata
      901 caagaggtct cctttccaca attgcttagc agtaaacggg aatttacaaa gctaatctct
      961 tccattttct tatctttgtt ctaaaagtcc caaatggagc aactgtattt acatgaataa
     1021 atttatatac ttcccataca gccgttttgg ttgcctcgtc tgcccatttt cttttgtgtg
     1081 cagtgaatag atcttcatca ctcattgaat caatcatcat gttaatatca tcaatattac
     1141 gattgagaat ttcctctaat tctttcaatg gtagatgtgc ataggtattt gtaaaccact
     1201 tatataactc tcctaactga ttccatttaa attgatcaga aggcgtttta acagataatc
     1261 catttctttc atcattttcc cattttagaa ttaaattcgt ccaaccaact tgatatgcta
     1321 aattttcagc aggtgttcta tccacttcct caactctttt atccttcaat tcttcaggaa
     1381 tagtttcaaa ttctaaaata tatttagtat aagtcctatt tatttctttt tttaattctt
     1441 ctttattttt atatgttctc attatattac ctccataaat tcctaattgt ctcctttaat
     1501 tcatctataa tttcatccac gatattttaa tccgttctac aatgcatatc tgatatgcat
     1561 tgactgtcta actcatatgt gaatgattta taaaatatcc caacgtctca tctaaagaaa
     1621 tgttgatcgt cagcaaggag ctaaaaaata cgaatatatt tcttttgtag taaaatcgga
     1681 ctggtttgca tatcattttc ttcgtaaata tcaaaatcat gttaactact atcaattact
     1741 aataaaaact accactttaa gcgttaagaa ctgttaagtt tagttaagtg aggatagttc
     1801 acaaaatcca ttgttaaact tcacgaaagt ggtaaaactc aaaatgcttt atataggatt
     1861 acagcatcgc tctttcttcg attgcgcgtt gggtaaaaaa tattatgaag taaaaattga
     1921 cgatgacacg ttccttacgg ctcatcagat gaaacagcta caaaaacgaa atgatcaact
     1981 cgaagaaaat ttaattctaa aaaagcgatt gccatattca cgcctcgctc gacgaactat
     2041 taaaggtcaa gatttacctg aagatcatcc tttttaggaa attgaagctt tttatgttgc
     2101 acaatgcatt tataatacta caatgatgtt ttcaccagat attcttctag ggtgcggtgt
     2161 aatgaaacag atacacttgc aaaagaaaat tcaccgcgaa tttactaaaa ttatgaataa
     2221 ttatgttaat cttccgaaat ttttttccaa aattaaggga tcaagctggt gttatagatt
     2281 gtttaaggtt ggcaaaaaaa taacttcttt ttaaacaatt atagaaaacc gatactctgt
     2341 taagttggtt gacacggtgt cgatttttat gactttctta ttctgaaact tcactaacgg
     2401 acagtaccta aaaagtctat agtatggacg tttacgagta ctattttatc aaaaatgctg
     2461 ctcatttcaa cttatatgtt ttagtgaact acccccactt agc
//
LOCUS       DAZAOD010000176         2400 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000176 DAZAOD010000000
VERSION     DAZAOD010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.181"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            207..2069
                     /locus_tag="ACHDPO_002872"
     CDS             207..2069
                     /locus_tag="ACHDPO_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFN3370426.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="ACHDPO_002873"
     CDS             2069..>2400
                     /locus_tag="ACHDPO_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFN3370427.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DAZAOD010000177         2326 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000177 DAZAOD010000000
VERSION     DAZAOD010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.182"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(296..903)
                     /locus_tag="ACHDPO_002874"
                     /pseudo
     CDS             complement(296..903)
                     /locus_tag="ACHDPO_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            1426..2100
                     /locus_tag="ACHDPO_002875"
                     /pseudo
     CDS             1426..2100
                     /locus_tag="ACHDPO_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            2093..2254
                     /locus_tag="ACHDPO_002876"
     CDS             2093..2254
                     /locus_tag="ACHDPO_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370428.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
BASE COUNT          826 a          374 c          408 g          718 t
ORIGIN      
        1 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
       61 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      121 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac
      181 tgttgccatt ccatctatga atataaatag agtgtatctt ctttgataaa tgtcagaaaa
      241 agtgtgacaa ataaccatca gtaaaattac ttgtcatact attgataagg agtatttaat
      301 tgaagagaat gattaggaga aaggatctcc gtacttttta tagtaatcat agaatccaag
      361 tttgtataga cgaatctttt tttctcttat ttcttctgtt tcaaaatgga ctgcttgaag
      421 aatcaagtct gtgaattcta taggagctgt tccattcgca gtaatcaaat tacgatcttt
      481 cacagcttgt tgttctataa aatcttcttt attctgataa ttttccgatt ctaaccaagg
      541 aaattgcgca tttccggtgt gtttgtaacc ttgcaataat ccgctctgag ctaaataatc
      601 aactgcccca caaatagcag ctactggtac gtctgttttt aacaatttat cgattatttg
      661 atataaatga tgatttttta tgtcccatga attgccaccg atcataataa aaaggtcaac
      721 tttttcaggt atttgttcga ttaagtaatc gatttttgtt tttaatcctc caatggaagt
      781 gacctctgat tggatagaag cagttttgtt ttgccatccc tctttttggt ttagtgtgct
      841 agtaatataa gcaccttccc aatcggcata ttcctctaat agaaacgtaa tcgcagtttt
      901 cattttcaag ctctccttta ctatctatga caaggacaac agttttaaca tacagacatt
      961 cattaaattt ggatagcgac agcgaaaaca acaattctta agttttagac agagtataca
     1021 gacagtcaac ttaattaaat acgaactaaa taaaaatgac aggtaatcat ttttgtttac
     1081 cagcattata acattttgca tacatggatg acaaaagaac caattcccac ttgcttgagt
     1141 acaatcttaa aagaaactgg aaggcaaaaa gtaattatag aaacgaaaaa taaatcatat
     1201 cgggcactca gacatgaaaa caaccctaga aatatataac tagtccaatg aaaaaaaagc
     1261 gaatgccgta gaaaacaagg attctgcgta cattcatatc tcattttgcg agcatatctg
     1321 ctattactgt gactaaatgt taatatggtt aaaatgaccg ttatattttt tatataaata
     1381 tcgtataatt agtatgaata tagaagaagg aaagaaggtg caatcttgga acctaaagac
     1441 aagtatttag attacgctag ggtcaataaa gataaattta ttgaaacaat catcaaggga
     1501 aaaatccctg atgatgaaaa agatgcggta ttcatggctg gaagcccagg agcaggtaaa
     1561 acagaggttg cactaggttt agcttaaaat tatgacaacc atgttgtgat tgatgcggac
     1621 tattttagag cacaatttcc agaatacaat ggaaagaact caagtgtttt tcagaaagct
     1681 tcttcttggt tagttgaaca atcattaaaa tatgtactgg aacatggcta ttctttcata
     1741 ctagaggata cttttgctat ccttagtgca gagaaaaata ttattcgagc ccttaaaaat
     1801 aactttcgcg ttacgatttt ctatgtttac caagatccca aagttgcctg ggatttcact
     1861 cgaaaacgtg aactagctga aggacgtcat gtgccaaaag aaatgtttat caatgcgttt
     1921 tttaagtcca gagagaatat tgaaaaagtc aaaaatagac atcctgaagt agtccttcac
     1981 ataatgatta aggattatca aaacgacatt tctgaagtgc attatgcagc agataatatt
     2041 caattagtac taccaataca atatacttca aaagagttgg aggaggaatt acatgactga
     2101 gaaagaacaa gtacaacaaa tcgtgaagaa gtataataaa agtatcgctg atttatcaga
     2161 aaacgcctca gcgaaagaat ttaaaacagt aatgaattac gtagcagatg aagcaaatcg
     2221 taagcagcga aaactagttg ggttggataa ataaattttt taaaccatat ccttgtaaag
     2281 ttgagttttt tattttaatg aattaagact attaaataga taatta
//
LOCUS       DAZAOD010000178         2313 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000178 DAZAOD010000000
VERSION     DAZAOD010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.183"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            191..445
                     /locus_tag="ACHDPO_002877"
     CDS             191..445
                     /locus_tag="ACHDPO_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFN3370429.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="ACHDPO_002878"
     CDS             446..763
                     /locus_tag="ACHDPO_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFN3370430.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="ACHDPO_002879"
     CDS             1322..2257
                     /locus_tag="ACHDPO_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370431.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          846 a          313 c          434 g          720 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag aaaaatgtct
     2281 aaacatgttg gtaaatcaac aaaaaaacgc ata
//
LOCUS       DAZAOD010000179         2305 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000179 DAZAOD010000000
VERSION     DAZAOD010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.184"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..2155
                     /locus_tag="ACHDPO_002880"
     CDS             2..2155
                     /locus_tag="ACHDPO_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFN3370432.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          790 a          413 c          511 g          591 t
ORIGIN      
        1 aatgatgaaa gattttatga aaaaaatatt aaatacttct tggttagaaa aaataagaaa
       61 aggtgcacaa gaacctaaga acaaaacgtt tcgccggtcc catgttcctt ttcgcttaaa
      121 ttttcttttt ttcattatat ttacgttatt tgttgcgttg attgctagat tgggttattt
      181 gcagatcgtg aacggcgaag agatggaggc gcgagtgaag tctacttcta cgattacggt
      241 ccaagaaagt actcctcgcg gaatgatcta cgactccaca ggaaaagctt tagttacgaa
      301 taaagcgaat caggccatca catatacgag aggaacacaa gttacggcta aagatttgct
      361 tgaaatcgca acgaagctga actcgctgat cgatgttccg gtagatgaaa atctgacaga
      421 tagagataaa aaagattttt ggctggctga tcccaaacat ttgaaagaag ccacaaaaag
      481 actttcggca aaagaaaagc aattagggaa cagcgaacaa tatagtgcga tggtcaataa
      541 agtcacagct gatgagatta atttaaacga ggagcaatta aaaattgcta ccatctttaa
      601 acggatgaat agtgcatatg aattaaacac tgtctatatc aaaaactctg gtgttactga
      661 tcaagagtta gctgttgtgg cagaacgcgc ttctgaactt ccaggagttt cgactggcac
      721 agactggaca cgagaatata atgcagcaag ttcactgaaa agtattcttg gcagtgtgac
      781 gactgaaaag caaggacttc cagcagatga agcagagaaa tacctagcaa aaggttattc
      841 tcggaatgac cgtgtaggac aaagttattt ggaaaaacaa tatgaagatg tcctgcaagg
      901 aaccaaaacc caatatgaag tttcccttga taatgaagga aatgtttcga atcaaaaaga
      961 aatcttctct ggggaaaaag gttctaattt aatgttatct atgaatgcag aattccaatc
     1021 aaaagtagaa gaaattttga aaaggaatta tcaaacattg atcaacaacg gcaaagcaca
     1081 gtattcgcct ggtgcttatg cagtggctat gaatcctcag acaggagaag tgctagcaat
     1141 gactggtttc agtcatgaac aaggttccaa agaaatcacc gagaatgctt taggcacgat
     1201 tactagcgcc tttgatccag ggtctgtagt caaggctggt actttgacag caggctgggc
     1261 aagtaacgcg atcagcggaa atcaagtttt gattgatgag ccgattcgtc tgcaaggtgc
     1321 ttcagaaaaa agctctgtct ttaatcgaag cggacaagtt gctcttgatg cagtcaaagc
     1381 atcggaattg tcttctaata cgtatatgat caaagtggcg ttaaagatgt taggactaga
     1441 ctatacacct ggaatgggac tacctagttt agatgaagaa gctaaagctt atcagcaatt
     1501 gagagactct ttcaaagagt ttggtcttgg tacaacgact gggatcgatt tgccgaatga
     1561 atctcctggg atctcacgtt ctgttgatta tatgaagaag ttcaatgcgg ataatggcaa
     1621 agaatggtat gctccaggta actttaccga tttggcattt ggacagtttg acacatatac
     1681 accaatccaa ttagctcaat atgcttcaac agtcgctaat ggcgggaaac gagtacagcc
     1741 gcacctagtc aaagcgatct atggcaatga cgaaaatgga aacttgggtg aagtgaagaa
     1801 agaaattggc acaacagtag aaaatacggt caatatttct gcagaaaata tggcgatcct
     1861 ccgtgaagga ttccaccaag ttgtccatgg taccgatcct tacacaacag ccaaaccatt
     1921 agccagtgcg aaaatggacc tttccgcaaa aacagggact gcagaaacgg ttgcggaagg
     1981 tcatccagat attgcgacag tcaatagtaa tatcgtggca tacggaccaa cagacaatcc
     2041 ggaaattgcc atcagtgttg tcttgccgaa cttattagac gaacaagacc acataaactt
     2101 gacgattgct aaagaaataa tggacgcgta ttatgatatg ttcatggcaa aataaaaaag
     2161 aggtcgtgaa aaagccgctt agtttcgagt atgaagaaaa attttgtgaa aatagcttct
     2221 cacatttttg cttaaatttg acttcatacc gagaaactgg cttttgaaca ccgtttactc
     2281 ggcaaaaaag gttgtgacaa aaatt
//
LOCUS       DAZAOD010000180         2271 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000180 DAZAOD010000000
VERSION     DAZAOD010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.185"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            7..525
                     /locus_tag="ACHDPO_002881"
     CDS             7..525
                     /locus_tag="ACHDPO_002881"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFN3370433.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            653..1336
                     /locus_tag="ACHDPO_002882"
     CDS             653..1336
                     /locus_tag="ACHDPO_002882"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFN3370434.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1645..1718
                     /locus_tag="ACHDPO_002883"
     tRNA            1645..1718
                     /locus_tag="ACHDPO_002883"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1679..1681,aa:Arg,seq:tct)
     gene            1877..2236
                     /locus_tag="ACHDPO_002884"
     CDS             1877..2236
                     /locus_tag="ACHDPO_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFN3370435.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
BASE COUNT          762 a          353 c          455 g          701 t
ORIGIN      
        1 aaaacgatac ctgattacaa aaaaataact tttataagtt ctataacgtt gattatattt
       61 ttaattctta ttcttctcgt cgtcttggtt ccccgaattt ttggtttgac tccttatatt
      121 attgaggaca aagaaatgag tccatattat gcacaaggaa atctgatata tgtacgaccg
      181 aaaaatacaa atgagatttt agtcggagat attattacat attatgaaaa ttcaggaaaa
      241 aaaatctcga cgcgtcgcgt aatagccgtt gaaaacaacc acgaagattt ttatacaaaa
      301 gctgatacaa agacttatat tgagcctgga gtagtaaaaa agagaaatat tatcggtagt
      361 cccatctttc agattccata tattggacta gtcctttcaa aaacggcatt tgcatggatt
      421 caggggttat tctttacgat tgctttttgc ctaacaggaa tcacagcatg gaataccttt
      481 gtagagttga aaaagaagcg gagacgaaca cagaaatttt tgtaagaatg ttaaaaacat
      541 aaatgtattc cagagatcca acgactcttc tgaacatgaa acacgagaaa acactcatgc
      601 agcttgtaga tttagtcagt tgttcgtata atgtgtgaag aggaggagta gtatgcgcaa
      661 tgaaatgatg catcgtcctg tagtcaaaga agaactattg gattttatgc gtacccagca
      721 aaaaaaatta ccgggtgagc taggcaaact ggaagaagaa gctcatgtag cagaagtacc
      781 agttattccc catgaaacag ttgtattttt gaaattttta cttggacagc ttcagcctga
      841 acgaatcttg gagatcggag cagctatcgg tttttcatca agtgtcatgg ccacgacaat
      901 cggagaaaac gctcatgtta cgacaattga tcgtttcgat gtcatgatcg agaaagctaa
      961 aaaaaactat gaacgtctag gactgacaga taaagtgact ttgcttgaag gtcaagcagc
     1021 agatatcttg ccggagttgt ctggtccgta tgactttatt tttatggata gtgcaaaatc
     1081 aaaatatatt gaatttttac ctgaatgctt acgtttgtta agaaaaggtg gcgttttgat
     1141 ggtagatgac atcttccaag gaggaacgat cttgctccca gatgaagaga ttccccgtgg
     1201 caaacgagct atccatcgta aattaaatga atttcttcgt gttgtgatgg atcatcccga
     1261 tttgacatcg acaatcttgc cattaggtga tggtgtgatc ttaatgacaa aggaatcaga
     1321 aacaatcgag ttgtgataca tgattatggc agcctgtaga taatcgattg aatcgagggc
     1381 tcaattcgaa cttgatgtaa aagtttctat atttgtaagt caattaaagg atacaggaaa
     1441 tctaaataaa caggagtagc atgaagtcaa tgtagctcct gttttcaatt gataacctta
     1501 gaacagctga aggagaatgt ctcgttttaa aagattgatt tagtagttgg gccaaaataa
     1561 ttcattattt gctaattaaa taactatttc gtattgacag aagcaattta attatctata
     1621 attattgatg ttccgctgat tcttgtcata gtagctcagc tggatagagc atccgccttc
     1681 taagcggacg gtcgggggtt cgaatccctc ctgtgacgct aaaaaaccgt tagaaactga
     1741 ggtttctaac ggtttttctt tgttttttgt gccaatattg tttgttttca aaggcaaata
     1801 aaataaaaaa acatccttat cgagtacaat tataaggagc aaaaaaataa aactcatcag
     1861 aaaagaggaa gaagatatga cgatactatc tagaatttta gtgactctag ttgcaattga
     1921 atttttttat atcatgtata tcgaaacggt gagaactgat tctgacacga caagtagggt
     1981 ttttaaaatg agtaaagaag agttaagcag aaaatctgtt caaacattgt ttaagaacca
     2041 aggagtgtac aatggactat taggagtggg actactttat ggagcttatc tttcttccgc
     2101 atctaaagaa atcacaagta tgctattaat atctattttt tttgttgcat tatatggcag
     2161 tttgactagc gatcgttgga ttttactcaa acaaggtggg ctagctctgt tggcattgct
     2221 ttctattttc ttataaatat agaaaaaata agaatttatc taacaggaaa c
//
LOCUS       DAZAOD010000181         2267 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000181 DAZAOD010000000
VERSION     DAZAOD010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.186"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="ACHDPO_002885"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="ACHDPO_002885"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFN3370436.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="ACHDPO_002886"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="ACHDPO_002886"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFN3370437.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
BASE COUNT          825 a          362 c          477 g          603 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagccca
//
LOCUS       DAZAOD010000182         2249 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000182 DAZAOD010000000
VERSION     DAZAOD010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.187"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            140..>2249
                     /gene="acm"
                     /locus_tag="ACHDPO_002887"
     CDS             140..>2249
                     /gene="acm"
                     /locus_tag="ACHDPO_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFN3370438.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIG"
BASE COUNT          884 a          345 c          441 g          579 t
ORIGIN      
        1 tttttataaa tatttgtaaa ataactatca attttttagt taaaagattg gaaatgagtg
       61 ggggaggaat tgaagaaagg atttttgaga gatgatatag taggttttat ttttagttaa
      121 aataggggag atagaaaaaa tgaaaaagtg tagaaatatt attttatcaa tgttatttat
      181 tattactaat ataacatcac tgattcctgt tcatgtctat gcggatgcag gcagagatat
      241 cagcagtaat gtcacttcgt tgaccgtgga cccaacgaat attacagatg gaggaaacat
      301 aaaagtaaaa ttctcgtttg acgaaaaaaa acaaaatatc caaccaggtg attatctttg
      361 gatcaattgg ccaagtgaag gaaatattcg cggtgaagga ttccaaaaag aaatcccatt
      421 aatgattgaa aataaaaatg ttggaacttt aacggtcaga aaagattctg cgcaggttgt
      481 gtttaatgaa aatattaaaa acctagactc agtagaaggt tgggggcaat ttgagataca
      541 ggccagaaac gtaaccgata ccggtgaaga aaatacggga ccattcaccg tgacgagcgg
      601 tgataaaaca gctactgtaa atgtgacaaa gccagcttct ggttcttctt ctagcgtttt
      661 ttattataaa acaggagaca tgctacctga agatactaag cacattcgat ggtttttgaa
      721 tattaacaat aacggcactt atgttgaaca accagttaaa atcagtgatg aaatccaaag
      781 tggacaaaga ttagatccaa gtacgtttga aattaatcaa atacacttag gtgaacagaa
      841 ggtttataga ggagaagagg gaatccaaca atttttacaa gatttcccca gcgctacatt
      901 taatttttca gtaactgata attacattga aataactata ccaaaaaact ttgtcaatct
      961 taggaaaata atggtgagtt ataagacgat catagaaaac ccagaacaaa taaattttga
     1021 gaatcattcg gaagcttggt ttaaagaatt taataaacct gctgttgatg gagaaagttt
     1081 caatcataca gttaaaaata tttcagcttc tggtggagtc aacggtacag ttagaggcga
     1141 attgaagatt ttcaaatata tcaatgacac agagattggt atcccaaatg tgactttcga
     1201 attaagacga gcagatgaac agcctattca aggacagtct agtatcctgt tgacttcgaa
     1261 tgaacaggga gaagctagta tcaaaggcct gcaagtagga gactatgttg taaaagaaaa
     1321 agaagcaccc aattggattg attttgatcc actaagttca aatgaactca aattctccat
     1381 aaacgaaaat gatacagagg gagtcagttt acctatttat aacaagaaaa aggttacgaa
     1441 catcacagca actaaaattt ggaacggtgg aaccactcca agaccgagta tttattttaa
     1501 attattcaga gcaagtacaa acaattggga accagttcct gatgcagaaa caaaacgatt
     1561 agacaatgga ataacttcag tgacttggga agatatccaa cagtatgatg atagtggaaa
     1621 cgaatatacg tttaaagtgc aagaagtaga tcaaaacgga aatgattatg tcccttcagg
     1681 ttatcaaaaa attgaaaacg ggctagtcgt tacaaatgag aataaagaag tcatttcagt
     1741 ctcaggacaa aaaacatggg aagacaatga gaaccaagac ggcaaacgac cgacgacgat
     1801 cacagtaaat ctattagccg acggtcaacc gatccaacac aaagaagtaa gtgaaaaaga
     1861 tgattggcgc tatcgtttca caaatctgcc aaaatacaga gacgggcaag aaatcatcta
     1921 tactgtaacg gaagacaacg tgcccgaata cagtacgacg attgacgggt ataacatcaa
     1981 aaacagttat acaccggaaa aaacaaatat atctatacca ggtagccata taacaccgtg
     2041 gaaaaatttt ccagagaaga cagagagaga gaaaattaga aatctattct ctcaaaaatt
     2101 gcaaatattt gctcatacag gagaatccag cgaacaaaga agcaattata ttagtaagag
     2161 agctgtacct aaacagataa caaataaatc aaaaagcatt cttcctaaaa caagtagtaa
     2221 aaaatctagt tttgctgtaa tcattggtt
//
LOCUS       DAZAOD010000183         2193 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000183 DAZAOD010000000
VERSION     DAZAOD010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.188"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            40..603
                     /gene="ahpC"
                     /locus_tag="ACHDPO_002888"
     CDS             40..603
                     /gene="ahpC"
                     /locus_tag="ACHDPO_002888"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFN3370439.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            613..2142
                     /gene="ahpF"
                     /locus_tag="ACHDPO_002889"
     CDS             613..2142
                     /gene="ahpF"
                     /locus_tag="ACHDPO_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFN3370440.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
BASE COUNT          715 a          371 c          472 g          635 t
ORIGIN      
        1 aataattata aataaataat tattattgga ggttttacta tgtcattgat tgggaaaaaa
       61 atcgaagaat ttaatgcaca tgcttatcat caaggagaat ttttagaagt cagtgaaaaa
      121 gatcttatgg ggaactggag tattctttgc ttctatccag ctgattttac ttttgtttgt
      181 cctactgaat tagaagactt acaagaacaa tacagtacat tgaaatcttt aggtgttgaa
      241 gtcttttctt gctctaccga tacccacttt actcacaaag catggcatga tacatcagat
      301 gctatcggta aaatcgaata cgtgatgatc ggtgatccgt ctcatcagat ttctcgtatt
      361 tttgatgttt tggatgaaga gcaaggatta gctcagcgag gaacatttat tattgatcca
      421 gacggaatcg ttcaagctat ggaaatcaat gcagatggaa tcggtcgtga cgctagtgca
      481 ctgattgata agattcgcgc tgctcaatat gtacgtaccc acccaggtga agtttgtccg
      541 gcaaaatgga aagaaagtgg cgaaacattg aaaccaagtt ttgatcttgt tggaaagatt
      601 taggtggtgg atatgttaga caaagaaact aaacaaaatc tcgaacaata tttagcactg
      661 attgaatctc ctattgtttt ttctgttagt ttggataata gtgaaaatag tcaaaaacta
      721 gctgaattta cgaaggaaat agcagaaatg tctcctaaaa tctcttggga aaaaagagat
      781 tcgatgcgca cacctagttt ttctatcaat ccagttggca aagaaagtgg aatcgttttt
      841 gctggtatcc ccctcggtca tgaattttcc tcttttttac tggctatgtt acaaattagt
      901 ggacgggcac cgaaaatcag tgaatctttg agtcttaaaa tcaaaaaaat aacacaaaca
      961 ttgcattttg acagttatgt tagcttgact tgtcataatt gccccgacgt tgtacaggca
     1021 ttgaatatat tagctgtatt aaatccaaat attactcata cgatgattga aggtgggatg
     1081 ttccaaaaag aaatcgatga taaaaaaatc atggcagtgc caactgtgtt tttaaatgga
     1141 gaagaattta gtagcggacg catgacgatc gaacaaattg ttgaaaaaat cactggccct
     1201 ttgattgaag aagagttgtt tgaaaaagaa ccttatgatg tattagtgat tggcggtgga
     1261 ccagcagcta gtagtgcagc tatctatgca gcacgtaaag gaatccgtac aggacttgtc
     1321 gctgattctt tcggcggaca agtcgttgaa acactaggga ttgaaaatat gattggtacc
     1381 tcttacacag aaggtccaaa attgatgcag caagtagaaa gtcatgtgcg tagttaccct
     1441 atcgacatta tgatgaatca acaggccgtt tccttaaata aagagcaaca ttttattaat
     1501 attggcttag ctaacggtat atcacttaaa gcaaaaaccg ccatcatcgc gacaggtgcg
     1561 cactggcgtt ctatcaatgt accaggcgaa aaagagttta aaaataaagg aattgcttat
     1621 tgcccacact gtgacggccc tttatttaaa ggaaaagaga ttgctgttat cggtggtggt
     1681 aattctggtg ttgaagcagc aatcgatttg gctgggttag caaaacatgt atatgttcta
     1741 gaattcttac cagaattaaa agcagatcaa atcttacagg ataaactagt ctctcttgcg
     1801 aatgtcactg ttatcaaaca tgcagcgacg aaagaaatca gcggtacgaa tcaggtagaa
     1861 tctctctcct atatcgatcg ccgtacgatg gagatgcata cactagctgt ttcaggagta
     1921 ttcattctag tcggcttact ccctaatacg gattggctag atggaacgat cgaaatgaat
     1981 ccaagaaatg aaatagtgac cgagaaaaat ggcgcaacga atatccccgg cgttttcgca
     2041 gctggtgatt gtacagatag tccatacaaa caaatcattg tttcaatggg ttcaggagct
     2101 actgcagctt taggagcatt cgattatctg atgcgcactt gagctatgaa gattgtaaaa
     2161 agtcagagag cggaaaaaag gatggtgaca aga
//
LOCUS       DAZAOD010000184         2189 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000184 DAZAOD010000000
VERSION     DAZAOD010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.189"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(346..528)
                     /locus_tag="ACHDPO_002890"
                     /pseudo
     CDS             complement(346..528)
                     /locus_tag="ACHDPO_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(987..1952)
                     /locus_tag="ACHDPO_002891"
     CDS             complement(987..1952)
                     /locus_tag="ACHDPO_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFN3370441.1"
                     /translation="MSKRGTIINEWENLTALSNRRLSVQTLTTPLKIQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRLNENNGYVKSVGLNGWQIVDKHDENIAYIEILKY
                     QEGQGRIDFNPNKISQFLAGSMKNFIHDLFLEPHFSRADIACDIIDVPDDFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQETKRKIVPPEIKTWWRLELQ
                     LRRGKATDWYAMVHESLDSFASPHFLPTDTKHTDRIMIAGLISDQNLWAGLARHTKYK
                     YRNLLKKESQSDELVNHLRETFSESADVLKKELDTWLLGLDVTEE"
BASE COUNT          629 a          506 c          346 g          708 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggctttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cgcgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaacgct ctccgagggt tttcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat aatcgcttat
      661 cttaaacatt gacgtaaatt tactctcact tatctgactt ttttactcgg tatcactccg
      721 agtaagccgt catattcatt gggataatct cgtctgcttc gctctaattt tccagagtga
      781 ggggtaactc cttcccccga attaccccaa agagtgacac tgggatatcc ctaaatttat
      841 tataaaaagc caagtctctt tgcgcaactg ttttatccaa gtcggcattt gcggattcgt
      901 tagcgttttt tcgctcttgc tgcaaacgca cgacccacca tgccgacttg tgctgaaaat
      961 aaaaaagtgg acaaaaattc atccactcat tcttccgtca cgtccaaccc caaaagccac
     1021 gtatccaatt cttttttcaa aacatctgcc gattccgaaa atgtctctcg taaatgatta
     1081 actaactcat cactttggct ttcttttttc aacaaatttc gatatttata ttttgtatga
     1141 cgagccaagc cagcccataa attttgatct gaaatcaatc ctgcaatcat aattctatca
     1201 gtatgctttg tatcagtcgg caaaaaatga ggacttgcga aactgtctaa actttcatga
     1261 accatcgcat accaatcagt agcttttcca cgccgtaact gcaattccag tcgccaccaa
     1321 gtttttattt ccggtggtac aattttccgt ttggtttctt gttccaattt tttgttgtac
     1381 atccttattt gtcgctcact ggcacgacta ccccaatatg ccgtttccag cttcccagac
     1441 cgcccataga ttggtttgaa tgaaacaggg tcaaccacac gatattgcgt aataaaatca
     1501 tcaggcacat cgataatgtc gcaagcaata tcagcacgtg agaaatgtgg ttctaaaaat
     1561 aaatcatgga taaagttctt catcgaaccc gccaaaaatt ggctaatttt atttgggtta
     1621 aagtcaattc gcccttgccc ttcttgatat ttcaaaattt caatgtaagc aatattctca
     1681 tcatgcttat ccacaatttg ccaaccattt agaccaacag atttaacata accattattt
     1741 tcattcagtc gcattaactg ttcaaagtct aaaatcaata catcattttg cgtgtgataa
     1801 taaatattct ctttgagttt tccaacaatg gtaattcggt caattgacca ctgtatttta
     1861 aggggggtgg tcaaagtttg cacacttaac cgcctgttag atagggctgt taaattttcc
     1921 cactcattta tgatcgtgcc acgtttactc aaattttgtt cctcctcaaa gaaaaagaga
     1981 cttttggaaa gaatttccag agttcacgta accctaaaaa ttcatatcca aaaatctcta
     2041 gcttgaagaa acctaaaaat attcgtataa tgaacctgag ttacggagct aggtgaagta
     2101 gtttccgtaa atagtcgaga gtgttagcgc actgctcggc ttttattttg ctcttttttc
     2161 tcgttttctt tgattatagc actcctcct
//
LOCUS       DAZAOD010000185         2184 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000185 DAZAOD010000000
VERSION     DAZAOD010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.190"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(63..353)
                     /locus_tag="ACHDPO_002892"
     CDS             complement(63..353)
                     /locus_tag="ACHDPO_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370442.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(471..731)
                     /locus_tag="ACHDPO_002893"
     CDS             complement(471..731)
                     /locus_tag="ACHDPO_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370443.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(868..1281)
                     /locus_tag="ACHDPO_002894"
     CDS             complement(868..1281)
                     /locus_tag="ACHDPO_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFN3370444.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1737..2183)
                     /locus_tag="ACHDPO_002895"
     CDS             complement(1737..2183)
                     /locus_tag="ACHDPO_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370445.1"
                     /translation="MLFSACGYKTKNSVKESSAAISTTEVGSTKSTSTTSITNTSTGN
                     VDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHRSELQSDDIVISFY
                     QKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTPF"
BASE COUNT          798 a          354 c          348 g          684 t
ORIGIN      
        1 cacccaactt tcaaaaatat gttttggaag ttgggacaaa cgagttaata cattttaata
       61 cattattttt tattcaaaaa aaatagcaca atggcaaaga tcgtaagaga gatcataagc
      121 cccaatgaat gactaaaaag aaaagcagaa tcacatgcca tatcatccca tatttcttca
      181 agaaaataaa taagcgggaa aaagggaagg aatagtagaa catcgatcca gcaccatttt
      241 tttcttcttt tgaaataaca taaaacaata aacatgaacg tgcagggaag taaaaacaaa
      301 gctttactca taactaacaa aataccagct ccttttattt ttttctcccc cacattcaaa
      361 gagtaacaat ggtatgtact taataataga aaaatggatc aacttgtatg aataacagct
      421 gaaaagatct gcaccaaata aaaaacttcc agccaaaact gactggaagt ttattttttt
      481 ctgaaatatt ctaacacaaa tatgaaaaag atggccgaag ctaataagcc gatttcgtag
      541 caaaacaatg agataccaga gtcgtaataa taaaatcctc taatcttatg gataaaatag
      601 atcatcggac aagcagataa gagtaagtat ttgttaggcc ttttgaataa gtaaaagaaa
      661 gcactggtca ttatgataaa tggtatccaa aacaaaagtt tacttaagac aatcaaatga
      721 tcaactccca tattttttac caagagagat cataacatct ttatcgtaaa aacaaaatat
      781 ttttttgctc attttgaaaa tttaaacata ctcgttctta tccaaatata taaaaatcgc
      841 ccctcattca tcgagaggcg ataagttcta atttaactca attttttttg tttcttttgg
      901 ctgataagct gttttaggta ataccaattt cagcacaccg tttttaaagg ttccagtgat
      961 tttttcttca tcaacattag gaagatagaa tgaacgtttg taagagaccg aatgtctttc
     1021 tttccgtaca tagttgccat cttctttatc ttctgtatgg gactcatgat tggcggagat
     1081 cgtcaaagta ttatctgaat attcaactgt cgtgtcttct ttgtcacagc caggcatatc
     1141 agcagttagt ttgtattctt tttcattttc gactaaatct acttttggat aacttgaaac
     1201 acctaaaaaa tcattgaatg ctggactaaa cacgtcattg aaatcaggga acatgtcgcg
     1261 aatgctaggt acatttgcca tttttgatca tcctttcaat aagtattttt tatttatccc
     1321 tatttacgta ataactctat tttgaaaaaa atgcaagtat aatggttagc tttgtgaata
     1381 tttcatctaa tacgatacaa aggctatctt tctaatttga aaaagggatc attaaaataa
     1441 taagaagaaa atatgtcaaa aggtaaaaaa gtaaattctt ctatccaaat atagaaaaat
     1501 tgaatctaga aaaccgcccg acaataaatt tcattaactc agttgaccga aaatgaagta
     1561 gataccaaaa atttatcaag agagcaagta gagaagtgag tatattcata agagaaatag
     1621 ctgtaacgaa ttattaggtt aatgcaaatg cttatttata ctccgtataa ctttctcaga
     1681 aaaaatgata ccaataatga cttgctagta ctgtaaatcc gtataatatc atctaatcaa
     1741 aatggtgttc catttgcatc tgtcatcgta atcgatcctt cgggtgacac tcgataaaaa
     1801 ccaacgcttc cagatcctcc ttgggaacgg atttgtttgc tggaagctgt gaacaaataa
     1861 tctcgatcaa ttttttgata aaagctaata acaatatcgt cactttgtaa ttcggaacgg
     1921 tgggcaataa gaaatagaag tgctttgtca gagttttcta atggaagaga aggtacagtg
     1981 ctttcttgca tttcagatgt tgaagaaatg ctaaacgact gaatacttga ttggctatgt
     2041 tgcgaatcta cattaccagt agaagtatta gtaatggaag tagtagaagt acttttagtt
     2101 gaaccaacct cagttgttga aatggctgct gaagattctt taacagaatt ctttgtttta
     2161 tatccacagg cagaaaaaag tatt
//
LOCUS       DAZAOD010000186         2178 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000186 DAZAOD010000000
VERSION     DAZAOD010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.191"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            66..>2178
                     /locus_tag="ACHDPO_002896"
     CDS             66..>2178
                     /locus_tag="ACHDPO_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFN3370446.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSL"
BASE COUNT          800 a          285 c          405 g          688 t
ORIGIN      
        1 tagcaagtca tatttatgga aaaatactgt cggcaaaatt cgaatagtgt cgaggaggtg
       61 ctgtgatgga agaattaaaa gaacgcattg tcaattatgt catagagaac tctgagatta
      121 aaaataaatg ggggaacaat acagcacaga aaatatctga aaaattaaat gttagtcgta
      181 atattgtctc tcaatatttg aatgaattcg taaaagatgg agaatttgga aaaatcaata
      241 ctcgtccagt aatcttcttt tctttaccgg agaaagttcc aaatcaacaa atttttagct
      301 cttcagagga agcggaaaaa tggtatgata gctcttttag ggttggaata gaaagggtta
      361 tcggaagtca aggaagtctg cgaaatgtaa ttgctcaaat taaagcagca atctactatc
      421 cgccaaatgg cttacccatt ttacttcatg gcgagactgg aactggaaaa agctatttag
      481 caaattatgt gtataaggat ttgttggcca ataattatat agaagagaag gcatctttca
      541 tttcagttaa ttgtagtgaa tatgccaata atccagaact tttcttgtcc aatttttttg
      601 ggcatgtaaa aggtgcatat acaggagccg aagatggaag aaagggttta gcagaattag
      661 ctaataatgg agtcttattt ttagatgaaa ttcatgcatt gagcaatgaa tgtcaggaga
      721 aactttttca gtttatggat acgaggaaat ttcatcggat gggtgataat gaaaactggt
      781 acacatcaag ttgctggatt atatttgcaa catcagaacc acctgaggat aaactattat
      841 caactttgtt gagaagaata cctgtaaagc taacacttcc aacattagac agtcgttctc
      901 tttatgaaag aaaacagtta atcaagatat tttttaaatc agaagaagaa agactagcaa
      961 agaaaatact gatatctcaa caattattag attttttatt aaactatcgc tttagtgaaa
     1021 atgttggcaa tttgaaaaat atcattcaat tgacctgtgc caatgccttt tatttcttag
     1081 atgatttgga agaactttat attcagatgt atcatttacc acaatgggtg aatttcaacg
     1141 gcatgaaggt tatgaaaaga cagaatgaat taaaatatat tcaaatggat gatttggaaa
     1201 aagtagacga agtttttaat atcaacgaac ttatagagta tctttatcaa acgtggaaga
     1261 aagacactga taagcagcag ctttttgaga aatatgatag atattttaga caaaagaatg
     1321 ttgatatcca aaataattca gctttaacat atcccaccta tcaagagatt cgatttagac
     1381 agtatgttaa ggaaatagag agagattttc aaatagaatt tgactattat tatcttcaaa
     1441 taacgtctat ctttttgaat tcttggattt atcaaatcca attaacatcg gacgataaat
     1501 tatattcctt catcaatgat attaatagtt ggtgtagtcg agaagttcaa ttagtcaatc
     1561 gttttattca aataggggat atttatttaa caaaaattca aaaaaatgtt ttggttattt
     1621 tatttaagtt aatgtgtagt aaagaatttc agcaaaaacg tttagcactg attttggctc
     1681 atggagatct aacggcaacc tgtatagcaa gtactgctaa taggatcgtt gagagatata
     1741 tatacgacgc cattgatatg ccactaatga cttcaagtag tgagattgca gacaaaatta
     1801 atagatactt acaagagtgt accggatatg aagaaattat tttacttgtt gatatgggtt
     1861 cactggagaa aatttatcta aatttggaac tagacgctca aaaaaaattc ggactactaa
     1921 acaatgtttc aacaagaatg gctattgatg ttgcaaatca gatattatta gatttaccgc
     1981 ttaaacagat tcttgaacaa gtaaaagaaa atcaaaatgt ggattatatt tatgaatcat
     2041 caaatattaa gaaggatatg attgtctgtt cttgtgcaag cggattagga acttcgttta
     2101 aattaaaaag gatacttgaa gatagctttc caagggatac tgatcttgtc atagaaacgt
     2161 gtgactatta ctctttag
//
LOCUS       DAZAOD010000187         2095 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000187 DAZAOD010000000
VERSION     DAZAOD010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.192"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1004
                     /locus_tag="ACHDPO_002897"
     CDS             <1..1004
                     /locus_tag="ACHDPO_002897"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HFN3370447.1"
                     /translation="KGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFYMQ
                     QELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNVMG
                     TQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIFSC
                     VRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSKFG
                     ETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEIER
                     SYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVTW"
     gene            1016..2020
                     /gene="neuB"
                     /locus_tag="ACHDPO_002898"
     CDS             1016..2020
                     /gene="neuB"
                     /locus_tag="ACHDPO_002898"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HFN3370448.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
BASE COUNT          783 a          271 c          404 g          637 t
ORIGIN      
        1 ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt gaaattgttc
       61 gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt gaagaaaaac
      121 aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta attggtgata
      181 tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt tttcatgctg
      241 ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta aaaacaaatg
      301 tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa cattttgtag
      361 gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca aagttattga
      421 gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca atattttctt
      481 gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt tttagtaaac
      541 aaataaaaaa caataaagat attactttga cagatgttga tatgacacga tttatgatgt
      601 caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa tttggagaaa
      661 catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca ttaataaaaa
      721 tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta ggtatcaggc
      781 caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc tcatatgaaa
      841 atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg tacaaagatt
      901 atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg agtggacagg
      961 aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt ttatgatgaa
     1021 atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc tagatttagc
     1081 tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat ttcaaacatt
     1141 taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga aggataatct
     1201 taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc aatctgattt
     1261 tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta ctccttttga
     1321 tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa ttggctcagg
     1381 agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc cagttttatt
     1441 atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt tcatagatag
     1501 tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag atattaattt
     1561 attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact ccgatcattc
     1621 attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa ttgagaaaca
     1681 ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag atcctcagga
     1741 atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg atggtgttaa
     1801 gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc tagtggtcac
     1861 tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa aacgtcctgg
     1921 aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta aaagaccaat
     1981 aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact tatagtaagt
     2041 ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact acaag
//
LOCUS       DAZAOD010000188         2046 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000188 DAZAOD010000000
VERSION     DAZAOD010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2046
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.193"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..426)
                     /locus_tag="ACHDPO_002899"
     CDS             complement(<1..426)
                     /locus_tag="ACHDPO_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFN3370449.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
     gene            complement(535..1566)
                     /locus_tag="ACHDPO_002900"
     CDS             complement(535..1566)
                     /locus_tag="ACHDPO_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFN3370450.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          630 a          331 c          354 g          731 t
ORIGIN      
        1 aggaatctgt tttgattttg ttccatttga aatttctctc actcgctttt ttgtctcatc
       61 atcaaataaa atgaaagggt cttctaaacg atcgataaat acttccattg ttgttgttgg
      121 tagatgataa gaagtcatga caggcactgc accaaggtaa gacacagaaa cagctagaag
      181 gtatgtgtca aaagcggaac tcttataaat aataactttg tctccggatt tcactccaag
      241 atgagccaat tgataagccc gtttcaacac actttcgcag cattttttgt aagttgtttc
      301 aagtcctaat tctgggaaag ctgaaagtgg ctcatcaaag ataatcgggg tctcggaaaa
      361 gttagctgca gcttcttgaa aattcgtaaa taagttcaaa ggggaatacg ttatggtctc
      421 catcattcac actccattat cttttgttaa gtaatataca aattcaagat aatcgtaaca
      481 taatccttta tataataaca tagtttattg tgaaaaaaag atcatacatt tgttttatat
      541 ggaagaaacc cgaacgaatg ccgctaattc gtgataagaa aaatcaacca tcttttccca
      601 gatatcttga aaagaatggg atgagaggta tcgattacca cataaataat ttaccgcgtc
      661 agcatcatct aaatatagtt ctgcataata acgatatgtt tttctgcata gttctggcga
      721 tacgttttta tatactgtaa ttttgctcaa aatttggcga atagtccgag gagaaatttg
      781 ctgatcatgt gaggaacgaa aaacaaaaga attttcgtcc gtattttgtg ctgttaactt
      841 aaaatagttc tccagaaatg gcatcgcttc ttttggtatt ggtactttat tcagtctgtt
      901 ttcttttcta ttcagattaa gaatctgctt ggtcaaagat acatctttac gtttaagttc
      961 tactacttca tggatcttta atccgcaata cagaagaatg gcagtaattg caaggttcct
     1021 cggtctattc ttttcttcaa agctagcttc tctgcttgtt tgaaagcctt caatcgggat
     1081 aaacaaatgc tcaaaatctt tgaaaagttc tgcatcgata tatcgcggag ctgctttggt
     1141 tgtttccggt aaacttgtac ccaaaagaga aatctcttct tcaatcagtc ctttttgata
     1201 caaaaatcgt aaaaaatgat ttaatgaata ttgcttcctt gaaatcccgt aatagctatt
     1261 ttcaaacaat tgctccgttt cttggttcgc tgtagtttgg aacgaacgag tatgtcgata
     1321 gattttagct aagaaattct gataatcttg tttttctaaa tggataatca gctgatcatc
     1381 cacttcttca gaaaatactt ttctcaaata atcagtaaac agatgaaaat cttttgcgta
     1441 ttcatagcga ctgcctaatg aaagggaaga acgattttct tctaaaaact gttgaaagac
     1501 ggaagggagc aagtgtgtac gttgctttaa cttttcttgc agttgttttc tagttttgct
     1561 gtccattaca aattccctcc aatagtgttc attttctata ttttaccgca tttcatcaaa
     1621 tgaagataga cagtttgtct tgatcttagg aagcaaattt ttaactaagt actagctaaa
     1681 agatatgaag taagaagata catttttagt tattttatta gtgcagtcat tcttttgatc
     1741 ttttaattga tttatcctct ttttagctat gtggttactt catgagcaat gaaatggatt
     1801 tggttcgttc taatggcagg aggctctttc ttttatttcc gaaaaattag aaaacatttt
     1861 ttcagaatcg attggctctc catttattca ataatggttt gtctaacgat attgttggga
     1921 taattcttaa agaagtatta gaaatagttg gtacttcatt actttacatg aagatttatt
     1981 ctatggtagg agcaattata ttgagaatta atcctttttt atataagttg tttgcttatt
     2041 gatgga
//
LOCUS       DAZAOD010000189         2043 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000189 DAZAOD010000000
VERSION     DAZAOD010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.194"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            656..988
                     /gene="traE"
                     /locus_tag="ACHDPO_002901"
     CDS             656..988
                     /gene="traE"
                     /locus_tag="ACHDPO_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFN3370451.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1607..1948
                     /locus_tag="ACHDPO_002902"
     CDS             1607..1948
                     /locus_tag="ACHDPO_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFN3370452.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          713 a          271 c          430 g          629 t
ORIGIN      
        1 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
       61 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
      121 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
      181 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
      241 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
      301 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
      361 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
      421 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
      481 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
      541 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
      601 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
      661 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
      721 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
      781 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
      841 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
      901 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
      961 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     1021 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     1081 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     1141 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     1201 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     1261 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     1321 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     1381 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     1441 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     1501 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattga
     1561 tataaaacat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     1621 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     1681 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     1741 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     1801 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     1861 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     1921 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     1981 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     2041 ttt
//
LOCUS       DAZAOD010000190         1985 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000190 DAZAOD010000000
VERSION     DAZAOD010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.195"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..638
                     /locus_tag="ACHDPO_002903"
     CDS             <1..638
                     /locus_tag="ACHDPO_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFN3370453.1"
                     /translation="PYIIIGAGGHAKVIIETLRLENKLIYGFFDDKQNKMQDLKYLGK
                     INELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIAVHPSAIVAKEISIG
                     YGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPGVCLAGGVHVGVGTQ
                     IGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKKEGINFEF"
     gene            589..1770
                     /locus_tag="ACHDPO_002904"
     CDS             589..1770
                     /locus_tag="ACHDPO_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFN3370454.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            1783..>1985
                     /locus_tag="ACHDPO_002905"
     CDS             1783..>1985
                     /locus_tag="ACHDPO_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFN3370455.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFV"
BASE COUNT          706 a          259 c          415 g          605 t
ORIGIN      
        1 atccatacat tattattggg gctggcggac acgcaaaagt cattattgaa accttaagat
       61 tagaaaataa gttaatatat ggattttttg atgataagca aaataaaatg caagatctga
      121 aatatcttgg gaaaataaac gaattgaata gctgggcgga tagcaaaaaa aaaatctata
      181 aatttattgt agctattggt gactgtgtag taagaaaaaa gattataaaa aaattgaata
      241 tgccaagtga gcaatatgga atagctgttc atccaagtgc tatagtggca aaagaaattt
      301 caattggtta tggaactgtt atttttgcga atgctgtaat taacccagat gctgtaattg
      361 gagagcatgc tataataaac acaggtagca ttgttgagca tgattgtaga attaataact
      421 atgttcattt atctccaggt gtatgcttag cgggtggagt acatgtaggt gtaggaactc
      481 aaataggaat tggttctcaa tgtatccaga tgaagaaaat tggatcttgg tgtatgatag
      541 gcgcagggag cactattgtt aaggatattc cctcacattc cttagcttat ggcaatccag
      601 ctaaaattaa gaaagaagga attaattttg aattctagaa ttttattatc aagtcctcat
      661 atgggaggaa cagaagaaaa atatgttgct aaggctttta aagataattg gatagcgcca
      721 ttaggtgaaa atgtggataa atttgaagaa agtattacaa aatatactgg ttctaagggc
      781 ggagcttctg cgttaagttc aggtacagct gccatacatc ttgccttaag actgcttaat
      841 gttggaaaaa acgatattgt ctttgctcct tcatttactt ttatagctac agtaaatcct
      901 attttatatc aaggggctgt accagtgttc attgactcag aacctaatac atggaatatg
      961 agccctgttg cactagagag cgcattagaa gaagctgaaa gaaacaacca attacctaag
     1021 gcaatcatcg tagtgaattt atatggtcaa atggctgatt atgaacgaat tttagctatt
     1081 gcaaaccaat ttaatgttcc agtgatagaa gatgcagcgg aatcgttagg ttctacttat
     1141 aagggaattt cgtcaggctt atttgggaca attgggatct attcatttaa cggtaataag
     1201 atcatcacaa cctcaggtgg aggagctcta gtgtctagtg ataaaaaata tgttgagcat
     1261 tcaagatttt tagcaacaca agcaagagat caagcaccgt attatcaaca tagcgaaata
     1321 ggttataatt accgtctaag caatatttct gccggtatcg gacgtggaca aatggaagta
     1381 ttgaatgata gagtagctaa acgaagagaa attttcaatc gatataagga agctttttct
     1441 ggaattgata gaattgaaat gatgccagaa gtggatggca tggtgccaaa tcgttggttg
     1501 tctactttaa cgatcaatga ttataattct attgatcaag tagttaacgt aataaataaa
     1561 ctaaatgaaa aaaacattga aacaagagct ttgtggaaac cactacattt gcaaccagta
     1621 tttcaagggg taaaaatgta ttaccatgat aataatctta gtgtgtcaga aaagttattt
     1681 aatagcggct tatgcttacc ttctggaagt aatatgacag atagtgaaca agaatttgtt
     1741 attgatgagt ttaaaaaaat attcaagtag gtgtgatatt ttatgaacat aggaattatt
     1801 ggtttaggtt ccatggggaa aagaagactt agactcattc aagaacactt taatgatatt
     1861 ttactatgtg gtgttgatac taatgaggcg agacgaaagg aagttgaaaa ggaatttgga
     1921 ataccaactt ataatagtct aacagaggca aaaaatttgt ttgaaataaa ttcagttttt
     1981 gtttg
//
LOCUS       DAZAOD010000191         1984 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000191 DAZAOD010000000
VERSION     DAZAOD010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.196"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..150
                     /locus_tag="ACHDPO_002906"
     CDS             <1..150
                     /locus_tag="ACHDPO_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFN3370456.1"
                     /translation="YRKLDGNLEHQDQVTLFLDFPFLYPGKNEIKWTKNIHSFEIMPR
                     WWRKV"
     gene            147..>1984
                     /locus_tag="ACHDPO_002907"
     CDS             147..>1984
                     /locus_tag="ACHDPO_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFN3370457.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT          739 a          243 c          393 g          609 t
ORIGIN      
        1 tatcgaaaat tagatggtaa tttagaacat caggatcagg tcaccttatt tttagatttt
       61 ccatttttat atcctggaaa aaatgaaatt aaatggacga aaaatattca ttcatttgaa
      121 ataatgccta ggtggtggag aaaagtatga aaccaagaat atatagtcct actgaaacag
      181 atttctcaac gaatggctta ggaattttaa aggattgtac aagatgtgaa atatatgaag
      241 tagctaatgg aaaatatgaa ttagagttgg attatccttt aggaactaga tttgatgaat
      301 attttgaaaa tgactatcaa ataaaagcaa agccaaacga tcaagaagag tatcatatct
      361 tttttattga tgataaagat atagatactt ttttaaatac agtaactatt tatgctcaga
      421 gtcgtacaaa tcgacttgga agacgggtag tcactcttgt ggaagtggac tctaaaactg
      481 gtcaagaagc gatatcaatt attgaaacta aaatggataa aaaatctgac atacgacttt
      541 attctgatat tacggctgtt tctagcacaa tctttgaagc gagaaatgtt ttaaattgta
      601 ttgctggtga acaaggatca ttgcttcaat attggggcgg agaaattaaa cgtgaaccat
      661 ttaagctttc tttgttaaag cgaagaggtc gcaataatgt tggaacgatt cggtatggaa
      721 aagatatgtc tggtttgaag gtcaaattag attggacagg tataaaaaca agaattattc
      781 catatgctga tcctcaaagt gaagtaggta cgactaatcg aatttatggt tcgccagtag
      841 atagtgccta tattaataac tatcctgatg tctatacaga acatgttcag tttacagaag
      901 aacaaggagt aaaagacatt aagagcttaa ataaaatagc taaaaattac tttaaaacga
      961 tcaatcctgg ctgtgataag cctaaagttt ctattacggt tgaatttgat aagttgactg
     1021 atagtgaaga agcgaaagaa tttgcgaaga ttagaaatta tggtctgttt gatacattta
     1081 aaatatatca taaaaaatat aatatttatc ttgaatcaaa ggttagtgga ctacaatacg
     1141 attctttatc tgaaaaaact ttgaaattag aagcaggaga cattcaagtt gctttttatc
     1201 agcaacaagc tgtaactatt caggataaat taaaagatta tgcaacgaat aattatatga
     1261 gtgattttaa tgattatgtt tcttcaatga ttacaggtca aggcagtgca ggaggatatg
     1321 tagttttatg gccaaaagaa aaaccttcca acatctttat tatggataat ccagatttag
     1381 aaaaggcaag agaagtacta agaatgaata aaaatgggat tgctttttct aagaaaggat
     1441 ggcgggggcc ttttaattca gcttggacat tagatagtat atttaatgcc aattttatac
     1501 aaactggatt aatcaaagca gatatctttc aaaattcttt taacaagact ggagatgtat
     1561 tgaaattagt taatggacta ctccaaattt ggaacaacaa aaagaaaata atggagttaa
     1621 ctaaaaaagg aatggaattt tggaattcta agggttcaat tggaacgatt ggaacaactg
     1681 attctgttgg taatcctttt cctggggctt ctactccaac ccctattgaa gataattctt
     1741 tagttattcg tacaaatgga gacggcaaat atattttgat ttctcctaaa gtaggaaaag
     1801 gattagtttt attaggaaat ggtaaagcaa tttattttgg agacttagat gtacaaggaa
     1861 aacttacagt taaaggaaaa gaaataattc ctggacaagg tggtggtcca tcgggaggtg
     1921 gagaatctac tggtgggtat cctagtgaat taaaaacaga tgcagaaaag agagcttgga
     1981 gaat
//
LOCUS       DAZAOD010000192         1969 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000192 DAZAOD010000000
VERSION     DAZAOD010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.197"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            270..836
                     /gene="amaP"
                     /locus_tag="ACHDPO_002908"
     CDS             270..836
                     /gene="amaP"
                     /locus_tag="ACHDPO_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFN3370458.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            849..1037
                     /locus_tag="ACHDPO_002909"
     CDS             849..1037
                     /locus_tag="ACHDPO_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFN3370459.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1050..1607
                     /locus_tag="ACHDPO_002910"
     CDS             1050..1607
                     /locus_tag="ACHDPO_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFN3370460.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1639..1881
                     /locus_tag="ACHDPO_002911"
     CDS             1639..1881
                     /locus_tag="ACHDPO_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFN3370461.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          717 a          305 c          404 g          543 t
ORIGIN      
        1 aaatagaatc ttgtaataat aactgagcat aatctttgca atttttaatc ttgaataata
       61 tcctttaagt atagccagca atcaaaagta aatagagaat aagtaagcaa ttgttatttc
      121 agtatcagac tggcaataaa acgccgttat gatccagcaa tgtttggtag cgctttattt
      181 actgatgcta tgctaactgt tcgctatcta tactgtgatt gtcggtagag ttatttacag
      241 ggtaaaaata agtttatagg aggtggaaaa tgaataaggg gttaaaaata atcggtgtta
      301 tcatgagttt actgctactt tcagtatttc tagcgattgc gttgatcaat gcgccgtata
      361 ttatgcctga acaattggaa cgatttcgct tctttacttt aacgaattac tacatgcaac
      421 aatatatttt ctgggcagct gtagtatttg ccgttcttgc tattatcatc ttgctagtcg
      481 ttcttttcta tccaaagtca agaggaactt tcgttatgaa acgggaagat ggcaaactaa
      541 caatcgacaa aaaagcgatc gaagggttgg tacgttccca tttacacgaa gaagagttca
      601 ttcattcacc taaagtacgg atacgttcaa cgaaaaatcg aatccatatc catgtcaacg
      661 gagacttgaa acgaacttct tcattagtag ggaaaacagg tgtattgatg caagatatcg
      721 aagaagaagt aactaaagta ctcggaacaa aagaaacggt caaagtggca gtcacataca
      781 gcggttatga agaacaagaa gatacaagag actacaagca ctctcgagtg gaataggagg
      841 gccaaataat gaaagaacta ttttcagcat acaagctccc tattatcttt gggggtcttg
      901 gactactgct agctgtttta tggttaacga ttggattttt caagacattg ttgatcataa
      961 tcatgacagc aattggcgca ggaatcggtt tttatttgaa acagtcagga atagttgatc
     1021 aattttttaa atcataggag gaaacaaaga tggaaaacaa aaacatgaat acaacaaatg
     1081 gatcagtttt ggcaaatgaa aaaggagaaa accgcatgat gaatggtgaa ttgacttatg
     1141 aagacaaagt catccaaaaa atcatcggtt atgcattgaa agatgtagat ggtctattga
     1201 cattagatgg cggatttttc tcaaatatgg ctgaaaaatt agtcaacaca gataacgtaa
     1261 cagcaggtat caatacagaa gtaggtaaga aacaagtagc tgtggatcta gatgtgatcg
     1321 tagaatacgg taaagacatc gaagatattt acaaccaaat caaagaattg atcagtactg
     1381 aagtaaacaa tatgacacat ttagatgtta tcgaagtgaa tgtgaatgtt gcagacatca
     1441 aaacacaaga agaataccaa aaagatcaag aaacagtaca agacaaagta acagaagcag
     1501 caaaatccac aggacaattt gcttcacgcc aaacagataa agcaaaatct gctgtaggca
     1561 aaggtgcaca aaaagtcaaa gaaaataacg aaccacgtgt acaataagaa gtaagaagtc
     1621 agttaggagg aatttaaaat gggatttatt tgggcattaa tcgtcggcgg tatcattgga
     1681 gcaattgcag gagcaatcac gaataaagga tcatcaatgg ggatcatcgc aaacatcatt
     1741 gctggtttag taggttcagc aattggacaa gctttactag gaacttgggg accaacaatt
     1801 gcaggaatgg ctatcattcc atcattgatc ggtgcaatca ttttagtatt agtcgtttca
     1861 ttctttgcac gtaaattata agcaaattga agaaaaactt atgttgaaat gaagaacaaa
     1921 tttgagaacc gtagcgacac tcgctgcggt tcttttttat atattttat
//
LOCUS       DAZAOD010000193         1880 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000193 DAZAOD010000000
VERSION     DAZAOD010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1880
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.198"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            89..841
                     /locus_tag="ACHDPO_002912"
     CDS             89..841
                     /locus_tag="ACHDPO_002912"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFN3370462.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            846..1793
                     /locus_tag="ACHDPO_002913"
     CDS             846..1793
                     /locus_tag="ACHDPO_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFN3370463.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          651 a          258 c          374 g          597 t
ORIGIN      
        1 tttctttgaa aacgtagtaa caggcaaaga aaactggaat gatttatatc atgcaaacga
       61 agtattgaaa atagctgagg agaaataaat ggaaatttta tttactattt gtggtagagc
      121 tgggtctaag gggtttaaaa ataaaaattt gaaatatttg gcaggaaagc ccctagtcca
      181 tttcgcttta gcaatgatag atatctatca acaaaaacat cctgaacata attgcacgac
      241 ttgtttgaat acggacagta atgagttagt agaattgacg actaagttaa atccgtctgt
      301 gaaaattgta gaacgtaaac ctgaattagc tacagatact gtagggaaaa ttgaagtgat
      361 acgtgattca ttcttacaac tagaaagaga agataatata tttgatttaa ttatagattt
      421 agatttgact tcacctttac gtgaagtttc taatcttgaa gaattaatag atgaacatct
      481 aaaaaattta gataaagacg tctacttttc agttgtttct gcaagacgta atccctattt
      541 taatatggta aaaagaattg aaaatgaagt tactatagtt aataaatcaa gatacacatc
      601 taggcaacag acacctgaag tttttgaaat gaatgcctca atgtattctt ttaaacctga
      661 atttctaaaa aaaagtaatt atatttttga tgggcaatgt gggataataa aaatgagaga
      721 ttatctaatt ttagatattg atagtgaaga agattttaaa tggttagaat ttttgtttcc
      781 taaattttta gaagattctt cggagcttca agatatctat aattatttat atcggaggta
      841 aaaggatgag ctgttatctt atcaccggtg gggctggctt cattggttct accttagcca
      901 atcatttagg agaagaacat gtggtaatcg tcgtcgatga cttatcaatg ggaaaagtag
      961 aaaatcttga tatgacgaaa aatatcactt ttattgaggg agatgtcgct gagaaatcct
     1021 tgatggaaga gatcatgaaa gctaataaat ttgattatat ctttcattta gcagcagttg
     1081 ctagtgtggc agattcagtt gcccgaccag tagaaacaca tcgtgtgaat tttgaaagtg
     1141 tattaatgat tttagaattg atccgcaagt atcaacctga tttaaaacgg atcgtgttta
     1201 gttcttcagc ggctgtttat ggggatgaac cgactttacc aaaaaaagaa gagtccgtga
     1261 ttcgcccatt gacgccttat gcggttgata aattcgctgc agaacaatat gtgctagatt
     1321 attgtcattt atatgatgta cccggtagcg cagttcgttt tttcaatgtc tatggtccaa
     1381 atcaaaatcc gaattctcca tacagtggtg tgatttctat tctcgtagat cgctataaga
     1441 aacaaatcgt aggagaagca acttcattta cattatttgg tgatggaagc cagtctagag
     1501 actttgttta tatagatgat gtaatccaag cattactttt agttgcgaat gaggaagctg
     1561 cactggggaa acaattcaat gttggaacgg gtaaagcaac cacacttttg gaattgattc
     1621 atgcaatcaa tgaaattctc ggtgtagaat tgacacttga atacaaagaa gagcgttcgg
     1681 gtgatatcca tgactctcta gcagatatta ctaagatcca gtcaattggc tatcaaccga
     1741 aatatggtat tttaagtgga atgactaatt atttgaaaac tgaaatcaat taaaacatac
     1801 taagataaga ttagagggta aattcaggct ctttgtcaat aaggactgat gagttttgta
     1861 aaatcaaatc tgggatagaa
//
LOCUS       DAZAOD010000194         1859 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000194 DAZAOD010000000
VERSION     DAZAOD010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.200"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            416..1804
                     /gene="ltrA"
                     /locus_tag="ACHDPO_002914"
     CDS             416..1804
                     /gene="ltrA"
                     /locus_tag="ACHDPO_002914"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFN3370464.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT          654 a          343 c          444 g          418 t
ORIGIN      
        1 aacttggtgg tgaaagtcca ctacaggctt ggcagtagga actgttagcg aaagacaagg
       61 cggcaatcgt gaggttgtgg ctgaaggaag tcggacgcaa actcctgaac tgacgaacag
      121 aaactagata caaggctgaa ttaggtcgga taagtcttca tcacaagaca aagtccaata
      181 ctgcccgaaa cctatacagt aaatctagca gttacatggg aggaaagttt tcactcttac
      241 cgggggagat ctcatgaggg tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc
      301 atggcgacat gatggtgaat catgagaagt cagccgaggt catagtagta acgacactga
      361 ccgttacgaa ggactgaaca ataagaatct tgaataattt aggaggtgtg agaagatgcg
      421 acgaccgcag aaaacaagaa aacttggcta tcatcaaaga gctagtgtgg aacacgaagg
      481 gtatgatgaa gtgcgcagca cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa
      541 tctgtttggg agaattctag atcggaataa tctcaatcaa gcgtatcttc aagtagtcag
      601 aaataaaggg gcggctggtg cagatgggat gaccgtcgat caactgcttc cttacttgaa
      661 agagcaccgc gaggaattac tatccaattt acgccaaggg aactataaac ctcagcctgt
      721 tttgcgagta gaaataccga aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt
      781 tattgatcgt atgcttcaac aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga
      841 attctcagat aatagttatg ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa
      901 agcaaaatct tattatgaac aaggttaccg atatgtggtg gacattgata tgaaagccta
      961 ctttgacacc gtaaatcacg ataagctgat gtatttcatt gagcggaaag taaaggacaa
     1021 acaagtccta aaactgatcc gtcaatactt aatgagtggt gtaatggaaa atggactcat
     1081 cacaacaact gaagaaggaa cgccccaagg aggcaatctc tctcccctgt taagtaacat
     1141 ctacctgaac gaatttgatc aagtgctaga aaatctagga cataaatttg ttcgatacgc
     1201 cgatgactgc aatatctatg ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc
     1261 cattcaattt ctcgaagaac aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg
     1321 aagtccattg aaacgaaagt ttcttggatt ctgcattctg ccaacaaaga aaggtattaa
     1381 aattcgccct cacgcaaaag caaaacagcg tgtgaaaagc aagctcaaac aactcactaa
     1441 aagaaaccgt ggaagaagta tccaacttat tttaaaagaa atcaagcaac taatgactgg
     1501 ttggatcaac tactatggaa ttggtgagat gaaagaattc atgagggagt taaacggttg
     1561 gttgaagcga agaatcagac aatatatttg gaaacaatgg aagaatccaa gaaccaaaag
     1621 aaaaaatctg attcgtttag ggatcgataa agcgaaagcg tatgaatggt caaatacaag
     1681 aaaaggtatt tggtcagtct ccaaaagtca tattcttcat cgatcattaa cagacaaaga
     1741 actggcccgc caaggatatg aggacatctc cttgaagtac cagttcgtac actcaactta
     1801 ttgaaccgcc gtatacgggt ccgtacgtac ggtggtgtga gaggggcgga aggtcagtt
//
LOCUS       DAZAOD010000195         1852 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000195 DAZAOD010000000
VERSION     DAZAOD010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.201"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1586
                     /locus_tag="ACHDPO_002915"
     CDS             <1..1586
                     /locus_tag="ACHDPO_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFN3370465.1"
                     /translation="TLPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVP
                     VEVTDNRSDADKYEPTVEGEKVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTN
                     TPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNV
                     TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNA
                     DKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTY
                     PDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYT
                     WKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTG
                     KTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNV
                     VVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGL
                     ILLGTLGLLGYKNRKKENE"
     gene            1720..>1852
                     /locus_tag="ACHDPO_002916"
     CDS             1720..>1852
                     /locus_tag="ACHDPO_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFN3370466.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     "
BASE COUNT          727 a          286 c          402 g          437 t
ORIGIN      
        1 caacattacc agaaggaaca acagtaacag atgtcactcc tggtggtacg attgatacca
       61 acacaccagg taattacgaa ggggttatcg aagtaacgta tccagatggt acgaaagata
      121 cagtgaaagt tccagtagaa gtgacagaca atcgttccga tgccgataaa tatgaaccaa
      181 cagtagaagg cgaaaaagta gaagttgggg gcacagtaga tctaacagat aatgttacta
      241 acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc ggtacaattg
      301 ataccaacac accaggtaat tacgaaggtg tcattgaagt aacgtatcca gacggtacga
      361 aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctgacgcc gataaatatg
      421 aaccaacagt agaaggcgaa aaagtagaaa ttggaggcac agtagattta acagataatg
      481 ttactaactt gccagcgtta ccagaaggaa caacagtaac agatgttact cccggcggta
      541 caattgatac caacacacca ggcaattatg aaggtgtcat tgaagtaacg tatccagacg
      601 gtacgaaaga tacggtgaaa gttccagtag aagtgacaga caatcgttct aatgcagata
      661 aatacaatcc tgaaggacaa aaagtgacta cagacttaaa taaagagcca gatgcatctg
      721 agggaattaa gaacaaagaa gatttaccaa aaggaactac ttatgcttgg aaagagaaag
      781 tagatgttag cacagctgga aataaaaaag gtactattgt agtgacatat ccagatggat
      841 catctgatga agttgaagta gacgttacag tgacagatac tcgttccgat gcagataaat
      901 ataatcctga aggacaaaaa gtgactacag acttaaataa agagccagat gcatctgagg
      961 gaattaagaa caaagaagat ctaccaaaag gaactactta tacttggaaa gaaaaagtag
     1021 atgttagtac agctggaaac aaaaaaggta ctgtagtagt aacatatcca gatggatcta
     1081 aagaagaagt agaagttact atttctgtag tagataaaaa agcaccgaat aaacctcaag
     1141 ttgatcctat tacagagggt gaccaaattg ttactggtaa aactgaacca aatgcagagg
     1201 tgacagttac attaccagac ggaagtcaac accatgggac agctgataaa aatggtaatt
     1261 ttacagttaa agttcctaaa ttagaggcag ggacaaaagt gatagtaact gcaactgatg
     1321 aatctggtaa tactagtgaa cctactaatg tagttgtttc ttccaacaaa aaagacagtg
     1381 gaaaaaacgg tagtaaaggt agtaagactg acaatcaagg tagcaacagc aatcaagaca
     1441 aaaatagagg caaaagccag tcctcaaaag tttttcctaa gacgggagag agtgacagta
     1501 atatctttac tattagcggt ggtttaatac tgttaggaac gttaggatta ttagggtata
     1561 aaaatcgaaa aaaagagaat gaatagaaaa tcaatttctt aagtcttctc tgagaagagg
     1621 aagaatcttt ttcttcctct ttttgctttt ttatgatggg aaataagtgt tagttaaaga
     1681 tgaatatact ttttatagaa aggaaaagaa tgtaattaag tggaaaaaat agtaattatt
     1741 ggttcaaacc attcagggct agccgcagct cgatttctaa acttaagcga ttcaaattat
     1801 gaagttattc taatcgataa aaaatcagaa attagttact tggaatgtgg ga
//
LOCUS       DAZAOD010000196         1837 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000196 DAZAOD010000000
VERSION     DAZAOD010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.202"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..408)
                     /locus_tag="ACHDPO_002917"
     CDS             complement(<1..408)
                     /locus_tag="ACHDPO_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3370467.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILD"
     gene            complement(419..1087)
                     /locus_tag="ACHDPO_002918"
     CDS             complement(419..1087)
                     /locus_tag="ACHDPO_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFN3370468.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(1217..1801)
                     /locus_tag="ACHDPO_002919"
     CDS             complement(1217..1801)
                     /locus_tag="ACHDPO_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFN3370469.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
BASE COUNT          649 a          308 c          245 g          635 t
ORIGIN      
        1 atctaatata tttgaaagat ctaataattc agctaattca ttgattcttt tatccatatg
       61 ctcttttgta aatccaaagt tttccatcga aaatactaac tcactcgttg tatttgttgt
      121 aaagaattgt cctctaggat cttgacttac gtagccaata ttttttgata tactttcttg
      181 tgttaaggat tgtagcgagt tattttcaaa taaaatttcc ccaaccaatt ttccgtcata
      241 aagtcttgga ataagtccat tcattaactt taatagtgtg gatttcccac tcccagaaga
      301 accagtaatc aatgtaagac tgcctttttt tattgaaaaa ttaaggtcaa caagcgcttg
      361 ttccttaaca tccttatatg aaaaagaaac attgttaaat tcaaacaatt ctttcacctc
      421 aaatcaaaat acttaagaaa aaaatagtaa cggaaaacag gatgatatag tctaataagc
      481 tcatgtttgt tttatagtaa gaacttcttt tcacaggaga ttctatcccc tttgttattg
      541 cattagcggt catttcttca gcaatcatag ttgcacgtat aagaacggga actaacagaa
      601 attccaaata ttgcagaggc tgaaaaaaag acaagcgaat gtttctcatt tttaaagatt
      661 ctttaatcat tcttatttca gaacgataag tcggaaagaa tctgatcact actgtaatac
      721 ttaacattat ttttttcggt aaatgtattt tttctaaaga ggataataat tcattgctag
      781 tatagacact aaccaacaac catgagatca ttacgaccgg caacattcga aatacaatat
      841 ataaggatgt cgcaaaaaat atagtaaaaa actctatctt gatagcatca ataattttca
      901 ttactaaaaa cagaactgaa taaatcaaga tgaaataaat acatgtcttt attttacgaa
      961 acatcaatac taaaactgta gcaataatga aacaccccac ttgaaatata tttccctttc
     1021 ctaaaaaaat aatgaccgga aaaaaaatat ttaaagtaat caaggttaac ggattgattt
     1081 ttgacactct ttcacctcca aaaaataaga tcgcactgtt atcttaagct gataaaaatg
     1141 caccgttatt cagataacag tgcgatctta tcaaaaagca taactgagaa caattctcaa
     1201 tgcaagcttt ttttaattaa ctcagtaatt caatccaccc aggaacagaa aattgataca
     1261 atcttctggt taatagcata gtcttttctt ttgaatagct atgcttcaat atatcataga
     1321 atgtagcgta gaatgagtaa atgtagaagt ggatttcttc ttcattaaag actaaatttt
     1381 gattgatcat tccgatagtc tttaacttat ctagacaaca gactgtcttt ttcgtcacaa
     1441 atgatgtaat tttttcaaca atatcttgat atttggttcc agctgattgg aataaaatca
     1501 aatcgaatat acgtttattc tcaaaaatat aattaataaa tggatctaat tcattgaagt
     1561 tctctctcca acttttctct atatctatat tttctaagtt taagaggtat ttggtaaact
     1621 cttcattata catattaata agcgcattaa tatgcggctg aataatttct tcaaataacg
     1681 cttccttaga agtaaaatgt ttataaaaag cacccgtagt tacgcctgcg gtcaggcaca
     1741 gttgccttat cttagtttgc tgaaatcctt ctttttcaaa atggcttagt ccactttcta
     1801 ttaacttttg gtgagttata atataatctc tggtttc
//
LOCUS       DAZAOD010000197         1781 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000197 DAZAOD010000000
VERSION     DAZAOD010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.204"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..242)
                     /locus_tag="ACHDPO_002920"
     CDS             complement(<1..242)
                     /locus_tag="ACHDPO_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HFN3370470.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDL"
     gene            complement(420..740)
                     /locus_tag="ACHDPO_002921"
                     /pseudo
     CDS             complement(420..740)
                     /locus_tag="ACHDPO_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(856..1377)
                     /locus_tag="ACHDPO_002922"
     CDS             complement(856..1377)
                     /locus_tag="ACHDPO_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370471.1"
                     /translation="MDKPFLDSVREYLSNPKSTLFPHEDYKIIMNYYLPIGAPQNSKI
                     KIPNDIVNDGDTHNVIKGFLPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGL
                     DLKNLLCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLM
                     ELKKYSNTQTKFS"
BASE COUNT          550 a          326 c          249 g          656 t
ORIGIN      
        1 atcagatctt cttttgattc ttcatctgaa agtaattcac gatacaacat cgtttgtttg
       61 cttactgtgt catattcctc taaggattca tctgctaaaa gaaccacttg ttccaacaaa
      121 cggtcggata aatatttata gaaaatcagc cccaataaat aatttttata ttctgacgca
      181 tccattttac tacggagatt atctgccgca ctaaataact tctgatttaa ttctgcaccc
      241 aaaaagatac actcctatct cttatttaaa gttgctatat accctcttat tttagcatac
      301 tcagttttag aaaaagcaaa aaaataaaga aacttattct tgataacaag ctacgtgacg
      361 tatatcccta acacaaaaat agccatatcc tttggtttgg atacggctat ttgatattac
      421 tcattcaatt atcaaatcac agtaggtgtg aatctcatcg ggatcggcaa tatctacttc
      481 tgattaggat caaaggtgat tttctcaata aaggtgtgat acaaagcttt aacttgcttc
      541 ttctcactct ggataagaaa gcaatccaaa ctagtcaata tctgttggac atctttgact
      601 tgaatcggtt ccccttgttg ttgaaagatc cctaagattt cattctctcg aatttgtaac
      661 tgtcttcgtt tttcagtcaa ttcatttaaa cgatctttta acatcggaaa caattcggga
      721 ctatcttcca aagcagcttc ctgtttttgc tctaatagtt agattttgcg taccattttc
      781 ttcttttatt ttccttcgat tgctgatttt aatatagtct aaaggaaatt tatatttatt
      841 gtattcttta taacttcaag agaacttcgt ttgagtatta ctgtattttt ttaattccat
      901 aagaaaatta gttattacct gccacctaat cagcaaatct gaacctgagt caatataatt
      961 aatattattt tccatctcca acattgtaag tactgttggt gttaatatag ggactttgta
     1021 caattgtatt tttttgattt tatcatctgc acaaaggaga ttttttaaat ctaatccttc
     1081 ttttatttca aaagttgaat tttttaaatc tataagagta aaaccaattc cttcatactg
     1141 aatttctgaa aatcgaattt ttctcccagt tgatagatca aggggcagaa aaccttttat
     1201 tacattgtga gtgtcaccat catttacaat gtcattagga attttgattt tagaattctg
     1261 tggagcacct attggaagat aataattcat tataattttg tagtcttcat gaggaaataa
     1321 agtactttta ggattgctaa gatattctcg taccgaatct aagaatggct tatccattga
     1381 atcttcatcc ccatttaaac taaaaaacat tcctacaatt gcttttgcaa ctctaagtga
     1441 attcattttc tttattgaat gtgttaaatc agacttacca ttctttaaac ttgtattgtt
     1501 ataaaggaaa tttttattgt cttctgcaaa tctaatatat tcctcaacat actcactacc
     1561 aaaaaaacta ttacatttac tacataacgt attggaatgg caacagtttt tttgacaaat
     1621 tttataaggt gcagaacttc tttccgtatg ctattccgat tgtccttgac aatgagcctc
     1681 ctcggatgtg acgatcttcg gcaggagcta acagttaaag ttagactgcc tcgctagcgt
     1741 tagcacatcc gagctcatta tcaaggattc gctgcgccaa t
//
LOCUS       DAZAOD010000198         1765 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000198 DAZAOD010000000
VERSION     DAZAOD010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.205"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1604
                     /locus_tag="ACHDPO_002923"
     CDS             <1..1604
                     /locus_tag="ACHDPO_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HFN3370472.1"
                     /translation="ETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHK
                     MFRPDNAYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPI
                     REGRTMEDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYN
                     GDINNRLARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFS
                     RTNRTYPEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQA
                     YGKLKEVSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQ
                     IQLLEEQIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTY
                     AANSSDAREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQAS
                     DNLIHAFSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFK
                     YPQEMKRAWRKMLDDELIPLENELR"
BASE COUNT          640 a          283 c          357 g          485 t
ORIGIN      
        1 tagaaacata tgcagagtat tcaccggaac agatcaatcg tatgatcgat caaatggagt
       61 ctgtcaaaaa agaaagttat ttggacccta ctgtttttga agcagaggaa catatccaaa
      121 aagtcattca taaaatgttc cgtccagaca atgcctatac aaaatttgat tttcgaaatg
      181 gccgtccaac gaagtctgcg atcttaacca cgagttccat tgatatggcc aaaaagtatt
      241 atcgggccat caaagagatg acgaaagaat ctgattggtt aataaaagag tttcccaatc
      301 agcctatccg tgaaggacga acgatggagg atcctgattt cccacgaatc gctattacct
      361 attcattaga agaaaatagc cgagattcaa gtgcccaaca agaagaaatg caaaaaatta
      421 ttgaggaata taatcagtat tatgatactg cctggtcact agcagacatt gagcgttata
      481 acggagacat caataatcgt ttggcacgaa aaagagcgga attcaaacaa tttgggaaac
      541 aaatcgattt agtaatcgta gtggatcgtc tattgacagg ttttgacgcc cctacgattc
      601 aaaccctatt tgtggatcgt aatctagagt atgcaggatt gatccaagcc ttttcacgta
      661 cgaaccgtac gtatcctgaa aaaacaaaag gactaattgt tactttccga aagccagcga
      721 caatggagaa gaatgtcgag gatgcgacaa aactgtattc agaagctaaa gaagaatcgg
      781 gtttgattta tccaagttac caagaatcca aaaaaagatt caagcaagca tatggtaagt
      841 taaaagaggt ttcatccatg gaatccattg atgaacatac gccacttgaa atccgtatcg
      901 agtacgtcaa agcatttcaa gaattgaatc gtgcgtatga atcgttagtg acttatgatg
      961 attacaatga tgacatggtg caatcttcaa ctttgaacaa tcaaattcaa cttttggaag
     1021 aacaaattgg cgtgtacgag accgtgaagg gttcattgat ggaggaagaa ccagaaaaag
     1081 agggagaaga tttttcaacg atcgaatttt atagtgaaaa taccactaag ttgtatgata
     1141 ttgattctac ttatattgat caattactag gaacttatgc tgcgaatagt tcagatgcac
     1201 gagaagaaat tgaaaaagct ttggctaaat tgaataaaac agaaggagtc aaagaagttt
     1261 accgacaaat tttaaatgca tttgatgtgg ggactttaga tagtaatgaa gatatctttg
     1321 tcattaaacg tcgctatttt acacaagcaa gtgataattt gattcatgcc ttttccaatg
     1381 agtggtttgt ttctgagaaa gaattacatg cttctaatct gcaatatatg ccaggtgaag
     1441 atccaattcc taatatgaaa gcaattatca acagtaagga ttacgaagga tataaagcca
     1501 aacatccaga agcgaaacca tttaaatacc cacaagaaat gaagcgagca tggcgtaaaa
     1561 tgttagatga tgagttgatt ccacttgaaa atgaattgag gtaaacgaga agagttaaga
     1621 aaattgtacg attcaaagat agtagtaaag tggaagtgta gaaaataggg atagatgtct
     1681 ttttacttgt tcacatttta taacggagta tttaagaaag ctattgaata atgattcttc
     1741 catctttttc attcatttac cggtt
//
LOCUS       DAZAOD010000199         1711 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000199 DAZAOD010000000
VERSION     DAZAOD010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.206"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(310..1479)
                     /locus_tag="ACHDPO_002924"
     CDS             complement(310..1479)
                     /locus_tag="ACHDPO_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFN3370473.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          574 a          272 c          240 g          625 t
ORIGIN      
        1 caaaaaaatt aaccttactt atatgaagat tctaagctct tatttaaatt ttagacgggc
       61 agttatccgt agaagttctt agaatagcta atttacataa ttaaattata tgaaatttaa
      121 gtttgaacaa tatactaaga actcccctta ctataaagtg aaataaatta gcatatgaat
      181 aaccgtgcta ccaagctttt cattaataaa atatttttat taatatttta taactttacg
      241 caagatcata attttgtcgg gagcgtcaat aattttgtgt aaatggaaaa gcccattctg
      301 ttgatcaagt taaaacattg attctaatgt atcatgtatt tctttaaaac ctttatgaac
      361 tcggcataga aacttttgat tatagttgtt gaattgagat actagaaatc tctccagaga
      421 ttcttcatta ggaaattgct cttttctttt ggtatatttc tttaattgtt tgttaaaacc
      481 ttcaatcaaa ttagttgaat aaatagttct tctgattgac ggagggaaat tataaaaggt
      541 taatatagca ggattcatga gcaatttaac cactcgtgga tactgctttt tccatttatc
      601 tatcataaac cttatttgat tatttgcttc ttcttttgaa cttgcttgat aaactaattt
      661 gaaatcgcta cagatttctt gtcgatcact aacacgaacc ttatgagcga tatttctaga
      721 tatatggaca caacattgtt gaaattgagc atttggataa acactatgaa tactatcgtt
      781 aatgccactt aaaccatcag ttacgactaa taaaacctct tttaaaccac ggtcttttag
      841 gtcttgaaga atctctttcc aaacataagc agattcagtt ggagcaagac taaacccaag
      901 aacctctttg gttccatcta atcgaatgcc aattacaata taaactgctt cttttgaaac
      961 agtttgtctt tttaaaggaa tgtgagtagc atccataaaa atgacagagt atctggattc
     1021 taaggacctt tctttaaagg caataatatc ttcagaaact attttagtca tatttgaaat
     1081 ggtttgtggc gtatagtgat gcccgtacat tttttcaatc aattcagaga tttcagacat
     1141 agtaattcct ttttgaaata gctgaataat agtggtttct aaagagtcat tggttctttt
     1201 ataagcaggt aaagtttgtt gagaaaactt accatttcta tctctaggaa ttaccaaatt
     1261 taattctcca tactctgttc tgaatgaacg tgaataattc ccattacggg aattacctga
     1321 attgaaccca gcacgatcat atttttcata atcaagaaaa gctgttaatt cagcctgcaa
     1381 taatgaatta acagctaatt ctaaatgaca tcgaaataat tcatctaaat cacctttatt
     1441 gattagtgtt tccataattt ctgtagtaaa attgggcatg agaaagtcct cctataaaat
     1501 ttcggttgtg gtaactttaa ttttacagaa tggactttct ttttttctac cctaaatatc
     1561 tatttacaca aaatatttta cgctatcatt ttgtctgtgt agatatttcg ttatatcact
     1621 aaagataata agatttaatg acctcattaa tattgtttgc taggtccaaa ctcttattaa
     1681 actttctttg ctataaaacc caaacatagt a
//
LOCUS       DAZAOD010000200         1682 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000200 DAZAOD010000000
VERSION     DAZAOD010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.207"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            200..742
                     /locus_tag="ACHDPO_002925"
     CDS             200..742
                     /locus_tag="ACHDPO_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370474.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1347
                     /locus_tag="ACHDPO_002926"
     CDS             898..1347
                     /locus_tag="ACHDPO_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFN3370475.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMATIALDNEHPRI"
     gene            complement(1377..>1682)
                     /locus_tag="ACHDPO_002927"
     CDS             complement(1377..>1682)
                     /locus_tag="ACHDPO_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFN3370476.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          636 a          240 c          324 g          482 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgg aatggcaaca
     1261 ctttttttga caaaaattat aaggtgttgt gaatgctgcg gtgttatggc tacgattgcc
     1321 cttgacaatg agcatcctcg gatctgattt tctccggcag aagcacaatc attcaattac
     1381 gctgcctctc cagaggtatc agatccgcgc tcattatcaa ggattcgctt cgccaatctc
     1441 tgttgtcgaa tttggatcgg tgtttcatac gccaacgtgc catgtaagcg tagatagttc
     1501 caccaatgca cataatcaaa caattctaga cgtagctgtg ccagtgtctc aaattggtat
     1561 tgatgcacga attctacttt gacagattta taggttgatt ccacaacggc attatcatac
     1621 ggacaaccct tcctactcaa tgaacgagta attccaaaac cattcagaat ctcatgaatg
     1681 gt
//
LOCUS       DAZAOD010000201         1675 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000201 DAZAOD010000000
VERSION     DAZAOD010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.208"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(109..762)
                     /locus_tag="ACHDPO_002928"
     CDS             complement(109..762)
                     /locus_tag="ACHDPO_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFN3370477.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1050..>1675
                     /locus_tag="ACHDPO_002929"
     CDS             1050..>1675
                     /locus_tag="ACHDPO_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFN3370478.1"
                     /translation="MDNHTRKLLVLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPR"
BASE COUNT          541 a          303 c          232 g          599 t
ORIGIN      
        1 aatatgtttt aggaaagata aaaaaaatta atgaatgaac taatataatt attattccaa
       61 gaacagaaaa tatttgtatg aacatttttg gaaatatctt taattttttc attttctctc
      121 caatttatat cctacatttc ttatagtagt tatacagtct aattgtaatt tttttctaag
      181 ttcttttata tatacatcta ttactcgatc ataaggagtt tcttcgctat ctttccatac
      241 ataatcaata atttgcattc ttgttaacac ttgtccatta ttatccaata aacattttaa
      301 tacttctagt tcttttgcat ttacatctat ttcttcacca tttattttag ctgtatagct
      361 attaaaatta accgatagat ccttatattc aaacttctct aaatgtccat aattcttctt
      421 aattaaagaa tctattctag cttttaagac cggcaatgaa aatggctttt ctacatatcc
      481 gtctactaaa ttagtaaatg catcaatttt atattcttca tcactaaatg cagtcaagat
      541 tagaattggt aaattgcttt tctttctaat ttctttcaac acttctaaac catttataaa
      601 aggtatctga atgtctaaga taaccaaatt tatatcgcta ttaaattttg acaaggcttc
      661 tcttccatct ttagcttgaa taacagtata tccaaattct gaaagatatt cacttattcc
      721 ctctcttatc atattatcat cttcaacagt taatattttc atatatacct ccacttaagc
      781 ctatacacta gatattatac agcatattat ggctctataa tatctagtgt tggtgacacc
      841 ttctgttgcc aatacttttt cttttttcta ataaatgcaa acagacacct tgaaatcctt
      901 tagaataaag ggttctataa tattttgtgt tgttggaaaa tcgaaggcga ttttctacta
      961 acactttttc ttcgtttcaa ctcaaaaaga gactcacttt tggtaaaatt tagtcgacca
     1021 aaacatcacc ctaccaaagg agtcgctcta tggataatca tactagaaaa ttactcgtat
     1081 taacagataa acatttattt tttgatgaag aatggctgat tgaaaaagaa tataaaggcg
     1141 ttcaagcgca gtttattaaa gggagattgg atgactcacc ttcccattgt gaacactgtg
     1201 gatcgattcg tattatccgc aacggttcct atacgacacg tactcagata ttgaaagtca
     1261 aagaaaagtt gactatttta gaattaaaac gtacccgttt tctatgctat gattgtgggc
     1321 agaccttttc tgcgaaaacg gacttagttg atgaacatca tcaactaaca aaggaactga
     1381 agcaggcgat tctcatagaa ctgtacgaaa atcaatcacg taaactaatc gctaagaagt
     1441 acttcgtctc ggatgggacg gtgacacgga tcttgcgtga agcaacgaag cattaccagc
     1501 cacgtatgaa cttccttccg acggtgttgt gtatggatga gttcaaatca atgaagtctg
     1561 tttctggttc catgagtttt atttgtgttg atgggacaac ccatcagcta tttacgatcc
     1621 ttgaagatcg cagactttac aaactaactc aatacttcct gcgctttcct agaaa
//
LOCUS       DAZAOD010000202         1665 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000202 DAZAOD010000000
VERSION     DAZAOD010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.209"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..231
                     /locus_tag="ACHDPO_002930"
     CDS             <1..231
                     /locus_tag="ACHDPO_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFN3370479.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
     gene            390..>1665
                     /locus_tag="ACHDPO_002931"
     CDS             390..>1665
                     /locus_tag="ACHDPO_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFN3370480.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHG"
BASE COUNT          537 a          324 c          306 g          498 t
ORIGIN      
        1 ttaaaaaatc ttcctgaaac acttgatgca caacttcgca cgaaacttca aaacctttta
       61 acgtatgaag aaggtattta caatgctatg atttacccgt attctaatgg caaaatagag
      121 gccaagattc cccatatcaa gacactgaaa cgattatctt atggatttaa atcatttgag
      181 aacatgaaaa tcaggatttt tttgatcaat caattgattc aagtgaaata acaaaaaaat
      241 ctgagacaga aggtcagtcc ttctatcggc tctatacttt ttgatgttgg tgaacttcac
      301 caacatcttt tttgtataaa aaaatataga aaagacaccc tgaaatcctt tagaattaat
      361 ttggctacca attcatagga ggattcaaga tgtctcatac tcagcttatc aaagataccc
      421 taaatattct agacctaaat atctatttcg aggaaaattg tttaactaaa gaaaaataca
      481 aagggcaaat ttgcttgatt tacaaaggaa ctcttctgta caagccagaa gagtgttccc
      541 attgtctttg tgtcgtcccc tctaggatca ttcgttgggg gacgacaacc gttcggttgt
      601 tactgaatga tgtgtctgag tatcgcactt atctggagct gaagaaacaa cgatttaaat
      661 gtaagtcttg ccaaagaaca ttcgtagcgg atacctctgt tgctgaaaaa cactgtttca
      721 ttagtcaaaa agttcgttgg tctgtcattg ctcgcttaaa agagaatact tccatgacgg
      781 aaatcgctcg tcagaaaaat atttccactt cttcggtcta tcgtgtcatg aagcgattct
      841 accgcccatt gaatcctttc aaacagactt tgccaaaggt cttatgcttt gatgaattca
      901 aatcggttcg aagtgttgcc agtgcaatga gttttatcat gatggacgga caaagccatg
      961 cattattgga tattgtcgaa aatcgacgct tgccttattt agaacgctat ttttctcggt
     1021 tttcattagc gactcgtgaa gccgttcaat tgattgttat tgatatgtat gcgccttatg
     1081 tttcgttggt gaaaaagctt ttcccgaatg ctcagttgat catcgatcgt ttccacatcg
     1141 tccaacatat tggcagaact ttcttgaatc atcgagtgaa agaaaccacg gtacgactta
     1201 aaggaaattc ccactctcaa cgagggttag ggaaaaaatt gaagcgctat tggaaactcc
     1261 tacaaaaaga agaagcaaag ttaaactatg aaaaacgggt ttggcgtgcc agttttaaag
     1321 attatttgac tgaaagtgag attgccgatc gactgttagc tgcttgtccc aacttacgcc
     1381 aaggctatca gttataccaa gacattcttt atgcggtaaa gaaaagagat cagtcactat
     1441 ttgaggattg tttaactaga gacattagcg gtctgccaga aacctataca accactttac
     1501 gaacgtttaa aaagtttctg ccacagatcc aaaatgcgct tcactacagc tattcaaacg
     1561 gaccattgga atgcttaaac aaccacatca aagtattaaa acgcaatgcg tacggctttc
     1621 gcaactttta caatttcaaa ctacgaatta tgattcgtca tggca
//
LOCUS       DAZAOD010000203         1629 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000203 DAZAOD010000000
VERSION     DAZAOD010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.211"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            144..542
                     /locus_tag="ACHDPO_002932"
     CDS             144..542
                     /locus_tag="ACHDPO_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFN3370481.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1220
                     /locus_tag="ACHDPO_002933"
                     /pseudo
     CDS             526..1220
                     /locus_tag="ACHDPO_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
BASE COUNT          618 a          237 c          319 g          455 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcagcgataa
     1081 cgttaggtaa agagctacta gatcaagtat tagagatgcc ctcgattgat aaagcagtga
     1141 ggggcttcca agaagattgg gtgcaaactt tccaagcaga aacgattggt gaactaaaaa
     1201 aggtcgctga ttacttctga atcaatttct ccataaaata aacgatagcc ttctcgaaaa
     1261 ctcgaggagg ctatctgacg attcaatatt cattaattta aagtttgggt gactattact
     1321 aactattact tatttctcat ttaaacgatg tattccctaa cctctaatac atccttgtaa
     1381 ctctgaagtt acgccagttt tgaataaatt tcataaaaac aaatgaaaag tgtcgcataa
     1441 aaatatcttt cgtgtttctc tagtataaca gaataagaag aacaagtcca gaagggatat
     1501 ttttagtctt ttttaaaata acttttcagt cgagtttgag tttatgatag ttgtttttga
     1561 agcgatacgg caagtgaaaa aatagggaag catgaaagaa tctacttaat ggcgcattga
     1621 ttcatgtga
//
LOCUS       DAZAOD010000204         1625 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000204 DAZAOD010000000
VERSION     DAZAOD010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.212"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            24..620
                     /locus_tag="ACHDPO_002934"
     CDS             24..620
                     /locus_tag="ACHDPO_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFN3370482.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(678..1160)
                     /locus_tag="ACHDPO_002935"
     CDS             complement(678..1160)
                     /locus_tag="ACHDPO_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370483.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1266..1463)
                     /locus_tag="ACHDPO_002936"
     CDS             complement(1266..1463)
                     /locus_tag="ACHDPO_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370484.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
BASE COUNT          544 a          336 c          255 g          490 t
ORIGIN      
        1 caaatcaaag gagaaatttt attatgacaa cttttactga cactttgaaa aaccgccgtt
       61 caatctatca tctaggacgt aatgtttcac tttctaatga agaattaaca actttgatca
      121 aagaagcaat taaagaaagc ccaactgctt tcaatgctca atcaacacgc gcagttatcc
      181 ttttcggaga tgcacatgaa aaactttggg aaatcactga agaagcactt cgcccattga
      241 ctccagcaga agctttccca aatacacaaa acaaattagc tggtttcaaa aatggttatg
      301 gtacagtatt attcttcaaa gatactgacg tggtaaaagg tctacaagaa caatttgaat
      361 tatatgcaga caacttccca gattggtcag aacaatcaaa cggaatcgca acagctaata
      421 cttgggtagc attagttgat aaaggattgg gcgcaaactt gcaacattac aacccagtta
      481 ttgacgaagc agttgcaaaa gaatggaata tcccttcaaa ctggaaacta cgttcgcaat
      541 tagtattcgg ttcaccagaa acaccggctg aggaaaaaga atacatgaac gatgccgatc
      601 gcttccgcgt atttggataa ttttatttga aataaaaaac agaggttgtg acaaacatct
      661 tgtcgcaacc tctgttttta ttctggatca atcataatat caatctctgc ctcatcgttt
      721 aagcgttggg acaaaaatgg aactaattct tctaatgatg cagaaaattt cagcatcggt
      781 cctcgccatc cgtttcggaa aaaattcatt tttacgattt tagaaccttt tggctgatat
      841 aatacaattt tattgatctc agaaaaagga acaccttttt tgtcaaagct attcaaaaca
      901 agtccttctt ctgtgattcc tctactgtcc aacaaaaaac taataaaaat cattgctgac
      961 aagatccctt ttgccaattc atctgctgta ggatgactga tgagtgtata ccaaatgact
     1021 agtgacacta agaagggtat caccaagtag acccatcgat ttcgcacagt ccgataaata
     1081 atttcttttc gaaccagcca aagaaataaa aacatcacaa caacgaataa aaacaataga
     1141 accgtaaaga atgttaccat gacaactcgc ctcgcttttt cttctccaga aaataggaaa
     1201 agaatactga tttaccttct caaagaaatt ggacttgcag cacgccgcac gtccaattgt
     1261 tttctttatt caaatgtatc atattttgca acaaccatgc ttgctttttc atctaataat
     1321 tcttggtcct ctgcagcaca ttgggcaact ttgaccacgg cgcagtttgt catttttgat
     1381 acaacttcac caatgaccgt ttttgtaaaa ccaattggtt tgcatgcata ttgttctcct
     1441 aaattaatca tttcttccgt catcaaaatc ctcctaaact gctggaactt ttctccacat
     1501 taccactgct atttctttgg agatttaact cattgatttt tatttacagt taaaaatcaa
     1561 ccttacaggc attatagcgt actgttttcg ttttcacaat taaaacagct gttgtattta
     1621 gaaga
//
LOCUS       DAZAOD010000205         1615 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000205 DAZAOD010000000
VERSION     DAZAOD010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.214"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1294
                     /locus_tag="ACHDPO_002937"
     CDS             <1..1294
                     /locus_tag="ACHDPO_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003731151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HFN3370485.1"
                     /translation="LNLSLDLNLIELLISRDTEHKQRKITEEFGVDKWNESFELLFSE
                     NALNKKVNDFLLSNGLNEEEYPTIFEIDYSYALKEEEYQLLAIALESISKDIEDLNGL
                     SELIHLDIREFWKLKLRSYLDKKAEHYRQILYSNANKSGDEILKETFLEKIDRYKDYQ
                     FEISEIPNSVQVDIEKESKKRFPELSVSITDEIDIDGLYDNNVEELVTVAAITIDDFD
                     YYIRGHQKVSSLLYFGIPSRLREDILIFVTKENDVDLNGEKSGISIEGTSTVQTILEP
                     SNSVSRKGKNTRNGERSKRDYDNRNSANDDAGETAEQIAYAELTQNQKLNVIWNTKYS
                     SKSSDRNKQPPNGIVCDMWVHDPENGNMYFEVKSSITEFEMSINEYNSMLDNPDSYEV
                     VLVNRDTKEISRHKFDELDGLKQASSYLFKFKQKRSDG"
     gene            1429..1557
                     /locus_tag="ACHDPO_002938"
     CDS             1429..1557
                     /locus_tag="ACHDPO_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFN3370486.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
BASE COUNT          623 a          211 c          307 g          474 t
ORIGIN      
        1 gttaaatcta agcttagatt tgaatttgat tgaattgtta atttcccgag atacggaaca
       61 taaacaaaga aaaataactg aagaattcgg tgtagataag tggaatgaat cgtttgagct
      121 attgtttagc gaaaatgcgt taaataaaaa agttaatgac tttttgttat caaatggact
      181 aaatgaagag gaatatccta ccatttttga aattgactat tcatatgcat taaaagaaga
      241 agagtatcaa ttgttggcga tagctctaga aagcatttca aaagatattg aggatttgaa
      301 tggattgtca gaattgattc atttggatat tcgtgaattt tggaaactga aattaagatc
      361 ttatctagat aagaaagcgg aacattaccg ccagatttta tatagcaatg caaataaaag
      421 cggtgatgaa atactcaaag aaacattcct agaaaaaatt gatagataca aagattatca
      481 atttgagatt tctgaaattc caaattcagt tcaagtcgac attgagaaag aaagtaagaa
      541 gagatttcca gagctaagtg tgtcaattac tgatgaaatt gacattgatg gcctgtatga
      601 taataatgtc gaagagttag tcacggttgc agctattaca atagatgatt ttgattatta
      661 tattagaggt catcaaaaag tttcttcctt actgtatttt ggtattccgt cccgtttaag
      721 agaagatata ctgatattcg ttactaaaga aaatgatgtt gatttgaacg gagaaaaatc
      781 tggtatctct attgaaggaa catcaactgt tcaaaccatt cttgaaccat cgaatagtgt
      841 tagtaggaaa ggtaagaaca cacgaaatgg agaaagaagt aaacgagatt atgataatag
      901 aaactccgca aatgatgatg ctggtgaaac agcagaacaa attgcttacg ctgaattgac
      961 tcagaatcaa aaacttaatg taatttggaa tacgaaatat tctagtaaat cttcagatcg
     1021 taataagcag ccaccaaacg gaattgtttg tgatatgtgg gttcatgacc cagagaatgg
     1081 gaatatgtac tttgaggtaa aatcatcaat tacagaattt gaaatgtcga ttaatgaata
     1141 taattctatg ttagataacc ctgactctta cgaggtcgtt ttagtcaatc gtgataccaa
     1201 agagataagt cgtcataaat ttgatgaact tgatggattg aaacaggcaa gtagctatct
     1261 tttcaaattt aagcaaaaga gaagtgacgg ttgagtgatt tgtttccaca aacctattca
     1321 atctatcaac tcaaaaatca taaacaacca ttattatagt aggaagatac agagtgtact
     1381 ctcaacgcat atcgaattag tcgcttcatt cgttaaagga gaataaaaat ggaccaaaaa
     1441 gaaaaaatga aagaattgat caaaaagaaa caaggtggag gccgatccaa acaaatggaa
     1501 acacctaaga atgatcgtaa aaacatgaga aaaggcccta aaatctttaa taaatagacg
     1561 tgctaaagaa agactaagaa gtgttaactt ttgttattgt ttcttagtct tttta
//
LOCUS       DAZAOD010000206         1581 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000206 DAZAOD010000000
VERSION     DAZAOD010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.215"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..182)
                     /locus_tag="ACHDPO_002939"
     CDS             complement(<1..182)
                     /locus_tag="ACHDPO_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFN3370487.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="ACHDPO_002940"
     CDS             517..951
                     /locus_tag="ACHDPO_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFN3370488.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="ACHDPO_002941"
     CDS             974..1294
                     /locus_tag="ACHDPO_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370489.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
BASE COUNT          601 a          236 c          342 g          402 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg a
//
LOCUS       DAZAOD010000207         1563 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000207 DAZAOD010000000
VERSION     DAZAOD010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.216"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(60..284)
                     /locus_tag="ACHDPO_002942"
                     /pseudo
     CDS             complement(60..284)
                     /locus_tag="ACHDPO_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(838..924)
                     /locus_tag="ACHDPO_002943"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="ACHDPO_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          551 a          238 c          209 g          565 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg cttttataat
     1081 acgattattt gtaacaaaat gaatattata taattaaaca ctaccatatt taggtagtgt
     1141 ttaattatta gcaaaacaaa aaatatttat tctattctct taacttcaac taagttatgc
     1201 tgcacacctt tatataaatc atatgcaact cattagctag acaaactaca agcatgtagt
     1261 tttatctgtt aattatgtac tacctaaata aagtagttta taattagcaa gtatatatat
     1321 ttaaaaattt aagattaatt tttttatgac ttgtacaaat ttatctgata ttctcttatt
     1381 aagaactacc taatttgggt agttcttatt ttttacattt taagtagtat ttaattgcaa
     1441 tttggtagta tttttttatt atcttattct tagaacggta gtacttaata taaatatagg
     1501 tagtatctaa tttaagtatt aatggtagta tctaaattaa caggtagtat gtaactactt
     1561 taa
//
LOCUS       DAZAOD010000208         1542 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000208 DAZAOD010000000
VERSION     DAZAOD010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.217"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(147..461)
                     /locus_tag="ACHDPO_002944"
     CDS             complement(147..461)
                     /locus_tag="ACHDPO_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370490.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            747..986
                     /locus_tag="ACHDPO_002945"
     CDS             747..986
                     /locus_tag="ACHDPO_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370491.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1348..>1542)
                     /locus_tag="ACHDPO_002946"
     CDS             complement(1348..>1542)
                     /locus_tag="ACHDPO_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370492.1"
                     /translation="VIGEVISKLENCVVICVDEYHDVDRNEILEKCGKVVAKYTHVYE
                     LETTEYLYNYSNKYEHTLVS"
BASE COUNT          538 a          273 c          210 g          521 t
ORIGIN      
        1 attataaact ctagagaaat taattcatcc taacataaaa taattgttca ctcaaaagtt
       61 tttctagaac aattaaaaca gcaggcttca cattcgctat acatttgtaa gaagtaataa
      121 ttcctgtact aaaaggcata attgctttaa ttattttttg acttctcttc aaacacaaga
      181 agtagttgtg taataattgc agaaataagg attccaataa tagatataaa atttgacatg
      241 gaaacgtcta taacattaaa agaataaagt gttgaagaaa gtaaactgat tgaaataacc
      301 cctccgtaaa aaatagtctg tgaatatacc cacttttttt cagaagacgt acttcgtttg
      361 gttctaaaac ctatccctgc atttctactc ttatcaaaaa accaaatatt tagaagtaat
      421 aatattgcta ttattaagat aaaattactg taaaaatcca aaagctatcc tcctagcaac
      481 tatttaaata cccaaaaaaa ttacctctag ataatatcat acctacgttt tcacttataa
      541 attttttcat aaaaaaagcg tttagaggca taatcgttaa tacagatggt aaccaatgta
      601 tctggtttga actgggatat caccctctcc atatatgtat tactaagact aatagatact
      661 ataaaagact tgatagtttt gcattgattt tgcctaatac tgagcatagg tgtatgctaa
      721 acgatactat aaggagtgtg tacataatga aaagaattct gtttatcagt ttatcaaatt
      781 tattgttact tactgcttgt gggacttctg catcaaagaa cataccttca gatacgcaaa
      841 tttcgaatag tatcgattca acaatttcta caaatgagaa aaattctccg gtagaaactt
      901 ccgatataaa agtttctacc tctgcaaaaa acagggtaaa gaaactgtca gcacgtctcc
      961 tttatttcaa acaaactctg aattagcttc ttcatcttct tcagcaaata atgatgatag
     1021 tttcgcgttt actcctaact aaatgcaacc tttacaaatg ctttacgata acaagcctga
     1081 gctaaatgat cctgatatca gttttgcatt ttttgaaatg attggatcgg atgatctttt
     1141 taaaactact agtttgtcta tccgaaaata ggacagttct ggcagtatag gtttttatcg
     1201 agtttctcca ccaggcctcg ttacagagac agattctcta ggcgaacctt ttgaataaat
     1261 caaaaatcat gaacaatcac tgccaactaa ataaagtgcc ttcaaaagct tggtcttctc
     1321 gcttttgaag gcactttatt taaatcttta tgaaactaaa gtatgttcat atttgttgct
     1381 atagttatat agatattctg ttgtttccaa ctcataaacg tgagtatatt ttgccactac
     1441 ttttccgcat ttttctaata tttcattgcg atcgacgtca tgatattcgt ctacgcagat
     1501 cacaacacaa ttttctaatt tactgattac ttctccaatc ac
//
LOCUS       DAZAOD010000209         1534 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000209 DAZAOD010000000
VERSION     DAZAOD010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.218"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..686
                     /locus_tag="ACHDPO_002947"
     CDS             <1..686
                     /locus_tag="ACHDPO_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFN3370493.1"
                     /translation="KEEFAFILTLFNLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKE
                     LVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQT
                     IFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYIVTNSDVHYLIYREALE
                     AVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIDR
                     AIISAVQNK"
     gene            complement(778..1143)
                     /locus_tag="ACHDPO_002948"
     CDS             complement(778..1143)
                     /locus_tag="ACHDPO_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFN3370494.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1140..1505)
                     /locus_tag="ACHDPO_002949"
     CDS             complement(1140..1505)
                     /locus_tag="ACHDPO_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFN3370495.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
BASE COUNT          500 a          305 c          247 g          482 t
ORIGIN      
        1 aaaaagaaga attcgccttt attttgacac tattcaatct ttgtaattat ggtttccatt
       61 cttatcagtt gattgcggaa gactttcaac agctacacca agtgtttatt gacaatactc
      121 ccgaaataaa agaactagtt gctacctttg aatctcactt caatcaagaa ttattcggaa
      181 accaaccgtt cgaacgtgcg ctgattcatc tgatgcgttc ggcttgggat aactatcaat
      241 tattcatgcc agaaaaattt tatcttttaa atgaggaaca gacaaattta tataaagaag
      301 tccagacaat tttttccagc tggtccagcc agttacctta tgatctacgg ttgaatccta
      361 attgcatgcg ggcttttgtg atcgaattga gcggaattct ccgtctgaca aaagaacatc
      421 tgactatcta tatcgtcaca aattcggatg ttcattatct gatttatcgg gaagccttgg
      481 aagctgtaac tactttcgat tttcaagttg caccaacaat ttattcaagt atatctgata
      541 taaagaagta tgcgcagcag tcctcaaacc gggtattatg tgaacgtaca ttatatacac
      601 cagatgcggt ccaatatgaa aatattattc ctatttcgat caatacgatc gatcgagcta
      661 tcatttcagc tgtgcaaaac aaataagggg ctgtgacaaa aatcatgtca cagcctctta
      721 tttgttgaag atgcccattt ctgtaacaat ctcttgatac acgtcaggct cacaacctca
      781 cttattttgg acatctacgg gtccgatctc tttatttaaa aaataagaaa tgatggttcg
      841 gataactacc aacgccgcta gttggaaaat atcctgcaag gtaggtttga taatcgattc
      901 gatgatccca gctgaaacaa gaatttccaa acttagaagt atatagcctc ccaacatctt
      961 tttaatagca ttgttctcgc tgactcggtc gctttgcact tttgtatgga caaataaata
     1021 tttcaaaaaa tccttgattg atagacaaac accccaaacc aataaacaga tagcaaagat
     1081 atcaagtccc agtacaagtt tttcgaaata tggaagaaga aactgcatca actctgtcgt
     1141 catcctacct ctcctcttct ttgtttttct ttgtcttcta tttcctgatt caagaaataa
     1201 gaaatgactg ttcgaatgat aataataagt gcaagcttca aaatatctgt ccaagtcggc
     1261 ttgataactg actcgatgat atcagcaacg actagtactt ccaagcttaa caaaatataa
     1321 cttgctagca gttttcttgt atctgcatta cgagtattac gttctgcata gtttttcttg
     1381 acatgagacc aatcaaaaag tttgaataga acaagaacga tcccgacaat taagataccg
     1441 atagaacaaa tatttaaaat agcaatgatc cattctagaa attcaattaa atttgagcga
     1501 aacatatacg ctacctactt tcttttaatt tgtt
//
LOCUS       DAZAOD010000210         1531 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000210 DAZAOD010000000
VERSION     DAZAOD010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.219"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            75..>1531
                     /locus_tag="ACHDPO_002950"
     CDS             75..>1531
                     /locus_tag="ACHDPO_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370496.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVSICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNR"
BASE COUNT          552 a          212 c          282 g          485 t
ORIGIN      
        1 cagtataggt gaaaagatga actttcatct gcatatcaag taattggtat gaggcatttt
       61 ttgaggtgta ggatatgaag ttggattacc ttatagaaga ggaagataga gaaaaactgc
      121 tgctagctag atatttagaa tttgagaaaa agaattatgt agtgctgcct aagttatatg
      181 aaacattagg tttgtctaaa tttaaaacaa gaaattatat catagaatta aataaagaat
      241 ttactgaatt caaaacaaag ccagagatcc aaatttcaga agaagcagag atccatgtcg
      301 aacgtctgaa tttgacggat atcaaaaatt taagaagaat ctactttcaa cgatcaaaaa
      361 ttgctcgact gttaacggag atcgtggatt caaaagtaac gatcgaaaaa tttgcagaga
      421 atcatttttt aagcatatca agagcctatg taaaaagaag agaattagtc tcttttcttg
      481 aacagcatca aataaagtta aagaaaaaca tattagttgg ggaagaaata aacatacgga
      541 acgtattatt tggggtatat ttcggggtct ttaatggttt ttctatgcca tttagagaaa
      601 gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga atatctgttc aatttaaaac
      661 tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac tattagtttg ttgagggcct
      721 atgggaatca accaatcgga aaacgtttct tttcagatga atactttaag agctcagaag
      781 gaatgaagat catcaaggat ttatcacata tttcttttct tcatatccct aaagagcaga
      841 tcattgatga gatttcttat atcatgttgt ttttgatcac ggaagaagaa tttgaattag
      901 atggcgcatt tggacttgcg gaagctcatt ttcatgatat ccacatgatt agtcaaaaaa
      961 tgtcagtgga attgattgat caattaccat tttcgattga aatctctgaa gaagaaagac
     1021 tatatatacg aaaagaactt cgtatgggta tgatgcatgt caatcgaaaa aattggatat
     1081 tcgactttga gatgactagc tttacgtcta aaaagcagct acagtttttc ttcgagacgt
     1141 atccaatatt cagtacagca atccaaaagg tcatacaaga gaataaacgc tatttcttgg
     1201 gaaaagatga acgtttcatg attcgcttat tttatgatta tctcttttta ttggtcagta
     1261 tttgtccggt atcatatttt gaagcaccga ttcatgtctg tattgatttt tcgcaaggat
     1321 ctgcttatac cgattacatt atttctcaag tgaaaggatt taaaaattac aatattgtga
     1381 ttgagagtcg aatcacttct cgtacgaata tttatttatc tgattgttta cttgaaaaat
     1441 ttaataaaga acagataatt tggaaaaatc caccgactcc agatgactgg gaatattttg
     1501 gaaataccat catcagagaa aaaaatagac a
//
LOCUS       DAZAOD010000211         1505 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000211 DAZAOD010000000
VERSION     DAZAOD010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.220"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            776..1162
                     /locus_tag="ACHDPO_002951"
     CDS             776..1162
                     /locus_tag="ACHDPO_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFN3370497.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1256..1447
                     /locus_tag="ACHDPO_002952"
     CDS             1256..1447
                     /locus_tag="ACHDPO_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370498.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
BASE COUNT          560 a          232 c          211 g          502 t
ORIGIN      
        1 tgaattcgga attaaaaacc acgataggta actttaaaca aacatgaaga gactttaata
       61 agacttcttt atctgaaaac acttttgttt ctctctttcc tttctacatc attaaatagt
      121 attttatacg ttatctaaaa tactattcct ctgtcaaaat aagctaactt acttcattat
      181 aaaatatcca cttatcgctt tcatgtatat tccaccgtaa aaagtacatt ttatcaccga
      241 gaactcatca tttttcatca tgatgaatac tatttacata tatctagttc aaagacaata
      301 attattatga tccgttatta tctaagcact atacagataa taggaatttt tcgtttctaa
      361 atattccaat ttgggaatcc aataaaaatt ttcgttcaaa tacgtgtcta ttcgaactct
      421 tttctagttg ttaattatga agggggaaga aataaaaaat acaatctata cacgaataag
      481 aatattatcc aaaaggaggt tttagaaaag atttattata cgtaaaaagc tcaagacatt
      541 ttcttagcca taaggacatg tttgatattt aagaagatat atgaattttc ttttctaagt
      601 ataaagataa ctatccatta tcaactaaaa aaacattttt gaaaataaac atcagcagtc
      661 ctatcaatgc atgtgagctt atagaagtta ttcgcagcgc agcataattg cattagcttc
      721 ttttcgtgtt ttttgcctct tttcccttta aatcttaatg gaggaggtgt gcaatatgtc
      781 agataacgac gaacgcgtaa atgcccagtt gattcgattc tttgaaaagg tcattttgaa
      841 caccgctaat acttattata aaaaacaaga agaaattcaa aaacatgaac aacttgatca
      901 actcccacca tatttgttta ctaaagatac tataaaattt aaacaaccga ttaatgtttt
      961 aaatgtgact ctccttgttg aagatataaa attagcaaaa atccttcctt tgttgaaaga
     1021 acctgaacaa atttttctta tcgaaaaatt tatctttgat aaaactgata aagaaattgg
     1081 aaaggttctg gggattacaa gacagggtgc gacaaattta aaacatcgac tttacaaaaa
     1141 aattcaaaaa atgctggttt aatatctgca taataactaa ttttgtatgc ttctttgctc
     1201 gttctcctcc ttcccaaaga aatagattat aagtccatgg gaagaaggta gatttatgaa
     1261 ttctttaaaa gaagatttca ttttagcaaa ggctggaaat gaagaagctg ttgaggcaat
     1321 tctcaaaaga tttagctctt tgattcataa gcaatcctgg agaactggaa aatatgatca
     1381 agattgttat caagaatgta tgcttgcaat atatctagct atctcgaaat tcgaaattaa
     1441 agaataactc aactaaggga gtctgtgaca taagtaaaaa gatagtttca aatttcgaac
     1501 aataa
//
LOCUS       DAZAOD010000212         1503 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000212 DAZAOD010000000
VERSION     DAZAOD010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.221"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1458
                     /locus_tag="ACHDPO_002953"
     CDS             <1..1458
                     /locus_tag="ACHDPO_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFN3370499.1"
                     /translation="QQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDTVAN
                     GGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIVLAL
                     PFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGALLA
                     PLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEERKGF
                     IRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVTAEE
                     KPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNPIFI
                     FILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPLWLL
                     GSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFYTPG
                     TESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          408 a          289 c          318 g          488 t
ORIGIN      
        1 cagcaagaca agggcttctt cgggcagccg aagggattgt caactttgtt cttcactgag
       61 atgtgggaac gatttagtta ttacggtatg cgtgcattac ttatctatta tatgtacgat
      121 acagttgcca acgggggact tggattacca cgagcaacag cattagctat catgtcgatc
      181 tacggatctt tgatctacat gtctagtatc gtcggcggat gggtatctga ccgagtgtta
      241 ggagcaaaac gcactgtatt cttcggtgga gttttcatta tgcttggcca catcgtcttg
      301 gctttaccat ttggtgtaag tacattgttt gtttcgatgg cattgattat tatcggaacc
      361 gcctttttga aaccaaatgt ttctggcatg gtcggacatc tttattcaaa gactgacttg
      421 cgaagagatg caggattttc gattttttac atgggtgtca acttaggggc attattagca
      481 ccactaatcg ttggtacaat cggtcaagaa tataactatc atttagggtt ctctttagct
      541 gctattggga tgttctttgg attattacaa tacatcatcc aaggacgcaa gacattagac
      601 ggagtgggta caacaccgcc gaatcctttg acaactgaag aacgtaaagg attcatccgt
      661 aacttgatca tcgcacttgt tgttatcgct gcagtattcg gcggggcaca actaactggt
      721 catctgacaa ttgacttttt tgtcaataca atcagtgtat tggggattat cttaccgttg
      781 tattacttta tcaaaatgct gacttcaaaa gatgtaactg ctgaagaaaa accaagagta
      841 tgggcttata tcccattatt ccttgcagca atcattttct ggtcattaca agaacaaggt
      901 tcatctatct tagctttatt tgctagtgaa cgtacacaat ctacgctatt tggtgtaacg
      961 atccaagcaa gctggtatca atcattgaat ccaattttca tctttattct gacaccagta
     1021 ttcgtaacga tgtggacgaa acttggtgaa cgtcaaccat ctacagtagt gaaattctct
     1081 cttggacttt tatttgcagg attatcgtac ttgctattga tgttgccggg tatgctttat
     1141 ggtacaagtg gaaaagtaag tccattgtgg ttgttgggaa gtttcttcat cgtggttatt
     1201 gctgaattgt gtctttcacc agttggtttg tctgtgacaa caaaattagc accacgagca
     1261 tttgaatcac aaacaatcgc tatttggttc ttagctgatg cttcttcaca agcaatcaat
     1321 gcacaaattg cacgcttcta cacaccggga acagaatctg cttacttcgg tattatcggt
     1381 gcagtagcaa tcgtcggtgg tatcttgcta tttactgtga aagaaccaat caaaaaacta
     1441 atgggctcta ttcattaatc aatgaacata aaaacaggaa ttgcttattt gcagcagttc
     1501 ctg
//
LOCUS       DAZAOD010000213         1500 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000213 DAZAOD010000000
VERSION     DAZAOD010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.222"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            21..443
                     /locus_tag="ACHDPO_002954"
     CDS             21..443
                     /locus_tag="ACHDPO_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370500.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            453..656
                     /locus_tag="ACHDPO_002955"
     CDS             453..656
                     /locus_tag="ACHDPO_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370501.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            867..1451
                     /locus_tag="ACHDPO_002956"
     CDS             867..1451
                     /locus_tag="ACHDPO_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFN3370502.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          533 a          218 c          282 g          467 t
ORIGIN      
        1 tgatttcgag gtgatagaca atgaaaaata agtttatttt atctttaggt attttaacta
       61 ttggaattag tgtaactgga actacaattc ctacatttgc tgatagtaca aatgaaccaa
      121 ctactgtagt agataataac caagaattaa ctcctttaga taggaacgga atagccattg
      181 gtaacccaac taacgactta actgttactg aaaattattt aatagtttct ccattacttg
      241 ctcgagcagc ttctaaaacg atacgagtga caggaacgat gatttttgat aaagttggtt
      301 ggccttctag acctcctcaa tcacggaatt ggaaagaaaa aagaaatggt tattggtact
      361 atggaaaatt gtatttacaa agttataaat cagctggaaa caattggatt gcgacttatt
      421 caggaacctt aactagaaag tagggatttt ttatgccaga atttgtgaac acaccaaatt
      481 tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc gaaagaagaa tcagctttac
      541 aagttcagcg aactttacag gagacacaaa aaattcaaaa atcaatttct aatctagaag
      601 attctgaaga aaaaagaaaa aaaagagacc aaaaaacata tcaaaaagaa aaataatgat
      661 tttaaaaaaa gagtgtctag tcgacattct ttttttctaa ttgaaagtgt tcataaaatc
      721 acccatttct ggacactttc tttttttgct ttatttttca aaaaaacaat tcatttcatg
      781 ttcataaacc cataacaata tctatgttca gttaaactat atggataaag ttatgttaca
      841 ataaaattaa tgaaggagtg atttttttga aaataggata cgcccgggta tctactggtt
      901 tacaaaattt ggatttacaa gaagacagcc taaataaatt tggttgtgaa aaaattttta
      961 ctgatcatat gagtggggca aaaagtaatc gaccaggatt agaaatggcc attgattttg
     1021 ttcgctctgg cgatacactt gtcgtttggc gcttagatcg tttaggtaga aatatggaag
     1081 atttgatttc aatcgtcaat cgactgaatg agcgtggtgt gagttttcat agtattcaag
     1141 aaaatattac gatggacaaa tcaagttcta caggacagct catgtttcat ttgtttgcgg
     1201 catttgcaga atttgagcgt aatttgatcc tggaacgatc cgcagcagga cgagcagctg
     1261 ctcgtgcaag aggacggttt ggtggtcgtc ctgaaaaatt gtctgaacaa gatttggaat
     1321 tactgaagac tttagtggat agcggtacac ctattaagac tattgcggaa cggtggaacg
     1381 tctcaagaac caccatttat cgttatttgg caaaaatgga ggagaaaaat ggaaagacaa
     1441 attctcatta gtttttgtca tttaatgctg aaaatttttg ccatttatct agaaaagtga
//
LOCUS       DAZAOD010000214         1491 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000214 DAZAOD010000000
VERSION     DAZAOD010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.223"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(429..1043)
                     /locus_tag="ACHDPO_002957"
     CDS             complement(429..1043)
                     /locus_tag="ACHDPO_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFN3370503.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT          490 a          280 c          245 g          476 t
ORIGIN      
        1 ttatttctat tagaaaaagg tatcctgttg gacaattttg ttatatcagg taaacttcat
       61 tgcaataatg ataacaaatg tactataatt actttgtaaa gagttttggg gaagactctt
      121 tcatcaacgt gtattaagag acaagaaaga atccatatgg attctttctt gtctcttttt
      181 ccactacttt ttatttttct gacactacat attcttataa ctcatttctc ataactgtga
      241 aacaacttat aaaaataaca aactttaaac aaaacaagct taaaatcaaa gatgatccat
      301 cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc ctcattaata atcgttttct
      361 ttttttcaaa cgctccattt ttatgtggaa cattattttt ttaaggaact ttgtcaacat
      421 gtggataact attttccact tgtgtcctgg actagctgtt ttgctgtaaa atacaaaact
      481 tgctgcagca aaaagatcgt tgcaagagag gctgttccgc agatcgctgg atctagattt
      541 ggcaaagtca agactgcatc atgtaaattg gcgtggttgt ccaaaaccaa atcagcaaat
      601 tcaaataatc gcaaaccact gctatgttgc gatttgatac ttcgtgacaa atcaaatcca
      661 gtaacaatga ttaatggatg accattttct ttgatccact gagctagttc gatgattgcc
      721 gggtttcttc cttcattcga aagaagaaga aaaatgtctt ctgatttgac agaaagctga
      781 tcaataattg cctgtcctgc accttctagc gtttcataga cacctccggc tggattttca
      841 atcaatatac ttggtacaag atccggggtt tgatcccaaa attcaaatgc tacaccactt
      901 agtgtgcggc tagcatatat ctgcaatcta ccaccttgat taatttgttt cgcgatccaa
      961 gtgccagctt gaagcatcag cggctcttct atccttaatt tctcttccaa ttggtgataa
     1021 tagtcaaaat aacataaact catttatctc tcccgcctag ctatacttga catgaataga
     1081 aacagctgcc taatctaagg aagtacataa aaaaacagta gttagacagt aacacatgtg
     1141 gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat acgcccaata ccttgacata
     1201 gcaaataaaa caacgtgcag accatggaaa atatctacat aggggtagaa ttttcaccct
     1261 agattaggta caataaatta ggtcgatgca ctgcattgac tatggcaaaa tgatcggtca
     1321 gggtgtatgt gtgtgactgg tcattccctg attcttagcg ccaactaagg gtcagggagc
     1381 ctttttttat tcagctgttt ctatctgaat ttattgtaag taatctctta tccaagtgca
     1441 agcaagaaaa tacaaaaaaa cattggtatg atttatatat atataaataa c
//
LOCUS       DAZAOD010000215         1480 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000215 DAZAOD010000000
VERSION     DAZAOD010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.224"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            64..972
                     /locus_tag="ACHDPO_002958"
     CDS             64..972
                     /locus_tag="ACHDPO_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFN3370504.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1480
                     /locus_tag="ACHDPO_002959"
     CDS             972..>1480
                     /locus_tag="ACHDPO_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370505.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          529 a          197 c          316 g          438 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt
//
LOCUS       DAZAOD010000216         1470 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.225, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000216 DAZAOD010000000
VERSION     DAZAOD010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.225"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1235
                     /locus_tag="ACHDPO_002960"
     CDS             <1..1235
                     /locus_tag="ACHDPO_002960"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFN3370506.1"
                     /translation="QLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKKLNDV
                     EVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERRFFSV
                     FDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMNLRNG
                     DTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADFAFLL
                     HGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGTSIPT
                     TVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYAHLAN
                     FDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAISSLQT
                     TPENEAWLQGALEVFKHE"
     gene            1228..>1470
                     /locus_tag="ACHDPO_002961"
     CDS             1228..>1470
                     /locus_tag="ACHDPO_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFN3370507.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
BASE COUNT          514 a          245 c          313 g          398 t
ORIGIN      
        1 tgcaattggc atctacctac aatcaattta atgggttatt tgatgatgtg gatctccaat
       61 caaaaaaact aggaacagat gagcaacaac gaaatgtgac gattaccgaa gtcattaaga
      121 aattgaatga cgtggaagtt ttaggtcacg atggggacgt gatcggggat gcttatgaat
      181 ttctgatcag tcaatttgct tcagaagcag ggaagaaagc cggagaattt tacacgcctc
      241 atatggtttc tgatatgatg gcacaaatcg tgacgttgga tcaaaaagaa cgacgattct
      301 ttagtgtttt tgatccaacc atgggttcag gttcattgat gttaaatgtg cgtaactact
      361 taactcaccc agataacgtt aaatatcatg ggcaagaatt aaatacaacg acatacaatc
      421 tagcaaaaat gaacttgatt ttacatgggg tagatgccga agaaatgaat ctccgcaatg
      481 gggatacgtt gaataaggat tggccaacag atgaacctta cacatttgat gcagtagtaa
      541 tgaacccacc ttattcggct aattggtcag cagatacgac cttcttagac gattctcggt
      601 ttaatcgtta tggaaaatta gcgccaaaat ccaaagcaga ttttgcgttt cttcttcatg
      661 gtttctatca tttgaaggaa acagggacta tggccatcgt cttgccacac ggagttttat
      721 tccgtggcgc tgcagaaggg gtcattcgtc aaaaattact agaagacggc agtatttatg
      781 ctgtgatcgg tatgcctgcg aacttgttct tcgggacatc gattccaacg acggtgattg
      841 tattgaaaaa gaaccgccaa actcgagacg tattattcat tgacgctagt cgagaatttg
      901 tcaaaggaaa aaatcagaat aaattatcgg aagaaaacat tcaaaaaatc ctcgaaacct
      961 atgctgaaag aaaagatgtc gagaaatacg ctcatttggc aaactttgat gaaatcaaag
     1021 aaaatgacta taacttaaat attccacgct atgtagatac gtttgaagaa gaagaaccaa
     1081 ttgatatggt tcatgtcgga aatgacatca agaagatacg acaagaacag caagtgctag
     1141 aaaaagaact tttagaagct atctcttccc tgcaaacaac acctgaaaat gaagcgtggt
     1201 tacaaggtgc gctggaggtg ttcaaacatg agtaatgata tacaaccaga aattcgtttc
     1261 ccaggattta cggaagcttg ggaacagcgt aagtttgaat gcttacttga taaaaaagat
     1321 ggagtaagga ggggaccatt tgggagtgcc ttaaagaaag aattctttgt atctaatagc
     1381 aattttgttg tctatgaaca acaaaatgct atttatgata attacgaaac aagatataaa
     1441 attactgaaa aaaaatataa tgaattaatc
//
LOCUS       DAZAOD010000217         1456 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000217 DAZAOD010000000
VERSION     DAZAOD010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.226"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..675
                     /locus_tag="ACHDPO_002962"
     CDS             <1..675
                     /locus_tag="ACHDPO_002962"
                     /inference="COORDINATES: protein motif:HMM:NF025017.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFN3370508.1"
                     /translation="IAKKEKCDYILLLDQDTIIQKNLSLKLLEEFTNIEAKDKDIGII
                     VPNYFENSNDESVSFTCKNERGRYVKKHFASTSGSMKIAFANSSGMFFKSELIDDVGN
                     MKDEFFIDQIDVEFCKRVANNGYNIYVTNQVYFYHHVGDGENLKIGSKKIKIDNHNST
                     RKYFIARNSTLVKRMYKSDKEFSRLMNKRLLKFFIAIAFETDKLSRFRAAIRGVRDGY
                     RGVIGD"
     gene            647..>1456
                     /locus_tag="ACHDPO_002963"
     CDS             647..>1456
                     /locus_tag="ACHDPO_002963"
                     /inference="COORDINATES: protein motif:HMM:NF026247.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpsG family protein"
                     /protein_id="HFN3370509.1"
                     /translation="MDTEASLEINQEKSVSQKKWSTSNKILSGVLLLIMWIIMAFNTQ
                     NADYYAYSVLYNGIAQFGMDFSSDSIEPGFRAVMYVCTFISSQYQIFLLIISTVLLSA
                     LLYVIRLFTTNVFLVLFLFFIFGFTSQAIQVRMFSALIFILLAFYHLTKLRGSKAIFK
                     YIFFILVAGLFHNLAYFYLPFFIVKINKKITGYVTILSLLLFSIGQSYISSIFINTKY
                     DAYFDRNSTSISHVVMFALFFSANLFLVHKLSKMNIYEKKSYQLKLIYIFYQ"
BASE COUNT          493 a          190 c          242 g          531 t
ORIGIN      
        1 attgccaaaa aagagaaatg tgattatatc cttttactag atcaagatac catcatacaa
       61 aagaatcttt ctttaaaatt attagaagag tttaccaata ttgaagcgaa agataaggac
      121 attgggatta ttgttcccaa ttactttgag aatagcaatg atgaatctgt ctcttttacc
      181 tgcaaaaatg agagagggag atacgtaaaa aaacactttg cttcaactag tggttccatg
      241 aaaatagcat ttgcaaattc ctctggaatg tttttcaaaa gtgaattaat tgacgatgtt
      301 ggaaatatga aggatgaatt ttttattgat cagattgatg ttgaattttg taaaagggtt
      361 gcaaataatg gctataacat ttatgtaaca aatcaagtct atttttatca tcacgttgga
      421 gatggagaaa atttaaaaat aggatcaaaa aaaattaaaa tagacaatca taattcaaca
      481 cgaaagtatt ttattgcaag aaattcaaca ttggtgaaaa gaatgtataa aagtgataag
      541 gaattttccc gccttatgaa taaaagatta ttgaaatttt ttattgcaat agcttttgag
      601 actgataagc tcagtagatt tagagcggct ataagggggg ttcgagatgg atacagaggc
      661 gtcattggag attaatcaag aaaagagtgt ttcacaaaaa aaatggagta catcgaacaa
      721 gattttgtct ggggtgctac ttttgataat gtggatcatc atggcattta acacacaaaa
      781 cgctgattat tatgcatatt ctgtcttgta taatgggata gcacaatttg gtatggactt
      841 tagttcagat agtattgaac cgggattcag agctgttatg tacgtatgta cctttatttc
      901 cagtcagtat cagatttttt tattgattat ttctactgtc ttactctcag ctttattgta
      961 tgtcatcaga ttattcacaa ctaatgtttt tttagttttg ttcttgtttt ttatttttgg
     1021 ttttacttca caagcaatac aagtacgtat gtttagcgca ttgatattca tattactagc
     1081 tttttatcat ctaactaaat tgcgaggcag caaagctata tttaagtata ttttttttat
     1141 cttagtggct ggactgttcc ataatcttgc atatttttat ctcccttttt ttattgtaaa
     1201 aattaataaa aagattactg gatatgttac aatccttagc ttgctcctat tctctattgg
     1261 acaaagttat atcagttcaa tatttataaa tacgaagtat gatgcatatt ttgatagaaa
     1321 cagtacatcg atttctcacg tagtgatgtt tgctctcttt ttttcagcaa atcttttttt
     1381 agttcataaa ttatcaaaaa tgaatattta cgaaaaaaaa agttatcagc ttaagctcat
     1441 atatattttc tatcaa
//
LOCUS       DAZAOD010000218         1422 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.227, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000218 DAZAOD010000000
VERSION     DAZAOD010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.227"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="ACHDPO_002964"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="ACHDPO_002964"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFN3370510.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          497 a          184 c          236 g          505 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctattactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctggactaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatacta ta
//
LOCUS       DAZAOD010000219         1411 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.228, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000219 DAZAOD010000000
VERSION     DAZAOD010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.228"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..322)
                     /locus_tag="ACHDPO_002965"
     CDS             complement(<1..322)
                     /locus_tag="ACHDPO_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFN3370511.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAG"
     gene            complement(304..1278)
                     /locus_tag="ACHDPO_002966"
     CDS             complement(304..1278)
                     /locus_tag="ACHDPO_002966"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFN3370512.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
BASE COUNT          458 a          262 c          180 g          511 t
ORIGIN      
        1 tcccagcaat aatttgaatt ctattgttgt tcaactgttt aatagaaaca ttattaggtg
       61 ttcctccaat taaatccgtt aaaataatta gaggttgcaa atgatgctga ctaattattt
      121 ctttcatact ctcctcaaaa tcatctggac tagtattttc tttaaatgga acagcactaa
      181 tacctgtggc gtcattcatt aaaattaatt ttgttgcctt taaataaccc tcacaaaggg
      241 tagaatgtgt tgtaatcaca atgtgaaata attgatttgc catcttttgc aacctcctat
      301 taattaatat ttcatttgcc acatatagcg tctaacatct aaggaatggc ctctttcaaa
      361 agcaatcgct tctaccattt ggcgaataac aacgccacta agtacagctg caatatattc
      421 tttcgctaca ctatctatag attctaagtc aaaatcagct tggtctaaaa ccattaattt
      481 attactgaat tttttagtga agtcttctac ccgttgatct aaaaatcttg tatctccaat
      541 acttttcact aagatgaatg gtacatcata atcagtgatt tcaaaaggac catggaaaaa
      601 ttccccagaa tgaatagcat tagaattaat ccattgcatt tccatgaacc agcaagctgc
      661 tgtggagtaa atttctccgt aattgatacc gctaccaatt gtgtaaataa ttttatctcg
      721 tttttggttt ttaccccatt ctttagcagt tatttcaaat ttgctctttt cagcaataac
      781 aagatcattt aacttatcaa attcattcaa gcaagtttcc cattttttag agccatctaa
      841 aacaagtaaa atattaaata ataaaccata aagaattcct ttatttaaat cactagcatc
      901 aacatcttta ccccaatcat agtgaacagg atattcagct gcttcccata gaggagatcc
      961 ttcttcatta gataaacaaa tagtcattgc tccaaattct cttgcttttt ttgttgcttc
     1021 tacagtttct ggtgttgtgc cagaatggga acaagtgata actaaagaat tttcagataa
     1081 tccttttggt atagcatagt taaattcgtt agcagtataa acatgacaag gtacagttaa
     1141 ttctttatca aatagatatt gaccagccat taaaacggct tgtgaacccc cacatgctgt
     1201 aaaatataca tgatcaattg tcttttcctt taacgctgcc attgctgttt caatctgttc
     1261 tttgtgtagt tgtctcattt ctttatccct cactctaata agtattataa agtcatataa
     1321 ctttacaata cctattatct atgaaattgc tttattttgc aatactattt ttcaaaaaaa
     1381 tttttttata acaattttat ataataaaat g
//
LOCUS       DAZAOD010000220         1364 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.229, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000220 DAZAOD010000000
VERSION     DAZAOD010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.229"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>1364
                     /locus_tag="ACHDPO_002967"
     CDS             82..>1364
                     /locus_tag="ACHDPO_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFN3370513.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAZAOD010000221         1360 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000221 DAZAOD010000000
VERSION     DAZAOD010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.230"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1095)
                     /locus_tag="ACHDPO_002968"
     rRNA            complement(<1..1095)
                     /locus_tag="ACHDPO_002968"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          304 a          376 c          256 g          424 t
ORIGIN      
        1 cctagttgtc tgtgcaaccc cacatccttt tccacttaac atatattttg ggaccttagc
       61 tggtggtctg ggctgtttcc ctttcgacta tggatcttat cactcacagt ctgactcccg
      121 gatatgaatg aatggcattc ggagtttatc tgaattcggt aacccgagat gggcccctag
      181 tccaaacagt gctctacctc catcattctc aattccgagg ctagccctaa agctatttcg
      241 gagagaacca gctatctcca agttcgtttg gaatttctcc gctacccaca cctcatcccc
      301 gcacttttca acgtacgtgg gttcggtcct ccagtgcgtt ttaccgcacc ttcaacctgg
      361 acatgggtag atcacatggt ttcgggtcta cgactacata ctcaaacgcc ctattcagac
      421 tcgctttcgc tgcggctccg tctcttcaac ttaacctcgc atgcaatcgt aactcgccgg
      481 ttcattctac aaaaggcacg ccatcaccca ttaacgggct ttgacttgtt gtaggcacac
      541 ggtttcaggt tctatttcac tccccttccg gggtgctttt cacctttccc tcacggtact
      601 ggttcactat cggtcactag ggagtattta gccttgggag atggtcctcc cggattccga
      661 cggaatttct cgtgttccgc cgtactcagg atcctcctag gtgtcttcca catttcgtct
      721 acggggtttt taccctcttt gactgacttt tccaagtcat tcgactatct gaaagaacta
      781 ccatattgga gtcctacaac cccaacaagc aagcttgctg gtttgggctt ttcccgtttc
      841 gctcgccgct actcagggaa tcgaattttc tttctcttcc tgcaggtact tagatgtttc
      901 agttctctgc gtctacctcg aatgtgctat gtattcacac aatcgtaaca tcctattaaa
      961 gatgttgggt tcccccattc ggaaatctct ggatcatagc ttacgtacag ctccccaaag
     1021 catatcggtg ttagtcccgt ccttcatcgg ctcctagtgc caaggcatcc accgtgcgcc
     1081 cttattcact taaccttatc aaccttacgg ttgggttttg atccttcttc tagcgataga
     1141 agttagatca agaaaataag caattgaact tattaaaaaa ctctatccag ctcacaaatc
     1201 agcctgtacg gcaaaaagat cgatcgtctc ataaaatcaa agattttatg gccgtccgcc
     1261 tattttgctt caggctaaac aatttgttca gctttcaaat tcaacgcggt gttctcggtt
     1321 tgtattactt acatttactt caaatatcca gttttcaatg
//
LOCUS       DAZAOD010000222         1355 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000222 DAZAOD010000000
VERSION     DAZAOD010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.231"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1355
                     /locus_tag="ACHDPO_002969"
     rRNA            <1..1355
                     /locus_tag="ACHDPO_002969"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DAZAOD010000223         1292 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.233, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000223 DAZAOD010000000
VERSION     DAZAOD010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.233"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..314
                     /locus_tag="ACHDPO_002970"
     CDS             <1..314
                     /locus_tag="ACHDPO_002970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370514.1"
                     /translation="AKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQK
                     VFNCYKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFT
                     K"
     gene            complement(639..785)
                     /locus_tag="ACHDPO_002971"
                     /pseudo
     CDS             complement(639..785)
                     /locus_tag="ACHDPO_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            1024..>1292
                     /locus_tag="ACHDPO_002972"
     CDS             1024..>1292
                     /locus_tag="ACHDPO_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFN3370515.1"
                     /translation="MNKKIVVSGLIIGGLVLAGIAGKNFADDILLWGGEDNIEQINHN
                     LESLDKALENKEQNISSLNSRLSSNNQELEQAKANVEEYKQKVLT"
BASE COUNT          462 a          179 c          246 g          405 t
ORIGIN      
        1 aagctaaagg tgaaaagctt tcagtggaag aagtagaaaa acgagctgta aaacataatt
       61 tggtttgcga gacaagggaa caagtaatta aagaaataaa atcattatct gaagatatgg
      121 taaaatatca gaaggtgttt aattgctaca agaaatatac acaagaatcc tatgtaatgc
      181 cacttaatat ccaaacgatt agtaaaaata gaattagaag aattaacaag tttgatcctt
      241 ctggaaatat gaaggcacct ggaaatgtcc tcaatgaagt agatgaaagt ttaaaaaaat
      301 attttacaaa gtaaacgata tttttgttga catttttctg ttcgttagtt accatgtagt
      361 tatagaagga cgtaagcgcc tatttttaat gtacacatcg ggacgtatgc gcccacatag
      421 aaacatagtt gagagacatc tatatggtgt ctcttttttt attaatatgc aaaaaagtct
      481 agttttttca ataatattta tgtaataata aattagccac cacaacaaag aatgaaatcc
      541 attattatct agtctagtcc attctttttg tttgcagtat ttgtgatggc tttccgtacc
      601 cttagctcag ttggtcagag cagacggctc ataaccgtcc ggtcgtactt ctcgtaatcc
      661 aggaaggccg tcagctccgt ccgcagtagc gtgtttacgg ccagctccag atgggagcgg
      721 aataactcgt tcaaatcacc tttggtggct agagtctgca ggagttctgt aataaaatcg
      781 ttcataggga agtcctcttt tctgtgaatg ggtgtggtaa ctttattcta cagaagggac
      841 ttcctttttt ctatttacac aaaatatttt atactctcaa atgtttgtat gcagttacat
      901 ctgactttat tcgaattaag gaaaagattt ataaaaataa aataaaaaaa tatatattta
      961 aattgactta ttgtgaaatc attaactata attagttcag tttatgttaa ggagaatgat
     1021 gatatgaata agaaaattgt agtaagtgga ttaattatag gtggattagt gttagcaggg
     1081 atcgcaggga aaaactttgc cgatgacatt ttgttatggg gtggagaaga taatattgaa
     1141 caaatcaatc ataatttgga gtcattagat aaagcactag aaaataaaga gcaaaatatt
     1201 agtagtttaa attcacgatt atcttcaaat aatcaagaac ttgagcaagc aaaggctaac
     1261 gttgaagaat ataaacaaaa agtgttgact tt
//
LOCUS       DAZAOD010000224         1237 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.234, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000224 DAZAOD010000000
VERSION     DAZAOD010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1237
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.234"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            129..1169
                     /locus_tag="ACHDPO_002973"
     CDS             129..1169
                     /locus_tag="ACHDPO_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFN3370516.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          499 a          177 c          204 g          357 t
ORIGIN      
        1 ctgattttag gtagtattta attaaaaaac agttttaatg cgtttgcatt ttttatttat
       61 ctttgctatt ttcgaaaaga gtaggtaatt ttacataaat aaaacaacgt gaaagtagag
      121 gatctacaat gactgatttt aaatttttta aggcggatag agtttacaac gaattatttt
      181 atcaatttcc aaaagtcttt attgtttctg acgaatacaa aaaaatgaaa gattcaacta
      241 agattgccta tatgctttta aaagcaagat tagagatcgc aatcagcaaa cggcaaatcg
      301 atgaagaagg taatgtttat tttacttata cgacaaatga actatgtaga gtattaaact
      361 gccaaaaaca aaaagcgata gcaatcaaaa aagagttgga atcctttggt ttattattac
      421 aaaagcagat gggatttaac aaacagttag ggaaaaataa tcctaataga ctatatctag
      481 cagaattaaa agtctcagaa aatgatatct acttactcga aaaatttgat agagagaata
      541 gggaaaacgt tgataaatca gagggtatga aaatcatacc caccctcgac gaaaaatcag
      601 acgctgaatc ccttggggct caagagggta tgaaaatcat accgtgccaa aacgttgata
      661 aatcagaggg tatgaaaatc ataccagaac ttaataataa tatattagac actaatagac
      721 acaatataga cactgaaaaa gaccgcctac aagatcaatt gttgttagac aattttgaga
      781 caattatgac aaacgacagc attgctacgt ttgtccctga acgagtatta aatttgataa
      841 aaacattttc ttcaagttac agtgaagctc aaaaaaccgt ccagactatt cataatgcaa
      901 agaaaaaagc tgaaatagaa agtgatattt cgatagtttt tgaagaactc gatagttatt
      961 atgtcaatgc agaacaagaa ttatacacga cactgttaaa agcctatcaa aaattaaaaa
     1021 ccgaaaaagt cgaaaatatc cagaacctga tttttgtcta tgtaaaaaat tggtttatcg
     1081 aaaaaccaat agctgctaaa gtatcaagtg aaaaacgttt gaattatgca agctccccaa
     1141 gcactattac gaaagactgg ttagagtgaa actttactga caaagtgatt gttgcttcat
     1201 ggagtaacat taaaattaaa aattttttat tattcta
//
LOCUS       DAZAOD010000225         1195 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.235, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000225 DAZAOD010000000
VERSION     DAZAOD010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.235"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1076
                     /locus_tag="ACHDPO_002974"
     CDS             <1..1076
                     /locus_tag="ACHDPO_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFN3370517.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DAZAOD010000226         1135 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.236, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000226 DAZAOD010000000
VERSION     DAZAOD010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.236"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..148
                     /locus_tag="ACHDPO_002975"
     CDS             <1..148
                     /locus_tag="ACHDPO_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFN3370518.1"
                     /translation="SKMYMDEHMTLSLDPRLGVFTLESPSGSLDSHVQLVDLRPEKFS
                     GIKQ"
     gene            complement(262..891)
                     /locus_tag="ACHDPO_002976"
     CDS             complement(262..891)
                     /locus_tag="ACHDPO_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFN3370519.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1025..1097)
                     /locus_tag="ACHDPO_002977"
     tRNA            complement(1025..1097)
                     /locus_tag="ACHDPO_002977"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1062..1064),aa:Thr,seq:ggt)
BASE COUNT          378 a          190 c          193 g          374 t
ORIGIN      
        1 ttcaaaaatg tacatggatg aacatatgac cctttcttta gatccacgtc taggtgtatt
       61 tactcttgaa agcccaagtg gttctttaga cagtcatgtt caattagtag atctacgacc
      121 agaaaaattc tctggaataa aacaataact ttctctctat tgtccataaa actagtctca
      181 atcaagctgt attgaaaaaa caagacaaca ttcttaccat ggtaaataaa aagacgacac
      241 attttgtcgt ctttttttaa attaactatt ttcgataaaa gatcgcatag cttgtgccat
      301 tatttctggc ttttctctat tcaattcatg ttttccgttt ttaataaaga gtagccggcc
      361 attcgttgaa agtttatata aacgttttgc tgctggttta ttcgcatgat ctttggtacc
      421 gcataaaatc aatttaggaa gtcgtgatgt acgaagctgt tttttgcagt ctaatgtttc
      481 aagtgaacga agtagggtaa gggtttgttt tttagataga cctaattttt caaatatctt
      541 agaaggtacg cagtaaaaat aaatattctg gaaagtaagc aataagcgat taggagactc
      601 aaattgtgga gcgactaaaa caaccttttt taaatatgga gaaggagttg caagatagtt
      661 taaagcaata acagcgccta aagataatcc acataaaata aaaggttcct ttatctgatt
      721 caattgtact tcgatgtatt tggttaagtc gtctaaagta gcagtgtctg tgctgtttaa
      781 atgattgaac aatgaaagac ttttgcaaga ataactattg ggtagataag agattacatc
      841 tttccatgat tgttcgtctt ggcctagacc atgcaaaaaa acaattttca tattgctctc
      901 ctttttatag ttatcatata gactttcttt gtactattaa aatataaaca ttcatttctt
      961 acgtcataaa ataaaaaaac agcgcagaca cattgttaaa ccaacatgtt gcactgttta
     1021 aggaagccac ttgccgggct tgaaccggcg acctcttcct taccatggaa gcgctctacc
     1081 agctgagcta aagcggcatt atcattaata caaataatag gataacgaat attaa
//
LOCUS       DAZAOD010000227         1128 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.237, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000227 DAZAOD010000000
VERSION     DAZAOD010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.237"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..733
                     /locus_tag="ACHDPO_002978"
     CDS             <1..733
                     /locus_tag="ACHDPO_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFN3370520.1"
                     /translation="ICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            735..>1128
                     /locus_tag="ACHDPO_002979"
     CDS             735..>1128
                     /locus_tag="ACHDPO_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370521.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKS"
BASE COUNT          381 a          131 c          191 g          425 t
ORIGIN      
        1 aatttgttct tttttagtat tatttctttt gttgtttgcc aattcaaaat ttagaaagag
       61 cattagagaa gtactacctg taaaaatcaa atggatggta agcatattat tagttctatt
      121 ggtatatttt tcttttggta ctaattatgc taaggatttt ttagcaacaa ttcctgtatc
      181 gattgataga aaagtagaag ttatagagtc aaatgaatca gataaaactc cacttccaga
      241 aaaagaagta atattacagc attctagtga taactccgaa atttcagctg gtcgttttac
      301 gatttggaaa gctgcgctta aagttataag accaactttg ttatttggtt atggagagac
      361 cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa gtagatcttg atactacaga
      421 tgtgaatgaa ctaaaaagag cacatggaaa catgcataat ggatttcttc aagtacttgt
      481 atcaagtggt ataattgctt ttatatgtat ctatgctttc tatgtgttaa atatctttag
      541 tttactcaaa acatttttta gaagtaaagt gaattatgcg tttcttggta ttgttttaat
      601 ttttatacta tctattttta tagatgaaat ggtggaggct catgtacttt tcaataagcg
      661 cgatgtcatt tcaattgttt tctggtatta tttgggaagc atttcttact tgtatttaaa
      721 aaaggagaat taatatgaag acagctttca ttgcttggac tcctttacat ttgattaata
      781 tattaaatgt ttatcaaaat ttttaccgag aatcaaaagg agatttattt atttattctg
      841 aatttgaaaa cgctagaaga tatagtgagc gtataaaaga attagggcta tttaatgatg
      901 ttgtttttgt gaatcaccgg aaaatcggtt cttcctttaa acgtaaaatt aacttgttaa
      961 ctaaccataa tcaatttttc tcggatgatt tatccgttta tgatgaaatt tttatacagg
     1021 gggaaaatta tttcacaaaa atacttttct ccaatgttta caaaaaaaat ccagatgtaa
     1081 aactaaatta tatagaagat ggtttgggta cttatttgaa gaagagta
//
LOCUS       DAZAOD010000228         1113 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.238, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000228 DAZAOD010000000
VERSION     DAZAOD010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.238"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..482)
                     /locus_tag="ACHDPO_002980"
     CDS             complement(<1..482)
                     /locus_tag="ACHDPO_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFN3370522.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     L"
     gene            complement(472..>1113)
                     /locus_tag="ACHDPO_002981"
     CDS             complement(472..>1113)
                     /locus_tag="ACHDPO_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFN3370523.1"
                     /translation="KNTMINTWNNIKDSFWNIVTGIVNSAENAWTNLKNGVSNAINRV
                     KEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTIKGIAGNIKNWIKGALDIHSP
                     SRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTPSVQPVVNGISHLPITQTKQN
                     ISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQMKRDAGAVGGTLYAT"
BASE COUNT          341 a          206 c          139 g          427 t
ORIGIN      
        1 agcggttttg aagaatactt ctctgggtta taaatttcaa aagtttctgt ttgtcgaata
       61 gtaaatctac cattgtaatt ttccttaaat ggtcgaatac tcactgtaaa ttcaaaaggg
      121 acaatatttc ctgtttttct tgttccttta aattcaggtc cttctattac tacagcttga
      181 taaatatatt gttcatcata gtaaagaata aaatcactat aagacgacat atctaaccat
      241 tcagtgattc gatcttccca ctcctgcacc atatcaattg aaggtgcttt atagtaacac
      301 tcaatctttc tagtcacatt tttgtaatag cctttatcaa taatgataga atcatttcct
      361 tctcgctctc tcaattcaat tactcgacta gctgaaacag aagcaggcct gttttgaata
      421 tacacattaa attcagaaga ataatgttga ttaataaaaa attgtcctct cttaagttgc
      481 atataatgtt cctcctactg caccagcatc tcgtttcatt tgtcttgtca attctgtttt
      541 aatttttgta gtaatctttc gaaccattga atcaggtaaa tctccataaa catttaaatg
      601 taaatgaatt tcttttgttt cactagcaga tatattttgc tttgtttgtg taattggtag
      661 gtgacttatt ccatttacta caggttgaac agacggtgtt tttactaaat ttgtcatggt
      721 ttgatctaac ttactttgct ctttatcaat accaacgata ataccttgaa caatattttt
      781 accaaccata tcacgcatcc atcttgatgg agaatgaata tctaaagctc ctttaatcca
      841 atttttgata ttacctgcaa tacctttgat agtatctttc aaagcattcc acttttcttt
      901 tacaccattt ataagtccat caatgatgtt cttgccaatt tcaaataaat tgacttccct
      961 taacgaatta aagatttctt ttacccgatt aatagcattt gaaacaccat tttttagatt
     1021 tgtccatgca ttttcagcag aattaacaat tccagtaaca atattccaga aagagtcctt
     1081 aatgttattc catgtattaa tcatggtatt ttt
//
LOCUS       DAZAOD010000229         1064 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.239, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000229 DAZAOD010000000
VERSION     DAZAOD010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.239"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..>1064)
                     /locus_tag="ACHDPO_002982"
     CDS             complement(38..>1064)
                     /locus_tag="ACHDPO_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFN3370524.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          178 c          160 g          380 t
ORIGIN      
        1 tttagaaaaa gcagtcggac tttctaaaag aagttcacta ttcgatcctg tcgatgattt
       61 cttcaggaaa atcgtctatt tgcttgtcaa ttttgctgtc tttgtatttc tcttcttgga
      121 tagtcaacaa aatctttgta agattccccc agtctactgc tcttggcgga tcgagccaaa
      181 ccactacttg agatgcactt tcttcatata gattattcct attcgtgatt ataacatccg
      241 ggaactcagg ctttcctgcc tctatcactt ccgtgttcag attaatgtac aagcttaaat
      301 ttttcttgat aaattgatta taggcagcac cataagaaaa atcgatgatg atctttactg
      361 gttcagaaat cagttgaatg ggtatgtgat tgatcaataa taataaataa ctgaaaaaaa
      421 gaaaaaattt atcttgaagc aactctttgc gttttgacgt tagatcattt atatactcta
      481 tcaaatagca ataaaatgct ggatagtttt ctctaaaaaa agaaacatca agtggaaatt
      541 catcagcttt attaatagtg taatgcaaaa gtttaaaatg tattttggtt aactctcttc
      601 ggatcaattg gctcgtctct tctcgcaaca gattaaactg attttcaaaa ctttcaatga
      661 atcgttcatt caaccattcg attgtttcat cttcattttt tctcaagtat ttttgatcca
      721 atttatcatg aagataaagc caagagagtg tcttattgat aaaaataacg gatttttctc
      781 ctaatactcc ttttaagtgg taaaatccta tatccgaaaa aaatagcgac tgattgctag
      841 caatatctaa agaatcagct tgttcagcca acaggttgat tgctaaaaag tggaataatt
      901 tctttttttc ataagcagac agaggataat actgttttaa atcttttaac attttttctg
      961 tttttataat tataggtagc gtatacaatt ccacaaaact tatctctgtt gagttaaaaa
     1021 gattatataa aaaaagccga atgtttttag gattccctgt caac
//
LOCUS       DAZAOD010000230         1059 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.240, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000230 DAZAOD010000000
VERSION     DAZAOD010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.240"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..254
                     /locus_tag="ACHDPO_002983"
     CDS             <1..254
                     /locus_tag="ACHDPO_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFN3370525.1"
                     /translation="GCPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWN
                     HLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
     gene            complement(238..831)
                     /locus_tag="ACHDPO_002984"
     CDS             complement(238..831)
                     /locus_tag="ACHDPO_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFN3370526.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
BASE COUNT          313 a          215 c          188 g          343 t
ORIGIN      
        1 aaggctgtcc ttttgataat gccgtagctg aatcaactta taagtcgttg aaagtagaat
       61 ttgtctatca atacacattt gaaaccttac aacaattgga tttggagtta tttgactatg
      121 taaattggtg gaaccacctt cggttgcacg gtacacttgg ctacgagaca ccggttggtt
      181 accgtaacca gagattggcg cagcgaatcc ttgataatga gctcggatgt gctaacgcta
      241 gcgaggcagt ctaactttaa ctgttagctc ctgccgaaga tcgtcacatc cgaggaggct
      301 cattgtcaag gacaatcgga atagcatacg gaaagaagtt ctgcacctta taaaatttgt
      361 caaaaaaact gttgccattc caccagacac ttgcttaaag cgaaaaattt cttcaatgtc
      421 catgcctaat tctttggata ttctcttgtc tgaccatcca ttttttacta atctttggat
      481 gacaatttcc attcctctta tttcatgggt ccctcttgca cgattgtgtc gaattgttga
      541 agccatacgt tcttctatgg gtttatcaat aactgttacc ggtacaactt ttaagttgag
      601 tctttcctta gcaacacgat acctatgaag cacatcaacc aagatatact tctcttcttt
      661 ttccttgtaa taacaaacta atggttgagt aaagccatct tcaatgatag aaagctccaa
      721 taagttcatt tccggagacg ctactcgatt gggattataa tcgttcgcct gtattttggt
      781 aattggaaca agccgaacgt ccatcacagg gaaagttatg tctttattca tacgcttgta
      841 taccctactt tcttaaaaag tagggtatac tcaagaatcc gattaattat cttctcaatt
      901 tggataatat atctcatcag tcttcttgtc actttatcaa catgattttg ctgcaaaatg
      961 ggataccgac agtactggac tggtaatcag gataaaagca aaaataatta atttgtatcc
     1021 taaaaaatcc ataaaaattc tctcacattt tcgggtatt
//
LOCUS       DAZAOD010000231         1035 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.241, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000231 DAZAOD010000000
VERSION     DAZAOD010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.241"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>1035)
                     /locus_tag="ACHDPO_002985"
     rRNA            complement(<1..>1035)
                     /locus_tag="ACHDPO_002985"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAZAOD010000232         1021 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.242, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000232 DAZAOD010000000
VERSION     DAZAOD010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.242"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..460
                     /locus_tag="ACHDPO_002986"
     CDS             2..460
                     /locus_tag="ACHDPO_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFN3370527.1"
                     /translation="MLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            469..696
                     /locus_tag="ACHDPO_002987"
     CDS             469..696
                     /locus_tag="ACHDPO_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370528.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          319 a          166 c          180 g          356 t
ORIGIN      
        1 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
       61 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
      121 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
      181 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
      241 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
      301 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
      361 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
      421 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
      481 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
      541 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
      601 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
      661 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
      721 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
      781 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
      841 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
      901 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
      961 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1021 t
//
LOCUS       DAZAOD010000233         1002 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.243, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000233 DAZAOD010000000
VERSION     DAZAOD010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.243"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            369..1002
                     /locus_tag="ACHDPO_002988"
                     /pseudo
     CDS             369..1002
                     /locus_tag="ACHDPO_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          183 g          295 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac ct
//
LOCUS       DAZAOD010000234          983 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.244, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000234 DAZAOD010000000
VERSION     DAZAOD010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.244"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>983
                     /locus_tag="ACHDPO_002989"
     CDS             <1..>983
                     /locus_tag="ACHDPO_002989"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFN3370529.1"
                     /translation="EPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITDS
                     EYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQLD
                     DTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTGK
                     KNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVGS
                     IAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFYE
                     NFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKM"
BASE COUNT          374 a          159 c          189 g          261 t
ORIGIN      
        1 gaaccaggcg attttatcat gagtggcgct ggaacaattg ggagaatttc aagagtacca
       61 aagcaaataa aaccgggtgt attcaatcag gctttgatta gacttagaat aaataaagaa
      121 atcacagatt cagaatattt tattcaattt attcgtgcag attttatgca aagaaaactc
      181 acaggagcta atccaggttc agcaattaca aatctcgtac caatgtcaga agtgaaaaaa
      241 tggatagtac aatttccaat attagaagaa caaaagaaaa ttgggaactt cttcaaacaa
      301 ctggacgaca ctatcgctct tcaacaacgt aagctagatt tattaaagga aacgaaaaaa
      361 ggattcttac aaaaaatgtt ccctaaaaac ggagcaaaag tgccagaaat tcggtttcct
      421 ggatttacgg aagattggga acagcgtaag ttcaaagagt ttagtaagaa gactggaaaa
      481 aagaacacga aagatttaga cttccctgcc tattcggtaa gtaataaagc aggtttaatt
      541 tctcaaacag aacagtttga tggtagtagg ttggatgatt tagaaaaaac aaattataaa
      601 ttcgttgaac caaatgaatt cgcctataat ccagcaagag taaacgtagg atcaattgca
      661 tttaacaatc ttggtatgac ggtcattgtt agctctcttt atgtagttgt gaaaatgagc
      721 gaggacttag ataatgagtt catacttcag tttatcaagt caccaacatt tatcaaagag
      781 gtcaagcgca acactgaagg aagcgtacga gaatacttat tctatgagaa tttcgctaat
      841 atcaagtttc cttttactag gaataaagag gaacaacaaa aaatcggcgc tttcttcaaa
      901 caactcgacg acacgatcgc tcttcatcaa cgtaagttag atttgctgaa ggaaacgaaa
      961 aaaggcttct tacaaaagat gtt
//
LOCUS       DAZAOD010000235          965 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.245, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000235 DAZAOD010000000
VERSION     DAZAOD010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.245"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(53..787)
                     /locus_tag="ACHDPO_002990"
     CDS             complement(53..787)
                     /locus_tag="ACHDPO_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFN3370530.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
BASE COUNT          334 a          197 c          181 g          253 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagt
//
LOCUS       DAZAOD010000236          935 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.246, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000236 DAZAOD010000000
VERSION     DAZAOD010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.246"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            57..749
                     /locus_tag="ACHDPO_002991"
     CDS             57..749
                     /locus_tag="ACHDPO_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFN3370531.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          412 a          143 c          158 g          222 t
ORIGIN      
        1 tgtttgagat cacttacttt tagcatgtaa aagtattgga ttaaggagct atgcaaatga
       61 aaaagaaatt tattactggt gggattgtcg ttgcatttct atgtctaatt ggctacacag
      121 gcacgcggta cgcaaatgaa attattttgt ggggtggaga gacagatatt gatacaatca
      181 atgagaatct gacacagctt gatcatacat tgacagataa agagcaagcg attacagatc
      241 ttaccgctcg actagcacaa aaagaacaga cattgcaaga ttcaaaggca gatgtccaag
      301 aataccaaac aaaagtaaat gaattagaaa accaaaaaaa tcaatcggca gcagaaaaac
      361 aaaacttaga aagtcaatta gtcagcaagg atgcacaact acaaagcaaa caaaatgaaa
      421 tcaatgtcaa actagatgag atcaaccaaa aaaatgatga aatcaatcat ctgaatgcag
      481 attggacagc aagactacaa gaagcacaag caaaactttc agaattacaa aatactgtaa
      541 atggtttgaa tcaacaaatc gcaacactga cacaagaaaa aacaaatgta gaaactcagt
      601 taacagatac acaaaagaaa ttagacgaag caactgctga aaactcaagc tggaaacaat
      661 atattcaaaa gttagaaaaa gcaaaagatg aagtggaaga tacagctgat aaatctcagc
      721 aaattgttga agaacatttg cgtaaataat ctttcttaac aagtaaacct aaattagtaa
      781 agaagcaaca gtaatctata ctaagtagtt cagttttgga gtacaaaatg acaaaatgta
      841 cttcaaaatg gactactttt ttcattttaa cttacatacc aaattacata caaaatgatt
      901 tataaaatgc aattgaaaat gataattgaa tgaaa
//
LOCUS       DAZAOD010000237          884 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.247, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000237 DAZAOD010000000
VERSION     DAZAOD010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.247"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(127..675)
                     /gene="aac(6')"
                     /locus_tag="ACHDPO_002992"
     CDS             complement(127..675)
                     /gene="aac(6')"
                     /locus_tag="ACHDPO_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFN3370532.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          251 a          188 c          135 g          310 t
ORIGIN      
        1 gtacacggtg ttccaaaagt agcttcttcg gaaataagtt ggaatttcac aaaaattcaa
       61 gaagtaattt tcgtaaattc cttcttattt cttgaagctg attacttctg tcacaacctc
      121 tttttattat tgagaatttg gtcgaggaat aatcgttttt gccatccaaa tatccggttt
      181 gtcccagcca tttgcatttg gtaagacacc tacgatttta taacctaatt tttcatagaa
      241 ttcatacgga tgttcacgaa ggttctggat ggaagccact ttatcaaatg tatgctcata
      301 caggtccgtt tgacttaacg ttgttccatg gtctaaatca tccgtaccta aataaatcgt
      361 gattcctcct ctggaagcta cttctttttc taagtaattg actaatcgag tacctatttg
      421 gttctttcgt cgggagcttt ctacaactaa tggatgcaat tcccaacctg tgataccgta
      481 ttgagggatt gcaccaataa atcctactaa ctcatcttgg tctaccgctg ctaccgcgat
      541 tcgttctgga ttcatcattt cttctacttc ttctgccgag ctgtctccat attcttccgg
      601 ccaagtcagt ctcagtaaat cagaaagctg atctttcaat actggattat tacggtcaaa
      661 ttcactgatt atcatacgtc ttcccccttg ttcttgctta ttctaacagt ccttttgaaa
      721 aaacgaaatg ttctcgctca aaaatcttta gctaccaatc agtatctcta ttctttcatt
      781 atttatctta cttataaaat aaaaaattat acagaaacac tttattcaaa ataggaaaga
      841 tcaggaaagc catcaattgg aggaaaaaac tctgtttgtt catc
//
LOCUS       DAZAOD010000238          872 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.248, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000238 DAZAOD010000000
VERSION     DAZAOD010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.248"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>872
                     /locus_tag="ACHDPO_002993"
     CDS             <1..>872
                     /locus_tag="ACHDPO_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFN3370533.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYV"
BASE COUNT          295 a          149 c          178 g          250 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gt
//
LOCUS       DAZAOD010000239          871 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.249, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000239 DAZAOD010000000
VERSION     DAZAOD010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.249"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>871
                     /locus_tag="ACHDPO_002994"
     CDS             <1..>871
                     /locus_tag="ACHDPO_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFN3370534.1"
                     /translation="VALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFD
                     KKQWRYALKISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIW
                     MSTNNAWVPWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYY
                     SGLSLVVPITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLG
                     IIAAGYTTVFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQM
                     LIRYVLTSLLIISL"
BASE COUNT          282 a          107 c          147 g          335 t
ORIGIN      
        1 gtagctttga tgcagacatt atattttgat gataaatatg ttggcagagt agtcggcgga
       61 acactgtcat ttgtgttgat aggtttagta atttatttaa gaataatgat aaagggtgct
      121 catttttttg ataaaaaaca gtggagatac gctttaaaaa tctctttgcc gctaatccca
      181 cattccttag caaatatagt tttagcacaa ttcgatagaa ttatgattaa ttcttattta
      241 ggtcctgctg cggggggaat atattcctac attagtaaca taggtattat tctaagcgta
      301 atatggatgt ctactaataa cgcctgggtt ccatggttct atggtgagat gagtaaaaat
      361 aatgaaaaaa aagtgaagaa agttagtaac tattatttag tagtctttac tttgattacg
      421 atgattgtaa tggtagtttc gattgattta gcaaaattta tggctccgaa agactattat
      481 tctgggttat ctttagtggt tccgataacc ttaggctatt tctttcagtt tttatatagt
      541 ttaccagtta atgctgaatt ttatgagaaa aaaacatcgt ttattgcgat tggtacagta
      601 gcaagtgcta tagttaatat actattaaac atgattttca tacctaggtt aggaataatt
      661 gctgctggat acacaaccgt atttacgtat tttttacttt ttatttttca ttataatatc
      721 gctaaaaaaa ttacgaataa acaattattt gacacaaaaa aaatatgtat cataataatt
      781 tttgtatcaa ttttttcttt gatacttcat attttaatca atcaaatgtt gattcgttac
      841 gttttgacat cattattgat aattagttta g
//
LOCUS       DAZAOD010000240          813 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.251, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000240 DAZAOD010000000
VERSION     DAZAOD010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.251"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(347..460)
                     /locus_tag="ACHDPO_002995"
                     /pseudo
     CDS             complement(347..460)
                     /locus_tag="ACHDPO_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          290 a          128 c          130 g          265 t
ORIGIN      
        1 ccatctggaa tttgtctttt tcgttgcttt gctcataaaa atctgcatat tcatcactaa
       61 tattttttct aataaattct tccatcataa agatcacctc gaaaagagta tacgaacaaa
      121 cgttcttttt gtaaaggtgg aatttattat actaaataaa taggtgaaca agtacttgtg
      181 ccaaattatg tgccaaaaaa aatcgaattt aataaaacac aaacaaaaag aaatcctatt
      241 atgataacat ttcttataat aacaaacaca acagaagacg tgtaatagtt agtcaggaac
      301 gtacaaataa cccctgtatc ctttgcggta cagggggtta ttttgtataa gtagacattg
      361 tagtttctaa actgctatgt cctaaacgtt tcgatacgct aagtatattt actccttgat
      421 aaagtaaaat agatgcatgc gtatgtctta gtccatcaat aaacagtcga agagaaaata
      481 gggaaaaatt gattactaaa gaaaaactta ctaggtcgac ggtgtagttg attttcatac
      541 ttcaatagat tcgaattaaa cgatttcgat tggcttatac cagtcctatc caacgaaaga
      601 tatatcgttc ttaactctag cggtataact tgaagcttta cgtaaagcca atgggaatga
      661 actggagatg actttttatt atttttagta atagctgatg ggttaatact tacaactttc
      721 cttttcaaag taccatataa aaaaacggtg gggttgttta gcgaaataaa ggatctaagc
      781 caatagctta gatcctttat tctatgcttt ata
//
LOCUS       DAZAOD010000241          696 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.254, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000241 DAZAOD010000000
VERSION     DAZAOD010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.254"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(54..629)
                     /locus_tag="ACHDPO_002996"
     CDS             complement(54..629)
                     /locus_tag="ACHDPO_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFN3370535.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          230 a          151 c          124 g          191 t
ORIGIN      
        1 aatgaaaaaa cagagccaga ttagcattat tttgctaatc cagctctgtt tattcagcct
       61 atttttcttt ttgaatatat caagcgttgg ggcaacatag tgatgactaa tgaaacaacg
      121 acgatagaca acaagcgatc aaggtagtct gtacccgcct gtaccaagat cacacttgtt
      181 gtctgactta aacctaaccc atgtaatagc tgaacgatca tactggatcc tgaggaggtg
      241 atcccgccaa ataactgaac ggtaatgatc gaagaaacga tcgttccagg taccgacaaa
      301 atcaaagcga gtaataacag tttcaagctg tttttatctt tgccgagata tcttggcaaa
      361 atcaatccag caagcaagcc tgtgagaatt tggattggcg aataatacag agaaaaaata
      421 tctgtagtca ctccacttaa aataccgctg gacaatcctg tcagcattcc aggtacaggc
      481 ccaagcaatg caccagcaaa aatcgttccg atagaatcga gatagattgg caaacgaagc
      541 cataaagcaa tcgttcctcc aatataattg atcccaatac acaaagccat cactgtaagt
      601 acgcgagttg ccattttgtt tttattcatt ttgttagccc atctttaacc tttccaaatc
      661 tttcataatc gtttcttctt gtgcatttaa aagaac
//
LOCUS       DAZAOD010000242          645 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.257, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000242 DAZAOD010000000
VERSION     DAZAOD010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.257"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..227
                     /locus_tag="ACHDPO_002997"
     CDS             <1..227
                     /locus_tag="ACHDPO_002997"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370536.1"
                     /translation="LKSFRINLPNKFIGGFKMSHTLLIKDTLNILDLNINIHFEENCL
                     TKEKYKGQICLIYKGTLQYTPEEYPHLPIY"
     gene            287..520
                     /locus_tag="ACHDPO_002998"
                     /pseudo
     CDS             287..520
                     /locus_tag="ACHDPO_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(568..645)
                     /locus_tag="ACHDPO_002999"
                     /pseudo
     CDS             complement(568..645)
                     /locus_tag="ACHDPO_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
BASE COUNT          245 a          126 c           97 g          177 t
ORIGIN      
        1 ccctgaaatc ctttagaatt aatttgccca acaaattcat aggaggattc aagatgtctc
       61 atactctgct tatcaaagat accctaaata ttctagacct aaatatcaat atccatttcg
      121 aggaaaattg tttaactaaa gaaaaataca aaggacaaat ttgcttgatt tacaaaggga
      181 ctcttcagta cacaccagaa gaatatccac atcttccaat atattaaaag aaccttcttg
      241 aatcattgag tgaaagaaaa gagattcgtc actatttgag gactgtttaa ctagagacat
      301 tagcgatctg cctgaaacct atacaaccac tttacgaacg tttaaaaatt ttctgccaca
      361 gattcaaaat gcgcttaact gcagctattc aaacagacca ttggaatgtt taaacaacca
      421 catcaaagta ttaaaacgca atacgtatgg ctttcgcagc ttttacaatt tcaaactacg
      481 gatcatgatt cgtcatggca aaacattttt aaccaaataa acagaagaat gtgggataaa
      541 tctaaaaatc agttttgcta cagactctcg agtaaacggc gggagcagaa gcaactcctt
      601 cggaaataag ccgaaattca caaaaatttg aaaagcaatt ttcgt
//
LOCUS       DAZAOD010000243          644 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.258, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000243 DAZAOD010000000
VERSION     DAZAOD010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.258"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..635)
                     /locus_tag="ACHDPO_003000"
     CDS             complement(39..635)
                     /locus_tag="ACHDPO_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFN3370537.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          242 a          124 c          104 g          174 t
ORIGIN      
        1 aacattgtca atcaatgact aattttacaa aataaatatt atccaagaag accacttaga
       61 tattgacctc cataaatcaa ggccatacta tataagaaaa tcgacagtgg tttagcaatc
      121 aaaatgatta gtgtatatcg tttcactgac atgtttgtca atccagccat caaacataac
      181 gcatcgtcag gagcaactgg aagaaaaata gctagagcaa acagcttctc aaaacggttt
      241 tgattatcca gccagccaat atatttgtta tatgtcttat cgctaatcat ggaaagtatg
      301 aatggctttc cataacgacg ccctagcaga aaaatgataa tcgaaccaat gcagattcca
      361 atatagttat agataaatcc agcataaggg ccaaatatca ggacaccagc tgcagtactg
      421 atccctccag gaatgattgg aataactact tgcaggattt ggatgaagac aaaaataatc
      481 ggtcctaaaa tgatggaatc acctactaat cctcttaacg cattcaaatc tttgaaaaca
      541 cctaaattaa taaaataaat cgtcagcgcg attgataggc ctaatccgat aatggatatg
      601 aaatttatca gttttcgaga ggcagcaata ttcattattc atca
//
LOCUS       DAZAOD010000244          597 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.259, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000244 DAZAOD010000000
VERSION     DAZAOD010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.259"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>597
                     /locus_tag="ACHDPO_003001"
     CDS             <1..>597
                     /locus_tag="ACHDPO_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370538.1"
                     /translation="LHVCKTTLLNDINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRC
                     KIMQQLSQNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIE
                     IDRYSPRFTEMERRLLLLNVSYRLGGFNSWELPESFFERADRFIESVTENSGRFYDKE
                     NKEILSIGFAISFLRQQVCAVTIDSKFIEEIKKRPIYNY"
BASE COUNT          196 a          105 c          103 g          193 t
ORIGIN      
        1 ctgcatgttt gcaaaaccac tttactcaat gatatcaata acataaaaaa agaatttgaa
       61 gaacagatcg cttatacaca tcgggaaaag gaccgttaca ctttatattt ttcagaacat
      121 atacctcgat gcaagatcat gcagcaattg tctcaaaatt cgttgttttt aaaaacttgt
      181 ctgctttatt tggaagaaga tgaacctgat tatcttcaat taactgaatg tgaattcatc
      241 tctgtcagca aagcttattc attaaaaaaa caagtattag cttattttaa tgactgcggg
      301 atcgaaatcg accgctactc ccctcgattc actgaaatgg aaagacgtct gctgcttctt
      361 aatgtgtcgt atcgtttagg cggttttaat tcttgggagc tacctgaatc gttttttgaa
      421 cgtgccgatc gtttcattga atccgtaacg gaaaatagtg gcagatttta tgataaagaa
      481 aataaagaaa tcttatcgat tggttttgct atcagtttcc tacgccagca agtgtgtgct
      541 gtgacaatag attcaaaatt tatcgaagaa atcaaaaaac gtcctattta caattat
//
LOCUS       DAZAOD010000245          588 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.261, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000245 DAZAOD010000000
VERSION     DAZAOD010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.261"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(65..150)
                     /locus_tag="ACHDPO_003002"
     tRNA            complement(65..150)
                     /locus_tag="ACHDPO_003002"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Leu,seq:taa)
     gene            complement(167..238)
                     /locus_tag="ACHDPO_003003"
     tRNA            complement(167..238)
                     /locus_tag="ACHDPO_003003"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Gly,seq:gcc)
     gene            complement(250..322)
                     /locus_tag="ACHDPO_003004"
     tRNA            complement(250..322)
                     /locus_tag="ACHDPO_003004"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Thr,seq:tgt)
     gene            complement(340..421)
                     /locus_tag="ACHDPO_003005"
     tRNA            complement(340..421)
                     /locus_tag="ACHDPO_003005"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(385..387),aa:Leu,seq:tag)
     gene            complement(429..501)
                     /locus_tag="ACHDPO_003006"
     tRNA            complement(429..501)
                     /locus_tag="ACHDPO_003006"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(466..468),aa:Lys,seq:ttt)
     gene            complement(505..577)
                     /locus_tag="ACHDPO_003007"
     tRNA            complement(505..577)
                     /locus_tag="ACHDPO_003007"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(542..544),aa:Val,seq:tac)
BASE COUNT          149 a          169 c          138 g          132 t
ORIGIN      
        1 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattt
       61 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
      121 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      181 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      241 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      301 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      361 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      421 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      481 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      541 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAZAOD010000246          553 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.262, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000246 DAZAOD010000000
VERSION     DAZAOD010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.262"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          166 a          126 c           73 g          188 t
ORIGIN      
        1 gatgccgttt tttttagaga aatttaaaaa agaccgtacg aatctcgcat tatccgatta
       61 cttttccaga aaagatcccc aattctgtat aaataaccct atcttcttgt tggtttcatt
      121 ttctcatata agaattcagt caatctaccc actatgacca ttactacgtc caacacaact
      181 gacatattaa ccacgtaagt attccctcac agatctccga atctccatgg tatggattcc
      241 catcctgacg ctgcagagga caacatattt catgtggctc tgtacccttt tgatttggaa
      301 acactacaaa tcaatactca tctataactt atcaagcgaa ctttcgctag gcttctagtg
      361 attactaaat tgttggataa catacatagc ccattttatc tagctgttat tcataacagt
      421 tagttcttgt attacttctt ccgcttgtgt tgccattgag cttgtcaaaa agttacttag
      481 aaaaaagctg ccagtaaagc aactttcaac aaaccctttt tgtttcttat catatcaaga
      541 aacctccttt tat
//
LOCUS       DAZAOD010000247          552 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.263, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000247 DAZAOD010000000
VERSION     DAZAOD010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.263"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(132..509)
                     /locus_tag="ACHDPO_003008"
     CDS             complement(132..509)
                     /locus_tag="ACHDPO_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370539.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
BASE COUNT          165 a           99 c          100 g          188 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aa
//
LOCUS       DAZAOD010000248          536 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.265, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000248 DAZAOD010000000
VERSION     DAZAOD010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.265"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            112..306
                     /locus_tag="ACHDPO_003009"
     CDS             112..306
                     /locus_tag="ACHDPO_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370540.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          227 a           68 c           87 g          154 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtt
//
LOCUS       DAZAOD010000249          535 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.266, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000249 DAZAOD010000000
VERSION     DAZAOD010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.266"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>535
                     /locus_tag="ACHDPO_003010"
     CDS             <1..>535
                     /locus_tag="ACHDPO_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HFN3370541.1"
                     /translation="RTNDSLETTIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMS
                     KIVSEDVSAFKERTLEAKYSVIFMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGF
                     TIAPTESAYVWKEILQDLKDRGLEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHIS
                     RNIAHKVRVSDRQEICS"
BASE COUNT          187 a           80 c           98 g          170 t
ORIGIN      
        1 aaagaaccaa tgactcttta gaaaccacta ttattcagct agttcaaaaa ggaattacta
       61 tgtccgaaat ctctgatcta atcgaaaaaa tgtatggtca ttattacaaa ccacaaacta
      121 tttcaaatat gagtaaaatt gtgtctgaag atgtttcggc atttaaagaa agaactttag
      181 aagctaaata ctcagtcatt tttatggatg ctactcatat tcccttaaaa agacaaaccg
      241 tatcaaaaga agctgtctat atagtaattg gtatcaggtt ggatggaact aaagaggttc
      301 taggatttac tatagctcca actgaatctg cttatgtttg gaaagagatt cttcaagatc
      361 taaaagaccg tggtttagaa gaggttttgt tagtcgtaac agatggttta agtggtattg
      421 acgatagtat tcatagtgtt tatccaaatg ctcaatttca acaatgttgt gtccatatat
      481 ctagaaatat cgctcataag gttcgtgtta gtgatcgaca agaaatctgt agcga
//
LOCUS       DAZAOD010000250          534 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.267, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000250 DAZAOD010000000
VERSION     DAZAOD010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.267"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>534
                     /locus_tag="ACHDPO_003011"
     CDS             <1..>534
                     /locus_tag="ACHDPO_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HFN3370542.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DAZAOD010000251          516 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.269, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000251 DAZAOD010000000
VERSION     DAZAOD010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.269"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(163..366)
                     /locus_tag="ACHDPO_003012"
                     /pseudo
     CDS             complement(163..366)
                     /locus_tag="ACHDPO_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            332..>516
                     /locus_tag="ACHDPO_003013"
     CDS             332..>516
                     /locus_tag="ACHDPO_003013"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370543.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQP"
BASE COUNT          163 a           78 c           80 g          195 t
ORIGIN      
        1 cctgttttta cagtgaatta ttttaatttt gattttcaat aaaaatatat tacaataata
       61 atcgtaatag ctaatgaaac aatttctcaa tctttttacc actccaaaca gggagcgtca
      121 ataattttgt gtaaataact cgtccttctg caaaataatg ggttactcag taaacattga
      181 agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga atttttgatt
      241 gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt gaaactgctc
      301 ttttctgcgg ctgtatttct tgatttgttt attgaaagat tcgattgtag aaccagaagg
      361 aatggagaac acttttgaac tttacaacaa aactactgtt gataaattaa ttccaatttt
      421 agttccaact gatttaaatg gtcatgatgt tttacttcgt tttaacggat ttttaggtga
      481 ggattataga tacctaaaaa tttctgatcc tcaacc
//
LOCUS       DAZAOD010000252          468 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.272, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000252 DAZAOD010000000
VERSION     DAZAOD010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.272"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>468
                     /locus_tag="ACHDPO_003014"
     CDS             <1..>468
                     /locus_tag="ACHDPO_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFN3370544.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAZAOD010000253          451 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.273, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000253 DAZAOD010000000
VERSION     DAZAOD010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.273"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>451
                     /locus_tag="ACHDPO_003015"
     CDS             <1..>451
                     /locus_tag="ACHDPO_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFN3370545.1"
                     /translation="FRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVR
                     TLNDKYVAIFMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNE
                     LLQDIYSRGVHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRN"
BASE COUNT          147 a           89 c           87 g          128 t
ORIGIN      
        1 tcttccgaaa aggtattacc atgtcggaaa tcgcagactt gattgagaaa atgtatgggc
       61 atcactacac gccccaaacc atgtccaaca tgactaaagt gctgactgaa gaagtaaatg
      121 catttaaagt tagaactcta aatgataagt atgtcgctat tttcatggat gctacttata
      181 ttccattaaa acggcaaacc gtctccaaag aagcaatcta tattgccatt ggtatacgag
      241 aagacggcac taaagaagta ctaagttatg cgattgctcc gactgaatcg acctacgttt
      301 ggaatgagtt gttacaggac atttactcca gaggggttca tgatgtctta ctgtttatta
      361 ccgatggctt aaaaggcatg aaagatacga ttcaccagat ttatcctaaa gctaaatacc
      421 aacattgctg tgttcacgtt tcccgtaata t
//
LOCUS       DAZAOD010000254          443 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.274, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000254 DAZAOD010000000
VERSION     DAZAOD010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.274"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>443
                     /locus_tag="ACHDPO_003016"
     CDS             <1..>443
                     /locus_tag="ACHDPO_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFN3370546.1"
                     /translation="GTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADD
                     TEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKV
                     DVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          179 a           67 c          103 g           94 t
ORIGIN      
        1 ggaacaacag tctttgcagt gaaagacggc gtaagcttac cagaagataa acttccagtg
       61 ttgaaagcaa aagatggtta tacagatgcg aaatggccag aggaagcaac tcaaccaatt
      121 acagcagatg atacagaatt tgtatcaagt gcaacaaaac tggatgataa atctgacgct
      181 gacaaatata atcctgaagg tcaaaaagtg actacagaat tgaataagga accagacgca
      241 tttgagggaa ttaagaacaa agaagattta ccaaaagata ctaagtatac ttggaaagaa
      301 aaagtagatg ttagcgcagc tggaaataaa aaagggactg ttgtagtgac atatccagat
      361 ggatcatctg atgaagttga agtagatgtt acagtgacag acaatcgttc tgacgccgat
      421 aaatatgagc caacagtaga agg
//
LOCUS       DAZAOD010000255          432 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.276, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000255 DAZAOD010000000
VERSION     DAZAOD010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.276"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..368
                     /locus_tag="ACHDPO_003017"
     CDS             3..368
                     /locus_tag="ACHDPO_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370547.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
BASE COUNT          111 a           86 c           62 g          173 t
ORIGIN      
        1 agatgataaa aacttgctgg aaaaaccttc cgttgctttt atcttttgtt ccttatgtgc
       61 atttcgcctt actgcttgat tttcgttatc attccgtaag cgggttcatc acattgatat
      121 ttttatctct ttttgctgga tattattttc aaaggaacag gcgtattata tctttattca
      181 ttgccaatat tatatctact gtcacttcct atttattttg cgccaatttt actgaatggc
      241 gttacttcta tcatccttta aaaccgaccc agctgatctt gcttcttgca ggtatttact
      301 tagttccaca aatccttggg tcgttatggg cggtagcctt atcttataaa aaagctcggc
      361 atccataaaa acaaaccata tatgtacaaa gagaagctac tttcttcttt ttatacatat
      421 atgtttttct ta
//
LOCUS       DAZAOD010000256          427 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.278, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000256 DAZAOD010000000
VERSION     DAZAOD010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.278"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            128..>427
                     /locus_tag="ACHDPO_003018"
     CDS             128..>427
                     /locus_tag="ACHDPO_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFN3370548.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
BASE COUNT          156 a           44 c           72 g          155 t
ORIGIN      
        1 tagatttctt ttgcatcaaa taaggtattt aacaattaag tatttaaaag ataactttta
       61 agttatcttt aagtaatgct taaagctatg ttatactcta ttaggaaata taagaaggag
      121 tataaaaatg aacaaacata atagaaaaat aacgaataac aaagaactga tcttgttact
      181 aatagggatt tggggtatct ttttactctt taatatgtat atgccgacta tgagagcgga
      241 tgacgtagtt tatgcaagta gattagatga acttggctat ttgggtgctt cgatagaaca
      301 ttataagaca tggagttcaa gaattattat agaactattc ttaatgttct tttctaaaca
      361 ctttatgcta tggaaattat taaattctac gattatgtta ggaattgtag tattactttg
      421 caagtat
//
LOCUS       DAZAOD010000257          424 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.280, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000257 DAZAOD010000000
VERSION     DAZAOD010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.280"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          130 a           86 c           50 g          158 t
ORIGIN      
        1 aaaaaaacag atgaaagatc aggttttatt agatctcatt ctttcatcac ttgaagggat
       61 ttaatgaact actttttcct ctttgtcgtt tttatatatt cgtattcctt caaacagtag
      121 gatagcctct ttcaatgctt gatatttgaa ctgtccgtta cttaaaaatt tagatgtgcc
      181 gccctcttcc tagaacatat tcttttttac tttttcatta attgacagac caatcgaacg
      241 aaactgtaaa tttcgatagg ataatgattg gtcaaactca ttcattttca agacatctcg
      301 attcatattc aagataggaa tctttttatc aacatcactt tattcgtatt ttcctctacc
      361 ataaaagctt cacgctccac aaaattgttt tatacactac tattcagccc attcaacgac
      421 caat
//
LOCUS       DAZAOD010000258          423 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.281, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000258 DAZAOD010000000
VERSION     DAZAOD010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.281"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>423
                     /locus_tag="ACHDPO_003019"
     CDS             <1..>423
                     /locus_tag="ACHDPO_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFN3370549.1"
                     /translation="MHLSHKYGFTKELILADGFRISGEVQSLFLENNKGNMARSVALE
                     INGFTNIFEQTSPDFVLLLGDRGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHA
                     ITKIASVHFAATEKSKERLIKMGEDSWRVFPVGAPRIDT"
BASE COUNT          141 a           59 c           98 g          125 t
ORIGIN      
        1 atgcatttat cccataaata tggatttact aaagaattga tcttagctga cggatttaga
       61 attagtggag aagttcaaag tttgttttta gagaacaata agggaaacat ggctcggtct
      121 gtggcattag agataaatgg tttcacaaat atatttgaac aaactagccc tgattttgta
      181 ttattactag gggatagagg agaaatgttg gcagctgcga tagcttgttt gtatcttgga
      241 atcaaaacag cacatattca cggaggcgaa gtgtctggta ctgtagatga atcaataaga
      301 catgccataa cgaaaatagc atctgttcat tttgctgcta cggaaaaaag caaagagcgt
      361 ttaataaaaa tgggggaaga ttcttggaga gtttttcccg tcggagctcc tagaatagat
      421 act
//
LOCUS       DAZAOD010000259          384 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.282, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000259 DAZAOD010000000
VERSION     DAZAOD010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.282"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>384)
                     /locus_tag="ACHDPO_003020"
     CDS             complement(<1..>384)
                     /locus_tag="ACHDPO_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFN3370550.1"
                     /translation="KECVNCPLLNQCTISKNHQRVITRHVWGDLMDEVEHLRLTDLNK
                     SIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGK
                     EPLFFCSKIRNEVDKKLFQARVTSL"
BASE COUNT           94 a           88 c           63 g          139 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat gactcgttga tgatttttac ttatggtaca ttggtttagc
      361 agaggacagt tcacacattc tttt
//
LOCUS       DAZAOD010000260          375 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.284, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000260 DAZAOD010000000
VERSION     DAZAOD010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.284"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..132)
                     /locus_tag="ACHDPO_003021"
     CDS             complement(<1..132)
                     /locus_tag="ACHDPO_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFN3370551.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DAZAOD010000261          345 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.286, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000261 DAZAOD010000000
VERSION     DAZAOD010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.286"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>345
                     /locus_tag="ACHDPO_003022"
     CDS             <1..>345
                     /locus_tag="ACHDPO_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFN3370552.1"
                     /translation="AEEFIRSRKAYGSRKIKKALSKRGIQISRRKISRIMKNRGLKSS
                     YTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLF
                     NREILGYSCGEH"
BASE COUNT          129 a           60 c           66 g           90 t
ORIGIN      
        1 cgctgaagaa tttatccgca gccgaaaggc ctacggctca agaaaaataa aaaaagcctt
       61 atcaaaacga ggcattcaga tcagccgacg aaaaattagt agaatcatga aaaatagagg
      121 attaaaatcg agctatactg ttgcttattt taaagtacat cattctactt gcaatgaagc
      181 caaaacgaca aacgtattga atcgtaaatt cttaagagac aacccattag aagcgatcgt
      241 aacagacttg acttatgtac gagtcgggaa aaaatggaat tatgtctgtt tcattttgga
      301 tctgttcaat cgagaaattc tcggctattc ttgtggagaa cataa
//
LOCUS       DAZAOD010000262          333 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.287, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000262 DAZAOD010000000
VERSION     DAZAOD010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.287"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          113 a           56 c           55 g          109 t
ORIGIN      
        1 aattggagtg gtagttaatt agtgacttat ttttgatttt atagcactga tactataaaa
       61 tatagatatc atcatattac acaatcttaa tactaactta aaaaatatct cctttcacaa
      121 gtatggtgat aaaattcgtt ccgggctacc tttttaggta gcctacttta atctttatac
      181 ctttctggat caacgaaagt atactttata tagtcataac gccgatgatc gctacgtgcg
      241 tccggcacgt cagtcatgaa tcggctacac tagactagac agaaaaaata aggtgtgtag
      301 aataataaaa aacacactgg aggatttttc atg
//
LOCUS       DAZAOD010000263          312 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.293, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000263 DAZAOD010000000
VERSION     DAZAOD010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.293"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(69..142)
                     /locus_tag="ACHDPO_003023"
     tRNA            complement(69..142)
                     /locus_tag="ACHDPO_003023"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(106..108),aa:Ile,seq:cat)
BASE COUNT           99 a           58 c           62 g           93 t
ORIGIN      
        1 aaagctttag cttgtataat actcttcaaa aaaattctaa cacagaacga ttcaaatggc
       61 tacgttaatg taccctgtag gactcgaacc tacgaccgga cggttatgag ccgtctgctc
      121 tgaccaactg agctaagggt actggttgtt gccacataaa gccataaaca atcaaccagt
      181 agaatgtgtg gcaacaaacc tgttatcgca tagcttggag tgtgactatt tatgggtgat
      241 agtgaagata tgcgataaca tcactatttt atcgaataat ttttatagtt gtcaatatag
      301 ttatgtactg ct
//
LOCUS       DAZAOD010000264          309 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.denovo.294, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000264 DAZAOD010000000
VERSION     DAZAOD010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.denovo.294"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..309
                     /locus_tag="ACHDPO_003024"
                     /pseudo
     CDS             1..309
                     /locus_tag="ACHDPO_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          122 a           61 c           59 g           67 t
ORIGIN      
        1 attcaaaaga attcaaacaa caaatcgtcg atctctatct cgctggtaag cctcgcgcag
       61 aaattattcg agagtatgag cttacgcctt cttctttcga taaatggatg aagcaagcac
      121 aatcaacggg ctcattcaaa gaaagagaca acttaacacc agaacaagca gaattgatcg
      181 cactaagaaa gaaaaataag caactcgaaa tggagaatga tattttaaag caagcggcgc
      241 tgatattcgg acgaaaagac aagtaattga tgccaacaag cataaatatt ccatatcagc
      301 gatgtgcaa
//
LOCUS       DAZAOD010000265        36406 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.013, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000265 DAZAOD010000000
VERSION     DAZAOD010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.013"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            948..1262
                     /locus_tag="ACHDPO_003025"
     CDS             948..1262
                     /locus_tag="ACHDPO_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370553.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(1315..2088)
                     /locus_tag="ACHDPO_003026"
     CDS             complement(1315..2088)
                     /locus_tag="ACHDPO_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370554.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            2193..2438
                     /locus_tag="ACHDPO_003027"
     CDS             2193..2438
                     /locus_tag="ACHDPO_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFN3370555.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            2594..3445
                     /locus_tag="ACHDPO_003028"
     CDS             2594..3445
                     /locus_tag="ACHDPO_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFN3370556.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            3478..4155
                     /locus_tag="ACHDPO_003029"
     CDS             3478..4155
                     /locus_tag="ACHDPO_003029"
                     /inference="COORDINATES: protein motif:HMM:NF024685.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFN3370557.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPHY
                     CIMRKIL"
     gene            4643..5608
                     /locus_tag="ACHDPO_003030"
     CDS             4643..5608
                     /locus_tag="ACHDPO_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HFN3370558.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            5630..5842
                     /locus_tag="ACHDPO_003031"
     CDS             5630..5842
                     /locus_tag="ACHDPO_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFN3370559.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            5917..6393
                     /locus_tag="ACHDPO_003032"
     CDS             5917..6393
                     /locus_tag="ACHDPO_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HFN3370560.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            6390..8198
                     /locus_tag="ACHDPO_003033"
     CDS             6390..8198
                     /locus_tag="ACHDPO_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFN3370561.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            8275..8490
                     /locus_tag="ACHDPO_003034"
     CDS             8275..8490
                     /locus_tag="ACHDPO_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family mobile element protein"
                     /protein_id="HFN3370562.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            8582..9445
                     /locus_tag="ACHDPO_003035"
     CDS             8582..9445
                     /locus_tag="ACHDPO_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HFN3370563.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            9482..10018
                     /locus_tag="ACHDPO_003036"
     CDS             9482..10018
                     /locus_tag="ACHDPO_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MT-A70 family methyltransferase"
                     /protein_id="HFN3370564.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            10032..10454
                     /locus_tag="ACHDPO_003037"
     CDS             10032..10454
                     /locus_tag="ACHDPO_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HFN3370565.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            10384..12783
                     /locus_tag="ACHDPO_003038"
     CDS             10384..12783
                     /locus_tag="ACHDPO_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HFN3370566.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            12815..14806
                     /locus_tag="ACHDPO_003039"
     CDS             12815..14806
                     /locus_tag="ACHDPO_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFN3370567.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            14829..15080
                     /locus_tag="ACHDPO_003040"
     CDS             14829..15080
                     /locus_tag="ACHDPO_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HFN3370568.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            15070..16299
                     /locus_tag="ACHDPO_003041"
     CDS             15070..16299
                     /locus_tag="ACHDPO_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1107 family mobile element protein"
                     /protein_id="HFN3370569.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            16296..18377
                     /locus_tag="ACHDPO_003042"
     CDS             16296..18377
                     /locus_tag="ACHDPO_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFN3370570.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            18526..22446
                     /locus_tag="ACHDPO_003043"
     CDS             18526..22446
                     /locus_tag="ACHDPO_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodL domain-containing protein"
                     /protein_id="HFN3370571.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            22447..23391
                     /locus_tag="ACHDPO_003044"
     CDS             22447..23391
                     /locus_tag="ACHDPO_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370572.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            23395..23598
                     /locus_tag="ACHDPO_003045"
     CDS             23395..23598
                     /locus_tag="ACHDPO_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HFN3370573.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(23898..24134)
                     /locus_tag="ACHDPO_003046"
     CDS             complement(23898..24134)
                     /locus_tag="ACHDPO_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFN3370574.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(24317..24688)
                     /locus_tag="ACHDPO_003047"
     CDS             complement(24317..24688)
                     /locus_tag="ACHDPO_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HFN3370575.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(24685..26013)
                     /locus_tag="ACHDPO_003048"
     CDS             complement(24685..26013)
                     /locus_tag="ACHDPO_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFN3370576.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(25974..26303)
                     /gene="mobC"
                     /locus_tag="ACHDPO_003049"
     CDS             complement(25974..26303)
                     /gene="mobC"
                     /locus_tag="ACHDPO_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFN3370577.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(26561..26931)
                     /locus_tag="ACHDPO_003050"
                     /pseudo
     CDS             complement(26561..26931)
                     /locus_tag="ACHDPO_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            27076..27261
                     /locus_tag="ACHDPO_003051"
     CDS             27076..27261
                     /locus_tag="ACHDPO_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFN3370578.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            27419..27586
                     /locus_tag="ACHDPO_003052"
     CDS             27419..27586
                     /locus_tag="ACHDPO_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370579.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            28204..28863
                     /gene="vanR-B"
                     /locus_tag="ACHDPO_003053"
     CDS             28204..28863
                     /gene="vanR-B"
                     /locus_tag="ACHDPO_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
                     /protein_id="HFN3370580.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            28866..30227
                     /gene="vanS-B"
                     /locus_tag="ACHDPO_003054"
     CDS             28866..30227
                     /gene="vanS-B"
                     /locus_tag="ACHDPO_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HFN3370581.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(30318..31619)
                     /locus_tag="ACHDPO_003055"
     CDS             complement(30318..31619)
                     /locus_tag="ACHDPO_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFN3370582.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            31898..32704
                     /locus_tag="ACHDPO_003056"
     CDS             31898..32704
                     /locus_tag="ACHDPO_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HFN3370583.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            32722..33429
                     /locus_tag="ACHDPO_003057"
     CDS             32722..33429
                     /locus_tag="ACHDPO_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HFN3370584.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            33426..34397
                     /locus_tag="ACHDPO_003058"
     CDS             33426..34397
                     /locus_tag="ACHDPO_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HFN3370585.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            34390..35418
                     /gene="vanB"
                     /locus_tag="ACHDPO_003059"
     CDS             34390..35418
                     /gene="vanB"
                     /locus_tag="ACHDPO_003059"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HFN3370586.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            35424..36032
                     /locus_tag="ACHDPO_003060"
     CDS             35424..36032
                     /locus_tag="ACHDPO_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HFN3370587.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(36098..36271)
                     /locus_tag="ACHDPO_003061"
     CDS             complement(36098..36271)
                     /locus_tag="ACHDPO_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370588.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         9745 a         8758 c         9401 g         8502 t
ORIGIN      
        1 acaaaaatat gtaattctat tatcactatt aaagagaaag ttggagcgga atataaagaa
       61 aagagaaaag taattaaacg caaaaaaatg tagaacttaa aaaatataaa gaggaacaac
      121 cgttaaaatt aggaatgatg ttgtgtaaac attataattg ctatgatata aatgaagtgt
      181 taaagaaagc aaatttaaac caattttgtg aacagaaaag ccttagtcac tatgaccaaa
      241 actacggacg aaactatgac caaaagtagg tactaaatta tgaccgaaaa taggtccaaa
      301 atggattttt ttatgatatc aaaaattatg aaatgatttt gaaagaaaac cagttggcac
      361 agccaactta gccaccttcc tgtaggaagg tgctatcagt tttcccttat gctcttttct
      421 ttcttttttg tttcatatgt caaatgccat tttgaaatgt accatcttaa gaaatttatc
      481 cttaaaaaca attgcgttat tggataaaaa gatgctacat tatcttaaaa aaggaatcaa
      541 atatgatgaa tttagtggct agcatatcgt gtgattaaga tactttatag tgtaagttga
      601 aggagaaaaa atatttaaaa tatacttccc atttcagtgg gaagtaaaat taatcttgtt
      661 gtttctacta gtaatgtatc tttttggaaa ctatgtaacg atgtaaacaa gatttttttc
      721 agaagaaaaa acgataaaag ttgtgataaa cgatttaaaa aataggagaa aatatatcaa
      781 gcgcatggta tgaaacgcac atttaaaaag attcgactaa ctaaaaaaat aagtttacaa
      841 agcattgttg tgtattacaa gtgatctata cactgaaaaa tgatagagaa aatctgatac
      901 gtccgcaaca atggacaatt gaaaatgaaa gtgaggaaat tggaagaatg gctgatgaaa
      961 ataaagttgt tccgcttgaa acactagtga taaataagga agagtttgag caactttttc
     1021 ttgatttttt tgttcaatat gacaggattt atgattttag ttcgtcacta gatttatttg
     1081 aattagaggc agaaataata gaaaacagtc gagaggagaa tggtaaaatc atcatttcag
     1141 tagaaaaatt caatgaatta ttctcagaaa catttgaaat agatacagat tattatcaac
     1201 cacaagaagt tttccaatca tttagaaatc agattattcg ctcaggtaag accgtaaact
     1261 gaaaaacaat aaaagaaacg ttgaaagaat aattattcct tcaacgtttc ttttttagaa
     1321 tgttttaatg accaaagcag tttcattgtc aggcttaggt aattcatgaa atcccgtatt
     1381 tatagtgctc aattgatcaa ctaaccatgt tttacttttt gaattgtaga taaatctaaa
     1441 attaatatcg ttattatcgt gttgaagggg cgtctccaaa taatctgctg tatattcata
     1501 gtcaacgtaa cctgctaata caaaagagag tatcccttta tttaatgtta gatttaatgg
     1561 ataatcatac gactttattt ttttcaactt catattgtac atatcttcag ccataaaagt
     1621 tgagttcgtg atttcatctt gggtctcatt aaaaaagtta tccgaataat cgcttatttt
     1681 tgaaaagtct ttattggcac cagcctcaaa aaattgttca actttttcag tataaagttg
     1741 tgctaacgct cctttttcaa tattaacttt aatattttca tgtctatcaa tttgtgtgct
     1801 gttcagtaag ggaagatcag cttttagttt tatatcgtct tgatttcttt caatttcaat
     1861 tggcaaaatc ttttcagtag attcagtttc tgataaagga acatctagtt ttttatcatg
     1921 ataataagct tcaaatccat ctggaaccgg aaaaaaatgt attgggtaat tcttttctga
     1981 ggttgttgta ctagtttccg tacttgtaga acttgtgtca gaagtggtac acccgcttat
     2041 agttccgatg agtaaagcgc aagttagaat gattgcaaat ttcttcaaaa aaattcctcc
     2101 ttaaaattga atatggacta atactagtcc cattgtagca taccgaatct ttaagattaa
     2161 taagaaaaag gactaatttt agtccaaaag gtgtgctatt cttgaaagag gaaaaaatta
     2221 ttgataaaga aaatgtaatc ggtagcaata ttagacgagt ccgattagaa aaaggaattg
     2281 gtcaaaccga gctgattaga gacctacagc ttcgtaaaat tgctataact agggaaacgt
     2341 tggttaagat tgaaggtggc cgccaacaca ttaagttgga tcaattgaaa gccatcaaag
     2401 atattctaca ggtgtcttat gaagatttgc ttcaatgact acttgtagtc atttcgtttg
     2461 aaattattat gttacaccct tatgtgtcac gaagaaatac tggtataata atgaatggga
     2521 tatgtaacga tagggtatac tgttatgttg cctaataaat tgtggatcaa aatacaagaa
     2581 tggagggata tccttgtata aggcatatga attggatttt acaaatgctg acttaaatgc
     2641 attctcctca agctcgcaat catatacaca tgtagtaaat caaatagatc acaaccaaaa
     2701 atctattaac aagagaatag aaaatctatt tgaaagtgaa aatgatttag ttgattatta
     2761 ttctaaggac agcaaaattc tagatgcaga cgaaattatt aaagattggt ttccaactat
     2821 aaaagcagat atttttatat ctcactctca tgctgatgaa aaattagcta tacgttttgc
     2881 atcatggcta tttgaaaatt ttggtcttac tgcatttatt gattcttcgg tttggggata
     2941 cagttctgat ttattaaaaa aaatagacca aaaatattgc tataaggaac aaacaaaaac
     3001 atatgattat gataaaagaa atgtaacaac tagtcatgtt catatgatgc tttctacagc
     3061 tttaaataat atgattgata gtacagaatg tctgtttttt cttaatacac ctaattcaat
     3121 tagtttgagc aatgaaatca ctaatgaaca gaaatttacg tattcgccat ggctatatag
     3181 cgaactgacg acagcttcaa tagtggaaaa aaagaatcca cgattggaaa gtaatcctca
     3241 aatgagcacc gaggatgtta gaagcattat aaagcactat tcttcgcaag aaaatctgca
     3301 aataaaatat tctttaaatt taagtgaatt aacttattta cgaaaagctg atttgaaaaa
     3361 atgggcttta gatgctgtgg aatgcactaa aggaagtaat acattagata ttttatataa
     3421 aaacaccatt ttcactaatc tctaatcaat ttactgaatc gaaaggaacc gggtagaatg
     3481 gataagaaag ttttaataaa gaggttctct gaagctattg aaaaaggaaa tgcagcaata
     3541 tttgcaggtg caggattatc gatgtcacaa ggatatgtaa gttggccgga actacttaat
     3601 gatcctgcaa cagaaatcgg gttggattct aaaaaagaaa cagacttagt tactctggct
     3661 caatattata aaaatgaaaa tggtggatca agaggaattt tgaatcagat acttatggat
     3721 aattttggtg aagaattaga aatatctgaa aatcatcgaa tactagcaag tttacctatt
     3781 gaaacttatt ggacaactaa ttatgatcat ctaatagaaa aatcaatccg agaagcttat
     3841 aaaaaccctc aggttaagaa aaattatact cagttagcaa caactaatcc aaatgtggat
     3901 acaattgttt ataaaatgca tggtgatata gatgatgtca gttcgacagt aataacaaga
     3961 gatgattatg aaaaatatga tgattcgtac gcgttattta aagaaacttt aaaaggagat
     4021 ttgttaacaa aaacttttct ctttttagga tttagtttta cagaccctaa tttagaaaga
     4081 attttatcag atataagatg ggttttgaga gaaaaccaaa gacctcatta ttgtataatg
     4141 agaaaaatat tatagaaaaa attttaggtt atcgctgaaa gccccggaaa tacgggcatt
     4201 tcgcaggata tgagaactca atttactacc aatttactac tttcggattg agccgcatat
     4261 atgctgaacc atactgctaa tacccgccac cccaaatacg gcacatcata aattgaatac
     4321 gacaccgtaa acgcggcgtt cctctttccc gtcatgggag aacaggacgc cgctttttta
     4381 tgcccaaata gagaaaggag gcgacgccat gctatttact tccggccctg accgggcgtt
     4441 tgaacggctg atgcaggaaa agcccggttt cgatcactac gacggcggcg gggcggacgc
     4501 gccggaggat tgcggcacct gccgatttta ccgcccggat tggaaatatc aattctgcca
     4561 gtttgcagag tgtccctatc agccgggcaa gctgaccgac tatgcagcgg tcaaattcac
     4621 agtgaaagga gcgaacaacg ctatggcagt tttccgtgtg gaaaagaaca aaggctatac
     4681 ggtgatgtca aatcaccacc tgcggaataa gaacctgacc ttaaaggcca agggcctgct
     4741 gtcgcagatg ttgtccttgc cggaggattg ggactatacc ctaaaaggac tgtcctatat
     4801 caaccgggaa agcatcgacg cgatcaggac agcggtatgg gagcttgaaa aagctggata
     4861 tatccggcgt gagcagggcc gtgacgcaaa aggcaaaatg gccgatatgg tctataccat
     4921 ctacgaacag ccggtattgg aaaacccggt attggaaaat ccaacatcgg ataacccggt
     4981 gttggaaaat ccgacatcgg ataatccggc gtcggaaaat ccaacgcaat taaataaaga
     5041 agtacaaaga actgacttat caaaaaaaga aaaaataatt acagatggac aaagtaccca
     5101 ttccattcct atcccatccc cgacccctgc ccctatggag ggcgaggcag cggctacgcc
     5161 gccggaacgg aaaaggacag gaaaggatga ggctgtacgg atttatcggg aaatcatttt
     5221 ggagaacatc gagtatgcct atctcattca ggacaggagc attgaccgtg aacagcttga
     5281 cgaaatcgta gacctgatgc tggaaaccgt ctgcaccgcc cgaaagacaa tccgtgtcgc
     5341 cggggacgac taccctgccg agctggtgaa atccaagtac atgaagctga ccggcgaaca
     5401 tatccgcttt gtccttgact gtctgcggga gaacacaacg aaagtccgca atatcaaaca
     5461 atacctgcgg gctatgctgt tcaacgcccc cagcaccatt tccaactact acacggccct
     5521 tgtcgcgcac gacatggcac agcccgattg gggaaagcct aaatccggcc tgccggacta
     5581 ttcctgcggc gagggcgaaa gcctgtaacg agaaaaggag gacgacccta tgaagcaggg
     5641 cgcattgatt tttgacgagc gaacagaccg ttacgacatc cgctttgatc tggccgacta
     5701 ttacggcggc ctgcattgcg gggagtgttt cgacgtgatg atcggcggca aatggaggcc
     5761 cacccgcatt gaaatggccg aaaactggta tcttgtcggc atccgggccg acgacctttc
     5821 cggcctgcgg gtgcggattt gacctatatc tacctgcggc gtctggtggt tccgccttag
     5881 acgccgcttt tgactttctg acaaggaggg atgcgattgc aggaagaagt tactcaaaag
     5941 accattgccc tgtccatgaa aacgggcaag ctcacggctc aagtgctgca agcggcgctg
     6001 aaaaagtacc tgcaacaccg ggccaagggc aaaaacacgc tgcaccacgg ccagcagagc
     6061 ctaaagcagc ttaaaaagca tggggctgat ctctccaaca ttgagatcac cgaggccaac
     6121 attggagcgt tcaagccatg cgccaagaaa tacggcgtgg attttacctt acgaaaagat
     6181 aagaccaccc agccgcccca ctacgttgtg attttcaagg ccaaggatgc agataacctt
     6241 gatctggcgt ttcgggagtt taccgccaag acgctttcca aggagcagcg gccctctatc
     6301 cgcaaggttt tgtccgctgt gaagcaaaag gcggcggccc agaccaagca gcgggccaag
     6361 gagaaaatca aggaaagggg gctggaactg tgaagcctga cgtaaagaaa ttgctgatcc
     6421 tgaacctccc gtatctgatt tttgtgtacc tgtttgcgaa atgcggggag gcgtaccggc
     6481 tggccgctgg tgctgacctg tcggggaagc tcctgcattt tgcggatggt tttgcggcgg
     6541 cttttgccaa ccctctgcca agcctgcacc tgtttgacct gtgtatcggt atcgccggtg
     6601 ccgtgatcgt gcggctggtg gtgtactgca agagcaagaa cgtgaagaaa taccgcaaag
     6661 gcatggagta tggcagcgcc cgctggggga cggccaaaga catagcgcct tacatcgacc
     6721 ccaagtttga aaataatatc ctgctcaccc aaacggaacg gcttaccatg accggcaggc
     6781 ccaaagaccc caagacagcg cggaataaaa acgtgctggt gatcggtggc agcggttcag
     6841 ggaaaacgag atttttcgtg aaacccaacc tgatgcaatg ctttccgacc acggactatc
     6901 cgacttcgtt tgtggtgaca gatccgaaag gcactttggt tctggaaacc ggcaggatgt
     6961 tccagcaggc gggctaccgc attaaaatcc tgaataccat taacttttcc aagtccatga
     7021 agtacaaccc ctttgtctac atccattcgg aaaaggacgt gctaaagctg gtaaataccc
     7081 tgatttccaa caccaagggc gagggggaaa agtcagcgga ggatttttgg gtgaagtcgg
     7141 aacggttgtt ttattcggcc ctgatcggct atatctggta cgaggcccca gcggaggaaa
     7201 tgaacttctc aacgctgctg gaaatgataa acgccagtga agcccgcgag gacgacccgg
     7261 agtttcaaag ccccgtcgat ctcatgtttg agcgtttgga gcagaaagac cccgaccatt
     7321 ttgcggtgcg ccagtacaag aaattcctgc tgtccgcagg caagacccgt tcttccatcc
     7381 tgatttcatg cggtgccaga cttgcgccct ttgacatccg ggaggtacgc gagctgatgg
     7441 aggacgacga aatggagctg gacaccatcg gggacgaaaa gacggtgctg tatctcatta
     7501 tgagcgatac ggacacgacc tttaatttca ttctggctat gctccaaagc cagctaatca
     7561 acctgctttg tgaccgggct gatgatgtgt acggcgggcg gctgcctgtc catgtacgcc
     7621 tgattttgga tgaatttgcc aacattggcc aaatacccaa tttcgataaa ctcattgcca
     7681 ccattcgaag ccgtgaaata tcggcctcta ttattttgca gagccagtcg cagctaaaag
     7741 cgatttacaa ggacgccgcc gagatcattt cggataactg cgatagtgtg cttttcctta
     7801 gtgggcgcgg caaaaatgcc aaggagattt ccgatgcgct ggggaaagaa acgattgaca
     7861 gtttcaacac cagcgagaac cggggaagcc aaacgtccca cggattgaac tatcaaaaat
     7921 taggaaagga gttgatgtcc caagacgaaa ttgccgtgat ggacggcggc aagtgtatct
     7981 tgcagctacg gggtgtgcgc ccgtttttat cggagaaatt cgatattacc aagcatcccc
     8041 ggtacaaata ccttgccgac gccgacaaga agaatacctt tgacgtggac agatttttga
     8101 ctatcacgcg ccggaaacgg cagcaagtgg taacgcagga tgaagtattc gacctgtatg
     8161 aaatcgacct gtcggacgag gacgccgccg ctgaataaac agcggctttt ttcattccaa
     8221 caacaaaatc aaaaaatcat tatgagccgg aaaccggcag aaagaggtaa atttatggca
     8281 ttttttaatt ccgcagttac tactttgcag actatcgtga tcggactggg cggcgctctg
     8341 tgcgtatggg gcggcatcaa tctgttggag ggatacgggc aggacaatcc gggggcaaaa
     8401 tcgcagggtg tcaagcagct tgtcgctggc ggcggcgtgg ccctgatcgg tgtcactctg
     8461 gttcccctgc tgtccgggct gctgggctga tcctggcctt tgtccctgtc caaaccctta
     8521 actaatcgcc tccgcgtcct cccggccaga ccgggagggc gcgggaaagg aggtgctacc
     8581 cgtgattagt gaaatcattg aagaatggat aaaaggcatc ctcatggacg gtatcacggg
     8641 caacctgtcc gggctgttcg atacggtaaa tgccaaagtc ggagaaatcg ccgccgacgt
     8701 gggacgaacc ccgcaggcat ggaacagcgg tattttcaat atgctgcaca gcctgtcgga
     8761 aaccgtgatc gtccccatag ccggggccat actcgccctt gtcatgtgct atgagcttat
     8821 ccagatgata acggaaaaga acaatatgca cgactttgac agctccatgt tcttccgctg
     8881 gatattcaaa tccgcgtttg caatcctgat cgtaacgaac acatggaaca tcgtcatggg
     8941 cgtattcgac gccacccaaa gcgtcgtcaa tcaaagcgcc ggtgtgatta tcgggcagac
     9001 atccattgat tttaacaccc tgataccaga ccttgaaagc caattggagg ctatgagcgt
     9061 gggcgctctt ttggggctgt ggttccaaac ccttgttgtg ggcctcacca tgaatatcct
     9121 ttccatctgc attttccttg tgacctatgg ccgcatggtg gaaatctatg ttgtcacgtc
     9181 gctggggcct atcccccttg ccacaatggg caacgcggaa tggcgcggca tgggccaagg
     9241 gtatctgaaa tccctgctgg cgctgggctt ccaagccttt ttaatcatgg ttgtggtggg
     9301 tatctacgcg gtgctgatac agaatatcgg ttccgcttcc gacatatccg gcgcaatctg
     9361 gggctgtatg ggctatacgg tgctgctgtg cttctgcctg ttcaagaccg gcagtatatc
     9421 aaaggccgta ttcggggcgc attgatccca aaatccaagc atacacagga ggaacttgtt
     9481 tatttcaacg tacaacatca tttacgctga cccgccgtgg cggtatgact gcaaaaacgt
     9541 acagggcgca gcggaaaatc actattccac catgagcatt gacgagctgt gcgccctgcc
     9601 ggtggaacgg ctggcgtcca aagactgcct gctgtttttg tgggccacat tccccatgct
     9661 gccggaagct ctgcggttaa tcaaagcgtg gggcttttca ttcaagaccg tggcttttgt
     9721 atggctgaaa cagaaccgta aaagccttac atggttttac gggctgggcc gctggacaag
     9781 gggaaacgcg gaaatctgcc tgctggcaac acacggcaag ccgaagcgtc gttctgcctc
     9841 tgtccatcag tttattatca gcccgattga acaacacagc aaaaagccgg atgtgacccg
     9901 tgaaaaaatc gtagagctgg cgggcgattt gccccgcgtg gagctgtttg ccagacagaa
     9961 aacccccggc tgggacgtgt gggggaacga ggtggaatgt gaccttatcc tgacgtgaaa
    10021 ggaggtgcca aatggcttat gtaaccgtcc ccaaggactt aacccatgtg aaaagcaagg
    10081 ttgtgtttgg gcttaccaaa cggcaactga tctgtttttc cggggcgctg gtgatcggcg
    10141 tccccttata ttttctcacc cgtgactatc ttaccaacag cgcggcggcc ctgctcatgg
    10201 tatttgccat gctgccgggc tttttgcttg ccatgtacga gcgtcacggc cagccccttg
    10261 aagtggtgat tatgcagatc atccagtgct gcttcatcca gccaaaggag cgtccctatc
    10321 agaccgacaa cacctacacc gcccttgtgc ggcaatacca gatggaacag gaggtaaagg
    10381 ccattgtcca aaaaggaaat cccaagagaa accgaaaaaa caaagctgac ccgcgcccag
    10441 cgaaaagaaa ttgacgcggt aatccgtaaa tataagggcg acggcaggcc ccacacggcg
    10501 cagcagagca tcccctacga ggtcatgtac ccggacggcg tgtgccgggt atcgcccggc
    10561 gtcttttcca agtgcattga gtttgcggac atcagctatc agcttgccca gccggacacg
    10621 cagacggcta tctttgaaaa actgtgcgac ctgtataact atgtggacgc ctccattcat
    10681 atccagtttt ctttcctcaa tcggaaagtt gacccggtgc agtacgccaa gagctttgag
    10741 atcgcgccgc agggggacga cttcgacgac atccgggccg agtacaccgg cattctgcaa
    10801 aagcagcttg caaacggcaa caacggcatg gtaaagacca aatacctgac attcaccatc
    10861 gaggccgaaa gcgtgaaagc ggcgcgagcc agattgaagc gcatcggctt tgacctgtta
    10921 ggctatttca agagcatggg ggccgtagcc catgtgatgg acggctggga acggctgaac
    10981 ctgctgcatg gcgtgtacca cccggacggc gagatattca attttgactg gaagtggctg
    11041 gccccgtccg gcctctccac caaggatttt attgccccgt cctccctgtg cttcggcaat
    11101 gcaaagacat tcggcatggg cggcaaatac ggcgcggtaa gtttcctgca aatcctgtcc
    11161 ccggagctgt cggacgatat gctggccgac ttcctcaata cggaaagcgg tgttttagtc
    11221 aatctccatg tgcaggccat tgaacagacc aaggcgatca agaccatcaa gcgcaaaatt
    11281 accgaccttg acgctatgaa gattgcggag cagaaaaagg ccgtccgcag cggttacgat
    11341 atggacattc ttcccagcga ccttgccacc tacggcgagg acgccaagaa gctgctgaca
    11401 aagttgcaga cccgcaatga acggctgttc cagttgacgt tccttgtcct caacgtggcc
    11461 gacaccaagc aaaagctgaa taacgacgtg ttccaagccg caggcgtggc ccaaaagcat
    11521 aactgtcccc ttgtccggct ggactaccag caggaacagg gccttgcaag cagcctgccg
    11581 ctgggcgtca atcagatcaa gatacagcgc agccttacga cttccagcgt ggccgtgttc
    11641 gtcccctttg tgacgcagga gctttttcag ggcggcgcgg ccatgtatta cggcatcaac
    11701 gccaagtccc gcaacatgat tatgctggac aggaagcagg cccgttgccc caatgccttg
    11761 aagctcggca cccccggcag cggcaaatcc atgagctgta aatccgagat cgtcagtgtg
    11821 ttcttaacga cgcctgacga tatttttatt tcagacccgg aggccgaata ttaccccctt
    11881 gtcaaacggc tccacggaca ggtaatccgg ctgtcgccta ccagcaagga ctttgtgaac
    11941 ccgctggaca tcaacctgaa ttattcggag gacgataacc cgctggccct gaaatccgac
    12001 tttgtgctgt cgttctgtga gcttgtcatg ggcggcaaga acgggctgga agccattgaa
    12061 aagaccgtga tagaccgggc tgtgcgcgtg atctaccggc cctatctggc agacccccgc
    12121 ccggagaata tgccgatcct gtccgacctc cacaaagcgt tgttagatca gcatgtcccg
    12181 gaggctgacc gggtggcgca ggcccttgac ctgtatgtgt ccggctccct gaacgtattt
    12241 aaccaccgta ccaacgtgga catcggcaac cggcttgtgt cctttgacat taaggagctg
    12301 ggcaagcagc tcaaaaagct ggggatgctc attgtccaag accagatatg ggggcgcgtc
    12361 acggccaacc gaagccaagg aaaggccaca tggtattttg ccgacgagtt ccatttgctt
    12421 ttgaaagagg aacagacggc ggcctattct gcggagattt ggaagcggtt taggaaatgg
    12481 ggcggcattc caacaggtgc cacccagaac gtcaaagacc tgctttcctc cccggaaatt
    12541 gaaaatatcc ttgaaaacag cgacttcatt acgctgctca atcaggcgtc cggggataga
    12601 aaaatccttg cggaacgctt gaatttgtcc accgaacagc agaagtacat cgacaattcc
    12661 gaacccggcg agggcctttt gatctttgaa aacgtggtgc tgccctttac caaccccatc
    12721 ccgcacaaca cccagcttta caagattatg acgacccgct taaacgaggt ggcgggagta
    12781 tgacccggcg acgccacaaa ggaggtgaac caccatgaaa gagctgaaag ccaaggcgaa
    12841 agtgacgcag gccatgaccc gcgacgggct gacgctggaa aatcaggcca ccggcgaggt
    12901 ggagaacatt tccagccggg aggccgaaca ggatttgtcc gcgccggggc cgggcggcac
    12961 cgccgataag ctgctggaac gggccgacgc catccatgac ggccataagg ccaagaaagc
    13021 cgcgaagcag gccggggctg tggccgccga gggggacgct gccctgcacc ggccatccgc
    13081 ccggctccaa ctgtcggagg aagaacgggc cgacccggat ttacagccct atatccgaaa
    13141 atcggacaaa cgggccgata agctggataa ggcccgcgcc gccatcccca agaagcgcgt
    13201 cccggtcaag gaaaccgtct ttgacgaggc aagcggcaaa gcaaagaccg tcctgcactt
    13261 tgacaaacag gacaaggggc ctccctccct gaaacccaat ccggcaggcc gtcctgtttc
    13321 cgaggttttt ctattcggcc acgggaaaat ccatgaagtc gagcatgaaa acgtgggtgt
    13381 ggagggcggc cataaggggg aggaacttgc cgagcggcag gccggaaaag ccatccgcag
    13441 caccatccgg caccacaggc tgaaacccta ctgggacgcg gaaaaggccg agcgcaggct
    13501 attgtctgcc aacgcggagt atttctacca gaaatctttg cgggataacc cggagatcgc
    13561 acaggcggcc agcaacccca tttcccggtt ctggcagaaa cagcagatca agcgccagta
    13621 cgccaaggcc gcccggacag cgggccagac cgcaggcgcg gcggcacagg gcgcggccaa
    13681 gacagccggg gcctccacga aagcggccaa ggccgcagcc aaagaaagtg aacgggcggc
    13741 ctcctttgtg gcccgccact ggaaaggggc gctggccgtc cttgtgttgg ggcttttgat
    13801 gctgcttatc atcggcggct tacagtcctg caccgccatg ttcggcagcg ccggaagcgg
    13861 catcacggcg tcctcttact tttccgagga tagcgatatg ttggccgccg aggacgccta
    13921 cgcggagctg gaagccgagc tgcaagacta tctggacaac tacgaggcca cccatgacta
    13981 tgacgaatac cattttgacc ttgacgagat cagccatgac ccctatgtgc tgatttccat
    14041 tctgtcggcg ctccatgacg ggatatttac catcggggag gtacagggtg atttgtccat
    14101 gctctttgac aagcaatata tcctgacaga aaacgtcgtg gtagaaaccc gttaccgcac
    14161 cgaaaccgat acatggacgg acgcggaggg caacacccat acagacacct accaagtgcc
    14221 gtatgactat tacatctgct acgtcacgct ggaaaacttc gacctgtccc atgtgccagt
    14281 ctatatcatg gacgaggaaa cgctaagttt ctattccctg tatatgtcca cgctaggaaa
    14341 ccggcctgat ctgttttccg gcagccagta ccccaacgcc tccaccctga cgccgccgac
    14401 ctactacgac gtacccccgg aggctttgga ggatgccacc tttgccgcca tgctcaaaga
    14461 ggcggaaaaa tatatcggtt atccctatgt gtggggcggc agctctccca gcaccagctt
    14521 tgattgcagc ggcttcattt cgtgggtaat caatcatagt ggatggaacg tgggacggct
    14581 gggggcgcag ggcctatata acatctgcac ccctgtttcc agttcgcagg ccaagcccgg
    14641 cgaccttgta tttttcaagg gaacctacga cacccccggc gtgtcccacg tcggcctgta
    14701 tgtgggcaac aatgtgatgc tgcattgcgg gaacccgatt tcctacacga accttacttc
    14761 aaactactgg caatcccatt tttacagtta cgggcgttta ccttaacgcc agaaaggagc
    14821 tttcaattat ggcaaccaaa cttgaccgca tcgaaaagga catccagaaa accaagtcta
    14881 agatcgcgga gtttcagaaa cagcttcggg agctggaaac gcagaaaacc gaacaggaga
    14941 atttgcagat catccagctt gtgcgcggca tgaacatgaa gccggaggaa tttgccgcgt
    15001 tcttacgcag cggcgcaatg caggccgccc ctgccgcaac cccttaccat gaacaggagg
    15061 acaatgccca tgaagaataa gaccagacgg atttcccgta ttctccccgc acttctggcc
    15121 gtgatgctct gcgtcacggc ctttcccgtt accgcccttg caggcggcaa tgacccggca
    15181 ccggccccgc tgccggaggc tacaaccgaa cccgctacgg gcggtttgga gcctgaaaca
    15241 gacgaaaccg gcaccgccac ggacgggaca gaaaccgagg ccgaaaaaga taccggccct
    15301 ctgaccggca aggacatcac cgacctgttt tccgcgctgt tcggttccaa ggtgagcatt
    15361 gccgccacgg acgacggcat ccagatcacc accggcaccg acaaaaaaga acctgaacag
    15421 accggcaccg tcaccaccaa cggcggcagg ctgaatgtcc gcaccggcgc ggggcttgac
    15481 aagaccgcgt tcacccagct tcccaatggg acgacggttg aggtagtcgg cacagacggc
    15541 gactggatta aaattctctt gccggagcgc atcggctatg tccattccga ctatatgacc
    15601 gtcagcgaaa aggaagtagc ggctaccggc gagggcggtt tttccctctc cattgacccg
    15661 gaggaaattg cttctctgct ggaactgttc aatggcggcg gggccagcgc cgccctgtcc
    15721 ccggacggga acctgtcact gattgacgac atcggcagcg ccgcgaaaaa tggcaagcag
    15781 tttatcaccg tggaaaccaa aaacggcaat gtgttttatc tgattattga ccgggacgac
    15841 gagggaaaag aaactgtcca tttcttaaat caggtggatg aagccgatct gctgacgctg
    15901 atggaggacg gggaaaccgt cacccccgct gctgtctgct cctgtaccac gaaatgcaag
    15961 gccggggctg tgaacacgaa ttgcccggta tgtaaaacca acctgaccga gtgcagcggc
    16021 ccggagccgc aggaacccca gccggaggaa cccgaagccc cggaggaaga acccaagggc
    16081 ggcgcgggcg gcctgatcgt gttcctgctg gtggcgctgg cgggcggcgg tgcggccctt
    16141 tactatttca agttcaaaaa gcccaaggct gaaaccaccg gcagcgacga tttgggcgag
    16201 tatgattttg gggaggacga ggatttggag gacgaggaac ccgaaaccga gtttgacccg
    16261 gaagctgatt ttgtgagtga acaggaggac gaggaatgac atataaactt gtaatcgcgg
    16321 aaaaacccag cgtggcccgc agcattgcgg gcgtgatcgg ggccacggag aaacacgacg
    16381 gctatttgga ggggaacggc tatctggtga gctggtgcat cggacatctg gtgtcctttg
    16441 ccgacgccgg acgctatgac gagcgtttca aaaaatggcg ctatgaggat ttgcccattc
    16501 tcccggaaac atggcagtac atcgtccccg acgacaagaa acagcagttt gacgttctct
    16561 gttcgctgat gcagcgcccc gacgtgaccg gccttgtgtg cgccaccgac gccgggcgcg
    16621 agggggaatt gattttccgt ttcgtctacc agatggcggg atgccaaaag ccctttgagc
    16681 gcctttggat ttcctctatg gaggacagtg ctattaagga cggctttgcc cacctgaaac
    16741 cgggcggcga ctatgatccg ctgtatcaat cggccctgtg ccgggccaag gccgactggc
    16801 tgatcggcat taacgccacc cggctttttt ccgtcctgta ccacaagaac ctgactgtgg
    16861 gccgcgtcca gacgccgacc ttaaaaatgc tggtggacag ggacgccaag attaccgatt
    16921 tcaagaaaga gaaatatcac atcgtccata tcacggcggg cggcgcggac gcggtaagca
    16981 gccgcttttc cgacgctgcc gaggcaaaca ccgtcaaggc ggcttgtgca aaagcgcagg
    17041 ccgtttgcgt ttccgtgacg cgggagaaaa agacggaaca gccgcccaag ctctatgacc
    17101 ttaccacctt gcagcgggag gctaaccggc ttttcggcta taccgccaag cagacccttg
    17161 actatgccca ggcactgtat ctaaagaagc tgctgaccta tccgagaacg gatagtcaat
    17221 atcttaccga cgatatgctg cccgccgtgg aaagccttgt gtccggcctg tgggagctgg
    17281 tgccgtttgc caagggcctg aacctttccc cgcagtttga ccgcatcctg aacagcaaaa
    17341 aggtgtccga ccaccacgcc attatcccca ccgctgaatt tgtgaagcag ggctttggca
    17401 ctctggccga gagtgaaaaa aagctgctgt ccctgatctg ctgcaagctc ttatgtgccg
    17461 tggccgggcc gcatatctat gaggccgtca ccgccacatt tacctgtgcc gggcaggagt
    17521 ttaccgccaa gggcaagacc gtcctttccc ccggctggaa agagattgaa cgccggttcc
    17581 gttcttcctt aaagaccgac gccgacgagg acgccgaggc ggtgcgggag ctgccggagc
    17641 tttgcgaggg ccagaccttt gcagacgtgg ccgcctctgt caccgagcat ttcaccacgc
    17701 cgcccaagcc ctacaccgaa gatacgcttt tgtccgctat ggaacgggcc ggggccgagg
    17761 atatgccgga ggatgccgag cgcaagggat taggcacacc ggccacccgc gccgccattc
    17821 tggaaaagct ggtgcagatg ggctttgtcc agagaaaagg caagcagctc attcccacca
    17881 aggacggcat caatctggct gtggtgctgc cggaggcgct tacttctccc cagcttactg
    17941 ccgaatggga aaaccggctg accgagatcg ccaaggggca ggccgatcct gacgaattta
    18001 tggacggcat cgagacgcag gcgcgggagc tggtgcagac ctattcctgt atcagtgagg
    18061 aaaagcagaa attgtttcag gccgagcgtg ttcctatcgg gacgtgtccc cgctgtggtg
    18121 aggctgtcta tgagggcaag aaaaactact actgcggaaa ccgggcctgc cagttcgtca
    18181 tgtggaagaa tgaccgattt tttgaggaac gcaagaaagc gttcaccccg aagatcgccg
    18241 ctgcgctgct caaaaccggc aaagtcaagg taaagggcct ctattccgta aagaccggca
    18301 aaacctacga cgggacggtg cttttggctg ataccggggg caagtacgtc aactaccgca
    18361 ttgaacacag gagctaaagg acagtaacac agcaagcata gggagtgtgg ctacactccc
    18421 ggtaaaatcc cccggccgcg tccctgccgg gccggggatt tttgcttgtt ggggaagtcc
    18481 ccaaccccct attttttgaa acagaacaga gaaaggagtg accgcgtgaa cgaagtattt
    18541 tctatccaag tccataaccg gcagtttttg gaacagggca aacaaggcgt ctggctggat
    18601 ttgcccacca caaccgaaac gctgcaagcc gccctgcggg atgttggcat tactgccgac
    18661 aatccgcagg atttttttat caacgggtat tcctgcccgg aggacagaca ccttgccatt
    18721 ccctatgaca tggtgctggc cgccgacgtg gacgagctga atttccttgc cgcccggctg
    18781 ggccagcttg acgccgccga gatcgcagag ctgaacgccg ccctgcaaaa tccccgtggc
    18841 ggctttgaga atatcggcca gatcatcgac tacaccgaaa atgtggatta ctatgtgcat
    18901 cttcccgacg ttagggggga tggacagttg ggcgactact acctgaaccg ttccggcatg
    18961 gtggatatgc cggaggaatg gaaagccggg attgatacgg cgcagtttgg acgccacatt
    19021 gcccagcagg aacaaggcgt ttttacccag tacggctatc tggtgagaag cggcgacgaa
    19081 tggcagcgcg tccatgaggg ccagccggtg ccggaggaat accgggtgat gcactacccc
    19141 cagccggaag ctgaccggga ggaaccgcag gcccagcagc cggaggcatc cgaaagcccc
    19201 gacaaagcgc cgcccccggt tatcccgatc atgctggacg gcatgaacag caaagaacgc
    19261 atgaaagtga ttactgaccg tctggaaacc ggcgtacagg agctttttga aagtagccgc
    19321 tatatggctt acttatccgc tatgtccaag atgcacgatt acagtctgaa caatacgctg
    19381 ctgatcgcca tgcagggcgg ttcgattgtg gcgggctata acaggtggca ggatgaattt
    19441 gaccgccatg tgaagcgggg cgagaaaggc attaagatac tggccccggc cccgttcaag
    19501 gttaagcagc agatggagaa aaccgacccg gccacccagc agcccgtgat cggcgcggac
    19561 ggcaagcccg tgaccgaaga acaggaagtg acggttccgg cctttaaggt ggtgacagtc
    19621 tttgacatca gccagaccga gggcaaggat tttcccatgc cctatatcag tgaacttacc
    19681 ggcgacgtgc agcagtatca ggatttcttt gccgcgctgg aacggacatc accctatccc
    19741 ataagcattg agccgatttc agacggggcc aagggccgct gcttctacgc aaaacagcgc
    19801 attgccatca acgagggcat gagcgaattg cagaccctaa agaccgccat ccatgagatt
    19861 gcccatgcca agctccacgc cattgaccgg gaggcccccg ccgaggaaca ggcggcccgg
    19921 ccagaccgca gcacccgcga ggtacaggcc gaaagcgtgg cctataccgt ctgccagtat
    19981 tacgggctgg acacgtcgga ctattctttt ggctatgtgg ccgattggag cagcggcagg
    20041 gagttatccg agctgaaagc ctcccttgaa accatccggg ccacggccag cgaattgata
    20101 accgagatcg acggccattt tgcccagctt cagcaggagc gcgaggcccg gcaggaacag
    20161 gaggccgtca cggttgacgt taccccggag gcagcggccc cggcgcaggc cgaggaagaa
    20221 caggccccgg cccttgatcc ggcagccgag ccgcttgtga ctgtgctatg gagcgaaagc
    20281 ccccagctaa aggacggcca gcaaatgccg ttgcatgagg ccgacgcgct gtttgcccgt
    20341 ctggatgcag catatccggc agaggcaggc tatgacaaaa ccgcgttccg cattgactgt
    20401 atctttcagg gcgagccgga cagctacgag gggcggcagg attttggaga tagggacggt
    20461 tccctgatcg aacatatcca gagctaccac caattttacg cgcaggacga aaactggaaa
    20521 aagcatgtaa tcgctacaac cggcatagag ggctgggagc aggacaaggc ccatcgggat
    20581 atgctgttag gcgagtttgt cccctatatg aagctgcatt gcagccttgc ccaaatggaa
    20641 cagacggcgc agggccgctt acagtccggg gaaaccctga cgccggagga aacggcctat
    20701 ttgggggcgc ttctctctta tgtgcaggag tgccgcccca tgctcaatca gggccagtat
    20761 cagttgccgg agccgccgaa actggctgac ttcgaccaga gcttgcagga ctacaaagca
    20821 caggtacagg ccgagatcgc gcaggaggcc gccgcagccg gtatgaccgt ggaggaatac
    20881 gcggcggctg gctatgaagc accccaacag gacacctttt ccatctacca gcttcgaggc
    20941 ggggaggaaa cccgcgacta tcggtttgag ccatacgagc gtttacaggc cgcagggctg
    21001 gccgtggaca gtgccaacta tgaccttgtt tatacggcac cgctggataa aagcacgtct
    21061 ttggaggata tttaccgcac attcaacatc gaccacccgg cagattttag gggacacagc
    21121 ctttccgttt ccgacgtggt ggtgctgcac cagaatggac aggacaccgc ccactatgta
    21181 gacagcttcg gctatatgga agtgccggag tttttgcggg aaaatcccct gcgtaccgcc
    21241 gaactgtcta cggagcagaa cgaaaacatg attgacggca ttatcaacaa tacgccgccc
    21301 gaaccgcagc cggaggaacc cgaacagcta tcttttgagg atgtggcagt tgcttccggc
    21361 cagacacagg aggaaccccc ggaggctgcg cccccgcaaa cggctgtccg ctattatccc
    21421 atcaatgagg gagccgcccg ccgcgccaag gaagccatga gcttttctga ctaccggccc
    21481 ggcagcgcca cggcggaata ccggcactat gtcgatcagg ccgtggaaat tgcggagcgc
    21541 cagaaaaagc gtgtggagcc agagtatcac gaaaagatag acagcctcct tgacacctac
    21601 gcccgcaagc tggccgagaa catgaataag ggctatgaga ttaccgcccg cgtcccctct
    21661 gtcctgattg ccgggccgtc caatttcccg gtacgggcga aagaaaagca gaacgccgcc
    21721 agtgaccgca acatggagga atttcagtac attcagggct tgcttgacaa aatccgcagc
    21781 accggcatgg gtggtatcag cgccgacgat ccgcaggccg tttccaagct ggaaaagaaa
    21841 ctggaaaagc tggaagcgtc gcaggagttg atgaaggccg tcaatgccta ctaccgcaag
    21901 catgggacgc tggacggatg cccccatctg atcgaaagag gcattgaaaa cctgaaagcg
    21961 gatatggcgt cgggctggca ctatgagaaa aaaccgttcc agtcctggca gctctccaac
    22021 aataacgccg agatacgccg gttaaagggc cgcattgagg aattgacccg ccaaaaggag
    22081 gcggcctatg tgggatggga gtttgacggc ggcactgtgg agatcaaccg ggtggccaac
    22141 cgcctgcaaa tcttctttga ggggaagccg gatgctgctg tacgcgacga gctgaaaagc
    22201 aacggtttcc gctggtcgcc caaggccggg gcatggcagc ggcagttaaa cgacaccaca
    22261 atccgcgtcg ctgaccgtat caagtgcatc cagccccttt ccggcgaaaa gcccagcgcc
    22321 ttacagcttg cggcccgcag ggagaaagaa aagccctcta tccgggcgca gctcaacgcg
    22381 gccaagaccg aacaggccaa gcagccaccg gcgcgggaaa aatcaaaggg attggaggta
    22441 gagtaaatgc agaagtttga aaatgtggac gttctggccg cgctggaaca gatcatgcgg
    22501 cagaacaccg cgttttatca aagtgacttt ggcattgaca aagacattat caggcgggat
    22561 gccgccagcg atcaggccgc agacaagacc ctgctctgga tgtcccggcc ctccgggacg
    22621 tactgtttcc gggaacgtga tgttttcctg aaagacaccc gacagtacaa cacatggaaa
    22681 ttttacgggg agcagacccg tgacaagata ctggcctacg cggtggagct gaccggcaca
    22741 cagggcggca ctatccgggg caatctctat gagctggact atccgcagca tttccggcac
    22801 gtcattgaaa ccgcccagcc ggtgagtgtg aaccggctct tttatgagca tggcacccgt
    22861 gacatcccgg agagccagcg ttttgacgga agccctgacc gggtattggg aaactttttg
    22921 tactatgagg cccagcccca tgacccggct gtgctgcagg aggcgctacg gacggagcag
    22981 cacagccggg ggcgggccgt ccccggcgat ttcaaagtcc acgtcaccgc tttgcatgac
    23041 agccggattg aaaccgaggc ccggcgtatt gtggacagcc tgaaagatct gtccgcgcct
    23101 aacagcccca ataaaacgca tttcatggtg gagatctccc cgcactttgc ggcgattgct
    23161 tccaccaagg ataatgaccg gctctttgcc atgctgccct ataaatccct gtgttttacc
    23221 gggatgaaag gcaggcatgg cgtgtatgcc gtgattaacc gggacgagcg ccgggatgtg
    23281 agtattcgca ggccccggcc ctctatccgc aagcagctat ccgacagcaa acaggccgcc
    23341 agcccaaaaa aggcggcggc cagaaccaaa aagaatgaat tggaggtata aggaatgatg
    23401 cactttaccg tggaggaaga aaacctgatc tgtatgtacc acaatgcaga ccggcgcaga
    23461 acgataaaca ggctcaccgc cgtcatgccg gttatggatg gggatatgcg ggcgcaggcc
    23521 cagcagaccc tttccaagct ggaacgcatg acggatgccg actatgacgg ccagaagttc
    23581 cacttcacag acgaataacg aacagcagac gccgggcgcg gcggccatgt ggtcgcttgc
    23641 gtccggcgtc ttttcttttt gcctattcct acgcatttag aacccggtat tgtcggggat
    23701 aggatgaagt attcgcttgc ccctgcaaac atgcgggaga agccttgcag cgggcggttt
    23761 tcaatccctt aaatgcgtag gttgcagcta taattagacc cctgaaacag atatagccgc
    23821 gcagcgggtg tatctgtttc aggggtgtgc aggtgatagc cgcaaagcgg cgtaagaggg
    23881 tgcagccctc ttgccgtcta tctctgttcc agcgggaagc tcggcaatgc ttccagcagt
    23941 ttcagggaaa tgcgctgccg tatatcttcg tcaatgactt tcttcttttt gccgtttgcc
    24001 tgtctgatct ccaccgtgga aagctcgttg atgtagtcag cataatgggc caacactttt
    24061 tccgtggccc acctctcacc ggcaacggcg gctttgatcg tttcatagtc cagcagcttt
    24121 tcttgtccgt ccatcctgat acccccgtca gactgatttt ttctatgata ccatattcgg
    24181 aagcatggaa ccagagaaaa cggcgctttt ctgctggtaa attctacgca tttagaacag
    24241 cacttcggcg gggataggat aaaacaccca cataccccgc tgaccatgcc ggaaaagcct
    24301 tgaaatataa gggcttttac agctctaagt gcgtaggttt ccagtatctt ttccgctggc
    24361 gctcggcctc tttgcggcgg cgcatccgtt tggagcaggc cgcgcagtat ttggcccggt
    24421 tagacttcgg cgtgaacgtg gccccgcact cacagcagcg tttcacttcg tcccggtctt
    24481 tggtgatctc ggcatacagg gccgcatcca gcgggaggac agcggcctta aaccagcggc
    24541 acagaagcga ataggaaatg ctctgtacgc aaatacattc ttcgccgtcg tccagcaaca
    24601 ggcagttgcc gtcacaatag ttgcagcact catgcgtcag cttccgggcc ttgcgatatt
    24661 gagggtaatt cattcgtgga atactcatag ctcttgcgtc cattcctttc ccggcgtcat
    24721 acgcaaaatg ccgtccacat tctgcttgat gatgccgtat tcctgcatct gctttttcgc
    24781 ttcgccgtac ttctcataca gccgttcctt ttcctcggcc aatcgcttgt actcggcttt
    24841 cagggcgtac agatcgggga gctttttcac accctgtccc tttagggcct ttgccgcagc
    24901 ttcatacaaa atcaacgtgc tttcatgctc acgccggaat tttgccttat ccgctgcatt
    24961 gcggtattcc atagccacgg gccagagctg cttgtaggta gaaatattct ttatcagcac
    25021 cgccatatcc gcaagccggt gttccatagc tttgagggta gcggcggcct cgtcgctggc
    25081 ggcggtgatc tcggccactt tgctttccaa atccgggtag gtgtctatcc catgttcagt
    25141 caggaaattc aaagtctttg cggcctgctt caaattgtgg agcttcgccc acctctcata
    25201 gcctgccgac tgctgggcct taatgttgtt ttccagatca atccgcaaag aaatcccctt
    25261 gcgctctttg ggcgctctgg tgataacgcg gcctttgata cgctctttga tggcttcctc
    25321 ggtgtaggct tcccccaatg tcttgcagcg ggtaaagcgt tcctgtccgg gagcgcggaa
    25381 agaaataaac tttcccggct tgatctcata gccctgcgcc tgcatgagcc gcaggaaatc
    25441 atcaaaatct tttgcctgcg ggatagcggc gtcaatggct gctttgagct tcgctttcca
    25501 gctcgtccct ttccgctggg cgtcccactc ggcatagctc ttgcccttac tctggccggg
    25561 cttcaccacg gacaatccgt tttccttgca cagcctgtcg ctggtgcgcc ggatataggc
    25621 atagctctgt ttgttggaaa tgtacttgcg ctgatttacc atatccacgg cacagaaaat
    25681 aatgtgattg tggacgtggc ccttatcaat atgggtagtc agcacatagg gatatttccc
    25741 ttgcagcact tcctcggcaa gctgcttccc gatctcatgg gcctgttccg gcgtggcttc
    25801 gccgggggca aaggattgta tcaggtggtg gcccagatta ttgccctttt ggtatgcctg
    25861 cgccagcagc atttcaaatt caatgtccgc tgtttcataa gagcaggcaa aggaggccac
    25921 cagcagcttg ccgtcagttt tgtccgggtt ctcgatgtag tcaagggctt ttttcagcgt
    25981 tgacttgata ggatgtatct ttgtaactgc catatctgcg ccagcgcccc ctttatatcc
    26041 tcgatgtcct gtgcgtacac cggccccata ccgttcagcc tctttgcaat ctgattgacg
    26101 ttgacgccga tcttctgtat ctcggcggtc tgcgcccgga tgtcgctggt gtccatgttg
    26161 acgatatagc cgtcaatgag catcttccgg gcgtaggctg aaaagttctt cgtatgcagc
    26221 agcgccattt tctgttcaat catagcccgt tcctccggcg tcacagggac gcgcagcacg
    26281 atttttcgct ttctgtttgc catgcttcac cgtcctttcc attcaggggt ttggggattt
    26341 ccccaacaag caaaacggac gcggcccggc agggacgggg caggccgttt ttccgggagt
    26401 ggctacactc cctatgcttg ctacgttact gtttctccac taacaagacg tttccaaagc
    26461 cccaaactac ccgcaaaata gccctctgga aagaaaaaag tgcaaaaaaa tagaagctac
    26521 gctgtgcagc tcccgctaaa agtaaaacag aggatgccag ttacacatcc tccgtttcat
    26581 tcttcttcgg cttttcaatt agtatggcgc tgtcaatcgc gccctcgatg atcggcaggt
    26641 attcttcggg gcagagtttc agcttgtggc tgaccctttg ccgcagttcg ctttcctccc
    26701 gcatgatctc cgggttaaag tagcgttcca caggaagccc gcaggcttta ataagctgta
    26761 tgacaaccgg cagactggga atggcccgtc gttttcgatg ttggcaagat agcgccagtc
    26821 aatatttatt ttctctgcca ttgctttgcg cgaaacgcgc tttgcttgcc gggccgcttt
    26881 cacatccgcg ccgaaagttt caaagccggg acaatcttca atattcgcca tatcgcacct
    26941 cccacttaca ttgtatattt catactctgc ccgtggaatg ttggtatatg cacctttctt
    27001 aaagtttata tttcacattt tgtttctttt attcttcgag caaaagaatt ataatgtacc
    27061 ctgtggaggt gtactatgga ctacatgacg ttgaaagagg caggcgagaa atggggtgtg
    27121 cccccacgat ggataaacta ctattgtgct gcgggacgca tccccggcgc tgtaaagatg
    27181 gcgacgatct ggctcattcc caaaactgcg gaaaagccga ttgacaggcg tacaaagaaa
    27241 ggaaaggcgg ttactgaata gtataatgaa accggcgcat tttggatatg gttttgaaga
    27301 gagagaaagc atggtatttt gtcacggaaa aactataaga tgatagatgg caggctgctc
    27361 cagaccgata aaaagtattc tcatctgaaa cagaaagaaa agatttacac atggatgtat
    27421 gaagaagcga aactttatca tgacagaaat ggaaaatgcc cgaaacaaag acgaggaagc
    27481 tgctgctgta tcagccgtat atggtagaat tgaaaaggcc ggcatctgga ttctttatgg
    27541 tgaagtctcc agacattgga taactgctgg tctaatgcgc ctttgagtat ggggtgattg
    27601 attttaatac cggggaggta cggctttttg aggaaaatat tctgggattt acatttggcg
    27661 attattacat ttcctgtaac tgcaaggaca cggatgatga agatatgagg aatatagact
    27721 tgctgatttt ctactgtctt gaacggtatt aggactgaat ctgctgcgcg gagtgcggca
    27781 agagcgaccg gagggagtac acacaggccc tgcctgtgtg aaaagccata ccgcaaggtg
    27841 cattcgcaaa aaagaggccg cgcattttgc tgaggcttgg ggtgtcccca acaagcaaaa
    27901 cgagaacgcc gcaggcgggc aagtggtgga tcagaatatc cgtaaaggat attctgatcc
    27961 attgcttgcc agtattatcg ggatgttttg acaaccgctg taatcgaaac atcccaaaca
    28021 ttaagaaggt gttaattatt attatcttga tttaattcgt ttaaaccaat aatatagata
    28081 catacaccat gaaaagaagc gagtatccca atgacggatg attaaaatcc gaaaagaaat
    28141 cgctttgaaa ctacagggaa actacagact gttatgttat cttcttaaaa tggagggatt
    28201 tttatgtcga tacgaattct acttgtcgag gatgatgatc atatctgtaa tacagtaagg
    28261 gcgtttctgg ctgaggcagg atatcaggtg gatgcctgca cagatggaaa tgaggcatac
    28321 accaagtttt acgaaaacac ttatcaactg gttattcttg atattatgct gcccggtatg
    28381 aacgggcatg aacttttgcg tgaatttcgt gcgaaaaatg atactcccat tctgatgatg
    28441 acagccctgt cggatgacga aaaccaaatc cgggcgtttg atgcagaggc agacgactat
    28501 gtaacaaagc cattcaagat gcagatttta ctaaagcggg tggaagccct gctgcggcgc
    28561 agcggtgcgc tggcaaagga aatccgtgtc ggcaggctga cacttctgcc ggaggatttc
    28621 acggtacttt gtgacggtac agagctgccc ctgacacgaa aagaatttga aatccttttg
    28681 ctgctggtgc agaacaaagg cagaacctta acgcatgaaa tcattttgtc acgtatatgg
    28741 ggatatgact ttgagggtga tggcagcaca gtccacactc atatcaaaaa tttgcgggcc
    28801 aagctgccgg aaaatatcat caaaaccatt cgcggtgtag gataccgatt ggaggaatca
    28861 taataatgga aagaaaaggg attttcatta aggttttttc ctatacgatc attgtcctgc
    28921 tactgcttgt cggtgtaaca gcaacactgt ttgcacagca atttgtgtct tatttcagag
    28981 tgatggaatt acagcaaaca gtaaaatcct atcagccatt ggtggaactg attcagaata
    29041 gcgataggct tgatattcaa gaggtggcag ggctgtttca ctacaataac caatcctttg
    29101 agttttatat tgaagataaa gagggaagcg tactctatgc cacaccaaat gccaatacat
    29161 caaatagttt tagacccaac tttctttatg tggtacatag agatgataat atttcgattg
    29221 ttgctcaaag caaggcaggt gtgggattgc tttatcaagg gctgacaatt cggggaattg
    29281 ttatgattgc gataatggtt gtattcagcc ttttatgcgc gtatatcttt gcgcggcaaa
    29341 tgacaacgcc gatcaaagcc ttagcggaca gtgcgaataa aatggcaaac ctgaaagatg
    29401 taccgccgcc gctggagcga aaggatgagc ttggcgcact ggctcatgat atgcattcca
    29461 tgtatgtcag gctgaaagaa accatcgcaa ggctggagga tgaaatcgca agggaacatg
    29521 agttggagga aacacagcga tatttctttg cggcagcttc tcatgagcta aaaacgccca
    29581 tcgcggctac aagcgttctg ttggagggaa tgcttgaaaa tatcggtgac tacaaagatc
    29641 attctaagta tctgcgcgaa tgcatcaaaa tgatggatag gcagggcaaa atcatttccg
    29701 aaatactgga gcttgtcagc ctgaatgatg ggagaatcgt acccatagct gaaccgttgg
    29761 acatagggcg cacggttgcc gagttgctgc ccgattttca aaccttggca gaggcaaaca
    29821 accagcggtt cgtcacagat attccagccg ggcaaattgt cctgtccgat ccgaggctgc
    29881 tccaaaaggc actatccaat gtcatattga atgcagttca gaacacgccg cagggaggcg
    29941 aggtacggat atggagtgag cctggtgctg aaaaatgccg cctttttgtt ttgaacatgg
    30001 gcgttcacat tgatgatact gcgcttccaa ggctgttcac cccattctat cgcattgatc
    30061 aggcgcgaag cagaaaaagt gggcgaagca gaaaaagtgg gcgaagcggt ttaggacttg
    30121 ccatcgtaca aaaaacgctg gatgccatga gcctccagta tgcgctggaa aacacctcgg
    30181 atggcgtttt gttctggctg gatttaccgc tcacatcaac attgtaaata tttaaaactt
    30241 aaatgatttt gggctctttg tcaaatagga ctgatagagt gagataagaa catctaaggt
    30301 agaattcctt ttctacttta gatgtttttt gattcatagg taatcagatt atttagtaag
    30361 aaaattctgg tcttcatttt ccgaaagctt cgaaagccat aagcgactcg tttcaatgct
    30421 ttgatgtggg tatgcagatt ttctattttg gcatttgaat aaggcaattc gagggctaaa
    30481 cgaatgccgg attcatagtt tataaaagct ttttttatag aatgcagttc ttttggaacg
    30541 gaattgggca tcgttcttac aagtttaaag aaagtgtccg cctctttgtc gtgaaacgct
    30601 tgaagaattt cttgatagta aaaataggcg attcgtaatt cgtcagagat cgaaagcaga
    30661 cgatccacca cttcactttc ggtgagatac gcccaaccaa aattgcgcca tttggtccat
    30721 ttgtcataaa caagcttgtc ctgtcgtttg atcagaagcc gagacaacgc ctttaattgt
    30781 cgataatatt tggcttgtgt tggatcgttt cgatcaaagc ttttcatgat tcgtacgcga
    30841 atatcctcaa atttacgaat gagatgtttg acaatgtgaa aacgatccac aacgagtttt
    30901 gcctttggaa aacattcctt tatcagagag gcataagaaa cattcatgtc cgtcacgatg
    30961 acctttacct tcaatcgtgc gcgtcgttca aattgcataa aataagaaac gagagccttt
    31021 ttcttccgtg aaggaagaat atccagtaat tttccagtat cgccatccat acaagaaaag
    31081 gagtagggac cgacttgatt tttcagtgaa cgaaattcat ccattaataa acaacgcggt
    31141 aaccaatttc tttttacttt tgtcatgggg atcagagaag cgagtgtccg agaaacggtc
    31201 gaccaagaaa cgccgcaatg cttagcaatt gtcgtcattg cttgtttttc agttagctct
    31261 tctaaaattt tatagcgcac ttgtttagcg ataaagcagt ttctatcgac aatgtaggta
    31321 ttcgccgtaa aataggtgtg gcagccacga cagtggtagc gttgtttcgc taaagcaaga
    31381 taagtcagtt ggttcgcaca tttattaagt tgaatgagcg attttttctt tccgttctta
    31441 acgatcatgc cttcatgatt catctgttta cacaaaggac agcgacgaat ttctttactt
    31501 aacgtcgcag aaacaacaag actcttgata ttcttaatgc tcttcgattc cacatttgtg
    31561 atgaaaatgt ttttatcttt gattccaagt agtagtttga tatgatgaag atcaggcata
    31621 cagaacgctc ctttgattgt gttgtggtga ttcaattcta acggagcttc tgtatgtttt
    31681 gttttttcat gctcaaaagg gaccgataga atgattttct atcagtccta gaaattatag
    31741 agccgatttt gaccgacagg tataaccctg ccggtctttt tttgctgcta caggaaaact
    31801 acagactggc tacagggaaa gtacagatgc gcttgccata ataacaatcg taccagccac
    31861 aaatcgtagt tttattgcaa aggaggcatt cgatcaaatg gaaaaaagca actatcattc
    31921 caatgcggat catcacaaac ggcatatgaa acaatccgtg gaaaagcggg cttttctatg
    31981 tgcgttcatt atttcgttca cagtctgcac gctgtttttg gggtggagac tggcttccgt
    32041 attggaggca acacagatac cgcccatccc tgcaactcat acaggcagca gcactgacgt
    32101 agtggagaat ttggaggaaa acgctcttgc caccgccaaa gaacagggag atgaacagga
    32161 atggagcctg attttagtga acaggcagaa ccccatcccc gcacagtacg atgtggagct
    32221 tgagcaacta tcaaatggtg agcggataga tattcggatt tctccctatc ttcaagattt
    32281 gtttgatgcc gcaagaactg atggagttta cccgattgtc gcatccggat accgaacaac
    32341 agaaaaacag caagaaatta tggatgaaaa aattgccgaa tataaggcga aaggctacac
    32401 ctctgcacag gctaaagcgg aagcagaaac ttgggtggcc gtgccgggaa cgagcgagca
    32461 tcagcttggt cttgctgtgg atatcaatgc ggacggaatt cattcaacag gcaacgaggt
    32521 ttatagatgg ctggatgaaa acagctatcg ttttggtttt attcgtcgct acccaccaga
    32581 caagacagag ataaccggtg tgagcaacga gccgtggcat taccgatatg ttggcatcga
    32641 agctgccaca gagatgtaca accaaggggt ttgccttgag gaatatttaa aaccagaaaa
    32701 atgagaaaag gatgttatgt tatggacaga aaaagattga cacagcgttt cccgttcctg
    32761 cttccaatga gacgggcgca gagaaaaatg tgcttttatg cgggaatgag atttgacggc
    32821 tgtcgctatg cgcagacgat aggggaaaaa tcgctttccc atttgctctt tgaaacggat
    32881 tgcgcattat acaaccacaa taccggattt gacatgatat accaggaaaa caaggtgttc
    32941 aacttaaagc tggcagcaaa gaccttaaac ggcttattga taagaccggg ggaaaccttt
    33001 tctttctggt tgttcctgca tacgccattg acaattatcc agcgcagagg tcacgaagta
    33061 aaggagtttc cagagccaaa cagtgacgag attaaagggg tggatgcaac catttcagag
    33121 ggctggattg atttaaaagt gcgaaacgat accgactgca cctaccaaat atgggtgacc
    33181 ttagatgatg agaaaatcat cggtcaggtg ttcgccgaca aagagcccca agcattatac
    33241 aaaattacaa atggcagtat ccagtatgtc cgtgaaagtg gcgggattta tgaatatgcc
    33301 caggttaaac ggatgcaagt tgccttaggt accggggaaa taatagattg caagctgctt
    33361 tatacaaaca aatgcaaaat ctgttatccc ctcccggaaa gtgtggatat tcaggaggag
    33421 aaccaatgag aaaaagtgtg ggcattactg tttttggatg cgaacaggat gaggcaaatg
    33481 ctttccgcgc tttatcgccg gattttcata ttatccctac gctgattagc gatgcgatat
    33541 cggcagacaa cgcaaaattg gccgctggca atcaatgcgt tagcgtaagc cataagtccg
    33601 aggtttccga ggcgacaatt cttgcgctga gaaaggtcgg ggtaaaatac atttctaccc
    33661 gcagcatcgg ctgcgatcac attgatacga ctgccgccga gagaatggga atctcggttg
    33721 gcacggttgc gtattcgccg gacagcgttg cggattatgc tttgatgctg atgctgatgg
    33781 ccatacgggg tgcaaaaccc accatgcacg ccgtggcgca acaagatttc agattggatc
    33841 gtatccgggg gaaagaactg ggggatatga ctgtgggagt tattggaacc ggccatatcg
    33901 ggcaagcggt cgtcaaaagg ctgcggggat ttggatgcca tgtgctggcc tatgataaca
    33961 gccgaaaaat ggatgcagat tatgtccagc ttgatgagct tctaaaaaac agcgatattg
    34021 ttacgctcca tgtgccgctt tgtgcggata cccgccatct gatcggtcag aagcaaattg
    34081 gagagatgaa gcaaggcgca tttttaatca acaccgggcg cggagcgctt gtcgataccg
    34141 gggcgctggt ggaggcgttg gaaagcggaa agctgggtgg tgcggcactg gatgtgttgg
    34201 agggcgagga tcagtttgtt tataccgatt gctcgcagaa agtgcttgac catccctttt
    34261 tgtcgcagct tttaaggatg ccgaatgtga tcatcacacc ccatacggcg tactacactg
    34321 agcgtgtgct gcaggatact acagaaaaaa caatcaggaa ttgtctcaat tttgaaagga
    34381 gtttacagca tgaatagaat aaaagtcgca atcatcttcg gcggttgctc ggaggaacat
    34441 gatgtgtcgg taaaagccgc aatagaaatt gctgcgaaca ttgatacgga aaaattcgat
    34501 ccgcactaca tcggaattac aaaaaacggt gtatggaagc tatgcaagaa gccatgtacg
    34561 gaatgggaag ccgacagtct ccccgccata ctctccccgg ataggaaaac gcatgggctg
    34621 cttgtcatga aagaaagcga atacgaaaca cggcgtattg atgtggcttt cccggttttg
    34681 catggcaaat gcggggagga tggtgcgata caggggctgt ttgtattgtc tggtatcccc
    34741 tatgtgggct gtgatattca aagctccgca gcttgcatgg acaaatcact ggcctacatt
    34801 cttacaaaaa atgcgggcat cgccgttccc gaatttcaaa tgattgataa aggtgacaag
    34861 ccggaggcgg gtgcgcttac ctaccctgtc tttgtgaagc cggcacggtc aggttcgtcc
    34921 tttggcgtaa ccaaagtaaa cggtacggaa gaacttaacg ctgcgataga agcggcagga
    34981 caatatgatg gaaaaatctt aattgagcaa gcgatttcgg gctgtgaggt cgggtgtgcg
    35041 gtcatgggga acgaggatga tttgattgtc ggcgaagtgg atcaaatccg gctgagccac
    35101 ggtatcttcc gcatccatca ggaaaacgag ccggaaaaag gctcagaaaa tgcgatgatt
    35161 acagttcccg cagacattcc ggtcgaggaa cgaaatcggg tgcaggaaac ggcaaagaaa
    35221 gtatatcggg tgcttggatg cagagggctt gcccgtgttg atcttttttt gcaggaggat
    35281 ggcggcatcg ttctaaatga ggtcaatacc ctgcccggtt ttacatcgta cagccgctac
    35341 ccacgtatga tggccgccgc aggaatcacg cttcctgcac tgattgacag cctgattaca
    35401 ttggcgttaa agaggtgata agtatggaaa atggtttttt gtttttagat gaaatgttgc
    35461 atggcgtccg ttgggatgcc aagtacgcca catgggataa cttcacagga aaaccggtgg
    35521 atgggtatga ggtgaatcgc atcatcggca caaaggccgt ggcgtttgct ctgcgcgagg
    35581 cacaaatcca tgcggctgcg cttggctatg gcttgctttt atgggatgga tatcggccaa
    35641 gaactgcggt ggactgcttc ctgcgttggg cagcgcaacc ggaggacaat ctcacaaaag
    35701 aaaaatttta ccccaatata gagcgagccg agttgattac aaagggttat gtggcctcac
    35761 aatccagcca tagccgtgga agcgcaattg atcttacgct ctaccacctg gatacagggg
    35821 aacttgtttc aatgggaagt aacttcgatt ttatggacga acggtcgcat catacagcaa
    35881 aagggatagg ggatgcagag gcacaaaatc gaagatgctt gcgtaaaatc atggaaagca
    35941 gcggatttca gtcttatcgc tttgaatggt ggcactataa gttgattgat gagccatacc
    36001 ccgataccta ttttaatttt gccgtttcat aatgaaagta ttggttttgt atcagatttt
    36061 ggatttgata aaatctatgc tggtcatgga caatctttta ctggaaagtg gttaaagcat
    36121 cttttgtaat acattgcaaa ttatagtatt caatctgccc agcggcagaa aagaaaaaaa
    36181 ccgctgttgg gcagaccttt cccacgccca ttttgtattt tgctggcggc ggttttgaga
    36241 aatcaaggcc gccgttcttt tctggcagca aaaggtgtgg cggcccatag gaggatgccg
    36301 ctatgctgtt ttgctattgc catgctctaa tccacttcca ccactcaaaa aaagccttgc
    36361 ccctccatga actgaacccc aaaagttgaa ctatttaatg gactgt
//
LOCUS       DAZAOD010000266        13954 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.069, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000266 DAZAOD010000000
VERSION     DAZAOD010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.069"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..343
                     /locus_tag="ACHDPO_003062"
     CDS             <1..343
                     /locus_tag="ACHDPO_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFN3370589.1"
                     /translation="LKKTGESRGILELLREGQQGVTLRTFESMYFQKKLVTDNQAIAH
                     YHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKRFITNDSTIYEQ
                     YEYDLSSVENK"
     gene            complement(493..1434)
                     /locus_tag="ACHDPO_003063"
     CDS             complement(493..1434)
                     /locus_tag="ACHDPO_003063"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFN3370590.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1560..2681
                     /locus_tag="ACHDPO_003064"
     CDS             1560..2681
                     /locus_tag="ACHDPO_003064"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFN3370591.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2939..4441
                     /gene="eat(A)"
                     /locus_tag="ACHDPO_003065"
     CDS             2939..4441
                     /gene="eat(A)"
                     /locus_tag="ACHDPO_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFN3370592.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4508..5035
                     /locus_tag="ACHDPO_003066"
     CDS             4508..5035
                     /locus_tag="ACHDPO_003066"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFN3370593.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            5246..6307
                     /locus_tag="ACHDPO_003067"
     CDS             5246..6307
                     /locus_tag="ACHDPO_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFN3370594.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6310..7206
                     /gene="murQ"
                     /locus_tag="ACHDPO_003068"
     CDS             6310..7206
                     /gene="murQ"
                     /locus_tag="ACHDPO_003068"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFN3370595.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7220..9202
                     /locus_tag="ACHDPO_003069"
     CDS             7220..9202
                     /locus_tag="ACHDPO_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFN3370596.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9267..9713)
                     /gene="nrdI"
                     /locus_tag="ACHDPO_003070"
     CDS             complement(9267..9713)
                     /gene="nrdI"
                     /locus_tag="ACHDPO_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFN3370597.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            9924..11348
                     /locus_tag="ACHDPO_003071"
     CDS             9924..11348
                     /locus_tag="ACHDPO_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFN3370598.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11529..12302)
                     /locus_tag="ACHDPO_003072"
     CDS             complement(11529..12302)
                     /locus_tag="ACHDPO_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFN3370599.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12299..13204)
                     /locus_tag="ACHDPO_003073"
     CDS             complement(12299..13204)
                     /locus_tag="ACHDPO_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFN3370600.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13358..13678)
                     /locus_tag="ACHDPO_003074"
     CDS             complement(13358..13678)
                     /locus_tag="ACHDPO_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFN3370601.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         4440 a         2502 c         2965 g         4047 t
ORIGIN      
        1 cctgaaaaaa acaggggaat cgcgcgggat tctggaactg ttgcgggagg gtcagcaagg
       61 agtgactttg cggacatttg aatccatgta ttttcaaaag aaactagtga cggataatca
      121 agcgattgct cattatcatt tttatcgtcc tgaaaatatt tttttgcttc gagaacgtga
      181 tttagatgaa ttaccggaat ttctgcatac accatttaag ccaatcctat cagagctatt
      241 ggaattttat gatgcagaaa attgggcaaa acgatttatc actaacgatt ccactattta
      301 tgagcaatac gaatatgacc tctcctctgt tgaaaacaaa taaaaaacct acattttgaa
      361 gagattatgt actgaaacaa acaagcacaa ttcttatggc atcatgagag ttgtgttttc
      421 tttttgatct tttattgggc ttaaaaaaag agaaccagct gctgattcag ctgattctca
      481 tcagagagcc ttttattctg cgccaaggat tccttctttt gcatggacta attgggtcaa
      541 aaaggcacaa tatggtgtag caatatcata tttttgtcct tttcgccaaa tggcaccatt
      601 gatgtagtcg atttcagtca aacgatggtt tttgatcagg tcttggtaca tagatgggta
      661 atgcaacccg atgttgtcag gatcataagt agaagcaata tgttggtaca cttcttcttg
      721 atctagtatg attccttctt ttgctgcgat agaagcaaat tcagatacga ttgttcgaac
      781 catgctctct gccgcttttt gcgcgcctag ttcagcaata ttacaatcca aaatcgtgca
      841 taaaccattc aatgttccat ttacacaagc ttttcgccaa atggaataac gaacgttatg
      901 gctatagatc ggatttaaat ttgcttcttg aaagacttct acaacttttt ttgtaaatgc
      961 ttcgccttct ggttccaagt tctctagttc gatttctcca tcacctaaca atgtgacttt
     1021 tccgggacca gctagaccag ctgtccacat cgtgatccca aataagatat ttttctttgg
     1081 cacatatttt tccagtacat cttcatgacc taatccattt agtaaacaca aaacataagt
     1141 attgtcagta ataatggatt ggatcgaaca aaacatatca tctaattgat tggcttttgt
     1201 taatgctacg atcaagtcca cgtgttcgtt gctttcgatg atttcttctg gtgaatagat
     1261 tggcagtttt gcgaccactt ctttaccgtt aaagtcagca atcaacccat ttgtacgaat
     1321 ggcttcaatg tgagcaggcc aacgatcgat caagaggacc tcatttccgc tttgatgtag
     1381 catcaatccg attcggctgc ccattgctcc ggccccagct attgcgattt tcatgttttt
     1441 tctctccttt attcaatgag ttccctttta gtatatagaa aaatggaaga aaatagcatt
     1501 gttttgtttg aaaaaaatga aaaaaagtgt cttacttaag aagaaagtga gggatacaga
     1561 tggatatttt ggcggcaatt gattcattta aaggaagtgc ttcttcattt gaactaaatc
     1621 aggcagttct aaatggctgg gaagatcgta aaggaagaaa aatcaatgtg ccgattgcag
     1681 atggcggaga aaatactgca gaagcaatct attacgcgct caggggaaca tggcgtacca
     1741 ttgatgggat ggatctctta ttccgtcagc gaaaaatcag ctatttattg acaacttggc
     1801 aaggaaaaaa caccgcagtc atcgaatctg cacaagcatt ggggttagat ctacttgata
     1861 aaccaacgga tcaaactatc cgacttgctt ccagttatgc cttaggagaa cttattaaag
     1921 atgcactgct tcaagaagta gaacaaatta ttgtcacttt aggaggaagc gggtgtagcg
     1981 atggtggtct aggattactc caatccttgg gtgcttcttt agaagggtac acagaaggaa
     2041 atcctttatt atctactaaa aaacttcatt ttgatcgaag aaacgttctt gtttctaaag
     2101 taaaattgat tatcgctgca gatgttacca atccatatac aggtcaacaa ggagctgctt
     2161 ggcaatttgg aagacaaaaa ggaggaatag atacgacgct agctttctta gataaacaag
     2221 caggaaagat tgctcagcaa ataaaagatt tctgggaggt ggatttagat gatattccag
     2281 gaagtggagc agcaggcggt attggtggag cccttttttt gttgggagcg aagatggttt
     2341 ctggtttcga tttagtcagc caaatcactg gattggaaaa aaagatcgaa caagcagatg
     2401 tcatcattac aggagaaggg cggatcgatc agcaaacgat ccacggaaaa gttccatacg
     2461 gtgtagcagt gcttgcaaaa aaatatcgaa aaccaataat cgctatttgc ggaagtagag
     2521 accaagagct agaaggactt tctgattttc tcccaattgt cttaagtatt catttgggtc
     2581 caataggttt agaagaagca atggaacaca ggcaaacatt agaaaaaaca aaaatcttag
     2641 gacagacact tagcagattt ttcaccatcc tcccgaagta gttgacaaaa tcattttctt
     2701 tatgctatcg taatttcaaa tataggacaa agtgagggat ccgtgcattg aaaaattaag
     2761 tcgattgatg aaagctgcat tcagactgta ccttgtggag acaaggaagc agtgtgcaga
     2821 ttttcgggat tggcttggtt ttttcgatgt atgggtcttt ttgtgtgtat ccaacccttg
     2881 catcctcttt agccagttct gaaaatagga ctggtctttt tttacgaggt gatggaaaat
     2941 gtctaaaatc gaaataaaaa atctgacatt cggctacgac agccaaggca cattattatt
     3001 tgaacaagca aatctaaatt ttgacacaca atggaaacta ggacttatcg gacgaaacgg
     3061 tcgaggaaag acaactttac tgaatattct acaaaacaaa ctaccttatc aagggcaagt
     3121 aatccatcag caagaatttg cctatttccc gcaacagaca aaagataaag aacgtttaac
     3181 ctattacgtg ttaaatgata ttacggattt tgagatatgg gaaatcgaaa gagagctcca
     3241 attgatgcaa acagatcctg aaatcttatg gagagaattc agcacactat cggggggaga
     3301 gaagacaaaa gtcctactgg cacttttatt tgtggatgac actcatttcc cgttaatcga
     3361 tgaaccaacg aatcatttgg atatctctgg tagaaaacaa gtagcggctt atttgaaaaa
     3421 gaaaaaacaa ggcttcatcg tggtcagcca tgaccgggga tttatcgatg aagtagtgga
     3481 ccatgtttta gcaatcgaaa aaagtcaact ggaactttat caagggaatt tctctatcta
     3541 tgaagaacag aaaaaacttc gtgatgaatt tgaaatggct caaaatgaaa aattgaaaaa
     3601 agaagtcagt aggctaaaga aaacagcagc tgaaaaagcc gaatggtctc gttcccgaga
     3661 aggagataaa acaaagaaac aagtcggatt catcgatact gaatctagac gagtgaataa
     3721 aggagcagtg ggtgctgatg ctgcacggac gatgaaacga tccaaagcaa tcgtgaatcg
     3781 gatggagacc cagatcagcg agaaagaaaa actattaaaa gatatcgaat atatcgattc
     3841 tttgacgatg aatagccaag cgtctcacca taagcgactt ttaagcgtag aagatcttca
     3901 attagggtat gaaaatctgt tattcgagcc aattcatttt acaatcgagc ctcatcagcg
     3961 ggtggcgatt tcaggtccta acggtgcagg aaagtcatcc attatccatt atcttctggg
     4021 ggcattcaac ggcaaggtta taggagaaaa ataccagcca aaacatctga gcattagtta
     4081 tgcaagccaa aattatgaag acaatcgagg aacgttggcg gaatttgcag agaaaaacca
     4141 agtagactac caagcatttt tgaacaacct ccgaaagctt gggatggaaa gagatgtttt
     4201 tcataacaag atcgagcaga tgagtatggg ccaacggaaa aaagtggaat tggctaaatc
     4261 tttatcacag ccagctgaac tatatacatg ggatgaacca ttgaattatt tggatgtctt
     4321 caatcaagaa caattagaac aactgatctt gaacgtgaaa cctgccatgt tactagtgga
     4381 acatgatcaa accttcctgg ataaagtatc tactgagatt atttctcttg agagaatcta
     4441 acccttgtaa tctcaagaac aacaaggtat ggttaagggg aactttgcca acgaaggaga
     4501 gaatcacatg ctttatgtaa cgagacacgg agaaacaact tggaacgcac aaggattagt
     4561 ttgcggacgg gcagatgtgc cgctgactga aaaaggacag atgcaggcac agaaactagc
     4621 agaaaaggta gtagatttgc ctgttccaat cacgaaaatc atccattccc ctcttcaacg
     4681 agcaagagat acagcacaag cagttgctga tcgtctcagc ttgccgctga ccgttgatga
     4741 acgattggta gaaatggatt ttggggatta tgatggactg ccaagcaaag atgagaactt
     4801 tcaaaaagca cgtttagcgt tcgctgtacg attcccaaat ggggagtcag tcttagatgt
     4861 gtatgcacgg atcgttcctt tattgaaaga atgcatcgaa gacgaagaaa atgtctatct
     4921 gttagtttgc cataatgcct tgataagagt gatcaatgct tattttcatc cgatgcctaa
     4981 tgaggggttc tttacattca tggtagataa tacagaattg gtttcttatg agtaattatg
     5041 tttttgtgtt atttaaataa aatatttcaa ggcactgctt ttgcttagca gtgccttttt
     5101 taggttatga caattctttt gataatataa actcaacctt tagaaatgaa atttaattat
     5161 tttaataaaa gtattgaaat tttgtttctt tagatatata ctctagtcat agaaatgaag
     5221 acggatacag aaaaagaggg ataatatgtt tggcttttca atatttatga acgattcttt
     5281 gtcagaagag aagaaacagt atatccgcca aatggcatcc aatggctttg tcggtatttt
     5341 cacttccatg catataccag aagatgatgt ttcggcatat caaaagcgat tgatcgaact
     5401 aggaagcgaa gcgaaaaaga ataaactaga attgatggtc gatatttcag gagaggcatt
     5461 ggaacgagcg ggtttttcat tagaagatct aacgcctttg aaagcaattg gtgtaacagg
     5521 tttaagaatg gattatcata tttccaatca gcagattgcc gactggtcac atcaattgaa
     5581 aatcagtttg aatgctagca cgatcacgcc taaagatatc gatgaattga aagaagcaga
     5641 agctgatttc tcacagattg aagcttggca taattattat ccacgtcccg aaacagggct
     5701 ggacaaagaa tggtatcaga aaaaaaatca atggctcaaa attcaaggtc tccttgtcca
     5761 aggttttgta ccaggagata cagagttgag aggcccacta tatcaaggat tgccaacttt
     5821 ggaagaacat cgagggatcc atcctcttgc aggcgctcta gatctattag caagtaacac
     5881 ggatattgtt tacatcggag atgcaggtct gtcagaaaac gttcaggagc aatttgcttc
     5941 tttccaaaaa gaacagacag tcttgctcca tacggaacct gtagatgaag aattttacga
     6001 atatatatta gggaagcata cgaatcggca agacgatgca agagatgtca tacgaagcgt
     6061 agatgcacgt tttcgagaga ttccgcctat cccagcaaga aatacagcta cgcgtatgaa
     6121 agggtctatt actttagata acgaaaagta tttgcgctat atgggtgaga tccaattaac
     6181 caaatatgat ttgccagcgg atgaaaaagt gaatgtagta gctaaagtta tcaaagaaga
     6241 gctaccattg atcaaccaaa tcaaagctgg tatgaactat caatttataa gaaaagaagg
     6301 aagataaaaa tgagcaaaat caatttagag aacctaacaa cggaacgcag aaaccaagaa
     6361 acttttggat tagatgagat gagtatttct caagccgttc aactaatgaa caaagaagat
     6421 cagaaagtgg ccgctgcggt tgaaaaagaa ctgacaagta tcgaaccagt gattgctaac
     6481 acgattgagt cctttaaaaa aggtggacgt ctgatttata tgggagccgg aacaagtgga
     6541 agactaggtg tgttagatgc tgctgaatgc gtaccgacat tcggtgtaga accggaaatg
     6601 gtcataggtc taattgctgg tggagaagaa gcaatgactg tagctgtcga aggggccgaa
     6661 gattcttatg agctagggca agaagatcta atcaagctga atttgacaaa aaatgatata
     6721 gttattggta tcgcagctag cggtcgtaca ccatatgtga tcggtggatt agattacgca
     6781 aaatcgatcg gtgctgtcac aggaacgatt tcttgcaata aacaagccga aatcagtaaa
     6841 cacgcggatt tcccaatcga agtcgatgca ggtccagaat ttttgacagg ctctactcga
     6901 ttgaagtcag gaacagcaca aaaacttatc ttgaatatga tttctactat cagtatgatt
     6961 ggtataggta aagtattcaa taacttgatg gtcgatgtca aaccaacaaa tgaaaaacta
     7021 atcgaacgct caaaacgaat catcatgcaa gcgacagaag ctgattacga aacagctgaa
     7081 aagtactttg aagaagcaga tcaaaatgtt aagctggcta tcgtcatgat tttgacaaat
     7141 agtgataaag aggaagctca agcaaaatta gctgaagcaa acggatttgt aaaagggacc
     7201 ttatgagggg gaaaagacca tggcaaaaaa cgaactgact ttggaagaac tggcaaaaca
     7261 aatttataaa ggggcaggcg gcatgggcaa tgtagaaagc attgtccact gcatgactcg
     7321 tgtgcgtatg aagatcatca atgatgatct tgtaaatgtc tctgaattaa aagcgattcc
     7381 aggagtgctt ggtgtagtag aagatgaaca gcttcaagtc atcatcggac ctgggaaagt
     7441 gaacaaagta gcacagcaaa tggttgattt ggcaggcgtg aaattaggag aaaaactttc
     7501 ttctgtaagt acagctacag caaattcatc agcatctgga aaagaccgtg taaacgaacg
     7561 ggcacaagaa atgaaagcgg cacaaaaatc gaaacaaaaa ccatctaaaa tcaaatcggt
     7621 attaaaagac atttctaata tctttgtgcc aatgattcct gcatttgtcg gtactgggat
     7681 cgtggcaggg attgccgcag ttttagcaaa cttagtcaca gccggaacac ttgatgcagc
     7741 aacatggcaa caatatatcg atgtgatgaa catcttgaaa aacgggatgt ttagctacct
     7801 agttatctat acaggtatca atgctgcaca agtttttggt gcaacaccaa ctcttggtgg
     7861 agttatcggg gccgttgtga tgctgacagg gatgaatccg gaagcaccac tgaaaaactt
     7921 atttactggt gaagctcttg cagctggaca aggtgggatc ctaggtgtca tcttcgctgt
     7981 ttggctattg tcaatcgttg agaaaaaact gcataaagta gtacctgatg cggtagatat
     8041 catcgttaca ccaactcttt cattgattgc catcggtctg attgaaattt tcttcatcat
     8101 gcctttagca ggtttcattt ctgatggcat ggtcggtggg atcaactggg tacttggcgt
     8161 tggtggagca tttgccggct tcgttctagg cacattattc ttgccgatgg ttatgttcgg
     8221 actgcatcaa attttgactc caatccatgt gcaaatgatt gatgaaactg gtcgtacgct
     8281 attgcttcca attcttgcga tggctggtgc aggacaagtg ggtgcagcat tggcattatg
     8341 gattcgctgc aaaaaagata aagaattaac agaaatgatc aaaggagctt taccagtcgg
     8401 gatcctagga atcggcgaac cattgattta cggagtaaca ttacctctag gacgcccatt
     8461 tattactgct tgtatcggtg gaggtatcgg cggggcagtg atcggaatga tcggaaatgt
     8521 cggggctatc gctattggac cttcaggagc cgctttgatc ccattgatct ctgacggtaa
     8581 atggttaggc tacatccttg gattattggc agcttatgct ggtggcttcg ttgctacatt
     8641 cttcttcggt attcctaaag accgtttaga aaaagaagaa ttagcgactg aaacagccac
     8701 agtaaatgaa gtgcctgaaa aagtagtacc tcaaacttca gctgaaagtg tgactatcct
     8761 ctcatcagtt gctgacggaa cagttgtttc tttagataaa gcaagtgatc cagtttttgc
     8821 acaaaagatg atgggtgaag gctactttgt agaaccagaa aacggacata tctattctcc
     8881 agttactggg gtagtcagct ctgtcttccc aacgaaacac gctattggga tcacaacgcc
     8941 aaatggttta gaaatcttgc ttcatatggg aatcaacaca gttgacttag gcggtacgcc
     9001 atttgatgtg aaagtaacag aagggcagca agtgacacct gatacgcttg tagcagaagc
     9061 tgacttagaa gcgatcaaag cagcaggcaa agaaacatcc atgatcgtct tggtaaccaa
     9121 tatggatcgt gtaaaaaact ttgtcttgga aaaaacaggt aaagcaaaag caaaagcacc
     9181 tgtgatggat gtcaaagctt aatatgatag aaacaataga aacgaaagaa gaaactgaaa
     9241 tctatttttc agcttcttct tttttattat ttattgtttt ctgctaaaat ctgataaatt
     9301 cgtgtcacat cagatggtgt tccccgtaat tcataatctg ccaagaaagg aaagccaaat
     9361 gtttgtgcat attgtttggc tgttagacaa tactgattat tgaagttttt atttccgcta
     9421 ccgactacac caagacaaag tttatgattg tcttcatgtt ccagatattc acgcatcgtt
     9481 tcggtcaaga tttctgtatc accgttatct aaaccatttc cgccgtctaa ataagtagga
     9541 acgaaagtaa aaaatggttc tgtttctttc gtaaaatcac tattttcatg gatttctttt
     9601 aaagtaactt caggattgac aggatcttct gcatgcattt tttcagcata ttctgctaga
     9661 tgtttggcaa aggcacgcgt atttcctgaa atcgatatat ataaaatgtt catggatcat
     9721 cctccaattc tttcctttta gtatagcatc ttttttaagt tttttggtgg tgtaatttgg
     9781 aaagggacta ggcgctttgc ttgtataatg agaaaaaagc cggtagaatt atatttctat
     9841 taaagttttt attaattaag taaaaataaa aaaggtttgt tatacttttt gataaaagcg
     9901 gttttatttt ggaggatgct tacatggata cagagcaaca gaaaaaagga attggtttaa
     9961 ttccacttgc tgccttagta attggttcag cgattggagg tggcgtattt ggtattatga
    10021 cggacatctc cggatcggct ggcggcccag ctattttcag ttgggtactc gtaggaacag
    10081 caatgttgat gctctccttg tcgatcaata atatcaataa aaaacgtcca gatttaaaag
    10141 gcgggatctt tagttacgca gaagaaggtt ttggccgttt cgctggtttt atcagcggtt
    10201 ggggttactg gctcacatgc tggttaggca acgtagcttt tgcaacattg ttgatgagcg
    10261 cattaggata tttcttccca gtatttgaag gtgggcaaaa tctggcatcg atcgtgatga
    10321 gtacagtctt tttatgggga tatgcatggc tagtgaatcg gggagtcgaa aatgctagtt
    10381 tcgtcaatgc tatcgtcaca ttctgtaaat tagtgccatt atttttattt attgtagtag
    10441 ctatcagcac gttttcgatc caacaattca ttgataactt ttctagcgac attatattga
    10501 atgcgaatgg acagccgatc ccgttttcca gtcaagtatt gagttgcatc atggtgatgc
    10561 tttgggtatt tgttggtatt gaaggagcct ctgtcgtagg ttcacgagca aaaaaacaat
    10621 cagatgttgg gaaagcaacg attctaggga tattcggctt gattattatt tacgtcttgg
    10681 tttccatgct tccatatggg acaatgacga tgaatcagct gcaaacgatc aaggcgcagc
    10741 ctgctatggg ctatgtgttt gaaatgatgg ttggtaaatg gggagcagtc gtgatcaacg
    10801 gcggtttgat catttcttta gttggtgttt ggctctcatg gacgatctta ccgattgaaa
    10861 caatgggaaa catggctgaa gacggacttt tgcctaaagc atggggaaaa ctcaacaaaa
    10921 atggggcacc aacttatgct atcgtattga cgacgttatg tacgaatgtc tttttacttt
    10981 cattattatt cactgacagt gcttataact ttgcttacac acttggtaca gcagctattt
    11041 tcttcacgtg gcttttctta ggattgtacc aaatgaaact ttcttatcag cggaaagaat
    11101 gggtccaatt tttagtaggg cttttagcaa gtgcctttca agtatgggct atgctagtcg
    11161 tagcctttaa tgaagtaatg cttgttcttg ttcttttctt gccaggcatt tatttttacc
    11221 tcaaagcacg taaggagcaa aacgagcctg tacaacatat ccacttagat aagattttac
    11281 ttataggtgt gacgatggtc ggagtgattg caatggtttt atttgccact gggatgcttc
    11341 acgtatagaa gtataaaaga agtataaaga gaggttgtga gcctgtcgtt tattcaaaaa
    11401 catactagga aaggagctgt gacacaaatg ttgtcacagc tcctttttca gaataaacgg
    11461 tgtttaagag acagccaatc ggcaataagg ctgaacgtct ctttcacagc ctcttttttg
    11521 atgagtcatc atacattttt tcgcttaaat acgagatatc ctaatgctaa gaacaaaacg
    11581 atgtaagcta aattaccgaa tagcatttga ttagtagaaa gatgagtcaa ttgcttcatg
    11641 atctcttcgt ttccaatttg gttttgcaga ttcaacatac tgatcggatt ccatttgatc
    11701 cactcccatt tttggatgag tgcaataagg ataccagata tgattgacga agcaaaataa
    11761 aagacgattc ctgctgagat ggatgcgccg gaactattga taaagcaagc aatcatcaac
    11821 actaaactta aaatcagcca taaaccgata taactaccca aagtataagt gaacaagctt
    11881 tggatcagtg tttgaccagt agaaaccttc tccgtgaagg aaatcgaagg gaaaagaatc
    11941 agtttcatca acacagtgac aataatagct aaaaggtata aataaacaga ataaataact
    12001 aatgtgatcc atttgcttac taatatttct cctcgagaat actttcgata aaggagattt
    12061 ttcaatgtac catattgtgc ttccatcgaa atgatcgtgc ttgcagctgc aatcatgata
    12121 aagacaatcc aagatgtggc actaaaaagc tgagcagtca tttcaactgg atcaatgatc
    12181 gtcgtgtatt ttttggctag aagtgctgtt cctatgagca aaacaactaa tagaacagat
    12241 aaaacagcag ttgacttttt cttgatcaat ttaaataatt cttgttttac aagcaatgtc
    12301 atttttcttc ttcccccttt actgaatcca gaatttccaa tagagaagat tccaaatcat
    12361 tcgtcagatg ctggacgtct gtcacatgga tattttgtgc agacaatagc tggatcacgg
    12421 ttcctaataa ttcttcgttt tcttttaaaa gcttgatttt atcaggatct tccaaagtat
    12481 atccagcttc tgtcaagatc gttcgagcag ctagatcatt tgttgtagag ataacgatga
    12541 aatcttgcgc tgtttggttc aattcagcca ttgtacattg tttgatgatc tttccttgat
    12601 tgatcaggat cagctcatcg accatttttt caagctcgct gagtaagtga ctggagatca
    12661 agaaagaggt gccctgagta gccaagtcgg taatgatttt tcgcacatct cttgttgctt
    12721 gtggatccaa accgttcatc ggctcatcta aaataacgat agacggatgg ttcagtaagg
    12781 caagagcaat tcccaatttt tgtttcattc ccaacgagta ggatttcgct tttttgtgaa
    12841 tgtacttttc catcttgagc tgattcacga tagtgtcgat agcagataca tcgttggttt
    12901 cagagaataa cttcagatga tcatagcctg ttaagaatgg atagataccc gggtattcga
    12961 tcaatgctcc tacttgttcc aaccctttat gactagaggg agaaatctca ttttcaccaa
    13021 tacagattgt tccatctgag taatggatca gtcctaaaat agctttcatg atcgttgttt
    13081 ttccagcgcc attaggacct actaatccaa cgattttgcc aggggataag ctaaaactga
    13141 catcgctgag ggcttgtttg tgaccaaagt tcttggataa ttcttggacc gaaagacttt
    13201 tcaaaaatat tcactccttt tctatagata gtacaagcat acacctgatg agtggagaag
    13261 tcgctaggtc attggactta tttcttattt tttcataaaa aaattgaata ttaaataaaa
    13321 aggcttattt tttctgatca gtacttattc caagtgtcta gtggccgcta gtaatcttga
    13381 tgccaatgat actgatgagt agcatcccca caaagaacca agtggaaaga ttcagcttat
    13441 catgaaacaa gaccacacca attatgaccg aaccaactgc gccaatccct gtccagatag
    13501 gataagagag actcatcggc aaacttttga ttgcctttga caaaaagtaa aaactagcaa
    13561 tcatgccaat cactgtgtaa aaagaataat tgattttaga aaaaccatca ctccatttca
    13621 tcatcgttga ccagaatact tccaaaattc ctgctatgat taattccatc catgccatac
    13681 ttacattcct ccttaactat aaaaaaatac acaaaaagag gaaaatcatc ccttcaaaga
    13741 cctaatggaa tgatcatcct ctttatccta cccggtggca gattgtatat ctttttctgt
    13801 agtatagcac acctatccag atatcggcaa tctcatactt tttagtaaag tgtaccaagc
    13861 actgacggat atatcgttag cggaaaagaa gatgaatgct ttgcaatttc atagaaagaa
    13921 gttgttattt attaatcatt taaaaaaaac agta
//
LOCUS       DAZAOD010000267         4392 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.149, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000267 DAZAOD010000000
VERSION     DAZAOD010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.149"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            342..1820
                     /gene="msr(C)"
                     /locus_tag="ACHDPO_003075"
     CDS             342..1820
                     /gene="msr(C)"
                     /locus_tag="ACHDPO_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFN3370602.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1867..2313
                     /locus_tag="ACHDPO_003076"
     CDS             1867..2313
                     /locus_tag="ACHDPO_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFN3370603.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2512..3027)
                     /locus_tag="ACHDPO_003077"
     CDS             complement(2512..3027)
                     /locus_tag="ACHDPO_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFN3370604.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            3144..4346
                     /locus_tag="ACHDPO_003078"
     CDS             3144..4346
                     /locus_tag="ACHDPO_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFN3370605.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1320 a          735 c          950 g         1387 t
ORIGIN      
        1 tactattcag tagctattgc tttttttgaa tcgtgtgtgg taacctaata aaaaaggagg
       61 tcggaaaaat gactgcatcg atgaaattac gtttcgaact tttgaataac aactaaataa
      121 attcaaaaga catgtataaa caacaatttc atggatggag tatgtccatt ttttcgaacg
      181 acagtagaat aggtgaaagc tatgacagat ttggtgattt agtcatagtt atttcgttca
      241 gagtaggaaa agatgtgatg cagttttttt gcaaacagat ttttctgctc ttttttagta
      301 tcgataattg ttgttttaca tgaaatagga gtgtaaaaca tatggaaaat ttagcagtaa
      361 atataacaaa tctacaagtc agctttggca accagctaga actatctatt gattctcttc
      421 gtgtctatca gcaagatcgt atagggatca taggagaaaa tggtgtcggt aaatcgactt
      481 tgctcaaact aatagccggt gaactttttc ccgatcatgg gaaaatccaa acagagatca
      541 ccttcaacta cctgcctcaa ttaacctatc tcgctgaagc aaaggaccta aatttggaat
      601 tagccagtca tttccagtta agactggaag aaacttcaga gcggaaatgg agcggagggg
      661 aagaacgaaa gatcgagttg atacgtcttc tttcttctta tgaacaaggg atgcttctag
      721 acgagccaac aacccatcta gatagaaaaa gtattgatcg actgattgaa gagcttcgtt
      781 attattatgg tacgctggtt tttgttagtc atgatcgcta ttttctagat gagctagcat
      841 cgaaaatctg ggaagtaaaa gacggagaaa tccgagagtt ttcggggaat tatagtgcct
      901 atctcactca aaaggaattg gagaaaaaga ctcagctacg agaagcagag tcgatcatga
      961 aagagaaaaa acgattggaa aaatcgatcc aagaaaagaa aaaacaagcg gaaaagttgg
     1021 aaaaagtgtc cagtaaaaag aaaaagcaac aaatcagact ggatcggttg tcttcctcta
     1081 aacaaaaaga cagtgtacaa aaagccatcc aaaagaatgc gaaaacatta gagagaagac
     1141 tccaaaaaat aggagaaaca accaagccgc agcagatgaa acaaatccgt tttccagtac
     1201 caaaatctct tgaactccac agccgctatc ccatcatggg acaaaatgtc caattggaaa
     1261 gaagtgggag aacattactg gtaaatggtg attttcagtt ttctttaggt aaaaaaatcg
     1321 cgattgtcgg tgaaaatggt tcaggtaaga caaccttatt agaacatatc cgcaaacaag
     1381 gagaaggaat ccttctctct ccgaaagtaa gctttcaagt atatcagcaa aagggttatc
     1441 aaatgacatc tgaagaatcc atcattcgtt ttgtcatgag acaaacagag ttttcagaat
     1501 cgcttgtccg tagtttgctg aatcacttag ggtttgctca ggaaactttg acgaaaccgt
     1561 tatgtacatt aagtggggga gaagcgaccc gtctgacgat tgctttgctt tttactaagc
     1621 caagtaatgt gttgctgtta gatgaaccga ctaattttat tgatatggca acgatcgaag
     1681 ctttagagaa gctaatgcaa atatatccgg gaacgatttt gtttacttct catgattctt
     1741 actttgtcga gcgtacggct gatgaagttt atgaaataaa agggcagaaa ataaaaaaag
     1801 tacttacgag aaatttttaa atgtgctacg atgattttcg tgacaaattt aaaggagtgg
     1861 tacagattgc ctacaaataa aaaagaagga ataattttta caacaatgat gtgttttttg
     1921 atggtcttgg ggatgagcgc gtataattta tggctgcatc aagatcttca tttatcaagt
     1981 ttgttgattg gtctagtgcc tggattcgtg gtggctttca ttttggatgt cttcatcatc
     2041 ggtgtgctgg cgaaaaaaat tgcctttaaa ctaccagtaa atccagaaag caaggtccaa
     2101 atgatcttaa ctatttcatg cttgatggtt ttaggaatgg tgacatgtat gtctttattc
     2161 ggtgtgatca tggaacaagg aatacctgat caattattct ctgcttatat gaatgcttgg
     2221 aaaatgaatg tgattgccgc tttaccgttg cagttgatca tcgttggccc gctttcaaga
     2281 agtgtgctaa aagcaattca aagtaatgaa tgatggaaca ctgttatttg aaaaaaggcc
     2341 ttggcatgct ttttgtcata gtctcttgaa tgcagttcta gaaaaatagt gatccgaacg
     2401 ataggttttg gcctgtcgtt cggatcgctt tttcttttcc aactgtattg ctcttttatt
     2461 gaagataatt tgctcttcaa tagatatttc tagaaaggtt ctgtttatcc cttactcaaa
     2521 aaactgctgc atttgttctc ttacttgctg acaccattgg agttcctgct gacaaagcat
     2581 aattctgcgc tggatcacaa cataacgtcc aaattcttgt ttcttgtcta gcgagaggtc
     2641 attcaatttt ttttgatttt tttgcatgat tttgttcagc tgttgttctc tagtgaatag
     2701 cagtccagta gctgttgttt tatcgagcgt cgaaaaagca tagatttttg ctagaaattc
     2761 atctttttgc gtaggagcgg gagtttcctc tttgatccat tcctctacaa gagcacgtcc
     2821 ttcatcagtc aagtggtaga tctttttttg agagtgctcg tctttgtcca aaacggtcac
     2881 ataaccctgc tggtctaact tggcaagcgt tgtatagatc tgactgtgat gggcttccca
     2941 aaaaattgtg atcagctgct tcaattcata cccagaacgt ggtttggata aaagcacgca
     3001 taataatata taggctaaag tattcataaa aatcctacct ctcgtcttat tttctttatt
     3061 atatcacagt aaagtttcca cgttttacat gtgcatattg acatgtaaaa taaatcatgt
     3121 atgatgctaa tagagagaaa gggatggaaa tattggagaa tcaaatagat atacaagaac
     3181 aaacaaatga agaaacaaag gggaaaagtt cagcgctagt tgtagcagct acctgtatga
     3241 tcgcttttat gggagtgggt ctagtagacc caatcttaaa aacgattgct gcacagttaa
     3301 acgctacgcc agctgaaacg accctgttat ttactagtta catgttagtc actggtgtgg
     3361 tgatgctatt tacaggtttc ttatctagtc ggatcggttt gaaaaaaaca ttgatgacag
     3421 gattgtttat catcgttgta ttcgctggtc ttggcggatt atctgggaat atcggaatgc
     3481 tgattgggtt acgtgccggc tggggtgtcg ggaatgcttt atttgtctct actgctttag
     3541 caacgatcgt cagtatttta gttggtaaca cagaaaaagc aatcatgatg tatgaagcag
     3601 cacttggctg cggaatggct gttggccctc tagtcggtgg ggtcttgggc agtggttcat
     3661 ggcgttatcc attttttggg gtagcatttt tgatgttttg cggttttata gccctagcgg
     3721 tacttttacc tgaaactgag aaaccaaaga gaaaagtagg cctttgggaa ggtgtcaaag
     3781 cgttaagcaa tcataaactt cgttcagttg gactaatcgc attgttatat aatttcggat
     3841 tctttacttt acttgcgtat gcgccatttt tattgattgg ctattctgaa ttagaagtcg
     3901 gttttgtatt ttttggctgg ggtgtgcttc tggctattgc ttcgattttc gttgcaccgg
     3961 ctcttgagcg gaagtttacg acttatcgga caattttagc agcatttgtc ttattcatta
     4021 tttgtttgct gttattagga gctggaactt ctatgccagt ccttgtaccg atcagcattg
     4081 tgttagcagg atttttccaa ggaattatca atacactgtt gacgacgatt gctatggaaa
     4141 taccaggtct gcaacgaaac gttgcttcgt ccagctatag ttttgtccgc tttttcggtg
     4201 gagctttagc accatttatt gcaggtgtga ttggtgaaca tattggtgaa agctatgcgt
     4261 tttattttgc aggtgccatt gttcttatca gtgtatgttg tatcatttat caccgtaatt
     4321 attttgctac aaatgaagaa gaataagaaa tcagaggttg tgaaaaagct gtcctgcatc
     4381 aagtcataag aa
//
LOCUS       DAZAOD010000268         3796 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.164, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000268 DAZAOD010000000
VERSION     DAZAOD010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.164"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            110..193
                     /locus_tag="ACHDPO_003079"
     CDS             110..193
                     /locus_tag="ACHDPO_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFN3370606.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="ACHDPO_003080"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="ACHDPO_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFN3370607.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="ACHDPO_003081"
     CDS             complement(1318..2181)
                     /locus_tag="ACHDPO_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFN3370608.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="ACHDPO_003082"
     CDS             complement(2183..2455)
                     /locus_tag="ACHDPO_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFN3370609.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="ACHDPO_003083"
     CDS             complement(2472..2681)
                     /locus_tag="ACHDPO_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFN3370610.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2759..3655)
                     /locus_tag="ACHDPO_003084"
     CDS             complement(2759..3655)
                     /locus_tag="ACHDPO_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFN3370611.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
BASE COUNT         1174 a          662 c          586 g         1374 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattct
     2761 attctttttc attttctaat tgaatgattc gctcaatcat ttcaaaaaat acgttctcat
     2821 acatagacaa aacttttttg tcatagcctt tgtgttctgt aatgccattt ttagaccaag
     2881 tacttacttt attacttcgc ttgataatat ttcggaaaac caaattatcc tctttatgtt
     2941 ctttgtacag ttcttccagg tttgatttta tcgttgcgct gtccgtatca actaaataag
     3001 gaacaaaacc aatcatatct agtccagggt taaactgttc ttgcaaatca atcaaatagg
     3061 aaatatagtt ttgaatgttg tttgtacttt cttcttctgc ttgtaaaggg atcataacgt
     3121 aatcactcgc cacgattgca ttatttgtat aaacgcttgg cgttggtaca gtatcaataa
     3181 taataagatc atagtcactt tttaaaggtg ctaaaagagt agcaagcaat ctactttcat
     3241 tttcaaacgt ccatgagcga gttaattttg gcagtaacat caaatcaaac gtgccaggga
     3301 tcaagtctaa attatcagtc aaatgaataa tagaagaagc caagtttcca tttttcaagc
     3361 cttcataaaa attgacacgt ggcaattcta cctcaaaagt ttttgctaag tcttttgtca
     3421 atgttgcctg taagtcctta tcgatcatta aaacttttaa attcaatttg tctgtcaagt
     3481 aagcaaacat agtcgataat ttggactttc caacaccacc tttaaagtaa ttattcaaga
     3541 taataattgc ttcattttta ttgtttaaaa tacgtcttaa ttcttcaagt atttttagtt
     3601 tttccttctc cataactacg ccccattctt tttttgtata gtaatattgt atcattaaga
     3661 atcacaaatc acaagtgatt tgtgattaat cacttgtgat ttgtgataag tgatttgtga
     3721 ttaatatata aaagccctct ttaaagggct tttataggtt ctgttgcaaa gttttaaata
     3781 aagaataaaa tccctt
//
LOCUS       DAZAOD010000269         2561 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.179, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000269 DAZAOD010000000
VERSION     DAZAOD010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2561
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.179"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            120..617
                     /gene="dfrG"
                     /locus_tag="ACHDPO_003085"
     CDS             120..617
                     /gene="dfrG"
                     /locus_tag="ACHDPO_003085"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFN3370612.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(689..>2561)
                     /locus_tag="ACHDPO_003086"
     CDS             complement(689..>2561)
                     /locus_tag="ACHDPO_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFN3370613.1"
                     /translation="DRAKQYDLLTPKRFATRYNKMLFLPTSFKWNGSEYPIQYNYCIN
                     PFCCNFGKEQHKFKDVKGKPSRYKMTGSSKDKGHKGMYCNDNPIGRGVSQNCTVTPLS
                     NWSVVEEIKRLIEINSIQDVEPDYQFHKEGCSEEESTPFNEPKQFYKRGKSRGKSQRY
                     QCKACKKFTNVLPKREETTTYHQQKNTILPMFAKMVVGRVSVSRTCDILGIGVGTYYH
                     KLEWLYRRCLEFLERYETQPLQTKKFNEMWLNTDKMHYYLNNVRKKGQGSKKYTGFED
                     LNMQTYIVVSAEVLSRYVFRSDVAYDWNISMDELNEDTRKFKEDHLNTFSRKNDRLDW
                     SYYPQEPSANDSENRNAYLHELGKITNRSRFVDGLNVDAPYTTTAHYWLIKQMVNADE
                     WRMISDDDFSIRNAFYRVFTKELRLSDAHHFICQVNKTKSRKQCLKEFGQAKAELLDW
                     GDIRGFKTKFLRTLASHYLTELLTSHQFHEEAISKDGERYRKYADNPIKHPLATKDKG
                     FYSVDCRTDLSALEPNEIAKMLLNVNDHSTNSFIQQIRRYISSLERPLTTARGDKKSY
                     IYANFNPKYAQFAITILRTYYNFCRPFKSADKKVLTPAQRLGITDKQFDWKDIIYFK"
BASE COUNT          792 a          431 c          456 g          882 t
ORIGIN      
        1 tgataatata acttatagaa aaaattgctt attcaactaa cgggcaggat aatgagaaaa
       61 ggttttttga tagaaataag aaattagatg gtaaattagt taaaaaggct gtgttataaa
      121 tgaaagtttc tttgattgct gcgatggata agaatagagt gattggcaaa gagaatgaca
      181 ttccttggag gattcccaag gactgggaat atgttaaaaa tactacaaag ggacatccga
      241 taatattagg taggaagaac cttgaatcaa tcggaagagc cttacctgac agaagaaata
      301 ttattctgac gagagataag gggtttacct ttaatggttg tgaaattgtt cattcaatag
      361 aagatgtttt tgagttatgt aaaaacgaag aagaaatttt tattttcgga ggagaacaga
      421 tttataattt gtttttccct tatgttgaga aaatgtacat cacaaaaata catcatgaat
      481 tcgaaggaga tacttttttt ccagaagtga attatgagga atggaatgag gtatttgccc
      541 aaaaagggat aaagaatgat aaaaatccgt ataactacta ttttcatgta tatgaaagaa
      601 aaaacttatt gagttaacgg gtgcgttaat tgaagaagaa cagtaaagat aaagcacaag
      661 agcttgggat tactccaagc tctttttgtc atttgaaata aattatatct ttccaatcaa
      721 attgtttatc tgtaatccct aatctttgag caggtgtcaa aaccttttta tccgctgatt
      781 taaaagggcg acaaaagttg tagtaagttc ttagaattgt aatcgcaaat tgagcatact
      841 tcggattgaa gttagcgtaa atatagctct tcttatcacc acgagctgtt gttaatggtc
      901 tttcaagaga tgatatataa cgtcttatct gttgaataaa gctattggtc gaatggtcat
      961 taacatttaa tagcatcttt gcgatttcgt ttggttccag agcagataaa tccgttctac
     1021 aatcaactga ataaaatcct ttatccttag tggctaatgg atgtttgata gggttatcgg
     1081 catatttgcg atatctttct ccatctttac taatagcctc ttcgtggaat tgatgacttg
     1141 ttagtaattc agttagataa tgagatgcca aagtccgtag aaactttgtt ttgaatcctc
     1201 tgatatctcc ccaatcgagc agttctgctt ttgcttgtcc gaattctttt aagcattgtt
     1261 ttctgctttt cgtcttgtta acttggcaaa taaaatgatg tgcatcgctc aaccttaatt
     1321 ctttcgtgaa tactctataa aaggcgtttc taatagagaa gtcatcatca ctaatcattc
     1381 gccattcgtc ggcattaacc atttgtttaa ttaaccaata gtgagcagtt gtagtataag
     1441 gagcatcaac atttaaacca tcgacaaatc tactcctatt agtaattttc cctaattcgt
     1501 gaagataagc attcctattt tcgctatcgt tagcggatgg ttcttgtgga taataagacc
     1561 aatctaacct atcattttta cgactaaaag tattgagatg gtcttctttg aattttcttg
     1621 tatcttcatt taattcatcc attgaaatat tccaatcata ggcaacatca gaacggaaca
     1681 catatcttga taagacctca gcagatacaa ctatatacgt ttgcatatta aggtcttcaa
     1741 accccgtata tttctttgaa ccttgtcctt tcttacggac gttatttagg tagtagtgca
     1801 tcttgtccgt attaagccac atctcgttaa atttctttgt ttgaaggggt tgtgtctcat
     1861 atcgttctaa aaactccaaa caacgcctat acagccactc cagcttatga tagtaggttc
     1921 caactccaat tcctaaaata tcacaagtac gactgactga aacccttcca acaaccatct
     1981 tagcgaacat tggaagaatg gtgttctttt gttggtgata agtagtggtt tcttctcttt
     2041 ttggtagaac attagtgaac ttcttacacg ccttacattg atagcgttga gatttgcccc
     2101 tacttttccc ccttttgtaa aattgcttcg gctcattgaa tggggttgat tcttcttccg
     2161 agcagccttc tttatgaaat tgataatctg gctcaacatc ttggatgcta ttgatttcta
     2221 taaggcgttt aatttcttca acaacagacc aattagataa aggggttact gtacagtttt
     2281 gcgatacacc tctgccaata ggattgtcat tgcagtacat acctttatga cctttatctt
     2341 tggaactacc agtcatttta tatcgacttg gtttcccttt tacatctttg aatttgtgct
     2401 gttctttccc aaaattacaa caaaacggat tgatgcagta attatattga atgggatatt
     2461 cagaaccgtt ccatttaaaa gacgttggca agaacaacat tttgttatac cttgttgcaa
     2521 atcgttttgg agttaataaa tcatattgtt tagccctatc t
//
LOCUS       DAZAOD010000270         1877 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.199, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000270 DAZAOD010000000
VERSION     DAZAOD010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.199"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            283..1521
                     /gene="mef(H)"
                     /locus_tag="ACHDPO_003087"
                     /gene_synonym="mefH"
     CDS             283..1521
                     /gene="mef(H)"
                     /locus_tag="ACHDPO_003087"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFN3370614.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
BASE COUNT          584 a          264 c          334 g          695 t
ORIGIN      
        1 ttgcagaagt tatcatggta ttaagtaatg tatggctcaa cccattagtt gaaatgacgg
       61 ataaagaggg tatggaaaaa cgttgcaata cattcaatgc ccttttaaat ggaataggca
      121 tagacacatt attagacgaa gaaacaattt ctgcatttat acagttttgt aaataactgt
      181 atttgttatc cctatacgat agactgctct ataaaagagc agtttattta aaccattata
      241 taaaccgacg gtctgtttga ttaaataaaa aggagagatt ttatgcaagc agaaaaaaaa
      301 ctttttaatc gtgattttat acttgttgtt ataggacaga taatttcttt atttggaaac
      361 gctatcctac gatttgcatt accgtactat ttgttaaaag aaactggttc atcagctttg
      421 tttggtattg ctacagcctg ctctttttta cctatggtta ttttgtcgct ggtaggtggt
      481 attattgctg acaggacaaa taaaagaaac attatggtca tactagattt tgtaacagca
      541 atcataattt tagtatttta tttgtcattg ggaaaaattc ctatcatacc tttgtttatt
      601 gttgctttga tgttacttta tggtatttct ggtgcatatc aaccagcggt acaagcaagt
      661 attcctctat tggtatcatc agataaactt accgtcggta atgctataat aaatcaagta
      721 aatactttag caaactttat cggaccagct ataagcggag tagtttttca attttatggt
      781 atcaatccca ttttaattgt tagtattata tgttttactt tttcagccat tatggaaatt
      841 tttatccata ttccacacca aaaaagacct cgtgaagtag gtgtaattgc agttgctaaa
      901 aacgatttaa aagatagtta tacctttttg aaaaaggaga aacccatttt tatatccgta
      961 atctttttgg tttgcatttt caatttggtt ttaagtgctg ttttaattgt tggtctgcct
     1021 atcttaattt ctgaagtttt aaaaatgcca gatacactat atggtttttc acaatcagca
     1081 ttatcattag gtggtttatg tggtggtatt ttaacagctc ttgttgcttc aaagttaaaa
     1141 ctaaaaaacc tttatacctt gttacttatt tgttctgttt ctgttttact tatgggaatt
     1201 tcgctatttt tagaattgcc tgcaatagtt tcctactggg tagttacagt gatgtgcttt
     1261 gtggctatgg gtgtatctac tatgtttgtt gttcaaattt acactcttgt tcagacacaa
     1321 acaccaccgc aattagtagg aaagataatg gctacgctgg tagcagttgc tatgtgcggt
     1381 caacctattg gacaaatggt ttacggtatt ttattcgatg tatttataca agaaacatgg
     1441 gttgttatgt ttgtagcttc tattgcttca atcatgattt caatatattc aaaaagaatt
     1501 tttcaaaagt tagagatata atacaagggg ttaaatagta tgttaggcta aaaacaatat
     1561 ataaaagaaa atttgaaatc tgctaaaagg atagtgttat aaaagaaaga gtaatattgc
     1621 agtatttaag gctcgcacaa atatatgttt tgtgtgggct tttttcttac catttttctg
     1681 tatttctaaa gggtataaac ggtattccgt ttatatattt cagcattagc agaaaggggg
     1741 tgagattatg aggacatctt ctttcgagca tatcgtcaga ttacagttca attctttaat
     1801 gctgattgtc attaagaaca aagtgaaaag tcgaaacaga cagcttgcaa gacattctaa
     1861 acgtgaagta ttgtttt
//
LOCUS       DAZAOD010000271         1637 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.210, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000271 DAZAOD010000000
VERSION     DAZAOD010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.210"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..352
                     /locus_tag="ACHDPO_003088"
                     /pseudo
     CDS             4..352
                     /locus_tag="ACHDPO_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(624..914)
                     /locus_tag="ACHDPO_003089"
     CDS             complement(624..914)
                     /locus_tag="ACHDPO_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370615.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1316..1552
                     /locus_tag="ACHDPO_003090"
     CDS             1316..1552
                     /locus_tag="ACHDPO_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370616.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT          547 a          281 c          285 g          524 t
ORIGIN      
        1 taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca aaaaaatttc
       61 attatatcca gaaaaatttt tcttagttaa ggacctatgg attgcagtaa tgcagaattc
      121 gtcgaataaa ctgccaaaga catacaatca tattgctttt aaaattgacg aacaagatat
      181 agattcgttt gtctcaaaaa tccaaatgtt aggtttaact gtcgaaccag gacgttctcg
      241 tgtgaaaggc gaggcttctt caatttactt ttacgactat gataatcacc tcttcgagtt
      301 acataccggt actctccagg aacgtttaaa atcctacaat tccactacct gagactagta
      361 atgactagtc tctttttatg gcctctgatc cccccattga gcgaatacta atagggcttc
      421 gaattgatct gttcaatctt taagcaatat ccctcaaatg agtttggaaa gtttagtgat
      481 tcatcacaaa tacttaaata catgtagtta tatatagatt gaggttcttg tgagcgtatg
      541 ctcgtgtggg ttcaaatccc atcgtctgca tccatctttc caaaacaagc ggctaggaca
      601 tttttgtctc agccgcttgt tttctagttt attctttcat cttgtcggac cttttttctt
      661 gggtatagac ttttctcata ttctaccaca attttgggtt tccctaacac atgataggat
      721 ctcacaacaa attgctttct attattataa taacctgtaa cgactaactt catcccttcg
      781 tctacttcag ctaggaagtt caaactatgg gaagcaatca aacaattgac cccatttaaa
      841 ctgaaacgga tcaacggtct ggcactaact tgcaaagtac ggatcttatc tactgttcca
      901 tattttttct ccataacctt cacctcaata ccattatacg aacatacatt ccctttgtaa
      961 agaagaaact ctgttttatc tttttgactt tttgtctatt acctttctta aaatcatatt
     1021 ggcacttcct gcgaagatga aggacatgta ctaaaaaaaa gaggcagcag tatagattta
     1081 agtagttcag ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc
     1141 aactgaattt gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac
     1201 aaaatgtaag ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca
     1261 aattggtgtg ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca
     1321 atttcttgag ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt
     1381 aagggtgata gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga
     1441 tgaattctta ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg
     1501 aagtaataag cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat
     1561 gaccaagctt aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat
     1621 ttcaaacgaa gaattaa
//
LOCUS       DAZAOD010000272         1620 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.213, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000272 DAZAOD010000000
VERSION     DAZAOD010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.213"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..335
                     /locus_tag="ACHDPO_003091"
                     /pseudo
     CDS             1..335
                     /locus_tag="ACHDPO_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324676.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(607..897)
                     /locus_tag="ACHDPO_003092"
     CDS             complement(607..897)
                     /locus_tag="ACHDPO_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370617.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1299..1535
                     /locus_tag="ACHDPO_003093"
     CDS             1299..1535
                     /locus_tag="ACHDPO_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFN3370618.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT          540 a          279 c          284 g          517 t
ORIGIN      
        1 tttgatgcaa aagaaatcta cgatagtcaa caaaaaaatt ttcattatat ccagaaaaat
       61 ttttcttagt taaggaccta tggattgcag taatgcagaa ttcgtcgaat aaactgccaa
      121 agacatacaa tcatattgct tttaaaattg acgaacaaga tatagattcg tttgtctcaa
      181 aaatccaaat gttaggttta actgtcgaac caggacgttc tcgtgtgaaa ggcgaggctt
      241 cttcaattta cttttacgac tatgataatc acctcttcga gttacatacc ggtactctcc
      301 aggaacgttt aaaatcctac aattccacta cctgagacta gtaatgacta gtctcttttt
      361 atggcctctg atccccccat tgagcgaata ctaatagggc ttcgaattga tctgttcaat
      421 ctttaagcaa tatccctcaa atgagtttgg aaagtttagt gattcatcac aaatacttaa
      481 atacatgtag ttatatatag attgaggttc ttgtgagcgt atgctcgtgt gggttcaaat
      541 cccatcgtct gcatccatct ttccaaaaca agcggctagg acatttttgt ctcagccgct
      601 tgttttctag tttattcttt catcttgtcg gacctttttt cttgggtata gacttttctc
      661 atattctacc acaattttgg gtttccctaa cacatgatag gatctcacaa caaattgctt
      721 tctattatta taataacctg taacgactaa cttcatccct tcgtctactt cagctaggaa
      781 gttcaaacta tgggaagcaa tcaaacaatt gaccccattt aaactgaaac ggatcaacgg
      841 tctggcacta acttgcaaag tacggatctt atctactgtt ccatattttt tctccataac
      901 cttcacctca ataccattat acgaacatac attccctttg taaagaagaa actctgtttt
      961 atctttttga ctttttgtct attacctttc ttaaaatcat attggcactt cctgcgaaga
     1021 tgaaggacat gtactaaaaa aaagaggcag cagtatagat ttaagtagtt cagttttgga
     1081 gtacaaaaag tgaaaatgta aacctaaatg agtatcaaat tgcaactgaa tttgatactc
     1141 gttttttatt gttaaatcaa cgtttgttgt taatttacac cacaaaatgt aagttaaaat
     1201 gtatataaaa atgcgaacgt gaaataatta ttgtaggaat gcaaattggt gtgttaaaat
     1261 ggttacaatt tactaagcaa aaaggggtgc attttcctat gcaatttctt gagccaaaaa
     1321 ataagaacgc taagtctgtg gattgggaaa tatcagagca agtaagggtg atagttaagc
     1381 aatacgctga atatgcagag cgtactgaaa gcgaagcagt ggatgaattc ttattgaaca
     1441 ttttagacga taagaagttt attgaatgga ttgccaacaa gcgaagtaat aagcggattg
     1501 ttgaaaaaat gggtatcaaa gatagagtgg gttgatagac aatgaccaag cttaaaagat
     1561 tagccacgaa ggaagatgaa attgtagatg ttaaaattcc gatttcaaac gaagaattaa
//
LOCUS       DAZAOD010000273          804 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5116
            SAMEA115707503-rid22671003.guided.252, whole genome shotgun
            sequence.
ACCESSION   DAZAOD010000273 DAZAOD010000000
VERSION     DAZAOD010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707503
            Sequence Read Archive: ERR13197232
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002296209.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002296209.1
            Genome Coverage       :: 144x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/19/2024 01:46:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,094
            CDSs (total)                      :: 3,029
            Genes (coding)                    :: 2,949
            CDSs (with protein)               :: 2,949
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 36 of 80
            Pseudo Genes (internal stop)      :: 25 of 80
            Pseudo Genes (multiple problems)  :: 11 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707503-rid22671003.guided.252"
                     /isolate="VRE5116"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            191..739
                     /gene="aac(6')"
                     /locus_tag="ACHDPO_003094"
     CDS             191..739
                     /gene="aac(6')"
                     /locus_tag="ACHDPO_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFN3370619.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          285 a          121 c          174 g          224 t
ORIGIN      
        1 ttcctccaat tgatggcttt cctgatcttt cctattttga ataaagtgtt tctgtataat
       61 tttttatttt ataagtaaga taaataatga aagaatagag atactgattg gtagctaaag
      121 atttttgagc gagaacattt cgttttttca aaaggactgt tagaataagc aagaacaagg
      181 gggaagacgt atgataatca gtgaatttga ccgtaataat ccagtattga aagatcagct
      241 ttctgattta ctgagactga cttggccgga agaatatgga gacagctcgg cagaagaagt
      301 agaagaaatg atgaatccag aacgaatcgc ggtagcagcg gtagaccaag atgagttagt
      361 aggatttatt ggtgcaatcc ctcaatacgg tatcacaggt tgggaattgc atccattagt
      421 tgtagaaagc tcccgacgaa agaaccaaat aggtactcga ttagtcaatt acttagaaaa
      481 agaagtagct tccagaggag gaatcacgat ttatttaggt acggatgatt tagaccatgg
      541 aacaacgtta agtcaaacgg acctgtatga gcatacattt gataaagtgg cttccatcca
      601 gaaccttcgt gaacatccgt atgaattcta tgaaaaatta ggttataaaa tcgtaggtgt
      661 cttaccaaat gcaaatggct gggacaaacc ggatatttgg atggcaaaaa cgattattcc
      721 tcgaccaaat tctcaataat aaaaagaggt tgtgacagaa gtaatcagct tcaagaaata
      781 agaaggaatt tacgaaaatt actt
//
